@platforma-open/milaboratories.top-antibodies 3.2.7 → 4.0.0

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@@ -6,7 +6,7 @@ Ranks and selects top lead candidates — antibodies, TCRs, or peptides — usin
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  The block offers built-in presets for common discovery workflows:
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- * **In Vivo (immunization/infection):** Ranks antibody/TCR candidates by In Vivo Score, a composite metric calculated from clonal expansion, CDR mutation frequency, and germinal center selection signals. Applies default filters on mutation-related metrics (e.g., fraction of CDR mutations, total number of mutations) to focus on immune-refined candidates.
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+ * **In Vivo (immunization/infection):** Ranks antibody/TCR candidates by the Repertoire Score exported by the upstream Repertoire Score block — a composite metric combining clonal expansion, CDR mutation frequency, and germinal center selection signals. Applies default filters on mutation-related metrics (e.g., fraction of CDR mutations, total number of mutations) to focus on immune-refined candidates.
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  * **In Vitro (display/panning):** Ranks antibody/TCR candidates by enrichment scores across selection rounds to identify clones selected for target binding.
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  * **Peptide:** Ranks peptide candidates by all available numeric score columns (typically enrichment, sequence properties, and liabilities). Suited for peptide selection campaigns where SHM-based metrics are not applicable.
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Binary file
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+ {"schema":"v2","description":{"id":{"organization":"milaboratories","name":"top-antibodies","version":"4.0.0"},"components":{"workflow":{"type":"workflow-v1","main":{"type":"relative","path":"main.plj.gz"}},"model":{"type":"relative","path":"model.json"},"ui":{"type":"relative","path":"ui.tgz"}},"meta":{"title":"Lead Selection","description":"Ranks and selects top lead candidates (antibodies, TCRs, or peptides) using configurable scoring, filtering, and diversified ranking with built-in workflow presets.","longDescription":{"type":"relative","path":"description.md"},"changelog":{"type":"relative","path":"CHANGELOG.md"},"logo":{"type":"relative","path":"block-logo.png"},"url":"https://github.com/platforma-open/antibody-tcr-lead-selection","docs":"https://docs.platforma.bio/guides/antibody-discovery/lead-selection/","support":"mailto:support@milaboratories.com","tags":["airr","downstream","peptide"],"organization":{"name":"MiLaboratories Inc","url":"https://milaboratories.com/","logo":{"type":"relative","path":"organization-logo.png"}}},"featureFlags":{"supportsLazyState":true,"supportsPframeQueryRanking":true,"requiresUIAPIVersion":3,"requiresModelAPIVersion":2,"requiresCreatePTable":2,"requiresPFramesVersion":1001031,"requiresPFrameSpec":true,"requiresPFrame":true,"requiresDialog":true}},"timestamp":1784886716922,"files":[{"name":"main.plj.gz","size":1128560,"sha256":"CA17476183C0D51590FBFE8F8F4BAB50F6A86BC50A6D267FBA144149F4F3E257"},{"name":"model.json","size":453138,"sha256":"DB592BE6272DE5EEB238E3AA7B3633F8D809F82D2BD3D5B5437E0D762343B447"},{"name":"ui.tgz","size":6638692,"sha256":"027646F471C383AD3E2EF0D74F0E006077028E245E9A4A1DDABA5211F48D49CA"},{"name":"organization-logo.png","size":24439,"sha256":"FA71390C77C91E4B7FAAE5640D00F92F1E3F2869296F68B6040DD7CC549A50B5"},{"name":"description.md","size":2837,"sha256":"7180D87812D1EDB72B6EE70944412511F075EF8D1186946EE976383800898647"},{"name":"CHANGELOG.md","size":27,"sha256":"3E1D1DA422E5D609FCDE7F996A81F7635011F3CA297923598DB36D924C4A0DAE"},{"name":"block-logo.png","size":21527,"sha256":"6BB33BAF0CD039549661B51AE490373BE60D1811EC71F5023400928293BC2427"}]}