@precisa-saude/fhir 0.15.0 → 0.15.1

package/dist/biomarkers.cjs

@@ -30,7 +30,7 @@
 
 
 
-var _chunkEW5GLFSCcjs = require('./chunk-EW5GLFSC.cjs');
+var _chunkJCLBVPUPcjs = require('./chunk-JCLBVPUP.cjs');
 
 
 
@@ -63,5 +63,5 @@ var _chunkEW5GLFSCcjs = require('./chunk-EW5GLFSC.cjs');
 
 
 
-exports.BIOMARKER_DEFINITIONS = _chunkEW5GLFSCcjs.BIOMARKER_DEFINITIONS; exports.CAC_INDICATOR_CODES = _chunkEW5GLFSCcjs.CAC_INDICATOR_CODES; exports.DEXA_CATEGORIES = _chunkEW5GLFSCcjs.DEXA_CATEGORIES; exports.DEXA_INDICATOR_CODES = _chunkEW5GLFSCcjs.DEXA_INDICATOR_CODES; exports.codeToLoinc = _chunkEW5GLFSCcjs.codeToLoinc; exports.filterVisibleBiomarkers = _chunkEW5GLFSCcjs.filterVisibleBiomarkers; exports.findCodeByName = _chunkEW5GLFSCcjs.findCodeByName; exports.generateCacFullReference = _chunkEW5GLFSCcjs.generateCacFullReference; exports.generateDexaFullReference = _chunkEW5GLFSCcjs.generateDexaFullReference; exports.generateFilteredLLMReference = _chunkEW5GLFSCcjs.generateFilteredLLMReference; exports.generateLLMReference = _chunkEW5GLFSCcjs.generateLLMReference; exports.getAllCodes = _chunkEW5GLFSCcjs.getAllCodes; exports.getAllDefinitions = _chunkEW5GLFSCcjs.getAllDefinitions; exports.getAllLoincCodes = _chunkEW5GLFSCcjs.getAllLoincCodes; exports.getAllSearchPatterns = _chunkEW5GLFSCcjs.getAllSearchPatterns; exports.getBiomarkersByCategory = _chunkEW5GLFSCcjs.getBiomarkersByCategory; exports.getBiomarkersForCategories = _chunkEW5GLFSCcjs.getBiomarkersForCategories; exports.getDefinitionByCode = _chunkEW5GLFSCcjs.getDefinitionByCode; exports.getDefinitionByLoinc = _chunkEW5GLFSCcjs.getDefinitionByLoinc; exports.getDefinitionsBySex = _chunkEW5GLFSCcjs.getDefinitionsBySex; exports.getSexForCode = _chunkEW5GLFSCcjs.getSexForCode; exports.getVisibleDefinitions = _chunkEW5GLFSCcjs.getVisibleDefinitions; exports.isBiomarkerVisible = _chunkEW5GLFSCcjs.isBiomarkerVisible; exports.isCacDocument = _chunkEW5GLFSCcjs.isCacDocument; exports.isDexaDocument = _chunkEW5GLFSCcjs.isDexaDocument; exports.isValidCode = _chunkEW5GLFSCcjs.isValidCode; exports.isValidLoinc = _chunkEW5GLFSCcjs.isValidLoinc; exports.loincToCode = _chunkEW5GLFSCcjs.loincToCode; exports.normalizeCode = _chunkEW5GLFSCcjs.normalizeCode; exports.toBiomarkerTests = _chunkEW5GLFSCcjs.toBiomarkerTests; exports.validateLoincNameMatch = _chunkEW5GLFSCcjs.validateLoincNameMatch;
+exports.BIOMARKER_DEFINITIONS = _chunkJCLBVPUPcjs.BIOMARKER_DEFINITIONS; exports.CAC_INDICATOR_CODES = _chunkJCLBVPUPcjs.CAC_INDICATOR_CODES; exports.DEXA_CATEGORIES = _chunkJCLBVPUPcjs.DEXA_CATEGORIES; exports.DEXA_INDICATOR_CODES = _chunkJCLBVPUPcjs.DEXA_INDICATOR_CODES; exports.codeToLoinc = _chunkJCLBVPUPcjs.codeToLoinc; exports.filterVisibleBiomarkers = _chunkJCLBVPUPcjs.filterVisibleBiomarkers; exports.findCodeByName = _chunkJCLBVPUPcjs.findCodeByName; exports.generateCacFullReference = _chunkJCLBVPUPcjs.generateCacFullReference; exports.generateDexaFullReference = _chunkJCLBVPUPcjs.generateDexaFullReference; exports.generateFilteredLLMReference = _chunkJCLBVPUPcjs.generateFilteredLLMReference; exports.generateLLMReference = _chunkJCLBVPUPcjs.generateLLMReference; exports.getAllCodes = _chunkJCLBVPUPcjs.getAllCodes; exports.getAllDefinitions = _chunkJCLBVPUPcjs.getAllDefinitions; exports.getAllLoincCodes = _chunkJCLBVPUPcjs.getAllLoincCodes; exports.getAllSearchPatterns = _chunkJCLBVPUPcjs.getAllSearchPatterns; exports.getBiomarkersByCategory = _chunkJCLBVPUPcjs.getBiomarkersByCategory; exports.getBiomarkersForCategories = _chunkJCLBVPUPcjs.getBiomarkersForCategories; exports.getDefinitionByCode = _chunkJCLBVPUPcjs.getDefinitionByCode; exports.getDefinitionByLoinc = _chunkJCLBVPUPcjs.getDefinitionByLoinc; exports.getDefinitionsBySex = _chunkJCLBVPUPcjs.getDefinitionsBySex; exports.getSexForCode = _chunkJCLBVPUPcjs.getSexForCode; exports.getVisibleDefinitions = _chunkJCLBVPUPcjs.getVisibleDefinitions; exports.isBiomarkerVisible = _chunkJCLBVPUPcjs.isBiomarkerVisible; exports.isCacDocument = _chunkJCLBVPUPcjs.isCacDocument; exports.isDexaDocument = _chunkJCLBVPUPcjs.isDexaDocument; exports.isValidCode = _chunkJCLBVPUPcjs.isValidCode; exports.isValidLoinc = _chunkJCLBVPUPcjs.isValidLoinc; exports.loincToCode = _chunkJCLBVPUPcjs.loincToCode; exports.normalizeCode = _chunkJCLBVPUPcjs.normalizeCode; exports.toBiomarkerTests = _chunkJCLBVPUPcjs.toBiomarkerTests; exports.validateLoincNameMatch = _chunkJCLBVPUPcjs.validateLoincNameMatch;
 //# sourceMappingURL=biomarkers.cjs.map

package/dist/biomarkers.js

@@ -30,7 +30,7 @@ import {
   normalizeCode,
   toBiomarkerTests,
   validateLoincNameMatch
-} from "./chunk-ICSMWCVT.js";
+} from "./chunk-ZQXKRINW.js";
 export {
   BIOMARKER_DEFINITIONS,
   CAC_INDICATOR_CODES,

package/dist/{chunk-OPS7XHIL.cjs → chunk-BRP5MGME.cjs}

@@ -1,6 +1,6 @@
 "use strict";Object.defineProperty(exports, "__esModule", {value: true});
 
-var _chunkEW5GLFSCcjs = require('./chunk-EW5GLFSC.cjs');
+var _chunkJCLBVPUPcjs = require('./chunk-JCLBVPUP.cjs');
 
 
 
@@ -30,7 +30,7 @@ function interpretationDisplay(flag) {
   }
 }
 function labObservationToFHIR(observation, patientId, laboratoryName) {
-  const loincCode = _chunkEW5GLFSCcjs.codeToLoinc.call(void 0, observation.biomarkerCode) || "99999-9";
+  const loincCode = _chunkJCLBVPUPcjs.codeToLoinc.call(void 0, observation.biomarkerCode) || "99999-9";
   const sourceUnit = observation.unit || _chunkMJ254F5Kcjs.getDefaultUnit.call(void 0, observation.biomarkerCode) || observation.unit;
   const ucumUnit = _chunkMJ254F5Kcjs.unitToUCUM.call(void 0, sourceUnit);
   const isQualitative = observation.isQualitative || typeof observation.value === "string";
@@ -248,4 +248,4 @@ function labResultToFHIRBundle(report, observations, userProfile) {
 
 
 exports.labObservationToFHIR = labObservationToFHIR; exports.labReportToFHIR = labReportToFHIR; exports.userProfileToFHIR = userProfileToFHIR; exports.labResultToFHIRBundle = labResultToFHIRBundle;
-//# sourceMappingURL=chunk-OPS7XHIL.cjs.map
+//# sourceMappingURL=chunk-BRP5MGME.cjs.map

package/dist/{chunk-OPS7XHIL.cjs.map → chunk-BRP5MGME.cjs.map}

@@ -1 +1 @@
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[{ system: 'phone' as const, value: profile.phone }] : []),\n      ].length > 0\n        ? [\n            ...(profile.email ? [{ system: 'email' as const, value: profile.email }] : []),\n            ...(profile.phone ? 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[{ display: laboratoryName }] : undefined,\n    resourceType: 'Observation',\n    status: 'final',\n    subject: {\n      reference: `Patient/${patientId}`,\n    },\n  };\n\n  // Add value based on type (qualitative = string, quantitative = number)\n  if (isQualitative) {\n    fhirObs.valueString = String(observation.value);\n  } else {\n    fhirObs.valueQuantity = {\n      code: ucumUnit,\n      system: 'http://unitsofmeasure.org',\n      unit: sourceUnit,\n      value: observation.value as number,\n    };\n\n    // Reference range only applies to quantitative values\n    if (observation.referenceMin !== undefined && observation.referenceMax !== undefined) {\n      fhirObs.referenceRange = [\n        {\n          high: {\n            code: ucumUnit,\n            system: 'http://unitsofmeasure.org',\n            unit: sourceUnit,\n            value: observation.referenceMax,\n          },\n          low: {\n            code: ucumUnit,\n            system: 'http://unitsofmeasure.org',\n            unit: sourceUnit,\n            value: observation.referenceMin,\n          },\n        },\n      ];\n    }\n  }\n\n  return fhirObs;\n}\n\n/**\n * Convert generic lab report to FHIR DiagnosticReport\n */\nexport function labReportToFHIR(\n  report: LabReportData,\n  patientId: string,\n  observationIds: string[],\n): FHIRDiagnosticReport {\n  // Map processing status to FHIR status\n  let status: FHIRDiagnosticReport['status'];\n  switch (report.processingStatus) {\n    case 'complete':\n      status = 'final';\n      break;\n    case 'partial':\n      status = 'partial';\n      break;\n    case 'pending_review':\n      status = 'preliminary';\n      break;\n    default:\n      status = 'final';\n  }\n\n  return {\n    category: [\n      {\n        coding: [\n          {\n            code: 'LAB',\n            display: 'Laboratory',\n            system: 'http://terminology.hl7.org/CodeSystem/v2-0074',\n          },\n        ],\n      },\n    ],\n    code: {\n      coding: [\n        {\n          code: '11502-2', // Laboratory report\n          display: 'Laboratory report',\n          system: 'http://loinc.org',\n        },\n      ],\n      text: 'Laboratory Results',\n    },\n    conclusion:\n      report.overallStatus === 'NORMAL'\n        ? 'All results within normal limits'\n        : 'One or more abnormal results detected',\n    conclusionCode:\n      report.overallStatus === 'ANORMAL'\n        ? [\n            {\n              coding: [\n                {\n                  code: 'A',\n                  display: 'Abnormal',\n                  system: 'http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation',\n                },\n              ],\n            },\n          ]\n        : undefined,\n    effectiveDateTime: report.collectionDate,\n    id: report.reportId,\n    issued: report.createdAt,\n    performer: report.laboratoryName ? 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[{ system: 'phone' as const, value: profile.phone }] : []),\n      ].length > 0\n        ? [\n            ...(profile.email ? [{ system: 'email' as const, value: profile.email }] : []),\n            ...(profile.phone ? [{ system: 'phone' as const, value: profile.phone }] : []),\n          ]\n        : undefined,\n  };\n}\n\n/**\n * Convert complete lab result to FHIR Bundle\n * This is the main function for exporting lab results to FHIR R4 format\n */\nexport function labResultToFHIRBundle(\n  report: LabReportData,\n  observations: LabObservationData[],\n  userProfile: UserProfileData,\n): FHIRBundle {\n  const patientId = userProfile.userId;\n\n  // Convert observations\n  const fhirObservations = observations.map((obs) => ({\n    fullUrl: `urn:uuid:observation-${obs.reportId}-${obs.biomarkerCode}`,\n    resource: labObservationToFHIR(\n      { ...obs, collectionDate: report.collectionDate },\n      patientId,\n      report.laboratoryName,\n    ),\n  }));\n\n  const observationIds = observations.map(\n    (obs) => `observation-${obs.reportId}-${obs.biomarkerCode}`,\n  );\n\n  // Convert report\n  const diagnosticReport = labReportToFHIR(report, patientId, observationIds);\n\n  // Convert patient\n  const fhirPatient = userProfileToFHIR(userProfile);\n\n  return {\n    entry: [\n      {\n        fullUrl: `urn:uuid:${patientId}`,\n        resource: fhirPatient,\n      },\n      {\n        fullUrl: `urn:uuid:diagnostic-report-${report.reportId}`,\n        resource: diagnosticReport,\n      },\n      ...fhirObservations,\n    ],\n    resourceType: 'Bundle',\n    type: 'collection',\n  };\n}\n"]}

package/dist/{chunk-NR4OTNC4.js → chunk-EHJB2UOI.js}

@@ -1,6 +1,6 @@
 import {
   codeToLoinc
-} from "./chunk-ICSMWCVT.js";
+} from "./chunk-ZQXKRINW.js";
 import {
   getDefaultUnit,
   unitToUCUM
@@ -248,4 +248,4 @@ export {
   userProfileToFHIR,
   labResultToFHIRBundle
 };
-//# sourceMappingURL=chunk-NR4OTNC4.js.map
+//# sourceMappingURL=chunk-EHJB2UOI.js.map

package/dist/{chunk-4YQOKZX7.js → chunk-HMT4VBWN.js}

@@ -1,7 +1,7 @@
 import {
   getDefinitionByLoinc,
   loincToCode
-} from "./chunk-ICSMWCVT.js";
+} from "./chunk-ZQXKRINW.js";
 import {
   validateFHIRImportBundle
 } from "./chunk-N3ZCOLG2.js";
@@ -150,4 +150,4 @@ export {
   mapFHIRObservationToInternal,
   processImportBundle
 };
-//# sourceMappingURL=chunk-4YQOKZX7.js.map
+//# sourceMappingURL=chunk-HMT4VBWN.js.map

package/dist/{chunk-EW5GLFSC.cjs → chunk-JCLBVPUP.cjs}

@@ -104,9 +104,13 @@ var BIOMARKER_DEFINITIONS = [
     unit: "nmol/L"
   },
   {
+    // LOINC 43583-4 = "Lipoprotein a [Moles/volume] in Serum or Plasma" (nmol/L).
+    // Anteriormente 10835-7 ("Lipoprotein a [Mass/volume]", mg/dL),
+    // incompatível com a unidade nmol/L declarada. SBC 2025 recomenda
+    // ensaio independente de isoforma reportado em nmol/L.
     category: "coracao",
     code: "Lipoprotein_a",
-    loinc: "10835-7",
+    loinc: "43583-4",
     names: {
       en: ["Lipoprotein (a)", "Lp(a)"],
       pt: ["Lipoprote\xEDna (a)", "Lp(a)"]
@@ -1426,11 +1430,16 @@ var BIOMARKER_DEFINITIONS = [
     unit: "mg/L"
   },
   {
+    // LOINC 3091-6 = "Urea [Mass/volume] in Serum or Plasma" (mg/dL).
+    // Anteriormente 3094-0 ("Urea nitrogen", BUN), inconsistente com a faixa
+    // de referência brasileira (15-50 mg/dL) e com os nomes pt-BR (Ureia).
+    // Aliases 'BUN' e 'Blood Urea Nitrogen' removidos para evitar matching
+    // de relatórios de BUN contra faixas de Ureia (BUN ≈ Ureia / 2,14).
     category: "rins",
     code: "Urea",
-    loinc: "3094-0",
+    loinc: "3091-6",
     names: {
-      en: ["Blood Urea Nitrogen", "BUN", "Urea"],
+      en: ["Urea"],
       pt: ["Ureia", "Ur\xE9ia"]
     },
     unit: "mg/dL"
@@ -2893,4 +2902,4 @@ function getBiomarkersForCategories(categories, options) {
 
 
 exports.BIOMARKER_DEFINITIONS = BIOMARKER_DEFINITIONS; exports.loincToCode = loincToCode; exports.codeToLoinc = codeToLoinc; exports.isValidLoinc = isValidLoinc; exports.isValidCode = isValidCode; exports.normalizeCode = normalizeCode; exports.getSexForCode = getSexForCode; exports.getDefinitionsBySex = getDefinitionsBySex; exports.getDefinitionByCode = getDefinitionByCode; exports.getDefinitionByLoinc = getDefinitionByLoinc; exports.getAllDefinitions = getAllDefinitions; exports.getVisibleDefinitions = getVisibleDefinitions; exports.getAllCodes = getAllCodes; exports.getAllLoincCodes = getAllLoincCodes; exports.generateLLMReference = generateLLMReference; exports.toBiomarkerTests = toBiomarkerTests; exports.getAllSearchPatterns = getAllSearchPatterns; exports.generateFilteredLLMReference = generateFilteredLLMReference; exports.DEXA_INDICATOR_CODES = DEXA_INDICATOR_CODES; exports.DEXA_CATEGORIES = DEXA_CATEGORIES; exports.generateDexaFullReference = generateDexaFullReference; exports.isDexaDocument = isDexaDocument; exports.CAC_INDICATOR_CODES = CAC_INDICATOR_CODES; exports.generateCacFullReference = generateCacFullReference; exports.isCacDocument = isCacDocument; exports.findCodeByName = findCodeByName; exports.validateLoincNameMatch = validateLoincNameMatch; exports.isBiomarkerVisible = isBiomarkerVisible; exports.filterVisibleBiomarkers = filterVisibleBiomarkers; exports.getBiomarkersByCategory = getBiomarkersByCategory; exports.getBiomarkersForCategories = getBiomarkersForCategories;
-//# sourceMappingURL=chunk-EW5GLFSC.cjs.map
+//# sourceMappingURL=chunk-JCLBVPUP.cjs.map