@molgenis/vip-report-template 6.1.1 → 7.0.0

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (285) hide show
  1. package/.nvmrc +1 -1
  2. package/.travis.yml +9 -11
  3. package/README.md +411 -1
  4. package/eslint.config.mjs +11 -0
  5. package/package.json +40 -35
  6. package/scripts/deploy_npm_registry.sh +5 -0
  7. package/src/App.tsx +35 -29
  8. package/src/assets/sass/main.scss +12 -4
  9. package/src/components/Allele.tsx +95 -0
  10. package/src/components/Anchor.tsx +1 -1
  11. package/src/components/Breadcrumb.tsx +8 -5
  12. package/src/components/DatasetDropdown.tsx +10 -23
  13. package/src/components/ErrorNotification.tsx +9 -0
  14. package/src/components/GenomeBrowser.tsx +40 -23
  15. package/src/components/HpoTerm.tsx +1 -1
  16. package/src/components/{record/Pager.tsx → Pager.tsx} +21 -14
  17. package/src/components/RecordsPerPage.tsx +9 -7
  18. package/src/components/RecordsTable.tsx +130 -0
  19. package/src/components/SampleTable.tsx +70 -98
  20. package/src/components/SearchBox.tsx +8 -2
  21. package/src/components/Sort.tsx +28 -25
  22. package/src/components/Table.tsx +16 -0
  23. package/src/components/Tooltip.tsx +20 -0
  24. package/src/components/VariantBreadcrumb.tsx +54 -0
  25. package/src/components/VariantConsequenceContainer.tsx +100 -0
  26. package/src/components/VariantConsequenceTable.tsx +58 -0
  27. package/src/components/VariantContainer.tsx +71 -0
  28. package/src/components/VariantFilters.tsx +27 -0
  29. package/src/components/VariantGenotypeTable.tsx +44 -0
  30. package/src/components/VariantInfoTable.tsx +24 -33
  31. package/src/components/VariantResults.tsx +103 -0
  32. package/src/components/VariantTable.tsx +62 -66
  33. package/src/components/VariantTypeSelect.tsx +34 -0
  34. package/src/components/VariantsContainer.tsx +150 -0
  35. package/src/components/VariantsContainerHeader.tsx +70 -0
  36. package/src/components/field/Field.tsx +80 -0
  37. package/src/components/field/FieldAlt.tsx +19 -0
  38. package/src/components/field/FieldChrom.tsx +6 -0
  39. package/src/components/{record/Id.tsx → field/FieldFilter.tsx} +2 -1
  40. package/src/components/field/FieldFormat.tsx +10 -0
  41. package/src/components/{record/Filter.tsx → field/FieldId.tsx} +1 -1
  42. package/src/components/field/FieldPos.tsx +6 -0
  43. package/src/components/field/FieldQual.tsx +6 -0
  44. package/src/components/field/FieldRef.tsx +8 -0
  45. package/src/components/field/composed/FieldClinVar.tsx +72 -0
  46. package/src/components/field/composed/FieldComposed.tsx +68 -0
  47. package/src/components/field/composed/FieldGene.tsx +39 -0
  48. package/src/components/field/composed/FieldGenotype.tsx +35 -0
  49. package/src/components/{record/format/GenotypeField.tsx → field/composed/FieldGenotypeSnvSv.tsx} +20 -16
  50. package/src/components/field/composed/FieldGenotypeStr.tsx +31 -0
  51. package/src/components/field/composed/FieldGnomAd.tsx +58 -0
  52. package/src/components/field/composed/FieldHpo.tsx +50 -0
  53. package/src/components/field/composed/FieldInheritanceModes.tsx +32 -0
  54. package/src/components/field/composed/FieldLocus.tsx +18 -0
  55. package/src/components/field/composed/FieldVipC.tsx +25 -0
  56. package/src/components/field/composed/FieldVipCS.tsx +15 -0
  57. package/src/components/field/composed/FieldVkgl.tsx +37 -0
  58. package/src/components/field/genotype/FieldGenotype.tsx +19 -0
  59. package/src/components/field/genotype/FieldGenotypeType.tsx +9 -0
  60. package/src/components/field/info/FieldConsequence.tsx +15 -0
  61. package/src/components/{record/info/Hgvs.tsx → field/info/FieldHgvs.tsx} +4 -6
  62. package/src/components/field/info/FieldInfo.tsx +27 -0
  63. package/src/components/{record/info/PubMed.tsx → field/info/FieldPubMed.tsx} +4 -7
  64. package/src/components/field/typed/FieldCategorical.tsx +17 -0
  65. package/src/components/{record/field/FieldValueCharacter.tsx → field/typed/FieldCharacter.tsx} +3 -2
  66. package/src/components/{record/field/FieldValueFlag.tsx → field/typed/FieldFlag.tsx} +3 -2
  67. package/src/components/{record/field/FieldValueFloat.tsx → field/typed/FieldFloat.tsx} +3 -2
  68. package/src/components/{record/field/FieldValueInteger.tsx → field/typed/FieldInteger.tsx} +3 -2
  69. package/src/components/{record/field/FieldValueString.tsx → field/typed/FieldString.tsx} +3 -2
  70. package/src/components/field/typed/FieldTyped.tsx +20 -0
  71. package/src/components/field/typed/FieldTypedItem.tsx +49 -0
  72. package/src/components/field/typed/FieldTypedMultiple.tsx +21 -0
  73. package/src/components/filter/Filter.tsx +56 -48
  74. package/src/components/filter/FilterWrapper.scss +23 -0
  75. package/src/components/filter/FilterWrapper.tsx +63 -0
  76. package/src/components/filter/composed/FilterAllelicImbalance.tsx +26 -0
  77. package/src/components/filter/composed/FilterComposed.tsx +92 -0
  78. package/src/components/filter/composed/FilterDeNovo.tsx +35 -0
  79. package/src/components/filter/composed/FilterHpo.tsx +16 -0
  80. package/src/components/filter/composed/FilterInheritance.tsx +42 -0
  81. package/src/components/filter/composed/FilterLocus.tsx +75 -0
  82. package/src/components/filter/composed/FilterVipC.tsx +16 -0
  83. package/src/components/filter/composed/FilterVipCS.tsx +16 -0
  84. package/src/components/filter/fixed/FilterAlt.tsx +20 -0
  85. package/src/components/filter/fixed/FilterChrom.tsx +22 -0
  86. package/src/components/filter/fixed/FilterFilter.tsx +20 -0
  87. package/src/components/filter/fixed/FilterFixed.tsx +96 -0
  88. package/src/components/filter/fixed/FilterId.tsx +20 -0
  89. package/src/components/filter/fixed/FilterPos.tsx +22 -0
  90. package/src/components/filter/fixed/FilterQual.tsx +21 -0
  91. package/src/components/filter/fixed/FilterRef.tsx +22 -0
  92. package/src/components/filter/typed/FilterCategorical.tsx +119 -0
  93. package/src/components/filter/typed/FilterFlag.tsx +23 -0
  94. package/src/components/filter/typed/FilterInterval.tsx +72 -0
  95. package/src/components/filter/typed/FilterString.tsx +43 -0
  96. package/src/components/filter/typed/FilterTyped.tsx +56 -0
  97. package/src/components/form/ButtonApply.tsx +11 -0
  98. package/src/components/form/ButtonDownload.tsx +11 -0
  99. package/src/components/form/ButtonReset.tsx +9 -0
  100. package/src/components/{Checkbox.tsx → form/Checkbox.tsx} +4 -9
  101. package/src/components/form/Input.tsx +19 -0
  102. package/src/components/form/Select.scss +7 -0
  103. package/src/components/form/Select.tsx +34 -0
  104. package/src/components/tree/DecisionTreeBoolMultiQuery.tsx +1 -1
  105. package/src/components/tree/DecisionTreeBoolQuery.tsx +1 -1
  106. package/src/components/tree/DecisionTreeNode.tsx +41 -39
  107. package/src/components/tree/DecisionTreeNodeBool.tsx +1 -1
  108. package/src/components/tree/DecisionTreeNodeBoolMulti.tsx +1 -1
  109. package/src/components/tree/DecisionTreeNodeCategorical.tsx +1 -1
  110. package/src/components/tree/DecisionTreeNodeExists.tsx +1 -1
  111. package/src/components/tree/DecisionTreeNodeLeaf.tsx +1 -1
  112. package/src/components/tree/DecisionTreeOutcomeNode.tsx +1 -1
  113. package/src/components/tree/DecisionTreePath.tsx +1 -1
  114. package/src/igv.d.ts +2 -1
  115. package/src/index.tsx +48 -19
  116. package/src/mocks/GRCh37/decisionTree.json +23 -22
  117. package/src/mocks/GRCh37/field_metadata.json +435 -95
  118. package/src/mocks/GRCh37/sampleTree.json +143 -0
  119. package/src/mocks/GRCh37/static.ts +63 -133
  120. package/src/mocks/GRCh37/vcf/family.vcf.blob +37 -31
  121. package/src/mocks/GRCh38/decisionTree.json +52 -33
  122. package/src/mocks/GRCh38/decisionTreeStr.json +572 -0
  123. package/src/mocks/GRCh38/fasta/chr1_149380406-149403321.fasta.gz.blob +0 -0
  124. package/src/mocks/GRCh38/field_metadata.json +435 -95
  125. package/src/mocks/GRCh38/sampleTree.json +175 -0
  126. package/src/mocks/GRCh38/static.ts +101 -42
  127. package/src/mocks/GRCh38/str.cram.blob +0 -0
  128. package/src/mocks/GRCh38/str.cram.crai.blob +0 -0
  129. package/src/mocks/GRCh38/vcf/family.vcf.blob +25 -24
  130. package/src/mocks/GRCh38/vcf/no_vep.vcf.blob +29 -28
  131. package/src/mocks/GRCh38/vcf/samples_0.vcf.blob +28 -27
  132. package/src/mocks/GRCh38/vcf/samples_1.vcf.blob +29 -28
  133. package/src/mocks/GRCh38/vcf/samples_100.vcf.blob +28 -27
  134. package/src/mocks/GRCh38/vcf/str.vcf.blob +321 -0
  135. package/src/mocks/MockApiClient.ts +341 -328
  136. package/src/mocks/config_cram.json +701 -0
  137. package/src/mocks/config_vcf.json +699 -0
  138. package/src/store/app.ts +30 -0
  139. package/src/store/index.tsx +3 -168
  140. package/src/store/variants.ts +182 -0
  141. package/src/types/config.d.ts +190 -0
  142. package/src/types/configCellComposed.d.ts +86 -0
  143. package/src/types/configCells.d.ts +129 -0
  144. package/src/types/configFilter.d.ts +80 -0
  145. package/src/types/configFilterComposed.d.ts +60 -0
  146. package/src/types/configSort.d.ts +13 -0
  147. package/src/types/filter.d.ts +17 -0
  148. package/src/types/store.d.ts +34 -0
  149. package/src/utils/api.ts +281 -0
  150. package/src/utils/config/config.ts +182 -0
  151. package/src/utils/config/configCells.ts +74 -0
  152. package/src/utils/config/configCellsComposed.ts +508 -0
  153. package/src/utils/config/configCellsField.ts +61 -0
  154. package/src/utils/config/configCellsFixed.ts +126 -0
  155. package/src/utils/config/configFilters.ts +46 -0
  156. package/src/utils/config/configFiltersComposed.ts +208 -0
  157. package/src/utils/config/configFiltersField.ts +49 -0
  158. package/src/utils/config/configFiltersFixed.ts +106 -0
  159. package/src/utils/config/configSorts.ts +44 -0
  160. package/src/utils/config/configValidator.ts +380 -0
  161. package/src/utils/config/configVip.ts +25 -0
  162. package/src/utils/csq.ts +115 -0
  163. package/src/utils/decisionTree.ts +45 -0
  164. package/src/utils/download.ts +30 -0
  165. package/src/utils/error.ts +69 -0
  166. package/src/utils/query/query.ts +55 -0
  167. package/src/utils/query/queryFilter.ts +132 -0
  168. package/src/utils/query/queryFilterComposed.ts +247 -0
  169. package/src/utils/query/queryFilterField.ts +75 -0
  170. package/src/utils/query/queryFilterFixed.ts +44 -0
  171. package/src/utils/query/querySample.ts +18 -0
  172. package/src/utils/query/queryVariantType.ts +76 -0
  173. package/src/utils/query/selector.ts +41 -0
  174. package/src/utils/{sortUtils.ts → query/sort.ts} +32 -11
  175. package/src/utils/sample.ts +19 -35
  176. package/src/utils/utils.ts +66 -2
  177. package/src/utils/variantType.ts +43 -0
  178. package/src/utils/vcf.ts +352 -0
  179. package/src/views/Help.tsx +109 -114
  180. package/src/views/Home.tsx +3 -2
  181. package/src/views/Sample.tsx +12 -7
  182. package/src/views/SampleVariant.tsx +23 -112
  183. package/src/views/SampleVariantConsequence.tsx +54 -114
  184. package/src/views/SampleVariants.tsx +33 -445
  185. package/src/views/SampleVariantsRedirect.tsx +20 -0
  186. package/src/views/Samples.tsx +7 -10
  187. package/src/views/Variant.tsx +31 -61
  188. package/src/views/VariantConsequence.tsx +42 -72
  189. package/src/views/Variants.tsx +29 -138
  190. package/src/views/VariantsRedirect.tsx +25 -0
  191. package/src/views/data/data.tsx +32 -6
  192. package/tests/store/variants.test.ts +122 -0
  193. package/tests/utils/config/config.test.ts +167 -0
  194. package/tests/utils/config/configCells.test.ts +86 -0
  195. package/tests/utils/config/configCellsComposed.test.ts +1163 -0
  196. package/tests/utils/config/configCellsField.test.ts +164 -0
  197. package/tests/utils/config/configCellsFixed.test.ts +99 -0
  198. package/tests/utils/config/configFilters.test.ts +80 -0
  199. package/tests/utils/config/configFiltersComposed.test.ts +504 -0
  200. package/tests/utils/config/configFiltersField.test.ts +140 -0
  201. package/tests/utils/config/configFiltersFixed.test.ts +81 -0
  202. package/tests/utils/config/configSorts.test.ts +55 -0
  203. package/tests/utils/config/configValidator.test.ts +56 -0
  204. package/tests/utils/config/configVip.test.ts +53 -0
  205. package/tests/utils/decisionTree.test.ts +71 -0
  206. package/tests/utils/download.test.ts +20 -0
  207. package/tests/utils/query/query.test.ts +84 -0
  208. package/tests/utils/query/queryFilter.test.ts +243 -0
  209. package/tests/utils/query/queryFilterComposed.test.ts +301 -0
  210. package/tests/utils/query/queryFilterField.test.ts +75 -0
  211. package/tests/utils/query/queryFilterFixed.test.ts +86 -0
  212. package/tests/utils/query/querySample.test.ts +45 -0
  213. package/tests/utils/query/queryVariantType.test.ts +56 -0
  214. package/{src/__tests__/sortUtils.test.ts → tests/utils/query/sort.test.ts} +3 -4
  215. package/tests/utils/sample.test.ts +259 -0
  216. package/tests/utils/utils.test.ts +120 -0
  217. package/tests/utils/variantType.test.ts +48 -0
  218. package/tests/utils/vcf.test.ts +649 -0
  219. package/tsconfig.json +6 -2
  220. package/vite.config.mts +20 -3
  221. package/.eslintignore +0 -4
  222. package/.eslintrc.js +0 -23
  223. package/src/Api.ts +0 -12
  224. package/src/__tests__/decisionTreeUtils.test.ts +0 -75
  225. package/src/__tests__/field.test.ts +0 -107
  226. package/src/__tests__/query.test.ts +0 -188
  227. package/src/__tests__/sample.test.ts +0 -184
  228. package/src/__tests__/utils.test.ts +0 -24
  229. package/src/__tests__/viewUtils.test.ts +0 -125
  230. package/src/components/ConsequenceTable.tsx +0 -45
  231. package/src/components/Error.tsx +0 -9
  232. package/src/components/FieldHeader.tsx +0 -26
  233. package/src/components/InfoCollapsablePane.tsx +0 -90
  234. package/src/components/VariantInfoNestedTable.tsx +0 -127
  235. package/src/components/VariantSampleTable.tsx +0 -58
  236. package/src/components/VariantsSampleTable.tsx +0 -183
  237. package/src/components/VariantsTable.tsx +0 -124
  238. package/src/components/filter/FilterAllelicBalance.tsx +0 -81
  239. package/src/components/filter/FilterCategorical.tsx +0 -81
  240. package/src/components/filter/FilterClinVar.tsx +0 -21
  241. package/src/components/filter/FilterGene.tsx +0 -34
  242. package/src/components/filter/FilterHpo.tsx +0 -161
  243. package/src/components/filter/FilterInheritance.tsx +0 -162
  244. package/src/components/filter/FilterIntegerGq.tsx +0 -47
  245. package/src/components/filter/FilterVI.tsx +0 -68
  246. package/src/components/filter/FilterVariantType.tsx +0 -146
  247. package/src/components/filter/Filters.tsx +0 -29
  248. package/src/components/filter/InfoFilter.tsx +0 -39
  249. package/src/components/filter/InfoFilters.tsx +0 -35
  250. package/src/components/filter/SampleFilters.tsx +0 -93
  251. package/src/components/filter/SamplesFilters.tsx +0 -33
  252. package/src/components/record/Allele.tsx +0 -38
  253. package/src/components/record/AlleleBreakend.tsx +0 -5
  254. package/src/components/record/AlleleMissing.tsx +0 -5
  255. package/src/components/record/AlleleNucs.tsx +0 -49
  256. package/src/components/record/AlleleSymbolic.tsx +0 -5
  257. package/src/components/record/Alt.tsx +0 -17
  258. package/src/components/record/Chrom.tsx +0 -5
  259. package/src/components/record/Format.tsx +0 -40
  260. package/src/components/record/Info.tsx +0 -55
  261. package/src/components/record/Pos.tsx +0 -5
  262. package/src/components/record/Qual.tsx +0 -5
  263. package/src/components/record/RecordDownload.tsx +0 -66
  264. package/src/components/record/Ref.tsx +0 -6
  265. package/src/components/record/field/Field.tsx +0 -36
  266. package/src/components/record/field/FieldMultipleValue.tsx +0 -22
  267. package/src/components/record/field/FieldSingleValue.tsx +0 -35
  268. package/src/components/record/info/ClinVar.tsx +0 -81
  269. package/src/components/record/info/Consequence.tsx +0 -18
  270. package/src/components/record/info/Gene.tsx +0 -56
  271. package/src/components/record/info/GnomAD.tsx +0 -54
  272. package/src/components/record/info/Hpo.tsx +0 -52
  273. package/src/components/record/info/InheritanceModes.tsx +0 -22
  274. package/src/components/record/info/VipC.tsx +0 -23
  275. package/src/components/record/info/Vkgl.tsx +0 -42
  276. package/src/mocks/GRCh37/vcf/no_vep.vcf.blob +0 -61
  277. package/src/mocks/GRCh37/vcf/samples_0.vcf.blob +0 -93
  278. package/src/mocks/GRCh37/vcf/samples_1.vcf.blob +0 -93
  279. package/src/mocks/GRCh37/vcf/samples_100.vcf.blob +0 -93
  280. package/src/utils/ApiUtils.ts +0 -259
  281. package/src/utils/csqUtils.ts +0 -27
  282. package/src/utils/decisionTreeUtils.ts +0 -14
  283. package/src/utils/field.ts +0 -49
  284. package/src/utils/query.ts +0 -154
  285. package/src/utils/viewUtils.ts +0 -32
package/src/index.tsx CHANGED
@@ -7,33 +7,38 @@ import App from "./App";
7
7
  import { dom, library } from "@fortawesome/fontawesome-svg-core";
8
8
  import {
9
9
  faAngleDown,
10
+ faAngleRight,
10
11
  faAngleUp,
11
12
  faCircleExclamation,
12
- faCircleXmark,
13
13
  faCircleInfo,
14
14
  faCircleQuestion,
15
+ faCircleXmark,
15
16
  faDownload,
16
17
  faExternalLink,
17
18
  faHome,
19
+ faInfo,
18
20
  faSearch,
19
21
  } from "@fortawesome/free-solid-svg-icons";
20
22
  import { Provider } from "./store";
21
- import { ErrorBoundary } from "solid-js";
22
- import { Error } from "./components/Error";
23
+ import { createSignal, ErrorBoundary, Show } from "solid-js";
23
24
  import { HashRouter, Route } from "@solidjs/router";
24
25
  import { Home } from "./views/Home";
25
26
  import { Samples } from "./views/Samples";
26
27
  import { Sample } from "./views/Sample";
27
- import { SampleVariantsView } from "./views/SampleVariants";
28
- import { SampleVariantView } from "./views/SampleVariant";
29
- import { SampleVariantConsequenceView } from "./views/SampleVariantConsequence";
30
- import { VariantsView } from "./views/Variants";
28
+ import { SampleVariant } from "./views/SampleVariant";
29
+ import { SampleVariantConsequence } from "./views/SampleVariantConsequence";
30
+ import { VariantsRedirect } from "./views/VariantsRedirect.tsx";
31
31
  import { Variant } from "./views/Variant";
32
32
  import { VariantConsequence } from "./views/VariantConsequence";
33
33
  import { Help } from "./views/Help";
34
+ import { SampleVariants } from "./views/SampleVariants.tsx";
35
+ import { SampleVariantsRedirect } from "./views/SampleVariantsRedirect.tsx";
36
+ import { Variants } from "./views/Variants.tsx";
37
+ import { ErrorNotification } from "./components/ErrorNotification.tsx";
34
38
 
35
39
  library.add(
36
40
  faAngleDown,
41
+ faAngleRight,
37
42
  faAngleUp,
38
43
  faCircleExclamation,
39
44
  faCircleXmark,
@@ -42,6 +47,7 @@ library.add(
42
47
  faDownload,
43
48
  faExternalLink,
44
49
  faHome,
50
+ faInfo,
45
51
  faSearch,
46
52
  );
47
53
 
@@ -50,16 +56,29 @@ function processIcons() {
50
56
  dom.watch();
51
57
  }
52
58
 
53
- if (document.readyState === "complete") {
59
+ // process icons if document state is "complete" or "interactive", list for event if "loading"
60
+ if (document.readyState !== "loading") {
54
61
  processIcons();
55
62
  } else {
56
63
  window.addEventListener("DOMContentLoaded", processIcons);
57
64
  }
58
65
 
66
+ const [error, setError] = createSignal<unknown>();
67
+ window.addEventListener("error", function () {
68
+ setError({ message: "An unexpected error occurred" });
69
+ });
70
+
71
+ window.addEventListener("unhandledrejection", function () {
72
+ setError({ message: "An unexpected error occurred" });
73
+ });
74
+
59
75
  render(
60
76
  () => (
61
77
  <Provider>
62
- <ErrorBoundary fallback={(err) => <Error error={err as unknown} />}>
78
+ <Show when={error() !== undefined}>
79
+ <ErrorNotification error={error()} />
80
+ </Show>
81
+ <ErrorBoundary fallback={(err) => <ErrorNotification error={err} />}>
63
82
  <HashRouter root={App}>
64
83
  <Route path="/" component={Home} />
65
84
  <Route path="/samples">
@@ -67,22 +86,32 @@ render(
67
86
  <Route path="/:sampleId">
68
87
  <Route path="/" component={Sample} />
69
88
  <Route path="/variants">
70
- <Route path="/" component={SampleVariantsView} />
71
- <Route path="/:variantId">
72
- <Route path="/" component={SampleVariantView} />
73
- <Route path="/consequences">
74
- <Route path="/:consequenceId" component={SampleVariantConsequenceView} />
89
+ <Route path="/" component={SampleVariantsRedirect} />
90
+ <Route path="/:variantType">
91
+ <Route path="/" component={SampleVariants} />
92
+ <Route path="/variant">
93
+ <Route path="/:variantId">
94
+ <Route path="/" component={SampleVariant} />
95
+ <Route path="/consequences">
96
+ <Route path="/:consequenceId" component={SampleVariantConsequence} />
97
+ </Route>
98
+ </Route>
75
99
  </Route>
76
100
  </Route>
77
101
  </Route>
78
102
  </Route>
79
103
  </Route>
80
104
  <Route path="/variants">
81
- <Route path="/" component={VariantsView} />
82
- <Route path="/:variantId">
83
- <Route path="/" component={Variant} />
84
- <Route path="/consequences">
85
- <Route path="/:consequenceId" component={VariantConsequence} />
105
+ <Route path="/" component={VariantsRedirect} />
106
+ <Route path="/:variantType">
107
+ <Route path="/" component={Variants} />
108
+ <Route path="/variant">
109
+ <Route path="/:variantId">
110
+ <Route path="/" component={Variant} />
111
+ <Route path="/consequences">
112
+ <Route path="/:consequenceId" component={VariantConsequence} />
113
+ </Route>
114
+ </Route>
86
115
  </Route>
87
116
  </Route>
88
117
  </Route>
@@ -2,14 +2,13 @@
2
2
  "rootNode": "filter",
3
3
  "nodes": {
4
4
  "filter": {
5
+ "label": "filter",
5
6
  "type": "BOOL",
6
7
  "description": "All filters passed",
7
8
  "query": {
8
9
  "field": "FILTER",
9
10
  "operator": "==",
10
- "value": [
11
- "PASS"
12
- ]
11
+ "value": ["PASS"]
13
12
  },
14
13
  "outcomeTrue": {
15
14
  "nextNode": "vkgl"
@@ -22,6 +21,7 @@
22
21
  }
23
22
  },
24
23
  "spliceAI": {
24
+ "label": "spliceAI",
25
25
  "type": "BOOL_MULTI",
26
26
  "fields": [
27
27
  "INFO/CSQ/SpliceAI_pred_DS_AG",
@@ -67,6 +67,7 @@
67
67
  }
68
68
  },
69
69
  "vkgl": {
70
+ "label": "VKGL",
70
71
  "type": "CATEGORICAL",
71
72
  "description": "VKGL classification",
72
73
  "field": "INFO/CSQ/VKGL_CL",
@@ -92,6 +93,7 @@
92
93
  }
93
94
  },
94
95
  "annotSV": {
96
+ "label": "AnnotSV",
95
97
  "type": "CATEGORICAL",
96
98
  "description": "VKGL classification",
97
99
  "field": "INFO/CSQ/ASV_ACMG_class",
@@ -117,12 +119,10 @@
117
119
  }
118
120
  },
119
121
  "gnomad": {
122
+ "label": "GnomAD",
120
123
  "type": "BOOL_MULTI",
121
124
  "description": "gnomAD_AF < 0.02 && gnomAD_HN < 5",
122
- "fields": [
123
- "INFO/CSQ/gnomAD_AF",
124
- "INFO/CSQ/gnomAD_HN"
125
- ],
125
+ "fields": ["INFO/CSQ/gnomAD_AF", "INFO/CSQ/gnomAD_HN"],
126
126
  "outcomes": [
127
127
  {
128
128
  "operator": "OR",
@@ -151,6 +151,7 @@
151
151
  }
152
152
  },
153
153
  "effect": {
154
+ "label": "Effect",
154
155
  "type": "BOOL",
155
156
  "description": "Consequence contains 'missense'",
156
157
  "query": {
@@ -169,10 +170,9 @@
169
170
  }
170
171
  },
171
172
  "clinVar": {
173
+ "label": "ClinVar",
172
174
  "type": "BOOL_MULTI",
173
- "fields": [
174
- "INFO/CSQ/CLIN_SIG"
175
- ],
175
+ "fields": ["INFO/CSQ/CLIN_SIG"],
176
176
  "outcomes": [
177
177
  {
178
178
  "queries": [
@@ -195,10 +195,7 @@
195
195
  {
196
196
  "field": "INFO/CSQ/CLIN_SIG",
197
197
  "operator": "contains_any",
198
- "value": [
199
- "likely_benign",
200
- "benign"
201
- ]
198
+ "value": ["likely_benign", "benign"]
202
199
  }
203
200
  ],
204
201
  "outcomeTrue": {
@@ -210,10 +207,7 @@
210
207
  {
211
208
  "field": "INFO/CSQ/CLIN_SIG",
212
209
  "operator": "contains_any",
213
- "value": [
214
- "likely_pathogenic",
215
- "pathogenic"
216
- ]
210
+ "value": ["likely_pathogenic", "pathogenic"]
217
211
  }
218
212
  ],
219
213
  "outcomeTrue": {
@@ -229,6 +223,7 @@
229
223
  }
230
224
  },
231
225
  "sift": {
226
+ "label": "SIFT",
232
227
  "description": "SIFT qualitative prediction",
233
228
  "type": "BOOL",
234
229
  "query": {
@@ -247,11 +242,10 @@
247
242
  }
248
243
  },
249
244
  "polyphen": {
245
+ "label": "PolyPhen",
250
246
  "description": "PolyPhen qualitative prediction",
251
247
  "type": "BOOL_MULTI",
252
- "fields": [
253
- "INFO/CSQ/PolyPhen"
254
- ],
248
+ "fields": ["INFO/CSQ/PolyPhen"],
255
249
  "outcomes": [
256
250
  {
257
251
  "queries": [
@@ -304,6 +298,7 @@
304
298
  }
305
299
  },
306
300
  "impact": {
301
+ "label": "IMPACT",
307
302
  "type": "CATEGORICAL",
308
303
  "description": "IMPACT rating",
309
304
  "field": "INFO/CSQ/IMPACT",
@@ -325,28 +320,34 @@
325
320
  "nextNode": "exit_vus"
326
321
  }
327
322
  },
328
- "exit_lq": {
323
+ "exit_rm": {
324
+ "label": "Remove",
329
325
  "description": "Low quality variants.",
330
326
  "type": "LEAF",
331
327
  "class": "LQ"
332
328
  },
333
329
  "exit_b": {
330
+ "label": "Benign",
334
331
  "type": "LEAF",
335
332
  "class": "B"
336
333
  },
337
334
  "exit_lb": {
335
+ "label": "Likely Benign",
338
336
  "type": "LEAF",
339
337
  "class": "LB"
340
338
  },
341
339
  "exit_vus": {
340
+ "label": "Unknown Significance",
342
341
  "type": "LEAF",
343
342
  "class": "VUS"
344
343
  },
345
344
  "exit_lp": {
345
+ "label": "Likely Pathogenic",
346
346
  "type": "LEAF",
347
347
  "class": "LP"
348
348
  },
349
349
  "exit_p": {
350
+ "label": "Pathogenic",
350
351
  "type": "LEAF",
351
352
  "class": "P"
352
353
  }