@sjcrh/proteinpaint-client 2.224.2 → 2.225.0
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/dist/2dmaf-4W2R2HXG.js +1362 -0
- package/dist/AggMatrixInput-3SQ7UW5L.js +402 -0
- package/dist/AggregateMatrix-QI55DXDU.js +37 -0
- package/dist/AppHeader-C26OHIUQ.js +826 -0
- package/dist/BoxPlot-27OYBGJ3.js +1247 -0
- package/dist/CorrelationVolcano-XIMXCSHG.js +613 -0
- package/dist/Cuminc-737O733E.js +1217 -0
- package/dist/DE-EDTGDY6L.js +85 -0
- package/dist/DEinput-ZN76I5M5.js +479 -0
- package/dist/DM-25IRANGL.js +86 -0
- package/dist/DifferentialAnalysis-7HQYEA5T.js +236 -0
- package/dist/Disco-4YNXWGRX.js +3445 -0
- package/dist/Disco-4YNXWGRX.js.map +7 -0
- package/dist/Disco.UI-67HBGS4Y.js +239 -0
- package/dist/DmrPlot-KZVDVPUT.js +366 -0
- package/dist/DmrPlot-KZVDVPUT.js.map +7 -0
- package/dist/GB-HT3B7Y7R.js +1388 -0
- package/dist/GSEA-CMFMNK5Y.js +870 -0
- package/dist/GeneExpInput-HMGV23E7.js +38 -0
- package/dist/Geomap-RB4SGVPC.js +80 -0
- package/dist/HicApp-YRP6YQFA.js +2240 -0
- package/dist/IDCViewer-OUSOZNSR.js +10810 -0
- package/dist/NumBinaryEditor-YFQDPBB6.js +274 -0
- package/dist/NumBinaryEditor.unit.spec-6YC5PCPK.js +308 -0
- package/dist/NumContEditor-EH6MA2RW.js +100 -0
- package/dist/NumContEditor.unit.spec-Q2JBVIRT.js +160 -0
- package/dist/NumCustomBinEditor-USQA3BC6.js +29 -0
- package/dist/NumCustomBinEditor.unit.spec-PE2HFRCK.js +393 -0
- package/dist/NumDiscreteEditor-VKE4WT24.js +165 -0
- package/dist/NumDiscreteEditor.unit.spec-JNG673LE.js +229 -0
- package/dist/NumRegularBinEditor-KCCPGJSX.js +29 -0
- package/dist/NumRegularBinEditor.unit.spec-4BLKQRZU.js +274 -0
- package/dist/NumSplineEditor-4YELHGUO.js +205 -0
- package/dist/NumSplineEditor.unit.spec-CKHHK6GH.js +220 -0
- package/dist/NumericDensity-LCFM7VSY.js +29 -0
- package/dist/NumericDensity.unit.spec-R4ARTJ5I.js +414 -0
- package/dist/NumericHandler-2OHRSY6Z.js +30 -0
- package/dist/NumericHandler.unit.spec-M3TRIFZW.js +225 -0
- package/dist/ProteomeInput-G2EP6QH2.js +610 -0
- package/dist/Regression-2HKE6C7F.js +1412 -0
- package/dist/RunChart2-WRVW63PB.js +744 -0
- package/dist/SC-37RDNFGH.js +1290 -0
- package/dist/Violin-KD6FPWC7.js +1105 -0
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- package/dist/Volcano-U62TCDEL.js +2748 -0
- package/dist/Volcano-U62TCDEL.js.map +7 -0
- package/dist/Wsi-PB77PVAA.js +637 -0
- package/dist/aboutSunburst-5Z24ODIN.js +93 -0
- package/dist/adSandbox-AFORHU3V.js +29 -0
- package/dist/animatedBubbleChart-F75OBRZW.js +542 -0
- package/dist/app-4RZ76DZZ.js +28 -0
- package/dist/app-IHE3RNI5.js +38 -0
- package/dist/app.js +14 -14
- package/dist/bam-IIRZX3IK.js +872 -0
- package/dist/barchart-UIHRIMOE.js +38 -0
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- package/dist/block-COZKGPXY.js +6203 -0
- package/dist/block.init-UBXYVTPQ.js +29 -0
- package/dist/block.mds.expressionrank-KSXPPPGR.js +350 -0
- package/dist/block.mds.geneboxplot-5RDFDVDE.js +819 -0
- package/dist/block.mds.junction-LMM24KXJ.js +1534 -0
- package/dist/block.mds.svcnv-4XRXZMPS.js +6325 -0
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- package/dist/block.tk.aicheck-6GHZK2YY.js +274 -0
- package/dist/block.tk.bam-7H3BSHR2.js +1906 -0
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- package/dist/block.tk.ld-RFQPDG7Q.js +90 -0
- package/dist/block.tk.menu-JDJU2OGK.js +1050 -0
- package/dist/block.tk.pgv-G2UFCQUT.js +934 -0
- package/dist/brainImaging-ASAHWZJH.js +550 -0
- package/dist/brainRegions-XTJDLUU4.js +213 -0
- package/dist/bubbleHeatmap-UPUITTU6.js +374 -0
- package/dist/cellTypeBubbleHeatmap-25SOXC2Q.js +274 -0
- package/dist/chunk-2N345NXD.js +5790 -0
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- package/dist/cohort-ZFGFEEBD.js +66 -0
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- package/dist/databrowser.ui-YNKDTAAN.js +424 -0
- package/dist/dictionary-OTR6Z5EZ.js +109 -0
- package/dist/dnaMethylation-LQTCTOOE.js +29 -0
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- package/dist/expclust.gdc.spec-CYGWGREQ.js +298 -0
- package/dist/facet-IZSSZDHK.js +556 -0
- package/dist/gb-AUZBUZFM.js +77 -0
- package/dist/geneExpClustering-AQBFLXLP.js +240 -0
- package/dist/geneExpression-HDJVPVPK.js +309 -0
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- package/dist/hierCluster-7IOPNYFN.js +55 -0
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- /package/dist/{scatter-KMAZ3ZNR.js.map → scatter-YQ47446T.js.map} +0 -0
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import "./chunk-PWYMHUXY.js";
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40
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import "./chunk-TLT4YIG3.js";
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41
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import "./chunk-5R63Q5KH.js";
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42
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import {
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43
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select_default
|
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44
|
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} from "./chunk-I6Y4O3RR.js";
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45
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import "./chunk-Q5RDQNIT.js";
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46
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import "./chunk-HS5PO5ZQ.js";
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47
|
-
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48
|
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// plots/animatedBubbleChart.ts
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49
|
-
var defaultConfig = { chartType: "animatedBubbleChart" };
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50
|
-
var SPLIT_W = 1100;
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51
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var SPLIT_H = 900;
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52
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var MIN_R = 6;
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53
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var MAX_R = 43;
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54
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var INNER_CIRCLE_RATIO = 0.75;
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55
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var RING_GAP = 1;
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56
|
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var PADDING = 0;
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57
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var HOVER_SCALE = 1.2;
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58
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var HOVER_COLLIDE_BOOST = 1.4;
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59
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var HOVER_REPEL_REACH = 91;
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var HOVER_REPEL_STRENGTH = 0.17;
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61
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var GRAVITY_STRENGTH = 0.28;
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62
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var HOVER_GRAVITY = 0.045;
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63
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var AnimatedBubbleChart = class _AnimatedBubbleChart extends PlotBase {
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64
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constructor(opts, api) {
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65
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super(opts, api);
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66
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this.simulation = null;
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67
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this.selectedRankingKey = null;
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68
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this.groupBy = "all";
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69
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// State for the split-view toggle. Stored on the instance so the toggle handler
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70
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// can recompute layout + restart the simulation without re-fetching data.
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71
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this.currentNodes = [];
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72
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this.currentAssays = [];
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73
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// 'all'-mode packed-cluster enclosing radius (+slack); set by computeHomes and used by
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74
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// the per-tick circular clamp, so we don't pack the same nodes twice.
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75
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this.allModeBoundaryR = 0;
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76
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this.modalityLabelsSel = null;
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77
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// Computed each time we enter split mode: where each modality's sub-cluster sits.
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78
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// Sizes vary because we hierarchically pack groups by their natural cluster radii.
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79
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// `topY` is the topmost EDGE of the cluster (min(homeY - outerR)) — bubble radii
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80
|
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// aren't scaled with the layout, so the visual extent reaches farther up than
|
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81
|
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// `cy - r*scale`. Labels use this so they always sit clear of every bubble.
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82
|
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this.groupCenters = [];
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83
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this.svgSel = null;
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84
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this.wrapperSel = null;
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85
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// Computed by `computeHomes` from the actual home positions + bubble radii.
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86
|
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// Drives the wrapper's visible width/height so the chart frame hugs the cluster
|
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87
|
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// instead of inheriting the much larger fixed SPLIT canvas size.
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88
|
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this.contentBbox = {
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89
|
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minX: 0,
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90
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minY: 0,
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91
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maxX: 0,
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92
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maxY: 0
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93
|
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};
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94
|
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this.BBOX_PAD = 20;
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95
|
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this.type = _AnimatedBubbleChart.type;
|
|
96
|
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this.components = {};
|
|
97
|
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}
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98
|
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static {
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99
|
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this.type = "animatedBubbleChart";
|
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100
|
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}
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101
|
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/** Internal SVG coordinate space — fixed, used by computeHomes for layout math. */
|
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102
|
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canvasW() {
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return SPLIT_W;
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|
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}
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|
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canvasH() {
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|
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return SPLIT_H;
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|
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}
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|
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/** Visible viewport — sized to the actual content bbox + padding, not a fixed constant. */
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|
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viewportW() {
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|
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return Math.max(50, this.contentBbox.maxX - this.contentBbox.minX + 2 * this.BBOX_PAD);
|
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111
|
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}
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112
|
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viewportH() {
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return Math.max(50, this.contentBbox.maxY - this.contentBbox.minY + 2 * this.BBOX_PAD);
|
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114
|
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}
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|
115
|
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async init() {
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|
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const holder = this.opts.holder.append("div").style("padding", "10px");
|
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|
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this.dom = {
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holder,
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|
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controls: holder.append("div").style("display", "flex").style("gap", "14px").style("align-items", "center").style("margin-bottom", "10px"),
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body: holder.append("div"),
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|
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tip: new Menu({ padding: "" }),
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122
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header: this.opts.header
|
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123
|
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};
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if (this.dom.header) this.dom.header.html("Bubble Chart");
|
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125
|
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}
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126
|
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getState(appState) {
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127
|
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const config = appState.plots.find((p) => p.id === this.id);
|
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128
|
-
if (!config) throw `No plot with id='${this.id}' found`;
|
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|
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return { config };
|
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130
|
-
}
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|
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async main() {
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|
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await this.fetchAndRender(this.selectedRankingKey ?? void 0);
|
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|
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}
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|
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async fetchAndRender(rankingKey) {
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|
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const body = {
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|
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genome: this.app.opts.state.vocab.genome,
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137
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dslabel: this.app.opts.state.vocab.dslabel
|
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|
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};
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|
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if (rankingKey) body.rankingKey = rankingKey;
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140
|
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const data = await dofetch3("termdb/animatedBubbleChart", { body });
|
|
141
|
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if (this.simulation) {
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142
|
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this.simulation.stop();
|
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143
|
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this.simulation = null;
|
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144
|
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}
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145
|
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if (data.error) {
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146
|
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if (data.rankingKeys?.length) this.renderControls(data.rankingKeys, rankingKey ?? data.rankingKeys[0]);
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147
|
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this.dom.body.selectAll("*").remove();
|
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|
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this.dom.body.append("div").style("padding", "20px").style("color", "#b00020").text(`Error: ${data.error}`);
|
|
149
|
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return;
|
|
150
|
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}
|
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151
|
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this.selectedRankingKey = data.selectedRankingKey;
|
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152
|
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this.renderControls(data.rankingKeys, data.selectedRankingKey);
|
|
153
|
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this.dom.body.selectAll("*").remove();
|
|
154
|
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if (!data.bubbles?.length) {
|
|
155
|
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this.dom.body.append("div").style("padding", "20px").style("color", "#666").text("No data in the selected ranking file.");
|
|
156
|
-
return;
|
|
157
|
-
}
|
|
158
|
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const container = this.dom.body.append("div").style("display", "flex").style("gap", "24px").style("align-items", "flex-start").style("flex-wrap", "nowrap");
|
|
159
|
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const colorScale = getColors(data.assays.length).domain(data.assays);
|
|
160
|
-
const assayColors = {};
|
|
161
|
-
for (const a of data.assays) assayColors[a] = colorScale(a);
|
|
162
|
-
this.renderBubbles(container, data.bubbles, assayColors);
|
|
163
|
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this.renderLegend(container, data.assays, assayColors);
|
|
164
|
-
}
|
|
165
|
-
renderControls(rankingKeys, current) {
|
|
166
|
-
this.dom.controls.selectAll("*").remove();
|
|
167
|
-
const sel = this.dom.controls.append("select").style("padding", "4px 8px").style("min-width", "200px");
|
|
168
|
-
sel.selectAll("option").data(rankingKeys).enter().append("option").attr("value", (d) => d).text((d) => d);
|
|
169
|
-
sel.property("value", current);
|
|
170
|
-
sel.on("change", () => this.fetchAndRender(sel.node().value));
|
|
171
|
-
const tabsHolder = this.dom.controls.append("div");
|
|
172
|
-
const tabsToggle = new Tabs({
|
|
173
|
-
holder: tabsHolder,
|
|
174
|
-
noContent: true,
|
|
175
|
-
tabs: [
|
|
176
|
-
{
|
|
177
|
-
label: "Combined",
|
|
178
|
-
active: this.groupBy === "all",
|
|
179
|
-
callback: () => {
|
|
180
|
-
if (this.groupBy === "all") return;
|
|
181
|
-
this.groupBy = "all";
|
|
182
|
-
this.applyGrouping();
|
|
183
|
-
}
|
|
184
|
-
},
|
|
185
|
-
{
|
|
186
|
-
label: "Split by dominant data type",
|
|
187
|
-
active: this.groupBy === "modality",
|
|
188
|
-
callback: () => {
|
|
189
|
-
if (this.groupBy === "modality") return;
|
|
190
|
-
this.groupBy = "modality";
|
|
191
|
-
this.applyGrouping();
|
|
192
|
-
}
|
|
193
|
-
}
|
|
194
|
-
]
|
|
195
|
-
});
|
|
196
|
-
tabsToggle.main();
|
|
197
|
-
}
|
|
198
|
-
/** Find the modality (assay) that contributes the largest slice to this gene's wheel. */
|
|
199
|
-
dominantAssay(node) {
|
|
200
|
-
let bestAssay = node.slices[0]?.assay ?? this.currentAssays[0];
|
|
201
|
-
let bestAngle = -1;
|
|
202
|
-
for (const s of node.slices) {
|
|
203
|
-
if (s.angle > bestAngle) {
|
|
204
|
-
bestAngle = s.angle;
|
|
205
|
-
bestAssay = s.assay;
|
|
206
|
-
}
|
|
207
|
-
}
|
|
208
|
-
return bestAssay;
|
|
209
|
-
}
|
|
210
|
-
/** Compute homeX/homeY on every node based on the current `groupBy` mode. */
|
|
211
|
-
computeHomes() {
|
|
212
|
-
const nodes = this.currentNodes;
|
|
213
|
-
if (!nodes.length) return;
|
|
214
|
-
const W = this.canvasW();
|
|
215
|
-
const H = this.canvasH();
|
|
216
|
-
if (this.groupBy === "all") {
|
|
217
|
-
const packInputs = nodes.map((n) => ({ r: n.outerR, x: 0, y: 0 }));
|
|
218
|
-
siblings_default(packInputs);
|
|
219
|
-
const enclose = enclose_default(packInputs) ?? { x: 0, y: 0, r: Math.min(W, H) / 2 };
|
|
220
|
-
const dx2 = W / 2 - enclose.x;
|
|
221
|
-
const dy2 = H / 2 - enclose.y;
|
|
222
|
-
for (let i = 0; i < nodes.length; i++) {
|
|
223
|
-
nodes[i].homeX = packInputs[i].x + dx2;
|
|
224
|
-
nodes[i].homeY = packInputs[i].y + dy2;
|
|
225
|
-
}
|
|
226
|
-
this.allModeBoundaryR = enclose.r + 2;
|
|
227
|
-
this.groupCenters = [];
|
|
228
|
-
this.recordContentBbox();
|
|
229
|
-
return;
|
|
230
|
-
}
|
|
231
|
-
const assays = this.currentAssays;
|
|
232
|
-
const LABEL_GAP = 200;
|
|
233
|
-
const buckets = /* @__PURE__ */ new Map();
|
|
234
|
-
for (const a of assays) buckets.set(a, []);
|
|
235
|
-
for (const n of nodes) buckets.get(this.dominantAssay(n))?.push(n);
|
|
236
|
-
const layouts = [];
|
|
237
|
-
for (const assay of assays) {
|
|
238
|
-
const groupNodes = buckets.get(assay) ?? [];
|
|
239
|
-
if (!groupNodes.length) continue;
|
|
240
|
-
const packs = groupNodes.map((n) => ({ r: n.outerR, x: 0, y: 0 }));
|
|
241
|
-
siblings_default(packs);
|
|
242
|
-
const enclose = enclose_default(packs) ?? { x: 0, y: 0, r: 0 };
|
|
243
|
-
let naturalExtent = 0;
|
|
244
|
-
for (let j = 0; j < groupNodes.length; j++) {
|
|
245
|
-
const dx2 = packs[j].x - enclose.x;
|
|
246
|
-
const dy2 = packs[j].y - enclose.y;
|
|
247
|
-
const reach = Math.sqrt(dx2 * dx2 + dy2 * dy2) + groupNodes[j].outerR;
|
|
248
|
-
if (reach > naturalExtent) naturalExtent = reach;
|
|
249
|
-
}
|
|
250
|
-
layouts.push({ assay, nodes: groupNodes, packs, enclose, naturalExtent });
|
|
251
|
-
}
|
|
252
|
-
const superCircles = layouts.map((g) => ({ r: g.naturalExtent + LABEL_GAP, x: 0, y: 0 }));
|
|
253
|
-
siblings_default(superCircles);
|
|
254
|
-
const overallEnclose = enclose_default(superCircles) ?? { x: 0, y: 0, r: 1 };
|
|
255
|
-
const margin = 10;
|
|
256
|
-
const maxR = Math.min(W, H) / 2 - margin;
|
|
257
|
-
const scale = overallEnclose.r > maxR ? maxR / overallEnclose.r : 1;
|
|
258
|
-
const dx = W / 2 - overallEnclose.x * scale;
|
|
259
|
-
const dy = H / 2 - overallEnclose.y * scale;
|
|
260
|
-
this.groupCenters = [];
|
|
261
|
-
for (let i = 0; i < layouts.length; i++) {
|
|
262
|
-
const g = layouts[i];
|
|
263
|
-
const groupCx = superCircles[i].x * scale + dx;
|
|
264
|
-
const groupCy = superCircles[i].y * scale + dy;
|
|
265
|
-
const offX = groupCx - g.enclose.x;
|
|
266
|
-
const offY = groupCy - g.enclose.y;
|
|
267
|
-
for (let j = 0; j < g.nodes.length; j++) {
|
|
268
|
-
g.nodes[j].homeX = g.packs[j].x + offX;
|
|
269
|
-
g.nodes[j].homeY = g.packs[j].y + offY;
|
|
270
|
-
}
|
|
271
|
-
this.groupCenters.push({
|
|
272
|
-
assay: g.assay,
|
|
273
|
-
cx: groupCx,
|
|
274
|
-
cy: groupCy,
|
|
275
|
-
r: g.naturalExtent,
|
|
276
|
-
topY: groupCy - g.naturalExtent
|
|
277
|
-
});
|
|
278
|
-
}
|
|
279
|
-
let minX = Infinity, minY = Infinity, maxX = -Infinity, maxY = -Infinity;
|
|
280
|
-
for (const n of nodes) {
|
|
281
|
-
if (n.homeX - n.outerR < minX) minX = n.homeX - n.outerR;
|
|
282
|
-
if (n.homeY - n.outerR < minY) minY = n.homeY - n.outerR;
|
|
283
|
-
if (n.homeX + n.outerR > maxX) maxX = n.homeX + n.outerR;
|
|
284
|
-
if (n.homeY + n.outerR > maxY) maxY = n.homeY + n.outerR;
|
|
285
|
-
}
|
|
286
|
-
if (Number.isFinite(minX)) {
|
|
287
|
-
const shiftX = W / 2 - (minX + maxX) / 2;
|
|
288
|
-
const shiftY = H / 2 - (minY + maxY) / 2;
|
|
289
|
-
for (const n of nodes) {
|
|
290
|
-
n.homeX += shiftX;
|
|
291
|
-
n.homeY += shiftY;
|
|
292
|
-
}
|
|
293
|
-
for (const g of this.groupCenters) {
|
|
294
|
-
g.cx += shiftX;
|
|
295
|
-
g.cy += shiftY;
|
|
296
|
-
g.topY += shiftY;
|
|
297
|
-
}
|
|
298
|
-
}
|
|
299
|
-
this.recordContentBbox();
|
|
300
|
-
}
|
|
301
|
-
/** Record the FINAL content bbox (after recentering) so the wrapper can hug the
|
|
302
|
-
* cluster instead of inheriting a fixed canvas size. Called by both modes. */
|
|
303
|
-
recordContentBbox() {
|
|
304
|
-
const nodes = this.currentNodes;
|
|
305
|
-
if (!nodes.length) return;
|
|
306
|
-
let bx0 = Infinity, by0 = Infinity, bx1 = -Infinity, by1 = -Infinity;
|
|
307
|
-
for (const n of nodes) {
|
|
308
|
-
if (n.homeX - n.outerR < bx0) bx0 = n.homeX - n.outerR;
|
|
309
|
-
if (n.homeY - n.outerR < by0) by0 = n.homeY - n.outerR;
|
|
310
|
-
if (n.homeX + n.outerR > bx1) bx1 = n.homeX + n.outerR;
|
|
311
|
-
if (n.homeY + n.outerR > by1) by1 = n.homeY + n.outerR;
|
|
312
|
-
}
|
|
313
|
-
if (this.groupBy === "modality") {
|
|
314
|
-
for (const g of this.groupCenters) {
|
|
315
|
-
const labelY = g.topY - 32;
|
|
316
|
-
if (labelY < by0) by0 = labelY;
|
|
317
|
-
}
|
|
318
|
-
}
|
|
319
|
-
if (Number.isFinite(bx0)) {
|
|
320
|
-
this.contentBbox = { minX: bx0, minY: by0, maxX: bx1, maxY: by1 };
|
|
321
|
-
}
|
|
322
|
-
}
|
|
323
|
-
/** Toggle handler — recompute homes for the current groupBy and reheat the simulation. */
|
|
324
|
-
applyGrouping() {
|
|
325
|
-
this.computeHomes();
|
|
326
|
-
if (this.wrapperSel) {
|
|
327
|
-
this.wrapperSel.transition().duration(900).style("width", `${this.viewportW()}px`).style("height", `${this.viewportH()}px`);
|
|
328
|
-
}
|
|
329
|
-
if (this.svgSel) {
|
|
330
|
-
this.svgSel.transition().duration(900).style("left", `${this.BBOX_PAD - this.contentBbox.minX}px`).style("top", `${this.BBOX_PAD - this.contentBbox.minY}px`);
|
|
331
|
-
}
|
|
332
|
-
const centerByAssay = new Map(this.groupCenters.map((g) => [g.assay, g]));
|
|
333
|
-
if (this.modalityLabelsSel) {
|
|
334
|
-
const labels = this.modalityLabelsSel.selectAll("text");
|
|
335
|
-
if (this.groupBy === "modality") {
|
|
336
|
-
labels.transition().duration(900).attr("opacity", (assay) => centerByAssay.has(assay) ? 1 : 0).attr("x", (assay) => centerByAssay.get(assay)?.cx ?? 0).attr("y", (assay) => {
|
|
337
|
-
const g = centerByAssay.get(assay);
|
|
338
|
-
return g ? g.cy - g.r - 12 : 0;
|
|
339
|
-
});
|
|
340
|
-
} else {
|
|
341
|
-
labels.transition().duration(400).attr("opacity", 0);
|
|
342
|
-
}
|
|
343
|
-
}
|
|
344
|
-
if (this.simulation) {
|
|
345
|
-
this.simulation.force("x", x_default((d) => d.homeX).strength(GRAVITY_STRENGTH)).force("y", y_default((d) => d.homeY).strength(GRAVITY_STRENGTH)).velocityDecay(0.55).alpha(0.6).alphaDecay(0.018).restart();
|
|
346
|
-
setTimeout(() => {
|
|
347
|
-
if (this.simulation) this.simulation.velocityDecay(0.4).alphaDecay(0.022);
|
|
348
|
-
}, 2500);
|
|
349
|
-
}
|
|
350
|
-
}
|
|
351
|
-
renderBubbles(container, bubbles, assayColors) {
|
|
352
|
-
const maxRank = Math.max(...bubbles.map((b) => b.integrativeRank));
|
|
353
|
-
const sizeScale = sqrt().domain([1, maxRank]).range([MAX_R, MIN_R]).clamp(true);
|
|
354
|
-
const nodes = bubbles.map((b) => {
|
|
355
|
-
const outerR = sizeScale(b.integrativeRank);
|
|
356
|
-
const innerR = outerR * INNER_CIRCLE_RATIO;
|
|
357
|
-
const slices = [];
|
|
358
|
-
let cum = 0;
|
|
359
|
-
for (const s of b.slices) {
|
|
360
|
-
const start = cum;
|
|
361
|
-
const end = cum + s.angle;
|
|
362
|
-
slices.push({ ...s, startAngle: start, endAngle: end });
|
|
363
|
-
cum = end;
|
|
364
|
-
}
|
|
365
|
-
return {
|
|
366
|
-
gene: b.gene,
|
|
367
|
-
integrativeRank: b.integrativeRank,
|
|
368
|
-
orderStatQ: b.orderStatQ,
|
|
369
|
-
pValue: b.pValue,
|
|
370
|
-
fdr: b.fdr,
|
|
371
|
-
slices,
|
|
372
|
-
innerR,
|
|
373
|
-
outerR,
|
|
374
|
-
// Seed positions in a small jitter around center so the simulation pulls them outward to home
|
|
375
|
-
x: this.canvasW() / 2 + (Math.random() - 0.5) * 80,
|
|
376
|
-
y: this.canvasH() / 2 + (Math.random() - 0.5) * 80,
|
|
377
|
-
homeX: 0,
|
|
378
|
-
// filled in by packSiblings below
|
|
379
|
-
homeY: 0,
|
|
380
|
-
hovered: false
|
|
381
|
-
};
|
|
382
|
-
});
|
|
383
|
-
this.currentNodes = nodes;
|
|
384
|
-
this.currentAssays = Object.keys(assayColors);
|
|
385
|
-
this.computeHomes();
|
|
386
|
-
const wrapper = container.append("div").style("position", "relative").style("overflow", "hidden").style("width", `${this.viewportW()}px`).style("height", `${this.viewportH()}px`);
|
|
387
|
-
this.wrapperSel = wrapper;
|
|
388
|
-
const svg = wrapper.append("svg").attr("width", this.canvasW()).attr("height", this.canvasH()).style("position", "absolute").style("left", `${this.BBOX_PAD - this.contentBbox.minX}px`).style("top", `${this.BBOX_PAD - this.contentBbox.minY}px`);
|
|
389
|
-
this.svgSel = svg;
|
|
390
|
-
const root = svg.append("g");
|
|
391
|
-
const arcGen = arc_default().startAngle((d) => d.startAngle).endAngle((d) => d.endAngle);
|
|
392
|
-
const groups = root.selectAll("g.sjpp-abc-bubble").data(nodes).enter().append("g").attr("class", "sjpp-abc-bubble").attr("transform", (d) => `translate(${d.x},${d.y})`).style("cursor", "pointer").attr("role", "button").attr("tabindex", 0).attr("aria-label", (d) => `Open protein view for ${d.gene}`);
|
|
393
|
-
groups.append("circle").attr("class", "hit-area").attr("r", (d) => d.outerR).attr("fill", "transparent");
|
|
394
|
-
groups.each(function(d) {
|
|
395
|
-
const slicesG = select_default(this).append("g").attr("class", "ring");
|
|
396
|
-
const visible = d.slices.filter((s) => s.angle > 0);
|
|
397
|
-
slicesG.selectAll("path").data(visible).enter().append("path").attr("fill", (s) => assayColors[s.assay] ?? "#999").attr("stroke", "#fff").attr("stroke-width", 0.8).attr("opacity", 0).attr(
|
|
398
|
-
"d",
|
|
399
|
-
(s) => arcGen({
|
|
400
|
-
...s,
|
|
401
|
-
innerRadius: d.innerR + RING_GAP,
|
|
402
|
-
outerRadius: d.outerR
|
|
403
|
-
})
|
|
404
|
-
);
|
|
405
|
-
});
|
|
406
|
-
groups.append("circle").attr("class", "inner").attr("r", 0).attr("fill", "#fff").attr("stroke", "#333").attr("stroke-width", 1);
|
|
407
|
-
const labelFontSize = (d) => {
|
|
408
|
-
const byRadius = d.innerR * 0.72;
|
|
409
|
-
const maxByWidth = d.innerR * 1.8 / Math.max(d.gene.length * 0.6, 1);
|
|
410
|
-
return Math.max(5, Math.min(byRadius, maxByWidth, 20));
|
|
411
|
-
};
|
|
412
|
-
groups.append("text").attr("text-anchor", "middle").attr("dominant-baseline", "central").attr("font-weight", "bold").attr("font-size", (d) => `${labelFontSize(d)}px`).attr("fill", "#222").attr("pointer-events", "none").attr("opacity", 0).text((d) => d.gene);
|
|
413
|
-
const tip = this.dom.tip;
|
|
414
|
-
groups.on("mouseenter", (event, d) => {
|
|
415
|
-
d.hovered = true;
|
|
416
|
-
if (this.simulation) {
|
|
417
|
-
this.simulation.force("x").strength(HOVER_GRAVITY);
|
|
418
|
-
this.simulation.force("y").strength(HOVER_GRAVITY);
|
|
419
|
-
this.simulation.alpha(0.5).restart();
|
|
420
|
-
}
|
|
421
|
-
tip.clear().show(event.clientX, event.clientY);
|
|
422
|
-
const t = tip.d.append("div").style("padding", "8px").style("font-size", "13px").style("min-width", "220px");
|
|
423
|
-
t.append("div").style("font-weight", "bold").style("font-size", "15px").style("margin-bottom", "4px").text(d.gene);
|
|
424
|
-
t.append("div").text(`Integrative rank: ${d.integrativeRank}`);
|
|
425
|
-
if (d.orderStatQ != null) t.append("div").text(`Order statistic Q: ${d.orderStatQ.toExponential(3)}`);
|
|
426
|
-
if (d.pValue != null)
|
|
427
|
-
t.append("div").text(`P value: ${d.pValue >= 1e-4 ? d.pValue.toFixed(4) : d.pValue.toExponential(3)}`);
|
|
428
|
-
if (d.fdr != null) t.append("div").text(`FDR: ${d.fdr >= 1e-4 ? d.fdr.toFixed(4) : d.fdr.toExponential(3)}`);
|
|
429
|
-
const table = t.append("table").style("margin-top", "6px").style("border-collapse", "collapse").style("font-size", "12px");
|
|
430
|
-
const header = table.append("tr");
|
|
431
|
-
header.append("th").style("text-align", "left").style("padding", "2px 6px").text("Data Type");
|
|
432
|
-
header.append("th").style("text-align", "right").style("padding", "2px 6px").text("Rank");
|
|
433
|
-
header.append("th").style("text-align", "right").style("padding", "2px 6px").text("Share");
|
|
434
|
-
for (const s of d.slices) {
|
|
435
|
-
const row = table.append("tr");
|
|
436
|
-
const swatch = row.append("td").style("padding", "2px 6px");
|
|
437
|
-
swatch.append("span").style("display", "inline-block").style("width", "10px").style("height", "10px").style("background", assayColors[s.assay] ?? "#999").style("margin-right", "6px").style("vertical-align", "middle");
|
|
438
|
-
swatch.append("span").text(s.assay);
|
|
439
|
-
row.append("td").style("padding", "2px 6px").style("text-align", "right").text(s.rank == null ? "NA" : String(s.rank));
|
|
440
|
-
row.append("td").style("padding", "2px 6px").style("text-align", "right").text(s.weight == null ? "\u2014" : `${(s.weight * 100).toFixed(1)}%`);
|
|
441
|
-
}
|
|
442
|
-
}).on("mouseleave", (_event, d) => {
|
|
443
|
-
d.hovered = false;
|
|
444
|
-
if (this.simulation) {
|
|
445
|
-
this.simulation.force("x").strength(GRAVITY_STRENGTH);
|
|
446
|
-
this.simulation.force("y").strength(GRAVITY_STRENGTH);
|
|
447
|
-
this.simulation.alpha(0.25).restart();
|
|
448
|
-
}
|
|
449
|
-
tip.hide();
|
|
450
|
-
}).on("click keydown", (event, d) => {
|
|
451
|
-
if (event.type === "keydown") {
|
|
452
|
-
const ke = event;
|
|
453
|
-
if (ke.key !== "Enter" && ke.key !== " ") return;
|
|
454
|
-
ke.preventDefault();
|
|
455
|
-
}
|
|
456
|
-
tip.hide();
|
|
457
|
-
this.app.dispatch({
|
|
458
|
-
type: "plot_create",
|
|
459
|
-
config: {
|
|
460
|
-
chartType: "proteinView",
|
|
461
|
-
tw: {
|
|
462
|
-
term: {
|
|
463
|
-
gene: d.gene,
|
|
464
|
-
name: d.gene,
|
|
465
|
-
type: TermTypes.PROTEOME_ABUNDANCE
|
|
466
|
-
}
|
|
467
|
-
}
|
|
468
|
-
}
|
|
469
|
-
});
|
|
470
|
-
});
|
|
471
|
-
groups.select("circle.inner").transition().duration(900).attr("r", (d) => d.innerR);
|
|
472
|
-
groups.select("g.ring").selectAll("path").transition().delay(200).duration(900).attr("opacity", 0.95);
|
|
473
|
-
groups.select("text").transition().delay(500).duration(600).attr("opacity", 1);
|
|
474
|
-
const assayNames = this.currentAssays;
|
|
475
|
-
const labelsG = svg.append("g").attr("class", "modality-labels");
|
|
476
|
-
labelsG.selectAll("text").data(assayNames).enter().append("text").attr("text-anchor", "middle").attr("dominant-baseline", "alphabetic").attr("font-size", "13px").attr("font-weight", "bold").attr("paint-order", "stroke").attr("stroke", "#fff").attr("stroke-width", 3).attr("stroke-linejoin", "round").attr("fill", (d) => assayColors[d] ?? "#333").attr("opacity", 0).attr("x", this.canvasW() / 2).attr("y", 12).text((d) => d);
|
|
477
|
-
this.modalityLabelsSel = labelsG;
|
|
478
|
-
if (this.groupBy === "modality") {
|
|
479
|
-
const centerByAssay = new Map(this.groupCenters.map((g) => [g.assay, g]));
|
|
480
|
-
labelsG.selectAll("text").attr("opacity", (assay) => centerByAssay.has(assay) ? 1 : 0).attr("x", (assay) => centerByAssay.get(assay)?.cx ?? this.canvasW() / 2).attr("y", (assay) => {
|
|
481
|
-
const g = centerByAssay.get(assay);
|
|
482
|
-
return g ? g.cy - g.r - 8 : 12;
|
|
483
|
-
});
|
|
484
|
-
}
|
|
485
|
-
const collideR = (d) => (d.hovered ? d.outerR * HOVER_COLLIDE_BOOST : d.outerR) + PADDING;
|
|
486
|
-
function hoverRepel(alpha) {
|
|
487
|
-
const h = nodes.find((n) => n.hovered);
|
|
488
|
-
if (!h) return;
|
|
489
|
-
const sizeRatio = h.outerR / MAX_R;
|
|
490
|
-
const reach = HOVER_REPEL_REACH * sizeRatio;
|
|
491
|
-
const strength = HOVER_REPEL_STRENGTH * sizeRatio;
|
|
492
|
-
if (reach < 1) return;
|
|
493
|
-
for (const n of nodes) {
|
|
494
|
-
if (n === h) continue;
|
|
495
|
-
const dx = n.x - h.x;
|
|
496
|
-
const dy = n.y - h.y;
|
|
497
|
-
const dist = Math.sqrt(dx * dx + dy * dy) || 0.01;
|
|
498
|
-
if (dist >= reach) continue;
|
|
499
|
-
const falloff = 1 - dist / reach;
|
|
500
|
-
const push = strength * falloff * alpha;
|
|
501
|
-
n.vx = (n.vx ?? 0) + dx / dist * push * reach;
|
|
502
|
-
n.vy = (n.vy ?? 0) + dy / dist * push * reach;
|
|
503
|
-
}
|
|
504
|
-
}
|
|
505
|
-
this.simulation = simulation_default(nodes).force("collide", collide_default(collideR).strength(1).iterations(2)).force("x", x_default((d) => d.homeX).strength(GRAVITY_STRENGTH)).force("y", y_default((d) => d.homeY).strength(GRAVITY_STRENGTH)).force("hoverRepel", hoverRepel).alpha(1).alphaDecay(0.022).alphaMin(1e-3).on("tick", () => {
|
|
506
|
-
if (this.groupBy === "all") {
|
|
507
|
-
const cxC = this.canvasW() / 2;
|
|
508
|
-
const cyC = this.canvasH() / 2;
|
|
509
|
-
for (const d of nodes) {
|
|
510
|
-
const ddx = d.x - cxC;
|
|
511
|
-
const ddy = d.y - cyC;
|
|
512
|
-
const dist = Math.sqrt(ddx * ddx + ddy * ddy) || 1e-4;
|
|
513
|
-
const maxDist = this.allModeBoundaryR - d.outerR;
|
|
514
|
-
if (dist > maxDist) {
|
|
515
|
-
d.x = cxC + ddx * maxDist / dist;
|
|
516
|
-
d.y = cyC + ddy * maxDist / dist;
|
|
517
|
-
}
|
|
518
|
-
}
|
|
519
|
-
}
|
|
520
|
-
groups.attr("transform", (d) => `translate(${d.x},${d.y})${d.hovered ? ` scale(${HOVER_SCALE})` : ""}`);
|
|
521
|
-
});
|
|
522
|
-
}
|
|
523
|
-
renderLegend(container, assays, assayColors) {
|
|
524
|
-
const legend = container.append("div").style("display", "flex").style("flex-direction", "column").style("gap", "6px").style("padding", "4px 0").style("min-width", "160px");
|
|
525
|
-
legend.append("div").style("font-weight", "bold").style("font-size", "13px").style("margin-bottom", "4px").text("Data Type");
|
|
526
|
-
for (const assay of assays) {
|
|
527
|
-
const row = legend.append("div").style("display", "flex").style("align-items", "center").style("gap", "8px").style("font-size", "12px");
|
|
528
|
-
row.append("span").style("display", "inline-block").style("width", "14px").style("height", "14px").style("background", assayColors[assay] ?? "#999").style("border", "1px solid #ccc");
|
|
529
|
-
row.append("span").text(assay);
|
|
530
|
-
}
|
|
531
|
-
}
|
|
532
|
-
};
|
|
533
|
-
var componentInit = getCompInit(AnimatedBubbleChart);
|
|
534
|
-
async function getPlotConfig(opts) {
|
|
535
|
-
const config = structuredClone(defaultConfig);
|
|
536
|
-
return copyMerge(config, opts);
|
|
537
|
-
}
|
|
538
|
-
export {
|
|
539
|
-
componentInit,
|
|
540
|
-
getPlotConfig
|
|
541
|
-
};
|
|
542
|
-
//# sourceMappingURL=animatedBubbleChart-HKOGYPSS.js.map
|