@synsci/cli-darwin-x64 1.1.71 → 1.1.72

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (339) hide show
  1. package/bin/skills/citation-management/SKILL.md +1109 -0
  2. package/bin/skills/citation-management/assets/bibtex_template.bib +264 -0
  3. package/bin/skills/citation-management/assets/citation_checklist.md +386 -0
  4. package/bin/skills/citation-management/references/bibtex_formatting.md +908 -0
  5. package/bin/skills/citation-management/references/citation_validation.md +794 -0
  6. package/bin/skills/citation-management/references/google_scholar_search.md +725 -0
  7. package/bin/skills/citation-management/references/metadata_extraction.md +870 -0
  8. package/bin/skills/citation-management/references/pubmed_search.md +839 -0
  9. package/bin/skills/citation-management/scripts/doi_to_bibtex.py +182 -0
  10. package/bin/skills/citation-management/scripts/extract_metadata.py +570 -0
  11. package/bin/skills/citation-management/scripts/format_bibtex.py +349 -0
  12. package/bin/skills/citation-management/scripts/search_google_scholar.py +251 -0
  13. package/bin/skills/citation-management/scripts/search_pubmed.py +348 -0
  14. package/bin/skills/citation-management/scripts/validate_citations.py +494 -0
  15. package/bin/skills/clinical-decision-support/README.md +129 -0
  16. package/bin/skills/clinical-decision-support/SKILL.md +506 -0
  17. package/bin/skills/clinical-decision-support/assets/biomarker_report_template.tex +380 -0
  18. package/bin/skills/clinical-decision-support/assets/clinical_pathway_template.tex +222 -0
  19. package/bin/skills/clinical-decision-support/assets/cohort_analysis_template.tex +359 -0
  20. package/bin/skills/clinical-decision-support/assets/color_schemes.tex +149 -0
  21. package/bin/skills/clinical-decision-support/assets/example_gbm_cohort.md +208 -0
  22. package/bin/skills/clinical-decision-support/assets/recommendation_strength_guide.md +328 -0
  23. package/bin/skills/clinical-decision-support/assets/treatment_recommendation_template.tex +529 -0
  24. package/bin/skills/clinical-decision-support/references/biomarker_classification.md +719 -0
  25. package/bin/skills/clinical-decision-support/references/clinical_decision_algorithms.md +604 -0
  26. package/bin/skills/clinical-decision-support/references/evidence_synthesis.md +840 -0
  27. package/bin/skills/clinical-decision-support/references/outcome_analysis.md +640 -0
  28. package/bin/skills/clinical-decision-support/references/patient_cohort_analysis.md +427 -0
  29. package/bin/skills/clinical-decision-support/references/treatment_recommendations.md +521 -0
  30. package/bin/skills/clinical-decision-support/scripts/biomarker_classifier.py +383 -0
  31. package/bin/skills/clinical-decision-support/scripts/build_decision_tree.py +417 -0
  32. package/bin/skills/clinical-decision-support/scripts/create_cohort_tables.py +509 -0
  33. package/bin/skills/clinical-decision-support/scripts/generate_survival_analysis.py +441 -0
  34. package/bin/skills/clinical-decision-support/scripts/validate_cds_document.py +326 -0
  35. package/bin/skills/clinical-reports/IMPLEMENTATION_SUMMARY.md +641 -0
  36. package/bin/skills/clinical-reports/README.md +236 -0
  37. package/bin/skills/clinical-reports/SKILL.md +1127 -0
  38. package/bin/skills/clinical-reports/assets/case_report_template.md +352 -0
  39. package/bin/skills/clinical-reports/assets/clinical_trial_csr_template.md +353 -0
  40. package/bin/skills/clinical-reports/assets/clinical_trial_sae_template.md +359 -0
  41. package/bin/skills/clinical-reports/assets/consult_note_template.md +305 -0
  42. package/bin/skills/clinical-reports/assets/discharge_summary_template.md +453 -0
  43. package/bin/skills/clinical-reports/assets/hipaa_compliance_checklist.md +395 -0
  44. package/bin/skills/clinical-reports/assets/history_physical_template.md +305 -0
  45. package/bin/skills/clinical-reports/assets/lab_report_template.md +309 -0
  46. package/bin/skills/clinical-reports/assets/pathology_report_template.md +249 -0
  47. package/bin/skills/clinical-reports/assets/quality_checklist.md +338 -0
  48. package/bin/skills/clinical-reports/assets/radiology_report_template.md +318 -0
  49. package/bin/skills/clinical-reports/assets/soap_note_template.md +253 -0
  50. package/bin/skills/clinical-reports/references/case_report_guidelines.md +570 -0
  51. package/bin/skills/clinical-reports/references/clinical_trial_reporting.md +693 -0
  52. package/bin/skills/clinical-reports/references/data_presentation.md +530 -0
  53. package/bin/skills/clinical-reports/references/diagnostic_reports_standards.md +629 -0
  54. package/bin/skills/clinical-reports/references/medical_terminology.md +588 -0
  55. package/bin/skills/clinical-reports/references/patient_documentation.md +744 -0
  56. package/bin/skills/clinical-reports/references/peer_review_standards.md +585 -0
  57. package/bin/skills/clinical-reports/references/regulatory_compliance.md +577 -0
  58. package/bin/skills/clinical-reports/scripts/check_deidentification.py +332 -0
  59. package/bin/skills/clinical-reports/scripts/compliance_checker.py +78 -0
  60. package/bin/skills/clinical-reports/scripts/extract_clinical_data.py +97 -0
  61. package/bin/skills/clinical-reports/scripts/format_adverse_events.py +97 -0
  62. package/bin/skills/clinical-reports/scripts/generate_report_template.py +149 -0
  63. package/bin/skills/clinical-reports/scripts/terminology_validator.py +126 -0
  64. package/bin/skills/clinical-reports/scripts/validate_case_report.py +323 -0
  65. package/bin/skills/clinical-reports/scripts/validate_trial_report.py +88 -0
  66. package/bin/skills/fireworks-ai/SKILL.md +665 -0
  67. package/bin/skills/generate-image/SKILL.md +178 -0
  68. package/bin/skills/generate-image/scripts/generate_image.py +254 -0
  69. package/bin/skills/groq/SKILL.md +347 -0
  70. package/bin/skills/hypothesis-generation/SKILL.md +293 -0
  71. package/bin/skills/hypothesis-generation/assets/FORMATTING_GUIDE.md +672 -0
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  73. package/bin/skills/hypothesis-generation/assets/hypothesis_report_template.tex +572 -0
  74. package/bin/skills/hypothesis-generation/references/experimental_design_patterns.md +329 -0
  75. package/bin/skills/hypothesis-generation/references/hypothesis_quality_criteria.md +198 -0
  76. package/bin/skills/hypothesis-generation/references/literature_search_strategies.md +622 -0
  77. package/bin/skills/latex-posters/README.md +417 -0
  78. package/bin/skills/latex-posters/SKILL.md +1602 -0
  79. package/bin/skills/latex-posters/assets/baposter_template.tex +257 -0
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  81. package/bin/skills/latex-posters/assets/poster_quality_checklist.md +358 -0
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  83. package/bin/skills/latex-posters/references/latex_poster_packages.md +745 -0
  84. package/bin/skills/latex-posters/references/poster_content_guide.md +748 -0
  85. package/bin/skills/latex-posters/references/poster_design_principles.md +806 -0
  86. package/bin/skills/latex-posters/references/poster_layout_design.md +900 -0
  87. package/bin/skills/latex-posters/scripts/review_poster.sh +214 -0
  88. package/bin/skills/literature-review/SKILL.md +641 -0
  89. package/bin/skills/literature-review/assets/review_template.md +412 -0
  90. package/bin/skills/literature-review/references/citation_styles.md +166 -0
  91. package/bin/skills/literature-review/references/database_strategies.md +455 -0
  92. package/bin/skills/literature-review/scripts/generate_pdf.py +184 -0
  93. package/bin/skills/literature-review/scripts/search_databases.py +310 -0
  94. package/bin/skills/literature-review/scripts/verify_citations.py +218 -0
  95. package/bin/skills/market-research-reports/SKILL.md +904 -0
  96. package/bin/skills/market-research-reports/assets/FORMATTING_GUIDE.md +428 -0
  97. package/bin/skills/market-research-reports/assets/market_report_template.tex +1380 -0
  98. package/bin/skills/market-research-reports/assets/market_research.sty +564 -0
  99. package/bin/skills/market-research-reports/references/data_analysis_patterns.md +548 -0
  100. package/bin/skills/market-research-reports/references/report_structure_guide.md +999 -0
  101. package/bin/skills/market-research-reports/references/visual_generation_guide.md +1077 -0
  102. package/bin/skills/market-research-reports/scripts/generate_market_visuals.py +472 -0
  103. package/bin/skills/markitdown/INSTALLATION_GUIDE.md +318 -0
  104. package/bin/skills/markitdown/LICENSE.txt +22 -0
  105. package/bin/skills/markitdown/OPENROUTER_INTEGRATION.md +359 -0
  106. package/bin/skills/markitdown/QUICK_REFERENCE.md +309 -0
  107. package/bin/skills/markitdown/README.md +184 -0
  108. package/bin/skills/markitdown/SKILL.md +486 -0
  109. package/bin/skills/markitdown/SKILL_SUMMARY.md +307 -0
  110. package/bin/skills/markitdown/assets/example_usage.md +463 -0
  111. package/bin/skills/markitdown/references/api_reference.md +399 -0
  112. package/bin/skills/markitdown/references/file_formats.md +542 -0
  113. package/bin/skills/markitdown/scripts/batch_convert.py +195 -0
  114. package/bin/skills/markitdown/scripts/convert_literature.py +262 -0
  115. package/bin/skills/markitdown/scripts/convert_with_ai.py +224 -0
  116. package/bin/skills/ml-paper-writing/SKILL.md +937 -0
  117. package/bin/skills/ml-paper-writing/references/checklists.md +361 -0
  118. package/bin/skills/ml-paper-writing/references/citation-workflow.md +562 -0
  119. package/bin/skills/ml-paper-writing/references/reviewer-guidelines.md +367 -0
  120. package/bin/skills/ml-paper-writing/references/sources.md +159 -0
  121. package/bin/skills/ml-paper-writing/references/writing-guide.md +476 -0
  122. package/bin/skills/ml-paper-writing/templates/README.md +251 -0
  123. package/bin/skills/ml-paper-writing/templates/aaai2026/README.md +534 -0
  124. package/bin/skills/ml-paper-writing/templates/aaai2026/aaai2026-unified-supp.tex +144 -0
  125. package/bin/skills/ml-paper-writing/templates/aaai2026/aaai2026-unified-template.tex +952 -0
  126. package/bin/skills/ml-paper-writing/templates/aaai2026/aaai2026.bib +111 -0
  127. package/bin/skills/ml-paper-writing/templates/aaai2026/aaai2026.bst +1493 -0
  128. package/bin/skills/ml-paper-writing/templates/aaai2026/aaai2026.sty +315 -0
  129. package/bin/skills/ml-paper-writing/templates/acl/README.md +50 -0
  130. package/bin/skills/ml-paper-writing/templates/acl/acl.sty +312 -0
  131. package/bin/skills/ml-paper-writing/templates/acl/acl_latex.tex +377 -0
  132. package/bin/skills/ml-paper-writing/templates/acl/acl_lualatex.tex +101 -0
  133. package/bin/skills/ml-paper-writing/templates/acl/acl_natbib.bst +1940 -0
  134. package/bin/skills/ml-paper-writing/templates/acl/anthology.bib.txt +26 -0
  135. package/bin/skills/ml-paper-writing/templates/acl/custom.bib +70 -0
  136. package/bin/skills/ml-paper-writing/templates/acl/formatting.md +326 -0
  137. package/bin/skills/ml-paper-writing/templates/colm2025/README.md +3 -0
  138. package/bin/skills/ml-paper-writing/templates/colm2025/colm2025_conference.bib +11 -0
  139. package/bin/skills/ml-paper-writing/templates/colm2025/colm2025_conference.bst +1440 -0
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  142. package/bin/skills/ml-paper-writing/templates/colm2025/colm2025_conference.tex +305 -0
  143. package/bin/skills/ml-paper-writing/templates/colm2025/fancyhdr.sty +485 -0
  144. package/bin/skills/ml-paper-writing/templates/colm2025/math_commands.tex +508 -0
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  146. package/bin/skills/ml-paper-writing/templates/iclr2026/fancyhdr.sty +485 -0
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  167. package/bin/skills/paper-2-web/SKILL.md +491 -0
  168. package/bin/skills/paper-2-web/references/installation.md +141 -0
  169. package/bin/skills/paper-2-web/references/paper2poster.md +346 -0
  170. package/bin/skills/paper-2-web/references/paper2video.md +305 -0
  171. package/bin/skills/paper-2-web/references/paper2web.md +187 -0
  172. package/bin/skills/paper-2-web/references/usage_examples.md +436 -0
  173. package/bin/skills/peer-review/SKILL.md +702 -0
  174. package/bin/skills/peer-review/references/calibration_guidelines.md +196 -0
  175. package/bin/skills/peer-review/references/common_issues.md +552 -0
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  177. package/bin/skills/peer-review/references/reporting_standards.md +290 -0
  178. package/bin/skills/peer-review/references/scoring_rubric.md +239 -0
  179. package/bin/skills/pptx-posters/SKILL.md +410 -0
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  185. package/bin/skills/research-grants/README.md +285 -0
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  191. package/bin/skills/research-grants/references/darpa_guidelines.md +636 -0
  192. package/bin/skills/research-grants/references/doe_guidelines.md +586 -0
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@@ -0,0 +1,486 @@
1
+ ---
2
+ name: markitdown
3
+ description: "Convert files and office documents to Markdown. Supports PDF, DOCX, PPTX, XLSX, images (with OCR), audio (with transcription), HTML, CSV, JSON, XML, ZIP, YouTube URLs, EPubs and more."
4
+ allowed-tools: [Read, Write, Edit, Bash]
5
+ license: MIT
6
+ source: https://github.com/microsoft/markitdown
7
+ ---
8
+
9
+ # MarkItDown - File to Markdown Conversion
10
+
11
+ ## Overview
12
+
13
+ MarkItDown is a Python tool developed by Microsoft for converting various file formats to Markdown. It's particularly useful for converting documents into LLM-friendly text format, as Markdown is token-efficient and well-understood by modern language models.
14
+
15
+ **Key Benefits**:
16
+ - Convert documents to clean, structured Markdown
17
+ - Token-efficient format for LLM processing
18
+ - Supports 15+ file formats
19
+ - Optional AI-enhanced image descriptions
20
+ - OCR for images and scanned documents
21
+ - Speech transcription for audio files
22
+
23
+ ## Visual Enhancement with Scientific Schematics
24
+
25
+ **When creating documents with this skill, always consider adding scientific diagrams and schematics to enhance visual communication.**
26
+
27
+ If your document does not already contain schematics or diagrams:
28
+ - Use the **scientific-schematics** skill to generate AI-powered publication-quality diagrams
29
+ - Simply describe your desired diagram in natural language
30
+ - Nano Banana Pro will automatically generate, review, and refine the schematic
31
+
32
+ **For new documents:** Scientific schematics should be generated by default to visually represent key concepts, workflows, architectures, or relationships described in the text.
33
+
34
+ **How to generate schematics:**
35
+ ```bash
36
+ python scripts/generate_schematic.py "your diagram description" -o figures/output.png
37
+ ```
38
+
39
+ The AI will automatically:
40
+ - Create publication-quality images with proper formatting
41
+ - Review and refine through multiple iterations
42
+ - Ensure accessibility (colorblind-friendly, high contrast)
43
+ - Save outputs in the figures/ directory
44
+
45
+ **When to add schematics:**
46
+ - Document conversion workflow diagrams
47
+ - File format architecture illustrations
48
+ - OCR processing pipeline diagrams
49
+ - Integration workflow visualizations
50
+ - System architecture diagrams
51
+ - Data flow diagrams
52
+ - Any complex concept that benefits from visualization
53
+
54
+ For detailed guidance on creating schematics, refer to the scientific-schematics skill documentation.
55
+
56
+ ---
57
+
58
+ ## Supported Formats
59
+
60
+ | Format | Description | Notes |
61
+ |--------|-------------|-------|
62
+ | **PDF** | Portable Document Format | Full text extraction |
63
+ | **DOCX** | Microsoft Word | Tables, formatting preserved |
64
+ | **PPTX** | PowerPoint | Slides with notes |
65
+ | **XLSX** | Excel spreadsheets | Tables and data |
66
+ | **Images** | JPEG, PNG, GIF, WebP | EXIF metadata + OCR |
67
+ | **Audio** | WAV, MP3 | Metadata + transcription |
68
+ | **HTML** | Web pages | Clean conversion |
69
+ | **CSV** | Comma-separated values | Table format |
70
+ | **JSON** | JSON data | Structured representation |
71
+ | **XML** | XML documents | Structured format |
72
+ | **ZIP** | Archive files | Iterates contents |
73
+ | **EPUB** | E-books | Full text extraction |
74
+ | **YouTube** | Video URLs | Fetch transcriptions |
75
+
76
+ ## Quick Start
77
+
78
+ ### Installation
79
+
80
+ ```bash
81
+ # Install with all features
82
+ pip install 'markitdown[all]'
83
+
84
+ # Or from source
85
+ git clone https://github.com/microsoft/markitdown.git
86
+ cd markitdown
87
+ pip install -e 'packages/markitdown[all]'
88
+ ```
89
+
90
+ ### Command-Line Usage
91
+
92
+ ```bash
93
+ # Basic conversion
94
+ markitdown document.pdf > output.md
95
+
96
+ # Specify output file
97
+ markitdown document.pdf -o output.md
98
+
99
+ # Pipe content
100
+ cat document.pdf | markitdown > output.md
101
+
102
+ # Enable plugins
103
+ markitdown --list-plugins # List available plugins
104
+ markitdown --use-plugins document.pdf -o output.md
105
+ ```
106
+
107
+ ### Python API
108
+
109
+ ```python
110
+ from markitdown import MarkItDown
111
+
112
+ # Basic usage
113
+ md = MarkItDown()
114
+ result = md.convert("document.pdf")
115
+ print(result.text_content)
116
+
117
+ # Convert from stream
118
+ with open("document.pdf", "rb") as f:
119
+ result = md.convert_stream(f, file_extension=".pdf")
120
+ print(result.text_content)
121
+ ```
122
+
123
+ ## Advanced Features
124
+
125
+ ### 1. AI-Enhanced Image Descriptions
126
+
127
+ Use LLMs via OpenRouter to generate detailed image descriptions (for PPTX and image files):
128
+
129
+ ```python
130
+ from markitdown import MarkItDown
131
+ from openai import OpenAI
132
+
133
+ # Initialize OpenRouter client (OpenAI-compatible API)
134
+ client = OpenAI(
135
+ api_key="your-openrouter-api-key",
136
+ base_url="https://openrouter.ai/api/v1"
137
+ )
138
+
139
+ md = MarkItDown(
140
+ llm_client=client,
141
+ llm_model="anthropic/claude-sonnet-4.5", # recommended for scientific vision
142
+ llm_prompt="Describe this image in detail for scientific documentation"
143
+ )
144
+
145
+ result = md.convert("presentation.pptx")
146
+ print(result.text_content)
147
+ ```
148
+
149
+ ### 2. Azure Document Intelligence
150
+
151
+ For enhanced PDF conversion with Microsoft Document Intelligence:
152
+
153
+ ```bash
154
+ # Command line
155
+ markitdown document.pdf -o output.md -d -e "<document_intelligence_endpoint>"
156
+ ```
157
+
158
+ ```python
159
+ # Python API
160
+ from markitdown import MarkItDown
161
+
162
+ md = MarkItDown(docintel_endpoint="<document_intelligence_endpoint>")
163
+ result = md.convert("complex_document.pdf")
164
+ print(result.text_content)
165
+ ```
166
+
167
+ ### 3. Plugin System
168
+
169
+ MarkItDown supports 3rd-party plugins for extending functionality:
170
+
171
+ ```bash
172
+ # List installed plugins
173
+ markitdown --list-plugins
174
+
175
+ # Enable plugins
176
+ markitdown --use-plugins file.pdf -o output.md
177
+ ```
178
+
179
+ Find plugins on GitHub with hashtag: `#markitdown-plugin`
180
+
181
+ ## Optional Dependencies
182
+
183
+ Control which file formats you support:
184
+
185
+ ```bash
186
+ # Install specific formats
187
+ pip install 'markitdown[pdf, docx, pptx]'
188
+
189
+ # All available options:
190
+ # [all] - All optional dependencies
191
+ # [pptx] - PowerPoint files
192
+ # [docx] - Word documents
193
+ # [xlsx] - Excel spreadsheets
194
+ # [xls] - Older Excel files
195
+ # [pdf] - PDF documents
196
+ # [outlook] - Outlook messages
197
+ # [az-doc-intel] - Azure Document Intelligence
198
+ # [audio-transcription] - WAV and MP3 transcription
199
+ # [youtube-transcription] - YouTube video transcription
200
+ ```
201
+
202
+ ## Common Use Cases
203
+
204
+ ### 1. Convert Scientific Papers to Markdown
205
+
206
+ ```python
207
+ from markitdown import MarkItDown
208
+
209
+ md = MarkItDown()
210
+
211
+ # Convert PDF paper
212
+ result = md.convert("research_paper.pdf")
213
+ with open("paper.md", "w") as f:
214
+ f.write(result.text_content)
215
+ ```
216
+
217
+ ### 2. Extract Data from Excel for Analysis
218
+
219
+ ```python
220
+ from markitdown import MarkItDown
221
+
222
+ md = MarkItDown()
223
+ result = md.convert("data.xlsx")
224
+
225
+ # Result will be in Markdown table format
226
+ print(result.text_content)
227
+ ```
228
+
229
+ ### 3. Process Multiple Documents
230
+
231
+ ```python
232
+ from markitdown import MarkItDown
233
+ import os
234
+ from pathlib import Path
235
+
236
+ md = MarkItDown()
237
+
238
+ # Process all PDFs in a directory
239
+ pdf_dir = Path("papers/")
240
+ output_dir = Path("markdown_output/")
241
+ output_dir.mkdir(exist_ok=True)
242
+
243
+ for pdf_file in pdf_dir.glob("*.pdf"):
244
+ result = md.convert(str(pdf_file))
245
+ output_file = output_dir / f"{pdf_file.stem}.md"
246
+ output_file.write_text(result.text_content)
247
+ print(f"Converted: {pdf_file.name}")
248
+ ```
249
+
250
+ ### 4. Convert PowerPoint with AI Descriptions
251
+
252
+ ```python
253
+ from markitdown import MarkItDown
254
+ from openai import OpenAI
255
+
256
+ # Use OpenRouter for access to multiple AI models
257
+ client = OpenAI(
258
+ api_key="your-openrouter-api-key",
259
+ base_url="https://openrouter.ai/api/v1"
260
+ )
261
+
262
+ md = MarkItDown(
263
+ llm_client=client,
264
+ llm_model="anthropic/claude-sonnet-4.5", # recommended for presentations
265
+ llm_prompt="Describe this slide image in detail, focusing on key visual elements and data"
266
+ )
267
+
268
+ result = md.convert("presentation.pptx")
269
+ with open("presentation.md", "w") as f:
270
+ f.write(result.text_content)
271
+ ```
272
+
273
+ ### 5. Batch Convert with Different Formats
274
+
275
+ ```python
276
+ from markitdown import MarkItDown
277
+ from pathlib import Path
278
+
279
+ md = MarkItDown()
280
+
281
+ # Files to convert
282
+ files = [
283
+ "document.pdf",
284
+ "spreadsheet.xlsx",
285
+ "presentation.pptx",
286
+ "notes.docx"
287
+ ]
288
+
289
+ for file in files:
290
+ try:
291
+ result = md.convert(file)
292
+ output = Path(file).stem + ".md"
293
+ with open(output, "w") as f:
294
+ f.write(result.text_content)
295
+ print(f"✓ Converted {file}")
296
+ except Exception as e:
297
+ print(f"✗ Error converting {file}: {e}")
298
+ ```
299
+
300
+ ### 6. Extract YouTube Video Transcription
301
+
302
+ ```python
303
+ from markitdown import MarkItDown
304
+
305
+ md = MarkItDown()
306
+
307
+ # Convert YouTube video to transcript
308
+ result = md.convert("https://www.youtube.com/watch?v=VIDEO_ID")
309
+ print(result.text_content)
310
+ ```
311
+
312
+ ## Docker Usage
313
+
314
+ ```bash
315
+ # Build image
316
+ docker build -t markitdown:latest .
317
+
318
+ # Run conversion
319
+ docker run --rm -i markitdown:latest < ~/document.pdf > output.md
320
+ ```
321
+
322
+ ## Best Practices
323
+
324
+ ### 1. Choose the Right Conversion Method
325
+
326
+ - **Simple documents**: Use basic `MarkItDown()`
327
+ - **Complex PDFs**: Use Azure Document Intelligence
328
+ - **Visual content**: Enable AI image descriptions
329
+ - **Scanned documents**: Ensure OCR dependencies are installed
330
+
331
+ ### 2. Handle Errors Gracefully
332
+
333
+ ```python
334
+ from markitdown import MarkItDown
335
+
336
+ md = MarkItDown()
337
+
338
+ try:
339
+ result = md.convert("document.pdf")
340
+ print(result.text_content)
341
+ except FileNotFoundError:
342
+ print("File not found")
343
+ except Exception as e:
344
+ print(f"Conversion error: {e}")
345
+ ```
346
+
347
+ ### 3. Process Large Files Efficiently
348
+
349
+ ```python
350
+ from markitdown import MarkItDown
351
+
352
+ md = MarkItDown()
353
+
354
+ # For large files, use streaming
355
+ with open("large_file.pdf", "rb") as f:
356
+ result = md.convert_stream(f, file_extension=".pdf")
357
+
358
+ # Process in chunks or save directly
359
+ with open("output.md", "w") as out:
360
+ out.write(result.text_content)
361
+ ```
362
+
363
+ ### 4. Optimize for Token Efficiency
364
+
365
+ Markdown output is already token-efficient, but you can:
366
+ - Remove excessive whitespace
367
+ - Consolidate similar sections
368
+ - Strip metadata if not needed
369
+
370
+ ```python
371
+ from markitdown import MarkItDown
372
+ import re
373
+
374
+ md = MarkItDown()
375
+ result = md.convert("document.pdf")
376
+
377
+ # Clean up extra whitespace
378
+ clean_text = re.sub(r'\n{3,}', '\n\n', result.text_content)
379
+ clean_text = clean_text.strip()
380
+
381
+ print(clean_text)
382
+ ```
383
+
384
+ ## Integration with Scientific Workflows
385
+
386
+ ### Convert Literature for Review
387
+
388
+ ```python
389
+ from markitdown import MarkItDown
390
+ from pathlib import Path
391
+
392
+ md = MarkItDown()
393
+
394
+ # Convert all papers in literature folder
395
+ papers_dir = Path("literature/pdfs")
396
+ output_dir = Path("literature/markdown")
397
+ output_dir.mkdir(exist_ok=True)
398
+
399
+ for paper in papers_dir.glob("*.pdf"):
400
+ result = md.convert(str(paper))
401
+
402
+ # Save with metadata
403
+ output_file = output_dir / f"{paper.stem}.md"
404
+ content = f"# {paper.stem}\n\n"
405
+ content += f"**Source**: {paper.name}\n\n"
406
+ content += "---\n\n"
407
+ content += result.text_content
408
+
409
+ output_file.write_text(content)
410
+
411
+ # For AI-enhanced conversion with figures
412
+ from openai import OpenAI
413
+
414
+ client = OpenAI(
415
+ api_key="your-openrouter-api-key",
416
+ base_url="https://openrouter.ai/api/v1"
417
+ )
418
+
419
+ md_ai = MarkItDown(
420
+ llm_client=client,
421
+ llm_model="anthropic/claude-sonnet-4.5",
422
+ llm_prompt="Describe scientific figures with technical precision"
423
+ )
424
+ ```
425
+
426
+ ### Extract Tables for Analysis
427
+
428
+ ```python
429
+ from markitdown import MarkItDown
430
+ import re
431
+
432
+ md = MarkItDown()
433
+ result = md.convert("data_tables.xlsx")
434
+
435
+ # Markdown tables can be parsed or used directly
436
+ print(result.text_content)
437
+ ```
438
+
439
+ ## Troubleshooting
440
+
441
+ ### Common Issues
442
+
443
+ 1. **Missing dependencies**: Install feature-specific packages
444
+ ```bash
445
+ pip install 'markitdown[pdf]' # For PDF support
446
+ ```
447
+
448
+ 2. **Binary file errors**: Ensure files are opened in binary mode
449
+ ```python
450
+ with open("file.pdf", "rb") as f: # Note the "rb"
451
+ result = md.convert_stream(f, file_extension=".pdf")
452
+ ```
453
+
454
+ 3. **OCR not working**: Install tesseract
455
+ ```bash
456
+ # macOS
457
+ brew install tesseract
458
+
459
+ # Ubuntu
460
+ sudo apt-get install tesseract-ocr
461
+ ```
462
+
463
+ ## Performance Considerations
464
+
465
+ - **PDF files**: Large PDFs may take time; consider page ranges if supported
466
+ - **Image OCR**: OCR processing is CPU-intensive
467
+ - **Audio transcription**: Requires additional compute resources
468
+ - **AI image descriptions**: Requires API calls (costs may apply)
469
+
470
+ ## Next Steps
471
+
472
+ - See `references/api_reference.md` for complete API documentation
473
+ - Check `references/file_formats.md` for format-specific details
474
+ - Review `scripts/batch_convert.py` for automation examples
475
+ - Explore `scripts/convert_with_ai.py` for AI-enhanced conversions
476
+
477
+ ## Resources
478
+
479
+ - **MarkItDown GitHub**: https://github.com/microsoft/markitdown
480
+ - **PyPI**: https://pypi.org/project/markitdown/
481
+ - **OpenRouter**: https://openrouter.ai (for AI-enhanced conversions)
482
+ - **OpenRouter API Keys**: https://openrouter.ai/keys
483
+ - **OpenRouter Models**: https://openrouter.ai/models
484
+ - **MCP Server**: markitdown-mcp (for Claude Desktop integration)
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+ - **Plugin Development**: See `packages/markitdown-sample-plugin`
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+