clinicaltrialsgov-mcp-server 2.6.0 → 2.6.2

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Files changed (28) hide show
  1. package/README.md +9 -1
  2. package/dist/config/server-config.d.ts +15 -0
  3. package/dist/config/server-config.d.ts.map +1 -1
  4. package/dist/config/server-config.js +35 -0
  5. package/dist/config/server-config.js.map +1 -1
  6. package/dist/index.js +20 -1
  7. package/dist/index.js.map +1 -1
  8. package/dist/mcp-server/tools/definitions/get-study-results.tool.d.ts +4 -1
  9. package/dist/mcp-server/tools/definitions/get-study-results.tool.d.ts.map +1 -1
  10. package/dist/mcp-server/tools/definitions/get-study-results.tool.js +70 -4
  11. package/dist/mcp-server/tools/definitions/get-study-results.tool.js.map +1 -1
  12. package/dist/services/clinical-trials/clinical-trials-service.d.ts +19 -0
  13. package/dist/services/clinical-trials/clinical-trials-service.d.ts.map +1 -1
  14. package/dist/services/clinical-trials/clinical-trials-service.js +226 -1
  15. package/dist/services/clinical-trials/clinical-trials-service.js.map +1 -1
  16. package/dist/services/clinical-trials/mirror/index.d.ts +31 -0
  17. package/dist/services/clinical-trials/mirror/index.d.ts.map +1 -0
  18. package/dist/services/clinical-trials/mirror/index.js +66 -0
  19. package/dist/services/clinical-trials/mirror/index.js.map +1 -0
  20. package/dist/services/clinical-trials/mirror/ingester.d.ts +39 -0
  21. package/dist/services/clinical-trials/mirror/ingester.d.ts.map +1 -0
  22. package/dist/services/clinical-trials/mirror/ingester.js +308 -0
  23. package/dist/services/clinical-trials/mirror/ingester.js.map +1 -0
  24. package/dist/services/clinical-trials/mirror/types.d.ts +68 -0
  25. package/dist/services/clinical-trials/mirror/types.d.ts.map +1 -0
  26. package/dist/services/clinical-trials/mirror/types.js +45 -0
  27. package/dist/services/clinical-trials/mirror/types.js.map +1 -0
  28. package/package.json +1 -1
package/README.md CHANGED
@@ -7,7 +7,7 @@
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  <div align="center">
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- [![npm](https://img.shields.io/npm/v/clinicaltrialsgov-mcp-server?style=flat-square&logo=npm&logoColor=white)](https://www.npmjs.com/package/clinicaltrialsgov-mcp-server) [![Docker](https://img.shields.io/badge/Docker-ghcr.io-2496ED?style=flat-square&logo=docker&logoColor=white)](https://github.com/users/cyanheads/packages/container/package/clinicaltrialsgov-mcp-server) [![Version](https://img.shields.io/badge/Version-2.6.0-blue.svg?style=flat-square)](./CHANGELOG.md) [![MCP SDK](https://img.shields.io/badge/MCP%20SDK-^1.29.0-green.svg?style=flat-square)](https://modelcontextprotocol.io/) [![License](https://img.shields.io/badge/License-Apache%202.0-orange.svg?style=flat-square)](./LICENSE) [![TypeScript](https://img.shields.io/badge/TypeScript-^6.0-3178C6.svg?style=flat-square)](https://www.typescriptlang.org/) [![Bun](https://img.shields.io/badge/Bun-v1.3.2-blueviolet.svg?style=flat-square)](https://bun.sh/)
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+ [![npm](https://img.shields.io/npm/v/clinicaltrialsgov-mcp-server?style=flat-square&logo=npm&logoColor=white)](https://www.npmjs.com/package/clinicaltrialsgov-mcp-server) [![Docker](https://img.shields.io/badge/Docker-ghcr.io-2496ED?style=flat-square&logo=docker&logoColor=white)](https://github.com/users/cyanheads/packages/container/package/clinicaltrialsgov-mcp-server) [![Version](https://img.shields.io/badge/Version-2.6.2-blue.svg?style=flat-square)](./CHANGELOG.md) [![MCP SDK](https://img.shields.io/badge/MCP%20SDK-^1.29.0-green.svg?style=flat-square)](https://modelcontextprotocol.io/) [![License](https://img.shields.io/badge/License-Apache%202.0-orange.svg?style=flat-square)](./LICENSE) [![TypeScript](https://img.shields.io/badge/TypeScript-^6.0-3178C6.svg?style=flat-square)](https://www.typescriptlang.org/) [![Bun](https://img.shields.io/badge/Bun-v1.3.2-blueviolet.svg?style=flat-square)](https://bun.sh/)
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  </div>
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@@ -177,6 +177,10 @@ All configuration is optional — the server works with defaults and no API keys
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  | `CT_API_BASE_URL` | ClinicalTrials.gov API base URL. | `https://clinicaltrials.gov/api/v2` |
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  | `CT_REQUEST_TIMEOUT_MS` | Per-request timeout in milliseconds. | `30000` |
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  | `CT_MAX_PAGE_SIZE` | Maximum page size cap. | `200` |
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+ | `CT_MIRROR_ENABLED` | Enable the local SQLite study mirror. | `false` |
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+ | `CT_MIRROR_PATH` | Filesystem path for the mirror database. | `./clinical-trials-mirror.db` |
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+ | `CT_MIRROR_REFRESH_CRON` | Cron schedule for incremental mirror sync. | `0 3 * * *` (3 AM daily) |
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+ | `CT_MIRROR_FALLBACK_LIVE` | Fall back to live API when mirror is not yet bootstrapped. | `true` |
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  | `MCP_TRANSPORT_TYPE` | Transport: `stdio` or `http`. | `stdio` |
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  | `MCP_HTTP_PORT` | Port for HTTP server. | `3010` |
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  | `MCP_AUTH_MODE` | Auth mode: `none`, `jwt`, or `oauth`. | `none` |
@@ -184,6 +188,10 @@ All configuration is optional — the server works with defaults and no API keys
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  | `LOGS_DIR` | Directory for log files (Node.js only). | `<project-root>/logs` |
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  | `OTEL_ENABLED` | Enable OpenTelemetry tracing. | `false` |
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+ ### Local study mirror (opt-in)
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+
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+ Setting `CT_MIRROR_ENABLED=true` activates a self-refreshing SQLite+FTS5 local mirror of the ~577K-study corpus. Search and count queries route to the mirror first, with transparent fallback to the live API when the mirror is not yet ready (`CT_MIRROR_FALLBACK_LIVE=true`, the default). The mirror must be bootstrapped out-of-band before it becomes ready — while enabled but not yet bootstrapped it falls through to the live API identically to the disabled state. Once bootstrapped, the mirror eliminates live-API round-trips for most search and lookup operations. Full-record lookups (`clinicaltrials_get_study_record`), results data, field definitions, and field values remain live-API only.
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+
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  ## Running the Server
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  ### Local Development
package/dist/config/server-config.d.ts CHANGED
@@ -8,8 +8,23 @@ declare const ServerConfigSchema: z.ZodObject<{
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  requestTimeoutMs: z.ZodDefault<z.ZodCoercedNumber<unknown>>;
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  maxPageSize: z.ZodDefault<z.ZodCoercedNumber<unknown>>;
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  }, z.core.$strip>;
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+ /** Mirror-specific configuration parsed separately from the flat env var set. */
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+ declare const MirrorConfigSchema: z.ZodObject<{
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+ enabled: z.ZodDefault<z.ZodCoercedBoolean<unknown>>;
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+ path: z.ZodDefault<z.ZodString>;
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+ refreshCron: z.ZodDefault<z.ZodString>;
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+ fallbackLive: z.ZodDefault<z.ZodCoercedBoolean<unknown>>;
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+ }, z.core.$strip>;
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  export type ServerConfig = z.infer<typeof ServerConfigSchema>;
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+ export type MirrorConfig = z.infer<typeof MirrorConfigSchema> & {
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+ /** API base URL forwarded from the main config for the mirror ingester. */
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+ apiBaseUrl: string;
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+ /** Per-request timeout forwarded from the main config for the mirror ingester. */
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+ requestTimeoutMs: number;
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+ };
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  /** Get server configuration (lazy-parsed from env vars). */
13
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  export declare function getServerConfig(): ServerConfig;
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+ /** Get mirror configuration (lazy-parsed from env vars). */
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+ export declare function getMirrorConfig(): MirrorConfig;
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  export {};
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  //# sourceMappingURL=server-config.d.ts.map
package/dist/config/server-config.d.ts.map CHANGED
@@ -1 +1 @@
1
- {"version":3,"file":"server-config.d.ts","sourceRoot":"","sources":["../../src/config/server-config.ts"],"names":[],"mappings":"AAAA;;;GAGG;AAEH,OAAO,EAAE,CAAC,EAAE,MAAM,wBAAwB,CAAC;AAG3C,QAAA,MAAM,kBAAkB;;;;iBAOtB,CAAC;AAEH,MAAM,MAAM,YAAY,GAAG,CAAC,CAAC,KAAK,CAAC,OAAO,kBAAkB,CAAC,CAAC;AAI9D,4DAA4D;AAC5D,wBAAgB,eAAe,IAAI,YAAY,CAO9C"}
1
+ {"version":3,"file":"server-config.d.ts","sourceRoot":"","sources":["../../src/config/server-config.ts"],"names":[],"mappings":"AAAA;;;GAGG;AAEH,OAAO,EAAE,CAAC,EAAE,MAAM,wBAAwB,CAAC;AAG3C,QAAA,MAAM,kBAAkB;;;;iBAOtB,CAAC;AAEH,iFAAiF;AACjF,QAAA,MAAM,kBAAkB;;;;;iBActB,CAAC;AAEH,MAAM,MAAM,YAAY,GAAG,CAAC,CAAC,KAAK,CAAC,OAAO,kBAAkB,CAAC,CAAC;AAC9D,MAAM,MAAM,YAAY,GAAG,CAAC,CAAC,KAAK,CAAC,OAAO,kBAAkB,CAAC,GAAG;IAC9D,2EAA2E;IAC3E,UAAU,EAAE,MAAM,CAAC;IACnB,kFAAkF;IAClF,gBAAgB,EAAE,MAAM,CAAC;CAC1B,CAAC;AAKF,4DAA4D;AAC5D,wBAAgB,eAAe,IAAI,YAAY,CAO9C;AAED,4DAA4D;AAC5D,wBAAgB,eAAe,IAAI,YAAY,CAgB9C"}
package/dist/config/server-config.js CHANGED
@@ -12,7 +12,24 @@ const ServerConfigSchema = z.object({
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  requestTimeoutMs: z.coerce.number().default(30_000).describe('Per-request timeout in ms'),
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  maxPageSize: z.coerce.number().default(200).describe('Maximum page size cap'),
14
14
  });
15
+ /** Mirror-specific configuration parsed separately from the flat env var set. */
16
+ const MirrorConfigSchema = z.object({
17
+ enabled: z.coerce.boolean().default(false).describe('Enable the local SQLite study mirror'),
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+ path: z
19
+ .string()
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+ .default('./clinical-trials-mirror.db')
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+ .describe('Filesystem path for the mirror SQLite database'),
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+ refreshCron: z
23
+ .string()
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+ .default('0 3 * * *')
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+ .describe('Cron expression for incremental mirror refresh (default: 3 AM daily)'),
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+ fallbackLive: z.coerce
27
+ .boolean()
28
+ .default(true)
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+ .describe('Fall back to live API when mirror is not ready'),
30
+ });
15
31
  let _config;
32
+ let _mirrorConfig;
16
33
  /** Get server configuration (lazy-parsed from env vars). */
17
34
  export function getServerConfig() {
18
35
  _config ??= parseEnvConfig(ServerConfigSchema, {
@@ -22,4 +39,22 @@ export function getServerConfig() {
22
39
  });
23
40
  return _config;
24
41
  }
42
+ /** Get mirror configuration (lazy-parsed from env vars). */
43
+ export function getMirrorConfig() {
44
+ if (!_mirrorConfig) {
45
+ const base = parseEnvConfig(MirrorConfigSchema, {
46
+ enabled: 'CT_MIRROR_ENABLED',
47
+ path: 'CT_MIRROR_PATH',
48
+ refreshCron: 'CT_MIRROR_REFRESH_CRON',
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+ fallbackLive: 'CT_MIRROR_FALLBACK_LIVE',
50
+ });
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+ const server = getServerConfig();
52
+ _mirrorConfig = {
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+ ...base,
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+ apiBaseUrl: server.apiBaseUrl,
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+ requestTimeoutMs: server.requestTimeoutMs,
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+ };
57
+ }
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+ return _mirrorConfig;
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+ }
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  //# sourceMappingURL=server-config.js.map
package/dist/config/server-config.js.map CHANGED
@@ -1 +1 @@
1
- {"version":3,"file":"server-config.js","sourceRoot":"","sources":["../../src/config/server-config.ts"],"names":[],"mappings":"AAAA;;;GAGG;AAEH,OAAO,EAAE,CAAC,EAAE,MAAM,wBAAwB,CAAC;AAC3C,OAAO,EAAE,cAAc,EAAE,MAAM,+BAA+B,CAAC;AAE/D,MAAM,kBAAkB,GAAG,CAAC,CAAC,MAAM,CAAC;IAClC,UAAU,EAAE,CAAC;SACV,MAAM,EAAE;SACR,OAAO,CAAC,mCAAmC,CAAC;SAC5C,QAAQ,CAAC,iCAAiC,CAAC;IAC9C,gBAAgB,EAAE,CAAC,CAAC,MAAM,CAAC,MAAM,EAAE,CAAC,OAAO,CAAC,MAAM,CAAC,CAAC,QAAQ,CAAC,2BAA2B,CAAC;IACzF,WAAW,EAAE,CAAC,CAAC,MAAM,CAAC,MAAM,EAAE,CAAC,OAAO,CAAC,GAAG,CAAC,CAAC,QAAQ,CAAC,uBAAuB,CAAC;CAC9E,CAAC,CAAC;AAIH,IAAI,OAAiC,CAAC;AAEtC,4DAA4D;AAC5D,MAAM,UAAU,eAAe;IAC7B,OAAO,KAAK,cAAc,CAAC,kBAAkB,EAAE;QAC7C,UAAU,EAAE,iBAAiB;QAC7B,gBAAgB,EAAE,uBAAuB;QACzC,WAAW,EAAE,kBAAkB;KAChC,CAAC,CAAC;IACH,OAAO,OAAO,CAAC;AACjB,CAAC"}
1
+ {"version":3,"file":"server-config.js","sourceRoot":"","sources":["../../src/config/server-config.ts"],"names":[],"mappings":"AAAA;;;GAGG;AAEH,OAAO,EAAE,CAAC,EAAE,MAAM,wBAAwB,CAAC;AAC3C,OAAO,EAAE,cAAc,EAAE,MAAM,+BAA+B,CAAC;AAE/D,MAAM,kBAAkB,GAAG,CAAC,CAAC,MAAM,CAAC;IAClC,UAAU,EAAE,CAAC;SACV,MAAM,EAAE;SACR,OAAO,CAAC,mCAAmC,CAAC;SAC5C,QAAQ,CAAC,iCAAiC,CAAC;IAC9C,gBAAgB,EAAE,CAAC,CAAC,MAAM,CAAC,MAAM,EAAE,CAAC,OAAO,CAAC,MAAM,CAAC,CAAC,QAAQ,CAAC,2BAA2B,CAAC;IACzF,WAAW,EAAE,CAAC,CAAC,MAAM,CAAC,MAAM,EAAE,CAAC,OAAO,CAAC,GAAG,CAAC,CAAC,QAAQ,CAAC,uBAAuB,CAAC;CAC9E,CAAC,CAAC;AAEH,iFAAiF;AACjF,MAAM,kBAAkB,GAAG,CAAC,CAAC,MAAM,CAAC;IAClC,OAAO,EAAE,CAAC,CAAC,MAAM,CAAC,OAAO,EAAE,CAAC,OAAO,CAAC,KAAK,CAAC,CAAC,QAAQ,CAAC,sCAAsC,CAAC;IAC3F,IAAI,EAAE,CAAC;SACJ,MAAM,EAAE;SACR,OAAO,CAAC,6BAA6B,CAAC;SACtC,QAAQ,CAAC,gDAAgD,CAAC;IAC7D,WAAW,EAAE,CAAC;SACX,MAAM,EAAE;SACR,OAAO,CAAC,WAAW,CAAC;SACpB,QAAQ,CAAC,sEAAsE,CAAC;IACnF,YAAY,EAAE,CAAC,CAAC,MAAM;SACnB,OAAO,EAAE;SACT,OAAO,CAAC,IAAI,CAAC;SACb,QAAQ,CAAC,gDAAgD,CAAC;CAC9D,CAAC,CAAC;AAUH,IAAI,OAAiC,CAAC;AACtC,IAAI,aAAuC,CAAC;AAE5C,4DAA4D;AAC5D,MAAM,UAAU,eAAe;IAC7B,OAAO,KAAK,cAAc,CAAC,kBAAkB,EAAE;QAC7C,UAAU,EAAE,iBAAiB;QAC7B,gBAAgB,EAAE,uBAAuB;QACzC,WAAW,EAAE,kBAAkB;KAChC,CAAC,CAAC;IACH,OAAO,OAAO,CAAC;AACjB,CAAC;AAED,4DAA4D;AAC5D,MAAM,UAAU,eAAe;IAC7B,IAAI,CAAC,aAAa,EAAE,CAAC;QACnB,MAAM,IAAI,GAAG,cAAc,CAAC,kBAAkB,EAAE;YAC9C,OAAO,EAAE,mBAAmB;YAC5B,IAAI,EAAE,gBAAgB;YACtB,WAAW,EAAE,wBAAwB;YACrC,YAAY,EAAE,yBAAyB;SACxC,CAAC,CAAC;QACH,MAAM,MAAM,GAAG,eAAe,EAAE,CAAC;QACjC,aAAa,GAAG;YACd,GAAG,IAAI;YACP,UAAU,EAAE,MAAM,CAAC,UAAU;YAC7B,gBAAgB,EAAE,MAAM,CAAC,gBAAgB;SAC1C,CAAC;IACJ,CAAC;IACD,OAAO,aAAa,CAAC;AACvB,CAAC"}
package/dist/index.js CHANGED
@@ -4,10 +4,13 @@
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  * @module index
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  */
6
6
  import { createApp } from '@cyanheads/mcp-ts-core';
7
+ import { schedulerService } from '@cyanheads/mcp-ts-core/utils';
8
+ import { getMirrorConfig } from './config/server-config.js';
7
9
  import { allPromptDefinitions } from './mcp-server/prompts/definitions/index.js';
8
10
  import { allResourceDefinitions } from './mcp-server/resources/definitions/index.js';
9
11
  import { allToolDefinitions } from './mcp-server/tools/definitions/index.js';
10
12
  import { initClinicalTrialsService } from './services/clinical-trials/clinical-trials-service.js';
13
+ import { getClinicalTrialsMirror, initMirror } from './services/clinical-trials/mirror/index.js';
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14
  await createApp({
12
15
  tools: allToolDefinitions,
13
16
  resources: allResourceDefinitions,
@@ -16,8 +19,24 @@ await createApp({
16
19
  landing: {
17
20
  requireAuth: false,
18
21
  },
19
- setup() {
22
+ async setup({ config }) {
20
23
  initClinicalTrialsService();
24
+ const mirrorConfig = getMirrorConfig();
25
+ if (mirrorConfig.enabled) {
26
+ initMirror(mirrorConfig);
27
+ // Schedule incremental refresh on HTTP transport only — stdio operators
28
+ // run the server per-request and don't benefit from a persistent cron.
29
+ // The full init must be run out-of-band (bootstrap script, CLI, or manual runSync).
30
+ if (config.mcpTransportType === 'http') {
31
+ const mirror = getClinicalTrialsMirror();
32
+ if (mirror) {
33
+ await schedulerService.schedule('ct-mirror-refresh', mirrorConfig.refreshCron, async (_ctx) => {
34
+ await mirror.runSync({ mode: 'refresh' });
35
+ }, 'Incremental ClinicalTrials.gov mirror refresh');
36
+ schedulerService.start('ct-mirror-refresh');
37
+ }
38
+ }
39
+ }
21
40
  },
22
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  });
23
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  //# sourceMappingURL=index.js.map
package/dist/index.js.map CHANGED
@@ -1 +1 @@
1
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package/dist/mcp-server/tools/definitions/get-study-results.tool.d.ts CHANGED
@@ -1,5 +1,5 @@
1
1
  /**
2
- * @fileoverview Extract outcomes, adverse events, participant flow, and baseline from completed studies.
2
+ * @fileoverview Extract outcomes, adverse events, participant flow, baseline, and results metadata from completed studies.
3
3
  * @module mcp-server/tools/definitions/get-study-results.tool
4
4
  */
5
5
  import { z } from '@cyanheads/mcp-ts-core';
@@ -11,11 +11,13 @@ export declare const getStudyResults: import("@cyanheads/mcp-ts-core").ToolDefin
11
11
  adverseEvents: "adverseEvents";
12
12
  participantFlow: "participantFlow";
13
13
  baseline: "baseline";
14
+ moreInfo: "moreInfo";
14
15
  }>, z.ZodArray<z.ZodEnum<{
15
16
  outcomes: "outcomes";
16
17
  adverseEvents: "adverseEvents";
17
18
  participantFlow: "participantFlow";
18
19
  baseline: "baseline";
20
+ moreInfo: "moreInfo";
19
21
  }>>]>>;
20
22
  summary: z.ZodDefault<z.ZodBoolean>;
21
23
  }, z.core.$strip>, z.ZodObject<{
@@ -27,6 +29,7 @@ export declare const getStudyResults: import("@cyanheads/mcp-ts-core").ToolDefin
27
29
  adverseEvents: z.ZodOptional<z.ZodRecord<z.ZodString, z.ZodUnknown>>;
28
30
  participantFlow: z.ZodOptional<z.ZodRecord<z.ZodString, z.ZodUnknown>>;
29
31
  baseline: z.ZodOptional<z.ZodRecord<z.ZodString, z.ZodUnknown>>;
32
+ moreInfo: z.ZodOptional<z.ZodRecord<z.ZodString, z.ZodUnknown>>;
30
33
  }, z.core.$strip>>;
31
34
  studiesWithoutResults: z.ZodOptional<z.ZodArray<z.ZodString>>;
32
35
  fetchErrors: z.ZodOptional<z.ZodArray<z.ZodObject<{
package/dist/mcp-server/tools/definitions/get-study-results.tool.d.ts.map CHANGED
@@ -1 +1 @@
1
- {"version":3,"file":"get-study-results.tool.d.ts","sourceRoot":"","sources":["../../../../src/mcp-server/tools/definitions/get-study-results.tool.ts"],"names":[],"mappings":"AAAA;;;GAGG;AAEH,OAAO,EAAQ,CAAC,EAAE,MAAM,wBAAwB,CAAC;AACjD,OAAO,EAAE,gBAAgB,EAAE,MAAM,+BAA+B,CAAC;AA+YjE,eAAO,MAAM,eAAe;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;cA2O1B,CAAC"}
1
+ {"version":3,"file":"get-study-results.tool.d.ts","sourceRoot":"","sources":["../../../../src/mcp-server/tools/definitions/get-study-results.tool.ts"],"names":[],"mappings":"AAAA;;;GAGG;AAEH,OAAO,EAAQ,CAAC,EAAE,MAAM,wBAAwB,CAAC;AACjD,OAAO,EAAE,gBAAgB,EAAE,MAAM,+BAA+B,CAAC;AAucjE,eAAO,MAAM,eAAe;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;cAoP1B,CAAC"}
package/dist/mcp-server/tools/definitions/get-study-results.tool.js CHANGED
@@ -1,5 +1,5 @@
1
1
  /**
2
- * @fileoverview Extract outcomes, adverse events, participant flow, and baseline from completed studies.
2
+ * @fileoverview Extract outcomes, adverse events, participant flow, baseline, and results metadata from completed studies.
3
3
  * @module mcp-server/tools/definitions/get-study-results.tool
4
4
  */
5
5
  import { tool, z } from '@cyanheads/mcp-ts-core';
@@ -7,13 +7,20 @@ import { JsonRpcErrorCode } from '@cyanheads/mcp-ts-core/errors';
7
7
  import { getClinicalTrialsService } from '../../../services/clinical-trials/clinical-trials-service.js';
8
8
  import { nctIdSchema } from '../utils/_schemas.js';
9
9
  import { RECOVERY_HINTS } from '../utils/recovery-hints.js';
10
- const VALID_SECTIONS = ['outcomes', 'adverseEvents', 'participantFlow', 'baseline'];
10
+ const VALID_SECTIONS = [
11
+ 'outcomes',
12
+ 'adverseEvents',
13
+ 'participantFlow',
14
+ 'baseline',
15
+ 'moreInfo',
16
+ ];
11
17
  /** Map section names to resultsSection module keys. */
12
18
  const SECTION_MAP = {
13
19
  outcomes: 'outcomeMeasuresModule',
14
20
  adverseEvents: 'adverseEventsModule',
15
21
  participantFlow: 'participantFlowModule',
16
22
  baseline: 'baselineCharacteristicsModule',
23
+ moreInfo: 'moreInfoModule',
17
24
  };
18
25
  /**
19
26
  * Extract top-line per-group stats from a raw outcome object (full mode).
@@ -156,6 +163,26 @@ function summarizeBaseline(bl) {
156
163
  : undefined,
157
164
  };
158
165
  }
166
+ /**
167
+ * Condense the more-info module — keep the small metadata (limitations, contact,
168
+ * agreement flags) and drop only the verbose `certainAgreement.otherDetails` prose.
169
+ */
170
+ function summarizeMoreInfo(mi) {
171
+ const agreement = mi.certainAgreement;
172
+ return {
173
+ ...(mi.limitationsAndCaveats ? { limitationsAndCaveats: mi.limitationsAndCaveats } : {}),
174
+ ...(agreement
175
+ ? {
176
+ certainAgreement: {
177
+ piSponsorEmployee: agreement.piSponsorEmployee,
178
+ restrictiveAgreement: agreement.restrictiveAgreement,
179
+ restrictionType: agreement.restrictionType,
180
+ },
181
+ }
182
+ : {}),
183
+ ...(mi.pointOfContact ? { pointOfContact: mi.pointOfContact } : {}),
184
+ };
185
+ }
159
186
  /** Build a groupId→title lookup from a groups array. */
160
187
  function groupMap(obj) {
161
188
  const groups = (obj.groups ?? obj.eventGroups);
@@ -357,8 +384,39 @@ function formatBaseline(bl, lines) {
357
384
  }
358
385
  }
359
386
  }
387
+ function formatMoreInfo(mi, lines) {
388
+ // Header is unconditional, matching the sibling section renderers — keeps the
389
+ // section visible on the content[] channel for format-parity, whose synthetic
390
+ // sample for an opaque record carries none of the named sub-keys below.
391
+ lines.push('\n### More Info');
392
+ const lim = mi.limitationsAndCaveats;
393
+ const agr = mi.certainAgreement;
394
+ const poc = mi.pointOfContact;
395
+ if (lim?.description)
396
+ lines.push(`**Limitations & Caveats:** ${lim.description}`);
397
+ if (agr) {
398
+ const parts = [
399
+ agr.restrictiveAgreement != null
400
+ ? `Restrictive agreement: ${agr.restrictiveAgreement ? 'yes' : 'no'}`
401
+ : '',
402
+ agr.restrictionType ? `Type: ${agr.restrictionType}` : '',
403
+ agr.piSponsorEmployee != null
404
+ ? `PI is sponsor employee: ${agr.piSponsorEmployee ? 'yes' : 'no'}`
405
+ : '',
406
+ ].filter(Boolean);
407
+ if (parts.length)
408
+ lines.push(`**Certain Agreement:** ${parts.join(' | ')}`);
409
+ if (agr.otherDetails)
410
+ lines.push(` ${agr.otherDetails}`);
411
+ }
412
+ if (poc) {
413
+ const parts = [poc.title, poc.organization, poc.email, poc.phone].filter(Boolean);
414
+ if (parts.length)
415
+ lines.push(`**Point of Contact:** ${parts.join(' | ')}`);
416
+ }
417
+ }
360
418
  export const getStudyResults = tool('clinicaltrials_get_study_results', {
361
- description: `Fetch clinical trial results data from ClinicalTrials.gov for completed studies — outcome measures with statistics, adverse events, participant flow, and baseline characteristics. Only available for studies where hasResults is true. Use clinicaltrials_search_studies first to find studies with results.`,
419
+ description: `Fetch clinical trial results data from ClinicalTrials.gov for completed studies — outcome measures with statistics, adverse events, participant flow, baseline characteristics, and results metadata (limitations & caveats, certain-agreement disclosure restrictions, results point of contact). Only available for studies where hasResults is true. Use clinicaltrials_search_studies first to find studies with results.`,
362
420
  annotations: {
363
421
  readOnlyHint: true,
364
422
  idempotentHint: true,
@@ -392,7 +450,7 @@ export const getStudyResults = tool('clinicaltrials_get_study_results', {
392
450
  z.array(z.enum(VALID_SECTIONS)).describe('Multiple section names.'),
393
451
  ])
394
452
  .optional()
395
- .describe(`Filter which sections to return. Values: outcomes, adverseEvents, participantFlow, baseline. Omit for all sections.`),
453
+ .describe(`Filter which sections to return. Values: outcomes, adverseEvents, participantFlow, baseline, moreInfo. Omit for all sections.`),
396
454
  summary: z
397
455
  .boolean()
398
456
  .default(false)
@@ -421,6 +479,10 @@ export const getStudyResults = tool('clinicaltrials_get_study_results', {
421
479
  .record(z.string(), z.unknown())
422
480
  .optional()
423
481
  .describe('Baseline characteristics. Summary mode: groupCount, measureCount, and measures (title, paramType, unitOfMeasure). Full mode: adds groups and measures with per-group classes/categories/measurements.'),
482
+ moreInfo: z
483
+ .record(z.string(), z.unknown())
484
+ .optional()
485
+ .describe('Results metadata from moreInfoModule. Summary mode: limitationsAndCaveats, certainAgreement flags (piSponsorEmployee, restrictiveAgreement, restrictionType), and pointOfContact. Full mode: adds certainAgreement.otherDetails.'),
424
486
  })
425
487
  .describe('Extracted results for one study.'))
426
488
  .describe('Results per study.'),
@@ -511,6 +573,8 @@ export const getStudyResults = tool('clinicaltrials_get_study_results', {
511
573
  entry.participantFlow = summarizeParticipantFlow(data);
512
574
  else if (section === 'baseline')
513
575
  entry.baseline = summarizeBaseline(data);
576
+ else if (section === 'moreInfo')
577
+ entry.moreInfo = summarizeMoreInfo(data);
514
578
  }
515
579
  else {
516
580
  entry[section] = data;
@@ -546,6 +610,8 @@ export const getStudyResults = tool('clinicaltrials_get_study_results', {
546
610
  formatParticipantFlow(r.participantFlow, lines);
547
611
  if (r.baseline)
548
612
  formatBaseline(r.baseline, lines);
613
+ if (r.moreInfo)
614
+ formatMoreInfo(r.moreInfo, lines);
549
615
  lines.push('');
550
616
  }
551
617
  if (result.studiesWithoutResults?.length)
package/dist/mcp-server/tools/definitions/get-study-results.tool.js.map CHANGED
@@ -1 +1 @@
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package/dist/services/clinical-trials/clinical-trials-service.d.ts CHANGED
@@ -1,8 +1,12 @@
1
1
  /**
2
2
  * @fileoverview ClinicalTrials.gov REST API v2 client with retry, rate limiting, and timeout.
3
+ * Routes search and count operations to the local mirror when enabled and ready,
4
+ * falling back to the live API when the mirror is unavailable or the query requires
5
+ * features the mirror cannot answer (geo filters, complex AREA[] expressions).
3
6
  * @module services/clinical-trials/clinical-trials-service
4
7
  */
5
8
  import type { Context } from '@cyanheads/mcp-ts-core';
9
+ import type { MirrorStatus } from '@cyanheads/mcp-ts-core/mirror';
6
10
  import { type ServerConfig } from '../../config/server-config.js';
7
11
  import { type FieldIndexEntry } from './field-search.js';
8
12
  import type { FieldNode, FieldValueStats, PagedStudiesResponse, SearchParams, Study } from './types.js';
@@ -35,12 +39,27 @@ export declare class ClinicalTrialsService {
35
39
  getStudy(nctId: string, ctx: Context): Promise<Study>;
36
40
  /** Fetch multiple studies by NCT IDs in a single request. Returns identification and results section data. */
37
41
  getStudiesBatch(nctIds: string[], ctx: Context): Promise<Study[]>;
42
+ /**
43
+ * Return current mirror status, or `undefined` when the mirror is disabled.
44
+ * Exposed so tools can surface mirror state to agents when useful.
45
+ */
46
+ mirrorStatus(): Promise<MirrorStatus | undefined>;
38
47
  /** Get field definitions (metadata tree) from the data model. */
39
48
  getMetadata(includeIndexedOnly: boolean, ctx: Context): Promise<FieldNode[]>;
40
49
  /** Get field value statistics for the specified fields. */
41
50
  getFieldValues(fields: string[], ctx: Context): Promise<FieldValueStats[]>;
42
51
  /** Search the field model by keyword, returning ranked matches with paths and types. */
43
52
  searchFieldDefinitions(query: string, limit: number, ctx: Context): Promise<FieldIndexEntry[]>;
53
+ /**
54
+ * Attempt to serve a `searchStudies` call from the local mirror.
55
+ *
56
+ * Returns `null` when the mirror is not ready, or when the query uses
57
+ * features the mirror cannot answer (geo filters, complex AREA[] advanced
58
+ * filters, field selection beyond the metadata tier, or pageToken
59
+ * continuation from a previous live-API page). In all of those cases the
60
+ * caller falls through to the live API.
61
+ */
62
+ private tryMirrorSearch;
44
63
  /** Lazy-load and memoize the flattened field index from /studies/metadata. */
45
64
  private getFieldIndex;
46
65
  /**
package/dist/services/clinical-trials/clinical-trials-service.d.ts.map CHANGED
@@ -1 +1 @@
1
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