@platforma-open/milaboratories.clonotype-clustering 3.2.0 → 3.2.2

package/block-pack/CHANGELOG.md

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+## 1.0.0
+
+Initial release.

package/block-pack/description.md

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+# Overview
+
+Groups similar sequences — clonotypes or peptides — into clusters based on sequence similarity, enabling researchers to identify related sequences that may share functional properties or antigen specificities. The block uses MMseqs2's clustering algorithms (Easy Cluster or Easy Linclust) for fast and sensitive sequence searching, grouping sequences that meet a specified identity threshold. Clustering runs on amino acid or nucleotide sequences (configurable), and results include cluster assignments for each sequence along with cluster-level statistics, visualized using bubble plots and histograms.
+
+The clustered data can be used in downstream analysis blocks such as Sequence Enrichment to analyze enrichment patterns at the cluster level across selection rounds, or Lead Selection to identify top candidates based on cluster-level scoring metrics.
+
+MMseqs2 is developed by the Söding lab and Steinegger group. For more information, please see: [https://github.com/soedinglab/MMseqs2](https://github.com/soedinglab/MMseqs2) and cite the following publication if used in your research:
+
+> Steinegger M and Soeding J. MMseqs2 enables sensitive protein sequence searching for the analysis of massive data sets. _Nature Biotechnology_, doi: 10.1038/nbt.3988 (2017). [https://doi.org/10.1038/nbt.3988](https://doi.org/10.1038/nbt.3988)

package/block-pack/manifest.json

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