@platforma-open/milaboratories.mixcr-clonotyping-2 2.19.0 → 2.20.0

package/block-pack/description.md

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+# Overview
+
+This block analyzes sequencing data to identify and quantify the T-cell and B-cell receptor clonotypes in your samples. It is a crucial first step for many immunology studies, allowing to explore the diversity and composition of the adaptive immune system.
+
+The block takes raw sequencing data (bulk, single cell, RNA-Seq, Sanger etc.) and uses the MiXCR tool to perform V(D)J clonotyping, which involves alignment, error correction, assembling the receptor gene sequences and grouping them into clonotypes.
+
+The outputs dataset can then be used in downstream blocks for deeper analysis, such as comparing clonality metrics between sample groups, tracking clonotypes over time, or building a TCR/antibody lead list.
+
+MiXCR is developed by MiLaboratories Inc. For more information, please see the [MiXCR website](https://mixcr.com/) and cite the following publication if you use this block in your research:
+
+> Bolotin, D., Poslavsky, S., Mitrophanov, I. et al. MiXCR: software for comprehensive adaptive immunity profiling. _Nat Methods_ **12**, 380–381 (2015) [https://doi.org/10.1038/nmeth.3364](https://doi.org/10.1038/nmeth.3364)

package/block-pack/manifest.json

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