@mcpassure/mcp-anvisa-bulario 0.0.1 → 2.0.0

package/dist/prompts/handlers.js

@@ -0,0 +1,267 @@
+const DISCLAIMER = "\n\n⚠️ **Aviso ANVISA:** Informações de consulta oficial. Decisões clínicas ou regulatórias " +
+    "devem ser baseadas na fonte ANVISA atualizada. Medicamentos sob Tarja Preta estão sujeitos " +
+    "à Portaria 344/98 — controle especial obrigatório.";
+export async function handleVerificarMedicamentoCompleto(input, repository) {
+    const { termo, incluir_apresentacoes, incluir_bula } = input;
+    let medicamentos = [];
+    let fonteUsada = "";
+    try {
+        const result = await repository.searchByName({ nome: termo, count: 5 });
+        medicamentos = result.data;
+        fonteUsada = "buscar_por_nome";
+    }
+    catch {
+        try {
+            const result = await repository.searchByPrincipalAtivo({ principioAtivo: termo, count: 5 });
+            medicamentos = result.data;
+            fonteUsada = "buscar_por_principio_ativo";
+        }
+        catch (err) {
+            const message = err instanceof Error ? err.message : String(err);
+            return [
+                {
+                    role: "assistant",
+                    content: {
+                        type: "text",
+                        text: `Não foi possível localizar medicamentos para o termo "${termo}": ${message}${DISCLAIMER}`,
+                    },
+                },
+            ];
+        }
+    }
+    if (medicamentos.length === 0) {
+        return [
+            {
+                role: "assistant",
+                content: {
+                    type: "text",
+                    text: `Nenhum medicamento encontrado para o termo "${termo}" no Bulário ANVISA.${DISCLAIMER}`,
+                },
+            },
+        ];
+    }
+    const sections = [
+        `## Medicamentos encontrados para "${termo}" (via ${fonteUsada})`,
+        `Total de resultados: ${medicamentos.length}`,
+    ];
+    for (const med of medicamentos) {
+        const linhas = [
+            `\n### ${med.nomeProduto}`,
+            `- **Empresa:** ${med.empresa}`,
+            `- **Nº Processo ANVISA:** ${med.numProcesso}`,
+        ];
+        if (med.dataAtualizacao)
+            linhas.push(`- **Última atualização:** ${med.dataAtualizacao}`);
+        if (incluir_apresentacoes && med.numProcesso) {
+            try {
+                const ap = await repository.getApresentacoes(med.numProcesso);
+                if (ap.data.length > 0) {
+                    linhas.push(`- **Apresentações (${ap.data.length}):**`);
+                    for (const a of ap.data.slice(0, 5)) {
+                        linhas.push(`  - ${a.descricao}`);
+                    }
+                    if (ap.data.length > 5)
+                        linhas.push(`  - ... (+${ap.data.length - 5} apresentações)`);
+                }
+            }
+            catch {
+                linhas.push(`- **Apresentações:** não disponível`);
+            }
+        }
+        if (incluir_bula && med.idBulaPacienteProtegido) {
+            try {
+                const bula = await repository.getBulaLink(med.idBulaPacienteProtegido);
+                if (bula.data.urlPdf) {
+                    linhas.push(`- **Bula (paciente):** ${bula.data.urlPdf}`);
+                }
+            }
+            catch {
+                linhas.push(`- **Bula:** não disponível`);
+            }
+        }
+        sections.push(linhas.join("\n"));
+    }
+    sections.push(DISCLAIMER);
+    return [
+        {
+            role: "user",
+            content: { type: "text", text: `Verificar medicamento: ${termo}` },
+        },
+        {
+            role: "assistant",
+            content: { type: "text", text: sections.join("\n") },
+        },
+    ];
+}
+export async function handleCompararTarjasPorClasse(input, repository) {
+    const { classe_terapeutica, limite } = input;
+    let medicamentos = [];
+    try {
+        const result = await repository.searchByClasseTerapeutica({
+            classeTerapeutica: classe_terapeutica,
+            count: limite,
+        });
+        medicamentos = result.data;
+    }
+    catch (err) {
+        const message = err instanceof Error ? err.message : String(err);
+        return [
+            {
+                role: "assistant",
+                content: {
+                    type: "text",
+                    text: `Erro ao buscar classe terapêutica "${classe_terapeutica}": ${message}${DISCLAIMER}`,
+                },
+            },
+        ];
+    }
+    const grupos = {
+        LIVRE: [],
+        VERMELHA: [],
+        PRETA: [],
+        DESCONHECIDA: [],
+    };
+    for (const med of medicamentos) {
+        if (med.numProcesso) {
+            try {
+                const det = await repository.getDetalhes(med.numProcesso);
+                const tarja = det.data.tarja ?? "DESCONHECIDA";
+                const grupo = tarja in grupos ? tarja : "DESCONHECIDA";
+                grupos[grupo].push(med.nomeProduto);
+            }
+            catch {
+                grupos.DESCONHECIDA.push(med.nomeProduto);
+            }
+        }
+    }
+    const total = medicamentos.length;
+    const lines = [
+        `## Classe Terapêutica: ${classe_terapeutica}`,
+        `**Total analisado:** ${total} medicamento(s)`,
+        "",
+        `- **Sem Tarja (Venda Livre):** ${grupos.LIVRE.length}`,
+        `- **Tarja Amarela (controle leve/antibióticos):** — *não categorizado pelo Bulário ANVISA*`,
+        `- **Tarja Vermelha (prescrição obrigatória):** ${grupos.VERMELHA.length}`,
+        `- **Tarja Preta (controle especial — Portaria 344/98):** ${grupos.PRETA.length}`,
+        `- **Não categorizado:** ${grupos.DESCONHECIDA.length}`,
+    ];
+    if (grupos.PRETA.length > 0) {
+        lines.push("", `⚠️ **Tarja Preta identificados (${grupos.PRETA.length}):** ${grupos.PRETA.slice(0, 10).join(", ")}`);
+    }
+    lines.push(DISCLAIMER);
+    return [
+        {
+            role: "user",
+            content: {
+                type: "text",
+                text: `Comparar tarjas para classe terapêutica: ${classe_terapeutica}`,
+            },
+        },
+        {
+            role: "assistant",
+            content: { type: "text", text: lines.join("\n") },
+        },
+    ];
+}
+export async function handleAnalisarApresentacoes(input, repository) {
+    const { nome_medicamento, agrupar_por } = input;
+    let medicamentos = [];
+    try {
+        const result = await repository.searchByName({ nome: nome_medicamento, count: 10 });
+        medicamentos = result.data;
+    }
+    catch (err) {
+        const message = err instanceof Error ? err.message : String(err);
+        return [
+            {
+                role: "assistant",
+                content: {
+                    type: "text",
+                    text: `Erro ao buscar "${nome_medicamento}": ${message}${DISCLAIMER}`,
+                },
+            },
+        ];
+    }
+    if (medicamentos.length === 0) {
+        return [
+            {
+                role: "assistant",
+                content: {
+                    type: "text",
+                    text: `Nenhum medicamento encontrado para "${nome_medicamento}".${DISCLAIMER}`,
+                },
+            },
+        ];
+    }
+    const agrupado = {};
+    for (const med of medicamentos.slice(0, 5)) {
+        if (!med.numProcesso)
+            continue;
+        try {
+            const apResult = await repository.getApresentacoes(med.numProcesso);
+            for (const ap of apResult.data) {
+                let chave = "Outros";
+                const desc = ap.descricao ?? "";
+                if (agrupar_por === "concentracao") {
+                    const match = desc.match(/\d+[\s,.]?\d*\s*(mg|mcg|g|ml|%|UI|mEq)/i);
+                    chave = match ? match[0].trim() : "Concentração não identificada";
+                }
+                else if (agrupar_por === "forma_farmaceutica") {
+                    const formas = [
+                        "comprimido",
+                        "cápsula",
+                        "xarope",
+                        "solução",
+                        "injetável",
+                        "pomada",
+                        "gel",
+                        "spray",
+                        "supositório",
+                        "adesivo",
+                    ];
+                    const forma = formas.find((f) => desc.toLowerCase().includes(f));
+                    chave = forma ? forma.charAt(0).toUpperCase() + forma.slice(1) : "Forma não identificada";
+                }
+                else if (agrupar_por === "fabricante") {
+                    chave = med.empresa ?? "Fabricante desconhecido";
+                }
+                if (!agrupado[chave])
+                    agrupado[chave] = [];
+                agrupado[chave].push(`${med.nomeProduto} — ${desc}`);
+            }
+        }
+        catch {
+            // ignora erros individuais de apresentações
+        }
+    }
+    const totalApresentacoes = Object.values(agrupado).flat().length;
+    const lines = [
+        `## Apresentações de "${nome_medicamento}" agrupadas por ${agrupar_por}`,
+        `**Total de apresentações analisadas:** ${totalApresentacoes}`,
+        "",
+    ];
+    for (const [grupo, items] of Object.entries(agrupado).sort()) {
+        lines.push(`### ${grupo} (${items.length})`);
+        for (const item of items.slice(0, 5)) {
+            lines.push(`- ${item}`);
+        }
+        if (items.length > 5)
+            lines.push(`- ... (+${items.length - 5} itens)`);
+        lines.push("");
+    }
+    lines.push(DISCLAIMER);
+    return [
+        {
+            role: "user",
+            content: {
+                type: "text",
+                text: `Analisar apresentações de ${nome_medicamento} agrupando por ${agrupar_por}`,
+            },
+        },
+        {
+            role: "assistant",
+            content: { type: "text", text: lines.join("\n") },
+        },
+    ];
+}
+//# sourceMappingURL=handlers.js.map

package/dist/prompts/handlers.js.map

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package/dist/prompts/index.d.ts

@@ -0,0 +1,4 @@
+import type { McpServer } from "@modelcontextprotocol/sdk/server/mcp.js";
+import type { IBularioRepository } from "../domain/repository.js";
+export declare function registerPrompts(server: McpServer, repository: IBularioRepository): void;
+//# sourceMappingURL=index.d.ts.map

package/dist/prompts/index.d.ts.map

@@ -0,0 +1 @@
+{"version":3,"file":"index.d.ts","sourceRoot":"","sources":["../../src/prompts/index.ts"],"names":[],"mappings":"AAAA,OAAO,KAAK,EAAE,SAAS,EAAE,MAAM,yCAAyC,CAAC;AACzE,OAAO,KAAK,EAAE,kBAAkB,EAAE,MAAM,yBAAyB,CAAC;AAYlE,wBAAgB,eAAe,CAAC,MAAM,EAAE,SAAS,EAAE,UAAU,EAAE,kBAAkB,GAAG,IAAI,CAgDvF"}

package/dist/prompts/index.js

@@ -0,0 +1,35 @@
+import { handleAnalisarApresentacoes, handleCompararTarjasPorClasse, handleVerificarMedicamentoCompleto, } from "./handlers.js";
+import { AnalisarApresentacoesInput, CompararTarjasPorClasseInput, VerificarMedicamentoCompletoInput, } from "./schemas.js";
+export function registerPrompts(server, repository) {
+    server.registerPrompt("verificar_medicamento_completo", {
+        title: "Verificar Medicamento Completo",
+        description: "Consolida nome, princípio ativo, classe terapêutica, tarja, apresentações e (opcional) bula " +
+            "para um termo de busca. Tenta busca por nome e fallback por princípio ativo.",
+        argsSchema: VerificarMedicamentoCompletoInput.shape,
+    }, async (args) => {
+        const parsed = VerificarMedicamentoCompletoInput.parse(args);
+        const messages = await handleVerificarMedicamentoCompleto(parsed, repository);
+        return { messages };
+    });
+    server.registerPrompt("comparar_tarjas_por_classe", {
+        title: "Comparar Tarjas por Classe Terapêutica",
+        description: "Agrupa medicamentos de uma classe terapêutica por tarja regulatória. " +
+            "Útil para entender o perfil de prescrição e controle de uma classe.",
+        argsSchema: CompararTarjasPorClasseInput.shape,
+    }, async (args) => {
+        const parsed = CompararTarjasPorClasseInput.parse(args);
+        const messages = await handleCompararTarjasPorClasse(parsed, repository);
+        return { messages };
+    });
+    server.registerPrompt("analisar_apresentacoes", {
+        title: "Analisar Apresentações de Medicamento",
+        description: "Agrupa as apresentações comerciais de um medicamento por concentração, " +
+            "forma farmacêutica ou fabricante.",
+        argsSchema: AnalisarApresentacoesInput.shape,
+    }, async (args) => {
+        const parsed = AnalisarApresentacoesInput.parse(args);
+        const messages = await handleAnalisarApresentacoes(parsed, repository);
+        return { messages };
+    });
+}
+//# sourceMappingURL=index.js.map

package/dist/prompts/index.js.map

@@ -0,0 +1 @@
+{"version":3,"file":"index.js","sourceRoot":"","sources":["../../src/prompts/index.ts"],"names":[],"mappings":"AAEA,OAAO,EACL,2BAA2B,EAC3B,6BAA6B,EAC7B,kCAAkC,GACnC,MAAM,eAAe,CAAC;AACvB,OAAO,EACL,0BAA0B,EAC1B,4BAA4B,EAC5B,iCAAiC,GAClC,MAAM,cAAc,CAAC;AAEtB,MAAM,UAAU,eAAe,CAAC,MAAiB,EAAE,UAA8B;IAC/E,MAAM,CAAC,cAAc,CACnB,gCAAgC,EAChC;QACE,KAAK,EAAE,gCAAgC;QACvC,WAAW,EACT,8FAA8F;YAC9F,8EAA8E;QAChF,UAAU,EAAE,iCAAiC,CAAC,KAAK;KACpD,EACD,KAAK,EAAE,IAAI,EAAE,EAAE;QACb,MAAM,MAAM,GAAG,iCAAiC,CAAC,KAAK,CAAC,IAAI,CAAC,CAAC;QAC7D,MAAM,QAAQ,GAAG,MAAM,kCAAkC,CAAC,MAAM,EAAE,UAAU,CAAC,CAAC;QAC9E,OAAO,EAAE,QAAQ,EAAE,CAAC;IACtB,CAAC,CACF,CAAC;IAEF,MAAM,CAAC,cAAc,CACnB,4BAA4B,EAC5B;QACE,KAAK,EAAE,wCAAwC;QAC/C,WAAW,EACT,uEAAuE;YACvE,qEAAqE;QACvE,UAAU,EAAE,4BAA4B,CAAC,KAAK;KAC/C,EACD,KAAK,EAAE,IAAI,EAAE,EAAE;QACb,MAAM,MAAM,GAAG,4BAA4B,CAAC,KAAK,CAAC,IAAI,CAAC,CAAC;QACxD,MAAM,QAAQ,GAAG,MAAM,6BAA6B,CAAC,MAAM,EAAE,UAAU,CAAC,CAAC;QACzE,OAAO,EAAE,QAAQ,EAAE,CAAC;IACtB,CAAC,CACF,CAAC;IAEF,MAAM,CAAC,cAAc,CACnB,wBAAwB,EACxB;QACE,KAAK,EAAE,uCAAuC;QAC9C,WAAW,EACT,yEAAyE;YACzE,mCAAmC;QACrC,UAAU,EAAE,0BAA0B,CAAC,KAAK;KAC7C,EACD,KAAK,EAAE,IAAI,EAAE,EAAE;QACb,MAAM,MAAM,GAAG,0BAA0B,CAAC,KAAK,CAAC,IAAI,CAAC,CAAC;QACtD,MAAM,QAAQ,GAAG,MAAM,2BAA2B,CAAC,MAAM,EAAE,UAAU,CAAC,CAAC;QACvE,OAAO,EAAE,QAAQ,EAAE,CAAC;IACtB,CAAC,CACF,CAAC;AACJ,CAAC"}

package/dist/prompts/schemas.d.ts

@@ -0,0 +1,22 @@
+import { z } from "zod";
+export declare const VerificarMedicamentoCompletoInput: z.ZodObject<{
+    termo: z.ZodString;
+    incluir_apresentacoes: z.ZodDefault<z.ZodBoolean>;
+    incluir_bula: z.ZodDefault<z.ZodBoolean>;
+}, z.core.$strip>;
+export type VerificarMedicamentoCompletoInputType = z.infer<typeof VerificarMedicamentoCompletoInput>;
+export declare const CompararTarjasPorClasseInput: z.ZodObject<{
+    classe_terapeutica: z.ZodString;
+    limite: z.ZodDefault<z.ZodNumber>;
+}, z.core.$strip>;
+export type CompararTarjasPorClasseInputType = z.infer<typeof CompararTarjasPorClasseInput>;
+export declare const AnalisarApresentacoesInput: z.ZodObject<{
+    nome_medicamento: z.ZodString;
+    agrupar_por: z.ZodDefault<z.ZodEnum<{
+        concentracao: "concentracao";
+        forma_farmaceutica: "forma_farmaceutica";
+        fabricante: "fabricante";
+    }>>;
+}, z.core.$strip>;
+export type AnalisarApresentacoesInputType = z.infer<typeof AnalisarApresentacoesInput>;
+//# sourceMappingURL=schemas.d.ts.map

package/dist/prompts/schemas.d.ts.map

@@ -0,0 +1 @@
+{"version":3,"file":"schemas.d.ts","sourceRoot":"","sources":["../../src/prompts/schemas.ts"],"names":[],"mappings":"AAAA,OAAO,EAAE,CAAC,EAAE,MAAM,KAAK,CAAC;AAExB,eAAO,MAAM,iCAAiC;;;;iBAI5C,CAAC;AACH,MAAM,MAAM,qCAAqC,GAAG,CAAC,CAAC,KAAK,CACzD,OAAO,iCAAiC,CACzC,CAAC;AAEF,eAAO,MAAM,4BAA4B;;;iBAGvC,CAAC;AACH,MAAM,MAAM,gCAAgC,GAAG,CAAC,CAAC,KAAK,CAAC,OAAO,4BAA4B,CAAC,CAAC;AAE5F,eAAO,MAAM,0BAA0B;;;;;;;iBAGrC,CAAC;AACH,MAAM,MAAM,8BAA8B,GAAG,CAAC,CAAC,KAAK,CAAC,OAAO,0BAA0B,CAAC,CAAC"}

package/dist/prompts/schemas.js

@@ -0,0 +1,15 @@
+import { z } from "zod";
+export const VerificarMedicamentoCompletoInput = z.object({
+    termo: z.string().min(2, "Nome comercial, princípio ativo ou parte"),
+    incluir_apresentacoes: z.boolean().default(true),
+    incluir_bula: z.boolean().default(false).describe("Se true, inclui resumo da bula (mais caro)"),
+});
+export const CompararTarjasPorClasseInput = z.object({
+    classe_terapeutica: z.string().min(3),
+    limite: z.number().int().min(1).max(100).default(50),
+});
+export const AnalisarApresentacoesInput = z.object({
+    nome_medicamento: z.string().min(2),
+    agrupar_por: z.enum(["concentracao", "forma_farmaceutica", "fabricante"]).default("concentracao"),
+});
+//# sourceMappingURL=schemas.js.map

package/dist/prompts/schemas.js.map

@@ -0,0 +1 @@
+{"version":3,"file":"schemas.js","sourceRoot":"","sources":["../../src/prompts/schemas.ts"],"names":[],"mappings":"AAAA,OAAO,EAAE,CAAC,EAAE,MAAM,KAAK,CAAC;AAExB,MAAM,CAAC,MAAM,iCAAiC,GAAG,CAAC,CAAC,MAAM,CAAC;IACxD,KAAK,EAAE,CAAC,CAAC,MAAM,EAAE,CAAC,GAAG,CAAC,CAAC,EAAE,0CAA0C,CAAC;IACpE,qBAAqB,EAAE,CAAC,CAAC,OAAO,EAAE,CAAC,OAAO,CAAC,IAAI,CAAC;IAChD,YAAY,EAAE,CAAC,CAAC,OAAO,EAAE,CAAC,OAAO,CAAC,KAAK,CAAC,CAAC,QAAQ,CAAC,4CAA4C,CAAC;CAChG,CAAC,CAAC;AAKH,MAAM,CAAC,MAAM,4BAA4B,GAAG,CAAC,CAAC,MAAM,CAAC;IACnD,kBAAkB,EAAE,CAAC,CAAC,MAAM,EAAE,CAAC,GAAG,CAAC,CAAC,CAAC;IACrC,MAAM,EAAE,CAAC,CAAC,MAAM,EAAE,CAAC,GAAG,EAAE,CAAC,GAAG,CAAC,CAAC,CAAC,CAAC,GAAG,CAAC,GAAG,CAAC,CAAC,OAAO,CAAC,EAAE,CAAC;CACrD,CAAC,CAAC;AAGH,MAAM,CAAC,MAAM,0BAA0B,GAAG,CAAC,CAAC,MAAM,CAAC;IACjD,gBAAgB,EAAE,CAAC,CAAC,MAAM,EAAE,CAAC,GAAG,CAAC,CAAC,CAAC;IACnC,WAAW,EAAE,CAAC,CAAC,IAAI,CAAC,CAAC,cAAc,EAAE,oBAAoB,EAAE,YAAY,CAAC,CAAC,CAAC,OAAO,CAAC,cAAc,CAAC;CAClG,CAAC,CAAC"}

package/dist/resources/handlers.d.ts

@@ -0,0 +1,5 @@
+import type { IBularioRepository } from "../domain/repository.js";
+export declare const TARJAS_JSON: string;
+export declare function getClassesTerapeuticasJson(_repository: IBularioRepository): Promise<string>;
+export declare const SCOPE_MARKDOWN = "# Escopo do MCP @mcpassure/mcp-anvisa-bulario\n\n## \uD83C\uDDE7\uD83C\uDDF7 Portugu\u00EAs (BR)\n\n### O que este MCP faz\n\nConsulta ao **Bul\u00E1rio Eletr\u00F4nico da ANVISA** (Ag\u00EAncia Nacional de Vigil\u00E2ncia Sanit\u00E1ria), incluindo:\n\n- Busca de medicamentos por nome comercial, princ\u00EDpio ativo, classe terap\u00EAutica ou tarja\n- Recupera\u00E7\u00E3o de bulas (paciente e profissional) em PDF via n\u00FAmero de registro ANVISA\n- Listagem de apresenta\u00E7\u00F5es comerciais (concentra\u00E7\u00E3o, forma farmac\u00EAutica, fabricante)\n- Filtragem por tarja regulat\u00F3ria (Livre, Vermelha, Preta)\n- Transport Playwright resistente a prote\u00E7\u00E3o Cloudflare do portal ANVISA\n- Cache local SQLite para redu\u00E7\u00E3o de lat\u00EAncia e requisi\u00E7\u00F5es repetidas\n\n### O que este MCP N\u00C3O faz\n\n- \u274C N\u00E3o substitui consulta direta \u00E0 ANVISA para fins regulat\u00F3rios oficiais\n- \u274C N\u00E3o fornece pre\u00E7os de medicamentos (consulte CMED/ANVISA)\n- \u274C N\u00E3o verifica intera\u00E7\u00F5es medicamentosas\n- \u274C N\u00E3o emite receitas ou laudos m\u00E9dicos\n- \u274C N\u00E3o cobre medicamentos fitoter\u00E1picos, cosm\u00E9ticos ou saneantes\n- \u274C N\u00E3o acessa dados de farmacovigil\u00E2ncia ou notifica\u00E7\u00F5es de eventos adversos\n\n### \u26A0\uFE0F Disclaimer regulat\u00F3rio\n\nDados obtidos do Bul\u00E1rio Eletr\u00F4nico ANVISA com lat\u00EAncia de cache configur\u00E1vel.\n**Decis\u00F5es cl\u00EDnicas ou regulat\u00F3rias devem sempre utilizar a fonte ANVISA oficial e atualizada.**\n\nMedicamentos sob **Tarja Preta** (Portaria SVS/MS 344/1998) est\u00E3o sujeitos a controle especial \u2014\npsicotr\u00F3picos, entorpecentes, precursores e outras subst\u00E2ncias de controle especial.\nO uso inadequado \u00E9 crime previsto em lei.\n\n---\n\n## \uD83C\uDDFA\uD83C\uDDF8 English\n\n### What this MCP does\n\nQueries the **ANVISA Electronic Drug Information Database** (Brazilian Health Regulatory Agency), including:\n\n- Search medications by trade name, active ingredient (INN/DCB), therapeutic class, or controlled-substance tier\n- Retrieve patient and prescriber leaflets (bulas) in PDF via ANVISA registration number\n- List commercial presentations (dosage, pharmaceutical form, manufacturer)\n- Filter by regulatory tier (Sem Tarja/OTC, Tarja Vermelha/Rx, Tarja Preta/controlled)\n- Cloudflare-resistant Playwright transport for the ANVISA portal\n- Local SQLite cache to reduce latency on repeated queries\n\n### What this MCP does NOT do\n\n- \u274C Does not replace official ANVISA consultation for regulatory compliance\n- \u274C Does not provide drug pricing (see CMED/ANVISA)\n- \u274C Does not check drug interactions\n- \u274C Does not issue prescriptions or medical reports\n- \u274C Does not cover phytotherapeutics, cosmetics, or sanitizers\n- \u274C Does not access pharmacovigilance data or adverse event reports\n\n### \u26A0\uFE0F Regulatory disclaimer\n\nData sourced from the ANVISA Electronic Drug Information Database with configurable cache latency.\n**Clinical or regulatory decisions must always use the official and up-to-date ANVISA source.**\n\nMedications classified as **Tarja Preta** (Black-banded \u2014 controlled substance under Brazilian\nOrdinance SVS/MS 344/1998) are subject to special control \u2014 psychotropics, narcotics, precursors,\nand other controlled substances. Misuse is a criminal offense under Brazilian law.\n";
+//# sourceMappingURL=handlers.d.ts.map

package/dist/resources/handlers.d.ts.map

@@ -0,0 +1 @@
+{"version":3,"file":"handlers.d.ts","sourceRoot":"","sources":["../../src/resources/handlers.ts"],"names":[],"mappings":"AAAA,OAAO,KAAK,EAAE,kBAAkB,EAAE,MAAM,yBAAyB,CAAC;AAElE,eAAO,MAAM,WAAW,QA4BvB,CAAC;AAgDF,wBAAsB,0BAA0B,CAAC,WAAW,EAAE,kBAAkB,GAAG,OAAO,CAAC,MAAM,CAAC,CAWjG;AAED,eAAO,MAAM,cAAc,m6GAiE1B,CAAC"}

package/dist/resources/handlers.js

@@ -0,0 +1,145 @@
+export const TARJAS_JSON = JSON.stringify({
+    tarjas: [
+        {
+            codigo: "sem_tarja",
+            nome: "Sem tarja",
+            descricao: "Venda livre — sem retenção de receita.",
+        },
+        {
+            codigo: "amarela",
+            nome: "Tarja Amarela",
+            descricao: "Venda sob prescrição — antibióticos e outros medicamentos sujeitos a controle.",
+        },
+        {
+            codigo: "vermelha",
+            nome: "Tarja Vermelha",
+            descricao: "Venda sob prescrição médica — receita simples retida.",
+        },
+        {
+            codigo: "preta",
+            nome: "Tarja Preta",
+            descricao: "Controle especial — Portaria 344/98 (psicotrópicos, entorpecentes).",
+        },
+    ],
+    fonte: "RDC ANVISA 357/2020 e Portaria SVS/MS 344/1998",
+}, null, 2);
+const CLASSES_TERAPEUTICAS_HARDCODED = [
+    "Analgésico",
+    "Anti-inflamatório",
+    "Antibiótico",
+    "Antifúngico",
+    "Antiviral",
+    "Antiparasitário",
+    "Anti-hipertensivo",
+    "Antidiabético",
+    "Anticoagulante",
+    "Antiarrítmico",
+    "Diurético",
+    "Broncodilatador",
+    "Corticosteroide",
+    "Imunossupressor",
+    "Antineoplásico",
+    "Ansiolítico",
+    "Antidepressivo",
+    "Antipsicótico",
+    "Antiepiléptico",
+    "Antiparkinsônico",
+    "Opiáceo",
+    "Psicotrópico",
+    "Hormônio",
+    "Anticoncepcional",
+    "Vitamina e Suplemento",
+    "Gastroprotetores",
+    "Antiácido",
+    "Antiemético",
+    "Laxante",
+    "Antidiarreico",
+    "Hipnótico",
+    "Relaxante Muscular",
+    "Imunomodulador",
+    "Vacina",
+    "Hemostático",
+    "Antialérgico",
+    "Descongestionante",
+    "Mucolítico",
+    "Antitussígeno",
+    "Dermatológico",
+    "Oftálmico",
+    "Otológico",
+    "Antisséptico",
+];
+export async function getClassesTerapeuticasJson(_repository) {
+    return JSON.stringify({
+        classes_terapeuticas: CLASSES_TERAPEUTICAS_HARDCODED.sort(),
+        total: CLASSES_TERAPEUTICAS_HARDCODED.length,
+        fonte: "Bulário Eletrônico ANVISA — principais classes indexadas",
+        nota: "Lista representativa. Consulte o Bulário ANVISA para listagem completa atualizada.",
+    }, null, 2);
+}
+export const SCOPE_MARKDOWN = `# Escopo do MCP @mcpassure/mcp-anvisa-bulario
+
+## 🇧🇷 Português (BR)
+
+### O que este MCP faz
+
+Consulta ao **Bulário Eletrônico da ANVISA** (Agência Nacional de Vigilância Sanitária), incluindo:
+
+- Busca de medicamentos por nome comercial, princípio ativo, classe terapêutica ou tarja
+- Recuperação de bulas (paciente e profissional) em PDF via número de registro ANVISA
+- Listagem de apresentações comerciais (concentração, forma farmacêutica, fabricante)
+- Filtragem por tarja regulatória (Livre, Vermelha, Preta)
+- Transport Playwright resistente a proteção Cloudflare do portal ANVISA
+- Cache local SQLite para redução de latência e requisições repetidas
+
+### O que este MCP NÃO faz
+
+- ❌ Não substitui consulta direta à ANVISA para fins regulatórios oficiais
+- ❌ Não fornece preços de medicamentos (consulte CMED/ANVISA)
+- ❌ Não verifica interações medicamentosas
+- ❌ Não emite receitas ou laudos médicos
+- ❌ Não cobre medicamentos fitoterápicos, cosméticos ou saneantes
+- ❌ Não acessa dados de farmacovigilância ou notificações de eventos adversos
+
+### ⚠️ Disclaimer regulatório
+
+Dados obtidos do Bulário Eletrônico ANVISA com latência de cache configurável.
+**Decisões clínicas ou regulatórias devem sempre utilizar a fonte ANVISA oficial e atualizada.**
+
+Medicamentos sob **Tarja Preta** (Portaria SVS/MS 344/1998) estão sujeitos a controle especial —
+psicotrópicos, entorpecentes, precursores e outras substâncias de controle especial.
+O uso inadequado é crime previsto em lei.
+
+---
+
+## 🇺🇸 English
+
+### What this MCP does
+
+Queries the **ANVISA Electronic Drug Information Database** (Brazilian Health Regulatory Agency), including:
+
+- Search medications by trade name, active ingredient (INN/DCB), therapeutic class, or controlled-substance tier
+- Retrieve patient and prescriber leaflets (bulas) in PDF via ANVISA registration number
+- List commercial presentations (dosage, pharmaceutical form, manufacturer)
+- Filter by regulatory tier (Sem Tarja/OTC, Tarja Vermelha/Rx, Tarja Preta/controlled)
+- Cloudflare-resistant Playwright transport for the ANVISA portal
+- Local SQLite cache to reduce latency on repeated queries
+
+### What this MCP does NOT do
+
+- ❌ Does not replace official ANVISA consultation for regulatory compliance
+- ❌ Does not provide drug pricing (see CMED/ANVISA)
+- ❌ Does not check drug interactions
+- ❌ Does not issue prescriptions or medical reports
+- ❌ Does not cover phytotherapeutics, cosmetics, or sanitizers
+- ❌ Does not access pharmacovigilance data or adverse event reports
+
+### ⚠️ Regulatory disclaimer
+
+Data sourced from the ANVISA Electronic Drug Information Database with configurable cache latency.
+**Clinical or regulatory decisions must always use the official and up-to-date ANVISA source.**
+
+Medications classified as **Tarja Preta** (Black-banded — controlled substance under Brazilian
+Ordinance SVS/MS 344/1998) are subject to special control — psychotropics, narcotics, precursors,
+and other controlled substances. Misuse is a criminal offense under Brazilian law.
+`;
+//# sourceMappingURL=handlers.js.map

package/dist/resources/handlers.js.map

@@ -0,0 +1 @@
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package/dist/resources/index.d.ts

@@ -0,0 +1,4 @@
+import type { McpServer } from "@modelcontextprotocol/sdk/server/mcp.js";
+import type { IBularioRepository } from "../domain/repository.js";
+export declare function registerResources(server: McpServer, repository: IBularioRepository): void;
+//# sourceMappingURL=index.d.ts.map

package/dist/resources/index.d.ts.map

@@ -0,0 +1 @@
+{"version":3,"file":"index.d.ts","sourceRoot":"","sources":["../../src/resources/index.ts"],"names":[],"mappings":"AAAA,OAAO,KAAK,EAAE,SAAS,EAAE,MAAM,yCAAyC,CAAC;AACzE,OAAO,KAAK,EAAE,kBAAkB,EAAE,MAAM,yBAAyB,CAAC;AAGlE,wBAAgB,iBAAiB,CAAC,MAAM,EAAE,SAAS,EAAE,UAAU,EAAE,kBAAkB,GAAG,IAAI,CAiEzF"}

package/dist/resources/index.js

@@ -0,0 +1,48 @@
+import { getClassesTerapeuticasJson, SCOPE_MARKDOWN, TARJAS_JSON } from "./handlers.js";
+export function registerResources(server, repository) {
+    server.registerResource("bulario://tarjas", "bulario://tarjas", {
+        title: "Taxonomia de Tarjas ANVISA",
+        description: "Taxonomia regulatória de tarjas (RDC 357/2020, Portaria 344/98). " +
+            "Lista todas as categorias de controle de venda de medicamentos no Brasil.",
+        mimeType: "application/json",
+    }, async () => ({
+        contents: [
+            {
+                uri: "bulario://tarjas",
+                mimeType: "application/json",
+                text: TARJAS_JSON,
+            },
+        ],
+    }));
+    server.registerResource("bulario://classes_terapeuticas", "bulario://classes_terapeuticas", {
+        title: "Classes Terapêuticas Indexadas",
+        description: "Lista das principais classes terapêuticas indexadas no Bulário Eletrônico ANVISA.",
+        mimeType: "application/json",
+    }, async () => {
+        const json = await getClassesTerapeuticasJson(repository);
+        return {
+            contents: [
+                {
+                    uri: "bulario://classes_terapeuticas",
+                    mimeType: "application/json",
+                    text: json,
+                },
+            ],
+        };
+    });
+    server.registerResource("bulario://scope", "bulario://scope", {
+        title: "Escopo do MCP (PT/EN)",
+        description: "Escopo do MCP (PT/EN): o que faz, o que não faz, disclaimer regulatório " +
+            "e atenção especial a Tarja Preta (Portaria 344/98).",
+        mimeType: "text/markdown",
+    }, async () => ({
+        contents: [
+            {
+                uri: "bulario://scope",
+                mimeType: "text/markdown",
+                text: SCOPE_MARKDOWN,
+            },
+        ],
+    }));
+}
+//# sourceMappingURL=index.js.map

package/dist/resources/index.js.map

@@ -0,0 +1 @@
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