@sjcrh/proteinpaint-client 2.205.0 → 2.206.0

package/dist/chunk-2GLNPB5J.js

@@ -1,203 +0,0 @@
-import {
-  tkt
-} from "./chunk-J7JDCNLU.js";
-import {
-  stratinput
-} from "./chunk-PF4DSFDR.js";
-import {
-  stratify_default
-} from "./chunk-HDTFYTEL.js";
-
-// src/vcf.tkconvert.js
-function vcf2dstk(arg) {
-  const ds = {
-    id2vcf: {},
-    label: arg.name || "Unnamed VCF file"
-  };
-  let vcfobj;
-  if (arg.file) {
-    const id = Math.random().toString();
-    vcfobj = {
-      file: arg.file,
-      indexURL: arg.indexURL,
-      vcfid: id
-    };
-    ds.id2vcf[id] = vcfobj;
-  } else if (arg.url) {
-    const id = Math.random().toString();
-    vcfobj = {
-      url: arg.url,
-      indexURL: arg.indexURL,
-      vcfid: id
-    };
-    ds.id2vcf[id] = vcfobj;
-  } else {
-    return ["no .file or .url"];
-  }
-  vcfobj.headernotloaded = true;
-  if (arg.samplenamemap) {
-    vcfobj.samplenamemap = arg.samplenamemap;
-  }
-  if (arg.variant2img) {
-    if (!arg.variant2img.path) return [".path missing from .variant2img{}"];
-  }
-  const tk = {
-    type: tkt.ds,
-    // to be loaded by loadvcftk() as a custom track, rather than "/dsdata" for official ds
-    isvcf: true,
-    name: ds.label,
-    ds,
-    populationfrequencyfilter: arg.populationfrequencyfilter,
-    vcfinfofilter: arg.vcfinfofilter,
-    itemlabelname: arg.itemlabelname,
-    viewrangeupperlimit: arg.viewrangeupperlimit,
-    variant2img: arg.variant2img,
-    axisheight: arg.axisheight
-  };
-  if (arg.url4variant) {
-    const err = check_url4variant(arg.url4variant);
-    if (err) return [".url4variant error: " + err];
-    tk.url4variant = arg.url4variant;
-  }
-  if (arg.button4variant) {
-    const err = check_button4variant(arg.button4variant);
-    if (err) return [".button4variant error: " + err];
-    tk.button4variant = arg.button4variant;
-  }
-  if (arg.sampleannotation) {
-    const sn = arg.sampleannotation;
-    if (!sn.annotation) return [".annotation{} missing from .sampleannotation"];
-    if (sn.levels) {
-      if (!Array.isArray(sn.levels)) return [".sampleannotation.levels should be array"];
-      const lst = [];
-      for (const sample in sn.annotation) {
-        const o = { sample_name: sample };
-        for (const k in sn.annotation[sample]) {
-          o[k] = sn.annotation[sample][k];
-        }
-        lst.push(o);
-      }
-      const nodes = stratinput(lst, sn.levels);
-      sn.root = stratify_default()(nodes);
-      sn.root.sum((i) => i.value);
-    }
-    if (sn.variantsunburst) {
-      if (!sn.levels) return [".levels missing when .variantsunburst is on from .sampleannotation"];
-    }
-    tk.ds.cohort = sn;
-  }
-  if (arg.vcfcohorttrack) {
-    if (!arg.vcfcohorttrack.file && !arg.vcfcohorttrack.url) return ["no .file or .url provided from .vcfcohorttrack"];
-    tk.ds.vcfcohorttrack = arg.vcfcohorttrack;
-  }
-  if (arg.germline2dvafplot) {
-    if (!arg.germline2dvafplot.individualkey) return [".individualkey missing from germline2dvafplot"];
-    if (!arg.germline2dvafplot.sampletypekey) return [".sampletypekey missing from germline2dvafplot"];
-    if (!arg.germline2dvafplot.xsampletype) return [".xsampletype missing from germline2dvafplot"];
-    if (!arg.germline2dvafplot.yleftsampletype) return [".yleftsampletype missing from germline2dvafplot"];
-    if (arg.germline2dvafplot.yrightsampletype) {
-      if (arg.germline2dvafplot.yrightsampletype == arg.germline2dvafplot.yleftsampletype)
-        return [".yrightsampletype should not be same as yleftsampletype"];
-    }
-    tk.ds.germline2dvafplot = arg.germline2dvafplot;
-  }
-  if (arg.vaf2coverageplot) {
-    if (arg.vaf2coverageplot.categorykey) {
-      if (!arg.vaf2coverageplot.categories)
-        return [".categories missing when .categorykey is in use for .vaf2coverageplot"];
-    }
-    tk.ds.vaf2coverageplot = arg.vaf2coverageplot;
-  }
-  if (arg.genotype2boxplot) {
-    if (arg.genotype2boxplot.boxplotvaluekey) {
-    } else if (arg.genotype2boxplot.sampleannotationkey) {
-      if (!tk.ds.cohort) return ["sampleannotation missing when using genotype2boxplot.sampleannotationkey"];
-      if (!tk.ds.cohort.annotation)
-        return ["sampleannotation.annotation missing when using genotype2boxplot.sampleannotationkey"];
-      let found = false;
-      for (const k in tk.ds.cohort.annotation) {
-        if (arg.genotype2boxplot.sampleannotationkey in tk.ds.cohort.annotation[k]) {
-          found = true;
-          break;
-        }
-      }
-      if (!found) return [arg.genotype2boxplot.sampleannotationkey + " not found in any sample annotation"];
-    } else {
-      return ["incomplete instruction for genotype2boxplot"];
-    }
-    tk.ds.genotype2boxplot = arg.genotype2boxplot;
-  }
-  if (arg.discardsymbolicallele) {
-    tk.ds.discardsymbolicallele = true;
-  }
-  if (arg.samplebynumericvalue) {
-    if (!arg.samplebynumericvalue.attrkey) return ["attrkey missing from samplebynumericvalue"];
-    if (!tk.ds.cohort) return ["sampleannotation missing when using samplebynumericvalue"];
-    if (!tk.ds.cohort.annotation) return ["sampleannotation.annotation missing when using samplebynumericvalue"];
-    let found = false;
-    for (const k in tk.ds.cohort.annotation) {
-      if (Number.isFinite(tk.ds.cohort.annotation[k][arg.samplebynumericvalue.attrkey])) {
-        found = true;
-        break;
-      }
-    }
-    if (!found) return ["samplebynumericvalue.attrkey not found in any sample annotation"];
-    tk.ds.samplebynumericvalue = arg.samplebynumericvalue;
-  }
-  {
-    const g = arg.genotypebynumericvalue;
-    if (g) {
-      if (!g.refref) return [tk.name + ": refref missing from genotypebynumericvalue"];
-      if (!g.refalt) return [tk.name + ": refalt missing from genotypebynumericvalue"];
-      if (!g.altalt) return [tk.name + ": altalt missing from genotypebynumericvalue"];
-      if (!g.refref.infokey) return [tk.name + ": refref.infokey missing from genotypebynumericvalue"];
-      if (!g.refalt.infokey) return [tk.name + ": refalt.infokey missing from genotypebynumericvalue"];
-      if (!g.altalt.infokey) return [tk.name + ": altalt.infokey missing from genotypebynumericvalue"];
-      if (g.refref.genotypeCountInfokey || g.refalt.genotypeCountInfokey || g.altalt.genotypeCountInfokey) {
-        if (!g.refref.genotypeCountInfokey)
-          return [tk.name + ": genotypeCountInfokey missing from genotypebynumericvalue.refref{}"];
-        if (!g.refalt.genotypeCountInfokey)
-          return [tk.name + ": genotypeCountInfokey missing from genotypebynumericvalue.refalt{}"];
-        if (!g.altalt.genotypeCountInfokey)
-          return [tk.name + ": genotypeCountInfokey missing from genotypebynumericvalue.altalt{}"];
-      }
-      tk.ds.genotypebynumericvalue = g;
-    }
-  }
-  if (arg.pointdown) {
-    tk.aboveprotein = false;
-  }
-  if (arg.dstk_novcferror) {
-    tk.dstk_novcferror = true;
-  }
-  return [null, tk];
-}
-function check_url4variant(lst) {
-  if (!Array.isArray(lst)) return "value is not an array";
-  for (const item of lst) {
-    if (!item.makeurl) {
-      return ".makeurl missing";
-    }
-    if (typeof item.makeurl != "function") {
-      return ".makeurl must be a function";
-    }
-  }
-  return false;
-}
-function check_button4variant(lst) {
-  if (!Array.isArray(lst)) return "value is not an array";
-  for (const item of lst) {
-    if (!item.makebutton) {
-      return ".makebutton missing";
-    }
-    if (typeof item.makebutton != "function") {
-      return ".makebutton must be a function";
-    }
-  }
-  return false;
-}
-
-export {
-  vcf2dstk
-};
-//# sourceMappingURL=chunk-2GLNPB5J.js.map

package/dist/chunk-2O4CS3EZ.js

@@ -1,274 +0,0 @@
-import {
-  termType2label
-} from "./chunk-RN4BOWRH.js";
-import {
-  TermTypes
-} from "./chunk-IK2BO37K.js";
-import {
-  __export
-} from "./chunk-HS5PO5ZQ.js";
-
-// plots/matrix/hierCluster.renderers.js
-var hierCluster_renderers_exports = {};
-__export(hierCluster_renderers_exports, {
-  maySetSandboxHeader: () => maySetSandboxHeader,
-  plotDendrogramHclust: () => plotDendrogramHclust,
-  renderImage: () => renderImage
-});
-function maySetSandboxHeader(appState) {
-  if (!this.dom.header) return;
-  const dataType = this.config.dataType;
-  const headerText = this.config?.headerText ? `${this.config.headerText} ` : "";
-  let title;
-  if (this.config.preBuiltPlotTitle) {
-    title = this.config.preBuiltPlotTitle;
-  } else if (this.config.appName) {
-    title = `${headerText}${this.config.appName} Clustering`;
-  } else if (dataType == TermTypes.PROTEOME_ABUNDANCE) {
-    title = this.config.assayCohortTitle ? `Protein Abundance Clustering (${this.config.assayCohortTitle})` : "Protein Abundance Clustering";
-  } else {
-    title = `${headerText}${termType2label(dataType)} Clustering`;
-  }
-  this.dom.header.text(title);
-}
-function plotDendrogramHclust(plotOnly) {
-  const d = this.dimensions;
-  const s = this.config.settings.matrix;
-  const xOffset = d.seriesXoffset;
-  const pxr = window.devicePixelRatio <= 1 ? 1 : window.devicePixelRatio;
-  const obj = this.hierClusterData.clustering;
-  const row = obj.row;
-  const col = obj.col;
-  const rowHeight = this.settings.matrix.clusterRowh, { xDendrogramHeight, yDendrogramHeight } = this.settings.hierCluster, colWidth = this.dimensions.dx;
-  if (plotOnly !== "left") {
-    if (!this.settings.hierCluster.clusterSamples) {
-      this.dom.topDendrogram.selectAll("*").remove();
-    } else {
-      const height2px = getHclustHeightScalefactor(col.height, yDendrogramHeight);
-      const height = yDendrogramHeight + 1e-7;
-      const width = Math.min(colWidth * col.inputOrder.length, s.imgWMax);
-      if (width <= 0 || height <= 0) {
-        console.warn(
-          "Skipping top dendrogram render: invalid dimensions.",
-          "This may indicate a zoom feedback loop issue.",
-          {
-            width,
-            height,
-            colWidth,
-            sampleCount: col.inputOrder.length,
-            yDendrogramHeight
-          }
-        );
-        this.dom.topDendrogram.selectAll("*").remove();
-        return;
-      }
-      const canvas = new OffscreenCanvas(width * pxr, height * pxr);
-      const ctx = canvas.getContext("2d");
-      ctx.scale(pxr, pxr);
-      ctx.translate(-d.xMin, 0);
-      ctx.imageSmoothingEnabled = false;
-      ctx.imageSmoothingQuality = "high";
-      ctx.strokeStyle = "black";
-      const mergedClusters = /* @__PURE__ */ new Map();
-      for (const [clusterid0, pair] of col.merge.entries()) {
-        const clusterid = clusterid0 + 1;
-        const children = [];
-        const childrenClusters = [];
-        let x1, x2, y1, y2;
-        if (pair.n1 < 0) {
-          const [name, columnNumber] = getLeafNumber(pair.n1, col.inputOrder, col.order);
-          x1 = colWidth * (columnNumber + 0.5);
-          y1 = yDendrogramHeight;
-          children.push({ name });
-        } else {
-          if (!mergedClusters.has(pair.n1)) throw "pair.n1 is positive but not seen before";
-          const c = mergedClusters.get(pair.n1);
-          x1 = c.x;
-          y1 = c.y;
-          children.push(...c.children);
-          childrenClusters.push(pair.n1);
-        }
-        if (pair.n2 < 0) {
-          const [name, columnNumber] = getLeafNumber(pair.n2, col.inputOrder, col.order);
-          x2 = colWidth * (columnNumber + 0.5);
-          y2 = yDendrogramHeight;
-          children.push({ name });
-        } else {
-          if (!mergedClusters.has(pair.n2)) throw "pair.n1 is positive but not seen before";
-          const c = mergedClusters.get(pair.n2);
-          x2 = c.x;
-          y2 = c.y;
-          children.push(...c.children);
-          childrenClusters.push(pair.n2);
-        }
-        const clusterY = yDendrogramHeight - col.height[clusterid0].height * height2px;
-        const highlight = this.clickedClusterIds?.includes(clusterid);
-        ctx.strokeStyle = highlight ? "red" : "black";
-        ctx.beginPath();
-        ctx.moveTo(x1, y1);
-        ctx.lineTo(x1, clusterY);
-        ctx.lineTo(x2, clusterY);
-        ctx.lineTo(x2, y2);
-        ctx.stroke();
-        ctx.closePath();
-        mergedClusters.set(clusterid, {
-          x: (x1 + x2) / 2,
-          y: clusterY,
-          children,
-          childrenClusters,
-          clusterPosition: {
-            x1,
-            x2,
-            y1,
-            y2,
-            clusterY
-          }
-        });
-      }
-      this.renderImage(
-        this.api,
-        this.dom.topDendrogram,
-        canvas,
-        width,
-        height,
-        xDendrogramHeight + 0.5 * colWidth + d.xMin,
-        s.margin.top + s.scrollHeight
-      );
-      col.mergedClusters = mergedClusters;
-    }
-  }
-  if (plotOnly !== "top") {
-    if (!this.settings.hierCluster.clusterRows) {
-      this.dom.leftDendrogram.selectAll("*").remove();
-    } else {
-      const height2px = getHclustHeightScalefactor(row.height, xDendrogramHeight);
-      const width = xDendrogramHeight + 1e-7;
-      const height = rowHeight * row.inputOrder.length;
-      const canvasWidthPx = Number.isFinite(width) && Number.isFinite(pxr) ? Math.max(0, Math.floor(width * pxr)) : 0;
-      const canvasHeightPx = Number.isFinite(height) && Number.isFinite(pxr) ? Math.max(0, Math.floor(height * pxr)) : 0;
-      if (!Number.isFinite(width) || !Number.isFinite(height) || !Number.isFinite(pxr) || width <= 0 || height <= 0 || pxr <= 0 || canvasWidthPx < 1 || canvasHeightPx < 1) {
-        console.warn(
-          "Skipping left dendrogram render: invalid dimensions.",
-          "This may indicate a zoom feedback loop issue.",
-          {
-            width,
-            height,
-            pxr,
-            canvasWidthPx,
-            canvasHeightPx,
-            rowHeight,
-            termCount: row.inputOrder.length,
-            xDendrogramHeight
-          }
-        );
-        this.dom.leftDendrogram.selectAll("*").remove();
-        return;
-      }
-      const canvas = new OffscreenCanvas(canvasWidthPx, canvasHeightPx);
-      const ctx = canvas.getContext("2d");
-      ctx.scale(pxr, pxr);
-      ctx.imageSmoothingEnabled = false;
-      ctx.imageSmoothingQuality = "high";
-      ctx.strokeStyle = "black";
-      const mergedClusters = /* @__PURE__ */ new Map();
-      for (const [clusterid0, pair] of row.merge.entries()) {
-        const clusterid = clusterid0 + 1;
-        const children = [];
-        const childrenClusters = [];
-        let x1, x2, y1, y2;
-        if (pair.n1 < 0) {
-          const [name, rowNumber] = getLeafNumber(pair.n1, row.inputOrder, row.order);
-          y1 = rowHeight * (rowNumber + 0.5);
-          x1 = xDendrogramHeight;
-          children.push({ name });
-        } else {
-          if (!mergedClusters.has(pair.n1)) throw "pair.n1 is positive but not seen before";
-          const c = mergedClusters.get(pair.n1);
-          x1 = c.x;
-          y1 = c.y;
-          children.push(...c.children);
-          childrenClusters.push(pair.n1);
-        }
-        if (pair.n2 < 0) {
-          const [name, rowNumber] = getLeafNumber(pair.n2, row.inputOrder, row.order);
-          y2 = rowHeight * (rowNumber + 0.5);
-          x2 = xDendrogramHeight;
-          children.push({ name });
-        } else {
-          if (!mergedClusters.has(pair.n2)) throw "pair.n1 is positive but not seen before";
-          const c = mergedClusters.get(pair.n2);
-          x2 = c.x;
-          y2 = c.y;
-          children.push(...c.children);
-          childrenClusters.push(pair.n2);
-        }
-        const clusterX = xDendrogramHeight - row.height[clusterid0].height * height2px;
-        const highlight = this.clickedLeftClusterIds?.includes(clusterid);
-        ctx.strokeStyle = highlight ? "red" : "black";
-        ctx.beginPath();
-        ctx.moveTo(x1, y1);
-        ctx.lineTo(clusterX, y1);
-        ctx.lineTo(clusterX, y2);
-        ctx.lineTo(x2, y2);
-        ctx.stroke();
-        ctx.closePath();
-        mergedClusters.set(clusterid, {
-          x: clusterX,
-          y: (y1 + y2) / 2,
-          children,
-          childrenClusters,
-          clusterPosition: {
-            x1,
-            x2,
-            y1,
-            y2,
-            clusterX
-          }
-        });
-      }
-      const t = this.termOrder.find((t2) => t2.grp.type == "hierCluster" || t2.grp.name == this.hcTermGroup.name);
-      const y = (
-        // t.labelOffset is commented out because it is already handled in adjustSvgDimensions
-        t.grpIndex * s.rowgspace + t.prevGrpTotalIndex * s.rowh + t.totalHtAdjustments + s.margin.top + s.scrollHeight + // left dendrogram image must be lower than the top dendrogram image height
-        yDendrogramHeight
-      );
-      this.renderImage(this.api, this.dom.leftDendrogram, canvas, width, height, 0, y);
-      row.mergedClusters = mergedClusters;
-    }
-  }
-}
-async function renderImage(componentApi, g, canvas, width, height, x, y) {
-  const sequenceId = componentApi.getSequenceId();
-  const reader = new FileReader();
-  reader.addEventListener(
-    "load",
-    () => {
-      if (componentApi.isStaleSequenceId(sequenceId)) return;
-      g.selectAll("*").remove();
-      g.append("image").attr("x", x + 0.033).attr("y", y + 0.033).attr("xlink:href", reader.result).attr("width", width).attr("height", height);
-    },
-    false
-  );
-  const blob = await canvas.convertToBlob({ quality: 1 });
-  reader.readAsDataURL(blob);
-}
-function getHclustHeightScalefactor(lst, ph) {
-  let max = lst[0].height;
-  for (const h of lst) max = Math.max(max, h.height);
-  return ph / max;
-}
-function getLeafNumber(minus, inputOrder, order) {
-  const name = inputOrder[-minus - 1];
-  if (!name) throw "minus not in inputOrder";
-  const i = order.findIndex((j) => j.name == name);
-  if (i == -1) throw "name not found in hc$order";
-  return [name, i];
-}
-
-export {
-  maySetSandboxHeader,
-  plotDendrogramHclust,
-  renderImage,
-  hierCluster_renderers_exports
-};
-//# sourceMappingURL=chunk-2O4CS3EZ.js.map