@skaterqiang/protege-js 0.1.0

package/sample/ontologies/ogms.owl

@@ -0,0 +1,4320 @@
+<?xml version="1.0"?>
+<rdf:RDF xmlns="http://purl.obolibrary.org/obo/ogms.owl#"
+     xml:base="http://purl.obolibrary.org/obo/ogms.owl"
+     xmlns:dc="http://purl.org/dc/elements/1.1/"
+     xmlns:obo="http://purl.obolibrary.org/obo/"
+     xmlns:owl="http://www.w3.org/2002/07/owl#"
+     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
+     xmlns:xml="http://www.w3.org/XML/1998/namespace"
+     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
+     xmlns:foaf="http://xmlns.com/foaf/0.1/"
+     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
+     xmlns:terms="http://purl.org/dc/terms/"
+     xmlns:protege="http://protege.stanford.edu/plugins/owl/protege#"
+     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#">
+    <owl:Ontology rdf:about="http://purl.obolibrary.org/obo/ogms.owl">
+        <owl:versionIRI rdf:resource="http://purl.obolibrary.org/obo/ogms/2021-08-19/ogms.owl"/>
+        <dc:creator>Alan Ruttenberg</dc:creator>
+        <dc:creator>Albert Goldfain</dc:creator>
+        <dc:creator>Anand Kumar</dc:creator>
+        <dc:creator>Barry Smith</dc:creator>
+        <dc:creator>Bill Hogan</dc:creator>
+        <dc:creator>Brian Aevermann</dc:creator>
+        <dc:creator>Cornelius Rosse</dc:creator>
+        <dc:creator>Daniel Merico</dc:creator>
+        <dc:creator>Jie Zheng</dc:creator>
+        <dc:creator>Lindsay Cowell</dc:creator>
+        <dc:creator>Richard Scheuermann</dc:creator>
+        <dc:creator>Sivaram Arabandi</dc:creator>
+        <dc:creator>Werner Ceusters</dc:creator>
+        <dc:date>2009-08-07</dc:date>
+        <dc:description xml:lang="en">The Ontology for General Medical Science (OGMS) is an ontology of entities involved in a clinical encounter. OGMS includes very general terms that are used across medical disciplines, including: &apos;disease&apos;, &apos;disorder&apos;, &apos;disease course&apos;, &apos;diagnosis&apos;, &apos;patient&apos;, and &apos;healthcare provider&apos;. OGMS uses the Basic Formal Ontology (BFO) as an upper-level ontology. The scope of OGMS is restricted to humans, but many terms can be applied to a variety of organisms. OGMS provides a formal theory of disease that can be further elaborated by specific disease ontologies. This theory is implemented using OWL-DL and OBO Relation Ontology relations and is available in OWL and OBO formats.
+
+OGMS is based on the papers Toward an Ontological Treatment of Disease and Diagnosis and On Carcinomas and Other Pathological Entities. The ontology attempts to address some of the issues raised at the Workshop on Ontology of Diseases (Dallas, TX) and the Signs, Symptoms, and Findings Workshop(Milan, Italy). OGMS was formerly called the clinical phenotype ontology. Terms from OGMS hang from the Basic Formal Ontology.</dc:description>
+        <dc:title>Ontology for General Medical Science</dc:title>
+        <terms:license>http://creativecommons.org/licenses/by/4.0/</terms:license>
+        <rdfs:comment xml:lang="en">The Ontology for General Medical Science (OGMS) is based on the papers Toward an Ontological Treatment of Disease and Diagnosis and On Carcinomas and Other Pathological Entities. The ontology attempts to address some of the issues raised at the Workshop on Ontology of Diseases (Dallas, TX). OGMS was formerly called the clinical phenotype ontology. Terms from OGMS hang from the Basic Formal Ontology.
+
+The latest version of OGMS is available at http://purl.obolibrary.org/obo/ogms.owl
+
+The OGMS developer site is https://github.com/OGMS/ogms
+
+If you are interested in participating in the development of OGMS, please send email to baeverma</rdfs:comment>
+        <owl:versionInfo rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2021-08-19</owl:versionInfo>
+    </owl:Ontology>
+    
+
+
+    <!-- 
+    ///////////////////////////////////////////////////////////////////////////////////////
+    //
+    // Annotation properties
+    //
+    ///////////////////////////////////////////////////////////////////////////////////////
+     -->
+
+    
+
+
+    <!-- http://protege.stanford.edu/plugins/owl/protege#defaultLanguage -->
+
+    <owl:AnnotationProperty rdf:about="http://protege.stanford.edu/plugins/owl/protege#defaultLanguage"/>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000179 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000179">
+        <obo:IAO_0000115 xml:lang="en">Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification.</obo:IAO_0000115>
+        <obo:IAO_0000232 xml:lang="en">Really of interest to developers only</obo:IAO_0000232>
+        <rdfs:label xml:lang="en">BFO OWL specification label</rdfs:label>
+        <rdfs:subPropertyOf rdf:resource="http://www.w3.org/2000/01/rdf-schema#label"/>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000180 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000180">
+        <obo:IAO_0000115 xml:lang="en">Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2</obo:IAO_0000115>
+        <obo:IAO_0000119>Person:Alan Ruttenberg</obo:IAO_0000119>
+        <obo:IAO_0000232 xml:lang="en">Really of interest to developers only</obo:IAO_0000232>
+        <rdfs:label xml:lang="en">BFO CLIF specification label</rdfs:label>
+        <rdfs:subPropertyOf rdf:resource="http://www.w3.org/2000/01/rdf-schema#label"/>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000111 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000111">
+        <obo:IAO_0000111 xml:lang="en">editor preferred term</obo:IAO_0000111>
+        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
+        <obo:IAO_0000115 xml:lang="en">The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English)</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">GROUP:OBI:&lt;http://purl.obolibrary.org/obo/obi&gt;</obo:IAO_0000119>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
+        <rdfs:label xml:lang="en">editor preferred term</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000112 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000112">
+        <obo:IAO_0000111 xml:lang="en">example of usage</obo:IAO_0000111>
+        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
+        <obo:IAO_0000115 xml:lang="en">A phrase describing how a term should be used and/or a citation to a work which uses it. May also include other kinds of examples that facilitate immediate understanding, such as widely know prototypes or instances of a class, or cases where a relation is said to hold.</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">GROUP:OBI:&lt;http://purl.obolibrary.org/obo/obi&gt;</obo:IAO_0000119>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
+        <rdfs:label xml:lang="en">example of usage</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000113 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000113">
+        <obo:IAO_0000111 xml:lang="en">in branch</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">An annotation property indicating which module the terms belong to. This is currently experimental and not implemented yet.</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">GROUP:OBI</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">OBI_0000277</obo:IAO_0000119>
+        <rdfs:label xml:lang="en">in branch</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000114 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000114">
+        <obo:IAO_0000111 xml:lang="en">has curation status</obo:IAO_0000111>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Bill Bug</obo:IAO_0000117>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Melanie Courtot</obo:IAO_0000117>
+        <rdfs:label xml:lang="en">has curation status</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000115 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115">
+        <obo:IAO_0000111 xml:lang="en">definition</obo:IAO_0000111>
+        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
+        <obo:IAO_0000115 xml:lang="en">The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions.</obo:IAO_0000115>
+        <obo:IAO_0000116 xml:lang="en">2012-04-05: 
+Barry Smith
+
+The official OBI definition, explaining the meaning of a class or property: &apos;Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions&apos;  is terrible.
+
+Can you fix to something like:
+
+A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property.
+
+Alan Ruttenberg
+
+Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can&apos;t be evaluated by those criteria. 
+
+On the specifics of the proposed definition:
+
+We don&apos;t have definitions of &apos;meaning&apos; or &apos;expression&apos; or &apos;property&apos;. For &apos;reference&apos; in the intended sense I think we use the term &apos;denotation&apos;. For &apos;expression&apos;, I think we you mean symbol, or identifier. For &apos;meaning&apos; it differs for class and property. For class we want documentation that let&apos;s the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let&apos;s the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The &apos;intended reader&apos; part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. 
+
+Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. 
+
+We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with.  </obo:IAO_0000116>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">GROUP:OBI:&lt;http://purl.obolibrary.org/obo/obi&gt;</obo:IAO_0000119>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
+        <rdfs:label xml:lang="en">definition</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000116 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000116">
+        <obo:IAO_0000111 xml:lang="en">editor note</obo:IAO_0000111>
+        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
+        <obo:IAO_0000115 xml:lang="en">An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology.</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">GROUP:OBI:&lt;http://purl.obofoundry.org/obo/obi&gt;</obo:IAO_0000119>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
+        <rdfs:label xml:lang="en">editor note</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000117 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117">
+        <obo:IAO_0000111 xml:lang="en">term editor</obo:IAO_0000111>
+        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
+        <obo:IAO_0000115 xml:lang="en">Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people</obo:IAO_0000115>
+        <obo:IAO_0000116 xml:lang="en">20110707, MC: label update to term editor and definition modified accordingly. See https://github.com/information-artifact-ontology/IAO/issues/115.</obo:IAO_0000116>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">GROUP:OBI:&lt;http://purl.obolibrary.org/obo/obi&gt;</obo:IAO_0000119>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
+        <rdfs:label xml:lang="en">term editor</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000118 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000118">
+        <obo:IAO_0000111 xml:lang="en">alternative term</obo:IAO_0000111>
+        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
+        <obo:IAO_0000115 xml:lang="en">An alternative name for a class or property which means the same thing as the preferred name (semantically equivalent)</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">GROUP:OBI:&lt;http://purl.obolibrary.org/obo/obi&gt;</obo:IAO_0000119>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
+        <rdfs:label xml:lang="en">alternative term</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000119 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000119">
+        <obo:IAO_0000111 xml:lang="en">definition source</obo:IAO_0000111>
+        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
+        <obo:IAO_0000115 xml:lang="en">Formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">Discussion on obo-discuss mailing-list, see http://bit.ly/hgm99w</obo:IAO_0000119>
+        <obo:IAO_0000119 xml:lang="en">GROUP:OBI:&lt;http://purl.obolibrary.org/obo/obi&gt;</obo:IAO_0000119>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
+        <rdfs:label xml:lang="en">definition source</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000231 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000231">
+        <obo:IAO_0000111 xml:lang="en">has obsolescence reason</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification.</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Melanie Courtot</obo:IAO_0000117>
+        <rdfs:label xml:lang="en">has obsolescence reason</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000232 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000232">
+        <obo:IAO_0000111 xml:lang="en">curator note</obo:IAO_0000111>
+        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
+        <obo:IAO_0000115 xml:lang="en">An administrative note of use for a curator but of no use for a user</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
+        <rdfs:label xml:lang="en">curator note</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000233 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000233">
+        <obo:IAO_0000111 xml:lang="en">term tracker item</obo:IAO_0000111>
+        <obo:IAO_0000112 xml:lang="en">the URI for an OBI Terms ticket at sourceforge, such as https://sourceforge.net/p/obi/obi-terms/772/</obo:IAO_0000112>
+        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
+        <obo:IAO_0000115 xml:lang="en">An IRI or similar locator for a request or discussion of an ontology term.</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg</obo:IAO_0000119>
+        <rdfs:comment xml:lang="en">The &apos;tracker item&apos; can associate a tracker with a specific ontology term.</rdfs:comment>
+        <rdfs:label xml:lang="en">term tracker item</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000234 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000234">
+        <obo:IAO_0000111 xml:lang="en">ontology term requester</obo:IAO_0000111>
+        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
+        <obo:IAO_0000115 xml:lang="en">The name of the person, project, or organization that motivated inclusion of an ontology term by requesting its addition.</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg</obo:IAO_0000119>
+        <rdfs:comment>The &apos;term requester&apos; can credit the person, organization or project who request the ontology term.</rdfs:comment>
+        <rdfs:label xml:lang="en">ontology term requester</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000411 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000411">
+        <obo:IAO_0000111 xml:lang="en">is denotator type</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">Relates an class defined in an ontology, to the type of it&apos;s denotator</obo:IAO_0000115>
+        <obo:IAO_0000116 xml:lang="en">In OWL 2 add AnnotationPropertyRange(&apos;is denotator type&apos; &apos;denotator type&apos;)</obo:IAO_0000116>
+        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
+        <rdfs:label xml:lang="en">is denotator type</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000412 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000412">
+        <obo:IAO_0000111 xml:lang="en">imported from</obo:IAO_0000111>
+        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
+        <obo:IAO_0000115 xml:lang="en">For external terms/classes, the ontology from which the term was imported</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Melanie Courtot</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">GROUP:OBI:&lt;http://purl.obolibrary.org/obo/obi&gt;</obo:IAO_0000119>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
+        <rdfs:label xml:lang="en">imported from</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000424 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000424">
+        <obo:IAO_0000111 xml:lang="en">expand expression to</obo:IAO_0000111>
+        <obo:IAO_0000112 xml:lang="en">ObjectProperty: RO_0002104
+Label: has plasma membrane part
+Annotations: IAO_0000424 &quot;http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.org/obo/owl/GO#GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)&quot;
+</obo:IAO_0000112>
+        <obo:IAO_0000115 xml:lang="en">A macro expansion tag applied to an object property (or possibly a data property)  which can be used by a macro-expansion engine to generate more complex expressions from simpler ones</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
+        <rdfs:label xml:lang="en">expand expression to</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000425 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000425">
+        <obo:IAO_0000111 xml:lang="en">expand assertion to</obo:IAO_0000111>
+        <obo:IAO_0000112 xml:lang="en">ObjectProperty: RO???
+Label: spatially disjoint from
+Annotations: expand_assertion_to &quot;DisjointClasses: (http://purl.obolibrary.org/obo/BFO_0000051 some ?X)  (http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)&quot;
+</obo:IAO_0000112>
+        <obo:IAO_0000115 xml:lang="en">A macro expansion tag applied to an annotation property which can be expanded into a more detailed axiom.</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
+        <rdfs:label xml:lang="en">expand assertion to</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000426 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000426">
+        <obo:IAO_0000111 xml:lang="en">first order logic expression</obo:IAO_0000111>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
+        <rdfs:label xml:lang="en">first order logic expression</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000427 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000427">
+        <obo:IAO_0000111 xml:lang="en">antisymmetric property</obo:IAO_0000111>
+        <obo:IAO_0000112 xml:lang="en">part_of antisymmetric property xsd:true</obo:IAO_0000112>
+        <obo:IAO_0000115 xml:lang="en">Use boolean value xsd:true to indicate that the property is an antisymmetric property</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
+        <rdfs:label xml:lang="en">antisymmetric property</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000589 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000589">
+        <obo:IAO_0000111 xml:lang="en">OBO foundry unique label</obo:IAO_0000111>
+        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
+        <obo:IAO_0000115 xml:lang="en">An alternative name for a class or property which is unique across the OBO Foundry.</obo:IAO_0000115>
+        <obo:IAO_0000116 xml:lang="en">The intended usage of that property is as follow: OBO foundry unique labels are automatically generated based on regular expressions provided by each ontology, so that SO could specify unique label = &apos;sequence &apos; + [label], etc. , MA could specify &apos;mouse + [label]&apos; etc. Upon importing terms, ontology developers can choose to use the &apos;OBO foundry unique label&apos; for an imported term or not. The same applies to tools .</obo:IAO_0000116>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Bjoern Peters</obo:IAO_0000117>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Chris Mungall</obo:IAO_0000117>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Melanie Courtot</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">GROUP:OBO Foundry &lt;http://obofoundry.org/&gt;</obo:IAO_0000119>
+        <rdfs:label xml:lang="en">OBO foundry unique label</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000596 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000596">
+        <obo:IAO_0000111 xml:lang="en">has ID digit count</obo:IAO_0000111>
+        <obo:IAO_0000112 xml:lang="en">Ontology: &lt;http://purl.obolibrary.org/obo/ro/idrange/&gt;
+  Annotations: 
+     &apos;has ID prefix&apos;: &quot;http://purl.obolibrary.org/obo/RO_&quot;
+     &apos;has ID digit count&apos; : 7,
+     rdfs:label &quot;RO id policy&quot;
+     &apos;has ID policy for&apos;: &quot;RO&quot;</obo:IAO_0000112>
+        <obo:IAO_0000115 xml:lang="en">Relates an ontology used to record id policy to the number of digits in the URI. The URI is: the &apos;has ID prefix&quot; annotation property value concatenated with an integer in the id range (left padded with &quot;0&quot;s to make this many digits)</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
+        <rdfs:label xml:lang="en">has ID digit count</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000597 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000597">
+        <obo:IAO_0000111 xml:lang="en">has ID range allocated</obo:IAO_0000111>
+        <obo:IAO_0000112 xml:lang="en">Datatype: idrange:1
+Annotations: &apos;has ID range allocated to&apos;: &quot;Chris Mungall&quot;
+EquivalentTo: xsd:integer[&gt; 2151 , &lt;= 2300]
+</obo:IAO_0000112>
+        <obo:IAO_0000115 xml:lang="en">Relates a datatype that encodes a range of integers to the name of the person or organization who can use those ids constructed in that range to define new terms</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
+        <rdfs:label xml:lang="en">has ID range allocated to</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000598 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000598">
+        <obo:IAO_0000111 xml:lang="en">has ID policy for</obo:IAO_0000111>
+        <obo:IAO_0000112 xml:lang="en">Ontology: &lt;http://purl.obolibrary.org/obo/ro/idrange/&gt;
+  Annotations: 
+     &apos;has ID prefix&apos;: &quot;http://purl.obolibrary.org/obo/RO_&quot;
+     &apos;has ID digit count&apos; : 7,
+     rdfs:label &quot;RO id policy&quot;
+     &apos;has ID policy for&apos;: &quot;RO&quot;</obo:IAO_0000112>
+        <obo:IAO_0000115 xml:lang="en">Relating an ontology used to record id policy to the ontology namespace whose policy it manages</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
+        <rdfs:label xml:lang="en">has ID policy for</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000599 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000599">
+        <obo:IAO_0000111 xml:lang="en">has ID prefix</obo:IAO_0000111>
+        <obo:IAO_0000112 xml:lang="en">Ontology: &lt;http://purl.obolibrary.org/obo/ro/idrange/&gt;
+  Annotations: 
+     &apos;has ID prefix&apos;: &quot;http://purl.obolibrary.org/obo/RO_&quot;
+     &apos;has ID digit count&apos; : 7,
+     rdfs:label &quot;RO id policy&quot;
+     &apos;has ID policy for&apos;: &quot;RO&quot;</obo:IAO_0000112>
+        <obo:IAO_0000115 xml:lang="en">Relates an ontology used to record id policy to a prefix concatenated with an integer in the id range (left padded with &quot;0&quot;s to make this many digits) to construct an ID for a term being created.</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
+        <rdfs:label xml:lang="en">has ID prefix</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000600 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000600">
+        <obo:IAO_0000111 xml:lang="en">elucidation</obo:IAO_0000111>
+        <obo:IAO_0000117 xml:lang="en">person:Alan Ruttenberg</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">Person:Barry Smith</obo:IAO_0000119>
+        <obo:IAO_0000600 xml:lang="en">Primitive terms in a highest-level ontology such as BFO are terms which are so basic to our understanding of reality that there is no way of defining them in a non-circular fashion. For these, therefore, we can provide only elucidations, supplemented by examples and by axioms</obo:IAO_0000600>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
+        <rdfs:label xml:lang="en">elucidation</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000601 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000601">
+        <obo:IAO_0000111 xml:lang="en">has associated axiom(nl)</obo:IAO_0000111>
+        <obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000119>
+        <obo:IAO_0000600 xml:lang="en">An axiom associated with a term expressed using natural language</obo:IAO_0000600>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
+        <rdfs:label xml:lang="en">has associated axiom(nl)</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000602 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000602">
+        <obo:IAO_0000111 xml:lang="en">has associated axiom(fol)</obo:IAO_0000111>
+        <obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000119>
+        <obo:IAO_0000600 xml:lang="en">An axiom expressed in first order logic using CLIF syntax</obo:IAO_0000600>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
+        <rdfs:label xml:lang="en">has associated axiom(fol)</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000603 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000603">
+        <obo:IAO_0000111 xml:lang="en">is allocated id range</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">Relates an ontology IRI to an (inclusive) range of IRIs in an OBO name space. The range is give as, e.g. &quot;IAO_0020000-IAO_0020999&quot;</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
+        <rdfs:comment xml:lang="en">Add as annotation triples in the granting ontology</rdfs:comment>
+        <rdfs:label xml:lang="en">is allocated id range</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000700 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000700">
+        <obo:IAO_0000111 xml:lang="en">has ontology root term</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root.</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">Nicolas Matentzoglu</obo:IAO_0000117>
+        <rdfs:label xml:lang="en">has ontology root term</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0006011 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0006011">
+        <obo:IAO_0000111 xml:lang="en">may be identical to</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">A annotation relationship between two terms in an ontology that may refer to the same (natural) type but where more evidence is required before terms are merged.</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
+        <obo:IAO_0000233 xml:lang="en">#40</obo:IAO_0000233>
+        <obo:IAO_0000234 xml:lang="en">VFB</obo:IAO_0000234>
+        <rdfs:comment xml:lang="en">Edges asserting this should be annotated with to record evidence supporting the assertion and its provenance.</rdfs:comment>
+        <rdfs:label xml:lang="en">may be identical to</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0006012 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0006012">
+        <obo:IAO_0000111 xml:lang="en">scheduled for obsoletion on or after</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">Used when the class or object is scheduled for obsoletion/deprecation on or after a particular date.</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">Chris Mungall, Jie Zheng</obo:IAO_0000117>
+        <obo:IAO_0000233 xml:lang="en">https://github.com/geneontology/go-ontology/issues/15532</obo:IAO_0000233>
+        <obo:IAO_0000233 xml:lang="en">https://github.com/information-artifact-ontology/ontology-metadata/issues/32</obo:IAO_0000233>
+        <obo:IAO_0000234 xml:lang="en">GO ontology</obo:IAO_0000234>
+        <rdfs:label xml:lang="en">scheduled for obsoletion on or after</rdfs:label>
+        <rdfs:range rdf:resource="http://www.w3.org/2001/XMLSchema#dateTime"/>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0010000 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0010000">
+        <obo:IAO_0000111 xml:lang="en">has axiom id</obo:IAO_0000111>
+        <obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000119>
+        <obo:IAO_0000600 xml:lang="en">A URI that is intended to be unique label for an axiom used for tracking change to the ontology. For an axiom expressed in different languages, each expression is given the same URI</obo:IAO_0000600>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
+        <rdfs:label xml:lang="en">has axiom label</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0100001 -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0100001">
+        <obo:IAO_0000111 xml:lang="en">term replaced by</obo:IAO_0000111>
+        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
+        <obo:IAO_0000115 xml:lang="en">Use on obsolete terms, relating the term to another term that can be used as a substitute</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000119>
+        <rdfs:comment xml:lang="en">Add as annotation triples in the granting ontology</rdfs:comment>
+        <rdfs:label xml:lang="en">term replaced by</rdfs:label>
+    </owl:AnnotationProperty>
+    
+
+
+    <!-- http://purl.org/dc/elements/1.1/contributor -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/contributor"/>
+    
+
+
+    <!-- http://purl.org/dc/elements/1.1/coverage -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/coverage"/>
+    
+
+
+    <!-- http://purl.org/dc/elements/1.1/creator -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/creator"/>
+    
+
+
+    <!-- http://purl.org/dc/elements/1.1/date -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/date"/>
+    
+
+
+    <!-- http://purl.org/dc/elements/1.1/description -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/description"/>
+    
+
+
+    <!-- http://purl.org/dc/elements/1.1/format -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/format"/>
+    
+
+
+    <!-- http://purl.org/dc/elements/1.1/identifier -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/identifier"/>
+    
+
+
+    <!-- http://purl.org/dc/elements/1.1/language -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/language"/>
+    
+
+
+    <!-- http://purl.org/dc/elements/1.1/member -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/member"/>
+    
+
+
+    <!-- http://purl.org/dc/elements/1.1/publisher -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/publisher"/>
+    
+
+
+    <!-- http://purl.org/dc/elements/1.1/relation -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/relation"/>
+    
+
+
+    <!-- http://purl.org/dc/elements/1.1/rights -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/rights"/>
+    
+
+
+    <!-- http://purl.org/dc/elements/1.1/source -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/source"/>
+    
+
+
+    <!-- http://purl.org/dc/elements/1.1/subject -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/subject"/>
+    
+
+
+    <!-- http://purl.org/dc/elements/1.1/title -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/title"/>
+    
+
+
+    <!-- http://purl.org/dc/elements/1.1/type -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/type"/>
+    
+
+
+    <!-- http://purl.org/dc/terms/license -->
+
+    <owl:AnnotationProperty rdf:about="http://purl.org/dc/terms/license"/>
+    
+
+
+    <!-- http://www.geneontology.org/formats/oboInOwl#created_by -->
+
+    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#created_by"/>
+    
+
+
+    <!-- http://www.geneontology.org/formats/oboInOwl#creation_date -->
+
+    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#creation_date"/>
+    
+
+
+    <!-- http://www.w3.org/2000/01/rdf-schema#isDefinedBy -->
+
+    <owl:AnnotationProperty rdf:about="http://www.w3.org/2000/01/rdf-schema#isDefinedBy"/>
+    
+
+
+    <!-- http://www.w3.org/2000/01/rdf-schema#seeAlso -->
+
+    <owl:AnnotationProperty rdf:about="http://www.w3.org/2000/01/rdf-schema#seeAlso"/>
+    
+
+
+    <!-- http://xmlns.com/foaf/0.1/homepage -->
+
+    <owl:AnnotationProperty rdf:about="http://xmlns.com/foaf/0.1/homepage"/>
+    
+
+
+    <!-- http://xmlns.com/foaf/0.1/mbox -->
+
+    <owl:AnnotationProperty rdf:about="http://xmlns.com/foaf/0.1/mbox"/>
+    
+
+
+    <!-- 
+    ///////////////////////////////////////////////////////////////////////////////////////
+    //
+    // Classes
+    //
+    ///////////////////////////////////////////////////////////////////////////////////////
+     -->
+
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000001 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000001">
+        <rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
+        <obo:BFO_0000179>entity</obo:BFO_0000179>
+        <obo:BFO_0000180>Entity</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">Julius Caesar</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">Verdi’s Requiem</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the Second World War</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">your body mass index</obo:IAO_0000112>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81</obo:IAO_0000116>
+        <obo:IAO_0000116 xml:lang="en">Entity doesn&apos;t have a closure axiom because the subclasses don&apos;t necessarily exhaust all possibilites. For example Werner Ceusters &apos;portions of reality&apos; include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, &apos;How to track absolutely everything&apos; at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf</obo:IAO_0000116>
+        <obo:IAO_0000600 xml:lang="en">An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])</obo:IAO_0000600>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">entity</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000001"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
+        <owl:annotatedTarget xml:lang="en">Entity doesn&apos;t have a closure axiom because the subclasses don&apos;t necessarily exhaust all possibilites. For example Werner Ceusters &apos;portions of reality&apos; include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, &apos;How to track absolutely everything&apos; at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000004"/>
+        <rdfs:comment>per discussion with Barry Smith</rdfs:comment>
+        <rdfs:seeAlso rdf:resource="http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000001"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/001-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000002 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000002">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000001"/>
+        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
+        <obo:BFO_0000179>continuant</obo:BFO_0000179>
+        <obo:BFO_0000180>Continuant</obo:BFO_0000180>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240</obo:IAO_0000116>
+        <obo:IAO_0000116 xml:lang="en">Continuant doesn&apos;t have a closure axiom because the subclasses don&apos;t necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster&apos;s other portions of reality, questions are raised as to whether universals are continuants</obo:IAO_0000116>
+        <obo:IAO_0000600 xml:lang="en">A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])</obo:IAO_0000600>
+        <obo:IAO_0000601 xml:lang="en">if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])</obo:IAO_0000601>
+        <obo:IAO_0000601 xml:lang="en">if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])</obo:IAO_0000601>
+        <obo:IAO_0000601 xml:lang="en">if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])</obo:IAO_0000601>
+        <obo:IAO_0000602>(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] </obo:IAO_0000602>
+        <obo:IAO_0000602>(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] </obo:IAO_0000602>
+        <obo:IAO_0000602>(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] </obo:IAO_0000602>
+        <obo:IAO_0000602>(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">continuant</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/008-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/011-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
+        <owl:annotatedTarget xml:lang="en">Continuant doesn&apos;t have a closure axiom because the subclasses don&apos;t necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster&apos;s other portions of reality, questions are raised as to whether universals are continuants</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000007"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/008-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
+        <owl:annotatedTarget xml:lang="en">if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/126-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
+        <owl:annotatedTarget xml:lang="en">if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/009-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
+        <owl:annotatedTarget xml:lang="en">if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/011-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/009-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/126-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000003 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000003">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000001"/>
+        <obo:BFO_0000179>occurrent</obo:BFO_0000179>
+        <obo:BFO_0000180>Occurrent</obo:BFO_0000180>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region</obo:IAO_0000116>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players.</obo:IAO_0000116>
+        <obo:IAO_0000116 xml:lang="en">Occurrent doesn&apos;t have a closure axiom because the subclasses don&apos;t necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process.</obo:IAO_0000116>
+        <obo:IAO_0000116>Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by &apos;spn[e]&apos; and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write &apos;spr[e]&apos; and `spl[e]&apos; respectively for the spread and spell of e, omitting mention of the frame.</obo:IAO_0000116>
+        <obo:IAO_0000600 xml:lang="en">An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])</obo:IAO_0000600>
+        <obo:IAO_0000601 xml:lang="en">Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])</obo:IAO_0000601>
+        <obo:IAO_0000601 xml:lang="en">b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])</obo:IAO_0000601>
+        <obo:IAO_0000602>(forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] </obo:IAO_0000602>
+        <obo:IAO_0000602>(forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">occurrent</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
+        <owl:annotatedTarget xml:lang="en">Occurrent doesn&apos;t have a closure axiom because the subclasses don&apos;t necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process.</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000006"/>
+        <rdfs:comment>per discussion with Barry Smith</rdfs:comment>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
+        <owl:annotatedTarget>Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by &apos;spn[e]&apos; and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write &apos;spr[e]&apos; and `spl[e]&apos; respectively for the spread and spell of e, omitting mention of the frame.</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000012"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/077-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
+        <owl:annotatedTarget xml:lang="en">Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/108-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
+        <owl:annotatedTarget xml:lang="en">b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/079-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/108-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/079-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000004 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000004">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
+        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
+        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
+        <obo:BFO_0000179>ic</obo:BFO_0000179>
+        <obo:BFO_0000180>IndependentContinuant</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">a chair</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">a heart</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">a leg</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">a molecule</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">a spatial region</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">an atom</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">an orchestra.</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">an organism</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the bottom right portion of a human torso</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the interior of your mouth</obo:IAO_0000112>
+        <obo:IAO_0000115 xml:lang="en">b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])</obo:IAO_0000115>
+        <obo:IAO_0000601 xml:lang="en">For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])</obo:IAO_0000601>
+        <obo:IAO_0000601 xml:lang="en">For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])</obo:IAO_0000601>
+        <obo:IAO_0000602>(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] </obo:IAO_0000602>
+        <obo:IAO_0000602>(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] </obo:IAO_0000602>
+        <obo:IAO_0000602>(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">independent continuant</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
+        <owl:annotatedTarget xml:lang="en">b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/017-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
+        <owl:annotatedTarget xml:lang="en">For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/134-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
+        <owl:annotatedTarget xml:lang="en">For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/018-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/134-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/018-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/017-002"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000006 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000006">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000141"/>
+        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000029"/>
+        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000140"/>
+        <obo:BFO_0000179>s-region</obo:BFO_0000179>
+        <obo:BFO_0000180>SpatialRegion</obo:BFO_0000180>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Spatial regions do not participate in processes.</obo:IAO_0000116>
+        <obo:IAO_0000116 xml:lang="en">Spatial region doesn&apos;t have a closure axiom because the subclasses don&apos;t exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn&apos;t overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional.</obo:IAO_0000116>
+        <obo:IAO_0000600 xml:lang="en">A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])</obo:IAO_0000600>
+        <obo:IAO_0000601 xml:lang="en">All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])</obo:IAO_0000601>
+        <obo:IAO_0000602>(forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] </obo:IAO_0000602>
+        <obo:IAO_0000602>(forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">spatial region</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
+        <owl:annotatedTarget xml:lang="en">Spatial region doesn&apos;t have a closure axiom because the subclasses don&apos;t exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn&apos;t overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional.</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000002"/>
+        <rdfs:comment>per discussion with Barry Smith</rdfs:comment>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/035-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
+        <owl:annotatedTarget xml:lang="en">All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/036-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/036-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/035-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000008 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000008">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
+        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
+        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
+        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000035"/>
+        <obo:BFO_0000179>t-region</obo:BFO_0000179>
+        <obo:BFO_0000180>TemporalRegion</obo:BFO_0000180>
+        <obo:IAO_0000116 xml:lang="en">Temporal region doesn&apos;t have a closure axiom because the subclasses don&apos;t exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn&apos;t overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional</obo:IAO_0000116>
+        <obo:IAO_0000600 xml:lang="en">A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001])</obo:IAO_0000600>
+        <obo:IAO_0000601 xml:lang="en">All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001])</obo:IAO_0000601>
+        <obo:IAO_0000601 xml:lang="en">Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002])</obo:IAO_0000601>
+        <obo:IAO_0000602>(forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002] </obo:IAO_0000602>
+        <obo:IAO_0000602>(forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001] </obo:IAO_0000602>
+        <obo:IAO_0000602>(forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">temporal region</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
+        <owl:annotatedTarget xml:lang="en">Temporal region doesn&apos;t have a closure axiom because the subclasses don&apos;t exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn&apos;t overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000003"/>
+        <rdfs:comment>per discussion with Barry Smith</rdfs:comment>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/100-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
+        <owl:annotatedTarget xml:lang="en">All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/101-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
+        <owl:annotatedTarget xml:lang="en">Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/119-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/119-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/101-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/100-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000009 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000009">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
+        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000028"/>
+        <obo:BFO_0000179>2d-s-region</obo:BFO_0000179>
+        <obo:BFO_0000180>TwoDimensionalSpatialRegion</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">an infinitely thin plane in space.</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the surface of a sphere-shaped part of space</obo:IAO_0000112>
+        <obo:IAO_0000600 xml:lang="en">A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001])</obo:IAO_0000600>
+        <obo:IAO_0000602>(forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">two-dimensional spatial region</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000009"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/039-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000009"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/039-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000011 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000011">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
+        <obo:BFO_0000179>st-region</obo:BFO_0000179>
+        <obo:BFO_0000180>SpatiotemporalRegion</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">the spatiotemporal region occupied by a human life</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the spatiotemporal region occupied by a process of cellular meiosis.</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the spatiotemporal region occupied by the development of a cancer tumor</obo:IAO_0000112>
+        <obo:IAO_0000600 xml:lang="en">A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001])</obo:IAO_0000600>
+        <obo:IAO_0000601 xml:lang="en">All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001])</obo:IAO_0000601>
+        <obo:IAO_0000601 xml:lang="en">Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001])</obo:IAO_0000601>
+        <obo:IAO_0000601 xml:lang="en">Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001])</obo:IAO_0000601>
+        <obo:IAO_0000601 xml:lang="en">Every spatiotemporal region occupies_spatiotemporal_region itself.</obo:IAO_0000601>
+        <obo:IAO_0000601 xml:lang="en">Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002])</obo:IAO_0000601>
+        <obo:IAO_0000602>(forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002] </obo:IAO_0000602>
+        <obo:IAO_0000602>(forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001] </obo:IAO_0000602>
+        <obo:IAO_0000602>(forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001] </obo:IAO_0000602>
+        <obo:IAO_0000602>(forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001] </obo:IAO_0000602>
+        <obo:IAO_0000602>(forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">spatiotemporal region</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/095-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
+        <owl:annotatedTarget xml:lang="en">All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/096-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
+        <owl:annotatedTarget xml:lang="en">Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/099-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
+        <owl:annotatedTarget xml:lang="en">Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/098-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
+        <owl:annotatedTarget xml:lang="en">Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/107-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/107-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/099-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/096-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/095-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/098-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000015 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000015">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
+        <obo:BFO_0000179>process</obo:BFO_0000179>
+        <obo:BFO_0000180>Process</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">a process of cell-division, \ a beating of the heart</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">a process of meiosis</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">a process of sleeping</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the course of a disease</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the flight of a bird</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the life of an organism</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">your process of aging.</obo:IAO_0000112>
+        <obo:IAO_0000115 xml:lang="en">p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])</obo:IAO_0000115>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)</obo:IAO_0000116>
+        <obo:IAO_0000602>(iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">process</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
+        <owl:annotatedTarget xml:lang="en">p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/083-003"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/083-003"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000016 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000016">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
+        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
+        <obo:BFO_0000179>disposition</obo:BFO_0000179>
+        <obo:BFO_0000180>Disposition</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">an atom of element X has the disposition to decay to an atom of element Y</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">certain people have a predisposition to colon cancer</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">children are innately disposed to categorize objects in certain ways.</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the cell wall is disposed to filter chemicals in endocytosis and exocytosis</obo:IAO_0000112>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type.</obo:IAO_0000116>
+        <obo:IAO_0000600 xml:lang="en">b is a disposition means: b is a realizable entity &amp; b’s bearer is some material entity &amp; b is such that if it ceases to exist, then its bearer is physically changed, &amp; b’s realization occurs when and because this bearer is in some special physical circumstances, &amp; this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])</obo:IAO_0000600>
+        <obo:IAO_0000601 xml:lang="en">If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])</obo:IAO_0000601>
+        <obo:IAO_0000602>(forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] </obo:IAO_0000602>
+        <obo:IAO_0000602>(forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">disposition</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">b is a disposition means: b is a realizable entity &amp; b’s bearer is some material entity &amp; b is such that if it ceases to exist, then its bearer is physically changed, &amp; b’s realization occurs when and because this bearer is in some special physical circumstances, &amp; this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/062-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
+        <owl:annotatedTarget xml:lang="en">If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/063-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/063-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/062-002"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000017 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000017">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
+        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
+        <obo:BFO_0000179>realizable</obo:BFO_0000179>
+        <obo:BFO_0000180>RealizableEntity</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">the disposition of this piece of metal to conduct electricity.</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the disposition of your blood to coagulate</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the function of your reproductive organs</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the role of being a doctor</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the role of this boundary to delineate where Utah and Colorado meet</obo:IAO_0000112>
+        <obo:IAO_0000600 xml:lang="en">To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])</obo:IAO_0000600>
+        <obo:IAO_0000601 xml:lang="en">All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])</obo:IAO_0000601>
+        <obo:IAO_0000602>(forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] </obo:IAO_0000602>
+        <obo:IAO_0000602>(forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">realizable entity</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/058-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
+        <owl:annotatedTarget xml:lang="en">All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/060-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/060-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/058-002"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000018 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000018">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
+        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000028"/>
+        <obo:BFO_0000179>0d-s-region</obo:BFO_0000179>
+        <obo:BFO_0000180>ZeroDimensionalSpatialRegion</obo:BFO_0000180>
+        <obo:IAO_0000600 xml:lang="en">A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001])</obo:IAO_0000600>
+        <obo:IAO_0000602>(forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">zero-dimensional spatial region</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000018"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/037-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000018"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/037-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000019 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000019">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
+        <obo:BFO_0000179>quality</obo:BFO_0000179>
+        <obo:BFO_0000180>Quality</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">the ambient temperature of this portion of air</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the color of a tomato</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the length of the circumference of your waist</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the mass of this piece of gold.</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the shape of your nose</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the shape of your nostril</obo:IAO_0000112>
+        <obo:IAO_0000600 xml:lang="en">a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])</obo:IAO_0000600>
+        <obo:IAO_0000601 xml:lang="en">If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])</obo:IAO_0000601>
+        <obo:IAO_0000602>(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] </obo:IAO_0000602>
+        <obo:IAO_0000602>(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">quality</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/055-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
+        <owl:annotatedTarget xml:lang="en">If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/105-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/055-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/105-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000020 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000020">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
+        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
+        <obo:BFO_0000179>sdc</obo:BFO_0000179>
+        <obo:BFO_0000180>SpecificallyDependentContinuant</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">of one-sided specifically dependent continuants: the mass of this tomato</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates.</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the disposition of this fish to decay</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the function of this heart: to pump blood</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the mutual dependence of proton donors and acceptors in chemical reactions [79</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the pink color of a medium rare piece of grilled filet mignon at its center</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the role of being a doctor</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the shape of this hole.</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the smell of this portion of mozzarella</obo:IAO_0000112>
+        <obo:IAO_0000115 xml:lang="en">b is a specifically dependent continuant = Def. b is a continuant &amp; there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])</obo:IAO_0000115>
+        <obo:IAO_0000116 xml:lang="en">Specifically dependent continuant doesn&apos;t have a closure axiom because the subclasses don&apos;t necessarily exhaust all possibilites. We&apos;re not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc.</obo:IAO_0000116>
+        <obo:IAO_0000602>(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">specifically dependent continuant</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
+        <owl:annotatedTarget xml:lang="en">b is a specifically dependent continuant = Def. b is a continuant &amp; there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/050-003"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
+        <owl:annotatedTarget xml:lang="en">Specifically dependent continuant doesn&apos;t have a closure axiom because the subclasses don&apos;t necessarily exhaust all possibilites. We&apos;re not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc.</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000005"/>
+        <rdfs:comment>per discussion with Barry Smith</rdfs:comment>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/050-003"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000023 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000023">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
+        <obo:BFO_0000179>role</obo:BFO_0000179>
+        <obo:BFO_0000180>Role</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married.</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the priest role</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the role of a boundary to demarcate two neighboring administrative territories</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the role of a building in serving as a military target</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the role of a stone in marking a property boundary</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the role of subject in a clinical trial</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the student role</obo:IAO_0000112>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role &amp; c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals –  professor, sergeant, nurse – only during certain phases in their lives.</obo:IAO_0000116>
+        <obo:IAO_0000600 xml:lang="en">b is a role means: b is a realizable entity &amp; b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be&amp; b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])</obo:IAO_0000600>
+        <obo:IAO_0000602>(forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">role</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">b is a role means: b is a realizable entity &amp; b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be&amp; b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/061-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/061-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000024 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000024">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
+        <obo:BFO_0000179>fiat-object-part</obo:BFO_0000179>
+        <obo:BFO_0000180>FiatObjectPart</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">or with divisions drawn by cognitive subjects for practical reasons, such as the division of a cake (before slicing) into (what will become) slices (and thus member parts of an object aggregate). However, this does not mean that fiat object parts are dependent for their existence on divisions or delineations effected by cognitive subjects. If, for example, it is correct to conceive geological layers of the Earth as fiat object parts of the Earth, then even though these layers were first delineated in recent times, still existed long before such delineation and what holds of these layers (for example that the oldest layers are also the lowest layers) did not begin to hold because of our acts of delineation.Treatment of material entity in BFOExamples viewed by some as problematic cases for the trichotomy of fiat object part, object, and object aggregate include: a mussel on (and attached to) a rock, a slime mold, a pizza, a cloud, a galaxy, a railway train with engine and multiple carriages, a clonal stand of quaking aspen, a bacterial community (biofilm), a broken femur. Note that, as Aristotle already clearly recognized, such problematic cases – which lie at or near the penumbra of instances defined by the categories in question – need not invalidate these categories. The existence of grey objects does not prove that there are not objects which are black and objects which are white; the existence of mules does not prove that there are not objects which are donkeys and objects which are horses. It does, however, show that the examples in question need to be addressed carefully in order to show how they can be fitted into the proposed scheme, for example by recognizing additional subdivisions [29</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the FMA:regional parts of an intact human body.</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the Western hemisphere of the Earth</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the division of the brain into regions</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the division of the planet into hemispheres</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the dorsal and ventral surfaces of the body</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the upper and lower lobes of the left lung</obo:IAO_0000112>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Most examples of fiat object parts are associated with theoretically drawn divisions</obo:IAO_0000116>
+        <obo:IAO_0000600 xml:lang="en">b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of  c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004])</obo:IAO_0000600>
+        <obo:IAO_0000602>(forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">fiat object part</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000024"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of  c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/027-004"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000024"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/027-004"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000026 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000026">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
+        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000028"/>
+        <obo:BFO_0000179>1d-s-region</obo:BFO_0000179>
+        <obo:BFO_0000180>OneDimensionalSpatialRegion</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">an edge of a cube-shaped portion of space.</obo:IAO_0000112>
+        <obo:IAO_0000600 xml:lang="en">A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001])</obo:IAO_0000600>
+        <obo:IAO_0000602>(forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">one-dimensional spatial region</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000026"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/038-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000026"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/038-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000027 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000027">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
+        <obo:BFO_0000179>object-aggregate</obo:BFO_0000179>
+        <obo:BFO_0000180>ObjectAggregate</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">a collection of cells in a blood biobank.</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">a swarm of bees is an aggregate of members who are linked together through natural bonds</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">a symphony orchestra</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">an organization is an aggregate whose member parts have roles of specific types (for example in a jazz band, a chess club, a football team)</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">defined by fiat: the aggregate of members of an organization</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">defined through physical attachment: the aggregate of atoms in a lump of granite</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">defined through physical containment: the aggregate of molecules of carbon dioxide in a sealed container</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">defined via attributive delimitations such as: the patients in this hospital</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the aggregate of bearings in a constant velocity axle joint</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the aggregate of blood cells in your body</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the nitrogen atoms in the atmosphere</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the restaurants in Palo Alto</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">your collection of Meissen ceramic plates.</obo:IAO_0000112>
+        <obo:IAO_0000116>An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects </obo:IAO_0000116>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: object aggregates may gain and lose parts while remaining numerically identical (one and the same individual) over time. This holds both for aggregates whose membership is determined naturally (the aggregate of cells in your body) and aggregates determined by fiat (a baseball team, a congressional committee).</obo:IAO_0000116>
+        <obo:IAO_0000119>ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, &apos;A Theory of Granular Partitions&apos;, in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158.</obo:IAO_0000119>
+        <obo:IAO_0000600 xml:lang="en">b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004])</obo:IAO_0000600>
+        <obo:IAO_0000602>(forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">object aggregate</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000027"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
+        <owl:annotatedTarget>An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000011"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000027"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
+        <owl:annotatedTarget>An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000301"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000027"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000119"/>
+        <owl:annotatedTarget>ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, &apos;A Theory of Granular Partitions&apos;, in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158.</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000300"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000027"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/025-004"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000027"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/025-004"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000028 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000028">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
+        <obo:BFO_0000179>3d-s-region</obo:BFO_0000179>
+        <obo:BFO_0000180>ThreeDimensionalSpatialRegion</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">a cube-shaped region of space</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">a sphere-shaped region of space,</obo:IAO_0000112>
+        <obo:IAO_0000600 xml:lang="en">A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001])</obo:IAO_0000600>
+        <obo:IAO_0000602>(forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">three-dimensional spatial region</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000028"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/040-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000028"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/040-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000029 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000029">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000141"/>
+        <obo:BFO_0000179>site</obo:BFO_0000179>
+        <obo:BFO_0000180>Site</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">Manhattan Canyon)</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">a hole in the interior of a portion of cheese</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">a rabbit hole</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">an air traffic control region defined in the airspace above an airport</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the Grand Canyon</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the Piazza San Marco</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the cockpit of an aircraft</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the hold of a ship</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the interior of a kangaroo pouch</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the interior of the trunk of your car</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the interior of your bedroom</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the interior of your office</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the interior of your refrigerator</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the lumen of your gut</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">your left nostril (a fiat part – the opening – of your left nasal cavity)</obo:IAO_0000112>
+        <obo:IAO_0000600 xml:lang="en">b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002])</obo:IAO_0000600>
+        <obo:IAO_0000602>(forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">site</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000029"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/034-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000029"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/034-002"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000030 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000030">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
+        <obo:BFO_0000179>object</obo:BFO_0000179>
+        <obo:BFO_0000180>Object</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">atom</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">cell</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">cells and organisms</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">engineered artifacts</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">grain of sand</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">molecule</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">organelle</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">organism</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">planet</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">solid portions of matter</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">star</obo:IAO_0000112>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: BFO rests on the presupposition that at multiple micro-, meso- and macroscopic scales reality exhibits certain stable, spatially separated or separable material units, combined or combinable into aggregates of various sorts (for example organisms into what are called ‘populations’). Such units play a central role in almost all domains of natural science from particle physics to cosmology. Many scientific laws govern the units in question, employing general terms (such as ‘molecule’ or ‘planet’) referring to the types and subtypes of units, and also to the types and subtypes of the processes through which such units develop and interact. The division of reality into such natural units is at the heart of biological science, as also is the fact that these units may form higher-level units (as cells form multicellular organisms) and that they may also form aggregates of units, for example as cells form portions of tissue and organs form families, herds, breeds, species, and so on. At the same time, the division of certain portions of reality into engineered units (manufactured artifacts) is the basis of modern industrial technology, which rests on the distributed mass production of engineered parts through division of labor and on their assembly into larger, compound units such as cars and laptops. The division of portions of reality into units is one starting point for the phenomenon of counting.</obo:IAO_0000116>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Each object is such that there are entities of which we can assert unproblematically that they lie in its interior, and other entities of which we can assert unproblematically that they lie in its exterior. This may not be so for entities lying at or near the boundary between the interior and exterior. This means that two objects – for example the two cells depicted in Figure 3 – may be such that there are material entities crossing their boundaries which belong determinately to neither cell. Something similar obtains in certain cases of conjoined twins (see below).</obo:IAO_0000116>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: To say that b is causally unified means: b is a material entity which is such that its material parts are tied together in such a way that, in environments typical for entities of the type in question,if c, a continuant part of b that is in the interior of b at t, is larger than a certain threshold size (which will be determined differently from case to case, depending on factors such as porosity of external cover) and is moved in space to be at t at a location on the exterior of the spatial region that had been occupied by b at t, then either b’s other parts will be moved in coordinated fashion or b will be damaged (be affected, for example, by breakage or tearing) in the interval between t and t.causal changes in one part of b can have consequences for other parts of b without the mediation of any entity that lies on the exterior of b. Material entities with no proper material parts would satisfy these conditions trivially. Candidate examples of types of causal unity for material entities of more complex sorts are as follows (this is not intended to be an exhaustive list):CU1: Causal unity via physical coveringHere the parts in the interior of the unified entity are combined together causally through a common membrane or other physical covering\. The latter points outwards toward and may serve a protective function in relation to what lies on the exterior of the entity [13, 47</obo:IAO_0000116>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: an object is a maximal causally unified material entity</obo:IAO_0000116>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: ‘objects’ are sometimes referred to as ‘grains’ [74</obo:IAO_0000116>
+        <obo:IAO_0000600 xml:lang="en">b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above &amp; is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001])</obo:IAO_0000600>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">object</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000030"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above &amp; is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/024-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000031 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000031">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
+        <obo:BFO_0000179>gdc</obo:BFO_0000179>
+        <obo:BFO_0000180>GenericallyDependentContinuant</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity.</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the pdf file on your laptop, the pdf file that is a copy thereof on my laptop</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule.</obo:IAO_0000112>
+        <obo:IAO_0000115 xml:lang="en">b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])</obo:IAO_0000115>
+        <obo:IAO_0000602>(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">generically dependent continuant</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
+        <owl:annotatedTarget xml:lang="en">b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/074-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/074-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000034 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000034">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
+        <obo:BFO_0000179>function</obo:BFO_0000179>
+        <obo:BFO_0000180>Function</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">the function of a hammer to drive in nails</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the function of a heart pacemaker to regulate the beating of a heart through electricity</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the function of amylase in saliva to break down starch into sugar</obo:IAO_0000112>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc.</obo:IAO_0000116>
+        <obo:IAO_0000600 xml:lang="en">A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])</obo:IAO_0000600>
+        <obo:IAO_0000602>(forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">function</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/064-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/064-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000035 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000035">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
+        <obo:BFO_0000179>p-boundary</obo:BFO_0000179>
+        <obo:BFO_0000180>ProcessBoundary</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">the boundary between the 2nd and 3rd year of your life.</obo:IAO_0000112>
+        <obo:IAO_0000115 xml:lang="en">p is a process boundary =Def. p is a temporal part of a process &amp; p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])</obo:IAO_0000115>
+        <obo:IAO_0000601 xml:lang="en">Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002])</obo:IAO_0000601>
+        <obo:IAO_0000602>(forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002] </obo:IAO_0000602>
+        <obo:IAO_0000602>(iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">process boundary</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000035"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
+        <owl:annotatedTarget xml:lang="en">p is a process boundary =Def. p is a temporal part of a process &amp; p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/084-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000035"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
+        <owl:annotatedTarget xml:lang="en">Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/085-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000035"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/085-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000035"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/084-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000038 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000038">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
+        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000148"/>
+        <obo:BFO_0000179>1d-t-region</obo:BFO_0000179>
+        <obo:BFO_0000180>OneDimensionalTemporalRegion</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">the temporal region during which a process occurs.</obo:IAO_0000112>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: A temporal interval is a special kind of one-dimensional temporal region, namely one that is self-connected (is without gaps or breaks).</obo:IAO_0000116>
+        <obo:IAO_0000600 xml:lang="en">A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001])</obo:IAO_0000600>
+        <obo:IAO_0000602>(forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">one-dimensional temporal region</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000038"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/103-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000038"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/103-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000040 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000040">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
+        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000141"/>
+        <obo:BFO_0000179>material</obo:BFO_0000179>
+        <obo:BFO_0000180>MaterialEntity</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">a flame</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">a forest fire</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">a human being</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">a hurricane</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">a photon</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">a puff of smoke</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">a sea wave</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">a tornado</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">an aggregate of human beings.</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">an energy wave</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">an epidemic</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the undetached arm of a human being</obo:IAO_0000112>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60</obo:IAO_0000116>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity.</obo:IAO_0000116>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here.</obo:IAO_0000116>
+        <obo:IAO_0000600 xml:lang="en">A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])</obo:IAO_0000600>
+        <obo:IAO_0000601 xml:lang="en">Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])</obo:IAO_0000601>
+        <obo:IAO_0000601 xml:lang="en">every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])</obo:IAO_0000601>
+        <obo:IAO_0000602>(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] </obo:IAO_0000602>
+        <obo:IAO_0000602>(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] </obo:IAO_0000602>
+        <obo:IAO_0000602>(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">material entity</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/019-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
+        <owl:annotatedTarget xml:lang="en">Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/020-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
+        <owl:annotatedTarget xml:lang="en">every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/021-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/019-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/021-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/020-002"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000140 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000140">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000141"/>
+        <obo:BFO_0000179>cf-boundary</obo:BFO_0000179>
+        <obo:BFO_0000180>ContinuantFiatBoundary</obo:BFO_0000180>
+        <obo:IAO_0000115 xml:lang="en">b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])</obo:IAO_0000115>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: In BFO 1.1 the assumption was made that the external surface of a material entity such as a cell could be treated as if it were a boundary in the mathematical sense. The new document propounds the view that when we talk about external surfaces of material objects in this way then we are talking about something fiat. To be dealt with in a future version: fiat boundaries at different levels of granularity.More generally, the focus in discussion of boundaries in BFO 2.0 is now on fiat boundaries, which means: boundaries for which there is no assumption that they coincide with physical discontinuities. The ontology of boundaries becomes more closely allied with the ontology of regions.</obo:IAO_0000116>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: a continuant fiat boundary is a boundary of some material entity (for example: the plane separating the Northern and Southern hemispheres; the North Pole), or it is a boundary of some immaterial entity (for example of some portion of airspace). Three basic kinds of continuant fiat boundary can be distinguished (together with various combination kinds [29</obo:IAO_0000116>
+        <obo:IAO_0000116 xml:lang="en">Continuant fiat boundary doesn&apos;t have a closure axiom because the subclasses don&apos;t necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn&apos;t overlap it. The situation is analogous to temporal and spatial regions.</obo:IAO_0000116>
+        <obo:IAO_0000601 xml:lang="en">Every continuant fiat boundary is located at some spatial region at every time at which it exists</obo:IAO_0000601>
+        <obo:IAO_0000602>(iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">continuant fiat boundary</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000140"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
+        <owl:annotatedTarget xml:lang="en">b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/029-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000140"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
+        <owl:annotatedTarget xml:lang="en">Continuant fiat boundary doesn&apos;t have a closure axiom because the subclasses don&apos;t necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn&apos;t overlap it. The situation is analogous to temporal and spatial regions.</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000008"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000140"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/029-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000141 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000141">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
+        <obo:BFO_0000179>immaterial</obo:BFO_0000179>
+        <obo:BFO_0000180>ImmaterialEntity</obo:BFO_0000180>
+        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10</obo:IAO_0000116>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">immaterial entity</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000142 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000142">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000140"/>
+        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000146"/>
+        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000147"/>
+        <obo:BFO_0000179>1d-cf-boundary</obo:BFO_0000179>
+        <obo:BFO_0000180>OneDimensionalContinuantFiatBoundary</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">The Equator</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">all geopolitical boundaries</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">all lines of latitude and longitude</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the line separating the outer surface of the mucosa of the lower lip from the outer surface of the skin of the chin.</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the median sulcus of your tongue</obo:IAO_0000112>
+        <obo:IAO_0000600 xml:lang="en">a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001])</obo:IAO_0000600>
+        <obo:IAO_0000602>(iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">one-dimensional continuant fiat boundary</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000142"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/032-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000142"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/032-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000144 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000144">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
+        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000182"/>
+        <obo:BFO_0000179>process-profile</obo:BFO_0000179>
+        <obo:BFO_0000180>ProcessProfile</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">On a somewhat higher level of complexity are what we shall call rate process profiles, which are the targets of selective abstraction focused not on determinate quality magnitudes plotted over time, but rather on certain ratios between these magnitudes and elapsed times. A speed process profile, for example, is represented by a graph plotting against time the ratio of distance covered per unit of time. Since rates may change, and since such changes, too, may have rates of change, we have to deal here with a hierarchy of process profile universals at successive levels</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">One important sub-family of rate process profiles is illustrated by the beat or frequency profiles of cyclical processes, illustrated by the 60 beats per minute beating process of John’s heart, or the 120 beats per minute drumming process involved in one of John’s performances in a rock band, and so on. Each such process includes what we shall call a beat process profile instance as part, a subtype of rate process profile in which the salient ratio is not distance covered but rather number of beat cycles per unit of time. Each beat process profile instance instantiates the determinable universal beat process profile. But it also instantiates multiple more specialized universals at lower levels of generality, selected from   rate process profilebeat process profileregular beat process profile3 bpm beat process profile4 bpm beat process profileirregular beat process profileincreasing beat process profileand so on.In the case of a regular beat process profile, a rate can be assigned in the simplest possible fashion by dividing the number of cycles by the length of the temporal region occupied by the beating process profile as a whole. Irregular process profiles of this sort, for example as identified in the clinic, or in the readings on an aircraft instrument panel, are often of diagnostic significance.</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">The simplest type of process profiles are what we shall call ‘quality process profiles’, which are the process profiles which serve as the foci of the sort of selective abstraction that is involved when measurements are made of changes in single qualities, as illustrated, for example, by process profiles of mass, temperature, aortic pressure, and so on.</obo:IAO_0000112>
+        <obo:IAO_0000115 xml:lang="en">b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])</obo:IAO_0000115>
+        <obo:IAO_0000600 xml:lang="en">b process_profile_of c holds when b proper_occurrent_part_of c&amp; there is some proper_occurrent_part d of c which has no parts in common with b &amp; is mutually dependent on b&amp; is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005])</obo:IAO_0000600>
+        <obo:IAO_0000602>(forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005] </obo:IAO_0000602>
+        <obo:IAO_0000602>(iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">process profile</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000144"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
+        <owl:annotatedTarget xml:lang="en">b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/093-002"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000144"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">b process_profile_of c holds when b proper_occurrent_part_of c&amp; there is some proper_occurrent_part d of c which has no parts in common with b &amp; is mutually dependent on b&amp; is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/094-005"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000144"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/094-005"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000144"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/093-002"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000145 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000145">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
+        <obo:BFO_0000179>r-quality</obo:BFO_0000179>
+        <obo:BFO_0000180>RelationalQuality</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married.</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">a marriage bond, an instance of requited love, an obligation between one person and another.</obo:IAO_0000112>
+        <obo:IAO_0000115 xml:lang="en">b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t &amp; b quality_of d at t. (axiom label in BFO2 Reference: [057-001])</obo:IAO_0000115>
+        <obo:IAO_0000602>(iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">relational quality</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000145"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
+        <owl:annotatedTarget xml:lang="en">b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t &amp; b quality_of d at t. (axiom label in BFO2 Reference: [057-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/057-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000145"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/057-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000146 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000146">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000140"/>
+        <obo:BFO_0000179>2d-cf-boundary</obo:BFO_0000179>
+        <obo:BFO_0000180>TwoDimensionalContinuantFiatBoundary</obo:BFO_0000180>
+        <obo:IAO_0000600 xml:lang="en">a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001])</obo:IAO_0000600>
+        <obo:IAO_0000602>(iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">two-dimensional continuant fiat boundary</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000146"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/033-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000146"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/033-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000147 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000147">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000140"/>
+        <obo:BFO_0000179>0d-cf-boundary</obo:BFO_0000179>
+        <obo:BFO_0000180>ZeroDimensionalContinuantFiatBoundary</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">the geographic North Pole</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the point of origin of some spatial coordinate system.</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet</obo:IAO_0000112>
+        <obo:IAO_0000116 xml:lang="en">zero dimension continuant fiat boundaries are not spatial points. Considering the example &apos;the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet&apos; : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona.</obo:IAO_0000116>
+        <obo:IAO_0000600 xml:lang="en">a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001])</obo:IAO_0000600>
+        <obo:IAO_0000602>(iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">zero-dimensional continuant fiat boundary</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000147"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
+        <owl:annotatedTarget xml:lang="en">zero dimension continuant fiat boundaries are not spatial points. Considering the example &apos;the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet&apos; : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona.</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000001"/>
+        <rdfs:comment>requested by Melanie Courtot</rdfs:comment>
+        <rdfs:seeAlso rdf:resource="https://groups.google.com/d/msg/bfo-owl-devel/s9Uug5QmAws/ZDRnpiIi_TUJ"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000147"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/031-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000147"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/031-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000148 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000148">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
+        <obo:BFO_0000179>0d-t-region</obo:BFO_0000179>
+        <obo:BFO_0000180>ZeroDimensionalTemporalRegion</obo:BFO_0000180>
+        <obo:IAO_0000112 xml:lang="en">a temporal region that is occupied by a process boundary</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">right now</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the moment at which a child is born</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the moment at which a finger is detached in an industrial accident</obo:IAO_0000112>
+        <obo:IAO_0000112 xml:lang="en">the moment of death.</obo:IAO_0000112>
+        <obo:IAO_0000118 xml:lang="en">temporal instant.</obo:IAO_0000118>
+        <obo:IAO_0000600 xml:lang="en">A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001])</obo:IAO_0000600>
+        <obo:IAO_0000602>(forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001] </obo:IAO_0000602>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">zero-dimensional temporal region</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000148"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/102-001"/>
+    </owl:Axiom>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000148"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
+        <owl:annotatedTarget>(forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001] </owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/102-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/BFO_0000182 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000182">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
+        <obo:BFO_0000179>history</obo:BFO_0000179>
+        <obo:BFO_0000180>History</obo:BFO_0000180>
+        <obo:IAO_0000600 xml:lang="en">A history is a process that is the sum of the totality of processes taking place in the spatiotemporal region occupied by a material entity or site, including processes on the surface of the entity or within the cavities to which it serves as host. (axiom label in BFO2 Reference: [138-001])</obo:IAO_0000600>
+        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
+        <rdfs:label xml:lang="en">history</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000182"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
+        <owl:annotatedTarget xml:lang="en">A history is a process that is the sum of the totality of processes taking place in the spatiotemporal region occupied by a material entity or site, including processes on the surface of the entity or within the cavities to which it serves as host. (axiom label in BFO2 Reference: [138-001])</owl:annotatedTarget>
+        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/138-001"/>
+    </owl:Axiom>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000027 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000027">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
+        <obo:IAO_0000111 xml:lang="en">data item</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements.</obo:IAO_0000115>
+        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
+        <rdfs:label xml:lang="en">data item</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000030 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000030">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
+        <obo:IAO_0000111 xml:lang="en">information content entity</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">A generically dependent continuant that is about some thing.</obo:IAO_0000115>
+        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
+        <rdfs:label xml:lang="en">information content entity</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000033 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000033">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
+        <obo:IAO_0000115 xml:lang="en">An information content entity whose concretizations indicate to their bearer how to realize them in a process.</obo:IAO_0000115>
+        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
+        <rdfs:label xml:lang="en">directive information entity</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000078 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000078">
+        <owl:equivalentClass>
+            <owl:Class>
+                <owl:oneOf rdf:parseType="Collection">
+                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000002"/>
+                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000120"/>
+                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000121"/>
+                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000122"/>
+                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000123"/>
+                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000124"/>
+                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000125"/>
+                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000423"/>
+                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000428"/>
+                </owl:oneOf>
+            </owl:Class>
+        </owl:equivalentClass>
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000102"/>
+        <obo:IAO_0000111 xml:lang="en">curation status specification</obo:IAO_0000111>
+        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
+        <obo:IAO_0000115 xml:lang="en">The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.</obo:IAO_0000115>
+        <obo:IAO_0000116 xml:lang="en">Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting)</obo:IAO_0000116>
+        <obo:IAO_0000117 xml:lang="en">PERSON:Bill Bug</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">GROUP:OBI:&lt;http://purl.obolibrary.org/obo/obi&gt;</obo:IAO_0000119>
+        <obo:IAO_0000119 xml:lang="en">OBI_0000266</obo:IAO_0000119>
+        <rdfs:label xml:lang="en">curation status specification</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000102 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000102">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
+        <obo:IAO_0000111 xml:lang="en">data about an ontology part</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">Data about an ontology part is a data item about a part of an ontology, for example a term</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
+        <rdfs:label xml:lang="en">data about an ontology part</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000225 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000225">
+        <owl:equivalentClass>
+            <owl:Class>
+                <owl:oneOf rdf:parseType="Collection">
+                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000103"/>
+                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000226"/>
+                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000227"/>
+                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000228"/>
+                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000229"/>
+                </owl:oneOf>
+            </owl:Class>
+        </owl:equivalentClass>
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000102"/>
+        <obo:IAO_0000111 xml:lang="en">obsolescence reason specification</obo:IAO_0000111>
+        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
+        <obo:IAO_0000115 xml:lang="en">The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.</obo:IAO_0000115>
+        <obo:IAO_0000116 xml:lang="en">The creation of this class has been inspired in part by Werner Ceusters&apos; paper, Applying evolutionary terminology auditing to the Gene Ontology.</obo:IAO_0000116>
+        <obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
+        <obo:IAO_0000117 xml:lang="en">PERSON: Melanie Courtot</obo:IAO_0000117>
+        <rdfs:label xml:lang="en">obsolescence reason specification</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000409 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000409">
+        <owl:equivalentClass>
+            <owl:Class>
+                <owl:oneOf rdf:parseType="Collection">
+                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000410"/>
+                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000420"/>
+                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000421"/>
+                </owl:oneOf>
+            </owl:Class>
+        </owl:equivalentClass>
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000102"/>
+        <obo:IAO_0000111 xml:lang="en">denotator type</obo:IAO_0000111>
+        <obo:IAO_0000112 xml:lang="en">The Basic Formal Ontology ontology makes a distinction between Universals and defined classes, where the formal are &quot;natural kinds&quot; and the latter arbitrary collections of entities.</obo:IAO_0000112>
+        <obo:IAO_0000115 xml:lang="en">A denotator type indicates how a term should be interpreted from an ontological perspective.</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">Barry Smith, Werner Ceusters</obo:IAO_0000119>
+        <rdfs:label xml:lang="en">denotator type</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000000 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000000">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000102"/>
+        <obo:IAO_0000111 xml:lang="en">ontology module</obo:IAO_0000111>
+        <obo:IAO_0000116 xml:lang="en">I have placed this under &apos;data about an ontology part&apos;, but this can be discussed. I think this is OK if &apos;part&apos; is interpreted reflexively, as an ontology module is the whole ontology rather than part of it.</obo:IAO_0000116>
+        <obo:IAO_0000118 xml:lang="en">ontology file</obo:IAO_0000118>
+        <obo:IAO_0000232 xml:lang="en">This class and it&apos;s subclasses are applied to OWL ontologies. Using an rdf:type triple will result in problems with OWL-DL. I propose that dcterms:type is instead used to connect an ontology URI with a class from this hierarchy. The class hierarchy is not disjoint, so multiple assertions can be made about a single ontology.</obo:IAO_0000232>
+        <rdfs:label xml:lang="en">ontology module</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000001 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000001">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
+        <obo:IAO_0000111 xml:lang="en">base ontology module</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">An ontology module that comprises only of asserted axioms local to the ontology, excludes import directives, and excludes axioms or declarations from external ontologies.</obo:IAO_0000115>
+        <rdfs:label xml:lang="en">base ontology module</rdfs:label>
+        <rdfs:seeAlso rdf:resource="https://github.com/INCATools/ontology-starter-kit/issues/50"/>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000002 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000002">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
+        <obo:IAO_0000111 xml:lang="en">editors ontology module</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">An ontology module that is intended to be directly edited, typically managed in source control, and typically not intended for direct consumption by end-users.</obo:IAO_0000115>
+        <obo:IAO_0000118 xml:lang="en">source ontology module</obo:IAO_0000118>
+        <rdfs:label xml:lang="en">editors ontology module</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000003 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000003">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
+        <obo:IAO_0000111 xml:lang="en">main release ontology module</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">An ontology module that is intended to be the primary release product and the one consumed by the majority of tools.</obo:IAO_0000115>
+        <obo:IAO_0000116 xml:lang="en">TODO: Add logical axioms that state that a main release ontology module is derived from (directly or indirectly) an editors module</obo:IAO_0000116>
+        <rdfs:label xml:lang="en">main release ontology module</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000004 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000004">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
+        <obo:IAO_0000111 xml:lang="en">bridge ontology module</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">An ontology module that consists entirely of axioms that connect or bridge two distinct ontology modules. For example, the Uberon-to-ZFA bridge module.</obo:IAO_0000115>
+        <rdfs:label xml:lang="en">bridge ontology module</rdfs:label>
+        <rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/inter-anatomy-ontology-bridge-ontologies"/>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000005 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000005">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
+        <obo:IAO_0000111 xml:lang="en">import ontology module</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">A subset ontology module that is intended to be imported from another ontology.</obo:IAO_0000115>
+        <obo:IAO_0000116 xml:lang="en">TODO: add axioms that indicate this is the output of a module extraction process.</obo:IAO_0000116>
+        <obo:IAO_0000118 xml:lang="en">import file</obo:IAO_0000118>
+        <rdfs:label xml:lang="en">import ontology module</rdfs:label>
+        <rdfs:seeAlso rdf:resource="http://robot.obolibrary.org/extract"/>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000006 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000006">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
+        <obo:IAO_0000111 xml:lang="en">subset ontology module</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">An ontology module that is extracted from a main ontology module and includes only a subset of entities or axioms.</obo:IAO_0000115>
+        <obo:IAO_0000118 xml:lang="en">ontology slim</obo:IAO_0000118>
+        <obo:IAO_0000118 xml:lang="en">subset ontology</obo:IAO_0000118>
+        <rdfs:label xml:lang="en">subset ontology module</rdfs:label>
+        <rdfs:seeAlso rdf:resource="http://robot.obolibrary.org/filter"/>
+        <rdfs:seeAlso rdf:resource="http://www.geneontology.org/page/go-slim-and-subset-guide"/>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000007 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000007">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
+        <obo:IAO_0000111 xml:lang="en">curation subset ontology module</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">A subset ontology that is intended as a whitelist for curators using the ontology. Such a subset will exclude classes that curators should not use for curation.</obo:IAO_0000115>
+        <rdfs:label xml:lang="en">curation subset ontology module</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000008 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000008">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
+        <obo:IAO_0000111 xml:lang="en">analysis ontology module</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">An ontology module that is intended for usage in analysis or discovery applications.</obo:IAO_0000115>
+        <rdfs:label xml:lang="en">analysis subset ontology module</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000009 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000009">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
+        <obo:IAO_0000111 xml:lang="en">single layer ontology module</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">A subset ontology that is largely comprised of a single layer or strata in an ontology class hierarchy. The purpose is typically for rolling up for visualization. The classes in the layer need not be disjoint.</obo:IAO_0000115>
+        <obo:IAO_0000118 xml:lang="en">ribbon subset</obo:IAO_0000118>
+        <rdfs:label xml:lang="en">single layer subset ontology module</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000010 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000010">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
+        <obo:IAO_0000111 xml:lang="en">exclusion subset ontology module</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">A subset of an ontology that is intended to be excluded for some purpose. For example, a blacklist of classes.</obo:IAO_0000115>
+        <obo:IAO_0000118 xml:lang="en">antislim</obo:IAO_0000118>
+        <rdfs:label xml:lang="en">exclusion subset ontology module</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000011 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000011">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000005"/>
+        <obo:IAO_0000111 xml:lang="en">external import ontology module</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">An imported ontology module that is derived from an external ontology. Derivation methods include the OWLAPI SLME approach.</obo:IAO_0000115>
+        <obo:IAO_0000118 xml:lang="en">external import</obo:IAO_0000118>
+        <rdfs:label xml:lang="en">external import ontology module</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000012 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000012">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
+        <obo:IAO_0000111 xml:lang="en">species subset ontology module</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">A subset ontology that is crafted to either include or exclude a taxonomic grouping of species.</obo:IAO_0000115>
+        <obo:IAO_0000118 xml:lang="en">taxon subset</obo:IAO_0000118>
+        <rdfs:label xml:lang="en">species subset ontology module</rdfs:label>
+        <rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/Taxon-constraints"/>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000013 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000013">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
+        <obo:IAO_0000111 xml:lang="en">reasoned ontology module</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">An ontology module that contains axioms generated by a reasoner. The generated axioms are typically direct SubClassOf axioms, but other possibilities are available.</obo:IAO_0000115>
+        <rdfs:label xml:lang="en">reasoned ontology module</rdfs:label>
+        <rdfs:seeAlso rdf:resource="http://robot.obolibrary.org/reason"/>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000014 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000014">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
+        <obo:IAO_0000111 xml:lang="en">generated ontology module</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">An ontology module that is automatically generated, for example via a SPARQL query or via template and a CSV.</obo:IAO_0000115>
+        <obo:IAO_0000116 xml:lang="en">TODO: Add axioms (using PROV-O?) that indicate this is the output-of some reasoning process</obo:IAO_0000116>
+        <rdfs:label xml:lang="en">generated ontology module</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000015 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000015">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000014"/>
+        <obo:IAO_0000111 xml:lang="en">template generated ontology module</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">An ontology module that is automatically generated from a template specification and fillers for slots in that template.</obo:IAO_0000115>
+        <rdfs:label xml:lang="en">template generated ontology module</rdfs:label>
+        <rdfs:seeAlso rdf:resource="http://robot.obolibrary.org/template"/>
+        <rdfs:seeAlso rdf:resource="https://doi.org/10.1186/s13326-017-0126-0"/>
+        <rdfs:seeAlso rdf:resource="https://github.com/dosumis/dead_simple_owl_design_patterns/"/>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000016 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000016">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000004"/>
+        <obo:IAO_0000111 xml:lang="en">taxonomic bridge ontology module</obo:IAO_0000111>
+        <rdfs:label xml:lang="en">taxonomic bridge ontology module</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000017 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000017">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
+        <obo:IAO_0000111 xml:lang="en">ontology module subsetted by expressivity</obo:IAO_0000111>
+        <rdfs:label xml:lang="en">ontology module subsetted by expressivity</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000018 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000018">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000017"/>
+        <obo:IAO_0000111 xml:lang="en">obo basic subset ontology module</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">A subset ontology that is designed for basic applications to continue to make certain simplifying assumptions; many of these simplifying assumptions were based on the initial version of the Gene Ontology, and have become enshrined in many popular and useful tools such as term enrichment tools.
+
+Examples of such assumptions include: traversing the ontology graph ignoring relationship types using a naive algorithm will not lead to cycles (i.e. the ontology is a DAG); every referenced term is declared in the ontology (i.e. there are no dangling clauses).
+
+An ontology is OBO Basic if and only if it has the following characteristics:
+DAG
+Unidirectional
+No Dangling Clauses
+Fully Asserted
+Fully Labeled
+No equivalence axioms
+Singly labeled edges
+No qualifier lists
+No disjointness axioms
+No owl-axioms header
+No imports</obo:IAO_0000115>
+        <rdfs:label xml:lang="en">obo basic subset ontology module</rdfs:label>
+        <rdfs:seeAlso rdf:resource="http://owlcollab.github.io/oboformat/doc/obo-syntax.html#6.2"/>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000019 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000019">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000017"/>
+        <obo:IAO_0000111 xml:lang="en">ontology module subsetted by OWL profile</obo:IAO_0000111>
+        <rdfs:label xml:lang="en">ontology module subsetted by OWL profile</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_8000020 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000020">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000019"/>
+        <obo:IAO_0000111 xml:lang="en">EL++ ontology module</obo:IAO_0000111>
+        <rdfs:label xml:lang="en">EL++ ontology module</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IDO_0000504 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IDO_0000504">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000045"/>
+        <obo:IAO_0000115 xml:lang="en">An infection that is clinically abnormal.</obo:IAO_0000115>
+        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ido.owl"/>
+        <rdfs:label xml:lang="en">infectious disorder</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IDO_0000586 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IDO_0000586">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
+        <obo:IAO_0000115 xml:lang="en">A part of an extended organism that itself has as part a population of one or more infectious agents and that (1) exists as a result of processes initiated by members of the infectious agent population and is (2) clinically abnormal in virtue of the presence of this infectious agent population, or (3) has a disposition to bring clinical abnormality to immunocompetent organisms of the same Species as the host (the organism corresponding to the extended organism) through transmission of a member or offspring of a member of the infectious agent population.</obo:IAO_0000115>
+        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ido.owl"/>
+        <rdfs:label xml:lang="en">infection</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IDO_0000630 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IDO_0000630">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IDO_0000586"/>
+        <obo:IAO_0000115 xml:lang="en">An infection resulting from a transmission process that unfolds in a hospital.</obo:IAO_0000115>
+        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ido.owl"/>
+        <rdfs:label xml:lang="en">hospital-acquired infection</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OBI_0000011 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000011">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
+        <obo:IAO_0000115 xml:lang="en">A process that realizes a plan which is the concretization of a plan specification.</obo:IAO_0000115>
+        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
+        <rdfs:label xml:lang="en">planned process</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OBI_0000278 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000278">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
+        <obo:IAO_0000115 xml:lang="en">a part of an occurrence of a disease process which is associated with position in the normal progression of the disease</obo:IAO_0000115>
+        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
+        <rdfs:label xml:lang="en">disease stage</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000014 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000014">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000123"/>
+        <obo:IAO_0000115 xml:lang="en">A representation that is either the output of a clinical history taking or a physical examination or an image finding, or some combination thereof.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2010-07-19T10:18:02Z</obo:IAO_0000232>
+        <rdfs:label>clinical finding</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000015 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000015">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000123"/>
+        <obo:IAO_0000115 xml:lang="en">A series of statements representing health-relevant qualities of a patient and of a patient&apos;s family.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2010-07-19T10:18:59Z</obo:IAO_0000232>
+        <rdfs:label>clinical history</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000016 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000016">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000123"/>
+        <obo:IAO_0000115 xml:lang="en">A representation of clinically significant bodily components, dispositions, and/or bodily processes of a human being that is inferred from relevant clinical findings.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2010-07-19T10:20:20Z</obo:IAO_0000232>
+        <rdfs:label>clinical picture</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000017 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000017">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000014"/>
+        <obo:IAO_0000115 xml:lang="en">A representation of an image that supports an inference to an assertion about some quality of a patient.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T10:21:10Z</obo:IAO_0000232>
+        <rdfs:label>image finding</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000018 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000018">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000014"/>
+        <obo:IAO_0000115 xml:lang="en">A representation of a quality of a specimen that is the output of a laboratory test and that can support an inference to an assertion about some quality of the patient.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T10:21:58Z</obo:IAO_0000232>
+        <rdfs:label>laboratory finding</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000019 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000019">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
+        <obo:IAO_0000115 xml:lang="en">A representation of a quality of a patient that is (1) recorded by a clinician because the quality is hypothesized to be of clinical significance and (2) refers to qualities obtaining in the patient prior to their becoming detectable in a clinical history taking or physical examination.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T10:22:44Z</obo:IAO_0000232>
+        <rdfs:label>preclinical finding</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000020 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000020">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
+        <obo:IAO_0000115 xml:lang="en">A process experienced by the patient, which can only be experienced by the patient, that is hypothesized to be clinically relevant.</obo:IAO_0000115>
+        <obo:IAO_0000116>note: defined class</obo:IAO_0000116>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2010-11-18T11:02:10Z
+Updated: 2020-07-06</obo:IAO_0000232>
+        <rdfs:label>symptom</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000022 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000022">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
+        <obo:IAO_0000115 xml:lang="en">A quality of a patient that is (a) a deviation from clinical normality that exists in virtue of the realization of a disease and (b) is observable.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:12:33Z</obo:IAO_0000232>
+        <rdfs:label>manifestation of a disease</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000023 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000023">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
+        <obo:IAO_0000115 xml:lang="en">A (combination of) quality(ies) of an organism determined by the interaction of its genetic make-up and environment that differentiates specific instances of a species from other instances of the same species.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2010-07-19T11:13:49Z</obo:IAO_0000232>
+        <rdfs:label>phenotype</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000024 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000024">
+        <rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
+        <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">The class sign has been replaced by three seperate classes which reflect the different types of signs possible.</rdfs:comment>
+        <rdfs:label>obsolete_sign</rdfs:label>
+        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000025 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000025">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000022"/>
+        <obo:IAO_0000115 xml:lang="en">A manifestation of a disease that is detectable in a clinical history taking or physical examination.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:15:43Z</obo:IAO_0000232>
+        <rdfs:label>clinical manifestation of a disease</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000026 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000026">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000022"/>
+        <obo:IAO_0000115 xml:lang="en">A manifestation of a disease that exists prior to the time at which it would be detected in a clinical history taking or physical examination, if the patient were to present to a clinician. A realization of a disease that exists prior to its becoming detectable in a clinical history taking or physical examination.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:16:50Z</obo:IAO_0000232>
+        <rdfs:label>preclinical manifestation of a disease</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000027 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000027">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000023"/>
+        <obo:IAO_0000115 xml:lang="en">A clinically abnormal phenotype.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:18:05Z</obo:IAO_0000232>
+        <rdfs:label>clinical phenotype</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000028 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000028">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000023"/>
+        <obo:IAO_0000115 xml:lang="en">A clinically abnormal phenotype that is characteristic of a single disease.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:18:39Z</obo:IAO_0000232>
+        <rdfs:label>disease phenotype</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000029 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000029">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000129"/>
+        <obo:IAO_0000115 xml:lang="en">A physical sign in which a non-zero value is standardly considered to be an indication that the organism is alive.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:19:17Z</obo:IAO_0000232>
+        <rdfs:label>vital sign</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000030 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000030">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
+        <obo:IAO_0000115 xml:lang="en">A disposition in an organism that constitutes an increased risk of the organism&apos;s subsequently developing the disease X.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:20:25Z</obo:IAO_0000232>
+        <rdfs:label>predisposition to disease of type X</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000031 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000031">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
+        <obo:IAO_0000115 xml:lang="en">A disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:21:20Z</obo:IAO_0000232>
+        <rdfs:label>disease</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000032 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000032">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:22:01Z</obo:IAO_0000232>
+        <rdfs:label>homeostasis</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000033 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000033">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000030"/>
+        <obo:IAO_0000115 xml:lang="en">A predisposition to disease of type X whose physical basis is a constitutional abnormality in an organism&apos;s genome. This abnormality is the physical basis for the increased risk of acquiring the disease X.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:23:07Z</obo:IAO_0000232>
+        <rdfs:label>genetic predisposition to disease of type X</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000034 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000034">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000031"/>
+        <obo:IAO_0000115 xml:lang="en">A disease whose physical basis is an acquired genetic disorder.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:24:05Z</obo:IAO_0000232>
+        <rdfs:label>acquired genetic disease</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000035 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000035">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000031"/>
+        <obo:IAO_0000115 xml:lang="en">A disease whose physical basis is a constitutional genetic disorder.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:24:59Z</obo:IAO_0000232>
+        <rdfs:label>constitutional genetic disease</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000037 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000037">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000032"/>
+        <obo:IAO_0000115 xml:lang="en">Homeostasis that is clinically abnormal for an organism of a given type and age in a given environment.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:26:44Z</obo:IAO_0000232>
+        <rdfs:label>abnormal homeostasis</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000038 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000038">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000032"/>
+        <obo:IAO_0000115 xml:lang="en">Homeostasis of a type that is not clinically abnormal.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:27:28Z</obo:IAO_0000232>
+        <rdfs:label>normal homeostasis</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000039 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000039">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
+        <obo:IAO_0000115 xml:lang="en">A quality which is an spatial arrangement or distribution of a(n) independent continuant(s) across a Three Dimensional Region.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:36:24Z</obo:IAO_0000232>
+        <rdfs:label>configuration</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000040 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000040">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000039"/>
+        <obo:IAO_0000115 xml:lang="en">A configuration which deviates in some way from a canonical configuration for a particular organism.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:36:58Z</obo:IAO_0000232>
+        <rdfs:label>pathological physical configuration</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000045 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000045">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
+        <obo:IAO_0000115 xml:lang="en">A material entity which is clinically abnormal and part of an extended organism. Disorders are the physical basis of disease.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:39:44Z</obo:IAO_0000232>
+        <rdfs:label>disorder</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000046 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000046">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000045"/>
+        <obo:IAO_0000115 xml:lang="en">A disorder whose etiology involves (1) a modification to the patient&apos;s genomic DNA which leads to alterations in the normal expression pattern of the genome, but is (2) not a change in the nucleotide sequence.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:40:27Z</obo:IAO_0000232>
+        <rdfs:label>epigenetic disorder</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000047 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000047">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000045"/>
+        <obo:IAO_0000115 xml:lang="en">A disorder whose etiology involves an abnormality in the nucleotide sequence of an organism&apos;s genome.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:41:14Z</obo:IAO_0000232>
+        <rdfs:label>genetic disorder</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000050 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000050">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000047"/>
+        <obo:IAO_0000115 xml:lang="en">A genetic disorder acquired by a single cell in an organism that leads to a population of cells within the organism bearing the disorder.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:43:09Z</obo:IAO_0000232>
+        <rdfs:label>acquired genetic disorder</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000051 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000051">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000047"/>
+        <obo:IAO_0000115 xml:lang="en">A genetic disorder inherited during conception that is part of all cells in the organism.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:43:44Z</obo:IAO_0000232>
+        <rdfs:label>constitutional genetic disorder</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000055 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000055">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000108"/>
+        <obo:IAO_0000115 xml:lang="en">A health care process in which a clinician elicits a description of previous sign and symptoms of disease from a patient or from a third party who is reporting on behalf of the patient.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:49:16Z</obo:IAO_0000232>
+        <rdfs:label>clinical history taking</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000056 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000056">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000108"/>
+        <obo:IAO_0000115 xml:lang="en">A measurement assay that has as input a patient-derived specimen and as output a data item that is about a quality of the specimen.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:49:49Z</obo:IAO_0000232>
+        <rdfs:label>clinical laboratory test</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000057 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000057">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000108"/>
+        <obo:IAO_0000115 xml:lang="en">A sequence of acts of observing and measuring qualities of a patient performed by a clinician; measurements may occur with and without elicitation.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2010-07-19T11:50:18Z</obo:IAO_0000232>
+        <rdfs:label>physical examination</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000059 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000059">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
+        <obo:IAO_0000115 xml:lang="en">A process in an organism that leads to a subsequent disorder.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:53:07Z</obo:IAO_0000232>
+        <rdfs:label>etiological process</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000060 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000060">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:53:49Z</obo:IAO_0000232>
+        <rdfs:label>bodily process</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000061 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000061">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000060"/>
+        <obo:IAO_0000115 xml:lang="en">A bodily process that is clinically abnormal.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:54:29Z</obo:IAO_0000232>
+        <rdfs:label>pathological bodily process</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000063 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000063">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
+        <obo:IAO_0000115 xml:lang="en">The totality of all processes through which a given disease instance is realized.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:55:44Z</obo:IAO_0000232>
+        <rdfs:label>disease course</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000064 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000064">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000063"/>
+        <obo:IAO_0000115 xml:lang="en">A disease course that (a) does not terminate in a return to normal homeostasis and (b) would, absent intervention, fall within abnormal homeostatic range.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:56:26Z
+
+10212020
+
+for definition use: 
+http://purl.obolibrary.org/obo/PATO_0001863</obo:IAO_0000232>
+        <rdfs:label>chronic disease course</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000065 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000065">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000063"/>
+        <obo:IAO_0000115 xml:lang="en">A disease course that (a) does not terminate in a return to normal homeostasis and (b) would, absent intervention, involve an increasing deviation from homeostasis.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:57:09Z</obo:IAO_0000232>
+        <rdfs:label>progressive disease course</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000066 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000066">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000063"/>
+        <obo:IAO_0000115 xml:lang="en">A disease course that terminates in a return to normal homeostasis.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:57:44Z</obo:IAO_0000232>
+        <rdfs:label>transient disease course</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000067 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000067">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000001"/>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:58:22Z</obo:IAO_0000232>
+        <rdfs:label>_undefined primitive term</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000069 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000069">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000067"/>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000232>creation date: 2009-06-23T11:59:24Z</obo:IAO_0000232>
+        <rdfs:label>clinically abnormal</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000070 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000070">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000067"/>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000232>creation date: 2009-06-23T12:00:09Z</obo:IAO_0000232>
+        <rdfs:label>physical basis</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000071 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000071">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000067"/>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000232>creation date: 2009-06-23T12:00:39Z</obo:IAO_0000232>
+        <rdfs:label>realization</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000073 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000073">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000123"/>
+        <obo:IAO_0000115 xml:lang="en">The representation of a conclusion of a diagnostic process.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-23T12:42:23Z</obo:IAO_0000232>
+        <rdfs:label>diagnosis</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000074 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000074">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
+        <obo:IAO_0000115 xml:lang="en">A value for a quality reported in a lab report and asserted by the testing lab or the kit manufacturer to be normal based on a statistical treatment of values from a reference population.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-06-26T10:31:34Z</obo:IAO_0000232>
+        <rdfs:label>normal value</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000077 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000077">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
+        <obo:IAO_0000115 xml:lang="en">TODO: Define, relate to disorder, and place in the OGMS hierarchy.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/bio/ISMB/ISMB_Bio-ontologies.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-07-13T02:14:59Z</obo:IAO_0000232>
+        <rdfs:label>pathological formation</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000078 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000078">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
+        <obo:IAO_0000115 xml:lang="en">An anatomical structure (FMA) is pathological whenever (1) it has come into being as a result of changes in some pre-existing canonical anatomical structure, (2) through processes other than the expression of the normal complement of genes of an organism of the given type, and (3) is predisposed to have health-related consequences for the organism in question manifested by symptoms and signs.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/bio/ISMB/ISMB_Bio-ontologies.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-07-13T02:14:05Z</obo:IAO_0000232>
+        <rdfs:label>pathological anatomical structure</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000079 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000079">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
+        <obo:IAO_0000115 xml:lang="en">TODO: Define, relate to disorder, and place in the OGMS hierarchy.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/bio/ISMB/ISMB_Bio-ontologies.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-07-13T02:15:17Z</obo:IAO_0000232>
+        <rdfs:label>portion of pathological body substance</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000080 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000080">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000061"/>
+        <obo:IAO_0000115 xml:lang="en">A pathological bodily process in which a canonical anatomical structure becomes a pathological anatomical structure.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/bio/ISMB/ISMB_Bio-ontologies.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-07-13T02:17:07Z</obo:IAO_0000232>
+        <rdfs:label>pathological transformation</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000081 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000081">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000061"/>
+        <obo:IAO_0000115 xml:lang="en">A pathological bodily process in which matter is reorganized in such a way as to give rise to new pathological formations which take the place of entities existing earlier.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/bio/ISMB/ISMB_Bio-ontologies.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-07-13T02:17:24Z</obo:IAO_0000232>
+        <rdfs:label>pathological derivation</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000082 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000082">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000061"/>
+        <obo:IAO_0000115 xml:lang="en">TODO: Define.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://ontology.buffalo.edu/bio/ISMB/ISMB_Bio-ontologies.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-07-13T02:17:47Z</obo:IAO_0000232>
+        <rdfs:label>pathological invasion</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000083 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000083">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000014"/>
+        <obo:IAO_0000115 xml:lang="en">TODO: Define.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://code.google.com/p/ogms/issues/detail?id=26</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-11-24T04:51:11Z</obo:IAO_0000232>
+        <rdfs:label>physical examination finding</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000084 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000084">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
+        <obo:IAO_0000115 xml:lang="en">An aggregate of organisms of the same type.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://code.google.com/p/ogms/issues/detail?id=33</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-11-24T04:51:11Z</obo:IAO_0000232>
+        <rdfs:label>organism population</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000085 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000085">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000020"/>
+        <obo:IAO_0000115 xml:lang="en">A bodily process in an organism S involving two integrated levels: (a) activation of the nociceptive system and associated emotion generating brain components of S, and (b) a simultaneous aversive sensory and emotional experience on the part of S, where (b) is phenomenologically similar to the sort of aversive experience involved in pain with concordant tissue damage.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://www.referent-tracking.com/RTU/sendfile/?file=painTokyo1_27_2011.pdf</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-11-24T04:51:11Z</obo:IAO_0000232>
+        <rdfs:label>pain</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000086 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000086">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
+        <obo:IAO_0000115 xml:lang="en">A pattern of signs and symptoms that typically co-occur.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://code.google.com/p/ogms/issues/detail?id=32</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2009-11-24T04:51:11Z</obo:IAO_0000232>
+        <rdfs:label>syndrome</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000087 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000087">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
+        <obo:IAO_0000115 xml:lang="en">An object aggregate consisting of an organism and all material entities located within the organism, overlapping the organism, or occupying sites formed in part by the organism.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://code.google.com/p/ogms/issues/detail?id=3</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2010-01-25T04:51:11Z</obo:IAO_0000232>
+        <rdfs:label>extended organism</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000088 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000088">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
+        <obo:IAO_0000115 xml:lang="en">A communication from a patient about something they perceive as being abnormal about their body or life.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://code.google.com/p/ogms/issues/detail?id=12</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2010-01-25T04:51:11Z</obo:IAO_0000232>
+        <rdfs:label>patient symptom report</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000089 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000089">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
+        <obo:IAO_0000115 xml:lang="en">A structurally anomalous part of an organism acquired during fetal development and present at birth (but not necessarily hereditary) which is hypothesized to be harmful for the organism.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000118>congenital malformation</obo:IAO_0000118>
+        <obo:IAO_0000119>http://code.google.com/p/ogms/issues/detail?id=28</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2010-03-31T04:51:11Z</obo:IAO_0000232>
+        <rdfs:label>congenital disorder</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000090 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000090">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000096"/>
+        <obo:IAO_0000115 xml:lang="en">A planned process whose completion is hypothesized by a health care provider to eliminate, prevent, or alleviate a disorder, the signs and symptoms of a disorder, or a pathological process</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://code.google.com/p/ogms/issues/detail?id=35</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2010-03-31T04:51:11Z</obo:IAO_0000232>
+        <rdfs:label>treatment</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000091 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000091">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
+        <obo:IAO_0000115 xml:lang="en">A processual entity during which a patient participating in a disease course gradually returns to participating in a canonical life course.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://code.google.com/p/ogms/issues/detail?id=35</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2010-03-31T04:51:11Z</obo:IAO_0000232>
+        <rdfs:label>convalescence</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000092 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000092">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
+        <obo:IAO_0000115 xml:lang="en">A process which has as parts all the processes in which a given organism is participant.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain
+Richard Scheuermann
+Sagar Jain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://code.google.com/p/ogms/issues/detail?id=38</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2010-03-31T04:51:11Z
+
+EDIT: 10 NOV 2015</obo:IAO_0000232>
+        <rdfs:label>life course</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000093 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000093">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
+        <obo:IAO_0000115 xml:lang="en">A hypothesis about some future part of a disease course.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://code.google.com/p/ogms/issues/detail?id=35</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2010-03-31T12:42:23Z</obo:IAO_0000232>
+        <rdfs:label>prognosis</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000094 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000094">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000063"/>
+        <obo:IAO_0000115 xml:lang="en">A disease course with an acute onset</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://code.google.com/p/ogms/wiki/Meeting_notes_20100513</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2010-07-19T11:57:44Z
+
+10212020
+
+for definition use
+
+http://purl.obolibrary.org/obo/PATO_0000389</obo:IAO_0000232>
+        <rdfs:label>acute disease course</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000095 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000095">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000060"/>
+        <obo:IAO_0000115 xml:lang="en">A bodily process caused by some disorder that results in recruitment of leukocytes into a localized tissue site, typically causing localized pain and swelling.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain
+Richard Scheuermann
+Sagar Jain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://code.google.com/p/ogms/wiki/Meeting_notes_20100513</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2010-07-19T11:57:44Z
+
+Updated: 10 NOV 2015</obo:IAO_0000232>
+        <rdfs:label>inflammatory process</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000096 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000096">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
+        <obo:IAO_0000115 xml:lang="en">A planned process with the objective to improve the health status of a patient that directly involves the treatment, diagnosis, or prevention of disease or injury of a patient</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain
+Sagar Jain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://groups.google.com/group/ogms-discuss/browse_thread/thread/a2dbc2ed1dff99d6</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2011-02-21T09:57:44Z
+editor date: 2017-04-18</obo:IAO_0000232>
+        <rdfs:label>health care process</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000097 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000097">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000096"/>
+        <obo:IAO_0000115 xml:lang="en">A temporally-connected health care process that has as participants an organization or person realizing the health care provider role and a person realizing the patient role.  The health care provider role and patient are realized during the health care encounter</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://groups.google.com/group/ogms-discuss/browse_thread/thread/a2dbc2ed1dff99d6</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2011-02-21T09:57:44Z</obo:IAO_0000232>
+        <rdfs:label>health care encounter</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000098 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000098">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000096"/>
+        <obo:IAO_0000115 xml:lang="en">TODO</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://groups.google.com/group/ogms-discuss/browse_thread/thread/a2dbc2ed1dff99d6</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2011-02-21T09:57:44Z</obo:IAO_0000232>
+        <rdfs:comment>09/16/2020
+Is this same as admission? 
+Is this the same as inpatient encounter?</rdfs:comment>
+        <rdfs:label>hospitalization</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000099 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000099">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000097"/>
+        <obo:IAO_0000115 xml:lang="en">TODO</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://groups.google.com/group/ogms-discuss/browse_thread/thread/a2dbc2ed1dff99d6</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2011-02-21T09:57:44Z</obo:IAO_0000232>
+        <rdfs:label>outpatient encounter</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000100 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000100">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000097"/>
+        <obo:IAO_0000115 xml:lang="en">A health care encounter involving a patient who has been admitted to a health care facility and remains in a hospital facility for at least one night.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://groups.google.com/group/ogms-discuss/browse_thread/thread/a2dbc2ed1dff99d6</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2011-02-21T09:57:44Z</obo:IAO_0000232>
+        <rdfs:label>inpatient encounter</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000101 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000101">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000097"/>
+        <obo:IAO_0000115 xml:lang="en">A health care encounter in which care is provided for undifferentiated and unscheduled patients with illnesses or injuries requiring immediate medical attention.</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://groups.google.com/group/ogms-discuss/browse_thread/thread/a2dbc2ed1dff99d6</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2011-02-21T09:57:44Z</obo:IAO_0000232>
+        <rdfs:label>emergency department encounter</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000102 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000102">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000045"/>
+        <obo:IAO_0000115 xml:lang="en">A disorder that involves some structural damage that is immediately caused by a catastrophic external force.</obo:IAO_0000115>
+        <obo:IAO_0000116>At the scale of organism (as opposed to the cellular scale or the population scale), an injury is typically the result of a catastrophic event. Consider the implications of making &apos;injury&apos; a subtype of &apos;disorder&apos;.
+
+Note: Adopted subtype of disorder, and injury can occur at the scale of organism down to cellular level.</obo:IAO_0000116>
+        <obo:IAO_0000117>Albert Goldfain
+Sagar Jain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://groups.google.com/group/ogms-discuss/browse_thread/thread/ca0ad373f27774c5
+
+OGMS call adoption- 16 SEPT 2015
+https://docs.google.com/document/d/1iiV1-fTS7BUUSzDw3N_Afx42698YWf54-FOTY2NkAxo/edit</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2011-09-20T09:57:44Z
+edited date: 30 SEPT 2015</obo:IAO_0000232>
+        <rdfs:label>injury</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000103 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000103">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
+        <obo:IAO_0000115 xml:lang="en">A planned process whose completion is hypothesized by a health care provider to reduce the risk of developing a disorder or the signs and symptoms of a disorder.</obo:IAO_0000115>
+        <obo:IAO_0000116>Whether or not &apos;prophylaxis&apos; and &apos;treatment&apos; classes are disjoint is an open question.</obo:IAO_0000116>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://groups.google.com/group/ogms-discuss/browse_thread/thread/e42bde79218ee34e</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2011-09-20T09:57:44Z</obo:IAO_0000232>
+        <rdfs:label>disease prophylaxis</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000104 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000104">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000096"/>
+        <obo:IAO_0000115 xml:lang="en">A health care process that involves the interpretation of a clinical picture from a given patient (input) and the assertion to the effect that the patient has a disease, disorder, or syndrome of a certain type, or none of these (output).</obo:IAO_0000115>
+        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://groups.google.com/group/ogms-discuss/browse_thread/thread/2a7008f311fac766/e7de486c94dfd82e</obo:IAO_0000119>
+        <obo:IAO_0000232>creation date: 2011-09-20T09:57:44Z</obo:IAO_0000232>
+        <rdfs:label>diagnostic process</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000105 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000105">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000278"/>
+        <obo:IAO_0000115>A disease stage which is preceded by a remission and characterized by the return of a manifestation of a disease.</obo:IAO_0000115>
+        <obo:IAO_0000116 xml:lang="en">A pathological bodily process which is part of a disease couse that occurs after an incomplete remission and that is similar to earlier parts of the disease course.</obo:IAO_0000116>
+        <obo:IAO_0000117>Albert Goldfain
+Richard Scheuermann
+Sagar Jain</obo:IAO_0000117>
+        <obo:IAO_0000118>recurrent</obo:IAO_0000118>
+        <obo:IAO_0000119>http://code.google.com/p/ogms/issues/detail?id=73</obo:IAO_0000119>
+        <dc:date>10 NOV 2015</dc:date>
+        <rdfs:label xml:lang="en">relapse</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000106 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000106">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000278"/>
+        <obo:IAO_0000115>A disease stage which is characterized by the lack of a manifestation of a disease</obo:IAO_0000115>
+        <obo:IAO_0000116 xml:lang="en">A part of a disease course in which the extent or rate of change of the signs and symptoms of a disorder has decreased.</obo:IAO_0000116>
+        <obo:IAO_0000117>Albert Goldfain
+Richard Scheuermann
+Sagar Jain</obo:IAO_0000117>
+        <obo:IAO_0000119>http://code.google.com/p/ogms/issues/detail?id=73</obo:IAO_0000119>
+        <dc:date>10 NOV 2015</dc:date>
+        <rdfs:label xml:lang="en">remission</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000107 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000107">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
+        <obo:IAO_0000115>A planned process that has the objective to support the objective of a health care process without directly involving the treatment, diagnosis, or prevention of disease or injury of a patient.</obo:IAO_0000115>
+        <dc:date>2017-04-18</dc:date>
+        <dc:publisher>Sagar Jain</dc:publisher>
+        <rdfs:label>ancillary health care process</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000108 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000108">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000096"/>
+        <obo:IAO_0000115>A health care process with the objective to produce information about the material entity that is the evaluant, by physically examining it or its proxies.</obo:IAO_0000115>
+        <dc:date>creation: 16MAY2017</dc:date>
+        <dc:publisher>Sagar Jain</dc:publisher>
+        <rdfs:label>health care process assay</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000109 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000109">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000096"/>
+        <obo:IAO_0000115>A health care process which results in physical changes in a specified input material</obo:IAO_0000115>
+        <dc:date>creation: 16MAY2017</dc:date>
+        <dc:publisher>Sagar Jain</dc:publisher>
+        <rdfs:label>health care process biomaterial transformation</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000110 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000110">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000096"/>
+        <obo:IAO_0000115>A health care process that produces output from input data</obo:IAO_0000115>
+        <dc:date>creation: 16MAY2017</dc:date>
+        <dc:publisher>Sagar Jain</dc:publisher>
+        <rdfs:label>health care process data transformation</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000111 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000111">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000090"/>
+        <obo:IAO_0000115>A treatment whose completion is hypothesized by a health care provider to prevent the signs and symptoms of a disorder or pathological process.</obo:IAO_0000115>
+        <obo:IAO_0000232>Creation date: 2018-11-27</obo:IAO_0000232>
+        <rdfs:label xml:lang="en">prophylactic treatment</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000112 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000112">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000090"/>
+        <obo:IAO_0000115>A treatment whose completion is hypothesized by a health care provider to eliminate a disorder or to alleviate the signs and symptoms of a disorder or pathological process.</obo:IAO_0000115>
+        <obo:IAO_0000232>Creation data: 2018-11-27</obo:IAO_0000232>
+        <rdfs:label xml:lang="en">therapeutic procedure</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000113 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000113">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000112"/>
+        <obo:IAO_0000115>A therapeutic procedure that uses synthetic or naturally-occurring chemicals</obo:IAO_0000115>
+        <obo:IAO_0000232>creation date: 2018-11-27</obo:IAO_0000232>
+        <rdfs:label xml:lang="en">chemotherapy procedure</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000114 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000114">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000112"/>
+        <obo:IAO_0000115>A therapeutic procedure that uses immune system derived entities.</obo:IAO_0000115>
+        <obo:IAO_0000232>creation date: 2018-11-27</obo:IAO_0000232>
+        <rdfs:label xml:lang="en">immunotherapy procedure</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000115 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000115">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000112"/>
+        <obo:IAO_0000115>A therapeutic procedure that uses physical conditioning</obo:IAO_0000115>
+        <obo:IAO_0000232>creation date: 2018-11-27</obo:IAO_0000232>
+        <rdfs:label xml:lang="en">physical therapy procedure</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000116 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000116">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000112"/>
+        <obo:IAO_0000115>A therapeutic procedure that uses radiation.</obo:IAO_0000115>
+        <obo:IAO_0000232>creation date: 2018-11-27</obo:IAO_0000232>
+        <rdfs:label xml:lang="en">radiation therapy procedure</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000117 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000117">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000278"/>
+        <obo:IAO_0000115>A disease stage characterized by the lack of symptoms associated with a given disease</obo:IAO_0000115>
+        <obo:IAO_0000232>creation date: 2018-11-27</obo:IAO_0000232>
+        <rdfs:label xml:lang="en">asymptomatic</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000118 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000118">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000278"/>
+        <obo:IAO_0000115>A disease stage that marks the beginning of a disease</obo:IAO_0000115>
+        <obo:IAO_0000232>creation date 2018-11-27</obo:IAO_0000232>
+        <rdfs:label xml:lang="en">onset</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000119 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000119">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000118"/>
+        <obo:IAO_0000115>A disease stage with a rapid unfolding of signs and symptoms</obo:IAO_0000115>
+        <obo:IAO_0000232>creation date 2018-11-27</obo:IAO_0000232>
+        <rdfs:label xml:lang="en">acute onset</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000120 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000120">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000106"/>
+        <obo:IAO_0000115>A remission which is characterized by a prolonged lack of all manifestations of a disease</obo:IAO_0000115>
+        <rdfs:label xml:lang="en">complete remission</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000121 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000121">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000106"/>
+        <obo:IAO_0000115>A remission which is characterized by a prolonged lack of some manifestations of a disease</obo:IAO_0000115>
+        <rdfs:label xml:lang="en">partial remission</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000122 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000122">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
+        <obo:IAO_0000115>A quality in which complete clearance of the disorder is attained; however, physiological &apos;memory&apos; may persist</obo:IAO_0000115>
+        <obo:IAO_0000232>creation date: 2018-11-27</obo:IAO_0000232>
+        <rdfs:label xml:lang="en">recovered from disease</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000123 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000123">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
+        <obo:IAO_0000115>A data item that is about a patient and is the specified output of a health care process assay or diagnostic process</obo:IAO_0000115>
+        <obo:IAO_0000232>creation date: 2018-11-27</obo:IAO_0000232>
+        <rdfs:label xml:lang="en">clinical data item</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000124 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000124">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000099"/>
+        <obo:IAO_0000115>A health care encounter that is regularly scheduled for the purpose of health monitoring.</obo:IAO_0000115>
+        <obo:IAO_0000118>routine clinical visit</obo:IAO_0000118>
+        <rdfs:label>routine health care encounter</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000125 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000125">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000099"/>
+        <obo:IAO_0000115>A health care encounter that is scheduled for the purpose of assessing a known set of specific issues</obo:IAO_0000115>
+        <obo:IAO_0000118>follow-up clinical visit</obo:IAO_0000118>
+        <rdfs:label>follow-up health care encounter</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000126 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000126">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000089"/>
+        <obo:IAO_0000115>A congenital disorder arising as a result of an infectious process</obo:IAO_0000115>
+        <rdfs:label>congenital infection</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000127 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000127">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000089"/>
+        <obo:IAO_0000115>A congenital disorder arising as a result of a drug exposure causing an anatomical abnormality</obo:IAO_0000115>
+        <rdfs:label>drug induced congenital malformation</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000128 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000128">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000061"/>
+        <obo:IAO_0000115>A pathological bodily process that occurs in the fetus during fetal development</obo:IAO_0000115>
+        <rdfs:label>congenital process</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000129 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000129">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
+        <obo:IAO_0000115>An abnormal material entity that is part of a patient and hypothesized to be clinically relevant.</obo:IAO_0000115>
+        <obo:IAO_0000232>Example: an abnormal growth, an inflammatory infiltrate, swollen tissue, distension</obo:IAO_0000232>
+        <rdfs:label>physical sign</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000130 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000130">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000061"/>
+        <obo:IAO_0000115>The process in which an allergic disease unfolds.</obo:IAO_0000115>
+        <rdfs:label>allergic disease process</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000131 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000131">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000061"/>
+        <obo:IAO_0000115>The process in which cancer unfolds</obo:IAO_0000115>
+        <rdfs:label>cancer process</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000132 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000132">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000061"/>
+        <obo:IAO_0000115>The process in which an autoimmune disease unfolds.</obo:IAO_0000115>
+        <rdfs:label>autoimmune disease process</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000133 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000133">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000278"/>
+        <rdfs:label>progression stage</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000134 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000134">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000133"/>
+        <rdfs:label>cancer progression stage</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000135 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000135">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000134"/>
+        <obo:IAO_0000115>A cancer progression stage characterized by abnormal cellular growth contained within normal tissue boundaries (e.g. carcinoma in situ).</obo:IAO_0000115>
+        <rdfs:label>cancer progression stage 0</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000136 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000136">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000134"/>
+        <obo:IAO_0000115>A cancer progression stage characterized by abnormal cellular growth that extends through normal local tissue boundaries as a contiguous mass.</obo:IAO_0000115>
+        <rdfs:label>cancer progression stage I</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000137 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000137">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000134"/>
+        <obo:IAO_0000115>A cancer progression stage characterized by abnormal cellular growth that extends well beyond normal local tissue boundaries as a contiguous mass.</obo:IAO_0000115>
+        <rdfs:label>cancer progression stage II</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000138 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000138">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000134"/>
+        <obo:IAO_0000115>A cancer progression stage characterized by abnormal cellular growth that extends through normal local tissue boundaries as a contiguous mass and includes metastasis to one or more regional draining lymph nodes.</obo:IAO_0000115>
+        <rdfs:label>cancer progression stage III</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000139 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000139">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000134"/>
+        <obo:IAO_0000115>A cancer progression stage characterized by abnormal cellular growth that extends through normal local tissue boundaries as a contiguous mass and includes metastasis to other distant tissues besides lymph nodes.</obo:IAO_0000115>
+        <rdfs:label>cancer progression stage IV</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000140 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000140">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000061"/>
+        <obo:IAO_0000115>The process in which an infectious disease unfolds</obo:IAO_0000115>
+        <rdfs:label>infectious disease process</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000141 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000141">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
+        <obo:IAO_0000115>An abnormal processual entity occuring in a patient that is hypothesized to be clinically relevant.</obo:IAO_0000115>
+        <rdfs:label>processual sign</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000142 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000142">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
+        <obo:IAO_0000115>An abnormal observable quality of a part of a patient that is hypothesized to be clinically relevant.</obo:IAO_0000115>
+        <obo:IAO_0000232>Example: the color of a rash; the shape of a melanoma</obo:IAO_0000232>
+        <rdfs:label>qualitative sign</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000143 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000143">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000112"/>
+        <obo:IAO_0000115>A therapeutic procedure in which a body part is transferred into a organism</obo:IAO_0000115>
+        <rdfs:label>transplantation</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000144 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000144">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000143"/>
+        <obo:IAO_0000115>A transplantation in which the body part is a non-fluid tissue</obo:IAO_0000115>
+        <rdfs:label>solid organ transplant</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000145 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000145">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000143"/>
+        <obo:IAO_0000115>A transplantation in which the body part is a bodily fluid</obo:IAO_0000115>
+        <rdfs:label>transfusion</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000146 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000146">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000045"/>
+        <obo:IAO_0000115>A disorder of some macroscopic part of a tissue</obo:IAO_0000115>
+        <rdfs:label>tissue disorder</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000147 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000147">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000146"/>
+        <obo:IAO_0000115>A tissue disorder that has resulted from a dysregulation of cell proliferation leading to a net increase in mass</obo:IAO_0000115>
+        <rdfs:label>neoplasm</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/OGMS_0000148 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000148">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
+        <obo:IAO_0000115>A role borne by some material entity which can be delivered/administrated into some organism and the role is realized during a clinical treatment process aiming to treat symptoms, signs or diagnosed disease.</obo:IAO_0000115>
+        <obo:IAO_0000116>Originally OBIB_0000026</obo:IAO_0000116>
+        <rdfs:label>medication role</rdfs:label>
+    </owl:Class>
+    
+
+
+    <!-- 
+    ///////////////////////////////////////////////////////////////////////////////////////
+    //
+    // Individuals
+    //
+    ///////////////////////////////////////////////////////////////////////////////////////
+     -->
+
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000002 -->
+
+    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000002">
+        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
+        <obo:IAO_0000111 xml:lang="en">example to be eventually removed</obo:IAO_0000111>
+        <rdfs:label xml:lang="en">example to be eventually removed</rdfs:label>
+    </owl:NamedIndividual>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000103 -->
+
+    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000103">
+        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000225"/>
+        <obo:IAO_0000111 xml:lang="en">failed exploratory term</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">The term was used in an attempt to structure part of the ontology but in retrospect failed to do a good job</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
+        <rdfs:label xml:lang="en">failed exploratory term</rdfs:label>
+    </owl:NamedIndividual>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000120 -->
+
+    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000120">
+        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
+        <obo:IAO_0000111 xml:lang="en">metadata complete</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete.</obo:IAO_0000115>
+        <rdfs:label xml:lang="en">metadata complete</rdfs:label>
+    </owl:NamedIndividual>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000121 -->
+
+    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000121">
+        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
+        <obo:IAO_0000111 xml:lang="en">organizational term</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">Term created to ease viewing/sort terms for development purpose, and will not be included in a release</obo:IAO_0000115>
+        <rdfs:label xml:lang="en">organizational term</rdfs:label>
+    </owl:NamedIndividual>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000122 -->
+
+    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000122">
+        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
+        <obo:IAO_0000111 xml:lang="en">ready for release</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking &quot;ready_for_release&quot; should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release.  Those classes deemed &quot;ready_for_release&quot; will also derived from a chain of ancestor classes that are also &quot;ready_for_release.&quot;</obo:IAO_0000115>
+        <rdfs:label xml:lang="en">ready for release</rdfs:label>
+    </owl:NamedIndividual>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000123 -->
+
+    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000123">
+        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
+        <obo:IAO_0000111 xml:lang="en">metadata incomplete</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors.</obo:IAO_0000115>
+        <rdfs:label xml:lang="en">metadata incomplete</rdfs:label>
+    </owl:NamedIndividual>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000124 -->
+
+    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000124">
+        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
+        <obo:IAO_0000111 xml:lang="en">uncurated</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">Nothing done yet beyond assigning a unique class ID and proposing a preferred term.</obo:IAO_0000115>
+        <rdfs:label xml:lang="en">uncurated</rdfs:label>
+    </owl:NamedIndividual>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000125 -->
+
+    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000125">
+        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
+        <obo:IAO_0000111 xml:lang="en">pending final vetting</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor.</obo:IAO_0000115>
+        <rdfs:label xml:lang="en">pending final vetting</rdfs:label>
+    </owl:NamedIndividual>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000224 -->
+
+    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000224">
+        <obo:IAO_0000115 xml:lang="en">Core is an instance of a grouping of terms from an ontology or ontologies. It is used by the ontology to identify main classes.</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
+        <obo:IAO_0000117 xml:lang="en">PERSON: Melanie Courtot</obo:IAO_0000117>
+        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
+        <rdfs:label xml:lang="en">obsolete_core</rdfs:label>
+        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
+    </owl:NamedIndividual>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000226 -->
+
+    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000226">
+        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000225"/>
+        <obo:IAO_0000111 xml:lang="en">placeholder removed</obo:IAO_0000111>
+        <rdfs:label xml:lang="en">placeholder removed</rdfs:label>
+    </owl:NamedIndividual>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000227 -->
+
+    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000227">
+        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000225"/>
+        <obo:IAO_0000111 xml:lang="en">terms merged</obo:IAO_0000111>
+        <obo:IAO_0000116 xml:lang="en">An editor note should explain what were the merged terms and the reason for the merge.</obo:IAO_0000116>
+        <rdfs:label xml:lang="en">terms merged</rdfs:label>
+    </owl:NamedIndividual>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000228 -->
+
+    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000228">
+        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000225"/>
+        <obo:IAO_0000111 xml:lang="en">term imported</obo:IAO_0000111>
+        <obo:IAO_0000116 xml:lang="en">This is to be used when the original term has been replaced by a term imported from an other ontology. An editor note should indicate what is the URI of the new term to use.</obo:IAO_0000116>
+        <rdfs:label xml:lang="en">term imported</rdfs:label>
+    </owl:NamedIndividual>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000229 -->
+
+    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000229">
+        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000225"/>
+        <obo:IAO_0000111 xml:lang="en">term split</obo:IAO_0000111>
+        <obo:IAO_0000116 xml:lang="en">This is to be used when a term has been split in two or more new terms. An editor note should indicate the reason for the split and indicate the URIs of the new terms created.</obo:IAO_0000116>
+        <rdfs:label xml:lang="en">term split</rdfs:label>
+    </owl:NamedIndividual>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000410 -->
+
+    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000410">
+        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000409"/>
+        <obo:IAO_0000111 xml:lang="en">universal</obo:IAO_0000111>
+        <obo:IAO_0000116 xml:lang="en">Hard to give a definition for. Intuitively a &quot;natural kind&quot; rather than a collection of any old things, which a class is able to be, formally. At the meta level, universals are defined as positives, are disjoint with their siblings, have single asserted parents.</obo:IAO_0000116>
+        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">A Formal Theory of Substances, Qualities, and Universals, http://ontology.buffalo.edu/bfo/SQU.pdf</obo:IAO_0000119>
+        <rdfs:label xml:lang="en">universal</rdfs:label>
+    </owl:NamedIndividual>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000420 -->
+
+    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000420">
+        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000409"/>
+        <obo:IAO_0000111 xml:lang="en">defined class</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal</obo:IAO_0000115>
+        <obo:IAO_0000116 xml:lang="en">&quot;definitions&quot;, in some readings, always are given by necessary and sufficient conditions. So one must be careful (and this is difficult sometimes) to distinguish between defined classes and universal.</obo:IAO_0000116>
+        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
+        <rdfs:label xml:lang="en">defined class</rdfs:label>
+    </owl:NamedIndividual>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000421 -->
+
+    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000421">
+        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000409"/>
+        <obo:IAO_0000111 xml:lang="en">named class expression</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">A named class expression is a logical expression that is given a name. The name can be used in place of the expression.</obo:IAO_0000115>
+        <obo:IAO_0000116 xml:lang="en">named class expressions are used in order to have more concise logical definition but their extensions may not be interesting classes on their own. In languages such as OWL, with no provisions for macros, these show up as actuall classes. Tools may with to not show them as such, and to replace uses of the macros with their expansions</obo:IAO_0000116>
+        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
+        <rdfs:label xml:lang="en">named class expression</rdfs:label>
+    </owl:NamedIndividual>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000423 -->
+
+    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000423">
+        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
+        <obo:IAO_0000111 xml:lang="en">to be replaced with external ontology term</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">Terms with this status should eventually replaced with a term from another ontology.</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">group:OBI</obo:IAO_0000119>
+        <rdfs:label xml:lang="en">to be replaced with external ontology term</rdfs:label>
+    </owl:NamedIndividual>
+    
+
+
+    <!-- http://purl.obolibrary.org/obo/IAO_0000428 -->
+
+    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000428">
+        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
+        <obo:IAO_0000111 xml:lang="en">requires discussion</obo:IAO_0000111>
+        <obo:IAO_0000115 xml:lang="en">A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues.</obo:IAO_0000115>
+        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
+        <obo:IAO_0000119 xml:lang="en">group:OBI</obo:IAO_0000119>
+        <rdfs:label xml:lang="en">requires discussion</rdfs:label>
+    </owl:NamedIndividual>
+    
+
+
+    <!-- 
+    ///////////////////////////////////////////////////////////////////////////////////////
+    //
+    // General axioms
+    //
+    ///////////////////////////////////////////////////////////////////////////////////////
+     -->
+
+    <rdf:Description>
+        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#AllDifferent"/>
+        <owl:distinctMembers rdf:parseType="Collection">
+            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000120"/>
+            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000121"/>
+            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000122"/>
+            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000123"/>
+            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000124"/>
+            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000125"/>
+            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000423"/>
+            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000428"/>
+        </owl:distinctMembers>
+    </rdf:Description>
+    <rdf:Description>
+        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#AllDifferent"/>
+        <owl:distinctMembers rdf:parseType="Collection">
+            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000226"/>
+            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000227"/>
+            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000228"/>
+            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000229"/>
+        </owl:distinctMembers>
+    </rdf:Description>
+</rdf:RDF>
+
+
+
+<!-- Generated by the OWL API (version 4.5.6) https://github.com/owlcs/owlapi -->
+