@precisa-saude/fhir 0.10.1 → 0.11.0

package/dist/{chunk-O25F6G3K.cjs → chunk-NOJRDKFO.cjs}

@@ -1,7 +1,7 @@
 "use strict";Object.defineProperty(exports, "__esModule", {value: true}); function _optionalChain(ops) { let lastAccessLHS = undefined; let value = ops[0]; let i = 1; while (i < ops.length) { const op = ops[i]; const fn = ops[i + 1]; i += 2; if ((op === 'optionalAccess' || op === 'optionalCall') && value == null) { return undefined; } if (op === 'access' || op === 'optionalAccess') { lastAccessLHS = value; value = fn(value); } else if (op === 'call' || op === 'optionalCall') { value = fn((...args) => value.call(lastAccessLHS, ...args)); lastAccessLHS = undefined; } } return value; }
 
 
-var _chunk2EVQ2ESBcjs = require('./chunk-2EVQ2ESB.cjs');
+var _chunkEW5GLFSCcjs = require('./chunk-EW5GLFSC.cjs');
 
 
 var _chunk3ILBFLVQcjs = require('./chunk-3ILBFLVQ.cjs');
@@ -51,7 +51,7 @@ function mapFHIRObservationToInternal(observation, index) {
       }
     };
   }
-  const internalCode = _chunk2EVQ2ESBcjs.loincToCode.call(void 0, loincCode);
+  const internalCode = _chunkEW5GLFSCcjs.loincToCode.call(void 0, loincCode);
   if (!internalCode) {
     return {
       skipped: {
@@ -62,7 +62,7 @@ function mapFHIRObservationToInternal(observation, index) {
       }
     };
   }
-  const definition = _chunk2EVQ2ESBcjs.getDefinitionByLoinc.call(void 0, loincCode);
+  const definition = _chunkEW5GLFSCcjs.getDefinitionByLoinc.call(void 0, loincCode);
   let value;
   let unit = "";
   let isQualitative = false;
@@ -150,4 +150,4 @@ function processImportBundle(data) {
 
 
 exports.MAX_OBSERVATIONS = MAX_OBSERVATIONS; exports.MAX_FILE_SIZE = MAX_FILE_SIZE; exports.extractObservationsFromBundle = extractObservationsFromBundle; exports.mapFHIRObservationToInternal = mapFHIRObservationToInternal; exports.processImportBundle = processImportBundle;
-//# sourceMappingURL=chunk-O25F6G3K.cjs.map
+//# sourceMappingURL=chunk-NOJRDKFO.cjs.map

package/dist/{chunk-O25F6G3K.cjs.map → chunk-NOJRDKFO.cjs.map}

@@ -1 +1 @@
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package/dist/{chunk-N6J26FVW.js → chunk-NR4OTNC4.js}

@@ -1,6 +1,6 @@
 import {
   codeToLoinc
-} from "./chunk-I6H35QXI.js";
+} from "./chunk-ICSMWCVT.js";
 import {
   getDefaultUnit,
   unitToUCUM
@@ -248,4 +248,4 @@ export {
   userProfileToFHIR,
   labResultToFHIRBundle
 };
-//# sourceMappingURL=chunk-N6J26FVW.js.map
+//# sourceMappingURL=chunk-NR4OTNC4.js.map

package/dist/{chunk-PJJVDGX4.cjs → chunk-OPS7XHIL.cjs}

@@ -1,6 +1,6 @@
 "use strict";Object.defineProperty(exports, "__esModule", {value: true});
 
-var _chunk2EVQ2ESBcjs = require('./chunk-2EVQ2ESB.cjs');
+var _chunkEW5GLFSCcjs = require('./chunk-EW5GLFSC.cjs');
 
 
 
@@ -30,7 +30,7 @@ function interpretationDisplay(flag) {
   }
 }
 function labObservationToFHIR(observation, patientId, laboratoryName) {
-  const loincCode = _chunk2EVQ2ESBcjs.codeToLoinc.call(void 0, observation.biomarkerCode) || "99999-9";
+  const loincCode = _chunkEW5GLFSCcjs.codeToLoinc.call(void 0, observation.biomarkerCode) || "99999-9";
   const sourceUnit = observation.unit || _chunkMJ254F5Kcjs.getDefaultUnit.call(void 0, observation.biomarkerCode) || observation.unit;
   const ucumUnit = _chunkMJ254F5Kcjs.unitToUCUM.call(void 0, sourceUnit);
   const isQualitative = observation.isQualitative || typeof observation.value === "string";
@@ -248,4 +248,4 @@ function labResultToFHIRBundle(report, observations, userProfile) {
 
 
 exports.labObservationToFHIR = labObservationToFHIR; exports.labReportToFHIR = labReportToFHIR; exports.userProfileToFHIR = userProfileToFHIR; exports.labResultToFHIRBundle = labResultToFHIRBundle;
-//# sourceMappingURL=chunk-PJJVDGX4.cjs.map
+//# sourceMappingURL=chunk-OPS7XHIL.cjs.map

package/dist/{chunk-PJJVDGX4.cjs.map → chunk-OPS7XHIL.cjs.map}

@@ -1 +1 @@
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[{ display: laboratoryName }] : undefined,\n    resourceType: 'Observation',\n    status: 'final',\n    subject: {\n      reference: `Patient/${patientId}`,\n    },\n  };\n\n  // Add value based on type (qualitative = string, quantitative = number)\n  if (isQualitative) {\n    fhirObs.valueString = String(observation.value);\n  } else {\n    fhirObs.valueQuantity = {\n      code: ucumUnit,\n      system: 'http://unitsofmeasure.org',\n      unit: sourceUnit,\n      value: observation.value as number,\n    };\n\n    // Reference range only applies to quantitative values\n    if (observation.referenceMin !== undefined && observation.referenceMax !== undefined) {\n      fhirObs.referenceRange = [\n        {\n          high: {\n            code: ucumUnit,\n            system: 'http://unitsofmeasure.org',\n            unit: sourceUnit,\n            value: observation.referenceMax,\n          },\n          low: {\n            code: ucumUnit,\n            system: 'http://unitsofmeasure.org',\n            unit: sourceUnit,\n            value: observation.referenceMin,\n          },\n        },\n      ];\n    }\n  }\n\n  return fhirObs;\n}\n\n/**\n * Convert generic lab report to FHIR DiagnosticReport\n */\nexport function labReportToFHIR(\n  report: LabReportData,\n  patientId: string,\n  observationIds: string[],\n): FHIRDiagnosticReport {\n  // Map processing status to FHIR status\n  let status: FHIRDiagnosticReport['status'];\n  switch (report.processingStatus) {\n    case 'complete':\n      status = 'final';\n      break;\n    case 'partial':\n      status = 'partial';\n      break;\n    case 'pending_review':\n      status = 'preliminary';\n      break;\n    default:\n      status = 'final';\n  }\n\n  return {\n    category: [\n      {\n        coding: [\n          {\n            code: 'LAB',\n            display: 'Laboratory',\n            system: 'http://terminology.hl7.org/CodeSystem/v2-0074',\n          },\n        ],\n      },\n    ],\n    code: {\n      coding: [\n        {\n          code: '11502-2', // Laboratory report\n          display: 'Laboratory report',\n          system: 'http://loinc.org',\n        },\n      ],\n      text: 'Laboratory Results',\n    },\n    conclusion:\n      report.overallStatus === 'NORMAL'\n        ? 'All results within normal limits'\n        : 'One or more abnormal results detected',\n    conclusionCode:\n      report.overallStatus === 'ANORMAL'\n        ? [\n            {\n              coding: [\n                {\n                  code: 'A',\n                  display: 'Abnormal',\n                  system: 'http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation',\n                },\n              ],\n            },\n          ]\n        : undefined,\n    effectiveDateTime: report.collectionDate,\n    id: report.reportId,\n    issued: report.createdAt,\n    performer: report.laboratoryName ? [{ display: report.laboratoryName }] : undefined,\n    resourceType: 'DiagnosticReport',\n    result: observationIds.map((id) => ({ reference: `Observation/${id}` })),\n    status,\n    subject: {\n      reference: `Patient/${patientId}`,\n    },\n  };\n}\n\n/**\n * Convert user profile to FHIR Patient\n * NOTE: CPF is intentionally excluded for privacy (LGPD compliance)\n */\nexport function userProfileToFHIR(profile: UserProfileData): FHIRPatient {\n  const nameParts = profile.name.split(' ');\n  const given = nameParts.slice(0, -1);\n  const family = nameParts[nameParts.length - 1] || '';\n\n  return {\n    address: profile.address\n      ? [\n          {\n            city: profile.address.city,\n            country: profile.address.country || 'BR',\n            line: [\n              profile.address.street && profile.address.number\n                ? `${profile.address.street}, ${profile.address.number}`\n                : profile.address.street,\n              profile.address.complement,\n            ].filter(Boolean) as string[],\n            postalCode: profile.address.postalCode,\n            state: profile.address.state,\n          },\n        ]\n      : undefined,\n    birthDate: profile.birthDate,\n    gender: profile.gender,\n    id: profile.userId,\n    name: [\n      {\n        family,\n        given: given.length > 0 ? given : undefined,\n        text: profile.name,\n      },\n    ],\n    resourceType: 'Patient',\n    telecom:\n      [\n        ...(profile.email ? [{ system: 'email' as const, value: profile.email }] : []),\n        ...(profile.phone ? [{ system: 'phone' as const, value: profile.phone }] : []),\n      ].length > 0\n        ? [\n            ...(profile.email ? [{ system: 'email' as const, value: profile.email }] : []),\n            ...(profile.phone ? [{ system: 'phone' as const, value: profile.phone }] : []),\n          ]\n        : undefined,\n  };\n}\n\n/**\n * Convert complete lab result to FHIR Bundle\n * This is the main function for exporting lab results to FHIR R4 format\n */\nexport function labResultToFHIRBundle(\n  report: LabReportData,\n  observations: LabObservationData[],\n  userProfile: UserProfileData,\n): FHIRBundle {\n  const patientId = userProfile.userId;\n\n  // Convert observations\n  const fhirObservations = observations.map((obs) => ({\n    fullUrl: `urn:uuid:observation-${obs.reportId}-${obs.biomarkerCode}`,\n    resource: labObservationToFHIR(\n      { ...obs, collectionDate: report.collectionDate },\n      patientId,\n      report.laboratoryName,\n    ),\n  }));\n\n  const observationIds = observations.map(\n    (obs) => `observation-${obs.reportId}-${obs.biomarkerCode}`,\n  );\n\n  // Convert report\n  const diagnosticReport = labReportToFHIR(report, patientId, observationIds);\n\n  // Convert patient\n  const fhirPatient = userProfileToFHIR(userProfile);\n\n  return {\n    entry: [\n      {\n        fullUrl: `urn:uuid:${patientId}`,\n        resource: fhirPatient,\n      },\n      {\n        fullUrl: `urn:uuid:diagnostic-report-${report.reportId}`,\n        resource: diagnosticReport,\n      },\n      ...fhirObservations,\n    ],\n    resourceType: 'Bundle',\n    type: 'collection',\n  };\n}\n"]}

package/dist/cli.js

@@ -2436,6 +2436,210 @@ var BIOMARKER_DEFINITIONS = [
       pt: ["Z-Score Corpo Total", "Z-Score", "Escore Z", "Z-Score DMO", "Z-Score Densidade \xD3ssea"]
     },
     unit: "score"
+  },
+  // ============================================================================
+  // CARDIOVASCULAR MARKERS — Insuficiência cardíaca e dano miocárdico
+  // ============================================================================
+  {
+    category: "coracao",
+    code: "NTproBNP",
+    loinc: "33762-6",
+    names: {
+      en: ["NT-proBNP", "N-Terminal pro B-Type Natriuretic Peptide", "NT-pro-BNP"],
+      pt: ["NT-proBNP", "Pept\xEDdeo Natriur\xE9tico Tipo B N-Terminal", "Pr\xF3-BNP N-Terminal"]
+    },
+    unit: "pg/mL"
+  },
+  {
+    category: "coracao",
+    code: "BNP",
+    loinc: "30934-4",
+    names: {
+      en: ["BNP", "B-Type Natriuretic Peptide", "Brain Natriuretic Peptide"],
+      pt: ["BNP", "Pept\xEDdeo Natriur\xE9tico Tipo B", "Pept\xEDdeo Natriur\xE9tico Cerebral"]
+    },
+    unit: "pg/mL"
+  },
+  {
+    category: "coracao",
+    code: "TroponinI",
+    loinc: "49563-0",
+    names: {
+      en: ["Troponin I", "cTnI", "Cardiac Troponin I", "hs-TnI", "High-Sensitivity Troponin I"],
+      pt: ["Troponina I", "cTnI", "Troponina I Card\xEDaca", "Troponina I Ultrassens\xEDvel"]
+    },
+    unit: "ng/mL"
+  },
+  {
+    category: "coracao",
+    code: "TroponinT",
+    loinc: "6598-7",
+    names: {
+      en: ["Troponin T", "cTnT", "Cardiac Troponin T", "hs-TnT", "High-Sensitivity Troponin T"],
+      pt: ["Troponina T", "cTnT", "Troponina T Card\xEDaca", "Troponina T Ultrassens\xEDvel"]
+    },
+    unit: "ng/mL"
+  },
+  // ============================================================================
+  // COAGULATION — Coagulação
+  // ============================================================================
+  {
+    category: "sangue",
+    code: "DDimer",
+    loinc: "48066-5",
+    names: {
+      en: ["D-Dimer", "D Dimer", "Fibrin D-Dimer"],
+      pt: ["D\xEDmero-D", "D\xEDmero D", "D-D\xEDmero"]
+    },
+    unit: "ng/mL"
+  },
+  {
+    category: "sangue",
+    code: "Fibrinogen",
+    loinc: "3255-7",
+    names: {
+      en: ["Fibrinogen", "Fibrinogen Activity"],
+      pt: ["Fibrinog\xEAnio", "Atividade do Fibrinog\xEAnio"]
+    },
+    unit: "mg/dL"
+  },
+  // ============================================================================
+  // HEMATOLOGY — Hematologia adicional
+  // ============================================================================
+  {
+    category: "figado",
+    code: "LDH",
+    loinc: "2532-0",
+    names: {
+      en: ["Lactate Dehydrogenase", "LDH", "LD"],
+      pt: ["Desidrogenase L\xE1tica", "DHL", "LDH", "Lactato Desidrogenase"]
+    },
+    unit: "U/L"
+  },
+  // ============================================================================
+  // ENDOCRINE — Eixo cálcio/fósforo
+  // ============================================================================
+  {
+    category: "hormonios",
+    code: "PTH",
+    loinc: "2731-8",
+    names: {
+      en: ["Parathyroid Hormone", "PTH", "Intact PTH"],
+      pt: ["Paratorm\xF4nio", "PTH", "Horm\xF4nio da Paratireoide", "PTH Intacto"]
+    },
+    unit: "pg/mL"
+  },
+  // ============================================================================
+  // IMMUNOLOGY — Complemento e imunoglobulinas
+  // ============================================================================
+  {
+    category: "autoimunidade",
+    code: "IgM",
+    loinc: "2472-9",
+    names: {
+      en: ["Immunoglobulin M", "IgM", "Total IgM"],
+      pt: ["Imunoglobulina M", "IgM", "IgM Total"]
+    },
+    unit: "mg/dL"
+  },
+  {
+    category: "autoimunidade",
+    code: "C3",
+    loinc: "4485-3",
+    names: {
+      en: ["Complement C3", "C3"],
+      pt: ["Complemento C3", "C3", "Fra\xE7\xE3o C3 do Complemento"]
+    },
+    unit: "mg/dL"
+  },
+  {
+    category: "autoimunidade",
+    code: "C4",
+    loinc: "4498-6",
+    names: {
+      en: ["Complement C4", "C4"],
+      pt: ["Complemento C4", "C4", "Fra\xE7\xE3o C4 do Complemento"]
+    },
+    unit: "mg/dL"
+  },
+  // ============================================================================
+  // TUMOR MARKERS — Marcadores tumorais adicionais
+  // ============================================================================
+  {
+    category: "marcadores-tumorais",
+    code: "CA199",
+    loinc: "24108-3",
+    names: {
+      en: ["CA 19-9", "Carbohydrate Antigen 19-9", "CA19-9"],
+      pt: ["CA 19-9", "Ant\xEDgeno Carboidrato 19-9", "CA19-9"]
+    },
+    unit: "U/mL"
+  },
+  {
+    category: "marcadores-tumorais",
+    code: "CA153",
+    loinc: "6875-9",
+    names: {
+      en: ["CA 15-3", "Cancer Antigen 15-3", "CA15-3"],
+      pt: ["CA 15-3", "Ant\xEDgeno C\xE2ncer 15-3", "CA15-3"]
+    },
+    sex: "female",
+    unit: "U/mL"
+  },
+  {
+    category: ["saude-feminina", "marcadores-tumorais"],
+    code: "BetaHCG",
+    loinc: "19080-1",
+    names: {
+      en: ["Beta-hCG", "Beta Human Chorionic Gonadotropin", "\u03B2-hCG Quantitative", "hCG"],
+      pt: [
+        "Beta-hCG",
+        "Beta Gonadotrofina Cori\xF4nica Humana",
+        "\u03B2-hCG Quantitativo",
+        "hCG",
+        "Gonadotrofina Cori\xF4nica"
+      ]
+    },
+    unit: "mIU/mL"
+  },
+  // ============================================================================
+  // RENAL — Filtração glomerular alternativa
+  // ============================================================================
+  {
+    category: "rins",
+    code: "CystatinC",
+    loinc: "33863-2",
+    names: {
+      en: ["Cystatin C", "Cystatin-C"],
+      pt: ["Cistatina C", "Cistatina-C"]
+    },
+    unit: "mg/L"
+  },
+  // ============================================================================
+  // NUTRIENTS — Oligoelementos adicionais
+  // ============================================================================
+  {
+    category: "nutrientes",
+    code: "Selenium",
+    loinc: "5697-7",
+    names: {
+      en: ["Selenium", "Se"],
+      pt: ["Sel\xEAnio", "Se"]
+    },
+    unit: "\xB5g/L"
+  },
+  // ============================================================================
+  // METABOLIC — Cetonas séricas
+  // ============================================================================
+  {
+    category: "pancreas",
+    code: "BetaHydroxybutyrate",
+    loinc: "53060-0",
+    names: {
+      en: ["Beta-Hydroxybutyrate", "\u03B2-Hydroxybutyrate", "BHB", "Ketone Bodies"],
+      pt: ["Beta-Hidroxibutirato", "\u03B2-Hidroxibutirato", "BHB", "Corpos Cet\xF4nicos"]
+    },
+    unit: "mmol/L"
   }
 ];
 var loincToCodeMap = /* @__PURE__ */ new Map();
@@ -5798,7 +6002,7 @@ async function main() {
     strict: false
   });
   if (values.version) {
-    process.stdout.write(`${"0.10.1"}
+    process.stdout.write(`${"0.11.0"}
 `);
     return;
   }

package/dist/converter.cjs

@@ -3,13 +3,13 @@
 
 
 
-var _chunkPJJVDGX4cjs = require('./chunk-PJJVDGX4.cjs');
-require('./chunk-2EVQ2ESB.cjs');
+var _chunkOPS7XHILcjs = require('./chunk-OPS7XHIL.cjs');
+require('./chunk-EW5GLFSC.cjs');
 require('./chunk-MJ254F5K.cjs');
 
 
 
 
 
-exports.labObservationToFHIR = _chunkPJJVDGX4cjs.labObservationToFHIR; exports.labReportToFHIR = _chunkPJJVDGX4cjs.labReportToFHIR; exports.labResultToFHIRBundle = _chunkPJJVDGX4cjs.labResultToFHIRBundle; exports.userProfileToFHIR = _chunkPJJVDGX4cjs.userProfileToFHIR;
+exports.labObservationToFHIR = _chunkOPS7XHILcjs.labObservationToFHIR; exports.labReportToFHIR = _chunkOPS7XHILcjs.labReportToFHIR; exports.labResultToFHIRBundle = _chunkOPS7XHILcjs.labResultToFHIRBundle; exports.userProfileToFHIR = _chunkOPS7XHILcjs.userProfileToFHIR;
 //# sourceMappingURL=converter.cjs.map

package/dist/converter.js

@@ -3,8 +3,8 @@ import {
   labReportToFHIR,
   labResultToFHIRBundle,
   userProfileToFHIR
-} from "./chunk-N6J26FVW.js";
-import "./chunk-I6H35QXI.js";
+} from "./chunk-NR4OTNC4.js";
+import "./chunk-ICSMWCVT.js";
 import "./chunk-R4MUCMO3.js";
 export {
   labObservationToFHIR,

package/dist/importer.cjs

@@ -4,8 +4,8 @@
 
 
 
-var _chunkO25F6G3Kcjs = require('./chunk-O25F6G3K.cjs');
-require('./chunk-2EVQ2ESB.cjs');
+var _chunkNOJRDKFOcjs = require('./chunk-NOJRDKFO.cjs');
+require('./chunk-EW5GLFSC.cjs');
 require('./chunk-3ILBFLVQ.cjs');
 
 
@@ -13,5 +13,5 @@ require('./chunk-3ILBFLVQ.cjs');
 
 
 
-exports.MAX_FILE_SIZE = _chunkO25F6G3Kcjs.MAX_FILE_SIZE; exports.MAX_OBSERVATIONS = _chunkO25F6G3Kcjs.MAX_OBSERVATIONS; exports.extractObservationsFromBundle = _chunkO25F6G3Kcjs.extractObservationsFromBundle; exports.mapFHIRObservationToInternal = _chunkO25F6G3Kcjs.mapFHIRObservationToInternal; exports.processImportBundle = _chunkO25F6G3Kcjs.processImportBundle;
+exports.MAX_FILE_SIZE = _chunkNOJRDKFOcjs.MAX_FILE_SIZE; exports.MAX_OBSERVATIONS = _chunkNOJRDKFOcjs.MAX_OBSERVATIONS; exports.extractObservationsFromBundle = _chunkNOJRDKFOcjs.extractObservationsFromBundle; exports.mapFHIRObservationToInternal = _chunkNOJRDKFOcjs.mapFHIRObservationToInternal; exports.processImportBundle = _chunkNOJRDKFOcjs.processImportBundle;
 //# sourceMappingURL=importer.cjs.map

package/dist/importer.js

@@ -4,8 +4,8 @@ import {
   extractObservationsFromBundle,
   mapFHIRObservationToInternal,
   processImportBundle
-} from "./chunk-S6VJHXJF.js";
-import "./chunk-I6H35QXI.js";
+} from "./chunk-4YQOKZX7.js";
+import "./chunk-ICSMWCVT.js";
 import "./chunk-N3ZCOLG2.js";
 export {
   MAX_FILE_SIZE,

package/dist/index.cjs

@@ -3,14 +3,14 @@
 
 
 
-var _chunkPJJVDGX4cjs = require('./chunk-PJJVDGX4.cjs');
+var _chunkOPS7XHILcjs = require('./chunk-OPS7XHIL.cjs');
 
 
 
 
 
 
-var _chunkO25F6G3Kcjs = require('./chunk-O25F6G3K.cjs');
+var _chunkNOJRDKFOcjs = require('./chunk-NOJRDKFO.cjs');
 
 
 
@@ -43,7 +43,7 @@ var _chunkO25F6G3Kcjs = require('./chunk-O25F6G3K.cjs');
 
 
 
-var _chunk2EVQ2ESBcjs = require('./chunk-2EVQ2ESB.cjs');
+var _chunkEW5GLFSCcjs = require('./chunk-EW5GLFSC.cjs');
 
 
 
@@ -68,6 +68,82 @@ var _chunkMJ254F5Kcjs = require('./chunk-MJ254F5K.cjs');
 
 var _chunk3ILBFLVQcjs = require('./chunk-3ILBFLVQ.cjs');
 
+// src/category-groups.ts
+var CATEGORY_GROUPS = {
+  cardiovascular: {
+    en: "Cardiovascular",
+    pt: "Cardiovascular",
+    slug: "cardiovascular",
+    subcategories: ["coracao"]
+  },
+  "composicao-envelhecimento": {
+    en: "Body Composition & Aging",
+    pt: "Composi\xE7\xE3o Corporal e Envelhecimento",
+    slug: "composicao-envelhecimento",
+    subcategories: ["composicao-corporal", "densidade-ossea", "estresse-envelhecimento"]
+  },
+  hematologico: {
+    en: "Hematology",
+    pt: "Hematol\xF3gico",
+    slug: "hematologico",
+    subcategories: ["sangue"]
+  },
+  "hepatico-biliar": {
+    en: "Hepatic & Biliary",
+    pt: "Hep\xE1tico e Biliar",
+    slug: "hepatico-biliar",
+    subcategories: ["figado"]
+  },
+  imunologico: {
+    en: "Immunology",
+    pt: "Imunol\xF3gico",
+    slug: "imunologico",
+    subcategories: ["autoimunidade", "regulacao-imunologica"]
+  },
+  "metabolico-endocrino": {
+    en: "Metabolic & Endocrine",
+    pt: "Metab\xF3lico e End\xF3crino",
+    slug: "metabolico-endocrino",
+    subcategories: ["metabolico", "pancreas", "hormonios", "tireoide"]
+  },
+  "nutricional-ambiental": {
+    en: "Nutrition & Environmental Exposure",
+    pt: "Nutricional e Exposi\xE7\xE3o Ambiental",
+    slug: "nutricional-ambiental",
+    subcategories: ["nutrientes", "toxinas-ambientais"]
+  },
+  oncologico: {
+    en: "Oncology",
+    pt: "Oncol\xF3gico",
+    slug: "oncologico",
+    subcategories: ["marcadores-tumorais"]
+  },
+  "renal-eletrolitico": {
+    en: "Renal & Electrolytes",
+    pt: "Renal e Eletrol\xEDtico",
+    slug: "renal-eletrolitico",
+    subcategories: ["rins", "urina", "eletrolitos"]
+  },
+  "saude-reprodutiva": {
+    en: "Reproductive Health",
+    pt: "Sa\xFAde Reprodutiva",
+    slug: "saude-reprodutiva",
+    subcategories: ["saude-feminina", "saude-masculina"]
+  }
+};
+var SUBCATEGORY_TO_GROUP = /* @__PURE__ */ new Map();
+for (const group of Object.values(CATEGORY_GROUPS)) {
+  for (const sub of group.subcategories) {
+    SUBCATEGORY_TO_GROUP.set(sub, group.slug);
+  }
+}
+function getCategoryGroup(subcategory) {
+  return SUBCATEGORY_TO_GROUP.get(subcategory);
+}
+function listMappedSubcategories() {
+  return [...SUBCATEGORY_TO_GROUP.keys()];
+}
+
 // src/intervention-converter.ts
 function interventionStatus(endDate) {
   if (!endDate) return "active";
@@ -152,7 +228,7 @@ function interventionToFHIRObservation(intervention, patientId) {
 }
 function interventionsToFHIRBundle(interventions, userProfile) {
   const patientId = userProfile.userId;
-  const fhirPatient = _chunkPJJVDGX4cjs.userProfileToFHIR.call(void 0, userProfile);
+  const fhirPatient = _chunkOPS7XHILcjs.userProfileToFHIR.call(void 0, userProfile);
   const entries = interventions.map((intervention) => {
     const isMedication = intervention.type === "medication" || intervention.type === "supplement";
     const resource = isMedication ? interventionToFHIRMedicationStatement(intervention, patientId) : interventionToFHIRObservation(intervention, patientId);
@@ -612,5 +688,8 @@ function cnsToFHIRIdentifier(cns) {
 
 
 
-exports.AGE_BRACKETS = AGE_BRACKETS; exports.BIOMARKER_DEFAULT_UNIT = _chunkMJ254F5Kcjs.BIOMARKER_DEFAULT_UNIT; exports.BIOMARKER_DEFINITIONS = _chunk2EVQ2ESBcjs.BIOMARKER_DEFINITIONS; exports.BIOMARKER_UNITS = _chunkMJ254F5Kcjs.BIOMARKER_UNITS; exports.BODY_FAT_ZONES = BODY_FAT_ZONES; exports.CAC_INDICATOR_CODES = _chunk2EVQ2ESBcjs.CAC_INDICATOR_CODES; exports.CATEGORY_SCREENING_INTERVALS = CATEGORY_SCREENING_INTERVALS; exports.DEXA_CATEGORIES = _chunk2EVQ2ESBcjs.DEXA_CATEGORIES; exports.DEXA_INDICATOR_CODES = _chunk2EVQ2ESBcjs.DEXA_INDICATOR_CODES; exports.MAX_FILE_SIZE = _chunkO25F6G3Kcjs.MAX_FILE_SIZE; exports.MAX_OBSERVATIONS = _chunkO25F6G3Kcjs.MAX_OBSERVATIONS; exports.T_SCORE_ZONES = T_SCORE_ZONES; exports.UNIT_TO_UCUM = _chunkMJ254F5Kcjs.UNIT_TO_UCUM; exports.ZONE_DEFS = ZONE_DEFS; exports.applyFallbackReferenceRanges = _chunkT22Q6ML7cjs.applyFallbackReferenceRanges; exports.biomarkerRangeDefinitions = _chunkT22Q6ML7cjs.biomarkerRangeDefinitions; exports.calculateNextScreeningDate = calculateNextScreeningDate; exports.cnsToFHIRIdentifier = cnsToFHIRIdentifier; exports.codeToLoinc = _chunk2EVQ2ESBcjs.codeToLoinc; exports.convertUnit = _chunkMJ254F5Kcjs.convertUnit; exports.cpfToFHIRIdentifier = cpfToFHIRIdentifier; exports.defaultReferenceRanges = _chunkT22Q6ML7cjs.defaultReferenceRanges; exports.extractObservationsFromBundle = _chunkO25F6G3Kcjs.extractObservationsFromBundle; exports.filterVisibleBiomarkers = _chunk2EVQ2ESBcjs.filterVisibleBiomarkers; exports.findCodeByName = _chunk2EVQ2ESBcjs.findCodeByName; exports.formatCNS = formatCNS; exports.formatCPF = formatCPF; exports.generateCacFullReference = _chunk2EVQ2ESBcjs.generateCacFullReference; exports.generateDexaFullReference = _chunk2EVQ2ESBcjs.generateDexaFullReference; exports.generateFilteredLLMReference = _chunk2EVQ2ESBcjs.generateFilteredLLMReference; exports.generateLLMReference = _chunk2EVQ2ESBcjs.generateLLMReference; exports.getAllCodes = _chunk2EVQ2ESBcjs.getAllCodes; exports.getAllDefinitions = _chunk2EVQ2ESBcjs.getAllDefinitions; exports.getAllLoincCodes = _chunk2EVQ2ESBcjs.getAllLoincCodes; exports.getAllSearchPatterns = _chunk2EVQ2ESBcjs.getAllSearchPatterns; exports.getBiomarkersByCategory = _chunk2EVQ2ESBcjs.getBiomarkersByCategory; exports.getBiomarkersForCategories = _chunk2EVQ2ESBcjs.getBiomarkersForCategories; exports.getCanonicalUnit = _chunkMJ254F5Kcjs.getCanonicalUnit; exports.getCategoriesByInterval = getCategoriesByInterval; exports.getDaysUntilScreening = getDaysUntilScreening; exports.getDefaultUnit = _chunkMJ254F5Kcjs.getDefaultUnit; exports.getDefinitionByCode = _chunk2EVQ2ESBcjs.getDefinitionByCode; exports.getDefinitionByLoinc = _chunk2EVQ2ESBcjs.getDefinitionByLoinc; exports.getDefinitionsBySex = _chunk2EVQ2ESBcjs.getDefinitionsBySex; exports.getDueCategories = getDueCategories; exports.getFallbackReferenceRange = _chunkT22Q6ML7cjs.getFallbackReferenceRange; exports.getRangeDirection = _chunkT22Q6ML7cjs.getRangeDirection; exports.getReferenceRange = _chunkT22Q6ML7cjs.getReferenceRange; exports.getSIUnit = _chunkMJ254F5Kcjs.getSIUnit; exports.getScreeningInterval = getScreeningInterval; exports.getSexForCode = _chunk2EVQ2ESBcjs.getSexForCode; exports.getVisibleDefinitions = _chunk2EVQ2ESBcjs.getVisibleDefinitions; exports.interventionToFHIRMedicationStatement = interventionToFHIRMedicationStatement; exports.interventionToFHIRObservation = interventionToFHIRObservation; exports.interventionsToFHIRBundle = interventionsToFHIRBundle; exports.isBiomarkerVisible = _chunk2EVQ2ESBcjs.isBiomarkerVisible; exports.isCacDocument = _chunk2EVQ2ESBcjs.isCacDocument; exports.isDexaDocument = _chunk2EVQ2ESBcjs.isDexaDocument; exports.isScreeningDue = isScreeningDue; exports.isValidCode = _chunk2EVQ2ESBcjs.isValidCode; exports.isValidLoinc = _chunk2EVQ2ESBcjs.isValidLoinc; exports.labObservationToFHIR = _chunkPJJVDGX4cjs.labObservationToFHIR; exports.labReportToFHIR = _chunkPJJVDGX4cjs.labReportToFHIR; exports.labResultToFHIRBundle = _chunkPJJVDGX4cjs.labResultToFHIRBundle; exports.loincToCode = _chunk2EVQ2ESBcjs.loincToCode; exports.mapFHIRObservationToInternal = _chunkO25F6G3Kcjs.mapFHIRObservationToInternal; exports.normalizeCode = _chunk2EVQ2ESBcjs.normalizeCode; exports.plural = plural; exports.pluralCount = pluralCount; exports.pluralPhrase = pluralPhrase; exports.pluralPhraseCount = pluralPhraseCount; exports.processImportBundle = _chunkO25F6G3Kcjs.processImportBundle; exports.toBiomarkerTests = _chunk2EVQ2ESBcjs.toBiomarkerTests; exports.unitToUCUM = _chunkMJ254F5Kcjs.unitToUCUM; exports.userProfileToFHIR = _chunkPJJVDGX4cjs.userProfileToFHIR; exports.validateCNS = validateCNS; exports.validateCPF = validateCPF; exports.validateFHIRDiagnosticReport = _chunk3ILBFLVQcjs.validateFHIRDiagnosticReport; exports.validateFHIRImportBundle = _chunk3ILBFLVQcjs.validateFHIRImportBundle; exports.validateFHIRObservation = _chunk3ILBFLVQcjs.validateFHIRObservation; exports.validateLoincNameMatch = _chunk2EVQ2ESBcjs.validateLoincNameMatch;
+
+
+
+exports.AGE_BRACKETS = AGE_BRACKETS; exports.BIOMARKER_DEFAULT_UNIT = _chunkMJ254F5Kcjs.BIOMARKER_DEFAULT_UNIT; exports.BIOMARKER_DEFINITIONS = _chunkEW5GLFSCcjs.BIOMARKER_DEFINITIONS; exports.BIOMARKER_UNITS = _chunkMJ254F5Kcjs.BIOMARKER_UNITS; exports.BODY_FAT_ZONES = BODY_FAT_ZONES; exports.CAC_INDICATOR_CODES = _chunkEW5GLFSCcjs.CAC_INDICATOR_CODES; exports.CATEGORY_GROUPS = CATEGORY_GROUPS; exports.CATEGORY_SCREENING_INTERVALS = CATEGORY_SCREENING_INTERVALS; exports.DEXA_CATEGORIES = _chunkEW5GLFSCcjs.DEXA_CATEGORIES; exports.DEXA_INDICATOR_CODES = _chunkEW5GLFSCcjs.DEXA_INDICATOR_CODES; exports.MAX_FILE_SIZE = _chunkNOJRDKFOcjs.MAX_FILE_SIZE; exports.MAX_OBSERVATIONS = _chunkNOJRDKFOcjs.MAX_OBSERVATIONS; exports.T_SCORE_ZONES = T_SCORE_ZONES; exports.UNIT_TO_UCUM = _chunkMJ254F5Kcjs.UNIT_TO_UCUM; exports.ZONE_DEFS = ZONE_DEFS; exports.applyFallbackReferenceRanges = _chunkT22Q6ML7cjs.applyFallbackReferenceRanges; exports.biomarkerRangeDefinitions = _chunkT22Q6ML7cjs.biomarkerRangeDefinitions; exports.calculateNextScreeningDate = calculateNextScreeningDate; exports.cnsToFHIRIdentifier = cnsToFHIRIdentifier; exports.codeToLoinc = _chunkEW5GLFSCcjs.codeToLoinc; exports.convertUnit = _chunkMJ254F5Kcjs.convertUnit; exports.cpfToFHIRIdentifier = cpfToFHIRIdentifier; exports.defaultReferenceRanges = _chunkT22Q6ML7cjs.defaultReferenceRanges; exports.extractObservationsFromBundle = _chunkNOJRDKFOcjs.extractObservationsFromBundle; exports.filterVisibleBiomarkers = _chunkEW5GLFSCcjs.filterVisibleBiomarkers; exports.findCodeByName = _chunkEW5GLFSCcjs.findCodeByName; exports.formatCNS = formatCNS; exports.formatCPF = formatCPF; exports.generateCacFullReference = _chunkEW5GLFSCcjs.generateCacFullReference; exports.generateDexaFullReference = _chunkEW5GLFSCcjs.generateDexaFullReference; exports.generateFilteredLLMReference = _chunkEW5GLFSCcjs.generateFilteredLLMReference; exports.generateLLMReference = _chunkEW5GLFSCcjs.generateLLMReference; exports.getAllCodes = _chunkEW5GLFSCcjs.getAllCodes; exports.getAllDefinitions = _chunkEW5GLFSCcjs.getAllDefinitions; exports.getAllLoincCodes = _chunkEW5GLFSCcjs.getAllLoincCodes; exports.getAllSearchPatterns = _chunkEW5GLFSCcjs.getAllSearchPatterns; exports.getBiomarkersByCategory = _chunkEW5GLFSCcjs.getBiomarkersByCategory; exports.getBiomarkersForCategories = _chunkEW5GLFSCcjs.getBiomarkersForCategories; exports.getCanonicalUnit = _chunkMJ254F5Kcjs.getCanonicalUnit; exports.getCategoriesByInterval = getCategoriesByInterval; exports.getCategoryGroup = getCategoryGroup; exports.getDaysUntilScreening = getDaysUntilScreening; exports.getDefaultUnit = _chunkMJ254F5Kcjs.getDefaultUnit; exports.getDefinitionByCode = _chunkEW5GLFSCcjs.getDefinitionByCode; exports.getDefinitionByLoinc = _chunkEW5GLFSCcjs.getDefinitionByLoinc; exports.getDefinitionsBySex = _chunkEW5GLFSCcjs.getDefinitionsBySex; exports.getDueCategories = getDueCategories; exports.getFallbackReferenceRange = _chunkT22Q6ML7cjs.getFallbackReferenceRange; exports.getRangeDirection = _chunkT22Q6ML7cjs.getRangeDirection; exports.getReferenceRange = _chunkT22Q6ML7cjs.getReferenceRange; exports.getSIUnit = _chunkMJ254F5Kcjs.getSIUnit; exports.getScreeningInterval = getScreeningInterval; exports.getSexForCode = _chunkEW5GLFSCcjs.getSexForCode; exports.getVisibleDefinitions = _chunkEW5GLFSCcjs.getVisibleDefinitions; exports.interventionToFHIRMedicationStatement = interventionToFHIRMedicationStatement; exports.interventionToFHIRObservation = interventionToFHIRObservation; exports.interventionsToFHIRBundle = interventionsToFHIRBundle; exports.isBiomarkerVisible = _chunkEW5GLFSCcjs.isBiomarkerVisible; exports.isCacDocument = _chunkEW5GLFSCcjs.isCacDocument; exports.isDexaDocument = _chunkEW5GLFSCcjs.isDexaDocument; exports.isScreeningDue = isScreeningDue; exports.isValidCode = _chunkEW5GLFSCcjs.isValidCode; exports.isValidLoinc = _chunkEW5GLFSCcjs.isValidLoinc; exports.labObservationToFHIR = _chunkOPS7XHILcjs.labObservationToFHIR; exports.labReportToFHIR = _chunkOPS7XHILcjs.labReportToFHIR; exports.labResultToFHIRBundle = _chunkOPS7XHILcjs.labResultToFHIRBundle; exports.listMappedSubcategories = listMappedSubcategories; exports.loincToCode = _chunkEW5GLFSCcjs.loincToCode; exports.mapFHIRObservationToInternal = _chunkNOJRDKFOcjs.mapFHIRObservationToInternal; exports.normalizeCode = _chunkEW5GLFSCcjs.normalizeCode; exports.plural = plural; exports.pluralCount = pluralCount; exports.pluralPhrase = pluralPhrase; exports.pluralPhraseCount = pluralPhraseCount; exports.processImportBundle = _chunkNOJRDKFOcjs.processImportBundle; exports.toBiomarkerTests = _chunkEW5GLFSCcjs.toBiomarkerTests; exports.unitToUCUM = _chunkMJ254F5Kcjs.unitToUCUM; exports.userProfileToFHIR = _chunkOPS7XHILcjs.userProfileToFHIR; exports.validateCNS = validateCNS; exports.validateCPF = validateCPF; exports.validateFHIRDiagnosticReport = _chunk3ILBFLVQcjs.validateFHIRDiagnosticReport; exports.validateFHIRImportBundle = _chunk3ILBFLVQcjs.validateFHIRImportBundle; exports.validateFHIRObservation = _chunk3ILBFLVQcjs.validateFHIRObservation; exports.validateLoincNameMatch = _chunkEW5GLFSCcjs.validateLoincNameMatch;
 //# sourceMappingURL=index.cjs.map