@inflexa-ai/harness 0.45.1 → 0.46.0
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/README.md +6 -3
- package/dist/agents/conversation-agent.d.ts +9 -3
- package/dist/agents/conversation-agent.js +34 -33
- package/dist/agents/report-session-agent.d.ts +15 -15
- package/dist/agents/report-session-agent.js +23 -15
- package/dist/agents/sandbox/index.d.ts +1 -1
- package/dist/agents/sandbox/index.js +1 -1
- package/dist/agents/sandbox/shared.d.ts +12 -14
- package/dist/agents/sandbox/shared.js +18 -12
- package/dist/agents/sandbox/types.d.ts +4 -4
- package/dist/agents/sandbox/validate-skills.d.ts +2 -2
- package/dist/agents/sandbox/validate-skills.js +3 -1
- package/dist/agents/sandbox-catalog.d.ts +2 -2
- package/dist/agents/sandbox-catalog.js +3 -3
- package/dist/agents/system-prompt.d.ts +2 -2
- package/dist/app/chat-turn-workflow.d.ts +114 -0
- package/dist/app/chat-turn-workflow.js +307 -0
- package/dist/app/chat-turn.d.ts +85 -57
- package/dist/app/chat-turn.js +123 -100
- package/dist/app/data-profile-orientation.js +10 -8
- package/dist/app/data-profile-view.d.ts +4 -4
- package/dist/app/data-profile-view.js +9 -8
- package/dist/app/in-process-turn.d.ts +42 -0
- package/dist/app/in-process-turn.js +139 -0
- package/dist/app/message-assembly.d.ts +10 -4
- package/dist/app/message-assembly.js +13 -8
- package/dist/app/report-session-runtime.d.ts +4 -4
- package/dist/app/report-session-runtime.js +36 -21
- package/dist/app/spawn-report-session.d.ts +33 -28
- package/dist/app/spawn-report-session.js +25 -40
- package/dist/app/synthesize-run.d.ts +22 -16
- package/dist/app/synthesize-run.js +41 -35
- package/dist/app/work.d.ts +96 -0
- package/dist/app/work.js +147 -0
- package/dist/auth/local-auth-context.d.ts +1 -3
- package/dist/auth/local-auth-context.js +1 -3
- package/dist/auth/local-run-authorizer.d.ts +1 -1
- package/dist/auth/local-run-authorizer.js +5 -3
- package/dist/auth/types.d.ts +26 -26
- package/dist/billing/cached-resolver.d.ts +4 -4
- package/dist/billing/run-charge.d.ts +5 -8
- package/dist/billing/run-charge.js +2 -2
- package/dist/billing/usage-recorder.d.ts +9 -9
- package/dist/citations/aggregate.js +1 -1
- package/dist/citations/clients/arxiv.d.ts +2 -2
- package/dist/citations/clients/arxiv.js +12 -4
- package/dist/citations/clients/common.js +4 -2
- package/dist/citations/clients/crossref.d.ts +2 -2
- package/dist/citations/clients/crossref.js +37 -37
- package/dist/citations/clients/doi-registry.js +15 -16
- package/dist/citations/clients/pubmed.d.ts +2 -2
- package/dist/citations/clients/pubmed.js +20 -13
- package/dist/citations/clients/semantic-scholar.d.ts +2 -2
- package/dist/citations/clients/semantic-scholar.js +9 -9
- package/dist/citations/compare.js +2 -2
- package/dist/citations/match.d.ts +2 -2
- package/dist/citations/match.js +12 -7
- package/dist/citations/normalize.js +35 -26
- package/dist/citations/plan.js +6 -2
- package/dist/citations/resolve.d.ts +6 -6
- package/dist/citations/resolve.js +34 -25
- package/dist/citations/types.d.ts +77 -77
- package/dist/config/environment-stores.d.ts +6 -6
- package/dist/config/resource-limits.js +1 -3
- package/dist/contracts/analogy-report.d.ts +7 -7
- package/dist/contracts/analogy-report.js +2 -2
- package/dist/contracts/chat-events.d.ts +38 -24
- package/dist/contracts/chat-frame.d.ts +15 -5
- package/dist/contracts/chat-frame.js +64 -41
- package/dist/contracts/chat-parts.d.ts +130 -67
- package/dist/contracts/chat-parts.js +1 -0
- package/dist/contracts/content-url.js +16 -2
- package/dist/contracts/data-profile.d.ts +38 -38
- package/dist/contracts/index.d.ts +2 -2
- package/dist/contracts/index.js +1 -1
- package/dist/contracts/message.d.ts +6 -6
- package/dist/contracts/organ-system.d.ts +11 -11
- package/dist/contracts/part-registry.d.ts +5 -4
- package/dist/contracts/part-registry.js +5 -0
- package/dist/contracts/profile-vocabulary.d.ts +11 -10
- package/dist/contracts/profile-vocabulary.js +10 -3
- package/dist/contracts/report-blocks.d.ts +329 -329
- package/dist/contracts/report-reference.d.ts +105 -81
- package/dist/contracts/report-reference.js +30 -13
- package/dist/contracts/schemas/chat-events.d.ts +30 -16
- package/dist/contracts/schemas/chat-events.js +15 -6
- package/dist/contracts/schemas/chat-parts.d.ts +175 -102
- package/dist/contracts/schemas/chat-parts.js +33 -7
- package/dist/contracts/severity.d.ts +1 -1
- package/dist/contracts/structure-source.d.ts +3 -3
- package/dist/contracts/structure-source.js +6 -2
- package/dist/contracts/subagent-activity.d.ts +2 -2
- package/dist/contracts/subagent-activity.js +5 -3
- package/dist/contracts/usage.d.ts +2 -2
- package/dist/data/safety-panel-schema.d.ts +25 -25
- package/dist/data/safety-panel-schema.js +13 -4
- package/dist/execution/artifact-metadata.d.ts +23 -15
- package/dist/execution/artifact-metadata.js +33 -10
- package/dist/execution/artifact-record.d.ts +2 -2
- package/dist/execution/artifact-registration.d.ts +5 -5
- package/dist/execution/artifact-registry.d.ts +8 -8
- package/dist/execution/dbos-run-launcher.d.ts +24 -4
- package/dist/execution/dbos-run-launcher.js +58 -4
- package/dist/execution/dbos-workflow-purger.d.ts +5 -6
- package/dist/execution/dbos-workflow-purger.js +8 -7
- package/dist/execution/input-signature.d.ts +2 -2
- package/dist/execution/post-step-pipeline.d.ts +9 -9
- package/dist/execution/post-step-pipeline.js +1 -1
- package/dist/execution/post-step.js +2 -2
- package/dist/execution/reconcile-manifest.d.ts +4 -4
- package/dist/execution/reconcile-manifest.js +3 -2
- package/dist/execution/run-authorizer.d.ts +46 -37
- package/dist/execution/run-authorizer.js +8 -8
- package/dist/execution/run-canceler.d.ts +7 -7
- package/dist/execution/run-canceler.js +14 -7
- package/dist/execution/run-end-record.d.ts +2 -3
- package/dist/execution/run-event-parts.d.ts +0 -8
- package/dist/execution/run-event-parts.js +29 -24
- package/dist/execution/run-event-stream.d.ts +8 -8
- package/dist/execution/run-event-stream.js +3 -4
- package/dist/execution/run-launcher.d.ts +4 -4
- package/dist/execution/run-synthesis.d.ts +49 -48
- package/dist/execution/run-synthesis.js +96 -255
- package/dist/execution/staged-input.d.ts +2 -2
- package/dist/execution/step-summary.d.ts +6 -6
- package/dist/execution/step-summary.js +4 -8
- package/dist/execution/topo-sort.js +4 -3
- package/dist/execution/workflow-purger.d.ts +2 -2
- package/dist/index.d.ts +17 -20
- package/dist/index.js +25 -36
- package/dist/input-sanitization.js +9 -2
- package/dist/input-scan/clustering.d.ts +6 -6
- package/dist/input-scan/clustering.js +11 -5
- package/dist/input-scan/companions.js +3 -2
- package/dist/input-scan/detect-sets.d.ts +2 -2
- package/dist/input-scan/detect-sets.js +25 -21
- package/dist/input-scan/enrich.d.ts +6 -6
- package/dist/input-scan/enrich.js +29 -12
- package/dist/input-scan/formats.d.ts +2 -2
- package/dist/input-scan/formats.js +8 -2
- package/dist/input-scan/markers.d.ts +2 -2
- package/dist/input-scan/markers.js +14 -5
- package/dist/input-scan/menu.d.ts +10 -10
- package/dist/input-scan/menu.js +0 -0
- package/dist/input-scan/quarantine.d.ts +2 -2
- package/dist/input-scan/quarantine.js +23 -18
- package/dist/input-scan/readout-budget.d.ts +2 -2
- package/dist/input-scan/readout-budget.js +1 -1
- package/dist/input-scan/readout.d.ts +2 -2
- package/dist/input-scan/readout.js +47 -34
- package/dist/input-scan/scan.d.ts +2 -2
- package/dist/input-scan/scan.js +7 -5
- package/dist/input-scan/set-types.d.ts +28 -28
- package/dist/input-scan/shapes.d.ts +4 -4
- package/dist/input-scan/shapes.js +0 -0
- package/dist/input-scan/templates.d.ts +10 -10
- package/dist/input-scan/templates.js +30 -22
- package/dist/input-scan/tokens.d.ts +6 -4
- package/dist/input-scan/tokens.js +100 -38
- package/dist/input-scan/types.d.ts +22 -22
- package/dist/lib/async-utils.d.ts +3 -7
- package/dist/lib/async-utils.js +5 -9
- package/dist/lib/cache.js +1 -1
- package/dist/lib/chrome.d.ts +46 -6
- package/dist/lib/console-logger.js +2 -2
- package/dist/lib/db-result.d.ts +22 -6
- package/dist/lib/db-result.js +9 -13
- package/dist/lib/eyes.d.ts +4 -4
- package/dist/lib/eyes.js +1 -1
- package/dist/lib/fs-helpers.js +18 -6
- package/dist/lib/fs-result.d.ts +1 -0
- package/dist/lib/fs-result.js +5 -6
- package/dist/lib/hooks.d.ts +23 -7
- package/dist/lib/hooks.js +17 -3
- package/dist/lib/host-concurrency.js +3 -2
- package/dist/lib/logger.d.ts +2 -2
- package/dist/lib/logger.js +2 -1
- package/dist/lib/metrics.d.ts +1 -1
- package/dist/lib/null-proto.d.ts +6 -0
- package/dist/lib/null-proto.js +17 -0
- package/dist/lib/otel-spans.d.ts +1 -1
- package/dist/lib/otel-spans.js +9 -5
- package/dist/lib/otel.d.ts +4 -2
- package/dist/lib/otel.js +10 -2
- package/dist/lib/page-capture.d.ts +8 -8
- package/dist/lib/page-capture.js +9 -4
- package/dist/lib/parse-json.d.ts +5 -0
- package/dist/lib/parse-json.js +12 -0
- package/dist/lib/present.d.ts +12 -0
- package/dist/lib/present.js +39 -0
- package/dist/lib/rate-limit.d.ts +4 -4
- package/dist/lib/rate-limit.js +12 -13
- package/dist/lib/regulatory-corpus/fetch-fda-guidance.d.ts +4 -4
- package/dist/lib/regulatory-corpus/fetch-fda-guidance.js +4 -10
- package/dist/lib/regulatory-corpus/fetch-ich.d.ts +4 -4
- package/dist/lib/regulatory-corpus/fetch-ich.js +18 -14
- package/dist/lib/regulatory-corpus/normalize-whitespace.d.ts +6 -0
- package/dist/lib/regulatory-corpus/normalize-whitespace.js +41 -0
- package/dist/lib/regulatory-corpus.d.ts +10 -10
- package/dist/lib/regulatory-corpus.js +3 -1
- package/dist/lib/result.d.ts +10 -11
- package/dist/lib/result.js +15 -13
- package/dist/lib/storage.d.ts +2 -2
- package/dist/lib/test/async-iterable.d.ts +9 -0
- package/dist/lib/test/async-iterable.js +28 -0
- package/dist/lib/test/request-url.d.ts +5 -0
- package/dist/lib/test/request-url.js +7 -0
- package/dist/lib/test/result-assert.d.ts +12 -0
- package/dist/lib/test/result-assert.js +17 -0
- package/dist/lib/test/text-shapes.d.ts +24 -0
- package/dist/lib/test/text-shapes.js +63 -0
- package/dist/lib/text.d.ts +22 -0
- package/dist/lib/text.js +68 -0
- package/dist/lib/thrown.d.ts +18 -0
- package/dist/lib/thrown.js +30 -0
- package/dist/lib/unknown-array.d.ts +6 -0
- package/dist/lib/unknown-array.js +8 -0
- package/dist/lib/unknown-containers.d.ts +14 -0
- package/dist/lib/unknown-containers.js +17 -0
- package/dist/lib/unknown-text.d.ts +8 -0
- package/dist/lib/unknown-text.js +28 -0
- package/dist/lib/zod-issue-shape.d.ts +1 -1
- package/dist/lib/zod-issue-shape.js +31 -31
- package/dist/lib/zod-issues.d.ts +3 -3
- package/dist/lib/zod-issues.js +30 -17
- package/dist/literature/sources/arxiv.d.ts +6 -6
- package/dist/literature/sources/arxiv.js +92 -35
- package/dist/literature/sources/http.d.ts +2 -2
- package/dist/literature/sources/http.js +16 -15
- package/dist/literature/sources/pubmed.d.ts +16 -16
- package/dist/literature/sources/pubmed.js +96 -61
- package/dist/literature/sources/semantic-scholar.d.ts +8 -8
- package/dist/literature/sources/semantic-scholar.js +22 -13
- package/dist/loop/accounting.d.ts +63 -0
- package/dist/loop/accounting.js +141 -0
- package/dist/loop/call-policy.d.ts +73 -0
- package/dist/loop/call-policy.js +109 -0
- package/dist/loop/chat-stream.d.ts +62 -0
- package/dist/loop/chat-stream.js +237 -0
- package/dist/loop/compaction.d.ts +9 -9
- package/dist/loop/compaction.js +1 -1
- package/dist/loop/metrics.d.ts +12 -15
- package/dist/loop/metrics.js +14 -26
- package/dist/loop/run-loop.d.ts +233 -0
- package/dist/loop/run-loop.js +770 -0
- package/dist/loop/sub-agent.d.ts +61 -0
- package/dist/loop/sub-agent.js +161 -0
- package/dist/loop/tool-adapter.d.ts +98 -0
- package/dist/loop/tool-adapter.js +364 -0
- package/dist/loop/tool-detail.d.ts +1 -1
- package/dist/loop/tool-detail.js +6 -5
- package/dist/loop/tool-outcome.d.ts +1 -1
- package/dist/loop/tool-output.d.ts +4 -4
- package/dist/loop/tool-output.js +2 -2
- package/dist/loop/turn-credentials.d.ts +34 -0
- package/dist/loop/turn-credentials.js +73 -0
- package/dist/loop/types.d.ts +29 -38
- package/dist/loop/types.js +2 -7
- package/dist/memory/ai-sdk-message-storage.d.ts +5 -5
- package/dist/memory/ai-sdk-message-storage.js +13 -11
- package/dist/memory/card-builders.d.ts +14 -14
- package/dist/memory/card-builders.js +19 -15
- package/dist/memory/conversation-display-recorder.d.ts +22 -4
- package/dist/memory/conversation-display-recorder.js +43 -24
- package/dist/memory/conversation-display-replay.js +3 -2
- package/dist/memory/conversation-display-storage.d.ts +15 -7
- package/dist/memory/conversation-display-storage.js +141 -36
- package/dist/memory/conversation-view.d.ts +4 -4
- package/dist/memory/conversation-view.js +5 -4
- package/dist/memory/count-tokens.js +10 -8
- package/dist/memory/derive-thread-title.d.ts +0 -13
- package/dist/memory/derive-thread-title.js +2 -1
- package/dist/memory/message-backfill.d.ts +12 -5
- package/dist/memory/message-backfill.js +5 -3
- package/dist/memory/thread-history.d.ts +36 -21
- package/dist/memory/thread-history.js +78 -54
- package/dist/memory/thread-store.d.ts +26 -17
- package/dist/memory/thread-store.js +15 -9
- package/dist/memory/tool-call-integrity.d.ts +2 -2
- package/dist/memory/tool-call-integrity.js +4 -3
- package/dist/memory/working-memory.d.ts +16 -12
- package/dist/memory/working-memory.js +72 -61
- package/dist/prompts/briefing.d.ts +12 -12
- package/dist/prompts/briefing.js +1 -1
- package/dist/prompts/synthesis-agent.d.ts +1 -1
- package/dist/prompts/synthesis-agent.js +6 -14
- package/dist/provenance/collector.d.ts +6 -6
- package/dist/provenance/collector.js +15 -8
- package/dist/provenance/exec-frame.d.ts +2 -2
- package/dist/provenance/exec-frame.js +6 -1
- package/dist/provenance/seam.d.ts +1 -4
- package/dist/provenance/types.d.ts +6 -6
- package/dist/providers/ai-sdk.d.ts +113 -62
- package/dist/providers/ai-sdk.js +283 -518
- package/dist/providers/embedding.d.ts +2 -2
- package/dist/providers/embedding.js +1 -1
- package/dist/providers/errors.d.ts +22 -2
- package/dist/providers/errors.js +98 -50
- package/dist/providers/prompt-cache.d.ts +8 -8
- package/dist/providers/prompt-cache.js +13 -11
- package/dist/providers/reasoning.d.ts +2 -2
- package/dist/providers/reasoning.js +2 -2
- package/dist/providers/types.d.ts +55 -94
- package/dist/reference-data/catalog.d.ts +2 -15
- package/dist/reference-data/catalog.js +25 -8
- package/dist/reference-data/receipt.d.ts +2 -2
- package/dist/report-model/assert-rules.js +1 -1
- package/dist/report-model/authoring-grammar.d.ts +211 -233
- package/dist/report-model/block-walk.d.ts +10 -10
- package/dist/report-model/block-walk.js +2 -0
- package/dist/report-model/draft-finish.d.ts +8 -8
- package/dist/report-model/draft-finish.js +1 -1
- package/dist/report-model/draft-hash.js +8 -7
- package/dist/report-model/draft-operations.d.ts +22 -10
- package/dist/report-model/draft-operations.js +48 -30
- package/dist/report-model/draft-read.d.ts +19 -7
- package/dist/report-model/draft-read.js +16 -6
- package/dist/report-model/draft.d.ts +844 -2
- package/dist/report-model/draft.js +3 -1
- package/dist/report-model/fixture-resolver.js +39 -16
- package/dist/report-model/pin-snapshot.d.ts +2 -2
- package/dist/report-model/pin-snapshot.js +15 -15
- package/dist/report-model/production-resolver.d.ts +18 -18
- package/dist/report-model/production-resolver.js +50 -42
- package/dist/report-model/reference-resolver.d.ts +26 -10
- package/dist/report-model/reference-resolver.js +68 -5
- package/dist/report-model/reference-stamp.js +30 -38
- package/dist/report-model/structural-validation.js +12 -4
- package/dist/report-model/validate.d.ts +7 -7
- package/dist/report-model/validate.js +6 -6
- package/dist/report-render/assets.d.ts +2 -2
- package/dist/report-render/assets.js +27 -3
- package/dist/report-render/chart-export.d.ts +10 -2
- package/dist/report-render/chart-export.js +37 -11
- package/dist/report-render/chart-presets.d.ts +8 -8
- package/dist/report-render/chart-presets.js +3 -3
- package/dist/report-render/chart-renderers.d.ts +23 -16
- package/dist/report-render/chart-renderers.js +74 -53
- package/dist/report-render/chart-toolbox.d.ts +2 -2
- package/dist/report-render/chart-toolbox.js +7 -6
- package/dist/report-render/chart.d.ts +15 -16
- package/dist/report-render/chart.js +369 -252
- package/dist/report-render/design.d.ts +36 -297
- package/dist/report-render/design.js +0 -12
- package/dist/report-render/figures/common.d.ts +12 -12
- package/dist/report-render/figures/common.js +42 -31
- package/dist/report-render/figures/dendrogram.d.ts +3 -3
- package/dist/report-render/figures/dendrogram.js +10 -10
- package/dist/report-render/figures/dense.js +15 -8
- package/dist/report-render/figures/dotplot.js +46 -33
- package/dist/report-render/figures/embedding.js +52 -43
- package/dist/report-render/figures/equal-units.d.ts +10 -10
- package/dist/report-render/figures/equal-units.js +27 -27
- package/dist/report-render/figures/forest.js +9 -7
- package/dist/report-render/figures/gsea.js +21 -11
- package/dist/report-render/figures/heatmap.js +13 -9
- package/dist/report-render/figures/index.d.ts +10 -10
- package/dist/report-render/figures/index.js +4 -2
- package/dist/report-render/figures/km.js +10 -9
- package/dist/report-render/figures/label-room.d.ts +12 -12
- package/dist/report-render/figures/label-room.js +7 -2
- package/dist/report-render/figures/locuszoom.d.ts +2 -2
- package/dist/report-render/figures/locuszoom.js +59 -31
- package/dist/report-render/figures/lollipop.js +3 -2
- package/dist/report-render/figures/ma.js +8 -4
- package/dist/report-render/figures/manhattan.d.ts +1 -2
- package/dist/report-render/figures/manhattan.js +52 -34
- package/dist/report-render/figures/oncoprint.js +4 -5
- package/dist/report-render/figures/pca.js +25 -11
- package/dist/report-render/figures/qq.js +20 -9
- package/dist/report-render/figures/roc.js +1 -1
- package/dist/report-render/figures/sankey.d.ts +2 -2
- package/dist/report-render/figures/sankey.js +11 -10
- package/dist/report-render/figures/upset.d.ts +6 -6
- package/dist/report-render/figures/upset.js +7 -4
- package/dist/report-render/figures/volcano.js +12 -10
- package/dist/report-render/hybrid-svg.d.ts +4 -4
- package/dist/report-render/hybrid-svg.js +7 -5
- package/dist/report-render/number-format.d.ts +4 -4
- package/dist/report-render/number-format.js +62 -27
- package/dist/report-render/page.js +2 -1
- package/dist/report-render/provenance-data.d.ts +2 -2
- package/dist/report-render/references.d.ts +4 -4
- package/dist/report-render/render.d.ts +2 -2
- package/dist/report-render/render.js +10 -11
- package/dist/report-render/script-json.js +1 -1
- package/dist/report-render/table-data.d.ts +6 -6
- package/dist/report-render/test/options.d.ts +49 -0
- package/dist/report-render/test/options.js +143 -0
- package/dist/report-render/test/page-function.d.ts +19 -0
- package/dist/report-render/test/page-function.js +33 -0
- package/dist/report-render/types.d.ts +10 -10
- package/dist/report-render/value-bridge.d.ts +4 -4
- package/dist/report-render/value-bridge.js +27 -14
- package/dist/report-render/views/chart-view.d.ts +2 -2
- package/dist/report-render/views/chart-view.js +2 -2
- package/dist/report-render/views/lineage.d.ts +6 -6
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- package/dist/loop/continue-agent.d.ts +0 -40
- package/dist/loop/continue-agent.js +0 -38
- package/dist/loop/genai-spans.d.ts +0 -47
- package/dist/loop/genai-spans.js +0 -134
- package/dist/loop/run-agent.d.ts +0 -245
- package/dist/loop/run-agent.js +0 -1124
- package/dist/loop/run-step.d.ts +0 -29
- package/dist/loop/run-step.js +0 -34
- package/dist/loop/run-to-terminal.d.ts +0 -66
- package/dist/loop/run-to-terminal.js +0 -93
- package/dist/loop/tool-mask.d.ts +0 -23
- package/dist/loop/tool-mask.js +0 -46
- package/dist/providers/streaming-chat.d.ts +0 -32
- package/dist/providers/streaming-chat.js +0 -91
- package/dist/tasks/derive-table-exec.d.ts +0 -54
- package/dist/tasks/derive-table-exec.js +0 -86
- package/dist/workflows/suspension.d.ts +0 -32
- package/dist/workflows/suspension.js +0 -38
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query: z.ZodOptional<z.ZodString>;
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inventor: z.ZodOptional<z.ZodString>;
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cpcCodes: z.ZodOptional<z.ZodArray<z.ZodString>>;
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applicationNumber: z.ZodOptional<z.ZodString>;
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includeDescription: z.ZodDefault<z.ZodBoolean>;
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import { describeAmassError, getPatentRecord, lookupPatentIds, searchPatentRecords, } from "../lib/amass-client.js";
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/** The largest `limit` that still costs one search price (5 credits for each 20 records). */
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const ISO_DATE = /^\d{4}-\d{2}-\d{2}$/;
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throw new Error("search requires query");
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return ok({ status: "ambiguous", candidates: ids.value });
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* and its accession is the key that the structural tools take.
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import { type UniProtProtein } from "../lib/uniprot-client.js";
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export
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export type SearchProteinOutput = {
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readonly proteins: UniProtProtein[];
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/** True when UniProt held at least one row beyond `limit`. */
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};
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export declare const searchProteinTool: import("../define-tool.js").Tool<{
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query: string;
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describeCall: ({ query }) => query,
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organismId: organismId ?? undefined,
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reviewedOnly,
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limit,
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* `z.discriminatedUnion`, which `defineTool` rejects (model tool calling needs a
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import { type AuthorizationRecord, type AuthorizationSearchRow, type RegulatorySection } from "../lib/amass-client.js";
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declare const inputSchema: z.ZodObject<{
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action: z.ZodDefault<z.ZodEnum<{
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details: "details";
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search: "search";
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section: "section";
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}>>;
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query: z.ZodOptional<z.ZodString>;
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agency: z.ZodOptional<z.ZodArray<z.ZodEnum<{
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EMA: "EMA";
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FDA: "FDA";
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}>>>;
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authorizationStatus: z.ZodOptional<z.ZodArray<z.ZodEnum<{
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ACTIVE: "ACTIVE";
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APPROVED_NOT_MARKETED: "APPROVED_NOT_MARKETED";
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CONDITIONAL: "CONDITIONAL";
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EXPIRED: "EXPIRED";
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LAPSED_SUNSET: "LAPSED_SUNSET";
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REFUSED: "REFUSED";
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REVOKED: "REVOKED";
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SUSPENDED: "SUSPENDED";
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UNKNOWN: "UNKNOWN";
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WITHDRAWN_DURING_REVIEW: "WITHDRAWN_DURING_REVIEW";
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WITHDRAWN_FORCED: "WITHDRAWN_FORCED";
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WITHDRAWN_VOLUNTARY: "WITHDRAWN_VOLUNTARY";
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}>>>;
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moleculeType: z.ZodOptional<z.ZodArray<z.ZodEnum<{
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ANTIBODY: "ANTIBODY";
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ANTIBODY_DRUG_CONJUGATE: "ANTIBODY_DRUG_CONJUGATE";
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CELL: "CELL";
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ENZYME: "ENZYME";
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GENE: "GENE";
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OLIGONUCLEOTIDE: "OLIGONUCLEOTIDE";
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OLIGOSACCHARIDE: "OLIGOSACCHARIDE";
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PROTEIN: "PROTEIN";
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SMALL_MOLECULE: "SMALL_MOLECULE";
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UNKNOWN: "UNKNOWN";
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VACCINE: "VACCINE";
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VACCINE_COMPONENT: "VACCINE_COMPONENT";
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}>>>;
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hasDesignation: z.ZodOptional<z.ZodArray<z.ZodEnum<{
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ACCELERATED_APPROVAL: "ACCELERATED_APPROVAL";
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ACCELERATED_ASSESSMENT: "ACCELERATED_ASSESSMENT";
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BREAKTHROUGH_THERAPY: "BREAKTHROUGH_THERAPY";
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CONDITIONAL_MA: "CONDITIONAL_MA";
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EXCEPTIONAL_CIRCUMSTANCES: "EXCEPTIONAL_CIRCUMSTANCES";
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FAST_TRACK: "FAST_TRACK";
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PRIME: "PRIME";
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PRIORITY_REVIEW: "PRIORITY_REVIEW";
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RMAT: "RMAT";
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}>>>;
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isOrphan: z.ZodOptional<z.ZodBoolean>;
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minAuthorizationDate: z.ZodOptional<z.ZodString>;
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maxAuthorizationDate: z.ZodOptional<z.ZodString>;
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limit: z.ZodDefault<z.ZodNumber>;
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amassId: z.ZodOptional<z.ZodString>;
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fdaApplicationNumber: z.ZodOptional<z.ZodString>;
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emaProductNumber: z.ZodOptional<z.ZodString>;
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ndc: z.ZodOptional<z.ZodString>;
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splSetId: z.ZodOptional<z.ZodString>;
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documentSectionId: z.ZodOptional<z.ZodString>;
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}, z.core.$strip>;
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type RegulatoryApprovalsOutput = {
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authorizations: AuthorizationSearchRow[];
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} | {
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@@ -28,22 +91,5 @@ type RegulatoryApprovalsOutput = {
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export declare function createSearchRegulatoryApprovalsTool(deps: {
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apiKey: string;
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}):
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action: "search" | "details" | "section";
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limit: number;
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query?: string | undefined;
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agency?: ("FDA" | "EMA")[] | undefined;
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authorizationStatus?: ("UNKNOWN" | "ACTIVE" | "APPROVED_NOT_MARKETED" | "CONDITIONAL" | "SUSPENDED" | "WITHDRAWN_VOLUNTARY" | "WITHDRAWN_FORCED" | "REVOKED" | "LAPSED_SUNSET" | "REFUSED" | "WITHDRAWN_DURING_REVIEW" | "EXPIRED")[] | undefined;
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moleculeType?: ("UNKNOWN" | "SMALL_MOLECULE" | "ANTIBODY" | "PROTEIN" | "ENZYME" | "OLIGONUCLEOTIDE" | "GENE" | "CELL" | "ANTIBODY_DRUG_CONJUGATE" | "VACCINE_COMPONENT" | "VACCINE" | "OLIGOSACCHARIDE")[] | undefined;
|
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hasDesignation?: ("PRIORITY_REVIEW" | "BREAKTHROUGH_THERAPY" | "FAST_TRACK" | "RMAT" | "ACCELERATED_APPROVAL" | "ACCELERATED_ASSESSMENT" | "PRIME" | "CONDITIONAL_MA" | "EXCEPTIONAL_CIRCUMSTANCES")[] | undefined;
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isOrphan?: boolean | undefined;
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minAuthorizationDate?: string | undefined;
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maxAuthorizationDate?: string | undefined;
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amassId?: string | undefined;
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fdaApplicationNumber?: string | undefined;
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emaProductNumber?: string | undefined;
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ndc?: string | undefined;
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splSetId?: string | undefined;
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documentSectionId?: string | undefined;
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}, RegulatoryApprovalsOutput>;
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94
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}): Tool<z.infer<typeof inputSchema>, RegulatoryApprovalsOutput>;
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95
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export {};
|
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@@ -12,13 +12,14 @@
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12
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* top-level `"type":"object"`).
|
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*/
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14
|
import { err, ok } from "neverthrow";
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import { presentFirst } from "../../lib/present.js";
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import { z } from "zod";
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import { defineTool } from "../define-tool.js";
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import { describeAmassError, getRegulatoryRecord, getRegulatorySection, lookupRegulatoryIds, MAX_MATCHED_SECTIONS, REGULATORY_AGENCIES, REGULATORY_AUTHORIZATION_STATUSES, REGULATORY_DESIGNATIONS, REGULATORY_MOLECULE_TYPES, searchRegulatoryRecords, } from "../lib/amass-client.js";
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19
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20
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import { ISO_DATE_PATTERN } from "../../lib/text.js";
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21
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/** The largest `limit` that still costs one search price (5 credits for each 20 records). */
|
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20
22
|
const MAX_LIMIT = 20;
|
|
21
|
-
const ISO_DATE = /^\d{4}-\d{2}-\d{2}$/;
|
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22
23
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const IDENTIFIER_FIELDS = ["amassId", "fdaApplicationNumber", "emaProductNumber", "ndc", "splSetId"];
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.object({
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.optional()
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.describe("'search' only. Keep the authorizations that carry any of these designations."),
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isOrphan: z.boolean().optional().describe("'search' only. true keeps the FDA Orphan Drug / EMA Orphan Medicine authorizations; false drops them."),
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minAuthorizationDate: z.string().regex(
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maxAuthorizationDate: z.string().regex(
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minAuthorizationDate: z.string().regex(ISO_DATE_PATTERN).optional().describe("'search' only. Earliest authorization date, YYYY-MM-DD."),
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maxAuthorizationDate: z.string().regex(ISO_DATE_PATTERN).optional().describe("'search' only. Latest authorization date, YYYY-MM-DD."),
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limit: z
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.number()
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.int()
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execute: async (input) => {
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const headers = getAmassHeaders(deps.apiKey);
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if (input.action === "search") {
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if (input.query === undefined)
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throw new Error("search requires query");
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query: input.query,
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limit: input.limit,
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agency: input.agency ? input.agency : undefined,
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authorizationStatus: input.authorizationStatus ? input.authorizationStatus : undefined,
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moleculeType: input.moleculeType ? input.moleculeType : undefined,
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hasDesignation: input.hasDesignation ? input.hasDesignation : undefined,
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isOrphan: input.isOrphan,
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minAuthorizationDate: input.minAuthorizationDate,
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maxAuthorizationDate: input.maxAuthorizationDate,
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amassId: input.amassId ? input.amassId : undefined,
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}, headers);
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if (rows.isErr())
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return failure(rows.error);
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return ok({ authorizations: rows.value });
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}
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if (input.amassId === undefined || input.documentSectionId === undefined)
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throw new Error("section requires amassId and documentSectionId");
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return failure(section.error);
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let amassId = input.amassId;
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const ids = await lookupRegulatoryIds({
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fdaApplicationNumber: input.fdaApplicationNumber,
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emaProductNumber: input.emaProductNumber,
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ndc: input.ndc,
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splSetId: input.splSetId,
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}, headers);
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if (ids.isErr())
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return failure(ids.error);
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@@ -147,7 +152,7 @@ export function createSearchRegulatoryApprovalsTool(deps) {
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return ok({ status: "not_found" });
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if (ids.value.length > 1)
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return ok({ status: "ambiguous", candidates: ids.value });
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-
amassId = ids.value
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+
amassId = presentFirst(ids.value, "the single regulatory id");
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}
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const record = await getRegulatoryRecord(amassId, headers);
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if (record.isErr())
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@@ -16,7 +16,7 @@ import { type SafetyLiability } from "../lib/opentargets-client.js";
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declare const SOURCES: readonly ["panel", "opentargets"];
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type Source = (typeof SOURCES)[number];
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type ConcreteType = "chembl_id" | "gene_symbol" | "uniprot" | "ensembl_id";
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-
|
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+
type TargetRow = {
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input: string;
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identifierType: ConcreteType;
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22
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/** The Ensembl id Open Targets was queried with, when one could be obtained. */
|
|
@@ -27,27 +27,27 @@ interface TargetRow {
|
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27
27
|
liabilityCount?: number;
|
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28
28
|
/** Why the Open Targets half is absent for this identifier, when it is. */
|
|
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29
|
opentargetsNote?: string;
|
|
30
|
-
}
|
|
31
|
-
|
|
30
|
+
};
|
|
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|
+
type SourceOutcome = {
|
|
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|
source: Source;
|
|
33
33
|
status: "ok" | "no_data" | "unavailable";
|
|
34
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|
/** Identifiers this source returned something for. */
|
|
35
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|
matched: number;
|
|
36
36
|
detail?: string;
|
|
37
|
-
}
|
|
37
|
+
};
|
|
38
38
|
export declare const targetSafetyTool: import("../define-tool.js").Tool<{
|
|
39
39
|
identifiers: string[];
|
|
40
|
-
identifierType?: "auto" | "
|
|
40
|
+
identifierType?: "auto" | "chembl_id" | "ensembl_id" | "gene_symbol" | "uniprot" | undefined;
|
|
41
41
|
sources?: ("opentargets" | "panel")[] | undefined;
|
|
42
|
-
filterOrgan?: "
|
|
43
|
-
minSeverity?: "
|
|
42
|
+
filterOrgan?: "cardiac" | "cns" | "dermatologic" | "endocrine_thyroid" | "gi" | "hematologic" | "hepatic" | "immune" | "metabolic" | "musculoskeletal" | "ocular" | "oncology" | "pancreas" | "pns" | "renal" | "reproductive" | "respiratory" | "vascular" | undefined;
|
|
43
|
+
minSeverity?: "high" | "low" | "medium" | undefined;
|
|
44
44
|
liabilityLimit?: number | undefined;
|
|
45
45
|
}, {
|
|
46
46
|
perSource: SourceOutcome[];
|
|
47
47
|
summary: {
|
|
48
48
|
totalInput: number;
|
|
49
49
|
panelMatched: number;
|
|
50
|
-
bySeverity: Record<"
|
|
50
|
+
bySeverity: Record<"high" | "low" | "medium", number>;
|
|
51
51
|
byOrgan: Record<string, number>;
|
|
52
52
|
openTargetsWithLiabilities: number;
|
|
53
53
|
};
|
|
@@ -11,6 +11,8 @@
|
|
|
11
11
|
* accepts ONLY an Ensembl gene id, and it is taken from the panel entry when
|
|
12
12
|
* there is one and resolved from the gene symbol when there is not.
|
|
13
13
|
*/
|
|
14
|
+
import { errorMessageOf } from "../../lib/thrown.js";
|
|
15
|
+
import { textOf } from "../../lib/unknown-text.js";
|
|
14
16
|
import { ok } from "neverthrow";
|
|
15
17
|
import { z } from "zod";
|
|
16
18
|
import { ORGAN_SYSTEMS } from "../../contracts/organ-system.js";
|
|
@@ -19,12 +21,15 @@ import { CHEMBL_RE, SafetyPanelFileSchema, UNIPROT_RE } from "../../data/safety-
|
|
|
19
21
|
import panelData from "../../data/safety-panel.json" with { type: "json" };
|
|
20
22
|
import { defineTool } from "../define-tool.js";
|
|
21
23
|
import { resolveSymbolToEnsemblId } from "../lib/ensembl-client.js";
|
|
24
|
+
import { isAllDigits } from "../../lib/text.js";
|
|
22
25
|
import { getTargetSafetyLiabilities } from "../lib/opentargets-client.js";
|
|
23
26
|
const PANEL = SafetyPanelFileSchema.parse(panelData);
|
|
24
27
|
const BY_CHEMBL = new Map(PANEL.targets.map((t) => [t.chembl_id, t]));
|
|
25
28
|
const BY_GENE = new Map(PANEL.targets.map((t) => [t.gene_symbol, t]));
|
|
26
29
|
const BY_UNIPROT = new Map(PANEL.targets.map((t) => [t.uniprot, t]));
|
|
27
|
-
|
|
30
|
+
function isEnsemblGeneId(id) {
|
|
31
|
+
return id.startsWith("ENSG") && id.length === 15 && isAllDigits(id.slice(4));
|
|
32
|
+
}
|
|
28
33
|
/** Ordered weakest → strongest so `minSeverity` can be a numeric floor. */
|
|
29
34
|
const SEVERITY_ORDER = { low: 0, medium: 1, high: 2 };
|
|
30
35
|
const SOURCES = ["panel", "opentargets"];
|
|
@@ -35,7 +40,7 @@ const DEFAULT_LIABILITY_LIMIT = 10;
|
|
|
35
40
|
function detectType(id) {
|
|
36
41
|
if (CHEMBL_RE.test(id))
|
|
37
42
|
return "chembl_id";
|
|
38
|
-
if (
|
|
43
|
+
if (isEnsemblGeneId(id))
|
|
39
44
|
return "ensembl_id";
|
|
40
45
|
if (UNIPROT_RE.test(id))
|
|
41
46
|
return "uniprot";
|
|
@@ -84,7 +89,7 @@ const inputSchema = z
|
|
|
84
89
|
.optional()
|
|
85
90
|
.describe(`'opentargets' only. Max liabilities per target (default ${DEFAULT_LIABILITY_LIMIT}, max 100); \`liabilityCount\` gives the true total.`),
|
|
86
91
|
})
|
|
87
|
-
.refine((d) => (d.sources ?? [...SOURCES]).includes("opentargets")
|
|
92
|
+
.refine((d) => !(d.sources ?? [...SOURCES]).includes("opentargets") || d.identifiers.length <= MAX_OPENTARGETS_IDENTIFIERS, {
|
|
88
93
|
message: `identifiers is capped at ${MAX_OPENTARGETS_IDENTIFIERS} when source 'opentargets' is included (one request per target). ` +
|
|
89
94
|
`Either narrow the list, or pass sources: ['panel'] to sweep up to ${MAX_PANEL_IDENTIFIERS} against the local panel first and follow up on the hits.`,
|
|
90
95
|
path: ["identifiers"],
|
|
@@ -150,7 +155,7 @@ export const targetSafetyTool = defineTool({
|
|
|
150
155
|
row.liabilities = result.safetyLiabilities.slice(0, limit);
|
|
151
156
|
}
|
|
152
157
|
catch (error) {
|
|
153
|
-
opentargetsError = error
|
|
158
|
+
opentargetsError = errorMessageOf(error) ?? textOf(error);
|
|
154
159
|
row.opentargetsNote = "Open Targets could not be reached";
|
|
155
160
|
}
|
|
156
161
|
}));
|
|
@@ -175,7 +180,7 @@ export const targetSafetyTool = defineTool({
|
|
|
175
180
|
source: "opentargets",
|
|
176
181
|
status: opentargetsError ? "unavailable" : withLiabilities > 0 ? "ok" : "no_data",
|
|
177
182
|
matched: withLiabilities,
|
|
178
|
-
|
|
183
|
+
detail: opentargetsError,
|
|
179
184
|
});
|
|
180
185
|
}
|
|
181
186
|
return ok({
|
|
@@ -184,7 +189,7 @@ export const targetSafetyTool = defineTool({
|
|
|
184
189
|
totalInput: identifiers.length,
|
|
185
190
|
panelMatched,
|
|
186
191
|
bySeverity,
|
|
187
|
-
byOrgan
|
|
192
|
+
byOrgan,
|
|
188
193
|
openTargetsWithLiabilities: withLiabilities,
|
|
189
194
|
},
|
|
190
195
|
targets: rows,
|
|
@@ -13,24 +13,28 @@
|
|
|
13
13
|
* description. Where the ids reach an agent matters: a prompt names no dataset, so the knowledge
|
|
14
14
|
* arrives through a tool, which carries its own description into the context at attach time.
|
|
15
15
|
*/
|
|
16
|
+
import { z } from "zod";
|
|
16
17
|
import type { EnvironmentStorePaths } from "../config/environment-stores.js";
|
|
18
|
+
import { type Tool } from "./define-tool.js";
|
|
17
19
|
export type InspectCapabilityDataDeps = Pick<EnvironmentStorePaths, "refStorePath">;
|
|
18
20
|
/** One capability, its declared datasets, and what the store holds of them. */
|
|
19
|
-
export
|
|
21
|
+
export type CapabilityDataRow = {
|
|
20
22
|
readonly agentId: string;
|
|
21
23
|
readonly capability: string;
|
|
22
24
|
readonly installed: readonly string[];
|
|
23
25
|
readonly absent: readonly string[];
|
|
24
|
-
}
|
|
25
|
-
export
|
|
26
|
+
};
|
|
27
|
+
export type CapabilityDataResult = {
|
|
26
28
|
/** False when the store could not be answered for: every `absent` list is then unknown, not empty. */
|
|
27
29
|
readonly storeReadable: boolean;
|
|
28
30
|
readonly rows: readonly CapabilityDataRow[];
|
|
29
31
|
readonly content: string;
|
|
30
|
-
}
|
|
32
|
+
};
|
|
31
33
|
/**
|
|
32
34
|
* Build the tool. The store read happens per call, not at construction: a dataset installed during
|
|
33
35
|
* the conversation must show as installed on the next call, and a cached answer would have the
|
|
34
36
|
* agent offer a download the user already approved.
|
|
35
37
|
*/
|
|
36
|
-
|
|
38
|
+
declare const CapabilityDataInputSchema: z.ZodObject<{}, z.core.$strip>;
|
|
39
|
+
export declare function createInspectCapabilityDataTool(deps?: InspectCapabilityDataDeps): Tool<z.infer<typeof CapabilityDataInputSchema>, CapabilityDataResult>;
|
|
40
|
+
export {};
|
|
@@ -42,6 +42,7 @@ function renderRows(rows, storeReadable) {
|
|
|
42
42
|
* the conversation must show as installed on the next call, and a cached answer would have the
|
|
43
43
|
* agent offer a download the user already approved.
|
|
44
44
|
*/
|
|
45
|
+
const CapabilityDataInputSchema = z.object({});
|
|
45
46
|
export function createInspectCapabilityDataTool(deps = {}) {
|
|
46
47
|
return defineTool({
|
|
47
48
|
id: "inspect_capability_data",
|
|
@@ -50,7 +51,7 @@ export function createInspectCapabilityDataTool(deps = {}) {
|
|
|
50
51
|
"Each entry names a catalog dataset id, which is exactly what an install takes; a surface with a way to provision can act on it directly. " +
|
|
51
52
|
"It takes no arguments and the whole set is small, so one call is the complete answer. " +
|
|
52
53
|
"An unreadable store answers UNKNOWN rather than absent, so a store that cannot be read never reads as a store that holds nothing.",
|
|
53
|
-
inputSchema:
|
|
54
|
+
inputSchema: CapabilityDataInputSchema,
|
|
54
55
|
describeCall: () => "declared capability data",
|
|
55
56
|
execute: async () => {
|
|
56
57
|
const declared = declaredDataRequirements();
|