@precisa-saude/fhir 0.36.0 → 0.37.1

package/dist/biomarkers.cjs

@@ -31,7 +31,7 @@
 
 
 
-var _chunkJES2ZLH5cjs = require('./chunk-JES2ZLH5.cjs');
+var _chunkBDS6CM7Fcjs = require('./chunk-BDS6CM7F.cjs');
 
 
 
@@ -65,5 +65,5 @@ var _chunkJES2ZLH5cjs = require('./chunk-JES2ZLH5.cjs');
 
 
 
-exports.BIOMARKER_DEFINITIONS = _chunkJES2ZLH5cjs.BIOMARKER_DEFINITIONS; exports.CAC_INDICATOR_CODES = _chunkJES2ZLH5cjs.CAC_INDICATOR_CODES; exports.DEXA_CATEGORIES = _chunkJES2ZLH5cjs.DEXA_CATEGORIES; exports.DEXA_INDICATOR_CODES = _chunkJES2ZLH5cjs.DEXA_INDICATOR_CODES; exports.codeToLoinc = _chunkJES2ZLH5cjs.codeToLoinc; exports.filterVisibleBiomarkers = _chunkJES2ZLH5cjs.filterVisibleBiomarkers; exports.findCodeByName = _chunkJES2ZLH5cjs.findCodeByName; exports.generateCacFullReference = _chunkJES2ZLH5cjs.generateCacFullReference; exports.generateDexaFullReference = _chunkJES2ZLH5cjs.generateDexaFullReference; exports.generateFilteredLLMReference = _chunkJES2ZLH5cjs.generateFilteredLLMReference; exports.generateLLMReference = _chunkJES2ZLH5cjs.generateLLMReference; exports.getAllCodes = _chunkJES2ZLH5cjs.getAllCodes; exports.getAllDefinitions = _chunkJES2ZLH5cjs.getAllDefinitions; exports.getAllLoincCodes = _chunkJES2ZLH5cjs.getAllLoincCodes; exports.getAllSearchPatterns = _chunkJES2ZLH5cjs.getAllSearchPatterns; exports.getBiomarkersByCategory = _chunkJES2ZLH5cjs.getBiomarkersByCategory; exports.getBiomarkersForCategories = _chunkJES2ZLH5cjs.getBiomarkersForCategories; exports.getDefinitionByCode = _chunkJES2ZLH5cjs.getDefinitionByCode; exports.getDefinitionByLoinc = _chunkJES2ZLH5cjs.getDefinitionByLoinc; exports.getDefinitionsBySex = _chunkJES2ZLH5cjs.getDefinitionsBySex; exports.getSexForCode = _chunkJES2ZLH5cjs.getSexForCode; exports.getVisibleDefinitions = _chunkJES2ZLH5cjs.getVisibleDefinitions; exports.isBiomarkerVisible = _chunkJES2ZLH5cjs.isBiomarkerVisible; exports.isCacDocument = _chunkJES2ZLH5cjs.isCacDocument; exports.isDexaDocument = _chunkJES2ZLH5cjs.isDexaDocument; exports.isValidCode = _chunkJES2ZLH5cjs.isValidCode; exports.isValidLoinc = _chunkJES2ZLH5cjs.isValidLoinc; exports.loincToCode = _chunkJES2ZLH5cjs.loincToCode; exports.methodVariantOf = _chunkJES2ZLH5cjs.methodVariantOf; exports.normalizeCode = _chunkJES2ZLH5cjs.normalizeCode; exports.toBiomarkerTests = _chunkJES2ZLH5cjs.toBiomarkerTests; exports.validateLoincNameMatch = _chunkJES2ZLH5cjs.validateLoincNameMatch;
+exports.BIOMARKER_DEFINITIONS = _chunkBDS6CM7Fcjs.BIOMARKER_DEFINITIONS; exports.CAC_INDICATOR_CODES = _chunkBDS6CM7Fcjs.CAC_INDICATOR_CODES; exports.DEXA_CATEGORIES = _chunkBDS6CM7Fcjs.DEXA_CATEGORIES; exports.DEXA_INDICATOR_CODES = _chunkBDS6CM7Fcjs.DEXA_INDICATOR_CODES; exports.codeToLoinc = _chunkBDS6CM7Fcjs.codeToLoinc; exports.filterVisibleBiomarkers = _chunkBDS6CM7Fcjs.filterVisibleBiomarkers; exports.findCodeByName = _chunkBDS6CM7Fcjs.findCodeByName; exports.generateCacFullReference = _chunkBDS6CM7Fcjs.generateCacFullReference; exports.generateDexaFullReference = _chunkBDS6CM7Fcjs.generateDexaFullReference; exports.generateFilteredLLMReference = _chunkBDS6CM7Fcjs.generateFilteredLLMReference; exports.generateLLMReference = _chunkBDS6CM7Fcjs.generateLLMReference; exports.getAllCodes = _chunkBDS6CM7Fcjs.getAllCodes; exports.getAllDefinitions = _chunkBDS6CM7Fcjs.getAllDefinitions; exports.getAllLoincCodes = _chunkBDS6CM7Fcjs.getAllLoincCodes; exports.getAllSearchPatterns = _chunkBDS6CM7Fcjs.getAllSearchPatterns; exports.getBiomarkersByCategory = _chunkBDS6CM7Fcjs.getBiomarkersByCategory; exports.getBiomarkersForCategories = _chunkBDS6CM7Fcjs.getBiomarkersForCategories; exports.getDefinitionByCode = _chunkBDS6CM7Fcjs.getDefinitionByCode; exports.getDefinitionByLoinc = _chunkBDS6CM7Fcjs.getDefinitionByLoinc; exports.getDefinitionsBySex = _chunkBDS6CM7Fcjs.getDefinitionsBySex; exports.getSexForCode = _chunkBDS6CM7Fcjs.getSexForCode; exports.getVisibleDefinitions = _chunkBDS6CM7Fcjs.getVisibleDefinitions; exports.isBiomarkerVisible = _chunkBDS6CM7Fcjs.isBiomarkerVisible; exports.isCacDocument = _chunkBDS6CM7Fcjs.isCacDocument; exports.isDexaDocument = _chunkBDS6CM7Fcjs.isDexaDocument; exports.isValidCode = _chunkBDS6CM7Fcjs.isValidCode; exports.isValidLoinc = _chunkBDS6CM7Fcjs.isValidLoinc; exports.loincToCode = _chunkBDS6CM7Fcjs.loincToCode; exports.methodVariantOf = _chunkBDS6CM7Fcjs.methodVariantOf; exports.normalizeCode = _chunkBDS6CM7Fcjs.normalizeCode; exports.toBiomarkerTests = _chunkBDS6CM7Fcjs.toBiomarkerTests; exports.validateLoincNameMatch = _chunkBDS6CM7Fcjs.validateLoincNameMatch;
 //# sourceMappingURL=biomarkers.cjs.map

package/dist/biomarkers.js

@@ -31,7 +31,7 @@ import {
   normalizeCode,
   toBiomarkerTests,
   validateLoincNameMatch
-} from "./chunk-KTV4H2QQ.js";
+} from "./chunk-YCJUGK6D.js";
 export {
   BIOMARKER_DEFINITIONS,
   CAC_INDICATOR_CODES,

package/dist/{chunk-WKTDMR5P.cjs → chunk-A2R65X4X.cjs}

@@ -4,15 +4,15 @@
 var _chunkOR67NJDZcjs = require('./chunk-OR67NJDZ.cjs');
 
 
-var _chunkH64L6SOVcjs = require('./chunk-H64L6SOV.cjs');
+var _chunkDE7NHXIRcjs = require('./chunk-DE7NHXIR.cjs');
 
 
 
-var _chunkAQTHAZLKcjs = require('./chunk-AQTHAZLK.cjs');
+var _chunkRWUFK5ANcjs = require('./chunk-RWUFK5AN.cjs');
 
 
 
-var _chunkJES2ZLH5cjs = require('./chunk-JES2ZLH5.cjs');
+var _chunkBDS6CM7Fcjs = require('./chunk-BDS6CM7F.cjs');
 
 // src/bundle-urls.ts
 var BUNDLE_BASE_URL = "https://precisa-saude.com.br/fhir";
@@ -63,16 +63,16 @@ var buildReferenceRanges = (observation, quantity) => {
   if (observation.referenceRanges && observation.referenceRanges.length > 0) {
     return observation.referenceRanges.flatMap((r) => toRanges(r.low, r.high, r.appliesTo));
   }
-  const meaning = observation.referenceKind && _chunkH64L6SOVcjs.referenceRangeMeaning.call(void 0, observation.referenceKind);
+  const meaning = observation.referenceKind && _chunkDE7NHXIRcjs.referenceRangeMeaning.call(void 0, observation.referenceKind);
   return toRanges(observation.referenceMin, observation.referenceMax).map(
     (range) => meaning ? { ...range, type: { coding: [meaning] } } : range
   );
 };
 function labObservationToFHIR(observation, patientId, laboratoryName) {
-  const methodLoinc = observation.methodLoinc && _chunkJES2ZLH5cjs.methodVariantOf.call(void 0, observation.biomarkerCode, observation.methodLoinc) ? observation.methodLoinc : void 0;
-  const loincCode = _nullishCoalesce(methodLoinc, () => ( _chunkJES2ZLH5cjs.codeToLoinc.call(void 0, observation.biomarkerCode)));
-  const sourceUnit = observation.unit || _chunkAQTHAZLKcjs.getDefaultUnit.call(void 0, observation.biomarkerCode) || observation.unit;
-  const ucumUnit = _chunkAQTHAZLKcjs.resolveUcum.call(void 0, sourceUnit, observation.biomarkerCode);
+  const methodLoinc = observation.methodLoinc && _chunkBDS6CM7Fcjs.methodVariantOf.call(void 0, observation.biomarkerCode, observation.methodLoinc) ? observation.methodLoinc : void 0;
+  const loincCode = _nullishCoalesce(methodLoinc, () => ( _chunkBDS6CM7Fcjs.codeToLoinc.call(void 0, observation.biomarkerCode)));
+  const sourceUnit = observation.unit || _chunkRWUFK5ANcjs.getDefaultUnit.call(void 0, observation.biomarkerCode) || observation.unit;
+  const ucumUnit = _chunkRWUFK5ANcjs.resolveUcum.call(void 0, sourceUnit, observation.biomarkerCode);
   const quantity = (value) => ({
     ...ucumUnit ? { code: ucumUnit, system: "http://unitsofmeasure.org" } : {},
     ...sourceUnit ? { unit: sourceUnit } : {},
@@ -273,4 +273,4 @@ function labResultToFHIRBundle(report, observations, userProfile) {
 
 
 exports.BUNDLE_BASE_URL = BUNDLE_BASE_URL; exports.entryFullUrl = entryFullUrl; exports.labObservationToFHIR = labObservationToFHIR; exports.labReportToFHIR = labReportToFHIR; exports.userProfileToFHIR = userProfileToFHIR; exports.labResultToFHIRBundle = labResultToFHIRBundle;
-//# sourceMappingURL=chunk-WKTDMR5P.cjs.map
+//# sourceMappingURL=chunk-A2R65X4X.cjs.map

package/dist/{chunk-WKTDMR5P.cjs.map → chunk-A2R65X4X.cjs.map}

@@ -1 +1 @@
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O defeito que\n * isto substitui nasceu de montar os dois lados em separado: o `fullUrl` dizia\n * `observation-demo-Hgb` enquanto o recurso tinha id `demo-Hgb`, e ninguém\n * percebeu porque nada obrigava os dois a concordarem.\n *\n * O parâmetro pede o mínimo que a URL consome, e não a união de recursos que\n * este pacote converte. Um Bundle pode carregar qualquer recurso do R4, e quem\n * acrescenta uma entrada de um tipo que não está nessa união (um `Specimen`,\n * por exemplo) precisa do mesmo endereço, senão monta o dele e as duas formas\n * divergem outra vez.\n */\nexport const entryFullUrl = (resource: Addressable<{ resourceType: string }>): string =>\n  `${BUNDLE_BASE_URL}/${resource.resourceType}/${resource.id}`;\n","/**\n * FHIR Converter\n *\n * Converts lab results to FHIR R4 DiagnosticReport and Observation resources.\n * See: https://hl7.org/fhir/diagnosticreport.html\n */\n\nimport { codeToLoinc, methodVariantOf } from './biomarkers';\nimport { type Addressable, entryFullUrl } from './bundle-urls';\nimport { BIOMARKER_CODE_SYSTEM, LOINC_SYSTEM } from './code-systems';\nimport type {\n  FHIRBundle,\n  FHIRDiagnosticReport,\n  FHIRObservation,\n  FHIRPatient,\n  FHIRQuantity,\n  FHIRReferenceRange,\n} from './fhir-types';\nimport { referenceRangeMeaning } from './reference-ranges';\nimport type { Flag, LabObservationData, LabReportData, UserProfileData } from './types';\nimport { getDefaultUnit, resolveUcum } from './units';\n\n// Re-export all types and functions\nexport * from './fhir-types';\n\n/**\n * Convert Flag to FHIR interpretation code\n */\nfunction interpretationCode(flag: Flag): string {\n  switch (flag) {\n    case 'H':\n      return 'H'; // High\n    case 'L':\n      return 'L'; // Low\n    default:\n      return 'N'; // Normal\n  }\n}\n\n/**\n * Convert Flag to FHIR interpretation display\n */\nfunction interpretationDisplay(flag: Flag): string {\n  switch (flag) {\n    case 'H':\n      return 'High';\n    case 'L':\n      return 'Low';\n    default:\n      return 'Normal';\n  }\n}\n\n/**\n * O `coding` do sexo, que vai **dentro** do CodeableConcept do `appliesTo`.\n *\n * O nome diz `CODING` e não `APPLIES_TO` de propósito: isto não é o valor do\n * campo, é uma entrada da lista de codificações dele. O embrulho acontece no\n * uso, em `{ coding: [SEX_CODING[sex]] }`.\n *\n * É o `AdministrativeGender`, e não o v3-ObservationInterpretation nem um\n * sistema nosso: um consumidor que já lê `Patient.gender` compara os dois sem\n * tabela de tradução no meio.\n */\nconst SEX_CODING = {\n  female: {\n    code: 'female',\n    display: 'Female',\n    system: 'http://hl7.org/fhir/administrative-gender',\n  },\n  male: { code: 'male', display: 'Male', system: 'http://hl7.org/fhir/administrative-gender' },\n} as const;\n\n/**\n * Monta as faixas de referência do `Observation`.\n *\n * Duas mudanças em relação ao que existia, e as duas são sobre não perder o que\n * o laudo imprimiu.\n *\n * **Um limite só já basta.** Antes a faixa só saía com os dois, e um laudo que\n * publica \"inferior a 190 mg/dL\" ou \"superior a 60 mL/min/1,73m²\" perdia o\n * campo inteiro. O R4 trata `low` e `high` como opcionais independentes e\n * documenta o caso de um lado só, e o importador deste mesmo pacote já lia\n * `low?.value` e `high?.value` com acesso opcional: a assimetria era só do\n * escritor. Ver PRE-430.\n *\n * **Mais de uma faixa, anotada.** Laudo com uma coluna de referência por sexo\n * passa a sair com as duas, cada uma com o seu `appliesTo`, em vez de o\n * pipeline escolher uma sem saber de quem é o exame. Ver PRE-424 e PRE-425.\n */\nconst buildReferenceRanges = (\n  observation: LabObservationData,\n  quantity: (value: number) => FHIRQuantity,\n): FHIRReferenceRange[] => {\n  // Devolve lista, e não uma faixa: o caso sem limite nenhum vira lista vazia\n  // em vez de `undefined`, e aí os dois caminhos abaixo se compõem com\n  // `flatMap` sem ninguém precisar filtrar nada depois.\n  const toRanges = (low?: number, high?: number, sex?: 'female' | 'male'): FHIRReferenceRange[] => {\n    if (low === undefined && high === undefined) return [];\n\n    return [\n      {\n        ...(sex === undefined ? {} : { appliesTo: [{ coding: [SEX_CODING[sex]] }] }),\n        ...(high === undefined ? {} : { high: quantity(high) }),\n        ...(low === undefined ? {} : { low: quantity(low) }),\n      },\n    ];\n  };\n\n  // A lista anotada tem precedência: quando ela existe, o par simples é o\n  // resumo de uma das colunas e repeti-lo publicaria a mesma faixa duas vezes,\n  // uma delas sem dizer a quem se aplica.\n  //\n  // Lista vazia cai no par simples, igual a ausente, e isso é escolha: as duas\n  // dizem \"não tenho faixa anotada\", e tratá-las diferente faria um `[]` vindo\n  // de um `.filter()` apagar em silêncio a faixa que o chamador também mandou\n  // em `referenceMin` e `referenceMax`.\n  if (observation.referenceRanges && observation.referenceRanges.length > 0) {\n    return observation.referenceRanges.flatMap((r) => toRanges(r.low, r.high, r.appliesTo));\n  }\n\n  const meaning = observation.referenceKind && referenceRangeMeaning(observation.referenceKind);\n  return toRanges(observation.referenceMin, observation.referenceMax).map((range) =>\n    meaning ? { ...range, type: { coding: [meaning] } } : range,\n  );\n};\n\n/**\n * Convert generic lab observation to FHIR Observation\n */\nexport function labObservationToFHIR(\n  observation: LabObservationData,\n  patientId: string,\n  laboratoryName?: string,\n): Addressable<FHIRObservation> {\n  // O código por método só sai quando é variante declarada do biomarcador. Um\n  // `methodLoinc` qualquer viraria afirmação sob `http://loinc.org` que o\n  // catálogo não conferiu.\n  const methodLoinc =\n    observation.methodLoinc && methodVariantOf(observation.biomarkerCode, observation.methodLoinc)\n      ? observation.methodLoinc\n      : undefined;\n  const loincCode = methodLoinc ?? codeToLoinc(observation.biomarkerCode);\n  // Use default unit if source unit is empty\n  const sourceUnit =\n    observation.unit || getDefaultUnit(observation.biomarkerCode) || observation.unit;\n  // `system` + `code` só saem quando a unidade resolve em UCUM. Unidade que o\n  // pacote não sabe traduzir fica só em `unit`, como texto: afirmar\n  // `http://unitsofmeasure.org` sobre `x10^3/mm3` era publicar um código\n  // falso, e quem consome o Bundle confiando no system trataria aquilo como\n  // UCUM de verdade.\n  const ucumUnit = resolveUcum(sourceUnit, observation.biomarkerCode);\n  const quantity = (value: number): FHIRQuantity => ({\n    ...(ucumUnit ? { code: ucumUnit, system: 'http://unitsofmeasure.org' } : {}),\n    ...(sourceUnit ? { unit: sourceUnit } : {}),\n    value,\n  });\n  const isQualitative = observation.isQualitative || typeof observation.value === 'string';\n\n  // Base observation structure\n  const fhirObs: Addressable<FHIRObservation> = {\n    category: [\n      {\n        coding: [\n          {\n            code: 'laboratory',\n            display: 'Laboratory',\n            system: 'http://terminology.hl7.org/CodeSystem/observation-category',\n          },\n        ],\n      },\n    ],\n    code: {\n      // Sem LOINC, o coding LOINC simplesmente não sai. Antes ia `99999-9`,\n      // que não é código LOINC nenhum: publicava sob `http://loinc.org` uma\n      // afirmação falsa, e quem consumisse o bundle confiando no system\n      // trataria aquilo como código de verdade. Composição corporal, densidade\n      // óssea e escore de cálcio não têm LOINC, e o certo é a lacuna explícita.\n      coding: [\n        ...(loincCode\n          ? [\n              {\n                code: loincCode,\n                display: observation.biomarkerName,\n                system: LOINC_SYSTEM,\n              },\n            ]\n          : []),\n        {\n          code: observation.biomarkerCode,\n          display: observation.biomarkerName,\n          system: BIOMARKER_CODE_SYSTEM,\n        },\n      ],\n      text: observation.biomarkerName,\n    },\n    effectiveDateTime: observation.collectionDate,\n    id: `${observation.reportId}-${observation.biomarkerCode}`,\n    interpretation: [\n      {\n        coding: [\n          {\n            code: interpretationCode(observation.flag),\n            display: interpretationDisplay(observation.flag),\n            system: 'http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation',\n          },\n        ],\n      },\n    ],\n    performer: laboratoryName ? [{ display: laboratoryName }] : undefined,\n    resourceType: 'Observation',\n    status: 'final',\n    subject: {\n      reference: `Patient/${patientId}`,\n    },\n  };\n\n  // Add value based on type (qualitative = string, quantitative = number)\n  if (isQualitative) {\n    fhirObs.valueString = String(observation.value);\n  } else {\n    fhirObs.valueQuantity = quantity(observation.value as number);\n\n    // Reference range only applies to quantitative values\n    const referenceRange = buildReferenceRanges(observation, quantity);\n    if (referenceRange.length > 0) fhirObs.referenceRange = referenceRange;\n  }\n\n  return fhirObs;\n}\n\n/**\n * Convert generic lab report to FHIR DiagnosticReport\n */\nexport function labReportToFHIR(\n  report: LabReportData,\n  patientId: string,\n  observationIds: string[],\n): Addressable<FHIRDiagnosticReport> {\n  // Map processing status to FHIR status\n  let status: FHIRDiagnosticReport['status'];\n  switch (report.processingStatus) {\n    case 'complete':\n      status = 'final';\n      break;\n    case 'partial':\n      status = 'partial';\n      break;\n    case 'pending_review':\n      status = 'preliminary';\n      break;\n    default:\n      status = 'final';\n  }\n\n  return {\n    category: [\n      {\n        coding: [\n          {\n            code: 'LAB',\n            display: 'Laboratory',\n            system: 'http://terminology.hl7.org/CodeSystem/v2-0074',\n          },\n        ],\n      },\n    ],\n    code: {\n      coding: [\n        {\n          code: '11502-2', // Laboratory report\n          display: 'Laboratory report',\n          system: 'http://loinc.org',\n        },\n      ],\n      text: 'Laboratory Results',\n    },\n    conclusion:\n      report.overallStatus === 'NORMAL'\n        ? 'All results within normal limits'\n        : 'One or more abnormal results detected',\n    conclusionCode:\n      report.overallStatus === 'ANORMAL'\n        ? [\n            {\n              coding: [\n                {\n                  code: 'A',\n                  display: 'Abnormal',\n                  system: 'http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation',\n                },\n              ],\n            },\n          ]\n        : undefined,\n    effectiveDateTime: report.collectionDate,\n    id: report.reportId,\n    issued: report.createdAt,\n    performer: report.laboratoryName ? [{ display: report.laboratoryName }] : undefined,\n    resourceType: 'DiagnosticReport',\n    result: observationIds.map((id) => ({ reference: `Observation/${id}` })),\n    status,\n    subject: {\n      reference: `Patient/${patientId}`,\n    },\n  };\n}\n\n/**\n * Convert user profile to FHIR Patient\n * NOTE: CPF is intentionally excluded for privacy (LGPD compliance)\n */\nexport function userProfileToFHIR(profile: UserProfileData): Addressable<FHIRPatient> {\n  const nameParts = profile.name.split(' ');\n  const given = nameParts.slice(0, -1);\n  const family = nameParts[nameParts.length - 1] || '';\n\n  return {\n    address: profile.address\n      ? [\n          {\n            city: profile.address.city,\n            country: profile.address.country || 'BR',\n            line: [\n              profile.address.street && profile.address.number\n                ? `${profile.address.street}, ${profile.address.number}`\n                : profile.address.street,\n              profile.address.complement,\n            ].filter(Boolean) as string[],\n            postalCode: profile.address.postalCode,\n            state: profile.address.state,\n          },\n        ]\n      : undefined,\n    birthDate: profile.birthDate,\n    gender: profile.gender,\n    id: profile.userId,\n    name: [\n      {\n        family,\n        given: given.length > 0 ? given : undefined,\n        text: profile.name,\n      },\n    ],\n    resourceType: 'Patient',\n    telecom:\n      [\n        ...(profile.email ? [{ system: 'email' as const, value: profile.email }] : []),\n        ...(profile.phone ? [{ system: 'phone' as const, value: profile.phone }] : []),\n      ].length > 0\n        ? [\n            ...(profile.email ? [{ system: 'email' as const, value: profile.email }] : []),\n            ...(profile.phone ? [{ system: 'phone' as const, value: profile.phone }] : []),\n          ]\n        : undefined,\n  };\n}\n\n/**\n * Convert complete lab result to FHIR Bundle\n * This is the main function for exporting lab results to FHIR R4 format\n */\nexport function labResultToFHIRBundle(\n  report: LabReportData,\n  observations: LabObservationData[],\n  userProfile: UserProfileData,\n): FHIRBundle {\n  const patientId = userProfile.userId;\n\n  // Convert observations\n  const fhirObservations = observations.map((obs) => {\n    const resource = labObservationToFHIR(\n      { ...obs, collectionDate: report.collectionDate },\n      patientId,\n      report.laboratoryName,\n    );\n\n    return { fullUrl: entryFullUrl(resource), resource };\n  });\n\n  // Os ids vêm dos recursos já montados, e não de uma segunda montagem da mesma\n  // regra. O `DiagnosticReport.result` aponta para eles, e era aqui que a\n  // referência se separava do recurso.\n  const observationIds = fhirObservations.map((entry) => entry.resource.id);\n\n  // Convert report\n  const diagnosticReport = labReportToFHIR(report, patientId, observationIds);\n\n  // Convert patient\n  const fhirPatient = userProfileToFHIR(userProfile);\n\n  return {\n    entry: [\n      { fullUrl: entryFullUrl(fhirPatient), resource: fhirPatient },\n      { fullUrl: entryFullUrl(diagnosticReport), resource: diagnosticReport },\n      ...fhirObservations,\n    ],\n    resourceType: 'Bundle',\n    type: 'collection',\n  };\n}\n"]}
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Um Bundle com `subject.reference` valendo\n * `Patient/abc` só resolve se alguma entrada tiver `fullUrl` terminando em\n * `/Patient/abc`: a referência relativa é lida contra a base do `fullUrl` da\n * entrada, que é como os exemplos da própria HL7 montam Bundle de coleção.\n *\n * Antes o `fullUrl` era `urn:uuid:observation-<laudo>-<código>`, que erra duas\n * vezes. `urn:uuid:` exige a sintaxe de UUID e aquilo não era um UUID, e num\n * Bundle de entradas `urn:uuid:` a referência precisa repetir a URN inteira,\n * então nenhuma das relativas resolvia. Um laudo de 22 marcadores saía com 24\n * erros de URN e 22 referências perdidas.\n */\n/**\n * Recurso que já tem id, e por isso pode ser endereçado numa entrada.\n *\n * No FHIR o `id` é opcional, porque um recurso pode viajar sem identidade\n * própria. Numa entrada de Bundle ele não pode: sem id não há `fullUrl`, e sem\n * `fullUrl` nenhuma referência chega ao recurso. Os conversores daqui sempre\n * atribuem um, e o tipo passa a dizer isso em vez de deixar `undefined` chegar\n * até a montagem da URL.\n */\nexport type Addressable<T> = T & { id: string };\n\n/**\n * Base dos `fullUrl`.\n *\n * Não precisa responder a uma requisição: no FHIR o `fullUrl` é identidade, não\n * endereço de download. Fica sob um domínio nosso para não colidir com a\n * identidade de recurso de outra instituição, que é o risco real de usar\n * `example.org` em dado que sai da máquina.\n */\nexport const BUNDLE_BASE_URL = 'https://precisa-saude.com.br/fhir';\n\n/**\n * Monta o `fullUrl` a partir do próprio recurso.\n *\n * Recebe o recurso em vez do tipo e do id soltos de propósito. O defeito que\n * isto substitui nasceu de montar os dois lados em separado: o `fullUrl` dizia\n * `observation-demo-Hgb` enquanto o recurso tinha id `demo-Hgb`, e ninguém\n * percebeu porque nada obrigava os dois a concordarem.\n *\n * O parâmetro pede o mínimo que a URL consome, e não a união de recursos que\n * este pacote converte. Um Bundle pode carregar qualquer recurso do R4, e quem\n * acrescenta uma entrada de um tipo que não está nessa união (um `Specimen`,\n * por exemplo) precisa do mesmo endereço, senão monta o dele e as duas formas\n * divergem outra vez.\n */\nexport const entryFullUrl = (resource: Addressable<{ resourceType: string }>): string =>\n  `${BUNDLE_BASE_URL}/${resource.resourceType}/${resource.id}`;\n","/**\n * FHIR Converter\n *\n * Converts lab results to FHIR R4 DiagnosticReport and Observation resources.\n * See: https://hl7.org/fhir/diagnosticreport.html\n */\n\nimport { codeToLoinc, methodVariantOf } from './biomarkers';\nimport { type Addressable, entryFullUrl } from './bundle-urls';\nimport { BIOMARKER_CODE_SYSTEM, LOINC_SYSTEM } from './code-systems';\nimport type {\n  FHIRBundle,\n  FHIRDiagnosticReport,\n  FHIRObservation,\n  FHIRPatient,\n  FHIRQuantity,\n  FHIRReferenceRange,\n} from './fhir-types';\nimport { referenceRangeMeaning } from './reference-ranges';\nimport type { Flag, LabObservationData, LabReportData, UserProfileData } from './types';\nimport { getDefaultUnit, resolveUcum } from './units';\n\n// Re-export all types and functions\nexport * from './fhir-types';\n\n/**\n * Convert Flag to FHIR interpretation code\n */\nfunction interpretationCode(flag: Flag): string {\n  switch (flag) {\n    case 'H':\n      return 'H'; // High\n    case 'L':\n      return 'L'; // Low\n    default:\n      return 'N'; // Normal\n  }\n}\n\n/**\n * Convert Flag to FHIR interpretation display\n */\nfunction interpretationDisplay(flag: Flag): string {\n  switch (flag) {\n    case 'H':\n      return 'High';\n    case 'L':\n      return 'Low';\n    default:\n      return 'Normal';\n  }\n}\n\n/**\n * O `coding` do sexo, que vai **dentro** do CodeableConcept do `appliesTo`.\n *\n * O nome diz `CODING` e não `APPLIES_TO` de propósito: isto não é o valor do\n * campo, é uma entrada da lista de codificações dele. O embrulho acontece no\n * uso, em `{ coding: [SEX_CODING[sex]] }`.\n *\n * É o `AdministrativeGender`, e não o v3-ObservationInterpretation nem um\n * sistema nosso: um consumidor que já lê `Patient.gender` compara os dois sem\n * tabela de tradução no meio.\n */\nconst SEX_CODING = {\n  female: {\n    code: 'female',\n    display: 'Female',\n    system: 'http://hl7.org/fhir/administrative-gender',\n  },\n  male: { code: 'male', display: 'Male', system: 'http://hl7.org/fhir/administrative-gender' },\n} as const;\n\n/**\n * Monta as faixas de referência do `Observation`.\n *\n * Duas mudanças em relação ao que existia, e as duas são sobre não perder o que\n * o laudo imprimiu.\n *\n * **Um limite só já basta.** Antes a faixa só saía com os dois, e um laudo que\n * publica \"inferior a 190 mg/dL\" ou \"superior a 60 mL/min/1,73m²\" perdia o\n * campo inteiro. O R4 trata `low` e `high` como opcionais independentes e\n * documenta o caso de um lado só, e o importador deste mesmo pacote já lia\n * `low?.value` e `high?.value` com acesso opcional: a assimetria era só do\n * escritor. Ver PRE-430.\n *\n * **Mais de uma faixa, anotada.** Laudo com uma coluna de referência por sexo\n * passa a sair com as duas, cada uma com o seu `appliesTo`, em vez de o\n * pipeline escolher uma sem saber de quem é o exame. Ver PRE-424 e PRE-425.\n */\nconst buildReferenceRanges = (\n  observation: LabObservationData,\n  quantity: (value: number) => FHIRQuantity,\n): FHIRReferenceRange[] => {\n  // Devolve lista, e não uma faixa: o caso sem limite nenhum vira lista vazia\n  // em vez de `undefined`, e aí os dois caminhos abaixo se compõem com\n  // `flatMap` sem ninguém precisar filtrar nada depois.\n  const toRanges = (low?: number, high?: number, sex?: 'female' | 'male'): FHIRReferenceRange[] => {\n    if (low === undefined && high === undefined) return [];\n\n    return [\n      {\n        ...(sex === undefined ? {} : { appliesTo: [{ coding: [SEX_CODING[sex]] }] }),\n        ...(high === undefined ? {} : { high: quantity(high) }),\n        ...(low === undefined ? {} : { low: quantity(low) }),\n      },\n    ];\n  };\n\n  // A lista anotada tem precedência: quando ela existe, o par simples é o\n  // resumo de uma das colunas e repeti-lo publicaria a mesma faixa duas vezes,\n  // uma delas sem dizer a quem se aplica.\n  //\n  // Lista vazia cai no par simples, igual a ausente, e isso é escolha: as duas\n  // dizem \"não tenho faixa anotada\", e tratá-las diferente faria um `[]` vindo\n  // de um `.filter()` apagar em silêncio a faixa que o chamador também mandou\n  // em `referenceMin` e `referenceMax`.\n  if (observation.referenceRanges && observation.referenceRanges.length > 0) {\n    return observation.referenceRanges.flatMap((r) => toRanges(r.low, r.high, r.appliesTo));\n  }\n\n  const meaning = observation.referenceKind && referenceRangeMeaning(observation.referenceKind);\n  return toRanges(observation.referenceMin, observation.referenceMax).map((range) =>\n    meaning ? { ...range, type: { coding: [meaning] } } : range,\n  );\n};\n\n/**\n * Convert generic lab observation to FHIR Observation\n */\nexport function labObservationToFHIR(\n  observation: LabObservationData,\n  patientId: string,\n  laboratoryName?: string,\n): Addressable<FHIRObservation> {\n  // O código por método só sai quando é variante declarada do biomarcador. Um\n  // `methodLoinc` qualquer viraria afirmação sob `http://loinc.org` que o\n  // catálogo não conferiu.\n  const methodLoinc =\n    observation.methodLoinc && methodVariantOf(observation.biomarkerCode, observation.methodLoinc)\n      ? observation.methodLoinc\n      : undefined;\n  const loincCode = methodLoinc ?? codeToLoinc(observation.biomarkerCode);\n  // Use default unit if source unit is empty\n  const sourceUnit =\n    observation.unit || getDefaultUnit(observation.biomarkerCode) || observation.unit;\n  // `system` + `code` só saem quando a unidade resolve em UCUM. Unidade que o\n  // pacote não sabe traduzir fica só em `unit`, como texto: afirmar\n  // `http://unitsofmeasure.org` sobre `x10^3/mm3` era publicar um código\n  // falso, e quem consome o Bundle confiando no system trataria aquilo como\n  // UCUM de verdade.\n  const ucumUnit = resolveUcum(sourceUnit, observation.biomarkerCode);\n  const quantity = (value: number): FHIRQuantity => ({\n    ...(ucumUnit ? { code: ucumUnit, system: 'http://unitsofmeasure.org' } : {}),\n    ...(sourceUnit ? { unit: sourceUnit } : {}),\n    value,\n  });\n  const isQualitative = observation.isQualitative || typeof observation.value === 'string';\n\n  // Base observation structure\n  const fhirObs: Addressable<FHIRObservation> = {\n    category: [\n      {\n        coding: [\n          {\n            code: 'laboratory',\n            display: 'Laboratory',\n            system: 'http://terminology.hl7.org/CodeSystem/observation-category',\n          },\n        ],\n      },\n    ],\n    code: {\n      // Sem LOINC, o coding LOINC simplesmente não sai. Antes ia `99999-9`,\n      // que não é código LOINC nenhum: publicava sob `http://loinc.org` uma\n      // afirmação falsa, e quem consumisse o bundle confiando no system\n      // trataria aquilo como código de verdade. Composição corporal, densidade\n      // óssea e escore de cálcio não têm LOINC, e o certo é a lacuna explícita.\n      coding: [\n        ...(loincCode\n          ? [\n              {\n                code: loincCode,\n                display: observation.biomarkerName,\n                system: LOINC_SYSTEM,\n              },\n            ]\n          : []),\n        {\n          code: observation.biomarkerCode,\n          display: observation.biomarkerName,\n          system: BIOMARKER_CODE_SYSTEM,\n        },\n      ],\n      text: observation.biomarkerName,\n    },\n    effectiveDateTime: observation.collectionDate,\n    id: `${observation.reportId}-${observation.biomarkerCode}`,\n    interpretation: [\n      {\n        coding: [\n          {\n            code: interpretationCode(observation.flag),\n            display: interpretationDisplay(observation.flag),\n            system: 'http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation',\n          },\n        ],\n      },\n    ],\n    performer: laboratoryName ? [{ display: laboratoryName }] : undefined,\n    resourceType: 'Observation',\n    status: 'final',\n    subject: {\n      reference: `Patient/${patientId}`,\n    },\n  };\n\n  // Add value based on type (qualitative = string, quantitative = number)\n  if (isQualitative) {\n    fhirObs.valueString = String(observation.value);\n  } else {\n    fhirObs.valueQuantity = quantity(observation.value as number);\n\n    // Reference range only applies to quantitative values\n    const referenceRange = buildReferenceRanges(observation, quantity);\n    if (referenceRange.length > 0) fhirObs.referenceRange = referenceRange;\n  }\n\n  return fhirObs;\n}\n\n/**\n * Convert generic lab report to FHIR DiagnosticReport\n */\nexport function labReportToFHIR(\n  report: LabReportData,\n  patientId: string,\n  observationIds: string[],\n): Addressable<FHIRDiagnosticReport> {\n  // Map processing status to FHIR status\n  let status: FHIRDiagnosticReport['status'];\n  switch (report.processingStatus) {\n    case 'complete':\n      status = 'final';\n      break;\n    case 'partial':\n      status = 'partial';\n      break;\n    case 'pending_review':\n      status = 'preliminary';\n      break;\n    default:\n      status = 'final';\n  }\n\n  return {\n    category: [\n      {\n        coding: [\n          {\n            code: 'LAB',\n            display: 'Laboratory',\n            system: 'http://terminology.hl7.org/CodeSystem/v2-0074',\n          },\n        ],\n      },\n    ],\n    code: {\n      coding: [\n        {\n          code: '11502-2', // Laboratory report\n          display: 'Laboratory report',\n          system: 'http://loinc.org',\n        },\n      ],\n      text: 'Laboratory Results',\n    },\n    conclusion:\n      report.overallStatus === 'NORMAL'\n        ? 'All results within normal limits'\n        : 'One or more abnormal results detected',\n    conclusionCode:\n      report.overallStatus === 'ANORMAL'\n        ? [\n            {\n              coding: [\n                {\n                  code: 'A',\n                  display: 'Abnormal',\n                  system: 'http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation',\n                },\n              ],\n            },\n          ]\n        : undefined,\n    effectiveDateTime: report.collectionDate,\n    id: report.reportId,\n    issued: report.createdAt,\n    performer: report.laboratoryName ? [{ display: report.laboratoryName }] : undefined,\n    resourceType: 'DiagnosticReport',\n    result: observationIds.map((id) => ({ reference: `Observation/${id}` })),\n    status,\n    subject: {\n      reference: `Patient/${patientId}`,\n    },\n  };\n}\n\n/**\n * Convert user profile to FHIR Patient\n * NOTE: CPF is intentionally excluded for privacy (LGPD compliance)\n */\nexport function userProfileToFHIR(profile: UserProfileData): Addressable<FHIRPatient> {\n  const nameParts = profile.name.split(' ');\n  const given = nameParts.slice(0, -1);\n  const family = nameParts[nameParts.length - 1] || '';\n\n  return {\n    address: profile.address\n      ? [\n          {\n            city: profile.address.city,\n            country: profile.address.country || 'BR',\n            line: [\n              profile.address.street && profile.address.number\n                ? `${profile.address.street}, ${profile.address.number}`\n                : profile.address.street,\n              profile.address.complement,\n            ].filter(Boolean) as string[],\n            postalCode: profile.address.postalCode,\n            state: profile.address.state,\n          },\n        ]\n      : undefined,\n    birthDate: profile.birthDate,\n    gender: profile.gender,\n    id: profile.userId,\n    name: [\n      {\n        family,\n        given: given.length > 0 ? given : undefined,\n        text: profile.name,\n      },\n    ],\n    resourceType: 'Patient',\n    telecom:\n      [\n        ...(profile.email ? [{ system: 'email' as const, value: profile.email }] : []),\n        ...(profile.phone ? [{ system: 'phone' as const, value: profile.phone }] : []),\n      ].length > 0\n        ? [\n            ...(profile.email ? [{ system: 'email' as const, value: profile.email }] : []),\n            ...(profile.phone ? [{ system: 'phone' as const, value: profile.phone }] : []),\n          ]\n        : undefined,\n  };\n}\n\n/**\n * Convert complete lab result to FHIR Bundle\n * This is the main function for exporting lab results to FHIR R4 format\n */\nexport function labResultToFHIRBundle(\n  report: LabReportData,\n  observations: LabObservationData[],\n  userProfile: UserProfileData,\n): FHIRBundle {\n  const patientId = userProfile.userId;\n\n  // Convert observations\n  const fhirObservations = observations.map((obs) => {\n    const resource = labObservationToFHIR(\n      { ...obs, collectionDate: report.collectionDate },\n      patientId,\n      report.laboratoryName,\n    );\n\n    return { fullUrl: entryFullUrl(resource), resource };\n  });\n\n  // Os ids vêm dos recursos já montados, e não de uma segunda montagem da mesma\n  // regra. O `DiagnosticReport.result` aponta para eles, e era aqui que a\n  // referência se separava do recurso.\n  const observationIds = fhirObservations.map((entry) => entry.resource.id);\n\n  // Convert report\n  const diagnosticReport = labReportToFHIR(report, patientId, observationIds);\n\n  // Convert patient\n  const fhirPatient = userProfileToFHIR(userProfile);\n\n  return {\n    entry: [\n      { fullUrl: entryFullUrl(fhirPatient), resource: fhirPatient },\n      { fullUrl: entryFullUrl(diagnosticReport), resource: diagnosticReport },\n      ...fhirObservations,\n    ],\n    resourceType: 'Bundle',\n    type: 'collection',\n  };\n}\n"]}

package/dist/{chunk-F7CC4SV5.cjs → chunk-AJUDODBT.cjs}

@@ -1,6 +1,6 @@
 "use strict";Object.defineProperty(exports, "__esModule", {value: true}); function _nullishCoalesce(lhs, rhsFn) { if (lhs != null) { return lhs; } else { return rhsFn(); } } function _optionalChain(ops) { let lastAccessLHS = undefined; let value = ops[0]; let i = 1; while (i < ops.length) { const op = ops[i]; const fn = ops[i + 1]; i += 2; if ((op === 'optionalAccess' || op === 'optionalCall') && value == null) { return undefined; } if (op === 'access' || op === 'optionalAccess') { lastAccessLHS = value; value = fn(value); } else if (op === 'call' || op === 'optionalCall') { value = fn((...args) => value.call(lastAccessLHS, ...args)); lastAccessLHS = undefined; } } return value; }
 
-var _chunkRPGJK7ZMcjs = require('./chunk-RPGJK7ZM.cjs');
+var _chunkLSC7NHFEcjs = require('./chunk-LSC7NHFE.cjs');
 
 
 
@@ -12,7 +12,7 @@ var _chunkOR67NJDZcjs = require('./chunk-OR67NJDZ.cjs');
 
 
 
-var _chunkJES2ZLH5cjs = require('./chunk-JES2ZLH5.cjs');
+var _chunkBDS6CM7Fcjs = require('./chunk-BDS6CM7F.cjs');
 
 // src/importer.ts
 var MAX_OBSERVATIONS = 5e3;
@@ -34,11 +34,11 @@ function resolveBiomarkerCode(observation) {
   } else {
     reason = "No code found in observation coding";
   }
-  const fromLoinc = loincCode ? _chunkJES2ZLH5cjs.loincToCode.call(void 0, loincCode) : void 0;
+  const fromLoinc = loincCode ? _chunkBDS6CM7Fcjs.loincToCode.call(void 0, loincCode) : void 0;
   if (fromLoinc) return { internalCode: fromLoinc, loincCode, reason };
-  if (declaredCode && _chunkJES2ZLH5cjs.isValidCode.call(void 0, declaredCode)) {
-    const canonical = _chunkJES2ZLH5cjs.normalizeCode.call(void 0, declaredCode);
-    return { internalCode: canonical, loincCode: _chunkJES2ZLH5cjs.codeToLoinc.call(void 0, canonical), reason };
+  if (declaredCode && _chunkBDS6CM7Fcjs.isValidCode.call(void 0, declaredCode)) {
+    const canonical = _chunkBDS6CM7Fcjs.normalizeCode.call(void 0, declaredCode);
+    return { internalCode: canonical, loincCode: _chunkBDS6CM7Fcjs.codeToLoinc.call(void 0, canonical), reason };
   }
   return { loincCode, reason };
 }
@@ -75,7 +75,7 @@ function mapFHIRObservationToInternal(observation, index) {
       skipped: { index, loincCode, reason, resourceType: "Observation" }
     };
   }
-  const definition = _chunkJES2ZLH5cjs.getDefinitionByCode.call(void 0, internalCode);
+  const definition = _chunkBDS6CM7Fcjs.getDefinitionByCode.call(void 0, internalCode);
   let value;
   let unit = "";
   let isQualitative = false;
@@ -125,7 +125,7 @@ function mapFHIRObservationToInternal(observation, index) {
     flag: extractFlag(observation),
     isQualitative,
     loincCode,
-    ...loincCode && _chunkJES2ZLH5cjs.methodVariantOf.call(void 0, internalCode, loincCode) && { methodLoinc: loincCode },
+    ...loincCode && _chunkBDS6CM7Fcjs.methodVariantOf.call(void 0, internalCode, loincCode) && { methodLoinc: loincCode },
     ...referenceKind && { referenceKind },
     referenceMax,
     referenceMin,
@@ -135,7 +135,7 @@ function mapFHIRObservationToInternal(observation, index) {
   return { observation: imported };
 }
 function processImportBundle(data) {
-  const validationErrors = _chunkRPGJK7ZMcjs.validateFHIRImportBundle.call(void 0, data);
+  const validationErrors = _chunkLSC7NHFEcjs.validateFHIRImportBundle.call(void 0, data);
   if (validationErrors.length > 0) {
     return {
       errors: validationErrors,
@@ -171,4 +171,4 @@ function processImportBundle(data) {
 
 
 exports.MAX_OBSERVATIONS = MAX_OBSERVATIONS; exports.MAX_FILE_SIZE = MAX_FILE_SIZE; exports.extractObservationsFromBundle = extractObservationsFromBundle; exports.mapFHIRObservationToInternal = mapFHIRObservationToInternal; exports.processImportBundle = processImportBundle;
-//# sourceMappingURL=chunk-F7CC4SV5.cjs.map
+//# sourceMappingURL=chunk-AJUDODBT.cjs.map

package/dist/{chunk-F7CC4SV5.cjs.map → chunk-AJUDODBT.cjs.map}

@@ -1 +1 @@
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Nesse tamanho, 5000 Observations dão 6,0MB\n * compactos ou 13,1MB indentados, e por isso o teto de arquivo é 15MB: cobre\n * as duas formas com folga.\n *\n * Na densidade desse mesmo histórico (16 Observations por laudo), 5000\n * equivalem a cerca de 300 laudos.\n */\nconst MAX_OBSERVATIONS = 5000;\nconst MAX_FILE_SIZE = 15 * 1024 * 1024; // 15MB\n\n/**\n * Resolve o código interno do biomarcador a partir do `code.coding`.\n *\n * LOINC primeiro, que é o vocabulário que arquivos de terceiros usam. Quando\n * não resolve, cai para o coding de códigos internos, presente nos arquivos\n * exportados pela própria plataforma.\n *\n * O fallback cobre dois casos: biomarcadores sem LOINC publicado (composição\n * corporal, densidade óssea, escore de cálcio) e arquivos antigos, exportados\n * quando esses biomarcadores saíam com o placeholder `99999-9`, que não\n * resolve para nada.\n */\nfunction resolveBiomarkerCode(observation: FHIRObservation): {\n  internalCode?: string;\n  loincCode?: string;\n  reason: string;\n} {\n  const coding = observation.code?.coding ?? [];\n  const loincCode = coding.find((c) => c.system === LOINC_SYSTEM)?.code;\n  const declaredCode = coding.find((c) => c.system === BIOMARKER_CODE_SYSTEM)?.code;\n\n  const seenCodes = [\n    ...(loincCode ? [`LOINC ${loincCode}`] : []),\n    ...(declaredCode ? [`biomarker code ${declaredCode}`] : []),\n  ];\n\n  // Três motivos distintos de descarte, que antes se confundiam num só. Sem\n  // essa separação, um arquivo em SNOMED relatava \"nenhum código encontrado\",\n  // sugerindo `coding` vazio quando na verdade o código existia e estava num\n  // system que não tratamos. Para importação de terceiros, é a diferença entre\n  // um diagnóstico acionável e um enigma.\n  let reason: string;\n  if (seenCodes.length > 0) {\n    reason = `Unknown code: ${seenCodes.join(', ')}`;\n  } else if (coding.length > 0) {\n    const systems = [...new Set(coding.map((c) => c.system ?? '(sem system)'))];\n    reason = `No code in a supported system (found: ${systems.join(', ')})`;\n  } else {\n    reason = 'No code found in observation coding';\n  }\n\n  const fromLoinc = loincCode ? loincToCode(loincCode) : undefined;\n  if (fromLoinc) return { internalCode: fromLoinc, loincCode, reason };\n\n  if (declaredCode && isValidCode(declaredCode)) {\n    // `isValidCode` aceita alias, mas alias não serve como código armazenado:\n    // 49 definições têm um, e tanto `codeToLoinc` quanto as faixas de\n    // referência são indexadas só pelo canônico. Sem normalizar, `VLDL_Cholesterol`\n    // entraria no lugar de `VLDL` e perderia o LOINC 13458-5 que ele tem.\n    // Importar um Bundle é fronteira de dados, que é onde `normalizeCode` deve\n    // ser aplicado.\n    const canonical = normalizeCode(declaredCode);\n\n    // `codeToLoinc` devolve undefined para quem não tem LOINC, que é o caso\n    // esperado aqui. O campo fica de fora em vez de receber um valor inventado.\n    return { internalCode: canonical, loincCode: codeToLoinc(canonical), reason };\n  }\n\n  return { loincCode, reason };\n}\n\n/**\n * Extract interpretation flag from Observation\n */\nfunction extractFlag(observation: FHIRObservation): 'H' | 'L' | '' {\n  const code = observation.interpretation?.[0]?.coding?.[0]?.code;\n  if (code === 'H' || code === 'HH') return 'H';\n  if (code === 'L' || code === 'LL') return 'L';\n  return '';\n}\n\n/**\n * Extract Observation resources from a FHIR Bundle\n */\nexport function extractObservationsFromBundle(bundle: FHIRBundle): {\n  observations: FHIRObservation[];\n  skipped: SkippedEntry[];\n} {\n  const observations: FHIRObservation[] = [];\n  const skipped: SkippedEntry[] = [];\n\n  for (let i = 0; i < bundle.entry.length; i++) {\n    const entry = bundle.entry[i]!;\n    if (!entry.resource) {\n      skipped.push({ index: i, reason: 'Entry has no resource' });\n      continue;\n    }\n\n    if (entry.resource.resourceType !== 'Observation') {\n      // Non-observation resources are silently skipped (Patient, DiagnosticReport, etc.)\n      continue;\n    }\n\n    if (observations.length >= MAX_OBSERVATIONS) {\n      skipped.push({ index: i, reason: `Maximum of ${MAX_OBSERVATIONS} observations exceeded` });\n      continue;\n    }\n\n    observations.push(entry.resource as FHIRObservation);\n  }\n\n  return { observations, skipped };\n}\n\n/**\n * Map a FHIR Observation to internal format using LOINC→biomarker code lookup\n */\nexport function mapFHIRObservationToInternal(\n  observation: FHIRObservation,\n  index: number,\n): { observation: ImportedObservation } | { skipped: SkippedEntry } {\n  const { internalCode, loincCode, reason } = resolveBiomarkerCode(observation);\n\n  if (!internalCode) {\n    return {\n      skipped: { index, loincCode, reason, resourceType: 'Observation' },\n    };\n  }\n\n  const definition = getDefinitionByCode(internalCode);\n\n  // Extract value\n  let value: number | string;\n  let unit = '';\n  let isQualitative = false;\n\n  if (observation.valueQuantity?.value !== undefined) {\n    value = observation.valueQuantity.value;\n    unit = observation.valueQuantity.unit || observation.valueQuantity.code || '';\n  } else if (observation.valueString) {\n    value = observation.valueString;\n    isQualitative = true;\n  } else {\n    return {\n      skipped: {\n        index,\n        loincCode,\n        reason: 'Observation has no value (valueQuantity or valueString)',\n        resourceType: 'Observation',\n      },\n    };\n  }\n\n  // Extract collection date (effectiveDateTime or effectivePeriod.start)\n  const collectionDate = observation.effectiveDateTime || observation.effectivePeriod?.start || '';\n  if (!collectionDate) {\n    return {\n      skipped: {\n        index,\n        loincCode,\n        reason: 'Observation has no effectiveDateTime or effectivePeriod.start',\n        resourceType: 'Observation',\n      },\n    };\n  }\n\n  // Extract reference ranges\n  let referenceMin: number | undefined;\n  let referenceMax: number | undefined;\n  let referenceKind: ImportedObservation['referenceKind'];\n  if (observation.referenceRange?.[0]) {\n    referenceMin = observation.referenceRange[0].low?.value;\n    referenceMax = observation.referenceRange[0].high?.value;\n    const meaning = observation.referenceRange[0].type?.coding?.find(\n      (c) => c.system === 'http://terminology.hl7.org/CodeSystem/referencerange-meaning',\n    )?.code;\n    if (meaning === 'normal') referenceKind = 'reference-interval';\n    else if (meaning === 'recommended') referenceKind = 'decision-threshold';\n  }\n\n  const imported: ImportedObservation = {\n    biomarkerCode: internalCode,\n    biomarkerName:\n      definition?.names.pt[0] || definition?.names.en[0] || observation.code.text || internalCode,\n    collectionDate,\n    flag: extractFlag(observation),\n    isQualitative,\n    loincCode,\n    ...(loincCode && methodVariantOf(internalCode, loincCode) && { methodLoinc: loincCode }),\n    ...(referenceKind && { referenceKind }),\n    referenceMax,\n    referenceMin,\n    unit: unit || definition?.unit || '',\n    value,\n  };\n\n  return { observation: imported };\n}\n\n/**\n * Process a complete FHIR Bundle for import\n */\nexport function processImportBundle(data: unknown): FHIRImportResult {\n  // Structural validation\n  const validationErrors = validateFHIRImportBundle(data);\n  if (validationErrors.length > 0) {\n    return {\n      errors: validationErrors,\n      imported: [],\n      skipped: [],\n      totalProcessed: 0,\n    };\n  }\n\n  const bundle = data as FHIRBundle;\n\n  // Extract observations\n  const { observations, skipped } = extractObservationsFromBundle(bundle);\n\n  // Map each observation to internal format\n  const imported: ImportedObservation[] = [];\n  const allSkipped: SkippedEntry[] = [...skipped];\n\n  for (let i = 0; i < observations.length; i++) {\n    const result = mapFHIRObservationToInternal(observations[i]!, i);\n\n    if ('observation' in result) {\n      imported.push(result.observation);\n    } else {\n      allSkipped.push(result.skipped);\n    }\n  }\n\n  return {\n    errors: [],\n    imported,\n    skipped: allSkipped,\n    totalProcessed: observations.length,\n  };\n}\n\nexport { MAX_FILE_SIZE, MAX_OBSERVATIONS };\n"]}
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Nesse tamanho, 5000 Observations dão 6,0MB\n * compactos ou 13,1MB indentados, e por isso o teto de arquivo é 15MB: cobre\n * as duas formas com folga.\n *\n * Na densidade desse mesmo histórico (16 Observations por laudo), 5000\n * equivalem a cerca de 300 laudos.\n */\nconst MAX_OBSERVATIONS = 5000;\nconst MAX_FILE_SIZE = 15 * 1024 * 1024; // 15MB\n\n/**\n * Resolve o código interno do biomarcador a partir do `code.coding`.\n *\n * LOINC primeiro, que é o vocabulário que arquivos de terceiros usam. Quando\n * não resolve, cai para o coding de códigos internos, presente nos arquivos\n * exportados pela própria plataforma.\n *\n * O fallback cobre dois casos: biomarcadores sem LOINC publicado (composição\n * corporal, densidade óssea, escore de cálcio) e arquivos antigos, exportados\n * quando esses biomarcadores saíam com o placeholder `99999-9`, que não\n * resolve para nada.\n */\nfunction resolveBiomarkerCode(observation: FHIRObservation): {\n  internalCode?: string;\n  loincCode?: string;\n  reason: string;\n} {\n  const coding = observation.code?.coding ?? [];\n  const loincCode = coding.find((c) => c.system === LOINC_SYSTEM)?.code;\n  const declaredCode = coding.find((c) => c.system === BIOMARKER_CODE_SYSTEM)?.code;\n\n  const seenCodes = [\n    ...(loincCode ? [`LOINC ${loincCode}`] : []),\n    ...(declaredCode ? [`biomarker code ${declaredCode}`] : []),\n  ];\n\n  // Três motivos distintos de descarte, que antes se confundiam num só. Sem\n  // essa separação, um arquivo em SNOMED relatava \"nenhum código encontrado\",\n  // sugerindo `coding` vazio quando na verdade o código existia e estava num\n  // system que não tratamos. Para importação de terceiros, é a diferença entre\n  // um diagnóstico acionável e um enigma.\n  let reason: string;\n  if (seenCodes.length > 0) {\n    reason = `Unknown code: ${seenCodes.join(', ')}`;\n  } else if (coding.length > 0) {\n    const systems = [...new Set(coding.map((c) => c.system ?? '(sem system)'))];\n    reason = `No code in a supported system (found: ${systems.join(', ')})`;\n  } else {\n    reason = 'No code found in observation coding';\n  }\n\n  const fromLoinc = loincCode ? loincToCode(loincCode) : undefined;\n  if (fromLoinc) return { internalCode: fromLoinc, loincCode, reason };\n\n  if (declaredCode && isValidCode(declaredCode)) {\n    // `isValidCode` aceita alias, mas alias não serve como código armazenado:\n    // 49 definições têm um, e tanto `codeToLoinc` quanto as faixas de\n    // referência são indexadas só pelo canônico. Sem normalizar, `VLDL_Cholesterol`\n    // entraria no lugar de `VLDL` e perderia o LOINC 13458-5 que ele tem.\n    // Importar um Bundle é fronteira de dados, que é onde `normalizeCode` deve\n    // ser aplicado.\n    const canonical = normalizeCode(declaredCode);\n\n    // `codeToLoinc` devolve undefined para quem não tem LOINC, que é o caso\n    // esperado aqui. O campo fica de fora em vez de receber um valor inventado.\n    return { internalCode: canonical, loincCode: codeToLoinc(canonical), reason };\n  }\n\n  return { loincCode, reason };\n}\n\n/**\n * Extract interpretation flag from Observation\n */\nfunction extractFlag(observation: FHIRObservation): 'H' | 'L' | '' {\n  const code = observation.interpretation?.[0]?.coding?.[0]?.code;\n  if (code === 'H' || code === 'HH') return 'H';\n  if (code === 'L' || code === 'LL') return 'L';\n  return '';\n}\n\n/**\n * Extract Observation resources from a FHIR Bundle\n */\nexport function extractObservationsFromBundle(bundle: FHIRBundle): {\n  observations: FHIRObservation[];\n  skipped: SkippedEntry[];\n} {\n  const observations: FHIRObservation[] = [];\n  const skipped: SkippedEntry[] = [];\n\n  for (let i = 0; i < bundle.entry.length; i++) {\n    const entry = bundle.entry[i]!;\n    if (!entry.resource) {\n      skipped.push({ index: i, reason: 'Entry has no resource' });\n      continue;\n    }\n\n    if (entry.resource.resourceType !== 'Observation') {\n      // Non-observation resources are silently skipped (Patient, DiagnosticReport, etc.)\n      continue;\n    }\n\n    if (observations.length >= MAX_OBSERVATIONS) {\n      skipped.push({ index: i, reason: `Maximum of ${MAX_OBSERVATIONS} observations exceeded` });\n      continue;\n    }\n\n    observations.push(entry.resource as FHIRObservation);\n  }\n\n  return { observations, skipped };\n}\n\n/**\n * Map a FHIR Observation to internal format using LOINC→biomarker code lookup\n */\nexport function mapFHIRObservationToInternal(\n  observation: FHIRObservation,\n  index: number,\n): { observation: ImportedObservation } | { skipped: SkippedEntry } {\n  const { internalCode, loincCode, reason } = resolveBiomarkerCode(observation);\n\n  if (!internalCode) {\n    return {\n      skipped: { index, loincCode, reason, resourceType: 'Observation' },\n    };\n  }\n\n  const definition = getDefinitionByCode(internalCode);\n\n  // Extract value\n  let value: number | string;\n  let unit = '';\n  let isQualitative = false;\n\n  if (observation.valueQuantity?.value !== undefined) {\n    value = observation.valueQuantity.value;\n    unit = observation.valueQuantity.unit || observation.valueQuantity.code || '';\n  } else if (observation.valueString) {\n    value = observation.valueString;\n    isQualitative = true;\n  } else {\n    return {\n      skipped: {\n        index,\n        loincCode,\n        reason: 'Observation has no value (valueQuantity or valueString)',\n        resourceType: 'Observation',\n      },\n    };\n  }\n\n  // Extract collection date (effectiveDateTime or effectivePeriod.start)\n  const collectionDate = observation.effectiveDateTime || observation.effectivePeriod?.start || '';\n  if (!collectionDate) {\n    return {\n      skipped: {\n        index,\n        loincCode,\n        reason: 'Observation has no effectiveDateTime or effectivePeriod.start',\n        resourceType: 'Observation',\n      },\n    };\n  }\n\n  // Extract reference ranges\n  let referenceMin: number | undefined;\n  let referenceMax: number | undefined;\n  let referenceKind: ImportedObservation['referenceKind'];\n  if (observation.referenceRange?.[0]) {\n    referenceMin = observation.referenceRange[0].low?.value;\n    referenceMax = observation.referenceRange[0].high?.value;\n    const meaning = observation.referenceRange[0].type?.coding?.find(\n      (c) => c.system === 'http://terminology.hl7.org/CodeSystem/referencerange-meaning',\n    )?.code;\n    if (meaning === 'normal') referenceKind = 'reference-interval';\n    else if (meaning === 'recommended') referenceKind = 'decision-threshold';\n  }\n\n  const imported: ImportedObservation = {\n    biomarkerCode: internalCode,\n    biomarkerName:\n      definition?.names.pt[0] || definition?.names.en[0] || observation.code.text || internalCode,\n    collectionDate,\n    flag: extractFlag(observation),\n    isQualitative,\n    loincCode,\n    ...(loincCode && methodVariantOf(internalCode, loincCode) && { methodLoinc: loincCode }),\n    ...(referenceKind && { referenceKind }),\n    referenceMax,\n    referenceMin,\n    unit: unit || definition?.unit || '',\n    value,\n  };\n\n  return { observation: imported };\n}\n\n/**\n * Process a complete FHIR Bundle for import\n */\nexport function processImportBundle(data: unknown): FHIRImportResult {\n  // Structural validation\n  const validationErrors = validateFHIRImportBundle(data);\n  if (validationErrors.length > 0) {\n    return {\n      errors: validationErrors,\n      imported: [],\n      skipped: [],\n      totalProcessed: 0,\n    };\n  }\n\n  const bundle = data as FHIRBundle;\n\n  // Extract observations\n  const { observations, skipped } = extractObservationsFromBundle(bundle);\n\n  // Map each observation to internal format\n  const imported: ImportedObservation[] = [];\n  const allSkipped: SkippedEntry[] = [...skipped];\n\n  for (let i = 0; i < observations.length; i++) {\n    const result = mapFHIRObservationToInternal(observations[i]!, i);\n\n    if ('observation' in result) {\n      imported.push(result.observation);\n    } else {\n      allSkipped.push(result.skipped);\n    }\n  }\n\n  return {\n    errors: [],\n    imported,\n    skipped: allSkipped,\n    totalProcessed: observations.length,\n  };\n}\n\nexport { MAX_FILE_SIZE, MAX_OBSERVATIONS };\n"]}

package/dist/{chunk-JES2ZLH5.cjs → chunk-BDS6CM7F.cjs}

@@ -1649,16 +1649,37 @@ var BIOMARKER_DEFINITIONS = [
     category: "rins",
     code: "BUN_Creatinine_Ratio",
     // 3097-3 é "Urea nitrogen/Creatinine [Mass Ratio]", a razão BUN/creatinina,
-    // e a faixa de referência (10-20, Tietz) é a dessa convenção. O laudo
-    // brasileiro imprime "Relação Ureia/Creatinina", cuja faixa é outra (cerca
-    // de 21-43) e cujo código é 56997-0 ("Urea/Creatinine [Mass Ratio] in
-    // Serum or Plasma"). Trocar só o código deixaria a faixa errada do outro
-    // lado; a separação em duas grandezas, como em `Glucose_Fasting`, é
-    // decisão à parte, registrada em `reference-ranges.ts`.
+    // e a faixa de referência (10-20, Tietz) é a dessa convenção. Até out/2026
+    // esta entrada também levava os nomes "Razão Ureia / Creatinina" e
+    // "Urea/Creatinine Ratio", e o laudo brasileiro, que dosa ureia e não
+    // BUN, caía aqui: como ureia ≈ BUN × 2,14, a razão ureia/creatinina sai
+    // cerca de 2,14 vezes maior, e um valor normal era sinalizado como alto
+    // contra 10-20. Os nomes de ureia foram para `Urea_Creatinine_Ratio`
+    // (56997-0), e aqui ficam só as grafias de BUN, pela mesma regra que
+    // tirou "BUN" dos nomes de `Urea`: um nome exato resolve a um exame só.
     loinc: "3097-3",
     names: {
-      en: ["BUN/Creatinine Ratio", "Urea/Creatinine Ratio"],
-      pt: ["Raz\xE3o Ureia / Creatinina"]
+      en: ["BUN/Creatinine Ratio"],
+      pt: ["Raz\xE3o BUN / Creatinina", "Raz\xE3o Nitrog\xEAnio Ureico / Creatinina"]
+    },
+    unit: "raz\xE3o"
+  },
+  {
+    category: "rins",
+    code: "Urea_Creatinine_Ratio",
+    // 56997-0 é "Urea/Creatinine [Mass Ratio] in Serum or Plasma": a mesma
+    // propriedade (MRto) e o mesmo material de 3097-3, com componente ureia
+    // em vez de nitrogênio ureico. É a razão que o laudo brasileiro imprime,
+    // porque o exame de rotina aqui é a ureia (3091-6), e não o BUN. Sem
+    // faixa de referência: o intervalo que circula (cerca de 21-43) é a
+    // conversão 10-20 × 2,14, sem fonte publicada em `sources.ts` que o
+    // sustente, e uma faixa derivada sem citação é justamente o que o teste
+    // de fontes existe para barrar. Sem faixa, o valor sai sem flag, que é
+    // melhor que o flag errado de antes.
+    loinc: "56997-0",
+    names: {
+      en: ["Urea/Creatinine Ratio"],
+      pt: ["Raz\xE3o Ureia / Creatinina", "Rela\xE7\xE3o Ureia / Creatinina"]
     },
     unit: "raz\xE3o"
   },
@@ -3598,4 +3619,4 @@ function getBiomarkersForCategories(categories, options) {
 
 
 exports.BIOMARKER_DEFINITIONS = BIOMARKER_DEFINITIONS; exports.loincToCode = loincToCode; exports.methodVariantOf = methodVariantOf; exports.codeToLoinc = codeToLoinc; exports.isValidLoinc = isValidLoinc; exports.isValidCode = isValidCode; exports.normalizeCode = normalizeCode; exports.getSexForCode = getSexForCode; exports.getDefinitionsBySex = getDefinitionsBySex; exports.getDefinitionByCode = getDefinitionByCode; exports.getDefinitionByLoinc = getDefinitionByLoinc; exports.getAllDefinitions = getAllDefinitions; exports.getVisibleDefinitions = getVisibleDefinitions; exports.getAllCodes = getAllCodes; exports.getAllLoincCodes = getAllLoincCodes; exports.generateLLMReference = generateLLMReference; exports.toBiomarkerTests = toBiomarkerTests; exports.getAllSearchPatterns = getAllSearchPatterns; exports.generateFilteredLLMReference = generateFilteredLLMReference; exports.DEXA_INDICATOR_CODES = DEXA_INDICATOR_CODES; exports.DEXA_CATEGORIES = DEXA_CATEGORIES; exports.generateDexaFullReference = generateDexaFullReference; exports.isDexaDocument = isDexaDocument; exports.CAC_INDICATOR_CODES = CAC_INDICATOR_CODES; exports.generateCacFullReference = generateCacFullReference; exports.isCacDocument = isCacDocument; exports.findCodeByName = findCodeByName; exports.validateLoincNameMatch = validateLoincNameMatch; exports.isBiomarkerVisible = isBiomarkerVisible; exports.filterVisibleBiomarkers = filterVisibleBiomarkers; exports.getBiomarkersByCategory = getBiomarkersByCategory; exports.getBiomarkersForCategories = getBiomarkersForCategories;
-//# sourceMappingURL=chunk-JES2ZLH5.cjs.map
+//# sourceMappingURL=chunk-BDS6CM7F.cjs.map