@rnacanvas/draw 12.4.3 → 12.4.5

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Files changed (2) hide show
  1. package/dist/index.js +1 -1
  2. package/package.json +2 -2
package/dist/index.js CHANGED
@@ -1 +1 @@
1
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t}toArray(){const{_a:t,_b:e,_c:r,_d:n,space:i}=this;return[t,e,r,n,i]}toHex(){const[t,e,r]=this._clamped().map(Z);return`#${t}${e}${r}`}toRgb(){const[t,e,r]=this._clamped();return`rgb(${t},${e},${r})`}toString(){return this.toHex()}xyz(){const{_a:t,_b:e,_c:r}=this.rgb(),[n,i,s]=[t,e,r].map((t=>t/255)),o=n>.04045?Math.pow((n+.055)/1.055,2.4):n/12.92,a=i>.04045?Math.pow((i+.055)/1.055,2.4):i/12.92,u=s>.04045?Math.pow((s+.055)/1.055,2.4):s/12.92,h=(.4124*o+.3576*a+.1805*u)/.95047,c=(.2126*o+.7152*a+.0722*u)/1,l=(.0193*o+.1192*a+.9505*u)/1.08883,d=h>.008856?Math.pow(h,1/3):7.787*h+16/116,f=c>.008856?Math.pow(c,1/3):7.787*c+16/116,m=l>.008856?Math.pow(l,1/3):7.787*l+16/116;return new et(d,f,m,"xyz")}_clamped(){const{_a:t,_b:e,_c:r}=this.rgb(),{max:n,min:i,round:s}=Math;return[t,e,r].map((t=>n(0,i(s(t),255))))}}class rt{constructor(...t){this.init(...t)}clone(){return new rt(this)}init(t,e){const r=Array.isArray(t)?{x:t[0],y:t[1]}:"object"==typeof t?{x:t.x,y:t.y}:{x:t,y:e};return 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Cr).use(t,e)}))}}),D(Cr,"Use"),V([$e,We,Ht,Ut,re],l("viewbox")),V([ee,ke,De,Oe],l("marker")),V(ur,l("Text")),V(Oe,l("Path")),V(Et,l("Defs")),V([ur,hr],l("Tspan")),V([Be,zt,qt,Xe],l("radius")),V(wt,l("EventTarget")),V(Pt,l("Dom")),V(Ot,l("Element")),V(Tt,l("Shape")),V([At,Xt],l("Container")),V(qt,l("Gradient")),V(Xe,l("Runner")),ct.extend([...new Set(h)]),function(t=[]){Pe.push(...[].concat(t))}([St,et,at,it,_t,Wt,we,rt]),V(Pe,{to(t){return(new xe).type(this.constructor).from(this.toArray()).to(t)},fromArray(t){return this.init(t),this},toConsumable(){return this.toArray()},morph(t,e,r,n,i){return this.fromArray(t.map((function(t,s){return n.step(t,e[s],r,i[s],i)})))}});var Ar=r(726),Er=r(358);class Tr{constructor(t,e){this.svgDoc=t,this.elements=e,new MutationObserver((t=>{t.some((t=>t.removedNodes.length>0))&&(this.elements=this.elements.filter((t=>this.svgDoc.contains(t.domNode))))})).observe(t,{childList:!0,subtree:!0})}}class jr{constructor(t,e){this.svgDoc=t,this.elementsDrawing=new Tr(t,e)}get bases(){return this.elementsDrawing.elements}set bases(t){this.elementsDrawing.elements=t}append(t){t.appendTo(this.svgDoc),this.bases.push(t)}add(t){let e=Er.Nucleobase.create(t);return this.append(e),e}}var Dr,kr,Br=r(661),Ir=r(742),Vr=function(t,e,r,n,i){if("m"===n)throw new TypeError("Private method is not writable");if("a"===n&&!i)throw new TypeError("Private accessor was defined without a setter");if("function"==typeof e?t!==e||!i:!e.has(t))throw new TypeError("Cannot write private member to an object whose class did not declare it");return"a"===n?i.call(t,r):i?i.value=r:e.set(t,r),r},Lr=function(t,e,r,n){if("a"===r&&!n)throw new TypeError("Private accessor was defined without a getter");if("function"==typeof e?t!==e||!n:!e.has(t))throw new TypeError("Cannot read private member from an object whose class did not declare it");return"m"===r?n:"a"===r?n.call(t):n?n.value:e.get(t)};class Fr{constructor(t){this.domNode=t,Dr.set(this,void 0),kr.set(this,void 0),Vr(this,Dr,new Tr(t,[]),"f"),Vr(this,kr,new MutationObserver((()=>{this.elements.forEach((t=>{this.domNode.contains(t.owner.domNode)||t.domNode.remove()}))})),"f"),Lr(this,kr,"f").observe(t,{childList:!0,subtree:!0})}get elements(){return Lr(this,Dr,"f").elements}set elements(t){Lr(this,Dr,"f").elements=t}}Dr=new WeakMap,kr=new WeakMap;var zr,Gr,Xr=function(t,e,r,n,i){if("m"===n)throw new TypeError("Private method is not writable");if("a"===n&&!i)throw new TypeError("Private accessor was defined without a setter");if("function"==typeof e?t!==e||!i:!e.has(t))throw new TypeError("Cannot write private member to an object whose class did not declare it");return"a"===n?i.call(t,r):i?i.value=r:e.set(t,r),r},Rr=function(t,e,r,n){if("a"===r&&!n)throw new TypeError("Private accessor was defined without a getter");if("function"==typeof e?t!==e||!n:!e.has(t))throw new TypeError("Cannot read private member from an object whose class did not declare it");return"m"===r?n:"a"===r?n.call(t):n?n.value:e.get(t)};class Yr{constructor(t){this.domNode=t,zr.set(this,void 0),Xr(this,zr,new Fr(t),"f")}get baseNumberings(){return Rr(this,zr,"f").elements}set baseNumberings(t){Rr(this,zr,"f").elements=t}number(t,e){let r=Ir.BaseNumbering.numbering(t,e);return this.domNode.insertBefore(r.domNode,t.domNode),Rr(this,zr,"f").elements.push(r),r}}zr=new WeakMap;class qr{constructor(t){this.domNode=t,Gr.set(this,void 0),Xr(this,Gr,new Fr(t),"f")}get baseNumberingLines(){return Rr(this,Gr,"f").elements}set baseNumberingLines(t){Rr(this,Gr,"f").elements=t}connect(t){let e=Ir.BaseNumberingLine.connecting(t);return this.domNode.insertBefore(e.domNode,t.domNode),Rr(this,Gr,"f").elements.push(e),e}}Gr=new WeakMap;var Ur,Hr=r(775),$r=function(t,e,r,n){if("a"===r&&!n)throw new TypeError("Private accessor was defined without a getter");if("function"==typeof e?t!==e||!n:!e.has(t))throw new TypeError("Cannot read private member from an object whose class did not declare it");return"m"===r?n:"a"===r?n.call(t):n?n.value:e.get(t)};class Wr{constructor(t){this.domNode=t,Ur.set(this,void 0),function(t,e,r,n,i){if("m"===n)throw new TypeError("Private method is not writable");if("a"===n&&!i)throw new TypeError("Private accessor was defined without a setter");if("function"==typeof e?t!==e||!i:!e.has(t))throw new TypeError("Cannot write private member to an object whose class did not declare it");"a"===n?i.call(t,r):i?i.value=r:e.set(t,r)}(this,Ur,new Fr(t),"f")}get baseOutlines(){return $r(this,Ur,"f").elements}set baseOutlines(t){$r(this,Ur,"f").elements=t}append(t){this.domNode.append(t.domNode),this.baseOutlines.push(t)}outline(t){let e=Hr.BaseOutline.outlining(t);return t.domNode.insertAdjacentElement("beforebegin",e.domNode),this.baseOutlines.push(e),e}}Ur=new WeakMap;var Qr=r(282);class Jr{constructor(t,e){this.svgDoc=t,this.elementsDrawing=new Tr(t,e),new MutationObserver((()=>{this.bonds.forEach((t=>{this.svgDoc.contains(t.base1.domNode)&&this.svgDoc.contains(t.base2.domNode)||t.remove()}))})).observe(t,{childList:!0,subtree:!0})}get bonds(){return this.elementsDrawing.elements}set bonds(t){this.elementsDrawing.elements=t}}class Zr{constructor(t,e){this.svgDoc=t,this.defaultValues={attributes:{stroke:"#808080","stroke-width":"1"},basePadding1:6,basePadding2:6},this.bondsDrawing=new Jr(t,e)}get primaryBonds(){return this.bondsDrawing.bonds}set primaryBonds(t){this.bondsDrawing.bonds=t}append(t){t.appendTo(this.svgDoc),this.primaryBonds.push(t)}add(t,e){let r=Qr.StraightBond.between(t,e);return this.append(r),r.set(this.defaultValues),r}}class Kr{constructor(t,e){this.svgDoc=t,this.defaultValues={attributes:{stroke:"#000000","stroke-width":"2"},basePadding1:6,basePadding2:6},this.bondsDrawing=new Jr(t,e)}get secondaryBonds(){return this.bondsDrawing.bonds}set secondaryBonds(t){this.bondsDrawing.bonds=t}append(t){t.appendTo(this.svgDoc),this.secondaryBonds.push(t)}add(t,e){let r=Qr.StraightBond.between(t,e);return this.append(r),r.set(this.defaultValues),r}}var tn,en,rn,nn,sn,on=r(854),an=function(t,e,r,n,i){if("m"===n)throw new TypeError("Private method is not writable");if("a"===n&&!i)throw new TypeError("Private accessor was defined without a setter");if("function"==typeof e?t!==e||!i:!e.has(t))throw new TypeError("Cannot write private member to an object whose class did not declare it");return"a"===n?i.call(t,r):i?i.value=r:e.set(t,r),r},un=function(t,e,r,n){if("a"===r&&!n)throw new TypeError("Private accessor was defined without a getter");if("function"==typeof e?t!==e||!n:!e.has(t))throw new TypeError("Cannot read private member from an object whose class did not declare it");return"m"===r?n:"a"===r?n.call(t):n?n.value:e.get(t)};class hn{constructor(){tn.add(this),en.set(this,void 0),rn.set(this,void 0),nn.set(this,void 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e=t-this.minX,r=this.horizontalScaling;this.domNode.setAttribute("viewBox",`${this.minX} ${this.minY} ${e} ${this.height}`),this.domNode.setAttribute("width",(r*e).toString())}get minY(){return this.domNode.viewBox.baseVal.y}set minY(t){let e=this.maxY-t,r=this.verticalScaling;this.domNode.setAttribute("viewBox",`${this.minX} ${t} ${this.width} ${e}`),this.domNode.setAttribute("height",(r*e).toString())}get maxY(){return this.minY+this.height}set maxY(t){let e=t-this.minY,r=this.verticalScaling;this.domNode.setAttribute("viewBox",`${this.minX} ${this.minY} ${this.width} ${e}`),this.domNode.setAttribute("height",(r*e).toString())}setBoundaries({minX:t,maxX:e,minY:r,maxY:n}){this.minX=t,this.maxX=e,this.minY=r,this.maxY=n}get width(){return this.domNode.viewBox.baseVal.width}set width(t){this.maxX=this.minX+t}get height(){return this.domNode.viewBox.baseVal.height}set height(t){this.maxY=this.minY+t}get horizontalScaling(){let t=this.width;return this.domNode.width.baseVal.value/t}set horizontalScaling(t){let e=this.width;this.domNode.setAttribute("width",(t*e).toString())}get verticalScaling(){let t=this.height;return this.domNode.height.baseVal.value/t}set verticalScaling(t){let e=this.height;this.domNode.setAttribute("height",(t*e).toString())}setScaling(t){this.horizontalScaling=t,this.verticalScaling=t}get horizontalClientScaling(){return new Ar.HorizontalClientScaling(this.domNode).get()}get verticalClientScaling(){return new Ar.VerticalClientScaling(this.domNode).get()}get bases(){return this.basesDrawing.bases}set bases(t){this.basesDrawing.bases=[...t]}appendBase(t){this.basesDrawing.append(t)}addBase(t){return this.basesDrawing.add(t)}number(t,e){let r=un(this,en,"f").number(t,e),n=un(this,rn,"f").connect(r);return r.displacement.magnitude=10,n.direction=(0,Br.outwardNormal)(t,...un(this,tn,"a",sn)),n.length=1.15*r.domNode.getBBox().height,[r,n]}get baseNumberings(){return un(this,en,"f").baseNumberings}set baseNumberings(t){un(this,en,"f").baseNumberings=[...t]}get baseNumberingLines(){return un(this,rn,"f").baseNumberingLines}set baseNumberingLines(t){un(this,rn,"f").baseNumberingLines=[...t]}get baseOutlines(){return un(this,nn,"f").baseOutlines}set baseOutlines(t){un(this,nn,"f").baseOutlines=[...t]}outlineBase(t){return un(this,nn,"f").outline(t)}appendBaseOutline(t){un(this,nn,"f").append(t)}get primaryBonds(){return this.primaryBondsDrawing.primaryBonds}set primaryBonds(t){this.primaryBondsDrawing.primaryBonds=[...t]}appendPrimaryBond(t){this.primaryBondsDrawing.append(t)}addPrimaryBond(t,e){return this.primaryBondsDrawing.add(t,e)}get secondaryBonds(){return this.secondaryBondsDrawing.secondaryBonds}set secondaryBonds(t){this.secondaryBondsDrawing.secondaryBonds=[...t]}appendSecondaryBond(t){this.secondaryBondsDrawing.append(t)}addSecondaryBond(t,e){return this.secondaryBondsDrawing.add(t,e)}rotate(t,e){let r=new Set(t);for(let t of this.baseNumberings)if(r.has(t.owner)){let r=Ir.BaseNumberingLine.unpadded(t);this.domNode.append(r.domNode),r.direction+=e,r.domNode.remove()}(0,Br.rotate)(t,e)}get defaultValues(){let t=this.primaryBondsDrawing,e=this.secondaryBondsDrawing;return{get primaryBonds(){return t.defaultValues},set primaryBonds(e){t.defaultValues=e},get secondaryBonds(){return e.defaultValues},set secondaryBonds(t){e.defaultValues=t}}}get contentBBox(){return this.domNode.getBBox()}setPadding(t){let e=this.contentBBox;this.setBoundaries({minX:e.x-t,maxX:e.x+e.width+t,minY:e.y-t,maxY:e.y+e.height+t})}reset(){this.domNode.innerHTML="",this.basesDrawing.bases=[],un(this,nn,"f").baseOutlines=[],this.primaryBondsDrawing.primaryBonds=[],this.secondaryBondsDrawing.secondaryBonds=[],[...this.domNode.attributes].forEach((t=>this.domNode.removeAttribute(t.name))),this.domNode.setAttribute("viewBox",`0 0 ${cn} ${ln}`),this.domNode.setAttribute("width",`${cn}`),this.domNode.setAttribute("height",`${ln}`)}serialized(){return{outerXML:this.outerXML,bases:[...this.bases].map((t=>t.serialized())),baseNumberings:[...this.baseNumberings].map((t=>t.serialized())),baseNumberingLines:[...this.baseNumberingLines].map((t=>t.serialized())),baseOutlines:[...this.baseOutlines].map((t=>t.serialized())),primaryBonds:[...this.primaryBonds].map((t=>t.serialized())),secondaryBonds:[...this.secondaryBonds].map((t=>t.serialized()))}}static deserialized(t){var e;let r=new hn,n=document.createElement("div");if(n.append(r.domNode),n.style.width="0px",n.style.height="0px",document.body.append(n),!(0,on.isNonNullObject)(t))throw new Error("Saved drawing must be an object.");let i=null!==(e=t.outerXML)&&void 0!==e?e:t.svg;if(!i)throw new Error("Saved drawing outer XML is missing.");if(!(0,on.isString)(i))throw new Error("Saved drawing outer XML must be a string.");r.outerXML=i;let s=r.domNode;(0,on.isArray)(t.bases)&&(r.bases=t.bases.map((t=>Er.Nucleobase.deserialized(t,r))));let o=[...r.bases];(0,on.isArray)(t.baseNumberings)&&(r.baseNumberings=t.baseNumberings.map((t=>Ir.BaseNumbering.deserialized(t,{domNode:s,bases:o}))));let a=[...r.baseNumberings];return(0,on.isArray)(t.baseNumberingLines)&&(r.baseNumberingLines=t.baseNumberingLines.map((t=>Ir.BaseNumberingLine.deserialized(t,{domNode:s,baseNumberings:a})))),(0,on.isArray)(t.baseOutlines)&&(r.baseOutlines=t.baseOutlines.map((t=>Hr.BaseOutline.deserialized(t,r)))),(0,on.isArray)(t.primaryBonds)&&(r.primaryBonds=t.primaryBonds.map((t=>Qr.StraightBond.deserialized(t,r)))),(0,on.isArray)(t.secondaryBonds)&&(r.secondaryBonds=t.secondaryBonds.map((t=>Qr.StraightBond.deserialized(t,r)))),r.domNode.remove(),n.remove(),r}restore(t){let e=hn.deserialized(t),r=[...e.bases],n=[...e.baseNumberings],i=[...e.baseNumberingLines],s=[...e.baseOutlines],o=[...e.primaryBonds],a=[...e.secondaryBonds];this.reset(),[...this.domNode.attributes].forEach((t=>this.domNode.removeAttribute(t.name))),[...e.domNode.attributes].forEach((t=>this.domNode.setAttribute(t.name,t.value))),[...e.domNode.childNodes].forEach((t=>this.domNode.appendChild(t))),this.bases=r,this.baseNumberings=n,this.baseNumberingLines=i,this.baseOutlines=s,this.primaryBonds=o,this.secondaryBonds=a}}en=new WeakMap,rn=new WeakMap,nn=new WeakMap,tn=new WeakSet,sn=function(){return[[...this.bases],this.secondaryBondsDrawing.secondaryBonds.map((t=>t.basePair))]};const cn=250,ln=250;var dn=r(127),fn=r(986);class mn{constructor(t){this.targetDrawing=t}draw(t,e){let r=[...t].map((t=>this.targetDrawing.addBase(t)));(0,dn.consecutivePairs)(r).forEach((t=>this.targetDrawing.addPrimaryBond(...t)));let n=[...(0,dn.parseDotBracket)(r,e)];n.forEach((t=>this.targetDrawing.addSecondaryBond(...t))),r.forEach((t=>t.bringToFront()));let i=1.87*(0,fn.mean)(r.map((t=>t.bbox.height)));(0,Br.untangle)(r,n,{spacing:i,basePairSpacing:i/2,hairpinLoopSpacing:i/2})}}var pn,gn,yn,bn,wn=function(t,e,r,n){if("a"===r&&!n)throw new TypeError("Private accessor was defined without a getter");if("function"==typeof e?t!==e||!n:!e.has(t))throw new TypeError("Cannot read private member from an object whose class did not declare it");return"m"===r?n:"a"===r?n.call(t):n?n.value:e.get(t)};class vn{constructor(t){pn.add(this),gn.set(this,void 0),function(t,e,r,n,i){if("m"===n)throw new TypeError("Private method is not writable");if("a"===n&&!i)throw new TypeError("Private accessor was defined without a setter");if("function"==typeof e?t!==e||!i:!e.has(t))throw new TypeError("Cannot write private member to an object whose class did not declare it");"a"===n?i.call(t,r):i?i.value=r:e.set(t,r)}(this,gn,t,"f")}draw(t){t.rnaComplexes.forEach((e=>{e.rnaMolecules.forEach((e=>{let r=e.sequence.map((e=>wn(this,pn,"m",yn).call(this,e,t))),n=(0,fn.mean)(r.map((t=>t.bbox.height)));wn(this,gn,"f").defaultValues.primaryBonds.attributes["stroke-width"]=""+.125*n,wn(this,gn,"f").defaultValues.primaryBonds.basePadding1=.6*n,wn(this,gn,"f").defaultValues.primaryBonds.basePadding2=.6*n,(0,dn.consecutivePairs)(r).forEach((t=>wn(this,gn,"f").addPrimaryBond(...t))),wn(this,gn,"f").defaultValues.secondaryBonds.attributes["stroke-width"]=""+.15*n,wn(this,gn,"f").defaultValues.secondaryBonds.basePadding1=.5*n,wn(this,gn,"f").defaultValues.secondaryBonds.basePadding2=.5*n,new Set(e.basePairs.map((t=>JSON.stringify(t)))).forEach((e=>wn(this,pn,"m",bn).call(this,JSON.parse(e),r,t)))}))}))}}gn=new WeakMap,pn=new WeakSet,yn=function(t,e){let r=wn(this,gn,"f").addBase(t.residueName);return t.classes.forEach((t=>{e.classes.filter((e=>e.name==t)).forEach((t=>r.setAttributes(Object.assign(Object.assign({},t),{name:void 0}))))})),r.centerPoint.x=t.x,r.centerPoint.y=t.y,r},bn=function(t,e,r){let n=e[t.residueIndex1],i=e[t.residueIndex2],s=wn(this,gn,"f").addSecondaryBond(n,i);return t.classes.forEach((t=>{r.classes.filter((e=>e.name==t)).forEach((t=>s.setAttributes(Object.assign(Object.assign({},t),{name:void 0}))))})),s}})(),n})()));
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Fr{constructor(t){this.domNode=t,Dr.set(this,void 0),kr.set(this,void 0),Vr(this,Dr,new Tr(t,[]),"f"),Vr(this,kr,new MutationObserver((()=>{this.elements.forEach((t=>{this.domNode.contains(t.owner.domNode)||t.domNode.remove()}))})),"f"),Lr(this,kr,"f").observe(t,{childList:!0,subtree:!0})}get elements(){return Lr(this,Dr,"f").elements}set elements(t){Lr(this,Dr,"f").elements=t}}Dr=new WeakMap,kr=new WeakMap;var zr,Gr,Xr=function(t,e,r,n,i){if("m"===n)throw new TypeError("Private method is not writable");if("a"===n&&!i)throw new TypeError("Private accessor was defined without a setter");if("function"==typeof e?t!==e||!i:!e.has(t))throw new TypeError("Cannot write private member to an object whose class did not declare it");return"a"===n?i.call(t,r):i?i.value=r:e.set(t,r),r},Rr=function(t,e,r,n){if("a"===r&&!n)throw new TypeError("Private accessor was defined without a getter");if("function"==typeof e?t!==e||!n:!e.has(t))throw new TypeError("Cannot read private member from an object whose class did not declare it");return"m"===r?n:"a"===r?n.call(t):n?n.value:e.get(t)};class Yr{constructor(t){this.domNode=t,zr.set(this,void 0),Xr(this,zr,new Fr(t),"f")}get baseNumberings(){return Rr(this,zr,"f").elements}set baseNumberings(t){Rr(this,zr,"f").elements=t}number(t,e){let r=Ir.BaseNumbering.numbering(t,e);return this.domNode.insertBefore(r.domNode,t.domNode),Rr(this,zr,"f").elements.push(r),r}}zr=new WeakMap;class qr{constructor(t){this.domNode=t,Gr.set(this,void 0),Xr(this,Gr,new Fr(t),"f")}get baseNumberingLines(){return Rr(this,Gr,"f").elements}set baseNumberingLines(t){Rr(this,Gr,"f").elements=t}connect(t){let e=Ir.BaseNumberingLine.connecting(t);return this.domNode.insertBefore(e.domNode,t.domNode),Rr(this,Gr,"f").elements.push(e),e}}Gr=new WeakMap;var Ur,Hr=r(775),$r=function(t,e,r,n){if("a"===r&&!n)throw new TypeError("Private accessor was defined without a getter");if("function"==typeof e?t!==e||!n:!e.has(t))throw new TypeError("Cannot read private member from an object whose class did not declare it");return"m"===r?n:"a"===r?n.call(t):n?n.value:e.get(t)};class Wr{constructor(t){this.domNode=t,Ur.set(this,void 0),function(t,e,r,n,i){if("m"===n)throw new TypeError("Private method is not writable");if("a"===n&&!i)throw new TypeError("Private accessor was defined without a setter");if("function"==typeof e?t!==e||!i:!e.has(t))throw new TypeError("Cannot write private member to an object whose class did not declare it");"a"===n?i.call(t,r):i?i.value=r:e.set(t,r)}(this,Ur,new Fr(t),"f")}get baseOutlines(){return $r(this,Ur,"f").elements}set baseOutlines(t){$r(this,Ur,"f").elements=t}append(t){this.domNode.append(t.domNode),this.baseOutlines.push(t)}outline(t){let e=Hr.BaseOutline.outlining(t);return t.domNode.insertAdjacentElement("beforebegin",e.domNode),this.baseOutlines.push(e),e}}Ur=new WeakMap;var Qr=r(282);class Jr{constructor(t,e){this.svgDoc=t,this.elementsDrawing=new Tr(t,e),new MutationObserver((()=>{this.bonds.forEach((t=>{this.svgDoc.contains(t.base1.domNode)&&this.svgDoc.contains(t.base2.domNode)||t.remove()}))})).observe(t,{childList:!0,subtree:!0})}get bonds(){return this.elementsDrawing.elements}set bonds(t){this.elementsDrawing.elements=t}}class Zr{constructor(t,e){this.svgDoc=t,this.defaultValues={attributes:{stroke:"#808080","stroke-width":"1"},basePadding1:6,basePadding2:6},this.bondsDrawing=new Jr(t,e)}get primaryBonds(){return this.bondsDrawing.bonds}set primaryBonds(t){this.bondsDrawing.bonds=t}append(t){t.appendTo(this.svgDoc),this.primaryBonds.push(t)}add(t,e){let r=Qr.StraightBond.between(t,e);return this.append(r),r.set(this.defaultValues),r}}class Kr{constructor(t,e){this.svgDoc=t,this.defaultValues={attributes:{stroke:"#000000","stroke-width":"2"},basePadding1:6,basePadding2:6},this.bondsDrawing=new Jr(t,e)}get secondaryBonds(){return this.bondsDrawing.bonds}set secondaryBonds(t){this.bondsDrawing.bonds=t}append(t){t.appendTo(this.svgDoc),this.secondaryBonds.push(t)}add(t,e){let r=Qr.StraightBond.between(t,e);return this.append(r),r.set(this.defaultValues),r}}var tn,en,rn,nn,sn,on=r(854),an=function(t,e,r,n,i){if("m"===n)throw new TypeError("Private method is not writable");if("a"===n&&!i)throw new TypeError("Private accessor was defined without a setter");if("function"==typeof e?t!==e||!i:!e.has(t))throw new TypeError("Cannot write private member to an object whose class did not declare it");return"a"===n?i.call(t,r):i?i.value=r:e.set(t,r),r},un=function(t,e,r,n){if("a"===r&&!n)throw new TypeError("Private accessor was defined without a getter");if("function"==typeof e?t!==e||!n:!e.has(t))throw new TypeError("Cannot read private member from an object whose class did not declare it");return"m"===r?n:"a"===r?n.call(t):n?n.value:e.get(t)};class hn{constructor(){tn.add(this),en.set(this,void 0),rn.set(this,void 0),nn.set(this,void 0),this.domNode=(new $e).node,this.domNode.setAttribute("viewBox",`0 0 ${cn} ${ln}`),this.domNode.setAttribute("width",`${cn}`),this.domNode.setAttribute("height",`${ln}`),this.basesDrawing=new jr(this.domNode,[]),an(this,en,new Yr(this.domNode),"f"),an(this,rn,new qr(this.domNode),"f"),an(this,nn,new Wr(this.domNode),"f"),this.primaryBondsDrawing=new Zr(this.domNode,[]),this.secondaryBondsDrawing=new Kr(this.domNode,[])}get outerXML(){return this.domNode.outerHTML}set outerXML(t){new Ar.OuterXML(this.domNode).set(t)}get innerXML(){return this.domNode.innerHTML}set innerXML(t){new Ar.InnerXML(this.domNode).set(t)}appendTo(t){t.appendChild(this.domNode)}remove(){this.domNode.remove()}get minX(){return this.domNode.viewBox.baseVal.x}set minX(t){let e=this.maxX-t,r=this.horizontalScaling;this.domNode.setAttribute("viewBox",`${t} ${this.minY} ${e} ${this.height}`),this.domNode.setAttribute("width",(r*e).toString())}get maxX(){return this.minX+this.width}set maxX(t){let e=t-this.minX,r=this.horizontalScaling;this.domNode.setAttribute("viewBox",`${this.minX} ${this.minY} ${e} ${this.height}`),this.domNode.setAttribute("width",(r*e).toString())}get minY(){return this.domNode.viewBox.baseVal.y}set minY(t){let e=this.maxY-t,r=this.verticalScaling;this.domNode.setAttribute("viewBox",`${this.minX} ${t} ${this.width} ${e}`),this.domNode.setAttribute("height",(r*e).toString())}get maxY(){return this.minY+this.height}set maxY(t){let e=t-this.minY,r=this.verticalScaling;this.domNode.setAttribute("viewBox",`${this.minX} ${this.minY} ${this.width} ${e}`),this.domNode.setAttribute("height",(r*e).toString())}setBoundaries({minX:t,maxX:e,minY:r,maxY:n}){this.minX=t,this.maxX=e,this.minY=r,this.maxY=n}get width(){return this.domNode.viewBox.baseVal.width}set width(t){this.maxX=this.minX+t}get height(){return this.domNode.viewBox.baseVal.height}set height(t){this.maxY=this.minY+t}get horizontalScaling(){let t=this.width;return this.domNode.width.baseVal.value/t}set horizontalScaling(t){let e=this.width;this.domNode.setAttribute("width",(t*e).toString())}get verticalScaling(){let t=this.height;return this.domNode.height.baseVal.value/t}set verticalScaling(t){let e=this.height;this.domNode.setAttribute("height",(t*e).toString())}setScaling(t){this.horizontalScaling=t,this.verticalScaling=t}get horizontalClientScaling(){return new Ar.HorizontalClientScaling(this.domNode).get()}get verticalClientScaling(){return new Ar.VerticalClientScaling(this.domNode).get()}get bases(){return this.basesDrawing.bases}set bases(t){this.basesDrawing.bases=[...t]}appendBase(t){this.basesDrawing.append(t)}addBase(t){return this.basesDrawing.add(t)}number(t,e){let r=un(this,en,"f").number(t,e),n=un(this,rn,"f").connect(r);return r.displacement.magnitude=10,n.direction=(0,Br.outwardNormal)(t,...un(this,tn,"a",sn)),n.length=1.15*r.domNode.getBBox().height,[r,n]}get baseNumberings(){return un(this,en,"f").baseNumberings}set baseNumberings(t){un(this,en,"f").baseNumberings=[...t]}get baseNumberingLines(){return un(this,rn,"f").baseNumberingLines}set baseNumberingLines(t){un(this,rn,"f").baseNumberingLines=[...t]}get baseOutlines(){return un(this,nn,"f").baseOutlines}set baseOutlines(t){un(this,nn,"f").baseOutlines=[...t]}outlineBase(t){return un(this,nn,"f").outline(t)}appendBaseOutline(t){un(this,nn,"f").append(t)}get primaryBonds(){return this.primaryBondsDrawing.primaryBonds}set primaryBonds(t){this.primaryBondsDrawing.primaryBonds=[...t]}appendPrimaryBond(t){this.primaryBondsDrawing.append(t)}addPrimaryBond(t,e){return this.primaryBondsDrawing.add(t,e)}get secondaryBonds(){return this.secondaryBondsDrawing.secondaryBonds}set secondaryBonds(t){this.secondaryBondsDrawing.secondaryBonds=[...t]}appendSecondaryBond(t){this.secondaryBondsDrawing.append(t)}addSecondaryBond(t,e){return this.secondaryBondsDrawing.add(t,e)}rotate(t,e){let r=new Set(t);for(let t of this.baseNumberings)if(r.has(t.owner)){let r=Ir.BaseNumberingLine.unpadded(t);this.domNode.append(r.domNode),r.direction+=e,r.domNode.remove()}(0,Br.rotate)(t,e)}get defaultValues(){let t=this.primaryBondsDrawing,e=this.secondaryBondsDrawing;return{get primaryBonds(){return t.defaultValues},set primaryBonds(e){t.defaultValues=e},get secondaryBonds(){return e.defaultValues},set secondaryBonds(t){e.defaultValues=t}}}get contentBBox(){return this.domNode.getBBox()}setPadding(t){let e=this.contentBBox;this.setBoundaries({minX:e.x-t,maxX:e.x+e.width+t,minY:e.y-t,maxY:e.y+e.height+t})}reset(){this.domNode.innerHTML="",this.basesDrawing.bases=[],un(this,nn,"f").baseOutlines=[],this.primaryBondsDrawing.primaryBonds=[],this.secondaryBondsDrawing.secondaryBonds=[],[...this.domNode.attributes].forEach((t=>this.domNode.removeAttribute(t.name))),this.domNode.setAttribute("viewBox",`0 0 ${cn} ${ln}`),this.domNode.setAttribute("width",`${cn}`),this.domNode.setAttribute("height",`${ln}`)}serialized(){return{outerXML:this.outerXML,bases:[...this.bases].map((t=>t.serialized())),baseNumberings:[...this.baseNumberings].map((t=>t.serialized())),baseNumberingLines:[...this.baseNumberingLines].map((t=>t.serialized())),baseOutlines:[...this.baseOutlines].map((t=>t.serialized())),primaryBonds:[...this.primaryBonds].map((t=>t.serialized())),secondaryBonds:[...this.secondaryBonds].map((t=>t.serialized()))}}static deserialized(t){var e;let r=new hn,n=document.createElement("div");if(n.append(r.domNode),n.style.width="0px",n.style.height="0px",document.body.append(n),!(0,on.isNonNullObject)(t))throw new Error("Saved drawing must be an object.");let i=null!==(e=t.outerXML)&&void 0!==e?e:t.svg;if(!i)throw new Error("Saved drawing outer XML is missing.");if(!(0,on.isString)(i))throw new Error("Saved drawing outer XML must be a string.");r.outerXML=i;let s=r.domNode;(0,on.isArray)(t.bases)&&(r.bases=t.bases.map((t=>Er.Nucleobase.deserialized(t,r))));let o=[...r.bases];(0,on.isArray)(t.baseNumberings)&&(r.baseNumberings=t.baseNumberings.map((t=>Ir.BaseNumbering.deserialized(t,{domNode:s,bases:o}))));let a=[...r.baseNumberings];return(0,on.isArray)(t.baseNumberingLines)&&(r.baseNumberingLines=t.baseNumberingLines.map((t=>Ir.BaseNumberingLine.deserialized(t,{domNode:s,baseNumberings:a})))),(0,on.isArray)(t.baseOutlines)&&(r.baseOutlines=t.baseOutlines.map((t=>Hr.BaseOutline.deserialized(t,r)))),(0,on.isArray)(t.primaryBonds)&&(r.primaryBonds=t.primaryBonds.map((t=>Qr.StraightBond.deserialized(t,r)))),(0,on.isArray)(t.secondaryBonds)&&(r.secondaryBonds=t.secondaryBonds.map((t=>Qr.StraightBond.deserialized(t,r)))),r.domNode.remove(),n.remove(),r}restore(t){let e=hn.deserialized(t),r=[...e.bases],n=[...e.baseNumberings],i=[...e.baseNumberingLines],s=[...e.baseOutlines],o=[...e.primaryBonds],a=[...e.secondaryBonds];this.reset(),[...this.domNode.attributes].forEach((t=>this.domNode.removeAttribute(t.name))),[...e.domNode.attributes].forEach((t=>this.domNode.setAttribute(t.name,t.value))),[...e.domNode.childNodes].forEach((t=>this.domNode.appendChild(t))),this.bases=r,this.baseNumberings=n,this.baseNumberingLines=i,this.baseOutlines=s,this.primaryBonds=o,this.secondaryBonds=a}}en=new WeakMap,rn=new WeakMap,nn=new WeakMap,tn=new WeakSet,sn=function(){return[[...this.bases],this.secondaryBondsDrawing.secondaryBonds.map((t=>t.basePair))]};const cn=250,ln=250;var dn=r(127),fn=r(986);class mn{constructor(t){this.targetDrawing=t}draw(t,e){let r=[...t].map((t=>this.targetDrawing.addBase(t)));(0,dn.consecutivePairs)(r).forEach((t=>this.targetDrawing.addPrimaryBond(...t)));let n=[...(0,dn.parseDotBracket)(r,e)];n.forEach((t=>this.targetDrawing.addSecondaryBond(...t))),r.forEach((t=>t.bringToFront()));let i=1.87*(0,fn.mean)(r.map((t=>t.bbox.height)));(0,Br.untangle)(r,n,{spacing:i,basePairSpacing:i/2,hairpinLoopSpacing:i/2})}}var pn,gn,yn,bn,wn=function(t,e,r,n){if("a"===r&&!n)throw new TypeError("Private accessor was defined without a getter");if("function"==typeof e?t!==e||!n:!e.has(t))throw new TypeError("Cannot read private member from an object whose class did not declare it");return"m"===r?n:"a"===r?n.call(t):n?n.value:e.get(t)};class vn{constructor(t){pn.add(this),gn.set(this,void 0),function(t,e,r,n,i){if("m"===n)throw new TypeError("Private method is not writable");if("a"===n&&!i)throw new TypeError("Private accessor was defined without a setter");if("function"==typeof e?t!==e||!i:!e.has(t))throw new TypeError("Cannot write private member to an object whose class did not declare it");"a"===n?i.call(t,r):i?i.value=r:e.set(t,r)}(this,gn,t,"f")}draw(t){t.rnaComplexes.forEach((e=>{e.rnaMolecules.forEach((e=>{let r=e.sequence.map((e=>wn(this,pn,"m",yn).call(this,e,t))),n=(0,fn.mean)(r.map((t=>t.bbox.height)));wn(this,gn,"f").defaultValues.primaryBonds.attributes["stroke-width"]=""+.125*n,wn(this,gn,"f").defaultValues.primaryBonds.basePadding1=.6*n,wn(this,gn,"f").defaultValues.primaryBonds.basePadding2=.6*n,(0,dn.consecutivePairs)(r).forEach((t=>wn(this,gn,"f").addPrimaryBond(...t))),wn(this,gn,"f").defaultValues.secondaryBonds.attributes["stroke-width"]=""+.15*n,wn(this,gn,"f").defaultValues.secondaryBonds.basePadding1=.5*n,wn(this,gn,"f").defaultValues.secondaryBonds.basePadding2=.5*n,new Set(e.basePairs.map((t=>JSON.stringify(t)))).forEach((e=>wn(this,pn,"m",bn).call(this,JSON.parse(e),r,t)))}))}))}}gn=new WeakMap,pn=new WeakSet,yn=function(t,e){let r=wn(this,gn,"f").addBase(t.residueName);return t.classes.forEach((t=>{e.classes.filter((e=>e.name==t)).forEach((t=>r.setAttributes(Object.assign(Object.assign({},t),{name:void 0}))))})),r.centerPoint.x=t.x,r.centerPoint.y=t.y,r},bn=function(t,e,r){let n=e[t.residueIndex1],i=e[t.residueIndex2],s=wn(this,gn,"f").addSecondaryBond(n,i);return t.classes.forEach((t=>{r.classes.filter((e=>e.name==t)).forEach((t=>s.setAttributes(Object.assign(Object.assign({},t),{name:void 0}))))})),s}})(),n})()));