@jbrowse/plugin-wiggle 1.5.9 → 1.6.4

package/dist/BigWigAdapter/BigWigAdapter.d.ts

@@ -1,9 +1,8 @@
 import { BaseFeatureDataAdapter, BaseOptions } from '@jbrowse/core/data_adapters/BaseAdapter';
 import { AugmentedRegion as Region } from '@jbrowse/core/util/types';
 import { Feature } from '@jbrowse/core/util/simpleFeature';
-import { Instance } from 'mobx-state-tree';
+import { AnyConfigurationModel } from '@jbrowse/core/configuration/configurationSchema';
 import PluginManager from '@jbrowse/core/PluginManager';
-import configSchema from './configSchema';
 import { getSubAdapterType } from '@jbrowse/core/data_adapters/dataAdapterCache';
 interface WiggleOptions extends BaseOptions {
     resolution?: number;
@@ -11,12 +10,15 @@ interface WiggleOptions extends BaseOptions {
 export default class BigWigAdapter extends BaseFeatureDataAdapter {
     private bigwig;
     static capabilities: string[];
-    constructor(config: Instance<typeof configSchema>, getSubAdapter?: getSubAdapterType, pluginManager?: PluginManager);
+    constructor(config: AnyConfigurationModel, getSubAdapter?: getSubAdapterType, pluginManager?: PluginManager);
     private setup;
     getRefNames(opts?: BaseOptions): Promise<string[]>;
     refIdToName(refId: number): Promise<any>;
     getGlobalStats(opts?: BaseOptions): Promise<import("@jbrowse/core/util/stats").FeatureStats>;
     getFeatures(region: Region, opts?: WiggleOptions): import("rxjs").Observable<Feature>;
+    estimateRegionsStats(_regions: Region[]): Promise<{
+        featureDensity: number;
+    }>;
     freeResources(): void;
 }
 export {};

package/dist/LinearWiggleDisplay/components/SetColorDialog.d.ts

@@ -1,8 +1,10 @@
 /// <reference types="react" />
-export default function SetColorDialog(props: {
+export default function SetColorDialog({ model, handleClose, }: {
     model: {
         color: number;
-        setColor: Function;
+        setColor: (arg?: string) => void;
+        setPosColor: (arg?: string) => void;
+        setNegColor: (arg?: string) => void;
     };
     handleClose: () => void;
 }): JSX.Element;

package/dist/LinearWiggleDisplay/models/model.d.ts

@@ -57,6 +57,7 @@ declare const stateModelFactory: (pluginManager: PluginManager, configSchema: An
         beforeDestroy(): void;
     }, import("mobx-state-tree")._NotCustomized, import("mobx-state-tree")._NotCustomized>>;
     userBpPerPxLimit: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<number>>;
+    userByteSizeLimit: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<number>>;
 } & {
     type: import("mobx-state-tree").ISimpleType<"LinearWiggleDisplay">;
     configuration: import("mobx-state-tree").ITypeUnion<any, any, any>;
@@ -64,6 +65,8 @@ declare const stateModelFactory: (pluginManager: PluginManager, configSchema: An
     resolution: import("mobx-state-tree").IOptionalIType<import("mobx-state-tree").ISimpleType<number>, [undefined]>;
     fill: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<boolean>>;
     color: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
+    posColor: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
+    negColor: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
     summaryScoreMode: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
     rendererTypeNameState: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
     scale: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
@@ -126,15 +129,17 @@ declare const stateModelFactory: (pluginManager: PluginManager, configSchema: An
     setRpcDriverName(rpcDriverName: string): void;
     reload(): void;
 } & {
+    currBpPerPx: number;
     message: string;
     featureIdUnderMouse: string | undefined;
     contextMenuFeature: Feature | undefined;
     scrollTop: number;
+    estimatedRegionStatsP: Promise<import("@jbrowse/core/data_adapters/BaseAdapter").Stats> | undefined;
+    estimatedRegionStats: import("@jbrowse/core/data_adapters/BaseAdapter").Stats | undefined;
 } & {
     readonly blockType: "staticBlocks" | "dynamicBlocks";
     readonly blockDefinitions: import("@jbrowse/core/util/blockTypes").BlockSet;
 } & {
-    readonly maxViewBpPerPx: any;
     readonly renderDelay: number;
     readonly TooltipComponent: React.FC<any>;
     readonly selectedFeatureId: string | undefined;
@@ -145,14 +150,28 @@ declare const stateModelFactory: (pluginManager: PluginManager, configSchema: An
     getFeatureOverlapping(blockKey: string, x: number, y: number): any;
     getFeatureByID(blockKey: string, id: string): [number, number, number, number] | undefined;
     searchFeatureByID(id: string): [number, number, number, number] | undefined;
+    readonly currentBytesRequested: number;
+    readonly currentFeatureScreenDensity: number;
+    readonly maxFeatureScreenDensity: any;
+    readonly estimatedStatsReady: boolean;
+    readonly maxAllowableBytes: number;
 } & {
+    setMessage(message: string): void;
     afterAttach(): void;
+    estimateRegionsStats(regions: import("@jbrowse/core/util").Region[], opts: {
+        headers?: Record<string, string> | undefined;
+        signal?: AbortSignal | undefined;
+        filters?: string[] | undefined;
+    }): Promise<import("@jbrowse/core/data_adapters/BaseAdapter").Stats>;
+    setRegionStatsP(p?: Promise<import("@jbrowse/core/data_adapters/BaseAdapter").Stats> | undefined): void;
+    setRegionStats(estimatedRegionStats?: import("@jbrowse/core/data_adapters/BaseAdapter").Stats | undefined): void;
+    clearRegionStats(): void;
     setHeight(displayHeight: number): number;
     resizeHeight(distance: number): number;
     setScrollTop(scrollTop: number): void;
-    setUserBpPerPxLimit(limit: number): void;
-    setMessage(message: string): void;
+    updateStatsLimit(stats: import("@jbrowse/core/data_adapters/BaseAdapter").Stats): void;
     addBlock(key: string, block: import("@jbrowse/core/util/blockTypes").BaseBlock): void;
+    setCurrBpPerPx(n: number): void;
     deleteBlock(key: string): void;
     selectFeature(feature: Feature): void;
     clearFeatureSelection(): void;
@@ -160,7 +179,13 @@ declare const stateModelFactory: (pluginManager: PluginManager, configSchema: An
     reload(): void;
     setContextMenuFeature(feature?: Feature | undefined): void;
 } & {
-    regionCannotBeRenderedText(_region: import("@jbrowse/core/util").Region): "" | "Zoom in to see features";
+    readonly regionTooLarge: boolean;
+    readonly regionTooLargeReason: string;
+} & {
+    reload(): Promise<void>;
+    afterAttach(): void;
+} & {
+    regionCannotBeRenderedText(_region: import("@jbrowse/core/util").Region): "" | "Force load to see features";
     regionCannotBeRendered(_region: import("@jbrowse/core/util").Region): JSX.Element | undefined;
     trackMenuItems(): import("@jbrowse/core/ui").MenuItem[];
     contextMenuItems(): {
@@ -174,7 +199,7 @@ declare const stateModelFactory: (pluginManager: PluginManager, configSchema: An
         overrideHeight: number;
     }): Promise<JSX.Element>;
 } & {
-    ready: boolean;
+    statsReady: boolean;
     message: string | undefined;
     stats: {
         scoreMin: number;
@@ -187,6 +212,8 @@ declare const stateModelFactory: (pluginManager: PluginManager, configSchema: An
         scoreMax: number;
     }): void;
     setColor(color: string): void;
+    setPosColor(color: string): void;
+    setNegColor(color: string): void;
     setLoading(aborter: AbortController): void;
     selectFeature(feature: Feature): void;
     setResolution(res: number): void;
@@ -206,11 +233,12 @@ declare const stateModelFactory: (pluginManager: PluginManager, configSchema: An
     readonly rendererTypeName: string;
     readonly filters: undefined;
     readonly scaleType: any;
-    readonly filled: any;
     readonly maxScore: any;
     readonly minScore: any;
+} & {
     readonly rendererConfig: any;
 } & {
+    readonly filled: any;
     readonly summaryScoreModeSetting: any;
     readonly domain: number[];
     readonly needsScalebar: boolean;
@@ -253,6 +281,7 @@ declare const stateModelFactory: (pluginManager: PluginManager, configSchema: An
     rpcDriverName: string | undefined;
     height: number;
     userBpPerPxLimit: number | undefined;
+    userByteSizeLimit: number | undefined;
 } & import("mobx-state-tree")._NotCustomized>;
 export declare type WiggleDisplayStateModel = ReturnType<typeof stateModelFactory>;
 export declare type WiggleDisplayModel = Instance<WiggleDisplayStateModel>;

package/dist/index.d.ts

@@ -64,6 +64,7 @@ export default class WigglePlugin extends Plugin {
                     beforeDestroy(): void;
                 }, import("mobx-state-tree")._NotCustomized, import("mobx-state-tree")._NotCustomized>>;
                 userBpPerPxLimit: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<number>>;
+                userByteSizeLimit: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<number>>;
             } & {
                 type: import("mobx-state-tree").ISimpleType<"LinearWiggleDisplay">;
                 configuration: import("mobx-state-tree").ITypeUnion<any, any, any>;
@@ -71,6 +72,8 @@ export default class WigglePlugin extends Plugin {
                 resolution: import("mobx-state-tree").IOptionalIType<import("mobx-state-tree").ISimpleType<number>, [undefined]>;
                 fill: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<boolean>>;
                 color: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
+                posColor: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
+                negColor: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
                 summaryScoreMode: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
                 rendererTypeNameState: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
                 scale: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
@@ -133,15 +136,17 @@ export default class WigglePlugin extends Plugin {
                 setRpcDriverName(rpcDriverName: string): void;
                 reload(): void;
             } & {
+                currBpPerPx: number;
                 message: string;
                 featureIdUnderMouse: string | undefined;
                 contextMenuFeature: import("@jbrowse/core/util/simpleFeature").Feature | undefined;
                 scrollTop: number;
+                estimatedRegionStatsP: Promise<import("@jbrowse/core/data_adapters/BaseAdapter").Stats> | undefined;
+                estimatedRegionStats: import("@jbrowse/core/data_adapters/BaseAdapter").Stats | undefined;
             } & {
                 readonly blockType: "staticBlocks" | "dynamicBlocks";
                 readonly blockDefinitions: import("@jbrowse/core/util/blockTypes").BlockSet;
             } & {
-                readonly maxViewBpPerPx: any;
                 readonly renderDelay: number;
                 readonly TooltipComponent: import("react").FC<any>;
                 readonly selectedFeatureId: string | undefined;
@@ -152,14 +157,28 @@ export default class WigglePlugin extends Plugin {
                 getFeatureOverlapping(blockKey: string, x: number, y: number): any;
                 getFeatureByID(blockKey: string, id: string): [number, number, number, number] | undefined;
                 searchFeatureByID(id: string): [number, number, number, number] | undefined;
+                readonly currentBytesRequested: number;
+                readonly currentFeatureScreenDensity: number;
+                readonly maxFeatureScreenDensity: any;
+                readonly estimatedStatsReady: boolean;
+                readonly maxAllowableBytes: number;
             } & {
+                setMessage(message: string): void;
                 afterAttach(): void;
+                estimateRegionsStats(regions: import("@jbrowse/core/util/types").Region[], opts: {
+                    headers?: Record<string, string> | undefined;
+                    signal?: AbortSignal | undefined;
+                    filters?: string[] | undefined;
+                }): Promise<import("@jbrowse/core/data_adapters/BaseAdapter").Stats>;
+                setRegionStatsP(p?: Promise<import("@jbrowse/core/data_adapters/BaseAdapter").Stats> | undefined): void;
+                setRegionStats(estimatedRegionStats?: import("@jbrowse/core/data_adapters/BaseAdapter").Stats | undefined): void;
+                clearRegionStats(): void;
                 setHeight(displayHeight: number): number;
                 resizeHeight(distance: number): number;
                 setScrollTop(scrollTop: number): void;
-                setUserBpPerPxLimit(limit: number): void;
-                setMessage(message: string): void;
+                updateStatsLimit(stats: import("@jbrowse/core/data_adapters/BaseAdapter").Stats): void;
                 addBlock(key: string, block: import("@jbrowse/core/util/blockTypes").BaseBlock): void;
+                setCurrBpPerPx(n: number): void;
                 deleteBlock(key: string): void;
                 selectFeature(feature: import("@jbrowse/core/util/simpleFeature").Feature): void;
                 clearFeatureSelection(): void;
@@ -167,7 +186,13 @@ export default class WigglePlugin extends Plugin {
                 reload(): void;
                 setContextMenuFeature(feature?: import("@jbrowse/core/util/simpleFeature").Feature | undefined): void;
             } & {
-                regionCannotBeRenderedText(_region: import("@jbrowse/core/util/types").Region): "" | "Zoom in to see features";
+                readonly regionTooLarge: boolean;
+                readonly regionTooLargeReason: string;
+            } & {
+                reload(): Promise<void>;
+                afterAttach(): void;
+            } & {
+                regionCannotBeRenderedText(_region: import("@jbrowse/core/util/types").Region): "" | "Force load to see features";
                 regionCannotBeRendered(_region: import("@jbrowse/core/util/types").Region): JSX.Element | undefined;
                 trackMenuItems(): import("@jbrowse/core/ui").MenuItem[];
                 contextMenuItems(): {
@@ -181,7 +206,7 @@ export default class WigglePlugin extends Plugin {
                     overrideHeight: number;
                 }): Promise<JSX.Element>;
             } & {
-                ready: boolean;
+                statsReady: boolean;
                 message: string | undefined;
                 stats: {
                     scoreMin: number;
@@ -194,6 +219,8 @@ export default class WigglePlugin extends Plugin {
                     scoreMax: number;
                 }): void;
                 setColor(color: string): void;
+                setPosColor(color: string): void;
+                setNegColor(color: string): void;
                 setLoading(aborter: AbortController): void;
                 selectFeature(feature: import("@jbrowse/core/util/simpleFeature").Feature): void;
                 setResolution(res: number): void;
@@ -213,11 +240,12 @@ export default class WigglePlugin extends Plugin {
                 readonly rendererTypeName: string;
                 readonly filters: undefined;
                 readonly scaleType: any;
-                readonly filled: any;
                 readonly maxScore: any;
                 readonly minScore: any;
+            } & {
                 readonly rendererConfig: any;
             } & {
+                readonly filled: any;
                 readonly summaryScoreModeSetting: any;
                 readonly domain: number[];
                 readonly needsScalebar: boolean;
@@ -307,6 +335,7 @@ export default class WigglePlugin extends Plugin {
                     beforeDestroy(): void;
                 }, import("mobx-state-tree")._NotCustomized, import("mobx-state-tree")._NotCustomized>>;
                 userBpPerPxLimit: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<number>>;
+                userByteSizeLimit: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<number>>;
             } & {
                 type: import("mobx-state-tree").ISimpleType<"LinearWiggleDisplay">;
                 configuration: import("mobx-state-tree").ITypeUnion<any, any, any>;
@@ -314,6 +343,8 @@ export default class WigglePlugin extends Plugin {
                 resolution: import("mobx-state-tree").IOptionalIType<import("mobx-state-tree").ISimpleType<number>, [undefined]>;
                 fill: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<boolean>>;
                 color: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
+                posColor: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
+                negColor: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
                 summaryScoreMode: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
                 rendererTypeNameState: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
                 scale: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
@@ -376,15 +407,17 @@ export default class WigglePlugin extends Plugin {
                 setRpcDriverName(rpcDriverName: string): void;
                 reload(): void;
             } & {
+                currBpPerPx: number;
                 message: string;
                 featureIdUnderMouse: string | undefined;
                 contextMenuFeature: import("@jbrowse/core/util/simpleFeature").Feature | undefined;
                 scrollTop: number;
+                estimatedRegionStatsP: Promise<import("@jbrowse/core/data_adapters/BaseAdapter").Stats> | undefined;
+                estimatedRegionStats: import("@jbrowse/core/data_adapters/BaseAdapter").Stats | undefined;
             } & {
                 readonly blockType: "staticBlocks" | "dynamicBlocks";
                 readonly blockDefinitions: import("@jbrowse/core/util/blockTypes").BlockSet;
             } & {
-                readonly maxViewBpPerPx: any;
                 readonly renderDelay: number;
                 readonly TooltipComponent: import("react").FC<any>;
                 readonly selectedFeatureId: string | undefined;
@@ -395,14 +428,28 @@ export default class WigglePlugin extends Plugin {
                 getFeatureOverlapping(blockKey: string, x: number, y: number): any;
                 getFeatureByID(blockKey: string, id: string): [number, number, number, number] | undefined;
                 searchFeatureByID(id: string): [number, number, number, number] | undefined;
+                readonly currentBytesRequested: number;
+                readonly currentFeatureScreenDensity: number;
+                readonly maxFeatureScreenDensity: any;
+                readonly estimatedStatsReady: boolean;
+                readonly maxAllowableBytes: number;
             } & {
+                setMessage(message: string): void;
                 afterAttach(): void;
+                estimateRegionsStats(regions: import("@jbrowse/core/util/types").Region[], opts: {
+                    headers?: Record<string, string> | undefined;
+                    signal?: AbortSignal | undefined;
+                    filters?: string[] | undefined;
+                }): Promise<import("@jbrowse/core/data_adapters/BaseAdapter").Stats>;
+                setRegionStatsP(p?: Promise<import("@jbrowse/core/data_adapters/BaseAdapter").Stats> | undefined): void;
+                setRegionStats(estimatedRegionStats?: import("@jbrowse/core/data_adapters/BaseAdapter").Stats | undefined): void;
+                clearRegionStats(): void;
                 setHeight(displayHeight: number): number;
                 resizeHeight(distance: number): number;
                 setScrollTop(scrollTop: number): void;
-                setUserBpPerPxLimit(limit: number): void;
-                setMessage(message: string): void;
+                updateStatsLimit(stats: import("@jbrowse/core/data_adapters/BaseAdapter").Stats): void;
                 addBlock(key: string, block: import("@jbrowse/core/util/blockTypes").BaseBlock): void;
+                setCurrBpPerPx(n: number): void;
                 deleteBlock(key: string): void;
                 selectFeature(feature: import("@jbrowse/core/util/simpleFeature").Feature): void;
                 clearFeatureSelection(): void;
@@ -410,7 +457,13 @@ export default class WigglePlugin extends Plugin {
                 reload(): void;
                 setContextMenuFeature(feature?: import("@jbrowse/core/util/simpleFeature").Feature | undefined): void;
             } & {
-                regionCannotBeRenderedText(_region: import("@jbrowse/core/util/types").Region): "" | "Zoom in to see features";
+                readonly regionTooLarge: boolean;
+                readonly regionTooLargeReason: string;
+            } & {
+                reload(): Promise<void>;
+                afterAttach(): void;
+            } & {
+                regionCannotBeRenderedText(_region: import("@jbrowse/core/util/types").Region): "" | "Force load to see features";
                 regionCannotBeRendered(_region: import("@jbrowse/core/util/types").Region): JSX.Element | undefined;
                 trackMenuItems(): import("@jbrowse/core/ui").MenuItem[];
                 contextMenuItems(): {
@@ -424,7 +477,7 @@ export default class WigglePlugin extends Plugin {
                     overrideHeight: number;
                 }): Promise<JSX.Element>;
             } & {
-                ready: boolean;
+                statsReady: boolean;
                 message: string | undefined;
                 stats: {
                     scoreMin: number;
@@ -437,6 +490,8 @@ export default class WigglePlugin extends Plugin {
                     scoreMax: number;
                 }): void;
                 setColor(color: string): void;
+                setPosColor(color: string): void;
+                setNegColor(color: string): void;
                 setLoading(aborter: AbortController): void;
                 selectFeature(feature: import("@jbrowse/core/util/simpleFeature").Feature): void;
                 setResolution(res: number): void;
@@ -456,11 +511,12 @@ export default class WigglePlugin extends Plugin {
                 readonly rendererTypeName: string;
                 readonly filters: undefined;
                 readonly scaleType: any;
-                readonly filled: any;
                 readonly maxScore: any;
                 readonly minScore: any;
+            } & {
                 readonly rendererConfig: any;
             } & {
+                readonly filled: any;
                 readonly summaryScoreModeSetting: any;
                 readonly domain: number[];
                 readonly needsScalebar: boolean;
@@ -503,6 +559,7 @@ export default class WigglePlugin extends Plugin {
                 rpcDriverName: string | undefined;
                 height: number;
                 userBpPerPxLimit: number | undefined;
+                userByteSizeLimit: number | undefined;
             } & import("mobx-state-tree")._NotCustomized>>;
         }) => JSX.Element;
         XYPlotRendererReactComponent: (props: {
@@ -573,6 +630,7 @@ export default class WigglePlugin extends Plugin {
                 beforeDestroy(): void;
             }, import("mobx-state-tree")._NotCustomized, import("mobx-state-tree")._NotCustomized>>;
             userBpPerPxLimit: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<number>>;
+            userByteSizeLimit: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<number>>;
         } & {
             type: import("mobx-state-tree").ISimpleType<"LinearWiggleDisplay">;
             configuration: import("mobx-state-tree").ITypeUnion<any, any, any>;
@@ -580,6 +638,8 @@ export default class WigglePlugin extends Plugin {
             resolution: import("mobx-state-tree").IOptionalIType<import("mobx-state-tree").ISimpleType<number>, [undefined]>;
             fill: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<boolean>>;
             color: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
+            posColor: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
+            negColor: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
             summaryScoreMode: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
             rendererTypeNameState: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
             scale: import("mobx-state-tree").IMaybe<import("mobx-state-tree").ISimpleType<string>>;
@@ -642,15 +702,17 @@ export default class WigglePlugin extends Plugin {
             setRpcDriverName(rpcDriverName: string): void;
             reload(): void;
         } & {
+            currBpPerPx: number;
             message: string;
             featureIdUnderMouse: string | undefined;
             contextMenuFeature: import("@jbrowse/core/util/simpleFeature").Feature | undefined;
             scrollTop: number;
+            estimatedRegionStatsP: Promise<import("@jbrowse/core/data_adapters/BaseAdapter").Stats> | undefined;
+            estimatedRegionStats: import("@jbrowse/core/data_adapters/BaseAdapter").Stats | undefined;
         } & {
             readonly blockType: "staticBlocks" | "dynamicBlocks";
             readonly blockDefinitions: import("@jbrowse/core/util/blockTypes").BlockSet;
         } & {
-            readonly maxViewBpPerPx: any;
             readonly renderDelay: number;
             readonly TooltipComponent: import("react").FC<any>;
             readonly selectedFeatureId: string | undefined;
@@ -661,14 +723,28 @@ export default class WigglePlugin extends Plugin {
             getFeatureOverlapping(blockKey: string, x: number, y: number): any;
             getFeatureByID(blockKey: string, id: string): [number, number, number, number] | undefined;
             searchFeatureByID(id: string): [number, number, number, number] | undefined;
+            readonly currentBytesRequested: number;
+            readonly currentFeatureScreenDensity: number;
+            readonly maxFeatureScreenDensity: any;
+            readonly estimatedStatsReady: boolean;
+            readonly maxAllowableBytes: number;
         } & {
+            setMessage(message: string): void;
             afterAttach(): void;
+            estimateRegionsStats(regions: import("@jbrowse/core/util/types").Region[], opts: {
+                headers?: Record<string, string> | undefined;
+                signal?: AbortSignal | undefined;
+                filters?: string[] | undefined;
+            }): Promise<import("@jbrowse/core/data_adapters/BaseAdapter").Stats>;
+            setRegionStatsP(p?: Promise<import("@jbrowse/core/data_adapters/BaseAdapter").Stats> | undefined): void;
+            setRegionStats(estimatedRegionStats?: import("@jbrowse/core/data_adapters/BaseAdapter").Stats | undefined): void;
+            clearRegionStats(): void;
             setHeight(displayHeight: number): number;
             resizeHeight(distance: number): number;
             setScrollTop(scrollTop: number): void;
-            setUserBpPerPxLimit(limit: number): void;
-            setMessage(message: string): void;
+            updateStatsLimit(stats: import("@jbrowse/core/data_adapters/BaseAdapter").Stats): void;
             addBlock(key: string, block: import("@jbrowse/core/util/blockTypes").BaseBlock): void;
+            setCurrBpPerPx(n: number): void;
             deleteBlock(key: string): void;
             selectFeature(feature: import("@jbrowse/core/util/simpleFeature").Feature): void;
             clearFeatureSelection(): void;
@@ -676,7 +752,13 @@ export default class WigglePlugin extends Plugin {
             reload(): void;
             setContextMenuFeature(feature?: import("@jbrowse/core/util/simpleFeature").Feature | undefined): void;
         } & {
-            regionCannotBeRenderedText(_region: import("@jbrowse/core/util/types").Region): "" | "Zoom in to see features";
+            readonly regionTooLarge: boolean;
+            readonly regionTooLargeReason: string;
+        } & {
+            reload(): Promise<void>;
+            afterAttach(): void;
+        } & {
+            regionCannotBeRenderedText(_region: import("@jbrowse/core/util/types").Region): "" | "Force load to see features";
             regionCannotBeRendered(_region: import("@jbrowse/core/util/types").Region): JSX.Element | undefined;
             trackMenuItems(): import("@jbrowse/core/ui").MenuItem[];
             contextMenuItems(): {
@@ -690,7 +772,7 @@ export default class WigglePlugin extends Plugin {
                 overrideHeight: number;
             }): Promise<JSX.Element>;
         } & {
-            ready: boolean;
+            statsReady: boolean;
             message: string | undefined;
             stats: {
                 scoreMin: number;
@@ -703,6 +785,8 @@ export default class WigglePlugin extends Plugin {
                 scoreMax: number;
             }): void;
             setColor(color: string): void;
+            setPosColor(color: string): void;
+            setNegColor(color: string): void;
             setLoading(aborter: AbortController): void;
             selectFeature(feature: import("@jbrowse/core/util/simpleFeature").Feature): void;
             setResolution(res: number): void;
@@ -722,11 +806,12 @@ export default class WigglePlugin extends Plugin {
             readonly rendererTypeName: string;
             readonly filters: undefined;
             readonly scaleType: any;
-            readonly filled: any;
             readonly maxScore: any;
             readonly minScore: any;
+        } & {
             readonly rendererConfig: any;
         } & {
+            readonly filled: any;
             readonly summaryScoreModeSetting: any;
             readonly domain: number[];
             readonly needsScalebar: boolean;
@@ -769,6 +854,7 @@ export default class WigglePlugin extends Plugin {
             rpcDriverName: string | undefined;
             height: number;
             userBpPerPxLimit: number | undefined;
+            userByteSizeLimit: number | undefined;
         } & import("mobx-state-tree")._NotCustomized>;
     };
 }