@gmod/cram 7.0.0 → 7.0.1

package/dist/cram-bundle.js

@@ -1,2 +1,2 @@
 /*! For license information please see cram-bundle.js.LICENSE.txt */
-(()=>{var A={6:function(A,t,r){"use strict";var e=this&&this.__importDefault||function(A){return A&&A.__esModule?A:{default:A}};Object.defineProperty(t,"__esModule",{value:!0});const v=e(r(141)),n=r(272),j=r(761);class f extends v.default{decode(A,t,r,e){const{blockContentId:v}=this.parameters,j=r[v];if(!j)throw new n.CramMalformedError(`no block found with content ID ${v}`);const f=e.externalBlocks.getCursor(v);return this._decodeByteArray(j,f)}_decodeByteArray(A,t){const r=A.content,{stopByte:e}=this.parameters,v=t.bytePosition;let n=t.bytePosition;for(;r[n]!==e&&n<r.length;){if(n===r.length)throw new j.CramBufferOverrunError("byteArrayStop reading beyond length of data buffer?");n+=1}return t.bytePosition=n+1,r.subarray(v,n)}}t.default=f},11:(A,t)=>{"use strict";Object.defineProperty(t,"__esModule",{value:!0}),t.parseHeaderText=function(A){const t=A.split(/\r?\n/),r=[];for(const A of t){const[t,...e]=A.split(/\t/);t&&r.push({tag:t.slice(1),data:e.map(A=>{const 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t=0;t<this.parameters.numCodes;t++)A[t]={symbol:this.parameters.symbols[t],bitLength:this.parameters.bitLengths[t]};A=A.sort((A,t)=>A.bitLength-t.bitLength||A.symbol-t.symbol),this.codeBook={},A.forEach(A=>{this.codeBook[A.bitLength]||(this.codeBook[A.bitLength]=[]),this.codeBook[A.bitLength].push(A.symbol)})}buildCodes(){this.codes={};let A=0,t=-1;Object.entries(this.codeBook).forEach(([r,e])=>{const v=Number.parseInt(r,10);e.forEach(r=>{const e={bitLength:v,value:r,bitCode:0};t+=1;const n=v-A;if(t<<=n,e.bitCode=t,A+=n,function(A){let t=A-(A>>1)&1431655765;return t=(858993459&t)+(t>>2&858993459),16843009*(t+(t>>4)&252645135)>>24}(t)>v)throw new j.CramMalformedError("Symbol out of range");this.codes[r]=e})})}buildCaches(){this.sortedCodes=Object.values(this.codes).sort((A,t)=>A.bitLength-t.bitLength||A.bitCode-t.bitCode),this.sortedValuesByBitCode=this.sortedCodes.map(A=>A.value),this.sortedBitCodes=this.sortedCodes.map(A=>A.bitCode),this.sortedBitLengthsByBitCode=this.sortedCodes.map(A=>A.bitLength);const A=Math.max(...this.sortedBitCodes);this.bitCodeToValue=new Array(A+1).fill(-1);for(let A=0;A<this.sortedBitCodes.length;A+=1)this.bitCodeToValue[this.sortedCodes[A].bitCode]=A}decode(A,t,r,e){return this._decode(A,t,e.coreBlock)}_decodeZeroLengthCode(){return this.sortedCodes[0].value}_decode(A,t,r){const e=t.content;let v=0,f=0;for(let A=0;A<this.sortedCodes.length;A+=1){const t=this.sortedCodes[A].bitLength;f<<=t-v,f|=(0,n.getBits)(e,r,t-v),v=t;{const r=this.bitCodeToValue[f];if(r>-1&&this.sortedBitLengthsByBitCode[r]===t)return this.sortedValuesByBitCode[r];for(let r=A;this.sortedCodes[r+1].bitLength===t&&r<this.sortedCodes.length;r+=1)A+=1}}throw new j.CramMalformedError("Huffman symbol not found.")}}t.default=f},64:(A,t)=>{"use strict";Object.defineProperty(t,"__esModule",{value:!0}),t.default=class{constructor(A){this.blob=A}async read(A,t=0){if(!A)return new Uint8Array(0);const r=t,e=r+A,v=this.blob.slice(r,e);return v.bytes?v.bytes():new Uint8Array(await v.arrayBuffer())}async readFile(A){const t="string"==typeof A?A:A?.encoding;if("utf8"===t)return this.blob.text();if(t)throw new Error(`unsupported encoding: ${t}`);return this.blob.bytes?this.blob.bytes():new Uint8Array(await this.blob.arrayBuffer())}async stat(){return{size:this.blob.size}}async close(){}}},86:(A,t,r)=>{const e=r(308).A;A.exports=e,A.exports.default=e},141:(A,t)=>{"use strict";Object.defineProperty(t,"__esModule",{value:!0}),t.default=class{constructor(A,t){this.parameters=A,this.dataType=t}}},151:A=>{var t={utf8:{stringToBytes:function(A){return t.bin.stringToBytes(unescape(encodeURIComponent(A)))},bytesToString:function(A){return 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0===e.lengthOnRef?e.alignmentStart>=t&&e.alignmentStart<=r:e.alignmentStart<=r&&e.alignmentStart+e.lengthOnRef-1>t))));let s=Array.prototype.concat(...f);if(e.viewAsPairs){const A={},t={};for(const r of s){const e=r.readName;if(void 0===e)throw new Error("readName undefined");const v=r.uniqueId;A[e]||(A[e]=0),A[e]+=1,t[v]=1}const r={};Object.entries(A).forEach(([A,t])=>{1===t&&(r[A]=!0)});const n=[];for(const A of s){const t=A.readName;if(void 0===t)throw new Error("readName undefined");if(r[t]&&A.mate&&(A.mate.sequenceId===v||e.pairAcrossChr)&&Math.abs(A.alignmentStart-A.mate.alignmentStart)<e.maxInsertSize){const t=this.index.getEntriesForRange(A.mate.sequenceId,A.mate.alignmentStart,A.mate.alignmentStart+1);n.push(t)}}const j=await Promise.all(n);let f=[];for(const A of j)f.push(...A);f=f.sort((A,t)=>A.toString().localeCompare(t.toString())).filter((A,t,r)=>!t||A.toString()!==r[t-1].toString());const b=[],o=[];for(const A of f){let 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A&&A.__esModule?A:{default:A}};Object.defineProperty(t,"__esModule",{value:!0}),t.MateFlagsDecoder=t.CramFlagsDecoder=t.BamFlagsDecoder=t.MateFlags=t.CramFlags=t.BamFlags=void 0;const v=e(r(588)),n={a:0,A:0,c:1,C:1,g:2,G:2,t:3,T:3,n:4,N:4};function j(A){const t={};for(const[r,e]of A)t[`is${e}`]=A=>!!(A&r),t[`set${e}`]=A=>A|r;return t}t.BamFlags=[[1,"Paired"],[2,"ProperlyPaired"],[4,"SegmentUnmapped"],[8,"MateUnmapped"],[16,"ReverseComplemented"],[32,"MateReverseComplemented"],[64,"Read1"],[128,"Read2"],[256,"Secondary"],[512,"FailedQc"],[1024,"Duplicate"],[2048,"Supplementary"]],t.CramFlags=[[1,"PreservingQualityScores"],[2,"Detached"],[4,"WithMateDownstream"],[8,"DecodeSequenceAsStar"]],t.MateFlags=[[1,"OnNegativeStrand"],[2,"Unmapped"]],t.BamFlagsDecoder=j(t.BamFlags),t.CramFlagsDecoder=j(t.CramFlags),t.MateFlagsDecoder=j(t.MateFlags),t.default=class{constructor({flags:A,cramFlags:t,readLength:r,mappingQuality:e,lengthOnRef:v,qualityScores:n,mateRecordNumber:j,readBases:f,readFeatures:s,mateToUse:b,readGroupId:o,readName:i,sequenceId:a,uniqueId:g,templateSize:I,alignmentStart:c,tags:E}){this.flags=A,this.cramFlags=t,this.readLength=r,this.mappingQuality=e,this.lengthOnRef=v,this.qualityScores=n,f&&(this.readBases=f),this.readGroupId=o,this.readName=i,this.sequenceId=a,this.uniqueId=g,this.templateSize=I,this.alignmentStart=c,this.tags=E,s&&(this.readFeatures=s),b&&(this.mate={flags:b.mateFlags,readName:b.mateReadName,sequenceId:b.mateSequenceId,alignmentStart:b.mateAlignmentStart}),j&&(this.mateRecordNumber=j)}isPaired(){return!!(this.flags&v.default.BAM_FPAIRED)}isProperlyPaired(){return!!(this.flags&v.default.BAM_FPROPER_PAIR)}isSegmentUnmapped(){return!!(this.flags&v.default.BAM_FUNMAP)}isMateUnmapped(){return!!(this.flags&v.default.BAM_FMUNMAP)}isReverseComplemented(){return!!(this.flags&v.default.BAM_FREVERSE)}isMateReverseComplemented(){return!!(this.flags&v.default.BAM_FMREVERSE)}isRead1(){return!!(this.flags&v.default.BAM_FREAD1)}isRead2(){return!!(this.flags&v.default.BAM_FREAD2)}isSecondary(){return!!(this.flags&v.default.BAM_FSECONDARY)}isFailedQc(){return!!(this.flags&v.default.BAM_FQCFAIL)}isDuplicate(){return!!(this.flags&v.default.BAM_FDUP)}isSupplementary(){return!!(this.flags&v.default.BAM_FSUPPLEMENTARY)}isDetached(){return!!(this.cramFlags&v.default.CRAM_FLAG_DETACHED)}hasMateDownStream(){return!!(this.cramFlags&v.default.CRAM_FLAG_MATE_DOWNSTREAM)}isPreservingQualityScores(){return!!(this.cramFlags&v.default.CRAM_FLAG_PRESERVE_QUAL_SCORES)}isUnknownBases(){return!!(this.cramFlags&v.default.CRAM_FLAG_NO_SEQ)}getReadBases(){if(!this.readBases&&this._refRegion){const A=function(A,t){if(!A.lengthOnRef&&!A.readLength)return null;if(A.isUnknownBases())return null;const r=A.alignmentStart-t.start;if(!A.readFeatures)return t.seq.slice(r,r+(A.lengthOnRef||0)).toUpperCase();let e="",v=r,n=0;for(;e.length<A.readLength;)if(n<A.readFeatures.length){const r=A.readFeatures[n];if("Q"===r.code||"q"===r.code)n+=1;else if(r.pos===e.length+1)if(n+=1,"b"===r.code){const A=r.data;e+=A,v+=A.length}else"B"===r.code?(e+=r.data[0],v+=1):"X"===r.code?(e+=r.sub,v+=1):"I"===r.code?e+=r.data:"D"===r.code?v+=r.data:"i"===r.code?e+=r.data:"N"===r.code?v+=r.data:"S"===r.code?e+=r.data:"P"===r.code||r.code;else if(n<A.readFeatures.length){const A=t.seq.slice(v,v+r.pos-e.length-1);e+=A,v+=A.length}}else{const r=t.seq.slice(v,v+A.readLength-e.length);e+=r,v+=r.length}return e.toUpperCase()}(this,this._refRegion);A&&(this.readBases=A)}return this.readBases}getPairOrientation(){if(!this.isSegmentUnmapped()&&this.isPaired()&&!this.isMateUnmapped()&&this.mate&&this.sequenceId===this.mate.sequenceId){const A=this.isReverseComplemented()?"R":"F",t=this.isMateReverseComplemented()?"R":"F";let r=" ",e=" ";this.isRead1()?(r="1",e="2"):this.isRead2()&&(r="2",e="1");const v=[];let n=this.templateLength||this.templateSize;if(void 0===n)throw new Error("One of templateSize and templateLength must be set");return this.alignmentStart>this.mate.alignmentStart&&n>0&&(n=-n),n>0?(v[0]=A,v[1]=r,v[2]=t,v[3]=e):(v[2]=A,v[3]=r,v[0]=t,v[1]=e),v.join("")}return null}addReferenceSequence(A,t){this.readFeatures&&this.readFeatures.forEach(r=>{"X"===r.code&&function(A,t,r,e){const v=e.refPos-t.start,j=t.seq.charAt(v);j&&(e.ref=j);let f=n[j];void 0===f&&(f=4);const s=r.substitutionMatrix[f][e.data];s&&(e.sub=s)}(0,A,t,r)}),!this.readBases&&A.start<=this.alignmentStart&&A.end>=this.alignmentStart+(this.lengthOnRef||this.readLength)-1&&(this._refRegion=A)}toJSON(){const A={};return Object.keys(this).forEach(t=>{t.startsWith("_")||(A[t]=this[t])}),A.readBases=this.getReadBases(),A}}},485:(A,t)=>{"use strict";function r(A){return("object"==typeof A&&null!==A&&"message"in A?A.message:`${A}`).replace(/\.$/,"")}Object.defineProperty(t,"__esModule",{value:!0}),t.default=class{constructor(A,t={}){this.baseOverrides={},this.url=A;const r=t.fetch||globalThis.fetch.bind(globalThis);t.overrides&&(this.baseOverrides=t.overrides),this.fetchImplementation=r}async fetch(A,t){let e;try{e=await this.fetchImplementation(A,t)}catch(v){if(!`${v}`.includes("Failed to fetch"))throw new Error(`${r(v)} fetching ${A}`,{cause:v});console.warn(`generic-filehandle: refetching ${A} to attempt to work around chrome CORS header caching bug`);try{e=await 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A)t=A,r={};else{t=A.encoding;const{encoding:e,...v}=A;r=v}const{headers:e={},signal:v,overrides:n={}}=r,j=await this.fetch(this.url,{...this.baseOverrides,...n,headers:{...this.baseOverrides.headers,...n.headers,...e},method:"GET",redirect:"follow",mode:"cors",signal:v});if(200!==j.status)throw new Error(`HTTP ${j.status} fetching ${this.url}`);if("utf8"===t)return j.text();if(t)throw new Error(`unsupported encoding: ${t}`);return j.bytes?j.bytes():new Uint8Array(await j.arrayBuffer())}async stat(){if(!this._stat&&(await this.read(10,0),!this._stat))throw new Error(`unable to determine size of file at ${this.url}`);return this._stat}async close(){}}},492:function(A,t,r){"use strict";var e=this&&this.__importDefault||function(A){return A&&A.__esModule?A:{default:A}};Object.defineProperty(t,"__esModule",{value:!0});const v=e(r(141)),n=r(761),j=r(272);class f extends v.default{constructor(A,t){if(super(A,t),"int"!==this.dataType)throw new j.CramUnimplementedError(`${this.dataType} decoding not yet implemented by SUBEXP codec`)}decode(A,t,r,e){let v,j,f=0;for(;(0,n.getBits)(t.content,e.coreBlock,1);)f+=1;return 0===f?(v=this.parameters.K,j=(0,n.getBits)(t.content,e.coreBlock,v)):(v=f+this.parameters.K-1,j=1<<v|(0,n.getBits)(t.content,e.coreBlock,v)),j-this.parameters.offset}}t.default=f},500:function(A,t,r){"use strict";var e=this&&this.__importDefault||function(A){return A&&A.__esModule?A:{default:A}};Object.defineProperty(t,"__esModule",{value:!0});const v=r(272),n=r(761),j=e(r(588)),f=e(r(685)),s=e(r(480)),b=r(580),o=r(549);function i(A,t,r,e){const n=!!(e.mate||void 0!==e.mateRecordNumber&&e.mateRecordNumber!==t);r.readName||(r.readName=String(r.uniqueId),e.readName=r.readName),r.mate={sequenceId:e.sequenceId,alignmentStart:e.alignmentStart,uniqueId:e.uniqueId},e.readName&&(r.mate.readName=e.readName),e.mate||void 0!==e.mateRecordNumber||(e.mate={sequenceId:r.sequenceId,alignmentStart:r.alignmentStart,uniqueId:r.uniqueId},r.readName&&(e.mate.readName=r.readName)),r.flags|=j.default.BAM_FPAIRED,e.flags&j.default.BAM_FUNMAP&&(r.flags|=j.default.BAM_FMUNMAP),r.flags&j.default.BAM_FUNMAP&&(e.flags|=j.default.BAM_FMUNMAP),e.flags&j.default.BAM_FREVERSE&&(r.flags|=j.default.BAM_FMREVERSE),r.flags&j.default.BAM_FREVERSE&&(e.flags|=j.default.BAM_FMREVERSE),void 0===r.templateLength&&(n?function(A,t,r){const e=function t(r){const e=[r];if(void 0!==r.mateRecordNumber&&r.mateRecordNumber>=0){const n=A[r.mateRecordNumber];if(!n)throw new v.CramMalformedError("intra-slice mate record not found, this file seems malformed");e.push(...t(n))}return e}(r),n=e.map(A=>A.alignmentStart),j=e.map(A=>A.alignmentStart+A.readLength-1),f=Math.max(...j)-Math.min(...n)+1;f>=0&&e.forEach(A=>{if(void 0!==A.templateLength)throw new v.CramMalformedError("mate pair group has some members that have template lengths already, this file seems malformed");A.templateLength=f})}(A,0,r):function(A,t){const r=Math.min(A.alignmentStart,t.alignmentStart),e=Math.max(A.alignmentStart+A.readLength-1,t.alignmentStart+t.readLength-1)-r+1;A.templateLength=e,t.templateLength=e}(r,e)),r.mateRecordNumber=void 0}class a{constructor(A,t,r){this.container=A,this.containerPosition=t,this.sliceSize=r,this.file=A.file}async getHeader(){const{majorVersion:A}=await this.file.getDefinition(),t=(0,b.getSectionParsers)(A),r=await this.container.getHeader(),e=await this.file.readBlock(r._endPosition+this.containerPosition);if("MAPPED_SLICE_HEADER"===e.contentType){const A=(0,o.parseItem)(e.content,t.cramMappedSliceHeader.parser,0,r._endPosition);return{...e,parsedContent:A}}if("UNMAPPED_SLICE_HEADER"===e.contentType){const A=(0,o.parseItem)(e.content,t.cramUnmappedSliceHeader.parser,0,r._endPosition);return{...e,parsedContent:A}}throw new v.CramMalformedError(`error reading slice header block, invalid content type ${e.contentType}`)}async getBlocks(){const A=await this.getHeader();let t=A._endPosition;const r=new Array(A.parsedContent.numBlocks);for(let A=0;A<r.length;A++){const e=await this.file.readBlock(t);r[A]=e,t=r[A]._endPosition}return r}async getCoreDataBlock(){return(await this.getBlocks())[0]}async _getBlocksContentIdIndex(){const A=await this.getBlocks(),t={};return A.forEach(A=>{"EXTERNAL_DATA"===A.contentType&&(t[A.contentId]=A)}),t}async getBlockByContentId(A){return(await this._getBlocksContentIdIndex())[A]}async getReferenceRegion(){const A=new TextDecoder("utf8"),t=(await this.getHeader()).parsedContent;if(!(0,b.isMappedSliceHeader)(t))throw new Error("slice header not mapped");if(t.refSeqId<0)return;const r=await this.container.getCompressionScheme();if(void 0===r)throw new Error("compression scheme undefined");if(t.refBaseBlockId>=0){const r=await this.getBlockByContentId(t.refBaseBlockId);if(!r)throw new v.CramMalformedError("embedded reference specified, but reference block does not exist");return{seq:A.decode(r.data),start:t.refSeqStart,end:t.refSeqStart+t.refSeqSpan-1,span:t.refSeqSpan}}if(r.referenceRequired||this.file.fetchReferenceSequenceCallback){if(!this.file.fetchReferenceSequenceCallback)throw new Error("reference sequence not embedded, and seqFetch callback not provided, cannot fetch reference sequence");const A=await this.file.fetchReferenceSequenceCallback(t.refSeqId,t.refSeqStart,t.refSeqStart+t.refSeqSpan-1);if(A.length!==t.refSeqSpan)throw new v.CramArgumentError("seqFetch callback returned a reference sequence of the wrong length");return{seq:A,start:t.refSeqStart,end:t.refSeqStart+t.refSeqSpan-1,span:t.refSeqSpan}}}getAllRecords(){return this.getRecords(()=>!0)}async _fetchRecords(){const{majorVersion:A}=await this.file.getDefinition(),t=await this.container.getCompressionScheme();if(void 0===t)throw new Error("compression scheme undefined");const r=await this.getHeader(),e=await this._getBlocksContentIdIndex();if(A>1&&this.file.options.checkSequenceMD5&&(0,b.isMappedSliceHeader)(r.parsedContent)&&r.parsedContent.refSeqId>=0&&"0000000000000000"!==r.parsedContent.md5?.join("")){const A=await this.getReferenceRegion();if(A){const{seq:t,start:e,end:n}=A,j=(0,o.sequenceMD5)(t),f=r.parsedContent.md5?.map(A=>(A<16?"0":"")+A.toString(16)).join("");if(j!==f)throw new v.CramMalformedError(`MD5 checksum reference mismatch for ref ${r.parsedContent.refSeqId} pos ${e}..${n}. recorded MD5: ${f}, calculated MD5: ${j}`)}}const j=await this.getCoreDataBlock(),a={lastAlignmentStart:(0,b.isMappedSliceHeader)(r.parsedContent)?r.parsedContent.refSeqStart:0,coreBlock:{bitPosition:7,bytePosition:0},externalBlocks:{map:new Map,getCursor(A){let t=this.map.get(A);return void 0===t&&(t={bitPosition:7,bytePosition:0},this.map.set(A,t)),t}}},g=new Map,I=A=>{let r=g.get(A);if(void 0===r){if(r=t.getCodecForDataSeries(A),!r)throw new v.CramMalformedError(`no codec defined for ${A} data series`);g.set(A,r)}return r.decode(this,j,e,a)},c=new Array(r.parsedContent.numRecords);for(let b=0;b<c.length;b+=1)try{const v=(0,f.default)(this,I,t,r,j,e,a,A,b);c[b]=new s.default({...v,uniqueId:r.contentPosition+r.parsedContent.recordCounter+b+1})}catch(A){if(A instanceof n.CramBufferOverrunError){const t=b,e=r.parsedContent.numRecords;throw new v.CramMalformedError(`Failed to decode all records in slice. Decoded ${t} of ${e} expected records. Buffer overrun suggests either: (1) file is truncated/corrupted, (2) compression scheme is incorrect, or (3) there's a bug in the decoder. Original error: ${A.message}`)}throw A}for(let A=0;A<c.length;A+=1){const t=c[A];if(t){const{mateRecordNumber:r}=t;void 0!==r&&r>=0&&c[r]&&i(c,A,t,c[r])}}return c}async getRecords(A){const t=this.container.filePosition+this.containerPosition;let r=this.file.featureCache.get(t.toString());r||(r=this._fetchRecords(),this.file.featureCache.set(t.toString(),r));const e=(await r).filter(A);if(e.length&&this.file.fetchReferenceSequenceCallback){const A=await this.getHeader();if((0,b.isMappedSliceHeader)(A.parsedContent)&&(A.parsedContent.refSeqId>=0||-2===A.parsedContent.refSeqId)){const t=A.parsedContent.refSeqId>=0?A.parsedContent.refSeqId:void 0,r=await this.container.getCompressionScheme();if(void 0===r)throw new Error("compression scheme undefined");const v={};for(const A of e){const r=void 0!==t?t:A.sequenceId;let e=v[r];e||(e={id:r,start:A.alignmentStart,end:Number.NEGATIVE_INFINITY,seq:null},v[r]=e);const 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this.getDefinition();this._sectionParsers=(0,l.getSectionParsers)(A)}let A=0,t=this._sectionParsers.cramFileDefinition.maxLength;try{for(;;){const r=await this.getContainerAtPosition(t).getHeader();if(0===A){t=r._endPosition;for(let A=0;A<r.numBlocks;A++)t=(await this.readBlock(t))._endPosition}else t+=r._size+r.length;A+=1}}catch(t){A--}return A}getContainerAtPosition(A){return new E.default(this,A)}async readBlockHeader(A){if(!this._sectionParsers){const{majorVersion:A}=await this.getDefinition();this._sectionParsers=(0,l.getSectionParsers)(A)}const{cramBlockHeader:t}=this._sectionParsers,r=await this.file.read(t.maxLength,A);return(0,I.parseItem)(r,t.parser,0,A)}async _parseSection(A,t,r=A.maxLength,e){const v=e??await this.file.read(r,t),n=(0,I.parseItem)(v,A.parser,0,t);if(n._size!==r)throw new o.CramMalformedError(`section read error: requested size ${r} does not equal parsed size ${n._size}`);return n}async _uncompressPre(A,t,r){if("gzip"===A)return await(0,c.unzip)(t);if("bzip2"===A)return await i.bz2_uncompress(t,r);if("lzma"===A)return(0,C.xzDecompress)(t);if("rans"===A)return await i.rans_uncompress(t);if("rans4x16"===A)return await i.r4x16_uncompress(t);if("arith"===A)return await i.arith_uncompress(t);if("fqzcomp"===A)return await i.fqzcomp_uncompress(t);if("tok3"===A)return await i.tok3_uncompress(t);throw new o.CramUnimplementedError(`${A} decompression not yet implemented`)}async _uncompress(A,t,r){const e=await this._uncompressPre(A,t,r);if(e.length!==r){const A=new Uint8Array(r);return A.set(e,0),A}return e}async readBlock(A){const{majorVersion:t}=await this.getDefinition();this._sectionParsers||(this._sectionParsers=(0,l.getSectionParsers)(t));const r=this._sectionParsers,e=await this.readBlockHeader(A),v=e._endPosition,n=await this.file.read(e.compressedSize,v),j="raw"!==e.compressionMethod?await this._uncompress(e.compressionMethod,n,e.uncompressedSize):n,f={...e,_endPosition:v,contentPosition:v,content:j};if(t>=3){const t=await this._parseSection(r.cramBlockCrc32,v+e.compressedSize);f.crc32=t.crc32,this.validateChecksums&&await this.checkCrc32(A,e._size+e.compressedSize,t.crc32,"block data"),f._endPosition=t._endPosition,f._size=f.compressedSize+r.cramBlockCrc32.maxLength}else f._endPosition=v+f.compressedSize,f._size=f.compressedSize;return f}}t.default=d,"getDefinition getSectionParsers getSamHeader".split(" ").forEach(A=>{(0,I.tinyMemoize)(d,A)})},761:(A,t)=>{"use strict";Object.defineProperty(t,"__esModule",{value:!0}),t.CramBufferOverrunError=void 0,t.getBits=function(A,t,e){let v=0;if(t.bytePosition+(7-t.bitPosition+e)/8>A.length)throw new r("read error during decoding. the file seems to be truncated.");for(let r=e;r;r--)v<<=1,v|=A[t.bytePosition]>>t.bitPosition&1,t.bitPosition-=1,t.bitPosition<0&&(t.bytePosition+=1),t.bitPosition&=7;return v};class r extends Error{}t.CramBufferOverrunError=r},807:function(A,t,r){"use strict";var e=this&&this.__importDefault||function(A){return A&&A.__esModule?A:{default:A}};Object.defineProperty(t,"__esModule",{value:!0});const v=e(r(141)),n=r(761),j=r(272);class f extends v.default{constructor(A,t){if(super(A,t),"int"!==this.dataType)throw new j.CramUnimplementedError(`${this.dataType} decoding not yet implemented by BETA codec`)}decode(A,t,r,e){return(0,n.getBits)(t.content,e.coreBlock,this.parameters.length)-this.parameters.offset}}t.default=f},820:(A,t)=>{"use strict";Object.defineProperty(t,"__esModule",{value:!0}),t.xzdecompressWasm=void 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"},845:function(A,t,r){"use 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file seems malformed");A.templateLength=f})}(A,0,r):function(A,t){const r=Math.min(A.alignmentStart,t.alignmentStart),e=Math.max(A.alignmentStart+A.readLength-1,t.alignmentStart+t.readLength-1)-r+1;A.templateLength=e,t.templateLength=e}(r,e)),r.mateRecordNumber=void 0}class a{constructor(A,t,r){this.container=A,this.containerPosition=t,this.sliceSize=r,this.file=A.file}async getHeader(){const{majorVersion:A}=await this.file.getDefinition(),t=(0,b.getSectionParsers)(A),r=await this.container.getHeader(),e=await this.file.readBlock(r._endPosition+this.containerPosition);if("MAPPED_SLICE_HEADER"===e.contentType){const A=(0,o.parseItem)(e.content,t.cramMappedSliceHeader.parser,0,r._endPosition);return{...e,parsedContent:A}}if("UNMAPPED_SLICE_HEADER"===e.contentType){const A=(0,o.parseItem)(e.content,t.cramUnmappedSliceHeader.parser,0,r._endPosition);return{...e,parsedContent:A}}throw new v.CramMalformedError(`error reading slice header block, invalid content type ${e.contentType}`)}async getBlocks(){const A=await this.getHeader();let t=A._endPosition;const r=new Array(A.parsedContent.numBlocks);for(let A=0;A<r.length;A++){const e=await this.file.readBlock(t);r[A]=e,t=r[A]._endPosition}return r}async getCoreDataBlock(){return(await this.getBlocks())[0]}async _getBlocksContentIdIndex(){const A=await this.getBlocks(),t={};return A.forEach(A=>{"EXTERNAL_DATA"===A.contentType&&(t[A.contentId]=A)}),t}async getBlockByContentId(A){return(await this._getBlocksContentIdIndex())[A]}async getReferenceRegion(){const A=new TextDecoder("utf8"),t=(await this.getHeader()).parsedContent;if(!(0,b.isMappedSliceHeader)(t))throw new Error("slice header not mapped");if(t.refSeqId<0)return;const r=await this.container.getCompressionScheme();if(void 0===r)throw new Error("compression scheme undefined");if(t.refBaseBlockId>=0){const r=await this.getBlockByContentId(t.refBaseBlockId);if(!r)throw new v.CramMalformedError("embedded reference specified, but reference block does not exist");return{seq:A.decode(r.data),start:t.refSeqStart,end:t.refSeqStart+t.refSeqSpan-1,span:t.refSeqSpan}}if(r.referenceRequired||this.file.fetchReferenceSequenceCallback){if(!this.file.fetchReferenceSequenceCallback)throw new Error("reference sequence not embedded, and seqFetch callback not provided, cannot fetch reference sequence");const A=await this.file.fetchReferenceSequenceCallback(t.refSeqId,t.refSeqStart,t.refSeqStart+t.refSeqSpan-1);if(A.length!==t.refSeqSpan)throw new v.CramArgumentError("seqFetch callback returned a reference sequence of the wrong length");return{seq:A,start:t.refSeqStart,end:t.refSeqStart+t.refSeqSpan-1,span:t.refSeqSpan}}}getAllRecords(){return this.getRecords(()=>!0)}async _fetchRecords(){const{majorVersion:A}=await this.file.getDefinition(),t=await this.container.getCompressionScheme();if(void 0===t)throw new Error("compression scheme undefined");const r=await this.getHeader(),e=await this._getBlocksContentIdIndex();if(A>1&&this.file.options.checkSequenceMD5&&(0,b.isMappedSliceHeader)(r.parsedContent)&&r.parsedContent.refSeqId>=0&&"0000000000000000"!==r.parsedContent.md5?.join("")){const A=await this.getReferenceRegion();if(A){const{seq:t,start:e,end:n}=A,j=(0,o.sequenceMD5)(t),f=r.parsedContent.md5?.map(A=>(A<16?"0":"")+A.toString(16)).join("");if(j!==f)throw new v.CramMalformedError(`MD5 checksum reference mismatch for ref ${r.parsedContent.refSeqId} pos ${e}..${n}. recorded MD5: ${f}, calculated MD5: ${j}`)}}const j=await this.getCoreDataBlock(),a={lastAlignmentStart:(0,b.isMappedSliceHeader)(r.parsedContent)?r.parsedContent.refSeqStart:0,coreBlock:{bitPosition:7,bytePosition:0},externalBlocks:{map:new Map,getCursor(A){let t=this.map.get(A);return void 0===t&&(t={bitPosition:7,bytePosition:0},this.map.set(A,t)),t}}},g=new Map,I=A=>{let r=g.get(A);if(void 0===r){if(r=t.getCodecForDataSeries(A),!r)throw new v.CramMalformedError(`no codec defined for ${A} data series`);g.set(A,r)}return r.decode(this,j,e,a)},c=new Array(r.parsedContent.numRecords);for(let b=0;b<c.length;b+=1)try{const v=(0,f.default)(this,I,t,r,j,e,a,A,b);c[b]=new s.default({...v,uniqueId:r.contentPosition+r.parsedContent.recordCounter+b+1})}catch(A){if(A instanceof n.CramBufferOverrunError){const t=b,e=r.parsedContent.numRecords;throw new v.CramMalformedError(`Failed to decode all records in slice. Decoded ${t} of ${e} expected records. Buffer overrun suggests either: (1) file is truncated/corrupted, (2) compression scheme is incorrect, or (3) there's a bug in the decoder. Original error: ${A.message}`)}throw A}for(let A=0;A<c.length;A+=1){const t=c[A];if(t){const{mateRecordNumber:r}=t;void 0!==r&&r>=0&&c[r]&&i(c,A,t,c[r])}}return c}async getRecords(A){const t=this.container.filePosition+this.containerPosition;let r=this.file.featureCache.get(t.toString());r||(r=this._fetchRecords(),this.file.featureCache.set(t.toString(),r));const e=(await r).filter(A);if(e.length&&this.file.fetchReferenceSequenceCallback){const A=await this.getHeader();if((0,b.isMappedSliceHeader)(A.parsedContent)&&(A.parsedContent.refSeqId>=0||-2===A.parsedContent.refSeqId)){const t=A.parsedContent.refSeqId>=0?A.parsedContent.refSeqId:void 0,r=await this.container.getCompressionScheme();if(void 0===r)throw new Error("compression scheme undefined");const v={};for(const A of e){const r=void 0!==t?t:A.sequenceId;let e=v[r];e||(e={id:r,start:A.alignmentStart,end:Number.NEGATIVE_INFINITY,seq:null},v[r]=e);const 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r=e.bytesToWords(A),s=8*A.length,b=1732584193,o=-271733879,i=-1732584194,a=271733878,g=0;g<r.length;g++)r[g]=16711935&(r[g]<<8|r[g]>>>24)|4278255360&(r[g]<<24|r[g]>>>8);r[s>>>5]|=128<<s%32,r[14+(s+64>>>9<<4)]=s;var I=f._ff,c=f._gg,E=f._hh,l=f._ii;for(g=0;g<r.length;g+=16){var C=b,d=o,u=i,B=a;b=I(b,o,i,a,r[g+0],7,-680876936),a=I(a,b,o,i,r[g+1],12,-389564586),i=I(i,a,b,o,r[g+2],17,606105819),o=I(o,i,a,b,r[g+3],22,-1044525330),b=I(b,o,i,a,r[g+4],7,-176418897),a=I(a,b,o,i,r[g+5],12,1200080426),i=I(i,a,b,o,r[g+6],17,-1473231341),o=I(o,i,a,b,r[g+7],22,-45705983),b=I(b,o,i,a,r[g+8],7,1770035416),a=I(a,b,o,i,r[g+9],12,-1958414417),i=I(i,a,b,o,r[g+10],17,-42063),o=I(o,i,a,b,r[g+11],22,-1990404162),b=I(b,o,i,a,r[g+12],7,1804603682),a=I(a,b,o,i,r[g+13],12,-40341101),i=I(i,a,b,o,r[g+14],17,-1502002290),b=c(b,o=I(o,i,a,b,r[g+15],22,1236535329),i,a,r[g+1],5,-165796510),a=c(a,b,o,i,r[g+6],9,-1069501632),i=c(i,a,b,o,r[g+11],14,643717713),o=c(o,i,a,b,r[g+0],20,-373897302),b=c(b,o,i,a,r[g+5],5,-701558691),a=c(a,b,o,i,r[g+10],9,38016083),i=c(i,a,b,o,r[g+15],14,-660478335),o=c(o,i,a,b,r[g+4],20,-405537848),b=c(b,o,i,a,r[g+9],5,568446438),a=c(a,b,o,i,r[g+14],9,-1019803690),i=c(i,a,b,o,r[g+3],14,-187363961),o=c(o,i,a,b,r[g+8],20,1163531501),b=c(b,o,i,a,r[g+13],5,-1444681467),a=c(a,b,o,i,r[g+2],9,-51403784),i=c(i,a,b,o,r[g+7],14,1735328473),b=E(b,o=c(o,i,a,b,r[g+12],20,-1926607734),i,a,r[g+5],4,-378558),a=E(a,b,o,i,r[g+8],11,-2022574463),i=E(i,a,b,o,r[g+11],16,1839030562),o=E(o,i,a,b,r[g+14],23,-35309556),b=E(b,o,i,a,r[g+1],4,-1530992060),a=E(a,b,o,i,r[g+4],11,1272893353),i=E(i,a,b,o,r[g+7],16,-155497632),o=E(o,i,a,b,r[g+10],23,-1094730640),b=E(b,o,i,a,r[g+13],4,681279174),a=E(a,b,o,i,r[g+0],11,-358537222),i=E(i,a,b,o,r[g+3],16,-722521979),o=E(o,i,a,b,r[g+6],23,76029189),b=E(b,o,i,a,r[g+9],4,-640364487),a=E(a,b,o,i,r[g+12],11,-421815835),i=E(i,a,b,o,r[g+15],16,530742520),b=l(b,o=E(o,i,a,b,r[g+2],23,-995338651),i,a,r[g+0],6,-198630844),a=l(a,b,o,i,r[g+7],10,1126891415),i=l(i,a,b,o,r[g+14],15,-1416354905),o=l(o,i,a,b,r[g+5],21,-57434055),b=l(b,o,i,a,r[g+12],6,1700485571),a=l(a,b,o,i,r[g+3],10,-1894986606),i=l(i,a,b,o,r[g+10],15,-1051523),o=l(o,i,a,b,r[g+1],21,-2054922799),b=l(b,o,i,a,r[g+8],6,1873313359),a=l(a,b,o,i,r[g+15],10,-30611744),i=l(i,a,b,o,r[g+6],15,-1560198380),o=l(o,i,a,b,r[g+13],21,1309151649),b=l(b,o,i,a,r[g+4],6,-145523070),a=l(a,b,o,i,r[g+11],10,-1120210379),i=l(i,a,b,o,r[g+2],15,718787259),o=l(o,i,a,b,r[g+9],21,-343485551),b=b+C>>>0,o=o+d>>>0,i=i+u>>>0,a=a+B>>>0}return e.endian([b,o,i,a])})._ff=function(A,t,r,e,v,n,j){var f=A+(t&r|~t&e)+(v>>>0)+j;return(f<<n|f>>>32-n)+t},f._gg=function(A,t,r,e,v,n,j){var f=A+(t&e|r&~e)+(v>>>0)+j;return(f<<n|f>>>32-n)+t},f._hh=function(A,t,r,e,v,n,j){var f=A+(t^r^e)+(v>>>0)+j;return(f<<n|f>>>32-n)+t},f._ii=function(A,t,r,e,v,n,j){var f=A+(r^(t|~e))+(v>>>0)+j;return(f<<n|f>>>32-n)+t},f._blocksize=16,f._digestsize=16,A.exports=function(A,t){if(null==A)throw new Error("Illegal argument "+A);var r=e.wordsToBytes(f(A,t));return t&&t.asBytes?r:t&&t.asString?j.bytesToString(r):e.bytesToHex(r)}},549:function(A,t,r){"use strict";var e=this&&this.__importDefault||function(A){return A&&A.__esModule?A:{default:A}};Object.defineProperty(t,"__esModule",{value:!0}),t.TWO_PWR_56_DBL=t.TWO_PWR_24_DBL=t.TWO_PWR_64_DBL=t.TWO_PWR_32_DBL=t.TWO_PWR_16_DBL=void 0,t.itf8Size=function(A){return-128&A?-16384&A?-2097152&A?-268435456&A?5:4:3:2:1},t.parseItf8=function(A,t){let r=t;const e=A[r];let v;return e<128?(v=e,r+=1):e<192?(v=(63&e)<<8|A[r+1],r+=2):e<224?(v=(31&e)<<16|A[r+1]<<8|A[r+2],r+=3):e<240?(v=(15&e)<<24|A[r+1]<<16|A[r+2]<<8|A[r+3],r+=4):(v=(15&e)<<28|A[r+1]<<20|A[r+2]<<12|A[r+3]<<4|15&A[r+4],r+=5),[v,r-t]},t.parseLtf8=function(A,r){let e=r;const v=A[e];let n;return v<128?(n=v,e+=1):v<192?(n=16383&(v<<8|A[e+1]),e+=2):v<224?(n=(63&v)<<16|A[e+1]<<8|A[e+2],e+=3):v<240?(n=(31&v)<<24|A[e+1]<<16|A[e+2]<<8|A[e+3],e+=4):v<248?(n=(15&A[e])*t.TWO_PWR_32_DBL+(A[e+1]<<24|A[e+2]<<16|A[e+3]<<8|A[e+4]),e+=5):v<252?(n=((7&A[e])<<8|A[e+1])*t.TWO_PWR_32_DBL+(A[e+2]<<24|A[e+3]<<16|A[e+4]<<8|A[e+5]),e+=6):v<254?(n=((3&A[e])<<16|A[e+1]<<8|A[e+2])*t.TWO_PWR_32_DBL+(A[e+3]<<24|A[e+4]<<16|A[e+5]<<8|A[e+6]),e+=7):v<255?(n=(A[e+1]<<24|A[e+2]<<16|A[e+3]<<8|A[e+4])*t.TWO_PWR_32_DBL+(A[e+5]<<24|A[e+6]<<16|A[e+7]<<8|A[e+8]),e+=8):(n=A[e+1]*t.TWO_PWR_56_DBL+(A[e+2]<<24|A[e+3]<<16|A[e+4]<<8|A[e+5])*t.TWO_PWR_32_DBL+(A[e+6]<<24|A[e+7]<<16|A[e+8]<<8|A[e+9]),e+=9),[n,e-r]},t.parseItem=function(A,t,r=0,e=0){const{offset:v,value:n}=t(A,r);return{...n,_endPosition:v+e,_size:v-r}},t.tinyMemoize=function(A,t){const r=A.prototype[t],e=`_memo_${t}`;A.prototype[t]=function(){let A=this[e];return void 0===A&&(A=r.call(this),this[e]=A,Promise.resolve(A).catch(()=>{delete this[e]})),A}},t.sequenceMD5=function(A){return(0,v.default)(A.toUpperCase().replaceAll(/[^\u0021-\u007e]/g,""))};const v=e(r(503));t.TWO_PWR_16_DBL=65536,t.TWO_PWR_32_DBL=t.TWO_PWR_16_DBL*t.TWO_PWR_16_DBL,t.TWO_PWR_64_DBL=t.TWO_PWR_32_DBL*t.TWO_PWR_32_DBL,t.TWO_PWR_24_DBL=1<<24,t.TWO_PWR_56_DBL=t.TWO_PWR_24_DBL*t.TWO_PWR_32_DBL},562:(A,t,r)=>{"use strict";Object.defineProperty(t,"__esModule",{value:!0}),t.bz2_uncompress=t.tok3_uncompress=t.fqzcomp_uncompress=t.arith_uncompress=t.r4x16_uncompress=t.r4x8_uncompress=t.rans_uncompress=void 0;var e=r(282);Object.defineProperty(t,"rans_uncompress",{enumerable:!0,get:function(){return e.rans_uncompress}}),Object.defineProperty(t,"r4x8_uncompress",{enumerable:!0,get:function(){return e.rans_uncompress}}),Object.defineProperty(t,"r4x16_uncompress",{enumerable:!0,get:function(){return e.r4x16_uncompress}}),Object.defineProperty(t,"arith_uncompress",{enumerable:!0,get:function(){return e.arith_uncompress}}),Object.defineProperty(t,"fqzcomp_uncompress",{enumerable:!0,get:function(){return e.fqzcomp_uncompress}}),Object.defineProperty(t,"tok3_uncompress",{enumerable:!0,get:function(){return e.tok3_uncompress}}),Object.defineProperty(t,"bz2_uncompress",{enumerable:!0,get:function(){return e.bz2_uncompress}})},580:(A,t,r)=>{"use strict";Object.defineProperty(t,"__esModule",{value:!0}),t.cramFileDefinition=v,t.cramBlockHeader=n,t.cramBlockCrc32=j,t.cramTagDictionary=s,t.cramPreservationMap=b,t.isMappedSliceHeader=function(A){return"number"==typeof A.refSeqId},t.getSectionParsers=function(A){return{cramFileDefinition:v(),cramBlockHeader:n(),cramBlockCrc32:j(),cramDataSeriesEncodingMap:I(),cramTagEncodingMap:c(),cramCompressionHeader:{parser:(A,t)=>{const{value:r,offset:e}=b().parser(A,t);t=e;const{value:v,offset:n}=I().parser(A,t);t=n;const{value:j,offset:f}=c().parser(A,t);return t=f,{value:{dataSeriesEncoding:o(v),preservation:o(r),tagEncoding:o(j)},offset:t}}},cramEncoding:{parser:(A,t)=>g(A,t)},cramUnmappedSliceHeader:i(A),cramMappedSliceHeader:a(A),cramContainerHeader1:E(A),cramContainerHeader2:l(A)}};const e=r(549);function v(){return{parser:(A,t=0)=>{const r=new DataView(A.buffer,A.byteOffset,A.length),e=new TextDecoder("utf8");let v=0;const n=e.decode(A.subarray(v,v+4));v+=4;const j=r.getUint8(v);v+=1;const f=r.getUint8(v);v+=1;const s=e.decode(A.subarray(v,v+20)).replaceAll("\0","");return v+=20,{value:{magic:n,majorVersion:j,minorVersion:f,fileId:s},offset:v}},maxLength:26}}function n(){return{parser:(A,t=0)=>{const r=A,v=new DataView(r.buffer,r.byteOffset,r.length);let n=0;const j=v.getUint8(n),f=["raw","gzip","bzip2","lzma","rans","rans4x16","arith","fqzcomp","tok3"][j];if(!f)throw new Error(`compression method number ${j} not implemented`);n+=1;const 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b(){return{parser:(A,t)=>{const r=A,v=new DataView(r.buffer,r.byteOffset,r.length),[n,j]=(0,e.parseItf8)(A,t);t+=j;const[f,b]=(0,e.parseItf8)(A,t);t+=b;const o=[];for(let r=0;r<f;r++){const r=String.fromCharCode(A[t])+String.fromCharCode(A[t+1]);if(t+=2,"MI"===r||"UI"===r||"PI"===r||"RN"===r||"AP"===r||"RR"===r)o.push({key:r,value:!!v.getUint8(t)}),t+=1;else if("SM"===r)o.push({key:r,value:[v.getUint8(t),v.getUint8(t+1),v.getUint8(t+2),v.getUint8(t+3),v.getUint8(t+4)]}),t+=5;else{if("TD"!==r)throw new Error(`unknown key ${r}`);{const{offset:e,value:v}=s().parser(A,t);o.push({key:r,value:v.ents}),t=e}}}return{value:{mapSize:n,mapCount:f,ents:o},offset:t}}}}function o(A){const t={};for(const{key:r,value:e}of A.ents)t[r]&&console.warn(`duplicate key ${r} in map`),t[r]=e;return t}function i(A){let t=0;return t+=5,t+=9,t+=10,t+=16,{parser:(t,r)=>{const[v,n]=(0,e.parseItf8)(t,r);r+=n;let j=0;if(A>=3){const[A,v]=(0,e.parseLtf8)(t,r);r+=v,j=A}else 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u;return r+=d,A>=2&&(u=[...t.subarray(r,r+16)],r+=16),{value:{md5:u,numBlocks:g,numRecords:o,numContentIds:c,refSeqSpan:s,refSeqId:v,refSeqStart:j,recordCounter:a,refBaseBlockId:C,contentIds:l},offset:r}},maxLength:A=>60+5*A}}function g(A,t){const r=A,v=new DataView(r.buffer,r.byteOffset,r.length),[n,j]=(0,e.parseItf8)(A,t);t+=j;const[f,s]=(0,e.parseItf8)(A,t);t+=s;const b={};if(0===n);else if(1===n){const[r,v]=(0,e.parseItf8)(A,t);b.blockContentId=r,t+=v}else if(2===n){const[r,v]=(0,e.parseItf8)(A,t);b.offset=r,t+=v;const[n,j]=(0,e.parseItf8)(A,t);b.M=n,t+=j}else if(3===n){const r=(0,e.parseItf8)(A,t),v=r[0];t+=r[1];const n=[];for(let r=0;r<v;r++){const r=(0,e.parseItf8)(A,t);n.push(r[0]),t+=r[1]}b.symbols=n;const j=(0,e.parseItf8)(A,t),f=r[0];b.numLengths=f,b.numCodes=v,b.numLengths=f,t+=j[1];const s=[];for(let r=0;r<f;r++){const r=(0,e.parseItf8)(A,t);t+=r[1],s.push(r[0])}b.bitLengths=s}else 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A.getFirstBlock()).content,r=new DataView(t.buffer).getInt32(0,!0),e=new TextDecoder("utf8").decode(t.subarray(4,4+r));return this.header=e,(0,g.parseHeaderText)(e)}async getHeaderText(){return await this.getSamHeader(),this.header}async getContainerById(A){if(!this._sectionParsers){const{majorVersion:A}=await this.getDefinition();this._sectionParsers=(0,l.getSectionParsers)(A)}let t,r=this._sectionParsers.cramFileDefinition.maxLength;for(let e=0;e<=A;e++){t=this.getContainerAtPosition(r);const A=await t.getHeader();if(0===e){r=A._endPosition;for(let t=0;t<A.numBlocks;t++)r=(await this.readBlock(r))._endPosition}else r+=A._size+A.length}return t}async checkCrc32(A,t,r,e){const v=await this.file.read(t,A),n=(0,s.default)(v)>>>0;if(n!==r)throw new o.CramMalformedError(`crc mismatch in ${e}: recorded CRC32 = ${r}, but calculated CRC32 = ${n}`)}async containerCount(){if(!this._sectionParsers){const{majorVersion:A}=await this.getDefinition();this._sectionParsers=(0,l.getSectionParsers)(A)}let A=0,t=this._sectionParsers.cramFileDefinition.maxLength;try{for(;;){const r=await this.getContainerAtPosition(t).getHeader();if(0===A){t=r._endPosition;for(let A=0;A<r.numBlocks;A++)t=(await this.readBlock(t))._endPosition}else t+=r._size+r.length;A+=1}}catch(t){A--}return A}getContainerAtPosition(A){return new E.default(this,A)}async readBlockHeader(A){if(!this._sectionParsers){const{majorVersion:A}=await this.getDefinition();this._sectionParsers=(0,l.getSectionParsers)(A)}const{cramBlockHeader:t}=this._sectionParsers,r=await this.file.read(t.maxLength,A);return(0,I.parseItem)(r,t.parser,0,A)}async _parseSection(A,t,r=A.maxLength,e){const v=e??await this.file.read(r,t),n=(0,I.parseItem)(v,A.parser,0,t);if(n._size!==r)throw new o.CramMalformedError(`section read error: requested size ${r} does not equal parsed size ${n._size}`);return n}async _uncompressPre(A,t,r){if("gzip"===A)return await(0,c.unzip)(t);if("bzip2"===A)return await i.bz2_uncompress(t,r);if("lzma"===A)return(0,C.xzDecompress)(t);if("rans"===A)return await i.rans_uncompress(t);if("rans4x16"===A)return await i.r4x16_uncompress(t);if("arith"===A)return await i.arith_uncompress(t);if("fqzcomp"===A)return await i.fqzcomp_uncompress(t);if("tok3"===A)return await i.tok3_uncompress(t);throw new o.CramUnimplementedError(`${A} decompression not yet implemented`)}async _uncompress(A,t,r){const e=await this._uncompressPre(A,t,r);if(e.length!==r){const A=new Uint8Array(r);return A.set(e,0),A}return e}async readBlock(A){const{majorVersion:t}=await this.getDefinition();this._sectionParsers||(this._sectionParsers=(0,l.getSectionParsers)(t));const r=this._sectionParsers,e=await this.readBlockHeader(A),v=e._endPosition,n=await this.file.read(e.compressedSize,v),j="raw"!==e.compressionMethod?await this._uncompress(e.compressionMethod,n,e.uncompressedSize):n,f={...e,_endPosition:v,contentPosition:v,content:j};if(t>=3){const t=await this._parseSection(r.cramBlockCrc32,v+e.compressedSize);f.crc32=t.crc32,this.validateChecksums&&await this.checkCrc32(A,e._size+e.compressedSize,t.crc32,"block data"),f._endPosition=t._endPosition,f._size=f.compressedSize+r.cramBlockCrc32.maxLength}else f._endPosition=v+f.compressedSize,f._size=f.compressedSize;return f}}t.default=d,"getDefinition getSectionParsers getSamHeader".split(" ").forEach(A=>{(0,I.tinyMemoize)(d,A)})},761:(A,t)=>{"use strict";Object.defineProperty(t,"__esModule",{value:!0}),t.CramBufferOverrunError=void 0,t.getBits=function(A,t,e){let v=0;if(t.bytePosition+(7-t.bitPosition+e)/8>A.length)throw new r("read error during decoding. the file seems to be truncated.");for(let r=e;r;r--)v<<=1,v|=A[t.bytePosition]>>t.bitPosition&1,t.bitPosition-=1,t.bitPosition<0&&(t.bytePosition+=1),t.bitPosition&=7;return v};class r extends Error{}t.CramBufferOverrunError=r},807:function(A,t,r){"use strict";var e=this&&this.__importDefault||function(A){return A&&A.__esModule?A:{default:A}};Object.defineProperty(t,"__esModule",{value:!0});const v=e(r(141)),n=r(761),j=r(272);class f extends v.default{constructor(A,t){if(super(A,t),"int"!==this.dataType)throw new j.CramUnimplementedError(`${this.dataType} decoding not yet implemented by BETA codec`)}decode(A,t,r,e){return(0,n.getBits)(t.content,e.coreBlock,this.parameters.length)-this.parameters.offset}}t.default=f},820:(A,t)=>{"use strict";Object.defineProperty(t,"__esModule",{value:!0}),t.xzdecompressWasm=void 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