@pharmatools/pubcrawl 2.0.0 → 2.1.1

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (23) hide show
  1. package/README.md +37 -11
  2. package/dist/index.js +4 -0
  3. package/dist/index.js.map +1 -1
  4. package/dist/lib/cache.d.ts +1 -0
  5. package/dist/lib/cache.d.ts.map +1 -1
  6. package/dist/lib/cache.js +2 -0
  7. package/dist/lib/cache.js.map +1 -1
  8. package/dist/lib/clinicaltrials.d.ts +15 -0
  9. package/dist/lib/clinicaltrials.d.ts.map +1 -0
  10. package/dist/lib/clinicaltrials.js +213 -0
  11. package/dist/lib/clinicaltrials.js.map +1 -0
  12. package/dist/tools/trials-detail.d.ts +3 -0
  13. package/dist/tools/trials-detail.d.ts.map +1 -0
  14. package/dist/tools/trials-detail.js +38 -0
  15. package/dist/tools/trials-detail.js.map +1 -0
  16. package/dist/tools/trials-search.d.ts +3 -0
  17. package/dist/tools/trials-search.d.ts.map +1 -0
  18. package/dist/tools/trials-search.js +66 -0
  19. package/dist/tools/trials-search.js.map +1 -0
  20. package/dist/types.d.ts +55 -0
  21. package/dist/types.d.ts.map +1 -1
  22. package/package.json +1 -1
  23. package/server.json +1 -1
package/README.md CHANGED
@@ -1,6 +1,6 @@
1
1
  # PubCrawl
2
2
 
3
- An [MCP server](https://modelcontextprotocol.io) that gives LLM clients access to PubMed, FDA drug labelling, and UK medicines data. A peer-reviewed pub crawl through the literature — and the label.
3
+ An [MCP server](https://modelcontextprotocol.io) that gives LLM clients access to PubMed, FDA drug labelling, UK medicines data, and ClinicalTrials.gov. A peer-reviewed pub crawl through the literature — the label — and the trial.
4
4
 
5
5
  Built by [PharmaTools.AI](https://pharmatools.ai).
6
6
 
@@ -26,20 +26,24 @@ Built by [PharmaTools.AI](https://pharmatools.ai).
26
26
  | `compare_labels` | Side-by-side comparison of US (USPI) and UK (SmPC) labelling for the same drug. Spot regulatory differences in indications, warnings, and dosing. |
27
27
  | `search_by_indication` | Find drugs approved for a medical condition. Searches FDA labelling via OpenFDA, then cross-references UK availability on the eMC. |
28
28
 
29
+ ### Clinical Trials
30
+
31
+ | Tool | What it does |
32
+ |------|-------------|
33
+ | `search_trials` | Search ClinicalTrials.gov for clinical trials. Filter by condition, intervention, recruitment status, and phase. Returns NCT IDs, sponsors, enrollment, and links. |
34
+ | `get_trial` | Get full details for a clinical trial by NCT ID — eligibility criteria, study design, arms, primary/secondary outcomes, locations, and associated PubMed IDs. |
35
+
29
36
  ## Setup
30
37
 
31
38
  ### Prerequisites
32
39
 
33
- - Node.js 18+
40
+ - Node.js 20+
34
41
  - An MCP-compatible client (Claude Desktop, Cursor, etc.)
35
42
 
36
- ### Install and build
43
+ ### Install via npm
37
44
 
38
45
  ```bash
39
- git clone https://github.com/nickjlamb/pubcrawl.git
40
- cd pubcrawl
41
- npm install
42
- npm run build
46
+ npm install -g @pharmatools/pubcrawl
43
47
  ```
44
48
 
45
49
  ### Configure Claude Desktop
@@ -53,8 +57,7 @@ Add to your `claude_desktop_config.json`:
53
57
  {
54
58
  "mcpServers": {
55
59
  "pubcrawl": {
56
- "command": "node",
57
- "args": ["/path/to/pubcrawl/dist/index.js"]
60
+ "command": "pubcrawl"
58
61
  }
59
62
  }
60
63
  }
@@ -62,6 +65,28 @@ Add to your `claude_desktop_config.json`:
62
65
 
63
66
  Restart Claude Desktop. PubCrawl will appear under **+ → Connectors**.
64
67
 
68
+ ### Install from source
69
+
70
+ ```bash
71
+ git clone https://github.com/nickjlamb/pubcrawl.git
72
+ cd pubcrawl
73
+ npm install
74
+ npm run build
75
+ ```
76
+
77
+ Then point the config at the built file:
78
+
79
+ ```json
80
+ {
81
+ "mcpServers": {
82
+ "pubcrawl": {
83
+ "command": "node",
84
+ "args": ["/path/to/pubcrawl/dist/index.js"]
85
+ }
86
+ }
87
+ }
88
+ ```
89
+
65
90
  ### NCBI API key (optional)
66
91
 
67
92
  Without an API key, requests are rate-limited to 3/second. With one, you get 10/second.
@@ -74,8 +99,7 @@ Without an API key, requests are rate-limited to 3/second. With one, you get 10/
74
99
  {
75
100
  "mcpServers": {
76
101
  "pubcrawl": {
77
- "command": "node",
78
- "args": ["/path/to/pubcrawl/dist/index.js"],
102
+ "command": "pubcrawl",
79
103
  "env": {
80
104
  "NCBI_API_KEY": "your_key_here"
81
105
  }
@@ -97,6 +121,8 @@ Once connected, just ask naturally:
97
121
  - "Pull the UK SmPC for atorvastatin"
98
122
  - "Compare US and UK labelling for lisinopril"
99
123
  - "What drugs are approved for type 2 diabetes?"
124
+ - "Find recruiting Phase 3 trials for pembrolizumab in breast cancer"
125
+ - "Get details on clinical trial NCT03086486"
100
126
 
101
127
  ## Development
102
128
 
package/dist/index.js CHANGED
@@ -13,6 +13,8 @@ import { registerUspiTool } from "./tools/uspi.js";
13
13
  import { registerSmpcTool } from "./tools/smpc.js";
14
14
  import { registerCompareLabelsTool } from "./tools/compare-labels.js";
15
15
  import { registerSearchIndicationTool } from "./tools/search-indication.js";
16
+ import { registerTrialsSearchTool } from "./tools/trials-search.js";
17
+ import { registerTrialDetailTool } from "./tools/trials-detail.js";
16
18
  const server = new McpServer({
17
19
  name: "pubcrawl",
18
20
  version: "2.0.0",
@@ -32,6 +34,8 @@ registerUspiTool(server);
32
34
  registerSmpcTool(server);
33
35
  registerCompareLabelsTool(server);
34
36
  registerSearchIndicationTool(server);
37
+ registerTrialsSearchTool(server);
38
+ registerTrialDetailTool(server);
35
39
  // Start server
36
40
  async function main() {
37
41
  const transport = new StdioServerTransport();
package/dist/index.js.map CHANGED
@@ -1 +1 @@
1
- {"version":3,"file":"index.js","sourceRoot":"","sources":["../src/index.ts"],"names":[],"mappings":";AACA,OAAO,eAAe,CAAC;AACvB,OAAO,EAAE,SAAS,EAAE,MAAM,yCAAyC,CAAC;AACpE,OAAO,EAAE,oBAAoB,EAAE,MAAM,2CAA2C,CAAC;AACjF,OAAO,EAAE,SAAS,EAAE,MAAM,eAAe,CAAC;AAC1C,OAAO,EAAE,kBAAkB,EAAE,MAAM,mBAAmB,CAAC;AACvD,OAAO,EAAE,oBAAoB,EAAE,MAAM,qBAAqB,CAAC;AAC3D,OAAO,EAAE,oBAAoB,EAAE,MAAM,qBAAqB,CAAC;AAC3D,OAAO,EAAE,mBAAmB,EAAE,MAAM,oBAAoB,CAAC;AACzD,OAAO,EAAE,gBAAgB,EAAE,MAAM,iBAAiB,CAAC;AACnD,OAAO,EAAE,oBAAoB,EAAE,MAAM,qBAAqB,CAAC;AAC3D,OAAO,EAAE,gBAAgB,EAAE,MAAM,iBAAiB,CAAC;AACnD,OAAO,EAAE,gBAAgB,EAAE,MAAM,iBAAiB,CAAC;AACnD,OAAO,EAAE,yBAAyB,EAAE,MAAM,2BAA2B,CAAC;AACtE,OAAO,EAAE,4BAA4B,EAAE,MAAM,8BAA8B,CAAC;AAE5E,MAAM,MAAM,GAAG,IAAI,SAAS,CAAC;IAC3B,IAAI,EAAE,UAAU;IAChB,OAAO,EAAE,OAAO;CACjB,CAAC,CAAC;AAEH,4DAA4D;AAC5D,IAAI,OAAO,CAAC,GAAG,CAAC,YAAY,EAAE,CAAC;IAC7B,SAAS,CAAC,OAAO,CAAC,GAAG,CAAC,YAAY,CAAC,CAAC;AACtC,CAAC;AAED,qBAAqB;AACrB,kBAAkB,CAAC,MAAM,CAAC,CAAC;AAC3B,oBAAoB,CAAC,MAAM,CAAC,CAAC;AAC7B,oBAAoB,CAAC,MAAM,CAAC,CAAC;AAC7B,mBAAmB,CAAC,MAAM,CAAC,CAAC;AAC5B,gBAAgB,CAAC,MAAM,CAAC,CAAC;AACzB,oBAAoB,CAAC,MAAM,CAAC,CAAC;AAC7B,gBAAgB,CAAC,MAAM,CAAC,CAAC;AACzB,gBAAgB,CAAC,MAAM,CAAC,CAAC;AACzB,yBAAyB,CAAC,MAAM,CAAC,CAAC;AAClC,4BAA4B,CAAC,MAAM,CAAC,CAAC;AAErC,eAAe;AACf,KAAK,UAAU,IAAI;IACjB,MAAM,SAAS,GAAG,IAAI,oBAAoB,EAAE,CAAC;IAC7C,MAAM,MAAM,CAAC,OAAO,CAAC,SAAS,CAAC,CAAC;IAChC,OAAO,CAAC,KAAK,CAAC,sCAAsC,CAAC,CAAC;AACxD,CAAC;AAED,IAAI,EAAE,CAAC,KAAK,CAAC,CAAC,KAAK,EAAE,EAAE;IACrB,OAAO,CAAC,KAAK,CAAC,cAAc,EAAE,KAAK,CAAC,CAAC;IACrC,OAAO,CAAC,IAAI,CAAC,CAAC,CAAC,CAAC;AAClB,CAAC,CAAC,CAAC"}
1
+ {"version":3,"file":"index.js","sourceRoot":"","sources":["../src/index.ts"],"names":[],"mappings":";AACA,OAAO,eAAe,CAAC;AACvB,OAAO,EAAE,SAAS,EAAE,MAAM,yCAAyC,CAAC;AACpE,OAAO,EAAE,oBAAoB,EAAE,MAAM,2CAA2C,CAAC;AACjF,OAAO,EAAE,SAAS,EAAE,MAAM,eAAe,CAAC;AAC1C,OAAO,EAAE,kBAAkB,EAAE,MAAM,mBAAmB,CAAC;AACvD,OAAO,EAAE,oBAAoB,EAAE,MAAM,qBAAqB,CAAC;AAC3D,OAAO,EAAE,oBAAoB,EAAE,MAAM,qBAAqB,CAAC;AAC3D,OAAO,EAAE,mBAAmB,EAAE,MAAM,oBAAoB,CAAC;AACzD,OAAO,EAAE,gBAAgB,EAAE,MAAM,iBAAiB,CAAC;AACnD,OAAO,EAAE,oBAAoB,EAAE,MAAM,qBAAqB,CAAC;AAC3D,OAAO,EAAE,gBAAgB,EAAE,MAAM,iBAAiB,CAAC;AACnD,OAAO,EAAE,gBAAgB,EAAE,MAAM,iBAAiB,CAAC;AACnD,OAAO,EAAE,yBAAyB,EAAE,MAAM,2BAA2B,CAAC;AACtE,OAAO,EAAE,4BAA4B,EAAE,MAAM,8BAA8B,CAAC;AAC5E,OAAO,EAAE,wBAAwB,EAAE,MAAM,0BAA0B,CAAC;AACpE,OAAO,EAAE,uBAAuB,EAAE,MAAM,0BAA0B,CAAC;AAEnE,MAAM,MAAM,GAAG,IAAI,SAAS,CAAC;IAC3B,IAAI,EAAE,UAAU;IAChB,OAAO,EAAE,OAAO;CACjB,CAAC,CAAC;AAEH,4DAA4D;AAC5D,IAAI,OAAO,CAAC,GAAG,CAAC,YAAY,EAAE,CAAC;IAC7B,SAAS,CAAC,OAAO,CAAC,GAAG,CAAC,YAAY,CAAC,CAAC;AACtC,CAAC;AAED,qBAAqB;AACrB,kBAAkB,CAAC,MAAM,CAAC,CAAC;AAC3B,oBAAoB,CAAC,MAAM,CAAC,CAAC;AAC7B,oBAAoB,CAAC,MAAM,CAAC,CAAC;AAC7B,mBAAmB,CAAC,MAAM,CAAC,CAAC;AAC5B,gBAAgB,CAAC,MAAM,CAAC,CAAC;AACzB,oBAAoB,CAAC,MAAM,CAAC,CAAC;AAC7B,gBAAgB,CAAC,MAAM,CAAC,CAAC;AACzB,gBAAgB,CAAC,MAAM,CAAC,CAAC;AACzB,yBAAyB,CAAC,MAAM,CAAC,CAAC;AAClC,4BAA4B,CAAC,MAAM,CAAC,CAAC;AACrC,wBAAwB,CAAC,MAAM,CAAC,CAAC;AACjC,uBAAuB,CAAC,MAAM,CAAC,CAAC;AAEhC,eAAe;AACf,KAAK,UAAU,IAAI;IACjB,MAAM,SAAS,GAAG,IAAI,oBAAoB,EAAE,CAAC;IAC7C,MAAM,MAAM,CAAC,OAAO,CAAC,SAAS,CAAC,CAAC;IAChC,OAAO,CAAC,KAAK,CAAC,sCAAsC,CAAC,CAAC;AACxD,CAAC;AAED,IAAI,EAAE,CAAC,KAAK,CAAC,CAAC,KAAK,EAAE,EAAE;IACrB,OAAO,CAAC,KAAK,CAAC,cAAc,EAAE,KAAK,CAAC,CAAC;IACrC,OAAO,CAAC,IAAI,CAAC,CAAC,CAAC,CAAC;AAClB,CAAC,CAAC,CAAC"}
package/dist/lib/cache.d.ts CHANGED
@@ -5,6 +5,7 @@ export declare const TTL: {
5
5
  readonly RELATED: number;
6
6
  readonly SUMMARY: number;
7
7
  readonly LABEL: number;
8
+ readonly TRIAL: number;
8
9
  };
9
10
  export declare class LRUCache {
10
11
  private cache;
package/dist/lib/cache.d.ts.map CHANGED
@@ -1 +1 @@
1
- {"version":3,"file":"cache.d.ts","sourceRoot":"","sources":["../../src/lib/cache.ts"],"names":[],"mappings":"AAMA,eAAO,MAAM,GAAG;;;;;;;CAON,CAAC;AAEX,qBAAa,QAAQ;IACnB,OAAO,CAAC,KAAK,CAA0C;IACvD,OAAO,CAAC,UAAU,CAAS;gBAEf,UAAU,SAAsB;IAI5C,GAAG,CAAC,CAAC,EAAE,GAAG,EAAE,MAAM,GAAG,CAAC,GAAG,SAAS;IAelC,GAAG,CAAC,CAAC,EAAE,GAAG,EAAE,MAAM,EAAE,KAAK,EAAE,CAAC,EAAE,GAAG,EAAE,MAAM,GAAG,IAAI;IAgBhD,KAAK,IAAI,IAAI;IAIb,IAAI,IAAI,IAAI,MAAM,CAEjB;CACF;AAED,eAAO,MAAM,KAAK,UAAiB,CAAC"}
1
+ {"version":3,"file":"cache.d.ts","sourceRoot":"","sources":["../../src/lib/cache.ts"],"names":[],"mappings":"AAOA,eAAO,MAAM,GAAG;;;;;;;;CAQN,CAAC;AAEX,qBAAa,QAAQ;IACnB,OAAO,CAAC,KAAK,CAA0C;IACvD,OAAO,CAAC,UAAU,CAAS;gBAEf,UAAU,SAAsB;IAI5C,GAAG,CAAC,CAAC,EAAE,GAAG,EAAE,MAAM,GAAG,CAAC,GAAG,SAAS;IAelC,GAAG,CAAC,CAAC,EAAE,GAAG,EAAE,MAAM,EAAE,KAAK,EAAE,CAAC,EAAE,GAAG,EAAE,MAAM,GAAG,IAAI;IAgBhD,KAAK,IAAI,IAAI;IAIb,IAAI,IAAI,IAAI,MAAM,CAEjB;CACF;AAED,eAAO,MAAM,KAAK,UAAiB,CAAC"}
package/dist/lib/cache.js CHANGED
@@ -1,5 +1,6 @@
1
1
  const DEFAULT_MAX_ENTRIES = 500;
2
2
  const ONE_HOUR_MS = 60 * 60 * 1000;
3
+ const FOUR_HOURS_MS = 4 * 60 * 60 * 1000;
3
4
  const ONE_DAY_MS = 24 * 60 * 60 * 1000;
4
5
  export const TTL = {
5
6
  SEARCH: ONE_HOUR_MS,
@@ -8,6 +9,7 @@ export const TTL = {
8
9
  RELATED: ONE_HOUR_MS,
9
10
  SUMMARY: ONE_HOUR_MS,
10
11
  LABEL: ONE_DAY_MS,
12
+ TRIAL: FOUR_HOURS_MS,
11
13
  };
12
14
  export class LRUCache {
13
15
  cache = new Map();
package/dist/lib/cache.js.map CHANGED
@@ -1 +1 @@
1
- {"version":3,"file":"cache.js","sourceRoot":"","sources":["../../src/lib/cache.ts"],"names":[],"mappings":"AAEA,MAAM,mBAAmB,GAAG,GAAG,CAAC;AAChC,MAAM,WAAW,GAAG,EAAE,GAAG,EAAE,GAAG,IAAI,CAAC;AACnC,MAAM,UAAU,GAAG,EAAE,GAAG,EAAE,GAAG,EAAE,GAAG,IAAI,CAAC;AAEvC,MAAM,CAAC,MAAM,GAAG,GAAG;IACjB,MAAM,EAAE,WAAW;IACnB,QAAQ,EAAE,UAAU;IACpB,QAAQ,EAAE,UAAU;IACpB,OAAO,EAAE,WAAW;IACpB,OAAO,EAAE,WAAW;IACpB,KAAK,EAAE,UAAU;CACT,CAAC;AAEX,MAAM,OAAO,QAAQ;IACX,KAAK,GAAG,IAAI,GAAG,EAA+B,CAAC;IAC/C,UAAU,CAAS;IAE3B,YAAY,UAAU,GAAG,mBAAmB;QAC1C,IAAI,CAAC,UAAU,GAAG,UAAU,CAAC;IAC/B,CAAC;IAED,GAAG,CAAI,GAAW;QAChB,MAAM,KAAK,GAAG,IAAI,CAAC,KAAK,CAAC,GAAG,CAAC,GAAG,CAAC,CAAC;QAClC,IAAI,CAAC,KAAK;YAAE,OAAO,SAAS,CAAC;QAE7B,IAAI,IAAI,CAAC,GAAG,EAAE,GAAG,KAAK,CAAC,SAAS,GAAG,KAAK,CAAC,GAAG,EAAE,CAAC;YAC7C,IAAI,CAAC,KAAK,CAAC,MAAM,CAAC,GAAG,CAAC,CAAC;YACvB,OAAO,SAAS,CAAC;QACnB,CAAC;QAED,mCAAmC;QACnC,IAAI,CAAC,KAAK,CAAC,MAAM,CAAC,GAAG,CAAC,CAAC;QACvB,IAAI,CAAC,KAAK,CAAC,GAAG,CAAC,GAAG,EAAE,KAAK,CAAC,CAAC;QAC3B,OAAO,KAAK,CAAC,KAAU,CAAC;IAC1B,CAAC;IAED,GAAG,CAAI,GAAW,EAAE,KAAQ,EAAE,GAAW;QACvC,IAAI,IAAI,CAAC,KAAK,CAAC,GAAG,CAAC,GAAG,CAAC,EAAE,CAAC;YACxB,IAAI,CAAC,KAAK,CAAC,MAAM,CAAC,GAAG,CAAC,CAAC;QACzB,CAAC;QAED,IAAI,IAAI,CAAC,KAAK,CAAC,IAAI,IAAI,IAAI,CAAC,UAAU,EAAE,CAAC;YACvC,0CAA0C;YAC1C,MAAM,QAAQ,GAAG,IAAI,CAAC,KAAK,CAAC,IAAI,EAAE,CAAC,IAAI,EAAE,CAAC,KAAK,CAAC;YAChD,IAAI,QAAQ,KAAK,SAAS,EAAE,CAAC;gBAC3B,IAAI,CAAC,KAAK,CAAC,MAAM,CAAC,QAAQ,CAAC,CAAC;YAC9B,CAAC;QACH,CAAC;QAED,IAAI,CAAC,KAAK,CAAC,GAAG,CAAC,GAAG,EAAE,EAAE,KAAK,EAAE,SAAS,EAAE,IAAI,CAAC,GAAG,EAAE,EAAE,GAAG,EAAE,CAAC,CAAC;IAC7D,CAAC;IAED,KAAK;QACH,IAAI,CAAC,KAAK,CAAC,KAAK,EAAE,CAAC;IACrB,CAAC;IAED,IAAI,IAAI;QACN,OAAO,IAAI,CAAC,KAAK,CAAC,IAAI,CAAC;IACzB,CAAC;CACF;AAED,MAAM,CAAC,MAAM,KAAK,GAAG,IAAI,QAAQ,EAAE,CAAC"}
1
+ {"version":3,"file":"cache.js","sourceRoot":"","sources":["../../src/lib/cache.ts"],"names":[],"mappings":"AAEA,MAAM,mBAAmB,GAAG,GAAG,CAAC;AAChC,MAAM,WAAW,GAAG,EAAE,GAAG,EAAE,GAAG,IAAI,CAAC;AACnC,MAAM,aAAa,GAAG,CAAC,GAAG,EAAE,GAAG,EAAE,GAAG,IAAI,CAAC;AACzC,MAAM,UAAU,GAAG,EAAE,GAAG,EAAE,GAAG,EAAE,GAAG,IAAI,CAAC;AAEvC,MAAM,CAAC,MAAM,GAAG,GAAG;IACjB,MAAM,EAAE,WAAW;IACnB,QAAQ,EAAE,UAAU;IACpB,QAAQ,EAAE,UAAU;IACpB,OAAO,EAAE,WAAW;IACpB,OAAO,EAAE,WAAW;IACpB,KAAK,EAAE,UAAU;IACjB,KAAK,EAAE,aAAa;CACZ,CAAC;AAEX,MAAM,OAAO,QAAQ;IACX,KAAK,GAAG,IAAI,GAAG,EAA+B,CAAC;IAC/C,UAAU,CAAS;IAE3B,YAAY,UAAU,GAAG,mBAAmB;QAC1C,IAAI,CAAC,UAAU,GAAG,UAAU,CAAC;IAC/B,CAAC;IAED,GAAG,CAAI,GAAW;QAChB,MAAM,KAAK,GAAG,IAAI,CAAC,KAAK,CAAC,GAAG,CAAC,GAAG,CAAC,CAAC;QAClC,IAAI,CAAC,KAAK;YAAE,OAAO,SAAS,CAAC;QAE7B,IAAI,IAAI,CAAC,GAAG,EAAE,GAAG,KAAK,CAAC,SAAS,GAAG,KAAK,CAAC,GAAG,EAAE,CAAC;YAC7C,IAAI,CAAC,KAAK,CAAC,MAAM,CAAC,GAAG,CAAC,CAAC;YACvB,OAAO,SAAS,CAAC;QACnB,CAAC;QAED,mCAAmC;QACnC,IAAI,CAAC,KAAK,CAAC,MAAM,CAAC,GAAG,CAAC,CAAC;QACvB,IAAI,CAAC,KAAK,CAAC,GAAG,CAAC,GAAG,EAAE,KAAK,CAAC,CAAC;QAC3B,OAAO,KAAK,CAAC,KAAU,CAAC;IAC1B,CAAC;IAED,GAAG,CAAI,GAAW,EAAE,KAAQ,EAAE,GAAW;QACvC,IAAI,IAAI,CAAC,KAAK,CAAC,GAAG,CAAC,GAAG,CAAC,EAAE,CAAC;YACxB,IAAI,CAAC,KAAK,CAAC,MAAM,CAAC,GAAG,CAAC,CAAC;QACzB,CAAC;QAED,IAAI,IAAI,CAAC,KAAK,CAAC,IAAI,IAAI,IAAI,CAAC,UAAU,EAAE,CAAC;YACvC,0CAA0C;YAC1C,MAAM,QAAQ,GAAG,IAAI,CAAC,KAAK,CAAC,IAAI,EAAE,CAAC,IAAI,EAAE,CAAC,KAAK,CAAC;YAChD,IAAI,QAAQ,KAAK,SAAS,EAAE,CAAC;gBAC3B,IAAI,CAAC,KAAK,CAAC,MAAM,CAAC,QAAQ,CAAC,CAAC;YAC9B,CAAC;QACH,CAAC;QAED,IAAI,CAAC,KAAK,CAAC,GAAG,CAAC,GAAG,EAAE,EAAE,KAAK,EAAE,SAAS,EAAE,IAAI,CAAC,GAAG,EAAE,EAAE,GAAG,EAAE,CAAC,CAAC;IAC7D,CAAC;IAED,KAAK;QACH,IAAI,CAAC,KAAK,CAAC,KAAK,EAAE,CAAC;IACrB,CAAC;IAED,IAAI,IAAI;QACN,OAAO,IAAI,CAAC,KAAK,CAAC,IAAI,CAAC;IACzB,CAAC;CACF;AAED,MAAM,CAAC,MAAM,KAAK,GAAG,IAAI,QAAQ,EAAE,CAAC"}
package/dist/lib/clinicaltrials.d.ts ADDED
@@ -0,0 +1,15 @@
1
+ import { ClinicalTrialSummary, ClinicalTrialDetail } from "../types.js";
2
+ export declare function searchTrials(params: {
3
+ condition?: string;
4
+ intervention?: string;
5
+ term?: string;
6
+ status?: string;
7
+ phase?: string;
8
+ maxResults?: number;
9
+ sort?: string;
10
+ }): Promise<{
11
+ results: ClinicalTrialSummary[];
12
+ total_count: number;
13
+ }>;
14
+ export declare function getTrialDetail(nctId: string): Promise<ClinicalTrialDetail>;
15
+ //# sourceMappingURL=clinicaltrials.d.ts.map
package/dist/lib/clinicaltrials.d.ts.map ADDED
@@ -0,0 +1 @@
1
+ {"version":3,"file":"clinicaltrials.d.ts","sourceRoot":"","sources":["../../src/lib/clinicaltrials.ts"],"names":[],"mappings":"AACA,OAAO,EACL,oBAAoB,EACpB,mBAAmB,EAKpB,MAAM,aAAa,CAAC;AA6FrB,wBAAsB,YAAY,CAAC,MAAM,EAAE;IACzC,SAAS,CAAC,EAAE,MAAM,CAAC;IACnB,YAAY,CAAC,EAAE,MAAM,CAAC;IACtB,IAAI,CAAC,EAAE,MAAM,CAAC;IACd,MAAM,CAAC,EAAE,MAAM,CAAC;IAChB,KAAK,CAAC,EAAE,MAAM,CAAC;IACf,UAAU,CAAC,EAAE,MAAM,CAAC;IACpB,IAAI,CAAC,EAAE,MAAM,CAAC;CACf,GAAG,OAAO,CAAC;IAAE,OAAO,EAAE,oBAAoB,EAAE,CAAC;IAAC,WAAW,EAAE,MAAM,CAAA;CAAE,CAAC,CA2DpE;AAED,wBAAsB,cAAc,CAAC,KAAK,EAAE,MAAM,GAAG,OAAO,CAAC,mBAAmB,CAAC,CA0FhF"}
package/dist/lib/clinicaltrials.js ADDED
@@ -0,0 +1,213 @@
1
+ import { cache, TTL } from "./cache.js";
2
+ const BASE_URL = "https://clinicaltrials.gov/api/v2";
3
+ const REQUEST_DELAY_MS = 1200; // ~50 req/min
4
+ const TIMEOUT_MS = 15000;
5
+ let lastRequestTime = 0;
6
+ async function rateLimitedFetch(url) {
7
+ const now = Date.now();
8
+ const elapsed = now - lastRequestTime;
9
+ if (elapsed < REQUEST_DELAY_MS) {
10
+ await new Promise((resolve) => setTimeout(resolve, REQUEST_DELAY_MS - elapsed));
11
+ }
12
+ lastRequestTime = Date.now();
13
+ const controller = new AbortController();
14
+ const timeout = setTimeout(() => controller.abort(), TIMEOUT_MS);
15
+ try {
16
+ const response = await fetch(url, { signal: controller.signal });
17
+ if (!response.ok) {
18
+ throw new Error(`ClinicalTrials.gov API error: ${response.status} ${response.statusText}`);
19
+ }
20
+ return response;
21
+ }
22
+ finally {
23
+ clearTimeout(timeout);
24
+ }
25
+ }
26
+ function str(value) {
27
+ return value != null ? String(value) : "";
28
+ }
29
+ function studyToSummary(study) {
30
+ const proto = study.protocolSection;
31
+ if (!proto) {
32
+ return {
33
+ nct_id: "",
34
+ title: "",
35
+ status: "",
36
+ phase: "",
37
+ conditions: [],
38
+ interventions: [],
39
+ enrollment: null,
40
+ sponsor: "",
41
+ start_date: "",
42
+ completion_date: "",
43
+ study_type: "",
44
+ url: "",
45
+ };
46
+ }
47
+ const id = proto.identificationModule;
48
+ const status = proto.statusModule;
49
+ const design = proto.designModule;
50
+ const conditions = proto.conditionsModule;
51
+ const arms = proto.armsInterventionsModule;
52
+ const sponsor = proto.sponsorCollaboratorsModule;
53
+ const interventionList = arms?.interventions ?? [];
54
+ const interventions = interventionList.map((i) => ({
55
+ type: str(i.type),
56
+ name: str(i.name),
57
+ }));
58
+ const startDateStruct = status?.startDateStruct;
59
+ const completionDateStruct = status?.completionDateStruct;
60
+ const enrollmentInfo = design?.enrollmentInfo;
61
+ const leadSponsor = sponsor?.leadSponsor;
62
+ const phases = design?.phases ?? [];
63
+ const nctId = str(id?.nctId);
64
+ return {
65
+ nct_id: nctId,
66
+ title: str(id?.briefTitle),
67
+ status: str(status?.overallStatus),
68
+ phase: phases.join("/") || "N/A",
69
+ conditions: conditions?.conditions ?? [],
70
+ interventions,
71
+ enrollment: enrollmentInfo?.count != null ? Number(enrollmentInfo.count) : null,
72
+ sponsor: str(leadSponsor?.name),
73
+ start_date: str(startDateStruct?.date),
74
+ completion_date: str(completionDateStruct?.date),
75
+ study_type: str(design?.studyType),
76
+ url: nctId ? `https://clinicaltrials.gov/study/${nctId}` : "",
77
+ };
78
+ }
79
+ export async function searchTrials(params) {
80
+ const cacheKey = `ct:search:${JSON.stringify(params)}`;
81
+ const cached = cache.get(cacheKey);
82
+ if (cached)
83
+ return cached;
84
+ const url = new URL(`${BASE_URL}/studies`);
85
+ // Build query.cond / query.intr / query.term
86
+ if (params.condition)
87
+ url.searchParams.set("query.cond", params.condition);
88
+ if (params.intervention)
89
+ url.searchParams.set("query.intr", params.intervention);
90
+ if (params.term)
91
+ url.searchParams.set("query.term", params.term);
92
+ // Filters
93
+ if (params.status)
94
+ url.searchParams.set("filter.overallStatus", params.status);
95
+ if (params.phase)
96
+ url.searchParams.set("filter.phase", params.phase);
97
+ // Limit fields to keep payload small
98
+ url.searchParams.set("fields", [
99
+ "NCTId",
100
+ "BriefTitle",
101
+ "OverallStatus",
102
+ "Phase",
103
+ "Condition",
104
+ "InterventionName",
105
+ "InterventionType",
106
+ "EnrollmentCount",
107
+ "LeadSponsorName",
108
+ "StartDate",
109
+ "CompletionDate",
110
+ "StudyType",
111
+ ].join("|"));
112
+ url.searchParams.set("pageSize", String(params.maxResults ?? 10));
113
+ // Sort
114
+ const sortMap = {
115
+ relevance: "",
116
+ last_updated: "LastUpdatePostDate",
117
+ start_date: "StudyFirstPostDate",
118
+ enrollment: "EnrollmentCount",
119
+ };
120
+ const sortValue = sortMap[params.sort ?? "relevance"];
121
+ if (sortValue)
122
+ url.searchParams.set("sort", sortValue);
123
+ url.searchParams.set("format", "json");
124
+ const response = await rateLimitedFetch(url.toString());
125
+ const data = await response.json();
126
+ const studies = data.studies ?? [];
127
+ const results = studies.map(studyToSummary);
128
+ const totalCount = data.totalCount ?? results.length;
129
+ const result = { results, total_count: totalCount };
130
+ cache.set(cacheKey, result, TTL.SEARCH);
131
+ return result;
132
+ }
133
+ export async function getTrialDetail(nctId) {
134
+ const cacheKey = `ct:detail:${nctId}`;
135
+ const cached = cache.get(cacheKey);
136
+ if (cached)
137
+ return cached;
138
+ const url = `${BASE_URL}/studies/${encodeURIComponent(nctId)}?format=json`;
139
+ const response = await rateLimitedFetch(url);
140
+ const study = await response.json();
141
+ const summary = studyToSummary(study);
142
+ const proto = study.protocolSection;
143
+ const id = proto?.identificationModule;
144
+ const desc = proto?.descriptionModule;
145
+ const eligibility = proto?.eligibilityModule;
146
+ const designModule = proto?.designModule;
147
+ const armsModule = proto?.armsInterventionsModule;
148
+ const outcomesModule = proto?.outcomesModule;
149
+ const contactsModule = proto?.contactsLocationsModule;
150
+ const refsModule = proto?.referencesModule;
151
+ // Design info
152
+ const designInfo = designModule?.designInfo;
153
+ const maskingInfo = designInfo?.maskingInfo;
154
+ const design = {
155
+ allocation: str(designInfo?.allocation),
156
+ intervention_model: str(designInfo?.interventionModel),
157
+ primary_purpose: str(designInfo?.primaryPurpose),
158
+ masking: str(maskingInfo?.masking),
159
+ who_masked: maskingInfo?.whoMasked ?? [],
160
+ };
161
+ // Arms
162
+ const armGroups = armsModule?.armGroups ?? [];
163
+ const arms = armGroups.map((a) => ({
164
+ label: str(a.label),
165
+ type: str(a.type),
166
+ description: str(a.description),
167
+ intervention_names: a.interventionNames ?? [],
168
+ }));
169
+ // Outcomes
170
+ const parseOutcomes = (list) => {
171
+ const items = list ?? [];
172
+ return items.map((o) => ({
173
+ measure: str(o.measure),
174
+ description: str(o.description),
175
+ time_frame: str(o.timeFrame),
176
+ }));
177
+ };
178
+ const primaryOutcomes = parseOutcomes(outcomesModule?.primaryOutcomes);
179
+ const secondaryOutcomes = parseOutcomes(outcomesModule?.secondaryOutcomes);
180
+ // Locations count
181
+ const locations = contactsModule?.locations ?? [];
182
+ // Lead investigator
183
+ const overallOfficials = contactsModule?.overallOfficials ?? [];
184
+ const leadInvestigator = overallOfficials.length > 0 ? str(overallOfficials[0].name) : "";
185
+ // Associated PMIDs
186
+ const references = refsModule?.references ?? [];
187
+ const pmids = references
188
+ .map((r) => str(r.pmid))
189
+ .filter((p) => p !== "");
190
+ const detail = {
191
+ ...summary,
192
+ official_title: str(id?.officialTitle),
193
+ summary: str(desc?.briefSummary),
194
+ eligibility: {
195
+ criteria: str(eligibility?.eligibilityCriteria),
196
+ gender: str(eligibility?.sex),
197
+ minimum_age: str(eligibility?.minimumAge),
198
+ maximum_age: str(eligibility?.maximumAge),
199
+ healthy_volunteers: str(eligibility?.healthyVolunteers),
200
+ },
201
+ design,
202
+ arms,
203
+ primary_outcomes: primaryOutcomes,
204
+ secondary_outcomes: secondaryOutcomes,
205
+ locations_count: locations.length,
206
+ lead_investigator: leadInvestigator,
207
+ associated_pmids: pmids,
208
+ url: `https://clinicaltrials.gov/study/${nctId}`,
209
+ };
210
+ cache.set(cacheKey, detail, TTL.TRIAL);
211
+ return detail;
212
+ }
213
+ //# sourceMappingURL=clinicaltrials.js.map
package/dist/lib/clinicaltrials.js.map ADDED
@@ -0,0 +1 @@
1
+ {"version":3,"file":"clinicaltrials.js","sourceRoot":"","sources":["../../src/lib/clinicaltrials.ts"],"names":[],"mappings":"AAAA,OAAO,EAAE,KAAK,EAAE,GAAG,EAAE,MAAM,YAAY,CAAC;AAUxC,MAAM,QAAQ,GAAG,mCAAmC,CAAC;AACrD,MAAM,gBAAgB,GAAG,IAAI,CAAC,CAAC,cAAc;AAC7C,MAAM,UAAU,GAAG,KAAK,CAAC;AAEzB,IAAI,eAAe,GAAG,CAAC,CAAC;AAExB,KAAK,UAAU,gBAAgB,CAAC,GAAW;IACzC,MAAM,GAAG,GAAG,IAAI,CAAC,GAAG,EAAE,CAAC;IACvB,MAAM,OAAO,GAAG,GAAG,GAAG,eAAe,CAAC;IAEtC,IAAI,OAAO,GAAG,gBAAgB,EAAE,CAAC;QAC/B,MAAM,IAAI,OAAO,CAAC,CAAC,OAAO,EAAE,EAAE,CAAC,UAAU,CAAC,OAAO,EAAE,gBAAgB,GAAG,OAAO,CAAC,CAAC,CAAC;IAClF,CAAC;IAED,eAAe,GAAG,IAAI,CAAC,GAAG,EAAE,CAAC;IAE7B,MAAM,UAAU,GAAG,IAAI,eAAe,EAAE,CAAC;IACzC,MAAM,OAAO,GAAG,UAAU,CAAC,GAAG,EAAE,CAAC,UAAU,CAAC,KAAK,EAAE,EAAE,UAAU,CAAC,CAAC;IAEjE,IAAI,CAAC;QACH,MAAM,QAAQ,GAAG,MAAM,KAAK,CAAC,GAAG,EAAE,EAAE,MAAM,EAAE,UAAU,CAAC,MAAM,EAAE,CAAC,CAAC;QACjE,IAAI,CAAC,QAAQ,CAAC,EAAE,EAAE,CAAC;YACjB,MAAM,IAAI,KAAK,CAAC,iCAAiC,QAAQ,CAAC,MAAM,IAAI,QAAQ,CAAC,UAAU,EAAE,CAAC,CAAC;QAC7F,CAAC;QACD,OAAO,QAAQ,CAAC;IAClB,CAAC;YAAS,CAAC;QACT,YAAY,CAAC,OAAO,CAAC,CAAC;IACxB,CAAC;AACH,CAAC;AAED,SAAS,GAAG,CAAC,KAAc;IACzB,OAAO,KAAK,IAAI,IAAI,CAAC,CAAC,CAAC,MAAM,CAAC,KAAK,CAAC,CAAC,CAAC,CAAC,EAAE,CAAC;AAC5C,CAAC;AAED,SAAS,cAAc,CAAC,KAA8B;IACpD,MAAM,KAAK,GAAG,KAAK,CAAC,eAAsD,CAAC;IAC3E,IAAI,CAAC,KAAK,EAAE,CAAC;QACX,OAAO;YACL,MAAM,EAAE,EAAE;YACV,KAAK,EAAE,EAAE;YACT,MAAM,EAAE,EAAE;YACV,KAAK,EAAE,EAAE;YACT,UAAU,EAAE,EAAE;YACd,aAAa,EAAE,EAAE;YACjB,UAAU,EAAE,IAAI;YAChB,OAAO,EAAE,EAAE;YACX,UAAU,EAAE,EAAE;YACd,eAAe,EAAE,EAAE;YACnB,UAAU,EAAE,EAAE;YACd,GAAG,EAAE,EAAE;SACR,CAAC;IACJ,CAAC;IAED,MAAM,EAAE,GAAG,KAAK,CAAC,oBAA2D,CAAC;IAC7E,MAAM,MAAM,GAAG,KAAK,CAAC,YAAmD,CAAC;IACzE,MAAM,MAAM,GAAG,KAAK,CAAC,YAAmD,CAAC;IACzE,MAAM,UAAU,GAAG,KAAK,CAAC,gBAAuD,CAAC;IACjF,MAAM,IAAI,GAAG,KAAK,CAAC,uBAA8D,CAAC;IAClF,MAAM,OAAO,GAAG,KAAK,CAAC,0BAAiE,CAAC;IAExF,MAAM,gBAAgB,GAAI,IAAI,EAAE,aAA4D,IAAI,EAAE,CAAC;IACnG,MAAM,aAAa,GAAwB,gBAAgB,CAAC,GAAG,CAAC,CAAC,CAAC,EAAE,EAAE,CAAC,CAAC;QACtE,IAAI,EAAE,GAAG,CAAC,CAAC,CAAC,IAAI,CAAC;QACjB,IAAI,EAAE,GAAG,CAAC,CAAC,CAAC,IAAI,CAAC;KAClB,CAAC,CAAC,CAAC;IAEJ,MAAM,eAAe,GAAG,MAAM,EAAE,eAAsD,CAAC;IACvF,MAAM,oBAAoB,GAAG,MAAM,EAAE,oBAA2D,CAAC;IACjG,MAAM,cAAc,GAAG,MAAM,EAAE,cAAqD,CAAC;IACrF,MAAM,WAAW,GAAG,OAAO,EAAE,WAAkD,CAAC;IAEhF,MAAM,MAAM,GAAI,MAAM,EAAE,MAA+B,IAAI,EAAE,CAAC;IAE9D,MAAM,KAAK,GAAG,GAAG,CAAC,EAAE,EAAE,KAAK,CAAC,CAAC;IAE7B,OAAO;QACL,MAAM,EAAE,KAAK;QACb,KAAK,EAAE,GAAG,CAAC,EAAE,EAAE,UAAU,CAAC;QAC1B,MAAM,EAAE,GAAG,CAAC,MAAM,EAAE,aAAa,CAAC;QAClC,KAAK,EAAE,MAAM,CAAC,IAAI,CAAC,GAAG,CAAC,IAAI,KAAK;QAChC,UAAU,EAAG,UAAU,EAAE,UAAmC,IAAI,EAAE;QAClE,aAAa;QACb,UAAU,EAAE,cAAc,EAAE,KAAK,IAAI,IAAI,CAAC,CAAC,CAAC,MAAM,CAAC,cAAc,CAAC,KAAK,CAAC,CAAC,CAAC,CAAC,IAAI;QAC/E,OAAO,EAAE,GAAG,CAAC,WAAW,EAAE,IAAI,CAAC;QAC/B,UAAU,EAAE,GAAG,CAAC,eAAe,EAAE,IAAI,CAAC;QACtC,eAAe,EAAE,GAAG,CAAC,oBAAoB,EAAE,IAAI,CAAC;QAChD,UAAU,EAAE,GAAG,CAAC,MAAM,EAAE,SAAS,CAAC;QAClC,GAAG,EAAE,KAAK,CAAC,CAAC,CAAC,oCAAoC,KAAK,EAAE,CAAC,CAAC,CAAC,EAAE;KAC9D,CAAC;AACJ,CAAC;AAED,MAAM,CAAC,KAAK,UAAU,YAAY,CAAC,MAQlC;IACC,MAAM,QAAQ,GAAG,aAAa,IAAI,CAAC,SAAS,CAAC,MAAM,CAAC,EAAE,CAAC;IACvD,MAAM,MAAM,GAAG,KAAK,CAAC,GAAG,CAA2D,QAAQ,CAAC,CAAC;IAC7F,IAAI,MAAM;QAAE,OAAO,MAAM,CAAC;IAE1B,MAAM,GAAG,GAAG,IAAI,GAAG,CAAC,GAAG,QAAQ,UAAU,CAAC,CAAC;IAE3C,6CAA6C;IAC7C,IAAI,MAAM,CAAC,SAAS;QAAE,GAAG,CAAC,YAAY,CAAC,GAAG,CAAC,YAAY,EAAE,MAAM,CAAC,SAAS,CAAC,CAAC;IAC3E,IAAI,MAAM,CAAC,YAAY;QAAE,GAAG,CAAC,YAAY,CAAC,GAAG,CAAC,YAAY,EAAE,MAAM,CAAC,YAAY,CAAC,CAAC;IACjF,IAAI,MAAM,CAAC,IAAI;QAAE,GAAG,CAAC,YAAY,CAAC,GAAG,CAAC,YAAY,EAAE,MAAM,CAAC,IAAI,CAAC,CAAC;IAEjE,UAAU;IACV,IAAI,MAAM,CAAC,MAAM;QAAE,GAAG,CAAC,YAAY,CAAC,GAAG,CAAC,sBAAsB,EAAE,MAAM,CAAC,MAAM,CAAC,CAAC;IAC/E,IAAI,MAAM,CAAC,KAAK;QAAE,GAAG,CAAC,YAAY,CAAC,GAAG,CAAC,cAAc,EAAE,MAAM,CAAC,KAAK,CAAC,CAAC;IAErE,qCAAqC;IACrC,GAAG,CAAC,YAAY,CAAC,GAAG,CAClB,QAAQ,EACR;QACE,OAAO;QACP,YAAY;QACZ,eAAe;QACf,OAAO;QACP,WAAW;QACX,kBAAkB;QAClB,kBAAkB;QAClB,iBAAiB;QACjB,iBAAiB;QACjB,WAAW;QACX,gBAAgB;QAChB,WAAW;KACZ,CAAC,IAAI,CAAC,GAAG,CAAC,CACZ,CAAC;IAEF,GAAG,CAAC,YAAY,CAAC,GAAG,CAAC,UAAU,EAAE,MAAM,CAAC,MAAM,CAAC,UAAU,IAAI,EAAE,CAAC,CAAC,CAAC;IAElE,OAAO;IACP,MAAM,OAAO,GAA2B;QACtC,SAAS,EAAE,EAAE;QACb,YAAY,EAAE,oBAAoB;QAClC,UAAU,EAAE,oBAAoB;QAChC,UAAU,EAAE,iBAAiB;KAC9B,CAAC;IACF,MAAM,SAAS,GAAG,OAAO,CAAC,MAAM,CAAC,IAAI,IAAI,WAAW,CAAC,CAAC;IACtD,IAAI,SAAS;QAAE,GAAG,CAAC,YAAY,CAAC,GAAG,CAAC,MAAM,EAAE,SAAS,CAAC,CAAC;IAEvD,GAAG,CAAC,YAAY,CAAC,GAAG,CAAC,QAAQ,EAAE,MAAM,CAAC,CAAC;IAEvC,MAAM,QAAQ,GAAG,MAAM,gBAAgB,CAAC,GAAG,CAAC,QAAQ,EAAE,CAAC,CAAC;IACxD,MAAM,IAAI,GAAG,MAAM,QAAQ,CAAC,IAAI,EAAE,CAAC;IAEnC,MAAM,OAAO,GAAI,IAAI,CAAC,OAAsD,IAAI,EAAE,CAAC;IACnF,MAAM,OAAO,GAAG,OAAO,CAAC,GAAG,CAAC,cAAc,CAAC,CAAC;IAC5C,MAAM,UAAU,GAAI,IAAI,CAAC,UAAiC,IAAI,OAAO,CAAC,MAAM,CAAC;IAE7E,MAAM,MAAM,GAAG,EAAE,OAAO,EAAE,WAAW,EAAE,UAAU,EAAE,CAAC;IACpD,KAAK,CAAC,GAAG,CAAC,QAAQ,EAAE,MAAM,EAAE,GAAG,CAAC,MAAM,CAAC,CAAC;IACxC,OAAO,MAAM,CAAC;AAChB,CAAC;AAED,MAAM,CAAC,KAAK,UAAU,cAAc,CAAC,KAAa;IAChD,MAAM,QAAQ,GAAG,aAAa,KAAK,EAAE,CAAC;IACtC,MAAM,MAAM,GAAG,KAAK,CAAC,GAAG,CAAsB,QAAQ,CAAC,CAAC;IACxD,IAAI,MAAM;QAAE,OAAO,MAAM,CAAC;IAE1B,MAAM,GAAG,GAAG,GAAG,QAAQ,YAAY,kBAAkB,CAAC,KAAK,CAAC,cAAc,CAAC;IAC3E,MAAM,QAAQ,GAAG,MAAM,gBAAgB,CAAC,GAAG,CAAC,CAAC;IAC7C,MAAM,KAAK,GAAG,MAAM,QAAQ,CAAC,IAAI,EAA6B,CAAC;IAE/D,MAAM,OAAO,GAAG,cAAc,CAAC,KAAK,CAAC,CAAC;IACtC,MAAM,KAAK,GAAG,KAAK,CAAC,eAAsD,CAAC;IAE3E,MAAM,EAAE,GAAG,KAAK,EAAE,oBAA2D,CAAC;IAC9E,MAAM,IAAI,GAAG,KAAK,EAAE,iBAAwD,CAAC;IAC7E,MAAM,WAAW,GAAG,KAAK,EAAE,iBAAwD,CAAC;IACpF,MAAM,YAAY,GAAG,KAAK,EAAE,YAAmD,CAAC;IAChF,MAAM,UAAU,GAAG,KAAK,EAAE,uBAA8D,CAAC;IACzF,MAAM,cAAc,GAAG,KAAK,EAAE,cAAqD,CAAC;IACpF,MAAM,cAAc,GAAG,KAAK,EAAE,uBAA8D,CAAC;IAC7F,MAAM,UAAU,GAAG,KAAK,EAAE,gBAAuD,CAAC;IAElF,cAAc;IACd,MAAM,UAAU,GAAG,YAAY,EAAE,UAAiD,CAAC;IACnF,MAAM,WAAW,GAAG,UAAU,EAAE,WAAkD,CAAC;IACnF,MAAM,MAAM,GAAgB;QAC1B,UAAU,EAAE,GAAG,CAAC,UAAU,EAAE,UAAU,CAAC;QACvC,kBAAkB,EAAE,GAAG,CAAC,UAAU,EAAE,iBAAiB,CAAC;QACtD,eAAe,EAAE,GAAG,CAAC,UAAU,EAAE,cAAc,CAAC;QAChD,OAAO,EAAE,GAAG,CAAC,WAAW,EAAE,OAAO,CAAC;QAClC,UAAU,EAAG,WAAW,EAAE,SAAkC,IAAI,EAAE;KACnE,CAAC;IAEF,OAAO;IACP,MAAM,SAAS,GAAI,UAAU,EAAE,SAAwD,IAAI,EAAE,CAAC;IAC9F,MAAM,IAAI,GAAoB,SAAS,CAAC,GAAG,CAAC,CAAC,CAAC,EAAE,EAAE,CAAC,CAAC;QAClD,KAAK,EAAE,GAAG,CAAC,CAAC,CAAC,KAAK,CAAC;QACnB,IAAI,EAAE,GAAG,CAAC,CAAC,CAAC,IAAI,CAAC;QACjB,WAAW,EAAE,GAAG,CAAC,CAAC,CAAC,WAAW,CAAC;QAC/B,kBAAkB,EAAG,CAAC,CAAC,iBAA0C,IAAI,EAAE;KACxE,CAAC,CAAC,CAAC;IAEJ,WAAW;IACX,MAAM,aAAa,GAAG,CAAC,IAAa,EAAkB,EAAE;QACtD,MAAM,KAAK,GAAI,IAAmD,IAAI,EAAE,CAAC;QACzE,OAAO,KAAK,CAAC,GAAG,CAAC,CAAC,CAAC,EAAE,EAAE,CAAC,CAAC;YACvB,OAAO,EAAE,GAAG,CAAC,CAAC,CAAC,OAAO,CAAC;YACvB,WAAW,EAAE,GAAG,CAAC,CAAC,CAAC,WAAW,CAAC;YAC/B,UAAU,EAAE,GAAG,CAAC,CAAC,CAAC,SAAS,CAAC;SAC7B,CAAC,CAAC,CAAC;IACN,CAAC,CAAC;IAEF,MAAM,eAAe,GAAG,aAAa,CAAC,cAAc,EAAE,eAAe,CAAC,CAAC;IACvE,MAAM,iBAAiB,GAAG,aAAa,CAAC,cAAc,EAAE,iBAAiB,CAAC,CAAC;IAE3E,kBAAkB;IAClB,MAAM,SAAS,GAAI,cAAc,EAAE,SAAmC,IAAI,EAAE,CAAC;IAE7E,oBAAoB;IACpB,MAAM,gBAAgB,GAAI,cAAc,EAAE,gBAA+D,IAAI,EAAE,CAAC;IAChH,MAAM,gBAAgB,GAAG,gBAAgB,CAAC,MAAM,GAAG,CAAC,CAAC,CAAC,CAAC,GAAG,CAAC,gBAAgB,CAAC,CAAC,CAAC,CAAC,IAAI,CAAC,CAAC,CAAC,CAAC,EAAE,CAAC;IAE1F,mBAAmB;IACnB,MAAM,UAAU,GAAI,UAAU,EAAE,UAAyD,IAAI,EAAE,CAAC;IAChG,MAAM,KAAK,GAAG,UAAU;SACrB,GAAG,CAAC,CAAC,CAAC,EAAE,EAAE,CAAC,GAAG,CAAC,CAAC,CAAC,IAAI,CAAC,CAAC;SACvB,MAAM,CAAC,CAAC,CAAC,EAAE,EAAE,CAAC,CAAC,KAAK,EAAE,CAAC,CAAC;IAE3B,MAAM,MAAM,GAAwB;QAClC,GAAG,OAAO;QACV,cAAc,EAAE,GAAG,CAAC,EAAE,EAAE,aAAa,CAAC;QACtC,OAAO,EAAE,GAAG,CAAC,IAAI,EAAE,YAAY,CAAC;QAChC,WAAW,EAAE;YACX,QAAQ,EAAE,GAAG,CAAC,WAAW,EAAE,mBAAmB,CAAC;YAC/C,MAAM,EAAE,GAAG,CAAC,WAAW,EAAE,GAAG,CAAC;YAC7B,WAAW,EAAE,GAAG,CAAC,WAAW,EAAE,UAAU,CAAC;YACzC,WAAW,EAAE,GAAG,CAAC,WAAW,EAAE,UAAU,CAAC;YACzC,kBAAkB,EAAE,GAAG,CAAC,WAAW,EAAE,iBAAiB,CAAC;SACxD;QACD,MAAM;QACN,IAAI;QACJ,gBAAgB,EAAE,eAAe;QACjC,kBAAkB,EAAE,iBAAiB;QACrC,eAAe,EAAE,SAAS,CAAC,MAAM;QACjC,iBAAiB,EAAE,gBAAgB;QACnC,gBAAgB,EAAE,KAAK;QACvB,GAAG,EAAE,oCAAoC,KAAK,EAAE;KACjD,CAAC;IAEF,KAAK,CAAC,GAAG,CAAC,QAAQ,EAAE,MAAM,EAAE,GAAG,CAAC,KAAK,CAAC,CAAC;IACvC,OAAO,MAAM,CAAC;AAChB,CAAC"}
package/dist/tools/trials-detail.d.ts ADDED
@@ -0,0 +1,3 @@
1
+ import { McpServer } from "@modelcontextprotocol/sdk/server/mcp.js";
2
+ export declare function registerTrialDetailTool(server: McpServer): void;
3
+ //# sourceMappingURL=trials-detail.d.ts.map
package/dist/tools/trials-detail.d.ts.map ADDED
@@ -0,0 +1 @@
1
+ {"version":3,"file":"trials-detail.d.ts","sourceRoot":"","sources":["../../src/tools/trials-detail.ts"],"names":[],"mappings":"AACA,OAAO,EAAE,SAAS,EAAE,MAAM,yCAAyC,CAAC;AAUpE,wBAAgB,uBAAuB,CAAC,MAAM,EAAE,SAAS,GAAG,IAAI,CAuC/D"}
package/dist/tools/trials-detail.js ADDED
@@ -0,0 +1,38 @@
1
+ import { z } from "zod";
2
+ import { getTrialDetail } from "../lib/clinicaltrials.js";
3
+ const schema = {
4
+ nctId: z
5
+ .string()
6
+ .regex(/^NCT\d{8}$/, "Must be a valid NCT ID (e.g., NCT12345678)")
7
+ .describe("ClinicalTrials.gov NCT identifier (e.g., NCT03086486)"),
8
+ };
9
+ export function registerTrialDetailTool(server) {
10
+ server.tool("get_trial", "Get detailed information about a specific clinical trial from ClinicalTrials.gov. Returns eligibility criteria, study design, arms, outcomes, locations, and associated PubMed IDs.", schema, async (params) => {
11
+ try {
12
+ const detail = await getTrialDetail(params.nctId);
13
+ return {
14
+ content: [{
15
+ type: "text",
16
+ text: JSON.stringify(detail, null, 2),
17
+ }],
18
+ };
19
+ }
20
+ catch (error) {
21
+ const message = error instanceof Error ? error.message : String(error);
22
+ if (message.includes("404")) {
23
+ return {
24
+ content: [{
25
+ type: "text",
26
+ text: JSON.stringify({ error: `Clinical trial ${params.nctId} not found. Verify the NCT ID is correct.` }, null, 2),
27
+ }],
28
+ isError: true,
29
+ };
30
+ }
31
+ return {
32
+ content: [{ type: "text", text: `Error fetching trial details: ${message}` }],
33
+ isError: true,
34
+ };
35
+ }
36
+ });
37
+ }
38
+ //# sourceMappingURL=trials-detail.js.map
package/dist/tools/trials-detail.js.map ADDED
@@ -0,0 +1 @@
1
+ {"version":3,"file":"trials-detail.js","sourceRoot":"","sources":["../../src/tools/trials-detail.ts"],"names":[],"mappings":"AAAA,OAAO,EAAE,CAAC,EAAE,MAAM,KAAK,CAAC;AAExB,OAAO,EAAE,cAAc,EAAE,MAAM,0BAA0B,CAAC;AAE1D,MAAM,MAAM,GAAG;IACb,KAAK,EAAE,CAAC;SACL,MAAM,EAAE;SACR,KAAK,CAAC,YAAY,EAAE,4CAA4C,CAAC;SACjE,QAAQ,CAAC,uDAAuD,CAAC;CACrE,CAAC;AAEF,MAAM,UAAU,uBAAuB,CAAC,MAAiB;IACvD,MAAM,CAAC,IAAI,CACT,WAAW,EACX,qLAAqL,EACrL,MAAM,EACN,KAAK,EAAE,MAAM,EAAE,EAAE;QACf,IAAI,CAAC;YACH,MAAM,MAAM,GAAG,MAAM,cAAc,CAAC,MAAM,CAAC,KAAK,CAAC,CAAC;YAElD,OAAO;gBACL,OAAO,EAAE,CAAC;wBACR,IAAI,EAAE,MAAM;wBACZ,IAAI,EAAE,IAAI,CAAC,SAAS,CAAC,MAAM,EAAE,IAAI,EAAE,CAAC,CAAC;qBACtC,CAAC;aACH,CAAC;QACJ,CAAC;QAAC,OAAO,KAAK,EAAE,CAAC;YACf,MAAM,OAAO,GAAG,KAAK,YAAY,KAAK,CAAC,CAAC,CAAC,KAAK,CAAC,OAAO,CAAC,CAAC,CAAC,MAAM,CAAC,KAAK,CAAC,CAAC;YAEvE,IAAI,OAAO,CAAC,QAAQ,CAAC,KAAK,CAAC,EAAE,CAAC;gBAC5B,OAAO;oBACL,OAAO,EAAE,CAAC;4BACR,IAAI,EAAE,MAAM;4BACZ,IAAI,EAAE,IAAI,CAAC,SAAS,CAClB,EAAE,KAAK,EAAE,kBAAkB,MAAM,CAAC,KAAK,2CAA2C,EAAE,EACpF,IAAI,EACJ,CAAC,CACF;yBACF,CAAC;oBACF,OAAO,EAAE,IAAI;iBACd,CAAC;YACJ,CAAC;YAED,OAAO;gBACL,OAAO,EAAE,CAAC,EAAE,IAAI,EAAE,MAAM,EAAE,IAAI,EAAE,iCAAiC,OAAO,EAAE,EAAE,CAAC;gBAC7E,OAAO,EAAE,IAAI;aACd,CAAC;QACJ,CAAC;IACH,CAAC,CACF,CAAC;AACJ,CAAC"}
package/dist/tools/trials-search.d.ts ADDED
@@ -0,0 +1,3 @@
1
+ import { McpServer } from "@modelcontextprotocol/sdk/server/mcp.js";
2
+ export declare function registerTrialsSearchTool(server: McpServer): void;
3
+ //# sourceMappingURL=trials-search.d.ts.map
package/dist/tools/trials-search.d.ts.map ADDED
@@ -0,0 +1 @@
1
+ {"version":3,"file":"trials-search.d.ts","sourceRoot":"","sources":["../../src/tools/trials-search.ts"],"names":[],"mappings":"AACA,OAAO,EAAE,SAAS,EAAE,MAAM,yCAAyC,CAAC;AA8BpE,wBAAgB,wBAAwB,CAAC,MAAM,EAAE,SAAS,GAAG,IAAI,CA8ChE"}
package/dist/tools/trials-search.js ADDED
@@ -0,0 +1,66 @@
1
+ import { z } from "zod";
2
+ import { searchTrials } from "../lib/clinicaltrials.js";
3
+ const schema = {
4
+ condition: z.string().optional().describe("Disease or condition (e.g., 'breast cancer', 'diabetes')"),
5
+ intervention: z.string().optional().describe("Drug or therapy (e.g., 'pembrolizumab', 'radiation')"),
6
+ term: z.string().optional().describe("General search term (searches all fields)"),
7
+ status: z
8
+ .enum([
9
+ "RECRUITING",
10
+ "COMPLETED",
11
+ "ACTIVE_NOT_RECRUITING",
12
+ "NOT_YET_RECRUITING",
13
+ "TERMINATED",
14
+ "WITHDRAWN",
15
+ "SUSPENDED",
16
+ ])
17
+ .optional()
18
+ .describe("Trial recruitment status filter"),
19
+ phase: z
20
+ .enum(["EARLY_PHASE1", "PHASE1", "PHASE2", "PHASE3", "PHASE4", "NA"])
21
+ .optional()
22
+ .describe("Trial phase filter"),
23
+ maxResults: z.number().min(1).max(100).default(10).describe("Maximum number of results (1-100)"),
24
+ sort: z
25
+ .enum(["relevance", "last_updated", "start_date", "enrollment"])
26
+ .default("relevance")
27
+ .describe("Sort order for results"),
28
+ };
29
+ export function registerTrialsSearchTool(server) {
30
+ server.tool("search_trials", "Search ClinicalTrials.gov for clinical trials. Filter by condition, intervention, status, and phase. Returns trial summaries with NCT IDs, status, sponsors, and enrollment info.", schema, async (params) => {
31
+ try {
32
+ if (!params.condition && !params.intervention && !params.term) {
33
+ return {
34
+ content: [{
35
+ type: "text",
36
+ text: JSON.stringify({ error: "At least one of condition, intervention, or term is required" }, null, 2),
37
+ }],
38
+ isError: true,
39
+ };
40
+ }
41
+ const result = await searchTrials({
42
+ condition: params.condition,
43
+ intervention: params.intervention,
44
+ term: params.term,
45
+ status: params.status,
46
+ phase: params.phase,
47
+ maxResults: params.maxResults,
48
+ sort: params.sort,
49
+ });
50
+ return {
51
+ content: [{
52
+ type: "text",
53
+ text: JSON.stringify(result, null, 2),
54
+ }],
55
+ };
56
+ }
57
+ catch (error) {
58
+ const message = error instanceof Error ? error.message : String(error);
59
+ return {
60
+ content: [{ type: "text", text: `Error searching ClinicalTrials.gov: ${message}` }],
61
+ isError: true,
62
+ };
63
+ }
64
+ });
65
+ }
66
+ //# sourceMappingURL=trials-search.js.map
package/dist/tools/trials-search.js.map ADDED
@@ -0,0 +1 @@
1
+ {"version":3,"file":"trials-search.js","sourceRoot":"","sources":["../../src/tools/trials-search.ts"],"names":[],"mappings":"AAAA,OAAO,EAAE,CAAC,EAAE,MAAM,KAAK,CAAC;AAExB,OAAO,EAAE,YAAY,EAAE,MAAM,0BAA0B,CAAC;AAExD,MAAM,MAAM,GAAG;IACb,SAAS,EAAE,CAAC,CAAC,MAAM,EAAE,CAAC,QAAQ,EAAE,CAAC,QAAQ,CAAC,0DAA0D,CAAC;IACrG,YAAY,EAAE,CAAC,CAAC,MAAM,EAAE,CAAC,QAAQ,EAAE,CAAC,QAAQ,CAAC,sDAAsD,CAAC;IACpG,IAAI,EAAE,CAAC,CAAC,MAAM,EAAE,CAAC,QAAQ,EAAE,CAAC,QAAQ,CAAC,2CAA2C,CAAC;IACjF,MAAM,EAAE,CAAC;SACN,IAAI,CAAC;QACJ,YAAY;QACZ,WAAW;QACX,uBAAuB;QACvB,oBAAoB;QACpB,YAAY;QACZ,WAAW;QACX,WAAW;KACZ,CAAC;SACD,QAAQ,EAAE;SACV,QAAQ,CAAC,iCAAiC,CAAC;IAC9C,KAAK,EAAE,CAAC;SACL,IAAI,CAAC,CAAC,cAAc,EAAE,QAAQ,EAAE,QAAQ,EAAE,QAAQ,EAAE,QAAQ,EAAE,IAAI,CAAC,CAAC;SACpE,QAAQ,EAAE;SACV,QAAQ,CAAC,oBAAoB,CAAC;IACjC,UAAU,EAAE,CAAC,CAAC,MAAM,EAAE,CAAC,GAAG,CAAC,CAAC,CAAC,CAAC,GAAG,CAAC,GAAG,CAAC,CAAC,OAAO,CAAC,EAAE,CAAC,CAAC,QAAQ,CAAC,mCAAmC,CAAC;IAChG,IAAI,EAAE,CAAC;SACJ,IAAI,CAAC,CAAC,WAAW,EAAE,cAAc,EAAE,YAAY,EAAE,YAAY,CAAC,CAAC;SAC/D,OAAO,CAAC,WAAW,CAAC;SACpB,QAAQ,CAAC,wBAAwB,CAAC;CACtC,CAAC;AAEF,MAAM,UAAU,wBAAwB,CAAC,MAAiB;IACxD,MAAM,CAAC,IAAI,CACT,eAAe,EACf,mLAAmL,EACnL,MAAM,EACN,KAAK,EAAE,MAAM,EAAE,EAAE;QACf,IAAI,CAAC;YACH,IAAI,CAAC,MAAM,CAAC,SAAS,IAAI,CAAC,MAAM,CAAC,YAAY,IAAI,CAAC,MAAM,CAAC,IAAI,EAAE,CAAC;gBAC9D,OAAO;oBACL,OAAO,EAAE,CAAC;4BACR,IAAI,EAAE,MAAM;4BACZ,IAAI,EAAE,IAAI,CAAC,SAAS,CAClB,EAAE,KAAK,EAAE,8DAA8D,EAAE,EACzE,IAAI,EACJ,CAAC,CACF;yBACF,CAAC;oBACF,OAAO,EAAE,IAAI;iBACd,CAAC;YACJ,CAAC;YAED,MAAM,MAAM,GAAG,MAAM,YAAY,CAAC;gBAChC,SAAS,EAAE,MAAM,CAAC,SAAS;gBAC3B,YAAY,EAAE,MAAM,CAAC,YAAY;gBACjC,IAAI,EAAE,MAAM,CAAC,IAAI;gBACjB,MAAM,EAAE,MAAM,CAAC,MAAM;gBACrB,KAAK,EAAE,MAAM,CAAC,KAAK;gBACnB,UAAU,EAAE,MAAM,CAAC,UAAU;gBAC7B,IAAI,EAAE,MAAM,CAAC,IAAI;aAClB,CAAC,CAAC;YAEH,OAAO;gBACL,OAAO,EAAE,CAAC;wBACR,IAAI,EAAE,MAAM;wBACZ,IAAI,EAAE,IAAI,CAAC,SAAS,CAAC,MAAM,EAAE,IAAI,EAAE,CAAC,CAAC;qBACtC,CAAC;aACH,CAAC;QACJ,CAAC;QAAC,OAAO,KAAK,EAAE,CAAC;YACf,MAAM,OAAO,GAAG,KAAK,YAAY,KAAK,CAAC,CAAC,CAAC,KAAK,CAAC,OAAO,CAAC,CAAC,CAAC,MAAM,CAAC,KAAK,CAAC,CAAC;YACvE,OAAO;gBACL,OAAO,EAAE,CAAC,EAAE,IAAI,EAAE,MAAM,EAAE,IAAI,EAAE,uCAAuC,OAAO,EAAE,EAAE,CAAC;gBACnF,OAAO,EAAE,IAAI;aACd,CAAC;QACJ,CAAC;IACH,CAAC,CACF,CAAC;AACJ,CAAC"}
package/dist/types.d.ts CHANGED
@@ -90,4 +90,59 @@ export interface IndicationSearchResult {
90
90
  condition: string;
91
91
  drugs: DrugApprovalEntry[];
92
92
  }
93
+ export interface TrialIntervention {
94
+ type: string;
95
+ name: string;
96
+ }
97
+ export interface ClinicalTrialSummary {
98
+ nct_id: string;
99
+ title: string;
100
+ status: string;
101
+ phase: string;
102
+ conditions: string[];
103
+ interventions: TrialIntervention[];
104
+ enrollment: number | null;
105
+ sponsor: string;
106
+ start_date: string;
107
+ completion_date: string;
108
+ study_type: string;
109
+ url: string;
110
+ }
111
+ export interface TrialOutcome {
112
+ measure: string;
113
+ description: string;
114
+ time_frame: string;
115
+ }
116
+ export interface TrialArmGroup {
117
+ label: string;
118
+ type: string;
119
+ description: string;
120
+ intervention_names: string[];
121
+ }
122
+ export interface TrialDesign {
123
+ allocation: string;
124
+ intervention_model: string;
125
+ primary_purpose: string;
126
+ masking: string;
127
+ who_masked: string[];
128
+ }
129
+ export interface ClinicalTrialDetail extends ClinicalTrialSummary {
130
+ official_title: string;
131
+ summary: string;
132
+ eligibility: {
133
+ criteria: string;
134
+ gender: string;
135
+ minimum_age: string;
136
+ maximum_age: string;
137
+ healthy_volunteers: string;
138
+ };
139
+ design: TrialDesign;
140
+ arms: TrialArmGroup[];
141
+ primary_outcomes: TrialOutcome[];
142
+ secondary_outcomes: TrialOutcome[];
143
+ locations_count: number;
144
+ lead_investigator: string;
145
+ associated_pmids: string[];
146
+ url: string;
147
+ }
93
148
  //# sourceMappingURL=types.d.ts.map
package/dist/types.d.ts.map CHANGED
@@ -1 +1 @@
1
- {"version":3,"file":"types.d.ts","sourceRoot":"","sources":["../src/types.ts"],"names":[],"mappings":"AAAA,MAAM,WAAW,aAAa;IAC5B,IAAI,EAAE,MAAM,CAAC;IACb,KAAK,EAAE,MAAM,CAAC;IACd,OAAO,EAAE,MAAM,EAAE,CAAC;IAClB,OAAO,EAAE,MAAM,CAAC;IAChB,IAAI,EAAE,MAAM,CAAC;IACb,GAAG,EAAE,MAAM,CAAC;IACZ,gBAAgB,EAAE,MAAM,CAAC;CAC1B;AAED,MAAM,WAAW,eAAe;IAC9B,KAAK,EAAE,MAAM,CAAC;IACd,IAAI,EAAE,MAAM,CAAC;CACd;AAED,MAAM,WAAW,YAAY;IAC3B,IAAI,EAAE,MAAM,CAAC;IACb,KAAK,EAAE,MAAM,CAAC;IACd,OAAO,EAAE,MAAM,EAAE,CAAC;IAClB,OAAO,EAAE,MAAM,CAAC;IAChB,IAAI,EAAE,MAAM,CAAC;IACb,GAAG,EAAE,MAAM,CAAC;IACZ,MAAM,EAAE,MAAM,CAAC;IACf,KAAK,EAAE,MAAM,CAAC;IACd,KAAK,EAAE,MAAM,CAAC;IACd,iBAAiB,EAAE,eAAe,EAAE,CAAC;IACrC,QAAQ,EAAE,MAAM,EAAE,CAAC;IACnB,UAAU,EAAE,MAAM,EAAE,CAAC;IACrB,MAAM,EAAE,MAAM,CAAC;CAChB;AAED,MAAM,WAAW,eAAe;IAC9B,KAAK,EAAE,MAAM,CAAC;IACd,OAAO,EAAE,MAAM,CAAC;CACjB;AAED,MAAM,WAAW,cAAc;IAC7B,IAAI,EAAE,MAAM,CAAC;IACb,KAAK,EAAE,MAAM,CAAC;IACd,KAAK,EAAE,MAAM,CAAC;IACd,QAAQ,EAAE,eAAe,EAAE,CAAC;IAC5B,eAAe,EAAE,MAAM,EAAE,CAAC;IAC1B,cAAc,EAAE,MAAM,EAAE,CAAC;IACzB,eAAe,EAAE,MAAM,CAAC;CACzB;AAED,MAAM,WAAW,cAAe,SAAQ,aAAa;IACnD,eAAe,EAAE,MAAM,CAAC;CACzB;AAED,MAAM,WAAW,UAAU,CAAC,CAAC;IAC3B,KAAK,EAAE,CAAC,CAAC;IACT,SAAS,EAAE,MAAM,CAAC;IAClB,GAAG,EAAE,MAAM,CAAC;CACb;AAID,MAAM,WAAW,YAAY;IAC3B,IAAI,EAAE,MAAM,CAAC;IACb,KAAK,EAAE,MAAM,CAAC;IACd,OAAO,EAAE,MAAM,CAAC;CACjB;AAED,MAAM,WAAW,UAAU;IACzB,SAAS,EAAE,MAAM,CAAC;IAClB,KAAK,EAAE,MAAM,CAAC;IACd,WAAW,EAAE,MAAM,CAAC;IACpB,cAAc,EAAE,MAAM,CAAC;IACvB,QAAQ,EAAE,YAAY,EAAE,CAAC;IACzB,YAAY,EAAE,MAAM,CAAC;CACtB;AAED,MAAM,WAAW,UAAU;IACzB,SAAS,EAAE,MAAM,CAAC;IAClB,UAAU,EAAE,MAAM,CAAC;IACnB,QAAQ,EAAE,YAAY,EAAE,CAAC;IACzB,GAAG,EAAE,MAAM,CAAC;CACb;AAED,MAAM,WAAW,eAAe;IAC9B,KAAK,EAAE,MAAM,CAAC;IACd,UAAU,EAAE,YAAY,GAAG,IAAI,CAAC;IAChC,UAAU,EAAE,YAAY,GAAG,IAAI,CAAC;CACjC;AAED,MAAM,WAAW,mBAAmB;IAClC,IAAI,EAAE,MAAM,CAAC;IACb,WAAW,EAAE,eAAe,EAAE,CAAC;IAC/B,SAAS,EAAE,MAAM,GAAG,IAAI,CAAC;IACzB,SAAS,EAAE,MAAM,GAAG,IAAI,CAAC;CAC1B;AAED,MAAM,WAAW,iBAAiB;IAChC,IAAI,EAAE,MAAM,CAAC;IACb,UAAU,CAAC,EAAE,MAAM,CAAC;IACpB,YAAY,CAAC,EAAE,MAAM,CAAC;IACtB,WAAW,EAAE,OAAO,CAAC;IACrB,WAAW,EAAE,OAAO,CAAC;IACrB,QAAQ,CAAC,EAAE,MAAM,CAAC;IAClB,aAAa,CAAC,EAAE,MAAM,CAAC;CACxB;AAED,MAAM,WAAW,sBAAsB;IACrC,SAAS,EAAE,MAAM,CAAC;IAClB,KAAK,EAAE,iBAAiB,EAAE,CAAC;CAC5B"}
1
+ {"version":3,"file":"types.d.ts","sourceRoot":"","sources":["../src/types.ts"],"names":[],"mappings":"AAAA,MAAM,WAAW,aAAa;IAC5B,IAAI,EAAE,MAAM,CAAC;IACb,KAAK,EAAE,MAAM,CAAC;IACd,OAAO,EAAE,MAAM,EAAE,CAAC;IAClB,OAAO,EAAE,MAAM,CAAC;IAChB,IAAI,EAAE,MAAM,CAAC;IACb,GAAG,EAAE,MAAM,CAAC;IACZ,gBAAgB,EAAE,MAAM,CAAC;CAC1B;AAED,MAAM,WAAW,eAAe;IAC9B,KAAK,EAAE,MAAM,CAAC;IACd,IAAI,EAAE,MAAM,CAAC;CACd;AAED,MAAM,WAAW,YAAY;IAC3B,IAAI,EAAE,MAAM,CAAC;IACb,KAAK,EAAE,MAAM,CAAC;IACd,OAAO,EAAE,MAAM,EAAE,CAAC;IAClB,OAAO,EAAE,MAAM,CAAC;IAChB,IAAI,EAAE,MAAM,CAAC;IACb,GAAG,EAAE,MAAM,CAAC;IACZ,MAAM,EAAE,MAAM,CAAC;IACf,KAAK,EAAE,MAAM,CAAC;IACd,KAAK,EAAE,MAAM,CAAC;IACd,iBAAiB,EAAE,eAAe,EAAE,CAAC;IACrC,QAAQ,EAAE,MAAM,EAAE,CAAC;IACnB,UAAU,EAAE,MAAM,EAAE,CAAC;IACrB,MAAM,EAAE,MAAM,CAAC;CAChB;AAED,MAAM,WAAW,eAAe;IAC9B,KAAK,EAAE,MAAM,CAAC;IACd,OAAO,EAAE,MAAM,CAAC;CACjB;AAED,MAAM,WAAW,cAAc;IAC7B,IAAI,EAAE,MAAM,CAAC;IACb,KAAK,EAAE,MAAM,CAAC;IACd,KAAK,EAAE,MAAM,CAAC;IACd,QAAQ,EAAE,eAAe,EAAE,CAAC;IAC5B,eAAe,EAAE,MAAM,EAAE,CAAC;IAC1B,cAAc,EAAE,MAAM,EAAE,CAAC;IACzB,eAAe,EAAE,MAAM,CAAC;CACzB;AAED,MAAM,WAAW,cAAe,SAAQ,aAAa;IACnD,eAAe,EAAE,MAAM,CAAC;CACzB;AAED,MAAM,WAAW,UAAU,CAAC,CAAC;IAC3B,KAAK,EAAE,CAAC,CAAC;IACT,SAAS,EAAE,MAAM,CAAC;IAClB,GAAG,EAAE,MAAM,CAAC;CACb;AAID,MAAM,WAAW,YAAY;IAC3B,IAAI,EAAE,MAAM,CAAC;IACb,KAAK,EAAE,MAAM,CAAC;IACd,OAAO,EAAE,MAAM,CAAC;CACjB;AAED,MAAM,WAAW,UAAU;IACzB,SAAS,EAAE,MAAM,CAAC;IAClB,KAAK,EAAE,MAAM,CAAC;IACd,WAAW,EAAE,MAAM,CAAC;IACpB,cAAc,EAAE,MAAM,CAAC;IACvB,QAAQ,EAAE,YAAY,EAAE,CAAC;IACzB,YAAY,EAAE,MAAM,CAAC;CACtB;AAED,MAAM,WAAW,UAAU;IACzB,SAAS,EAAE,MAAM,CAAC;IAClB,UAAU,EAAE,MAAM,CAAC;IACnB,QAAQ,EAAE,YAAY,EAAE,CAAC;IACzB,GAAG,EAAE,MAAM,CAAC;CACb;AAED,MAAM,WAAW,eAAe;IAC9B,KAAK,EAAE,MAAM,CAAC;IACd,UAAU,EAAE,YAAY,GAAG,IAAI,CAAC;IAChC,UAAU,EAAE,YAAY,GAAG,IAAI,CAAC;CACjC;AAED,MAAM,WAAW,mBAAmB;IAClC,IAAI,EAAE,MAAM,CAAC;IACb,WAAW,EAAE,eAAe,EAAE,CAAC;IAC/B,SAAS,EAAE,MAAM,GAAG,IAAI,CAAC;IACzB,SAAS,EAAE,MAAM,GAAG,IAAI,CAAC;CAC1B;AAED,MAAM,WAAW,iBAAiB;IAChC,IAAI,EAAE,MAAM,CAAC;IACb,UAAU,CAAC,EAAE,MAAM,CAAC;IACpB,YAAY,CAAC,EAAE,MAAM,CAAC;IACtB,WAAW,EAAE,OAAO,CAAC;IACrB,WAAW,EAAE,OAAO,CAAC;IACrB,QAAQ,CAAC,EAAE,MAAM,CAAC;IAClB,aAAa,CAAC,EAAE,MAAM,CAAC;CACxB;AAED,MAAM,WAAW,sBAAsB;IACrC,SAAS,EAAE,MAAM,CAAC;IAClB,KAAK,EAAE,iBAAiB,EAAE,CAAC;CAC5B;AAID,MAAM,WAAW,iBAAiB;IAChC,IAAI,EAAE,MAAM,CAAC;IACb,IAAI,EAAE,MAAM,CAAC;CACd;AAED,MAAM,WAAW,oBAAoB;IACnC,MAAM,EAAE,MAAM,CAAC;IACf,KAAK,EAAE,MAAM,CAAC;IACd,MAAM,EAAE,MAAM,CAAC;IACf,KAAK,EAAE,MAAM,CAAC;IACd,UAAU,EAAE,MAAM,EAAE,CAAC;IACrB,aAAa,EAAE,iBAAiB,EAAE,CAAC;IACnC,UAAU,EAAE,MAAM,GAAG,IAAI,CAAC;IAC1B,OAAO,EAAE,MAAM,CAAC;IAChB,UAAU,EAAE,MAAM,CAAC;IACnB,eAAe,EAAE,MAAM,CAAC;IACxB,UAAU,EAAE,MAAM,CAAC;IACnB,GAAG,EAAE,MAAM,CAAC;CACb;AAED,MAAM,WAAW,YAAY;IAC3B,OAAO,EAAE,MAAM,CAAC;IAChB,WAAW,EAAE,MAAM,CAAC;IACpB,UAAU,EAAE,MAAM,CAAC;CACpB;AAED,MAAM,WAAW,aAAa;IAC5B,KAAK,EAAE,MAAM,CAAC;IACd,IAAI,EAAE,MAAM,CAAC;IACb,WAAW,EAAE,MAAM,CAAC;IACpB,kBAAkB,EAAE,MAAM,EAAE,CAAC;CAC9B;AAED,MAAM,WAAW,WAAW;IAC1B,UAAU,EAAE,MAAM,CAAC;IACnB,kBAAkB,EAAE,MAAM,CAAC;IAC3B,eAAe,EAAE,MAAM,CAAC;IACxB,OAAO,EAAE,MAAM,CAAC;IAChB,UAAU,EAAE,MAAM,EAAE,CAAC;CACtB;AAED,MAAM,WAAW,mBAAoB,SAAQ,oBAAoB;IAC/D,cAAc,EAAE,MAAM,CAAC;IACvB,OAAO,EAAE,MAAM,CAAC;IAChB,WAAW,EAAE;QACX,QAAQ,EAAE,MAAM,CAAC;QACjB,MAAM,EAAE,MAAM,CAAC;QACf,WAAW,EAAE,MAAM,CAAC;QACpB,WAAW,EAAE,MAAM,CAAC;QACpB,kBAAkB,EAAE,MAAM,CAAC;KAC5B,CAAC;IACF,MAAM,EAAE,WAAW,CAAC;IACpB,IAAI,EAAE,aAAa,EAAE,CAAC;IACtB,gBAAgB,EAAE,YAAY,EAAE,CAAC;IACjC,kBAAkB,EAAE,YAAY,EAAE,CAAC;IACnC,eAAe,EAAE,MAAM,CAAC;IACxB,iBAAiB,EAAE,MAAM,CAAC;IAC1B,gBAAgB,EAAE,MAAM,EAAE,CAAC;IAC3B,GAAG,EAAE,MAAM,CAAC;CACb"}
package/package.json CHANGED
@@ -1,6 +1,6 @@
1
1
  {
2
2
  "name": "@pharmatools/pubcrawl",
3
- "version": "2.0.0",
3
+ "version": "2.1.1",
4
4
  "description": "MCP server for PubMed literature search and US/UK drug labelling — built by PharmaTools.AI",
5
5
  "mcpName": "io.github.nickjlamb/pubcrawl",
6
6
  "author": "PharmaTools.AI",
package/server.json CHANGED
@@ -1,7 +1,7 @@
1
1
  {
2
2
  "$schema": "https://static.modelcontextprotocol.io/schemas/2025-12-11/server.schema.json",
3
3
  "name": "io.github.nickjlamb/pubcrawl",
4
- "description": "MCP server for PubMed literature search and US/UK drug labelling. 10 tools: search PubMed, get abstracts, full text, related papers, citations, trending papers, US prescribing information (DailyMed), UK SmPC (eMC), compare US/UK labels, and search by indication (OpenFDA).",
4
+ "description": "PubMed literature search and US/UK drug labelling for AI assistants.",
5
5
  "repository": {
6
6
  "url": "https://github.com/nickjlamb/pubcrawl",
7
7
  "source": "github"