@precisa-saude/fhir-calculators 0.10.0 → 0.11.0
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- package/README.md +21 -21
- package/package.json +2 -2
package/README.md
CHANGED
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@@ -21,19 +21,19 @@ import { phenoage } from '@precisa-saude/fhir-calculators';
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const result = phenoage.calculatePhenoAge({
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chronologicalAge: 45,
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albumin: 42,
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25
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creatinine: 80,
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glucose: 5.2,
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crp: 1.5,
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albumin: 42, // g/L
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creatinine: 80, // μmol/L
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glucose: 5.2, // mmol/L
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crp: 1.5, // mg/L
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lymphocytePercent: 30,
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mcv: 88,
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rdw: 13.2,
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mcv: 88, // fL
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rdw: 13.2, // %
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alkalinePhosphatase: 65, // U/L
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wbc: 6.0,
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wbc: 6.0, // 10^9/L
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});
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console.log(result.phenoAge);
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console.log(result.ageDifference);
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console.log(result.phenoAge); // 42.3 (idade biológica)
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console.log(result.ageDifference); // -2.7 (anos mais jovem)
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```
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### BrDMrisc — Risco de diabetes tipo 2
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@@ -44,13 +44,13 @@ Implementação do modelo BrDMrisc (Bracco et al. 2023) para estimativa de risco
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import { brdmrisc } from '@precisa-saude/fhir-calculators';
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const result = brdmrisc.calculateBrDMrisc({
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fpg: 105,
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hba1c: 5.8,
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triglycerides: 180,
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hdlc: 42,
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fpg: 105, // mg/dL — glicemia de jejum
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hba1c: 5.8, // %
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triglycerides: 180, // mg/dL
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hdlc: 42, // mg/dL
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});
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console.log(result.riskPercent);
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console.log(result.riskPercent); // 18.5 (% risco em 10 anos)
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console.log(result.riskCategory); // 'moderate'
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console.log(result.modelUsed.name); // 'FPG + HbA1c + Lipids'
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```
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@@ -69,17 +69,17 @@ const derived = computeDerivedBiomarkers([
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]);
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// Retorna: HOMA-IR = (95 × 12) / 405, VLDL = 150 / 5
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derived.forEach(d => console.log(`${d.code}: ${d.value} ${d.unit}`));
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derived.forEach((d) => console.log(`${d.code}: ${d.value} ${d.unit}`));
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```
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## Referências acadêmicas
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| Calculadora
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| PhenoAge
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| BrDMrisc
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| HOMA-IR
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| VLDL
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| Calculadora | Referência |
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| ----------- | ------------------------------------------------------------------------------------- |
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| PhenoAge | Levine ME et al. (2018). An epigenetic biomarker of aging. _Aging_ 10(4):573-591 |
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| BrDMrisc | Bracco PA et al. (2023). BrDMrisc model for type 2 diabetes risk in Brazilians |
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| HOMA-IR | Matthews DR et al. (1985). Homeostasis model assessment. _Diabetologia_ 28(7):412-419 |
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| VLDL | Friedewald WT et al. (1972). Estimation of LDL cholesterol. _Clin Chem_ 18(6):499-502 |
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## Aviso médico
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package/package.json
CHANGED
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@@ -1,6 +1,6 @@
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{
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"name": "@precisa-saude/fhir-calculators",
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"version": "0.
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"version": "0.11.0",
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"description": "Calculadoras clínicas — PhenoAge, BrDMrisc, biomarcadores derivados (HOMA-IR, VLDL, IMC)",
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"keywords": [
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"fhir",
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@@ -38,7 +38,7 @@
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"dist"
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],
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"dependencies": {
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"@precisa-saude/fhir": "^0.
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"@precisa-saude/fhir": "^0.11.0"
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},
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"devDependencies": {
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"tsup": "^8.3.5",
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