@inflexa-ai/harness 0.29.0 → 0.30.1
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/dist/agents/conversation-agent.js +7 -4
- package/dist/agents/report-session-agent.js +1 -1
- package/dist/agents/sandbox/data-profiler.js +0 -1
- package/dist/agents/sandbox/immune-profiling-agent.js +3 -1
- package/dist/agents/sandbox/network-agent.js +0 -1
- package/dist/agents/sandbox/types.d.ts +1 -1
- package/dist/agents/sandbox/types.js +1 -1
- package/dist/config/resource-limits.d.ts +1 -1
- package/dist/config/resource-limits.js +1 -1
- package/dist/contracts/schemas/chat-parts.d.ts +12 -12
- package/dist/contracts/severity.d.ts +2 -2
- package/dist/contracts/target-dossier.d.ts +70 -70
- package/dist/data/safety-panel-schema.d.ts +4 -4
- package/dist/index.d.ts +2 -1
- package/dist/index.js +9 -0
- package/dist/loop/run-agent.d.ts +14 -1
- package/dist/loop/run-agent.js +6 -1
- package/dist/prompts/SOUL.d.ts +2 -2
- package/dist/prompts/SOUL.js +17 -1
- package/dist/prompts/conversation.d.ts +1 -1
- package/dist/prompts/conversation.js +43 -71
- package/dist/prompts/planner.js +57 -10
- package/dist/prompts/sandbox/bulk-transcriptomics-agent.d.ts +1 -1
- package/dist/prompts/sandbox/bulk-transcriptomics-agent.js +3 -1
- package/dist/prompts/sandbox/dna-methylation-agent.d.ts +1 -1
- package/dist/prompts/sandbox/dna-methylation-agent.js +18 -12
- package/dist/prompts/sandbox/immune-profiling-agent.d.ts +1 -1
- package/dist/prompts/sandbox/immune-profiling-agent.js +6 -2
- package/dist/prompts/sandbox/metabolomics-agent.d.ts +1 -1
- package/dist/prompts/sandbox/metabolomics-agent.js +8 -4
- package/dist/prompts/sandbox/microbiome-agent.d.ts +1 -1
- package/dist/prompts/sandbox/microbiome-agent.js +12 -6
- package/dist/prompts/sandbox/network-agent.d.ts +1 -1
- package/dist/prompts/sandbox/network-agent.js +9 -6
- package/dist/prompts/sandbox/spatial-omics-agent.d.ts +1 -1
- package/dist/prompts/sandbox/spatial-omics-agent.js +4 -2
- package/dist/providers/ai-sdk.js +4 -0
- package/dist/providers/reasoning.d.ts +35 -0
- package/dist/providers/reasoning.js +34 -0
- package/dist/providers/types.d.ts +26 -0
- package/dist/schemas/data-profile-schemas.d.ts +4 -4
- package/dist/schemas/run-synthesis.d.ts +4 -4
- package/dist/tools/bio/chembl.d.ts +1 -1
- package/dist/tools/bio/chembl.js +15 -10
- package/dist/tools/bio/comptox.js +5 -1
- package/dist/tools/bio/drug-gene-interactions.js +5 -2
- package/dist/tools/bio/gene-disease-evidence.d.ts +19 -9
- package/dist/tools/bio/gene-disease-evidence.js +78 -22
- package/dist/tools/bio/gene-preclinical-profile.d.ts +33 -13
- package/dist/tools/bio/gene-preclinical-profile.js +63 -22
- package/dist/tools/bio/lookup-annotation.d.ts +1 -0
- package/dist/tools/bio/lookup-annotation.js +28 -10
- package/dist/tools/bio/opentargets.d.ts +10 -2
- package/dist/tools/bio/opentargets.js +42 -13
- package/dist/tools/bio/pubchem.js +5 -2
- package/dist/tools/bio/pubmed.js +9 -3
- package/dist/tools/bio/search-clinical-trials.d.ts +25 -25
- package/dist/tools/bio/search-clinical-trials.js +56 -18
- package/dist/tools/bio/search-faers.d.ts +26 -6
- package/dist/tools/bio/search-faers.js +70 -18
- package/dist/tools/bio/search-gene.d.ts +19 -3
- package/dist/tools/bio/search-gene.js +69 -12
- package/dist/tools/bio/search-geo-datasets.js +4 -1
- package/dist/tools/bio/search-interactions.js +6 -2
- package/dist/tools/bio/target-safety.d.ts +2 -2
- package/dist/tools/bio/target-safety.js +3 -2
- package/dist/tools/lib/cbioportal-client.js +25 -6
- package/dist/tools/lib/chembl-client.d.ts +3 -1
- package/dist/tools/lib/chembl-client.js +6 -1
- package/dist/tools/lib/gwas-catalog-client.d.ts +7 -6
- package/dist/tools/lib/gwas-catalog-client.js +18 -6
- package/dist/tools/lib/openfda-client.d.ts +7 -5
- package/dist/tools/lib/openfda-client.js +17 -9
- package/dist/tools/lib/opentargets-client.d.ts +20 -0
- package/dist/tools/lib/opentargets-client.js +45 -0
- package/dist/tools/lib/pathway-client.d.ts +7 -0
- package/dist/tools/lib/pathway-client.js +68 -1
- package/dist/tools/research/context7-docs.js +3 -3
- package/dist/tools/research/generate-analogy-report.js +2 -2
- package/dist/tools/research/generate-plan.d.ts +3 -0
- package/dist/tools/research/generate-plan.js +64 -5
- package/dist/tools/research/resolve-citation.js +8 -3
- package/dist/tools/research/search-arxiv.js +8 -3
- package/dist/tools/research/search-semantic-scholar.js +10 -4
- package/dist/workflows/sandbox-step.d.ts +6 -0
- package/dist/workflows/sandbox-step.js +31 -14
- package/dist/workflows/target-assessment/assemblers/safety.d.ts +1 -1
- package/dist/workflows/target-assessment/phase4-assemble.d.ts +17 -17
- package/dist/workflows/target-assessment/schemas.d.ts +12 -12
- package/dist/workflows/target-assessment/steps/phase2-aggregate.d.ts +6 -6
- package/dist/workflows/target-assessment/steps/phase3-aggregate.d.ts +6 -6
- package/dist/workflows/target-assessment/synthesis/index.d.ts +12 -12
- package/package.json +1 -1
|
@@ -27,7 +27,7 @@ import { composeSystemPrompt } from "./system-prompt.js";
|
|
|
27
27
|
import { searchGeneTool, lookupAnnotationTool, searchInteractionsTool, chemblTool, pubchemTool, openTargetsTool, searchFaersTool, searchClinicalTrialsTool, searchGeoDatasetsTool, genePreclinicalProfileTool, targetSafetyTool, } from "../tools/bio/index.js";
|
|
28
28
|
import { createNcbiTools, createChemDbTools } from "../tools/bio/keys.js";
|
|
29
29
|
// Dependency-bearing tool factories.
|
|
30
|
-
import { createGeneratePlanTool,
|
|
30
|
+
import { createGeneratePlanTool, createInspectRunTool, createInspectDataProfileTool, createGenerateAnalogyReportTool, createSearchSemanticScholarTool, searchArxivTool, } from "../tools/research/index.js";
|
|
31
31
|
import { createFileStatTool, createGrepTool, createListFilesTool, createReadFileTool, createShowPlanTool, createWorkspaceSearchTool, showFileTool, } from "../tools/workspace/index.js";
|
|
32
32
|
import { showUserTool } from "../tools/display/index.js";
|
|
33
33
|
import { createUpdateWorkingMemoryTool } from "../tools/memory/index.js";
|
|
@@ -39,7 +39,7 @@ import { createResolveCitationTool } from "../tools/research/resolve-citation.js
|
|
|
39
39
|
/** Canonical agent id — the single source of truth. */
|
|
40
40
|
export const CONVERSATION_AGENT_ID = "conversation-agent";
|
|
41
41
|
/** Runaway guard — heavy tool-driving turns need generous headroom. */
|
|
42
|
-
const CONVERSATION_MAX_ITERATIONS =
|
|
42
|
+
const CONVERSATION_MAX_ITERATIONS = 200;
|
|
43
43
|
/** Build the conversation `AgentDefinition` with every tool fully dep-bound. */
|
|
44
44
|
export function createConversationAgent(deps) {
|
|
45
45
|
const { provider, pool, embedding, workspaceFs, model, utilityProvider, utilityModel, executeAnalysisWorkflow, runAuthorizer, runLauncher, bioKeys, chrome, resourcePolicy, hostTools, refStorePath, packagesFile, usageRecorder, citationResolver, } = deps;
|
|
@@ -57,6 +57,10 @@ export function createConversationAgent(deps) {
|
|
|
57
57
|
ncbi.pubmed,
|
|
58
58
|
// Verification of one caller-supplied citation (distinct from discovery).
|
|
59
59
|
createResolveCitationTool(citationResolver),
|
|
60
|
+
// Literature outside PubMed. A question about a method, a model or a
|
|
61
|
+
// preprint has no MEDLINE record, thus PubMed alone cannot answer it.
|
|
62
|
+
createSearchSemanticScholarTool({ ...(bioKeys.semanticScholar === undefined ? {} : { apiKey: bioKeys.semanticScholar }) }),
|
|
63
|
+
searchArxivTool,
|
|
60
64
|
// ChEMBL (compounds / drug / mechanism / bioactivity / targets behind one action).
|
|
61
65
|
chemblTool,
|
|
62
66
|
// PubChem (compound / crossrefs / assays behind one action).
|
|
@@ -95,6 +99,7 @@ export function createConversationAgent(deps) {
|
|
|
95
99
|
pool,
|
|
96
100
|
resourcePolicy,
|
|
97
101
|
usageRecorder,
|
|
102
|
+
bioKeys,
|
|
98
103
|
...(refStorePath ? { refStorePath } : {}),
|
|
99
104
|
...(packagesFile ? { packagesFile } : {}),
|
|
100
105
|
...(deps.logger ? { logger: deps.logger } : {}),
|
|
@@ -123,8 +128,6 @@ export function createConversationAgent(deps) {
|
|
|
123
128
|
showUserTool,
|
|
124
129
|
createShowPlanTool(pool),
|
|
125
130
|
showFileTool,
|
|
126
|
-
// Batch literature/biology research (sub-agent as a loop-driving tool).
|
|
127
|
-
createLiteratureReviewerTool({ provider, model, bioKeys, citationResolver, usageRecorder }),
|
|
128
131
|
// Cross-domain analogy generation (sub-agent as a loop-driving tool).
|
|
129
132
|
createGenerateAnalogyReportTool({ provider, model, bioKeys, usageRecorder }),
|
|
130
133
|
// Workspace semantic search + raw read/grep over the read seam.
|
|
@@ -35,7 +35,7 @@ export const REPORT_SESSION_AGENT_ID = "report-session";
|
|
|
35
35
|
* look, record — drives more small tool calls than a conversation turn, thus it
|
|
36
36
|
* gets the headroom of the report runner (REPORT_AGENT_MAX_STEPS).
|
|
37
37
|
*/
|
|
38
|
-
const REPORT_SESSION_MAX_ITERATIONS =
|
|
38
|
+
const REPORT_SESSION_MAX_ITERATIONS = 200;
|
|
39
39
|
/** Build the report `AgentDefinition` with every tool bound to its deps. */
|
|
40
40
|
export function createReportSessionAgent(deps) {
|
|
41
41
|
const { model, pool, embedding, workspaceFs, gateway, resolveWorkspaceRoot, store, threads, chrome, eyes, makeResolver, resolvePageAsset, logger } = deps;
|
|
@@ -15,7 +15,6 @@ export const meta = {
|
|
|
15
15
|
// differently. Declared rather than bolted on, so the resolved roster stays
|
|
16
16
|
// `meta.tools` plus the always-on set.
|
|
17
17
|
tools: [...BASE_SANDBOX_TOOLS, "scanInputs"],
|
|
18
|
-
defaultMaxSteps: 85,
|
|
19
18
|
plannable: false,
|
|
20
19
|
};
|
|
21
20
|
export function createDataProfilerAgent(deps) {
|
|
@@ -26,7 +26,9 @@ export const meta = {
|
|
|
26
26
|
// `single-cell` carries the scirpy reference, which is the route from 10x
|
|
27
27
|
// VDJ / AIRR files to called clonotypes — the input every repertoire metric
|
|
28
28
|
// in `immune-profiling` assumes it already has.
|
|
29
|
-
|
|
29
|
+
// `statistical-modeling` carries the survival-cutpoint correction and the
|
|
30
|
+
// multiplicity rules that the immune-clinical correlation work demands.
|
|
31
|
+
skills: ["immune-profiling", "single-cell", "statistical-modeling", "shared/omics-general"],
|
|
30
32
|
tools: [...BASE_SANDBOX_TOOLS, "pubmed", "searchGene", "lookupAnnotation", "searchInteractions", "searchGeoDatasets", "opentargets"],
|
|
31
33
|
};
|
|
32
34
|
export function createImmuneProfilingAgent(deps) {
|
|
@@ -9,7 +9,6 @@ export const meta = {
|
|
|
9
9
|
suitableFor: ["expression-matrices", "correlation-matrices", "general-omics"],
|
|
10
10
|
skills: ["network-regulatory", "shared/omics-general"],
|
|
11
11
|
tools: [...BASE_SANDBOX_TOOLS, "pubmed", "searchGene", "lookupAnnotation", "searchInteractions"],
|
|
12
|
-
defaultMaxSteps: 35,
|
|
13
12
|
};
|
|
14
13
|
export function createNetworkAgent(deps) {
|
|
15
14
|
return createSandboxAgent(deps, meta, networkAgentPrompt);
|
|
@@ -46,7 +46,7 @@ export type ResourcePolicy = z.infer<typeof ResourcePolicySchema>;
|
|
|
46
46
|
/** Default LLM-turn budget for a sandbox agent step. Covers simple,
|
|
47
47
|
* standard, and complex analyses — extra headroom on simple steps is
|
|
48
48
|
* cheaper than truncating complex ones. */
|
|
49
|
-
export declare const DEFAULT_SANDBOX_MAX_STEPS =
|
|
49
|
+
export declare const DEFAULT_SANDBOX_MAX_STEPS = 200;
|
|
50
50
|
export declare class ResourceLimitsConfigError extends Error {
|
|
51
51
|
constructor(message: string);
|
|
52
52
|
}
|
|
@@ -33,7 +33,7 @@ export const ResourcePolicySchema = z.object({
|
|
|
33
33
|
/** Default LLM-turn budget for a sandbox agent step. Covers simple,
|
|
34
34
|
* standard, and complex analyses — extra headroom on simple steps is
|
|
35
35
|
* cheaper than truncating complex ones. */
|
|
36
|
-
export const DEFAULT_SANDBOX_MAX_STEPS =
|
|
36
|
+
export const DEFAULT_SANDBOX_MAX_STEPS = 200;
|
|
37
37
|
// ── Error ───────────────────────────────────────────────────────────
|
|
38
38
|
export class ResourceLimitsConfigError extends Error {
|
|
39
39
|
constructor(message) {
|
|
@@ -305,9 +305,9 @@ export declare const StepBlockedPartSchema: z.ZodObject<{
|
|
|
305
305
|
export declare const RunCompletedFindingSchema: z.ZodObject<{
|
|
306
306
|
title: z.ZodString;
|
|
307
307
|
confidence: z.ZodEnum<{
|
|
308
|
-
high: "high";
|
|
309
|
-
medium: "medium";
|
|
310
308
|
low: "low";
|
|
309
|
+
medium: "medium";
|
|
310
|
+
high: "high";
|
|
311
311
|
}>;
|
|
312
312
|
}, z.core.$strip>;
|
|
313
313
|
export declare const RunCompletedPartSchema: z.ZodObject<{
|
|
@@ -323,9 +323,9 @@ export declare const RunCompletedPartSchema: z.ZodObject<{
|
|
|
323
323
|
findings: z.ZodArray<z.ZodObject<{
|
|
324
324
|
title: z.ZodString;
|
|
325
325
|
confidence: z.ZodEnum<{
|
|
326
|
-
high: "high";
|
|
327
|
-
medium: "medium";
|
|
328
326
|
low: "low";
|
|
327
|
+
medium: "medium";
|
|
328
|
+
high: "high";
|
|
329
329
|
}>;
|
|
330
330
|
}, z.core.$strip>>;
|
|
331
331
|
note: z.ZodOptional<z.ZodString>;
|
|
@@ -342,9 +342,9 @@ export declare const SynthesizedFindingSchema: z.ZodObject<{
|
|
|
342
342
|
title: z.ZodString;
|
|
343
343
|
description: z.ZodString;
|
|
344
344
|
confidence: z.ZodEnum<{
|
|
345
|
-
high: "high";
|
|
346
|
-
medium: "medium";
|
|
347
345
|
low: "low";
|
|
346
|
+
medium: "medium";
|
|
347
|
+
high: "high";
|
|
348
348
|
}>;
|
|
349
349
|
noveltyStatus: z.ZodEnum<{
|
|
350
350
|
expected: "expected";
|
|
@@ -374,9 +374,9 @@ export declare const RunSynthesisPartSchema: z.ZodObject<{
|
|
|
374
374
|
title: z.ZodString;
|
|
375
375
|
description: z.ZodString;
|
|
376
376
|
confidence: z.ZodEnum<{
|
|
377
|
-
high: "high";
|
|
378
|
-
medium: "medium";
|
|
379
377
|
low: "low";
|
|
378
|
+
medium: "medium";
|
|
379
|
+
high: "high";
|
|
380
380
|
}>;
|
|
381
381
|
noveltyStatus: z.ZodEnum<{
|
|
382
382
|
expected: "expected";
|
|
@@ -647,9 +647,9 @@ export declare const CortexChatPartSchema: z.ZodDiscriminatedUnion<[z.ZodObject<
|
|
|
647
647
|
title: z.ZodString;
|
|
648
648
|
description: z.ZodString;
|
|
649
649
|
confidence: z.ZodEnum<{
|
|
650
|
-
high: "high";
|
|
651
|
-
medium: "medium";
|
|
652
650
|
low: "low";
|
|
651
|
+
medium: "medium";
|
|
652
|
+
high: "high";
|
|
653
653
|
}>;
|
|
654
654
|
noveltyStatus: z.ZodEnum<{
|
|
655
655
|
expected: "expected";
|
|
@@ -707,9 +707,9 @@ export declare const CortexChatPartSchema: z.ZodDiscriminatedUnion<[z.ZodObject<
|
|
|
707
707
|
findings: z.ZodArray<z.ZodObject<{
|
|
708
708
|
title: z.ZodString;
|
|
709
709
|
confidence: z.ZodEnum<{
|
|
710
|
-
high: "high";
|
|
711
|
-
medium: "medium";
|
|
712
710
|
low: "low";
|
|
711
|
+
medium: "medium";
|
|
712
|
+
high: "high";
|
|
713
713
|
}>;
|
|
714
714
|
}, z.core.$strip>>;
|
|
715
715
|
note: z.ZodOptional<z.ZodString>;
|
|
@@ -8,8 +8,8 @@
|
|
|
8
8
|
import { z } from "zod";
|
|
9
9
|
export declare const SEVERITIES: readonly ["high", "medium", "low"];
|
|
10
10
|
export declare const SeveritySchema: z.ZodEnum<{
|
|
11
|
-
high: "high";
|
|
12
|
-
medium: "medium";
|
|
13
11
|
low: "low";
|
|
12
|
+
medium: "medium";
|
|
13
|
+
high: "high";
|
|
14
14
|
}>;
|
|
15
15
|
export type Severity = (typeof SEVERITIES)[number];
|
|
@@ -611,9 +611,9 @@ export declare const ClinicalTrialRowSchema: z.ZodObject<{
|
|
|
611
611
|
start_date: z.ZodNullable<z.ZodString>;
|
|
612
612
|
completion_date: z.ZodNullable<z.ZodString>;
|
|
613
613
|
match_confidence: z.ZodEnum<{
|
|
614
|
-
high: "high";
|
|
615
|
-
medium: "medium";
|
|
616
614
|
low: "low";
|
|
615
|
+
medium: "medium";
|
|
616
|
+
high: "high";
|
|
617
617
|
off_target: "off_target";
|
|
618
618
|
}>;
|
|
619
619
|
attribution: z.ZodObject<{
|
|
@@ -821,9 +821,9 @@ export declare const ClinicalDevelopmentSchema: z.ZodObject<{
|
|
|
821
821
|
start_date: z.ZodNullable<z.ZodString>;
|
|
822
822
|
completion_date: z.ZodNullable<z.ZodString>;
|
|
823
823
|
match_confidence: z.ZodEnum<{
|
|
824
|
-
high: "high";
|
|
825
|
-
medium: "medium";
|
|
826
824
|
low: "low";
|
|
825
|
+
medium: "medium";
|
|
826
|
+
high: "high";
|
|
827
827
|
off_target: "off_target";
|
|
828
828
|
}>;
|
|
829
829
|
attribution: z.ZodObject<{
|
|
@@ -878,9 +878,9 @@ export declare const ClinicalDevelopmentSchema: z.ZodObject<{
|
|
|
878
878
|
start_date: z.ZodNullable<z.ZodString>;
|
|
879
879
|
completion_date: z.ZodNullable<z.ZodString>;
|
|
880
880
|
match_confidence: z.ZodEnum<{
|
|
881
|
-
high: "high";
|
|
882
|
-
medium: "medium";
|
|
883
881
|
low: "low";
|
|
882
|
+
medium: "medium";
|
|
883
|
+
high: "high";
|
|
884
884
|
off_target: "off_target";
|
|
885
885
|
}>;
|
|
886
886
|
attribution: z.ZodObject<{
|
|
@@ -1231,9 +1231,9 @@ export declare const OrganRiskRowSchema: z.ZodObject<{
|
|
|
1231
1231
|
oncology: "oncology";
|
|
1232
1232
|
}>;
|
|
1233
1233
|
risk_level: z.ZodEnum<{
|
|
1234
|
-
high: "high";
|
|
1235
|
-
medium: "medium";
|
|
1236
1234
|
low: "low";
|
|
1235
|
+
medium: "medium";
|
|
1236
|
+
high: "high";
|
|
1237
1237
|
}>;
|
|
1238
1238
|
signal_type_count: z.ZodNumber;
|
|
1239
1239
|
signals: z.ZodObject<{
|
|
@@ -1759,9 +1759,9 @@ export declare const SafetyFlagSchema: z.ZodObject<{
|
|
|
1759
1759
|
trail: z.ZodString;
|
|
1760
1760
|
mechanism_hypothesis: z.ZodOptional<z.ZodNullable<z.ZodString>>;
|
|
1761
1761
|
severity: z.ZodEnum<{
|
|
1762
|
-
high: "high";
|
|
1763
|
-
medium: "medium";
|
|
1764
1762
|
low: "low";
|
|
1763
|
+
medium: "medium";
|
|
1764
|
+
high: "high";
|
|
1765
1765
|
}>;
|
|
1766
1766
|
support: z.ZodDiscriminatedUnion<[z.ZodObject<{
|
|
1767
1767
|
state: z.ZodLiteral<"scored">;
|
|
@@ -2008,9 +2008,9 @@ export declare const SafetyProfileSchema: z.ZodObject<{
|
|
|
2008
2008
|
oncology: "oncology";
|
|
2009
2009
|
}>;
|
|
2010
2010
|
risk_level: z.ZodEnum<{
|
|
2011
|
-
high: "high";
|
|
2012
|
-
medium: "medium";
|
|
2013
2011
|
low: "low";
|
|
2012
|
+
medium: "medium";
|
|
2013
|
+
high: "high";
|
|
2014
2014
|
}>;
|
|
2015
2015
|
signal_type_count: z.ZodNumber;
|
|
2016
2016
|
signals: z.ZodObject<{
|
|
@@ -2562,9 +2562,9 @@ export declare const SafetyProfileSchema: z.ZodObject<{
|
|
|
2562
2562
|
trail: z.ZodString;
|
|
2563
2563
|
mechanism_hypothesis: z.ZodOptional<z.ZodNullable<z.ZodString>>;
|
|
2564
2564
|
severity: z.ZodEnum<{
|
|
2565
|
-
high: "high";
|
|
2566
|
-
medium: "medium";
|
|
2567
2565
|
low: "low";
|
|
2566
|
+
medium: "medium";
|
|
2567
|
+
high: "high";
|
|
2568
2568
|
}>;
|
|
2569
2569
|
support: z.ZodDiscriminatedUnion<[z.ZodObject<{
|
|
2570
2570
|
state: z.ZodLiteral<"scored">;
|
|
@@ -4112,11 +4112,11 @@ export declare const ExpressionHeatmapCellSchema: z.ZodObject<{
|
|
|
4112
4112
|
dog: "dog";
|
|
4113
4113
|
}>;
|
|
4114
4114
|
rank: z.ZodEnum<{
|
|
4115
|
+
low: "low";
|
|
4116
|
+
medium: "medium";
|
|
4117
|
+
high: "high";
|
|
4115
4118
|
no_data: "no_data";
|
|
4116
4119
|
absent: "absent";
|
|
4117
|
-
high: "high";
|
|
4118
|
-
medium: "medium";
|
|
4119
|
-
low: "low";
|
|
4120
4120
|
not_loaded: "not_loaded";
|
|
4121
4121
|
}>;
|
|
4122
4122
|
}, z.core.$strip>;
|
|
@@ -4131,11 +4131,11 @@ export declare const ExpressionHeatmapSchema: z.ZodObject<{
|
|
|
4131
4131
|
dog: "dog";
|
|
4132
4132
|
}>;
|
|
4133
4133
|
rank: z.ZodEnum<{
|
|
4134
|
+
low: "low";
|
|
4135
|
+
medium: "medium";
|
|
4136
|
+
high: "high";
|
|
4134
4137
|
no_data: "no_data";
|
|
4135
4138
|
absent: "absent";
|
|
4136
|
-
high: "high";
|
|
4137
|
-
medium: "medium";
|
|
4138
|
-
low: "low";
|
|
4139
4139
|
not_loaded: "not_loaded";
|
|
4140
4140
|
}>;
|
|
4141
4141
|
}, z.core.$strip>>;
|
|
@@ -4267,11 +4267,11 @@ export declare const PreclinicalProfileSchema: z.ZodObject<{
|
|
|
4267
4267
|
dog: "dog";
|
|
4268
4268
|
}>;
|
|
4269
4269
|
rank: z.ZodEnum<{
|
|
4270
|
+
low: "low";
|
|
4271
|
+
medium: "medium";
|
|
4272
|
+
high: "high";
|
|
4270
4273
|
no_data: "no_data";
|
|
4271
4274
|
absent: "absent";
|
|
4272
|
-
high: "high";
|
|
4273
|
-
medium: "medium";
|
|
4274
|
-
low: "low";
|
|
4275
4275
|
not_loaded: "not_loaded";
|
|
4276
4276
|
}>;
|
|
4277
4277
|
}, z.core.$strip>>;
|
|
@@ -4631,9 +4631,9 @@ export declare const DiscoveryTrialRowSchema: z.ZodObject<{
|
|
|
4631
4631
|
start_date: z.ZodOptional<z.ZodString>;
|
|
4632
4632
|
completion_date: z.ZodOptional<z.ZodString>;
|
|
4633
4633
|
match_confidence: z.ZodEnum<{
|
|
4634
|
-
high: "high";
|
|
4635
|
-
medium: "medium";
|
|
4636
4634
|
low: "low";
|
|
4635
|
+
medium: "medium";
|
|
4636
|
+
high: "high";
|
|
4637
4637
|
}>;
|
|
4638
4638
|
relevance_basis: z.ZodDiscriminatedUnion<[z.ZodObject<{
|
|
4639
4639
|
kind: z.ZodLiteral<"drug_in_class_match">;
|
|
@@ -4703,9 +4703,9 @@ export declare const DiscoveryTrialsSchema: z.ZodDiscriminatedUnion<[z.ZodObject
|
|
|
4703
4703
|
start_date: z.ZodOptional<z.ZodString>;
|
|
4704
4704
|
completion_date: z.ZodOptional<z.ZodString>;
|
|
4705
4705
|
match_confidence: z.ZodEnum<{
|
|
4706
|
-
high: "high";
|
|
4707
|
-
medium: "medium";
|
|
4708
4706
|
low: "low";
|
|
4707
|
+
medium: "medium";
|
|
4708
|
+
high: "high";
|
|
4709
4709
|
}>;
|
|
4710
4710
|
relevance_basis: z.ZodDiscriminatedUnion<[z.ZodObject<{
|
|
4711
4711
|
kind: z.ZodLiteral<"drug_in_class_match">;
|
|
@@ -4772,9 +4772,9 @@ export declare const DiscoveryTrialsSchema: z.ZodDiscriminatedUnion<[z.ZodObject
|
|
|
4772
4772
|
start_date: z.ZodOptional<z.ZodString>;
|
|
4773
4773
|
completion_date: z.ZodOptional<z.ZodString>;
|
|
4774
4774
|
match_confidence: z.ZodEnum<{
|
|
4775
|
-
high: "high";
|
|
4776
|
-
medium: "medium";
|
|
4777
4775
|
low: "low";
|
|
4776
|
+
medium: "medium";
|
|
4777
|
+
high: "high";
|
|
4778
4778
|
}>;
|
|
4779
4779
|
relevance_basis: z.ZodDiscriminatedUnion<[z.ZodObject<{
|
|
4780
4780
|
kind: z.ZodLiteral<"drug_in_class_match">;
|
|
@@ -4861,9 +4861,9 @@ export declare const ExecutiveRecommendationDataSchema: z.ZodObject<{
|
|
|
4861
4861
|
insufficient_evidence: "insufficient_evidence";
|
|
4862
4862
|
}>;
|
|
4863
4863
|
confidence: z.ZodEnum<{
|
|
4864
|
-
high: "high";
|
|
4865
|
-
medium: "medium";
|
|
4866
4864
|
low: "low";
|
|
4865
|
+
medium: "medium";
|
|
4866
|
+
high: "high";
|
|
4867
4867
|
}>;
|
|
4868
4868
|
rationale: z.ZodString;
|
|
4869
4869
|
key_strengths: z.ZodDefault<z.ZodArray<z.ZodString>>;
|
|
@@ -4899,9 +4899,9 @@ export declare const ExecutiveRecommendationSchema: z.ZodDiscriminatedUnion<[z.Z
|
|
|
4899
4899
|
insufficient_evidence: "insufficient_evidence";
|
|
4900
4900
|
}>;
|
|
4901
4901
|
confidence: z.ZodEnum<{
|
|
4902
|
-
high: "high";
|
|
4903
|
-
medium: "medium";
|
|
4904
4902
|
low: "low";
|
|
4903
|
+
medium: "medium";
|
|
4904
|
+
high: "high";
|
|
4905
4905
|
}>;
|
|
4906
4906
|
rationale: z.ZodString;
|
|
4907
4907
|
key_strengths: z.ZodDefault<z.ZodArray<z.ZodString>>;
|
|
@@ -5713,11 +5713,11 @@ export declare const ReferenceBiologyShape: z.ZodObject<{
|
|
|
5713
5713
|
dog: "dog";
|
|
5714
5714
|
}>;
|
|
5715
5715
|
rank: z.ZodEnum<{
|
|
5716
|
+
low: "low";
|
|
5717
|
+
medium: "medium";
|
|
5718
|
+
high: "high";
|
|
5716
5719
|
no_data: "no_data";
|
|
5717
5720
|
absent: "absent";
|
|
5718
|
-
high: "high";
|
|
5719
|
-
medium: "medium";
|
|
5720
|
-
low: "low";
|
|
5721
5721
|
not_loaded: "not_loaded";
|
|
5722
5722
|
}>;
|
|
5723
5723
|
}, z.core.$strip>>;
|
|
@@ -6231,9 +6231,9 @@ export declare const DossierSchema: z.ZodObject<{
|
|
|
6231
6231
|
start_date: z.ZodNullable<z.ZodString>;
|
|
6232
6232
|
completion_date: z.ZodNullable<z.ZodString>;
|
|
6233
6233
|
match_confidence: z.ZodEnum<{
|
|
6234
|
-
high: "high";
|
|
6235
|
-
medium: "medium";
|
|
6236
6234
|
low: "low";
|
|
6235
|
+
medium: "medium";
|
|
6236
|
+
high: "high";
|
|
6237
6237
|
off_target: "off_target";
|
|
6238
6238
|
}>;
|
|
6239
6239
|
attribution: z.ZodObject<{
|
|
@@ -6288,9 +6288,9 @@ export declare const DossierSchema: z.ZodObject<{
|
|
|
6288
6288
|
start_date: z.ZodNullable<z.ZodString>;
|
|
6289
6289
|
completion_date: z.ZodNullable<z.ZodString>;
|
|
6290
6290
|
match_confidence: z.ZodEnum<{
|
|
6291
|
-
high: "high";
|
|
6292
|
-
medium: "medium";
|
|
6293
6291
|
low: "low";
|
|
6292
|
+
medium: "medium";
|
|
6293
|
+
high: "high";
|
|
6294
6294
|
off_target: "off_target";
|
|
6295
6295
|
}>;
|
|
6296
6296
|
attribution: z.ZodObject<{
|
|
@@ -6644,9 +6644,9 @@ export declare const DossierSchema: z.ZodObject<{
|
|
|
6644
6644
|
oncology: "oncology";
|
|
6645
6645
|
}>;
|
|
6646
6646
|
risk_level: z.ZodEnum<{
|
|
6647
|
-
high: "high";
|
|
6648
|
-
medium: "medium";
|
|
6649
6647
|
low: "low";
|
|
6648
|
+
medium: "medium";
|
|
6649
|
+
high: "high";
|
|
6650
6650
|
}>;
|
|
6651
6651
|
signal_type_count: z.ZodNumber;
|
|
6652
6652
|
signals: z.ZodObject<{
|
|
@@ -7198,9 +7198,9 @@ export declare const DossierSchema: z.ZodObject<{
|
|
|
7198
7198
|
trail: z.ZodString;
|
|
7199
7199
|
mechanism_hypothesis: z.ZodOptional<z.ZodNullable<z.ZodString>>;
|
|
7200
7200
|
severity: z.ZodEnum<{
|
|
7201
|
-
high: "high";
|
|
7202
|
-
medium: "medium";
|
|
7203
7201
|
low: "low";
|
|
7202
|
+
medium: "medium";
|
|
7203
|
+
high: "high";
|
|
7204
7204
|
}>;
|
|
7205
7205
|
support: z.ZodDiscriminatedUnion<[z.ZodObject<{
|
|
7206
7206
|
state: z.ZodLiteral<"scored">;
|
|
@@ -8417,11 +8417,11 @@ export declare const DossierSchema: z.ZodObject<{
|
|
|
8417
8417
|
dog: "dog";
|
|
8418
8418
|
}>;
|
|
8419
8419
|
rank: z.ZodEnum<{
|
|
8420
|
+
low: "low";
|
|
8421
|
+
medium: "medium";
|
|
8422
|
+
high: "high";
|
|
8420
8423
|
no_data: "no_data";
|
|
8421
8424
|
absent: "absent";
|
|
8422
|
-
high: "high";
|
|
8423
|
-
medium: "medium";
|
|
8424
|
-
low: "low";
|
|
8425
8425
|
not_loaded: "not_loaded";
|
|
8426
8426
|
}>;
|
|
8427
8427
|
}, z.core.$strip>>;
|
|
@@ -8755,9 +8755,9 @@ export declare const DossierSchema: z.ZodObject<{
|
|
|
8755
8755
|
start_date: z.ZodOptional<z.ZodString>;
|
|
8756
8756
|
completion_date: z.ZodOptional<z.ZodString>;
|
|
8757
8757
|
match_confidence: z.ZodEnum<{
|
|
8758
|
-
high: "high";
|
|
8759
|
-
medium: "medium";
|
|
8760
8758
|
low: "low";
|
|
8759
|
+
medium: "medium";
|
|
8760
|
+
high: "high";
|
|
8761
8761
|
}>;
|
|
8762
8762
|
relevance_basis: z.ZodDiscriminatedUnion<[z.ZodObject<{
|
|
8763
8763
|
kind: z.ZodLiteral<"drug_in_class_match">;
|
|
@@ -8824,9 +8824,9 @@ export declare const DossierSchema: z.ZodObject<{
|
|
|
8824
8824
|
start_date: z.ZodOptional<z.ZodString>;
|
|
8825
8825
|
completion_date: z.ZodOptional<z.ZodString>;
|
|
8826
8826
|
match_confidence: z.ZodEnum<{
|
|
8827
|
-
high: "high";
|
|
8828
|
-
medium: "medium";
|
|
8829
8827
|
low: "low";
|
|
8828
|
+
medium: "medium";
|
|
8829
|
+
high: "high";
|
|
8830
8830
|
}>;
|
|
8831
8831
|
relevance_basis: z.ZodDiscriminatedUnion<[z.ZodObject<{
|
|
8832
8832
|
kind: z.ZodLiteral<"drug_in_class_match">;
|
|
@@ -9077,9 +9077,9 @@ export declare const DossierSchema: z.ZodObject<{
|
|
|
9077
9077
|
insufficient_evidence: "insufficient_evidence";
|
|
9078
9078
|
}>;
|
|
9079
9079
|
confidence: z.ZodEnum<{
|
|
9080
|
-
high: "high";
|
|
9081
|
-
medium: "medium";
|
|
9082
9080
|
low: "low";
|
|
9081
|
+
medium: "medium";
|
|
9082
|
+
high: "high";
|
|
9083
9083
|
}>;
|
|
9084
9084
|
rationale: z.ZodString;
|
|
9085
9085
|
key_strengths: z.ZodDefault<z.ZodArray<z.ZodString>>;
|
|
@@ -9660,9 +9660,9 @@ export declare const DossierBodySchema: z.ZodObject<{
|
|
|
9660
9660
|
start_date: z.ZodNullable<z.ZodString>;
|
|
9661
9661
|
completion_date: z.ZodNullable<z.ZodString>;
|
|
9662
9662
|
match_confidence: z.ZodEnum<{
|
|
9663
|
-
high: "high";
|
|
9664
|
-
medium: "medium";
|
|
9665
9663
|
low: "low";
|
|
9664
|
+
medium: "medium";
|
|
9665
|
+
high: "high";
|
|
9666
9666
|
off_target: "off_target";
|
|
9667
9667
|
}>;
|
|
9668
9668
|
attribution: z.ZodObject<{
|
|
@@ -9717,9 +9717,9 @@ export declare const DossierBodySchema: z.ZodObject<{
|
|
|
9717
9717
|
start_date: z.ZodNullable<z.ZodString>;
|
|
9718
9718
|
completion_date: z.ZodNullable<z.ZodString>;
|
|
9719
9719
|
match_confidence: z.ZodEnum<{
|
|
9720
|
-
high: "high";
|
|
9721
|
-
medium: "medium";
|
|
9722
9720
|
low: "low";
|
|
9721
|
+
medium: "medium";
|
|
9722
|
+
high: "high";
|
|
9723
9723
|
off_target: "off_target";
|
|
9724
9724
|
}>;
|
|
9725
9725
|
attribution: z.ZodObject<{
|
|
@@ -10073,9 +10073,9 @@ export declare const DossierBodySchema: z.ZodObject<{
|
|
|
10073
10073
|
oncology: "oncology";
|
|
10074
10074
|
}>;
|
|
10075
10075
|
risk_level: z.ZodEnum<{
|
|
10076
|
-
high: "high";
|
|
10077
|
-
medium: "medium";
|
|
10078
10076
|
low: "low";
|
|
10077
|
+
medium: "medium";
|
|
10078
|
+
high: "high";
|
|
10079
10079
|
}>;
|
|
10080
10080
|
signal_type_count: z.ZodNumber;
|
|
10081
10081
|
signals: z.ZodObject<{
|
|
@@ -10627,9 +10627,9 @@ export declare const DossierBodySchema: z.ZodObject<{
|
|
|
10627
10627
|
trail: z.ZodString;
|
|
10628
10628
|
mechanism_hypothesis: z.ZodOptional<z.ZodNullable<z.ZodString>>;
|
|
10629
10629
|
severity: z.ZodEnum<{
|
|
10630
|
-
high: "high";
|
|
10631
|
-
medium: "medium";
|
|
10632
10630
|
low: "low";
|
|
10631
|
+
medium: "medium";
|
|
10632
|
+
high: "high";
|
|
10633
10633
|
}>;
|
|
10634
10634
|
support: z.ZodDiscriminatedUnion<[z.ZodObject<{
|
|
10635
10635
|
state: z.ZodLiteral<"scored">;
|
|
@@ -11680,11 +11680,11 @@ export declare const DossierBodySchema: z.ZodObject<{
|
|
|
11680
11680
|
dog: "dog";
|
|
11681
11681
|
}>;
|
|
11682
11682
|
rank: z.ZodEnum<{
|
|
11683
|
+
low: "low";
|
|
11684
|
+
medium: "medium";
|
|
11685
|
+
high: "high";
|
|
11683
11686
|
no_data: "no_data";
|
|
11684
11687
|
absent: "absent";
|
|
11685
|
-
high: "high";
|
|
11686
|
-
medium: "medium";
|
|
11687
|
-
low: "low";
|
|
11688
11688
|
not_loaded: "not_loaded";
|
|
11689
11689
|
}>;
|
|
11690
11690
|
}, z.core.$strip>>;
|
|
@@ -12018,9 +12018,9 @@ export declare const DossierBodySchema: z.ZodObject<{
|
|
|
12018
12018
|
start_date: z.ZodOptional<z.ZodString>;
|
|
12019
12019
|
completion_date: z.ZodOptional<z.ZodString>;
|
|
12020
12020
|
match_confidence: z.ZodEnum<{
|
|
12021
|
-
high: "high";
|
|
12022
|
-
medium: "medium";
|
|
12023
12021
|
low: "low";
|
|
12022
|
+
medium: "medium";
|
|
12023
|
+
high: "high";
|
|
12024
12024
|
}>;
|
|
12025
12025
|
relevance_basis: z.ZodDiscriminatedUnion<[z.ZodObject<{
|
|
12026
12026
|
kind: z.ZodLiteral<"drug_in_class_match">;
|
|
@@ -12087,9 +12087,9 @@ export declare const DossierBodySchema: z.ZodObject<{
|
|
|
12087
12087
|
start_date: z.ZodOptional<z.ZodString>;
|
|
12088
12088
|
completion_date: z.ZodOptional<z.ZodString>;
|
|
12089
12089
|
match_confidence: z.ZodEnum<{
|
|
12090
|
-
high: "high";
|
|
12091
|
-
medium: "medium";
|
|
12092
12090
|
low: "low";
|
|
12091
|
+
medium: "medium";
|
|
12092
|
+
high: "high";
|
|
12093
12093
|
}>;
|
|
12094
12094
|
relevance_basis: z.ZodDiscriminatedUnion<[z.ZodObject<{
|
|
12095
12095
|
kind: z.ZodLiteral<"drug_in_class_match">;
|
|
@@ -12340,9 +12340,9 @@ export declare const DossierBodySchema: z.ZodObject<{
|
|
|
12340
12340
|
insufficient_evidence: "insufficient_evidence";
|
|
12341
12341
|
}>;
|
|
12342
12342
|
confidence: z.ZodEnum<{
|
|
12343
|
-
high: "high";
|
|
12344
|
-
medium: "medium";
|
|
12345
12343
|
low: "low";
|
|
12344
|
+
medium: "medium";
|
|
12345
|
+
high: "high";
|
|
12346
12346
|
}>;
|
|
12347
12347
|
rationale: z.ZodString;
|
|
12348
12348
|
key_strengths: z.ZodDefault<z.ZodArray<z.ZodString>>;
|
|
@@ -29,9 +29,9 @@ export declare const SafetyTargetSchema: z.ZodObject<{
|
|
|
29
29
|
}>;
|
|
30
30
|
clinical_consequence: z.ZodString;
|
|
31
31
|
severity: z.ZodEnum<{
|
|
32
|
-
high: "high";
|
|
33
|
-
medium: "medium";
|
|
34
32
|
low: "low";
|
|
33
|
+
medium: "medium";
|
|
34
|
+
high: "high";
|
|
35
35
|
}>;
|
|
36
36
|
references: z.ZodArray<z.ZodString>;
|
|
37
37
|
}, z.core.$strip>;
|
|
@@ -68,9 +68,9 @@ export declare const SafetyPanelFileSchema: z.ZodObject<{
|
|
|
68
68
|
}>;
|
|
69
69
|
clinical_consequence: z.ZodString;
|
|
70
70
|
severity: z.ZodEnum<{
|
|
71
|
-
high: "high";
|
|
72
|
-
medium: "medium";
|
|
73
71
|
low: "low";
|
|
72
|
+
medium: "medium";
|
|
73
|
+
high: "high";
|
|
74
74
|
}>;
|
|
75
75
|
references: z.ZodArray<z.ZodString>;
|
|
76
76
|
}, z.core.$strip>>;
|
package/dist/index.d.ts
CHANGED
|
@@ -67,8 +67,9 @@ export { createConfiguredAiSdkProvider, DEFAULT_MAX_OUTPUT_TOKENS } from "./prov
|
|
|
67
67
|
export type { AiSdkProviderConfig, ConfiguredAiSdkProviderDeps } from "./providers/ai-sdk.js";
|
|
68
68
|
export { createEmbeddingProvider } from "./providers/embedding.js";
|
|
69
69
|
export type { EmbeddingProviderDeps } from "./providers/embedding.js";
|
|
70
|
-
export type { AgentChat, ChatProvider, EmbeddingProvider, ChatRequest, ChatResponse, ChatStreamEvent, ChatUsage, ModelMessage, PromptCachePolicy, } from "./providers/types.js";
|
|
70
|
+
export type { AgentChat, ChatProvider, EmbeddingProvider, ChatRequest, ChatResponse, ChatStreamEvent, ChatUsage, ModelMessage, PromptCachePolicy, ReasoningPolicy, } from "./providers/types.js";
|
|
71
71
|
export { DEFAULT_PROMPT_CACHE, promptCacheProviderOptions } from "./providers/prompt-cache.js";
|
|
72
|
+
export { DEFAULT_REASONING } from "./providers/reasoning.js";
|
|
72
73
|
export { toProviderError, isProviderError } from "./providers/errors.js";
|
|
73
74
|
export type { ProviderError } from "./providers/errors.js";
|
|
74
75
|
export { createStreamingChat } from "./providers/streaming-chat.js";
|
package/dist/index.js
CHANGED
|
@@ -104,6 +104,15 @@ export { createEmbeddingProvider } from "./providers/embedding.js";
|
|
|
104
104
|
// `"off"`; the `cortex.harness.agent.cache_*_tokens` metrics show which case a
|
|
105
105
|
// deployment is actually in.
|
|
106
106
|
export { DEFAULT_PROMPT_CACHE, promptCacheProviderOptions } from "./providers/prompt-cache.js";
|
|
107
|
+
// Reasoning depth. `ReasoningPolicy` is the vendor-neutral name for how deep a
|
|
108
|
+
// model reasons; a composition root sets it per run through
|
|
109
|
+
// `RunAgentOptions.reasoning`. It defaults to `DEFAULT_REASONING` — `xhigh` —
|
|
110
|
+
// because an agent loop drives tools over many iterations, and a shallow turn
|
|
111
|
+
// there wastes more calls than the deeper turn costs in tokens. The provider
|
|
112
|
+
// package resolves the name for the model that it is bound to, thus a model
|
|
113
|
+
// that accepts no `xhigh` gets the nearest name that it accepts. A host on a
|
|
114
|
+
// model with no reasoning support passes `"provider-default"`.
|
|
115
|
+
export { DEFAULT_REASONING } from "./providers/reasoning.js";
|
|
107
116
|
// Provider error channel. `ProviderError` is the value `chat`/`embed` fail
|
|
108
117
|
// with; `toProviderError` is its sole constructor. Exposed so an embedder
|
|
109
118
|
// realizing its own `ChatProvider`/`EmbeddingProvider` fails with the exact
|