@teselagen/sequence-utils 0.1.6 → 0.1.8

package/index.js

@@ -1,57 +1,8 @@
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p},n.prototype.diff_commonOverlap_=function(i,c){var g=i.length,l=c.length;if(g==0||l==0)return 0;g>l?i=i.substring(g-l):g<l&&(c=c.substring(0,g));var p=Math.min(g,l);if(i==c)return p;for(var I=0,h=1;;){var v=i.substring(p-h),m=c.indexOf(v);if(m==-1)return I;h+=m,(m==0||i.substring(p-h)==c.substring(0,h))&&(I=h,h++)}},n.prototype.diff_halfMatch_=function(i,c){if(this.Diff_Timeout<=0)return null;var g=i.length>c.length?i:c,l=i.length>c.length?c:i;if(g.length<4||l.length*2<g.length)return null;var p=this;function I(F,N,_){for(var U=F.substring(_,_+Math.floor(F.length/4)),L=-1,W="",z,de,ie,fe;(L=N.indexOf(U,L+1))!=-1;){var Be=p.diff_commonPrefix(F.substring(_),N.substring(L)),$e=p.diff_commonSuffix(F.substring(0,_),N.substring(0,L));W.length<$e+Be&&(W=N.substring(L-$e,L)+N.substring(L,L+Be),z=F.substring(0,_-$e),de=F.substring(_+Be),ie=N.substring(0,L-$e),fe=N.substring(L+Be))}return W.length*2>=F.length?[z,de,ie,fe,W]:null}var h=I(g,l,Math.ceil(g.length/4)),v=I(g,l,Math.ceil(g.length/2)),m;if(!h&&!v)return null;v?h?m=h[4].length>v[4].length?h:v:m=v:m=h;var w,B,x,C;i.length>c.length?(w=m[0],B=m[1],x=m[2],C=m[3]):(x=m[0],C=m[1],w=m[2],B=m[3]);var H=m[4];return[w,B,x,C,H]},n.prototype.diff_cleanupSemantic=function(i){for(var c=!1,g=[],l=0,p=null,I=0,h=0,v=0,m=0,w=0;I<i.length;)i[I][0]==f?(g[l++]=I,h=m,v=w,m=0,w=0,p=i[I][1]):(i[I][0]==o?m+=i[I][1].length:w+=i[I][1].length,p&&p.length<=Math.max(h,v)&&p.length<=Math.max(m,w)&&(i.splice(g[l-1],0,new n.Diff(r,p)),i[g[l-1]+1][0]=o,l--,l--,I=l>0?g[l-1]:-1,h=0,v=0,m=0,w=0,p=null,c=!0)),I++;for(c&&this.diff_cleanupMerge(i),this.diff_cleanupSemanticLossless(i),I=1;I<i.length;){if(i[I-1][0]==r&&i[I][0]==o){var B=i[I-1][1],x=i[I][1],C=this.diff_commonOverlap_(B,x),H=this.diff_commonOverlap_(x,B);C>=H?(C>=B.length/2||C>=x.length/2)&&(i.splice(I,0,new n.Diff(f,x.substring(0,C))),i[I-1][1]=B.substring(0,B.length-C),i[I+1][1]=x.substring(C),I++):(H>=B.length/2||H>=x.length/2)&&(i.splice(I,0,new n.Diff(f,B.substring(0,H))),i[I-1][0]=o,i[I-1][1]=x.substring(0,x.length-H),i[I+1][0]=r,i[I+1][1]=B.substring(H),I++),I++}I++}},n.prototype.diff_cleanupSemanticLossless=function(i){function c(H,F){if(!H||!F)return 6;var N=H.charAt(H.length-1),_=F.charAt(0),U=N.match(n.nonAlphaNumericRegex_),L=_.match(n.nonAlphaNumericRegex_),W=U&&N.match(n.whitespaceRegex_),z=L&&_.match(n.whitespaceRegex_),de=W&&N.match(n.linebreakRegex_),ie=z&&_.match(n.linebreakRegex_),fe=de&&H.match(n.blanklineEndRegex_),Be=ie&&F.match(n.blanklineStartRegex_);return fe||Be?5:de||ie?4:U&&!W&&z?3:W||z?2:U||L?1:0}for(var g=1;g<i.length-1;){if(i[g-1][0]==f&&i[g+1][0]==f){var l=i[g-1][1],p=i[g][1],I=i[g+1][1],h=this.diff_commonSuffix(l,p);if(h){var v=p.substring(p.length-h);l=l.substring(0,l.length-h),p=v+p.substring(0,p.length-h),I=v+I}for(var m=l,w=p,B=I,x=c(l,p)+c(p,I);p.charAt(0)===I.charAt(0);){l+=p.charAt(0),p=p.substring(1)+I.charAt(0),I=I.substring(1);var C=c(l,p)+c(p,I);C>=x&&(x=C,m=l,w=p,B=I)}i[g-1][1]!=m&&(m?i[g-1][1]=m:(i.splice(g-1,1),g--),i[g][1]=w,B?i[g+1][1]=B:(i.splice(g+1,1),g--))}g++}},n.nonAlphaNumericRegex_=/[^a-zA-Z0-9]/,n.whitespaceRegex_=/\s/,n.linebreakRegex_=/[\r\n]/,n.blanklineEndRegex_=/\n\r?\n$/,n.blanklineStartRegex_=/^\r?\n\r?\n/,n.prototype.diff_cleanupEfficiency=function(i){for(var c=!1,g=[],l=0,p=null,I=0,h=!1,v=!1,m=!1,w=!1;I<i.length;)i[I][0]==f?(i[I][1].length<this.Diff_EditCost&&(m||w)?(g[l++]=I,h=m,v=w,p=i[I][1]):(l=0,p=null),m=w=!1):(i[I][0]==r?w=!0:m=!0,p&&(h&&v&&m&&w||p.length<this.Diff_EditCost/2&&h+v+m+w==3)&&(i.splice(g[l-1],0,new n.Diff(r,p)),i[g[l-1]+1][0]=o,l--,p=null,h&&v?(m=w=!0,l=0):(l--,I=l>0?g[l-1]:-1,m=w=!1),c=!0)),I++;c&&this.diff_cleanupMerge(i)},n.prototype.diff_cleanupMerge=function(i){i.push(new n.Diff(f,""));for(var c=0,g=0,l=0,p="",I="",h;c<i.length;)switch(i[c][0]){case o:l++,I+=i[c][1],c++;break;case r:g++,p+=i[c][1],c++;break;case f:g+l>1?(g!==0&&l!==0&&(h=this.diff_commonPrefix(I,p),h!==0&&(c-g-l>0&&i[c-g-l-1][0]==f?i[c-g-l-1][1]+=I.substring(0,h):(i.splice(0,0,new n.Diff(f,I.substring(0,h))),c++),I=I.substring(h),p=p.substring(h)),h=this.diff_commonSuffix(I,p),h!==0&&(i[c][1]=I.substring(I.length-h)+i[c][1],I=I.substring(0,I.length-h),p=p.substring(0,p.length-h))),c-=g+l,i.splice(c,g+l),p.length&&(i.splice(c,0,new n.Diff(r,p)),c++),I.length&&(i.splice(c,0,new n.Diff(o,I)),c++),c++):c!==0&&i[c-1][0]==f?(i[c-1][1]+=i[c][1],i.splice(c,1)):c++,l=0,g=0,p="",I="";break}i[i.length-1][1]===""&&i.pop();var v=!1;for(c=1;c<i.length-1;)i[c-1][0]==f&&i[c+1][0]==f&&(i[c][1].substring(i[c][1].length-i[c-1][1].length)==i[c-1][1]?(i[c][1]=i[c-1][1]+i[c][1].substring(0,i[c][1].length-i[c-1][1].length),i[c+1][1]=i[c-1][1]+i[c+1][1],i.splice(c-1,1),v=!0):i[c][1].substring(0,i[c+1][1].length)==i[c+1][1]&&(i[c-1][1]+=i[c+1][1],i[c][1]=i[c][1].substring(i[c+1][1].length)+i[c+1][1],i.splice(c+1,1),v=!0)),c++;v&&this.diff_cleanupMerge(i)},n.prototype.diff_xIndex=function(i,c){var g=0,l=0,p=0,I=0,h;for(h=0;h<i.length&&(i[h][0]!==o&&(g+=i[h][1].length),i[h][0]!==r&&(l+=i[h][1].length),!(g>c));h++)p=g,I=l;return i.length!=h&&i[h][0]===r?I:I+(c-p)},n.prototype.diff_prettyHtml=function(i){for(var c=[],g=/&/g,l=/</g,p=/>/g,I=/\n/g,h=0;h<i.length;h++){var v=i[h][0],m=i[h][1],w=m.replace(g,"&amp;").replace(l,"&lt;").replace(p,"&gt;").replace(I,"&para;<br>");switch(v){case o:c[h]='<ins style="background:#e6ffe6;">'+w+"</ins>";break;case r:c[h]='<del style="background:#ffe6e6;">'+w+"</del>";break;case f:c[h]="<span>"+w+"</span>";break}}return c.join("")},n.prototype.diff_text1=function(i){for(var c=[],g=0;g<i.length;g++)i[g][0]!==o&&(c[g]=i[g][1]);return c.join("")},n.prototype.diff_text2=function(i){for(var c=[],g=0;g<i.length;g++)i[g][0]!==r&&(c[g]=i[g][1]);return c.join("")},n.prototype.diff_levenshtein=function(i){for(var c=0,g=0,l=0,p=0;p<i.length;p++){var I=i[p][0],h=i[p][1];switch(I){case o:g+=h.length;break;case r:l+=h.length;break;case f:c+=Math.max(g,l),g=0,l=0;break}}return c+=Math.max(g,l),c},n.prototype.diff_toDelta=function(i){for(var c=[],g=0;g<i.length;g++)switch(i[g][0]){case o:c[g]="+"+encodeURI(i[g][1]);break;case r:c[g]="-"+i[g][1].length;break;case f:c[g]="="+i[g][1].length;break}return c.join("	").replace(/%20/g," ")},n.prototype.diff_fromDelta=function(i,c){for(var g=[],l=0,p=0,I=c.split(/\t/g),h=0;h<I.length;h++){var v=I[h].substring(1);switch(I[h].charAt(0)){case"+":try{g[l++]=new n.Diff(o,decodeURI(v))}catch(B){throw new Error("Illegal escape in diff_fromDelta: "+v)}break;case"-":case"=":var m=parseInt(v,10);if(isNaN(m)||m<0)throw new Error("Invalid number in diff_fromDelta: "+v);var w=i.substring(p,p+=m);I[h].charAt(0)=="="?g[l++]=new n.Diff(f,w):g[l++]=new n.Diff(r,w);break;default:if(I[h])throw new Error("Invalid diff operation in diff_fromDelta: "+I[h])}}if(p!=i.length)throw new Error("Delta length ("+p+") does not equal source text length ("+i.length+").");return g},n.prototype.match_main=function(i,c,g){if(i==null||c==null||g==null)throw new Error("Null input. (match_main)");return g=Math.max(0,Math.min(g,i.length)),i==c?0:i.length?i.substring(g,g+c.length)==c?g:this.match_bitap_(i,c,g):-1},n.prototype.match_bitap_=function(i,c,g){if(c.length>this.Match_MaxBits)throw new Error("Pattern too long for this browser.");var l=this.match_alphabet_(c),p=this;function I(z,de){var ie=z/c.length,fe=Math.abs(g-de);return p.Match_Distance?ie+fe/p.Match_Distance:fe?1:ie}var h=this.Match_Threshold,v=i.indexOf(c,g);v!=-1&&(h=Math.min(I(0,v),h),v=i.lastIndexOf(c,g+c.length),v!=-1&&(h=Math.min(I(0,v),h)));var m=1<<c.length-1;v=-1;for(var w,B,x=c.length+i.length,C,H=0;H<c.length;H++){for(w=0,B=x;w<B;)I(H,g+B)<=h?w=B:x=B,B=Math.floor((x-w)/2+w);x=B;var F=Math.max(1,g-B+1),N=Math.min(g+B,i.length)+c.length,_=Array(N+2);_[N+1]=(1<<H)-1;for(var U=N;U>=F;U--){var L=l[i.charAt(U-1)];if(H===0?_[U]=(_[U+1]<<1|1)&L:_[U]=(_[U+1]<<1|1)&L|((C[U+1]|C[U])<<1|1)|C[U+1],_[U]&m){var W=I(H,U-1);if(W<=h)if(h=W,v=U-1,v>g)F=Math.max(1,2*g-v);else break}}if(I(H+1,g)>h)break;C=_}return v},n.prototype.match_alphabet_=function(i){for(var c={},g=0;g<i.length;g++)c[i.charAt(g)]=0;for(var g=0;g<i.length;g++)c[i.charAt(g)]|=1<<i.length-g-1;return c},n.prototype.patch_addContext_=function(i,c){if(c.length!=0){if(i.start2===null)throw Error("patch not initialized");for(var g=c.substring(i.start2,i.start2+i.length1),l=0;c.indexOf(g)!=c.lastIndexOf(g)&&g.length<this.Match_MaxBits-this.Patch_Margin-this.Patch_Margin;)l+=this.Patch_Margin,g=c.substring(i.start2-l,i.start2+i.length1+l);l+=this.Patch_Margin;var p=c.substring(i.start2-l,i.start2);p&&i.diffs.unshift(new n.Diff(f,p));var I=c.substring(i.start2+i.length1,i.start2+i.length1+l);I&&i.diffs.push(new n.Diff(f,I)),i.start1-=p.length,i.start2-=p.length,i.length1+=p.length+I.length,i.length2+=p.length+I.length}},n.prototype.patch_make=function(i,c,g){var l,p;if(typeof i=="string"&&typeof c=="string"&&typeof g=="undefined")l=i,p=this.diff_main(l,c,!0),p.length>2&&(this.diff_cleanupSemantic(p),this.diff_cleanupEfficiency(p));else if(i&&typeof i=="object"&&typeof c=="undefined"&&typeof g=="undefined")p=i,l=this.diff_text1(p);else if(typeof i=="string"&&c&&typeof c=="object"&&typeof g=="undefined")l=i,p=c;else if(typeof i=="string"&&typeof c=="string"&&g&&typeof g=="object")l=i,p=g;else throw new Error("Unknown call format to patch_make.");if(p.length===0)return[];for(var I=[],h=new n.patch_obj,v=0,m=0,w=0,B=l,x=l,C=0;C<p.length;C++){var H=p[C][0],F=p[C][1];switch(!v&&H!==f&&(h.start1=m,h.start2=w),H){case o:h.diffs[v++]=p[C],h.length2+=F.length,x=x.substring(0,w)+F+x.substring(w);break;case r:h.length1+=F.length,h.diffs[v++]=p[C],x=x.substring(0,w)+x.substring(w+F.length);break;case f:F.length<=2*this.Patch_Margin&&v&&p.length!=C+1?(h.diffs[v++]=p[C],h.length1+=F.length,h.length2+=F.length):F.length>=2*this.Patch_Margin&&v&&(this.patch_addContext_(h,B),I.push(h),h=new n.patch_obj,v=0,B=x,m=w);break}H!==o&&(m+=F.length),H!==r&&(w+=F.length)}return v&&(this.patch_addContext_(h,B),I.push(h)),I},n.prototype.patch_deepCopy=function(i){for(var c=[],g=0;g<i.length;g++){var l=i[g],p=new n.patch_obj;p.diffs=[];for(var I=0;I<l.diffs.length;I++)p.diffs[I]=new n.Diff(l.diffs[I][0],l.diffs[I][1]);p.start1=l.start1,p.start2=l.start2,p.length1=l.length1,p.length2=l.length2,c[g]=p}return c},n.prototype.patch_apply=function(i,c){if(i.length==0)return[c,[]];i=this.patch_deepCopy(i);var g=this.patch_addPadding(i);c=g+c+g,this.patch_splitMax(i);for(var l=0,p=[],I=0;I<i.length;I++){var h=i[I].start2+l,v=this.diff_text1(i[I].diffs),m,w=-1;if(v.length>this.Match_MaxBits?(m=this.match_main(c,v.substring(0,this.Match_MaxBits),h),m!=-1&&(w=this.match_main(c,v.substring(v.length-this.Match_MaxBits),h+v.length-this.Match_MaxBits),(w==-1||m>=w)&&(m=-1))):m=this.match_main(c,v,h),m==-1)p[I]=!1,l-=i[I].length2-i[I].length1;else{p[I]=!0,l=m-h;var B;if(w==-1?B=c.substring(m,m+v.length):B=c.substring(m,w+this.Match_MaxBits),v==B)c=c.substring(0,m)+this.diff_text2(i[I].diffs)+c.substring(m+v.length);else{var x=this.diff_main(v,B,!1);if(v.length>this.Match_MaxBits&&this.diff_levenshtein(x)/v.length>this.Patch_DeleteThreshold)p[I]=!1;else{this.diff_cleanupSemanticLossless(x);for(var C=0,H,F=0;F<i[I].diffs.length;F++){var N=i[I].diffs[F];N[0]!==f&&(H=this.diff_xIndex(x,C)),N[0]===o?c=c.substring(0,m+H)+N[1]+c.substring(m+H):N[0]===r&&(c=c.substring(0,m+H)+c.substring(m+this.diff_xIndex(x,C+N[1].length))),N[0]!==r&&(C+=N[1].length)}}}}}return c=c.substring(g.length,c.length-g.length),[c,p]},n.prototype.patch_addPadding=function(i){for(var c=this.Patch_Margin,g="",l=1;l<=c;l++)g+=String.fromCharCode(l);for(var l=0;l<i.length;l++)i[l].start1+=c,i[l].start2+=c;var p=i[0],I=p.diffs;if(I.length==0||I[0][0]!=f)I.unshift(new n.Diff(f,g)),p.start1-=c,p.start2-=c,p.length1+=c,p.length2+=c;else if(c>I[0][1].length){var h=c-I[0][1].length;I[0][1]=g.substring(I[0][1].length)+I[0][1],p.start1-=h,p.start2-=h,p.length1+=h,p.length2+=h}if(p=i[i.length-1],I=p.diffs,I.length==0||I[I.length-1][0]!=f)I.push(new n.Diff(f,g)),p.length1+=c,p.length2+=c;else if(c>I[I.length-1][1].length){var h=c-I[I.length-1][1].length;I[I.length-1][1]+=g.substring(0,h),p.length1+=h,p.length2+=h}return g},n.prototype.patch_splitMax=function(i){for(var c=this.Match_MaxBits,g=0;g<i.length;g++)if(!(i[g].length1<=c)){var l=i[g];i.splice(g--,1);for(var p=l.start1,I=l.start2,h="";l.diffs.length!==0;){var v=new n.patch_obj,m=!0;for(v.start1=p-h.length,v.start2=I-h.length,h!==""&&(v.length1=v.length2=h.length,v.diffs.push(new n.Diff(f,h)));l.diffs.length!==0&&v.length1<c-this.Patch_Margin;){var w=l.diffs[0][0],B=l.diffs[0][1];w===o?(v.length2+=B.length,I+=B.length,v.diffs.push(l.diffs.shift()),m=!1):w===r&&v.diffs.length==1&&v.diffs[0][0]==f&&B.length>2*c?(v.length1+=B.length,p+=B.length,m=!1,v.diffs.push(new n.Diff(w,B)),l.diffs.shift()):(B=B.substring(0,c-v.length1-this.Patch_Margin),v.length1+=B.length,p+=B.length,w===f?(v.length2+=B.length,I+=B.length):m=!1,v.diffs.push(new n.Diff(w,B)),B==l.diffs[0][1]?l.diffs.shift():l.diffs[0][1]=l.diffs[0][1].substring(B.length))}h=this.diff_text2(v.diffs),h=h.substring(h.length-this.Patch_Margin);var x=this.diff_text1(l.diffs).substring(0,this.Patch_Margin);x!==""&&(v.length1+=x.length,v.length2+=x.length,v.diffs.length!==0&&v.diffs[v.diffs.length-1][0]===f?v.diffs[v.diffs.length-1][1]+=x:v.diffs.push(new n.Diff(f,x))),m||i.splice(++g,0,v)}}},n.prototype.patch_toText=function(i){for(var c=[],g=0;g<i.length;g++)c[g]=i[g];return c.join("")},n.prototype.patch_fromText=function(i){var c=[];if(!i)return c;for(var g=i.split(`
-`),l=0,p=/^@@ -(\d+),?(\d*) \+(\d+),?(\d*) @@$/;l<g.length;){var I=g[l].match(p);if(!I)throw new Error("Invalid patch string: "+g[l]);var h=new n.patch_obj;for(c.push(h),h.start1=parseInt(I[1],10),I[2]===""?(h.start1--,h.length1=1):I[2]=="0"?h.length1=0:(h.start1--,h.length1=parseInt(I[2],10)),h.start2=parseInt(I[3],10),I[4]===""?(h.start2--,h.length2=1):I[4]=="0"?h.length2=0:(h.start2--,h.length2=parseInt(I[4],10)),l++;l<g.length;){var v=g[l].charAt(0);try{var m=decodeURI(g[l].substring(1))}catch(w){throw new Error("Illegal escape in patch_fromText: "+m)}if(v=="-")h.diffs.push(new n.Diff(r,m));else if(v=="+")h.diffs.push(new n.Diff(o,m));else if(v==" ")h.diffs.push(new n.Diff(f,m));else{if(v=="@")break;if(v!=="")throw new Error('Invalid patch mode "'+v+'" in: '+m)}l++}}return c},n.patch_obj=function(){this.diffs=[],this.start1=null,this.start2=null,this.length1=0,this.length2=0},n.patch_obj.prototype.toString=function(){var i,c;this.length1===0?i=this.start1+",0":this.length1==1?i=this.start1+1:i=this.start1+1+","+this.length1,this.length2===0?c=this.start2+",0":this.length2==1?c=this.start2+1:c=this.start2+1+","+this.length2;for(var g=["@@ -"+i+" +"+c+` @@
-`],l,p=0;p<this.diffs.length;p++){switch(this.diffs[p][0]){case o:l="+";break;case r:l="-";break;case f:l=" ";break}g[p+1]=l+encodeURI(this.diffs[p][1])+`
-`}return g.join("").replace(/%20/g," ")},a.exports=n,a.exports.diff_match_patch=n,a.exports.DIFF_DELETE=r,a.exports.DIFF_INSERT=o,a.exports.DIFF_EQUAL=f})(Kc);var v0=Kc.exports;const Ga=Zr(v0);var li={exports:{}},Ka,cc;function m0(){return cc||(cc=1,Ka={aliceblue:[240,248,255],antiquewhite:[250,235,215],aqua:[0,255,255],aquamarine:[127,255,212],azure:[240,255,255],beige:[245,245,220],bisque:[255,228,196],black:[0,0,0],blanchedalmond:[255,235,205],blue:[0,0,255],blueviolet:[138,43,226],brown:[165,42,42],burlywood:[222,184,135],cadetblue:[95,158,160],chartreuse:[127,255,0],chocolate:[210,105,30],coral:[255,127,80],cornflowerblue:[100,149,237],cornsilk:[255,248,220],crimson:[220,20,60],cyan:[0,255,255],darkblue:[0,0,139],darkcyan:[0,139,139],darkgoldenrod:[184,134,11],darkgray:[169,169,169],darkgreen:[0,100,0],darkgrey:[169,169,169],darkkhaki:[189,183,107],darkmagenta:[139,0,139],darkolivegreen:[85,107,47],darkorange:[255,140,0],darkorchid:[153,50,204],darkred:[139,0,0],darksalmon:[233,150,122],darkseagreen:[143,188,143],darkslateblue:[72,61,139],darkslategray:[47,79,79],darkslategrey:[47,79,79],darkturquoise:[0,206,209],darkviolet:[148,0,211],deeppink:[255,20,147],deepskyblue:[0,191,255],dimgray:[105,105,105],dimgrey:[105,105,105],dodgerblue:[30,144,255],firebrick:[178,34,34],floralwhite:[255,250,240],forestgreen:[34,139,34],fuchsia:[255,0,255],gainsboro:[220,220,220],ghostwhite:[248,248,255],gold:[255,215,0],goldenrod:[218,165,32],gray:[128,128,128],green:[0,128,0],greenyellow:[173,255,47],grey:[128,128,128],honeydew:[240,255,240],hotpink:[255,105,180],indianred:[205,92,92],indigo:[75,0,130],ivory:[255,255,240],khaki:[240,230,140],lavender:[230,230,250],lavenderblush:[255,240,245],lawngreen:[124,252,0],lemonchiffon:[255,250,205],lightblue:[173,216,230],lightcoral:[240,128,128],lightcyan:[224,255,255],lightgoldenrodyellow:[250,250,210],lightgray:[211,211,211],lightgreen:[144,238,144],lightgrey:[211,211,211],lightpink:[255,182,193],lightsalmon:[255,160,122],lightseagreen:[32,178,170],lightskyblue:[135,206,250],lightslategray:[119,136,153],lightslategrey:[119,136,153],lightsteelblue:[176,196,222],lightyellow:[255,255,224],lime:[0,255,0],limegreen:[50,205,50],linen:[250,240,230],magenta:[255,0,255],maroon:[128,0,0],mediumaquamarine:[102,205,170],mediumblue:[0,0,205],mediumorchid:[186,85,211],mediumpurple:[147,112,219],mediumseagreen:[60,179,113],mediumslateblue:[123,104,238],mediumspringgreen:[0,250,154],mediumturquoise:[72,209,204],mediumvioletred:[199,21,133],midnightblue:[25,25,112],mintcream:[245,255,250],mistyrose:[255,228,225],moccasin:[255,228,181],navajowhite:[255,222,173],navy:[0,0,128],oldlace:[253,245,230],olive:[128,128,0],olivedrab:[107,142,35],orange:[255,165,0],orangered:[255,69,0],orchid:[218,112,214],palegoldenrod:[238,232,170],palegreen:[152,251,152],paleturquoise:[175,238,238],palevioletred:[219,112,147],papayawhip:[255,239,213],peachpuff:[255,218,185],peru:[205,133,63],pink:[255,192,203],plum:[221,160,221],powderblue:[176,224,230],purple:[128,0,128],rebeccapurple:[102,51,153],red:[255,0,0],rosybrown:[188,143,143],royalblue:[65,105,225],saddlebrown:[139,69,19],salmon:[250,128,114],sandybrown:[244,164,96],seagreen:[46,139,87],seashell:[255,245,238],sienna:[160,82,45],silver:[192,192,192],skyblue:[135,206,235],slateblue:[106,90,205],slategray:[112,128,144],slategrey:[112,128,144],snow:[255,250,250],springgreen:[0,255,127],steelblue:[70,130,180],tan:[210,180,140],teal:[0,128,128],thistle:[216,191,216],tomato:[255,99,71],turquoise:[64,224,208],violet:[238,130,238],wheat:[245,222,179],white:[255,255,255],whitesmoke:[245,245,245],yellow:[255,255,0],yellowgreen:[154,205,50]}),Ka}var Va,gc;function Vc(){if(gc)return Va;gc=1;const a=m0(),n={};for(const f of Object.keys(a))n[a[f]]=f;const r={rgb:{channels:3,labels:"rgb"},hsl:{channels:3,labels:"hsl"},hsv:{channels:3,labels:"hsv"},hwb:{channels:3,labels:"hwb"},cmyk:{channels:4,labels:"cmyk"},xyz:{channels:3,labels:"xyz"},lab:{channels:3,labels:"lab"},lch:{channels:3,labels:"lch"},hex:{channels:1,labels:["hex"]},keyword:{channels:1,labels:["keyword"]},ansi16:{channels:1,labels:["ansi16"]},ansi256:{channels:1,labels:["ansi256"]},hcg:{channels:3,labels:["h","c","g"]},apple:{channels:3,labels:["r16","g16","b16"]},gray:{channels:1,labels:["gray"]}};Va=r;for(const f of Object.keys(r)){if(!("channels"in r[f]))throw new Error("missing channels property: "+f);if(!("labels"in r[f]))throw new Error("missing channel labels property: "+f);if(r[f].labels.length!==r[f].channels)throw new Error("channel and label counts mismatch: "+f);const{channels:i,labels:c}=r[f];delete r[f].channels,delete r[f].labels,Object.defineProperty(r[f],"channels",{value:i}),Object.defineProperty(r[f],"labels",{value:c})}r.rgb.hsl=function(f){const i=f[0]/255,c=f[1]/255,g=f[2]/255,l=Math.min(i,c,g),p=Math.max(i,c,g),I=p-l;let h,v;p===l?h=0:i===p?h=(c-g)/I:c===p?h=2+(g-i)/I:g===p&&(h=4+(i-c)/I),h=Math.min(h*60,360),h<0&&(h+=360);const m=(l+p)/2;return p===l?v=0:m<=.5?v=I/(p+l):v=I/(2-p-l),[h,v*100,m*100]},r.rgb.hsv=function(f){let i,c,g,l,p;const I=f[0]/255,h=f[1]/255,v=f[2]/255,m=Math.max(I,h,v),w=m-Math.min(I,h,v),B=function(x){return(m-x)/6/w+1/2};return w===0?(l=0,p=0):(p=w/m,i=B(I),c=B(h),g=B(v),I===m?l=g-c:h===m?l=1/3+i-g:v===m&&(l=2/3+c-i),l<0?l+=1:l>1&&(l-=1)),[l*360,p*100,m*100]},r.rgb.hwb=function(f){const i=f[0],c=f[1];let g=f[2];const l=r.rgb.hsl(f)[0],p=1/255*Math.min(i,Math.min(c,g));return g=1-1/255*Math.max(i,Math.max(c,g)),[l,p*100,g*100]},r.rgb.cmyk=function(f){const 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r.rgb.ansi16(r.hsv.rgb(f),f[2])},r.rgb.ansi256=function(f){const i=f[0],c=f[1],g=f[2];return i===c&&c===g?i<8?16:i>248?231:Math.round((i-8)/247*24)+232:16+36*Math.round(i/255*5)+6*Math.round(c/255*5)+Math.round(g/255*5)},r.ansi16.rgb=function(f){let i=f%10;if(i===0||i===7)return f>50&&(i+=3.5),i=i/10.5*255,[i,i,i];const c=(~~(f>50)+1)*.5,g=(i&1)*c*255,l=(i>>1&1)*c*255,p=(i>>2&1)*c*255;return[g,l,p]},r.ansi256.rgb=function(f){if(f>=232){const p=(f-232)*10+8;return[p,p,p]}f-=16;let i;const c=Math.floor(f/36)/5*255,g=Math.floor((i=f%36)/6)/5*255,l=i%6/5*255;return[c,g,l]},r.rgb.hex=function(f){const c=(((Math.round(f[0])&255)<<16)+((Math.round(f[1])&255)<<8)+(Math.round(f[2])&255)).toString(16).toUpperCase();return"000000".substring(c.length)+c},r.hex.rgb=function(f){const i=f.toString(16).match(/[a-f0-9]{6}|[a-f0-9]{3}/i);if(!i)return[0,0,0];let c=i[0];i[0].length===3&&(c=c.split("").map(h=>h+h).join(""));const g=parseInt(c,16),l=g>>16&255,p=g>>8&255,I=g&255;return[l,p,I]},r.rgb.hcg=function(f){const i=f[0]/255,c=f[1]/255,g=f[2]/255,l=Math.max(Math.max(i,c),g),p=Math.min(Math.min(i,c),g),I=l-p;let h,v;return I<1?h=p/(1-I):h=0,I<=0?v=0:l===i?v=(c-g)/I%6:l===c?v=2+(g-i)/I:v=4+(i-c)/I,v/=6,v%=1,[v*360,I*100,h*100]},r.hsl.hcg=function(f){const i=f[1]/100,c=f[2]/100,g=c<.5?2*i*c:2*i*(1-c);let l=0;return g<1&&(l=(c-.5*g)/(1-g)),[f[0],g*100,l*100]},r.hsv.hcg=function(f){const i=f[1]/100,c=f[2]/100,g=i*c;let l=0;return g<1&&(l=(c-g)/(1-g)),[f[0],g*100,l*100]},r.hcg.rgb=function(f){const i=f[0]/360,c=f[1]/100,g=f[2]/100;if(c===0)return[g*255,g*255,g*255];const l=[0,0,0],p=i%1*6,I=p%1,h=1-I;let v=0;switch(Math.floor(p)){case 0:l[0]=1,l[1]=I,l[2]=0;break;case 1:l[0]=h,l[1]=1,l[2]=0;break;case 2:l[0]=0,l[1]=1,l[2]=I;break;case 3:l[0]=0,l[1]=h,l[2]=1;break;case 4:l[0]=I,l[1]=0,l[2]=1;break;default:l[0]=1,l[1]=0,l[2]=h}return v=(1-c)*g,[(c*l[0]+v)*255,(c*l[1]+v)*255,(c*l[2]+v)*255]},r.hcg.hsv=function(f){const i=f[1]/100,c=f[2]/100,g=i+c*(1-i);let l=0;return g>0&&(l=i/g),[f[0],l*100,g*100]},r.hcg.hsl=function(f){const i=f[1]/100,g=f[2]/100*(1-i)+.5*i;let l=0;return g>0&&g<.5?l=i/(2*g):g>=.5&&g<1&&(l=i/(2*(1-g))),[f[0],l*100,g*100]},r.hcg.hwb=function(f){const i=f[1]/100,c=f[2]/100,g=i+c*(1-i);return[f[0],(g-i)*100,(1-g)*100]},r.hwb.hcg=function(f){const i=f[1]/100,g=1-f[2]/100,l=g-i;let p=0;return l<1&&(p=(g-l)/(1-l)),[f[0],l*100,p*100]},r.apple.rgb=function(f){return[f[0]/65535*255,f[1]/65535*255,f[2]/65535*255]},r.rgb.apple=function(f){return[f[0]/255*65535,f[1]/255*65535,f[2]/255*65535]},r.gray.rgb=function(f){return[f[0]/100*255,f[0]/100*255,f[0]/100*255]},r.gray.hsl=function(f){return[0,0,f[0]]},r.gray.hsv=r.gray.hsl,r.gray.hwb=function(f){return[0,100,f[0]]},r.gray.cmyk=function(f){return[0,0,0,f[0]]},r.gray.lab=function(f){return[f[0],0,0]},r.gray.hex=function(f){const 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b0(){if(uc)return Wa;uc=1;const a=Vc(),n=S0(),r={},o=Object.keys(a);function f(c){const g=function(...l){const p=l[0];return p==null?p:(p.length>1&&(l=p),c(l))};return"conversion"in c&&(g.conversion=c.conversion),g}function i(c){const g=function(...l){const p=l[0];if(p==null)return p;p.length>1&&(l=p);const I=c(l);if(typeof I=="object")for(let h=I.length,v=0;v<h;v++)I[v]=Math.round(I[v]);return I};return"conversion"in c&&(g.conversion=c.conversion),g}return o.forEach(c=>{r[c]={},Object.defineProperty(r[c],"channels",{value:a[c].channels}),Object.defineProperty(r[c],"labels",{value:a[c].labels});const g=n(c);Object.keys(g).forEach(p=>{const I=g[p];r[c][p]=i(I),r[c][p].raw=f(I)})}),Wa=r,Wa}li.exports;(function(a){const n=(I,h)=>(...v)=>`\x1B[${I(...v)+h}m`,r=(I,h)=>(...v)=>{const m=I(...v);return`\x1B[${38+h};5;${m}m`},o=(I,h)=>(...v)=>{const m=I(...v);return`\x1B[${38+h};2;${m[0]};${m[1]};${m[2]}m`},f=I=>I,i=(I,h,v)=>[I,h,v],c=(I,h,v)=>{Object.defineProperty(I,h,{get:()=>{const 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N=0;N<f.length;N++)if((N===0||N===f.length-1)&&(f[N]==="G"||f[N]==="C"?(g+=m.initiationWithTerminalGC,l+=w.initiationWithTerminalGC):(f[N]==="A"||f[N]==="T")&&(g+=m.initiationWithTerminalAT,l+=w.initiationWithTerminalAT)),N<f.length-1){const _=f[N]+f[N+1],U=Jr(_).toUpperCase(),L=`${_}/${U}`;if(!m[L]||!w[L])throw new Error(`Could not find value for ${L} of sequence ${a}`);i+=m[L],c+=w[L]}const B=i+g,x=c+l,C=B*v,H=x+p*Math.log(n),F=C/H+I;if(r){const N=Math.log(r),L=(4.29*(yg(a)/100)-3.95)*Math.pow(10,-5)*N+Math.pow(9.4,-6)*Math.pow(N,2);return 1/(1/(F+h)+L)+I}else return F}catch(o){return`Error calculating Tm for sequence ${a}: ${o}`}}function qv(a,n,{monovalentCationConc:r,polymerase:o}={}){try{if(a.length!==2)throw new Error(`${a.length} sequences received when 2 primers were expected`);const f=a.map(g=>Eg(g,n,{monovalentCationConc:r}));f.sort((g,l)=>g-l);const i=f[0];let c;return o==="Q5"?(c=i+1,c>72&&(c=72)):c=i-3,c}catch(f){return`Error calculating annealing temperature: ${f}`}}function Cg(a,n,r,o={}){const f=[],i=[];if(!r.length)return[];let c=r.sort((g,l)=>g.topSnipPosition-l.topSnipPosition);return n||(c=[{topSnipPosition:0,bottomSnipPosition:0,overhangSize:0,type:"START_OR_END_OF_SEQ",name:"START_OF_SEQ"},...c,{topSnipPosition:a,bottomSnipPosition:a,overhangSize:0,type:"START_OR_END_OF_SEQ",name:"END_OF_SEQ"}]),c.forEach((g,l)=>{!n&&!c[l+1]||(o.computePartialDigests&&c.forEach((p,I)=>{I===l+1||I===0||i.push([g,c[I]])}),i.push([g,c[l+1]?c[l+1]:c[0]]))}),i.forEach(([g,l])=>{const p=ae(g.topSnipPosition,a),I=ae(l.topSnipPosition-1,a),h={start:p,end:I},v=xe(h,a),m=p+"-"+I+"-"+v+"-";f.push(Se(se({cut1:Se(se({},g),{isOverhangIncludedInFragmentSize:g.type!=="START_OR_END_OF_SEQ"&&g.overhangSize>0&&g.topSnipBeforeBottom}),cut2:Se(se({},l),{isOverhangIncludedInFragmentSize:l.type!=="START_OR_END_OF_SEQ"&&l.overhangSize>0&&!l.topSnipBeforeBottom})},h),{size:v,id:m}))}),f.filter(g=>!!g.size),f}function Wv(a,n,r,o){const f=Array.isArray(r)?r:[r],i=V.flatMap(f,c=>ls(a,n,c));return Cg(a.length,n,i,o)}function $v(a){return typeof a=="object"&&a!==null?_c(Se(se({},a),{locations:a.locations?a.locations.map(_c):void 0})):jv(a)}function jv(a){return a*3}function _c(a){return Se(se({},a),{start:a.start>-1?a.start*3:a.start,end:a.end>-1?a.end*3+2:a.end})}const Xv=V.invert(vi);function zv(a,n=2,r=!1){let o=0;for(let f=0;f<a.length;f++)o+=k[a[f]].mass;return r&&(o/=3),Math.round(o*we(10,n))/we(10,n)}function Jv({seqData:a,caretPosition:n,insertLength:r}){zr.forEach(o=>{const f=a[o];a[o]=fs(f,n,r)})}const 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array=arrays[index2],othIndex=-1;while(++othIndex<length){if(othIndex!=index2){result2[index2]=baseDifference(result2[index2]||array,arrays[othIndex],iteratee2,comparator)}}}return baseUniq(baseFlatten(result2,1),iteratee2,comparator)}__name(baseXor,"baseXor");function baseZipObject(props,values2,assignFunc){var index2=-1,length=props.length,valsLength=values2.length,result2={};while(++index2<length){var value=index2<valsLength?values2[index2]:undefined$1;assignFunc(result2,props[index2],value)}return result2}__name(baseZipObject,"baseZipObject");function castArrayLikeObject(value){return isArrayLikeObject(value)?value:[]}__name(castArrayLikeObject,"castArrayLikeObject");function castFunction(value){return typeof value=="function"?value:identity}__name(castFunction,"castFunction");function castPath(value,object){if(isArray2(value)){return value}return isKey(value,object)?[value]:stringToPath(toString(value))}__name(castPath,"castPath");var castRest=baseRest;function 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othIsDefined=other!==undefined$1,othIsNull=other===null,othIsReflexive=other===other,othIsSymbol=isSymbol(other);if(!othIsNull&&!othIsSymbol&&!valIsSymbol&&value>other||valIsSymbol&&othIsDefined&&othIsReflexive&&!othIsNull&&!othIsSymbol||valIsNull&&othIsDefined&&othIsReflexive||!valIsDefined&&othIsReflexive||!valIsReflexive){return 1}if(!valIsNull&&!valIsSymbol&&!othIsSymbol&&value<other||othIsSymbol&&valIsDefined&&valIsReflexive&&!valIsNull&&!valIsSymbol||othIsNull&&valIsDefined&&valIsReflexive||!othIsDefined&&valIsReflexive||!othIsReflexive){return-1}}return 0}__name(compareAscending,"compareAscending");function compareMultiple(object,other,orders){var index2=-1,objCriteria=object.criteria,othCriteria=other.criteria,length=objCriteria.length,ordersLength=orders.length;while(++index2<length){var result2=compareAscending(objCriteria[index2],othCriteria[index2]);if(result2){if(index2>=ordersLength){return result2}var order=orders[index2];return result2*(order=="desc"?-1:1)}}return object.index-other.index}__name(compareMultiple,"compareMultiple");function composeArgs(args,partials,holders,isCurried){var argsIndex=-1,argsLength=args.length,holdersLength=holders.length,leftIndex=-1,leftLength=partials.length,rangeLength=nativeMax(argsLength-holdersLength,0),result2=Array2(leftLength+rangeLength),isUncurried=!isCurried;while(++leftIndex<leftLength){result2[leftIndex]=partials[leftIndex]}while(++argsIndex<holdersLength){if(isUncurried||argsIndex<argsLength){result2[holders[argsIndex]]=args[argsIndex]}}while(rangeLength--){result2[leftIndex++]=args[argsIndex++]}return result2}__name(composeArgs,"composeArgs");function composeArgsRight(args,partials,holders,isCurried){var argsIndex=-1,argsLength=args.length,holdersIndex=-1,holdersLength=holders.length,rightIndex=-1,rightLength=partials.length,rangeLength=nativeMax(argsLength-holdersLength,0),result2=Array2(rangeLength+rightLength),isUncurried=!isCurried;while(++argsIndex<rangeLength){result2[argsIndex]=args[argsIndex]}var offset=argsIndex;while(++rightIndex<rightLength){result2[offset+rightIndex]=partials[rightIndex]}while(++holdersIndex<holdersLength){if(isUncurried||argsIndex<argsLength){result2[offset+holders[holdersIndex]]=args[argsIndex++]}}return result2}__name(composeArgsRight,"composeArgsRight");function copyArray(source2,array){var index2=-1,length=source2.length;array||(array=Array2(length));while(++index2<length){array[index2]=source2[index2]}return array}__name(copyArray,"copyArray");function copyObject(source2,props,object,customizer){var isNew=!object;object||(object={});var index2=-1,length=props.length;while(++index2<length){var key=props[index2];var newValue=customizer?customizer(object[key],source2[key],key,object,source2):undefined$1;if(newValue===undefined$1){newValue=source2[key]}if(isNew){baseAssignValue(object,key,newValue)}else{assignValue(object,key,newValue)}}return object}__name(copyObject,"copyObject");function copySymbols(source2,object){return copyObject(source2,getSymbols(source2),object)}__name(copySymbols,"copySymbols");function copySymbolsIn(source2,object){return copyObject(source2,getSymbolsIn(source2),object)}__name(copySymbolsIn,"copySymbolsIn");function createAggregator(setter,initializer){return function(collection,iteratee2){var func=isArray2(collection)?arrayAggregator:baseAggregator,accumulator=initializer?initializer():{};return func(collection,setter,getIteratee(iteratee2,2),accumulator)}}__name(createAggregator,"createAggregator");function createAssigner(assigner){return baseRest(function(object,sources){var index2=-1,length=sources.length,customizer=length>1?sources[length-1]:undefined$1,guard=length>2?sources[2]:undefined$1;customizer=assigner.length>3&&typeof customizer=="function"?(length--,customizer):undefined$1;if(guard&&isIterateeCall(sources[0],sources[1],guard)){customizer=length<3?undefined$1:customizer;length=1}object=Object2(object);while(++index2<length){var source2=sources[index2];if(source2){assigner(object,source2,index2,customizer)}}return object})}__name(createAssigner,"createAssigner");function createBaseEach(eachFunc,fromRight){return function(collection,iteratee2){if(collection==null){return collection}if(!isArrayLike(collection)){return eachFunc(collection,iteratee2)}var length=collection.length,index2=fromRight?length:-1,iterable=Object2(collection);while(fromRight?index2--:++index2<length){if(iteratee2(iterable[index2],index2,iterable)===false){break}}return collection}}__name(createBaseEach,"createBaseEach");function createBaseFor(fromRight){return function(object,iteratee2,keysFunc){var index2=-1,iterable=Object2(object),props=keysFunc(object),length=props.length;while(length--){var key=props[fromRight?length:++index2];if(iteratee2(iterable[key],key,iterable)===false){break}}return object}}__name(createBaseFor,"createBaseFor");function createBind(func,bitmask,thisArg){var isBind=bitmask&WRAP_BIND_FLAG,Ctor=createCtor(func);function wrapper(){var fn=this&&this!==root&&this instanceof wrapper?Ctor:func;return fn.apply(isBind?thisArg:this,arguments)}__name(wrapper,"wrapper");return wrapper}__name(createBind,"createBind");function createCaseFirst(methodName){return function(string){string=toString(string);var strSymbols=hasUnicode(string)?stringToArray(string):undefined$1;var chr=strSymbols?strSymbols[0]:string.charAt(0);var trailing=strSymbols?castSlice(strSymbols,1).join(""):string.slice(1);return chr[methodName]()+trailing}}__name(createCaseFirst,"createCaseFirst");function createCompounder(callback){return function(string){return arrayReduce(words(deburr(string).replace(reApos,"")),callback,"")}}__name(createCompounder,"createCompounder");function createCtor(Ctor){return function(){var args=arguments;switch(args.length){case 0:return new Ctor;case 1:return new Ctor(args[0]);case 2:return new Ctor(args[0],args[1]);case 3:return new Ctor(args[0],args[1],args[2]);case 4:return new Ctor(args[0],args[1],args[2],args[3]);case 5:return new Ctor(args[0],args[1],args[2],args[3],args[4]);case 6:return new Ctor(args[0],args[1],args[2],args[3],args[4],args[5]);case 7:return new Ctor(args[0],args[1],args[2],args[3],args[4],args[5],args[6])}var thisBinding=baseCreate(Ctor.prototype),result2=Ctor.apply(thisBinding,args);return isObject(result2)?result2:thisBinding}}__name(createCtor,"createCtor");function createCurry(func,bitmask,arity){var Ctor=createCtor(func);function wrapper(){var length=arguments.length,args=Array2(length),index2=length,placeholder=getHolder(wrapper);while(index2--){args[index2]=arguments[index2]}var holders=length<3&&args[0]!==placeholder&&args[length-1]!==placeholder?[]:replaceHolders(args,placeholder);length-=holders.length;if(length<arity){return createRecurry(func,bitmask,createHybrid,wrapper.placeholder,undefined$1,args,holders,undefined$1,undefined$1,arity-length)}var fn=this&&this!==root&&this instanceof wrapper?Ctor:func;return apply(fn,this,args)}__name(wrapper,"wrapper");return wrapper}__name(createCurry,"createCurry");function createFind(findIndexFunc){return function(collection,predicate,fromIndex){var iterable=Object2(collection);if(!isArrayLike(collection)){var iteratee2=getIteratee(predicate,3);collection=keys(collection);predicate=__name(function(key){return iteratee2(iterable[key],key,iterable)},"predicate")}var index2=findIndexFunc(collection,predicate,fromIndex);return index2>-1?iterable[iteratee2?collection[index2]:index2]:undefined$1}}__name(createFind,"createFind");function createFlow(fromRight){return flatRest(function(funcs){var length=funcs.length,index2=length,prereq=LodashWrapper.prototype.thru;if(fromRight){funcs.reverse()}while(index2--){var func=funcs[index2];if(typeof func!="function"){throw new TypeError2(FUNC_ERROR_TEXT)}if(prereq&&!wrapper&&getFuncName(func)=="wrapper"){var wrapper=new LodashWrapper([],true)}}index2=wrapper?index2:length;while(++index2<length){func=funcs[index2];var funcName=getFuncName(func),data=funcName=="wrapper"?getData(func):undefined$1;if(data&&isLaziable(data[0])&&data[1]==(WRAP_ARY_FLAG|WRAP_CURRY_FLAG|WRAP_PARTIAL_FLAG|WRAP_REARG_FLAG)&&!data[4].length&&data[9]==1){wrapper=wrapper[getFuncName(data[0])].apply(wrapper,data[3])}else{wrapper=func.length==1&&isLaziable(func)?wrapper[funcName]():wrapper.thru(func)}}return function(){var args=arguments,value=args[0];if(wrapper&&args.length==1&&isArray2(value)){return wrapper.plant(value).value()}var index3=0,result2=length?funcs[index3].apply(this,args):value;while(++index3<length){result2=funcs[index3].call(this,result2)}return result2}})}__name(createFlow,"createFlow");function createHybrid(func,bitmask,thisArg,partials,holders,partialsRight,holdersRight,argPos,ary2,arity){var isAry=bitmask&WRAP_ARY_FLAG,isBind=bitmask&WRAP_BIND_FLAG,isBindKey=bitmask&WRAP_BIND_KEY_FLAG,isCurried=bitmask&(WRAP_CURRY_FLAG|WRAP_CURRY_RIGHT_FLAG),isFlip=bitmask&WRAP_FLIP_FLAG,Ctor=isBindKey?undefined$1:createCtor(func);function wrapper(){var length=arguments.length,args=Array2(length),index2=length;while(index2--){args[index2]=arguments[index2]}if(isCurried){var placeholder=getHolder(wrapper),holdersCount=countHolders(args,placeholder)}if(partials){args=composeArgs(args,partials,holders,isCurried)}if(partialsRight){args=composeArgsRight(args,partialsRight,holdersRight,isCurried)}length-=holdersCount;if(isCurried&&length<arity){var newHolders=replaceHolders(args,placeholder);return createRecurry(func,bitmask,createHybrid,wrapper.placeholder,thisArg,args,newHolders,argPos,ary2,arity-length)}var thisBinding=isBind?thisArg:this,fn=isBindKey?thisBinding[func]:func;length=args.length;if(argPos){args=reorder(args,argPos)}else if(isFlip&&length>1){args.reverse()}if(isAry&&ary2<length){args.length=ary2}if(this&&this!==root&&this instanceof wrapper){fn=Ctor||createCtor(fn)}return fn.apply(thisBinding,args)}__name(wrapper,"wrapper");return wrapper}__name(createHybrid,"createHybrid");function createInverter(setter,toIteratee){return function(object,iteratee2){return baseInverter(object,setter,toIteratee(iteratee2),{})}}__name(createInverter,"createInverter");function createMathOperation(operator,defaultValue){return function(value,other){var result2;if(value===undefined$1&&other===undefined$1){return defaultValue}if(value!==undefined$1){result2=value}if(other!==undefined$1){if(result2===undefined$1){return other}if(typeof value=="string"||typeof other=="string"){value=baseToString(value);other=baseToString(other)}else{value=baseToNumber(value);other=baseToNumber(other)}result2=operator(value,other)}return result2}}__name(createMathOperation,"createMathOperation");function createOver(arrayFunc){return flatRest(function(iteratees){iteratees=arrayMap(iteratees,baseUnary(getIteratee()));return baseRest(function(args){var thisArg=this;return arrayFunc(iteratees,function(iteratee2){return apply(iteratee2,thisArg,args)})})})}__name(createOver,"createOver");function createPadding(length,chars){chars=chars===undefined$1?" 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in Object2(object))}}__name(matchesStrictComparable,"matchesStrictComparable");function memoizeCapped(func){var result2=memoize(func,function(key){if(cache.size===MAX_MEMOIZE_SIZE){cache.clear()}return key});var cache=result2.cache;return result2}__name(memoizeCapped,"memoizeCapped");function mergeData(data,source2){var bitmask=data[1],srcBitmask=source2[1],newBitmask=bitmask|srcBitmask,isCommon=newBitmask<(WRAP_BIND_FLAG|WRAP_BIND_KEY_FLAG|WRAP_ARY_FLAG);var isCombo=srcBitmask==WRAP_ARY_FLAG&&bitmask==WRAP_CURRY_FLAG||srcBitmask==WRAP_ARY_FLAG&&bitmask==WRAP_REARG_FLAG&&data[7].length<=source2[8]||srcBitmask==(WRAP_ARY_FLAG|WRAP_REARG_FLAG)&&source2[7].length<=source2[8]&&bitmask==WRAP_CURRY_FLAG;if(!(isCommon||isCombo)){return data}if(srcBitmask&WRAP_BIND_FLAG){data[2]=source2[2];newBitmask|=bitmask&WRAP_BIND_FLAG?0:WRAP_CURRY_BOUND_FLAG}var value=source2[3];if(value){var partials=data[3];data[3]=partials?composeArgs(partials,value,source2[4]):value;data[4]=partials?replaceHolders(data[3],PLACEHOLDER):source2[4]}value=source2[5];if(value){partials=data[5];data[5]=partials?composeArgsRight(partials,value,source2[6]):value;data[6]=partials?replaceHolders(data[5],PLACEHOLDER):source2[6]}value=source2[7];if(value){data[7]=value}if(srcBitmask&WRAP_ARY_FLAG){data[8]=data[8]==null?source2[8]:nativeMin(data[8],source2[8])}if(data[9]==null){data[9]=source2[9]}data[0]=source2[0];data[1]=newBitmask;return data}__name(mergeData,"mergeData");function nativeKeysIn(object){var result2=[];if(object!=null){for(var key in Object2(object)){result2.push(key)}}return result2}__name(nativeKeysIn,"nativeKeysIn");function objectToString(value){return nativeObjectToString.call(value)}__name(objectToString,"objectToString");function overRest(func,start,transform2){start=nativeMax(start===undefined$1?func.length-1:start,0);return function(){var args=arguments,index2=-1,length=nativeMax(args.length-start,0),array=Array2(length);while(++index2<length){array[index2]=args[start+index2]}index2=-1;var otherArgs=Array2(start+1);while(++index2<start){otherArgs[index2]=args[index2]}otherArgs[start]=transform2(array);return apply(func,this,otherArgs)}}__name(overRest,"overRest");function parent(object,path){return path.length<2?object:baseGet(object,baseSlice(path,0,-1))}__name(parent,"parent");function reorder(array,indexes){var arrLength=array.length,length=nativeMin(indexes.length,arrLength),oldArray=copyArray(array);while(length--){var index2=indexes[length];array[length]=isIndex(index2,arrLength)?oldArray[index2]:undefined$1}return array}__name(reorder,"reorder");function safeGet(object,key){if(key==="constructor"&&typeof object[key]==="function"){return}if(key=="__proto__"){return}return object[key]}__name(safeGet,"safeGet");var setData=shortOut(baseSetData);var setTimeout=ctxSetTimeout||function(func,wait){return 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result2=[];if(string.charCodeAt(0)===46){result2.push("")}string.replace(rePropName,function(match,number,quote,subString){result2.push(quote?subString.replace(reEscapeChar,"$1"):number||match)});return result2});function toKey(value){if(typeof value=="string"||isSymbol(value)){return value}var result2=value+"";return result2=="0"&&1/value==-INFINITY?"-0":result2}__name(toKey,"toKey");function toSource(func){if(func!=null){try{return funcToString.call(func)}catch(e){}try{return func+""}catch(e){}}return""}__name(toSource,"toSource");function updateWrapDetails(details,bitmask){arrayEach(wrapFlags,function(pair){var value="_."+pair[0];if(bitmask&pair[1]&&!arrayIncludes(details,value)){details.push(value)}});return details.sort()}__name(updateWrapDetails,"updateWrapDetails");function wrapperClone(wrapper){if(wrapper instanceof LazyWrapper){return wrapper.clone()}var result2=new 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length=array==null?0:array.length;if(!length){return-1}var index2=fromIndex==null?0:toInteger(fromIndex);if(index2<0){index2=nativeMax(length+index2,0)}return baseFindIndex(array,getIteratee(predicate,3),index2)}__name(findIndex,"findIndex");function findLastIndex(array,predicate,fromIndex){var length=array==null?0:array.length;if(!length){return-1}var index2=length-1;if(fromIndex!==undefined$1){index2=toInteger(fromIndex);index2=fromIndex<0?nativeMax(length+index2,0):nativeMin(index2,length-1)}return baseFindIndex(array,getIteratee(predicate,3),index2,true)}__name(findLastIndex,"findLastIndex");function flatten(array){var length=array==null?0:array.length;return length?baseFlatten(array,1):[]}__name(flatten,"flatten");function flattenDeep(array){var length=array==null?0:array.length;return length?baseFlatten(array,INFINITY):[]}__name(flattenDeep,"flattenDeep");function flattenDepth(array,depth){var 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array&&array.length?baseWhile(array,getIteratee(predicate,3)):[]}__name(takeWhile,"takeWhile");var union=baseRest(function(arrays){return baseUniq(baseFlatten(arrays,1,isArrayLikeObject,true))});var unionBy=baseRest(function(arrays){var iteratee2=last(arrays);if(isArrayLikeObject(iteratee2)){iteratee2=undefined$1}return baseUniq(baseFlatten(arrays,1,isArrayLikeObject,true),getIteratee(iteratee2,2))});var unionWith=baseRest(function(arrays){var comparator=last(arrays);comparator=typeof comparator=="function"?comparator:undefined$1;return baseUniq(baseFlatten(arrays,1,isArrayLikeObject,true),undefined$1,comparator)});function uniq(array){return array&&array.length?baseUniq(array):[]}__name(uniq,"uniq");function uniqBy(array,iteratee2){return array&&array.length?baseUniq(array,getIteratee(iteratee2,2)):[]}__name(uniqBy,"uniqBy");function uniqWith(array,comparator){comparator=typeof comparator=="function"?comparator:undefined$1;return 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this.thru(reverse2)}__name(wrapperReverse,"wrapperReverse");function wrapperValue(){return baseWrapperValue(this.__wrapped__,this.__actions__)}__name(wrapperValue,"wrapperValue");var countBy=createAggregator(function(result2,value,key){if(hasOwnProperty.call(result2,key)){++result2[key]}else{baseAssignValue(result2,key,1)}});function every(collection,predicate,guard){var func=isArray2(collection)?arrayEvery:baseEvery;if(guard&&isIterateeCall(collection,predicate,guard)){predicate=undefined$1}return func(collection,getIteratee(predicate,3))}__name(every,"every");function filter(collection,predicate){var func=isArray2(collection)?arrayFilter:baseFilter;return func(collection,getIteratee(predicate,3))}__name(filter,"filter");var find=createFind(findIndex);var findLast=createFind(findLastIndex);function flatMap(collection,iteratee2){return baseFlatten(map(collection,iteratee2),1)}__name(flatMap,"flatMap");function flatMapDeep(collection,iteratee2){return 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func=isArray2(collection)?arrayFilter:baseFilter;return func(collection,negate(getIteratee(predicate,3)))}__name(reject,"reject");function sample(collection){var func=isArray2(collection)?arraySample:baseSample;return func(collection)}__name(sample,"sample");function sampleSize(collection,n,guard){if(guard?isIterateeCall(collection,n,guard):n===undefined$1){n=1}else{n=toInteger(n)}var func=isArray2(collection)?arraySampleSize:baseSampleSize;return func(collection,n)}__name(sampleSize,"sampleSize");function shuffle(collection){var func=isArray2(collection)?arrayShuffle:baseShuffle;return func(collection)}__name(shuffle,"shuffle");function size(collection){if(collection==null){return 0}if(isArrayLike(collection)){return isString(collection)?stringSize(collection):collection.length}var tag=getTag(collection);if(tag==mapTag||tag==setTag){return collection.size}return baseKeys(collection).length}__name(size,"size");function some(collection,predicate,guard){var 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curryRight(func,arity,guard){arity=guard?undefined$1:arity;var result2=createWrap(func,WRAP_CURRY_RIGHT_FLAG,undefined$1,undefined$1,undefined$1,undefined$1,undefined$1,arity);result2.placeholder=curryRight.placeholder;return result2}__name(curryRight,"curryRight");function debounce(func,wait,options){var lastArgs,lastThis,maxWait,result2,timerId,lastCallTime,lastInvokeTime=0,leading=false,maxing=false,trailing=true;if(typeof func!="function"){throw new TypeError2(FUNC_ERROR_TEXT)}wait=toNumber(wait)||0;if(isObject(options)){leading=!!options.leading;maxing="maxWait"in options;maxWait=maxing?nativeMax(toNumber(options.maxWait)||0,wait):maxWait;trailing="trailing"in options?!!options.trailing:trailing}function invokeFunc(time){var args=lastArgs,thisArg=lastThis;lastArgs=lastThis=undefined$1;lastInvokeTime=time;result2=func.apply(thisArg,args);return result2}__name(invokeFunc,"invokeFunc");function leadingEdge(time){lastInvokeTime=time;timerId=setTimeout(timerExpired,wait);return leading?invokeFunc(time):result2}__name(leadingEdge,"leadingEdge");function remainingWait(time){var timeSinceLastCall=time-lastCallTime,timeSinceLastInvoke=time-lastInvokeTime,timeWaiting=wait-timeSinceLastCall;return maxing?nativeMin(timeWaiting,maxWait-timeSinceLastInvoke):timeWaiting}__name(remainingWait,"remainingWait");function shouldInvoke(time){var timeSinceLastCall=time-lastCallTime,timeSinceLastInvoke=time-lastInvokeTime;return lastCallTime===undefined$1||timeSinceLastCall>=wait||timeSinceLastCall<0||maxing&&timeSinceLastInvoke>=maxWait}__name(shouldInvoke,"shouldInvoke");function timerExpired(){var time=now();if(shouldInvoke(time)){return trailingEdge(time)}timerId=setTimeout(timerExpired,remainingWait(time))}__name(timerExpired,"timerExpired");function trailingEdge(time){timerId=undefined$1;if(trailing&&lastArgs){return invokeFunc(time)}lastArgs=lastThis=undefined$1;return result2}__name(trailingEdge,"trailingEdge");function 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overArgs=castRest(function(func,transforms){transforms=transforms.length==1&&isArray2(transforms[0])?arrayMap(transforms[0],baseUnary(getIteratee())):arrayMap(baseFlatten(transforms,1),baseUnary(getIteratee()));var funcsLength=transforms.length;return baseRest(function(args){var index2=-1,length=nativeMin(args.length,funcsLength);while(++index2<length){args[index2]=transforms[index2].call(this,args[index2])}return apply(func,this,args)})});var partial=baseRest(function(func,partials){var holders=replaceHolders(partials,getHolder(partial));return createWrap(func,WRAP_PARTIAL_FLAG,undefined$1,partials,holders)});var partialRight=baseRest(function(func,partials){var holders=replaceHolders(partials,getHolder(partialRight));return createWrap(func,WRAP_PARTIAL_RIGHT_FLAG,undefined$1,partials,holders)});var rearg=flatRest(function(func,indexes){return createWrap(func,WRAP_REARG_FLAG,undefined$1,undefined$1,undefined$1,indexes)});function rest(func,start){if(typeof func!="function"){throw new 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checkIteratee=/^(?:filter|find|map|reject)|While$/.test(methodName),isTaker=/^(?:head|last)$/.test(methodName),lodashFunc=lodash2[isTaker?"take"+(methodName=="last"?"Right":""):methodName],retUnwrapped=isTaker||/^find/.test(methodName);if(!lodashFunc){return}lodash2.prototype[methodName]=function(){var value=this.__wrapped__,args=isTaker?[1]:arguments,isLazy=value instanceof LazyWrapper,iteratee2=args[0],useLazy=isLazy||isArray2(value);var interceptor=__name(function(value2){var result3=lodashFunc.apply(lodash2,arrayPush([value2],args));return isTaker&&chainAll?result3[0]:result3},"interceptor");if(useLazy&&checkIteratee&&typeof iteratee2=="function"&&iteratee2.length!=1){isLazy=useLazy=false}var chainAll=this.__chain__,isHybrid=!!this.__actions__.length,isUnwrapped=retUnwrapped&&!chainAll,onlyLazy=isLazy&&!isHybrid;if(!retUnwrapped&&useLazy){value=onlyLazy?value:new LazyWrapper(this);var result2=func.apply(value,args);result2.__actions__.push({"func":thru,"args":[interceptor],"thisArg":undefined$1});return new LodashWrapper(result2,chainAll)}if(isUnwrapped&&onlyLazy){return func.apply(this,args)}result2=this.thru(interceptor);return isUnwrapped?isTaker?result2.value()[0]:result2.value():result2}});arrayEach(["pop","push","shift","sort","splice","unshift"],function(methodName){var func=arrayProto[methodName],chainName=/^(?:push|sort|unshift)$/.test(methodName)?"tap":"thru",retUnwrapped=/^(?:pop|shift)$/.test(methodName);lodash2.prototype[methodName]=function(){var args=arguments;if(retUnwrapped&&!this.__chain__){var value=this.value();return func.apply(isArray2(value)?value:[],args)}return this[chainName](function(value2){return func.apply(isArray2(value2)?value2:[],args)})}});baseForOwn(LazyWrapper.prototype,function(func,methodName){var lodashFunc=lodash2[methodName];if(lodashFunc){var key=lodashFunc.name+"";if(!hasOwnProperty.call(realNames,key)){realNames[key]=[]}realNames[key].push({"name":methodName,"func":lodashFunc})}});realNames[createHybrid(undefined$1,WRAP_BIND_KEY_FLAG).name]=[{"name":"wrapper","func":undefined$1}];LazyWrapper.prototype.clone=lazyClone;LazyWrapper.prototype.reverse=lazyReverse;LazyWrapper.prototype.value=lazyValue;lodash2.prototype.at=wrapperAt;lodash2.prototype.chain=wrapperChain;lodash2.prototype.commit=wrapperCommit;lodash2.prototype.next=wrapperNext;lodash2.prototype.plant=wrapperPlant;lodash2.prototype.reverse=wrapperReverse;lodash2.prototype.toJSON=lodash2.prototype.valueOf=lodash2.prototype.value=wrapperValue;lodash2.prototype.first=lodash2.prototype.head;if(symIterator){lodash2.prototype[symIterator]=wrapperToIterator}return lodash2},"runInContext");var _=runInContext();if(freeModule){(freeModule.exports=_)._=_;freeExports._=_}else{root._=_}}).call(commonjsGlobal)})(lodash,lodash.exports);var lodashExports=lodash.exports;const protein_letters="ACDEFGHIKLMNPQRSTVWY";const extended_protein_letters="ACDEFGHIKLMNPQRSTVWYBXZJUO.*-";const protein_letters_1to3={A:"Ala",C:"Cys",D:"Asp",E:"Glu",F:"Phe",G:"Gly",H:"His",I:"Ile",K:"Lys",L:"Leu",M:"Met",N:"Asn",P:"Pro",Q:"Gln",R:"Arg",S:"Ser",T:"Thr",V:"Val",W:"Trp",Y:"Tyr",O:"Pyl",U:"Sec"};const ambiguous_dna_letters="GATCRYWSMKHBVDN";const unambiguous_dna_letters="GATC";const ambiguous_rna_letters="GAUCRYWSMKHBVDN";const unambiguous_rna_letters="GAUC";const extended_dna_letters="GATCBDSW";const ambiguous_dna_values={".":".",A:"A",C:"C",G:"G",T:"T",M:"AC",R:"AG",W:"AT",S:"CG",Y:"CT",K:"GT",V:"ACG",H:"ACT",D:"AGT",B:"CGT",X:"GATC",N:"GATC"};const ambiguous_rna_values={".":".",A:"A",C:"C",G:"G",U:"U",M:"AC",R:"AG",W:"AU",S:"CG",Y:"CU",K:"GU",V:"ACG",H:"ACU",D:"AGU",B:"CGU",X:"GAUC",N:"GAUC"};const ambiguous_dna_complement={".":".",A:"T",C:"G",G:"C",T:"A",M:"K",R:"Y",W:"W",S:"S",Y:"R",K:"M",V:"B",H:"D",D:"H",B:"V",X:"X",N:"N"};const ambiguous_rna_complement={".":".",A:"U",C:"G",G:"C",U:"A",M:"K",R:"Y",W:"W",S:"S",Y:"R",K:"M",V:"B",H:"D",D:"H",B:"V",X:"X",N:"N"};const unambiguous_dna_weights={A:331.2218,C:307.1971,G:347.2212,T:322.2085};const monoisotopic_unambiguous_dna_weights={A:331.06817,C:307.056936,G:347.063084,T:322.056602};const unambiguous_rna_weights={A:347.2212,C:323.1965,G:363.2206,U:324.1813};const monoisotopic_unambiguous_rna_weights={A:347.063084,C:323.051851,G:363.057999,U:324.035867};const protein_weights={A:89.0932,C:121.1582,D:133.1027,E:147.1293,F:165.1891,G:75.0666,H:155.1546,I:131.1729,K:146.1876,L:131.1729,M:149.2113,N:132.1179,O:255.3134,P:115.1305,Q:146.1445,R:174.201,S:105.0926,T:119.1192,U:168.0532,V:117.1463,W:204.2252,Y:181.1885};const monoisotopic_protein_weights={A:89.047678,C:121.019749,D:133.037508,E:147.053158,F:165.078979,G:75.032028,H:155.069477,I:131.094629,K:146.105528,L:131.094629,M:149.051049,N:132.053492,O:255.158292,P:115.063329,Q:146.069142,R:174.111676,S:105.042593,T:119.058243,U:168.964203,V:117.078979,W:204.089878,Y:181.073893};const extended_protein_values={A:"A",B:"ND",C:"C",D:"D",E:"E",F:"F",G:"G",H:"H",I:"I",J:"IL",K:"K",L:"L",M:"M",N:"N",O:"O",P:"P",Q:"Q",R:"R",S:"S",T:"T",U:"U",V:"V",W:"W",X:"ACDEFGHIKLMNPQRSTVWY",Y:"Y",Z:"QE","*":"\\*\\.",".":"\\.\\.","-":"\\-"};const atom_weights={H:1.00794,D:2.0141,He:4.002602,Li:6.941,Be:9.012182,B:10.811,C:12.0107,N:14.0067,O:15.9994,F:18.9984032,Ne:20.1797,Na:22.98977,Mg:24.305,Al:26.981538,Si:28.0855,P:30.973761,S:32.065,Cl:35.453,Ar:39.948,K:39.0983,Ca:40.078,Sc:44.95591,Ti:47.867,V:50.9415,Cr:51.9961,Mn:54.938049,Fe:55.845,Co:58.9332,Ni:58.6934,Cu:63.546,Zn:65.39,Ga:69.723,Ge:72.64,As:74.9216,Se:78.96,Br:79.904,Kr:83.8,Rb:85.4678,Sr:87.62,Y:88.90585,Zr:91.224,Nb:92.90638,Mo:95.94,Tc:98,Ru:101.07,Rh:102.9055,Pd:106.42,Ag:107.8682,Cd:112.411,In:114.818,Sn:118.71,Sb:121.76,Te:127.6,I:126.90447,Xe:131.293,Cs:132.90545,Ba:137.327,La:138.9055,Ce:140.116,Pr:140.90765,Nd:144.24,Pm:145,Sm:150.36,Eu:151.964,Gd:157.25,Tb:158.92534,Dy:162.5,Ho:164.93032,Er:167.259,Tm:168.93421,Yb:173.04,Lu:174.967,Hf:178.49,Ta:180.9479,W:183.84,Re:186.207,Os:190.23,Ir:192.217,Pt:195.078,Au:196.96655,Hg:200.59,Tl:204.3833,Pb:207.2,Bi:208.98038,Po:208.98,At:209.99,Rn:222.02,Fr:223.02,Ra:226.03,Ac:227.03,Th:232.0381,Pa:231.03588,U:238.02891,Np:237.05,Pu:244.06,Am:243.06,Cm:247.07,Bk:247.07,Cf:251.08,Es:252.08,Fm:257.1,Md:258.1,No:259.1,Lr:262.11,Rf:261.11,Db:262.11,Sg:266.12,Bh:264.12,Hs:269.13,Mt:268.14};const bioData=Object.freeze(Object.defineProperty({__proto__:null,ambiguous_dna_complement,ambiguous_dna_letters,ambiguous_dna_values,ambiguous_rna_complement,ambiguous_rna_letters,ambiguous_rna_values,atom_weights,extended_dna_letters,extended_protein_letters,extended_protein_values,monoisotopic_protein_weights,monoisotopic_unambiguous_dna_weights,monoisotopic_unambiguous_rna_weights,protein_letters,protein_letters_1to3,protein_weights,unambiguous_dna_letters,unambiguous_dna_weights,unambiguous_rna_letters,unambiguous_rna_weights},Symbol.toStringTag,{value:"Module"}));const aminoAcidToDegenerateDnaMap={"-":"---",".":"...","*":"trr",a:"gcn",b:"ray",c:"tgy",d:"gay",e:"gar",f:"tty",g:"ggn",h:"cay",i:"ath",j:"htn",k:"aar",l:"ytn",m:"atg",n:"aay",o:"tag",p:"ccn",q:"car",r:"mgn",s:"wsn",t:"acn",u:"tga",v:"gtn",w:"tgg",x:"nnn",y:"tay",z:"sar"};function splitRangeIntoTwoPartsIfItIsCircular(range,sequenceLength){if(sequenceLength!==0){sequenceLength=sequenceLength||Infinity}const ranges=[];if(range.start>range.end){ranges.push({start:0,end:range.end,type:"end"});ranges.push({start:range.start,end:sequenceLength-1,type:"beginning"})}else{ranges.push({start:range.start,end:range.end,type:"beginningAndEnd"})}return ranges}__name(splitRangeIntoTwoPartsIfItIsCircular,"splitRangeIntoTwoPartsIfItIsCircular");function getOverlapOfNonCircularRanges(rangeA,rangeB){if(rangeA.start<rangeB.start){if(rangeA.end<rangeB.start);else{if(rangeA.end<rangeB.end){return{start:rangeB.start,end:rangeA.end}}else{return{start:rangeB.start,end:rangeB.end}}}}else{if(rangeA.start>rangeB.end);else{if(rangeA.end<rangeB.end){return{start:rangeA.start,end:rangeA.end}}else{return{start:rangeA.start,end:rangeB.end}}}}}__name(getOverlapOfNonCircularRanges,"getOverlapOfNonCircularRanges");function getOverlapsOfPotentiallyCircularRanges(rangeA,rangeB,maxRangeLength,joinIfPossible){const normalizedRangeA=splitRangeIntoTwoPartsIfItIsCircular(rangeA,maxRangeLength);const normalizedRangeB=splitRangeIntoTwoPartsIfItIsCircular(rangeB,maxRangeLength);let overlaps=[];normalizedRangeA.forEach(function(nonCircularRangeA,iA){normalizedRangeB.forEach(function(nonCircularRangeB,iB){const overlap=getOverlapOfNonCircularRanges(nonCircularRangeA,nonCircularRangeB);if(overlap){overlaps.push(overlap)}})});if(joinIfPossible&&normalizedRangeA.length===2&&normalizedRangeB.length===2&&maxRangeLength){const joinedOverlap={};overlaps=lodashExports.flatMap(overlaps,(o,i)=>{if(o.start===0){joinedOverlap.end=o.end;return[]}else if(o.end===maxRangeLength-1){joinedOverlap.start=o.start;return[]}});overlaps.push(joinedOverlap)}return overlaps}__name(getOverlapsOfPotentiallyCircularRanges,"getOverlapsOfPotentiallyCircularRanges");function trimNonCicularRangeByAnotherNonCircularRange(rangeToBeTrimmed,trimmingRange){let outputTrimmedRange;if(!rangeToBeTrimmed){return outputTrimmedRange}if(rangeToBeTrimmed.start<trimmingRange.start){if(rangeToBeTrimmed.end<trimmingRange.start){outputTrimmedRange={start:rangeToBeTrimmed.start,end:rangeToBeTrimmed.end}}else{if(rangeToBeTrimmed.end>trimmingRange.end){outputTrimmedRange={start:rangeToBeTrimmed.start,end:rangeToBeTrimmed.end}}else{outputTrimmedRange={start:rangeToBeTrimmed.start,end:trimmingRange.start-1}}}}else{if(rangeToBeTrimmed.end<=trimmingRange.end);else{if(rangeToBeTrimmed.start>trimmingRange.end){outputTrimmedRange={end:rangeToBeTrimmed.end,start:rangeToBeTrimmed.start}}else{outputTrimmedRange={end:rangeToBeTrimmed.end,start:trimmingRange.end+1}}}}return outputTrimmedRange}__name(trimNonCicularRangeByAnotherNonCircularRange,"trimNonCicularRangeByAnotherNonCircularRange");function trimRangeByAnotherRange(rangeToBeTrimmed,trimmingRange,sequenceLength){if(!rangeToBeTrimmed||!trimmingRange){console.warn("invalid range input");return null}let position;for(position of[rangeToBeTrimmed.start,rangeToBeTrimmed.end,trimmingRange.start,trimmingRange.end]){if(position<0||!position&&position!==0){console.warn("invalid range input");return null}}const overlaps=getOverlapsOfPotentiallyCircularRanges(rangeToBeTrimmed,trimmingRange,sequenceLength);if(!overlaps.length){return rangeToBeTrimmed}const splitRangesToBeTrimmed=splitRangeIntoTwoPartsIfItIsCircular(rangeToBeTrimmed,sequenceLength);splitRangesToBeTrimmed.forEach(function(nonCircularRangeToBeTrimmed,index2){overlaps.forEach(function(overlap){if(nonCircularRangeToBeTrimmed){nonCircularRangeToBeTrimmed=trimNonCicularRangeByAnotherNonCircularRange(nonCircularRangeToBeTrimmed,overlap)}});splitRangesToBeTrimmed[index2]=nonCircularRangeToBeTrimmed});const outputSplitRanges=splitRangesToBeTrimmed.filter(function(trimmedRange){if(trimmedRange){return true}return false});let outputTrimmedRange;if(outputSplitRanges.length<0);else if(outputSplitRanges.length===1){outputTrimmedRange=outputSplitRanges[0]}else if(outputSplitRanges.length===2){if(outputSplitRanges[0].start<outputSplitRanges[1].start){outputTrimmedRange={start:outputSplitRanges[1].start,end:outputSplitRanges[0].end}}else{outputTrimmedRange={start:outputSplitRanges[0].start,end:outputSplitRanges[1].end}}}if(outputTrimmedRange){return lodashExports.extend({},rangeToBeTrimmed,{start:outputTrimmedRange.start,end:outputTrimmedRange.end})}}__name(trimRangeByAnotherRange,"trimRangeByAnotherRange");function adjustRangeToDeletionOfAnotherRange(rangeToBeAdjusted,anotherRange,maxLength){const trimmedRange=trimRangeByAnotherRange(rangeToBeAdjusted,anotherRange,maxLength);if(trimmedRange){const nonCircularDeletionRanges=splitRangeIntoTwoPartsIfItIsCircular(anotherRange,maxLength);nonCircularDeletionRanges.forEach(function(nonCircularDeletionRange){const deletionLength=nonCircularDeletionRange.end-nonCircularDeletionRange.start+1;if(trimmedRange.start>trimmedRange.end){if(nonCircularDeletionRange.start<trimmedRange.end){trimmedRange.start-=deletionLength;trimmedRange.end-=deletionLength}else if(nonCircularDeletionRange.start<trimmedRange.start){trimmedRange.start-=deletionLength}else;}else{if(nonCircularDeletionRange.start<trimmedRange.start){trimmedRange.start-=deletionLength;trimmedRange.end-=deletionLength}else if(nonCircularDeletionRange.start<trimmedRange.end){trimmedRange.end-=deletionLength}else;}})}return trimmedRange}__name(adjustRangeToDeletionOfAnotherRange,"adjustRangeToDeletionOfAnotherRange");function adjustRangeToInsert(rangeToBeAdjusted,insertStart,insertLength){const newRange=lodashExports.assign({},rangeToBeAdjusted);if(rangeToBeAdjusted.start>rangeToBeAdjusted.end){if(rangeToBeAdjusted.end>=insertStart){newRange.start+=insertLength;newRange.end+=insertLength}else if(rangeToBeAdjusted.start>=insertStart){newRange.start+=insertLength}}else{if(rangeToBeAdjusted.start>=insertStart){newRange.start+=insertLength;newRange.end+=insertLength}else if(rangeToBeAdjusted.end>=insertStart){newRange.end+=insertLength}}return newRange}__name(adjustRangeToInsert,"adjustRangeToInsert");function checkIfNonCircularRangesOverlap(range,comparisonRange){if(range.start<comparisonRange.start){if(range.end<comparisonRange.start){return false}else{return true}}else{if(range.start>comparisonRange.end){return false}else{return true}}}__name(checkIfNonCircularRangesOverlap,"checkIfNonCircularRangesOverlap");function checkIfPotentiallyCircularRangesOverlap(range,comparisonRange){return splitRangeIntoTwoPartsIfItIsCircular(range,Infinity).some(function(splitRange){return splitRangeIntoTwoPartsIfItIsCircular(comparisonRange,Infinity).some(function(splitComparisonRange){return checkIfNonCircularRangesOverlap(splitRange,splitComparisonRange)})})}__name(checkIfPotentiallyCircularRangesOverlap,"checkIfPotentiallyCircularRangesOverlap");function collapseOverlapsGeneratedFromRangeComparisonIfPossible(overlaps,sequenceLength,optionalOriginalRange){const originalRangeLinear=optionalOriginalRange&&optionalOriginalRange.start<=optionalOriginalRange.end;if(overlaps.length===1||overlaps.length===0){return overlaps}else if(overlaps.length===2){if(overlaps[0].start===0&&overlaps[1].end+1===sequenceLength&&!originalRangeLinear){return[{start:overlaps[1].start,end:overlaps[0].end}]}else if(overlaps[1].start===0&&overlaps[0].end+1===sequenceLength&&!originalRangeLinear){return[{start:overlaps[0].start,end:overlaps[1].end}]}else{return overlaps}}else if(overlaps.length===3){const firstOverlap=overlaps[0];const secondOverlap=overlaps[1];const thirdOverlap=overlaps[2];let collapsedOverlaps=collapseOverlapsGeneratedFromRangeComparisonIfPossible([firstOverlap,secondOverlap],sequenceLength,optionalOriginalRange);if(collapsedOverlaps.length===1){collapsedOverlaps.push(thirdOverlap);return collapsedOverlaps}else{collapsedOverlaps=collapseOverlapsGeneratedFromRangeComparisonIfPossible([firstOverlap,thirdOverlap],sequenceLength,optionalOriginalRange);if(collapsedOverlaps.length===1){collapsedOverlaps.push(secondOverlap);return collapsedOverlaps}else{collapsedOverlaps=collapseOverlapsGeneratedFromRangeComparisonIfPossible([secondOverlap,thirdOverlap],sequenceLength,optionalOriginalRange);if(collapsedOverlaps.length===1){collapsedOverlaps.push(firstOverlap);return collapsedOverlaps}else{return overlaps}}}}}__name(collapseOverlapsGeneratedFromRangeComparisonIfPossible,"collapseOverlapsGeneratedFromRangeComparisonIfPossible");function provideInclusiveOptions(funToWrap){return function(){const args=Array.prototype.slice.call(arguments);const options=args[args.length-1];if(options&&(options.inclusive1BasedEnd||options.inclusive1BasedStart)){args.forEach(function(arg,index2){if(arg&&arg.start>-1&&options.inclusive1BasedStart){args[index2]=lodashExports.assign(arg,{start:arg.start-1})}if(arg&&arg.end>-1&&options.inclusive1BasedEnd){args[index2]=lodashExports.assign(arg,{end:arg.end-1})}})}let returnVal=funToWrap.apply(this,args);if(returnVal&&returnVal.start>-1&&options&&options.inclusive1BasedStart){returnVal=lodashExports.assign(returnVal,{start:returnVal.start+1})}if(returnVal&&returnVal.end>-1&&options&&options.inclusive1BasedEnd){returnVal=lodashExports.assign(returnVal,{end:returnVal.end+1})}return returnVal}}__name(provideInclusiveOptions,"provideInclusiveOptions");const getRangeLength=provideInclusiveOptions(getRangeLength$1);function getRangeLength$1(range,rangeMax){let toRet;if(range.end<range.start){toRet=rangeMax-range.start+range.end+1}else{toRet=range.end-range.start+1}if(range.overlapsSelf&&rangeMax){toRet+=rangeMax}return toRet}__name(getRangeLength$1,"getRangeLength$1");function isRangeWithinRange(rangeToCheck,containingRange,maxLength){let ranges=trimRangeByAnotherRange(rangeToCheck,containingRange,maxLength);if(ranges===null)return false;return!ranges}__name(isRangeWithinRange,"isRangeWithinRange");function isPositionWithinRange(position,range,sequenceLength,includeStartEdge,includeEndEdge){const ranges=splitRangeIntoTwoPartsIfItIsCircular(range,sequenceLength);const positionFits=ranges.some(function(range2){if(includeStartEdge?position<range2.start:position<=range2.start){return false}else{if(includeEndEdge?position<=range2.end+1:position<=range2.end){return true}else{return false}}});return positionFits}__name(isPositionWithinRange,"isPositionWithinRange");function normalizePositionByRangeLength(pPosition,sequenceLength,isInBetweenPositions){let position=pPosition;if(position<0){position+=sequenceLength}else if(position+(isInBetweenPositions?0:1)>sequenceLength){position-=sequenceLength}return position<0?0:position>sequenceLength-(isInBetweenPositions?0:1)?sequenceLength-(isInBetweenPositions?0:1):position}__name(normalizePositionByRangeLength,"normalizePositionByRangeLength");function normalizeRange(range,sequenceLength){return lodashExports.assign({},range,{start:normalizePositionByRangeLength(range.start,sequenceLength),end:normalizePositionByRangeLength(range.end,sequenceLength)})}__name(normalizeRange,"normalizeRange");function expandOrContractRangeByLength(range,shiftBy,shiftStart,sequenceLength){const rangeToReturn=lodashExports.clone(range);if(shiftStart){rangeToReturn.start-=shiftBy}else{rangeToReturn.end+=shiftBy}return normalizeRange(rangeToReturn,sequenceLength)}__name(expandOrContractRangeByLength,"expandOrContractRangeByLength");function translateRange(rangeToBeAdjusted,translateBy,rangeLength){return lodashExports.assign({},rangeToBeAdjusted,{start:normalizePositionByRangeLength(rangeToBeAdjusted.start+translateBy,rangeLength),end:normalizePositionByRangeLength(rangeToBeAdjusted.end+translateBy,rangeLength)})}__name(translateRange,"translateRange");function flipRelativeRange(innerRange,outerRange,sequenceLength,options){const isFullyContained=isRangeWithinRange(innerRange,outerRange,sequenceLength);if(isFullyContained){return flipFullyContainedRange(innerRange,outerRange,sequenceLength)}else{return flipNonFullyContainedRange(innerRange,outerRange,sequenceLength)}}__name(flipRelativeRange,"flipRelativeRange");function flipNonFullyContainedRange(innerRange,outerRange,sequenceLength,options){const outerFullyContained=isRangeWithinRange(outerRange,innerRange,sequenceLength);let flippedInnerRange;if(outerFullyContained){const expandBy1=getRangeLength({start:innerRange.start,end:outerRange.start},sequenceLength)-1;flippedInnerRange=expandOrContractRangeByLength(outerRange,expandBy1,false,sequenceLength);const expandBy2=getRangeLength({end:innerRange.end,start:outerRange.end},sequenceLength)-1;flippedInnerRange=expandOrContractRangeByLength(flippedInnerRange,expandBy2,true,sequenceLength)}else{const overlaps=getOverlapsOfPotentiallyCircularRanges(innerRange,outerRange,sequenceLength);if(overlaps.length>=1){let overlapExtendsForward;const firstOverlap=overlaps[0];overlapExtendsForward=firstOverlap.start!==outerRange.start;const flippedTruncatedInner=flipFullyContainedRange(firstOverlap,outerRange,sequenceLength);const lengthToExtend=getRangeLength(innerRange,sequenceLength)-getRangeLength(flippedTruncatedInner,sequenceLength);flippedInnerRange=expandOrContractRangeByLength(flippedTruncatedInner,lengthToExtend,overlapExtendsForward,sequenceLength)}else{throw new Error("This case (relative ranges that do not overlap) is unsupported! ")}}return flippedInnerRange}__name(flipNonFullyContainedRange,"flipNonFullyContainedRange");function flipFullyContainedRange(innerRange,outerRange,sequenceLength,options){const translateBy=-outerRange.start;const translatedOuterRange=translateRange(outerRange,translateBy,sequenceLength);const translatedInnerRange=translateRange(innerRange,translateBy,sequenceLength);const translatedFlippedInnerRange=flipNonOriginSpanningContainedRange(translatedInnerRange,translatedOuterRange,sequenceLength);const flippedInnerRange=translateRange(translatedFlippedInnerRange,-translateBy,sequenceLength);return flippedInnerRange}__name(flipFullyContainedRange,"flipFullyContainedRange");function flipNonOriginSpanningContainedRange(innerRange,outerRange,sequenceLength){const offsetFromStart=innerRange.start-outerRange.start;const newInnerEnd=outerRange.end-offsetFromStart;const innerRangeLength=getRangeLength(innerRange,sequenceLength);return{end:newInnerEnd,start:newInnerEnd-(innerRangeLength-1)}}__name(flipNonOriginSpanningContainedRange,"flipNonOriginSpanningContainedRange");function generateRandomRange(minStart,maxEnd,maxLength){const start=getRandomInt$1(minStart,maxEnd);let end;if(maxLength){end=normalizePositionByRangeLength(getRandomInt$1(start,start+maxLength),maxEnd)}else{end=getRandomInt$1(minStart,maxEnd)}return{start,end}}__name(generateRandomRange,"generateRandomRange");function getRandomInt$1(min,max){return Math.floor(Math.random()*(max-min))+min}__name(getRandomInt$1,"getRandomInt$1");function getSequenceWithinRange(range,sequence){if(range.start<0||range.end<0)return"";if(range.start>range.end){let subSequence=sequence.slice(range.start,sequence.length);if(typeof subSequence==="string"){subSequence+=sequence.slice(0,range.end+1)}else{subSequence=subSequence.concat(sequence.slice(0,range.end+1))}return subSequence}else{return sequence.slice(range.start,range.end+1)}}__name(getSequenceWithinRange,"getSequenceWithinRange");function getShortestDistanceBetweenTwoPositions(position1,position2,sequenceLength){if(position1<position2){const position1Holder=position1;position1=position2;position2=position1Holder}const d1=position1-position2;const d2=sequenceLength-position1+position2;return Math.min(d1,d2)}__name(getShortestDistanceBetweenTwoPositions,"getShortestDistanceBetweenTwoPositions");function getYOffsetForPotentiallyCircularRange(range,YOffsetLevelsWithRanges,assignYOffsetToRange){let yOffset=[];const openYOffsetFound=YOffsetLevelsWithRanges.some(function(rangesAlreadyAddedToYOffset,index2){const rangeBlocked=rangesAlreadyAddedToYOffset.some(function(comparisonRange){return checkIfPotentiallyCircularRangesOverlap(range,comparisonRange)});if(!rangeBlocked){yOffset=index2;if(assignYOffsetToRange)range.yOffset=index2;rangesAlreadyAddedToYOffset.push(range);return true}});if(!openYOffsetFound){yOffset=YOffsetLevelsWithRanges.length;if(assignYOffsetToRange)range.yOffset=YOffsetLevelsWithRanges.length}return yOffset}__name(getYOffsetForPotentiallyCircularRange,"getYOffsetForPotentiallyCircularRange");function getYOffsetsForPotentiallyCircularRanges(ranges,assignYOffsetToRange){const yOffsets=[];let maxYOffset=0;const yOffsetLevels=[];ranges.forEach(function(range){const yOffset=getYOffsetForPotentiallyCircularRange(range,yOffsetLevels,assignYOffsetToRange);yOffsets.push(yOffset);if(yOffset>maxYOffset){maxYOffset=yOffset}range.yOffset=yOffset;if(!yOffsetLevels[yOffset])yOffsetLevels[yOffset]=[];yOffsetLevels[yOffset].push(range)});return{yOffsets,maxYOffset}}__name(getYOffsetsForPotentiallyCircularRanges,"getYOffsetsForPotentiallyCircularRanges");const invertRange=provideInclusiveOptions(invertRange$1);function invertRange$1(rangeOrCaret,rangeMax){if(rangeOrCaret.start>-1){const start=rangeOrCaret.end+1;const end=rangeOrCaret.start-1;return{start:normalizePositionByRangeLength(start,rangeMax,false),end:normalizePositionByRangeLength(end,rangeMax,false)}}else{if(rangeOrCaret>-1){return{start:normalizePositionByRangeLength(rangeOrCaret,rangeMax,false),end:normalizePositionByRangeLength(rangeOrCaret-1,rangeMax,false)}}}}__name(invertRange$1,"invertRange$1");function isPositionCloserToRangeStartThanRangeEnd(position,range,maxLength){const distanceFromStart=getShortestDistanceBetweenTwoPositions(range.start,position,maxLength);const distanceFromEnd=getShortestDistanceBetweenTwoPositions(range.end,position,maxLength);return distanceFromStart<=distanceFromEnd}__name(isPositionCloserToRangeStartThanRangeEnd,"isPositionCloserToRangeStartThanRangeEnd");function modulatePositionByRange(position,range){let returnVal=position;if(position<range.start){returnVal=range.end-(range.start-(position+1))}else if(position>range.end){returnVal=range.start+(position-range.end-1)}return returnVal}__name(modulatePositionByRange,"modulatePositionByRange");const modulateRangeBySequenceLength=provideInclusiveOptions(modulateRangeBySequenceLength$1);function modulateRangeBySequenceLength$1(range,seqLen){return lodashExports.assign(range,{start:normalizePositionByRangeLength(range.start,seqLen),end:normalizePositionByRangeLength(range.end,seqLen)})}__name(modulateRangeBySequenceLength$1,"modulateRangeBySequenceLength$1");function normalizePositionByRangeLength1Based(position,sequenceLength){return modulatePositionByRange(position,{start:1,end:sequenceLength})}__name(normalizePositionByRangeLength1Based,"normalizePositionByRangeLength1Based");function reversePositionInRange(position,rangeLength,isInBetweenPositions){return rangeLength-position-(isInBetweenPositions?0:1)}__name(reversePositionInRange,"reversePositionInRange");function zeroSubrangeByContainerRange(subRange,containerRange,sequenceLength){const trimmedSubRange=trimRangeByAnotherRange(subRange,containerRange,sequenceLength);if(trimmedSubRange){throw new Error("subRange must be fully contained by containerRange! Otherwise this function does not make sense")}const newSubrange={};newSubrange.start=subRange.start-containerRange.start;newSubrange.end=subRange.end-containerRange.start;if(newSubrange.start<0){newSubrange.start+=sequenceLength}if(newSubrange.end<0){newSubrange.end+=sequenceLength}return newSubrange}__name(zeroSubrangeByContainerRange,"zeroSubrangeByContainerRange");function adjustRangeToRotation(rangeToBeAdjusted,rotateTo=0,rangeLength){const mod=rangeLength?modulo:lodashExports.identity;const newRange=lodashExports.assign({},rangeToBeAdjusted,{start:mod(rangeToBeAdjusted.start-(rotateTo||0),rangeLength),end:mod(rangeToBeAdjusted.end-(rotateTo||0),rangeLength)});return newRange}__name(adjustRangeToRotation,"adjustRangeToRotation");function modulo(n,m){return(n%m+m)%m}__name(modulo,"modulo");function getZeroedRangeOverlaps(annotation,selection,sequenceLength){const overlaps=collapseOverlapsGeneratedFromRangeComparisonIfPossible(getOverlapsOfPotentiallyCircularRanges(annotation,selection,sequenceLength),sequenceLength,annotation);const zeroedOverlaps=overlaps.map(overlap=>{return zeroSubrangeByContainerRange(overlap,{start:selection.start,end:normalizePositionByRangeLength(selection.start-1,sequenceLength)},sequenceLength)});return zeroedOverlaps}__name(getZeroedRangeOverlaps,"getZeroedRangeOverlaps");const DNAComplementMap={".":".",a:"t",t:"a",u:"a",c:"g",g:"c",A:"T",T:"A",U:"A",C:"G",G:"C",r:"y",R:"Y",y:"r",Y:"R",d:"h",D:"H",h:"d",H:"D",k:"m",K:"M",m:"k",M:"K",v:"b",V:"B",b:"v",B:"V"};function getReverseComplementSequenceString(sequence){let reverseComplementSequenceString="";for(let i=sequence.length-1;i>=0;i--){let revChar=DNAComplementMap[sequence[i]];if(!revChar){revChar=sequence[i]}reverseComplementSequenceString+=revChar}return reverseComplementSequenceString}__name(getReverseComplementSequenceString,"getReverseComplementSequenceString");function autoAnnotate({seqsToAnnotateById,annotationsToCheckById,compareName,warnIfMoreThan}){const annotationsToAddBySeqId={};lodashExports.forEach(annotationsToCheckById,ann=>{const reg=new RegExp(ann.sequence,"gi");lodashExports.forEach(lodashExports.omitBy(seqsToAnnotateById,s=>!s.sequence.length),({circular,sequence},id)=>{function getMatches({seqToMatchAgainst,isReverse,seqLen:seqLen2}){let match;let lastMatch;try{while(match=reg.exec(seqToMatchAgainst)){const{index:matchStart,0:matchSeq}=match;if(matchStart>=seqLen2)return;const matchEnd=matchStart+matchSeq.length;if(lastMatch){if(matchStart>lastMatch.start&&matchEnd<=lastMatch.end){reg.lastIndex=match.index+1;continue}}lastMatch={start:matchStart,end:matchEnd};const range={start:matchStart,end:normalizePositionByRangeLength(matchEnd-1,seqLen2)};if(!annotationsToAddBySeqId[id])annotationsToAddBySeqId[id]=[];annotationsToAddBySeqId[id].push(__spreadProps(__spreadValues({},isReverse?{start:reversePositionInRange(range.end,seqLen2),end:reversePositionInRange(range.start,seqLen2)}:range),{strand:isReverse?-1:1,id:ann.id}));reg.lastIndex=match.index+1}}catch(error){console.error(`error:`,error)}}__name(getMatches,"getMatches");const seqLen=sequence.length;const revSeq=getReverseComplementSequenceString(sequence);getMatches({seqLen,seqToMatchAgainst:circular?sequence+sequence:sequence});getMatches({seqLen,isReverse:true,seqToMatchAgainst:circular?revSeq+revSeq:revSeq})})});const toReturn={};lodashExports.forEach(annotationsToAddBySeqId,(anns,id)=>{const origSeq=seqsToAnnotateById[id];const alreadyExistingAnnsByStartEnd={};lodashExports.forEach(origSeq.annotations,ann=>{alreadyExistingAnnsByStartEnd[getStartEndStr(ann,{compareName})]=ann});const warningCounter={};const toAdd=anns.filter(ann=>{const alreadyExistingAnn=alreadyExistingAnnsByStartEnd[getStartEndStr(ann,{compareName})];if(alreadyExistingAnn)return false;if(warnIfMoreThan){warningCounter[ann.id]=(warningCounter[ann.id]||0)+1}return true}).sort((a,b)=>a.start-b.start);if(toAdd.length){toReturn[id]=toAdd}warnIfMoreThan&&lodashExports.forEach(warningCounter,(num,annId)=>{if(num>warnIfMoreThan){toReturn.__more_than_warnings=toReturn.__more_than_warnings||{};toReturn.__more_than_warnings[id]=toReturn.__more_than_warnings[id]||[];toReturn.__more_than_warnings[id].push(annId)}})});return toReturn}__name(autoAnnotate,"autoAnnotate");function getStartEndStr({start,end,name,strand,forward},{compareName}){const isReverse=strand===-1||forward===false;return`${start}-${end}-${isReverse?"rev":"for"}-${compareName?name:""}`}__name(getStartEndStr,"getStartEndStr");function convertApELikeRegexToRegex(regString=""){let newstr="";let rightOfCaretHolder="";let afterRightCaretHolder="";let beforeRightCaret="";let prevBp;let hitLeftCaret;let hitRightCaret;for(const bp of regString.replace("(","").replace(")","")){let maybeHandleRightCaret=function(justAdded){if(hitRightCaret){rightOfCaretHolder+=justAdded;afterRightCaretHolder=`${rightOfCaretHolder}${afterRightCaretHolder.length?"|":""}${afterRightCaretHolder}`}};__name(maybeHandleRightCaret,"maybeHandleRightCaret");const ambigVal=ambiguous_dna_values[bp.toUpperCase()];if(ambigVal&&ambigVal.length>1){let valToUse;if(ambigVal.length===4){valToUse="."}else{valToUse=`[${ambigVal}]`}newstr+=valToUse;maybeHandleRightCaret(valToUse);continue}if(bp==="#"){if(hitRightCaret)throw new Error("Error converting regex");const valToUse=prevBp?`[^${prevBp}]*?`:`.*?`;newstr+=valToUse;maybeHandleRightCaret(valToUse);continue}if(bp==="<"){if(hitRightCaret)throw new Error("Error converting to regex");if(hitLeftCaret)throw new Error("Error converting to regex");let holder="";let stringToAdd="";let isGroupClosed=true;let closingBraceHit;const groups=[];for(let index2=0;index2<newstr.length;index2++){const char=newstr[index2];const nextChar=newstr[index2+1];if(char==="["){isGroupClosed=false}else if(char==="]"||closingBraceHit){closingBraceHit=true;if(ambiguous_dna_values[nextChar]||nextChar==="["){isGroupClosed=true;closingBraceHit=false}}holder+=char;if(isGroupClosed){groups.push(holder);holder=""}}let concattedEls="";groups.reverse();groups.forEach(g=>{concattedEls=g+concattedEls;stringToAdd=`${concattedEls}${stringToAdd.length?"|":""}${stringToAdd}`});newstr=`(${stringToAdd})?`;hitLeftCaret=true;continue}if(bp===">"){if(hitRightCaret)throw new Error("Error converting regex");hitRightCaret=true;beforeRightCaret=newstr;continue}newstr+=bp;maybeHandleRightCaret(bp);prevBp=bp}if(hitRightCaret){newstr=`${beforeRightCaret}(${afterRightCaretHolder})?`}return newstr}__name(convertApELikeRegexToRegex,"convertApELikeRegexToRegex");function convertProteinSeqToDNAIupac(sequence){let toRet="";let l;for(l of sequence){const degenDna=aminoAcidToDegenerateDnaMap[l.toLowerCase()];if(degenDna){toRet+=degenDna}else{toRet+=l}}return toRet}__name(convertProteinSeqToDNAIupac,"convertProteinSeqToDNAIupac");const genbankFeatureTypes=[{name:"-10_signal",color:"#4ECDC4"},{name:"-35_signal",color:"#F7FFF7"},{name:"3'clip",color:"#FF6B6B"},{name:"3'UTR",color:"#FFE66D"},{name:"5'clip",color:"#3E517A"},{name:"5'UTR",color:"#BBBBBB"},{name:"D-loop",color:"#F13C73"},{name:"assembly_gap",color:"#DE9151"},{name:"centromere",color:"#F34213"},{name:"Het",color:"#BC5D2E"},{name:"mobile_element",color:"#6DB1BF"},{name:"ncRNA",color:"#FFEAEC"},{name:"proprotein",color:"#F39A9D"},{name:"regulatory",color:"#3F6C51"},{name:"SecStr",color:"#7B4B94"},{name:"Site",color:"#7D82B8"},{name:"telomere",color:"DE9151"},{name:"tmRNA",color:"#B7E3CC"},{name:"unsure",color:"#C4FFB2"},{name:"V_segment",color:"#D6F7A3"},{name:"allele",color:"#D86D6D"},{name:"attenuator",color:"#6B7F9C"},{name:"C_region",color:"#B5D89D"},{name:"CAAT_signal",color:"#E9CD98"},{name:"CDS",color:"#EF6500"},{name:"conserved",color:"#A3A5F0"},{name:"D_segment",color:"#C060F7"},{name:"default",color:"#CCCCCC"},{name:"enhancer",color:"#38F872"},{name:"exon",color:"#95F844"},{name:"gap",color:"#F7D43C"},{name:"GC_signal",color:"#861F1F"},{name:"gene",color:"#684E27"},{name:"iDNA",color:"#A59B41"},{name:"intron",color:"#52963E"},{name:"J_region",color:"#369283"},{name:"LTR",color:"#31748F"},{name:"m_rna",color:"#FFFF00"},{name:"mat_peptide",color:"#353E8F"},{name:"misc_binding",color:"#006FEF"},{name:"misc_difference",color:"#5A368A"},{name:"misc_feature",color:"#006FEF"},{name:"misc_marker",color:"#8DCEB1"},{name:"misc_part",color:"#006FEF"},{name:"misc_recomb",color:"#DD97B4"},{name:"misc_RNA",color:"#BD0101"},{name:"misc_signal",color:"#FF9A04"},{name:"misc_structure",color:"#B3FF00"},{name:"modified_base",color:"#00F7FF"},{name:"mRNA",color:"#FFD900"},{name:"N_region",color:"#AE00FF"},{name:"old_sequence",color:"#F0A7FF"},{name:"operator",color:"#63004D"},{name:"operon",color:"#000653"},{name:"oriT",color:"#580000"},{name:"plasmid",color:"#00635E"},{name:"polyA_signal",color:"#BBBBBB"},{name:"polyA_site",color:"#003328"},{name:"precursor_RNA",color:"#443200"},{name:"prim_transcript",color:"#665E4C"},{name:"primer_bind",color:"#53d969"},{name:"promoter",color:"#31B440"},{name:"protein_bind",color:"#2E2E2E"},{name:"protein_domain",color:"#4D4B4B"},{name:"protein",color:"#696969"},{name:"RBS",color:"#BDFFCB"},{name:"rep_origin",color:"#878787"},{name:"repeat_region",color:"#966363"},{name:"repeat_unit",color:"#A16D8D"},{name:"rRNA",color:"#9BF0FF"},{name:"s_mutation",color:"#70A2FF"},{name:"S_region",color:"#FF74A9"},{name:"satellite",color:"#164E64"},{name:"scRNA",color:"#A057FF"},{name:"sig_peptide",color:"#2FFF8D"},{name:"snoRNA",color:"#296B14"},{name:"snRNA",color:"#A16249"},{name:"source",color:"#0B17BD"},{name:"start",color:"#D6A336"},{name:"stem_loop",color:"#67069E"},{name:"stop",color:"#D44FC9"},{name:"STS",color:"#597FE7"},{name:"tag",color:"#E419DA"},{name:"TATA_signal",color:"#EB2B2B"},{name:"terminator",color:"#F51600"},{name:"transit_peptide",color:"#24D491"},{name:"transposon",color:"#B6E436"},{name:"tRNA",color:"#D1456F"},{name:"V_region",color:"#7B5EE7"},{name:"variation",color:"#2EE455"}];const getMergedFeatureMap=__name(()=>{const keyedGBFeats=lodashExports.keyBy(genbankFeatureTypes.map(f=>__spreadProps(__spreadValues({},f),{isGenbankStandardType:true})),"name");let featureOverrides=typeof window!=="undefined"&&lodashExports.get(window,"tg_featureTypeOverrides")||typeof global!=="undefined"&&lodashExports.get(global,"tg_featureTypeOverrides");featureOverrides=featureOverrides||[];featureOverrides=featureOverrides.map(fo=>{const originalGenbankFeat=keyedGBFeats[fo.name];return __spreadValues(__spreadValues(__spreadValues({},originalGenbankFeat),fo),originalGenbankFeat?{isOverridden:true}:{isCustomType:true})});featureOverrides=lodashExports.keyBy(featureOverrides,"name");return __spreadValues(__spreadValues({},keyedGBFeats),featureOverrides)},"getMergedFeatureMap");const getFeatureToColorMap=__name(({includeHidden}={})=>{const toRet={};lodashExports.filter(getMergedFeatureMap(),f=>includeHidden?true:!f.isHidden).forEach(f=>{toRet[f.name]=f.color});return toRet},"getFeatureToColorMap");const getFeatureTypes=__name(({includeHidden}={})=>lodashExports.filter(getMergedFeatureMap(),f=>includeHidden?true:!f.isHidden).map(f=>f.name),"getFeatureTypes");var MACHINE_ID=Math.floor(Math.random()*16777215);var index=ObjectID.index=parseInt(Math.random()*16777215,10);var pid=(typeof process==="undefined"||typeof process.pid!=="number"?Math.floor(Math.random()*1e5):process.pid)%65535;var isBuffer=__name(function(obj){return!!(obj!=null&&obj.constructor&&typeof obj.constructor.isBuffer==="function"&&obj.constructor.isBuffer(obj))},"isBuffer");function ObjectID(arg){if(!(this instanceof ObjectID))return new ObjectID(arg);if(arg&&(arg instanceof ObjectID||arg._bsontype==="ObjectID"))return arg;var buf;if(isBuffer(arg)||Array.isArray(arg)&&arg.length===12){buf=Array.prototype.slice.call(arg)}else if(typeof arg==="string"){if(arg.length!==12&&!ObjectID.isValid(arg))throw new Error("Argument passed in must be a single String of 12 bytes or a string of 24 hex characters");buf=buffer(arg)}else if(/number|undefined/.test(typeof arg)){buf=buffer(generate(arg))}Object.defineProperty(this,"id",{enumerable:true,get:function(){return String.fromCharCode.apply(this,buf)}});Object.defineProperty(this,"str",{get:function(){return buf.map(hex.bind(this,2)).join("")}})}__name(ObjectID,"ObjectID");var objectid=ObjectID;ObjectID.generate=generate;ObjectID.default=ObjectID;ObjectID.createFromTime=function(time){time=parseInt(time,10)%4294967295;return new ObjectID(hex(8,time)+"0000000000000000")};ObjectID.createFromHexString=function(hexString){if(!ObjectID.isValid(hexString))throw new Error("Invalid ObjectID hex string");return new ObjectID(hexString)};ObjectID.isValid=function(objectid2){if(!objectid2||typeof objectid2!=="string"&&(typeof objectid2!=="object"||Array.isArray(objectid2)||typeof objectid2.toString!=="function"))return false;return/^[0-9A-F]{24}$/i.test(objectid2.toString())};ObjectID.setMachineID=function(arg){var machineID;if(typeof arg==="string"){machineID=parseInt(arg,16);if(isNaN(machineID)){arg=("000000"+arg).substr(-7,6);machineID="";for(var i=0;i<6;i++){machineID+=arg.charCodeAt(i)}}}else if(/number|undefined/.test(typeof arg)){machineID=arg|0}MACHINE_ID=machineID&16777215};ObjectID.getMachineID=function(){return MACHINE_ID};ObjectID.prototype={_bsontype:"ObjectID",constructor:ObjectID,toHexString:function(){return this.str},equals:function(other){return!!other&&this.str===other.toString()},getTimestamp:function(){return new Date(parseInt(this.str.substr(0,8),16)*1e3)}};function next(){return index=(index+1)%16777215}__name(next,"next");function generate(time){if(typeof time!=="number")time=Date.now()/1e3;time=parseInt(time,10)%4294967295;return hex(8,time)+hex(6,MACHINE_ID)+hex(4,pid)+hex(6,next())}__name(generate,"generate");function hex(length,n){n=n.toString(16);return n.length===length?n:"00000000".substring(n.length,length)+n}__name(hex,"hex");function buffer(str){var i=0,out=[];if(str.length===24)for(;i<24;out.push(parseInt(str[i]+str[i+1],16)),i+=2);else if(str.length===12)for(;i<12;out.push(str.charCodeAt(i)),i++);return out}__name(buffer,"buffer");var inspect=Symbol&&Symbol.for("nodejs.util.inspect.custom")||"inspect";ObjectID.prototype[inspect]=function(){return"ObjectID("+this+")"};ObjectID.prototype.toJSON=ObjectID.prototype.toHexString;ObjectID.prototype.toString=ObjectID.prototype.toHexString;const bsonObjectId=getDefaultExportFromCjs(objectid);function cutSequenceByRestrictionEnzyme(pSequence,circular,restrictionEnzyme){if(restrictionEnzyme.forwardRegex.length===0||restrictionEnzyme.reverseRegex.length===0){let returnArray=[];returnArray.error="Cannot cut sequence. Enzyme restriction site must be at least 1 bp long.";return returnArray}let forwardRegExpPattern=new RegExp(restrictionEnzyme.forwardRegex,"ig");let sequence=pSequence;let cutsitesForward=cutSequence(forwardRegExpPattern,restrictionEnzyme,sequence,circular);let cutsitesReverse=[];if(restrictionEnzyme.forwardRegex!==restrictionEnzyme.reverseRegex){let revSequence=getReverseComplementSequenceString(sequence);cutsitesReverse=cutSequence(forwardRegExpPattern,restrictionEnzyme,revSequence,circular);cutsitesReverse=cutsitesReverse.map(cutsite=>{return reverseAllPositionsOfCutsite(cutsite,sequence.length)})}return cutsitesForward.concat(cutsitesReverse);function reverseAllPositionsOfCutsite(cutsite,rangeLength){cutsite.start=reversePositionInRange(cutsite.start,rangeLength,false);cutsite.end=reversePositionInRange(cutsite.end,rangeLength,false);cutsite.topSnipPosition=reversePositionInRange(cutsite.topSnipPosition,rangeLength,true);cutsite.bottomSnipPosition=reversePositionInRange(cutsite.bottomSnipPosition,rangeLength,true);if(cutsite.cutsTwice){cutsite.upstreamTopSnip=reversePositionInRange(cutsite.upstreamTopSnip,rangeLength,true);cutsite.upstreamBottomSnip=reversePositionInRange(cutsite.upstreamBottomSnip,rangeLength,true)}cutsite.recognitionSiteRange.start=reversePositionInRange(cutsite.recognitionSiteRange.start,rangeLength,false);cutsite.recognitionSiteRange.end=reversePositionInRange(cutsite.recognitionSiteRange.end,rangeLength,false);return lodashExports.assign({},cutsite,{start:cutsite.end,end:cutsite.start,overhangBps:getReverseComplementSequenceString(cutsite.overhangBps),topSnipPosition:cutsite.bottomSnipPosition,bottomSnipPosition:cutsite.topSnipPosition,upstreamTopSnip:cutsite.upstreamBottomSnip,upstreamBottomSnip:cutsite.upstreamTopSnip,upstreamTopBeforeBottom:!!cutsite.upstreamTopBeforeBottom,topSnipBeforeBottom:!!cutsite.topSnipBeforeBottom,recognitionSiteRange:{start:cutsite.recognitionSiteRange.end,end:cutsite.recognitionSiteRange.start},forward:false})}__name(reverseAllPositionsOfCutsite,"reverseAllPositionsOfCutsite")}__name(cutSequenceByRestrictionEnzyme,"cutSequenceByRestrictionEnzyme");function cutSequence(forwardRegExpPattern,restrictionEnzyme,sequence,circular){let restrictionCutSites=[];let restrictionCutSite;let recognitionSiteLength=restrictionEnzyme.site.length;let originalSequence=sequence;let originalSequenceLength=sequence.length;if(circular){sequence+=sequence}let currentSequenceLength=sequence.length;let matchIndex=sequence.search(forwardRegExpPattern);let startIndex=0;let subSequence=sequence;while(matchIndex!==-1){let recognitionSiteRange={};let start;let end;let upstreamTopSnip=null;let upstreamBottomSnip=null;let upstreamTopBeforeBottom=false;let topSnipPosition=null;let bottomSnipPosition=null;let topSnipBeforeBottom=false;let fitsWithinSequence=false;recognitionSiteRange.start=matchIndex+startIndex;start=recognitionSiteRange.start;recognitionSiteRange.end=matchIndex+recognitionSiteLength-1+startIndex;end=recognitionSiteRange.end;if(restrictionEnzyme.cutType===1){upstreamTopSnip=recognitionSiteRange.end-restrictionEnzyme.usForward;upstreamBottomSnip=recognitionSiteRange.end-restrictionEnzyme.usReverse;if(upstreamTopSnip>=0&&upstreamBottomSnip>=0){fitsWithinSequence=true;if(upstreamTopSnip<upstreamBottomSnip){if(start>upstreamTopSnip){start=upstreamTopSnip+1}upstreamTopBeforeBottom=true}else{if(start>upstreamBottomSnip){start=upstreamBottomSnip+1}}upstreamTopSnip=normalizePositionByRangeLength(upstreamTopSnip,originalSequenceLength,true);upstreamBottomSnip=normalizePositionByRangeLength(upstreamBottomSnip,originalSequenceLength,true)}else{upstreamTopSnip=null;upstreamBottomSnip=null}}topSnipPosition=recognitionSiteRange.start+restrictionEnzyme.topSnipOffset;bottomSnipPosition=recognitionSiteRange.start+restrictionEnzyme.bottomSnipOffset;if(bottomSnipPosition<=currentSequenceLength&&topSnipPosition<=currentSequenceLength){fitsWithinSequence=true;if(topSnipPosition>bottomSnipPosition){if(topSnipPosition>recognitionSiteRange.end){end=topSnipPosition-1}}else{if(bottomSnipPosition>recognitionSiteRange.end){end=bottomSnipPosition-1}topSnipBeforeBottom=true}topSnipPosition=normalizePositionByRangeLength(topSnipPosition,originalSequenceLength,true);bottomSnipPosition=normalizePositionByRangeLength(bottomSnipPosition,originalSequenceLength,true)}else{topSnipPosition=null;bottomSnipPosition=null}if(fitsWithinSequence&&start>=0&&end>=0&&start<originalSequenceLength&&end<currentSequenceLength){start=normalizePositionByRangeLength(start,originalSequenceLength,false);end=normalizePositionByRangeLength(end,originalSequenceLength,false);recognitionSiteRange.start=normalizePositionByRangeLength(recognitionSiteRange.start,originalSequenceLength,false);recognitionSiteRange.end=normalizePositionByRangeLength(recognitionSiteRange.end,originalSequenceLength,false);let cutRange={start:-1,end:-1};if(topSnipPosition!==bottomSnipPosition){cutRange=topSnipBeforeBottom?{start:topSnipPosition,end:normalizePositionByRangeLength(bottomSnipPosition-1,originalSequenceLength)}:{start:bottomSnipPosition,end:normalizePositionByRangeLength(topSnipPosition-1,originalSequenceLength)}}let overhangBps=getSequenceWithinRange(cutRange,originalSequence);restrictionCutSite={id:bsonObjectId().str,start,end,topSnipPosition,bottomSnipPosition,topSnipBeforeBottom,overhangBps,overhangSize:overhangBps.length,upstreamTopBeforeBottom,upstreamTopSnip,annotationTypePlural:"cutsites",upstreamBottomSnip,recognitionSiteRange,forward:true,name:restrictionEnzyme.name,restrictionEnzyme};restrictionCutSites.push(restrictionCutSite)}startIndex=startIndex+matchIndex+1;subSequence=sequence.substring(startIndex,sequence.length);matchIndex=subSequence.search(forwardRegExpPattern)}return restrictionCutSites}__name(cutSequence,"cutSequence");function getCutsitesFromSequence(sequence,circular,restrictionEnzymes){const cutsitesByName={};for(let i=0;i<restrictionEnzymes.length;i++){const re=restrictionEnzymes[i];const cutsites=cutSequenceByRestrictionEnzyme(sequence,circular,re);if(cutsites.length){cutsitesByName[re.name]=cutsites}}return cutsitesByName}__name(getCutsitesFromSequence,"getCutsitesFromSequence");function computeDigestFragments({cutsites,sequenceLength,circular,includeOverAndUnderHangs,computePartialDigest,computeDigestDisabled,computePartialDigestDisabled,selectionLayerUpdate,updateSelectedFragment}){const fragments=[];const overlappingEnzymes=[];const pairs=[];const sortedCutsites=cutsites.sort((a,b)=>{return a.topSnipPosition-b.topSnipPosition});if(!circular&&cutsites.length){sortedCutsites.push({id:"seqTerm_"+bsonObjectId().str,start:0,end:0,overhangBps:"",topSnipPosition:0,bottomSnipPosition:0,upstreamTopSnip:0,upstreamBottomSnip:0,upstreamTopBeforeBottom:false,topSnipBeforeBottom:false,recognitionSiteRange:{start:0,end:0},forward:true,name:"Sequence_Terminus",restrictionEnzyme:{name:"Sequence_Terminus"}})}sortedCutsites.forEach((cutsite1,index2)=>{if(computePartialDigest&&!computePartialDigestDisabled){sortedCutsites.forEach((cs,index22)=>{if(index22===index2+1||index22===0){return}pairs.push([cutsite1,sortedCutsites[index22]])})}if(!computeDigestDisabled){pairs.push([cutsite1,sortedCutsites[index2+1]?sortedCutsites[index2+1]:sortedCutsites[0]])}});pairs.forEach(r=>{let[cut1,cut2]=r;let start;let end;let size;start=normalizePositionByRangeLength(cut1.topSnipPosition,sequenceLength);end=normalizePositionByRangeLength(cut2.topSnipPosition-1,sequenceLength);size=getRangeLength({start,end},sequenceLength);let overlapsSelf;if(includeOverAndUnderHangs){const oldSize=size;start=normalizePositionByRangeLength(cut1.topSnipBeforeBottom?cut1.topSnipPosition:cut1.bottomSnipPosition,sequenceLength);end=normalizePositionByRangeLength(cut2.topSnipBeforeBottom?cut2.bottomSnipPosition-1:cut2.topSnipPosition-1,sequenceLength);size=getRangeLength({start,end},sequenceLength);if(oldSize>size){overlapsSelf=true;size+=sequenceLength}}let isFormedFromLinearEnd;if(cut1.name==="Sequence_Terminus"){cut1=lodashExports.cloneDeep(cut1);isFormedFromLinearEnd=true;cut1.name="Linear_Sequence_Start";cut1.restrictionEnzyme.name="Linear_Sequence_Start"}else if(cut2.name==="Sequence_Terminus"){cut2=lodashExports.cloneDeep(cut2);isFormedFromLinearEnd=true;cut2.name="Linear_Sequence_End";cut2.restrictionEnzyme.name="Linear_Sequence_End"}const id=start+"-"+end+"-"+size+"-";const name=`${cut1.restrictionEnzyme.name} -- ${cut2.restrictionEnzyme.name} ${size} bps`;getRangeLength({start,end},sequenceLength);fragments.push({isFormedFromLinearEnd,madeFromOneCutsite:cut1===cut2,start,end,size,overlapsSelf,id,name,cut1,cut2,onFragmentSelect:selectionLayerUpdate&&updateSelectedFragment?()=>{selectionLayerUpdate({start,end,name});updateSelectedFragment(id)}:void 0})});fragments.filter(fragment=>{if(!fragment.size){overlappingEnzymes.push(fragment);return false}return true});return{computePartialDigestDisabled,computeDigestDisabled,fragments,overlappingEnzymes}}__name(computeDigestFragments,"computeDigestFragments");function getDigestFragsForSeqAndEnzymes({sequence,circular,enzymes,includeOverAndUnderHangs}){const cutsitesByName=getCutsitesFromSequence(sequence,circular,enzymes);return computeDigestFragments({includeOverAndUnderHangs,cutsites:lodashExports.flatMap(cutsitesByName),sequenceLength:sequence.length,circular})}__name(getDigestFragsForSeqAndEnzymes,"getDigestFragsForSeqAndEnzymes");var diffMatchPatch={exports:{}};(function(module2){var diff_match_patch2=__name(function(){this.Diff_Timeout=1;this.Diff_EditCost=4;this.Match_Threshold=.5;this.Match_Distance=1e3;this.Patch_DeleteThreshold=.5;this.Patch_Margin=4;this.Match_MaxBits=32},"diff_match_patch");var DIFF_DELETE=-1;var DIFF_INSERT=1;var DIFF_EQUAL=0;diff_match_patch2.Diff=function(op,text){return[op,text]};diff_match_patch2.prototype.diff_main=function(text1,text2,opt_checklines,opt_deadline){if(typeof opt_deadline=="undefined"){if(this.Diff_Timeout<=0){opt_deadline=Number.MAX_VALUE}else{opt_deadline=new Date().getTime()+this.Diff_Timeout*1e3}}var deadline=opt_deadline;if(text1==null||text2==null){throw new Error("Null input. (diff_main)")}if(text1==text2){if(text1){return[new diff_match_patch2.Diff(DIFF_EQUAL,text1)]}return[]}if(typeof opt_checklines=="undefined"){opt_checklines=true}var checklines=opt_checklines;var commonlength=this.diff_commonPrefix(text1,text2);var commonprefix=text1.substring(0,commonlength);text1=text1.substring(commonlength);text2=text2.substring(commonlength);commonlength=this.diff_commonSuffix(text1,text2);var commonsuffix=text1.substring(text1.length-commonlength);text1=text1.substring(0,text1.length-commonlength);text2=text2.substring(0,text2.length-commonlength);var diffs=this.diff_compute_(text1,text2,checklines,deadline);if(commonprefix){diffs.unshift(new diff_match_patch2.Diff(DIFF_EQUAL,commonprefix))}if(commonsuffix){diffs.push(new diff_match_patch2.Diff(DIFF_EQUAL,commonsuffix))}this.diff_cleanupMerge(diffs);return diffs};diff_match_patch2.prototype.diff_compute_=function(text1,text2,checklines,deadline){var diffs;if(!text1){return[new diff_match_patch2.Diff(DIFF_INSERT,text2)]}if(!text2){return[new diff_match_patch2.Diff(DIFF_DELETE,text1)]}var longtext=text1.length>text2.length?text1:text2;var shorttext=text1.length>text2.length?text2:text1;var i=longtext.indexOf(shorttext);if(i!=-1){diffs=[new diff_match_patch2.Diff(DIFF_INSERT,longtext.substring(0,i)),new diff_match_patch2.Diff(DIFF_EQUAL,shorttext),new diff_match_patch2.Diff(DIFF_INSERT,longtext.substring(i+shorttext.length))];if(text1.length>text2.length){diffs[0][0]=diffs[2][0]=DIFF_DELETE}return diffs}if(shorttext.length==1){return[new diff_match_patch2.Diff(DIFF_DELETE,text1),new diff_match_patch2.Diff(DIFF_INSERT,text2)]}var hm=this.diff_halfMatch_(text1,text2);if(hm){var text1_a=hm[0];var text1_b=hm[1];var text2_a=hm[2];var text2_b=hm[3];var mid_common=hm[4];var diffs_a=this.diff_main(text1_a,text2_a,checklines,deadline);var diffs_b=this.diff_main(text1_b,text2_b,checklines,deadline);return diffs_a.concat([new diff_match_patch2.Diff(DIFF_EQUAL,mid_common)],diffs_b)}if(checklines&&text1.length>100&&text2.length>100){return this.diff_lineMode_(text1,text2,deadline)}return this.diff_bisect_(text1,text2,deadline)};diff_match_patch2.prototype.diff_lineMode_=function(text1,text2,deadline){var a=this.diff_linesToChars_(text1,text2);text1=a.chars1;text2=a.chars2;var linearray=a.lineArray;var diffs=this.diff_main(text1,text2,false,deadline);this.diff_charsToLines_(diffs,linearray);this.diff_cleanupSemantic(diffs);diffs.push(new diff_match_patch2.Diff(DIFF_EQUAL,""));var pointer=0;var count_delete=0;var count_insert=0;var text_delete="";var text_insert="";while(pointer<diffs.length){switch(diffs[pointer][0]){case DIFF_INSERT:count_insert++;text_insert+=diffs[pointer][1];break;case DIFF_DELETE:count_delete++;text_delete+=diffs[pointer][1];break;case DIFF_EQUAL:if(count_delete>=1&&count_insert>=1){diffs.splice(pointer-count_delete-count_insert,count_delete+count_insert);pointer=pointer-count_delete-count_insert;var subDiff=this.diff_main(text_delete,text_insert,false,deadline);for(var j=subDiff.length-1;j>=0;j--){diffs.splice(pointer,0,subDiff[j])}pointer=pointer+subDiff.length}count_insert=0;count_delete=0;text_delete="";text_insert="";break}pointer++}diffs.pop();return diffs};diff_match_patch2.prototype.diff_bisect_=function(text1,text2,deadline){var text1_length=text1.length;var text2_length=text2.length;var max_d=Math.ceil((text1_length+text2_length)/2);var v_offset=max_d;var v_length=2*max_d;var v1=new Array(v_length);var v2=new Array(v_length);for(var x=0;x<v_length;x++){v1[x]=-1;v2[x]=-1}v1[v_offset+1]=0;v2[v_offset+1]=0;var delta=text1_length-text2_length;var front=delta%2!=0;var k1start=0;var k1end=0;var k2start=0;var k2end=0;for(var d=0;d<max_d;d++){if(new Date().getTime()>deadline){break}for(var k1=-d+k1start;k1<=d-k1end;k1+=2){var k1_offset=v_offset+k1;var x1;if(k1==-d||k1!=d&&v1[k1_offset-1]<v1[k1_offset+1]){x1=v1[k1_offset+1]}else{x1=v1[k1_offset-1]+1}var y1=x1-k1;while(x1<text1_length&&y1<text2_length&&text1.charAt(x1)==text2.charAt(y1)){x1++;y1++}v1[k1_offset]=x1;if(x1>text1_length){k1end+=2}else if(y1>text2_length){k1start+=2}else if(front){var k2_offset=v_offset+delta-k1;if(k2_offset>=0&&k2_offset<v_length&&v2[k2_offset]!=-1){var x2=text1_length-v2[k2_offset];if(x1>=x2){return this.diff_bisectSplit_(text1,text2,x1,y1,deadline)}}}}for(var k2=-d+k2start;k2<=d-k2end;k2+=2){var k2_offset=v_offset+k2;var x2;if(k2==-d||k2!=d&&v2[k2_offset-1]<v2[k2_offset+1]){x2=v2[k2_offset+1]}else{x2=v2[k2_offset-1]+1}var y2=x2-k2;while(x2<text1_length&&y2<text2_length&&text1.charAt(text1_length-x2-1)==text2.charAt(text2_length-y2-1)){x2++;y2++}v2[k2_offset]=x2;if(x2>text1_length){k2end+=2}else if(y2>text2_length){k2start+=2}else if(!front){var k1_offset=v_offset+delta-k2;if(k1_offset>=0&&k1_offset<v_length&&v1[k1_offset]!=-1){var x1=v1[k1_offset];var y1=v_offset+x1-k1_offset;x2=text1_length-x2;if(x1>=x2){return this.diff_bisectSplit_(text1,text2,x1,y1,deadline)}}}}}return[new diff_match_patch2.Diff(DIFF_DELETE,text1),new diff_match_patch2.Diff(DIFF_INSERT,text2)]};diff_match_patch2.prototype.diff_bisectSplit_=function(text1,text2,x,y,deadline){var text1a=text1.substring(0,x);var text2a=text2.substring(0,y);var text1b=text1.substring(x);var text2b=text2.substring(y);var diffs=this.diff_main(text1a,text2a,false,deadline);var diffsb=this.diff_main(text1b,text2b,false,deadline);return diffs.concat(diffsb)};diff_match_patch2.prototype.diff_linesToChars_=function(text1,text2){var lineArray=[];var lineHash={};lineArray[0]="";function diff_linesToCharsMunge_(text){var chars="";var lineStart=0;var lineEnd=-1;var lineArrayLength=lineArray.length;while(lineEnd<text.length-1){lineEnd=text.indexOf("\n",lineStart);if(lineEnd==-1){lineEnd=text.length-1}var line=text.substring(lineStart,lineEnd+1);if(lineHash.hasOwnProperty?lineHash.hasOwnProperty(line):lineHash[line]!==void 0){chars+=String.fromCharCode(lineHash[line])}else{if(lineArrayLength==maxLines){line=text.substring(lineStart);lineEnd=text.length}chars+=String.fromCharCode(lineArrayLength);lineHash[line]=lineArrayLength;lineArray[lineArrayLength++]=line}lineStart=lineEnd+1}return chars}__name(diff_linesToCharsMunge_,"diff_linesToCharsMunge_");var maxLines=4e4;var chars1=diff_linesToCharsMunge_(text1);maxLines=65535;var chars2=diff_linesToCharsMunge_(text2);return{chars1,chars2,lineArray}};diff_match_patch2.prototype.diff_charsToLines_=function(diffs,lineArray){for(var i=0;i<diffs.length;i++){var chars=diffs[i][1];var text=[];for(var j=0;j<chars.length;j++){text[j]=lineArray[chars.charCodeAt(j)]}diffs[i][1]=text.join("")}};diff_match_patch2.prototype.diff_commonPrefix=function(text1,text2){if(!text1||!text2||text1.charAt(0)!=text2.charAt(0)){return 0}var pointermin=0;var pointermax=Math.min(text1.length,text2.length);var pointermid=pointermax;var pointerstart=0;while(pointermin<pointermid){if(text1.substring(pointerstart,pointermid)==text2.substring(pointerstart,pointermid)){pointermin=pointermid;pointerstart=pointermin}else{pointermax=pointermid}pointermid=Math.floor((pointermax-pointermin)/2+pointermin)}return pointermid};diff_match_patch2.prototype.diff_commonSuffix=function(text1,text2){if(!text1||!text2||text1.charAt(text1.length-1)!=text2.charAt(text2.length-1)){return 0}var pointermin=0;var pointermax=Math.min(text1.length,text2.length);var pointermid=pointermax;var pointerend=0;while(pointermin<pointermid){if(text1.substring(text1.length-pointermid,text1.length-pointerend)==text2.substring(text2.length-pointermid,text2.length-pointerend)){pointermin=pointermid;pointerend=pointermin}else{pointermax=pointermid}pointermid=Math.floor((pointermax-pointermin)/2+pointermin)}return pointermid};diff_match_patch2.prototype.diff_commonOverlap_=function(text1,text2){var text1_length=text1.length;var text2_length=text2.length;if(text1_length==0||text2_length==0){return 0}if(text1_length>text2_length){text1=text1.substring(text1_length-text2_length)}else if(text1_length<text2_length){text2=text2.substring(0,text1_length)}var text_length=Math.min(text1_length,text2_length);if(text1==text2){return text_length}var best=0;var length=1;while(true){var pattern=text1.substring(text_length-length);var found=text2.indexOf(pattern);if(found==-1){return best}length+=found;if(found==0||text1.substring(text_length-length)==text2.substring(0,length)){best=length;length++}}};diff_match_patch2.prototype.diff_halfMatch_=function(text1,text2){if(this.Diff_Timeout<=0){return null}var longtext=text1.length>text2.length?text1:text2;var shorttext=text1.length>text2.length?text2:text1;if(longtext.length<4||shorttext.length*2<longtext.length){return null}var dmp2=this;function diff_halfMatchI_(longtext2,shorttext2,i){var seed=longtext2.substring(i,i+Math.floor(longtext2.length/4));var j=-1;var best_common="";var best_longtext_a,best_longtext_b,best_shorttext_a,best_shorttext_b;while((j=shorttext2.indexOf(seed,j+1))!=-1){var prefixLength=dmp2.diff_commonPrefix(longtext2.substring(i),shorttext2.substring(j));var suffixLength=dmp2.diff_commonSuffix(longtext2.substring(0,i),shorttext2.substring(0,j));if(best_common.length<suffixLength+prefixLength){best_common=shorttext2.substring(j-suffixLength,j)+shorttext2.substring(j,j+prefixLength);best_longtext_a=longtext2.substring(0,i-suffixLength);best_longtext_b=longtext2.substring(i+prefixLength);best_shorttext_a=shorttext2.substring(0,j-suffixLength);best_shorttext_b=shorttext2.substring(j+prefixLength)}}if(best_common.length*2>=longtext2.length){return[best_longtext_a,best_longtext_b,best_shorttext_a,best_shorttext_b,best_common]}else{return null}}__name(diff_halfMatchI_,"diff_halfMatchI_");var hm1=diff_halfMatchI_(longtext,shorttext,Math.ceil(longtext.length/4));var hm2=diff_halfMatchI_(longtext,shorttext,Math.ceil(longtext.length/2));var hm;if(!hm1&&!hm2){return null}else if(!hm2){hm=hm1}else if(!hm1){hm=hm2}else{hm=hm1[4].length>hm2[4].length?hm1:hm2}var text1_a,text1_b,text2_a,text2_b;if(text1.length>text2.length){text1_a=hm[0];text1_b=hm[1];text2_a=hm[2];text2_b=hm[3]}else{text2_a=hm[0];text2_b=hm[1];text1_a=hm[2];text1_b=hm[3]}var mid_common=hm[4];return[text1_a,text1_b,text2_a,text2_b,mid_common]};diff_match_patch2.prototype.diff_cleanupSemantic=function(diffs){var changes=false;var equalities=[];var equalitiesLength=0;var lastEquality=null;var pointer=0;var length_insertions1=0;var length_deletions1=0;var length_insertions2=0;var length_deletions2=0;while(pointer<diffs.length){if(diffs[pointer][0]==DIFF_EQUAL){equalities[equalitiesLength++]=pointer;length_insertions1=length_insertions2;length_deletions1=length_deletions2;length_insertions2=0;length_deletions2=0;lastEquality=diffs[pointer][1]}else{if(diffs[pointer][0]==DIFF_INSERT){length_insertions2+=diffs[pointer][1].length}else{length_deletions2+=diffs[pointer][1].length}if(lastEquality&&lastEquality.length<=Math.max(length_insertions1,length_deletions1)&&lastEquality.length<=Math.max(length_insertions2,length_deletions2)){diffs.splice(equalities[equalitiesLength-1],0,new diff_match_patch2.Diff(DIFF_DELETE,lastEquality));diffs[equalities[equalitiesLength-1]+1][0]=DIFF_INSERT;equalitiesLength--;equalitiesLength--;pointer=equalitiesLength>0?equalities[equalitiesLength-1]:-1;length_insertions1=0;length_deletions1=0;length_insertions2=0;length_deletions2=0;lastEquality=null;changes=true}}pointer++}if(changes){this.diff_cleanupMerge(diffs)}this.diff_cleanupSemanticLossless(diffs);pointer=1;while(pointer<diffs.length){if(diffs[pointer-1][0]==DIFF_DELETE&&diffs[pointer][0]==DIFF_INSERT){var deletion=diffs[pointer-1][1];var insertion=diffs[pointer][1];var overlap_length1=this.diff_commonOverlap_(deletion,insertion);var overlap_length2=this.diff_commonOverlap_(insertion,deletion);if(overlap_length1>=overlap_length2){if(overlap_length1>=deletion.length/2||overlap_length1>=insertion.length/2){diffs.splice(pointer,0,new diff_match_patch2.Diff(DIFF_EQUAL,insertion.substring(0,overlap_length1)));diffs[pointer-1][1]=deletion.substring(0,deletion.length-overlap_length1);diffs[pointer+1][1]=insertion.substring(overlap_length1);pointer++}}else{if(overlap_length2>=deletion.length/2||overlap_length2>=insertion.length/2){diffs.splice(pointer,0,new diff_match_patch2.Diff(DIFF_EQUAL,deletion.substring(0,overlap_length2)));diffs[pointer-1][0]=DIFF_INSERT;diffs[pointer-1][1]=insertion.substring(0,insertion.length-overlap_length2);diffs[pointer+1][0]=DIFF_DELETE;diffs[pointer+1][1]=deletion.substring(overlap_length2);pointer++}}pointer++}pointer++}};diff_match_patch2.prototype.diff_cleanupSemanticLossless=function(diffs){function diff_cleanupSemanticScore_(one,two){if(!one||!two){return 6}var char1=one.charAt(one.length-1);var char2=two.charAt(0);var nonAlphaNumeric1=char1.match(diff_match_patch2.nonAlphaNumericRegex_);var nonAlphaNumeric2=char2.match(diff_match_patch2.nonAlphaNumericRegex_);var whitespace1=nonAlphaNumeric1&&char1.match(diff_match_patch2.whitespaceRegex_);var whitespace2=nonAlphaNumeric2&&char2.match(diff_match_patch2.whitespaceRegex_);var lineBreak1=whitespace1&&char1.match(diff_match_patch2.linebreakRegex_);var lineBreak2=whitespace2&&char2.match(diff_match_patch2.linebreakRegex_);var blankLine1=lineBreak1&&one.match(diff_match_patch2.blanklineEndRegex_);var blankLine2=lineBreak2&&two.match(diff_match_patch2.blanklineStartRegex_);if(blankLine1||blankLine2){return 5}else if(lineBreak1||lineBreak2){return 4}else if(nonAlphaNumeric1&&!whitespace1&&whitespace2){return 3}else if(whitespace1||whitespace2){return 2}else if(nonAlphaNumeric1||nonAlphaNumeric2){return 1}return 0}__name(diff_cleanupSemanticScore_,"diff_cleanupSemanticScore_");var pointer=1;while(pointer<diffs.length-1){if(diffs[pointer-1][0]==DIFF_EQUAL&&diffs[pointer+1][0]==DIFF_EQUAL){var equality1=diffs[pointer-1][1];var edit=diffs[pointer][1];var equality2=diffs[pointer+1][1];var commonOffset=this.diff_commonSuffix(equality1,edit);if(commonOffset){var commonString=edit.substring(edit.length-commonOffset);equality1=equality1.substring(0,equality1.length-commonOffset);edit=commonString+edit.substring(0,edit.length-commonOffset);equality2=commonString+equality2}var bestEquality1=equality1;var bestEdit=edit;var bestEquality2=equality2;var bestScore=diff_cleanupSemanticScore_(equality1,edit)+diff_cleanupSemanticScore_(edit,equality2);while(edit.charAt(0)===equality2.charAt(0)){equality1+=edit.charAt(0);edit=edit.substring(1)+equality2.charAt(0);equality2=equality2.substring(1);var score=diff_cleanupSemanticScore_(equality1,edit)+diff_cleanupSemanticScore_(edit,equality2);if(score>=bestScore){bestScore=score;bestEquality1=equality1;bestEdit=edit;bestEquality2=equality2}}if(diffs[pointer-1][1]!=bestEquality1){if(bestEquality1){diffs[pointer-1][1]=bestEquality1}else{diffs.splice(pointer-1,1);pointer--}diffs[pointer][1]=bestEdit;if(bestEquality2){diffs[pointer+1][1]=bestEquality2}else{diffs.splice(pointer+1,1);pointer--}}}pointer++}};diff_match_patch2.nonAlphaNumericRegex_=/[^a-zA-Z0-9]/;diff_match_patch2.whitespaceRegex_=/\s/;diff_match_patch2.linebreakRegex_=/[\r\n]/;diff_match_patch2.blanklineEndRegex_=/\n\r?\n$/;diff_match_patch2.blanklineStartRegex_=/^\r?\n\r?\n/;diff_match_patch2.prototype.diff_cleanupEfficiency=function(diffs){var changes=false;var equalities=[];var equalitiesLength=0;var lastEquality=null;var pointer=0;var pre_ins=false;var pre_del=false;var post_ins=false;var post_del=false;while(pointer<diffs.length){if(diffs[pointer][0]==DIFF_EQUAL){if(diffs[pointer][1].length<this.Diff_EditCost&&(post_ins||post_del)){equalities[equalitiesLength++]=pointer;pre_ins=post_ins;pre_del=post_del;lastEquality=diffs[pointer][1]}else{equalitiesLength=0;lastEquality=null}post_ins=post_del=false}else{if(diffs[pointer][0]==DIFF_DELETE){post_del=true}else{post_ins=true}if(lastEquality&&(pre_ins&&pre_del&&post_ins&&post_del||lastEquality.length<this.Diff_EditCost/2&&pre_ins+pre_del+post_ins+post_del==3)){diffs.splice(equalities[equalitiesLength-1],0,new diff_match_patch2.Diff(DIFF_DELETE,lastEquality));diffs[equalities[equalitiesLength-1]+1][0]=DIFF_INSERT;equalitiesLength--;lastEquality=null;if(pre_ins&&pre_del){post_ins=post_del=true;equalitiesLength=0}else{equalitiesLength--;pointer=equalitiesLength>0?equalities[equalitiesLength-1]:-1;post_ins=post_del=false}changes=true}}pointer++}if(changes){this.diff_cleanupMerge(diffs)}};diff_match_patch2.prototype.diff_cleanupMerge=function(diffs){diffs.push(new diff_match_patch2.Diff(DIFF_EQUAL,""));var pointer=0;var count_delete=0;var count_insert=0;var text_delete="";var text_insert="";var commonlength;while(pointer<diffs.length){switch(diffs[pointer][0]){case DIFF_INSERT:count_insert++;text_insert+=diffs[pointer][1];pointer++;break;case DIFF_DELETE:count_delete++;text_delete+=diffs[pointer][1];pointer++;break;case DIFF_EQUAL:if(count_delete+count_insert>1){if(count_delete!==0&&count_insert!==0){commonlength=this.diff_commonPrefix(text_insert,text_delete);if(commonlength!==0){if(pointer-count_delete-count_insert>0&&diffs[pointer-count_delete-count_insert-1][0]==DIFF_EQUAL){diffs[pointer-count_delete-count_insert-1][1]+=text_insert.substring(0,commonlength)}else{diffs.splice(0,0,new diff_match_patch2.Diff(DIFF_EQUAL,text_insert.substring(0,commonlength)));pointer++}text_insert=text_insert.substring(commonlength);text_delete=text_delete.substring(commonlength)}commonlength=this.diff_commonSuffix(text_insert,text_delete);if(commonlength!==0){diffs[pointer][1]=text_insert.substring(text_insert.length-commonlength)+diffs[pointer][1];text_insert=text_insert.substring(0,text_insert.length-commonlength);text_delete=text_delete.substring(0,text_delete.length-commonlength)}}pointer-=count_delete+count_insert;diffs.splice(pointer,count_delete+count_insert);if(text_delete.length){diffs.splice(pointer,0,new diff_match_patch2.Diff(DIFF_DELETE,text_delete));pointer++}if(text_insert.length){diffs.splice(pointer,0,new diff_match_patch2.Diff(DIFF_INSERT,text_insert));pointer++}pointer++}else if(pointer!==0&&diffs[pointer-1][0]==DIFF_EQUAL){diffs[pointer-1][1]+=diffs[pointer][1];diffs.splice(pointer,1)}else{pointer++}count_insert=0;count_delete=0;text_delete="";text_insert="";break}}if(diffs[diffs.length-1][1]===""){diffs.pop()}var changes=false;pointer=1;while(pointer<diffs.length-1){if(diffs[pointer-1][0]==DIFF_EQUAL&&diffs[pointer+1][0]==DIFF_EQUAL){if(diffs[pointer][1].substring(diffs[pointer][1].length-diffs[pointer-1][1].length)==diffs[pointer-1][1]){diffs[pointer][1]=diffs[pointer-1][1]+diffs[pointer][1].substring(0,diffs[pointer][1].length-diffs[pointer-1][1].length);diffs[pointer+1][1]=diffs[pointer-1][1]+diffs[pointer+1][1];diffs.splice(pointer-1,1);changes=true}else if(diffs[pointer][1].substring(0,diffs[pointer+1][1].length)==diffs[pointer+1][1]){diffs[pointer-1][1]+=diffs[pointer+1][1];diffs[pointer][1]=diffs[pointer][1].substring(diffs[pointer+1][1].length)+diffs[pointer+1][1];diffs.splice(pointer+1,1);changes=true}}pointer++}if(changes){this.diff_cleanupMerge(diffs)}};diff_match_patch2.prototype.diff_xIndex=function(diffs,loc){var chars1=0;var chars2=0;var last_chars1=0;var last_chars2=0;var x;for(x=0;x<diffs.length;x++){if(diffs[x][0]!==DIFF_INSERT){chars1+=diffs[x][1].length}if(diffs[x][0]!==DIFF_DELETE){chars2+=diffs[x][1].length}if(chars1>loc){break}last_chars1=chars1;last_chars2=chars2}if(diffs.length!=x&&diffs[x][0]===DIFF_DELETE){return last_chars2}return last_chars2+(loc-last_chars1)};diff_match_patch2.prototype.diff_prettyHtml=function(diffs){var html=[];var pattern_amp=/&/g;var pattern_lt=/</g;var pattern_gt=/>/g;var pattern_para=/\n/g;for(var x=0;x<diffs.length;x++){var op=diffs[x][0];var data=diffs[x][1];var text=data.replace(pattern_amp,"&amp;").replace(pattern_lt,"&lt;").replace(pattern_gt,"&gt;").replace(pattern_para,"&para;<br>");switch(op){case DIFF_INSERT:html[x]='<ins style="background:#e6ffe6;">'+text+"</ins>";break;case DIFF_DELETE:html[x]='<del style="background:#ffe6e6;">'+text+"</del>";break;case DIFF_EQUAL:html[x]="<span>"+text+"</span>";break}}return html.join("")};diff_match_patch2.prototype.diff_text1=function(diffs){var text=[];for(var x=0;x<diffs.length;x++){if(diffs[x][0]!==DIFF_INSERT){text[x]=diffs[x][1]}}return text.join("")};diff_match_patch2.prototype.diff_text2=function(diffs){var text=[];for(var x=0;x<diffs.length;x++){if(diffs[x][0]!==DIFF_DELETE){text[x]=diffs[x][1]}}return text.join("")};diff_match_patch2.prototype.diff_levenshtein=function(diffs){var levenshtein=0;var insertions=0;var deletions=0;for(var x=0;x<diffs.length;x++){var op=diffs[x][0];var data=diffs[x][1];switch(op){case DIFF_INSERT:insertions+=data.length;break;case DIFF_DELETE:deletions+=data.length;break;case DIFF_EQUAL:levenshtein+=Math.max(insertions,deletions);insertions=0;deletions=0;break}}levenshtein+=Math.max(insertions,deletions);return levenshtein};diff_match_patch2.prototype.diff_toDelta=function(diffs){var text=[];for(var x=0;x<diffs.length;x++){switch(diffs[x][0]){case DIFF_INSERT:text[x]="+"+encodeURI(diffs[x][1]);break;case DIFF_DELETE:text[x]="-"+diffs[x][1].length;break;case DIFF_EQUAL:text[x]="="+diffs[x][1].length;break}}return text.join("	").replace(/%20/g," ")};diff_match_patch2.prototype.diff_fromDelta=function(text1,delta){var diffs=[];var diffsLength=0;var pointer=0;var tokens=delta.split(/\t/g);for(var x=0;x<tokens.length;x++){var param=tokens[x].substring(1);switch(tokens[x].charAt(0)){case"+":try{diffs[diffsLength++]=new diff_match_patch2.Diff(DIFF_INSERT,decodeURI(param))}catch(ex){throw new Error("Illegal escape in diff_fromDelta: "+param)}break;case"-":case"=":var n=parseInt(param,10);if(isNaN(n)||n<0){throw new Error("Invalid number in diff_fromDelta: "+param)}var text=text1.substring(pointer,pointer+=n);if(tokens[x].charAt(0)=="="){diffs[diffsLength++]=new diff_match_patch2.Diff(DIFF_EQUAL,text)}else{diffs[diffsLength++]=new diff_match_patch2.Diff(DIFF_DELETE,text)}break;default:if(tokens[x]){throw new Error("Invalid diff operation in diff_fromDelta: "+tokens[x])}}}if(pointer!=text1.length){throw new Error("Delta length ("+pointer+") does not equal source text length ("+text1.length+").")}return diffs};diff_match_patch2.prototype.match_main=function(text,pattern,loc){if(text==null||pattern==null||loc==null){throw new Error("Null input. (match_main)")}loc=Math.max(0,Math.min(loc,text.length));if(text==pattern){return 0}else if(!text.length){return-1}else if(text.substring(loc,loc+pattern.length)==pattern){return loc}else{return this.match_bitap_(text,pattern,loc)}};diff_match_patch2.prototype.match_bitap_=function(text,pattern,loc){if(pattern.length>this.Match_MaxBits){throw new Error("Pattern too long for this browser.")}var s=this.match_alphabet_(pattern);var dmp2=this;function match_bitapScore_(e,x){var accuracy=e/pattern.length;var proximity=Math.abs(loc-x);if(!dmp2.Match_Distance){return proximity?1:accuracy}return accuracy+proximity/dmp2.Match_Distance}__name(match_bitapScore_,"match_bitapScore_");var score_threshold=this.Match_Threshold;var best_loc=text.indexOf(pattern,loc);if(best_loc!=-1){score_threshold=Math.min(match_bitapScore_(0,best_loc),score_threshold);best_loc=text.lastIndexOf(pattern,loc+pattern.length);if(best_loc!=-1){score_threshold=Math.min(match_bitapScore_(0,best_loc),score_threshold)}}var matchmask=1<<pattern.length-1;best_loc=-1;var bin_min,bin_mid;var bin_max=pattern.length+text.length;var last_rd;for(var d=0;d<pattern.length;d++){bin_min=0;bin_mid=bin_max;while(bin_min<bin_mid){if(match_bitapScore_(d,loc+bin_mid)<=score_threshold){bin_min=bin_mid}else{bin_max=bin_mid}bin_mid=Math.floor((bin_max-bin_min)/2+bin_min)}bin_max=bin_mid;var start=Math.max(1,loc-bin_mid+1);var finish=Math.min(loc+bin_mid,text.length)+pattern.length;var rd=Array(finish+2);rd[finish+1]=(1<<d)-1;for(var j=finish;j>=start;j--){var charMatch=s[text.charAt(j-1)];if(d===0){rd[j]=(rd[j+1]<<1|1)&charMatch}else{rd[j]=(rd[j+1]<<1|1)&charMatch|((last_rd[j+1]|last_rd[j])<<1|1)|last_rd[j+1]}if(rd[j]&matchmask){var score=match_bitapScore_(d,j-1);if(score<=score_threshold){score_threshold=score;best_loc=j-1;if(best_loc>loc){start=Math.max(1,2*loc-best_loc)}else{break}}}}if(match_bitapScore_(d+1,loc)>score_threshold){break}last_rd=rd}return best_loc};diff_match_patch2.prototype.match_alphabet_=function(pattern){var s={};for(var i=0;i<pattern.length;i++){s[pattern.charAt(i)]=0}for(var i=0;i<pattern.length;i++){s[pattern.charAt(i)]|=1<<pattern.length-i-1}return s};diff_match_patch2.prototype.patch_addContext_=function(patch2,text){if(text.length==0){return}if(patch2.start2===null){throw Error("patch not initialized")}var pattern=text.substring(patch2.start2,patch2.start2+patch2.length1);var padding=0;while(text.indexOf(pattern)!=text.lastIndexOf(pattern)&&pattern.length<this.Match_MaxBits-this.Patch_Margin-this.Patch_Margin){padding+=this.Patch_Margin;pattern=text.substring(patch2.start2-padding,patch2.start2+patch2.length1+padding)}padding+=this.Patch_Margin;var prefix=text.substring(patch2.start2-padding,patch2.start2);if(prefix){patch2.diffs.unshift(new diff_match_patch2.Diff(DIFF_EQUAL,prefix))}var suffix=text.substring(patch2.start2+patch2.length1,patch2.start2+patch2.length1+padding);if(suffix){patch2.diffs.push(new diff_match_patch2.Diff(DIFF_EQUAL,suffix))}patch2.start1-=prefix.length;patch2.start2-=prefix.length;patch2.length1+=prefix.length+suffix.length;patch2.length2+=prefix.length+suffix.length};diff_match_patch2.prototype.patch_make=function(a,opt_b,opt_c){var text1,diffs;if(typeof a=="string"&&typeof opt_b=="string"&&typeof opt_c=="undefined"){text1=a;diffs=this.diff_main(text1,opt_b,true);if(diffs.length>2){this.diff_cleanupSemantic(diffs);this.diff_cleanupEfficiency(diffs)}}else if(a&&typeof a=="object"&&typeof opt_b=="undefined"&&typeof opt_c=="undefined"){diffs=a;text1=this.diff_text1(diffs)}else if(typeof a=="string"&&opt_b&&typeof opt_b=="object"&&typeof opt_c=="undefined"){text1=a;diffs=opt_b}else if(typeof a=="string"&&typeof opt_b=="string"&&opt_c&&typeof opt_c=="object"){text1=a;diffs=opt_c}else{throw new Error("Unknown call format to patch_make.")}if(diffs.length===0){return[]}var patches=[];var patch2=new diff_match_patch2.patch_obj;var patchDiffLength=0;var char_count1=0;var char_count2=0;var prepatch_text=text1;var postpatch_text=text1;for(var x=0;x<diffs.length;x++){var diff_type=diffs[x][0];var diff_text=diffs[x][1];if(!patchDiffLength&&diff_type!==DIFF_EQUAL){patch2.start1=char_count1;patch2.start2=char_count2}switch(diff_type){case DIFF_INSERT:patch2.diffs[patchDiffLength++]=diffs[x];patch2.length2+=diff_text.length;postpatch_text=postpatch_text.substring(0,char_count2)+diff_text+postpatch_text.substring(char_count2);break;case DIFF_DELETE:patch2.length1+=diff_text.length;patch2.diffs[patchDiffLength++]=diffs[x];postpatch_text=postpatch_text.substring(0,char_count2)+postpatch_text.substring(char_count2+diff_text.length);break;case DIFF_EQUAL:if(diff_text.length<=2*this.Patch_Margin&&patchDiffLength&&diffs.length!=x+1){patch2.diffs[patchDiffLength++]=diffs[x];patch2.length1+=diff_text.length;patch2.length2+=diff_text.length}else if(diff_text.length>=2*this.Patch_Margin){if(patchDiffLength){this.patch_addContext_(patch2,prepatch_text);patches.push(patch2);patch2=new diff_match_patch2.patch_obj;patchDiffLength=0;prepatch_text=postpatch_text;char_count1=char_count2}}break}if(diff_type!==DIFF_INSERT){char_count1+=diff_text.length}if(diff_type!==DIFF_DELETE){char_count2+=diff_text.length}}if(patchDiffLength){this.patch_addContext_(patch2,prepatch_text);patches.push(patch2)}return patches};diff_match_patch2.prototype.patch_deepCopy=function(patches){var patchesCopy=[];for(var x=0;x<patches.length;x++){var patch2=patches[x];var patchCopy=new diff_match_patch2.patch_obj;patchCopy.diffs=[];for(var y=0;y<patch2.diffs.length;y++){patchCopy.diffs[y]=new diff_match_patch2.Diff(patch2.diffs[y][0],patch2.diffs[y][1])}patchCopy.start1=patch2.start1;patchCopy.start2=patch2.start2;patchCopy.length1=patch2.length1;patchCopy.length2=patch2.length2;patchesCopy[x]=patchCopy}return patchesCopy};diff_match_patch2.prototype.patch_apply=function(patches,text){if(patches.length==0){return[text,[]]}patches=this.patch_deepCopy(patches);var nullPadding=this.patch_addPadding(patches);text=nullPadding+text+nullPadding;this.patch_splitMax(patches);var delta=0;var results=[];for(var x=0;x<patches.length;x++){var expected_loc=patches[x].start2+delta;var text1=this.diff_text1(patches[x].diffs);var start_loc;var end_loc=-1;if(text1.length>this.Match_MaxBits){start_loc=this.match_main(text,text1.substring(0,this.Match_MaxBits),expected_loc);if(start_loc!=-1){end_loc=this.match_main(text,text1.substring(text1.length-this.Match_MaxBits),expected_loc+text1.length-this.Match_MaxBits);if(end_loc==-1||start_loc>=end_loc){start_loc=-1}}}else{start_loc=this.match_main(text,text1,expected_loc)}if(start_loc==-1){results[x]=false;delta-=patches[x].length2-patches[x].length1}else{results[x]=true;delta=start_loc-expected_loc;var text2;if(end_loc==-1){text2=text.substring(start_loc,start_loc+text1.length)}else{text2=text.substring(start_loc,end_loc+this.Match_MaxBits)}if(text1==text2){text=text.substring(0,start_loc)+this.diff_text2(patches[x].diffs)+text.substring(start_loc+text1.length)}else{var diffs=this.diff_main(text1,text2,false);if(text1.length>this.Match_MaxBits&&this.diff_levenshtein(diffs)/text1.length>this.Patch_DeleteThreshold){results[x]=false}else{this.diff_cleanupSemanticLossless(diffs);var index1=0;var index2;for(var y=0;y<patches[x].diffs.length;y++){var mod=patches[x].diffs[y];if(mod[0]!==DIFF_EQUAL){index2=this.diff_xIndex(diffs,index1)}if(mod[0]===DIFF_INSERT){text=text.substring(0,start_loc+index2)+mod[1]+text.substring(start_loc+index2)}else if(mod[0]===DIFF_DELETE){text=text.substring(0,start_loc+index2)+text.substring(start_loc+this.diff_xIndex(diffs,index1+mod[1].length))}if(mod[0]!==DIFF_DELETE){index1+=mod[1].length}}}}}}text=text.substring(nullPadding.length,text.length-nullPadding.length);return[text,results]};diff_match_patch2.prototype.patch_addPadding=function(patches){var paddingLength=this.Patch_Margin;var nullPadding="";for(var x=1;x<=paddingLength;x++){nullPadding+=String.fromCharCode(x)}for(var x=0;x<patches.length;x++){patches[x].start1+=paddingLength;patches[x].start2+=paddingLength}var patch2=patches[0];var diffs=patch2.diffs;if(diffs.length==0||diffs[0][0]!=DIFF_EQUAL){diffs.unshift(new diff_match_patch2.Diff(DIFF_EQUAL,nullPadding));patch2.start1-=paddingLength;patch2.start2-=paddingLength;patch2.length1+=paddingLength;patch2.length2+=paddingLength}else if(paddingLength>diffs[0][1].length){var extraLength=paddingLength-diffs[0][1].length;diffs[0][1]=nullPadding.substring(diffs[0][1].length)+diffs[0][1];patch2.start1-=extraLength;patch2.start2-=extraLength;patch2.length1+=extraLength;patch2.length2+=extraLength}patch2=patches[patches.length-1];diffs=patch2.diffs;if(diffs.length==0||diffs[diffs.length-1][0]!=DIFF_EQUAL){diffs.push(new diff_match_patch2.Diff(DIFF_EQUAL,nullPadding));patch2.length1+=paddingLength;patch2.length2+=paddingLength}else if(paddingLength>diffs[diffs.length-1][1].length){var extraLength=paddingLength-diffs[diffs.length-1][1].length;diffs[diffs.length-1][1]+=nullPadding.substring(0,extraLength);patch2.length1+=extraLength;patch2.length2+=extraLength}return nullPadding};diff_match_patch2.prototype.patch_splitMax=function(patches){var patch_size=this.Match_MaxBits;for(var x=0;x<patches.length;x++){if(patches[x].length1<=patch_size){continue}var bigpatch=patches[x];patches.splice(x--,1);var start1=bigpatch.start1;var start2=bigpatch.start2;var precontext="";while(bigpatch.diffs.length!==0){var patch2=new diff_match_patch2.patch_obj;var empty=true;patch2.start1=start1-precontext.length;patch2.start2=start2-precontext.length;if(precontext!==""){patch2.length1=patch2.length2=precontext.length;patch2.diffs.push(new diff_match_patch2.Diff(DIFF_EQUAL,precontext))}while(bigpatch.diffs.length!==0&&patch2.length1<patch_size-this.Patch_Margin){var diff_type=bigpatch.diffs[0][0];var diff_text=bigpatch.diffs[0][1];if(diff_type===DIFF_INSERT){patch2.length2+=diff_text.length;start2+=diff_text.length;patch2.diffs.push(bigpatch.diffs.shift());empty=false}else if(diff_type===DIFF_DELETE&&patch2.diffs.length==1&&patch2.diffs[0][0]==DIFF_EQUAL&&diff_text.length>2*patch_size){patch2.length1+=diff_text.length;start1+=diff_text.length;empty=false;patch2.diffs.push(new diff_match_patch2.Diff(diff_type,diff_text));bigpatch.diffs.shift()}else{diff_text=diff_text.substring(0,patch_size-patch2.length1-this.Patch_Margin);patch2.length1+=diff_text.length;start1+=diff_text.length;if(diff_type===DIFF_EQUAL){patch2.length2+=diff_text.length;start2+=diff_text.length}else{empty=false}patch2.diffs.push(new diff_match_patch2.Diff(diff_type,diff_text));if(diff_text==bigpatch.diffs[0][1]){bigpatch.diffs.shift()}else{bigpatch.diffs[0][1]=bigpatch.diffs[0][1].substring(diff_text.length)}}}precontext=this.diff_text2(patch2.diffs);precontext=precontext.substring(precontext.length-this.Patch_Margin);var postcontext=this.diff_text1(bigpatch.diffs).substring(0,this.Patch_Margin);if(postcontext!==""){patch2.length1+=postcontext.length;patch2.length2+=postcontext.length;if(patch2.diffs.length!==0&&patch2.diffs[patch2.diffs.length-1][0]===DIFF_EQUAL){patch2.diffs[patch2.diffs.length-1][1]+=postcontext}else{patch2.diffs.push(new diff_match_patch2.Diff(DIFF_EQUAL,postcontext))}}if(!empty){patches.splice(++x,0,patch2)}}}};diff_match_patch2.prototype.patch_toText=function(patches){var text=[];for(var x=0;x<patches.length;x++){text[x]=patches[x]}return text.join("")};diff_match_patch2.prototype.patch_fromText=function(textline){var patches=[];if(!textline){return patches}var text=textline.split("\n");var textPointer=0;var patchHeader=/^@@ -(\d+),?(\d*) \+(\d+),?(\d*) @@$/;while(textPointer<text.length){var m=text[textPointer].match(patchHeader);if(!m){throw new Error("Invalid patch string: "+text[textPointer])}var patch2=new diff_match_patch2.patch_obj;patches.push(patch2);patch2.start1=parseInt(m[1],10);if(m[2]===""){patch2.start1--;patch2.length1=1}else if(m[2]=="0"){patch2.length1=0}else{patch2.start1--;patch2.length1=parseInt(m[2],10)}patch2.start2=parseInt(m[3],10);if(m[4]===""){patch2.start2--;patch2.length2=1}else if(m[4]=="0"){patch2.length2=0}else{patch2.start2--;patch2.length2=parseInt(m[4],10)}textPointer++;while(textPointer<text.length){var sign=text[textPointer].charAt(0);try{var line=decodeURI(text[textPointer].substring(1))}catch(ex){throw new Error("Illegal escape in patch_fromText: "+line)}if(sign=="-"){patch2.diffs.push(new diff_match_patch2.Diff(DIFF_DELETE,line))}else if(sign=="+"){patch2.diffs.push(new diff_match_patch2.Diff(DIFF_INSERT,line))}else if(sign==" "){patch2.diffs.push(new diff_match_patch2.Diff(DIFF_EQUAL,line))}else if(sign=="@"){break}else if(sign==="");else{throw new Error('Invalid patch mode "'+sign+'" in: '+line)}textPointer++}}return patches};diff_match_patch2.patch_obj=function(){this.diffs=[];this.start1=null;this.start2=null;this.length1=0;this.length2=0};diff_match_patch2.patch_obj.prototype.toString=function(){var coords1,coords2;if(this.length1===0){coords1=this.start1+",0"}else if(this.length1==1){coords1=this.start1+1}else{coords1=this.start1+1+","+this.length1}if(this.length2===0){coords2=this.start2+",0"}else if(this.length2==1){coords2=this.start2+1}else{coords2=this.start2+1+","+this.length2}var text=["@@ -"+coords1+" +"+coords2+" @@\n"];var op;for(var x=0;x<this.diffs.length;x++){switch(this.diffs[x][0]){case DIFF_INSERT:op="+";break;case DIFF_DELETE:op="-";break;case DIFF_EQUAL:op=" ";break}text[x+1]=op+encodeURI(this.diffs[x][1])+"\n"}return text.join("").replace(/%20/g," ")};module2.exports=diff_match_patch2;module2.exports["diff_match_patch"]=diff_match_patch2;module2.exports["DIFF_DELETE"]=DIFF_DELETE;module2.exports["DIFF_INSERT"]=DIFF_INSERT;module2.exports["DIFF_EQUAL"]=DIFF_EQUAL})(diffMatchPatch);var diffMatchPatchExports=diffMatchPatch.exports;const dmp=getDefaultExportFromCjs(diffMatchPatchExports);var ansiStyles$1={exports:{}};var colorName;var hasRequiredColorName;function requireColorName(){if(hasRequiredColorName)return colorName;hasRequiredColorName=1;colorName={"aliceblue":[240,248,255],"antiquewhite":[250,235,215],"aqua":[0,255,255],"aquamarine":[127,255,212],"azure":[240,255,255],"beige":[245,245,220],"bisque":[255,228,196],"black":[0,0,0],"blanchedalmond":[255,235,205],"blue":[0,0,255],"blueviolet":[138,43,226],"brown":[165,42,42],"burlywood":[222,184,135],"cadetblue":[95,158,160],"chartreuse":[127,255,0],"chocolate":[210,105,30],"coral":[255,127,80],"cornflowerblue":[100,149,237],"cornsilk":[255,248,220],"crimson":[220,20,60],"cyan":[0,255,255],"darkblue":[0,0,139],"darkcyan":[0,139,139],"darkgoldenrod":[184,134,11],"darkgray":[169,169,169],"darkgreen":[0,100,0],"darkgrey":[169,169,169],"darkkhaki":[189,183,107],"darkmagenta":[139,0,139],"darkolivegreen":[85,107,47],"darkorange":[255,140,0],"darkorchid":[153,50,204],"darkred":[139,0,0],"darksalmon":[233,150,122],"darkseagreen":[143,188,143],"darkslateblue":[72,61,139],"darkslategray":[47,79,79],"darkslategrey":[47,79,79],"darkturquoise":[0,206,209],"darkviolet":[148,0,211],"deeppink":[255,20,147],"deepskyblue":[0,191,255],"dimgray":[105,105,105],"dimgrey":[105,105,105],"dodgerblue":[30,144,255],"firebrick":[178,34,34],"floralwhite":[255,250,240],"forestgreen":[34,139,34],"fuchsia":[255,0,255],"gainsboro":[220,220,220],"ghostwhite":[248,248,255],"gold":[255,215,0],"goldenrod":[218,165,32],"gray":[128,128,128],"green":[0,128,0],"greenyellow":[173,255,47],"grey":[128,128,128],"honeydew":[240,255,240],"hotpink":[255,105,180],"indianred":[205,92,92],"indigo":[75,0,130],"ivory":[255,255,240],"khaki":[240,230,140],"lavender":[230,230,250],"lavenderblush":[255,240,245],"lawngreen":[124,252,0],"lemonchiffon":[255,250,205],"lightblue":[173,216,230],"lightcoral":[240,128,128],"lightcyan":[224,255,255],"lightgoldenrodyellow":[250,250,210],"lightgray":[211,211,211],"lightgreen":[144,238,144],"lightgrey":[211,211,211],"lightpink":[255,182,193],"lightsalmon":[255,160,122],"lightseagreen":[32,178,170],"lightskyblue":[135,206,250],"lightslategray":[119,136,153],"lightslategrey":[119,136,153],"lightsteelblue":[176,196,222],"lightyellow":[255,255,224],"lime":[0,255,0],"limegreen":[50,205,50],"linen":[250,240,230],"magenta":[255,0,255],"maroon":[128,0,0],"mediumaquamarine":[102,205,170],"mediumblue":[0,0,205],"mediumorchid":[186,85,211],"mediumpurple":[147,112,219],"mediumseagreen":[60,179,113],"mediumslateblue":[123,104,238],"mediumspringgreen":[0,250,154],"mediumturquoise":[72,209,204],"mediumvioletred":[199,21,133],"midnightblue":[25,25,112],"mintcream":[245,255,250],"mistyrose":[255,228,225],"moccasin":[255,228,181],"navajowhite":[255,222,173],"navy":[0,0,128],"oldlace":[253,245,230],"olive":[128,128,0],"olivedrab":[107,142,35],"orange":[255,165,0],"orangered":[255,69,0],"orchid":[218,112,214],"palegoldenrod":[238,232,170],"palegreen":[152,251,152],"paleturquoise":[175,238,238],"palevioletred":[219,112,147],"papayawhip":[255,239,213],"peachpuff":[255,218,185],"peru":[205,133,63],"pink":[255,192,203],"plum":[221,160,221],"powderblue":[176,224,230],"purple":[128,0,128],"rebeccapurple":[102,51,153],"red":[255,0,0],"rosybrown":[188,143,143],"royalblue":[65,105,225],"saddlebrown":[139,69,19],"salmon":[250,128,114],"sandybrown":[244,164,96],"seagreen":[46,139,87],"seashell":[255,245,238],"sienna":[160,82,45],"silver":[192,192,192],"skyblue":[135,206,235],"slateblue":[106,90,205],"slategray":[112,128,144],"slategrey":[112,128,144],"snow":[255,250,250],"springgreen":[0,255,127],"steelblue":[70,130,180],"tan":[210,180,140],"teal":[0,128,128],"thistle":[216,191,216],"tomato":[255,99,71],"turquoise":[64,224,208],"violet":[238,130,238],"wheat":[245,222,179],"white":[255,255,255],"whitesmoke":[245,245,245],"yellow":[255,255,0],"yellowgreen":[154,205,50]};return colorName}__name(requireColorName,"requireColorName");var conversions;var hasRequiredConversions;function requireConversions(){if(hasRequiredConversions)return conversions;hasRequiredConversions=1;const cssKeywords=requireColorName();const reverseKeywords={};for(const key of Object.keys(cssKeywords)){reverseKeywords[cssKeywords[key]]=key}const convert={rgb:{channels:3,labels:"rgb"},hsl:{channels:3,labels:"hsl"},hsv:{channels:3,labels:"hsv"},hwb:{channels:3,labels:"hwb"},cmyk:{channels:4,labels:"cmyk"},xyz:{channels:3,labels:"xyz"},lab:{channels:3,labels:"lab"},lch:{channels:3,labels:"lch"},hex:{channels:1,labels:["hex"]},keyword:{channels:1,labels:["keyword"]},ansi16:{channels:1,labels:["ansi16"]},ansi256:{channels:1,labels:["ansi256"]},hcg:{channels:3,labels:["h","c","g"]},apple:{channels:3,labels:["r16","g16","b16"]},gray:{channels:1,labels:["gray"]}};conversions=convert;for(const model of Object.keys(convert)){if(!("channels"in convert[model])){throw new Error("missing channels property: "+model)}if(!("labels"in convert[model])){throw new Error("missing channel labels property: "+model)}if(convert[model].labels.length!==convert[model].channels){throw new Error("channel and label counts mismatch: "+model)}const{channels,labels}=convert[model];delete convert[model].channels;delete convert[model].labels;Object.defineProperty(convert[model],"channels",{value:channels});Object.defineProperty(convert[model],"labels",{value:labels})}convert.rgb.hsl=function(rgb){const r=rgb[0]/255;const g=rgb[1]/255;const b=rgb[2]/255;const min=Math.min(r,g,b);const max=Math.max(r,g,b);const delta=max-min;let h;let s;if(max===min){h=0}else if(r===max){h=(g-b)/delta}else if(g===max){h=2+(b-r)/delta}else if(b===max){h=4+(r-g)/delta}h=Math.min(h*60,360);if(h<0){h+=360}const l=(min+max)/2;if(max===min){s=0}else if(l<=.5){s=delta/(max+min)}else{s=delta/(2-max-min)}return[h,s*100,l*100]};convert.rgb.hsv=function(rgb){let rdif;let gdif;let bdif;let h;let s;const r=rgb[0]/255;const g=rgb[1]/255;const b=rgb[2]/255;const v=Math.max(r,g,b);const diff2=v-Math.min(r,g,b);const diffc=__name(function(c){return(v-c)/6/diff2+1/2},"diffc");if(diff2===0){h=0;s=0}else{s=diff2/v;rdif=diffc(r);gdif=diffc(g);bdif=diffc(b);if(r===v){h=bdif-gdif}else if(g===v){h=1/3+rdif-bdif}else if(b===v){h=2/3+gdif-rdif}if(h<0){h+=1}else if(h>1){h-=1}}return[h*360,s*100,v*100]};convert.rgb.hwb=function(rgb){const r=rgb[0];const g=rgb[1];let b=rgb[2];const h=convert.rgb.hsl(rgb)[0];const w=1/255*Math.min(r,Math.min(g,b));b=1-1/255*Math.max(r,Math.max(g,b));return[h,w*100,b*100]};convert.rgb.cmyk=function(rgb){const r=rgb[0]/255;const g=rgb[1]/255;const b=rgb[2]/255;const k=Math.min(1-r,1-g,1-b);const c=(1-r-k)/(1-k)||0;const m=(1-g-k)/(1-k)||0;const y=(1-b-k)/(1-k)||0;return[c*100,m*100,y*100,k*100]};function comparativeDistance(x,y){return __pow(x[0]-y[0],2)+__pow(x[1]-y[1],2)+__pow(x[2]-y[2],2)}__name(comparativeDistance,"comparativeDistance");convert.rgb.keyword=function(rgb){const reversed=reverseKeywords[rgb];if(reversed){return reversed}let currentClosestDistance=Infinity;let currentClosestKeyword;for(const keyword of Object.keys(cssKeywords)){const value=cssKeywords[keyword];const distance=comparativeDistance(rgb,value);if(distance<currentClosestDistance){currentClosestDistance=distance;currentClosestKeyword=keyword}}return currentClosestKeyword};convert.keyword.rgb=function(keyword){return cssKeywords[keyword]};convert.rgb.xyz=function(rgb){let r=rgb[0]/255;let g=rgb[1]/255;let b=rgb[2]/255;r=r>.04045?__pow((r+.055)/1.055,2.4):r/12.92;g=g>.04045?__pow((g+.055)/1.055,2.4):g/12.92;b=b>.04045?__pow((b+.055)/1.055,2.4):b/12.92;const x=r*.4124+g*.3576+b*.1805;const y=r*.2126+g*.7152+b*.0722;const z=r*.0193+g*.1192+b*.9505;return[x*100,y*100,z*100]};convert.rgb.lab=function(rgb){const xyz=convert.rgb.xyz(rgb);let x=xyz[0];let y=xyz[1];let z=xyz[2];x/=95.047;y/=100;z/=108.883;x=x>.008856?__pow(x,1/3):7.787*x+16/116;y=y>.008856?__pow(y,1/3):7.787*y+16/116;z=z>.008856?__pow(z,1/3):7.787*z+16/116;const l=116*y-16;const a=500*(x-y);const b=200*(y-z);return[l,a,b]};convert.hsl.rgb=function(hsl){const h=hsl[0]/360;const s=hsl[1]/100;const l=hsl[2]/100;let t2;let t3;let val;if(s===0){val=l*255;return[val,val,val]}if(l<.5){t2=l*(1+s)}else{t2=l+s-l*s}const t1=2*l-t2;const rgb=[0,0,0];for(let i=0;i<3;i++){t3=h+1/3*-(i-1);if(t3<0){t3++}if(t3>1){t3--}if(6*t3<1){val=t1+(t2-t1)*6*t3}else if(2*t3<1){val=t2}else if(3*t3<2){val=t1+(t2-t1)*(2/3-t3)*6}else{val=t1}rgb[i]=val*255}return rgb};convert.hsl.hsv=function(hsl){const h=hsl[0];let s=hsl[1]/100;let l=hsl[2]/100;let smin=s;const lmin=Math.max(l,.01);l*=2;s*=l<=1?l:2-l;smin*=lmin<=1?lmin:2-lmin;const v=(l+s)/2;const sv=l===0?2*smin/(lmin+smin):2*s/(l+s);return[h,sv*100,v*100]};convert.hsv.rgb=function(hsv){const h=hsv[0]/60;const s=hsv[1]/100;let v=hsv[2]/100;const hi=Math.floor(h)%6;const f=h-Math.floor(h);const p=255*v*(1-s);const q=255*v*(1-s*f);const t=255*v*(1-s*(1-f));v*=255;switch(hi){case 0:return[v,t,p];case 1:return[q,v,p];case 2:return[p,v,t];case 3:return[p,q,v];case 4:return[t,p,v];case 5:return[v,p,q]}};convert.hsv.hsl=function(hsv){const h=hsv[0];const s=hsv[1]/100;const v=hsv[2]/100;const vmin=Math.max(v,.01);let sl;let l;l=(2-s)*v;const lmin=(2-s)*vmin;sl=s*vmin;sl/=lmin<=1?lmin:2-lmin;sl=sl||0;l/=2;return[h,sl*100,l*100]};convert.hwb.rgb=function(hwb){const h=hwb[0]/360;let wh=hwb[1]/100;let bl=hwb[2]/100;const ratio=wh+bl;let f;if(ratio>1){wh/=ratio;bl/=ratio}const i=Math.floor(6*h);const v=1-bl;f=6*h-i;if((i&1)!==0){f=1-f}const n=wh+f*(v-wh);let r;let g;let b;switch(i){default:case 6:case 0:r=v;g=n;b=wh;break;case 1:r=n;g=v;b=wh;break;case 2:r=wh;g=v;b=n;break;case 3:r=wh;g=n;b=v;break;case 4:r=n;g=wh;b=v;break;case 5:r=v;g=wh;b=n;break}return[r*255,g*255,b*255]};convert.cmyk.rgb=function(cmyk){const c=cmyk[0]/100;const m=cmyk[1]/100;const y=cmyk[2]/100;const k=cmyk[3]/100;const r=1-Math.min(1,c*(1-k)+k);const g=1-Math.min(1,m*(1-k)+k);const b=1-Math.min(1,y*(1-k)+k);return[r*255,g*255,b*255]};convert.xyz.rgb=function(xyz){const x=xyz[0]/100;const y=xyz[1]/100;const z=xyz[2]/100;let r;let g;let b;r=x*3.2406+y*-1.5372+z*-.4986;g=x*-.9689+y*1.8758+z*.0415;b=x*.0557+y*-.204+z*1.057;r=r>.0031308?1.055*__pow(r,1/2.4)-.055:r*12.92;g=g>.0031308?1.055*__pow(g,1/2.4)-.055:g*12.92;b=b>.0031308?1.055*__pow(b,1/2.4)-.055:b*12.92;r=Math.min(Math.max(0,r),1);g=Math.min(Math.max(0,g),1);b=Math.min(Math.max(0,b),1);return[r*255,g*255,b*255]};convert.xyz.lab=function(xyz){let x=xyz[0];let y=xyz[1];let z=xyz[2];x/=95.047;y/=100;z/=108.883;x=x>.008856?__pow(x,1/3):7.787*x+16/116;y=y>.008856?__pow(y,1/3):7.787*y+16/116;z=z>.008856?__pow(z,1/3):7.787*z+16/116;const l=116*y-16;const a=500*(x-y);const b=200*(y-z);return[l,a,b]};convert.lab.xyz=function(lab){const l=lab[0];const a=lab[1];const b=lab[2];let x;let y;let z;y=(l+16)/116;x=a/500+y;z=y-b/200;const y2=__pow(y,3);const x2=__pow(x,3);const z2=__pow(z,3);y=y2>.008856?y2:(y-16/116)/7.787;x=x2>.008856?x2:(x-16/116)/7.787;z=z2>.008856?z2:(z-16/116)/7.787;x*=95.047;y*=100;z*=108.883;return[x,y,z]};convert.lab.lch=function(lab){const l=lab[0];const a=lab[1];const b=lab[2];let h;const hr=Math.atan2(b,a);h=hr*360/2/Math.PI;if(h<0){h+=360}const c=Math.sqrt(a*a+b*b);return[l,c,h]};convert.lch.lab=function(lch){const l=lch[0];const c=lch[1];const h=lch[2];const hr=h/360*2*Math.PI;const a=c*Math.cos(hr);const b=c*Math.sin(hr);return[l,a,b]};convert.rgb.ansi16=function(args,saturation=null){const[r,g,b]=args;let value=saturation===null?convert.rgb.hsv(args)[2]:saturation;value=Math.round(value/50);if(value===0){return 30}let ansi=30+(Math.round(b/255)<<2|Math.round(g/255)<<1|Math.round(r/255));if(value===2){ansi+=60}return ansi};convert.hsv.ansi16=function(args){return convert.rgb.ansi16(convert.hsv.rgb(args),args[2])};convert.rgb.ansi256=function(args){const r=args[0];const g=args[1];const b=args[2];if(r===g&&g===b){if(r<8){return 16}if(r>248){return 231}return Math.round((r-8)/247*24)+232}const ansi=16+36*Math.round(r/255*5)+6*Math.round(g/255*5)+Math.round(b/255*5);return ansi};convert.ansi16.rgb=function(args){let color=args%10;if(color===0||color===7){if(args>50){color+=3.5}color=color/10.5*255;return[color,color,color]}const mult=(~~(args>50)+1)*.5;const r=(color&1)*mult*255;const g=(color>>1&1)*mult*255;const b=(color>>2&1)*mult*255;return[r,g,b]};convert.ansi256.rgb=function(args){if(args>=232){const c=(args-232)*10+8;return[c,c,c]}args-=16;let rem;const r=Math.floor(args/36)/5*255;const g=Math.floor((rem=args%36)/6)/5*255;const b=rem%6/5*255;return[r,g,b]};convert.rgb.hex=function(args){const integer=((Math.round(args[0])&255)<<16)+((Math.round(args[1])&255)<<8)+(Math.round(args[2])&255);const string=integer.toString(16).toUpperCase();return"000000".substring(string.length)+string};convert.hex.rgb=function(args){const match=args.toString(16).match(/[a-f0-9]{6}|[a-f0-9]{3}/i);if(!match){return[0,0,0]}let colorString=match[0];if(match[0].length===3){colorString=colorString.split("").map(char=>{return char+char}).join("")}const integer=parseInt(colorString,16);const r=integer>>16&255;const g=integer>>8&255;const b=integer&255;return[r,g,b]};convert.rgb.hcg=function(rgb){const r=rgb[0]/255;const g=rgb[1]/255;const b=rgb[2]/255;const max=Math.max(Math.max(r,g),b);const min=Math.min(Math.min(r,g),b);const chroma=max-min;let grayscale;let hue;if(chroma<1){grayscale=min/(1-chroma)}else{grayscale=0}if(chroma<=0){hue=0}else if(max===r){hue=(g-b)/chroma%6}else if(max===g){hue=2+(b-r)/chroma}else{hue=4+(r-g)/chroma}hue/=6;hue%=1;return[hue*360,chroma*100,grayscale*100]};convert.hsl.hcg=function(hsl){const s=hsl[1]/100;const l=hsl[2]/100;const c=l<.5?2*s*l:2*s*(1-l);let f=0;if(c<1){f=(l-.5*c)/(1-c)}return[hsl[0],c*100,f*100]};convert.hsv.hcg=function(hsv){const s=hsv[1]/100;const v=hsv[2]/100;const c=s*v;let f=0;if(c<1){f=(v-c)/(1-c)}return[hsv[0],c*100,f*100]};convert.hcg.rgb=function(hcg){const h=hcg[0]/360;const c=hcg[1]/100;const g=hcg[2]/100;if(c===0){return[g*255,g*255,g*255]}const pure=[0,0,0];const hi=h%1*6;const v=hi%1;const w=1-v;let mg=0;switch(Math.floor(hi)){case 0:pure[0]=1;pure[1]=v;pure[2]=0;break;case 1:pure[0]=w;pure[1]=1;pure[2]=0;break;case 2:pure[0]=0;pure[1]=1;pure[2]=v;break;case 3:pure[0]=0;pure[1]=w;pure[2]=1;break;case 4:pure[0]=v;pure[1]=0;pure[2]=1;break;default:pure[0]=1;pure[1]=0;pure[2]=w}mg=(1-c)*g;return[(c*pure[0]+mg)*255,(c*pure[1]+mg)*255,(c*pure[2]+mg)*255]};convert.hcg.hsv=function(hcg){const c=hcg[1]/100;const g=hcg[2]/100;const v=c+g*(1-c);let f=0;if(v>0){f=c/v}return[hcg[0],f*100,v*100]};convert.hcg.hsl=function(hcg){const c=hcg[1]/100;const g=hcg[2]/100;const l=g*(1-c)+.5*c;let s=0;if(l>0&&l<.5){s=c/(2*l)}else if(l>=.5&&l<1){s=c/(2*(1-l))}return[hcg[0],s*100,l*100]};convert.hcg.hwb=function(hcg){const c=hcg[1]/100;const g=hcg[2]/100;const v=c+g*(1-c);return[hcg[0],(v-c)*100,(1-v)*100]};convert.hwb.hcg=function(hwb){const w=hwb[1]/100;const b=hwb[2]/100;const v=1-b;const c=v-w;let g=0;if(c<1){g=(v-c)/(1-c)}return[hwb[0],c*100,g*100]};convert.apple.rgb=function(apple){return[apple[0]/65535*255,apple[1]/65535*255,apple[2]/65535*255]};convert.rgb.apple=function(rgb){return[rgb[0]/255*65535,rgb[1]/255*65535,rgb[2]/255*65535]};convert.gray.rgb=function(args){return[args[0]/100*255,args[0]/100*255,args[0]/100*255]};convert.gray.hsl=function(args){return[0,0,args[0]]};convert.gray.hsv=convert.gray.hsl;convert.gray.hwb=function(gray){return[0,100,gray[0]]};convert.gray.cmyk=function(gray){return[0,0,0,gray[0]]};convert.gray.lab=function(gray){return[gray[0],0,0]};convert.gray.hex=function(gray){const val=Math.round(gray[0]/100*255)&255;const integer=(val<<16)+(val<<8)+val;const string=integer.toString(16).toUpperCase();return"000000".substring(string.length)+string};convert.rgb.gray=function(rgb){const val=(rgb[0]+rgb[1]+rgb[2])/3;return[val/255*100]};return conversions}__name(requireConversions,"requireConversions");var route;var hasRequiredRoute;function requireRoute(){if(hasRequiredRoute)return route;hasRequiredRoute=1;const conversions2=requireConversions();function buildGraph(){const graph={};const models=Object.keys(conversions2);for(let len=models.length,i=0;i<len;i++){graph[models[i]]={distance:-1,parent:null}}return graph}__name(buildGraph,"buildGraph");function deriveBFS(fromModel){const graph=buildGraph();const queue=[fromModel];graph[fromModel].distance=0;while(queue.length){const current=queue.pop();const adjacents=Object.keys(conversions2[current]);for(let len=adjacents.length,i=0;i<len;i++){const adjacent=adjacents[i];const node=graph[adjacent];if(node.distance===-1){node.distance=graph[current].distance+1;node.parent=current;queue.unshift(adjacent)}}}return graph}__name(deriveBFS,"deriveBFS");function link(from,to){return function(args){return to(from(args))}}__name(link,"link");function wrapConversion(toModel,graph){const path=[graph[toModel].parent,toModel];let fn=conversions2[graph[toModel].parent][toModel];let cur=graph[toModel].parent;while(graph[cur].parent){path.unshift(graph[cur].parent);fn=link(conversions2[graph[cur].parent][cur],fn);cur=graph[cur].parent}fn.conversion=path;return fn}__name(wrapConversion,"wrapConversion");route=__name(function(fromModel){const graph=deriveBFS(fromModel);const conversion={};const models=Object.keys(graph);for(let len=models.length,i=0;i<len;i++){const toModel=models[i];const node=graph[toModel];if(node.parent===null){continue}conversion[toModel]=wrapConversion(toModel,graph)}return conversion},"route");return route}__name(requireRoute,"requireRoute");var colorConvert;var hasRequiredColorConvert;function requireColorConvert(){if(hasRequiredColorConvert)return colorConvert;hasRequiredColorConvert=1;const conversions2=requireConversions();const route2=requireRoute();const convert={};const models=Object.keys(conversions2);function wrapRaw(fn){const wrappedFn=__name(function(...args){const arg0=args[0];if(arg0===void 0||arg0===null){return arg0}if(arg0.length>1){args=arg0}return fn(args)},"wrappedFn");if("conversion"in fn){wrappedFn.conversion=fn.conversion}return wrappedFn}__name(wrapRaw,"wrapRaw");function wrapRounded(fn){const wrappedFn=__name(function(...args){const arg0=args[0];if(arg0===void 0||arg0===null){return arg0}if(arg0.length>1){args=arg0}const result=fn(args);if(typeof result==="object"){for(let len=result.length,i=0;i<len;i++){result[i]=Math.round(result[i])}}return result},"wrappedFn");if("conversion"in fn){wrappedFn.conversion=fn.conversion}return wrappedFn}__name(wrapRounded,"wrapRounded");models.forEach(fromModel=>{convert[fromModel]={};Object.defineProperty(convert[fromModel],"channels",{value:conversions2[fromModel].channels});Object.defineProperty(convert[fromModel],"labels",{value:conversions2[fromModel].labels});const routes=route2(fromModel);const routeModels=Object.keys(routes);routeModels.forEach(toModel=>{const fn=routes[toModel];convert[fromModel][toModel]=wrapRounded(fn);convert[fromModel][toModel].raw=wrapRaw(fn)})});colorConvert=convert;return colorConvert}__name(requireColorConvert,"requireColorConvert");ansiStyles$1.exports;(function(module2){const wrapAnsi16=__name((fn,offset)=>(...args)=>{const code=fn(...args);return`\x1B[${code+offset}m`},"wrapAnsi16");const wrapAnsi256=__name((fn,offset)=>(...args)=>{const code=fn(...args);return`\x1B[${38+offset};5;${code}m`},"wrapAnsi256");const wrapAnsi16m=__name((fn,offset)=>(...args)=>{const rgb=fn(...args);return`\x1B[${38+offset};2;${rgb[0]};${rgb[1]};${rgb[2]}m`},"wrapAnsi16m");const ansi2ansi=__name(n=>n,"ansi2ansi");const rgb2rgb=__name((r,g,b)=>[r,g,b],"rgb2rgb");const setLazyProperty=__name((object,property,get4)=>{Object.defineProperty(object,property,{get:()=>{const value=get4();Object.defineProperty(object,property,{value,enumerable:true,configurable:true});return value},enumerable:true,configurable:true})},"setLazyProperty");let colorConvert2;const makeDynamicStyles=__name((wrap,targetSpace,identity,isBackground)=>{if(colorConvert2===void 0){colorConvert2=requireColorConvert()}const offset=isBackground?10:0;const styles2={};for(const[sourceSpace,suite]of Object.entries(colorConvert2)){const name=sourceSpace==="ansi16"?"ansi":sourceSpace;if(sourceSpace===targetSpace){styles2[name]=wrap(identity,offset)}else if(typeof suite==="object"){styles2[name]=wrap(suite[targetSpace],offset)}}return styles2},"makeDynamicStyles");function assembleStyles(){const codes=new Map;const styles2={modifier:{reset:[0,0],bold:[1,22],dim:[2,22],italic:[3,23],underline:[4,24],inverse:[7,27],hidden:[8,28],strikethrough:[9,29]},color:{black:[30,39],red:[31,39],green:[32,39],yellow:[33,39],blue:[34,39],magenta:[35,39],cyan:[36,39],white:[37,39],blackBright:[90,39],redBright:[91,39],greenBright:[92,39],yellowBright:[93,39],blueBright:[94,39],magentaBright:[95,39],cyanBright:[96,39],whiteBright:[97,39]},bgColor:{bgBlack:[40,49],bgRed:[41,49],bgGreen:[42,49],bgYellow:[43,49],bgBlue:[44,49],bgMagenta:[45,49],bgCyan:[46,49],bgWhite:[47,49],bgBlackBright:[100,49],bgRedBright:[101,49],bgGreenBright:[102,49],bgYellowBright:[103,49],bgBlueBright:[104,49],bgMagentaBright:[105,49],bgCyanBright:[106,49],bgWhiteBright:[107,49]}};styles2.color.gray=styles2.color.blackBright;styles2.bgColor.bgGray=styles2.bgColor.bgBlackBright;styles2.color.grey=styles2.color.blackBright;styles2.bgColor.bgGrey=styles2.bgColor.bgBlackBright;for(const[groupName,group]of Object.entries(styles2)){for(const[styleName,style]of Object.entries(group)){styles2[styleName]={open:`\x1B[${style[0]}m`,close:`\x1B[${style[1]}m`};group[styleName]=styles2[styleName];codes.set(style[0],style[1])}Object.defineProperty(styles2,groupName,{value:group,enumerable:false})}Object.defineProperty(styles2,"codes",{value:codes,enumerable:false});styles2.color.close="\x1B[39m";styles2.bgColor.close="\x1B[49m";setLazyProperty(styles2.color,"ansi",()=>makeDynamicStyles(wrapAnsi16,"ansi16",ansi2ansi,false));setLazyProperty(styles2.color,"ansi256",()=>makeDynamicStyles(wrapAnsi256,"ansi256",ansi2ansi,false));setLazyProperty(styles2.color,"ansi16m",()=>makeDynamicStyles(wrapAnsi16m,"rgb",rgb2rgb,false));setLazyProperty(styles2.bgColor,"ansi",()=>makeDynamicStyles(wrapAnsi16,"ansi16",ansi2ansi,true));setLazyProperty(styles2.bgColor,"ansi256",()=>makeDynamicStyles(wrapAnsi256,"ansi256",ansi2ansi,true));setLazyProperty(styles2.bgColor,"ansi16m",()=>makeDynamicStyles(wrapAnsi16m,"rgb",rgb2rgb,true));return styles2}__name(assembleStyles,"assembleStyles");Object.defineProperty(module2,"exports",{enumerable:true,get:assembleStyles})})(ansiStyles$1);var ansiStylesExports=ansiStyles$1.exports;var browser={stdout:false,stderr:false};const stringReplaceAll$1=__name((string,substring,replacer)=>{let index2=string.indexOf(substring);if(index2===-1){return string}const substringLength=substring.length;let endIndex=0;let returnValue="";do{returnValue+=string.substr(endIndex,index2-endIndex)+substring+replacer;endIndex=index2+substringLength;index2=string.indexOf(substring,endIndex)}while(index2!==-1);returnValue+=string.substr(endIndex);return returnValue},"stringReplaceAll$1");const stringEncaseCRLFWithFirstIndex$1=__name((string,prefix,postfix,index2)=>{let endIndex=0;let returnValue="";do{const gotCR=string[index2-1]==="\r";returnValue+=string.substr(endIndex,(gotCR?index2-1:index2)-endIndex)+prefix+(gotCR?"\r\n":"\n")+postfix;endIndex=index2+1;index2=string.indexOf("\n",endIndex)}while(index2!==-1);returnValue+=string.substr(endIndex);return returnValue},"stringEncaseCRLFWithFirstIndex$1");var util={stringReplaceAll:stringReplaceAll$1,stringEncaseCRLFWithFirstIndex:stringEncaseCRLFWithFirstIndex$1};var templates;var hasRequiredTemplates;function requireTemplates(){if(hasRequiredTemplates)return templates;hasRequiredTemplates=1;const TEMPLATE_REGEX=/(?:\\(u(?:[a-f\d]{4}|\{[a-f\d]{1,6}\})|x[a-f\d]{2}|.))|(?:\{(~)?(\w+(?:\([^)]*\))?(?:\.\w+(?:\([^)]*\))?)*)(?:[ \t]|(?=\r?\n)))|(\})|((?:.|[\r\n\f])+?)/gi;const STYLE_REGEX=/(?:^|\.)(\w+)(?:\(([^)]*)\))?/g;const STRING_REGEX=/^(['"])((?:\\.|(?!\1)[^\\])*)\1$/;const ESCAPE_REGEX=/\\(u(?:[a-f\d]{4}|{[a-f\d]{1,6}})|x[a-f\d]{2}|.)|([^\\])/gi;const ESCAPES=new Map([["n","\n"],["r","\r"],["t","	"],["b","\b"],["f","\f"],["v","\v"],["0","\0"],["\\","\\"],["e","\x1B"],["a","\x07"]]);function unescape(c){const u=c[0]==="u";const bracket=c[1]==="{";if(u&&!bracket&&c.length===5||c[0]==="x"&&c.length===3){return String.fromCharCode(parseInt(c.slice(1),16))}if(u&&bracket){return String.fromCodePoint(parseInt(c.slice(2,-1),16))}return ESCAPES.get(c)||c}__name(unescape,"unescape");function parseArguments(name,arguments_){const results=[];const chunks=arguments_.trim().split(/\s*,\s*/g);let matches;for(const chunk of chunks){const number=Number(chunk);if(!Number.isNaN(number)){results.push(number)}else if(matches=chunk.match(STRING_REGEX)){results.push(matches[2].replace(ESCAPE_REGEX,(m,escape,character)=>escape?unescape(escape):character))}else{throw new Error(`Invalid Chalk template style argument: ${chunk} (in style '${name}')`)}}return results}__name(parseArguments,"parseArguments");function parseStyle(style){STYLE_REGEX.lastIndex=0;const results=[];let matches;while((matches=STYLE_REGEX.exec(style))!==null){const name=matches[1];if(matches[2]){const args=parseArguments(name,matches[2]);results.push([name].concat(args))}else{results.push([name])}}return results}__name(parseStyle,"parseStyle");function buildStyle(chalk2,styles2){const enabled={};for(const layer of styles2){for(const style of layer.styles){enabled[style[0]]=layer.inverse?null:style.slice(1)}}let current=chalk2;for(const[styleName,styles3]of Object.entries(enabled)){if(!Array.isArray(styles3)){continue}if(!(styleName in current)){throw new Error(`Unknown Chalk style: ${styleName}`)}current=styles3.length>0?current[styleName](...styles3):current[styleName]}return current}__name(buildStyle,"buildStyle");templates=__name((chalk2,temporary)=>{const styles2=[];const chunks=[];let chunk=[];temporary.replace(TEMPLATE_REGEX,(m,escapeCharacter,inverse,style,close,character)=>{if(escapeCharacter){chunk.push(unescape(escapeCharacter))}else if(style){const string=chunk.join("");chunk=[];chunks.push(styles2.length===0?string:buildStyle(chalk2,styles2)(string));styles2.push({inverse,styles:parseStyle(style)})}else if(close){if(styles2.length===0){throw new Error("Found extraneous } in Chalk template literal")}chunks.push(buildStyle(chalk2,styles2)(chunk.join("")));chunk=[];styles2.pop()}else{chunk.push(character)}});chunks.push(chunk.join(""));if(styles2.length>0){const errMessage=`Chalk template literal is missing ${styles2.length} closing bracket${styles2.length===1?"":"s"} (\`}\`)`;throw new Error(errMessage)}return chunks.join("")},"templates");return templates}__name(requireTemplates,"requireTemplates");const ansiStyles=ansiStylesExports;const{stdout:stdoutColor,stderr:stderrColor}=browser;const{stringReplaceAll,stringEncaseCRLFWithFirstIndex}=util;const{isArray:isArray$4}=Array;const levelMapping=["ansi","ansi","ansi256","ansi16m"];const styles=Object.create(null);const applyOptions=__name((object,options={})=>{if(options.level&&!(Number.isInteger(options.level)&&options.level>=0&&options.level<=3)){throw new Error("The `level` option should be an integer from 0 to 3")}const colorLevel=stdoutColor?stdoutColor.level:0;object.level=options.level===void 0?colorLevel:options.level},"applyOptions");class ChalkClass{constructor(options){return chalkFactory(options)}}__name(ChalkClass,"ChalkClass");const chalkFactory=__name(options=>{const chalk2={};applyOptions(chalk2,options);chalk2.template=(...arguments_)=>chalkTag(chalk2.template,...arguments_);Object.setPrototypeOf(chalk2,Chalk.prototype);Object.setPrototypeOf(chalk2.template,chalk2);chalk2.template.constructor=()=>{throw new Error("`chalk.constructor()` is deprecated. Use `new chalk.Instance()` instead.")};chalk2.template.Instance=ChalkClass;return chalk2.template},"chalkFactory");function Chalk(options){return chalkFactory(options)}__name(Chalk,"Chalk");for(const[styleName,style]of Object.entries(ansiStyles)){styles[styleName]={get(){const builder=createBuilder(this,createStyler(style.open,style.close,this._styler),this._isEmpty);Object.defineProperty(this,styleName,{value:builder});return builder}}}styles.visible={get(){const builder=createBuilder(this,this._styler,true);Object.defineProperty(this,"visible",{value:builder});return builder}};const usedModels=["rgb","hex","keyword","hsl","hsv","hwb","ansi","ansi256"];for(const model of usedModels){styles[model]={get(){const{level}=this;return function(...arguments_){const styler=createStyler(ansiStyles.color[levelMapping[level]][model](...arguments_),ansiStyles.color.close,this._styler);return createBuilder(this,styler,this._isEmpty)}}}}for(const model of usedModels){const bgModel="bg"+model[0].toUpperCase()+model.slice(1);styles[bgModel]={get(){const{level}=this;return function(...arguments_){const styler=createStyler(ansiStyles.bgColor[levelMapping[level]][model](...arguments_),ansiStyles.bgColor.close,this._styler);return createBuilder(this,styler,this._isEmpty)}}}}const proto=Object.defineProperties(()=>{},__spreadProps(__spreadValues({},styles),{level:{enumerable:true,get(){return this._generator.level},set(level){this._generator.level=level}}}));const createStyler=__name((open,close,parent)=>{let openAll;let closeAll;if(parent===void 0){openAll=open;closeAll=close}else{openAll=parent.openAll+open;closeAll=close+parent.closeAll}return{open,close,openAll,closeAll,parent}},"createStyler");const createBuilder=__name((self2,_styler,_isEmpty)=>{const builder=__name((...arguments_)=>{if(isArray$4(arguments_[0])&&isArray$4(arguments_[0].raw)){return applyStyle(builder,chalkTag(builder,...arguments_))}return applyStyle(builder,arguments_.length===1?""+arguments_[0]:arguments_.join(" "))},"builder");Object.setPrototypeOf(builder,proto);builder._generator=self2;builder._styler=_styler;builder._isEmpty=_isEmpty;return builder},"createBuilder");const applyStyle=__name((self2,string)=>{if(self2.level<=0||!string){return self2._isEmpty?"":string}let styler=self2._styler;if(styler===void 0){return string}const{openAll,closeAll}=styler;if(string.indexOf("\x1B")!==-1){while(styler!==void 0){string=stringReplaceAll(string,styler.close,styler.open);styler=styler.parent}}const lfIndex=string.indexOf("\n");if(lfIndex!==-1){string=stringEncaseCRLFWithFirstIndex(string,closeAll,openAll,lfIndex)}return openAll+string+closeAll},"applyStyle");let template;const chalkTag=__name((chalk2,...strings)=>{const[firstString]=strings;if(!isArray$4(firstString)||!isArray$4(firstString.raw)){return strings.join(" ")}const arguments_=strings.slice(1);const parts=[firstString.raw[0]];for(let i=1;i<firstString.length;i++){parts.push(String(arguments_[i-1]).replace(/[{}\\]/g,"\\$&"),String(firstString.raw[i]))}if(template===void 0){template=requireTemplates()}return template(chalk2,parts.join(""))},"chalkTag");Object.defineProperties(Chalk.prototype,styles);const chalk=Chalk();chalk.supportsColor=stdoutColor;chalk.stderr=Chalk({level:stderrColor?stderrColor.level:0});chalk.stderr.supportsColor=stderrColor;var source=chalk;const chalk$1=getDefaultExportFromCjs(source);var _typeof=typeof Symbol==="function"&&typeof Symbol.iterator==="symbol"?function(obj){return typeof obj}:function(obj){return obj&&typeof Symbol==="function"&&obj.constructor===Symbol&&obj!==Symbol.prototype?"symbol":typeof obj};var classCallCheck=__name(function(instance,Constructor){if(!(instance instanceof Constructor)){throw new TypeError("Cannot call a class as a function")}},"classCallCheck");var createClass=function(){function defineProperties(target,props){for(var i=0;i<props.length;i++){var descriptor=props[i];descriptor.enumerable=descriptor.enumerable||false;descriptor.configurable=true;if("value"in descriptor)descriptor.writable=true;Object.defineProperty(target,descriptor.key,descriptor)}}__name(defineProperties,"defineProperties");return function(Constructor,protoProps,staticProps){if(protoProps)defineProperties(Constructor.prototype,protoProps);if(staticProps)defineProperties(Constructor,staticProps);return Constructor}}();var get=__name(function get2(object,property,receiver){if(object===null)object=Function.prototype;var desc=Object.getOwnPropertyDescriptor(object,property);if(desc===void 0){var parent=Object.getPrototypeOf(object);if(parent===null){return void 0}else{return get2(parent,property,receiver)}}else if("value"in desc){return desc.value}else{var getter=desc.get;if(getter===void 0){return void 0}return getter.call(receiver)}},"get");var inherits=__name(function(subClass,superClass){if(typeof superClass!=="function"&&superClass!==null){throw new TypeError("Super expression must either be null or a function, not "+typeof superClass)}subClass.prototype=Object.create(superClass&&superClass.prototype,{constructor:{value:subClass,enumerable:false,writable:true,configurable:true}});if(superClass)Object.setPrototypeOf?Object.setPrototypeOf(subClass,superClass):subClass.__proto__=superClass},"inherits");var possibleConstructorReturn=__name(function(self2,call){if(!self2){throw new ReferenceError("this hasn't been initialised - super() hasn't been called")}return call&&(typeof call==="object"||typeof call==="function")?call:self2},"possibleConstructorReturn");var Processor=function(){function Processor2(options){classCallCheck(this,Processor2);this.selfOptions=options||{};this.pipes={}}__name(Processor2,"Processor");createClass(Processor2,[{key:"options",value:__name(function options(_options){if(_options){this.selfOptions=_options}return this.selfOptions},"options")},{key:"pipe",value:__name(function pipe(name,pipeArg){var pipe2=pipeArg;if(typeof name==="string"){if(typeof pipe2==="undefined"){return this.pipes[name]}else{this.pipes[name]=pipe2}}if(name&&name.name){pipe2=name;if(pipe2.processor===this){return pipe2}this.pipes[pipe2.name]=pipe2}pipe2.processor=this;return pipe2},"pipe")},{key:"process",value:__name(function process2(input,pipe){var context=input;context.options=this.options();var nextPipe=pipe||input.pipe||"default";var lastPipe=void 0;var lastContext=void 0;while(nextPipe){if(typeof context.nextAfterChildren!=="undefined"){context.next=context.nextAfterChildren;context.nextAfterChildren=null}if(typeof nextPipe==="string"){nextPipe=this.pipe(nextPipe)}nextPipe.process(context);lastContext=context;lastPipe=nextPipe;nextPipe=null;if(context){if(context.next){context=context.next;nextPipe=lastContext.nextPipe||context.pipe||lastPipe}}}return context.hasResult?context.result:void 0},"process")}]);return Processor2}();var Pipe=function(){function Pipe2(name){classCallCheck(this,Pipe2);this.name=name;this.filters=[]}__name(Pipe2,"Pipe");createClass(Pipe2,[{key:"process",value:__name(function process2(input){if(!this.processor){throw new Error("add this pipe to a processor before using it")}var debug=this.debug;var length=this.filters.length;var context=input;for(var index2=0;index2<length;index2++){var filter=this.filters[index2];if(debug){this.log("filter: "+filter.filterName)}filter(context);if((typeof context==="undefined"?"undefined":_typeof(context))==="object"&&context.exiting){context.exiting=false;break}}if(!context.next&&this.resultCheck){this.resultCheck(context)}},"process")},{key:"log",value:__name(function log(msg){console.log("[jsondiffpatch] "+this.name+" pipe, "+msg)},"log")},{key:"append",value:__name(function append(){var _filters;(_filters=this.filters).push.apply(_filters,arguments);return this},"append")},{key:"prepend",value:__name(function prepend(){var _filters2;(_filters2=this.filters).unshift.apply(_filters2,arguments);return this},"prepend")},{key:"indexOf",value:__name(function indexOf(filterName){if(!filterName){throw new Error("a filter name is required")}for(var index2=0;index2<this.filters.length;index2++){var filter=this.filters[index2];if(filter.filterName===filterName){return index2}}throw new Error("filter not found: "+filterName)},"indexOf")},{key:"list",value:__name(function list(){return this.filters.map(function(f){return f.filterName})},"list")},{key:"after",value:__name(function after(filterName){var index2=this.indexOf(filterName);var params=Array.prototype.slice.call(arguments,1);if(!params.length){throw new Error("a filter is required")}params.unshift(index2+1,0);Array.prototype.splice.apply(this.filters,params);return this},"after")},{key:"before",value:__name(function before(filterName){var index2=this.indexOf(filterName);var params=Array.prototype.slice.call(arguments,1);if(!params.length){throw new Error("a filter is required")}params.unshift(index2,0);Array.prototype.splice.apply(this.filters,params);return this},"before")},{key:"replace",value:__name(function replace(filterName){var index2=this.indexOf(filterName);var params=Array.prototype.slice.call(arguments,1);if(!params.length){throw new Error("a filter is required")}params.unshift(index2,1);Array.prototype.splice.apply(this.filters,params);return this},"replace")},{key:"remove",value:__name(function remove(filterName){var index2=this.indexOf(filterName);this.filters.splice(index2,1);return this},"remove")},{key:"clear",value:__name(function clear(){this.filters.length=0;return this},"clear")},{key:"shouldHaveResult",value:__name(function shouldHaveResult(should){if(should===false){this.resultCheck=null;return}if(this.resultCheck){return}var pipe=this;this.resultCheck=function(context){if(!context.hasResult){console.log(context);var error=new Error(pipe.name+" failed");error.noResult=true;throw error}};return this},"shouldHaveResult")}]);return Pipe2}();var Context=function(){function Context2(){classCallCheck(this,Context2)}__name(Context2,"Context");createClass(Context2,[{key:"setResult",value:__name(function setResult(result){this.result=result;this.hasResult=true;return this},"setResult")},{key:"exit",value:__name(function exit(){this.exiting=true;return this},"exit")},{key:"switchTo",value:__name(function switchTo(next2,pipe){if(typeof next2==="string"||next2 instanceof Pipe){this.nextPipe=next2}else{this.next=next2;if(pipe){this.nextPipe=pipe}}return this},"switchTo")},{key:"push",value:__name(function push(child,name){child.parent=this;if(typeof name!=="undefined"){child.childName=name}child.root=this.root||this;child.options=child.options||this.options;if(!this.children){this.children=[child];this.nextAfterChildren=this.next||null;this.next=child}else{this.children[this.children.length-1].next=child;this.children.push(child)}child.next=this;return this},"push")}]);return Context2}();var isArray=typeof Array.isArray==="function"?Array.isArray:function(a){return a instanceof Array};function cloneRegExp(re){var regexMatch=/^\/(.*)\/([gimyu]*)$/.exec(re.toString());return new RegExp(regexMatch[1],regexMatch[2])}__name(cloneRegExp,"cloneRegExp");function clone(arg){if((typeof arg==="undefined"?"undefined":_typeof(arg))!=="object"){return arg}if(arg===null){return null}if(isArray(arg)){return arg.map(clone)}if(arg instanceof Date){return new Date(arg.getTime())}if(arg instanceof RegExp){return cloneRegExp(arg)}var cloned={};for(var name in arg){if(Object.prototype.hasOwnProperty.call(arg,name)){cloned[name]=clone(arg[name])}}return cloned}__name(clone,"clone");var DiffContext=function(_Context){inherits(DiffContext2,_Context);function DiffContext2(left,right){classCallCheck(this,DiffContext2);var _this=possibleConstructorReturn(this,(DiffContext2.__proto__||Object.getPrototypeOf(DiffContext2)).call(this));_this.left=left;_this.right=right;_this.pipe="diff";return _this}__name(DiffContext2,"DiffContext");createClass(DiffContext2,[{key:"setResult",value:__name(function setResult(result){if(this.options.cloneDiffValues&&(typeof result==="undefined"?"undefined":_typeof(result))==="object"){var clone$$1=typeof this.options.cloneDiffValues==="function"?this.options.cloneDiffValues:clone;if(_typeof(result[0])==="object"){result[0]=clone$$1(result[0])}if(_typeof(result[1])==="object"){result[1]=clone$$1(result[1])}}return Context.prototype.setResult.apply(this,arguments)},"setResult")}]);return DiffContext2}(Context);var PatchContext=function(_Context){inherits(PatchContext2,_Context);function PatchContext2(left,delta){classCallCheck(this,PatchContext2);var _this=possibleConstructorReturn(this,(PatchContext2.__proto__||Object.getPrototypeOf(PatchContext2)).call(this));_this.left=left;_this.delta=delta;_this.pipe="patch";return _this}__name(PatchContext2,"PatchContext");return PatchContext2}(Context);var ReverseContext=function(_Context){inherits(ReverseContext2,_Context);function ReverseContext2(delta){classCallCheck(this,ReverseContext2);var _this=possibleConstructorReturn(this,(ReverseContext2.__proto__||Object.getPrototypeOf(ReverseContext2)).call(this));_this.delta=delta;_this.pipe="reverse";return _this}__name(ReverseContext2,"ReverseContext");return ReverseContext2}(Context);var isArray$1=typeof Array.isArray==="function"?Array.isArray:function(a){return a instanceof Array};var diffFilter=__name(function trivialMatchesDiffFilter(context){if(context.left===context.right){context.setResult(void 0).exit();return}if(typeof context.left==="undefined"){if(typeof context.right==="function"){throw new Error("functions are not supported")}context.setResult([context.right]).exit();return}if(typeof context.right==="undefined"){context.setResult([context.left,0,0]).exit();return}if(typeof context.left==="function"||typeof context.right==="function"){throw new Error("functions are not supported")}context.leftType=context.left===null?"null":_typeof(context.left);context.rightType=context.right===null?"null":_typeof(context.right);if(context.leftType!==context.rightType){context.setResult([context.left,context.right]).exit();return}if(context.leftType==="boolean"||context.leftType==="number"){context.setResult([context.left,context.right]).exit();return}if(context.leftType==="object"){context.leftIsArray=isArray$1(context.left)}if(context.rightType==="object"){context.rightIsArray=isArray$1(context.right)}if(context.leftIsArray!==context.rightIsArray){context.setResult([context.left,context.right]).exit();return}if(context.left instanceof RegExp){if(context.right instanceof RegExp){context.setResult([context.left.toString(),context.right.toString()]).exit()}else{context.setResult([context.left,context.right]).exit()}}},"trivialMatchesDiffFilter");diffFilter.filterName="trivial";var patchFilter=__name(function trivialMatchesPatchFilter(context){if(typeof context.delta==="undefined"){context.setResult(context.left).exit();return}context.nested=!isArray$1(context.delta);if(context.nested){return}if(context.delta.length===1){context.setResult(context.delta[0]).exit();return}if(context.delta.length===2){if(context.left instanceof RegExp){var regexArgs=/^\/(.*)\/([gimyu]+)$/.exec(context.delta[1]);if(regexArgs){context.setResult(new RegExp(regexArgs[1],regexArgs[2])).exit();return}}context.setResult(context.delta[1]).exit();return}if(context.delta.length===3&&context.delta[2]===0){context.setResult(void 0).exit()}},"trivialMatchesPatchFilter");patchFilter.filterName="trivial";var reverseFilter=__name(function trivialReferseFilter(context){if(typeof context.delta==="undefined"){context.setResult(context.delta).exit();return}context.nested=!isArray$1(context.delta);if(context.nested){return}if(context.delta.length===1){context.setResult([context.delta[0],0,0]).exit();return}if(context.delta.length===2){context.setResult([context.delta[1],context.delta[0]]).exit();return}if(context.delta.length===3&&context.delta[2]===0){context.setResult([context.delta[0]]).exit()}},"trivialReferseFilter");reverseFilter.filterName="trivial";function collectChildrenDiffFilter(context){if(!context||!context.children){return}var length=context.children.length;var child=void 0;var result=context.result;for(var index2=0;index2<length;index2++){child=context.children[index2];if(typeof child.result==="undefined"){continue}result=result||{};result[child.childName]=child.result}if(result&&context.leftIsArray){result._t="a"}context.setResult(result).exit()}__name(collectChildrenDiffFilter,"collectChildrenDiffFilter");collectChildrenDiffFilter.filterName="collectChildren";function objectsDiffFilter(context){if(context.leftIsArray||context.leftType!=="object"){return}var name=void 0;var child=void 0;var propertyFilter=context.options.propertyFilter;for(name in context.left){if(!Object.prototype.hasOwnProperty.call(context.left,name)){continue}if(propertyFilter&&!propertyFilter(name,context)){continue}child=new DiffContext(context.left[name],context.right[name]);context.push(child,name)}for(name in context.right){if(!Object.prototype.hasOwnProperty.call(context.right,name)){continue}if(propertyFilter&&!propertyFilter(name,context)){continue}if(typeof context.left[name]==="undefined"){child=new DiffContext(void 0,context.right[name]);context.push(child,name)}}if(!context.children||context.children.length===0){context.setResult(void 0).exit();return}context.exit()}__name(objectsDiffFilter,"objectsDiffFilter");objectsDiffFilter.filterName="objects";var patchFilter$1=__name(function nestedPatchFilter(context){if(!context.nested){return}if(context.delta._t){return}var name=void 0;var child=void 0;for(name in context.delta){child=new PatchContext(context.left[name],context.delta[name]);context.push(child,name)}context.exit()},"nestedPatchFilter");patchFilter$1.filterName="objects";var collectChildrenPatchFilter=__name(function collectChildrenPatchFilter2(context){if(!context||!context.children){return}if(context.delta._t){return}var length=context.children.length;var child=void 0;for(var index2=0;index2<length;index2++){child=context.children[index2];if(Object.prototype.hasOwnProperty.call(context.left,child.childName)&&child.result===void 0){delete context.left[child.childName]}else if(context.left[child.childName]!==child.result){context.left[child.childName]=child.result}}context.setResult(context.left).exit()},"collectChildrenPatchFilter");collectChildrenPatchFilter.filterName="collectChildren";var reverseFilter$1=__name(function nestedReverseFilter(context){if(!context.nested){return}if(context.delta._t){return}var name=void 0;var child=void 0;for(name in context.delta){child=new ReverseContext(context.delta[name]);context.push(child,name)}context.exit()},"nestedReverseFilter");reverseFilter$1.filterName="objects";function collectChildrenReverseFilter(context){if(!context||!context.children){return}if(context.delta._t){return}var length=context.children.length;var child=void 0;var delta={};for(var index2=0;index2<length;index2++){child=context.children[index2];if(delta[child.childName]!==child.result){delta[child.childName]=child.result}}context.setResult(delta).exit()}__name(collectChildrenReverseFilter,"collectChildrenReverseFilter");collectChildrenReverseFilter.filterName="collectChildren";var defaultMatch=__name(function defaultMatch2(array1,array2,index1,index2){return array1[index1]===array2[index2]},"defaultMatch");var lengthMatrix=__name(function lengthMatrix2(array1,array2,match,context){var len1=array1.length;var len2=array2.length;var x=void 0,y=void 0;var matrix=[len1+1];for(x=0;x<len1+1;x++){matrix[x]=[len2+1];for(y=0;y<len2+1;y++){matrix[x][y]=0}}matrix.match=match;for(x=1;x<len1+1;x++){for(y=1;y<len2+1;y++){if(match(array1,array2,x-1,y-1,context)){matrix[x][y]=matrix[x-1][y-1]+1}else{matrix[x][y]=Math.max(matrix[x-1][y],matrix[x][y-1])}}}return matrix},"lengthMatrix");var backtrack=__name(function backtrack2(matrix,array1,array2,context){var index1=array1.length;var index2=array2.length;var subsequence={sequence:[],indices1:[],indices2:[]};while(index1!==0&&index2!==0){var sameLetter=matrix.match(array1,array2,index1-1,index2-1,context);if(sameLetter){subsequence.sequence.unshift(array1[index1-1]);subsequence.indices1.unshift(index1-1);subsequence.indices2.unshift(index2-1);--index1;--index2}else{var valueAtMatrixAbove=matrix[index1][index2-1];var valueAtMatrixLeft=matrix[index1-1][index2];if(valueAtMatrixAbove>valueAtMatrixLeft){--index2}else{--index1}}}return subsequence},"backtrack");var get$1=__name(function get3(array1,array2,match,context){var innerContext=context||{};var matrix=lengthMatrix(array1,array2,match||defaultMatch,innerContext);var result=backtrack(matrix,array1,array2,innerContext);if(typeof array1==="string"&&typeof array2==="string"){result.sequence=result.sequence.join("")}return result},"get");var lcs={get:get$1};var ARRAY_MOVE=3;var isArray$2=typeof Array.isArray==="function"?Array.isArray:function(a){return a instanceof Array};var arrayIndexOf=typeof Array.prototype.indexOf==="function"?function(array,item){return array.indexOf(item)}:function(array,item){var length=array.length;for(var i=0;i<length;i++){if(array[i]===item){return i}}return-1};function arraysHaveMatchByRef(array1,array2,len1,len2){for(var index1=0;index1<len1;index1++){var val1=array1[index1];for(var index2=0;index2<len2;index2++){var val2=array2[index2];if(index1!==index2&&val1===val2){return true}}}}__name(arraysHaveMatchByRef,"arraysHaveMatchByRef");function matchItems(array1,array2,index1,index2,context){var value1=array1[index1];var value2=array2[index2];if(value1===value2){return true}if((typeof value1==="undefined"?"undefined":_typeof(value1))!=="object"||(typeof value2==="undefined"?"undefined":_typeof(value2))!=="object"){return false}var objectHash=context.objectHash;if(!objectHash){return context.matchByPosition&&index1===index2}var hash1=void 0;var hash2=void 0;if(typeof index1==="number"){context.hashCache1=context.hashCache1||[];hash1=context.hashCache1[index1];if(typeof hash1==="undefined"){context.hashCache1[index1]=hash1=objectHash(value1,index1)}}else{hash1=objectHash(value1)}if(typeof hash1==="undefined"){return false}if(typeof index2==="number"){context.hashCache2=context.hashCache2||[];hash2=context.hashCache2[index2];if(typeof hash2==="undefined"){context.hashCache2[index2]=hash2=objectHash(value2,index2)}}else{hash2=objectHash(value2)}if(typeof hash2==="undefined"){return false}return hash1===hash2}__name(matchItems,"matchItems");var diffFilter$1=__name(function arraysDiffFilter(context){if(!context.leftIsArray){return}var matchContext={objectHash:context.options&&context.options.objectHash,matchByPosition:context.options&&context.options.matchByPosition};var commonHead=0;var commonTail=0;var index2=void 0;var index1=void 0;var index22=void 0;var array1=context.left;var array2=context.right;var len1=array1.length;var len2=array2.length;var child=void 0;if(len1>0&&len2>0&&!matchContext.objectHash&&typeof matchContext.matchByPosition!=="boolean"){matchContext.matchByPosition=!arraysHaveMatchByRef(array1,array2,len1,len2)}while(commonHead<len1&&commonHead<len2&&matchItems(array1,array2,commonHead,commonHead,matchContext)){index2=commonHead;child=new DiffContext(context.left[index2],context.right[index2]);context.push(child,index2);commonHead++}while(commonTail+commonHead<len1&&commonTail+commonHead<len2&&matchItems(array1,array2,len1-1-commonTail,len2-1-commonTail,matchContext)){index1=len1-1-commonTail;index22=len2-1-commonTail;child=new DiffContext(context.left[index1],context.right[index22]);context.push(child,index22);commonTail++}var result=void 0;if(commonHead+commonTail===len1){if(len1===len2){context.setResult(void 0).exit();return}result=result||{_t:"a"};for(index2=commonHead;index2<len2-commonTail;index2++){result[index2]=[array2[index2]]}context.setResult(result).exit();return}if(commonHead+commonTail===len2){result=result||{_t:"a"};for(index2=commonHead;index2<len1-commonTail;index2++){result["_"+index2]=[array1[index2],0,0]}context.setResult(result).exit();return}delete matchContext.hashCache1;delete matchContext.hashCache2;var trimmed1=array1.slice(commonHead,len1-commonTail);var trimmed2=array2.slice(commonHead,len2-commonTail);var seq=lcs.get(trimmed1,trimmed2,matchItems,matchContext);var removedItems=[];result=result||{_t:"a"};for(index2=commonHead;index2<len1-commonTail;index2++){if(arrayIndexOf(seq.indices1,index2-commonHead)<0){result["_"+index2]=[array1[index2],0,0];removedItems.push(index2)}}var detectMove=true;if(context.options&&context.options.arrays&&context.options.arrays.detectMove===false){detectMove=false}var includeValueOnMove=false;if(context.options&&context.options.arrays&&context.options.arrays.includeValueOnMove){includeValueOnMove=true}var removedItemsLength=removedItems.length;for(index2=commonHead;index2<len2-commonTail;index2++){var indexOnArray2=arrayIndexOf(seq.indices2,index2-commonHead);if(indexOnArray2<0){var isMove=false;if(detectMove&&removedItemsLength>0){for(var removeItemIndex1=0;removeItemIndex1<removedItemsLength;removeItemIndex1++){index1=removedItems[removeItemIndex1];if(matchItems(trimmed1,trimmed2,index1-commonHead,index2-commonHead,matchContext)){result["_"+index1].splice(1,2,index2,ARRAY_MOVE);if(!includeValueOnMove){result["_"+index1][0]=""}index22=index2;child=new DiffContext(context.left[index1],context.right[index22]);context.push(child,index22);removedItems.splice(removeItemIndex1,1);isMove=true;break}}}if(!isMove){result[index2]=[array2[index2]]}}else{index1=seq.indices1[indexOnArray2]+commonHead;index22=seq.indices2[indexOnArray2]+commonHead;child=new DiffContext(context.left[index1],context.right[index22]);context.push(child,index22)}}context.setResult(result).exit()},"arraysDiffFilter");diffFilter$1.filterName="arrays";var compare={numerically:__name(function numerically(a,b){return a-b},"numerically"),numericallyBy:__name(function numericallyBy(name){return function(a,b){return a[name]-b[name]}},"numericallyBy")};var patchFilter$2=__name(function nestedPatchFilter2(context){if(!context.nested){return}if(context.delta._t!=="a"){return}var index2=void 0;var index1=void 0;var delta=context.delta;var array=context.left;var toRemove=[];var toInsert=[];var toModify=[];for(index2 in delta){if(index2!=="_t"){if(index2[0]==="_"){if(delta[index2][2]===0||delta[index2][2]===ARRAY_MOVE){toRemove.push(parseInt(index2.slice(1),10))}else{throw new Error("only removal or move can be applied at original array indices,"+(" invalid diff type: "+delta[index2][2]))}}else{if(delta[index2].length===1){toInsert.push({index:parseInt(index2,10),value:delta[index2][0]})}else{toModify.push({index:parseInt(index2,10),delta:delta[index2]})}}}}toRemove=toRemove.sort(compare.numerically);for(index2=toRemove.length-1;index2>=0;index2--){index1=toRemove[index2];var indexDiff=delta["_"+index1];var removedValue=array.splice(index1,1)[0];if(indexDiff[2]===ARRAY_MOVE){toInsert.push({index:indexDiff[1],value:removedValue})}}toInsert=toInsert.sort(compare.numericallyBy("index"));var toInsertLength=toInsert.length;for(index2=0;index2<toInsertLength;index2++){var insertion=toInsert[index2];array.splice(insertion.index,0,insertion.value)}var toModifyLength=toModify.length;var child=void 0;if(toModifyLength>0){for(index2=0;index2<toModifyLength;index2++){var modification=toModify[index2];child=new PatchContext(context.left[modification.index],modification.delta);context.push(child,modification.index)}}if(!context.children){context.setResult(context.left).exit();return}context.exit()},"nestedPatchFilter");patchFilter$2.filterName="arrays";var collectChildrenPatchFilter$1=__name(function collectChildrenPatchFilter3(context){if(!context||!context.children){return}if(context.delta._t!=="a"){return}var length=context.children.length;var child=void 0;for(var index2=0;index2<length;index2++){child=context.children[index2];context.left[child.childName]=child.result}context.setResult(context.left).exit()},"collectChildrenPatchFilter");collectChildrenPatchFilter$1.filterName="arraysCollectChildren";var reverseFilter$2=__name(function arraysReverseFilter(context){if(!context.nested){if(context.delta[2]===ARRAY_MOVE){context.newName="_"+context.delta[1];context.setResult([context.delta[0],parseInt(context.childName.substr(1),10),ARRAY_MOVE]).exit()}return}if(context.delta._t!=="a"){return}var name=void 0;var child=void 0;for(name in context.delta){if(name==="_t"){continue}child=new ReverseContext(context.delta[name]);context.push(child,name)}context.exit()},"arraysReverseFilter");reverseFilter$2.filterName="arrays";var reverseArrayDeltaIndex=__name(function reverseArrayDeltaIndex2(delta,index2,itemDelta){if(typeof index2==="string"&&index2[0]==="_"){return parseInt(index2.substr(1),10)}else if(isArray$2(itemDelta)&&itemDelta[2]===0){return"_"+index2}var reverseIndex=+index2;for(var deltaIndex in delta){var deltaItem=delta[deltaIndex];if(isArray$2(deltaItem)){if(deltaItem[2]===ARRAY_MOVE){var moveFromIndex=parseInt(deltaIndex.substr(1),10);var moveToIndex=deltaItem[1];if(moveToIndex===+index2){return moveFromIndex}if(moveFromIndex<=reverseIndex&&moveToIndex>reverseIndex){reverseIndex++}else if(moveFromIndex>=reverseIndex&&moveToIndex<reverseIndex){reverseIndex--}}else if(deltaItem[2]===0){var deleteIndex=parseInt(deltaIndex.substr(1),10);if(deleteIndex<=reverseIndex){reverseIndex++}}else if(deltaItem.length===1&&deltaIndex<=reverseIndex){reverseIndex--}}}return reverseIndex},"reverseArrayDeltaIndex");function collectChildrenReverseFilter$1(context){if(!context||!context.children){return}if(context.delta._t!=="a"){return}var length=context.children.length;var child=void 0;var delta={_t:"a"};for(var index2=0;index2<length;index2++){child=context.children[index2];var name=child.newName;if(typeof name==="undefined"){name=reverseArrayDeltaIndex(context.delta,child.childName,child.result)}if(delta[name]!==child.result){delta[name]=child.result}}context.setResult(delta).exit()}__name(collectChildrenReverseFilter$1,"collectChildrenReverseFilter$1");collectChildrenReverseFilter$1.filterName="arraysCollectChildren";var diffFilter$2=__name(function datesDiffFilter(context){if(context.left instanceof Date){if(context.right instanceof Date){if(context.left.getTime()!==context.right.getTime()){context.setResult([context.left,context.right])}else{context.setResult(void 0)}}else{context.setResult([context.left,context.right])}context.exit()}else if(context.right instanceof Date){context.setResult([context.left,context.right]).exit()}},"datesDiffFilter");diffFilter$2.filterName="dates";var TEXT_DIFF=2;var DEFAULT_MIN_LENGTH=60;var cachedDiffPatch=null;var getDiffMatchPatch=__name(function getDiffMatchPatch2(required){if(!cachedDiffPatch){var instance=void 0;if(typeof diff_match_patch!=="undefined"){instance=typeof diff_match_patch==="function"?new diff_match_patch:new diff_match_patch.diff_match_patch}else if(dmp){try{instance=dmp&&new dmp}catch(err){instance=null}}if(!instance){if(!required){return null}var error=new Error("text diff_match_patch library not found");error.diff_match_patch_not_found=true;throw error}cachedDiffPatch={diff:__name(function diff2(txt1,txt2){return instance.patch_toText(instance.patch_make(txt1,txt2))},"diff"),patch:__name(function patch2(txt1,_patch){var results=instance.patch_apply(instance.patch_fromText(_patch),txt1);for(var i=0;i<results[1].length;i++){if(!results[1][i]){var _error=new Error("text patch failed");_error.textPatchFailed=true}}return results[0]},"patch")}}return cachedDiffPatch},"getDiffMatchPatch");var diffFilter$3=__name(function textsDiffFilter(context){if(context.leftType!=="string"){return}var minLength=context.options&&context.options.textDiff&&context.options.textDiff.minLength||DEFAULT_MIN_LENGTH;if(context.left.length<minLength||context.right.length<minLength){context.setResult([context.left,context.right]).exit();return}var diffMatchPatch2=getDiffMatchPatch();if(!diffMatchPatch2){context.setResult([context.left,context.right]).exit();return}var diff2=diffMatchPatch2.diff;context.setResult([diff2(context.left,context.right),0,TEXT_DIFF]).exit()},"textsDiffFilter");diffFilter$3.filterName="texts";var patchFilter$3=__name(function textsPatchFilter(context){if(context.nested){return}if(context.delta[2]!==TEXT_DIFF){return}var patch2=getDiffMatchPatch(true).patch;context.setResult(patch2(context.left,context.delta[0])).exit()},"textsPatchFilter");patchFilter$3.filterName="texts";var textDeltaReverse=__name(function textDeltaReverse2(delta){var i=void 0;var l=void 0;var lines=void 0;var line=void 0;var lineTmp=void 0;var header=null;var headerRegex=/^@@ +-(\d+),(\d+) +\+(\d+),(\d+) +@@$/;var lineHeader=void 0;lines=delta.split("\n");for(i=0,l=lines.length;i<l;i++){line=lines[i];var lineStart=line.slice(0,1);if(lineStart==="@"){header=headerRegex.exec(line);lineHeader=i;lines[lineHeader]="@@ -"+header[3]+","+header[4]+" +"+header[1]+","+header[2]+" @@"}else if(lineStart==="+"){lines[i]="-"+lines[i].slice(1);if(lines[i-1].slice(0,1)==="+"){lineTmp=lines[i];lines[i]=lines[i-1];lines[i-1]=lineTmp}}else if(lineStart==="-"){lines[i]="+"+lines[i].slice(1)}}return lines.join("\n")},"textDeltaReverse");var reverseFilter$3=__name(function textsReverseFilter(context){if(context.nested){return}if(context.delta[2]!==TEXT_DIFF){return}context.setResult([textDeltaReverse(context.delta[0]),0,TEXT_DIFF]).exit()},"textsReverseFilter");reverseFilter$3.filterName="texts";var DiffPatcher=function(){function DiffPatcher2(options){classCallCheck(this,DiffPatcher2);this.processor=new Processor(options);this.processor.pipe(new Pipe("diff").append(collectChildrenDiffFilter,diffFilter,diffFilter$2,diffFilter$3,objectsDiffFilter,diffFilter$1).shouldHaveResult());this.processor.pipe(new Pipe("patch").append(collectChildrenPatchFilter,collectChildrenPatchFilter$1,patchFilter,patchFilter$3,patchFilter$1,patchFilter$2).shouldHaveResult());this.processor.pipe(new Pipe("reverse").append(collectChildrenReverseFilter,collectChildrenReverseFilter$1,reverseFilter,reverseFilter$3,reverseFilter$1,reverseFilter$2).shouldHaveResult())}__name(DiffPatcher2,"DiffPatcher");createClass(DiffPatcher2,[{key:"options",value:__name(function options(){var _processor;return(_processor=this.processor).options.apply(_processor,arguments)},"options")},{key:"diff",value:__name(function diff2(left,right){return this.processor.process(new DiffContext(left,right))},"diff")},{key:"patch",value:__name(function patch2(left,delta){return this.processor.process(new PatchContext(left,delta))},"patch")},{key:"reverse",value:__name(function reverse2(delta){return this.processor.process(new ReverseContext(delta))},"reverse")},{key:"unpatch",value:__name(function unpatch(right,delta){return this.patch(right,this.reverse(delta))},"unpatch")},{key:"clone",value:__name(function clone$$1(value){return clone(value)},"clone$$1")}]);return DiffPatcher2}();var isArray$3=typeof Array.isArray==="function"?Array.isArray:function(a){return a instanceof Array};var getObjectKeys=typeof Object.keys==="function"?function(obj){return Object.keys(obj)}:function(obj){var names=[];for(var property in obj){if(Object.prototype.hasOwnProperty.call(obj,property)){names.push(property)}}return names};var trimUnderscore=__name(function trimUnderscore2(str){if(str.substr(0,1)==="_"){return str.slice(1)}return str},"trimUnderscore");var arrayKeyToSortNumber=__name(function arrayKeyToSortNumber2(key){if(key==="_t"){return-1}else{if(key.substr(0,1)==="_"){return parseInt(key.slice(1),10)}else{return parseInt(key,10)+.1}}},"arrayKeyToSortNumber");var arrayKeyComparer=__name(function arrayKeyComparer2(key1,key2){return arrayKeyToSortNumber(key1)-arrayKeyToSortNumber(key2)},"arrayKeyComparer");var BaseFormatter=function(){function BaseFormatter2(){classCallCheck(this,BaseFormatter2)}__name(BaseFormatter2,"BaseFormatter");createClass(BaseFormatter2,[{key:"format",value:__name(function format(delta,left){var context={};this.prepareContext(context);this.recurse(context,delta,left);return this.finalize(context)},"format")},{key:"prepareContext",value:__name(function prepareContext(context){context.buffer=[];context.out=function(){var _buffer;(_buffer=this.buffer).push.apply(_buffer,arguments)}},"prepareContext")},{key:"typeFormattterNotFound",value:__name(function typeFormattterNotFound(context,deltaType){throw new Error("cannot format delta type: "+deltaType)},"typeFormattterNotFound")},{key:"typeFormattterErrorFormatter",value:__name(function typeFormattterErrorFormatter(context,err){return err.toString()},"typeFormattterErrorFormatter")},{key:"finalize",value:__name(function finalize(_ref){var buffer2=_ref.buffer;if(isArray$3(buffer2)){return buffer2.join("")}},"finalize")},{key:"recurse",value:__name(function recurse(context,delta,left,key,leftKey,movedFrom,isLast){var useMoveOriginHere=delta&&movedFrom;var leftValue=useMoveOriginHere?movedFrom.value:left;if(typeof delta==="undefined"&&typeof key==="undefined"){return void 0}var type=this.getDeltaType(delta,movedFrom);var nodeType=type==="node"?delta._t==="a"?"array":"object":"";if(typeof key!=="undefined"){this.nodeBegin(context,key,leftKey,type,nodeType,isLast)}else{this.rootBegin(context,type,nodeType)}var typeFormattter=void 0;try{typeFormattter=this["format_"+type]||this.typeFormattterNotFound(context,type);typeFormattter.call(this,context,delta,leftValue,key,leftKey,movedFrom)}catch(err){this.typeFormattterErrorFormatter(context,err,delta,leftValue,key,leftKey,movedFrom);if(typeof console!=="undefined"&&console.error){console.error(err.stack)}}if(typeof key!=="undefined"){this.nodeEnd(context,key,leftKey,type,nodeType,isLast)}else{this.rootEnd(context,type,nodeType)}},"recurse")},{key:"formatDeltaChildren",value:__name(function formatDeltaChildren(context,delta,left){var self2=this;this.forEachDeltaKey(delta,left,function(key,leftKey,movedFrom,isLast){self2.recurse(context,delta[key],left?left[leftKey]:void 0,key,leftKey,movedFrom,isLast)})},"formatDeltaChildren")},{key:"forEachDeltaKey",value:__name(function forEachDeltaKey(delta,left,fn){var keys=getObjectKeys(delta);var arrayKeys=delta._t==="a";var moveDestinations={};var name=void 0;if(typeof left!=="undefined"){for(name in left){if(Object.prototype.hasOwnProperty.call(left,name)){if(typeof delta[name]==="undefined"&&(!arrayKeys||typeof delta["_"+name]==="undefined")){keys.push(name)}}}}for(name in delta){if(Object.prototype.hasOwnProperty.call(delta,name)){var value=delta[name];if(isArray$3(value)&&value[2]===3){moveDestinations[value[1].toString()]={key:name,value:left&&left[parseInt(name.substr(1))]};if(this.includeMoveDestinations!==false){if(typeof left==="undefined"&&typeof delta[value[1]]==="undefined"){keys.push(value[1].toString())}}}}}if(arrayKeys){keys.sort(arrayKeyComparer)}else{keys.sort()}for(var index2=0,length=keys.length;index2<length;index2++){var key=keys[index2];if(arrayKeys&&key==="_t"){continue}var leftKey=arrayKeys?typeof key==="number"?key:parseInt(trimUnderscore(key),10):key;var isLast=index2===length-1;fn(key,leftKey,moveDestinations[leftKey],isLast)}},"forEachDeltaKey")},{key:"getDeltaType",value:__name(function getDeltaType(delta,movedFrom){if(typeof delta==="undefined"){if(typeof movedFrom!=="undefined"){return"movedestination"}return"unchanged"}if(isArray$3(delta)){if(delta.length===1){return"added"}if(delta.length===2){return"modified"}if(delta.length===3&&delta[2]===0){return"deleted"}if(delta.length===3&&delta[2]===2){return"textdiff"}if(delta.length===3&&delta[2]===3){return"moved"}}else if((typeof delta==="undefined"?"undefined":_typeof(delta))==="object"){return"node"}return"unknown"},"getDeltaType")},{key:"parseTextDiff",value:__name(function parseTextDiff(value){var output=[];var lines=value.split("\n@@ ");for(var i=0,l=lines.length;i<l;i++){var line=lines[i];var lineOutput={pieces:[]};var location=/^(?:@@ )?[-+]?(\d+),(\d+)/.exec(line).slice(1);lineOutput.location={line:location[0],chr:location[1]};var pieces=line.split("\n").slice(1);for(var pieceIndex=0,piecesLength=pieces.length;pieceIndex<piecesLength;pieceIndex++){var piece=pieces[pieceIndex];if(!piece.length){continue}var pieceOutput={type:"context"};if(piece.substr(0,1)==="+"){pieceOutput.type="added"}else if(piece.substr(0,1)==="-"){pieceOutput.type="deleted"}pieceOutput.text=piece.slice(1);lineOutput.pieces.push(pieceOutput)}output.push(lineOutput)}return output},"parseTextDiff")}]);return BaseFormatter2}();(function(_BaseFormatter){inherits(HtmlFormatter,_BaseFormatter);function HtmlFormatter(){classCallCheck(this,HtmlFormatter);return possibleConstructorReturn(this,(HtmlFormatter.__proto__||Object.getPrototypeOf(HtmlFormatter)).apply(this,arguments))}__name(HtmlFormatter,"HtmlFormatter");createClass(HtmlFormatter,[{key:"typeFormattterErrorFormatter",value:__name(function typeFormattterErrorFormatter(context,err){context.out('<pre class="jsondiffpatch-error">'+err+"</pre>")},"typeFormattterErrorFormatter")},{key:"formatValue",value:__name(function formatValue(context,value){context.out("<pre>"+htmlEscape(JSON.stringify(value,null,2))+"</pre>")},"formatValue")},{key:"formatTextDiffString",value:__name(function formatTextDiffString(context,value){var lines=this.parseTextDiff(value);context.out('<ul class="jsondiffpatch-textdiff">');for(var i=0,l=lines.length;i<l;i++){var line=lines[i];context.out('<li><div class="jsondiffpatch-textdiff-location">'+('<span class="jsondiffpatch-textdiff-line-number">'+line.location.line+'</span><span class="jsondiffpatch-textdiff-char">'+line.location.chr+'</span></div><div class="jsondiffpatch-textdiff-line">'));var pieces=line.pieces;for(var pieceIndex=0,piecesLength=pieces.length;pieceIndex<piecesLength;pieceIndex++){var piece=pieces[pieceIndex];context.out('<span class="jsondiffpatch-textdiff-'+piece.type+'">'+htmlEscape(decodeURI(piece.text))+"</span>")}context.out("</div></li>")}context.out("</ul>")},"formatTextDiffString")},{key:"rootBegin",value:__name(function rootBegin(context,type,nodeType){var nodeClass="jsondiffpatch-"+type+(nodeType?" jsondiffpatch-child-node-type-"+nodeType:"");context.out('<div class="jsondiffpatch-delta '+nodeClass+'">')},"rootBegin")},{key:"rootEnd",value:__name(function rootEnd(context){context.out("</div>"+(context.hasArrows?'<script type="text/javascript">setTimeout('+(adjustArrows.toString()+",10);<\/script>"):""))},"rootEnd")},{key:"nodeBegin",value:__name(function nodeBegin(context,key,leftKey,type,nodeType){var nodeClass="jsondiffpatch-"+type+(nodeType?" jsondiffpatch-child-node-type-"+nodeType:"");context.out('<li class="'+nodeClass+'" data-key="'+leftKey+'">'+('<div class="jsondiffpatch-property-name">'+leftKey+"</div>"))},"nodeBegin")},{key:"nodeEnd",value:__name(function nodeEnd(context){context.out("</li>")},"nodeEnd")},{key:"format_unchanged",value:__name(function format_unchanged(context,delta,left){if(typeof left==="undefined"){return}context.out('<div class="jsondiffpatch-value">');this.formatValue(context,left);context.out("</div>")},"format_unchanged")},{key:"format_movedestination",value:__name(function format_movedestination(context,delta,left){if(typeof left==="undefined"){return}context.out('<div class="jsondiffpatch-value">');this.formatValue(context,left);context.out("</div>")},"format_movedestination")},{key:"format_node",value:__name(function format_node(context,delta,left){var nodeType=delta._t==="a"?"array":"object";context.out('<ul class="jsondiffpatch-node jsondiffpatch-node-type-'+nodeType+'">');this.formatDeltaChildren(context,delta,left);context.out("</ul>")},"format_node")},{key:"format_added",value:__name(function format_added(context,delta){context.out('<div class="jsondiffpatch-value">');this.formatValue(context,delta[0]);context.out("</div>")},"format_added")},{key:"format_modified",value:__name(function format_modified(context,delta){context.out('<div class="jsondiffpatch-value jsondiffpatch-left-value">');this.formatValue(context,delta[0]);context.out('</div><div class="jsondiffpatch-value jsondiffpatch-right-value">');this.formatValue(context,delta[1]);context.out("</div>")},"format_modified")},{key:"format_deleted",value:__name(function format_deleted(context,delta){context.out('<div class="jsondiffpatch-value">');this.formatValue(context,delta[0]);context.out("</div>")},"format_deleted")},{key:"format_moved",value:__name(function format_moved(context,delta){context.out('<div class="jsondiffpatch-value">');this.formatValue(context,delta[0]);context.out('</div><div class="jsondiffpatch-moved-destination">'+delta[1]+"</div>");context.out('<div class="jsondiffpatch-arrow" style="position: relative; left: -34px;">\n          <svg width="30" height="60" style="position: absolute; display: none;">\n          <defs>\n              <marker id="markerArrow" markerWidth="8" markerHeight="8"\n                 refx="2" refy="4"\n                     orient="auto" markerUnits="userSpaceOnUse">\n                  <path d="M1,1 L1,7 L7,4 L1,1" style="fill: #339;" />\n              </marker>\n          </defs>\n          <path d="M30,0 Q-10,25 26,50"\n            style="stroke: #88f; stroke-width: 2px; fill: none; stroke-opacity: 0.5; marker-end: url(#markerArrow);"\n          ></path>\n          </svg>\n      </div>');context.hasArrows=true},"format_moved")},{key:"format_textdiff",value:__name(function format_textdiff(context,delta){context.out('<div class="jsondiffpatch-value">');this.formatTextDiffString(context,delta[0]);context.out("</div>")},"format_textdiff")}]);return HtmlFormatter})(BaseFormatter);function htmlEscape(text){var html=text;var replacements=[[/&/g,"&amp;"],[/</g,"&lt;"],[/>/g,"&gt;"],[/'/g,"&apos;"],[/"/g,"&quot;"]];for(var i=0;i<replacements.length;i++){html=html.replace(replacements[i][0],replacements[i][1])}return html}__name(htmlEscape,"htmlEscape");var adjustArrows=__name(function jsondiffpatchHtmlFormatterAdjustArrows(nodeArg){var node=nodeArg||document;var getElementText=__name(function getElementText2(_ref){var textContent=_ref.textContent,innerText=_ref.innerText;return textContent||innerText},"getElementText");var eachByQuery=__name(function eachByQuery2(el,query,fn){var elems=el.querySelectorAll(query);for(var i=0,l=elems.length;i<l;i++){fn(elems[i])}},"eachByQuery");var eachChildren=__name(function eachChildren2(_ref2,fn){var children=_ref2.children;for(var i=0,l=children.length;i<l;i++){fn(children[i],i)}},"eachChildren");eachByQuery(node,".jsondiffpatch-arrow",function(_ref3){var parentNode=_ref3.parentNode,children=_ref3.children,style=_ref3.style;var arrowParent=parentNode;var svg=children[0];var path=svg.children[1];svg.style.display="none";var destination=getElementText(arrowParent.querySelector(".jsondiffpatch-moved-destination"));var container=arrowParent.parentNode;var destinationElem=void 0;eachChildren(container,function(child){if(child.getAttribute("data-key")===destination){destinationElem=child}});if(!destinationElem){return}try{var distance=destinationElem.offsetTop-arrowParent.offsetTop;svg.setAttribute("height",Math.abs(distance)+6);style.top=-8+(distance>0?0:distance)+"px";var curve=distance>0?"M30,0 Q-10,"+Math.round(distance/2)+" 26,"+(distance-4):"M30,"+-distance+" Q-10,"+Math.round(-distance/2)+" 26,4";path.setAttribute("d",curve);svg.style.display=""}catch(err){}})},"jsondiffpatchHtmlFormatterAdjustArrows");var AnnotatedFormatter=function(_BaseFormatter){inherits(AnnotatedFormatter2,_BaseFormatter);function AnnotatedFormatter2(){classCallCheck(this,AnnotatedFormatter2);var _this=possibleConstructorReturn(this,(AnnotatedFormatter2.__proto__||Object.getPrototypeOf(AnnotatedFormatter2)).call(this));_this.includeMoveDestinations=false;return _this}__name(AnnotatedFormatter2,"AnnotatedFormatter");createClass(AnnotatedFormatter2,[{key:"prepareContext",value:__name(function prepareContext(context){get(AnnotatedFormatter2.prototype.__proto__||Object.getPrototypeOf(AnnotatedFormatter2.prototype),"prepareContext",this).call(this,context);context.indent=function(levels){this.indentLevel=(this.indentLevel||0)+(typeof levels==="undefined"?1:levels);this.indentPad=new Array(this.indentLevel+1).join("&nbsp;&nbsp;")};context.row=function(json,htmlNote){context.out('<tr><td style="white-space: nowrap;"><pre class="jsondiffpatch-annotated-indent" style="display: inline-block">');context.out(context.indentPad);context.out('</pre><pre style="display: inline-block">');context.out(json);context.out('</pre></td><td class="jsondiffpatch-delta-note"><div>');context.out(htmlNote);context.out("</div></td></tr>")}},"prepareContext")},{key:"typeFormattterErrorFormatter",value:__name(function typeFormattterErrorFormatter(context,err){context.row("",'<pre class="jsondiffpatch-error">'+err+"</pre>")},"typeFormattterErrorFormatter")},{key:"formatTextDiffString",value:__name(function formatTextDiffString(context,value){var lines=this.parseTextDiff(value);context.out('<ul class="jsondiffpatch-textdiff">');for(var i=0,l=lines.length;i<l;i++){var line=lines[i];context.out('<li><div class="jsondiffpatch-textdiff-location">'+('<span class="jsondiffpatch-textdiff-line-number">'+line.location.line+'</span><span class="jsondiffpatch-textdiff-char">'+line.location.chr+'</span></div><div class="jsondiffpatch-textdiff-line">'));var pieces=line.pieces;for(var pieceIndex=0,piecesLength=pieces.length;pieceIndex<piecesLength;pieceIndex++){var piece=pieces[pieceIndex];context.out('<span class="jsondiffpatch-textdiff-'+piece.type+'">'+piece.text+"</span>")}context.out("</div></li>")}context.out("</ul>")},"formatTextDiffString")},{key:"rootBegin",value:__name(function rootBegin(context,type,nodeType){context.out('<table class="jsondiffpatch-annotated-delta">');if(type==="node"){context.row("{");context.indent()}if(nodeType==="array"){context.row('"_t": "a",',"Array delta (member names indicate array indices)")}},"rootBegin")},{key:"rootEnd",value:__name(function rootEnd(context,type){if(type==="node"){context.indent(-1);context.row("}")}context.out("</table>")},"rootEnd")},{key:"nodeBegin",value:__name(function nodeBegin(context,key,leftKey,type,nodeType){context.row("&quot;"+key+"&quot;: {");if(type==="node"){context.indent()}if(nodeType==="array"){context.row('"_t": "a",',"Array delta (member names indicate array indices)")}},"nodeBegin")},{key:"nodeEnd",value:__name(function nodeEnd(context,key,leftKey,type,nodeType,isLast){if(type==="node"){context.indent(-1)}context.row("}"+(isLast?"":","))},"nodeEnd")},{key:"format_unchanged",value:__name(function format_unchanged(){},"format_unchanged")},{key:"format_movedestination",value:__name(function format_movedestination(){},"format_movedestination")},{key:"format_node",value:__name(function format_node(context,delta,left){this.formatDeltaChildren(context,delta,left)},"format_node")}]);return AnnotatedFormatter2}(BaseFormatter);var wrapPropertyName=__name(function wrapPropertyName2(name){return'<pre style="display:inline-block">&quot;'+name+"&quot;</pre>"},"wrapPropertyName");var deltaAnnotations={added:__name(function added(delta,left,key,leftKey){var formatLegend=" <pre>([newValue])</pre>";if(typeof leftKey==="undefined"){return"new value"+formatLegend}if(typeof leftKey==="number"){return"insert at index "+leftKey+formatLegend}return"add property "+wrapPropertyName(leftKey)+formatLegend},"added"),modified:__name(function modified(delta,left,key,leftKey){var formatLegend=" <pre>([previousValue, newValue])</pre>";if(typeof leftKey==="undefined"){return"modify value"+formatLegend}if(typeof leftKey==="number"){return"modify at index "+leftKey+formatLegend}return"modify property "+wrapPropertyName(leftKey)+formatLegend},"modified"),deleted:__name(function deleted(delta,left,key,leftKey){var formatLegend=" <pre>([previousValue, 0, 0])</pre>";if(typeof leftKey==="undefined"){return"delete value"+formatLegend}if(typeof leftKey==="number"){return"remove index "+leftKey+formatLegend}return"delete property "+wrapPropertyName(leftKey)+formatLegend},"deleted"),moved:__name(function moved(delta,left,key,leftKey){return'move from <span title="(position to remove at original state)">'+("index "+leftKey+'</span> to <span title="(position to insert at final')+(' state)">index '+delta[1]+"</span>")},"moved"),textdiff:__name(function textdiff(delta,left,key,leftKey){var location=typeof leftKey==="undefined"?"":typeof leftKey==="number"?" at index "+leftKey:" at property "+wrapPropertyName(leftKey);return"text diff"+location+', format is <a href="https://code.google.com/p/google-diff-match-patch/wiki/Unidiff">a variation of Unidiff</a>'},"textdiff")};var formatAnyChange=__name(function formatAnyChange2(context,delta){var deltaType=this.getDeltaType(delta);var annotator=deltaAnnotations[deltaType];var htmlNote=annotator&&annotator.apply(annotator,Array.prototype.slice.call(arguments,1));var json=JSON.stringify(delta,null,2);if(deltaType==="textdiff"){json=json.split("\\n").join('\\n"+\n   "')}context.indent();context.row(json,htmlNote);context.indent(-1)},"formatAnyChange");AnnotatedFormatter.prototype.format_added=formatAnyChange;AnnotatedFormatter.prototype.format_modified=formatAnyChange;AnnotatedFormatter.prototype.format_deleted=formatAnyChange;AnnotatedFormatter.prototype.format_moved=formatAnyChange;AnnotatedFormatter.prototype.format_textdiff=formatAnyChange;var OPERATIONS={add:"add",remove:"remove",replace:"replace",move:"move"};(function(_BaseFormatter){inherits(JSONFormatter,_BaseFormatter);function JSONFormatter(){classCallCheck(this,JSONFormatter);var _this=possibleConstructorReturn(this,(JSONFormatter.__proto__||Object.getPrototypeOf(JSONFormatter)).call(this));_this.includeMoveDestinations=true;return _this}__name(JSONFormatter,"JSONFormatter");createClass(JSONFormatter,[{key:"prepareContext",value:__name(function prepareContext(context){get(JSONFormatter.prototype.__proto__||Object.getPrototypeOf(JSONFormatter.prototype),"prepareContext",this).call(this,context);context.result=[];context.path=[];context.pushCurrentOp=function(obj){var op=obj.op,value=obj.value;var val={op,path:this.currentPath()};if(typeof value!=="undefined"){val.value=value}this.result.push(val)};context.pushMoveOp=function(to){var from=this.currentPath();this.result.push({op:OPERATIONS.move,from,path:this.toPath(to)})};context.currentPath=function(){return"/"+this.path.join("/")};context.toPath=function(toPath){var to=this.path.slice();to[to.length-1]=toPath;return"/"+to.join("/")}},"prepareContext")},{key:"typeFormattterErrorFormatter",value:__name(function typeFormattterErrorFormatter(context,err){context.out("[ERROR] "+err)},"typeFormattterErrorFormatter")},{key:"rootBegin",value:__name(function rootBegin(){},"rootBegin")},{key:"rootEnd",value:__name(function rootEnd(){},"rootEnd")},{key:"nodeBegin",value:__name(function nodeBegin(_ref,key,leftKey){var path=_ref.path;path.push(leftKey)},"nodeBegin")},{key:"nodeEnd",value:__name(function nodeEnd(_ref2){var path=_ref2.path;path.pop()},"nodeEnd")},{key:"format_unchanged",value:__name(function format_unchanged(){},"format_unchanged")},{key:"format_movedestination",value:__name(function format_movedestination(){},"format_movedestination")},{key:"format_node",value:__name(function format_node(context,delta,left){this.formatDeltaChildren(context,delta,left)},"format_node")},{key:"format_added",value:__name(function format_added(context,delta){context.pushCurrentOp({op:OPERATIONS.add,value:delta[0]})},"format_added")},{key:"format_modified",value:__name(function format_modified(context,delta){context.pushCurrentOp({op:OPERATIONS.replace,value:delta[1]})},"format_modified")},{key:"format_deleted",value:__name(function format_deleted(context){context.pushCurrentOp({op:OPERATIONS.remove})},"format_deleted")},{key:"format_moved",value:__name(function format_moved(context,delta){var to=delta[1];context.pushMoveOp(to)},"format_moved")},{key:"format_textdiff",value:__name(function format_textdiff(){throw new Error("Not implemented")},"format_textdiff")},{key:"format",value:__name(function format(delta,left){var context={};this.prepareContext(context);this.recurse(context,delta,left);return context.result},"format")}]);return JSONFormatter})(BaseFormatter);function chalkColor(name){return chalk$1&&chalk$1[name]||function(){for(var _len=arguments.length,args=Array(_len),_key=0;_key<_len;_key++){args[_key]=arguments[_key]}return args}}__name(chalkColor,"chalkColor");var colors={added:chalkColor("green"),deleted:chalkColor("red"),movedestination:chalkColor("gray"),moved:chalkColor("yellow"),unchanged:chalkColor("gray"),error:chalkColor("white.bgRed"),textDiffLine:chalkColor("gray")};(function(_BaseFormatter){inherits(ConsoleFormatter,_BaseFormatter);function ConsoleFormatter(){classCallCheck(this,ConsoleFormatter);var _this=possibleConstructorReturn(this,(ConsoleFormatter.__proto__||Object.getPrototypeOf(ConsoleFormatter)).call(this));_this.includeMoveDestinations=false;return _this}__name(ConsoleFormatter,"ConsoleFormatter");createClass(ConsoleFormatter,[{key:"prepareContext",value:__name(function prepareContext(context){get(ConsoleFormatter.prototype.__proto__||Object.getPrototypeOf(ConsoleFormatter.prototype),"prepareContext",this).call(this,context);context.indent=function(levels){this.indentLevel=(this.indentLevel||0)+(typeof levels==="undefined"?1:levels);this.indentPad=new Array(this.indentLevel+1).join("  ");this.outLine()};context.outLine=function(){this.buffer.push("\n"+(this.indentPad||""))};context.out=function(){for(var _len2=arguments.length,args=Array(_len2),_key2=0;_key2<_len2;_key2++){args[_key2]=arguments[_key2]}for(var i=0,l=args.length;i<l;i++){var lines=args[i].split("\n");var text=lines.join("\n"+(this.indentPad||""));if(this.color&&this.color[0]){text=this.color[0](text)}this.buffer.push(text)}};context.pushColor=function(color){this.color=this.color||[];this.color.unshift(color)};context.popColor=function(){this.color=this.color||[];this.color.shift()}},"prepareContext")},{key:"typeFormattterErrorFormatter",value:__name(function typeFormattterErrorFormatter(context,err){context.pushColor(colors.error);context.out("[ERROR]"+err);context.popColor()},"typeFormattterErrorFormatter")},{key:"formatValue",value:__name(function formatValue(context,value){context.out(JSON.stringify(value,null,2))},"formatValue")},{key:"formatTextDiffString",value:__name(function formatTextDiffString(context,value){var lines=this.parseTextDiff(value);context.indent();for(var i=0,l=lines.length;i<l;i++){var line=lines[i];context.pushColor(colors.textDiffLine);context.out(line.location.line+","+line.location.chr+" ");context.popColor();var pieces=line.pieces;for(var pieceIndex=0,piecesLength=pieces.length;pieceIndex<piecesLength;pieceIndex++){var piece=pieces[pieceIndex];context.pushColor(colors[piece.type]);context.out(piece.text);context.popColor()}if(i<l-1){context.outLine()}}context.indent(-1)},"formatTextDiffString")},{key:"rootBegin",value:__name(function rootBegin(context,type,nodeType){context.pushColor(colors[type]);if(type==="node"){context.out(nodeType==="array"?"[":"{");context.indent()}},"rootBegin")},{key:"rootEnd",value:__name(function rootEnd(context,type,nodeType){if(type==="node"){context.indent(-1);context.out(nodeType==="array"?"]":"}")}context.popColor()},"rootEnd")},{key:"nodeBegin",value:__name(function nodeBegin(context,key,leftKey,type,nodeType){context.pushColor(colors[type]);context.out(leftKey+": ");if(type==="node"){context.out(nodeType==="array"?"[":"{");context.indent()}},"nodeBegin")},{key:"nodeEnd",value:__name(function nodeEnd(context,key,leftKey,type,nodeType,isLast){if(type==="node"){context.indent(-1);context.out(nodeType==="array"?"]":"}"+(isLast?"":","))}if(!isLast){context.outLine()}context.popColor()},"nodeEnd")},{key:"format_unchanged",value:__name(function format_unchanged(context,delta,left){if(typeof left==="undefined"){return}this.formatValue(context,left)},"format_unchanged")},{key:"format_movedestination",value:__name(function format_movedestination(context,delta,left){if(typeof left==="undefined"){return}this.formatValue(context,left)},"format_movedestination")},{key:"format_node",value:__name(function format_node(context,delta,left){this.formatDeltaChildren(context,delta,left)},"format_node")},{key:"format_added",value:__name(function format_added(context,delta){this.formatValue(context,delta[0])},"format_added")},{key:"format_modified",value:__name(function format_modified(context,delta){context.pushColor(colors.deleted);this.formatValue(context,delta[0]);context.popColor();context.out(" => ");context.pushColor(colors.added);this.formatValue(context,delta[1]);context.popColor()},"format_modified")},{key:"format_deleted",value:__name(function format_deleted(context,delta){this.formatValue(context,delta[0])},"format_deleted")},{key:"format_moved",value:__name(function format_moved(context,delta){context.out("==> "+delta[1])},"format_moved")},{key:"format_textdiff",value:__name(function format_textdiff(context,delta){this.formatTextDiffString(context,delta[0])},"format_textdiff")}]);return ConsoleFormatter})(BaseFormatter);var defaultInstance$4=void 0;function diff(){if(!defaultInstance$4){defaultInstance$4=new DiffPatcher}return defaultInstance$4.diff.apply(defaultInstance$4,arguments)}__name(diff,"diff");function patch(){if(!defaultInstance$4){defaultInstance$4=new DiffPatcher}return defaultInstance$4.patch.apply(defaultInstance$4,arguments)}__name(patch,"patch");function reverse(){if(!defaultInstance$4){defaultInstance$4=new DiffPatcher}return defaultInstance$4.reverse.apply(defaultInstance$4,arguments)}__name(reverse,"reverse");const proteinAlphabet={A:{value:"A",name:"Alanine",threeLettersName:"Ala",hydrophobicity:1.8,colorByFamily:"#00FFFF",color:"hsl(327.3, 100%, 69%)",mass:89.1},R:{value:"R",name:"Arginine",threeLettersName:"Arg",hydrophobicity:-4.5,colorByFamily:"#FFC0CB",color:"hsl(258.1, 100%, 69%)",mass:174.2},N:{value:"N",name:"Asparagine",threeLettersName:"Asn",hydrophobicity:-3.5,colorByFamily:"#D3D3D3",color:"hsl(268.9, 100%, 69%)",mass:132.1},D:{value:"D",name:"Aspartic acid",threeLettersName:"Asp",hydrophobicity:-3.5,colorByFamily:"#EE82EE",color:"hsl(268.9, 100%, 69%)",mass:133.1},C:{value:"C",name:"Cysteine",threeLettersName:"Cys",hydrophobicity:2.5,colorByFamily:"#FFFF00",color:"hsl(335.1, 100%, 69%)",mass:121.2},E:{value:"E",name:"Glutamic acid",threeLettersName:"Glu",hydrophobicity:-3.5,colorByFamily:"#EE82EE",color:"hsl(268.9, 100%, 69%)",mass:147.1},Q:{value:"Q",name:"Glutamine",threeLettersName:"Gln",hydrophobicity:-3.5,colorByFamily:"#D3D3D3",color:"hsl(268.9, 100%, 69%)",mass:146.2},G:{value:"G",name:"Glycine",threeLettersName:"Gly",hydrophobicity:-.4,colorByFamily:"#00FFFF",color:"hsl(303.1, 100%, 69%)",mass:75.1},H:{value:"H",name:"Histidine",threeLettersName:"His",hydrophobicity:-3.2,colorByFamily:"#FFC0CB",color:"hsl(272.2, 100%, 69%)",mass:155.2},I:{value:"I",name:"Isoleucine ",threeLettersName:"Ile",hydrophobicity:4.5,colorByFamily:"#00FFFF",color:"hsl(356.9, 100%, 69%)",mass:131.2},L:{value:"L",name:"Leucine",threeLettersName:"Leu",hydrophobicity:3.8,colorByFamily:"#00FFFF",color:"hsl(349.4, 100%, 69%)",mass:131.2},K:{value:"K",name:"Lysine",threeLettersName:"Lys",hydrophobicity:-3.9,colorByFamily:"#FFC0CB",color:"hsl(264.7, 100%, 69%)",mass:146.2},M:{value:"M",name:"Methionine",threeLettersName:"Met",hydrophobicity:1.9,colorByFamily:"#FFFF00",color:"hsl(328.5, 100%, 69%)",mass:149.2},F:{value:"F",name:"Phenylalanine",threeLettersName:"Phe",hydrophobicity:2.8,colorByFamily:"#FFA500",color:"hsl(338.4, 100%, 69%)",mass:165.2},P:{value:"P",name:"Proline",threeLettersName:"Pro",hydrophobicity:-1.6,colorByFamily:"#00FFFF",color:"hsl(289.9, 100%, 69%)",mass:115.1},S:{value:"S",name:"Serine",threeLettersName:"Ser",hydrophobicity:-.8,colorByFamily:"#90EE90",color:"hsl(298.6, 100%, 69%)",mass:105.1},T:{value:"T",name:"Threonine",threeLettersName:"Thr",hydrophobicity:-.7,colorByFamily:"#90EE90",color:"hsl(299.8, 100%, 69%)",mass:119.1},U:{value:"U",name:"Selenocysteine",threeLettersName:"Sec",colorByFamily:"#FF0000",color:"hsl(0, 100%, 69%)",mass:168.1},W:{value:"W",name:"Tryptophan",threeLettersName:"Trp",hydrophobicity:-.9,colorByFamily:"#FFA500",color:"hsl(297.6, 100%, 69%)",mass:204.2},Y:{value:"Y",name:"Tyrosine",threeLettersName:"Tyr",hydrophobicity:-1.3,colorByFamily:"#FFA500",color:"hsl(293.2, 100%, 69%)",mass:181.2},V:{value:"V",name:"Valine",threeLettersName:"Val",hydrophobicity:4.2,colorByFamily:"#00FFFF",color:"hsl(353.6, 100%, 69%)",mass:117.1},"*":{value:"*",name:"Stop",threeLettersName:"Stop",colorByFamily:"#FF0000",color:"hsl(0, 100%, 69%)",mass:0},".":{value:".",name:"Gap",threeLettersName:"Gap",colorByFamily:"#FF0000",color:"hsl(0, 100%, 69%)",mass:0},"-":{value:"-",name:"Gap",threeLettersName:"Gap",colorByFamily:"#FF0000",color:"hsl(0, 100%, 69%)",mass:0},B:{value:"B",threeLettersName:"ND",colorByFamily:"#D3D3D3",color:"hsl(268.9, 100%, 69%)",isAmbiguous:true,name:"B",aliases:"ND",mass:0},J:{value:"J",threeLettersName:"IL",colorByFamily:"#00FFFF",color:"hsl(352, 100%, 69%)",isAmbiguous:true,name:"J",aliases:"IL",mass:0},X:{value:"X",threeLettersName:"ACDEFGHIKLMNPQRSTVWY",colorByFamily:"#FFFFFF",color:"hsl(60, 100%, 69%)",isAmbiguous:true,name:"X",aliases:"ACDEFGHIKLMNPQRSTVWY",mass:0},Z:{value:"Z",threeLettersName:"QE",colorByFamily:"#D3D3D3",color:"hsl(268.9, 100%, 69%)",isAmbiguous:true,name:"Z",aliases:"QE",mass:0}};const threeLetterSequenceStringToAminoAcidMap={gct:proteinAlphabet.A,gcc:proteinAlphabet.A,gca:proteinAlphabet.A,gcg:proteinAlphabet.A,gcu:proteinAlphabet.A,cgt:proteinAlphabet.R,cgc:proteinAlphabet.R,cga:proteinAlphabet.R,cgg:proteinAlphabet.R,aga:proteinAlphabet.R,agg:proteinAlphabet.R,cgu:proteinAlphabet.R,aat:proteinAlphabet.N,aac:proteinAlphabet.N,aau:proteinAlphabet.N,gat:proteinAlphabet.D,gac:proteinAlphabet.D,gau:proteinAlphabet.D,tgt:proteinAlphabet.C,tgc:proteinAlphabet.C,ugu:proteinAlphabet.C,ugc:proteinAlphabet.C,gaa:proteinAlphabet.E,gag:proteinAlphabet.E,caa:proteinAlphabet.Q,cag:proteinAlphabet.Q,ggt:proteinAlphabet.G,ggc:proteinAlphabet.G,gga:proteinAlphabet.G,ggg:proteinAlphabet.G,ggu:proteinAlphabet.G,cat:proteinAlphabet.H,cac:proteinAlphabet.H,cau:proteinAlphabet.H,att:proteinAlphabet.I,atc:proteinAlphabet.I,ata:proteinAlphabet.I,auu:proteinAlphabet.I,auc:proteinAlphabet.I,aua:proteinAlphabet.I,ctt:proteinAlphabet.L,ctc:proteinAlphabet.L,cta:proteinAlphabet.L,ctg:proteinAlphabet.L,tta:proteinAlphabet.L,ttg:proteinAlphabet.L,cuu:proteinAlphabet.L,cuc:proteinAlphabet.L,cua:proteinAlphabet.L,cug:proteinAlphabet.L,uua:proteinAlphabet.L,uug:proteinAlphabet.L,aaa:proteinAlphabet.K,aag:proteinAlphabet.K,atg:proteinAlphabet.M,aug:proteinAlphabet.M,ttt:proteinAlphabet.F,ttc:proteinAlphabet.F,uuu:proteinAlphabet.F,uuc:proteinAlphabet.F,cct:proteinAlphabet.P,ccc:proteinAlphabet.P,cca:proteinAlphabet.P,ccg:proteinAlphabet.P,ccu:proteinAlphabet.P,tct:proteinAlphabet.S,tcc:proteinAlphabet.S,tca:proteinAlphabet.S,tcg:proteinAlphabet.S,agt:proteinAlphabet.S,agc:proteinAlphabet.S,ucu:proteinAlphabet.S,ucc:proteinAlphabet.S,uca:proteinAlphabet.S,ucg:proteinAlphabet.S,agu:proteinAlphabet.S,act:proteinAlphabet.T,acc:proteinAlphabet.T,aca:proteinAlphabet.T,acg:proteinAlphabet.T,acu:proteinAlphabet.T,tgg:proteinAlphabet.W,ugg:proteinAlphabet.W,tat:proteinAlphabet.Y,tac:proteinAlphabet.Y,uau:proteinAlphabet.Y,uac:proteinAlphabet.Y,gtt:proteinAlphabet.V,gtc:proteinAlphabet.V,gta:proteinAlphabet.V,gtg:proteinAlphabet.V,guu:proteinAlphabet.V,guc:proteinAlphabet.V,gua:proteinAlphabet.V,gug:proteinAlphabet.V,taa:proteinAlphabet["*"],tag:proteinAlphabet["*"],tga:proteinAlphabet["*"],"...":proteinAlphabet["."],"---":proteinAlphabet["-"]};const degenerateDnaToAminoAcidMap=lodashExports.invert(aminoAcidToDegenerateDnaMap);function getAminoAcidFromSequenceTriplet(sequenceString){sequenceString=sequenceString.toLowerCase();if(sequenceString.length!==3){throw new Error("must pass a string of length 3")}let aa=threeLetterSequenceStringToAminoAcidMap[sequenceString];if(aa){return aa}const letter=degenerateDnaToAminoAcidMap[sequenceString.replace("x","n")]||"x";return proteinAlphabet[letter.toUpperCase()]}__name(getAminoAcidFromSequenceTriplet,"getAminoAcidFromSequenceTriplet");function getAminoAcidDataForEachBaseOfDna(originalSequenceString,forward,optionalSubrangeRange,isProteinSequence){let originalSequenceStringLength=isProteinSequence?originalSequenceString.length*3:originalSequenceString.length;let sequenceString=originalSequenceString;let startOffset=0;if(optionalSubrangeRange){sequenceString=getSequenceWithinRange(optionalSubrangeRange,originalSequenceString);startOffset=optionalSubrangeRange.start}let sequenceStringLength=isProteinSequence?sequenceString.length*3:sequenceString.length;let aminoAcidDataForEachBaseOfDNA=[];let codonRange;let revCompGapLength=0;let aminoAcidIndex=0;if(!forward){aminoAcidIndex=Math.floor((sequenceStringLength-1)/3);revCompGapLength=sequenceStringLength%3;codonRange=translateRange({start:0,end:revCompGapLength-1},startOffset,originalSequenceStringLength);if(revCompGapLength>0){for(let i=0;i<revCompGapLength;i++){aminoAcidDataForEachBaseOfDNA.push({aminoAcid:getAminoAcidFromSequenceTriplet("xxx"),positionInCodon:revCompGapLength-i-1,aminoAcidIndex,sequenceIndex:codonRange.start+i,codonRange,fullCodon:false})}aminoAcidIndex--}}for(let index2=2+revCompGapLength;index2<sequenceStringLength;index2+=3){let aminoAcid;if(isProteinSequence){aminoAcid=proteinAlphabet[sequenceString[(index2-2)/3].toUpperCase()]}else{let triplet=sequenceString.slice(index2-2,index2+1);if(!forward){triplet=getReverseComplementSequenceString(triplet)}aminoAcid=getAminoAcidFromSequenceTriplet(triplet)}codonRange=translateRange({start:index2-2,end:index2},startOffset,originalSequenceStringLength);aminoAcidDataForEachBaseOfDNA.push({aminoAcid,positionInCodon:forward?0:2,aminoAcidIndex,sequenceIndex:codonRange.start,codonRange,fullCodon:true});aminoAcidDataForEachBaseOfDNA.push({aminoAcid,positionInCodon:1,aminoAcidIndex,sequenceIndex:codonRange.start+1,codonRange,fullCodon:true});aminoAcidDataForEachBaseOfDNA.push({aminoAcid,positionInCodon:forward?2:0,aminoAcidIndex,sequenceIndex:codonRange.start+2,codonRange,fullCodon:true});if(forward){aminoAcidIndex++}else{aminoAcidIndex--}}let lengthOfEndBpsNotCoveredByAminoAcids=sequenceStringLength-aminoAcidDataForEachBaseOfDNA.length;codonRange=translateRange({start:sequenceStringLength-lengthOfEndBpsNotCoveredByAminoAcids,end:sequenceStringLength-1},startOffset,originalSequenceStringLength);for(let j=0;j<lengthOfEndBpsNotCoveredByAminoAcids;j++){aminoAcidDataForEachBaseOfDNA.push({aminoAcid:getAminoAcidFromSequenceTriplet("xxx"),positionInCodon:j,aminoAcidIndex,sequenceIndex:codonRange.start+j,fullCodon:false,codonRange})}if(sequenceStringLength!==aminoAcidDataForEachBaseOfDNA.length){throw new Error("something went wrong!")}return aminoAcidDataForEachBaseOfDNA}__name(getAminoAcidDataForEachBaseOfDna,"getAminoAcidDataForEachBaseOfDna");const annotationTypes=["features","warnings","assemblyPieces","lineageAnnotations","parts","cutsites","orfs","translations","primers","guides"];const modifiableTypes=["features","assemblyPieces","lineageAnnotations","warnings","parts","translations","primers","guides"];function filterSequenceString(sequenceString,additionalValidChars="",charOverrides){if(sequenceString){return sequenceString.replace(new RegExp(`[^${charOverrides||`atgcyrswkmbvdhnu${additionalValidChars.split("").join("\\")}`}]`,"gi"),"")}else{return sequenceString}}__name(filterSequenceString,"filterSequenceString");function tidyUpAnnotation(_annotation,{sequenceData={},convertAnnotationsFromAAIndices,annotationType,provideNewIdsForAnnotations,doNotProvideIdsForAnnotations,messages=[],mutative,allowNonStandardGenbankTypes,featureTypes}){const{size,circular,isProtein}=sequenceData;if(!_annotation||typeof _annotation!=="object"){messages.push("Invalid annotation detected and removed");return false}let annotation=_annotation;if(!mutative){annotation=lodashExports.cloneDeep(_annotation)}annotation.annotationTypePlural=annotationType;if(!annotation.name||typeof annotation.name!=="string"){messages.push('Unable to detect valid name for annotation, setting name to "Untitled annotation"');annotation.name="Untitled annotation"}if(provideNewIdsForAnnotations){annotation.id=bsonObjectId().str}if(!annotation.id&&annotation.id!==0&&!doNotProvideIdsForAnnotations){annotation.id=bsonObjectId().str;messages.push("Unable to detect valid ID for annotation, setting ID to "+annotation.id)}coerceLocation({isProtein,location:annotation,convertAnnotationsFromAAIndices,size,messages,circular,name:annotation.name});annotation.locations&&annotation.locations.forEach(location=>{coerceLocation({isProtein,location,convertAnnotationsFromAAIndices,size,messages,circular,name:annotation.name})});if(isProtein||annotation.forward===true||annotation.forward==="true"||annotation.strand===1||annotation.strand==="1"||annotation.strand==="+"){annotation.forward=true;annotation.strand=1}else{annotation.forward=false;annotation.strand=-1}if(!annotation.type||typeof annotation.type!=="string"||!lodashExports.some(featureTypes||getFeatureTypes(),featureType=>{if(featureType.toLowerCase()===annotation.type.toLowerCase()){annotation.type=featureType;return true}if(allowNonStandardGenbankTypes||typeof window!=="undefined"&&lodashExports.get(window,"tg_allowNonStandardGenbankTypes")||typeof global!=="undefined"&&lodashExports.get(global,"tg_allowNonStandardGenbankTypes"))return true;return false})){messages.push("Invalid annotation type detected:  "+annotation.type+" for "+annotation.name+". set type to misc_feature");annotation.type="misc_feature"}if(annotation.notes&&typeof annotation.notes==="string"){try{annotation.notes=JSON.parse(annotation.notes)}catch(error){console.info(`warning 33y00a0912 - couldn't parse notes for ${annotation.name||""} ${annotation.notes}:`,error)}}if(!annotation.color){annotation.color=getFeatureToColorMap()[annotation.type]}return annotation}__name(tidyUpAnnotation,"tidyUpAnnotation");function coerceLocation({location,convertAnnotationsFromAAIndices,size,isProtein,messages,circular,name}){location.start=parseInt(location.start,10);location.end=parseInt(location.end,10);if(convertAnnotationsFromAAIndices){location.start=location.start*3;location.end=location.end*3+2}if(location.start<0||!(location.start<=size-1)||location.start>size-1){messages.push("Invalid annotation start: "+location.start+" detected for "+location.name+" and set to size: "+size);location.start=size-(isProtein?3:1)}if(location.end<0||!(location.end<=size-1)||location.end>size-1){messages.push("Invalid annotation end:  "+location.end+" detected for "+location.name+" and set to seq size: "+size);location.end=size-1}if(location.start>location.end&&circular===false){messages.push("Invalid circular annotation detected for "+name+". end set to 1");location.end=size}}__name(coerceLocation,"coerceLocation");function filterAminoAcidSequenceString(sequenceString,options){options=options||{};if(options.includeStopCodon){return sequenceString.replace(/[^xtgalmfwkqespvicyhrndu.*]/gi,"")}return sequenceString.replace(/[^xtgalmfwkqespvicyhrndu]/gi,"")}__name(filterAminoAcidSequenceString,"filterAminoAcidSequenceString");function getDegenerateDnaStringFromAAString(aaString){return aaString.split("").map(char=>aminoAcidToDegenerateDnaMap[char.toLowerCase()]||"nnn").join("")}__name(getDegenerateDnaStringFromAAString,"getDegenerateDnaStringFromAAString");function tidyUpSequenceData(pSeqData,options={}){const{annotationsAsObjects,logMessages,removeUnwantedChars,additionalValidChars,noTranslationData,charOverrides,doNotProvideIdsForAnnotations,proteinFilterOptions,noCdsTranslations,convertAnnotationsFromAAIndices}=options;let seqData=lodashExports.cloneDeep(pSeqData);const response={messages:[]};if(!seqData){seqData={}}if(!seqData.sequence){seqData.sequence=""}if(!seqData.proteinSequence){seqData.proteinSequence=""}let needsBackTranslation=false;if(seqData.isProtein){seqData.circular=false;if(!seqData.proteinSequence&&seqData.proteinSequence!==""){seqData.proteinSequence=seqData.sequence}if(!seqData.sequence||seqData.sequence.length!==seqData.proteinSequence.length*3){needsBackTranslation=true}}if(seqData.isRna){seqData.sequence=seqData.sequence.replace(/t/gi,"u")}if(removeUnwantedChars){if(seqData.isProtein){seqData.proteinSequence=filterAminoAcidSequenceString(seqData.proteinSequence,__spreadValues({includeStopCodon:true},proteinFilterOptions))}else{seqData.sequence=filterSequenceString(seqData.sequence,`${additionalValidChars||""}${seqData.isRna||seqData.isMixedRnaAndDna?"u":""}`,charOverrides)}}if(seqData.isProtein){if(needsBackTranslation){seqData.sequence=getDegenerateDnaStringFromAAString(seqData.proteinSequence)}seqData.aminoAcidDataForEachBaseOfDNA=getAminoAcidDataForEachBaseOfDna(seqData.proteinSequence,true,null,true)}seqData.size=seqData.noSequence?seqData.size:seqData.sequence.length;seqData.proteinSize=seqData.noSequence?seqData.proteinSize:seqData.proteinSequence.length;if(seqData.circular==="false"||seqData.circular==-1||seqData.circular===false||!seqData.circular&&seqData.sequenceTypeCode!=="CIRCULAR_DNA"){seqData.circular=false}else{seqData.circular=true}const featureTypes=getFeatureTypes();annotationTypes.forEach(annotationType=>{if(!Array.isArray(seqData[annotationType])){if(typeof seqData[annotationType]==="object"){seqData[annotationType]=Object.keys(seqData[annotationType]).map(key=>{return seqData[annotationType][key]})}else{seqData[annotationType]=[]}}seqData[annotationType]=seqData[annotationType].filter(annotation=>{return tidyUpAnnotation(annotation,__spreadProps(__spreadValues({},options),{featureTypes,sequenceData:seqData,convertAnnotationsFromAAIndices,mutative:true,annotationType}))})});if(!noTranslationData){seqData.translations=lodashExports.flatMap(seqData.translations,translation=>{if(noCdsTranslations&&translation.translationType==="CDS Feature"){return[]}if(!translation.aminoAcids&&!seqData.noSequence){translation.aminoAcids=getAminoAcidDataForEachBaseOfDna(seqData.sequence,translation.forward,translation)}return translation})}if(annotationsAsObjects){annotationTypes.forEach(name=>{seqData[name]=seqData[name].reduce((acc,item)=>{let itemId;if(item.id||item.id===0){itemId=item.id}else{itemId=bsonObjectId().str;if(!doNotProvideIdsForAnnotations){item.id=itemId}}acc[itemId]=item;return acc},{})})}if(logMessages&&response.messages.length>0){console.info("tidyUpSequenceData messages:",response.messages)}return seqData}__name(tidyUpSequenceData,"tidyUpSequenceData");const getDiffFromSeqs=__name((oldData,newData,{ignoreKeys=[]}={})=>{oldData=tidyUpSequenceData(oldData,{annotationsAsObjects:true,noTranslationData:true});newData=tidyUpSequenceData(newData,{annotationsAsObjects:true,noTranslationData:true});[oldData,newData].forEach(d=>{["cutsites","orfs","filteredFeatures","size","fromFileUpload","description","materiallyAvailable",...ignoreKeys].forEach(prop=>{delete d[prop]});if(d.translations){lodashExports.forEach(d.translations,(translation,key)=>{if(translation.translationType&&translation.translationType!=="User Created"){delete d.translations[key]}else{delete translation.aminoAcids}})}});return diff(oldData,newData)},"getDiffFromSeqs");const patchSeqWithDiff=__name((oldData,diff2,{ignoreKeys=[]}={})=>{ignoreKeys.forEach(k=>{delete diff2[k]});return patch(tidyUpSequenceData(lodashExports.cloneDeep(oldData),{annotationsAsObjects:true}),diff2)},"patchSeqWithDiff");const reverseSeqDiff=__name(diff2=>{return reverse(diff2)},"reverseSeqDiff");function getAllInsertionsInSeqReads(seqReads){let allInsertionsInSeqReads=[];seqReads.forEach(seqRead=>{const splitSeqRead=seqRead.cigar.match(/([0-9]*[MDI])/g);for(let componentI=0;componentI<splitSeqRead.length;componentI++){if(splitSeqRead[componentI].slice(-1)==="I"){let bpPosOfInsertion=seqRead.pos;const numberOfInsertions=Number(splitSeqRead[componentI].slice(0,-1));for(let i=0;i<componentI;i++){if(splitSeqRead[i].slice(-1)!=="I"){const previousComponentNumber=Number(splitSeqRead[i].slice(0,-1));bpPosOfInsertion+=previousComponentNumber}}let insertionInfo={bpPos:bpPosOfInsertion,number:numberOfInsertions};allInsertionsInSeqReads.push(insertionInfo)}}});let sortedInsertions=allInsertionsInSeqReads.sort((a,b)=>{return a.bpPos-b.bpPos});for(let i=0;i<sortedInsertions.length-1;i++){if(sortedInsertions[i].bpPos===sortedInsertions[i+1].bpPos){if(sortedInsertions[i].number>sortedInsertions[i+1].number){sortedInsertions.splice(i+1,1);i--}else if(sortedInsertions[i].number<sortedInsertions[i+1].number){sortedInsertions.splice(i,1);i--}else if(sortedInsertions[i].number===sortedInsertions[i+1].number){sortedInsertions.splice(i,1);i--}}}return sortedInsertions}__name(getAllInsertionsInSeqReads,"getAllInsertionsInSeqReads");function annotateSingleSeq({fullSeq,searchSeq}){const fullSeqId=fullSeq.id||"fullSeqId";const searchSeqId=searchSeq.id||"searchSeqId";const results=autoAnnotate({seqsToAnnotateById:{[fullSeqId]:__spreadProps(__spreadValues({},fullSeq),{id:fullSeqId})},annotationsToCheckById:{[searchSeqId]:__spreadProps(__spreadValues({},searchSeq),{id:searchSeqId})},compareName:false});if(results&&results[fullSeqId]){return{matches:results[fullSeqId]}}else{return{matches:[]}}}__name(annotateSingleSeq,"annotateSingleSeq");const aminoAcidToDegenerateRnaMap={"-":"---",".":"...","*":"trr",a:"gcn",b:"ray",c:"ugy",d:"gay",e:"gar",f:"uuy",g:"ggn",h:"cay",i:"auh",j:"hun",k:"aar",l:"yun",m:"aug",n:"aay",o:"uag",p:"ccn",q:"car",r:"mgn",s:"wsn",t:"acn",u:"uga",v:"gun",w:"ugg",x:"nnn",y:"uay",z:"sar"};function getDegenerateRnaStringFromAAString(aaString){return aaString.split("").map(char=>aminoAcidToDegenerateRnaMap[char.toLowerCase()]||"nnn").join("")}__name(getDegenerateRnaStringFromAAString,"getDegenerateRnaStringFromAAString");function getVirtualDigest({cutsites,sequenceLength,isCircular,computePartialDigest,computePartialDigestDisabled,computeDigestDisabled}){let fragments=[];const overlappingEnzymes=[];const pairs=[];const sortedCutsites=cutsites.sort((a,b)=>{return a.topSnipPosition-b.topSnipPosition});sortedCutsites.forEach((cutsite1,index2)=>{if(computePartialDigest&&!computePartialDigestDisabled){sortedCutsites.forEach((cs,index22)=>{pairs.push([cutsite1,sortedCutsites[index22]])})}if(!computeDigestDisabled){pairs.push([cutsite1,sortedCutsites[index2+1]?sortedCutsites[index2+1]:sortedCutsites[0]])}});pairs.forEach(([cut1,cut2])=>{const start=normalizePositionByRangeLength(cut1.topSnipPosition,sequenceLength);const end=normalizePositionByRangeLength(cut2.topSnipPosition-1,sequenceLength);if(!isCircular&&start>end){const frag1={start,end:sequenceLength-1,cut1,cut2:{type:"endOfSeq",restrictionEnzyme:{name:"End Of Seq"}}};const frag2={start:0,end,cut1:{type:"startOfSeq",restrictionEnzyme:{name:"Start Of Seq"}},cut2};fragments.push(addSizeIdName(frag1,sequenceLength));fragments.push(addSizeIdName(frag2,sequenceLength))}else{const frag={cut1,cut2,start,end};fragments.push(addSizeIdName(frag,sequenceLength))}});fragments=fragments.filter(fragment=>{if(!fragment.size){overlappingEnzymes.push(fragment);return false}return true});return{computePartialDigestDisabled,computeDigestDisabled,fragments,overlappingEnzymes}}__name(getVirtualDigest,"getVirtualDigest");function addSizeIdName(frag,sequenceLength){const size=getRangeLength({start:frag.start,end:frag.end},sequenceLength);const name=`${lodashExports.get(frag,"cut1.restrictionEnzyme.name","Untitled Cutsite")} -- ${lodashExports.get(frag,"cut2.restrictionEnzyme.name","Untitled Cutsite")} ${size} bps`;return __spreadProps(__spreadValues({},frag),{size,name,id:frag.start+"-"+frag.end+"-"+size+"-"})}__name(addSizeIdName,"addSizeIdName");function isEnzymeType2S(e){return e.site.length<e.topSnipOffset||e.site.length<e.bottomSnipOffset}__name(isEnzymeType2S,"isEnzymeType2S");function insertGapsIntoRefSeq(refSeq,seqReads){let refSeqWithGaps=refSeq.split("");const allInsertionsInSeqReads=getAllInsertionsInSeqReads(seqReads);for(let i=0;i<allInsertionsInSeqReads.length;i++){const bpPosOfInsertion=allInsertionsInSeqReads[i].bpPos;const numberOfInsertions=allInsertionsInSeqReads[i].number;let insertionGaps="";for(let gapI=0;gapI<numberOfInsertions;gapI++){insertionGaps+="-"}refSeqWithGaps.splice(bpPosOfInsertion-1,0,insertionGaps);for(let posI=i+1;posI<allInsertionsInSeqReads.length;posI++){allInsertionsInSeqReads[posI].bpPos+=1}}return refSeqWithGaps.join("")}__name(insertGapsIntoRefSeq,"insertGapsIntoRefSeq");var spliceString=__name(function spliceSlice(str,index2,count,add){return str.slice(0,index2)+(add||"")+str.slice(index2+count)},"spliceSlice");const spliceString$1=getDefaultExportFromCjs(spliceString);function adjustBpsToReplaceOrInsert(bpString,insertString="",caretPositionOrRange){let stringToReturn=bpString;if(caretPositionOrRange&&caretPositionOrRange.start>-1){if(getRangeLength(caretPositionOrRange,bpString.length)===bpString.length){return insertString}const ranges=splitRangeIntoTwoPartsIfItIsCircular(invertRange(caretPositionOrRange,bpString.length));stringToReturn="";ranges.forEach((range,index2)=>{stringToReturn+=getSequenceWithinRange(range,bpString);if(ranges.length===1){if(isPositionWithinRange(0,range,bpString.length,true,true)){stringToReturn=stringToReturn+insertString}else{stringToReturn=insertString+stringToReturn}}else{if(index2===0)stringToReturn+=insertString}})}else{stringToReturn=spliceString$1(bpString,caretPositionOrRange,0,insertString)}return stringToReturn}__name(adjustBpsToReplaceOrInsert,"adjustBpsToReplaceOrInsert");function calculatePercentGC(bps){return(bps.match(/[cg]/gi)||[]).length/bps.length*100||0}__name(calculatePercentGC,"calculatePercentGC");const calcTmMethods={TABLE_BRESLAUER:"breslauer",TABLE_SUGIMOTO:"sugimoto",TABLE_UNIFIED:"unified",A:-10.8,R:1.987,C:5e-7,Na:.05,calculateTemperature:function(sequence,type,A,R,C,Na){if(typeof type==="undefined"){type=this.TABLE_BRESLAUER}else if(type!=this.TABLE_BRESLAUER&&(type!=this.TABLE_UNIFIED&&type!=this.TABLE_SUGIMOTO)){throw new Error("Invalid table type!")}if(!A){A=this.A}if(!R){R=this.R}if(!C){C=this.C}if(!Na){Na=this.Na}const sequenceLength=sequence.length;if(sequenceLength==0){return 0}const deltaHTable=this.getDeltaHTable(type);const deltaSTable=this.getDeltaSTable(type);const neighbors=[];neighbors.push(this.calculateReps(sequence,"aa"));neighbors.push(this.calculateNumberOfOccurrences(sequence,"at"));neighbors.push(this.calculateNumberOfOccurrences(sequence,"ac"));neighbors.push(this.calculateNumberOfOccurrences(sequence,"ag"));neighbors.push(this.calculateReps(sequence,"tt"));neighbors.push(this.calculateNumberOfOccurrences(sequence,"ta"));neighbors.push(this.calculateNumberOfOccurrences(sequence,"tc"));neighbors.push(this.calculateNumberOfOccurrences(sequence,"tg"));neighbors.push(this.calculateReps(sequence,"cc"));neighbors.push(this.calculateNumberOfOccurrences(sequence,"ca"));neighbors.push(this.calculateNumberOfOccurrences(sequence,"ct"));neighbors.push(this.calculateNumberOfOccurrences(sequence,"cg"));neighbors.push(this.calculateReps(sequence,"gg"));neighbors.push(this.calculateNumberOfOccurrences(sequence,"ga"));neighbors.push(this.calculateNumberOfOccurrences(sequence,"gt"));neighbors.push(this.calculateNumberOfOccurrences(sequence,"gc"));let sumDeltaH=0;let sumDeltaS=0;for(let i=0;i<16;i++){sumDeltaH=sumDeltaH+neighbors[i]*deltaHTable[i];sumDeltaS=sumDeltaS+neighbors[i]*deltaSTable[i]}const temperature=-1e3*sumDeltaH/(A+-sumDeltaS+R*Math.log(C/4))-273.15+16.6*Math.LOG10E*Math.log(Na);if(temperature<0){return 0}return temperature.toFixed(2)},getDeltaHTable:function(type){if(type==this.TABLE_BRESLAUER){return[9.1,8.6,6.5,7.8,9.1,6,5.6,5.8,11,5.8,7.8,11.9,11,5.6,6.5,11.1]}else if(type==this.TABLE_SUGIMOTO){return[8,5.6,6.5,7.8,8,5.6,5.6,5.8,10.9,8.2,6.6,11.8,10.9,6.6,9.4,11.9]}else if(type==this.TABLE_UNIFIED){return[7.9,7.2,8.4,7.8,7.9,7.2,8.2,8.5,8,8.5,7.8,10.6,8,8.2,8.4,9.8]}else{return null}},getDeltaSTable:function(type){if(type==this.TABLE_BRESLAUER){return[24,23.9,17.3,20.8,24,16.9,13.5,12.9,26.6,12.9,20.8,27.8,26.6,13.5,17.3,26.7]}else if(type==this.TABLE_SUGIMOTO){return[21.9,15.2,17.3,20.8,21.9,15.2,13.5,12.9,28.4,25.5,23.5,29,28.4,16.4,25.5,29]}else if(type==this.TABLE_UNIFIED){return[22.2,20.4,22.4,21,22.2,21.3,22.2,22.7,19.9,22.7,21,27.2,19.9,22.2,22.4,24.4]}else{return null}},calculateReps:function(sequence,target){const sequenceLength=sequence.length;if(sequenceLength==0){return 0}let numFound=0;let seqOffset=0;while(true){const foundSeq=sequence.indexOf(target,seqOffset);if(foundSeq==-1){break}seqOffset=foundSeq+1;numFound++;if(seqOffset>sequenceLength){break}}return numFound},calculateNumberOfOccurrences:function(sequence,target){const sequenceLength=sequence.length;if(sequenceLength==0){return 0}const numberFound=sequence.split(target).length-1;return numberFound}};const calculateTm=calcTmMethods.calculateTemperature.bind(calcTmMethods);function convertDnaCaretPositionOrRangeToAA(rangeOrCaret){if(typeof rangeOrCaret==="object"&&rangeOrCaret!==null){return convertDnaRangeToAARange(__spreadProps(__spreadValues({},rangeOrCaret),{locations:rangeOrCaret.locations?rangeOrCaret.locations.map(convertDnaRangeToAARange):void 0}))}else{return convertDnaCaretPositionToAACaretPosition(rangeOrCaret)}}__name(convertDnaCaretPositionOrRangeToAA,"convertDnaCaretPositionOrRangeToAA");function convertDnaCaretPositionToAACaretPosition(caret){return Math.floor(caret/3)}__name(convertDnaCaretPositionToAACaretPosition,"convertDnaCaretPositionToAACaretPosition");function convertDnaRangeToAARange(range){return __spreadProps(__spreadValues({},range),{start:range.start>-1?Math.floor(range.start/3):range.start,end:range.end>-1?Math.floor(range.end-2)/3:range.end})}__name(convertDnaRangeToAARange,"convertDnaRangeToAARange");function rotateBpsToPosition(bps,caretPosition){return arrayRotate(bps.split(""),caretPosition).join("")}__name(rotateBpsToPosition,"rotateBpsToPosition");function arrayRotate(arr,count){count-=arr.length*Math.floor(count/arr.length);arr.push.apply(arr,arr.splice(0,count));return arr}__name(arrayRotate,"arrayRotate");function rotateSequenceDataToPosition(sequenceData,caretPosition,options){const newSequenceData=tidyUpSequenceData(sequenceData,options);newSequenceData.sequence=rotateBpsToPosition(newSequenceData.sequence,caretPosition);modifiableTypes.forEach(annotationType=>{newSequenceData[annotationType]=adjustAnnotationsToRotation(newSequenceData[annotationType],caretPosition,newSequenceData.sequence.length)});return newSequenceData}__name(rotateSequenceDataToPosition,"rotateSequenceDataToPosition");function adjustAnnotationsToRotation(annotationsToBeAdjusted,positionToRotateTo,maxLength){return lodashExports.map(annotationsToBeAdjusted,annotation=>{return __spreadProps(__spreadValues({},adjustRangeToRotation(annotation,positionToRotateTo,maxLength)),{locations:annotation.locations?annotation.locations.map(location=>adjustRangeToRotation(location,positionToRotateTo,maxLength)):void 0})}).filter(range=>!!range)}__name(adjustAnnotationsToRotation,"adjustAnnotationsToRotation");function adjustAnnotationsToInsert(annotationsToBeAdjusted,insertStart,insertLength){return lodashExports.map(annotationsToBeAdjusted,annotation=>{return __spreadValues(__spreadValues({},adjustRangeToInsert(annotation,insertStart,insertLength)),annotation.locations&&{locations:annotation.locations.map(loc=>adjustRangeToInsert(loc,insertStart,insertLength))})})}__name(adjustAnnotationsToInsert,"adjustAnnotationsToInsert");function insertSequenceDataAtPositionOrRange(_sequenceDataToInsert,_existingSequenceData,caretPositionOrRange,options={}){const{maintainOriginSplit}=options;let existingSequenceData=tidyUpSequenceData(_existingSequenceData,options);const sequenceDataToInsert=tidyUpSequenceData(_sequenceDataToInsert,options);let newSequenceData=lodashExports.cloneDeep(existingSequenceData);const insertLength=sequenceDataToInsert.proteinSequence?sequenceDataToInsert.proteinSequence.length*3:sequenceDataToInsert.sequence.length;let caretPosition=caretPositionOrRange;const isInsertSameLengthAsSelection=sequenceDataToInsert.sequence.length===getRangeLength(caretPositionOrRange,existingSequenceData.sequence.length);if(caretPositionOrRange.start>-1&&getRangeLength(caretPositionOrRange,existingSequenceData.sequence.length)===existingSequenceData.sequence.length){existingSequenceData=tidyUpSequenceData(__spreadProps(__spreadValues(__spreadValues({},existingSequenceData),modifiableTypes.reduce((acc,type)=>{return acc[type]=[]},{})),{sequence:"",proteinSequence:"",chromatogramData:void 0}),options);newSequenceData.chromatogramData=void 0}else if(newSequenceData.chromatogramData&&newSequenceData.chromatogramData.baseTraces){if(caretPositionOrRange&&caretPositionOrRange.start>-1){if(caretPositionOrRange.start>caretPositionOrRange.end){newSequenceData.chromatogramData=trimChromatogram({chromatogramData:newSequenceData.chromatogramData,range:{start:caretPositionOrRange.start,end:newSequenceData.sequence.length},justBaseCalls:isInsertSameLengthAsSelection});newSequenceData.chromatogramData=trimChromatogram({chromatogramData:newSequenceData.chromatogramData,range:{start:0,end:caretPositionOrRange.end},justBaseCalls:isInsertSameLengthAsSelection})}else{newSequenceData.chromatogramData=trimChromatogram({chromatogramData:newSequenceData.chromatogramData,range:{start:caretPositionOrRange.start,end:caretPositionOrRange.end},justBaseCalls:isInsertSameLengthAsSelection})}}if(sequenceDataToInsert.sequence){insertIntoChromatogram({chromatogramData:newSequenceData.chromatogramData,caretPosition:caretPositionOrRange.start>-1?caretPositionOrRange.start:caretPositionOrRange,seqToInsert:sequenceDataToInsert.sequence,justBaseCalls:isInsertSameLengthAsSelection})}}newSequenceData.sequence=adjustBpsToReplaceOrInsert(existingSequenceData.sequence,sequenceDataToInsert.sequence,caretPositionOrRange);newSequenceData.size=newSequenceData.sequence.length;newSequenceData.proteinSequence=adjustBpsToReplaceOrInsert(existingSequenceData.proteinSequence,sequenceDataToInsert.proteinSequence,convertDnaCaretPositionOrRangeToAA(caretPositionOrRange));newSequenceData.proteinSize=newSequenceData.proteinSequence.length;modifiableTypes.forEach(annotationType=>{let existingAnnotations=existingSequenceData[annotationType];if(caretPositionOrRange&&caretPositionOrRange.start>-1){const range=caretPositionOrRange;caretPosition=range.start>range.end?0:range.start;existingAnnotations=adjustAnnotationsToDelete(existingAnnotations,range,existingSequenceData.sequence.length)}newSequenceData[annotationType]=[];newSequenceData[annotationType]=newSequenceData[annotationType].concat(adjustAnnotationsToInsert(existingAnnotations,caretPosition,insertLength));newSequenceData[annotationType]=newSequenceData[annotationType].concat(adjustAnnotationsToInsert(sequenceDataToInsert[annotationType],0,caretPosition))});if(maintainOriginSplit&&caretPositionOrRange&&caretPositionOrRange.start>caretPositionOrRange.end){const caretPosToRotateTo=existingSequenceData.sequence.length-caretPositionOrRange.start;return rotateSequenceDataToPosition(newSequenceData,Math.min(caretPosToRotateTo,insertLength))}return newSequenceData}__name(insertSequenceDataAtPositionOrRange,"insertSequenceDataAtPositionOrRange");function adjustAnnotationsToDelete(annotationsToBeAdjusted,range,maxLength){return lodashExports.map(annotationsToBeAdjusted,annotation=>{const newRange=adjustRangeToDeletionOfAnotherRange(annotation,range,maxLength);const newLocations=annotation.locations&&annotation.locations.map(loc=>adjustRangeToDeletionOfAnotherRange(loc,range,maxLength)).filter(range2=>!!range2);if(newLocations&&newLocations.length){return __spreadValues(__spreadProps(__spreadValues({},newRange),{start:newLocations[0].start,end:newLocations[newLocations.length-1].end}),newLocations.length>1&&{locations:newLocations})}else{return newRange}}).filter(range2=>!!range2)}__name(adjustAnnotationsToDelete,"adjustAnnotationsToDelete");function insertIntoChromatogram({chromatogramData,caretPosition,seqToInsert,justBaseCalls}){if(!seqToInsert.length)return;chromatogramData.baseCalls&&chromatogramData.baseCalls.splice(caretPosition,0,...seqToInsert.split(""));if(justBaseCalls){return chromatogramData}let baseTracesToInsert=[];let qualNumsToInsert=[];for(let index2=0;index2<seqToInsert.length;index2++){qualNumsToInsert.push(0);const toPush=[0,0,0,0,0,0,0,0,0,0,0];baseTracesToInsert.push({aTrace:toPush,cTrace:toPush,gTrace:toPush,tTrace:toPush})}chromatogramData.baseTraces&&chromatogramData.baseTraces.splice(caretPosition,0,...baseTracesToInsert);chromatogramData.qualNums&&chromatogramData.qualNums.splice(caretPosition,0,...qualNumsToInsert);return chromatogramData}__name(insertIntoChromatogram,"insertIntoChromatogram");function trimChromatogram({chromatogramData,range:{start,end},justBaseCalls}){["baseCalls",...justBaseCalls?[]:["qualNums","baseTraces","basePos"]].forEach(type=>{chromatogramData[type]&&chromatogramData[type].splice(start,end-start+1)});return chromatogramData}__name(trimChromatogram,"trimChromatogram");function deleteSequenceDataAtRange(sequenceData,range){return insertSequenceDataAtPositionOrRange({},sequenceData,range)}__name(deleteSequenceDataAtRange,"deleteSequenceDataAtRange");function doesEnzymeChopOutsideOfRecognitionSite(enzyme){if(enzyme.topSnipOffset>enzyme.site.length||enzyme.bottomSnipOffset>enzyme.site.length){return true}else{return false}}__name(doesEnzymeChopOutsideOfRecognitionSite,"doesEnzymeChopOutsideOfRecognitionSite");const 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aliasedEnzymesByName={};aliasedEnzymes.forEach(enz=>{enz.aliases.forEach(name=>{aliasedEnzymesByName[name.toLowerCase()]=__spreadProps(__spreadValues({},enz),{name})})});const defaultEnzymes=["aari","aatii","aaui","accebi","acci","accii","acciii","acsi","afai","aflii","alui","aor13hi","aor51hi","apai","apali","asci","asisi","asp35hi","asp713i","aspmi","atsi","atu1i","atu1ii","avrbi","avrii","bali","bamhi","banii","bari","baui","bbvbi","bcni","bcoki","bdii","bgli","bglii","blni","bme216i","bmet110i","bmgt120i","bmui","bnai","bpu1102i","bpuai","bpub5i","bsai","bsavi","bseri","bsgi","bshhi","bsiwi","bsmbi","bsmfi","bsofi","bsp105i","bsp1286i","bsp139i","bsp1407i","bsp4009i","bsp70i","bsp71i","bspa2i","bspci","bspfni","bspt104i","bspt107i","bsrfi","bsshii","bst1107i","bstb7si","bsthi","bstiz316i","bstli","bstpi","bstri","bstxi","bsu1532i","bsu8565i","bsu90i","btgai","btsci","btsi","bvei","ccini","ccop95i","ceqi","cfr10i","cfr45i","cfr47i","cfr6i","cjuii","clai","cpaai","cpoi","cspai","cspci","ddei","dpni","drai","dsai","dsavi","eaei","eagi","eam1105i","ecidi","ecl37i","eco211i","eco240i","eco241i","eco246i","eco247i","eco52i","eco68i","eco81i","eco93i","ecoicri","ecoo109i","ecoo65i","ecopi","ecoprri","ecori","ecorv","ecot14i","ecot22i","ecoviii","ehei","esphk22i","fbai","fdiii","foki","fsei","haeii","haeiii","hapii","hgiai","hgibi","hhai","hin1i","hincii","hindiii","hinfi","hpai","hpyf13iii","hpyf19ii","hpyf21i","hpyf28i","hpyf29i","hpyf36i","hpyf62i","hpyf65i","hpyii","koyi","kpni","m.bbu297i","m.pmudam","maek81i","mboi","mboii","mfli","mizi","mlui","mph1103ii","msei","msii","mspi","mthai","muni","naei","ncoi","ndai","ndei","nflaii","ngbi","ngobviii","ngodviii","ngoeii","ngotii","nhei","nlaiv","noci","noti","novii","nrui","nsbi","nsici","nsp29132i","paci","pae17ki","pca17ai","pfaaiii","pfl16i","ple214i","pmaci","pmei","pru2i","psb9879i","pshai","pshbi","psp1406i","psp31i","psp33i","psp5i","psti","psuni","pvui","pvuii","ral8i","rsplki","saci","sacii","sali","sapi","sau3ai","sauni","sbai","sbfi","scai","sfii","sflhk115731i","slu1777i","smai","smii","snabi","spei","sphi","srfi","srl61di","sse8387i","ssp2i","sspi","stui","suii","swai","taqi","tauii","tsci","tth111i","tthhb8i","uba1093i","uba1095i","uba1122i","uba1160i","uba1229i","uba1371i","uba1380i","uba1403i","uba1415i","uba1437i","uba1439i","uba1440i","uba36i","uba41i","uba42i","uba89i","uban13i","van91i","vcho66i","vpak11bi","vpakutji","xbai","xcyi","xhoi","xmai","xmli","xphi","xspi"];const defaultEnzymesByName={};defaultEnzymes.forEach(name=>{defaultEnzymesByName[name]=aliasedEnzymesByName[name]});function generateAnnotations(numberOfAnnotationsToGenerate,start,end,maxLength){const result={};for(let i=0;i<numberOfAnnotationsToGenerate;i++){const annotation=generateAnnotation(start,end,maxLength);result[annotation.id]=annotation}return result}__name(generateAnnotations,"generateAnnotations");function generateAnnotation(start,end,maxLength){const range=generateRandomRange(start,end,maxLength);return __spreadProps(__spreadValues({},range),{name:getRandomInt(0,1e5).toString(),type:"misc_feature",id:bsonObjectId().str,forward:Math.random()>.5,notes:{}})}__name(generateAnnotation,"generateAnnotation");function getRandomInt(min,max){return Math.floor(Math.random()*(max-min))+min}__name(getRandomInt,"getRandomInt");function generateSequenceData({isProtein,sequenceLength=1e3,numFeatures,numParts,numPrimers,numTranslations}={}){const proteinSequence=isProtein&&generateSequence(sequenceLength,true);const sequence=!isProtein&&generateSequence(sequenceLength);return{circular:isProtein?false:Math.random()>.5,name:"p-"+Math.floor(Math.random*100),description:"",isProtein,sequence,proteinSequence,translations:isProtein?void 0:generateAnnotations(numTranslations||5,0,sequenceLength-1,sequenceLength/3),features:generateAnnotations(numFeatures||10,0,sequenceLength-1,sequenceLength/3),primers:isProtein?void 0:generateAnnotations(numPrimers||10,0,sequenceLength-1,50),parts:generateAnnotations(numParts||10,0,sequenceLength-1,sequenceLength/3)}}__name(generateSequenceData,"generateSequenceData");function generateSequence(m=9,isProtein){let s="";const r=isProtein?"":"gatc";for(let i=0;i<m;i++){s+=r.charAt(Math.floor(Math.random()*r.length))}return s}__name(generateSequence,"generateSequence");function findNearestRangeOfSequenceOverlapToPosition(sequenceToSearch,overlapSequence,positionStart,isLinear){if(!positionStart)positionStart=0;if(sequenceToSearch.length<overlapSequence.length){return null}const regex=new RegExp(overlapSequence,"ig");let result;let index2;let distance=Infinity;while(result=regex.exec(sequenceToSearch+(isLinear?"":sequenceToSearch))){if(result.index>sequenceToSearch.length)break;let newDistance=Math.abs(result.index-positionStart);newDistance=isLinear?newDistance:Math.min(newDistance,Math.abs(newDistance-sequenceToSearch.length));if(newDistance>distance){break}index2=result.index;distance=newDistance}return normalizeRange({start:index2,end:index2+overlapSequence.length-1},sequenceToSearch.length)}__name(findNearestRangeOfSequenceOverlapToPosition,"findNearestRangeOfSequenceOverlapToPosition");function getOrfsFromSequence(options){let sequence=options.sequence;const minimumOrfSize=options.minimumOrfSize;const forward=options.forward;const circular=options.circular;const useAdditionalOrfStartCodons=options.useAdditionalOrfStartCodons;const originalSequenceLength=sequence.length;if(!forward){sequence=getReverseComplementSequenceString(sequence)}if(circular){sequence+=sequence}const re=useAdditionalOrfStartCodons?/(?=((?:A[TU]G|G[TU]G|C[TU]G)(?:.{3})*?(?:[TU]AG|[TU]AA|[TU]GA)))/gi:/(?=((?:A[TU]G)(?:.{3})*?(?:[TU]AG|[TU]AA|[TU]GA)))/gi;let m;const orfRanges=[];while((m=re.exec(sequence))!==null){if(m.index===re.lastIndex){re.lastIndex++}const orfLength=m[1].length;if(orfLength>=minimumOrfSize){const start=m.index;let end=orfLength+start-1;if(end>=originalSequenceLength){end-=originalSequenceLength}if(start<originalSequenceLength){orfRanges.push({start,end,length:m[1].length,internalStartCodonIndices:[],frame:start%3,forward,annotationTypePlural:"orfs",isOrf:true,id:bsonObjectId().str})}}}const orfEnds={};orfRanges.forEach((orf,index2)=>{const indexOfAlreadyExistingOrf=orfEnds[orf.end];if(typeof indexOfAlreadyExistingOrf!=="undefined"){let internalOrf=orf;let containingOrf=orfRanges[indexOfAlreadyExistingOrf];if(containingOrf.length<internalOrf.length){internalOrf=orfRanges[indexOfAlreadyExistingOrf];containingOrf=orf;orfEnds[orf.end]=index2}const internalStartCodonIndex=forward?internalOrf.start:originalSequenceLength-internalOrf.start-1;containingOrf.internalStartCodonIndices=[...containingOrf.internalStartCodonIndices,...internalOrf.internalStartCodonIndices,internalStartCodonIndex];internalOrf.remove=true}else{orfEnds[orf.end]=index2;if(!forward){const endHolder=orf.end;orf.end=originalSequenceLength-orf.start-1;orf.start=originalSequenceLength-endHolder-1}}});const nonDuplicatedOrfRanges=orfRanges.filter(orf=>{if(!orf.remove){return true}return false});return nonDuplicatedOrfRanges}__name(getOrfsFromSequence,"getOrfsFromSequence");function findOrfsInPlasmid(sequence,circular,minimumOrfSize,useAdditionalOrfStartCodons){const forwardOrfs=getOrfsFromSequence({sequence,minimumOrfSize,forward:true,circular,useAdditionalOrfStartCodons});const reverseOrfs=getOrfsFromSequence({sequence,minimumOrfSize,forward:false,circular,useAdditionalOrfStartCodons});return forwardOrfs.concat(reverseOrfs)}__name(findOrfsInPlasmid,"findOrfsInPlasmid");var matchOperatorsRe=/[|\\{}()[\]^$+*?.]/g;var escapeStringRegexp=__name(function(str){if(typeof str!=="string"){throw new TypeError("Expected a string")}return str.replace(matchOperatorsRe,"\\$&")},"escapeStringRegexp");const escapeStringRegexp$1=getDefaultExportFromCjs(escapeStringRegexp);function getAminoAcidStringFromSequenceString(sequenceString){const aminoAcidsPerBase=getAminoAcidDataForEachBaseOfDna(sequenceString,true);const aaArray=[];let aaString="";aminoAcidsPerBase.forEach(aa=>{if(!aa.fullCodon){return}aaArray[aa.aminoAcidIndex]=aa.aminoAcid.value});aaString=aaArray.join("");return aaString}__name(getAminoAcidStringFromSequenceString,"getAminoAcidStringFromSequenceString");function findSequenceMatches(sequence,searchString,options={}){let matches=findSequenceMatchesTopStrand(sequence,searchString,options);const{searchReverseStrand}=options;if(searchReverseStrand){const sequenceLength=sequence.length;let reverseSeq;reverseSeq=getReverseComplementSequenceString(sequence);const reverseMatches=findSequenceMatchesTopStrand(reverseSeq,searchString,options);const flippedReverseMatches=reverseMatches.map(range=>{return __spreadProps(__spreadValues({},flipRelativeRange(range,{start:0,end:sequenceLength-1},sequenceLength)),{bottomStrand:true})});matches=[...matches,...flippedReverseMatches]}return matches}__name(findSequenceMatches,"findSequenceMatches");function findSequenceMatchesTopStrand(sequence,searchString,options={}){const{isCircular,isAmbiguous,isProteinSequence,isProteinSearch}=options;let searchStringToUse=escapeStringRegexp$1(searchString);if(isAmbiguous){if(isProteinSearch||isProteinSequence){searchStringToUse=convertAmbiguousStringToRegex(searchStringToUse,true)}else{searchStringToUse=convertAmbiguousStringToRegex(searchStringToUse)}}if(!searchStringToUse)return[];let sequenceToUse=sequence;if(isCircular){sequenceToUse=sequenceToUse+sequenceToUse}let sequencesToCheck=[{seqToCheck:sequenceToUse,offset:0}];if(isProteinSearch){sequencesToCheck=[{seqToCheck:getAminoAcidStringFromSequenceString(sequenceToUse),offset:0},{seqToCheck:getAminoAcidStringFromSequenceString(sequenceToUse.substr(1)),offset:1},{seqToCheck:getAminoAcidStringFromSequenceString(sequenceToUse.substr(2)),offset:2}]}let ranges=[];sequencesToCheck.forEach(({seqToCheck,offset})=>{const reg=new RegExp(searchStringToUse,"ig");let match;let range;while((match=reg.exec(seqToCheck))!==null){range={start:match.index,end:match.index+searchString.length-1};if(isProteinSearch){range.start=range.start*3+offset;range.end=range.end*3+2+offset}ranges.push(modulateRangeBySequenceLength(range,sequence.length));reg.lastIndex=match.index+1}});return lodashExports.uniqBy(ranges,e=>{return e.start+"-"+e.end})}__name(findSequenceMatchesTopStrand,"findSequenceMatchesTopStrand");function convertAmbiguousStringToRegex(string,isProtein){return lodashExports.reduce(string,(acc,char)=>{const value=isProtein?extended_protein_values[char.toUpperCase()]:ambiguous_dna_values[char.toUpperCase()];if(!value)return acc;if(value.length===1){acc+=value}else{acc+=`[${value}]`}return acc},"")}__name(convertAmbiguousStringToRegex,"convertAmbiguousStringToRegex");function getCodonRangeForAASliver(aminoAcidPositionInSequence,aminoAcidSliver,AARepresentationOfTranslation,relativeAAPositionInTranslation){const AASliverOneBefore=AARepresentationOfTranslation[relativeAAPositionInTranslation-1];if(AASliverOneBefore&&AASliverOneBefore.aminoAcidIndex===aminoAcidSliver.aminoAcidIndex){const AASliverTwoBefore=AARepresentationOfTranslation[relativeAAPositionInTranslation-2];if(AASliverTwoBefore&&AASliverTwoBefore.aminoAcidIndex===aminoAcidSliver.aminoAcidIndex){return{start:aminoAcidPositionInSequence-2,end:aminoAcidPositionInSequence}}else{if(aminoAcidSliver.fullCodon===true){return{start:aminoAcidPositionInSequence-1,end:aminoAcidPositionInSequence+1}}else{return{start:aminoAcidPositionInSequence-1,end:aminoAcidPositionInSequence}}}}else{if(aminoAcidSliver.fullCodon===true){return{start:aminoAcidPositionInSequence,end:aminoAcidPositionInSequence+2}}else{const AASliverOneAhead=AARepresentationOfTranslation[relativeAAPositionInTranslation-2];if(AASliverOneAhead&&AASliverOneAhead.aminoAcidIndex===aminoAcidSliver.aminoAcidIndex){return{start:aminoAcidPositionInSequence,end:aminoAcidPositionInSequence+1}}else{return{start:aminoAcidPositionInSequence,end:aminoAcidPositionInSequence+1}}}}}__name(getCodonRangeForAASliver,"getCodonRangeForAASliver");function getComplementAminoAcidStringFromSequenceString(sequenceString){const aaString=getAminoAcidStringFromSequenceString(sequenceString);return aaString.split("").reverse().join("")}__name(getComplementAminoAcidStringFromSequenceString,"getComplementAminoAcidStringFromSequenceString");function getComplementSequenceString(sequence){let complementSeqString="";for(let i=0;i<sequence.length;i++){let complementChar=DNAComplementMap[sequence[i]];if(!complementChar){complementChar=sequence[i]}complementSeqString+=complementChar}return complementSeqString}__name(getComplementSequenceString,"getComplementSequenceString");function getSequenceDataBetweenRange(seqData,range,options={}){if(!range)return seqData;const{exclude={},excludePartial={}}=options;const seqDataToUse=tidyUpSequenceData(seqData,options);annotationTypes.forEach(type=>{delete seqDataToUse[`filtered${lodashExports.startCase(type)}`]});const seqDataToReturn=lodashExports.extend({},seqDataToUse,{circular:seqDataToUse.sequence.length===getRangeLength(range,seqData.sequence.length)?seqDataToUse.circular:false,sequence:getSequenceWithinRange(range,seqDataToUse.sequence),proteinSequence:getSequenceWithinRange(convertDnaCaretPositionOrRangeToAA(range),seqDataToUse.proteinSequence)},annotationTypes.reduce((acc,type)=>{if(exclude[type]){acc[type]=[];return acc}acc[type]=getAnnotationsBetweenRange(seqDataToUse[type],range,seqDataToUse.sequence.length,excludePartial[type]);return acc},{}));if(range.overlapsSelf){const extendedSeqData=insertSequenceDataAtPositionOrRange({sequence:seqDataToReturn.sequence},seqDataToUse,range.start);const toRet=getSequenceDataBetweenRange(extendedSeqData,{start:range.end+1,end:range.end},options);annotationTypes.forEach(type=>{lodashExports.forEach(toRet[type],ann=>{if(ann.overlapsSelf&&ann.start===0&&getRangeLength(ann,seqDataToUse.sequence.length)===getRangeLength(range,seqDataToUse.sequence.length)){ann.overlapsSelf=false;ann.end=toRet.sequence.length-1}})});return tidyUpSequenceData(toRet,options)}return tidyUpSequenceData(seqDataToReturn,options)}__name(getSequenceDataBetweenRange,"getSequenceDataBetweenRange");function getAnnotationsBetweenRange(annotationsToBeAdjusted,range,maxLength,shouldExcludePartial){return lodashExports.flatMap(annotationsToBeAdjusted,annotation=>{if(annotation.locations&&annotation.locations.length){annotation.locations=getAnnotationsBetweenRange(annotation.locations,range,maxLength,shouldExcludePartial)}const overlaps=getZeroedRangeOverlaps(annotation,range,maxLength).map(overlap=>{return lodashExports.extend({},annotation,overlap)});if(shouldExcludePartial){if(overlaps.length>1)return[];if(overlaps[0]){if(getRangeLength(overlaps[0],maxLength)!==getRangeLength(annotation,maxLength)){return[]}}}return overlaps}).map(annotation=>{if(annotation.locations&&annotation.locations.length){annotation.start=annotation.locations[0].start;annotation.end=annotation.locations[annotation.locations.length-1].end;if(annotation.locations.length===1)delete annotation.locations}return annotation})}__name(getAnnotationsBetweenRange,"getAnnotationsBetweenRange");function getComplementSequenceAndAnnotations(pSeqObj,options={}){const seqObj=tidyUpSequenceData(getSequenceDataBetweenRange(pSeqObj,options.range),options);const newSeqObj=Object.assign({},seqObj,{sequence:getComplementSequenceString(seqObj.sequence)});return tidyUpSequenceData(newSeqObj,options)}__name(getComplementSequenceAndAnnotations,"getComplementSequenceAndAnnotations");function getCutsiteType(restrictionEnzyme){const{topSnipOffset,bottomSnipOffset}=restrictionEnzyme;if(topSnipOffset===bottomSnipOffset){return"blunt"}else if(topSnipOffset<bottomSnipOffset){return"5' overhang"}else{return"3' overhang"}}__name(getCutsiteType,"getCutsiteType");function getInsertBetweenVals(caretPosition,selectionLayer,sequenceLength){if(selectionLayer.start>-1){return[normalizePositionByRangeLength1Based(selectionLayer.start,sequenceLength),normalizePositionByRangeLength1Based(selectionLayer.end+2,sequenceLength)]}else if(caretPosition>-1){return[normalizePositionByRangeLength1Based(caretPosition,sequenceLength),normalizePositionByRangeLength1Based(caretPosition+1,sequenceLength)]}else{return[sequenceLength,1]}}__name(getInsertBetweenVals,"getInsertBetweenVals");function getLeftAndRightOfSequenceInRangeGivenPosition(range,position,sequence){let result={leftHandSide:"",rightHandSide:""};if(isPositionWithinRange(position,range)){result.leftHandSide=getSequenceWithinRange({start:range.start,end:normalizePositionByRangeLength(position-1,sequence.length)},sequence);result.rightHandSide=getSequenceWithinRange({start:position,end:range.end},sequence)}else{if(isPositionCloserToRangeStartThanRangeEnd(position,range,sequence.length)){result.rightHandSide=getSequenceWithinRange(range,sequence)}else{result.leftHandSide=getSequenceWithinRange(range,sequence)}}return result}__name(getLeftAndRightOfSequenceInRangeGivenPosition,"getLeftAndRightOfSequenceInRangeGivenPosition");function getOverlapBetweenTwoSequences(sequenceToFind,sequenceToSearchIn,options){sequenceToSearchIn=sequenceToSearchIn.toLowerCase();sequenceToFind=sequenceToFind.toLowerCase();const lengthenedSeqToSearch=sequenceToSearchIn+sequenceToSearchIn;const index2=lengthenedSeqToSearch.indexOf(sequenceToFind);if(index2>-1){return{start:index2,end:modulatePositionByRange(index2+sequenceToFind.length-1,{start:0,end:sequenceToSearchIn.length-1})}}else{return null}}__name(getOverlapBetweenTwoSequences,"getOverlapBetweenTwoSequences");function getPossiblePartsFromSequenceAndEnzyme(seqData,restrictionEnzymes){restrictionEnzymes=restrictionEnzymes.length?restrictionEnzymes:[restrictionEnzymes];let bps=seqData.sequence;let seqLen=bps.length;let circular=seqData.circular;let cutsites=[];restrictionEnzymes.forEach(enzyme=>{let newCutsites=cutSequenceByRestrictionEnzyme(bps,circular,enzyme);cutsites=cutsites.concat(newCutsites)});let parts=[];if(cutsites.length<1){return parts}else if(cutsites.length===1){parts.push(getPartBetweenEnzymesWithInclusiveOverhangs(cutsites[0],cutsites[0],seqLen));return parts}else{let pairs=pairwise(cutsites);pairs.forEach(pair=>{let cut1=pair[0];let cut2=pair[1];let part1=getPartBetweenEnzymesWithInclusiveOverhangs(cut1,cut2,seqLen);let part2=getPartBetweenEnzymesWithInclusiveOverhangs(cut2,cut1,seqLen);if(circular||!(part1.start>part1.end)){parts.push(part1)}if(circular||!(part2.start>part2.end)){parts.push(part2)}});return parts}}__name(getPossiblePartsFromSequenceAndEnzyme,"getPossiblePartsFromSequenceAndEnzyme");function getPartBetweenEnzymesWithInclusiveOverhangs(cut1,cut2,seqLen){let firstCutOffset=getEnzymeRelativeOffset(cut1.restrictionEnzyme);let secondCutOffset=getEnzymeRelativeOffset(cut2.restrictionEnzyme);let start=cut1.topSnipBeforeBottom?cut1.topSnipPosition:cut1.bottomSnipPosition;let end=normalizePositionByRangeLength((cut2.topSnipBeforeBottom?cut2.bottomSnipPosition:cut2.topSnipPosition)-1,seqLen);return{start,start1Based:start+1,end,end1Based:end+1,firstCut:cut1,firstCutOffset,firstCutOverhang:cut1.overhangBps,firstCutOverhangTop:firstCutOffset>0?cut1.overhangBps:"",firstCutOverhangBottom:firstCutOffset<0?getComplementSequenceString(cut1.overhangBps):"",secondCut:cut2,secondCutOffset,secondCutOverhang:cut2.overhangBps,secondCutOverhangTop:secondCutOffset<0?cut2.overhangBps:"",secondCutOverhangBottom:secondCutOffset>0?getComplementSequenceString(cut2.overhangBps):""}}__name(getPartBetweenEnzymesWithInclusiveOverhangs,"getPartBetweenEnzymesWithInclusiveOverhangs");function getEnzymeRelativeOffset(enzyme){return enzyme.bottomSnipOffset-enzyme.topSnipOffset}__name(getEnzymeRelativeOffset,"getEnzymeRelativeOffset");function pairwise(list){if(list.length<2){return[]}let first=list[0],rest=list.slice(1),pairs=rest.map(x=>{return[first,x]});return pairs.concat(pairwise(rest))}__name(pairwise,"pairwise");function getReverseAminoAcidStringFromSequenceString(sequenceString){const aminoAcidsPerBase=getAminoAcidDataForEachBaseOfDna(sequenceString,false);const aaArray=[];let aaString="";aminoAcidsPerBase.forEach(aa=>{if(!aa.fullCodon){return}aaArray[aa.aminoAcidIndex]=aa.aminoAcid.value});aaString=aaArray.join("");return aaString}__name(getReverseAminoAcidStringFromSequenceString,"getReverseAminoAcidStringFromSequenceString");function getReverseComplementAminoAcidStringFromSequenceString(sequenceString){return getAminoAcidStringFromSequenceString(getReverseComplementSequenceString(sequenceString))}__name(getReverseComplementAminoAcidStringFromSequenceString,"getReverseComplementAminoAcidStringFromSequenceString");function getReverseComplementAnnotation(annotation,sequenceLength){return Object.assign({},annotation,{start:sequenceLength-(annotation.end+1),end:sequenceLength-(annotation.start+1),forward:!annotation.forward,strand:annotation.strand===1?-1:1})}__name(getReverseComplementAnnotation,"getReverseComplementAnnotation");function getReverseComplementSequenceAndAnnoations(pSeqObj,options={}){const seqObj=tidyUpSequenceData(getSequenceDataBetweenRange(pSeqObj,options.range),options);const newSeqObj=Object.assign({},seqObj,{sequence:getReverseComplementSequenceString(seqObj.sequence)},annotationTypes.reduce((acc,type)=>{if(seqObj[type]){acc[type]=lodashExports.map(seqObj[type],annotation=>{return getReverseComplementAnnotation(annotation,seqObj.sequence.length)})}return acc},{}));return tidyUpSequenceData(newSeqObj,options)}__name(getReverseComplementSequenceAndAnnoations,"getReverseComplementSequenceAndAnnoations");function getReverseSequenceString(sequence){let reverseSequenceString="";for(let i=sequence.length-1;i>=0;i--){let revChar=sequence[i];if(!revChar){revChar=sequence[i]}reverseSequenceString+=revChar}return reverseSequenceString}__name(getReverseSequenceString,"getReverseSequenceString");function guessIfSequenceIsDnaAndNotProtein(seq,options={}){const{threshold=.9,loose}=options;const dnaLetters=options.dnaLetters||loose?[...ambiguous_dna_letters.split(""),"U"]:["G","A","T","C","U"];const dnaLetterMap=dnaLetters.reduce((acc,letter)=>{acc[letter.toUpperCase()]=true;return acc},{});let count=0;if(!seq||!seq.length)return true;for(let index2=0;index2<seq.length;index2++){const letter=seq[index2];if(dnaLetterMap[letter.toUpperCase()]){count=count+1}}if(count/seq.length>threshold){return true}return false}__name(guessIfSequenceIsDnaAndNotProtein,"guessIfSequenceIsDnaAndNotProtein");function mapAnnotationsToRows(annotations,sequenceLength,bpsPerRow,{splitForwardReverse}={}){const annotationsToRowsMap={};const yOffsetLevelMap={};const wrappedAnnotations={};lodashExports.each(annotations,annotation=>{const containsLocations=!!(annotation.locations&&annotation.locations.length);if(annotation.overlapsSelf){if(!wrappedAnnotations[annotation.id]){mapAnnotationToRows({wrappedAnnotations,annotation:{start:0,end:sequenceLength-1,id:`__tempAnnRemoveMe__${annotation.id}`},sequenceLength,bpsPerRow,annotationsToRowsMap,yOffsetLevelMap,containsLocations,splitForwardReverse});wrappedAnnotations[annotation.id]=true}}mapAnnotationToRows({wrappedAnnotations,annotation,sequenceLength,bpsPerRow,annotationsToRowsMap,yOffsetLevelMap,containsLocations,splitForwardReverse});if(containsLocations){annotation.locations.forEach(location=>{mapAnnotationToRows({wrappedAnnotations,annotation,sequenceLength,bpsPerRow,annotationsToRowsMap,yOffsetLevelMap,location,splitForwardReverse})})}});lodashExports.forEach(annotationsToRowsMap,(annotationsForRow,i)=>{annotationsToRowsMap[i]=lodashExports.filter(annotationsForRow,ann=>!lodashExports.startsWith(ann.id,"__tempAnnRemoveMe__"))});return annotationsToRowsMap}__name(mapAnnotationsToRows,"mapAnnotationsToRows");function mapAnnotationToRows({wrappedAnnotations,annotation,sequenceLength,bpsPerRow,annotationsToRowsMap,yOffsetLevelMap,location,containsLocations,splitForwardReverse}){const ranges=splitRangeIntoTwoPartsIfItIsCircular(location||annotation,sequenceLength);ranges.forEach((range,index2)=>{const startingRow=Math.floor(range.start/bpsPerRow);const endingRow=Math.floor(range.end/bpsPerRow);for(let rowNumber=startingRow;rowNumber<=endingRow;rowNumber++){if(!annotationsToRowsMap[rowNumber]){annotationsToRowsMap[rowNumber]=[]}const key=splitForwardReverse?annotation.forward?rowNumber+"_forward":rowNumber+"_reverse":rowNumber;const annotationsForRow=annotationsToRowsMap[rowNumber];if(!yOffsetLevelMap[key]){yOffsetLevelMap[key]=[]}let yOffset;const yOffsetsForRow=yOffsetLevelMap[key];const start=rowNumber===startingRow?range.start:rowNumber*bpsPerRow;const end=rowNumber===endingRow?range.end:rowNumber*bpsPerRow+bpsPerRow-1;if(annotation.overlapsSelf){annotationsForRow.forEach(ann=>{if(ann.id===`__tempAnnRemoveMe__${annotation.id}`){yOffset=ann.yOffset}})}else{if(location){annotationsForRow.forEach(ann=>{if(ann.id===annotation.id){yOffset=ann.yOffset}})}else{if(index2>0&&annotationsForRow.length&&annotationsForRow[annotationsForRow.length-1].annotation===annotation){yOffset=annotationsForRow[annotationsForRow.length-1].yOffset}else{yOffset=getYOffsetForPotentiallyCircularRange(annotation,yOffsetsForRow)}if(!yOffsetsForRow[yOffset])yOffsetsForRow[yOffset]=[];yOffsetsForRow[yOffset].push({start,end})}}annotationsForRow.push(__spreadProps(__spreadValues(__spreadValues({id:annotation.id,annotation,start,end},containsLocations&&{containsLocations}),location&&{isJoinedLocation:!!location}),{yOffset,enclosingRangeType:range.type}))}})}__name(mapAnnotationToRows,"mapAnnotationToRows");function prepareCircularViewData(sequenceData){const clonedSeqData=lodashExports.cloneDeep(sequenceData);annotationTypes.forEach(annotationType=>{if(annotationType!=="cutsites"){const maxYOffset=getYOffsetsForPotentiallyCircularRanges(clonedSeqData[annotationType]).maxYOffset;clonedSeqData[annotationType].maxYOffset=maxYOffset}});return clonedSeqData}__name(prepareCircularViewData,"prepareCircularViewData");function prepareRowData(sequenceData,bpsPerRow){const sequenceLength=sequenceData.sequence.length;const totalRows=Math.ceil(sequenceLength/bpsPerRow)||1;const rows=[];const rowMap={};annotationTypes.forEach(type=>{rowMap[type]=mapAnnotationsToRows(sequenceData[type],sequenceLength,bpsPerRow,{splitForwardReverse:type==="primers"})});for(let rowNumber=0;rowNumber<totalRows;rowNumber++){const row={};row.rowNumber=rowNumber;row.start=rowNumber*bpsPerRow;row.end=(rowNumber+1)*bpsPerRow-1<sequenceLength?(rowNumber+1)*bpsPerRow-1:sequenceLength-1;if(row.end<0){row.end=0}annotationTypes.forEach(type=>{row[type]=rowMap[type][rowNumber]||[]});row.sequence=sequenceData.sequence.slice(row.start,row.end+1);rows[rowNumber]=row}return rows}__name(prepareRowData,"prepareRowData");function condensePairwiseAlignmentDifferences(referenceSeq,alignedSeq){let overviewMinimapTrack=[];const referenceSeqSplit=referenceSeq.toLowerCase().split("");const alignedSeqSplit=alignedSeq.toLowerCase().split("");const seqLength=alignedSeq.length;const alignedSeqWithoutLeadingDashes=alignedSeq.replace(/^-+/g,"");const alignedSeqWithoutTrailingDashes=alignedSeq.replace(/-+$/g,"");const startIndex=seqLength-alignedSeqWithoutLeadingDashes.length;const endIndex=seqLength-(seqLength-alignedSeqWithoutTrailingDashes.length);for(let i=0;i<referenceSeqSplit.length;i++){if(i<startIndex||i>=endIndex){overviewMinimapTrack.push("W")}else if(referenceSeqSplit[i]===alignedSeqSplit[i]&&referenceSeqSplit[i]!=="-"&&alignedSeqSplit[i]!=="-"){overviewMinimapTrack.push("G")}else if(referenceSeqSplit[i]!==alignedSeqSplit[i]&&referenceSeqSplit[i]!=="-"&&alignedSeqSplit[i]!=="-"){overviewMinimapTrack.push("R")}else if(alignedSeqSplit[i]==="-"){overviewMinimapTrack.push("R")}else if(referenceSeqSplit[i]==="-"&&referenceSeqSplit[i-1]!=="-"&&i!==referenceSeqSplit.length-1&&referenceSeqSplit[i+1]==="-"){overviewMinimapTrack.push("R")}else if(referenceSeqSplit[i]==="-"&&referenceSeqSplit[i-1]!=="-"&&i!==referenceSeqSplit.length-1&&referenceSeqSplit[i+1]!=="-"){overviewMinimapTrack.push("R");i++}else if(i===referenceSeqSplit.length-1&&referenceSeqSplit[i]==="-"&&referenceSeqSplit[i-1]==="-"){overviewMinimapTrack.splice(-2,1)}else if(i===referenceSeqSplit.length-1&&referenceSeqSplit[i]==="-"&&referenceSeqSplit[i-1]!=="-"){overviewMinimapTrack.pop();overviewMinimapTrack.push("R")}else if(referenceSeqSplit[i]==="-"&&referenceSeqSplit[i-1]==="-"&&referenceSeqSplit[i+1]!=="-"){i++}else if(referenceSeqSplit[i]==="-"&&referenceSeqSplit[i-1]==="-");else{console.error("should not reach this step!")}}return overviewMinimapTrack.join("")}__name(condensePairwiseAlignmentDifferences,"condensePairwiseAlignmentDifferences");function addGapsToSeqReads(refSeq,seqReads){for(let i=0;i<seqReads.length;i++){if(seqReads[i].cigar===null){seqReads.splice(i,1)}}const refSeqWithGaps=insertGapsIntoRefSeq(refSeq.sequence,seqReads);const seqReadsWithGaps=[{name:refSeq.name,sequence:refSeqWithGaps.toUpperCase()}];seqReads.forEach(seqRead=>{const allInsertionsInSeqReads=[];seqReads.forEach(seqRead2=>{const splitSeqRead=seqRead2.cigar.match(/([0-9]*[SMDI])/g);let adjustedSeqReadPos2=lodashExports.cloneDeep(seqRead2.pos);if(splitSeqRead[0].slice(-1)==="S"){const numOfBeginningSoftClipped=splitSeqRead[0].slice(0,-1);adjustedSeqReadPos2=seqRead2.pos-numOfBeginningSoftClipped}for(let componentI=0;componentI<splitSeqRead.length;componentI++){if(splitSeqRead[componentI].slice(-1)==="I"){let bpPosOfInsertion=adjustedSeqReadPos2;const numberOfInsertions=Number(splitSeqRead[componentI].slice(0,-1));for(let i=0;i<componentI;i++){if(splitSeqRead[i].slice(-1)!=="I"){const previousComponentNumber=Number(splitSeqRead[i].slice(0,-1));bpPosOfInsertion+=previousComponentNumber}}const insertionInfo={bpPos:bpPosOfInsertion,number:numberOfInsertions};allInsertionsInSeqReads.push(insertionInfo)}}});const splitSeqReadChunk=seqRead.cigar.match(/([0-9]*[SMDI])/g);let adjustedSeqReadPos=lodashExports.cloneDeep(seqRead.pos);if(splitSeqReadChunk[0].slice(-1)==="S"){const numOfBeginningSoftClipped=splitSeqReadChunk[0].slice(0,-1);adjustedSeqReadPos=seqRead.pos-numOfBeginningSoftClipped}let eachSeqReadWithGaps=seqRead.seq.split("");if(adjustedSeqReadPos>0){eachSeqReadWithGaps.unshift("-".repeat(adjustedSeqReadPos-1))}eachSeqReadWithGaps=eachSeqReadWithGaps.join("").split("");const ownDeletions=[];for(let componentI=0;componentI<splitSeqReadChunk.length;componentI++){if(splitSeqReadChunk[componentI].slice(-1)==="D"){let bpPosOfDeletion=adjustedSeqReadPos;const numberOfDeletions=Number(splitSeqReadChunk[componentI].slice(0,-1));for(let i=0;i<componentI;i++){const previousComponentNumber=Number(splitSeqReadChunk[i].slice(0,-1));bpPosOfDeletion+=previousComponentNumber}const deletionInfo={bpPos:bpPosOfDeletion,number:numberOfDeletions};ownDeletions.push(deletionInfo)}}const sortedOwnDeletions=ownDeletions.sort((a,b)=>{return a.bpPos-b.bpPos});for(let ownD=0;ownD<sortedOwnDeletions.length;ownD++){const bpPosOfDeletion=sortedOwnDeletions[ownD].bpPos;const numberOfDeletions=sortedOwnDeletions[ownD].number;let deletionGaps="";for(let gapD=0;gapD<numberOfDeletions;gapD++){deletionGaps+="-"}eachSeqReadWithGaps.splice(bpPosOfDeletion-1,0,deletionGaps);eachSeqReadWithGaps=eachSeqReadWithGaps.join("").split("")}eachSeqReadWithGaps=eachSeqReadWithGaps.join("").split("");const ownInsertions=[];const ownInsertionsBp=[];for(let componentI=0;componentI<splitSeqReadChunk.length;componentI++){if(splitSeqReadChunk[componentI].slice(-1)==="I"){let bpPosOfInsertion=adjustedSeqReadPos;const numberOfInsertions=Number(splitSeqReadChunk[componentI].slice(0,-1));const nucleotides=[];for(let i=0;i<componentI;i++){const previousComponentNumber=Number(splitSeqReadChunk[i].slice(0,-1));bpPosOfInsertion+=previousComponentNumber}for(let nucI=0;nucI<numberOfInsertions;nucI++){nucleotides.push(eachSeqReadWithGaps[bpPosOfInsertion-1+nucI])}const insertionInfo={bpPos:bpPosOfInsertion,number:numberOfInsertions};const insertionInfoBp={bpPos:bpPosOfInsertion,number:numberOfInsertions,nucleotides};ownInsertions.push(insertionInfo);ownInsertionsBp.push(insertionInfoBp)}}const ownInsertionsCompare=JSON.parse(JSON.stringify(ownInsertions));const sortedOwnInsertions=ownInsertions.sort((a,b)=>{return a.bpPos-b.bpPos});const sortedOwnInsertionsBp=ownInsertionsBp.sort((a,b)=>{return a.bpPos-b.bpPos});for(let ownI=0;ownI<sortedOwnInsertions.length;ownI++){const bpPosOfInsertion=sortedOwnInsertions[ownI].bpPos;const numberOfInsertions=sortedOwnInsertions[ownI].number;for(let numI=0;numI<numberOfInsertions;numI++){eachSeqReadWithGaps.splice(bpPosOfInsertion-1,1)}for(let posI=ownI+1;posI<sortedOwnInsertions.length;posI++){sortedOwnInsertions[posI].bpPos-=numberOfInsertions}}let otherInsertions=allInsertionsInSeqReads.sort((a,b)=>{return a.bpPos-b.bpPos});otherInsertions=otherInsertions.filter((object,index2)=>index2===otherInsertions.findIndex(obj=>JSON.stringify(obj)===JSON.stringify(object)));for(let i=0;i<otherInsertions.length-1;i++){while(otherInsertions[i].bpPos===otherInsertions[i+1].bpPos){if(otherInsertions[i].number>otherInsertions[i+1].number){otherInsertions.splice(i+1,1)}else if(otherInsertions[i].number<otherInsertions[i+1].number){otherInsertions.splice(i,1)}else if(otherInsertions[i].number===otherInsertions[i+1].number){otherInsertions.splice(i,1)}}}for(let otherI=0;otherI<ownInsertionsCompare.length;otherI++){const insertionInfoIndex=otherInsertions.findIndex(e=>e.bpPos===ownInsertionsCompare[otherI].bpPos);if(insertionInfoIndex!==-1){if(otherInsertions[insertionInfoIndex].number>ownInsertionsCompare[otherI].number){otherInsertions[insertionInfoIndex].number=otherInsertions[insertionInfoIndex].number-ownInsertionsCompare[otherI].number}else if(otherInsertions[insertionInfoIndex].number<=ownInsertionsCompare[otherI].number){otherInsertions.splice(insertionInfoIndex,1);otherI--}}}for(let overlapI=0;overlapI<sortedOwnInsertions.length;overlapI++){const insertionInfoIndex=otherInsertions.findIndex(e=>e.bpPos===sortedOwnInsertions[overlapI].bpPos);if(insertionInfoIndex!==-1){if(otherInsertions[insertionInfoIndex].number>sortedOwnInsertions[overlapI].number){otherInsertions[insertionInfoIndex].number=otherInsertions[insertionInfoIndex].number-sortedOwnInsertions[overlapI].number}else if(otherInsertions[insertionInfoIndex].number<=sortedOwnInsertions[overlapI].number){otherInsertions.splice(insertionInfoIndex,1);overlapI--}}}const adjustedOwnInsertionsBp=JSON.parse(JSON.stringify(sortedOwnInsertionsBp));for(let ownI=0;ownI<adjustedOwnInsertionsBp.length;ownI++){let previousInserts=0;for(let i=0;i<ownI;i++){previousInserts+=adjustedOwnInsertionsBp[i].number-1}adjustedOwnInsertionsBp[ownI].bpPos=adjustedOwnInsertionsBp[ownI].bpPos-previousInserts;sortedOwnInsertionsBp[ownI].bpPos=sortedOwnInsertionsBp[ownI].bpPos-previousInserts}for(let otherI=0;otherI<otherInsertions.length;otherI++){for(let ownI=0;ownI<adjustedOwnInsertionsBp.length;ownI++){if(otherInsertions[otherI].bpPos<=sortedOwnInsertionsBp[ownI].bpPos){adjustedOwnInsertionsBp[ownI].bpPos+=1}}}for(let otherI=0;otherI<otherInsertions.length&&otherInsertions[otherI].bpPos<=eachSeqReadWithGaps.length;otherI++){const bpPosOfInsertion=otherInsertions[otherI].bpPos;const numberOfInsertions=otherInsertions[otherI].number;let insertionGaps="";for(let gapI=0;gapI<numberOfInsertions;gapI++){insertionGaps+="-"}eachSeqReadWithGaps.splice(bpPosOfInsertion-1,0,insertionGaps);for(let posI=otherI+1;posI<otherInsertions.length;posI++){otherInsertions[posI].bpPos+=1}}for(let ownI=0;ownI<adjustedOwnInsertionsBp.length;ownI++){const bpPosOfInsertion=adjustedOwnInsertionsBp[ownI].bpPos;const nucleotides=adjustedOwnInsertionsBp[ownI].nucleotides.join("");eachSeqReadWithGaps.splice(bpPosOfInsertion-1,0,nucleotides)}eachSeqReadWithGaps=eachSeqReadWithGaps.join("").split("");if(eachSeqReadWithGaps.length<refSeqWithGaps.length){eachSeqReadWithGaps.push("-".repeat(refSeqWithGaps.length-eachSeqReadWithGaps.length))}seqReadsWithGaps.push({name:seqRead.name,sequence:eachSeqReadWithGaps.join(""),reversed:seqRead.reversed,cigar:seqRead.cigar})});const seqReadLengthsBeforeRefSeqStart=[];seqReads.forEach(seq=>{const splitSeqReadChunk=seq.cigar.match(/([0-9]*[SMDI])/g);let adjustedSeqReadPos=lodashExports.cloneDeep(seq.pos);if(splitSeqReadChunk[0].slice(-1)==="S"){const numOfBeginningSoftClipped=splitSeqReadChunk[0].slice(0,-1);adjustedSeqReadPos=seq.pos-numOfBeginningSoftClipped;if(adjustedSeqReadPos<0){seqReadLengthsBeforeRefSeqStart.push(Math.abs(adjustedSeqReadPos))}}});let longestSeqReadLength=0;for(let i=1;i<seqReadsWithGaps.length;i++){const eachSeqReadWithGaps=seqReadsWithGaps[i].sequence.split("");const splitSeqReadChunk=seqReads[i-1].cigar.match(/([0-9]*[SMDI])/g);let adjustedSeqReadPos=lodashExports.cloneDeep(seqReads[i-1].pos);if(seqReadLengthsBeforeRefSeqStart.length>0){longestSeqReadLength=Math.max(...seqReadLengthsBeforeRefSeqStart)}if(splitSeqReadChunk[0].slice(-1)==="S"){const numOfBeginningSoftClipped=splitSeqReadChunk[0].slice(0,-1);adjustedSeqReadPos=seqReads[i-1].pos-numOfBeginningSoftClipped;if(adjustedSeqReadPos>0){if(longestSeqReadLength>0){eachSeqReadWithGaps.unshift("-".repeat(longestSeqReadLength+1))}seqReadsWithGaps[i].sequence=eachSeqReadWithGaps.join("")}else if(adjustedSeqReadPos<0){if(longestSeqReadLength>0){eachSeqReadWithGaps.unshift("-".repeat(longestSeqReadLength-Math.abs(adjustedSeqReadPos)))}seqReadsWithGaps[i].sequence=eachSeqReadWithGaps.join("")}}else{if(longestSeqReadLength>0){eachSeqReadWithGaps.unshift("-".repeat(longestSeqReadLength+1))}seqReadsWithGaps[i].sequence=eachSeqReadWithGaps.join("")}}if(longestSeqReadLength>0){const splitRefSeqWithGaps=seqReadsWithGaps[0].sequence.split("");splitRefSeqWithGaps.unshift("-".repeat(longestSeqReadLength+1));seqReadsWithGaps[0].sequence=splitRefSeqWithGaps.join("")}const lengthsOfLongerSeqReads=[];for(let i=1;i<seqReadsWithGaps.length;i++){const refSeq2=seqReadsWithGaps[0];if(seqReadsWithGaps[i].sequence.length>refSeq2.sequence.length){lengthsOfLongerSeqReads.push(seqReadsWithGaps[i].sequence.length)}}if(lengthsOfLongerSeqReads.length>0){const longestSeqReadLength2=Math.max(...lengthsOfLongerSeqReads);for(let i=0;i<seqReadsWithGaps.length;i++){if(seqReadsWithGaps[i].sequence.length<longestSeqReadLength2){seqReadsWithGaps[i].sequence+="-".repeat(longestSeqReadLength2-seqReadsWithGaps[i].sequence.length)}}}for(let i=1;i<seqReadsWithGaps.length;i++){const refSeq2=seqReadsWithGaps[0];if(seqReadsWithGaps[i].sequence.length<refSeq2.sequence.length){seqReadsWithGaps[i].sequence+="-".repeat(refSeq2.sequence.length-seqReadsWithGaps[i].sequence.length)}}return seqReadsWithGaps}__name(addGapsToSeqReads,"addGapsToSeqReads");function calculateNebTm(sequence,primerConc,{monovalentCationConc}={}){try{const checkForDegenerateBases=/[^atgc]/i.test(sequence);if(checkForDegenerateBases){throw new Error(`Degenerate bases prohibited in Tm calculation of sequence ${sequence}`)}const seq=sequence.toUpperCase().split("");let h=0;let s=0;let hi=0;let si=0;const r=1.987;const kelvinToCelsius=-273.15;const celsiusToKelvin=273.15;const kilocalToCal=1e3;const sequenceToEnthalpyMap={"AA/TT":-7.9,"AT/TA":-7.2,"TA/AT":-7.2,"CA/GT":-8.5,"GT/CA":-8.4,"CT/GA":-7.8,"GA/CT":-8.2,"CG/GC":-10.6,"GC/CG":-9.8,"GG/CC":-8,"TT/AA":-7.9,"TG/AC":-8.5,"AC/TG":-8.4,"AG/TC":-7.8,"TC/AG":-8.2,"CC/GG":-8,initiationWithTerminalGC:.1,initiationWithTerminalAT:2.3};const sequenceToEntropyMap={"AA/TT":-22.2,"AT/TA":-20.4,"TA/AT":-21.3,"CA/GT":-22.7,"GT/CA":-22.4,"CT/GA":-21,"GA/CT":-22.2,"CG/GC":-27.2,"GC/CG":-24.4,"GG/CC":-19.9,"TT/AA":-22.2,"TG/AC":-22.7,"AC/TG":-22.4,"AG/TC":-21,"TC/AG":-22.2,"CC/GG":-19.9,initiationWithTerminalGC:-2.8,initiationWithTerminalAT:4.1};for(let i=0;i<seq.length;i++){if(i===0||i===seq.length-1){if(seq[i]==="G"||seq[i]==="C"){hi+=sequenceToEnthalpyMap.initiationWithTerminalGC;si+=sequenceToEntropyMap.initiationWithTerminalGC}else if(seq[i]==="A"||seq[i]==="T"){hi+=sequenceToEnthalpyMap.initiationWithTerminalAT;si+=sequenceToEntropyMap.initiationWithTerminalAT}}if(i<seq.length-1){const dimer=seq[i]+seq[i+1];const complement=getComplementSequenceString(dimer).toUpperCase();const dimerDuplex=`${dimer}/${complement}`;if(!sequenceToEnthalpyMap[dimerDuplex]||!sequenceToEntropyMap[dimerDuplex]){throw new Error(`Could not find value for ${dimerDuplex} of sequence ${sequence}`)}h+=sequenceToEnthalpyMap[dimerDuplex];s+=sequenceToEntropyMap[dimerDuplex]}}const deltaH=h+hi;const deltaS=s+si;const numerator=deltaH*kilocalToCal;const denominator=deltaS+r*Math.log(primerConc);const meltingTemp=numerator/denominator+kelvinToCelsius;if(monovalentCationConc){const lnOfMonoConc=Math.log(monovalentCationConc);const gcContent=calculatePercentGC(sequence)/100;const part=4.29*gcContent-3.95;const saltCorrection=part*Math.pow(10,-5)*lnOfMonoConc+Math.pow(9.4,-6)*Math.pow(lnOfMonoConc,2);const adjustedMeltingTemp=1/(1/(meltingTemp+celsiusToKelvin)+saltCorrection)+kelvinToCelsius;return adjustedMeltingTemp}else{return meltingTemp}}catch(err){return`Error calculating Tm for sequence ${sequence}: ${err}`}}__name(calculateNebTm,"calculateNebTm");function calculateNebTa(sequences,primerConc,{monovalentCationConc,polymerase}={}){try{if(sequences.length!==2){throw new Error(`${sequences.length} sequences received when 2 primers were expected`)}const meltingTemperatures=sequences.map(seq=>calculateNebTm(seq,primerConc,{monovalentCationConc}));meltingTemperatures.sort((a,b)=>a-b);const lowerMeltingTemp=meltingTemperatures[0];let annealingTemp;if(polymerase==="Q5"){annealingTemp=lowerMeltingTemp+1;if(annealingTemp>72){annealingTemp=72}}else{annealingTemp=lowerMeltingTemp-3}return annealingTemp}catch(err){return`Error calculating annealing temperature: ${err}`}}__name(calculateNebTa,"calculateNebTa");function getDigestFragmentsForCutsites(sequenceLength,circular,cutsites,opts={}){const fragments=[];const pairs=[];if(!cutsites.length)return[];let sortedCutsites=cutsites.sort((a,b)=>{return a.topSnipPosition-b.topSnipPosition});if(!circular){sortedCutsites=[{topSnipPosition:0,bottomSnipPosition:0,overhangSize:0,type:"START_OR_END_OF_SEQ",name:"START_OF_SEQ"},...sortedCutsites,{topSnipPosition:sequenceLength,bottomSnipPosition:sequenceLength,overhangSize:0,type:"START_OR_END_OF_SEQ",name:"END_OF_SEQ"}]}sortedCutsites.forEach((cutsite1,index2)=>{if(!circular&&!sortedCutsites[index2+1]){return}if(opts.computePartialDigests){sortedCutsites.forEach((cs,index22)=>{if(index22===index2+1||index22===0){return}pairs.push([cutsite1,sortedCutsites[index22]])})}pairs.push([cutsite1,sortedCutsites[index2+1]?sortedCutsites[index2+1]:sortedCutsites[0]])});pairs.forEach(([cut1,cut2])=>{const start=normalizePositionByRangeLength(cut1.topSnipPosition,sequenceLength);const end=normalizePositionByRangeLength(cut2.topSnipPosition-1,sequenceLength);const fragmentRange={start,end};const size=getRangeLength(fragmentRange,sequenceLength);const id=start+"-"+end+"-"+size+"-";fragments.push(__spreadProps(__spreadValues({cut1:__spreadProps(__spreadValues({},cut1),{isOverhangIncludedInFragmentSize:cut1.type!=="START_OR_END_OF_SEQ"&&cut1.overhangSize>0&&cut1.topSnipBeforeBottom}),cut2:__spreadProps(__spreadValues({},cut2),{isOverhangIncludedInFragmentSize:cut2.type!=="START_OR_END_OF_SEQ"&&cut2.overhangSize>0&&!cut2.topSnipBeforeBottom})},fragmentRange),{size,id}))});fragments.filter(fragment=>{if(!fragment.size){return false}return true});return fragments}__name(getDigestFragmentsForCutsites,"getDigestFragmentsForCutsites");function getDigestFragmentsForRestrictionEnzymes(sequence,circular,restrictionEnzymeOrEnzymes,opts){const restrictionEnzymes=Array.isArray(restrictionEnzymeOrEnzymes)?restrictionEnzymeOrEnzymes:[restrictionEnzymeOrEnzymes];const cutsites=lodashExports.flatMap(restrictionEnzymes,restrictionEnzyme=>{return cutSequenceByRestrictionEnzyme(sequence,circular,restrictionEnzyme)});return getDigestFragmentsForCutsites(sequence.length,circular,cutsites,opts)}__name(getDigestFragmentsForRestrictionEnzymes,"getDigestFragmentsForRestrictionEnzymes");function convertAACaretPositionOrRangeToDna(rangeOrCaret){if(typeof rangeOrCaret==="object"&&rangeOrCaret!==null){return convertAARangeToDnaRange(__spreadProps(__spreadValues({},rangeOrCaret),{locations:rangeOrCaret.locations?rangeOrCaret.locations.map(convertAARangeToDnaRange):void 0}))}else{return convertAACaretPositionToDnaCaretPosition(rangeOrCaret)}}__name(convertAACaretPositionOrRangeToDna,"convertAACaretPositionOrRangeToDna");function convertAACaretPositionToDnaCaretPosition(caret){return caret*3}__name(convertAACaretPositionToDnaCaretPosition,"convertAACaretPositionToDnaCaretPosition");function convertAARangeToDnaRange(range){return __spreadProps(__spreadValues({},range),{start:range.start>-1?range.start*3:range.start,end:range.end>-1?range.end*3+2:range.end})}__name(convertAARangeToDnaRange,"convertAARangeToDnaRange");const degenerateRnaToAminoAcidMap=lodashExports.invert(aminoAcidToDegenerateRnaMap);function getMassOfAaString(aaString,numsAfterDecimal=2,divideByThree=false){let sumMass=0;for(let i=0;i<aaString.length;i++){sumMass+=proteinAlphabet[aaString[i]].mass}if(divideByThree){sumMass/=3}return Math.round(sumMass*__pow(10,numsAfterDecimal))/__pow(10,numsAfterDecimal)}__name(getMassOfAaString,"getMassOfAaString");function shiftAnnotationsByLen({seqData,caretPosition,insertLength}){modifiableTypes.forEach(annotationType=>{const existingAnnotations=seqData[annotationType];seqData[annotationType]=adjustAnnotationsToInsert(existingAnnotations,caretPosition,insertLength)})}__name(shiftAnnotationsByLen,"shiftAnnotationsByLen");const FeatureTypes=getFeatureTypes();const featureColors=getFeatureToColorMap();exports.DNAComplementMap=DNAComplementMap;exports.FeatureTypes=FeatureTypes;exports.addGapsToSeqReads=addGapsToSeqReads;exports.adjustAnnotationsToInsert=adjustAnnotationsToInsert;exports.adjustBpsToReplaceOrInsert=adjustBpsToReplaceOrInsert;exports.aliasedEnzymesByName=aliasedEnzymesByName;exports.aminoAcidToDegenerateDnaMap=aminoAcidToDegenerateDnaMap;exports.aminoAcidToDegenerateRnaMap=aminoAcidToDegenerateRnaMap;exports.annotateSingleSeq=annotateSingleSeq;exports.annotationTypes=annotationTypes;exports.autoAnnotate=autoAnnotate;exports.bioData=bioData;exports.calculateNebTa=calculateNebTa;exports.calculateNebTm=calculateNebTm;exports.calculatePercentGC=calculatePercentGC;exports.calculateTm=calculateTm;exports.computeDigestFragments=computeDigestFragments;exports.condensePairwiseAlignmentDifferences=condensePairwiseAlignmentDifferences;exports.convertAACaretPositionOrRangeToDna=convertAACaretPositionOrRangeToDna;exports.convertApELikeRegexToRegex=convertApELikeRegexToRegex;exports.convertDnaCaretPositionOrRangeToAA=convertDnaCaretPositionOrRangeToAA;exports.convertProteinSeqToDNAIupac=convertProteinSeqToDNAIupac;exports.cutSequenceByRestrictionEnzyme=cutSequenceByRestrictionEnzyme;exports.defaultEnzymesByName=defaultEnzymesByName;exports.degenerateDnaToAminoAcidMap=degenerateDnaToAminoAcidMap;exports.degenerateRnaToAminoAcidMap=degenerateRnaToAminoAcidMap;exports.deleteSequenceDataAtRange=deleteSequenceDataAtRange;exports.doesEnzymeChopOutsideOfRecognitionSite=doesEnzymeChopOutsideOfRecognitionSite;exports.featureColors=featureColors;exports.filterAminoAcidSequenceString=filterAminoAcidSequenceString;exports.filterSequenceString=filterSequenceString;exports.findNearestRangeOfSequenceOverlapToPosition=findNearestRangeOfSequenceOverlapToPosition;exports.findOrfsInPlasmid=findOrfsInPlasmid;exports.findSequenceMatches=findSequenceMatches;exports.genbankFeatureTypes=genbankFeatureTypes;exports.generateAnnotations=generateAnnotations;exports.generateSequenceData=generateSequenceData;exports.getAllInsertionsInSeqReads=getAllInsertionsInSeqReads;exports.getAminoAcidDataForEachBaseOfDna=getAminoAcidDataForEachBaseOfDna;exports.getAminoAcidFromSequenceTriplet=getAminoAcidFromSequenceTriplet;exports.getAminoAcidStringFromSequenceString=getAminoAcidStringFromSequenceString;exports.getCodonRangeForAASliver=getCodonRangeForAASliver;exports.getComplementAminoAcidStringFromSequenceString=getComplementAminoAcidStringFromSequenceString;exports.getComplementSequenceAndAnnotations=getComplementSequenceAndAnnotations;exports.getComplementSequenceString=getComplementSequenceString;exports.getCutsiteType=getCutsiteType;exports.getCutsitesFromSequence=getCutsitesFromSequence;exports.getDegenerateDnaStringFromAAString=getDegenerateDnaStringFromAAString;exports.getDegenerateRnaStringFromAAString=getDegenerateRnaStringFromAAString;exports.getDiffFromSeqs=getDiffFromSeqs;exports.getDigestFragmentsForCutsites=getDigestFragmentsForCutsites;exports.getDigestFragmentsForRestrictionEnzymes=getDigestFragmentsForRestrictionEnzymes;exports.getDigestFragsForSeqAndEnzymes=getDigestFragsForSeqAndEnzymes;exports.getFeatureToColorMap=getFeatureToColorMap;exports.getFeatureTypes=getFeatureTypes;exports.getInsertBetweenVals=getInsertBetweenVals;exports.getLeftAndRightOfSequenceInRangeGivenPosition=getLeftAndRightOfSequenceInRangeGivenPosition;exports.getMassOfAaString=getMassOfAaString;exports.getMergedFeatureMap=getMergedFeatureMap;exports.getOrfsFromSequence=getOrfsFromSequence;exports.getOverlapBetweenTwoSequences=getOverlapBetweenTwoSequences;exports.getPossiblePartsFromSequenceAndEnzymes=getPossiblePartsFromSequenceAndEnzyme;exports.getReverseAminoAcidStringFromSequenceString=getReverseAminoAcidStringFromSequenceString;exports.getReverseComplementAminoAcidStringFromSequenceString=getReverseComplementAminoAcidStringFromSequenceString;exports.getReverseComplementAnnotation=getReverseComplementAnnotation;exports.getReverseComplementSequenceAndAnnotations=getReverseComplementSequenceAndAnnoations;exports.getReverseComplementSequenceString=getReverseComplementSequenceString;exports.getReverseSequenceString=getReverseSequenceString;exports.getSequenceDataBetweenRange=getSequenceDataBetweenRange;exports.getVirtualDigest=getVirtualDigest;exports.guessIfSequenceIsDnaAndNotProtein=guessIfSequenceIsDnaAndNotProtein;exports.insertGapsIntoRefSeq=insertGapsIntoRefSeq;exports.insertSequenceDataAtPosition=insertSequenceDataAtPositionOrRange;exports.insertSequenceDataAtPositionOrRange=insertSequenceDataAtPositionOrRange;exports.isEnzymeType2S=isEnzymeType2S;exports.mapAnnotationsToRows=mapAnnotationsToRows;exports.modifiableTypes=modifiableTypes;exports.patchSeqWithDiff=patchSeqWithDiff;exports.prepareCircularViewData=prepareCircularViewData;exports.prepareRowData=prepareRowData;exports.proteinAlphabet=proteinAlphabet;exports.reverseSeqDiff=reverseSeqDiff;exports.rotateBpsToPosition=rotateBpsToPosition;exports.rotateSequenceDataToPosition=rotateSequenceDataToPosition;exports.shiftAnnotationsByLen=shiftAnnotationsByLen;exports.threeLetterSequenceStringToAminoAcidMap=threeLetterSequenceStringToAminoAcidMap;exports.tidyUpAnnotation=tidyUpAnnotation;exports.tidyUpSequenceData=tidyUpSequenceData;