@platforma-open/milaboratories.sort-seq-analysis.block 1.0.2 → 1.0.3
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/block-pack/CHANGELOG.md +26 -0
- package/block-pack/description.md +0 -9
- package/block-pack/main.plj.gz +0 -0
- package/block-pack/manifest.json +1 -1
- package/block-pack/model.json +1 -1
- package/block-pack/published.json +1 -1
- package/block-pack/ui.tgz +0 -0
- package/dist/AGENTS.d.ts +11 -2
- package/dist/AGENTS.d.ts.map +1 -1
- package/dist/index.d.ts +11 -2
- package/dist/index.d.ts.map +1 -1
- package/dist/index.js +1 -2
- package/dist/index.js.map +1 -1
- package/package.json +4 -4
package/block-pack/CHANGELOG.md
CHANGED
|
@@ -1,5 +1,31 @@
|
|
|
1
1
|
# @platforma-open/milaboratories.sort-seq-analysis.block
|
|
2
2
|
|
|
3
|
+
## 1.0.3
|
|
4
|
+
|
|
5
|
+
### Patch Changes
|
|
6
|
+
|
|
7
|
+
- 97db2d1: Gate order is a selection, not a ranking of every value the gate column carries
|
|
8
|
+
|
|
9
|
+
The block no longer refuses to run until every distinct value of the gate column has been
|
|
10
|
+
given an order position. The gate column of a real sort-seq run routinely carries values
|
|
11
|
+
that are not rungs on the binding ladder — an unsorted input, a specificity arm, a
|
|
12
|
+
stability arm — and demanding a rank for each refused configurations the computation runs
|
|
13
|
+
perfectly well.
|
|
14
|
+
|
|
15
|
+
The ordered list is now the run's gate scope: the gates it holds, in the order it holds
|
|
16
|
+
them, are the ladder, and removing a value takes it and its samples out of the run. Ranks
|
|
17
|
+
stay contiguous from 1 over the gates that remain, so a removal leaves no gap that would
|
|
18
|
+
shift every score.
|
|
19
|
+
|
|
20
|
+
- **Model** — the coverage check is gone; what remains is that the list is non-empty and
|
|
21
|
+
names nothing the column does not carry.
|
|
22
|
+
- **Computation** — rows outside the declared ladder are dropped before the depths are
|
|
23
|
+
taken, so an unselected gate contributes to neither sum of the weighted mean. Its
|
|
24
|
+
samples are likewise outside the one-sample-per-group and sort-fraction refusals, and
|
|
25
|
+
its fraction is not part of a condition's sum.
|
|
26
|
+
- **A condition whose every sample sits in an unselected gate** is dropped from the run,
|
|
27
|
+
exactly as an excluded condition is, rather than scored to an empty file.
|
|
28
|
+
|
|
3
29
|
## 1.0.2
|
|
4
30
|
|
|
5
31
|
### Patch Changes
|
|
@@ -16,12 +16,3 @@ A run over N conditions emits both quantities N times, once per condition. A one
|
|
|
16
16
|
ordinary run: it gets both quantities, with the run's single condition on each column exactly as a
|
|
17
17
|
two-condition run would carry two.
|
|
18
18
|
|
|
19
|
-
## Downstream
|
|
20
|
-
|
|
21
|
-
Everything downstream of this block is a comparison of these scores — a pH switch is the difference between
|
|
22
|
-
a variant's bin score at two pH arms, the on-state is its raw score at the arm the campaign treats as *on*,
|
|
23
|
-
and a shortlist is a ranking over one of them.
|
|
24
|
-
|
|
25
|
-
## Status
|
|
26
|
-
|
|
27
|
-
Under development. The specification lives in `docs/text/work/projects/sequence-repertoires/facs-bin-analysis/`.
|
package/block-pack/main.plj.gz
CHANGED
|
Binary file
|
package/block-pack/manifest.json
CHANGED
|
@@ -1 +1 @@
|
|
|
1
|
-
{"schema":"v2","description":{"id":{"organization":"milaboratories","name":"sort-seq-analysis","version":"1.0.
|
|
1
|
+
{"schema":"v2","description":{"id":{"organization":"milaboratories","name":"sort-seq-analysis","version":"1.0.3"},"components":{"workflow":{"type":"workflow-v1","main":{"type":"relative","path":"main.plj.gz"}},"model":{"type":"relative","path":"model.json"},"ui":{"type":"relative","path":"ui.tgz"}},"meta":{"title":"Sort-Seq Analysis","description":"Scores protein variants from a sort-seq (FACS bin) experiment: per condition, the read-weighted mean of the gate ranks each variant sorted into, and that value minus the parent's.","longDescription":{"type":"relative","path":"description.md"},"changelog":{"type":"relative","path":"CHANGELOG.md"},"logo":{"type":"relative","path":"block-logo.png"},"url":"https://github.com/platforma-open/sort-seq-analysis","support":"mailto:support@milaboratories.com","tags":["downstream","dms","antibody","assay"],"organization":{"name":"MiLaboratories Inc","url":"https://milaboratories.com/","logo":{"type":"relative","path":"organization-logo.png"}}},"featureFlags":{"supportsLazyState":true,"supportsPframeQueryRanking":true,"requiresUIAPIVersion":3,"requiresModelAPIVersion":2,"requiresCreatePTable":2,"requiresPFramesVersion":1001031,"requiresPFrameSpec":true,"requiresPFrame":true,"requiresDialog":true,"requiresColumnsCollection":true}},"timestamp":1786638913022,"files":[{"name":"main.plj.gz","size":798299,"sha256":"371DA479E26813954851C47E449020290FE6107A05CD7B7BB6375C2C2F68266A"},{"name":"model.json","size":516654,"sha256":"8B459D1E60763AEB91359132D1CF1740423CA081C0A07FF5C6D6CC3A5EA7359C"},{"name":"ui.tgz","size":6343424,"sha256":"AC3A479CC01B55F47ACA2A068B9261DFBC8EE0E755B7734057A1D5F5139D7C76"},{"name":"organization-logo.png","size":21527,"sha256":"6BB33BAF0CD039549661B51AE490373BE60D1811EC71F5023400928293BC2427"},{"name":"description.md","size":1035,"sha256":"49CEBEA9C9B395A12ECC5D1FF7CDEE9E6BA371C5D4E6E7FA874C07A3DC1AB3E1"},{"name":"CHANGELOG.md","size":2752,"sha256":"2AFD1E18D18F7CF5E30158CA300C337BEC28949280EA518180F161C3557A42B1"},{"name":"block-logo.png","size":21527,"sha256":"6BB33BAF0CD039549661B51AE490373BE60D1811EC71F5023400928293BC2427"}]}
|