@inflexa-ai/harness 0.35.8 → 0.36.1

package/dist/workflows/target-assessment/steps/phase3-aggregate.d.ts

@@ -1,806 +0,0 @@
-/**
- * Phase 3 aggregator — schema definitions retained for downstream
- * type-checking. The DBOS workflow assembles the Phase-3 bundle inline.
- */
-import { z } from "zod";
-export declare const Phase3BundleSchema: z.ZodObject<{
-    phase2: z.ZodObject<{
-        phase1: z.ZodObject<{
-            resolved: z.ZodObject<{
-                assessmentId: z.ZodString;
-                goal: z.ZodNullable<z.ZodString>;
-                canonicalId: z.ZodString;
-                canonicalOntology: z.ZodEnum<{
-                    hgnc: "hgnc";
-                    ensembl: "ensembl";
-                }>;
-                geneSymbol: z.ZodString;
-                approvedName: z.ZodString;
-                ids: z.ZodObject<{
-                    hgnc: z.ZodNullable<z.ZodString>;
-                    ensembl: z.ZodNullable<z.ZodString>;
-                    uniprot: z.ZodNullable<z.ZodString>;
-                    chembl: z.ZodNullable<z.ZodString>;
-                    entrez: z.ZodNullable<z.ZodString>;
-                }, z.core.$strip>;
-                synonyms: z.ZodArray<z.ZodString>;
-                proteinSynonyms: z.ZodArray<z.ZodString>;
-                proteinFamily: z.ZodNullable<z.ZodString>;
-                resolutionCoverage: z.ZodObject<{
-                    hgnc: z.ZodBoolean;
-                    uniprot: z.ZodBoolean;
-                    ensembl: z.ZodBoolean;
-                    chembl: z.ZodBoolean;
-                }, z.core.$strip>;
-            }, z.core.$strip>;
-            collectors: z.ZodObject<{
-                opentargets: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                    coverage: z.ZodLiteral<"available">;
-                    data: z.ZodObject<{
-                        ensemblId: z.ZodString;
-                        approvedSymbol: z.ZodString;
-                        approvedName: z.ZodString;
-                        tractability: z.ZodNullable<z.ZodObject<{
-                            smallMolecule: z.ZodNullable<z.ZodBoolean>;
-                            antibody: z.ZodNullable<z.ZodBoolean>;
-                            otherModalities: z.ZodNullable<z.ZodBoolean>;
-                        }, z.core.$strip>>;
-                        associations: z.ZodArray<z.ZodObject<{
-                            diseaseId: z.ZodString;
-                            diseaseName: z.ZodString;
-                            score: z.ZodNumber;
-                            geneticAssociationScore: z.ZodNullable<z.ZodNumber>;
-                            knownDrugScore: z.ZodNullable<z.ZodNumber>;
-                            literatureScore: z.ZodNullable<z.ZodNumber>;
-                            animalModelScore: z.ZodDefault<z.ZodNullable<z.ZodNumber>>;
-                            somaticMutationScore: z.ZodDefault<z.ZodNullable<z.ZodNumber>>;
-                            literaturePmids: z.ZodDefault<z.ZodArray<z.ZodString>>;
-                        }, z.core.$strip>>;
-                        safetyLiabilities: z.ZodArray<z.ZodObject<{
-                            event: z.ZodString;
-                            biosamples: z.ZodArray<z.ZodString>;
-                            effects: z.ZodNullable<z.ZodString>;
-                            source: z.ZodString;
-                        }, z.core.$strip>>;
-                        baselineExpression: z.ZodArray<z.ZodObject<{
-                            tissueId: z.ZodString;
-                            tissueLabel: z.ZodString;
-                            organSystem: z.ZodNullable<z.ZodString>;
-                            datasourceId: z.ZodString;
-                            rna: z.ZodNullable<z.ZodObject<{
-                                value: z.ZodNumber;
-                                unit: z.ZodString;
-                            }, z.core.$strip>>;
-                        }, z.core.$strip>>;
-                    }, z.core.$strip>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"queried_no_data">;
-                    error: z.ZodOptional<z.ZodObject<{
-                        message: z.ZodString;
-                        name: z.ZodOptional<z.ZodString>;
-                        stack: z.ZodOptional<z.ZodString>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"not_loaded">;
-                    reason: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>], "coverage">;
-                chemblModulators: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                    coverage: z.ZodLiteral<"available">;
-                    data: z.ZodObject<{
-                        targetChemblId: z.ZodNullable<z.ZodString>;
-                        modulators: z.ZodArray<z.ZodObject<{
-                            moleculeChemblId: z.ZodString;
-                            parentChemblId: z.ZodNullable<z.ZodString>;
-                            preferredName: z.ZodNullable<z.ZodString>;
-                            maxPhase: z.ZodNullable<z.ZodNumber>;
-                            moleculeType: z.ZodNullable<z.ZodString>;
-                            firstApproval: z.ZodNullable<z.ZodNumber>;
-                            evidence_source: z.ZodOptional<z.ZodLiteral<"chembl_activity">>;
-                        }, z.core.$strip>>;
-                    }, z.core.$strip>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"queried_no_data">;
-                    error: z.ZodOptional<z.ZodObject<{
-                        message: z.ZodString;
-                        name: z.ZodOptional<z.ZodString>;
-                        stack: z.ZodOptional<z.ZodString>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"not_loaded">;
-                    reason: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>], "coverage">;
-                ctgov: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                    coverage: z.ZodLiteral<"available">;
-                    data: z.ZodObject<{
-                        active: z.ZodArray<z.ZodObject<{
-                            nctId: z.ZodString;
-                            title: z.ZodString;
-                            officialTitle: z.ZodNullable<z.ZodString>;
-                            status: z.ZodString;
-                            phase: z.ZodNullable<z.ZodString>;
-                            studyType: z.ZodNullable<z.ZodString>;
-                            primaryPurpose: z.ZodNullable<z.ZodString>;
-                            conditions: z.ZodArray<z.ZodString>;
-                            interventions: z.ZodArray<z.ZodString>;
-                            interventionDetails: z.ZodArray<z.ZodObject<{
-                                name: z.ZodString;
-                                type: z.ZodNullable<z.ZodString>;
-                                description: z.ZodNullable<z.ZodString>;
-                                otherNames: z.ZodArray<z.ZodString>;
-                            }, z.core.$strip>>;
-                            enrollmentCount: z.ZodNullable<z.ZodNumber>;
-                            startDate: z.ZodNullable<z.ZodString>;
-                            primaryCompletionDate: z.ZodNullable<z.ZodString>;
-                            whyStopped: z.ZodNullable<z.ZodString>;
-                            briefSummary: z.ZodNullable<z.ZodString>;
-                            detailedDescription: z.ZodNullable<z.ZodString>;
-                            sponsor: z.ZodNullable<z.ZodString>;
-                            collection_query: z.ZodOptional<z.ZodString>;
-                            collection_channel: z.ZodOptional<z.ZodEnum<{
-                                class_modulator: "class_modulator";
-                                target_symbol: "target_symbol";
-                                therapeutic_program: "therapeutic_program";
-                                biomarker_context: "biomarker_context";
-                                failed_intervention: "failed_intervention";
-                            }>>;
-                        }, z.core.$strip>>;
-                        failed: z.ZodArray<z.ZodObject<{
-                            nctId: z.ZodString;
-                            title: z.ZodString;
-                            officialTitle: z.ZodNullable<z.ZodString>;
-                            status: z.ZodString;
-                            phase: z.ZodNullable<z.ZodString>;
-                            studyType: z.ZodNullable<z.ZodString>;
-                            primaryPurpose: z.ZodNullable<z.ZodString>;
-                            conditions: z.ZodArray<z.ZodString>;
-                            interventions: z.ZodArray<z.ZodString>;
-                            interventionDetails: z.ZodArray<z.ZodObject<{
-                                name: z.ZodString;
-                                type: z.ZodNullable<z.ZodString>;
-                                description: z.ZodNullable<z.ZodString>;
-                                otherNames: z.ZodArray<z.ZodString>;
-                            }, z.core.$strip>>;
-                            enrollmentCount: z.ZodNullable<z.ZodNumber>;
-                            startDate: z.ZodNullable<z.ZodString>;
-                            primaryCompletionDate: z.ZodNullable<z.ZodString>;
-                            whyStopped: z.ZodNullable<z.ZodString>;
-                            briefSummary: z.ZodNullable<z.ZodString>;
-                            detailedDescription: z.ZodNullable<z.ZodString>;
-                            sponsor: z.ZodNullable<z.ZodString>;
-                            collection_query: z.ZodOptional<z.ZodString>;
-                            collection_channel: z.ZodOptional<z.ZodEnum<{
-                                class_modulator: "class_modulator";
-                                target_symbol: "target_symbol";
-                                therapeutic_program: "therapeutic_program";
-                                biomarker_context: "biomarker_context";
-                                failed_intervention: "failed_intervention";
-                            }>>;
-                        }, z.core.$strip>>;
-                    }, z.core.$strip>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"queried_no_data">;
-                    error: z.ZodOptional<z.ZodObject<{
-                        message: z.ZodString;
-                        name: z.ZodOptional<z.ZodString>;
-                        stack: z.ZodOptional<z.ZodString>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"not_loaded">;
-                    reason: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>], "coverage">;
-                faersByTarget: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                    coverage: z.ZodLiteral<"available">;
-                    data: z.ZodObject<{
-                        drugProbed: z.ZodString;
-                        totalReports: z.ZodNullable<z.ZodNumber>;
-                        topReactions: z.ZodArray<z.ZodObject<{
-                            reaction: z.ZodString;
-                            count: z.ZodNumber;
-                        }, z.core.$strip>>;
-                        seriousness: z.ZodNullable<z.ZodObject<{
-                            totalReports: z.ZodNumber;
-                            fatalCount: z.ZodNumber;
-                            hospitalizationCount: z.ZodNumber;
-                            lifeThreateningCount: z.ZodNumber;
-                            disablingCount: z.ZodNumber;
-                            congenitalAnomalyCount: z.ZodDefault<z.ZodNumber>;
-                            otherSeriousCount: z.ZodDefault<z.ZodNumber>;
-                        }, z.core.$strip>>;
-                    }, z.core.$strip>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"queried_no_data">;
-                    error: z.ZodOptional<z.ZodObject<{
-                        message: z.ZodString;
-                        name: z.ZodOptional<z.ZodString>;
-                        stack: z.ZodOptional<z.ZodString>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"not_loaded">;
-                    reason: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>], "coverage">;
-                expressionHuman: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                    coverage: z.ZodLiteral<"available">;
-                    data: z.ZodObject<{
-                        source: z.ZodEnum<{
-                            gtex: "gtex";
-                            hpa_consensus: "hpa_consensus";
-                            hpa_rna_tissue: "hpa_rna_tissue";
-                        }>;
-                        unit: z.ZodEnum<{
-                            tpm: "tpm";
-                            ntpm: "ntpm";
-                            consensus_normalized: "consensus_normalized";
-                        }>;
-                        normalization_notes: z.ZodString;
-                        tissues: z.ZodArray<z.ZodObject<{
-                            tissueLabel: z.ZodString;
-                            organSystem: z.ZodNullable<z.ZodString>;
-                            value: z.ZodNullable<z.ZodNumber>;
-                        }, z.core.$strip>>;
-                    }, z.core.$strip>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"queried_no_data">;
-                    error: z.ZodOptional<z.ZodObject<{
-                        message: z.ZodString;
-                        name: z.ZodOptional<z.ZodString>;
-                        stack: z.ZodOptional<z.ZodString>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"not_loaded">;
-                    reason: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>], "coverage">;
-                expressionMultiSpecies: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                    coverage: z.ZodLiteral<"available">;
-                    data: z.ZodObject<{
-                        geneSymbol: z.ZodString;
-                        humanEnsemblId: z.ZodNullable<z.ZodString>;
-                        bySpecies: z.ZodArray<z.ZodObject<{
-                            species: z.ZodString;
-                            taxonId: z.ZodNumber;
-                            ensemblId: z.ZodString;
-                            source: z.ZodString;
-                            unit: z.ZodString;
-                            normalization_notes: z.ZodString;
-                            tissues: z.ZodArray<z.ZodObject<{
-                                tissue: z.ZodString;
-                                rank: z.ZodEnum<{
-                                    low: "low";
-                                    medium: "medium";
-                                    high: "high";
-                                    absent: "absent";
-                                }>;
-                                expressionScore: z.ZodNullable<z.ZodNumber>;
-                            }, z.core.$strip>>;
-                        }, z.core.$strip>>;
-                        notFound: z.ZodArray<z.ZodString>;
-                    }, z.core.$strip>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"queried_no_data">;
-                    error: z.ZodOptional<z.ZodObject<{
-                        message: z.ZodString;
-                        name: z.ZodOptional<z.ZodString>;
-                        stack: z.ZodOptional<z.ZodString>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"not_loaded">;
-                    reason: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>], "coverage">;
-                clinvar: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                    coverage: z.ZodLiteral<"available">;
-                    data: z.ZodObject<{
-                        totalFound: z.ZodNumber;
-                        variants: z.ZodArray<z.ZodObject<{
-                            variationId: z.ZodString;
-                            title: z.ZodString;
-                            clinicalSignificance: z.ZodString;
-                            reviewStatus: z.ZodString;
-                            conditions: z.ZodArray<z.ZodString>;
-                            molecularConsequence: z.ZodString;
-                            accession: z.ZodString;
-                        }, z.core.$strip>>;
-                    }, z.core.$strip>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"queried_no_data">;
-                    error: z.ZodOptional<z.ZodObject<{
-                        message: z.ZodString;
-                        name: z.ZodOptional<z.ZodString>;
-                        stack: z.ZodOptional<z.ZodString>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"not_loaded">;
-                    reason: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>], "coverage">;
-                cbioportal: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                    coverage: z.ZodLiteral<"available">;
-                    data: z.ZodObject<{
-                        entrezGeneId: z.ZodNullable<z.ZodNumber>;
-                        rows: z.ZodArray<z.ZodObject<{
-                            cancerTypeId: z.ZodString;
-                            cancerTypeName: z.ZodString;
-                            totalSamples: z.ZodNumber;
-                            mutatedSamples: z.ZodNumber;
-                            frequency: z.ZodNumber;
-                            studies: z.ZodArray<z.ZodString>;
-                        }, z.core.$strip>>;
-                    }, z.core.$strip>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"queried_no_data">;
-                    error: z.ZodOptional<z.ZodObject<{
-                        message: z.ZodString;
-                        name: z.ZodOptional<z.ZodString>;
-                        stack: z.ZodOptional<z.ZodString>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"not_loaded">;
-                    reason: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>], "coverage">;
-                impc: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                    coverage: z.ZodLiteral<"available">;
-                    data: z.ZodObject<{
-                        mouseMarkerSymbol: z.ZodNullable<z.ZodString>;
-                        mgiAccessionId: z.ZodNullable<z.ZodString>;
-                        viability: z.ZodNullable<z.ZodEnum<{
-                            lethal_pre_weaning: "lethal_pre_weaning";
-                            subviable: "subviable";
-                            viable: "viable";
-                        }>>;
-                        viabilityCalls: z.ZodArray<z.ZodObject<{
-                            zygosity: z.ZodString;
-                            parameterStableId: z.ZodString;
-                            mpTerm: z.ZodNullable<z.ZodObject<{
-                                id: z.ZodString;
-                                name: z.ZodString;
-                            }, z.core.$strip>>;
-                        }, z.core.$strip>>;
-                        mpTerms: z.ZodArray<z.ZodObject<{
-                            id: z.ZodString;
-                            term: z.ZodString;
-                            bestPValue: z.ZodNullable<z.ZodNumber>;
-                        }, z.core.$strip>>;
-                        organSystems: z.ZodArray<z.ZodString>;
-                        sexDimorphic: z.ZodBoolean;
-                        phenotypeCount: z.ZodNumber;
-                    }, z.core.$strip>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"queried_no_data">;
-                    error: z.ZodOptional<z.ZodObject<{
-                        message: z.ZodString;
-                        name: z.ZodOptional<z.ZodString>;
-                        stack: z.ZodOptional<z.ZodString>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"not_loaded">;
-                    reason: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>], "coverage">;
-                pubmedIndex: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                    coverage: z.ZodLiteral<"available">;
-                    data: z.ZodObject<{
-                        totalFound: z.ZodNumber;
-                        topPmids: z.ZodArray<z.ZodString>;
-                        results: z.ZodArray<z.ZodObject<{
-                            pmid: z.ZodString;
-                            title: z.ZodString;
-                            journal: z.ZodString;
-                            year: z.ZodString;
-                            authors: z.ZodString;
-                        }, z.core.$strip>>;
-                    }, z.core.$strip>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"queried_no_data">;
-                    error: z.ZodOptional<z.ZodObject<{
-                        message: z.ZodString;
-                        name: z.ZodOptional<z.ZodString>;
-                        stack: z.ZodOptional<z.ZodString>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"not_loaded">;
-                    reason: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>], "coverage">;
-                pathways: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                    coverage: z.ZodLiteral<"available">;
-                    data: z.ZodObject<{
-                        pathways: z.ZodArray<z.ZodObject<{
-                            id: z.ZodString;
-                            name: z.ZodString;
-                            source: z.ZodEnum<{
-                                kegg: "kegg";
-                                reactome: "reactome";
-                            }>;
-                            url: z.ZodOptional<z.ZodString>;
-                            entity_uniprots: z.ZodOptional<z.ZodArray<z.ZodString>>;
-                            metadata: z.ZodOptional<z.ZodObject<{
-                                species_present: z.ZodOptional<z.ZodArray<z.ZodString>>;
-                            }, z.core.$strip>>;
-                        }, z.core.$strip>>;
-                    }, z.core.$strip>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"queried_no_data">;
-                    error: z.ZodOptional<z.ZodObject<{
-                        message: z.ZodString;
-                        name: z.ZodOptional<z.ZodString>;
-                        stack: z.ZodOptional<z.ZodString>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"not_loaded">;
-                    reason: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>], "coverage">;
-                stringPpi: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                    coverage: z.ZodLiteral<"available">;
-                    data: z.ZodObject<{
-                        partners: z.ZodArray<z.ZodObject<{
-                            proteinA: z.ZodString;
-                            proteinB: z.ZodString;
-                            score: z.ZodNumber;
-                            experimentalScore: z.ZodOptional<z.ZodNumber>;
-                            databaseScore: z.ZodOptional<z.ZodNumber>;
-                            textminingScore: z.ZodOptional<z.ZodNumber>;
-                        }, z.core.$strip>>;
-                    }, z.core.$strip>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"queried_no_data">;
-                    error: z.ZodOptional<z.ZodObject<{
-                        message: z.ZodString;
-                        name: z.ZodOptional<z.ZodString>;
-                        stack: z.ZodOptional<z.ZodString>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"not_loaded">;
-                    reason: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>], "coverage">;
-                familyComplexes: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                    coverage: z.ZodLiteral<"available">;
-                    data: z.ZodObject<{
-                        primaryTargetGene: z.ZodString;
-                        primaryTargetUniprot: z.ZodNullable<z.ZodString>;
-                        accessoryProteinNames: z.ZodArray<z.ZodString>;
-                        complexes: z.ZodArray<z.ZodObject<{
-                            complexName: z.ZodString;
-                            complexId: z.ZodNullable<z.ZodNumber>;
-                            accessoryNames: z.ZodArray<z.ZodString>;
-                            subunitNames: z.ZodArray<z.ZodString>;
-                        }, z.core.$strip>>;
-                    }, z.core.$strip>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"queried_no_data">;
-                    error: z.ZodOptional<z.ZodObject<{
-                        message: z.ZodString;
-                        name: z.ZodOptional<z.ZodString>;
-                        stack: z.ZodOptional<z.ZodString>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"not_loaded">;
-                    reason: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>], "coverage">;
-                monarch: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                    coverage: z.ZodLiteral<"available">;
-                    data: z.ZodObject<{
-                        geneCurie: z.ZodString;
-                        phenotypes: z.ZodArray<z.ZodObject<{
-                            hpoId: z.ZodString;
-                            label: z.ZodString;
-                            ancestorIds: z.ZodArray<z.ZodString>;
-                            publications: z.ZodArray<z.ZodString>;
-                            diseaseContext: z.ZodNullable<z.ZodString>;
-                            frequencyPercent: z.ZodNullable<z.ZodNumber>;
-                            primaryKnowledgeSource: z.ZodNullable<z.ZodString>;
-                        }, z.core.$strip>>;
-                    }, z.core.$strip>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"queried_no_data">;
-                    error: z.ZodOptional<z.ZodObject<{
-                        message: z.ZodString;
-                        name: z.ZodOptional<z.ZodString>;
-                        stack: z.ZodOptional<z.ZodString>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"not_loaded">;
-                    reason: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>], "coverage">;
-                therapeuticPrograms: z.ZodOptional<z.ZodDiscriminatedUnion<[z.ZodObject<{
-                    coverage: z.ZodLiteral<"available">;
-                    data: z.ZodObject<{
-                        programs: z.ZodArray<z.ZodObject<{
-                            programId: z.ZodString;
-                            name: z.ZodString;
-                            targetSymbol: z.ZodString;
-                            targetUniprot: z.ZodNullable<z.ZodString>;
-                            modality: z.ZodString;
-                            sponsor: z.ZodNullable<z.ZodString>;
-                            mechanism: z.ZodString;
-                            status: z.ZodString;
-                            nctIds: z.ZodArray<z.ZodString>;
-                            pmids: z.ZodArray<z.ZodString>;
-                            evidence: z.ZodArray<z.ZodObject<{
-                                pmid: z.ZodOptional<z.ZodString>;
-                                doi: z.ZodOptional<z.ZodString>;
-                                accession: z.ZodOptional<z.ZodString>;
-                                source: z.ZodString;
-                                predicate: z.ZodOptional<z.ZodString>;
-                                score: z.ZodOptional<z.ZodNumber>;
-                                strength: z.ZodOptional<z.ZodString>;
-                                is_human: z.ZodOptional<z.ZodBoolean>;
-                                is_clinical: z.ZodOptional<z.ZodBoolean>;
-                                excerpt: z.ZodOptional<z.ZodString>;
-                                metadata: z.ZodOptional<z.ZodRecord<z.ZodString, z.ZodUnknown>>;
-                                regulatory_reference: z.ZodOptional<z.ZodObject<{
-                                    document: z.ZodString;
-                                    section: z.ZodOptional<z.ZodString>;
-                                    doc_id: z.ZodOptional<z.ZodString>;
-                                    doc_url: z.ZodOptional<z.ZodString>;
-                                }, z.core.$strip>>;
-                            }, z.core.$strip>>;
-                            confidence: z.ZodEnum<{
-                                low: "low";
-                                medium: "medium";
-                                high: "high";
-                            }>;
-                        }, z.core.$strip>>;
-                    }, z.core.$strip>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"queried_no_data">;
-                    error: z.ZodOptional<z.ZodObject<{
-                        message: z.ZodString;
-                        name: z.ZodOptional<z.ZodString>;
-                        stack: z.ZodOptional<z.ZodString>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>, z.ZodObject<{
-                    coverage: z.ZodLiteral<"not_loaded">;
-                    reason: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>], "coverage">>;
-            }, z.core.$strip>;
-        }, z.core.$strip>;
-        decisions: z.ZodObject<{
-            modulatorTriage: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    shortlist: z.ZodArray<z.ZodObject<{
-                        moleculeChemblId: z.ZodString;
-                        preferredName: z.ZodString;
-                        maxPhase: z.ZodNullable<z.ZodNumber>;
-                        firstApproval: z.ZodNullable<z.ZodNumber>;
-                        rationale: z.ZodString;
-                    }, z.core.$strip>>;
-                    notes: z.ZodString;
-                    dropped_synonyms: z.ZodDefault<z.ZodArray<z.ZodObject<{
-                        chemblId: z.ZodString;
-                        reason: z.ZodEnum<{
-                            same_active_substance: "same_active_substance";
-                            ambiguous_name_synonym: "ambiguous_name_synonym";
-                        }>;
-                        keptId: z.ZodNullable<z.ZodString>;
-                    }, z.core.$strip>>>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">;
-            failedTrialClassifier: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    classifications: z.ZodDefault<z.ZodArray<z.ZodUnknown>>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">;
-            offTargetCurator: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    panel: z.ZodDefault<z.ZodArray<z.ZodUnknown>>;
-                    total: z.ZodDefault<z.ZodNumber>;
-                    truncated: z.ZodDefault<z.ZodBoolean>;
-                    notes: z.ZodDefault<z.ZodString>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">;
-            drugsInClass: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    drugs: z.ZodArray<z.ZodObject<{
-                        moleculeChemblId: z.ZodString;
-                        preferredName: z.ZodString;
-                        maxPhase: z.ZodNullable<z.ZodNumber>;
-                        firstApproval: z.ZodNullable<z.ZodNumber>;
-                        moleculeType: z.ZodNullable<z.ZodString>;
-                        sources: z.ZodArray<z.ZodEnum<{
-                            dgidb: "dgidb";
-                            drugbank: "drugbank";
-                            chembl: "chembl";
-                        }>>;
-                    }, z.core.$strip>>;
-                    total: z.ZodNumber;
-                    truncated: z.ZodBoolean;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">;
-        }, z.core.$strip>;
-    }, z.core.$strip>;
-    fanout: z.ZodObject<{
-        perModulatorFaers: z.ZodObject<{
-            results: z.ZodArray<z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    moleculeChemblId: z.ZodString;
-                    preferredName: z.ZodString;
-                    totalReports: z.ZodNullable<z.ZodNumber>;
-                    topReactions: z.ZodArray<z.ZodObject<{
-                        reaction: z.ZodString;
-                        count: z.ZodNumber;
-                    }, z.core.$strip>>;
-                    seriousness: z.ZodNullable<z.ZodObject<{
-                        totalReports: z.ZodNumber;
-                        fatalCount: z.ZodNumber;
-                        hospitalizationCount: z.ZodNumber;
-                        lifeThreateningCount: z.ZodNumber;
-                        disablingCount: z.ZodNumber;
-                        congenitalAnomalyCount: z.ZodDefault<z.ZodNumber>;
-                        otherSeriousCount: z.ZodDefault<z.ZodNumber>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">>;
-        }, z.core.$strip>;
-        perTrialAes: z.ZodObject<{
-            results: z.ZodArray<z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    nctId: z.ZodString;
-                    title: z.ZodString;
-                    whyStopped: z.ZodNullable<z.ZodString>;
-                    outcomes: z.ZodDefault<z.ZodArray<z.ZodObject<{
-                        type: z.ZodEnum<{
-                            other: "other";
-                            primary: "primary";
-                            secondary: "secondary";
-                        }>;
-                        measure: z.ZodString;
-                        description: z.ZodNullable<z.ZodString>;
-                        timeFrame: z.ZodNullable<z.ZodString>;
-                        effect: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                            kind: z.ZodLiteral<"quantitative">;
-                            value: z.ZodNumber;
-                            units: z.ZodString;
-                            ci_low: z.ZodOptional<z.ZodNumber>;
-                            ci_high: z.ZodOptional<z.ZodNumber>;
-                        }, z.core.$strip>, z.ZodObject<{
-                            kind: z.ZodLiteral<"not_extracted">;
-                            reason: z.ZodEnum<{
-                                ctgov_no_numeric_result: "ctgov_no_numeric_result";
-                                ctgov_no_result_groups: "ctgov_no_result_groups";
-                            }>;
-                        }, z.core.$strip>], "kind">;
-                    }, z.core.$strip>>>;
-                    groups: z.ZodArray<z.ZodObject<{
-                        groupId: z.ZodString;
-                        title: z.ZodString;
-                        description: z.ZodNullable<z.ZodString>;
-                    }, z.core.$strip>>;
-                    events: z.ZodArray<z.ZodObject<{
-                        serious: z.ZodBoolean;
-                        term: z.ZodString;
-                        organSystem: z.ZodNullable<z.ZodString>;
-                        counts: z.ZodArray<z.ZodObject<{
-                            groupId: z.ZodString;
-                            numAffected: z.ZodNullable<z.ZodNumber>;
-                            numAtRisk: z.ZodNullable<z.ZodNumber>;
-                        }, z.core.$strip>>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">>;
-        }, z.core.$strip>;
-        perModulatorPolypharm: z.ZodObject<{
-            results: z.ZodArray<z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    moleculeChemblId: z.ZodString;
-                    preferredName: z.ZodString;
-                    primaryPchembl: z.ZodNullable<z.ZodNumber>;
-                    hits: z.ZodArray<z.ZodObject<{
-                        targetChemblId: z.ZodString;
-                        targetName: z.ZodNullable<z.ZodString>;
-                        assayChemblId: z.ZodNullable<z.ZodString>;
-                        pchemblValue: z.ZodNullable<z.ZodNumber>;
-                        standardType: z.ZodNullable<z.ZodString>;
-                        standardValue: z.ZodNullable<z.ZodNumber>;
-                        standardUnits: z.ZodNullable<z.ZodString>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">>;
-        }, z.core.$strip>;
-        perClassDrugAes: z.ZodObject<{
-            results: z.ZodArray<z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    moleculeChemblId: z.ZodString;
-                    preferredName: z.ZodString;
-                    totalReports: z.ZodNullable<z.ZodNumber>;
-                    topReactions: z.ZodArray<z.ZodObject<{
-                        reaction: z.ZodString;
-                        count: z.ZodNumber;
-                    }, z.core.$strip>>;
-                    seriousness: z.ZodNullable<z.ZodObject<{
-                        totalReports: z.ZodNumber;
-                        fatalCount: z.ZodNumber;
-                        hospitalizationCount: z.ZodNumber;
-                        lifeThreateningCount: z.ZodNumber;
-                        disablingCount: z.ZodNumber;
-                        congenitalAnomalyCount: z.ZodDefault<z.ZodNumber>;
-                        otherSeriousCount: z.ZodDefault<z.ZodNumber>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">>;
-        }, z.core.$strip>;
-    }, z.core.$strip>;
-}, z.core.$strip>;
-export type Phase3Bundle = z.infer<typeof Phase3BundleSchema>;