@precisa-saude/fhir 0.31.0 → 0.31.2

package/dist/{chunk-3I7VPANN.cjs.map → chunk-YX6B5YFJ.cjs.map}

@@ -1 +1 @@
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Um Bundle com `subject.reference` valendo\n * `Patient/abc` só resolve se alguma entrada tiver `fullUrl` terminando em\n * `/Patient/abc`: a referência relativa é lida contra a base do `fullUrl` da\n * entrada, que é como os exemplos da própria HL7 montam Bundle de coleção.\n *\n * Antes o `fullUrl` era `urn:uuid:observation-<laudo>-<código>`, que erra duas\n * vezes. `urn:uuid:` exige a sintaxe de UUID e aquilo não era um UUID, e num\n * Bundle de entradas `urn:uuid:` a referência precisa repetir a URN inteira,\n * então nenhuma das relativas resolvia. Um laudo de 22 marcadores saía com 24\n * erros de URN e 22 referências perdidas.\n */\n/**\n * Recurso que já tem id, e por isso pode ser endereçado numa entrada.\n *\n * No FHIR o `id` é opcional, porque um recurso pode viajar sem identidade\n * própria. Numa entrada de Bundle ele não pode: sem id não há `fullUrl`, e sem\n * `fullUrl` nenhuma referência chega ao recurso. Os conversores daqui sempre\n * atribuem um, e o tipo passa a dizer isso em vez de deixar `undefined` chegar\n * até a montagem da URL.\n */\nexport type Addressable<T> = T & { id: string };\n\n/**\n * Base dos `fullUrl`.\n *\n * Não precisa responder a uma requisição: no FHIR o `fullUrl` é identidade, não\n * endereço de download. Fica sob um domínio nosso para não colidir com a\n * identidade de recurso de outra instituição, que é o risco real de usar\n * `example.org` em dado que sai da máquina.\n */\nexport const BUNDLE_BASE_URL = 'https://precisa-saude.com.br/fhir';\n\n/**\n * Monta o `fullUrl` a partir do próprio recurso.\n *\n * Recebe o recurso em vez do tipo e do id soltos de propósito. O defeito que\n * isto substitui nasceu de montar os dois lados em separado: o `fullUrl` dizia\n * `observation-demo-Hgb` enquanto o recurso tinha id `demo-Hgb`, e ninguém\n * percebeu porque nada obrigava os dois a concordarem.\n *\n * O parâmetro pede o mínimo que a URL consome, e não a união de recursos que\n * este pacote converte. Um Bundle pode carregar qualquer recurso do R4, e quem\n * acrescenta uma entrada de um tipo que não está nessa união (um `Specimen`,\n * por exemplo) precisa do mesmo endereço, senão monta o dele e as duas formas\n * divergem outra vez.\n */\nexport const entryFullUrl = (resource: Addressable<{ resourceType: string }>): string =>\n  `${BUNDLE_BASE_URL}/${resource.resourceType}/${resource.id}`;\n","/**\n * FHIR Converter\n *\n * Converts lab results to FHIR R4 DiagnosticReport and Observation resources.\n * See: https://hl7.org/fhir/diagnosticreport.html\n */\n\nimport { codeToLoinc } from './biomarkers';\nimport { type Addressable, entryFullUrl } from './bundle-urls';\nimport { BIOMARKER_CODE_SYSTEM, LOINC_SYSTEM } from './code-systems';\nimport type {\n  FHIRBundle,\n  FHIRDiagnosticReport,\n  FHIRObservation,\n  FHIRPatient,\n  FHIRQuantity,\n  FHIRReferenceRange,\n} from './fhir-types';\nimport type { Flag, LabObservationData, LabReportData, UserProfileData } from './types';\nimport { getDefaultUnit, unitToUCUM } from './units';\n\n// Re-export all types and functions\nexport * from './fhir-types';\n\n/**\n * Convert Flag to FHIR interpretation code\n */\nfunction interpretationCode(flag: Flag): string {\n  switch (flag) {\n    case 'H':\n      return 'H'; // High\n    case 'L':\n      return 'L'; // Low\n    default:\n      return 'N'; // Normal\n  }\n}\n\n/**\n * Convert Flag to FHIR interpretation display\n */\nfunction interpretationDisplay(flag: Flag): string {\n  switch (flag) {\n    case 'H':\n      return 'High';\n    case 'L':\n      return 'Low';\n    default:\n      return 'Normal';\n  }\n}\n\n/**\n * O `coding` do sexo, que vai **dentro** do CodeableConcept do `appliesTo`.\n *\n * O nome diz `CODING` e não `APPLIES_TO` de propósito: isto não é o valor do\n * campo, é uma entrada da lista de codificações dele. O embrulho acontece no\n * uso, em `{ coding: [SEX_CODING[sex]] }`.\n *\n * É o `AdministrativeGender`, e não o v3-ObservationInterpretation nem um\n * sistema nosso: um consumidor que já lê `Patient.gender` compara os dois sem\n * tabela de tradução no meio.\n */\nconst SEX_CODING = {\n  female: {\n    code: 'female',\n    display: 'Female',\n    system: 'http://hl7.org/fhir/administrative-gender',\n  },\n  male: { code: 'male', display: 'Male', system: 'http://hl7.org/fhir/administrative-gender' },\n} as const;\n\n/**\n * Monta as faixas de referência do `Observation`.\n *\n * Duas mudanças em relação ao que existia, e as duas são sobre não perder o que\n * o laudo imprimiu.\n *\n * **Um limite só já basta.** Antes a faixa só saía com os dois, e um laudo que\n * publica \"inferior a 190 mg/dL\" ou \"superior a 60 mL/min/1,73m²\" perdia o\n * campo inteiro. O R4 trata `low` e `high` como opcionais independentes e\n * documenta o caso de um lado só, e o importador deste mesmo pacote já lia\n * `low?.value` e `high?.value` com acesso opcional: a assimetria era só do\n * escritor. Ver PRE-430.\n *\n * **Mais de uma faixa, anotada.** Laudo com uma coluna de referência por sexo\n * passa a sair com as duas, cada uma com o seu `appliesTo`, em vez de o\n * pipeline escolher uma sem saber de quem é o exame. Ver PRE-424 e PRE-425.\n */\nconst buildReferenceRanges = (\n  observation: LabObservationData,\n  sourceUnit: string,\n  ucumUnit: string,\n): FHIRReferenceRange[] => {\n  const quantity = (value: number): FHIRQuantity => ({\n    code: ucumUnit,\n    system: 'http://unitsofmeasure.org',\n    unit: sourceUnit,\n    value,\n  });\n\n  // Devolve lista, e não uma faixa: o caso sem limite nenhum vira lista vazia\n  // em vez de `undefined`, e aí os dois caminhos abaixo se compõem com\n  // `flatMap` sem ninguém precisar filtrar nada depois.\n  const toRanges = (low?: number, high?: number, sex?: 'female' | 'male'): FHIRReferenceRange[] => {\n    if (low === undefined && high === undefined) return [];\n\n    return [\n      {\n        ...(sex === undefined ? {} : { appliesTo: [{ coding: [SEX_CODING[sex]] }] }),\n        ...(high === undefined ? {} : { high: quantity(high) }),\n        ...(low === undefined ? {} : { low: quantity(low) }),\n      },\n    ];\n  };\n\n  // A lista anotada tem precedência: quando ela existe, o par simples é o\n  // resumo de uma das colunas e repeti-lo publicaria a mesma faixa duas vezes,\n  // uma delas sem dizer a quem se aplica.\n  //\n  // Lista vazia cai no par simples, igual a ausente, e isso é escolha: as duas\n  // dizem \"não tenho faixa anotada\", e tratá-las diferente faria um `[]` vindo\n  // de um `.filter()` apagar em silêncio a faixa que o chamador também mandou\n  // em `referenceMin` e `referenceMax`.\n  if (observation.referenceRanges && observation.referenceRanges.length > 0) {\n    return observation.referenceRanges.flatMap((r) => toRanges(r.low, r.high, r.appliesTo));\n  }\n\n  return toRanges(observation.referenceMin, observation.referenceMax);\n};\n\n/**\n * Convert generic lab observation to FHIR Observation\n */\nexport function labObservationToFHIR(\n  observation: LabObservationData,\n  patientId: string,\n  laboratoryName?: string,\n): Addressable<FHIRObservation> {\n  const loincCode = codeToLoinc(observation.biomarkerCode);\n  // Use default unit if source unit is empty\n  const sourceUnit =\n    observation.unit || getDefaultUnit(observation.biomarkerCode) || observation.unit;\n  const ucumUnit = unitToUCUM(sourceUnit);\n  const isQualitative = observation.isQualitative || typeof observation.value === 'string';\n\n  // Base observation structure\n  const fhirObs: Addressable<FHIRObservation> = {\n    category: [\n      {\n        coding: [\n          {\n            code: 'laboratory',\n            display: 'Laboratory',\n            system: 'http://terminology.hl7.org/CodeSystem/observation-category',\n          },\n        ],\n      },\n    ],\n    code: {\n      // Sem LOINC, o coding LOINC simplesmente não sai. Antes ia `99999-9`,\n      // que não é código LOINC nenhum: publicava sob `http://loinc.org` uma\n      // afirmação falsa, e quem consumisse o bundle confiando no system\n      // trataria aquilo como código de verdade. Composição corporal, densidade\n      // óssea e escore de cálcio não têm LOINC, e o certo é a lacuna explícita.\n      coding: [\n        ...(loincCode\n          ? [\n              {\n                code: loincCode,\n                display: observation.biomarkerName,\n                system: LOINC_SYSTEM,\n              },\n            ]\n          : []),\n        {\n          code: observation.biomarkerCode,\n          display: observation.biomarkerName,\n          system: BIOMARKER_CODE_SYSTEM,\n        },\n      ],\n      text: observation.biomarkerName,\n    },\n    effectiveDateTime: observation.collectionDate,\n    id: `${observation.reportId}-${observation.biomarkerCode}`,\n    interpretation: [\n      {\n        coding: [\n          {\n            code: interpretationCode(observation.flag),\n            display: interpretationDisplay(observation.flag),\n            system: 'http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation',\n          },\n        ],\n      },\n    ],\n    performer: laboratoryName ? [{ display: laboratoryName }] : undefined,\n    resourceType: 'Observation',\n    status: 'final',\n    subject: {\n      reference: `Patient/${patientId}`,\n    },\n  };\n\n  // Add value based on type (qualitative = string, quantitative = number)\n  if (isQualitative) {\n    fhirObs.valueString = String(observation.value);\n  } else {\n    fhirObs.valueQuantity = {\n      code: ucumUnit,\n      system: 'http://unitsofmeasure.org',\n      unit: sourceUnit,\n      value: observation.value as number,\n    };\n\n    // Reference range only applies to quantitative values\n    const referenceRange = buildReferenceRanges(observation, sourceUnit, ucumUnit);\n    if (referenceRange.length > 0) fhirObs.referenceRange = referenceRange;\n  }\n\n  return fhirObs;\n}\n\n/**\n * Convert generic lab report to FHIR DiagnosticReport\n */\nexport function labReportToFHIR(\n  report: LabReportData,\n  patientId: string,\n  observationIds: string[],\n): Addressable<FHIRDiagnosticReport> {\n  // Map processing status to FHIR status\n  let status: FHIRDiagnosticReport['status'];\n  switch (report.processingStatus) {\n    case 'complete':\n      status = 'final';\n      break;\n    case 'partial':\n      status = 'partial';\n      break;\n    case 'pending_review':\n      status = 'preliminary';\n      break;\n    default:\n      status = 'final';\n  }\n\n  return {\n    category: [\n      {\n        coding: [\n          {\n            code: 'LAB',\n            display: 'Laboratory',\n            system: 'http://terminology.hl7.org/CodeSystem/v2-0074',\n          },\n        ],\n      },\n    ],\n    code: {\n      coding: [\n        {\n          code: '11502-2', // Laboratory report\n          display: 'Laboratory report',\n          system: 'http://loinc.org',\n        },\n      ],\n      text: 'Laboratory Results',\n    },\n    conclusion:\n      report.overallStatus === 'NORMAL'\n        ? 'All results within normal limits'\n        : 'One or more abnormal results detected',\n    conclusionCode:\n      report.overallStatus === 'ANORMAL'\n        ? [\n            {\n              coding: [\n                {\n                  code: 'A',\n                  display: 'Abnormal',\n                  system: 'http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation',\n                },\n              ],\n            },\n          ]\n        : undefined,\n    effectiveDateTime: report.collectionDate,\n    id: report.reportId,\n    issued: report.createdAt,\n    performer: report.laboratoryName ? [{ display: report.laboratoryName }] : undefined,\n    resourceType: 'DiagnosticReport',\n    result: observationIds.map((id) => ({ reference: `Observation/${id}` })),\n    status,\n    subject: {\n      reference: `Patient/${patientId}`,\n    },\n  };\n}\n\n/**\n * Convert user profile to FHIR Patient\n * NOTE: CPF is intentionally excluded for privacy (LGPD compliance)\n */\nexport function userProfileToFHIR(profile: UserProfileData): Addressable<FHIRPatient> {\n  const nameParts = profile.name.split(' ');\n  const given = nameParts.slice(0, -1);\n  const family = nameParts[nameParts.length - 1] || '';\n\n  return {\n    address: profile.address\n      ? [\n          {\n            city: profile.address.city,\n            country: profile.address.country || 'BR',\n            line: [\n              profile.address.street && profile.address.number\n                ? `${profile.address.street}, ${profile.address.number}`\n                : profile.address.street,\n              profile.address.complement,\n            ].filter(Boolean) as string[],\n            postalCode: profile.address.postalCode,\n            state: profile.address.state,\n          },\n        ]\n      : undefined,\n    birthDate: profile.birthDate,\n    gender: profile.gender,\n    id: profile.userId,\n    name: [\n      {\n        family,\n        given: given.length > 0 ? given : undefined,\n        text: profile.name,\n      },\n    ],\n    resourceType: 'Patient',\n    telecom:\n      [\n        ...(profile.email ? [{ system: 'email' as const, value: profile.email }] : []),\n        ...(profile.phone ? [{ system: 'phone' as const, value: profile.phone }] : []),\n      ].length > 0\n        ? [\n            ...(profile.email ? [{ system: 'email' as const, value: profile.email }] : []),\n            ...(profile.phone ? [{ system: 'phone' as const, value: profile.phone }] : []),\n          ]\n        : undefined,\n  };\n}\n\n/**\n * Convert complete lab result to FHIR Bundle\n * This is the main function for exporting lab results to FHIR R4 format\n */\nexport function labResultToFHIRBundle(\n  report: LabReportData,\n  observations: LabObservationData[],\n  userProfile: UserProfileData,\n): FHIRBundle {\n  const patientId = userProfile.userId;\n\n  // Convert observations\n  const fhirObservations = observations.map((obs) => {\n    const resource = labObservationToFHIR(\n      { ...obs, collectionDate: report.collectionDate },\n      patientId,\n      report.laboratoryName,\n    );\n\n    return { fullUrl: entryFullUrl(resource), resource };\n  });\n\n  // Os ids vêm dos recursos já montados, e não de uma segunda montagem da mesma\n  // regra. O `DiagnosticReport.result` aponta para eles, e era aqui que a\n  // referência se separava do recurso.\n  const observationIds = fhirObservations.map((entry) => entry.resource.id);\n\n  // Convert report\n  const diagnosticReport = labReportToFHIR(report, patientId, observationIds);\n\n  // Convert patient\n  const fhirPatient = userProfileToFHIR(userProfile);\n\n  return {\n    entry: [\n      { fullUrl: entryFullUrl(fhirPatient), resource: fhirPatient },\n      { fullUrl: entryFullUrl(diagnosticReport), resource: diagnosticReport },\n      ...fhirObservations,\n    ],\n    resourceType: 'Bundle',\n    type: 'collection',\n  };\n}\n"]}
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Um Bundle com `subject.reference` valendo\n * `Patient/abc` só resolve se alguma entrada tiver `fullUrl` terminando em\n * `/Patient/abc`: a referência relativa é lida contra a base do `fullUrl` da\n * entrada, que é como os exemplos da própria HL7 montam Bundle de coleção.\n *\n * Antes o `fullUrl` era `urn:uuid:observation-<laudo>-<código>`, que erra duas\n * vezes. `urn:uuid:` exige a sintaxe de UUID e aquilo não era um UUID, e num\n * Bundle de entradas `urn:uuid:` a referência precisa repetir a URN inteira,\n * então nenhuma das relativas resolvia. Um laudo de 22 marcadores saía com 24\n * erros de URN e 22 referências perdidas.\n */\n/**\n * Recurso que já tem id, e por isso pode ser endereçado numa entrada.\n *\n * No FHIR o `id` é opcional, porque um recurso pode viajar sem identidade\n * própria. Numa entrada de Bundle ele não pode: sem id não há `fullUrl`, e sem\n * `fullUrl` nenhuma referência chega ao recurso. Os conversores daqui sempre\n * atribuem um, e o tipo passa a dizer isso em vez de deixar `undefined` chegar\n * até a montagem da URL.\n */\nexport type Addressable<T> = T & { id: string };\n\n/**\n * Base dos `fullUrl`.\n *\n * Não precisa responder a uma requisição: no FHIR o `fullUrl` é identidade, não\n * endereço de download. Fica sob um domínio nosso para não colidir com a\n * identidade de recurso de outra instituição, que é o risco real de usar\n * `example.org` em dado que sai da máquina.\n */\nexport const BUNDLE_BASE_URL = 'https://precisa-saude.com.br/fhir';\n\n/**\n * Monta o `fullUrl` a partir do próprio recurso.\n *\n * Recebe o recurso em vez do tipo e do id soltos de propósito. O defeito que\n * isto substitui nasceu de montar os dois lados em separado: o `fullUrl` dizia\n * `observation-demo-Hgb` enquanto o recurso tinha id `demo-Hgb`, e ninguém\n * percebeu porque nada obrigava os dois a concordarem.\n *\n * O parâmetro pede o mínimo que a URL consome, e não a união de recursos que\n * este pacote converte. Um Bundle pode carregar qualquer recurso do R4, e quem\n * acrescenta uma entrada de um tipo que não está nessa união (um `Specimen`,\n * por exemplo) precisa do mesmo endereço, senão monta o dele e as duas formas\n * divergem outra vez.\n */\nexport const entryFullUrl = (resource: Addressable<{ resourceType: string }>): string =>\n  `${BUNDLE_BASE_URL}/${resource.resourceType}/${resource.id}`;\n","/**\n * FHIR Converter\n *\n * Converts lab results to FHIR R4 DiagnosticReport and Observation resources.\n * See: https://hl7.org/fhir/diagnosticreport.html\n */\n\nimport { codeToLoinc } from './biomarkers';\nimport { type Addressable, entryFullUrl } from './bundle-urls';\nimport { BIOMARKER_CODE_SYSTEM, LOINC_SYSTEM } from './code-systems';\nimport type {\n  FHIRBundle,\n  FHIRDiagnosticReport,\n  FHIRObservation,\n  FHIRPatient,\n  FHIRQuantity,\n  FHIRReferenceRange,\n} from './fhir-types';\nimport type { Flag, LabObservationData, LabReportData, UserProfileData } from './types';\nimport { getDefaultUnit, unitToUCUM } from './units';\n\n// Re-export all types and functions\nexport * from './fhir-types';\n\n/**\n * Convert Flag to FHIR interpretation code\n */\nfunction interpretationCode(flag: Flag): string {\n  switch (flag) {\n    case 'H':\n      return 'H'; // High\n    case 'L':\n      return 'L'; // Low\n    default:\n      return 'N'; // Normal\n  }\n}\n\n/**\n * Convert Flag to FHIR interpretation display\n */\nfunction interpretationDisplay(flag: Flag): string {\n  switch (flag) {\n    case 'H':\n      return 'High';\n    case 'L':\n      return 'Low';\n    default:\n      return 'Normal';\n  }\n}\n\n/**\n * O `coding` do sexo, que vai **dentro** do CodeableConcept do `appliesTo`.\n *\n * O nome diz `CODING` e não `APPLIES_TO` de propósito: isto não é o valor do\n * campo, é uma entrada da lista de codificações dele. O embrulho acontece no\n * uso, em `{ coding: [SEX_CODING[sex]] }`.\n *\n * É o `AdministrativeGender`, e não o v3-ObservationInterpretation nem um\n * sistema nosso: um consumidor que já lê `Patient.gender` compara os dois sem\n * tabela de tradução no meio.\n */\nconst SEX_CODING = {\n  female: {\n    code: 'female',\n    display: 'Female',\n    system: 'http://hl7.org/fhir/administrative-gender',\n  },\n  male: { code: 'male', display: 'Male', system: 'http://hl7.org/fhir/administrative-gender' },\n} as const;\n\n/**\n * Monta as faixas de referência do `Observation`.\n *\n * Duas mudanças em relação ao que existia, e as duas são sobre não perder o que\n * o laudo imprimiu.\n *\n * **Um limite só já basta.** Antes a faixa só saía com os dois, e um laudo que\n * publica \"inferior a 190 mg/dL\" ou \"superior a 60 mL/min/1,73m²\" perdia o\n * campo inteiro. O R4 trata `low` e `high` como opcionais independentes e\n * documenta o caso de um lado só, e o importador deste mesmo pacote já lia\n * `low?.value` e `high?.value` com acesso opcional: a assimetria era só do\n * escritor. Ver PRE-430.\n *\n * **Mais de uma faixa, anotada.** Laudo com uma coluna de referência por sexo\n * passa a sair com as duas, cada uma com o seu `appliesTo`, em vez de o\n * pipeline escolher uma sem saber de quem é o exame. Ver PRE-424 e PRE-425.\n */\nconst buildReferenceRanges = (\n  observation: LabObservationData,\n  sourceUnit: string,\n  ucumUnit: string,\n): FHIRReferenceRange[] => {\n  const quantity = (value: number): FHIRQuantity => ({\n    code: ucumUnit,\n    system: 'http://unitsofmeasure.org',\n    unit: sourceUnit,\n    value,\n  });\n\n  // Devolve lista, e não uma faixa: o caso sem limite nenhum vira lista vazia\n  // em vez de `undefined`, e aí os dois caminhos abaixo se compõem com\n  // `flatMap` sem ninguém precisar filtrar nada depois.\n  const toRanges = (low?: number, high?: number, sex?: 'female' | 'male'): FHIRReferenceRange[] => {\n    if (low === undefined && high === undefined) return [];\n\n    return [\n      {\n        ...(sex === undefined ? {} : { appliesTo: [{ coding: [SEX_CODING[sex]] }] }),\n        ...(high === undefined ? {} : { high: quantity(high) }),\n        ...(low === undefined ? {} : { low: quantity(low) }),\n      },\n    ];\n  };\n\n  // A lista anotada tem precedência: quando ela existe, o par simples é o\n  // resumo de uma das colunas e repeti-lo publicaria a mesma faixa duas vezes,\n  // uma delas sem dizer a quem se aplica.\n  //\n  // Lista vazia cai no par simples, igual a ausente, e isso é escolha: as duas\n  // dizem \"não tenho faixa anotada\", e tratá-las diferente faria um `[]` vindo\n  // de um `.filter()` apagar em silêncio a faixa que o chamador também mandou\n  // em `referenceMin` e `referenceMax`.\n  if (observation.referenceRanges && observation.referenceRanges.length > 0) {\n    return observation.referenceRanges.flatMap((r) => toRanges(r.low, r.high, r.appliesTo));\n  }\n\n  return toRanges(observation.referenceMin, observation.referenceMax);\n};\n\n/**\n * Convert generic lab observation to FHIR Observation\n */\nexport function labObservationToFHIR(\n  observation: LabObservationData,\n  patientId: string,\n  laboratoryName?: string,\n): Addressable<FHIRObservation> {\n  const loincCode = codeToLoinc(observation.biomarkerCode);\n  // Use default unit if source unit is empty\n  const sourceUnit =\n    observation.unit || getDefaultUnit(observation.biomarkerCode) || observation.unit;\n  const ucumUnit = unitToUCUM(sourceUnit);\n  const isQualitative = observation.isQualitative || typeof observation.value === 'string';\n\n  // Base observation structure\n  const fhirObs: Addressable<FHIRObservation> = {\n    category: [\n      {\n        coding: [\n          {\n            code: 'laboratory',\n            display: 'Laboratory',\n            system: 'http://terminology.hl7.org/CodeSystem/observation-category',\n          },\n        ],\n      },\n    ],\n    code: {\n      // Sem LOINC, o coding LOINC simplesmente não sai. Antes ia `99999-9`,\n      // que não é código LOINC nenhum: publicava sob `http://loinc.org` uma\n      // afirmação falsa, e quem consumisse o bundle confiando no system\n      // trataria aquilo como código de verdade. Composição corporal, densidade\n      // óssea e escore de cálcio não têm LOINC, e o certo é a lacuna explícita.\n      coding: [\n        ...(loincCode\n          ? [\n              {\n                code: loincCode,\n                display: observation.biomarkerName,\n                system: LOINC_SYSTEM,\n              },\n            ]\n          : []),\n        {\n          code: observation.biomarkerCode,\n          display: observation.biomarkerName,\n          system: BIOMARKER_CODE_SYSTEM,\n        },\n      ],\n      text: observation.biomarkerName,\n    },\n    effectiveDateTime: observation.collectionDate,\n    id: `${observation.reportId}-${observation.biomarkerCode}`,\n    interpretation: [\n      {\n        coding: [\n          {\n            code: interpretationCode(observation.flag),\n            display: interpretationDisplay(observation.flag),\n            system: 'http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation',\n          },\n        ],\n      },\n    ],\n    performer: laboratoryName ? [{ display: laboratoryName }] : undefined,\n    resourceType: 'Observation',\n    status: 'final',\n    subject: {\n      reference: `Patient/${patientId}`,\n    },\n  };\n\n  // Add value based on type (qualitative = string, quantitative = number)\n  if (isQualitative) {\n    fhirObs.valueString = String(observation.value);\n  } else {\n    fhirObs.valueQuantity = {\n      code: ucumUnit,\n      system: 'http://unitsofmeasure.org',\n      unit: sourceUnit,\n      value: observation.value as number,\n    };\n\n    // Reference range only applies to quantitative values\n    const referenceRange = buildReferenceRanges(observation, sourceUnit, ucumUnit);\n    if (referenceRange.length > 0) fhirObs.referenceRange = referenceRange;\n  }\n\n  return fhirObs;\n}\n\n/**\n * Convert generic lab report to FHIR DiagnosticReport\n */\nexport function labReportToFHIR(\n  report: LabReportData,\n  patientId: string,\n  observationIds: string[],\n): Addressable<FHIRDiagnosticReport> {\n  // Map processing status to FHIR status\n  let status: FHIRDiagnosticReport['status'];\n  switch (report.processingStatus) {\n    case 'complete':\n      status = 'final';\n      break;\n    case 'partial':\n      status = 'partial';\n      break;\n    case 'pending_review':\n      status = 'preliminary';\n      break;\n    default:\n      status = 'final';\n  }\n\n  return {\n    category: [\n      {\n        coding: [\n          {\n            code: 'LAB',\n            display: 'Laboratory',\n            system: 'http://terminology.hl7.org/CodeSystem/v2-0074',\n          },\n        ],\n      },\n    ],\n    code: {\n      coding: [\n        {\n          code: '11502-2', // Laboratory report\n          display: 'Laboratory report',\n          system: 'http://loinc.org',\n        },\n      ],\n      text: 'Laboratory Results',\n    },\n    conclusion:\n      report.overallStatus === 'NORMAL'\n        ? 'All results within normal limits'\n        : 'One or more abnormal results detected',\n    conclusionCode:\n      report.overallStatus === 'ANORMAL'\n        ? [\n            {\n              coding: [\n                {\n                  code: 'A',\n                  display: 'Abnormal',\n                  system: 'http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation',\n                },\n              ],\n            },\n          ]\n        : undefined,\n    effectiveDateTime: report.collectionDate,\n    id: report.reportId,\n    issued: report.createdAt,\n    performer: report.laboratoryName ? [{ display: report.laboratoryName }] : undefined,\n    resourceType: 'DiagnosticReport',\n    result: observationIds.map((id) => ({ reference: `Observation/${id}` })),\n    status,\n    subject: {\n      reference: `Patient/${patientId}`,\n    },\n  };\n}\n\n/**\n * Convert user profile to FHIR Patient\n * NOTE: CPF is intentionally excluded for privacy (LGPD compliance)\n */\nexport function userProfileToFHIR(profile: UserProfileData): Addressable<FHIRPatient> {\n  const nameParts = profile.name.split(' ');\n  const given = nameParts.slice(0, -1);\n  const family = nameParts[nameParts.length - 1] || '';\n\n  return {\n    address: profile.address\n      ? [\n          {\n            city: profile.address.city,\n            country: profile.address.country || 'BR',\n            line: [\n              profile.address.street && profile.address.number\n                ? `${profile.address.street}, ${profile.address.number}`\n                : profile.address.street,\n              profile.address.complement,\n            ].filter(Boolean) as string[],\n            postalCode: profile.address.postalCode,\n            state: profile.address.state,\n          },\n        ]\n      : undefined,\n    birthDate: profile.birthDate,\n    gender: profile.gender,\n    id: profile.userId,\n    name: [\n      {\n        family,\n        given: given.length > 0 ? given : undefined,\n        text: profile.name,\n      },\n    ],\n    resourceType: 'Patient',\n    telecom:\n      [\n        ...(profile.email ? [{ system: 'email' as const, value: profile.email }] : []),\n        ...(profile.phone ? [{ system: 'phone' as const, value: profile.phone }] : []),\n      ].length > 0\n        ? [\n            ...(profile.email ? [{ system: 'email' as const, value: profile.email }] : []),\n            ...(profile.phone ? [{ system: 'phone' as const, value: profile.phone }] : []),\n          ]\n        : undefined,\n  };\n}\n\n/**\n * Convert complete lab result to FHIR Bundle\n * This is the main function for exporting lab results to FHIR R4 format\n */\nexport function labResultToFHIRBundle(\n  report: LabReportData,\n  observations: LabObservationData[],\n  userProfile: UserProfileData,\n): FHIRBundle {\n  const patientId = userProfile.userId;\n\n  // Convert observations\n  const fhirObservations = observations.map((obs) => {\n    const resource = labObservationToFHIR(\n      { ...obs, collectionDate: report.collectionDate },\n      patientId,\n      report.laboratoryName,\n    );\n\n    return { fullUrl: entryFullUrl(resource), resource };\n  });\n\n  // Os ids vêm dos recursos já montados, e não de uma segunda montagem da mesma\n  // regra. O `DiagnosticReport.result` aponta para eles, e era aqui que a\n  // referência se separava do recurso.\n  const observationIds = fhirObservations.map((entry) => entry.resource.id);\n\n  // Convert report\n  const diagnosticReport = labReportToFHIR(report, patientId, observationIds);\n\n  // Convert patient\n  const fhirPatient = userProfileToFHIR(userProfile);\n\n  return {\n    entry: [\n      { fullUrl: entryFullUrl(fhirPatient), resource: fhirPatient },\n      { fullUrl: entryFullUrl(diagnosticReport), resource: diagnosticReport },\n      ...fhirObservations,\n    ],\n    resourceType: 'Bundle',\n    type: 'collection',\n  };\n}\n"]}

package/dist/cli.js

@@ -2222,6 +2222,12 @@ var BIOMARKER_DEFINITIONS = [
   {
     category: "composicao-corporal",
     code: "VATVolume",
+    // A tabela de tendência do DEXA traz a seção "Visceral Adipose Tissue (VAT)"
+    // com as colunas "Fat Mass" e "Volume", e o modelo nomeia a linha com o
+    // prefixo da seção. Antes do nome abaixo, o valor era gravado com o código
+    // `UNKNOWN_` que fica aqui como alias, e o `normalizeCode` na leitura
+    // devolve as observações já gravadas para este código.
+    codeAliases: ["UNKNOWN_Visceral_Adipose_Tissue_VAT_Volume"],
     // No official LOINC code exists for visceral adipose tissue volume
     names: {
       en: [
@@ -2229,6 +2235,7 @@ var BIOMARKER_DEFINITIONS = [
         "VAT Volume",
         "VATVolume",
         "Visceral Adipose Tissue Volume",
+        "Visceral Adipose Tissue (VAT) Volume",
         "VAT",
         // "Visceral Fat" e "Gordura Visceral" nus não dizem qual das duas
         // medidas o laudo traz, então também estão no `VisceralFatLevel`. O
@@ -2250,6 +2257,9 @@ var BIOMARKER_DEFINITIONS = [
   {
     category: "composicao-corporal",
     code: "VATMass",
+    // Mesmo caso do `VATVolume`: a coluna da tendência do DEXA é "Fat Mass", e
+    // o nome chega como "Visceral Adipose Tissue (VAT) Fat Mass".
+    codeAliases: ["UNKNOWN_Visceral_Adipose_Tissue_VAT_Fat_Mass"],
     // No official LOINC code exists for visceral adipose tissue mass
     names: {
       en: [
@@ -2257,6 +2267,9 @@ var BIOMARKER_DEFINITIONS = [
         "VAT Mass",
         "VATMass",
         "Visceral Adipose Tissue Mass",
+        "Visceral Adipose Tissue (VAT) Fat Mass",
+        "Visceral Adipose Tissue Fat Mass",
+        "VAT Fat Mass",
         "Visceral Adipose Tissue",
         "Visceral Mass"
       ],
@@ -4812,13 +4825,15 @@ var biomarkerRangeDefinitions = {
       }
     ]
   },
-  Basophils: {
-    default: { max: 1, min: 0, optimalMax: 0.5, optimalMin: 0, unit: "%" },
-    source: "pns-hemograma-2019"
-  },
+  // `Basophils` (%) fica sem faixa de propósito e `Basophils_Abs` usa os limites da
+  // Tabela 2 da PNS 2019. Ver o comentário em `Neutrophils_Abs`.
   Basophils_Abs: {
-    default: { max: 0.1, min: 0, optimalMax: 0.05, optimalMin: 0, unit: "K/uL" },
-    source: "pns-hemograma-2019"
+    default: { max: 0.072, min: 0, unit: "K/uL" },
+    source: "pns-hemograma-2019",
+    variants: [
+      { ageMin: 18, range: { max: 0.062, min: 0, unit: "K/uL" }, sex: "M" },
+      { ageMin: 18, range: { max: 0.072, min: 0, unit: "K/uL" }, sex: "F" }
+    ]
   },
   Bicarbonate: {
     default: { max: 29, min: 23, optimalMax: 28, optimalMin: 24, unit: "mEq/L" },
@@ -5112,14 +5127,15 @@ var biomarkerRangeDefinitions = {
     // alterado qualquer idoso com função preservada.
     source: "kdigo-ckd-2024"
   },
-  Eosinophils: {
-    default: { max: 5, min: 0, optimalMax: 4, optimalMin: 1, unit: "%" },
-    direction: "lower-better",
-    source: "pns-hemograma-2019"
-  },
+  // `Eosinophils` (%) fica sem faixa de propósito e `Eosinophils_Abs` usa os limites da
+  // Tabela 2 da PNS 2019. Ver o comentário em `Neutrophils_Abs`.
   Eosinophils_Abs: {
-    default: { max: 0.5, min: 0, optimalMax: 0.3, optimalMin: 0, unit: "K/uL" },
-    source: "pns-hemograma-2019"
+    default: { max: 0.66, min: 0, unit: "K/uL" },
+    source: "pns-hemograma-2019",
+    variants: [
+      { ageMin: 18, range: { max: 0.66, min: 0, unit: "K/uL" }, sex: "M" },
+      { ageMin: 18, range: { max: 0.55, min: 0, unit: "K/uL" }, sex: "F" }
+    ]
   },
   Omega3_EPA: {
     default: { max: 3.5, min: 0.5, optimalMax: 2.5, optimalMin: 1, unit: "%" },
@@ -5571,13 +5587,15 @@ var biomarkerRangeDefinitions = {
     direction: "lower-better",
     source: "sbc-lipids-2025"
   },
-  Lymphocytes: {
-    default: { max: 40, min: 20, optimalMax: 35, optimalMin: 25, unit: "%" },
-    source: "pns-hemograma-2019"
-  },
+  // `Lymphocytes` (%) fica sem faixa de propósito e `Lymphocytes_Abs` usa os limites da
+  // Tabela 2 da PNS 2019. Ver o comentário em `Neutrophils_Abs`.
   Lymphocytes_Abs: {
-    default: { max: 4, min: 1, optimalMax: 3, optimalMin: 1.5, unit: "K/uL" },
-    source: "pns-hemograma-2019"
+    default: { max: 3.414, min: 0.72, unit: "K/uL" },
+    source: "pns-hemograma-2019",
+    variants: [
+      { ageMin: 18, range: { max: 3.37, min: 0.72, unit: "K/uL" }, sex: "M" },
+      { ageMin: 18, range: { max: 3.414, min: 0.796, unit: "K/uL" }, sex: "F" }
+    ]
   },
   Magnesium: {
     default: { max: 2.2, min: 1.7, optimalMax: 2.1, optimalMin: 1.9, unit: "mg/dL" },
@@ -5611,13 +5629,15 @@ var biomarkerRangeDefinitions = {
     default: { max: 378, min: 0, optimalMax: 270, optimalMin: 0, unit: "nmol/L" },
     source: "tietz-7ed-2015"
   },
-  Monocytes: {
-    default: { max: 8, min: 2, optimalMax: 7, optimalMin: 3, unit: "%" },
-    source: "pns-hemograma-2019"
-  },
+  // `Monocytes` (%) fica sem faixa de propósito e `Monocytes_Abs` usa os limites da
+  // Tabela 2 da PNS 2019. Ver o comentário em `Neutrophils_Abs`.
   Monocytes_Abs: {
-    default: { max: 0.8, min: 0.2, optimalMax: 0.7, optimalMin: 0.3, unit: "K/uL" },
-    source: "pns-hemograma-2019"
+    default: { max: 0.812, min: 0.011, unit: "K/uL" },
+    source: "pns-hemograma-2019",
+    variants: [
+      { ageMin: 18, range: { max: 0.812, min: 0.011, unit: "K/uL" }, sex: "M" },
+      { ageMin: 18, range: { max: 0.692, min: 0.022, unit: "K/uL" }, sex: "F" }
+    ]
   },
   MPV: {
     default: { max: 11.5, min: 7.5, optimalMax: 10.5, optimalMin: 8, unit: "fL" },
@@ -5628,15 +5648,32 @@ var biomarkerRangeDefinitions = {
     default: { max: 470, min: 0, optimalMax: 322, optimalMin: 0, unit: "pmol/L" },
     source: "meuwese-mpo-2007"
   },
-  // WBC Differential (%)
-  Neutrophils: {
-    default: { max: 70, min: 40, optimalMax: 65, optimalMin: 50, unit: "%" },
-    source: "pns-hemograma-2019"
-  },
-  // WBC Differential (Absolute)
+  // Leucograma diferencial em percentual (`Neutrophils`, `Lymphocytes`,
+  // `Monocytes`, `Eosinophils`, `Basophils`) fica sem faixa de propósito.
+  // As faixas em % que existiam aqui citavam `pns-hemograma-2019`, mas o
+  // artigo (ROSENFELD et al., Rev. Bras. Epidemiol., v. 22, supl. 2, 2019,
+  // DOI 10.1590/1980-549720190003.supl.2) publica o diferencial só em
+  // contagem absoluta por mm³, separado por sexo (Tabela 2: basófilos 0–62
+  // em homens e 0–72 em mulheres, eosinófilos 0–660 e 0–550, e assim por
+  // diante). Não há intervalo percentual em nenhuma tabela. Sem fonte, a
+  // lacuna é melhor que um intervalo inventado: o consumidor usa a faixa
+  // impressa no laudo, como já acontece com `Glucose`.
+  //
+  // Diferencial absoluto (`*_Abs`): limites inferior e superior da Tabela 2
+  // do mesmo artigo, por sexo, exatamente como publicados. São limites da
+  // distribuição amostral de adultos (18 anos ou mais), não cortes clínicos.
+  // O artigo informa células/mm³ (= células/µL); aqui a unidade é K/uL, então
+  // cada limite foi dividido por 1.000 sem arredondar (62/mm³ = 0,062 K/uL).
+  // O artigo não publica faixa ótima, por isso não há optimalMin/optimalMax.
+  // Quando o sexo não é informado, o default é a união das duas faixas
+  // (menor mínimo e maior máximo entre homens e mulheres).
   Neutrophils_Abs: {
-    default: { max: 8, min: 1.5, optimalMax: 6, optimalMin: 2, unit: "K/uL" },
-    source: "pns-hemograma-2019"
+    default: { max: 6.474, min: 0.576, unit: "K/uL" },
+    source: "pns-hemograma-2019",
+    variants: [
+      { ageMin: 18, range: { max: 5.971, min: 0.576, unit: "K/uL" }, sex: "M" },
+      { ageMin: 18, range: { max: 6.474, min: 0.612, unit: "K/uL" }, sex: "F" }
+    ]
   },
   NonHDL_Cholesterol: {
     default: { max: 130, min: 0, optimalMax: 100, optimalMin: 0, unit: "mg/dL" },
@@ -6755,7 +6792,7 @@ async function main() {
     strict: false
   });
   if (values.version) {
-    process.stdout.write(`${"0.31.0"}
+    process.stdout.write(`${"0.31.2"}
 `);
     return;
   }

package/dist/converter.cjs

@@ -3,14 +3,14 @@
 
 
 
-var _chunk3I7VPANNcjs = require('./chunk-3I7VPANN.cjs');
+var _chunkYX6B5YFJcjs = require('./chunk-YX6B5YFJ.cjs');
 require('./chunk-OR67NJDZ.cjs');
-require('./chunk-M6TGECTK.cjs');
+require('./chunk-3GN33H37.cjs');
 require('./chunk-MJ254F5K.cjs');
 
 
 
 
 
-exports.labObservationToFHIR = _chunk3I7VPANNcjs.labObservationToFHIR; exports.labReportToFHIR = _chunk3I7VPANNcjs.labReportToFHIR; exports.labResultToFHIRBundle = _chunk3I7VPANNcjs.labResultToFHIRBundle; exports.userProfileToFHIR = _chunk3I7VPANNcjs.userProfileToFHIR;
+exports.labObservationToFHIR = _chunkYX6B5YFJcjs.labObservationToFHIR; exports.labReportToFHIR = _chunkYX6B5YFJcjs.labReportToFHIR; exports.labResultToFHIRBundle = _chunkYX6B5YFJcjs.labResultToFHIRBundle; exports.userProfileToFHIR = _chunkYX6B5YFJcjs.userProfileToFHIR;
 //# sourceMappingURL=converter.cjs.map

package/dist/converter.js

@@ -3,9 +3,9 @@ import {
   labReportToFHIR,
   labResultToFHIRBundle,
   userProfileToFHIR
-} from "./chunk-TFVADOWD.js";
+} from "./chunk-WRDWLWU2.js";
 import "./chunk-A6HR4XDK.js";
-import "./chunk-CO3KLE5C.js";
+import "./chunk-FSAQ3USO.js";
 import "./chunk-R4MUCMO3.js";
 export {
   labObservationToFHIR,

package/dist/importer.cjs

@@ -4,9 +4,9 @@
 
 
 
-var _chunkOSBQUQEIcjs = require('./chunk-OSBQUQEI.cjs');
+var _chunkKL5SYSYZcjs = require('./chunk-KL5SYSYZ.cjs');
 require('./chunk-OR67NJDZ.cjs');
-require('./chunk-M6TGECTK.cjs');
+require('./chunk-3GN33H37.cjs');
 require('./chunk-3ILBFLVQ.cjs');
 
 
@@ -14,5 +14,5 @@ require('./chunk-3ILBFLVQ.cjs');
 
 
 
-exports.MAX_FILE_SIZE = _chunkOSBQUQEIcjs.MAX_FILE_SIZE; exports.MAX_OBSERVATIONS = _chunkOSBQUQEIcjs.MAX_OBSERVATIONS; exports.extractObservationsFromBundle = _chunkOSBQUQEIcjs.extractObservationsFromBundle; exports.mapFHIRObservationToInternal = _chunkOSBQUQEIcjs.mapFHIRObservationToInternal; exports.processImportBundle = _chunkOSBQUQEIcjs.processImportBundle;
+exports.MAX_FILE_SIZE = _chunkKL5SYSYZcjs.MAX_FILE_SIZE; exports.MAX_OBSERVATIONS = _chunkKL5SYSYZcjs.MAX_OBSERVATIONS; exports.extractObservationsFromBundle = _chunkKL5SYSYZcjs.extractObservationsFromBundle; exports.mapFHIRObservationToInternal = _chunkKL5SYSYZcjs.mapFHIRObservationToInternal; exports.processImportBundle = _chunkKL5SYSYZcjs.processImportBundle;
 //# sourceMappingURL=importer.cjs.map

package/dist/importer.js

@@ -4,9 +4,9 @@ import {
   extractObservationsFromBundle,
   mapFHIRObservationToInternal,
   processImportBundle
-} from "./chunk-GDYFB2SE.js";
+} from "./chunk-XX7KTBUX.js";
 import "./chunk-A6HR4XDK.js";
-import "./chunk-CO3KLE5C.js";
+import "./chunk-FSAQ3USO.js";
 import "./chunk-N3ZCOLG2.js";
 export {
   MAX_FILE_SIZE,

package/dist/index.cjs

@@ -5,14 +5,14 @@
 
 
 
-var _chunk3I7VPANNcjs = require('./chunk-3I7VPANN.cjs');
+var _chunkYX6B5YFJcjs = require('./chunk-YX6B5YFJ.cjs');
 
 
 
 
 
 
-var _chunkOSBQUQEIcjs = require('./chunk-OSBQUQEI.cjs');
+var _chunkKL5SYSYZcjs = require('./chunk-KL5SYSYZ.cjs');
 
 
 
@@ -49,7 +49,7 @@ var _chunkOR67NJDZcjs = require('./chunk-OR67NJDZ.cjs');
 
 
 
-var _chunkM6TGECTKcjs = require('./chunk-M6TGECTK.cjs');
+var _chunk3GN33H37cjs = require('./chunk-3GN33H37.cjs');
 
 
 
@@ -57,7 +57,7 @@ var _chunkM6TGECTKcjs = require('./chunk-M6TGECTK.cjs');
 
 
 
-var _chunk4NSBIPLWcjs = require('./chunk-4NSBIPLW.cjs');
+var _chunkEWX7VXN3cjs = require('./chunk-EWX7VXN3.cjs');
 
 
 
@@ -234,14 +234,14 @@ function interventionToFHIRObservation(intervention, patientId) {
 }
 function interventionsToFHIRBundle(interventions, userProfile) {
   const patientId = userProfile.userId;
-  const fhirPatient = _chunk3I7VPANNcjs.userProfileToFHIR.call(void 0, userProfile);
+  const fhirPatient = _chunkYX6B5YFJcjs.userProfileToFHIR.call(void 0, userProfile);
   const entries = interventions.map((intervention) => {
     const isMedication = intervention.type === "medication" || intervention.type === "supplement";
     const resource = isMedication ? interventionToFHIRMedicationStatement(intervention, patientId) : interventionToFHIRObservation(intervention, patientId);
-    return { fullUrl: _chunk3I7VPANNcjs.entryFullUrl.call(void 0, resource), resource };
+    return { fullUrl: _chunkYX6B5YFJcjs.entryFullUrl.call(void 0, resource), resource };
   });
   return {
-    entry: [{ fullUrl: _chunk3I7VPANNcjs.entryFullUrl.call(void 0, fhirPatient), resource: fhirPatient }, ...entries],
+    entry: [{ fullUrl: _chunkYX6B5YFJcjs.entryFullUrl.call(void 0, fhirPatient), resource: fhirPatient }, ...entries],
     resourceType: "Bundle",
     type: "collection"
   };
@@ -738,5 +738,5 @@ var specimenTypeCoding = (text) => BY_NORMALIZED_TEXT.get(normalize(text));
 
 
 
-exports.AGE_BRACKETS = AGE_BRACKETS; exports.BIOMARKER_CODE_SYSTEM = _chunkOR67NJDZcjs.BIOMARKER_CODE_SYSTEM; exports.BIOMARKER_DEFAULT_UNIT = _chunkMJ254F5Kcjs.BIOMARKER_DEFAULT_UNIT; exports.BIOMARKER_DEFINITIONS = _chunkM6TGECTKcjs.BIOMARKER_DEFINITIONS; exports.BIOMARKER_UNITS = _chunkMJ254F5Kcjs.BIOMARKER_UNITS; exports.BODY_FAT_ZONES = BODY_FAT_ZONES; exports.BR_TIPO_AMOSTRA_VALUESET = BR_TIPO_AMOSTRA_VALUESET; exports.BUNDLE_BASE_URL = _chunk3I7VPANNcjs.BUNDLE_BASE_URL; exports.CAC_INDICATOR_CODES = _chunkM6TGECTKcjs.CAC_INDICATOR_CODES; exports.CATEGORY_GROUPS = CATEGORY_GROUPS; exports.CATEGORY_SCREENING_INTERVALS = CATEGORY_SCREENING_INTERVALS; exports.DEXA_CATEGORIES = _chunkM6TGECTKcjs.DEXA_CATEGORIES; exports.DEXA_INDICATOR_CODES = _chunkM6TGECTKcjs.DEXA_INDICATOR_CODES; exports.FHIR_BRASIL_EXTENSIONS = FHIR_BRASIL_EXTENSIONS; exports.HL7_SPECIMEN_TYPE_SYSTEM = HL7_SPECIMEN_TYPE_SYSTEM; exports.IG_CANONICAL = IG_CANONICAL; exports.LOINC_SYSTEM = _chunkOR67NJDZcjs.LOINC_SYSTEM; exports.MAX_FILE_SIZE = _chunkOSBQUQEIcjs.MAX_FILE_SIZE; exports.MAX_OBSERVATIONS = _chunkOSBQUQEIcjs.MAX_OBSERVATIONS; exports.T_SCORE_ZONES = T_SCORE_ZONES; exports.UNIT_TO_UCUM = _chunkMJ254F5Kcjs.UNIT_TO_UCUM; exports.ZONE_DEFS = ZONE_DEFS; exports.applyFallbackReferenceRanges = _chunk4NSBIPLWcjs.applyFallbackReferenceRanges; exports.biomarkerRangeDefinitions = _chunk4NSBIPLWcjs.biomarkerRangeDefinitions; exports.calculateNextScreeningDate = calculateNextScreeningDate; exports.cnsToFHIRIdentifier = cnsToFHIRIdentifier; exports.codeToLoinc = _chunkM6TGECTKcjs.codeToLoinc; exports.convertUnit = _chunkMJ254F5Kcjs.convertUnit; exports.cpfToFHIRIdentifier = cpfToFHIRIdentifier; exports.defaultReferenceRanges = _chunk4NSBIPLWcjs.defaultReferenceRanges; exports.entryFullUrl = _chunk3I7VPANNcjs.entryFullUrl; exports.extractObservationsFromBundle = _chunkOSBQUQEIcjs.extractObservationsFromBundle; exports.filterVisibleBiomarkers = _chunkM6TGECTKcjs.filterVisibleBiomarkers; exports.findCodeByName = _chunkM6TGECTKcjs.findCodeByName; exports.formatCNS = formatCNS; exports.formatCPF = formatCPF; exports.generateCacFullReference = _chunkM6TGECTKcjs.generateCacFullReference; exports.generateDexaFullReference = _chunkM6TGECTKcjs.generateDexaFullReference; exports.generateFilteredLLMReference = _chunkM6TGECTKcjs.generateFilteredLLMReference; exports.generateLLMReference = _chunkM6TGECTKcjs.generateLLMReference; exports.getAllCodes = _chunkM6TGECTKcjs.getAllCodes; exports.getAllDefinitions = _chunkM6TGECTKcjs.getAllDefinitions; exports.getAllLoincCodes = _chunkM6TGECTKcjs.getAllLoincCodes; exports.getAllSearchPatterns = _chunkM6TGECTKcjs.getAllSearchPatterns; exports.getBiomarkersByCategory = _chunkM6TGECTKcjs.getBiomarkersByCategory; exports.getBiomarkersForCategories = _chunkM6TGECTKcjs.getBiomarkersForCategories; exports.getCanonicalUnit = _chunkMJ254F5Kcjs.getCanonicalUnit; exports.getCategoriesByInterval = getCategoriesByInterval; exports.getCategoryGroup = getCategoryGroup; exports.getDaysUntilScreening = getDaysUntilScreening; exports.getDefaultUnit = _chunkMJ254F5Kcjs.getDefaultUnit; exports.getDefinitionByCode = _chunkM6TGECTKcjs.getDefinitionByCode; exports.getDefinitionByLoinc = _chunkM6TGECTKcjs.getDefinitionByLoinc; exports.getDefinitionsBySex = _chunkM6TGECTKcjs.getDefinitionsBySex; exports.getDueCategories = getDueCategories; exports.getFallbackReferenceRange = _chunk4NSBIPLWcjs.getFallbackReferenceRange; exports.getRangeDirection = _chunk4NSBIPLWcjs.getRangeDirection; exports.getReferenceRange = _chunk4NSBIPLWcjs.getReferenceRange; exports.getSIUnit = _chunkMJ254F5Kcjs.getSIUnit; exports.getScreeningInterval = getScreeningInterval; exports.getSexForCode = _chunkM6TGECTKcjs.getSexForCode; exports.getVisibleDefinitions = _chunkM6TGECTKcjs.getVisibleDefinitions; exports.interventionToFHIRMedicationStatement = interventionToFHIRMedicationStatement; exports.interventionToFHIRObservation = interventionToFHIRObservation; exports.interventionsToFHIRBundle = interventionsToFHIRBundle; exports.isBiomarkerVisible = _chunkM6TGECTKcjs.isBiomarkerVisible; exports.isCacDocument = _chunkM6TGECTKcjs.isCacDocument; exports.isDexaDocument = _chunkM6TGECTKcjs.isDexaDocument; exports.isScreeningDue = isScreeningDue; exports.isValidCode = _chunkM6TGECTKcjs.isValidCode; exports.isValidLoinc = _chunkM6TGECTKcjs.isValidLoinc; exports.labObservationToFHIR = _chunk3I7VPANNcjs.labObservationToFHIR; exports.labReportToFHIR = _chunk3I7VPANNcjs.labReportToFHIR; exports.labResultToFHIRBundle = _chunk3I7VPANNcjs.labResultToFHIRBundle; exports.listMappedSubcategories = listMappedSubcategories; exports.loincToCode = _chunkM6TGECTKcjs.loincToCode; exports.mapFHIRObservationToInternal = _chunkOSBQUQEIcjs.mapFHIRObservationToInternal; exports.normalizeCode = _chunkM6TGECTKcjs.normalizeCode; exports.plural = plural; exports.pluralCount = pluralCount; exports.pluralPhrase = pluralPhrase; exports.pluralPhraseCount = pluralPhraseCount; exports.processImportBundle = _chunkOSBQUQEIcjs.processImportBundle; exports.specimenTypeCoding = specimenTypeCoding; exports.toBiomarkerTests = _chunkM6TGECTKcjs.toBiomarkerTests; exports.unitToUCUM = _chunkMJ254F5Kcjs.unitToUCUM; exports.userProfileToFHIR = _chunk3I7VPANNcjs.userProfileToFHIR; exports.validateCNS = validateCNS; exports.validateCPF = validateCPF; exports.validateFHIRDiagnosticReport = _chunk3ILBFLVQcjs.validateFHIRDiagnosticReport; exports.validateFHIRImportBundle = _chunk3ILBFLVQcjs.validateFHIRImportBundle; exports.validateFHIRObservation = _chunk3ILBFLVQcjs.validateFHIRObservation; exports.validateLoincNameMatch = _chunkM6TGECTKcjs.validateLoincNameMatch;
+exports.AGE_BRACKETS = AGE_BRACKETS; exports.BIOMARKER_CODE_SYSTEM = _chunkOR67NJDZcjs.BIOMARKER_CODE_SYSTEM; exports.BIOMARKER_DEFAULT_UNIT = _chunkMJ254F5Kcjs.BIOMARKER_DEFAULT_UNIT; exports.BIOMARKER_DEFINITIONS = _chunk3GN33H37cjs.BIOMARKER_DEFINITIONS; exports.BIOMARKER_UNITS = _chunkMJ254F5Kcjs.BIOMARKER_UNITS; exports.BODY_FAT_ZONES = BODY_FAT_ZONES; exports.BR_TIPO_AMOSTRA_VALUESET = BR_TIPO_AMOSTRA_VALUESET; exports.BUNDLE_BASE_URL = _chunkYX6B5YFJcjs.BUNDLE_BASE_URL; exports.CAC_INDICATOR_CODES = _chunk3GN33H37cjs.CAC_INDICATOR_CODES; exports.CATEGORY_GROUPS = CATEGORY_GROUPS; exports.CATEGORY_SCREENING_INTERVALS = CATEGORY_SCREENING_INTERVALS; exports.DEXA_CATEGORIES = _chunk3GN33H37cjs.DEXA_CATEGORIES; exports.DEXA_INDICATOR_CODES = _chunk3GN33H37cjs.DEXA_INDICATOR_CODES; exports.FHIR_BRASIL_EXTENSIONS = FHIR_BRASIL_EXTENSIONS; exports.HL7_SPECIMEN_TYPE_SYSTEM = HL7_SPECIMEN_TYPE_SYSTEM; exports.IG_CANONICAL = IG_CANONICAL; exports.LOINC_SYSTEM = _chunkOR67NJDZcjs.LOINC_SYSTEM; exports.MAX_FILE_SIZE = _chunkKL5SYSYZcjs.MAX_FILE_SIZE; exports.MAX_OBSERVATIONS = _chunkKL5SYSYZcjs.MAX_OBSERVATIONS; exports.T_SCORE_ZONES = T_SCORE_ZONES; exports.UNIT_TO_UCUM = _chunkMJ254F5Kcjs.UNIT_TO_UCUM; exports.ZONE_DEFS = ZONE_DEFS; exports.applyFallbackReferenceRanges = _chunkEWX7VXN3cjs.applyFallbackReferenceRanges; exports.biomarkerRangeDefinitions = _chunkEWX7VXN3cjs.biomarkerRangeDefinitions; exports.calculateNextScreeningDate = calculateNextScreeningDate; exports.cnsToFHIRIdentifier = cnsToFHIRIdentifier; exports.codeToLoinc = _chunk3GN33H37cjs.codeToLoinc; exports.convertUnit = _chunkMJ254F5Kcjs.convertUnit; exports.cpfToFHIRIdentifier = cpfToFHIRIdentifier; exports.defaultReferenceRanges = _chunkEWX7VXN3cjs.defaultReferenceRanges; exports.entryFullUrl = _chunkYX6B5YFJcjs.entryFullUrl; exports.extractObservationsFromBundle = _chunkKL5SYSYZcjs.extractObservationsFromBundle; exports.filterVisibleBiomarkers = _chunk3GN33H37cjs.filterVisibleBiomarkers; exports.findCodeByName = _chunk3GN33H37cjs.findCodeByName; exports.formatCNS = formatCNS; exports.formatCPF = formatCPF; exports.generateCacFullReference = _chunk3GN33H37cjs.generateCacFullReference; exports.generateDexaFullReference = _chunk3GN33H37cjs.generateDexaFullReference; exports.generateFilteredLLMReference = _chunk3GN33H37cjs.generateFilteredLLMReference; exports.generateLLMReference = _chunk3GN33H37cjs.generateLLMReference; exports.getAllCodes = _chunk3GN33H37cjs.getAllCodes; exports.getAllDefinitions = _chunk3GN33H37cjs.getAllDefinitions; exports.getAllLoincCodes = _chunk3GN33H37cjs.getAllLoincCodes; exports.getAllSearchPatterns = _chunk3GN33H37cjs.getAllSearchPatterns; exports.getBiomarkersByCategory = _chunk3GN33H37cjs.getBiomarkersByCategory; exports.getBiomarkersForCategories = _chunk3GN33H37cjs.getBiomarkersForCategories; exports.getCanonicalUnit = _chunkMJ254F5Kcjs.getCanonicalUnit; exports.getCategoriesByInterval = getCategoriesByInterval; exports.getCategoryGroup = getCategoryGroup; exports.getDaysUntilScreening = getDaysUntilScreening; exports.getDefaultUnit = _chunkMJ254F5Kcjs.getDefaultUnit; exports.getDefinitionByCode = _chunk3GN33H37cjs.getDefinitionByCode; exports.getDefinitionByLoinc = _chunk3GN33H37cjs.getDefinitionByLoinc; exports.getDefinitionsBySex = _chunk3GN33H37cjs.getDefinitionsBySex; exports.getDueCategories = getDueCategories; exports.getFallbackReferenceRange = _chunkEWX7VXN3cjs.getFallbackReferenceRange; exports.getRangeDirection = _chunkEWX7VXN3cjs.getRangeDirection; exports.getReferenceRange = _chunkEWX7VXN3cjs.getReferenceRange; exports.getSIUnit = _chunkMJ254F5Kcjs.getSIUnit; exports.getScreeningInterval = getScreeningInterval; exports.getSexForCode = _chunk3GN33H37cjs.getSexForCode; exports.getVisibleDefinitions = _chunk3GN33H37cjs.getVisibleDefinitions; exports.interventionToFHIRMedicationStatement = interventionToFHIRMedicationStatement; exports.interventionToFHIRObservation = interventionToFHIRObservation; exports.interventionsToFHIRBundle = interventionsToFHIRBundle; exports.isBiomarkerVisible = _chunk3GN33H37cjs.isBiomarkerVisible; exports.isCacDocument = _chunk3GN33H37cjs.isCacDocument; exports.isDexaDocument = _chunk3GN33H37cjs.isDexaDocument; exports.isScreeningDue = isScreeningDue; exports.isValidCode = _chunk3GN33H37cjs.isValidCode; exports.isValidLoinc = _chunk3GN33H37cjs.isValidLoinc; exports.labObservationToFHIR = _chunkYX6B5YFJcjs.labObservationToFHIR; exports.labReportToFHIR = _chunkYX6B5YFJcjs.labReportToFHIR; exports.labResultToFHIRBundle = _chunkYX6B5YFJcjs.labResultToFHIRBundle; exports.listMappedSubcategories = listMappedSubcategories; exports.loincToCode = _chunk3GN33H37cjs.loincToCode; exports.mapFHIRObservationToInternal = _chunkKL5SYSYZcjs.mapFHIRObservationToInternal; exports.normalizeCode = _chunk3GN33H37cjs.normalizeCode; exports.plural = plural; exports.pluralCount = pluralCount; exports.pluralPhrase = pluralPhrase; exports.pluralPhraseCount = pluralPhraseCount; exports.processImportBundle = _chunkKL5SYSYZcjs.processImportBundle; exports.specimenTypeCoding = specimenTypeCoding; exports.toBiomarkerTests = _chunk3GN33H37cjs.toBiomarkerTests; exports.unitToUCUM = _chunkMJ254F5Kcjs.unitToUCUM; exports.userProfileToFHIR = _chunkYX6B5YFJcjs.userProfileToFHIR; exports.validateCNS = validateCNS; exports.validateCPF = validateCPF; exports.validateFHIRDiagnosticReport = _chunk3ILBFLVQcjs.validateFHIRDiagnosticReport; exports.validateFHIRImportBundle = _chunk3ILBFLVQcjs.validateFHIRImportBundle; exports.validateFHIRObservation = _chunk3ILBFLVQcjs.validateFHIRObservation; exports.validateLoincNameMatch = _chunk3GN33H37cjs.validateLoincNameMatch;
 //# sourceMappingURL=index.cjs.map

package/dist/index.js

@@ -5,14 +5,14 @@ import {
   labReportToFHIR,
   labResultToFHIRBundle,
   userProfileToFHIR
-} from "./chunk-TFVADOWD.js";
+} from "./chunk-WRDWLWU2.js";
 import {
   MAX_FILE_SIZE,
   MAX_OBSERVATIONS,
   extractObservationsFromBundle,
   mapFHIRObservationToInternal,
   processImportBundle
-} from "./chunk-GDYFB2SE.js";
+} from "./chunk-XX7KTBUX.js";
 import {
   BIOMARKER_CODE_SYSTEM,
   LOINC_SYSTEM
@@ -49,7 +49,7 @@ import {
   normalizeCode,
   toBiomarkerTests,
   validateLoincNameMatch
-} from "./chunk-CO3KLE5C.js";
+} from "./chunk-FSAQ3USO.js";
 import {
   applyFallbackReferenceRanges,
   biomarkerRangeDefinitions,
@@ -57,7 +57,7 @@ import {
   getFallbackReferenceRange,
   getRangeDirection,
   getReferenceRange
-} from "./chunk-37LQWDN7.js";
+} from "./chunk-CL2HNUGG.js";
 import {
   BIOMARKER_DEFAULT_UNIT,
   BIOMARKER_UNITS,

package/dist/reference-ranges.cjs

@@ -5,7 +5,7 @@
 
 
 
-var _chunk4NSBIPLWcjs = require('./chunk-4NSBIPLW.cjs');
+var _chunkEWX7VXN3cjs = require('./chunk-EWX7VXN3.cjs');
 require('./chunk-MJ254F5K.cjs');
 
 
@@ -14,5 +14,5 @@ require('./chunk-MJ254F5K.cjs');
 
 
 
-exports.applyFallbackReferenceRanges = _chunk4NSBIPLWcjs.applyFallbackReferenceRanges; exports.biomarkerRangeDefinitions = _chunk4NSBIPLWcjs.biomarkerRangeDefinitions; exports.defaultReferenceRanges = _chunk4NSBIPLWcjs.defaultReferenceRanges; exports.getFallbackReferenceRange = _chunk4NSBIPLWcjs.getFallbackReferenceRange; exports.getRangeDirection = _chunk4NSBIPLWcjs.getRangeDirection; exports.getReferenceRange = _chunk4NSBIPLWcjs.getReferenceRange;
+exports.applyFallbackReferenceRanges = _chunkEWX7VXN3cjs.applyFallbackReferenceRanges; exports.biomarkerRangeDefinitions = _chunkEWX7VXN3cjs.biomarkerRangeDefinitions; exports.defaultReferenceRanges = _chunkEWX7VXN3cjs.defaultReferenceRanges; exports.getFallbackReferenceRange = _chunkEWX7VXN3cjs.getFallbackReferenceRange; exports.getRangeDirection = _chunkEWX7VXN3cjs.getRangeDirection; exports.getReferenceRange = _chunkEWX7VXN3cjs.getReferenceRange;
 //# sourceMappingURL=reference-ranges.cjs.map

package/dist/reference-ranges.js

@@ -5,7 +5,7 @@ import {
   getFallbackReferenceRange,
   getRangeDirection,
   getReferenceRange
-} from "./chunk-37LQWDN7.js";
+} from "./chunk-CL2HNUGG.js";
 import "./chunk-R4MUCMO3.js";
 export {
   applyFallbackReferenceRanges,

package/package.json

@@ -1,6 +1,6 @@
 {
   "name": "@precisa-saude/fhir",
-  "version": "0.31.0",
+  "version": "0.31.2",
   "description": "Tipos FHIR R4, definições de biomarcadores, faixas de referência e conversores para o ecossistema de saúde brasileiro",
   "keywords": [
     "fhir",