@jbrowse/plugin-alignments 2.18.0 → 3.0.1
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/dist/AlignmentsFeatureDetail/AlignmentsFeatureDetail.d.ts +1 -2
- package/dist/AlignmentsFeatureDetail/AlignmentsFeatureDetail.js +20 -13
- package/dist/AlignmentsFeatureDetail/Flags.d.ts +1 -2
- package/dist/AlignmentsFeatureDetail/Flags.js +6 -8
- package/dist/AlignmentsFeatureDetail/Formatter.d.ts +1 -2
- package/dist/AlignmentsFeatureDetail/Formatter.js +11 -36
- package/dist/AlignmentsFeatureDetail/LaunchPairedEndBreakpointSplitViewPanel.d.ts +1 -2
- package/dist/AlignmentsFeatureDetail/LaunchPairedEndBreakpointSplitViewPanel.js +44 -47
- package/dist/AlignmentsFeatureDetail/LaunchSupplementaryAlignmentBreakpointSplitViewPanel.d.ts +1 -2
- package/dist/AlignmentsFeatureDetail/LaunchSupplementaryAlignmentBreakpointSplitViewPanel.js +27 -31
- package/dist/AlignmentsFeatureDetail/LinkedPairedAlignments.d.ts +1 -2
- package/dist/AlignmentsFeatureDetail/LinkedPairedAlignments.js +2 -2
- package/dist/AlignmentsFeatureDetail/PairLink.d.ts +1 -2
- package/dist/AlignmentsFeatureDetail/PairLink.js +3 -6
- package/dist/AlignmentsFeatureDetail/SupplementaryAlignments.d.ts +1 -2
- package/dist/AlignmentsFeatureDetail/SupplementaryAlignments.js +2 -4
- package/dist/AlignmentsFeatureDetail/SupplementaryAlignmentsLocStrings.d.ts +1 -2
- package/dist/AlignmentsFeatureDetail/SupplementaryAlignmentsLocStrings.js +21 -27
- package/dist/AlignmentsFeatureDetail/index.js +17 -7
- package/dist/BamAdapter/index.js +17 -7
- package/dist/CramAdapter/CramAdapter.js +7 -2
- package/dist/CramAdapter/CramTestAdapters.d.ts +1 -1
- package/dist/CramAdapter/CramTestAdapters.js +2 -1
- package/dist/CramAdapter/index.js +17 -7
- package/dist/GuessAlignmentsTypes/index.js +19 -34
- package/dist/HtsgetBamAdapter/index.js +17 -7
- package/dist/LinearAlignmentsDisplay/components/AlignmentsDisplay.d.ts +1 -2
- package/dist/LinearAlignmentsDisplay/components/AlignmentsDisplay.js +8 -16
- package/dist/LinearAlignmentsDisplay/model.d.ts +1 -2
- package/dist/LinearAlignmentsDisplay/model.js +5 -7
- package/dist/LinearPileupDisplay/SharedLinearPileupDisplayMixin.d.ts +21 -7
- package/dist/LinearPileupDisplay/SharedLinearPileupDisplayMixin.js +40 -15
- package/dist/LinearPileupDisplay/components/ColorByTagDialog.d.ts +1 -2
- package/dist/LinearPileupDisplay/components/ColorByTagDialog.js +10 -39
- package/dist/LinearPileupDisplay/components/GroupByDialog.d.ts +1 -2
- package/dist/LinearPileupDisplay/components/GroupByDialog.js +82 -121
- package/dist/LinearPileupDisplay/components/LinearPileupDisplayBlurb.d.ts +1 -2
- package/dist/LinearPileupDisplay/components/LinearPileupDisplayBlurb.js +2 -6
- package/dist/LinearPileupDisplay/components/SetFeatureHeightDialog.d.ts +1 -2
- package/dist/LinearPileupDisplay/components/SetFeatureHeightDialog.js +13 -42
- package/dist/LinearPileupDisplay/components/SetMaxHeightDialog.d.ts +1 -2
- package/dist/LinearPileupDisplay/components/SetMaxHeightDialog.js +10 -38
- package/dist/LinearPileupDisplay/components/SortByTagDialog.d.ts +1 -2
- package/dist/LinearPileupDisplay/components/SortByTagDialog.js +15 -44
- package/dist/LinearPileupDisplay/model.d.ts +21 -7
- package/dist/LinearPileupDisplay/model.js +19 -8
- package/dist/LinearReadArcsDisplay/components/ReactComponent.d.ts +1 -2
- package/dist/LinearReadArcsDisplay/components/ReactComponent.js +4 -27
- package/dist/LinearReadArcsDisplay/index.js +17 -7
- package/dist/LinearReadArcsDisplay/model.d.ts +1 -1
- package/dist/LinearReadArcsDisplay/model.js +17 -7
- package/dist/LinearReadCloudDisplay/components/ReactComponent.d.ts +1 -2
- package/dist/LinearReadCloudDisplay/components/ReactComponent.js +4 -27
- package/dist/LinearReadCloudDisplay/index.js +17 -7
- package/dist/LinearReadCloudDisplay/model.d.ts +1 -1
- package/dist/LinearReadCloudDisplay/model.js +17 -7
- package/dist/LinearSNPCoverageDisplay/components/Tooltip.d.ts +1 -2
- package/dist/LinearSNPCoverageDisplay/components/Tooltip.js +15 -54
- package/dist/LinearSNPCoverageDisplay/model.d.ts +4 -4
- package/dist/LinearSNPCoverageDisplay/model.js +49 -35
- package/dist/MismatchParser/cigarToMismatches.d.ts +1 -2
- package/dist/MismatchParser/index.d.ts +1 -2
- package/dist/MismatchParser/mdToMismatches.d.ts +1 -2
- package/dist/PileupRenderer/PileupRenderer.d.ts +4 -4
- package/dist/PileupRenderer/PileupRenderer.js +17 -7
- package/dist/PileupRenderer/components/PileupRendering.d.ts +1 -2
- package/dist/PileupRenderer/components/PileupRendering.js +15 -40
- package/dist/PileupRenderer/configSchema.d.ts +5 -0
- package/dist/PileupRenderer/configSchema.js +5 -0
- package/dist/PileupRenderer/makeImageData.js +2 -0
- package/dist/PileupRenderer/renderMismatches.d.ts +2 -1
- package/dist/PileupRenderer/renderMismatches.js +18 -13
- package/dist/SNPCoverageAdapter/index.js +17 -7
- package/dist/SNPCoverageAdapter/processModifications.js +1 -1
- package/dist/SNPCoverageRenderer/SNPCoverageRenderer.d.ts +1 -18
- package/dist/SNPCoverageRenderer/SNPCoverageRenderer.js +35 -264
- package/dist/SNPCoverageRenderer/configSchema.d.ts +3 -3
- package/dist/SNPCoverageRenderer/configSchema.js +3 -3
- package/dist/SNPCoverageRenderer/makeImage.d.ts +2 -0
- package/dist/SNPCoverageRenderer/makeImage.js +270 -0
- package/dist/SNPCoverageRenderer/types.d.ts +19 -0
- package/dist/SNPCoverageRenderer/types.js +2 -0
- package/dist/index.js +17 -7
- package/dist/shared/components/BaseDisplayComponent.d.ts +1 -2
- package/dist/shared/components/BaseDisplayComponent.js +6 -13
- package/dist/shared/components/FilterByTagDialog.d.ts +1 -2
- package/dist/shared/components/FilterByTagDialog.js +42 -92
- package/dist/shared/renderSvgUtil.d.ts +1 -2
- package/dist/shared/renderSvgUtil.js +20 -17
- package/esm/AlignmentsFeatureDetail/AlignmentsFeatureDetail.d.ts +1 -2
- package/esm/AlignmentsFeatureDetail/AlignmentsFeatureDetail.js +3 -6
- package/esm/AlignmentsFeatureDetail/Flags.d.ts +1 -2
- package/esm/AlignmentsFeatureDetail/Flags.js +6 -8
- package/esm/AlignmentsFeatureDetail/Formatter.d.ts +1 -2
- package/esm/AlignmentsFeatureDetail/Formatter.js +11 -13
- package/esm/AlignmentsFeatureDetail/LaunchPairedEndBreakpointSplitViewPanel.d.ts +1 -2
- package/esm/AlignmentsFeatureDetail/LaunchPairedEndBreakpointSplitViewPanel.js +27 -40
- package/esm/AlignmentsFeatureDetail/LaunchSupplementaryAlignmentBreakpointSplitViewPanel.d.ts +1 -2
- package/esm/AlignmentsFeatureDetail/LaunchSupplementaryAlignmentBreakpointSplitViewPanel.js +10 -24
- package/esm/AlignmentsFeatureDetail/LinkedPairedAlignments.d.ts +1 -2
- package/esm/AlignmentsFeatureDetail/LinkedPairedAlignments.js +2 -2
- package/esm/AlignmentsFeatureDetail/PairLink.d.ts +1 -2
- package/esm/AlignmentsFeatureDetail/PairLink.js +3 -3
- package/esm/AlignmentsFeatureDetail/SupplementaryAlignments.d.ts +1 -2
- package/esm/AlignmentsFeatureDetail/SupplementaryAlignments.js +2 -4
- package/esm/AlignmentsFeatureDetail/SupplementaryAlignmentsLocStrings.d.ts +1 -2
- package/esm/AlignmentsFeatureDetail/SupplementaryAlignmentsLocStrings.js +21 -24
- package/esm/CramAdapter/CramAdapter.js +7 -2
- package/esm/CramAdapter/CramTestAdapters.d.ts +1 -1
- package/esm/CramAdapter/CramTestAdapters.js +2 -1
- package/esm/GuessAlignmentsTypes/index.js +19 -34
- package/esm/LinearAlignmentsDisplay/components/AlignmentsDisplay.d.ts +1 -2
- package/esm/LinearAlignmentsDisplay/components/AlignmentsDisplay.js +8 -13
- package/esm/LinearAlignmentsDisplay/model.d.ts +1 -2
- package/esm/LinearAlignmentsDisplay/model.js +5 -7
- package/esm/LinearPileupDisplay/SharedLinearPileupDisplayMixin.d.ts +21 -7
- package/esm/LinearPileupDisplay/SharedLinearPileupDisplayMixin.js +23 -8
- package/esm/LinearPileupDisplay/components/ColorByTagDialog.d.ts +1 -2
- package/esm/LinearPileupDisplay/components/ColorByTagDialog.js +10 -16
- package/esm/LinearPileupDisplay/components/GroupByDialog.d.ts +1 -2
- package/esm/LinearPileupDisplay/components/GroupByDialog.js +82 -98
- package/esm/LinearPileupDisplay/components/LinearPileupDisplayBlurb.d.ts +1 -2
- package/esm/LinearPileupDisplay/components/LinearPileupDisplayBlurb.js +2 -3
- package/esm/LinearPileupDisplay/components/SetFeatureHeightDialog.d.ts +1 -2
- package/esm/LinearPileupDisplay/components/SetFeatureHeightDialog.js +13 -19
- package/esm/LinearPileupDisplay/components/SetMaxHeightDialog.d.ts +1 -2
- package/esm/LinearPileupDisplay/components/SetMaxHeightDialog.js +10 -15
- package/esm/LinearPileupDisplay/components/SortByTagDialog.d.ts +1 -2
- package/esm/LinearPileupDisplay/components/SortByTagDialog.js +15 -21
- package/esm/LinearPileupDisplay/model.d.ts +21 -7
- package/esm/LinearPileupDisplay/model.js +2 -1
- package/esm/LinearReadArcsDisplay/components/ReactComponent.d.ts +1 -2
- package/esm/LinearReadArcsDisplay/components/ReactComponent.js +4 -4
- package/esm/LinearReadArcsDisplay/model.d.ts +1 -1
- package/esm/LinearReadCloudDisplay/components/ReactComponent.d.ts +1 -2
- package/esm/LinearReadCloudDisplay/components/ReactComponent.js +4 -4
- package/esm/LinearReadCloudDisplay/model.d.ts +1 -1
- package/esm/LinearSNPCoverageDisplay/components/Tooltip.d.ts +1 -2
- package/esm/LinearSNPCoverageDisplay/components/Tooltip.js +15 -51
- package/esm/LinearSNPCoverageDisplay/model.d.ts +4 -4
- package/esm/LinearSNPCoverageDisplay/model.js +32 -28
- package/esm/MismatchParser/cigarToMismatches.d.ts +1 -2
- package/esm/MismatchParser/index.d.ts +1 -2
- package/esm/MismatchParser/mdToMismatches.d.ts +1 -2
- package/esm/PileupRenderer/PileupRenderer.d.ts +4 -4
- package/esm/PileupRenderer/components/PileupRendering.d.ts +1 -2
- package/esm/PileupRenderer/components/PileupRendering.js +15 -17
- package/esm/PileupRenderer/configSchema.d.ts +5 -0
- package/esm/PileupRenderer/configSchema.js +5 -0
- package/esm/PileupRenderer/makeImageData.js +2 -0
- package/esm/PileupRenderer/renderMismatches.d.ts +2 -1
- package/esm/PileupRenderer/renderMismatches.js +18 -13
- package/esm/SNPCoverageAdapter/processModifications.js +1 -1
- package/esm/SNPCoverageRenderer/SNPCoverageRenderer.d.ts +1 -18
- package/esm/SNPCoverageRenderer/SNPCoverageRenderer.js +3 -265
- package/esm/SNPCoverageRenderer/configSchema.d.ts +3 -3
- package/esm/SNPCoverageRenderer/configSchema.js +3 -3
- package/esm/SNPCoverageRenderer/makeImage.d.ts +2 -0
- package/esm/SNPCoverageRenderer/makeImage.js +267 -0
- package/esm/SNPCoverageRenderer/types.d.ts +19 -0
- package/esm/SNPCoverageRenderer/types.js +1 -0
- package/esm/shared/components/BaseDisplayComponent.d.ts +1 -2
- package/esm/shared/components/BaseDisplayComponent.js +6 -10
- package/esm/shared/components/FilterByTagDialog.d.ts +1 -2
- package/esm/shared/components/FilterByTagDialog.js +42 -69
- package/esm/shared/renderSvgUtil.d.ts +1 -2
- package/esm/shared/renderSvgUtil.js +3 -7
- package/package.json +13 -13
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import { readConfObject } from '@jbrowse/core/configuration';
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import { createJBrowseTheme } from '@jbrowse/core/ui';
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import { bpSpanPx, featureSpanPx } from '@jbrowse/core/util';
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import { checkStopToken } from '@jbrowse/core/util/stopToken';
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import { YSCALEBAR_LABEL_OFFSET, getOrigin, getScale, } from '@jbrowse/plugin-wiggle';
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import { alphaColor } from '../shared/util';
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const INTERBASE_INDICATOR_WIDTH = 7;
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const INTERBASE_INDICATOR_HEIGHT = 4.5;
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const MINIMUM_INTERBASE_INDICATOR_READ_DEPTH = 7;
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const complementBase = {
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C: 'G',
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G: 'C',
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A: 'T',
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T: 'A',
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};
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const fudgeFactor = 0.6;
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export async function makeImage(ctx, props) {
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var _a, _b, _c, _d, _e, _f, _g, _h, _j, _k;
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const { features, regions, bpPerPx, colorBy, displayCrossHatches, visibleModifications = {}, scaleOpts, height: unadjustedHeight, theme: configTheme, config: cfg, ticks, stopToken, } = props;
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const theme = createJBrowseTheme(configTheme);
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const region = regions[0];
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const width = (region.end - region.start) / bpPerPx;
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const offset = YSCALEBAR_LABEL_OFFSET;
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const height = unadjustedHeight - offset * 2;
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const opts = { ...scaleOpts, range: [0, height] };
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const viewScale = getScale(opts);
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const indicatorViewScale = getScale({
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...opts,
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range: [0, height / 2],
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scaleType: 'linear',
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});
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const originY = getOrigin(scaleOpts.scaleType);
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const originLinear = getOrigin('linear');
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const indicatorThreshold = readConfObject(cfg, 'indicatorThreshold');
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const showInterbaseCounts = readConfObject(cfg, 'showInterbaseCounts');
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const showArcs = readConfObject(cfg, 'showArcs');
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const showInterbaseIndicators = readConfObject(cfg, 'showInterbaseIndicators');
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const toY = (n) => height - (viewScale(n) || 0) + offset;
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const toHeight = (n) => toY(originY) - toY(n);
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const toY2 = (n) => height - (indicatorViewScale(n) || 0) + offset;
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const toHeight2 = (n) => toY2(originLinear) - toY2(n);
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const { bases } = theme.palette;
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const colorForBase = {
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A: bases.A.main,
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C: bases.C.main,
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G: bases.G.main,
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T: bases.T.main,
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insertion: 'purple',
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softclip: 'blue',
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hardclip: 'red',
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total: readConfObject(cfg, 'color'),
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mod_NONE: 'blue',
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cpg_meth: 'red',
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cpg_unmeth: 'blue',
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};
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const feats = [...features.values()];
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ctx.fillStyle = colorForBase.total;
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let start = performance.now();
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for (const feature of feats) {
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if (feature.get('type') === 'skip') {
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continue;
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}
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const [leftPx, rightPx] = featureSpanPx(feature, region, bpPerPx);
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const w = rightPx - leftPx + fudgeFactor;
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const score = feature.get('score');
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ctx.fillRect(leftPx, toY(score), w, toHeight(score));
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if (performance.now() - start > 400) {
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checkStopToken(stopToken);
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start = performance.now();
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}
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}
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let prevTotal = 0;
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const extraHorizontallyFlippedOffset = region.reversed ? 1 / bpPerPx : 0;
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const drawingModifications = colorBy.type === 'modifications';
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const drawingMethylation = colorBy.type === 'methylation';
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const isolatedModification = (_a = colorBy.modifications) === null || _a === void 0 ? void 0 : _a.isolatedModification;
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start = performance.now();
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for (const feature of feats) {
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const now = performance.now();
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if (now - start > 400) {
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checkStopToken(stopToken);
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}
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if (feature.get('type') === 'skip') {
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continue;
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}
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const [leftPx, rightPx] = featureSpanPx(feature, region, bpPerPx);
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const snpinfo = feature.get('snpinfo');
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const w = Math.max(rightPx - leftPx, 1);
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const score0 = feature.get('score');
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if (drawingModifications) {
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let curr = 0;
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const refbase = (_b = snpinfo.refbase) === null || _b === void 0 ? void 0 : _b.toUpperCase();
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const { nonmods, mods, snps, ref } = snpinfo;
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for (const m of Object.keys(nonmods).sort().reverse()) {
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const mod = visibleModifications[m.replace('nonmod_', '')] ||
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visibleModifications[m.replace('mod_', '')];
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if (!mod) {
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console.warn(`${m} not known yet`);
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continue;
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}
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if (isolatedModification && mod.type !== isolatedModification) {
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continue;
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}
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const cmp = complementBase[mod.base];
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const detectable = mod.base === 'N'
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? score0
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: (((_c = snps[mod.base]) === null || _c === void 0 ? void 0 : _c.entryDepth) || 0) +
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(((_d = snps[cmp]) === null || _d === void 0 ? void 0 : _d.entryDepth) || 0) +
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(refbase === mod.base ? ref['1'] : 0) +
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(refbase === cmp ? ref['-1'] : 0);
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const modifiable = mod.base === 'N'
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? score0
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: (((_e = snps[mod.base]) === null || _e === void 0 ? void 0 : _e.entryDepth) || 0) +
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(((_f = snps[cmp]) === null || _f === void 0 ? void 0 : _f.entryDepth) || 0) +
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(refbase === mod.base ? ref.entryDepth : 0) +
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(refbase === cmp ? ref.entryDepth : 0);
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const { entryDepth, avgProbability = 0 } = snpinfo.nonmods[m];
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const modFraction = (modifiable / score0) * (entryDepth / detectable);
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const nonModColor = 'blue';
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const c = alphaColor(nonModColor, avgProbability);
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const height = toHeight(score0);
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const bottom = toY(score0) + height;
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ctx.fillStyle = c;
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ctx.fillRect(Math.round(leftPx), bottom - (curr + modFraction * height), w, modFraction * height);
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curr += modFraction * height;
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}
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for (const m of Object.keys(mods).sort().reverse()) {
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const mod = visibleModifications[m.replace('mod_', '')];
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if (!mod) {
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console.warn(`${m} not known yet`);
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continue;
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}
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if (isolatedModification && mod.type !== isolatedModification) {
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continue;
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}
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const cmp = complementBase[mod.base];
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const detectable = mod.base === 'N'
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? score0
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: (((_g = snps[mod.base]) === null || _g === void 0 ? void 0 : _g.entryDepth) || 0) +
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(((_h = snps[cmp]) === null || _h === void 0 ? void 0 : _h.entryDepth) || 0) +
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(refbase === mod.base ? ref['1'] : 0) +
|
|
142
|
+
(refbase === cmp ? ref['-1'] : 0);
|
|
143
|
+
const modifiable = mod.base === 'N'
|
|
144
|
+
? score0
|
|
145
|
+
: (((_j = snps[mod.base]) === null || _j === void 0 ? void 0 : _j.entryDepth) || 0) +
|
|
146
|
+
(((_k = snps[cmp]) === null || _k === void 0 ? void 0 : _k.entryDepth) || 0) +
|
|
147
|
+
(refbase === mod.base ? ref.entryDepth : 0) +
|
|
148
|
+
(refbase === cmp ? ref.entryDepth : 0);
|
|
149
|
+
const { entryDepth, avgProbability = 0 } = mods[m];
|
|
150
|
+
const modFraction = (modifiable / score0) * (entryDepth / detectable);
|
|
151
|
+
const baseColor = mod.color || 'black';
|
|
152
|
+
const c = alphaColor(baseColor, avgProbability);
|
|
153
|
+
const height = toHeight(score0);
|
|
154
|
+
const bottom = toY(score0) + height;
|
|
155
|
+
ctx.fillStyle = c;
|
|
156
|
+
ctx.fillRect(Math.round(leftPx), bottom - (curr + modFraction * height), w, modFraction * height);
|
|
157
|
+
curr += modFraction * height;
|
|
158
|
+
}
|
|
159
|
+
}
|
|
160
|
+
else if (drawingMethylation) {
|
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161
|
+
const { depth, nonmods, mods } = snpinfo;
|
|
162
|
+
let curr = 0;
|
|
163
|
+
for (const base of Object.keys(mods).sort().reverse()) {
|
|
164
|
+
const { entryDepth } = mods[base];
|
|
165
|
+
const height = toHeight(score0);
|
|
166
|
+
const bottom = toY(score0) + height;
|
|
167
|
+
ctx.fillStyle = colorForBase[base] || 'black';
|
|
168
|
+
ctx.fillRect(Math.round(leftPx), bottom - ((entryDepth + curr) / depth) * height, w, (entryDepth / depth) * height);
|
|
169
|
+
curr += entryDepth;
|
|
170
|
+
}
|
|
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|
+
for (const base of Object.keys(nonmods).sort().reverse()) {
|
|
172
|
+
const { entryDepth } = nonmods[base];
|
|
173
|
+
const height = toHeight(score0);
|
|
174
|
+
const bottom = toY(score0) + height;
|
|
175
|
+
ctx.fillStyle = colorForBase[base] || 'black';
|
|
176
|
+
ctx.fillRect(Math.round(leftPx), bottom - ((entryDepth + curr) / depth) * height, w, (entryDepth / depth) * height);
|
|
177
|
+
curr += entryDepth;
|
|
178
|
+
}
|
|
179
|
+
}
|
|
180
|
+
else {
|
|
181
|
+
const { depth, snps } = snpinfo;
|
|
182
|
+
let curr = 0;
|
|
183
|
+
for (const base of Object.keys(snps).sort().reverse()) {
|
|
184
|
+
const { entryDepth } = snps[base];
|
|
185
|
+
const height = toHeight(score0);
|
|
186
|
+
const bottom = toY(score0) + height;
|
|
187
|
+
ctx.fillStyle = colorForBase[base] || 'black';
|
|
188
|
+
ctx.fillRect(Math.round(leftPx), bottom - ((entryDepth + curr) / depth) * height, w, (entryDepth / depth) * height);
|
|
189
|
+
curr += entryDepth;
|
|
190
|
+
}
|
|
191
|
+
}
|
|
192
|
+
const interbaseEvents = Object.keys(snpinfo.noncov);
|
|
193
|
+
if (showInterbaseCounts) {
|
|
194
|
+
let curr = 0;
|
|
195
|
+
for (const base of interbaseEvents) {
|
|
196
|
+
const { entryDepth } = snpinfo.noncov[base];
|
|
197
|
+
const r = 0.6;
|
|
198
|
+
ctx.fillStyle = colorForBase[base];
|
|
199
|
+
ctx.fillRect(leftPx - r + extraHorizontallyFlippedOffset, INTERBASE_INDICATOR_HEIGHT + toHeight2(curr), r * 2, toHeight2(entryDepth));
|
|
200
|
+
curr += entryDepth;
|
|
201
|
+
}
|
|
202
|
+
}
|
|
203
|
+
if (showInterbaseIndicators) {
|
|
204
|
+
let accum = 0;
|
|
205
|
+
let max = 0;
|
|
206
|
+
let maxBase = '';
|
|
207
|
+
for (const base of interbaseEvents) {
|
|
208
|
+
const { entryDepth } = snpinfo.noncov[base];
|
|
209
|
+
accum += entryDepth;
|
|
210
|
+
if (entryDepth > max) {
|
|
211
|
+
max = entryDepth;
|
|
212
|
+
maxBase = base;
|
|
213
|
+
}
|
|
214
|
+
}
|
|
215
|
+
const indicatorComparatorScore = Math.max(score0, prevTotal);
|
|
216
|
+
if (accum > indicatorComparatorScore * indicatorThreshold &&
|
|
217
|
+
indicatorComparatorScore > MINIMUM_INTERBASE_INDICATOR_READ_DEPTH) {
|
|
218
|
+
ctx.fillStyle = colorForBase[maxBase];
|
|
219
|
+
ctx.beginPath();
|
|
220
|
+
const l = leftPx + extraHorizontallyFlippedOffset;
|
|
221
|
+
ctx.moveTo(l - INTERBASE_INDICATOR_WIDTH / 2, 0);
|
|
222
|
+
ctx.lineTo(l + INTERBASE_INDICATOR_WIDTH / 2, 0);
|
|
223
|
+
ctx.lineTo(l, INTERBASE_INDICATOR_HEIGHT);
|
|
224
|
+
ctx.fill();
|
|
225
|
+
}
|
|
226
|
+
}
|
|
227
|
+
prevTotal = score0;
|
|
228
|
+
}
|
|
229
|
+
if (showArcs) {
|
|
230
|
+
for (const f of feats) {
|
|
231
|
+
if (f.get('type') !== 'skip') {
|
|
232
|
+
continue;
|
|
233
|
+
}
|
|
234
|
+
const s = f.get('start');
|
|
235
|
+
const e = f.get('end');
|
|
236
|
+
const [left, right] = bpSpanPx(s, e, region, bpPerPx);
|
|
237
|
+
ctx.beginPath();
|
|
238
|
+
const effectiveStrand = f.get('effectiveStrand');
|
|
239
|
+
const pos = 'rgba(255,200,200,0.7)';
|
|
240
|
+
const neg = 'rgba(200,200,255,0.7)';
|
|
241
|
+
const neutral = 'rgba(200,200,200,0.7)';
|
|
242
|
+
if (effectiveStrand === 1) {
|
|
243
|
+
ctx.strokeStyle = pos;
|
|
244
|
+
}
|
|
245
|
+
else if (effectiveStrand === -1) {
|
|
246
|
+
ctx.strokeStyle = neg;
|
|
247
|
+
}
|
|
248
|
+
else {
|
|
249
|
+
ctx.strokeStyle = neutral;
|
|
250
|
+
}
|
|
251
|
+
ctx.lineWidth = Math.log(f.get('score') + 1);
|
|
252
|
+
ctx.moveTo(left, height - offset * 2);
|
|
253
|
+
ctx.bezierCurveTo(left, 0, right, 0, right, height - offset * 2);
|
|
254
|
+
ctx.stroke();
|
|
255
|
+
}
|
|
256
|
+
}
|
|
257
|
+
if (displayCrossHatches) {
|
|
258
|
+
ctx.lineWidth = 1;
|
|
259
|
+
ctx.strokeStyle = 'rgba(140,140,140,0.8)';
|
|
260
|
+
for (const tick of ticks.values) {
|
|
261
|
+
ctx.beginPath();
|
|
262
|
+
ctx.moveTo(0, Math.round(toY(tick)));
|
|
263
|
+
ctx.lineTo(width, Math.round(toY(tick)));
|
|
264
|
+
ctx.stroke();
|
|
265
|
+
}
|
|
266
|
+
}
|
|
267
|
+
}
|
|
@@ -0,0 +1,19 @@
|
|
|
1
|
+
import type { ColorBy, ModificationTypeWithColor } from '../shared/types';
|
|
2
|
+
import type { RenderArgsDeserialized as FeatureRenderArgsDeserialized } from '@jbrowse/core/pluggableElementTypes/renderers/FeatureRendererType';
|
|
3
|
+
import type { Feature } from '@jbrowse/core/util';
|
|
4
|
+
import type { ScaleOpts } from '@jbrowse/plugin-wiggle';
|
|
5
|
+
export interface RenderArgsDeserialized extends FeatureRenderArgsDeserialized {
|
|
6
|
+
bpPerPx: number;
|
|
7
|
+
height: number;
|
|
8
|
+
highResolutionScaling: number;
|
|
9
|
+
scaleOpts: ScaleOpts;
|
|
10
|
+
}
|
|
11
|
+
export interface RenderArgsDeserializedWithFeatures extends RenderArgsDeserialized {
|
|
12
|
+
features: Map<string, Feature>;
|
|
13
|
+
ticks: {
|
|
14
|
+
values: number[];
|
|
15
|
+
};
|
|
16
|
+
displayCrossHatches: boolean;
|
|
17
|
+
visibleModifications?: Record<string, ModificationTypeWithColor>;
|
|
18
|
+
colorBy: ColorBy;
|
|
19
|
+
}
|
|
@@ -0,0 +1 @@
|
|
|
1
|
+
export {};
|
|
@@ -1,8 +1,7 @@
|
|
|
1
|
-
import React from 'react';
|
|
2
1
|
import type { LinearReadArcsDisplayModel } from '../../LinearReadArcsDisplay/model';
|
|
3
2
|
import type { LinearReadCloudDisplayModel } from '../../LinearReadCloudDisplay/model';
|
|
4
3
|
declare const BaseDisplayComponent: ({ model, children, }: {
|
|
5
4
|
model: LinearReadArcsDisplayModel | LinearReadCloudDisplayModel;
|
|
6
5
|
children?: React.ReactNode;
|
|
7
|
-
}) =>
|
|
6
|
+
}) => import("react/jsx-runtime").JSX.Element | null;
|
|
8
7
|
export default BaseDisplayComponent;
|
|
@@ -1,4 +1,4 @@
|
|
|
1
|
-
import
|
|
1
|
+
import { jsx as _jsx, jsxs as _jsxs } from "react/jsx-runtime";
|
|
2
2
|
import { LoadingEllipses } from '@jbrowse/core/ui';
|
|
3
3
|
import { getContainingView } from '@jbrowse/core/util';
|
|
4
4
|
import { BlockMsg } from '@jbrowse/plugin-linear-genome-view';
|
|
@@ -20,27 +20,23 @@ const useStyles = makeStyles()(theme => ({
|
|
|
20
20
|
}));
|
|
21
21
|
const BlockError = observer(function ({ model, }) {
|
|
22
22
|
const { error } = model;
|
|
23
|
-
return (
|
|
24
|
-
React.createElement(Button, { "data-testid": "reload_button", onClick: () => {
|
|
23
|
+
return (_jsx(BlockMsg, { message: `${error}`, severity: "error", action: _jsx(Tooltip, { title: "Reload", children: _jsx(Button, { "data-testid": "reload_button", onClick: () => {
|
|
25
24
|
model.reload();
|
|
26
|
-
}
|
|
25
|
+
}, children: "Reload" }) }) }));
|
|
27
26
|
});
|
|
28
27
|
const BaseDisplayComponent = observer(function ({ model, children, }) {
|
|
29
28
|
const { error, regionTooLarge } = model;
|
|
30
|
-
return error ? (
|
|
29
|
+
return error ? (_jsx(BlockError, { model: model })) : regionTooLarge ? (model.regionCannotBeRendered()) : (_jsx(DataDisplay, { model: model, children: children }));
|
|
31
30
|
});
|
|
32
31
|
const DataDisplay = observer(function ({ model, children, }) {
|
|
33
32
|
const { drawn, loading } = model;
|
|
34
33
|
const view = getContainingView(model);
|
|
35
34
|
const left = (model.lastDrawnOffsetPx || 0) - view.offsetPx;
|
|
36
|
-
return (
|
|
37
|
-
React.createElement("div", { style: { position: 'absolute', left } }, children),
|
|
38
|
-
left !== 0 || loading ? React.createElement(LoadingBar, { model: model }) : null));
|
|
35
|
+
return (_jsxs("div", { "data-testid": `drawn-${drawn}`, children: [_jsx("div", { style: { position: 'absolute', left }, children: children }), left !== 0 || loading ? _jsx(LoadingBar, { model: model }) : null] }));
|
|
39
36
|
});
|
|
40
37
|
const LoadingBar = observer(function ({ model, }) {
|
|
41
38
|
const { classes } = useStyles();
|
|
42
39
|
const { message } = model;
|
|
43
|
-
return (
|
|
44
|
-
React.createElement(LoadingEllipses, { message: message })));
|
|
40
|
+
return (_jsx("div", { className: classes.loading, children: _jsx(LoadingEllipses, { message: message }) }));
|
|
45
41
|
});
|
|
46
42
|
export default BaseDisplayComponent;
|
|
@@ -1,4 +1,3 @@
|
|
|
1
|
-
import React from 'react';
|
|
2
1
|
import type { FilterBy } from '../types';
|
|
3
2
|
declare const FilterByTagDialog: (props: {
|
|
4
3
|
model: {
|
|
@@ -6,5 +5,5 @@ declare const FilterByTagDialog: (props: {
|
|
|
6
5
|
setFilterBy: (arg: FilterBy) => void;
|
|
7
6
|
};
|
|
8
7
|
handleClose: () => void;
|
|
9
|
-
}) =>
|
|
8
|
+
}) => import("react/jsx-runtime").JSX.Element;
|
|
10
9
|
export default FilterByTagDialog;
|
|
@@ -1,4 +1,5 @@
|
|
|
1
|
-
import
|
|
1
|
+
import { jsx as _jsx, jsxs as _jsxs, Fragment as _Fragment } from "react/jsx-runtime";
|
|
2
|
+
import { useState } from 'react';
|
|
2
3
|
import { Dialog } from '@jbrowse/core/ui';
|
|
3
4
|
import { Button, DialogActions, DialogContent, Link, Paper, TextField, Typography, } from '@mui/material';
|
|
4
5
|
import { observer } from 'mobx-react';
|
|
@@ -28,24 +29,20 @@ const flagNames = [
|
|
|
28
29
|
];
|
|
29
30
|
function Bitmask(props) {
|
|
30
31
|
const { flag = 0, setFlag } = props;
|
|
31
|
-
return (
|
|
32
|
-
|
|
33
|
-
|
|
34
|
-
|
|
35
|
-
|
|
36
|
-
|
|
37
|
-
|
|
38
|
-
|
|
39
|
-
|
|
40
|
-
|
|
41
|
-
|
|
42
|
-
|
|
43
|
-
|
|
44
|
-
|
|
45
|
-
}
|
|
46
|
-
} }),
|
|
47
|
-
React.createElement("label", { htmlFor: key }, name)));
|
|
48
|
-
})));
|
|
32
|
+
return (_jsxs(_Fragment, { children: [_jsx(TextField, { type: "number", value: flag, onChange: event => {
|
|
33
|
+
setFlag(+event.target.value);
|
|
34
|
+
} }), flagNames.map((name, index) => {
|
|
35
|
+
const val = flag & (1 << index);
|
|
36
|
+
const key = `${name}_${val}`;
|
|
37
|
+
return (_jsxs("div", { children: [_jsx("input", { type: "checkbox", checked: Boolean(val), onChange: event => {
|
|
38
|
+
if (event.target.checked) {
|
|
39
|
+
setFlag(flag | (1 << index));
|
|
40
|
+
}
|
|
41
|
+
else {
|
|
42
|
+
setFlag(flag & ~(1 << index));
|
|
43
|
+
}
|
|
44
|
+
} }), _jsx("label", { htmlFor: key, children: name })] }, key));
|
|
45
|
+
})] }));
|
|
49
46
|
}
|
|
50
47
|
const FilterByTagDialog = observer(function (props) {
|
|
51
48
|
var _a, _b;
|
|
@@ -59,55 +56,31 @@ const FilterByTagDialog = observer(function (props) {
|
|
|
59
56
|
const [readName, setReadName] = useState(filterBy.readName || '');
|
|
60
57
|
const validTag = /^[A-Za-z][A-Za-z0-9]$/.exec(tag);
|
|
61
58
|
const site = 'https://broadinstitute.github.io/picard/explain-flags.html';
|
|
62
|
-
return (
|
|
63
|
-
|
|
64
|
-
|
|
65
|
-
|
|
66
|
-
|
|
67
|
-
|
|
68
|
-
|
|
69
|
-
|
|
70
|
-
|
|
71
|
-
|
|
72
|
-
|
|
73
|
-
|
|
74
|
-
|
|
75
|
-
|
|
76
|
-
|
|
77
|
-
|
|
78
|
-
|
|
79
|
-
|
|
80
|
-
|
|
81
|
-
|
|
82
|
-
|
|
83
|
-
|
|
84
|
-
|
|
85
|
-
|
|
86
|
-
|
|
87
|
-
|
|
88
|
-
}, placeholder: "Enter tag value" })),
|
|
89
|
-
React.createElement(Paper, { className: classes.paper, variant: "outlined" },
|
|
90
|
-
React.createElement(Typography, null, "Filter by read name"),
|
|
91
|
-
React.createElement(TextField, { className: classes.field, value: readName, onChange: event => {
|
|
92
|
-
setReadName(event.target.value);
|
|
93
|
-
}, placeholder: "Enter read name" })),
|
|
94
|
-
React.createElement(DialogActions, null,
|
|
95
|
-
React.createElement(Button, { variant: "contained", color: "primary", autoFocus: true, type: "submit", onClick: () => {
|
|
96
|
-
model.setFilterBy({
|
|
97
|
-
flagInclude,
|
|
98
|
-
flagExclude,
|
|
99
|
-
readName,
|
|
100
|
-
tagFilter: tag !== ''
|
|
101
|
-
? {
|
|
102
|
-
tag,
|
|
103
|
-
value: tagValue,
|
|
104
|
-
}
|
|
105
|
-
: undefined,
|
|
106
|
-
});
|
|
107
|
-
handleClose();
|
|
108
|
-
} }, "Submit"),
|
|
109
|
-
React.createElement(Button, { variant: "contained", color: "secondary", onClick: () => {
|
|
110
|
-
handleClose();
|
|
111
|
-
} }, "Cancel")))));
|
|
59
|
+
return (_jsx(Dialog, { open: true, onClose: handleClose, title: "Filter options", children: _jsxs(DialogContent, { children: [_jsxs(Typography, { children: ["Set filter bitmask options. Refer to ", _jsx(Link, { href: site, children: site }), ' ', "for details"] }), _jsx(Paper, { className: classes.paper, variant: "outlined", children: _jsxs("div", { style: { display: 'flex' }, children: [_jsxs("div", { children: [_jsx(Typography, { children: "Read must have ALL these flags" }), _jsx(Bitmask, { flag: flagInclude, setFlag: setFlagInclude })] }), _jsxs("div", { children: [_jsx(Typography, { children: "Read must have NONE of these flags" }), _jsx(Bitmask, { flag: flagExclude, setFlag: setFlagExclude })] })] }) }), _jsxs(Paper, { className: classes.paper, variant: "outlined", children: [_jsx(Typography, { children: "Filter by tag name and value. Use * in the value field to get all reads containing any value for that tag. Example: filter tag name SA with value * to get all split/supplementary reads. Other examples include HP for haplotype, or RG for read group" }), _jsx(TextField, { className: classes.field, value: tag, onChange: event => {
|
|
60
|
+
setTag(event.target.value);
|
|
61
|
+
}, placeholder: "Enter tag name", error: tag.length === 2 && !validTag, helperText: tag.length === 2 && !validTag ? 'Not a valid tag' : '', slotProps: {
|
|
62
|
+
htmlInput: {
|
|
63
|
+
maxLength: 2,
|
|
64
|
+
},
|
|
65
|
+
} }), _jsx(TextField, { className: classes.field, value: tagValue, onChange: event => {
|
|
66
|
+
setTagValue(event.target.value);
|
|
67
|
+
}, placeholder: "Enter tag value" })] }), _jsxs(Paper, { className: classes.paper, variant: "outlined", children: [_jsx(Typography, { children: "Filter by read name" }), _jsx(TextField, { className: classes.field, value: readName, onChange: event => {
|
|
68
|
+
setReadName(event.target.value);
|
|
69
|
+
}, placeholder: "Enter read name" })] }), _jsxs(DialogActions, { children: [_jsx(Button, { variant: "contained", color: "primary", autoFocus: true, type: "submit", onClick: () => {
|
|
70
|
+
model.setFilterBy({
|
|
71
|
+
flagInclude,
|
|
72
|
+
flagExclude,
|
|
73
|
+
readName,
|
|
74
|
+
tagFilter: tag !== ''
|
|
75
|
+
? {
|
|
76
|
+
tag,
|
|
77
|
+
value: tagValue,
|
|
78
|
+
}
|
|
79
|
+
: undefined,
|
|
80
|
+
});
|
|
81
|
+
handleClose();
|
|
82
|
+
}, children: "Submit" }), _jsx(Button, { variant: "contained", color: "secondary", onClick: () => {
|
|
83
|
+
handleClose();
|
|
84
|
+
}, children: "Cancel" })] })] }) }));
|
|
112
85
|
});
|
|
113
86
|
export default FilterByTagDialog;
|
|
@@ -1,7 +1,6 @@
|
|
|
1
|
-
import React from 'react';
|
|
2
1
|
export declare function renderSvg<T extends {
|
|
3
2
|
id: string;
|
|
4
3
|
height: number;
|
|
5
4
|
}>(self: T, opts: {
|
|
6
5
|
rasterizeLayers?: boolean;
|
|
7
|
-
}, cb: (model: T, ctx: CanvasRenderingContext2D, width: number, height: number) => void): Promise<
|
|
6
|
+
}, cb: (model: T, ctx: CanvasRenderingContext2D, width: number, height: number) => void): Promise<import("react/jsx-runtime").JSX.Element | undefined>;
|
|
@@ -1,4 +1,4 @@
|
|
|
1
|
-
import
|
|
1
|
+
import { jsx as _jsx, Fragment as _Fragment, jsxs as _jsxs } from "react/jsx-runtime";
|
|
2
2
|
import { getContainingView } from '@jbrowse/core/util';
|
|
3
3
|
function getId(id) {
|
|
4
4
|
const isJest = typeof jest === 'undefined';
|
|
@@ -18,17 +18,13 @@ export async function renderSvg(self, opts, cb) {
|
|
|
18
18
|
}
|
|
19
19
|
ctx.scale(2, 2);
|
|
20
20
|
cb(self, ctx, width, height);
|
|
21
|
-
return (
|
|
21
|
+
return (_jsx("image", { width: width, height: height, xlinkHref: canvas.toDataURL('image/png') }));
|
|
22
22
|
}
|
|
23
23
|
else {
|
|
24
24
|
const C2S = await import('canvas2svg');
|
|
25
25
|
const ctx = new C2S.default(width, height);
|
|
26
26
|
cb(self, ctx, width, height);
|
|
27
27
|
const clipid = getId(self.id);
|
|
28
|
-
return (
|
|
29
|
-
React.createElement("defs", null,
|
|
30
|
-
React.createElement("clipPath", { id: clipid },
|
|
31
|
-
React.createElement("rect", { x: 0, y: 0, width: width, height: height }))),
|
|
32
|
-
React.createElement("g", { dangerouslySetInnerHTML: { __html: ctx.getSvg().innerHTML }, clipPath: `url(#${clipid})` })));
|
|
28
|
+
return (_jsxs(_Fragment, { children: [_jsx("defs", { children: _jsx("clipPath", { id: clipid, children: _jsx("rect", { x: 0, y: 0, width: width, height: height }) }) }), _jsx("g", { dangerouslySetInnerHTML: { __html: ctx.getSvg().innerHTML }, clipPath: `url(#${clipid})` })] }));
|
|
33
29
|
}
|
|
34
30
|
}
|
package/package.json
CHANGED
|
@@ -1,6 +1,6 @@
|
|
|
1
1
|
{
|
|
2
2
|
"name": "@jbrowse/plugin-alignments",
|
|
3
|
-
"version": "
|
|
3
|
+
"version": "3.0.1",
|
|
4
4
|
"description": "JBrowse 2 alignments adapters, tracks, etc.",
|
|
5
5
|
"keywords": [
|
|
6
6
|
"jbrowse",
|
|
@@ -36,32 +36,32 @@
|
|
|
36
36
|
"clean": "rimraf dist esm *.tsbuildinfo"
|
|
37
37
|
},
|
|
38
38
|
"dependencies": {
|
|
39
|
-
"@gmod/bam": "^
|
|
40
|
-
"@gmod/cram": "^
|
|
41
|
-
"@jbrowse/
|
|
39
|
+
"@gmod/bam": "^5.0.0",
|
|
40
|
+
"@gmod/cram": "^4.0.1",
|
|
41
|
+
"@jbrowse/core": "^3.0.1",
|
|
42
|
+
"@jbrowse/plugin-linear-genome-view": "^3.0.1",
|
|
43
|
+
"@jbrowse/plugin-wiggle": "^3.0.1",
|
|
44
|
+
"@jbrowse/sv-core": "^3.0.1",
|
|
42
45
|
"@mui/icons-material": "^6.0.0",
|
|
46
|
+
"@mui/material": "^6.0.0",
|
|
43
47
|
"canvas2svg": "^1.0.16",
|
|
44
48
|
"copy-to-clipboard": "^3.3.1",
|
|
45
49
|
"fast-deep-equal": "^3.1.3",
|
|
46
|
-
"generic-
|
|
47
|
-
},
|
|
48
|
-
"peerDependencies": {
|
|
49
|
-
"@jbrowse/core": "^2.0.0",
|
|
50
|
-
"@jbrowse/plugin-linear-genome-view": "^2.0.0",
|
|
51
|
-
"@jbrowse/plugin-wiggle": "^2.0.0",
|
|
52
|
-
"@mui/material": "^6.0.0",
|
|
50
|
+
"generic-filehandle2": "^1.0.0",
|
|
53
51
|
"mobx": "^6.0.0",
|
|
54
52
|
"mobx-react": "^9.0.0",
|
|
55
53
|
"mobx-state-tree": "^5.0.0",
|
|
56
|
-
"react": ">=16.8.0",
|
|
57
54
|
"rxjs": "^7.0.0",
|
|
58
55
|
"tss-react": "^4.0.0"
|
|
59
56
|
},
|
|
57
|
+
"peerDependencies": {
|
|
58
|
+
"react": ">=18.0.0"
|
|
59
|
+
},
|
|
60
60
|
"publishConfig": {
|
|
61
61
|
"access": "public"
|
|
62
62
|
},
|
|
63
63
|
"distModule": "esm/index.js",
|
|
64
64
|
"srcModule": "src/index.ts",
|
|
65
65
|
"module": "esm/index.js",
|
|
66
|
-
"gitHead": "
|
|
66
|
+
"gitHead": "aa2f1d1a89d2361c7fd1a93fe29506fa4554f5cc"
|
|
67
67
|
}
|