@sjcrh/proteinpaint-server 2.145.1-0 → 2.145.1
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/dataset/termdb.test.js +0 -1
- package/package.json +3 -3
- package/routes/termdb.cluster.js +28 -93
- package/src/app.js +32 -98
package/dataset/termdb.test.js
CHANGED
package/package.json
CHANGED
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@@ -1,6 +1,6 @@
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{
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"name": "@sjcrh/proteinpaint-server",
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-
"version": "2.145.1
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"version": "2.145.1",
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"type": "module",
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"description": "a genomics visualization tool for exploring a cohort's genotype and phenotype data",
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"main": "src/app.js",
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@@ -63,9 +63,9 @@
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"@sjcrh/augen": "2.143.0",
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"@sjcrh/proteinpaint-python": "2.144.0",
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"@sjcrh/proteinpaint-r": "2.145.1-0",
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"@sjcrh/proteinpaint-rust": "2.145.1
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"@sjcrh/proteinpaint-rust": "2.145.1",
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"@sjcrh/proteinpaint-shared": "2.145.1-0",
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"@sjcrh/proteinpaint-types": "2.145.1-
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"@sjcrh/proteinpaint-types": "2.145.1-1",
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"@types/express": "^5.0.0",
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"@types/express-session": "^1.18.1",
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"better-sqlite3": "^9.4.1",
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package/routes/termdb.cluster.js
CHANGED
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@@ -213,22 +213,6 @@ async function validate_query_geneExpression(ds, genome) {
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}
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throw "unknown queries.geneExpression.src";
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}
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async function queryGeneExpression(hdf5_file, geneNames) {
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const jsonInput = JSON.stringify({
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hdf5_file,
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gene: geneNames
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});
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try {
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const result = await run_rust("readHDF5", jsonInput);
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if (!result || result.length === 0) {
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throw new Error("Failed to retrieve expression data: Empty or missing response");
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}
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return result;
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} catch (error) {
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console.error(`Error querying gene expression for ${geneNames}`);
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throw error;
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}
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}
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async function queryHDF5(hdf5_file, query) {
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const jsonInput = JSON.stringify({
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hdf5_file,
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@@ -250,34 +234,16 @@ async function validateNative(q, ds) {
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q.samples = [];
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try {
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await utils.file_is_readable(q.file);
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if (q.newformat) {
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tmp = await run_rust("readH5", JSON.stringify({ hdf5_file: q.file, validate: true }));
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} else {
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tmp = await run_rust("validateHDF5", JSON.stringify({ hdf5_file: q.file }));
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}
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const tmp = await run_rust("readH5", JSON.stringify({ hdf5_file: q.file, validate: true }));
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const vr = JSON.parse(tmp);
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if (vr.status !== "success") throw vr.message;
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if (
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q.samples.push(si);
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}
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console.log(`${ds.label}: geneExpression HDF5 file validated. Format: ${vr.format}, Samples:`, vr.samples.length);
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} else {
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if (!vr.sampleNames?.length) throw "HDF5 file has no samples, please check file.";
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for (const sn of vr.sampleNames) {
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const si = ds.cohort.termdb.q.sampleName2id(sn);
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if (si == void 0) throw `unknown sample ${sn} from HDF5 ${q.file}`;
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q.samples.push(si);
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}
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console.log(
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`${ds.label}: geneExpression HDF5 file validated. Format: ${vr.format}, Samples:`,
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vr.sampleNames.length
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);
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if (!vr.samples?.length) throw "HDF5 file has no samples, please check file.";
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for (const sn of vr.samples) {
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const si = ds.cohort.termdb.q.sampleName2id(sn);
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if (si == void 0) throw `unknown sample ${sn} from HDF5 ${q.file}`;
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q.samples.push(si);
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}
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console.log(`${ds.label}: geneExpression HDF5 file validated. Format: ${vr.format}, Samples:`, vr.samples.length);
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} catch (error) {
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throw `${ds.label}: Failed to validate geneExpression HDF5 file: ${error}`;
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}
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@@ -310,63 +276,32 @@ async function validateNative(q, ds) {
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return { term2sample2value, byTermId };
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}
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const time1 = Date.now();
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if (q.newformat) {
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geneData = JSON.parse(await queryHDF5(q.file, geneNames));
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} else {
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geneData = JSON.parse(await queryGeneExpression(q.file, geneNames));
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}
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const geneData = JSON.parse(await queryHDF5(q.file, geneNames));
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mayLog("Time taken to run gene query:", formatElapsedTime(Date.now() - time1));
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continue;
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}
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const samplesData = geneResult.samples || {};
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const s2v = {};
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for (const sampleName in samplesData) {
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const sampleId = ds.cohort.termdb.q.sampleName2id(sampleName);
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if (!sampleId) continue;
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if (limitSamples && !limitSamples.has(sampleId)) continue;
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s2v[sampleId] = samplesData[sampleName];
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}
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if (Object.keys(s2v).length) {
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term2sample2value.set(tw.$id, s2v);
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}
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const genesData = geneData.query_output || {};
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if (!genesData) throw "No expression data returned from HDF5 query";
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for (const tw of param.terms) {
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if (!tw.term.gene) continue;
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const geneResult = genesData[tw.term.gene];
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if (!geneResult) {
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console.warn(`No data found for gene ${tw.term.gene} in the response`);
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continue;
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}
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const samplesData = geneResult.samples || {};
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const s2v = {};
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for (const sampleName in samplesData) {
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const sampleId = ds.cohort.termdb.q.sampleName2id(sampleName);
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if (!sampleId) continue;
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if (limitSamples && !limitSamples.has(sampleId)) continue;
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s2v[sampleId] = samplesData[sampleName];
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}
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for (const tw of param.terms) {
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if (!tw.term.gene) continue;
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const geneResult = genesData[tw.term.gene];
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if (!geneResult) {
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console.warn(`No data found for gene ${tw.term.gene} in the response`);
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continue;
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}
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const samplesData = geneResult.samples || {};
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const s2v = {};
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for (const [sampleName, value] of Object.entries(samplesData)) {
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const sampleId = ds.cohort.termdb.q.sampleName2id(sampleName);
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if (!sampleId) continue;
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if (limitSamples && !limitSamples.has(sampleId)) continue;
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s2v[sampleId] = value;
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}
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if (Object.keys(s2v).length) {
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term2sample2value.set(tw.$id, s2v);
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}
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}
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if (term2sample2value.size == 0) {
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throw "No data available for the input " + param.terms?.map((tw) => tw.term.gene).join(", ");
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if (Object.keys(s2v).length) {
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term2sample2value.set(tw.$id, s2v);
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}
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}
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if (term2sample2value.size == 0) {
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throw "No data available for the input " + param.terms?.map((tw) => tw.term.gene).join(", ");
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}
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return { term2sample2value, byTermId, bySampleId };
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};
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}
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