@sjcrh/proteinpaint-client 2.207.0 → 2.207.1

package/dist/chunk-2XOBD4ZZ.js

@@ -1,102 +0,0 @@
-import {
-  addGeneSearchbox,
-  first_genetrack_tolist,
-  getDNAMethUnit,
-  sayerror
-} from "./chunk-NQDF3U2C.js";
-import {
-  Menu
-} from "./chunk-ELJX3QIQ.js";
-import {
-  DNA_METHYLATION
-} from "./chunk-IZUYLFOX.js";
-
-// termdb/handlers/dnaMethylation.ts
-var SearchHandler = class {
-  init(opts) {
-    this.opts = opts;
-    this.callback = opts.callback;
-    this.app = opts.app;
-    const holder = opts.holder.append("div").style("margin", "10px 0px");
-    this.dom = {};
-    this.dom.errDiv = holder.append("div").style("margin", "5px 0px").style("display", "none");
-    this.dom.geneSearchDiv = holder.append("div");
-    this.dom.blockDiv = holder.append("div").style("display", "none").style("margin", "15px 4px");
-    const geneSearch = addGeneSearchbox({
-      tip: new Menu({ padding: "0px" }),
-      genome: opts.genomeObj,
-      row: this.dom.geneSearchDiv,
-      callback: async () => {
-        try {
-          this.dom.errDiv.style("display", "none");
-          await this.handleGeneSearch(geneSearch);
-        } catch (e) {
-          this.dom.errDiv.style("display", "block");
-          sayerror(this.dom.errDiv, "Error: " + (e.message || e));
-          if (e.stack) console.log(e.stack);
-        }
-      }
-    });
-  }
-  async handleGeneSearch(geneSearch) {
-    if (geneSearch.geneSymbol) {
-      const { chr, start, stop } = geneSearch;
-      if (!chr || !Number.isInteger(start) || !Number.isInteger(stop))
-        throw new Error("unable to retrieve gene coordinate");
-      this.dom.blockDiv.selectAll("*").remove();
-      this.dom.blockDiv.style("display", "block");
-      this.dom.blockDiv.append("div").style("opacity", 0.6).text("Navigate genome browser to desired region");
-      const arg = {
-        holder: this.dom.blockDiv,
-        genome: this.opts.genomeObj,
-        // genome obj
-        chr,
-        start,
-        stop,
-        tklst: [],
-        nobox: true,
-        width: 500,
-        hidegenelegend: true,
-        debugmode: this.opts.debug
-      };
-      first_genetrack_tolist(this.opts.genomeObj, arg.tklst);
-      const _ = await import("./block-A3I2INBA.js");
-      this.blockInstance = new _.Block(arg);
-      this.dom.submitBtn = this.dom.blockDiv.append("div").attr("data-testid", "sjpp-dnaMethylation-submitDiv").style("margin", "10px 0px").append("button").style("border", "none").style("border-radius", "20px").style("padding", "10px 15px").text("Submit Region").on("click", async () => {
-        const { chr: chr2, start: start2, stop: stop2 } = this.blockInstance.rglst[0];
-        const term = this.makeTerm({ chr: chr2, start: start2, stop: stop2 });
-        await this.callback(term);
-      });
-    } else if (geneSearch.chr && Number.isInteger(geneSearch.start) && Number.isInteger(geneSearch.stop)) {
-      const { chr } = geneSearch;
-      let { start, stop } = geneSearch;
-      if (geneSearch.actualposition?.len <= 1) {
-        start = geneSearch.actualposition.position;
-        stop = start + 1;
-      }
-      const term = this.makeTerm({ chr, start, stop });
-      await this.callback(term);
-    } else {
-      throw new Error("invalid gene search input");
-    }
-  }
-  makeTerm(opts) {
-    const { chr, start, stop } = opts;
-    if (!chr || !Number.isInteger(start) || !Number.isInteger(stop)) throw new Error("invalid coordinate");
-    const unit = getDNAMethUnit("region", this.app.vocabApi);
-    const term = {
-      chr,
-      start,
-      stop,
-      type: DNA_METHYLATION,
-      unit,
-      genomicFeatureType: "region"
-    };
-    return term;
-  }
-};
-
-export {
-  SearchHandler
-};
-//# sourceMappingURL=chunk-2XOBD4ZZ.js.map

package/dist/chunk-4DXQJGJ7.js

@@ -1,31 +0,0 @@
-import {
-  IN_frame,
-  OUT_frame
-} from "./chunk-IZUYLFOX.js";
-
-// src/spliceevent.exonskip.getdefault.js
-function spliceevent_exonskip_getdefault_default(events) {
-  let evt2showidx = 0;
-  for (let i = 1; i < events.length; i++) {
-    const e = events[i];
-    const e2show = events[evt2showidx];
-    if (e.isskipexon && e2show.isaltexon) {
-      evt2showidx = i;
-      continue;
-    }
-    if (e.frame == OUT_frame && e2show.framenocheck) {
-      evt2showidx = i;
-      continue;
-    }
-    if (e.frame == IN_frame && e2show.frame != IN_frame) {
-      evt2showidx = i;
-      continue;
-    }
-  }
-  return evt2showidx;
-}
-
-export {
-  spliceevent_exonskip_getdefault_default
-};
-//# sourceMappingURL=chunk-4DXQJGJ7.js.map

package/dist/chunk-5UO7MKCO.js

@@ -1,59 +0,0 @@
-import {
-  plotColor
-} from "./chunk-IZUYLFOX.js";
-
-// plots/scatter/settings/defaults.ts
-function getDefaultScatterSettings(opts = {}) {
-  const overrides = opts?.overrides || {};
-  const defaults = {
-    size: 0.8,
-    minShapeSize: 0.5,
-    maxShapeSize: 4,
-    scaleDotOrder: "Ascending",
-    refSize: 0.8,
-    svgw: 600,
-    svgh: 600,
-    svgd: 600,
-    axisTitleFontSize: 16,
-    showAxes: true,
-    showRef: true,
-    opacity: 0.6,
-    defaultColor: plotColor,
-    regression: "None",
-    fov: 50,
-    threeSize: 5e-3,
-    threeFOV: 70,
-    //ColorScale settings
-    colorScaleMode: "auto",
-    colorScalePercentile: 95,
-    colorScaleMinFixed: null,
-    colorScaleMaxFixed: null,
-    //3D Plot settings
-    showContour: false,
-    colorContours: false,
-    contourBandwidth: 30,
-    contourThresholds: 10,
-    duration: 500,
-    useGlobalMinMax: true,
-    saveZoomTransform: false,
-    // Axis scale settings
-    minXScale: null,
-    maxXScale: null,
-    minYScale: null,
-    maxYScale: null,
-    itemLabel: opts?.singleCellPlot ? "Cell" : "Sample",
-    maxTooltipRows: 5
-  };
-  return Object.assign(defaults, overrides);
-}
-var maxSvgSamplesCutoff = 2e4;
-var noExpColor = "#F5F5F5";
-var expColor = "#ff000d";
-
-export {
-  getDefaultScatterSettings,
-  maxSvgSamplesCutoff,
-  noExpColor,
-  expColor
-};
-//# sourceMappingURL=chunk-5UO7MKCO.js.map

package/dist/chunk-5UO7MKCO.js.map

@@ -1,7 +0,0 @@
-{
-  "version": 3,
-  "sources": ["../plots/scatter/settings/defaults.ts"],
-  "sourcesContent": ["import type { Settings } from './Settings.js'\nimport { plotColor } from '#shared/common.js'\n\nexport function getDefaultScatterSettings(opts: any = {}): Settings {\n\tconst overrides = opts?.overrides || {}\n\tconst defaults: Settings = {\n\t\tsize: 0.8,\n\t\tminShapeSize: 0.5,\n\t\tmaxShapeSize: 4,\n\t\tscaleDotOrder: 'Ascending',\n\t\trefSize: 0.8,\n\t\tsvgw: 600,\n\t\tsvgh: 600,\n\t\tsvgd: 600,\n\t\taxisTitleFontSize: 16,\n\t\tshowAxes: true,\n\t\tshowRef: true,\n\t\topacity: 0.6,\n\t\tdefaultColor: plotColor,\n\t\tregression: 'None',\n\t\tfov: 50,\n\t\tthreeSize: 0.005,\n\t\tthreeFOV: 70,\n\t\t//ColorScale settings\n\t\tcolorScaleMode: 'auto',\n\t\tcolorScalePercentile: 95,\n\t\tcolorScaleMinFixed: null,\n\t\tcolorScaleMaxFixed: null,\n\t\t//3D Plot settings\n\t\tshowContour: false,\n\t\tcolorContours: false,\n\t\tcontourBandwidth: 30,\n\t\tcontourThresholds: 10,\n\t\tduration: 500,\n\t\tuseGlobalMinMax: true,\n\t\tsaveZoomTransform: false,\n\t\t// Axis scale settings\n\t\tminXScale: null,\n\t\tmaxXScale: null,\n\t\tminYScale: null,\n\t\tmaxYScale: null,\n\t\titemLabel: opts?.singleCellPlot ? 'Cell' : 'Sample',\n\t\tmaxTooltipRows: 5\n\t}\n\n\treturn Object.assign(defaults, overrides)\n}\n\nexport const maxSvgSamplesCutoff = 20000 // if map is greater than cutoff, switch from svg to canvas rendering\nexport const noExpColor = '#F5F5F5' //light gray\nexport const expColor = '#ff000d' //default color for gene expression\n"],
-  "mappings": ";;;;;AAGO,SAAS,0BAA0B,OAAY,CAAC,GAAa;AACnE,QAAM,YAAY,MAAM,aAAa,CAAC;AACtC,QAAM,WAAqB;AAAA,IAC1B,MAAM;AAAA,IACN,cAAc;AAAA,IACd,cAAc;AAAA,IACd,eAAe;AAAA,IACf,SAAS;AAAA,IACT,MAAM;AAAA,IACN,MAAM;AAAA,IACN,MAAM;AAAA,IACN,mBAAmB;AAAA,IACnB,UAAU;AAAA,IACV,SAAS;AAAA,IACT,SAAS;AAAA,IACT,cAAc;AAAA,IACd,YAAY;AAAA,IACZ,KAAK;AAAA,IACL,WAAW;AAAA,IACX,UAAU;AAAA;AAAA,IAEV,gBAAgB;AAAA,IAChB,sBAAsB;AAAA,IACtB,oBAAoB;AAAA,IACpB,oBAAoB;AAAA;AAAA,IAEpB,aAAa;AAAA,IACb,eAAe;AAAA,IACf,kBAAkB;AAAA,IAClB,mBAAmB;AAAA,IACnB,UAAU;AAAA,IACV,iBAAiB;AAAA,IACjB,mBAAmB;AAAA;AAAA,IAEnB,WAAW;AAAA,IACX,WAAW;AAAA,IACX,WAAW;AAAA,IACX,WAAW;AAAA,IACX,WAAW,MAAM,iBAAiB,SAAS;AAAA,IAC3C,gBAAgB;AAAA,EACjB;AAEA,SAAO,OAAO,OAAO,UAAU,SAAS;AACzC;AAEO,IAAM,sBAAsB;AAC5B,IAAM,aAAa;AACnB,IAAM,WAAW;",
-  "names": []
-}

package/dist/chunk-5X6CDEMT.js

@@ -1,55 +0,0 @@
-import {
-  addGeneSearchbox,
-  getGEunit,
-  getSelectedSampleTypes,
-  renderSampleTypeSelect,
-  table2col
-} from "./chunk-NQDF3U2C.js";
-import {
-  Menu
-} from "./chunk-ELJX3QIQ.js";
-import {
-  TermTypes
-} from "./chunk-IZUYLFOX.js";
-
-// termdb/handlers/geneExpression.ts
-var SearchHandler = class {
-  init(opts) {
-    this.callback = opts.callback;
-    this.app = opts.app;
-    const holder = opts.holder.append("div").style("padding", "10px 0px");
-    this.querySampleTypes = this.app.vocabApi.termdbConfig?.queries.geneExpression.sampleTypes;
-    if (Array.isArray(this.querySampleTypes) && this.querySampleTypes.length >= 2) {
-      const sampleTypeDiv = holder.append("div");
-      const table = table2col({ holder: sampleTypeDiv, margin: "0px 0px 15px 0px" });
-      const [td1, td2] = table.addRow();
-      td1.text("Sample Type");
-      this.sampleTypeSelect = renderSampleTypeSelect(td2, this.querySampleTypes, this.app.vocabApi.termdbConfig);
-    }
-    const geneSearch = addGeneSearchbox({
-      tip: new Menu({ padding: "0px" }),
-      genome: opts.genomeObj,
-      row: holder,
-      searchOnly: "gene",
-      callback: () => this.selectGene(geneSearch)
-    });
-  }
-  async selectGene(geneSearch) {
-    const gene = geneSearch?.geneSymbol;
-    if (!gene) throw new Error("No gene selected");
-    const sampleTypes = getSelectedSampleTypes(this.sampleTypeSelect) || this.querySampleTypes;
-    if (this.sampleTypeSelect && !sampleTypes?.length) {
-      window.alert("Must select at least one sample type");
-      return;
-    }
-    const unit = getGEunit(this.app.vocabApi);
-    const name = `${gene} ${unit}`;
-    const term = { gene, name, type: TermTypes.GENE_EXPRESSION, sampleTypes };
-    this.callback(term);
-  }
-};
-
-export {
-  SearchHandler
-};
-//# sourceMappingURL=chunk-5X6CDEMT.js.map

package/dist/chunk-6BG5G6SC.js

@@ -1,397 +0,0 @@
-import {
-  CNVkey2order
-} from "./chunk-KUHCBPKU.js";
-import {
-  TermTypes,
-  colorScaleMap,
-  dtcnv,
-  dtfusionrna,
-  dtgeneexpression,
-  dtsnvindel,
-  dtsv
-} from "./chunk-IZUYLFOX.js";
-import {
-  convertUnits
-} from "./chunk-W5J3LTYS.js";
-
-// plots/matrix/matrix.cells.js
-function setNumericCellProps(cell, tw, anno, value, s, t, self, width, height, dx, dy, i) {
-  const key = anno.key;
-  const values = tw.term.values || {};
-  cell.label = "label" in anno ? anno.label : values[key]?.label ? values[key].label : key;
-  cell.fill = self.config.settings.matrix.twSpecificSettings?.[tw.$id]?.[key]?.color || anno.color || values[anno.key]?.color || self.data.refs.byTermId?.[tw.$id]?.bins?.find((b) => anno.key == b.name)?.color;
-  cell.order = t.ref.bins ? t.ref.bins.findIndex((bin) => bin.name == key) : 0;
-  if (tw.q?.mode == "continuous") {
-    const twSpecificSettings = self.config.settings.matrix.twSpecificSettings;
-    if (!twSpecificSettings[tw.$id]) twSpecificSettings[tw.$id] = {};
-    const twSettings = twSpecificSettings[tw.$id];
-    if (!twSettings.contBarH) twSettings.contBarH = s.barh;
-    if (!("gap" in twSettings)) twSettings.contBarGap = 4;
-    const specialValue = tw.term.values?.[cell.key];
-    if (specialValue?.uncomputable) {
-      cell.x = cell.totalIndex * dx + cell.grpIndex * s.colgspace;
-      cell.y = height * i;
-      cell.height = twSettings.contBarH;
-      cell.fill = "transparent";
-      const group = tw.legend?.group || tw.$id;
-      return;
-    }
-    cell.fill = self.config.settings.matrix.twSpecificSettings?.[tw.$id]?.contBarColor || "#555";
-    if (s.transpose) {
-      cell.height = t.scale(cell.key);
-      cell.x = twSettings.contBarGap;
-    } else {
-      const vc = cell.term.valueConversion;
-      let renderV = vc ? cell.key * vc.scaleFactor : cell.key;
-      if (tw.q.convert2ZScore) {
-        renderV = (renderV - t.mean) / t.std;
-        cell.fill = renderV > 0 ? "#FF6666" : "#6666FF";
-        cell.zscoreLabel = ` (Z-score: ${renderV.toFixed(2)})`;
-      }
-      cell.label = "label" in anno ? anno.label : values[key]?.label ? values[key].label : tw.term.unit ? `${cell.key.toFixed(2)} ${tw.term.unit}` : cell.key.toFixed(2);
-      cell.height = renderV >= 0 ? t.scales.pos(renderV) : t.scales.neg(renderV);
-      cell.x = cell.totalIndex * dx + cell.grpIndex * s.colgspace;
-      cell.y = renderV >= 0 ? t.counts.posMaxHt + twSettings.contBarGap - cell.height : t.counts.posMaxHt + twSettings.contBarGap;
-      cell.convertedValueLabel = !vc ? "" : convertUnits(cell.key, vc.fromUnit, vc.toUnit, vc.scaleFactor);
-    }
-  } else {
-    cell.x = cell.totalIndex * dx + cell.grpIndex * s.colgspace;
-    cell.y = height * i;
-    const group = tw.legend?.group || tw.$id;
-    return { ref: t.ref, group, value: key, entry: { key, label: cell.label, fill: cell.fill } };
-  }
-}
-function setSurvivalCellProps(cell, tw, anno, value, s, t, self, width, height, dx, dy, i) {
-  const key = tw.q?.mode == "continuous" ? anno.value : anno.key;
-  cell.key = key;
-  cell.label = tw.q?.mode == "continuous" ? tw.term.unit ? `${key} ${tw.term.unit}` : key : tw.term.values?.[key].label ? tw.term.values?.[key].label : "Exit code: " + key;
-  cell.fill = self.config.settings.matrix.twSpecificSettings?.[tw.$id]?.[key]?.color || (key == 1 ? "#a1a3a6" : "#a3c88b");
-  cell.order = 0;
-  if (tw.q?.mode == "continuous") {
-    const twSpecificSettings = self.config.settings.matrix.twSpecificSettings;
-    if (!twSpecificSettings[tw.$id]) twSpecificSettings[tw.$id] = {};
-    const twSettings = twSpecificSettings[tw.$id];
-    if (!twSettings.contBarH) twSettings.contBarH = s.barh;
-    if (!("gap" in twSettings)) twSettings.contBarGap = 4;
-    cell.exitCodeKey = tw.term.values?.[anno.key].label || "Exit code: " + anno.key;
-    cell.fill = self.config.settings.matrix.twSpecificSettings?.[tw.$id]?.[anno.key]?.color || (anno.key == 1 ? "#a1a3a6" : "#a3c88b");
-    if (s.transpose) {
-      cell.height = t.scale(cell.key);
-      cell.x = twSettings.contBarGap;
-    } else {
-      const vc = cell.term.valueConversion;
-      let renderV = vc ? cell.key * vc.scaleFactor : cell.key;
-      if (tw.q.convert2ZScore) {
-        renderV = (renderV - t.mean) / t.std;
-        cell.zscoreLabel = ` (Z-score: ${renderV.toFixed(2)})`;
-      }
-      cell.label = tw.term.unit ? `${cell.key.toFixed(2)} ${tw.term.unit}` : cell.key.toFixed(2);
-      cell.height = renderV >= 0 ? t.scales.pos(renderV) : t.scales.neg(renderV);
-      cell.x = cell.totalIndex * dx + cell.grpIndex * s.colgspace;
-      cell.y = renderV >= 0 ? t.counts.posMaxHt + twSettings.contBarGap - cell.height : t.counts.posMaxHt + twSettings.contBarGap;
-      cell.convertedValueLabel = !vc ? "" : convertUnits(cell.key, vc.fromUnit, vc.toUnit, vc.scaleFactor);
-    }
-  } else {
-    const vc = cell.term.valueConversion;
-    cell.timeToEventKey = vc ? convertUnits(anno.value, vc.fromUnit, vc.toUnit, vc.scaleFactor) : anno.value.toFixed(2);
-    cell.x = cell.totalIndex * dx + cell.grpIndex * s.colgspace;
-    cell.y = height * i;
-    const group = tw.legend?.group || tw.$id;
-    return { ref: t.ref, group, value: key, entry: { key, label: cell.label, fill: cell.fill } };
-  }
-}
-function setCategoricalCellProps(cell, tw, anno, value, s, t, self, width, height, dx, dy, i) {
-  const values = tw.term.values || {};
-  const key = anno.key;
-  cell.label = "label" in anno ? anno.label : values[key]?.label ? values[key].label : key;
-  cell.fill = self.config.settings.matrix.twSpecificSettings?.[tw.$id]?.[key]?.color || anno.color || values[anno.key]?.color;
-  cell.x = cell.totalIndex * dx + cell.grpIndex * s.colgspace;
-  cell.y = height * i;
-  const group = tw.legend?.group || tw.$id;
-  return { ref: t.ref, group, value: anno.key, entry: { key, label: cell.label, fill: cell.fill } };
-}
-function setMultivalueCellProps(cell, tw, anno, value, s, t, self, width, height, dx, dy, i) {
-  const key = value?.key ?? anno.key;
-  const values = tw.term.values || {};
-  cell.key = key;
-  cell.label = values[key]?.label || key;
-  cell.fill = self.config.settings.matrix.twSpecificSettings?.[tw.$id]?.[key]?.color || values[key]?.color;
-  cell.x = cell.totalIndex * dx + cell.grpIndex * s.colgspace;
-  cell.y = height * i;
-  const group = tw.legend?.group || tw.$id;
-  return { ref: t.ref, group, value: key, entry: { key, label: cell.label, fill: cell.fill } };
-}
-function setGeneVariantCellProps(cell, tw, anno, value, s, t, self, width, height, dx, dy, i) {
-  if (tw.q?.type == "predefined-groupset" || tw.q?.type == "custom-groupset") {
-    cell.label = value;
-    const groupset = tw.q.type == "custom-groupset" ? tw.q.customset : tw.term.groupsetting.lst[tw.q.predefined_groupset_idx];
-    if (!groupset) throw "groupset not found";
-    const group = groupset.groups.find((group2) => group2.name == value);
-    if (!group) throw "group not found";
-    cell.fill = group.color;
-    cell.x = cell.totalIndex * dx + cell.grpIndex * s.colgspace;
-    cell.y = height * i;
-    return {
-      ref: t.ref,
-      group: tw.legend?.group || tw.$id,
-      value,
-      entry: { key: anno.key, label: cell.label, fill: cell.fill }
-    };
-  } else {
-    const values = anno.renderedValues || anno.filteredValues || anno.values || [anno.value];
-    const colorFromq = tw.q?.values && tw.q?.values[value.class]?.color;
-    cell.label = value.label || self.mclass[value.class].label;
-    cell.fill = self.getValueColor?.(value.value) || colorFromq || value.color || self.mclass[value.class]?.color;
-    cell.class = value.class;
-    cell.value = value;
-    const colw = self.dimensions.colw;
-    if (s.cellEncoding == "") {
-      cell.height = s.rowh / values.length;
-      cell.width = colw;
-      cell.x = cell.totalIndex * dx + cell.grpIndex * s.colgspace;
-      cell.y = height * i;
-    } else if (value.dt == dtsnvindel || value.dt == dtfusionrna || value.dt == dtsv) {
-      if (s.cellEncoding == "single") {
-        cell.height = s.rowh;
-        cell.width = colw;
-        cell.x = cell.totalIndex * dx + cell.grpIndex * s.colgspace;
-        cell.y = 0;
-      } else {
-        const divisor = 3;
-        cell.height = s.rowh / divisor;
-        cell.width = colw;
-        cell.x = cell.totalIndex * dx + cell.grpIndex * s.colgspace;
-        cell.y = height * 0.33333;
-        if (s.oncoPrintSNVindelCellBorder) {
-          cell.border = true;
-        }
-      }
-    } else if (value.dt == dtcnv || value.dt == dtgeneexpression) {
-      cell.height = s.rowh;
-      cell.width = colw;
-      cell.x = cell.totalIndex * dx + cell.grpIndex * s.colgspace;
-      cell.y = 0;
-    } else {
-      throw `cannot set cell props for dt='${value.dt}'`;
-    }
-    if (value.class == "Blank" || value.class == "WT") {
-      cell.label = `${self.dt2label[value.dt]} ${cell.label}`;
-    }
-    const byDt = self.state.termdbConfig.assayAvailability?.byDt;
-    const order = CNVkey2order(value.class);
-    if (value.dt == dtcnv) {
-      if (t.scales && value.class.startsWith("CNV_")) {
-        const {
-          /*maxLoss,*/
-          maxGain,
-          minLoss,
-          /*minGain,*/
-          absMax
-        } = t.scales;
-        value.scaledValue = value.value < 0 ? value.value / -absMax : value.value / absMax;
-        cell.fill = value.value < 0 ? t.scales.loss(value.scaledValue) : t.scales.gain(value.scaledValue);
-        return {
-          ref: t.ref,
-          group: "CNV",
-          value: value.class,
-          order: -1,
-          entry: {
-            key: value.class,
-            label: cell.label,
-            scale: value.class == "CNV_loss" ? t.scales.loss : t.scales.gain,
-            domain: t.domain ? t.domain : value.class == "CNV_loss" ? [0, -minLoss] : [0, maxGain],
-            colors: t.range,
-            scales: value.dt == 4 && t.scales,
-            minLabel: 0,
-            maxLabel: value.class == "CNV_loss" ? minLoss : maxGain,
-            order,
-            dt: value.dt,
-            origin: value.origin
-          }
-        };
-      } else {
-        const group = "CNV";
-        return {
-          ref: t.ref,
-          group,
-          value: value.class,
-          order: -1,
-          entry: { key: value.class, label: cell.label, fill: cell.fill, order, dt: value.dt, origin: value.origin }
-        };
-      }
-    } else if (value.dt == dtfusionrna && byDt?.[dtfusionrna]) {
-      const group = "Fusion RNA";
-      return {
-        ref: t.ref,
-        group,
-        value: value.class,
-        order: -1,
-        entry: { key: value.class, label: cell.label, fill: cell.fill, order, dt: value.dt, origin: value.origin }
-      };
-    } else if (value.dt == dtsv && byDt?.[dtsv]) {
-      const group = "Structural Variation";
-      return {
-        ref: t.ref,
-        group,
-        value: value.class,
-        order: -1,
-        entry: { key: value.class, label: cell.label, fill: cell.fill, order, dt: value.dt, origin: value.origin }
-      };
-    } else if (value.dt == dtgeneexpression) {
-      return {
-        ref: t.ref,
-        group: self.config.settings.hierCluster?.termGroupName || "Gene Expression",
-        value: value.class,
-        order: -1,
-        entry: {
-          key: value.class,
-          label: "",
-          scale: self.geneExpValues.scale,
-          domain: [0, 0.5, 1],
-          minLabel: self.geneExpValues.min,
-          maxLabel: self.geneExpValues.max,
-          order,
-          dt: value.dt,
-          origin: value.origin
-        }
-      };
-    } else {
-      const controlLabels = self.settings.matrix.controlLabels;
-      const group = tw.legend?.group || (value.origin ? `${value.origin[0].toUpperCase() + value.origin.slice(1)} ${controlLabels.Mutations}` : controlLabels.Mutations);
-      return {
-        ref: t.ref,
-        group,
-        value: value.class,
-        order: -2,
-        entry: { key: value.class, label: cell.label, fill: cell.fill, order, dt: value.dt, origin: value.origin }
-      };
-    }
-  }
-}
-function setHierClusterCellProps(cell, tw, anno, value, s, t, self, width, height, dx, dy, i) {
-  const values = anno.renderedValues || anno.filteredValues || anno.values || [anno.value];
-  cell.label = value.value;
-  cell.fill = self.getValueColor?.(value.value);
-  cell.value = value;
-  const colw = self.dimensions.colw;
-  cell.height = s.clusterRowh;
-  cell.width = colw;
-  cell.x = cell.totalIndex * dx + cell.grpIndex * s.colgspace;
-  cell.y = height * i;
-  const hierCluster = self.config.settings.hierCluster;
-  let groupName;
-  if (hierCluster?.termGroupName) {
-    groupName = hierCluster.termGroupName;
-  } else if (tw.term.type == "geneExpression") {
-    groupName = "Gene Expression";
-    const unit = self.app.vocabApi.termdbConfig.queries?.geneExpression?.unit;
-    if (hierCluster?.zScoreTransformation) groupName += " (Z-score)";
-    else if (unit) groupName += ` (${unit})`;
-  } else if (tw.term.type == "metaboliteIntensity") {
-    groupName = "Intensity";
-  } else if (tw.term.type == "proteomeAbundance") {
-    groupName = "Protein Abundance";
-  } else {
-    groupName = "Heatmap color scale";
-  }
-  return {
-    ref: t.ref,
-    group: groupName,
-    order: -1,
-    entry: {
-      label: "",
-      scale: self.hierClusterValues.scale,
-      domain: colorScaleMap[self.settings.hierCluster.colorScale].domain,
-      minLabel: self.hierClusterValues.min,
-      maxLabel: self.hierClusterValues.max,
-      order: 0,
-      dt: value.dt
-    }
-  };
-}
-function getEmptyCell(cellTemplate, s, d) {
-  const cell = Object.assign({}, cellTemplate);
-  cell.fill = s.cellbg;
-  cell.height = s.rowh;
-  cell.width = d.colw;
-  cell.x = cell.totalIndex * d.dx + cell.grpIndex * s.colgspace;
-  cell.y = 0;
-  return cell;
-}
-var setCellProps = {
-  // some of these have been replaced by addOns{setCellProps} in matrix.xtw.ts,
-  // but leaving here for now since non-classed tw's may still use these
-  categorical: setCategoricalCellProps,
-  condition: setCategoricalCellProps,
-  multivalue: setMultivalueCellProps,
-  integer: setNumericCellProps,
-  float: setNumericCellProps,
-  survival: setSurvivalCellProps,
-  geneVariant: setGeneVariantCellProps,
-  hierCluster: setHierClusterCellProps,
-  [TermTypes.GENE_EXPRESSION]: setNumericCellProps,
-  [TermTypes.METABOLITE_INTENSITY]: setNumericCellProps,
-  [TermTypes.PROTEOME_ABUNDANCE]: setNumericCellProps
-  //termCollection: setTermCollectionCellProps
-};
-var maySetEmptyCell = {
-  geneVariant: setVariantEmptyCell,
-  integer: setNumericEmptyCell,
-  float: setNumericEmptyCell,
-  categorical: setDefaultEmptyCell,
-  condition: setDefaultEmptyCell,
-  multivalue: setDefaultEmptyCell,
-  survival: setNumericEmptyCell,
-  [TermTypes.GENE_EXPRESSION]: setNumericEmptyCell,
-  [TermTypes.METABOLITE_INTENSITY]: setNumericEmptyCell,
-  [TermTypes.PROTEOME_ABUNDANCE]: setNumericEmptyCell
-};
-function setVariantEmptyCell(siblingCells, cellTemplate, s, d) {
-  if (siblingCells.find((c) => c.value.dt == dtcnv)) return;
-  const cell = Object.assign({}, cellTemplate);
-  cell.fill = s.cellbg;
-  cell.height = s.rowh;
-  cell.width = d.colw;
-  cell.x = cell.totalIndex * d.dx + cell.grpIndex * s.colgspace;
-  cell.y = 0;
-  return cell;
-}
-function setNumericEmptyCell(siblingCells, cellTemplate, s, d, self) {
-  const q = cellTemplate.tw.q;
-  if (q.mode != "continuous") {
-    if (siblingCells.length) return;
-    setDefaultEmptyCell(siblingCells, cellTemplate, s, d);
-  } else {
-    if (q?.mode != "continuous") return;
-    const twSpecificSettings = self.config.settings.matrix.twSpecificSettings;
-    const twSettings = twSpecificSettings[cellTemplate.$id];
-    const h = twSettings ? twSettings.contBarH + 2 * twSettings.contBarGap : s.rowh;
-    if (cellTemplate.height >= h) return;
-    const cell = Object.assign({}, cellTemplate);
-    cell.fill = s.cellbg;
-    cell.height = h || s.rowh;
-    cell.width = d.colw;
-    cell.x = cell.totalIndex * d.dx + cell.grpIndex * s.colgspace;
-    cell.y = 0;
-    return cell;
-  }
-}
-function setDefaultEmptyCell(siblingCells, cellTemplate, s, d) {
-  if (siblingCells.length) return;
-  const cell = Object.assign({}, cellTemplate);
-  cell.fill = s.cellbg;
-  cell.height = s.rowh;
-  cell.width = d.colw;
-  cell.x = cell.totalIndex * d.dx + cell.grpIndex * s.colgspace;
-  cell.y = 0;
-  return cell;
-}
-
-export {
-  setGeneVariantCellProps,
-  setHierClusterCellProps,
-  getEmptyCell,
-  setCellProps,
-  maySetEmptyCell
-};
-//# sourceMappingURL=chunk-6BG5G6SC.js.map