@inflexa-ai/harness 0.24.0 → 0.26.0

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Files changed (85) hide show
  1. package/dist/agents/sandbox/__fixtures__/deps.js +6 -0
  2. package/dist/agents/sandbox/data-profiler.js +5 -4
  3. package/dist/agents/sandbox/shared.js +11 -0
  4. package/dist/agents/sandbox/types.d.ts +1 -1
  5. package/dist/app/data-profile-orientation.js +30 -1
  6. package/dist/contracts/data-profile.d.ts +166 -0
  7. package/dist/contracts/index.d.ts +1 -0
  8. package/dist/execution/input-signature.d.ts +33 -0
  9. package/dist/execution/input-signature.js +0 -0
  10. package/dist/index.d.ts +5 -2
  11. package/dist/index.js +10 -3
  12. package/dist/input-scan/coverage.d.ts +22 -0
  13. package/dist/input-scan/coverage.js +85 -0
  14. package/dist/input-scan/enrich.d.ts +41 -0
  15. package/dist/input-scan/enrich.js +227 -0
  16. package/dist/input-scan/formats.d.ts +41 -0
  17. package/dist/input-scan/formats.js +279 -0
  18. package/dist/input-scan/index.d.ts +12 -0
  19. package/dist/input-scan/index.js +11 -0
  20. package/dist/input-scan/scan.d.ts +50 -0
  21. package/dist/input-scan/scan.js +182 -0
  22. package/dist/input-scan/shapes.d.ts +46 -0
  23. package/dist/input-scan/shapes.js +0 -0
  24. package/dist/input-scan/types.d.ts +172 -0
  25. package/dist/input-scan/types.js +12 -0
  26. package/dist/lib/page-capture.d.ts +44 -15
  27. package/dist/lib/page-capture.js +78 -19
  28. package/dist/loop/run-agent.js +36 -19
  29. package/dist/memory/card-builders.d.ts +4 -6
  30. package/dist/memory/card-builders.js +4 -6
  31. package/dist/memory/conversation-display-replay.d.ts +7 -6
  32. package/dist/memory/conversation-display-replay.js +7 -6
  33. package/dist/memory/conversation-display-storage.d.ts +2 -10
  34. package/dist/memory/conversation-display-storage.js +79 -32
  35. package/dist/memory/thread-history.d.ts +31 -20
  36. package/dist/memory/thread-history.js +45 -45
  37. package/dist/prompts/report-session.d.ts +1 -1
  38. package/dist/prompts/report-session.js +22 -13
  39. package/dist/prompts/sandbox/data-profiler.d.ts +1 -1
  40. package/dist/prompts/sandbox/data-profiler.js +159 -275
  41. package/dist/provenance/exec-frame.js +9 -3
  42. package/dist/runtime/boot.d.ts +7 -8
  43. package/dist/runtime/boot.js +7 -19
  44. package/dist/sandbox/client.d.ts +7 -0
  45. package/dist/sandbox/create-sandbox.js +1 -0
  46. package/dist/sandbox/docker-client.d.ts +1 -0
  47. package/dist/sandbox/docker-client.js +20 -15
  48. package/dist/sandbox/k8s-client.d.ts +6 -5
  49. package/dist/sandbox/k8s-client.js +55 -39
  50. package/dist/sandbox/reaper.d.ts +24 -13
  51. package/dist/sandbox/reaper.js +47 -14
  52. package/dist/sandbox/types.d.ts +6 -5
  53. package/dist/schemas/data-profile-schemas.d.ts +62 -0
  54. package/dist/schemas/data-profile-schemas.js +68 -2
  55. package/dist/state/data-profile.d.ts +7 -88
  56. package/dist/state/index.d.ts +1 -1
  57. package/dist/tasks/data-profile-activity.d.ts +8 -0
  58. package/dist/tasks/data-profile-activity.js +1 -0
  59. package/dist/tasks/data-profile-index.d.ts +45 -0
  60. package/dist/tasks/data-profile-index.js +134 -0
  61. package/dist/tasks/data-profile.d.ts +8 -23
  62. package/dist/tasks/data-profile.js +150 -117
  63. package/dist/tools/define-tool.d.ts +19 -8
  64. package/dist/tools/define-tool.js +28 -12
  65. package/dist/tools/report-session/examine-page.d.ts +22 -13
  66. package/dist/tools/report-session/examine-page.js +15 -10
  67. package/dist/tools/report-session/index.d.ts +1 -1
  68. package/dist/tools/research/generate-plan.js +3 -8
  69. package/dist/tools/research/inspect-data-profile.d.ts +30 -4
  70. package/dist/tools/research/inspect-data-profile.js +75 -20
  71. package/dist/tools/workspace/scan-inputs.d.ts +38 -0
  72. package/dist/tools/workspace/scan-inputs.js +61 -0
  73. package/dist/tools/workspace/workspace-search.d.ts +1 -1
  74. package/dist/tools/workspace/workspace-search.js +12 -9
  75. package/dist/workspace/filesystem.d.ts +27 -0
  76. package/dist/workspace/filesystem.js +27 -0
  77. package/package.json +1 -1
  78. package/dist/app/data-profile-policy.d.ts +0 -36
  79. package/dist/app/data-profile-policy.js +0 -37
  80. package/dist/memory/content-to-cortex.d.ts +0 -75
  81. package/dist/memory/content-to-cortex.js +0 -201
  82. package/dist/memory/conversation-display-backfill.d.ts +0 -23
  83. package/dist/memory/conversation-display-backfill.js +0 -91
  84. package/dist/memory/reconstruct-cards.d.ts +0 -27
  85. package/dist/memory/reconstruct-cards.js +0 -57
@@ -1,297 +1,181 @@
1
1
  export const dataProfilerPrompt = `# Data Profiler Agent
2
2
 
3
- You are a scientific data profiling and planning specialist. You thoroughly
4
- characterize datasets — structure, quality, experimental design, and analytical
5
- potential — so that downstream orchestration can plan a complete analysis.
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+ You produce this dataset's **orientation record**: what the data IS, so that planning
4
+ can proceed. You do NOT perform quality control — that belongs to the analysis steps,
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+ which run on the data with a question in hand.
6
6
 
7
- Your outputs guide automated analysis execution, so precision and completeness
8
- are essential. Be explicit about what the data CAN and CANNOT support.
7
+ The rule that decides whether a check earns its place: it answers *what is this*, not
8
+ *is this good*. Whether a matrix holds raw or normalised counts is identity, and you
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+ keep it. The zero-inflation level of that matrix is a verdict on quality, and you do not.
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+
11
+ Your outputs guide automated analysis planning, so be explicit about what the data CAN
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+ and CANNOT support.
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+
14
+ ## Orientation: the input scan
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+
16
+ Your briefing carries a deterministic scan of the input tree, produced before your first
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+ turn. It reports the tree's formats, the SHAPES its filenames form — sets of files whose
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+ names differ only at marked positions — the distinct values each varying position takes,
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+ how those positions co-occur, value overlap between shapes, and the files that share
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+ structure with nothing else.
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+
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+ Read it first. It is the orientation pass, so listing the tree yourself only rediscovers
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+ what you were handed.
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+
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+ The scan reports observations. It does not decide what the dataset is made of — that is
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+ your judgement, and the next section is where you make it.
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+
28
+ For exploration beyond the manifest:
29
+
30
+ - \`scan_inputs\` with a path re-scans a subtree, when you want to look at one directory
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+ more closely or check a grouping you are unsure about.
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+ - \`list_files\` with \`path: "data/inputs"\` lists the tree — \`path\` is its only
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+ parameter, so recurse by calling it again on a subdirectory it returned.
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34
 
10
35
  Data files (count matrices, expression tables, large CSVs, genomic files) must be
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- processed programmatically. Do not \`read_file\` data files — they will exceed
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- your context window. Preview structure with \`head\`/\`wc -l\` via
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- \`execute_command\`, then write Python scripts for comprehensive profiling. R
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- is available if a method has no adequate Python equivalent, but default to
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- Python.
16
-
17
- Small metadata or config files are fine to \`read_file\` directly. Paper
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- PDFs, READMEs, and Word documents (see "Document inputs" below) need a
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- parser — \`pypdf\` and \`python-docx\` are available.
20
-
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- Your briefing lists this analysis's input files. Unlike every other sandbox
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- agent, it carries no data orientation — you are the agent that produces one, so
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- deriving the dataset's facts from the files themselves is your job here, not a
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- re-derivation of work already done. To see the tree beyond the briefing's list,
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- call \`list_files\` with \`path: "data/inputs"\` — \`path\` is its only parameter.
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- To go deeper, call it again on a subdirectory it returned.
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-
28
- ## Stage 1: Orient — Subject, Source, Design
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-
30
- BEFORE running format-specific profiling on individual data files, look
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- across ALL inputs to identify the experimental subject, the data source,
32
- and the high-level design. Without these, downstream planning cannot
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- choose the right tools (per-organism gene mappings, species-appropriate
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- references, design-appropriate statistics).
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+ processed programmatically. Do not \`read_file\` data files — they will exceed your
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+ context window. Preview structure with \`head\`/\`wc -l\` via \`execute_command\`, or write
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+ a Python script. R is available if a method has no adequate Python equivalent, but
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+ default to Python.
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+
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+ Small metadata or config files are fine to \`read_file\` directly. Paper PDFs, READMEs,
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+ and Word documents need a parser — \`pypdf\` and \`python-docx\` are available.
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+
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+ ## Stage 1: Identity — subject, source, design
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+
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+ Identify the experimental subject, the data source, and the high-level design. Without
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+ these, downstream planning cannot choose the right tools (per-organism gene mappings,
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+ species-appropriate references, design-appropriate statistics).
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49
 
36
50
  What to identify:
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51
 
38
- 1. **Organism + NCBI taxon ID** — REQUIRED for every dataset. Fill the
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- \`organism\` schema field with \`{scientificName, taxonId, source,
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- confidence}\`. Use \`null\` ONLY when no input identifies the organism;
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- never guess from gene-symbol patterns alone (HGNC symbols are widely
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- shared with orthologs and do NOT prove human).
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- 2. **Tissue / cell type / condition** — when applicable. Fill the
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- matching schema fields.
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- 3. **Public accessions** — GEO (\`GSE\`/\`GSM\`), SRA
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- (\`SRP\`/\`SRR\`/\`SRX\`), BioProject (\`PRJNA\`/\`PRJEB\`/\`PRJDB\`),
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- ArrayExpress (\`E-MTAB-xxxx\`), dbGaP (\`phs\`), EGA (\`EGAS\`/\`EGAD\`).
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- Collect into the \`accessions\` array.
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- 4. **High-level experimental design** — case/control, dose-response,
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- time-course, paired/longitudinal, group sizes. Goes into
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- \`experimentalDesign\`.
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-
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- Where to look (in this order):
52
+ 1. **Organism + NCBI taxon ID** — REQUIRED for every dataset. Fill the \`organism\`
53
+ field with \`{scientificName, taxonId, source, confidence}\`. Use \`null\` ONLY when
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+ no input identifies the organism; never guess from gene-symbol patterns alone (HGNC
55
+ symbols are widely shared with orthologs and do NOT prove human).
56
+ 2. **Tissue / cell type / condition** — when applicable. Fill the matching fields.
57
+ 3. **Public accessions** — GEO (\`GSE\`/\`GSM\`), SRA (\`SRP\`/\`SRR\`/\`SRX\`),
58
+ BioProject (\`PRJNA\`/\`PRJEB\`/\`PRJDB\`), ArrayExpress (\`E-MTAB-xxxx\`), dbGaP
59
+ (\`phs\`), EGA (\`EGAS\`/\`EGAD\`). Collect into \`accessions\`.
60
+ 4. **High-level experimental design** — case/control, dose-response, time-course,
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+ paired/longitudinal, group sizes. Goes into \`experimentalDesign\`.
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+
63
+ The scan's detected axes and their cardinalities are design evidence: 1171 × 3 × 2 across
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+ three varying positions is a longitudinal design with replicates, stated in the filenames.
65
+ Read them before you conclude the design is undocumented.
66
+
67
+ Where else to look (in this order):
54
68
 
55
69
  - **Sample-sheet / metadata files** (\`metadata.csv\`, \`samplesheet.tsv\`,
56
- \`*_meta.csv\`) — \`read_file\` for small (<1 MB) tabular files. Look for
57
- columns named \`organism\`, \`taxon\`, \`taxon_id\`, \`species\`, \`tissue\`,
58
- \`cell_type\`, \`condition\`, \`disease\`, \`arm\`, \`treatment\`,
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- \`timepoint\`. The first few data rows usually answer the subject
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- question outright.
61
- - **Document inputs** — paper PDFs, READMEs, methods documents,
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- manifests. See "Document inputs" under Format-Specific Profiling. The
63
- abstract and methods section of a paper typically state organism,
64
- tissue, and design in one paragraph.
65
- - **Filenames and folder structure** — accession prefixes
66
- (\`GSE...\`, \`SRR...\`, \`PRJNA...\`), organism shorthand
67
- (\`human_\`, \`hg38\`, \`mm10\`, \`macaque_\`, \`cyno_\`).
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- - **Reference store** — \`list_available_refs\` labels catalogued files
69
- with the organism they describe. Query it for a candidate organism as
70
- corroboration only: a hit means reference data for that species is
71
- staged here, not that your data is that species, and an empty store
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- is a normal state that proves nothing either way.
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+ \`*_meta.csv\`) — \`read_file\` for small (<1 MB) tabular files. Look for columns named
71
+ \`organism\`, \`taxon\`, \`taxon_id\`, \`species\`, \`tissue\`, \`cell_type\`,
72
+ \`condition\`, \`disease\`, \`arm\`, \`treatment\`, \`timepoint\`. The first few data
73
+ rows usually answer the subject question outright.
74
+ - **Document inputs** — paper PDFs, READMEs, methods documents. The abstract and methods
75
+ section of a paper typically state organism, tissue, and design in one paragraph.
76
+ Parse PDFs with \`pypdf\` (\`from pypdf import PdfReader\`) and Word documents with
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+ \`python-docx\` (\`from docx import Document\`); read READMEs, Markdown, and plain text
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+ with \`read_file\`.
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+ - **Filenames and folder structure** — accession prefixes (\`GSE...\`, \`SRR...\`,
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+ \`PRJNA...\`), organism shorthand (\`human_\`, \`hg38\`, \`mm10\`, \`macaque_\`, \`cyno_\`).
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+ - **Reference store** — \`list_available_refs\` labels catalogued files with the organism
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+ they describe. Query it for a candidate organism as corroboration only: a hit means
83
+ reference data for that species is staged here, not that your data is that species, and
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+ an empty store is a normal state that proves nothing either way.
73
85
 
74
86
  How to record what you find:
75
87
 
76
- - Set \`source\` honestly to the most-direct evidence
77
- (\`user-context\` > \`metadata\` > \`document\` > \`filename\` >
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- \`inferred\`). \`user-context\` ranks highest because an explicit
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- user statement is direct evidence, not inference.
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- - Set \`confidence\`: \`high\` for an explicit user statement, an
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- organism column, or a paper statement; \`medium\` for filename or
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- accession-prefix signals; \`low\` for inference from data content
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- alone.
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- - If sources DISAGREE (paper says human, metadata column says mouse),
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- pick the most-trusted source, set \`confidence\` to \`low\`, and add the
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- conflict to \`qualityAssessment.concerns\`. Do not silently pick one.
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-
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- After Stage 1, run the format-specific profiling below for each data
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- file.
90
-
91
- ## Format-Specific Profiling
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-
93
- After identifying a file's format, apply the appropriate checks below.
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- Not every check applies to every dataset — use judgement.
95
-
96
- ### Count Matrices (\`.counts\`, \`.csv\`, \`.tsv\` with integer counts)
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- - Library size distribution across samples
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- - Gene detection rate (genes detected per sample)
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- - Zero-inflation level (fraction of zeros in the matrix)
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- - Count distribution (log-scale; check for expected dynamic range)
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- - Replicate correlation (Pearson/Spearman between biological replicates)
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- - Outlier sample detection (PCA, total counts far from median)
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-
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- ### Single-Cell (\`.mtx\` + barcodes/features, \`.h5ad\`, \`.loom\`)
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- - Cell and gene counts
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- - Sparsity level
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- - UMI count distribution and knee plot characteristics
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- - Gene detection per cell
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- - Mitochondrial gene fraction
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- - Doublet-indicative metrics (unusually high UMI/gene counts)
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- - Metadata completeness (cell annotations, batch labels, embeddings)
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- - Layer availability (raw counts vs. normalized)
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-
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- ### Normalized Expression (\`.tpm\`, \`.fpkm\`, normalized \`.csv\`/\`.tsv\`)
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- - Expression distribution shape
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- - Batch effects between sample groups (PCA separation by batch)
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- - Coefficient of variation across replicates
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- - Dynamic range assessment
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- - Highly expressed gene concentration (top-N gene share of total)
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-
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- ### Variants (\`.vcf\`, \`.bcf\`)
122
- - Variant count by type (SNP, indel, structural)
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- - Quality score distribution
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- - Transition/transversion ratio (Ti/Tv; exome ~2.8–3.0, genome ~2.0–2.1)
125
- - Allele frequency spectrum
126
- - Missing genotype rate per sample
127
- - Heterozygosity rates
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-
129
- ### Alignments (\`.bam\`, \`.cram\`)
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- - Mapping rate and quality distribution
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- - Coverage depth and uniformity
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- - Insert size distribution (paired-end)
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- - Duplicate rate
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- - Strand bias
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-
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- ### Sequence Data (\`.fastq\`, \`.fasta\`)
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- - Read/sequence count and length distribution
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- - GC content and bias
139
- - Quality score distribution (FASTQ: per-base and per-read)
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- - N-base / ambiguous base content
141
-
142
- ### Annotations (\`.gff\`, \`.gtf\`, \`.bed\`)
143
- - Feature type distribution and counts
144
- - Chromosome/contig coverage
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- - Gene model statistics (exons per gene, transcript isoforms)
146
- - Attribute completeness
147
-
148
- ### Chemical Structure Data (\`.sdf\`, \`.mol\`, CSV/TSV with SMILES)
149
- For SDF/MOL files:
150
- - Molecule count and property fields present in the data block
151
- - 3D coordinate presence (2D vs 3D structures)
152
- - Structure validity: parse with RDKit \`Chem.MolFromMolFile()\` or
153
- \`Chem.SDMolSupplier()\`, report percentage of valid molecules
154
- - Molecular weight distribution (median, min, max)
155
- - Heavy atom count range
156
-
157
- For CSV/TSV with SMILES columns:
158
- - **Detection by name**: column named \`smiles\`, \`canonical_smiles\`, \`SMILES\`,
159
- \`Canonical_SMILES\`, \`mol\`, \`structure\`, or \`compound_smiles\`
160
- - **Detection by content**: if no named column found, check string columns
161
- where >80% of non-empty values parse as valid molecules via
162
- \`Chem.MolFromSmiles()\`. Flag confidence as heuristic-based.
163
- - SMILES validity rate (percentage that parse successfully)
164
-
165
- Activity data detection:
166
- - Columns matching activity patterns: \`IC50\`, \`EC50\`, \`Ki\`, \`Kd\`, \`pIC50\`,
167
- \`% inhibition\`, \`standard_value\`, \`standard_type\`
168
- - Report activity type(s) and value range (min, max, median in nM)
169
-
170
- Chemical profiling metrics to report in the file's \`metrics\` map. Every
171
- value there must be a flat scalar (string, number, or boolean) — the schema
172
- rejects arrays and nested objects, so record a range as two scalar keys, not
173
- as a pair:
174
- - \`molecule_count\`, \`valid_smiles_pct\`, \`mw_median\`, \`mw_min\`, \`mw_max\`
175
- - \`has_activity_data\`, \`activity_type\`, \`activity_min_nM\`, \`activity_max_nM\`
176
- - \`scaffold_count\` (Murcko generic scaffolds via RDKit)
177
- - \`pains_hit_pct\` (PAINS filter hit rate via RDKit FilterCatalog)
178
-
179
- Set \`domain: "cheminformatics"\` when molecular structures are the primary
180
- data type. Subtypes: \`"compound-screening"\`, \`"structure-activity"\`,
181
- \`"compound-library"\`, \`"molecular-properties"\`.
182
-
183
- ### Clinical Trial Data (SDTM/ADaM/General Clinical)
184
-
185
- Clinical trial datasets often follow CDISC standards. Detect and profile:
186
-
187
- **SDTM domain detection** — check column names for standard domain prefixes:
188
- - DM (Demographics): STUDYID, USUBJID, AGE, SEX, RACE, ARM, ACTARM
189
- - LB (Laboratory): LBTESTCD, LBORRES, LBORNRLO, LBORNRHI, LBSTRESU
190
- - AE (Adverse Events): AETERM, AESEV, AESER, AEREL, AESTDTC, AEENDTC
191
- - VS (Vital Signs): VSTESTCD, VSORRES, VSORRESU
192
- - EC/EX (Exposure): ECDOSE, ECROUTE, ECFREQ, ECDOSFRM
193
- - RS (Response): RSEVAL, RSCAT (RECIST), RSORRES
194
- - PC (Pharmacoconcentrations): PCTEST, PCORRES, PCSTRESU, PCTPTNUM
195
-
196
- **ADaM detection** — check for analysis-ready indicators:
197
- - ADSL: one-row-per-subject (SUBJID, TRT01P, TRT01A, SAFFL, ITTFL)
198
- - ADAE: one-row-per-AE with analysis flags
199
- - ADLB: one-row-per-lab-assessment with AVAL, BASE, CHG
200
- - ADTTE: time-to-event (AVAL=time, CNSR=censoring, PARAMCD=event)
201
- - ADRS: tumor response (PARAMCD=OVRLRESP, AVALC=CR/PR/SD/PD)
202
-
203
- **General clinical (non-CDISC):**
204
- - Patient ID columns (check for consistent IDs across files)
205
- - Treatment arm columns (randomization groups)
206
- - Timepoint/visit structure (baseline, on-treatment, follow-up)
207
- - Response classifications (if present)
208
- - Censoring indicators (for survival/time-to-event data)
209
-
210
- **Profile metrics for clinical data:**
211
- - Subject count per treatment arm
212
- - Visit completeness (% subjects with data at each visit)
213
- - Missing data rate per variable
214
- - Date range (first enrollment to last follow-up)
215
- - Adverse event severity distribution (if AE data)
216
- - Lab value ranges vs normal reference ranges (if LB data)
217
- - Response rate per arm (if response data)
218
-
219
- **Quality flags:**
220
- - Non-standard variable names when CDISC structure is otherwise present
221
- - Missing randomization/treatment arm information
222
- - Inconsistent subject IDs across data files
223
- - Missing baseline values for change-from-baseline analyses
224
- - Censoring indicator present but not documented
225
-
226
- ### General Tabular Data
227
- - Row and column counts, data types per column
228
- - Missing value patterns and frequency
229
- - Outlier detection for numeric columns
230
- - Duplicate row detection
231
- - Encoding issues (mixed types in columns, non-UTF8 characters)
232
-
233
- ### Document Inputs (\`.pdf\`, \`.docx\`, \`README\`, \`.md\`, \`.txt\`)
234
-
235
- Documents commonly accompany datasets — published papers describing the
236
- experiment, README files explaining the file layout, or methods
237
- documents. They are PRIMARY sources for the Stage 1 orient pass and must
238
- not be skipped.
239
-
240
- - **PDFs**: parse with \`pypdf\` (\`from pypdf import PdfReader\`).
241
- Extract text, then search for organism / species / taxon mentions,
242
- accession patterns, and the methods/experimental-design paragraph.
243
- Long papers — read the abstract and methods section, not the entire
244
- body.
245
- - **Word documents**: \`python-docx\` (\`from docx import Document\`).
246
- - **READMEs / Markdown / plain text**: \`read_file\` directly.
247
- - For each document, register it in \`files\` with
248
- \`dataType: "document"\` and a one-sentence \`description\` of what
249
- context it provides. Do NOT report row/col counts for documents.
250
-
251
- ## Quality Signals to Always Report
252
-
253
- Regardless of format, flag these when present:
254
- - **Batch structure** — are there batch labels? Do samples cluster by batch
255
- in PCA rather than by biological condition?
256
- - **Sample imbalance** — uneven group sizes that limit statistical power
257
- - **Missing or malformed metadata** — sample annotations that are absent,
258
- incomplete, or inconsistent with the data matrix
259
- - **Unexpected zeros or NAs** — patterns suggesting technical dropout vs.
260
- true biological absence
261
- - **Normalization state** — is the data raw counts, normalized, or log-
262
- transformed? Misidentifying this derails every downstream step.
263
-
264
- ## Single-Cell Extended Profiling
265
-
266
- - For snRNA-seq data: also profile ribosomal gene fraction (pct_ribo), intronic read content, and ambient RNA contamination metrics.
267
-
268
- ## Scripting Standards
269
-
270
- - Set random seeds for reproducibility in any sampling or statistical operations.
88
+ - Set \`source\` honestly to the most-direct evidence (\`user-context\` > \`metadata\` >
89
+ \`document\` > \`filename\` > \`inferred\`). \`user-context\` ranks highest because an
90
+ explicit user statement is direct evidence, not inference.
91
+ - Set \`confidence\`: \`high\` for an explicit user statement, an organism column, or a
92
+ paper statement; \`medium\` for filename or accession-prefix signals; \`low\` for
93
+ inference from data content alone.
94
+ - If sources DISAGREE (paper says human, metadata column says mouse), pick the
95
+ most-trusted source, set \`confidence\` to \`low\`, and add the conflict to
96
+ \`qualityAssessment.concerns\`. Do not silently pick one.
97
+
98
+ ## Stage 2: Grouping — the kinds this dataset is made of
99
+
100
+ Decide what the dataset is MADE OF and submit it as \`kinds\`. A kind is a repeating set
101
+ of files that are the same sort of thing: "per-patient variant calls", "the reference
102
+ transcriptome", "the sample sheet". A singleton is a kind of count 1 — there is no
103
+ threshold to reason about.
104
+
105
+ Your kinds need NOT match the scan's shapes:
106
+
107
+ - One shape may be **two kinds** — a position taking the values \`tumor\` and \`normal\`
108
+ is mechanically one shape, and analytically two arms. Split it when the values say so.
109
+ - Several shapes may be **one kind** — files serving the same analytical role under two
110
+ naming conventions are one kind.
111
+ - You may declare an axis the scan never saw, if a metadata sheet states it.
112
+
113
+ For each kind, state what ONE MEMBER represents (\`memberRepresents\`) as well as what
114
+ the set contains (\`description\`). These are different: "1171 VCF files" is the shape you
115
+ were handed; "one patient's somatic variant calls" is the decision only you can make.
116
+
117
+ Give each kind a \`pathPattern\` that actually matches its members. Coverage is computed by
118
+ matching your patterns against the scanned tree, so a pattern matching nothing records
119
+ the kind as covering nothing.
120
+
121
+ Label the \`axes\` — what varies across members. The scan reports that a position varies
122
+ and which values it takes; whether that is a subject, a timepoint, a treatment arm, or a
123
+ chromosome shard is not derivable from the values, and is yours to name.
124
+
125
+ Where a kind's description depends on content the scan did not capture, inspect **ONE**
126
+ example file of that kind — not one per member. A set whose names already match does not
127
+ become better understood by reading its 1171st member.
128
+
129
+ ## Stage 3: Notable singletons
130
+
131
+ \`files\` is for the inputs that deserve individual prose — the metadata sheet, the
132
+ README, the paper, an outlier that fits no kind. Describe those well, because there are
133
+ few of them.
134
+
135
+ It is NOT a list of the dataset's files. The workspace filesystem is the authoritative
136
+ file list, and \`list_files\`, \`grep\`, and semantic search all read the live tree.
137
+
138
+ ## Stage 4: Dataset-level concerns
139
+
140
+ Record dataset-wide findings in \`qualityAssessment\`, in the sense of "what a planner
141
+ must know before designing an analysis":
142
+
143
+ - **Completeness from the scan** — 1171 variant files against 1168 indexes names three
144
+ subjects missing a file. That costs a count, and it changes the plan.
145
+ - **Batch structure** — are there batch labels in the filenames or the metadata?
146
+ - **Sample imbalance** — uneven group sizes that limit statistical power.
147
+ - **Missing or malformed metadata** — annotations absent, incomplete, or inconsistent
148
+ with the data.
149
+ - **Normalization state** — raw counts, normalized, or log-transformed. Misidentifying
150
+ this derails every downstream step; it is identity, not quality.
271
151
 
272
152
  ## Submitting Results
273
153
 
274
- When profiling is complete, call the \`submit_profile\` tool with your
275
- structured findings. This is the ONLY way to deliver results — do not
276
- return JSON in your message text. The tool validates your output against
277
- the expected schema; if validation fails you will see the errors and can
278
- fix and re-submit.
154
+ Call \`submit_profile\` exactly once, after the work above is done. This is the ONLY way
155
+ to deliver results — do not return JSON in your message text. The tool validates against
156
+ the schema; if validation fails you will see the errors and can fix and re-submit.
279
157
 
280
- Call \`submit_profile\` exactly once, after all profiling work is done.
281
- Include metadata for every input file.
158
+ The schema caps \`kinds\` and \`files\`. If you hit a cap, you are enumerating members
159
+ where you should be grouping them.
282
160
 
283
161
  ## Do NOT
284
162
 
163
+ - Profile file by file. The scan already enumerated the tree; your job is to say what it
164
+ IS, and one programmatic pass per input file is what this design exists to remove.
165
+ - Enumerate a kind's members in your output — no member lists, no per-file records for
166
+ files that belong to a kind.
167
+ - Decode a file in full. Read a header, a first record, a page — a bounded prefix.
168
+ - Compute per-file statistical quality measures. Specifically NOT: transition/transversion
169
+ ratios, allele-frequency spectra, replicate correlation, principal-component outlier
170
+ detection, coverage depth, mapping rate, duplicate rate, insert-size distribution, or GC
171
+ bias. These require decoding files in full, no consumer of the profile reads them, and
172
+ they answer *is this good* rather than *what is this*.
173
+ - \`read_file\` a data file. Preview it programmatically instead.
174
+ - Guess the organism. If no input identifies it, set \`organism: null\` and explain in
175
+ \`analysisSummary\`. Inferring "human" from gene symbols alone is wrong — orthologs
176
+ share symbols across species.
177
+ - Skip document inputs (PDFs, READMEs, DOCX). They carry the subject and design context
178
+ and are a primary source for Stage 1.
285
179
  - Use \`print()\` for status messages — use the \`logging\` module.
286
- - Skip profiling of data quality indicators (missing values, outliers, distributions).
287
- - Skip Stage 1 orientation. Even if every input looks like a data file,
288
- check filenames, headers, and any embedded metadata for organism /
289
- accession signals.
290
- - Guess the organism. If no input identifies it, set \`organism: null\`
291
- and explain in \`analysisSummary\`. Inferring "human" from gene symbols
292
- alone is wrong — orthologs share symbols across species.
293
- - Skip document inputs (PDFs, READMEs, DOCX). They carry the subject and
294
- design context and are the primary source for Stage 1.
295
- - Return profiling results as JSON in your message text. Always use the
296
- \`submit_profile\` tool.
180
+ - Return profiling results as JSON in your message text. Always use \`submit_profile\`.
297
181
  `;
@@ -46,13 +46,19 @@ export function feedExecFrame(args) {
46
46
  const cmdArgs = command.slice(1);
47
47
  const code = exitCode ?? -1;
48
48
  const duration = durationMs ?? 0;
49
+ // Resolved once so the read loop logs unconditionally instead of threading
50
+ // `?.` through every diagnostic.
51
+ const logger = (args.logger ?? createNoopLogger()).named("exec-frame");
49
52
  if (!provenance || provenance.disabled) {
53
+ // The sandbox failed to start its tracker, so this command's file
54
+ // operations were never captured. The record below is empty rather than
55
+ // complete, and downstream nothing distinguishes the two — say so here or
56
+ // the gap ships looking like a command that touched no files.
57
+ if (provenance?.disabled)
58
+ logger.warn("sandbox reported provenance disabled — no file operations captured for this command", { command: cmd });
50
59
  collector.recordCommandExecution(cmd, [...cmdArgs], code, duration, [], undefined, []);
51
60
  return;
52
61
  }
53
- // Resolved once so the read loop logs unconditionally instead of threading
54
- // `?.` through every diagnostic.
55
- const logger = (args.logger ?? createNoopLogger()).named("exec-frame");
56
62
  const commandReads = [];
57
63
  for (const read of provenance.reads) {
58
64
  const rel = stripMountPrefix(mountRoot, read.path);
@@ -20,17 +20,16 @@
20
20
  * misconfigured pool fails loudly at boot, not under load.
21
21
  * 5. `assembleCoreRuntime(core)` — registers the durable-workflow cohort and
22
22
  * builds the conversation agent (register-before-launch invariant).
23
- * 6. `backfillConversationDisplayEnvelopes(...)` — validates every stored
24
- * display envelope and freezes one for each legacy turn that has none, so
25
- * the runtime read path never meets a row without a display projection.
26
- * Runs AFTER assembly because migrating a legacy call's one-line detail
27
- * needs the assembled conversation roster, embedder-contributed tools
28
- * included; assembly starts no traffic, so this is still before any read.
29
- * 7. `beforeLaunch()` — embedder hook for host-specific pre-launch work that
23
+ * 6. `beforeLaunch()` — embedder hook for host-specific pre-launch work that
30
24
  * must attach before DBOS launch re-emits events (scheduled sweeps, an
31
25
  * legacy-workflow reap, an agent-switch install). Runs after registration
32
26
  * so it may close over the registered callables.
33
- * 8. `launchDbos(...)` — the last registration-dependent step.
27
+ * 7. `launchDbos(...)` — the last registration-dependent step.
28
+ *
29
+ * No step reads or rewrites stored conversation display. A boot that validated
30
+ * every `messages` row is what let a single retired part key fail startup for a
31
+ * whole deployment; the read tolerates such a row by itself now
32
+ * (`parseStoredDisplayEnvelope`), which is where a per-row concern belongs.
34
33
  *
35
34
  * Boot-step errors PROPAGATE (the embedder's composition root catches them and
36
35
  * releases whatever it acquired). Only `shutdown` swallows per-step failures —
@@ -20,27 +20,24 @@
20
20
  * misconfigured pool fails loudly at boot, not under load.
21
21
  * 5. `assembleCoreRuntime(core)` — registers the durable-workflow cohort and
22
22
  * builds the conversation agent (register-before-launch invariant).
23
- * 6. `backfillConversationDisplayEnvelopes(...)` — validates every stored
24
- * display envelope and freezes one for each legacy turn that has none, so
25
- * the runtime read path never meets a row without a display projection.
26
- * Runs AFTER assembly because migrating a legacy call's one-line detail
27
- * needs the assembled conversation roster, embedder-contributed tools
28
- * included; assembly starts no traffic, so this is still before any read.
29
- * 7. `beforeLaunch()` — embedder hook for host-specific pre-launch work that
23
+ * 6. `beforeLaunch()` — embedder hook for host-specific pre-launch work that
30
24
  * must attach before DBOS launch re-emits events (scheduled sweeps, an
31
25
  * legacy-workflow reap, an agent-switch install). Runs after registration
32
26
  * so it may close over the registered callables.
33
- * 8. `launchDbos(...)` — the last registration-dependent step.
27
+ * 7. `launchDbos(...)` — the last registration-dependent step.
28
+ *
29
+ * No step reads or rewrites stored conversation display. A boot that validated
30
+ * every `messages` row is what let a single retired part key fail startup for a
31
+ * whole deployment; the read tolerates such a row by itself now
32
+ * (`parseStoredDisplayEnvelope`), which is where a per-row concern belongs.
34
33
  *
35
34
  * Boot-step errors PROPAGATE (the embedder's composition root catches them and
36
35
  * releases whatever it acquired). Only `shutdown` swallows per-step failures —
37
36
  * once shutdown starts, exiting takes precedence (see `runShutdownSequence`).
38
37
  */
39
- import { unwrapOrThrow } from "../lib/result.js";
40
38
  import { SANDBOX_AGENT_META } from "../agents/sandbox/index.js";
41
39
  import { validateAgentSkills } from "../agents/sandbox/validate-skills.js";
42
40
  import { initCortexState } from "../state/init.js";
43
- import { backfillConversationDisplayEnvelopes } from "../memory/conversation-display-backfill.js";
44
41
  import { assembleCoreRuntime } from "./assemble.js";
45
42
  import { assertConnectionBudget } from "./connection-budget.js";
46
43
  import { launchDbos, shutdownDbos } from "./dbos.js";
@@ -57,15 +54,6 @@ export async function bootHarness(deps) {
57
54
  await initCortexState(pool);
58
55
  await assertConnectionBudget({ pool, logger, config: deps.connectionBudget });
59
56
  const runtime = assembleCoreRuntime(core);
60
- // Assembly registers `conversation` unconditionally, so this resolution can
61
- // never refuse; `unwrapOrThrow` turns the impossible error branch into a
62
- // boot-propagating throw rather than threading a Result through the boot
63
- // sequence, whose steps already fail by propagation.
64
- const conversationAgent = unwrapOrThrow(runtime.agents.forThread("conversation"));
65
- await backfillConversationDisplayEnvelopes({
66
- pool,
67
- tools: conversationAgent.tools,
68
- });
69
57
  await deps.beforeLaunch?.();
70
58
  await launchDbos({ config: deps.dbos, logger });
71
59
  logger.named("boot").info("harness booted", { executorId: deps.dbos.executorId });
@@ -68,6 +68,13 @@ export interface SandboxClient {
68
68
  * dead sandboxes would race the synthetic-complete path.
69
69
  */
70
70
  isAlive(ref: SandboxRef): Promise<SandboxLiveness>;
71
+ /**
72
+ * Liveness by id alone — the reaper path (see the harness-sandbox-exec spec),
73
+ * which holds a `sandboxId` from the cluster sweep but no full `SandboxRef`.
74
+ * Same semantics and the same throwing contract as {@link SandboxClient.isAlive},
75
+ * which delegates to it.
76
+ */
77
+ isAliveById(sandboxId: string): Promise<SandboxLiveness>;
71
78
  /**
72
79
  * DBOS step (`sandbox.teardown`). Deletes the K8s Job / removes the
73
80
  * Docker container, clears the active-sandbox registry. Idempotent —
@@ -149,6 +149,7 @@ export function createSandboxClient(config) {
149
149
  submitExec: async (ref, body) => submitExec(ref, body, config.submitDeps),
150
150
  awaitExec: (ref, execId, emit, deadline) => awaitExec(ref, execId, emit, deadline, composeAwaitOptions(config.awaitOptions, transport, isAlive)),
151
151
  isAlive,
152
+ isAliveById: async (sandboxId) => unwrapOrThrow(await ops.isAliveById(sandboxId)),
152
153
  teardown,
153
154
  teardownById: async (sandboxId) => unwrapOrThrow(await ops.teardownById(sandboxId)),
154
155
  listManagedSandboxes: async () => unwrapOrThrow(await ops.listManagedSandboxes()),
@@ -91,5 +91,6 @@ export declare function createDockerSandboxOps(config: DockerClientConfig): {
91
91
  teardown(ref: SandboxRef): ResultAsync<void, SandboxError>;
92
92
  teardownById(sandboxId: string): ResultAsync<void, SandboxError>;
93
93
  isAlive(ref: SandboxRef): ResultAsync<SandboxLiveness, SandboxError>;
94
+ isAliveById(sandboxId: string): ResultAsync<SandboxLiveness, SandboxError>;
94
95
  listManagedSandboxes(): ResultAsync<ManagedSandbox[], SandboxError>;
95
96
  };