@gmod/cram 5.1.0 → 6.0.0

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (80) hide show
  1. package/dist/cram-bundle.js +1 -1
  2. package/dist/cram-bundle.js.LICENSE.txt +0 -6
  3. package/dist/cramFile/codecs/byteArrayLength.js +8 -4
  4. package/dist/cramFile/codecs/byteArrayLength.js.map +1 -1
  5. package/dist/cramFile/codecs/external.d.ts +1 -4
  6. package/dist/cramFile/codecs/external.js +15 -20
  7. package/dist/cramFile/codecs/external.js.map +1 -1
  8. package/dist/cramFile/file.d.ts +2 -7
  9. package/dist/cramFile/file.js +22 -22
  10. package/dist/cramFile/file.js.map +1 -1
  11. package/dist/cramFile/slice/index.js +14 -5
  12. package/dist/cramFile/slice/index.js.map +1 -1
  13. package/dist/cramFile/util.js +4 -3
  14. package/dist/cramFile/util.js.map +1 -1
  15. package/dist/indexedCramFile.js +15 -4
  16. package/dist/indexedCramFile.js.map +1 -1
  17. package/dist/rans/d04.js +42 -16
  18. package/dist/rans/d04.js.map +1 -1
  19. package/dist/rans/d14.js +60 -23
  20. package/dist/rans/d14.js.map +1 -1
  21. package/dist/rans/decoding.js +3 -4
  22. package/dist/rans/decoding.js.map +1 -1
  23. package/dist/rans/frequencies.js +18 -24
  24. package/dist/rans/frequencies.js.map +1 -1
  25. package/dist/rans/index.js +9 -14
  26. package/dist/rans/index.js.map +1 -1
  27. package/dist/unzip.d.ts +1 -1
  28. package/dist/xz-decompress/wasm.d.ts +1 -0
  29. package/dist/xz-decompress/wasm.js +5 -0
  30. package/dist/xz-decompress/wasm.js.map +1 -0
  31. package/dist/xz-decompress/xz-decompress.d.ts +1 -0
  32. package/dist/xz-decompress/xz-decompress.js +123 -0
  33. package/dist/xz-decompress/xz-decompress.js.map +1 -0
  34. package/esm/cramFile/codecs/byteArrayLength.js +8 -4
  35. package/esm/cramFile/codecs/byteArrayLength.js.map +1 -1
  36. package/esm/cramFile/codecs/external.d.ts +1 -4
  37. package/esm/cramFile/codecs/external.js +15 -20
  38. package/esm/cramFile/codecs/external.js.map +1 -1
  39. package/esm/cramFile/file.d.ts +2 -7
  40. package/esm/cramFile/file.js +22 -22
  41. package/esm/cramFile/file.js.map +1 -1
  42. package/esm/cramFile/slice/index.js +14 -5
  43. package/esm/cramFile/slice/index.js.map +1 -1
  44. package/esm/cramFile/util.js +4 -3
  45. package/esm/cramFile/util.js.map +1 -1
  46. package/esm/indexedCramFile.js +15 -4
  47. package/esm/indexedCramFile.js.map +1 -1
  48. package/esm/rans/d04.js +42 -16
  49. package/esm/rans/d04.js.map +1 -1
  50. package/esm/rans/d14.js +60 -20
  51. package/esm/rans/d14.js.map +1 -1
  52. package/esm/rans/decoding.js +3 -4
  53. package/esm/rans/decoding.js.map +1 -1
  54. package/esm/rans/frequencies.js +18 -24
  55. package/esm/rans/frequencies.js.map +1 -1
  56. package/esm/rans/index.js +9 -14
  57. package/esm/rans/index.js.map +1 -1
  58. package/esm/unzip.d.ts +1 -1
  59. package/esm/xz-decompress/wasm.d.ts +1 -0
  60. package/esm/xz-decompress/wasm.js +2 -0
  61. package/esm/xz-decompress/wasm.js.map +1 -0
  62. package/esm/xz-decompress/xz-decompress.d.ts +1 -0
  63. package/esm/xz-decompress/xz-decompress.js +120 -0
  64. package/esm/xz-decompress/xz-decompress.js.map +1 -0
  65. package/package.json +3 -4
  66. package/src/cramFile/codecs/byteArrayLength.ts +8 -4
  67. package/src/cramFile/codecs/external.ts +19 -31
  68. package/src/cramFile/container/compressionScheme.ts +1 -1
  69. package/src/cramFile/file.ts +27 -27
  70. package/src/cramFile/slice/index.ts +18 -8
  71. package/src/cramFile/util.ts +4 -3
  72. package/src/indexedCramFile.ts +20 -7
  73. package/src/rans/d04.ts +48 -19
  74. package/src/rans/d14.ts +69 -23
  75. package/src/rans/decoding.ts +3 -4
  76. package/src/rans/frequencies.ts +18 -24
  77. package/src/rans/index.ts +10 -14
  78. package/src/unzip.ts +1 -1
  79. package/src/xz-decompress/wasm.ts +2 -0
  80. package/src/xz-decompress/xz-decompress.ts +155 -0
package/dist/cram-bundle.js CHANGED
@@ -1,2 +1,2 @@
1
1
  /*! For license information please see cram-bundle.js.LICENSE.txt */
2
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t=e%8,r=(e-t)/8;this.bitOffset=t,this.stream.seek(r),this.hasByte=!1}pi(){const e=new Uint8Array(6);for(let t=0;t<e.length;t++)e[t]=this.read(8);return(0,n.toHex)(e)}}},86:(e,t,r)=>{const n=r(1308).A;e.exports=n,e.exports.default=n},357:(e,t)=>{"use strict";Object.defineProperty(t,"__esModule",{value:!0}),t.default=function(e,t,n,a){var i=r(),s=a+n;e^=-1;for(var A=a;A<s;A++)e=e>>>8^i[255&(e^t[A])];return-1^e};let r=function(){const e=function(){for(var e,t=[],r=0;r<256;r++){e=r;for(var n=0;n<8;n++)e=1&e?3988292384^e>>>1:e>>>1;t[r]=e}return t}();return r=()=>e,e}},437:function(e,t,r){"use strict";var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.ungzip=t.Inflate=void 0,t.inflate=u,t.inflateRaw=function(e,t){return(t=t||{}).raw=!0,u(e,t)};const a=r(5739),i=r(4082),s=r(27),A=n(r(2664)),o=r(7281),c=n(r(9368)),d=n(r(6288));var l=Object.prototype.toString;class f{constructor(e){if(!(this instanceof f))return new f(e);this.options=(0,a.assign)({chunkSize:16384,windowBits:0,to:""},e||{});var t=this.options;t.raw&&t.windowBits>=0&&t.windowBits<16&&(t.windowBits=-t.windowBits,0===t.windowBits&&(t.windowBits=-15)),!(t.windowBits>=0&&t.windowBits<16)||e&&e.windowBits||(t.windowBits+=32),t.windowBits>15&&t.windowBits<48&&(15&t.windowBits||(t.windowBits|=15)),this.err=0,this.msg="",this.ended=!1,this.chunks=[],this.strm=new d.default,this.strm.avail_out=0;var r=(0,o.inflateInit2)(this.strm,t.windowBits);if(r!==s.Z_OK)throw new Error(c.default[r]);if(this.header=new A.default,(0,o.inflateGetHeader)(this.strm,this.header),t.dictionary&&("string"==typeof t.dictionary?t.dictionary=(0,i.string2buf)(t.dictionary):"[object ArrayBuffer]"===l.call(t.dictionary)&&(t.dictionary=new Uint8Array(t.dictionary)),t.raw&&(r=(0,o.inflateSetDictionary)(this.strm,t.dictionary))!==s.Z_OK))throw new Error(c.default[r])}push(e,t){var r,n,A,c,d,f,u=this.strm,h=this.options.chunkSize,g=this.options.dictionary,C=!1;if(this.ended)return!1;n=t===~~t?t:!0===t?s.Z_FINISH:s.Z_NO_FLUSH,"string"==typeof e?u.input=(0,i.binstring2buf)(e):"[object ArrayBuffer]"===l.call(e)?u.input=new Uint8Array(e):u.input=e,u.next_in=0,u.avail_in=u.input.length;do{if(0===u.avail_out&&(u.output=(0,a.Buf8)(h),u.next_out=0,u.avail_out=h),(r=(0,o.inflate)(u,s.Z_NO_FLUSH))===s.Z_NEED_DICT&&g&&(f="string"==typeof g?(0,i.string2buf)(g):"[object ArrayBuffer]"===l.call(g)?new Uint8Array(g):g,r=(0,o.inflateSetDictionary)(this.strm,f)),r===s.Z_BUF_ERROR&&!0===C&&(r=s.Z_OK,C=!1),r!==s.Z_STREAM_END&&r!==s.Z_OK)return this.onEnd(r),this.ended=!0,!1;u.next_out&&(0!==u.avail_out&&r!==s.Z_STREAM_END&&(0!==u.avail_in||n!==s.Z_FINISH&&n!==s.Z_SYNC_FLUSH)||("string"===this.options.to?(A=(0,i.utf8border)(u.output,u.next_out),c=u.next_out-A,d=(0,i.buf2string)(u.output,A),u.next_out=c,u.avail_out=h-c,c&&(0,a.arraySet)(u.output,u.output,A,c,0),this.onData(d)):this.onData((0,a.shrinkBuf)(u.output,u.next_out)))),0===u.avail_in&&0===u.avail_out&&(C=!0)}while((u.avail_in>0||0===u.avail_out)&&r!==s.Z_STREAM_END);return r===s.Z_STREAM_END&&(n=s.Z_FINISH),n===s.Z_FINISH?(r=(0,o.inflateEnd)(this.strm),this.onEnd(r),this.ended=!0,r===s.Z_OK):n!==s.Z_SYNC_FLUSH||(this.onEnd(s.Z_OK),u.avail_out=0,!0)}onData(e){this.chunks.push(e)}onEnd(e){e===s.Z_OK&&("string"===this.options.to?this.result=this.chunks.join(""):this.result=(0,a.flattenChunks)(this.chunks)),this.chunks=[],this.err=e,this.msg=this.strm.msg}}function u(e,t){var r=new f(t);if(r.push(e,!0),r.err)throw r.msg||c.default[r.err];return r.result}t.Inflate=f,t.ungzip=u},453:function(e,t,r){"use strict";var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.Deflate=void 0,t.deflate=f,t.deflateRaw=function(e,t){return(t=t||{}).raw=!0,f(e,t)},t.gzip=function(e,t){return(t=t||{}).gzip=!0,f(e,t)};const a=r(5739),i=r(4082),s=r(27),A=r(4297),o=n(r(9368)),c=n(r(6288));var d=Object.prototype.toString;class l{constructor(e){this.options=(0,a.assign)({level:s.Z_DEFAULT_COMPRESSION,method:s.Z_DEFLATED,chunkSize:16384,windowBits:15,memLevel:8,strategy:s.Z_DEFAULT_STRATEGY,to:""},e||{});var t=this.options;t.raw&&t.windowBits>0?t.windowBits=-t.windowBits:t.gzip&&t.windowBits>0&&t.windowBits<16&&(t.windowBits+=16),this.err=0,this.msg="",this.ended=!1,this.chunks=[],this.strm=new c.default,this.strm.avail_out=0;var r=(0,A.deflateInit2)(this.strm,t.level,t.method,t.windowBits,t.memLevel,t.strategy);if(r!==s.Z_OK)throw new Error(o.default[r]);if(t.header&&(0,A.deflateSetHeader)(this.strm,t.header),t.dictionary){var n;if(n="string"==typeof t.dictionary?(0,i.string2buf)(t.dictionary):"[object ArrayBuffer]"===d.call(t.dictionary)?new Uint8Array(t.dictionary):t.dictionary,(r=(0,A.deflateSetDictionary)(this.strm,n))!==s.Z_OK)throw new Error(o.default[r]);this._dict_set=!0}}push(e,t){var r,n,o=this.strm,c=this.options.chunkSize;if(this.ended)return!1;n=t===~~t?t:!0===t?s.Z_FINISH:s.Z_NO_FLUSH,"string"==typeof e?o.input=(0,i.string2buf)(e):"[object ArrayBuffer]"===d.call(e)?o.input=new Uint8Array(e):o.input=e,o.next_in=0,o.avail_in=o.input.length;do{if(0===o.avail_out&&(o.output=(0,a.Buf8)(c),o.next_out=0,o.avail_out=c),(r=(0,A.deflate)(o,n))!==s.Z_STREAM_END&&r!==s.Z_OK)return this.onEnd(r),this.ended=!0,!1;0!==o.avail_out&&(0!==o.avail_in||n!==s.Z_FINISH&&n!==s.Z_SYNC_FLUSH)||("string"===this.options.to?this.onData((0,i.buf2binstring)((0,a.shrinkBuf)(o.output,o.next_out))):this.onData((0,a.shrinkBuf)(o.output,o.next_out)))}while((o.avail_in>0||0===o.avail_out)&&r!==s.Z_STREAM_END);return n===s.Z_FINISH?(r=(0,A.deflateEnd)(this.strm),this.onEnd(r),this.ended=!0,r===s.Z_OK):n!==s.Z_SYNC_FLUSH||(this.onEnd(s.Z_OK),o.avail_out=0,!0)}onData(e){this.chunks.push(e)}onEnd(e){e===s.Z_OK&&("string"===this.options.to?this.result=this.chunks.join(""):this.result=(0,a.flattenChunks)(this.chunks)),this.chunks=[],this.err=e,this.msg=this.strm.msg}}function f(e,t){var r=new l(t);if(r.push(e,!0),r.err)throw r.msg||o.default[r.err];return r.result}t.Deflate=l},500:function(e,t,r){"use strict";var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const a=r(6272),i=r(6761),s=n(r(588)),A=n(r(9685)),o=n(r(7480)),c=r(7580),d=r(2549);function l(e,t,r,n){const i=!!(n.mate||void 0!==n.mateRecordNumber&&n.mateRecordNumber!==t);r.readName||(r.readName=String(r.uniqueId),n.readName=r.readName),r.mate={sequenceId:n.sequenceId,alignmentStart:n.alignmentStart,uniqueId:n.uniqueId},n.readName&&(r.mate.readName=n.readName),n.mate||void 0!==n.mateRecordNumber||(n.mate={sequenceId:r.sequenceId,alignmentStart:r.alignmentStart,uniqueId:r.uniqueId},r.readName&&(n.mate.readName=r.readName)),r.flags|=s.default.BAM_FPAIRED,n.flags&s.default.BAM_FUNMAP&&(r.flags|=s.default.BAM_FMUNMAP),r.flags&s.default.BAM_FUNMAP&&(n.flags|=s.default.BAM_FMUNMAP),n.flags&s.default.BAM_FREVERSE&&(r.flags|=s.default.BAM_FMREVERSE),r.flags&s.default.BAM_FREVERSE&&(n.flags|=s.default.BAM_FMREVERSE),void 0===r.templateLength&&(i?function(e,t,r){const n=function t(r){const n=[r];if(void 0!==r.mateRecordNumber&&r.mateRecordNumber>=0){const i=e[r.mateRecordNumber];if(!i)throw new a.CramMalformedError("intra-slice mate record not found, this file seems malformed");n.push(...t(i))}return n}(r),i=n.map(e=>e.alignmentStart),s=n.map(e=>e.alignmentStart+e.readLength-1),A=Math.max(...s)-Math.min(...i)+1;A>=0&&n.forEach(e=>{if(void 0!==e.templateLength)throw new a.CramMalformedError("mate pair group has some members that have template lengths already, this file seems malformed");e.templateLength=A})}(e,0,r):function(e,t){const r=Math.min(e.alignmentStart,t.alignmentStart),n=Math.max(e.alignmentStart+e.readLength-1,t.alignmentStart+t.readLength-1)-r+1;e.templateLength=n,t.templateLength=n}(r,n)),r.mateRecordNumber=void 0}class f{constructor(e,t,r){this.container=e,this.containerPosition=t,this.sliceSize=r,this.file=e.file}async getHeader(){const{majorVersion:e}=await this.file.getDefinition(),t=(0,c.getSectionParsers)(e),r=await this.container.getHeader(),n=await this.file.readBlock(r._endPosition+this.containerPosition);if("MAPPED_SLICE_HEADER"===n.contentType){const e=(0,d.parseItem)(n.content,t.cramMappedSliceHeader.parser,0,r._endPosition);return{...n,parsedContent:e}}if("UNMAPPED_SLICE_HEADER"===n.contentType){const e=(0,d.parseItem)(n.content,t.cramUnmappedSliceHeader.parser,0,r._endPosition);return{...n,parsedContent:e}}throw new a.CramMalformedError(`error reading slice header block, invalid content type ${n.contentType}`)}async getBlocks(){const e=await this.getHeader();let t=e._endPosition;const r=new Array(e.parsedContent.numBlocks);for(let e=0;e<r.length;e++){const n=await this.file.readBlock(t);r[e]=n,t=r[e]._endPosition}return r}async getCoreDataBlock(){return(await this.getBlocks())[0]}async _getBlocksContentIdIndex(){const e=await this.getBlocks(),t={};return e.forEach(e=>{"EXTERNAL_DATA"===e.contentType&&(t[e.contentId]=e)}),t}async getBlockByContentId(e){return(await this._getBlocksContentIdIndex())[e]}async getReferenceRegion(){const e=new TextDecoder("utf8"),t=(await this.getHeader()).parsedContent;if(!(0,c.isMappedSliceHeader)(t))throw new Error("slice header not mapped");if(t.refSeqId<0)return;const r=await this.container.getCompressionScheme();if(void 0===r)throw new Error("compression scheme undefined");if(t.refBaseBlockId>=0){const r=await this.getBlockByContentId(t.refBaseBlockId);if(!r)throw new a.CramMalformedError("embedded reference specified, but reference block does not exist");return{seq:e.decode(r.data),start:t.refSeqStart,end:t.refSeqStart+t.refSeqSpan-1,span:t.refSeqSpan}}if(r.referenceRequired||this.file.fetchReferenceSequenceCallback){if(!this.file.fetchReferenceSequenceCallback)throw new Error("reference sequence not embedded, and seqFetch callback not provided, cannot fetch reference sequence");const e=await this.file.fetchReferenceSequenceCallback(t.refSeqId,t.refSeqStart,t.refSeqStart+t.refSeqSpan-1);if(e.length!==t.refSeqSpan)throw new a.CramArgumentError("seqFetch callback returned a reference sequence of the wrong length");return{seq:e,start:t.refSeqStart,end:t.refSeqStart+t.refSeqSpan-1,span:t.refSeqSpan}}}getAllRecords(){return this.getRecords(()=>!0)}async _fetchRecords(){const{majorVersion:e}=await this.file.getDefinition(),t=await this.container.getCompressionScheme();if(void 0===t)throw new Error("compression scheme undefined");const r=await this.getHeader(),n=await this._getBlocksContentIdIndex();if(e>1&&this.file.options.checkSequenceMD5&&(0,c.isMappedSliceHeader)(r.parsedContent)&&r.parsedContent.refSeqId>=0&&"0000000000000000"!==r.parsedContent.md5?.join("")){const e=await this.getReferenceRegion();if(e){const{seq:t,start:n,end:i}=e,s=(0,d.sequenceMD5)(t),A=r.parsedContent.md5?.map(e=>(e<16?"0":"")+e.toString(16)).join("");if(s!==A)throw new a.CramMalformedError(`MD5 checksum reference mismatch for ref ${r.parsedContent.refSeqId} pos ${n}..${i}. recorded MD5: ${A}, calculated MD5: ${s}`)}}const s=await this.getCoreDataBlock(),f={lastAlignmentStart:(0,c.isMappedSliceHeader)(r.parsedContent)?r.parsedContent.refSeqStart:0,coreBlock:{bitPosition:7,bytePosition:0},externalBlocks:{map:new Map,getCursor(e){let t=this.map.get(e);return void 0===t&&(t={bitPosition:7,bytePosition:0},this.map.set(e,t)),t}}},u=e=>{const r=t.getCodecForDataSeries(e);if(!r)throw new a.CramMalformedError(`no codec defined for ${e} data series`);return r.decode(this,s,n,f)},h=new Array(r.parsedContent.numRecords);for(let a=0;a<h.length;a+=1)try{const i=(0,A.default)(this,u,t,r,s,n,f,e,a);h[a]=new o.default({...i,uniqueId:r.contentPosition+r.parsedContent.recordCounter+a+1})}catch(e){if(e instanceof i.CramBufferOverrunError){console.warn("read attempted beyond end of buffer, file seems truncated.");break}throw e}for(let e=0;e<h.length;e+=1){const t=h[e];if(t){const{mateRecordNumber:r}=t;void 0!==r&&r>=0&&h[r]&&l(h,e,t,h[r])}}return h}async getRecords(e){const t=this.container.filePosition+this.containerPosition;let 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n=this.reader,a=n.pi();if("177245385090"===a)return!1;"314159265359"!==a&&d(o.NOT_BZIP_DATA),this.targetBlockCRC=n.read(32)>>>0,this.streamCRC=(this.targetBlockCRC^(this.streamCRC<<1|this.streamCRC>>>31))>>>0,n.read(1)&&d(o.OBSOLETE_INPUT);const i=n.read(24);i>this.dbufSize&&d(o.DATA_ERROR,"initial position out of bounds");let s=n.read(16),c=new Uint8Array(256),l=0;for(e=0;e<16;e++)if(s&1<<15-e){const a=16*e;for(r=n.read(16),t=0;t<16;t++)r&1<<15-t&&(c[l++]=a+t)}const f=n.read(3);(f<2||f>6)&&d(o.DATA_ERROR);const u=n.read(15);0===u&&d(o.DATA_ERROR);const h=new Uint8Array(256);for(e=0;e<f;e++)h[e]=e;const g=new Uint8Array(u);for(e=0;e<u;e++){for(t=0;n.read(1);t++)t>=f&&d(o.DATA_ERROR);g[e]=A(h,t)}let C,I=l+2,_=[];for(t=0;t<f;t++){const t=new Uint8Array(I),r=new Uint16Array(21);for(s=n.read(5),e=0;e<I;e++){for(;(s<1||s>20)&&d(o.DATA_ERROR),n.read(1);)n.read(1)?s--:s++;t[e]=s}var B,m;for(B=m=t[0],e=1;e<I;e++)t[e]>m?m=t[e]:t[e]<B&&(B=t[e]);C={},_.push(C),C.permute=new 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w||(w=1,s=0),s+=0===r?w:2*w,w<<=1}for((i<0||i>=Q)&&d(o.DATA_ERROR),t=0,e=0;e<256;e++)r=t+p[e],p[e]=t,t=r;for(e=0;e<Q;e++)E=255&b[e],b[p[E]]|=e<<8,p[E]++;let S=0,R=0,D=0;return Q&&(S=b[i],R=255&S,S>>=8,D=-1),this.writePos=S,this.writeCurrent=R,this.writeCount=Q,this.writeRun=D,!0}_read_bunzip(e,t){let r,n,a;if(this.writeCount<0)return 0;let i=this.dbuf,s=this.writePos,A=this.writeCurrent,c=this.writeCount,l=(this.outputsize,this.writeRun);for(;c;){for(c--,n=A,s=i[s],A=255&s,s>>=8,3===l++?(r=A,a=n,A=-1):(r=1,a=A),this.blockCRC.updateCRCRun(a,r);r--;)this.outputStream.writeByte(a),this.nextoutput++;A!=n&&(l=0)}return this.writeCount=c,this.blockCRC.getCRC()!==this.targetBlockCRC&&d(o.DATA_ERROR,"Bad block CRC (got "+this.blockCRC.getCRC().toString(16)+" expected "+this.targetBlockCRC.toString(16)+")"),this.nextoutput}}const f=function(e){if("readByte"in e)return e;const t=new s.default;return t.pos=0,t.readByte=function(){return 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1:return function(e,t){const r=new Array(256);for(let e=0;e<r.length;e+=1)r[e]=new A.default.AriDecoder;const n=new Array(256);for(let e=0;e<n.length;e+=1){n[e]=new Array(256);for(let t=0;t<n[e].length;t+=1)n[e][t]=new A.default.DecodingSymbol}return(0,o.readStatsO1)(e,r,n),(0,s.default)(e,t,r,n),t}(n,u);default:throw new a.CramMalformedError(`Invalid rANS order: ${l}`)}};const a=r(6272),i=n(r(1558)),s=n(r(2867)),A=n(r(9301)),o=r(6268),c=4;class d{constructor(e,t=0){this._buffer=e,this._dataView=new DataView(e.buffer),this._position=t,this.length=e.length}get(){const e=this._buffer[this._position];return this._position+=1,e}getByte(){return this.get()}getByteAt(e){return this._buffer[e]}position(){return this._position}put(e){return this._buffer[this._position]=e,this._position+=1,e}putAt(e,t){return this._buffer[e]=t,t}setPosition(e){return this._position=e,e}getInt(){const e=this._dataView.getInt32(this._position,!0);return this._position+=4,e}remaining(){return this._buffer.length-this._position}}},2845:function(e,t,r){"use strict";var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const a=r(6272),i=n(r(500)),s=r(2549),A=n(r(8700)),o=r(7580);class c{constructor(e,t){this.file=e,this.filePosition=t}getHeader(){return this._readContainerHeader(this.filePosition)}async getCompressionHeaderBlock(){if(!(await this.getHeader()).numRecords)return null;const{majorVersion:e}=await this.file.getDefinition(),t=(0,o.getSectionParsers)(e),r=await this.getFirstBlock();if("COMPRESSION_HEADER"!==r.contentType)throw new a.CramMalformedError(`invalid content type ${r.contentType} in compression header block`);const n=(0,s.parseItem)(r.content,t.cramCompressionHeader.parser,0,r.contentPosition);return{...r,parsedContent:n}}async getFirstBlock(){const e=await this.getHeader();return this.file.readBlock(e._endPosition)}async getCompressionScheme(){const e=await this.getCompressionHeaderBlock();if(e)return new A.default(e.parsedContent)}getSlice(e,t){return new i.default(this,e,t)}async _readContainerHeader(e){const{majorVersion:t}=await this.file.getDefinition(),r=(0,o.getSectionParsers)(t),{cramContainerHeader1:n,cramContainerHeader2:a}=r,i=await this.file.read(n.maxLength,e),A=(0,s.parseItem)(i,n.parser),c=(0,s.itf8Size)(A.numLandmarks),d=await this.file.read(a.maxLength(A.numLandmarks),e+A._size-c),l=(0,s.parseItem)(d,a.parser);return this.file.validateChecksums&&void 0!==l.crc32&&await this.file.checkCrc32(e,A._size+l._size-c-4,l.crc32,`container header beginning at position ${e}`),{...A,...l,_size:A._size+l._size-c,_endPosition:A._size+l._size-c+e}}}t.default=c,"getHeader getCompressionHeaderBlock getCompressionScheme".split(" ").forEach(e=>{(0,s.tinyMemoize)(c,e)})},2867:function(e,t,r){"use strict";var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.default=function(e,t,r,n){const s=t.remaining();let A=e.getInt(),o=e.getInt(),c=e.getInt(),d=e.getInt();const l=s>>2;let f=0,u=l,h=2*l,g=3*l,C=0,I=0,_=0,B=0;for(;f<l;f+=1,u+=1,h+=1,g+=1){const s=255&r[C].R[i.default.get(A,a.TF_SHIFT)],l=255&r[I].R[i.default.get(o,a.TF_SHIFT)],m=255&r[_].R[i.default.get(c,a.TF_SHIFT)],p=255&r[B].R[i.default.get(d,a.TF_SHIFT)];t.putAt(f,s),t.putAt(u,l),t.putAt(h,m),t.putAt(g,p),A=i.default.advanceSymbolStep(A,n[C][s],a.TF_SHIFT),o=i.default.advanceSymbolStep(o,n[I][l],a.TF_SHIFT),c=i.default.advanceSymbolStep(c,n[_][m],a.TF_SHIFT),d=i.default.advanceSymbolStep(d,n[B][p],a.TF_SHIFT),A=i.default.renormalize(A,e),o=i.default.renormalize(o,e),c=i.default.renormalize(c,e),d=i.default.renormalize(d,e),C=s,I=l,_=m,B=p}for(;g<s;g+=1){const s=255&r[B].R[i.default.get(d,a.TF_SHIFT)];t.putAt(g,s),d=i.default.advanceSymbol(d,e,n[B][s],a.TF_SHIFT),B=s}};const a=r(7151),i=n(r(9301))},3088:(e,t)=>{"use strict";Object.defineProperty(t,"__esModule",{value:!0}),t.default=class{constructor(e,t=0,r=0){0!==r?(this.buf=new Uint8Array(r),this.length=r):(this.buf=e,this.length=e.length),this.dataView=new DataView(this.buf.buffer),this.pos=t}EOF(){return this.pos>=this.length}ReadData(e){const t=this.buf.slice(this.pos,this.pos+e);return this.pos+=e,t}ReadByte(){const e=this.buf[this.pos];return this.pos++,e}ReadChar(){const e=this.buf[this.pos];return this.pos++,String.fromCharCode(e)}ReadUint16(){let e=this.ReadByte();return e|=this.ReadByte()<<8,e}ReadUint32(){const e=this.dataView.getInt32(this.pos,!0);return this.pos+=4,e}ReadString(){let e,t="";do{e=this.buf[this.pos++],e&&(t+=String.fromCharCode(e))}while(e);return t}ReadUint7(){let e,t=0;do{e=this.ReadByte(),t=t<<7|127&e}while(128&e);return t}ReadITF8(){let e=this.buf[this.pos];return this.pos++,e>=240?(e=(15&e)<<28,e+=(this.buf[this.pos+0]<<20)+(this.buf[this.pos+1]<<12)+(this.buf[this.pos+2]<<4)+(this.buf[this.pos+3]>>4),this.pos+=4):e>=224?(e=(15&e)<<24,e+=(this.buf[this.pos+0]<<16)+(this.buf[this.pos+1]<<8)+(0|this.buf[this.pos+2]),this.pos+=3):e>=192?(e=(31&e)<<16,e+=(this.buf[this.pos+0]<<8)+(0|this.buf[this.pos+1]),this.pos+=2):e>=128&&(e=(63&e)<<8,e+=this.buf[this.pos],this.pos++),e}}},3503:(e,t,r)=>{var n,a,i,s,A;n=r(3939),a=r(2151).utf8,i=r(652),s=r(2151).bin,(A=function(e,t){e.constructor==String?e=t&&"binary"===t.encoding?s.stringToBytes(e):a.stringToBytes(e):i(e)?e=Array.prototype.slice.call(e,0):Array.isArray(e)||e.constructor===Uint8Array||(e=e.toString());for(var r=n.bytesToWords(e),o=8*e.length,c=1732584193,d=-271733879,l=-1732584194,f=271733878,u=0;u<r.length;u++)r[u]=16711935&(r[u]<<8|r[u]>>>24)|4278255360&(r[u]<<24|r[u]>>>8);r[o>>>5]|=128<<o%32,r[14+(o+64>>>9<<4)]=o;var h=A._ff,g=A._gg,C=A._hh,I=A._ii;for(u=0;u<r.length;u+=16){var _=c,B=d,m=l,p=f;c=h(c,d,l,f,r[u+0],7,-680876936),f=h(f,c,d,l,r[u+1],12,-389564586),l=h(l,f,c,d,r[u+2],17,606105819),d=h(d,l,f,c,r[u+3],22,-1044525330),c=h(c,d,l,f,r[u+4],7,-176418897),f=h(f,c,d,l,r[u+5],12,1200080426),l=h(l,f,c,d,r[u+6],17,-1473231341),d=h(d,l,f,c,r[u+7],22,-45705983),c=h(c,d,l,f,r[u+8],7,1770035416),f=h(f,c,d,l,r[u+9],12,-1958414417),l=h(l,f,c,d,r[u+10],17,-42063),d=h(d,l,f,c,r[u+11],22,-1990404162),c=h(c,d,l,f,r[u+12],7,1804603682),f=h(f,c,d,l,r[u+13],12,-40341101),l=h(l,f,c,d,r[u+14],17,-1502002290),c=g(c,d=h(d,l,f,c,r[u+15],22,1236535329),l,f,r[u+1],5,-165796510),f=g(f,c,d,l,r[u+6],9,-1069501632),l=g(l,f,c,d,r[u+11],14,643717713),d=g(d,l,f,c,r[u+0],20,-373897302),c=g(c,d,l,f,r[u+5],5,-701558691),f=g(f,c,d,l,r[u+10],9,38016083),l=g(l,f,c,d,r[u+15],14,-660478335),d=g(d,l,f,c,r[u+4],20,-405537848),c=g(c,d,l,f,r[u+9],5,568446438),f=g(f,c,d,l,r[u+14],9,-1019803690),l=g(l,f,c,d,r[u+3],14,-187363961),d=g(d,l,f,c,r[u+8],20,1163531501),c=g(c,d,l,f,r[u+13],5,-1444681467),f=g(f,c,d,l,r[u+2],9,-51403784),l=g(l,f,c,d,r[u+7],14,1735328473),c=C(c,d=g(d,l,f,c,r[u+12],20,-1926607734),l,f,r[u+5],4,-378558),f=C(f,c,d,l,r[u+8],11,-2022574463),l=C(l,f,c,d,r[u+11],16,1839030562),d=C(d,l,f,c,r[u+14],23,-35309556),c=C(c,d,l,f,r[u+1],4,-1530992060),f=C(f,c,d,l,r[u+4],11,1272893353),l=C(l,f,c,d,r[u+7],16,-155497632),d=C(d,l,f,c,r[u+10],23,-1094730640),c=C(c,d,l,f,r[u+13],4,681279174),f=C(f,c,d,l,r[u+0],11,-358537222),l=C(l,f,c,d,r[u+3],16,-722521979),d=C(d,l,f,c,r[u+6],23,76029189),c=C(c,d,l,f,r[u+9],4,-640364487),f=C(f,c,d,l,r[u+12],11,-421815835),l=C(l,f,c,d,r[u+15],16,530742520),c=I(c,d=C(d,l,f,c,r[u+2],23,-995338651),l,f,r[u+0],6,-198630844),f=I(f,c,d,l,r[u+7],10,1126891415),l=I(l,f,c,d,r[u+14],15,-1416354905),d=I(d,l,f,c,r[u+5],21,-57434055),c=I(c,d,l,f,r[u+12],6,1700485571),f=I(f,c,d,l,r[u+3],10,-1894986606),l=I(l,f,c,d,r[u+10],15,-1051523),d=I(d,l,f,c,r[u+1],21,-2054922799),c=I(c,d,l,f,r[u+8],6,1873313359),f=I(f,c,d,l,r[u+15],10,-30611744),l=I(l,f,c,d,r[u+6],15,-1560198380),d=I(d,l,f,c,r[u+13],21,1309151649),c=I(c,d,l,f,r[u+4],6,-145523070),f=I(f,c,d,l,r[u+11],10,-1120210379),l=I(l,f,c,d,r[u+2],15,718787259),d=I(d,l,f,c,r[u+9],21,-343485551),c=c+_>>>0,d=d+B>>>0,l=l+m>>>0,f=f+p>>>0}return n.endian([c,d,l,f])})._ff=function(e,t,r,n,a,i,s){var A=e+(t&r|~t&n)+(a>>>0)+s;return(A<<i|A>>>32-i)+t},A._gg=function(e,t,r,n,a,i,s){var A=e+(t&n|r&~n)+(a>>>0)+s;return(A<<i|A>>>32-i)+t},A._hh=function(e,t,r,n,a,i,s){var A=e+(t^r^n)+(a>>>0)+s;return(A<<i|A>>>32-i)+t},A._ii=function(e,t,r,n,a,i,s){var A=e+(r^(t|~n))+(a>>>0)+s;return(A<<i|A>>>32-i)+t},A._blocksize=16,A._digestsize=16,e.exports=function(e,t){if(null==e)throw new Error("Illegal argument "+e);var r=n.wordsToBytes(A(e,t));return t&&t.asBytes?r:t&&t.asString?s.bytesToString(r):n.bytesToHex(r)}},3939:e=>{var t,r;t="ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+/",r={rotl:function(e,t){return e<<t|e>>>32-t},rotr:function(e,t){return e<<32-t|e>>>t},endian:function(e){if(e.constructor==Number)return 16711935&r.rotl(e,8)|4278255360&r.rotl(e,24);for(var t=0;t<e.length;t++)e[t]=r.endian(e[t]);return e},randomBytes:function(e){for(var t=[];e>0;e--)t.push(Math.floor(256*Math.random()));return t},bytesToWords:function(e){for(var t=[],r=0,n=0;r<e.length;r++,n+=8)t[n>>>5]|=e[r]<<24-n%32;return t},wordsToBytes:function(e){for(var t=[],r=0;r<32*e.length;r+=8)t.push(e[r>>>5]>>>24-r%32&255);return t},bytesToHex:function(e){for(var t=[],r=0;r<e.length;r++)t.push((e[r]>>>4).toString(16)),t.push((15&e[r]).toString(16));return t.join("")},hexToBytes:function(e){for(var t=[],r=0;r<e.length;r+=2)t.push(parseInt(e.substr(r,2),16));return t},bytesToBase64:function(e){for(var r=[],n=0;n<e.length;n+=3)for(var a=e[n]<<16|e[n+1]<<8|e[n+2],i=0;i<4;i++)8*n+6*i<=8*e.length?r.push(t.charAt(a>>>6*(3-i)&63)):r.push("=");return r.join("")},base64ToBytes:function(e){e=e.replace(/[^A-Z0-9+\/]/gi,"");for(var r=[],n=0,a=0;n<e.length;a=++n%4)0!=a&&r.push((t.indexOf(e.charAt(n-1))&Math.pow(2,-2*a+8)-1)<<2*a|t.indexOf(e.charAt(n))>>>6-2*a);return r}},e.exports=r},4056:function(e,t,r){"use strict";var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const a=n(r(4141)),i=r(6761),s=r(6272);class A extends a.default{constructor(e,t){if(super(e,t),this.codes={},this.codeBook={},this.sortedCodes=[],this.sortedValuesByBitCode=[],this.sortedBitCodes=[],this.sortedBitLengthsByBitCode=[],this.bitCodeToValue=[],!["byte","int"].includes(this.dataType))throw new TypeError(`${this.dataType} decoding not yet implemented by HUFFMAN_INT codec`);this.buildCodeBook(),this.buildCodes(),this.buildCaches(),0===this.sortedCodes[0].bitLength&&(this._decode=this._decodeZeroLengthCode)}buildCodeBook(){let e=new Array(this.parameters.numCodes);for(let t=0;t<this.parameters.numCodes;t++)e[t]={symbol:this.parameters.symbols[t],bitLength:this.parameters.bitLengths[t]};e=e.sort((e,t)=>e.bitLength-t.bitLength||e.symbol-t.symbol),this.codeBook={},e.forEach(e=>{this.codeBook[e.bitLength]||(this.codeBook[e.bitLength]=[]),this.codeBook[e.bitLength].push(e.symbol)})}buildCodes(){this.codes={};let e=0,t=-1;Object.entries(this.codeBook).forEach(([r,n])=>{const a=Number.parseInt(r,10);n.forEach(r=>{const n={bitLength:a,value:r,bitCode:0};t+=1;const i=a-e;if(t<<=i,n.bitCode=t,e+=i,function(e){let t=e-(e>>1)&1431655765;return t=(858993459&t)+(t>>2&858993459),16843009*(t+(t>>4)&252645135)>>24}(t)>a)throw new s.CramMalformedError("Symbol out of 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mismatch in ${n}: recorded CRC32 = ${r}, but calculated CRC32 = ${i}`)}async containerCount(){const{majorVersion:e}=await this.getDefinition();let t=0,r=(0,B.getSectionParsers)(e).cramFileDefinition.maxLength;try{for(;;){const e=await this.getContainerAtPosition(r).getHeader();if(0===t){r=e._endPosition;for(let t=0;t<e.numBlocks;t++)r=(await this.readBlock(r))._endPosition}else r+=e._size+e.length;t+=1}}catch(e){t--}return t}getContainerAtPosition(e){return new _.default(this,e)}async readBlockHeader(e){const{majorVersion:t}=await this.getDefinition(),r=(0,B.getSectionParsers)(t),{cramBlockHeader:n}=r,a=await this.file.read(n.maxLength,e);return(0,m.parseItem)(a,n.parser,0,e)}async _parseSection(e,t,r=e.maxLength,n){const a=n??await this.file.read(r,t),i=(0,m.parseItem)(a,e.parser,0,t);if(i._size!==r)throw new l.CramMalformedError(`section read error: requested size ${r} does not equal parsed size ${i._size}`);return i}async _uncompressPre(e,t,r){if("gzip"===e)return(0,I.unzip)(t);if("bzip2"===e)return(0,C.decode)(t);if("lzma"===e){const e=new Response(new d.XzReadableStream((n=t,new ReadableStream({start(e){e.enqueue(n),e.close()}}))));return new Uint8Array(await e.arrayBuffer())}if("rans"===e){const e=new Uint8Array(r);return(0,h.default)(t,e),e}if("rans4x16"===e)return f.r4x16_uncompress(t);if("arith"===e)return f.arith_uncompress(t);if("fqzcomp"===e)return f.fqzcomp_uncompress(t);if("tok3"===e)return f.tok3_uncompress(t);throw new l.CramUnimplementedError(`${e} decompression not yet implemented`);var n}async _uncompress(e,t,r){const n=await this._uncompressPre(e,t,r);if(n.length!==r){const e=new Uint8Array(r);return e.set(n,0),e}return n}async readBlock(e){const{majorVersion:t}=await this.getDefinition(),r=(0,B.getSectionParsers)(t),n=await this.readBlockHeader(e),a=n._endPosition,i=await this.file.read(n.compressedSize,a),s="raw"!==n.compressionMethod?await this._uncompress(n.compressionMethod,i,n.uncompressedSize):i,A={...n,_endPosition:a,contentPosition:a,content:s};if(t>=3){const t=await this._parseSection(r.cramBlockCrc32,a+n.compressedSize);A.crc32=t.crc32,this.validateChecksums&&await this.checkCrc32(e,n._size+n.compressedSize,t.crc32,"block data"),A._endPosition=t._endPosition,A._size=A.compressedSize+r.cramBlockCrc32.maxLength}else A._endPosition=a+A.compressedSize,A._size=A.compressedSize;return A}}t.default=p,"getDefinition getSectionParsers getSamHeader".split(" ").forEach(e=>{(0,m.tinyMemoize)(p,e)})},8761:(e,t)=>{"use strict";Object.defineProperty(t,"__esModule",{value:!0});const r=new 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>0;)this.crc=this.crc<<8^r[255&(this.crc>>>24^e)]}}},8930:function(e,t,r){"use strict";var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const a=n(r(4141)),i=r(6272),s=r(2549),A=r(6761);class o extends a.default{constructor(e,t){if(super(e,t),"int"===this.dataType)this._decodeData=this._decodeInt;else{if("byte"!==this.dataType)throw new i.CramUnimplementedError(`${this.dataType} decoding not yet implemented by EXTERNAL codec`);this._decodeData=this._decodeByte}}decode(e,t,r,n){const{blockContentId:a}=this.parameters,i=r[a];return i?this._decodeData(i,n.externalBlocks.getCursor(a)):void 0}_decodeInt(e,t){const[r,n]=(0,s.parseItf8)(e.content,t.bytePosition);return t.bytePosition=t.bytePosition+n,r}_decodeByte(e,t){if(t.bytePosition>=e.content.length)throw new A.CramBufferOverrunError("attempted to read beyond end of block. this file seems truncated.");return e.content[t.bytePosition++]}}t.default=o},9301:(e,t,r)=>{"use strict";Object.defineProperty(t,"__esModule",{value:!0});const n=r(6272),a=r(7151);class i{constructor(){this.F=void 0,this.C=void 0}}function s(e,t,r,n){return r*(e>>n)+(e&(1<<n)-1)-t}t.default={FC:i,AriDecoder:class{constructor(){this.fc=new Array(256);for(let e=0;e<this.fc.length;e+=1)this.fc[e]=new i;this.R=null}},DecodingSymbol:class{constructor(){this.start=void 0,this.freq=void 0}},symbolInit:function(e,t,r){if(!(t<=65536))throw new n.CramMalformedError("assertion failed: start <= 1<<16");if(!(r<=65536-t))throw new n.CramMalformedError("assertion failed: freq <= 1<<16");e.start=t,e.freq=r},advanceStep:s,advanceSymbolStep:function(e,t,r){return s(e,t.start,t.freq,r)},get:function(e,t){return e&(1<<t)-1},advanceSymbol:function(e,t,r,n){return function(e,t,r,n,i){if((e=n*(e>>i)+(e&(1<<i)-1)-r)<a.RANS_BYTE_L)do{e=e<<8|255&t.get()}while(e<a.RANS_BYTE_L);return e}(e,t,r.start,r.freq,n)},renormalize:function(e,t){if(e<a.RANS_BYTE_L)do{e=e<<8|255&t.get()}while(e<a.RANS_BYTE_L);return e}}},9313:function(e,t,r){"use strict";var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.decode=function(e){return d(new a.default(e),0)};const a=n(r(3088));function i(e,t){return e&(1<<t)-1}function s(e,t){let r=0;for(;t>=e[r+1];)r++;return r}function A(e,t){const r=1<<t,n=new Array(r);let a=0;for(let t=0;t<r;t++){for(;t>=e[a+1];)a++;n[t]=a}return n}function o(e,t,r,n){return r*(e>>n)+(e&(1<<n)-1)-t}function c(e,t){return t<32768&&(t=(t<<16)+e.ReadUint16()),t}function d(e,t){const r=e.ReadByte(),n=1&r,h=8&r,g=32&r,C=64&r,I=128&r,_=4&r?32:4;if(16&r||(t=e.ReadUint7()),h)return function(e,t){const r=e.ReadByte(),n=new Array(r),a=new Array(r);for(var i=0;i<r;i++)n[i]=e.ReadUint7();const s=new Array(r);for(i=0;i<r;i++)a[i]=Math.floor(t/r)+(t%r>i),s[i]=d(e,a[i]);const A=new 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128&r&&(s=this.decodePack(s,i,t)),s}decode0(e,t){const r=new Uint8Array(t);let n=e.ReadByte();0==n&&(n=256);const a=new s.default(n),A=new i.default(e);A.RangeStartDecode(e);for(let n=0;n<t;n++)r[n]=a.ModelDecode(e,A);return r}decode1(e,t){const r=new Uint8Array(t);let n=e.ReadByte();0==n&&(n=256);const a=new Array(n);for(var A=0;A<n;A++)a[A]=new s.default(n);const o=new i.default(e);o.RangeStartDecode(e);let c=0;for(A=0;A<t;A++)r[A]=a[c].ModelDecode(e,o),c=r[A];return r}decodeExt(e,t){return(0,a.decode)(e.buf.slice(e.pos))}decodeRLE0(e,t){const r=new Uint8Array(t);let n=e.ReadByte();0==n&&(n=256);const a=new s.default(n),A=new Array(258);for(var o=0;o<=257;o++)A[o]=new s.default(4);const c=new i.default(e);for(c.RangeStartDecode(e),o=0;o<t;){r[o]=a.ModelDecode(e,c);let t=A[r[o]].ModelDecode(e,c),n=t,i=256;for(;3==t;)t=A[i].ModelDecode(e,c),i=257,n+=t;for(let e=1;e<=n;e++)r[o+e]=r[o];o+=n+1}return r}decodeRLE1(e,t){const r=new Uint8Array(t);let n=e.ReadByte();0==n&&(n=256);const a=new 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n}(r),a=n.map(e=>e.alignmentStart),s=n.map(e=>e.alignmentStart+e.readLength-1),A=Math.max(...s)-Math.min(...a)+1;A>=0&&n.forEach(e=>{if(void 0!==e.templateLength)throw new i.CramMalformedError("mate pair group has some members that have template lengths already, this file seems malformed");e.templateLength=A})}(e,0,r):function(e,t){const r=Math.min(e.alignmentStart,t.alignmentStart),n=Math.max(e.alignmentStart+e.readLength-1,t.alignmentStart+t.readLength-1)-r+1;e.templateLength=n,t.templateLength=n}(r,n)),r.mateRecordNumber=void 0}class f{constructor(e,t,r){this.container=e,this.containerPosition=t,this.sliceSize=r,this.file=e.file}async getHeader(){const{majorVersion:e}=await this.file.getDefinition(),t=(0,c.getSectionParsers)(e),r=await this.container.getHeader(),n=await this.file.readBlock(r._endPosition+this.containerPosition);if("MAPPED_SLICE_HEADER"===n.contentType){const e=(0,d.parseItem)(n.content,t.cramMappedSliceHeader.parser,0,r._endPosition);return{...n,parsedContent:e}}if("UNMAPPED_SLICE_HEADER"===n.contentType){const e=(0,d.parseItem)(n.content,t.cramUnmappedSliceHeader.parser,0,r._endPosition);return{...n,parsedContent:e}}throw new i.CramMalformedError(`error reading slice header block, invalid content type ${n.contentType}`)}async getBlocks(){const e=await this.getHeader();let t=e._endPosition;const r=new Array(e.parsedContent.numBlocks);for(let e=0;e<r.length;e++){const n=await this.file.readBlock(t);r[e]=n,t=r[e]._endPosition}return r}async getCoreDataBlock(){return(await this.getBlocks())[0]}async _getBlocksContentIdIndex(){const e=await this.getBlocks(),t={};return e.forEach(e=>{"EXTERNAL_DATA"===e.contentType&&(t[e.contentId]=e)}),t}async getBlockByContentId(e){return(await this._getBlocksContentIdIndex())[e]}async getReferenceRegion(){const e=new TextDecoder("utf8"),t=(await this.getHeader()).parsedContent;if(!(0,c.isMappedSliceHeader)(t))throw new Error("slice header not mapped");if(t.refSeqId<0)return;const r=await this.container.getCompressionScheme();if(void 0===r)throw new Error("compression scheme undefined");if(t.refBaseBlockId>=0){const r=await this.getBlockByContentId(t.refBaseBlockId);if(!r)throw new i.CramMalformedError("embedded reference specified, but reference block does not exist");return{seq:e.decode(r.data),start:t.refSeqStart,end:t.refSeqStart+t.refSeqSpan-1,span:t.refSeqSpan}}if(r.referenceRequired||this.file.fetchReferenceSequenceCallback){if(!this.file.fetchReferenceSequenceCallback)throw new Error("reference sequence not embedded, and seqFetch callback not provided, cannot fetch reference sequence");const e=await this.file.fetchReferenceSequenceCallback(t.refSeqId,t.refSeqStart,t.refSeqStart+t.refSeqSpan-1);if(e.length!==t.refSeqSpan)throw new i.CramArgumentError("seqFetch callback returned a reference sequence of the wrong length");return{seq:e,start:t.refSeqStart,end:t.refSeqStart+t.refSeqSpan-1,span:t.refSeqSpan}}}getAllRecords(){return this.getRecords(()=>!0)}async _fetchRecords(){const{majorVersion:e}=await this.file.getDefinition(),t=await this.container.getCompressionScheme();if(void 0===t)throw new Error("compression scheme undefined");const r=await this.getHeader(),n=await this._getBlocksContentIdIndex();if(e>1&&this.file.options.checkSequenceMD5&&(0,c.isMappedSliceHeader)(r.parsedContent)&&r.parsedContent.refSeqId>=0&&"0000000000000000"!==r.parsedContent.md5?.join("")){const e=await this.getReferenceRegion();if(e){const{seq:t,start:n,end:a}=e,s=(0,d.sequenceMD5)(t),A=r.parsedContent.md5?.map(e=>(e<16?"0":"")+e.toString(16)).join("");if(s!==A)throw new i.CramMalformedError(`MD5 checksum reference mismatch for ref ${r.parsedContent.refSeqId} pos ${n}..${a}. recorded MD5: ${A}, calculated MD5: ${s}`)}}const s=await this.getCoreDataBlock(),f={lastAlignmentStart:(0,c.isMappedSliceHeader)(r.parsedContent)?r.parsedContent.refSeqStart:0,coreBlock:{bitPosition:7,bytePosition:0},externalBlocks:{map:new Map,getCursor(e){let t=this.map.get(e);return void 0===t&&(t={bitPosition:7,bytePosition:0},this.map.set(e,t)),t}}},u=new Map,h=e=>{let r=u.get(e);if(void 0===r){if(r=t.getCodecForDataSeries(e),!r)throw new i.CramMalformedError(`no codec defined for ${e} data series`);u.set(e,r)}return r.decode(this,s,n,f)},g=new Array(r.parsedContent.numRecords);for(let c=0;c<g.length;c+=1)try{const i=(0,A.default)(this,h,t,r,s,n,f,e,c);g[c]=new o.default({...i,uniqueId:r.contentPosition+r.parsedContent.recordCounter+c+1})}catch(e){if(e instanceof a.CramBufferOverrunError){const t=c,n=r.parsedContent.numRecords;throw new i.CramMalformedError(`Failed to decode all records in slice. Decoded ${t} of ${n} expected records. Buffer overrun suggests either: (1) file is truncated/corrupted, (2) compression scheme is incorrect, or (3) there's a bug in the decoder. 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a=e.alignmentStart+(e.lengthOnRef||e.readLength)-1;a>n.end&&(n.end=a),e.alignmentStart<n.start&&(n.start=e.alignmentStart)}await Promise.all(Object.values(i).map(async e=>{-1!==e.id&&e.start<=e.end&&this.file.fetchReferenceSequenceCallback&&(e.seq=await this.file.fetchReferenceSequenceCallback(e.id,e.start,e.end))}));for(const e of n){const n=i[void 0!==t?t:e.sequenceId];if(n?.seq){const t=n.seq;e.addReferenceSequence({...n,seq:t},r)}}}}return n}}t.default=f,"getHeader getBlocks _getBlocksContentIdIndex".split(" ").forEach(e=>{(0,d.tinyMemoize)(f,e)})},531:(e,t)=>{"use strict";Object.defineProperty(t,"__esModule",{value:!0}),t.default=function(e,t,r,n){for(var i=65535&e,a=e>>>16&65535,s=0;0!==r;){r-=s=r>2e3?2e3:r;do{a=a+(i=i+t[n++]|0)|0}while(--s);i%=65521,a%=65521}return i|a<<16}},588:(e,t)=>{"use 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n=this.reader,i=n.pi();if("177245385090"===i)return!1;"314159265359"!==i&&d(o.NOT_BZIP_DATA),this.targetBlockCRC=n.read(32)>>>0,this.streamCRC=(this.targetBlockCRC^(this.streamCRC<<1|this.streamCRC>>>31))>>>0,n.read(1)&&d(o.OBSOLETE_INPUT);const a=n.read(24);a>this.dbufSize&&d(o.DATA_ERROR,"initial position out of bounds");let s=n.read(16),c=new Uint8Array(256),l=0;for(e=0;e<16;e++)if(s&1<<15-e){const i=16*e;for(r=n.read(16),t=0;t<16;t++)r&1<<15-t&&(c[l++]=i+t)}const f=n.read(3);(f<2||f>6)&&d(o.DATA_ERROR);const u=n.read(15);0===u&&d(o.DATA_ERROR);const h=new Uint8Array(256);for(e=0;e<f;e++)h[e]=e;const g=new Uint8Array(u);for(e=0;e<u;e++){for(t=0;n.read(1);t++)t>=f&&d(o.DATA_ERROR);g[e]=A(h,t)}let C,I=l+2,_=[];for(t=0;t<f;t++){const t=new Uint8Array(I),r=new Uint16Array(21);for(s=n.read(5),e=0;e<I;e++){for(;(s<1||s>20)&&d(o.DATA_ERROR),n.read(1);)n.read(1)?s--:s++;t[e]=s}var B,m;for(B=m=t[0],e=1;e<I;e++)t[e]>m?m=t[e]:t[e]<B&&(B=t[e]);C={},_.push(C),C.permute=new Uint16Array(258),C.limit=new Uint32Array(22),C.base=new Uint32Array(21),C.minLen=B,C.maxLen=m;let i=0;for(e=B;e<=m;e++)for(r[e]=C.limit[e]=0,s=0;s<I;s++)t[s]===e&&(C.permute[i++]=s);for(e=0;e<I;e++)r[t[e]]++;for(i=s=0,e=B;e<m;e++)i+=r[e],C.limit[e]=i-1,i<<=1,s+=r[e],C.base[e+1]=i-s;C.limit[m+1]=Number.MAX_VALUE,C.limit[m]=i+r[m]-1,C.base[B]=0}const E=new Uint32Array(256);for(e=0;e<256;e++)h[e]=e;let p,w=0,Q=0,y=0;const b=this.dbuf=new Uint32Array(this.dbufSize);for(I=0;;){for(I--||(I=49,y>=u&&d(o.DATA_ERROR),C=_[g[y++]]),e=C.minLen,t=n.read(e);e>C.maxLen&&d(o.DATA_ERROR),!(t<=C.limit[e]);e++)t=t<<1|n.read(1);t-=C.base[e],(t<0||t>=258)&&d(o.DATA_ERROR);const r=C.permute[t];if(0!==r&&1!==r){if(w)for(w=0,Q+s>this.dbufSize&&d(o.DATA_ERROR),p=c[h[0]],E[p]+=s;s--;)b[Q++]=p;if(r>l)break;Q>=this.dbufSize&&d(o.DATA_ERROR),e=r-1,p=A(h,e),p=c[p],E[p]++,b[Q++]=p}else w||(w=1,s=0),s+=0===r?w:2*w,w<<=1}for((a<0||a>=Q)&&d(o.DATA_ERROR),t=0,e=0;e<256;e++)r=t+E[e],E[e]=t,t=r;for(e=0;e<Q;e++)p=255&b[e],b[E[p]]|=e<<8,E[p]++;let R=0,D=0,S=0;return Q&&(R=b[a],D=255&R,R>>=8,S=-1),this.writePos=R,this.writeCurrent=D,this.writeCount=Q,this.writeRun=S,!0}_read_bunzip(e,t){let r,n,i;if(this.writeCount<0)return 0;let a=this.dbuf,s=this.writePos,A=this.writeCurrent,c=this.writeCount,l=(this.outputsize,this.writeRun);for(;c;){for(c--,n=A,s=a[s],A=255&s,s>>=8,3===l++?(r=A,i=n,A=-1):(r=1,i=A),this.blockCRC.updateCRCRun(i,r);r--;)this.outputStream.writeByte(i),this.nextoutput++;A!=n&&(l=0)}return this.writeCount=c,this.blockCRC.getCRC()!==this.targetBlockCRC&&d(o.DATA_ERROR,"Bad block CRC (got "+this.blockCRC.getCRC().toString(16)+" expected "+this.targetBlockCRC.toString(16)+")"),this.nextoutput}}const f=function(e){if("readByte"in e)return e;const t=new s.default;return t.pos=0,t.readByte=function(){return 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this.pos++,e>=240?(e=(15&e)<<28,e+=(this.buf[this.pos+0]<<20)+(this.buf[this.pos+1]<<12)+(this.buf[this.pos+2]<<4)+(this.buf[this.pos+3]>>4),this.pos+=4):e>=224?(e=(15&e)<<24,e+=(this.buf[this.pos+0]<<16)+(this.buf[this.pos+1]<<8)+(0|this.buf[this.pos+2]),this.pos+=3):e>=192?(e=(31&e)<<16,e+=(this.buf[this.pos+0]<<8)+(0|this.buf[this.pos+1]),this.pos+=2):e>=128&&(e=(63&e)<<8,e+=this.buf[this.pos],this.pos++),e}}},3503:(e,t,r)=>{var n,i,a,s,A;n=r(3939),i=r(2151).utf8,a=r(652),s=r(2151).bin,(A=function(e,t){e.constructor==String?e=t&&"binary"===t.encoding?s.stringToBytes(e):i.stringToBytes(e):a(e)?e=Array.prototype.slice.call(e,0):Array.isArray(e)||e.constructor===Uint8Array||(e=e.toString());for(var r=n.bytesToWords(e),o=8*e.length,c=1732584193,d=-271733879,l=-1732584194,f=271733878,u=0;u<r.length;u++)r[u]=16711935&(r[u]<<8|r[u]>>>24)|4278255360&(r[u]<<24|r[u]>>>8);r[o>>>5]|=128<<o%32,r[14+(o+64>>>9<<4)]=o;var h=A._ff,g=A._gg,C=A._hh,I=A._ii;for(u=0;u<r.length;u+=16){var 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n.endian([c,d,l,f])})._ff=function(e,t,r,n,i,a,s){var A=e+(t&r|~t&n)+(i>>>0)+s;return(A<<a|A>>>32-a)+t},A._gg=function(e,t,r,n,i,a,s){var A=e+(t&n|r&~n)+(i>>>0)+s;return(A<<a|A>>>32-a)+t},A._hh=function(e,t,r,n,i,a,s){var A=e+(t^r^n)+(i>>>0)+s;return(A<<a|A>>>32-a)+t},A._ii=function(e,t,r,n,i,a,s){var A=e+(r^(t|~n))+(i>>>0)+s;return(A<<a|A>>>32-a)+t},A._blocksize=16,A._digestsize=16,e.exports=function(e,t){if(null==e)throw new Error("Illegal argument "+e);var r=n.wordsToBytes(A(e,t));return t&&t.asBytes?r:t&&t.asString?s.bytesToString(r):n.bytesToHex(r)}},3939:e=>{var t,r;t="ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+/",r={rotl:function(e,t){return e<<t|e>>>32-t},rotr:function(e,t){return e<<32-t|e>>>t},endian:function(e){if(e.constructor==Number)return 16711935&r.rotl(e,8)|4278255360&r.rotl(e,24);for(var t=0;t<e.length;t++)e[t]=r.endian(e[t]);return e},randomBytes:function(e){for(var t=[];e>0;e--)t.push(Math.floor(256*Math.random()));return t},bytesToWords:function(e){for(var t=[],r=0,n=0;r<e.length;r++,n+=8)t[n>>>5]|=e[r]<<24-n%32;return t},wordsToBytes:function(e){for(var t=[],r=0;r<32*e.length;r+=8)t.push(e[r>>>5]>>>24-r%32&255);return t},bytesToHex:function(e){for(var t=[],r=0;r<e.length;r++)t.push((e[r]>>>4).toString(16)),t.push((15&e[r]).toString(16));return t.join("")},hexToBytes:function(e){for(var t=[],r=0;r<e.length;r+=2)t.push(parseInt(e.substr(r,2),16));return t},bytesToBase64:function(e){for(var r=[],n=0;n<e.length;n+=3)for(var i=e[n]<<16|e[n+1]<<8|e[n+2],a=0;a<4;a++)8*n+6*a<=8*e.length?r.push(t.charAt(i>>>6*(3-a)&63)):r.push("=");return r.join("")},base64ToBytes:function(e){e=e.replace(/[^A-Z0-9+\/]/gi,"");for(var r=[],n=0,i=0;n<e.length;i=++n%4)0!=i&&r.push((t.indexOf(e.charAt(n-1))&Math.pow(2,-2*i+8)-1)<<2*i|t.indexOf(e.charAt(n))>>>6-2*i);return r}},e.exports=r},4056:function(e,t,r){"use strict";var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(4141)),a=r(6761),s=r(6272);class A extends i.default{constructor(e,t){if(super(e,t),this.codes={},this.codeBook={},this.sortedCodes=[],this.sortedValuesByBitCode=[],this.sortedBitCodes=[],this.sortedBitLengthsByBitCode=[],this.bitCodeToValue=[],!["byte","int"].includes(this.dataType))throw new TypeError(`${this.dataType} decoding not yet implemented by HUFFMAN_INT codec`);this.buildCodeBook(),this.buildCodes(),this.buildCaches(),0===this.sortedCodes[0].bitLength&&(this._decode=this._decodeZeroLengthCode)}buildCodeBook(){let e=new Array(this.parameters.numCodes);for(let t=0;t<this.parameters.numCodes;t++)e[t]={symbol:this.parameters.symbols[t],bitLength:this.parameters.bitLengths[t]};e=e.sort((e,t)=>e.bitLength-t.bitLength||e.symbol-t.symbol),this.codeBook={},e.forEach(e=>{this.codeBook[e.bitLength]||(this.codeBook[e.bitLength]=[]),this.codeBook[e.bitLength].push(e.symbol)})}buildCodes(){this.codes={};let e=0,t=-1;Object.entries(this.codeBook).forEach(([r,n])=>{const i=Number.parseInt(r,10);n.forEach(r=>{const n={bitLength:i,value:r,bitCode:0};t+=1;const a=i-e;if(t<<=a,n.bitCode=t,e+=a,function(e){let t=e-(e>>1)&1431655765;return t=(858993459&t)+(t>>2&858993459),16843009*(t+(t>>4)&252645135)>>24}(t)>i)throw new s.CramMalformedError("Symbol out of 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s)A.push(...e);A=A.sort((e,t)=>e.toString().localeCompare(t.toString())).filter((e,t,r)=>!t||e.toString()!==r[t-1].toString());const c=[],d=[];for(const e of A){let n=this.cram.featureCache.get(e.toString());n||(n=this.getRecordsInSlice(e,()=>!0),this.cram.featureCache.set(e.toString(),n)),c.push(n);const i=n.then(e=>{const n=[];for(const i of e){if(void 0===i.readName)throw new Error("readName undefined");r[i.readName]&&!t[i.uniqueId]&&n.push(i)}return n});d.push(i)}const l=await Promise.all(d);if(l.length){const e=l.reduce((e,t)=>e.concat(t));o=o.concat(e)}}return o}getRecordsInSlice({containerStart:e,sliceStart:t,sliceBytes:r},n){return this.cram.getContainerAtPosition(e).getSlice(t,r).getRecords(n)}hasDataForReferenceSequence(e){return this.index.hasDataForReferenceSequence(e)}}},8485:(e,t)=>{"use strict";function r(e){return("object"==typeof e&&null!==e&&"message"in 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this.fetch(this.url,{...this.baseOverrides,...a,headers:{...n,...a.headers,...this.baseOverrides.headers},method:"GET",redirect:"follow",mode:"cors",signal:i});if(!s.ok)throw new Error(`HTTP ${s.status} fetching ${this.url}`);if(200===s.status&&0===t||206===s.status){const t=await s.arrayBuffer(),r=s.headers.get("content-range"),n=/\/(\d+)$/.exec(r||"");return n?.[1]&&(this._stat={size:parseInt(n[1],10)}),new Uint8Array(t.slice(0,e))}throw 200===s.status?new Error(`${this.url} fetch returned status 200, expected 206`):new Error(`HTTP ${s.status} fetching ${this.url}`)}async readFile(e={}){let t,r;"string"==typeof e?(t=e,r={}):(t=e.encoding,r=e,delete r.encoding);const{headers:n={},signal:i,overrides:a={}}=r,s=await this.fetch(this.url,{headers:n,method:"GET",redirect:"follow",mode:"cors",signal:i,...this.baseOverrides,...a});if(200!==s.status)throw new Error(`HTTP ${s.status} fetching ${this.url}`);if("utf8"===t)return s.text();if(t)throw new Error(`unsupported encoding: ${t}`);return 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t[0][e[0]>>6&3]="C",t[0][e[0]>>4&3]="G",t[0][e[0]>>2&3]="T",t[0][3&e[0]]="N",t[1][e[1]>>6&3]="A",t[1][e[1]>>4&3]="G",t[1][e[1]>>2&3]="T",t[1][3&e[1]]="N",t[2][e[2]>>6&3]="A",t[2][e[2]>>4&3]="C",t[2][e[2]>>2&3]="T",t[2][3&e[2]]="N",t[3][e[3]>>6&3]="A",t[3][e[3]>>4&3]="C",t[3][e[3]>>2&3]="G",t[3][3&e[3]]="N",t[4][e[4]>>6&3]="A",t[4][e[4]>>4&3]="C",t[4][e[4]>>2&3]="G",t[4][3&e[4]]="T",t}(e.preservation.SM),this.dataSeriesEncoding=e.dataSeriesEncoding,this.tagEncoding=e.tagEncoding}getCodecForTag(e){const t=this.tagCodecCache[e];if(t)return t;{const t=this.tagEncoding[e];if(!t)throw new Error("Error, no tag encoding");const r=(0,i.instantiateCodec)(t,"byteArray");return this.tagCodecCache[e]=r,r}}getTagNames(e){return this.tagIdsDictionary[e]}getCodecForDataSeries(e){let t=this.dataSeriesCodecCache[e];if(void 0===t){const r=this.dataSeriesEncoding[e];if(r){const s=a[e];if(!s)throw new n.CramMalformedError(`data series name ${e} not defined in file compression header`);t=(0,i.instantiateCodec)(r,s),this.dataSeriesCodecCache[e]=t}}return t}toJSON(){const e={};return Object.keys(this).forEach(t=>{t.endsWith("Cache")||(e[t]=this[t])}),e}}},8751:function(e,t,r){"use strict";var n,i=this&&this.__createBinding||(Object.create?function(e,t,r,n){void 0===n&&(n=r);var i=Object.getOwnPropertyDescriptor(t,r);i&&!("get"in i?!t.__esModule:i.writable||i.configurable)||(i={enumerable:!0,get:function(){return t[r]}}),Object.defineProperty(e,n,i)}:function(e,t,r,n){void 0===n&&(n=r),e[n]=t[r]}),a=this&&this.__setModuleDefault||(Object.create?function(e,t){Object.defineProperty(e,"default",{enumerable:!0,value:t})}:function(e,t){e.default=t}),s=this&&this.__importStar||(n=function(e){return n=Object.getOwnPropertyNames||function(e){var t=[];for(var r in e)Object.prototype.hasOwnProperty.call(e,r)&&(t[t.length]=r);return t},n(e)},function(e){if(e&&e.__esModule)return e;var t={};if(null!=e)for(var r=n(e),s=0;s<r.length;s++)"default"!==r[s]&&i(t,e,r[s]);return a(t,e),t}),A=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const o=A(r(86)),c=A(r(7392)),d=r(6272),l=s(r(4562)),f=r(6727),u=A(r(2670)),h=r(5011),g=r(2549),C=r(870),I=r(2169),_=A(r(2845)),B=r(7580),m=r(252);class E{constructor(e){if(this.file=(0,f.open)(e.url,e.path,e.filehandle),this.validateChecksums=!0,this.fetchReferenceSequenceCallback=e.seqFetch,this.options={checkSequenceMD5:e.checkSequenceMD5,cacheSize:e.cacheSize??2e4},this.featureCache=new c.default({maxSize:this.options.cacheSize}),function(){const e=new Uint32Array([287454020]),t=new Uint8Array(e.buffer);return 68===t[0]?0:17===t[0]?1:2}()>0)throw new Error("Detected big-endian machine, may be unable to run")}read(e,t){return this.file.read(e,t)}async getDefinition(){const{maxLength:e,parser:t}=(0,B.cramFileDefinition)(),r=t(await this.file.read(e,0)).value;if("CRAM"!==r.magic)throw new Error("Not a CRAM file, does not match magic string");if(2!==r.majorVersion&&3!==r.majorVersion)throw new d.CramUnimplementedError(`CRAM version ${r.majorVersion} not supported`);return r}async getSamHeader(){const e=await this.getContainerById(0);if(!e)throw new d.CramMalformedError("file contains no containers");const t=(await e.getFirstBlock()).content,r=new DataView(t.buffer).getInt32(0,!0),n=new TextDecoder("utf8").decode(t.subarray(4,4+r));return this.header=n,(0,h.parseHeaderText)(n)}async getHeaderText(){return await this.getSamHeader(),this.header}async getContainerById(e){if(!this._sectionParsers){const{majorVersion:e}=await this.getDefinition();this._sectionParsers=(0,B.getSectionParsers)(e)}let t,r=this._sectionParsers.cramFileDefinition.maxLength;for(let n=0;n<=e;n++){t=this.getContainerAtPosition(r);const e=await t.getHeader();if(0===n){r=e._endPosition;for(let t=0;t<e.numBlocks;t++)r=(await this.readBlock(r))._endPosition}else r+=e._size+e.length}return t}async checkCrc32(e,t,r,n){const i=await this.file.read(t,e),a=(0,o.default)(i)>>>0;if(a!==r)throw new d.CramMalformedError(`crc mismatch in ${n}: recorded CRC32 = ${r}, but calculated CRC32 = ${a}`)}async containerCount(){if(!this._sectionParsers){const{majorVersion:e}=await this.getDefinition();this._sectionParsers=(0,B.getSectionParsers)(e)}let e=0,t=this._sectionParsers.cramFileDefinition.maxLength;try{for(;;){const r=await this.getContainerAtPosition(t).getHeader();if(0===e){t=r._endPosition;for(let e=0;e<r.numBlocks;e++)t=(await this.readBlock(t))._endPosition}else t+=r._size+r.length;e+=1}}catch(t){e--}return e}getContainerAtPosition(e){return new _.default(this,e)}async readBlockHeader(e){if(!this._sectionParsers){const{majorVersion:e}=await this.getDefinition();this._sectionParsers=(0,B.getSectionParsers)(e)}const{cramBlockHeader:t}=this._sectionParsers,r=await this.file.read(t.maxLength,e);return(0,g.parseItem)(r,t.parser,0,e)}async _parseSection(e,t,r=e.maxLength,n){const i=n??await 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"},8930:function(e,t,r){"use strict";var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(4141)),a=r(6272),s=r(2549),A=r(6761);class o extends i.default{constructor(e,t){if(super(e,t),"int"!==this.dataType&&"byte"!==this.dataType)throw new a.CramUnimplementedError(`${this.dataType} decoding not yet implemented by EXTERNAL codec`)}decode(e,t,r,n){const{blockContentId:i}=this.parameters,a=r[i];if(!a)return;const o=n.externalBlocks.getCursor(i);if("int"===this.dataType){const[e,t]=(0,s.parseItf8)(a.content,o.bytePosition);return o.bytePosition+=t,e}if(o.bytePosition>=a.content.length)throw new A.CramBufferOverrunError("attempted to read beyond end of block. this file seems truncated.");return a.content[o.bytePosition++]}}t.default=o},9301:(e,t,r)=>{"use strict";Object.defineProperty(t,"__esModule",{value:!0});const n=r(6272),i=r(7151);function a(e,t,r,n){return r*(e>>n)+(e&(1<<n)-1)-t}t.default={FC:class{constructor(){this.F=void 0,this.C=void 0}},AriDecoder:class{constructor(){this.fcF=new Array(256),this.fcC=new Array(256),this.R=null}},DecodingSymbol:class{constructor(){this.start=void 0,this.freq=void 0}},symbolInit:function(e,t,r){if(!(t<=65536))throw new n.CramMalformedError("assertion failed: start <= 1<<16");if(!(r<=65536-t))throw new n.CramMalformedError("assertion failed: freq <= 1<<16");e.start=t,e.freq=r},advanceStep:a,advanceSymbolStep:function(e,t,r){return a(e,t.start,t.freq,r)},get:function(e,t){return e&(1<<t)-1},advanceSymbol:function(e,t,r,n){return function(e,t,r,n,a){if((e=n*(e>>a)+(e&(1<<a)-1)-r)<i.RANS_BYTE_L)do{e=e<<8|255&t.get()}while(e<i.RANS_BYTE_L);return e}(e,t,r.start,r.freq,n)},renormalize:function(e,t){if(e<i.RANS_BYTE_L)do{e=e<<8|255&t.get()}while(e<i.RANS_BYTE_L);return e}}},9313:function(e,t,r){"use strict";var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.decode=function(e){return d(new i.default(e),0)};const i=n(r(3088));function a(e,t){return e&(1<<t)-1}function s(e,t){let r=0;for(;t>=e[r+1];)r++;return r}function A(e,t){const r=1<<t,n=new Array(r);let i=0;for(let t=0;t<r;t++){for(;t>=e[i+1];)i++;n[t]=i}return n}function o(e,t,r,n){return r*(e>>n)+(e&(1<<n)-1)-t}function c(e,t){return t<32768&&(t=(t<<16)+e.ReadUint16()),t}function d(e,t){const r=e.ReadByte(),n=1&r,h=8&r,g=32&r,C=64&r,I=128&r,_=4&r?32:4;if(16&r||(t=e.ReadUint7()),h)return function(e,t){const r=e.ReadByte(),n=new Array(r),i=new Array(r);for(var a=0;a<r;a++)n[a]=e.ReadUint7();const s=new Array(r);for(a=0;a<r;a++)i[a]=Math.floor(t/r)+(t%r>a),s[a]=d(e,i[a]);const A=new Uint8Array(t);for(a=0;a<r;a++)for(let e=0;e<i[a];e++)A[e*r+a]=s[a][e];return A}(e,t);if(I)var B=t,[m,E,t]=function(e){const t=e.ReadByte(),r=new Array(t);for(let n=0;n<t;n++)r[n]=e.ReadByte();return[r,t,e.ReadUint7()]}(e);if(C)var p=t,[w,Q,t]=function(e,t){const r=e.ReadUint7(),n=e.ReadUint7();if(1&r)var a=e.ReadData((r-1)/2);else{const n=e.ReadUint7();a=e.ReadData(n),a=f(new i.default(a),r/2,t)}a=new i.default(a);const s=new Array(256);let A=a.ReadByte();0==A&&(A=256);for(let e=0;e<A;e++)s[a.ReadByte()]=1;return[s,a,n]}(e,_);if(g)var y=e.ReadData(t);else y=0==n?f(e,t,_):function(e,t,r){const n=(h=e.ReadByte())>>4;var d=e;if(1&h){const t=e.ReadUint7(),r=e.ReadUint7();var h=new i.default(e.ReadData(r));d=new i.default(f(h,t,4))}const g=new Array(256),C=new Array(256);!function(e,t,r,n){for(var i=0;i<256;i++){t[i]=new Array(256),r[i]=new Array(256);for(var a=0;a<256;a++)t[i][a]=0}const s=l(e);for(i=0;i<256;i++){if(!s[i])continue;let A=0;for(a=0;a<256;a++)s[a]&&(A>0?A--:(t[i][a]=e.ReadUint7(),0==t[i][a]&&(A=e.ReadByte())));for(u(t[i],n),r[i][0]=0,a=0;a<256;a++)r[i][a+1]=r[i][a]+t[i][a]}}(d,g,C,n);const I=new Array(256);for(var _=0;_<256;_++)I[_]=A(C[_],n);const B=new Array(r),m=new Array(r);for(var E=0;E<r;E++)B[E]=e.ReadUint32(),m[E]=0;const p=new Uint8Array(t),w=Math.floor(t/r);for(_=0;_<w;_++)for(E=0;E<r;E++){var Q=a(B[E],n),y=I[m[E]][Q];p[_+E*w]=y,B[E]=o(B[E],C[m[E]][y],g[m[E]][y],n),B[E]=c(e,B[E]),m[E]=y}for(_*=r;_<t;)Q=a(B[r-1],n),y=s(C[m[r-1]],Q),p[_++]=y,B[r-1]=o(B[r-1],C[m[r-1]][y],g[m[r-1]][y],n),B[r-1]=c(e,B[r-1]),m[r-1]=y;return p}(e,t,_);return C&&(y=function(e,t,r,n){new i.default(e);const a=new Uint8Array(n);let s=0;for(let i=0;s<n;i++){const n=e[i];if(t[n]){const e=r.ReadUint7();for(let t=0;t<=e;t++)a[s++]=n}else a[s++]=n}return a}(y,w,Q,p)),I&&(y=function(e,t,r,n){const i=new Uint8Array(n);let a=0;if(r<=1)for(var s=0;s<n;s++)i[s]=t[0];else if(r<=2)for(s=0;s<n;s++){if(s%8==0)var A=e[a++];i[s]=t[1&A],A>>=1}else if(r<=4)for(s=0;s<n;s++)s%4==0&&(A=e[a++]),i[s]=t[3&A],A>>=2;else if(r<=16)for(s=0;s<n;s++)s%2==0&&(A=e[a++]),i[s]=t[15&A],A>>=4;return i}(y,m,E,B)),y}function l(e){const t=new Array(256);for(let e=0;e<256;e++)t[e]=0;let r=0,n=e.ReadByte(),i=n;do{t[n]=1,r>0?(r--,n++):(n=e.ReadByte(),n==i+1&&(r=e.ReadByte())),i=n}while(0!=n);return t}function f(e,t,r){const n=new Array(256),i=new Array(256);!function(e,t,r){for(var n=0;n<256;n++)t[n]=0;const i=l(e);for(n=0;n<256;n++)i[n]>0&&(t[n]=e.ReadUint7());for(u(t,12),r[0]=0,n=0;n<=255;n++)r[n+1]=r[n]+t[n]}(e,n,i);const s=A(i,12),d=new Array(r);for(var f=0;f<r;f++)d[f]=e.ReadUint32();const h=new Uint8Array(t);for(f=0;f<t;f++){const t=f&r-1,A=s[a(d[t],12)];h[f]=A,d[t]=o(d[t],i[A],n[A],12),d[t]=c(e,d[t])}return h}function u(e,t){let r=0;for(var n=0;n<256;n++)r+=e[n];if(0==r||r==1<<t)return;let i=0;for(;r<1<<t;)r*=2,i++;for(n=0;n<256;n++)e[n]<<=i}},9368:(e,t)=>{"use strict";Object.defineProperty(t,"__esModule",{value:!0}),t.default={2:"need dictionary",1:"stream end",0:"","-1":"file error","-2":"stream error","-3":"data error","-4":"insufficient memory","-5":"buffer error","-6":"incompatible 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r=new Uint8Array(t);let n=e.ReadByte();0==n&&(n=256);const i=new Array(n);for(var A=0;A<n;A++)i[A]=new s.default(n);const o=new a.default(e);o.RangeStartDecode(e);let c=0;for(A=0;A<t;A++)r[A]=i[c].ModelDecode(e,o),c=r[A];return r}decodeExt(e,t){return(0,i.decode)(e.buf.slice(e.pos))}decodeRLE0(e,t){const r=new Uint8Array(t);let n=e.ReadByte();0==n&&(n=256);const i=new s.default(n),A=new Array(258);for(var o=0;o<=257;o++)A[o]=new s.default(4);const c=new a.default(e);for(c.RangeStartDecode(e),o=0;o<t;){r[o]=i.ModelDecode(e,c);let t=A[r[o]].ModelDecode(e,c),n=t,a=256;for(;3==t;)t=A[a].ModelDecode(e,c),a=257,n+=t;for(let e=1;e<=n;e++)r[o+e]=r[o];o+=n+1}return r}decodeRLE1(e,t){const r=new Uint8Array(t);let n=e.ReadByte();0==n&&(n=256);const i=new Array(n);for(var A=0;A<n;A++)i[A]=new s.default(n);const o=new Array(258);for(A=0;A<=257;A++)o[A]=new s.default(4);const c=new a.default(e);c.RangeStartDecode(e);let d=0;for(A=0;A<t;){r[A]=i[d].ModelDecode(e,c),d=r[A];let t=o[r[A]].ModelDecode(e,c),n=t,a=256;for(;3==t;)t=o[a].ModelDecode(e,c),a=257,n+=t;for(let e=1;e<=n;e++)r[A+e]=r[A];A+=n+1}return r}decodePackMeta(e){this.nsym=e.ReadByte();const t=new Array(this.nsym);for(let r=0;r<this.nsym;r++)t[r]=e.ReadByte();return[t,e.ReadUint7()]}decodePack(e,t,r){const n=new Uint8Array(r);if(this.nsym<=1)for(var i=0;i<r;i++)n[i]=t[0];else if(this.nsym<=2){i=0;for(var a=0;i<r;i++){if(i%8==0)var s=e[a++];n[i]=t[1&s],s>>=1}}else if(this.nsym<=4)for(i=0,a=0;i<r;i++)i%4==0&&(s=e[a++]),n[i]=t[3&s],s>>=2;else{if(!(this.nsym<=16))return e;for(i=0,a=0;i<r;i++)i%2==0&&(s=e[a++]),n[i]=t[15&s],s>>=4}return n}packMeta(e){const t=new A.default("",0,1024),r=new Array(256);for(var n=0;n<e.length;n++)r[e[n]]=1;var i=0;for(n=0;n<256;n++)r[n]&&(r[n]=++i);for(t.WriteByte(i),n=0;n<256;n++)r[n]&&(t.WriteByte(n),r[n]--);return[t,r,i]}decodeStripe(e,t){const r=e.ReadByte(),n=new Array(r),i=new Array(r);for(var a=0;a<r;a++)n[a]=e.ReadUint7();const s=new Array(r);for(a=0;a<r;a++)i[a]=Math.floor(t/r)+(t%r>a),s[a]=this.decodeStream(e,i[a]);const A=new Uint8Array(t);for(a=0;a<r;a++)for(let e=0;e<i[a];e++)A[e*r+a]=s[a][e];return A}decodeCat(e,t){const r=new Uint8Array(t);for(let n=0;n<t;n++)r[n]=e.ReadByte();return r}}},9685:(e,t,r)=>{"use strict";Object.defineProperty(t,"__esModule",{value:!0}),t.default=function(e,t,r,o,c,d,l,f,u){let h=t("BF");const g=t("CF");if(!(0,a.isMappedSliceHeader)(o.parsedContent))throw new Error("slice header not mapped");const C=f>1&&-2===o.parsedContent.refSeqId?t("RI"):o.parsedContent.refSeqId,I=t("RL");let _=t("AP");r.APdelta&&(_+=l.lastAlignmentStart),l.lastAlignmentStart=_;const B=t("RG");let m,E,p,w;if(r.readNamesIncluded&&(m=s(t("RN"))),i.CramFlagsDecoder.isDetached(g)){const e=t("MF");let n;r.readNamesIncluded||(n=s(t("RN")),m=n);const a=t("NS"),A=t("NP");(e||a>-1)&&(E={mateFlags:e,mateSequenceId:a,mateAlignmentStart:A,mateReadName:n}),p=t("TS"),i.MateFlagsDecoder.isUnmapped(e)&&(h=i.BamFlagsDecoder.setMateUnmapped(h)),i.MateFlagsDecoder.isOnNegativeStrand(e)&&(h=i.BamFlagsDecoder.setMateReverseComplemented(h))}else i.CramFlagsDecoder.isWithMateDownstream(g)&&(w=t("NF")+u+1);const Q=t("TL");if(Q<0)throw new n.CramMalformedError("invalid TL index");const y={},b=r.getTagNames(Q),R=b.length;for(let t=0;t<R;t++){const n=b[t],i=n.slice(0,2),a=n.slice(2,3),s=r.getCodecForTag(n).decode(e,c,d,l);y[i]=void 0===s?void 0:"number"==typeof s?s:A(a,s)}let D,S,v,k,F;if(i.BamFlagsDecoder.isSegmentUnmapped(h))if(i.CramFlagsDecoder.isDecodeSequenceAsStar(g))F=null,k=null;else{const e=new Array(I);for(let r=0;r<e.length;r++)e[r]=t("BA");if(F=String.fromCharCode(...e),i.CramFlagsDecoder.isPreservingQualityScores(g)){k=new Array(I);for(let r=0;r<e.length;r++)k[r]=t("QS")}}else{const e=t("FN");if(e&&(D=function(e,t,r,i,a){let s=0,A=e-1;const o=new Array(t);function c([e,t]){const n=r(t);if("character"===e)return String.fromCharCode(n);if("string"===e){let e="";for(let t=0;t<n.byteLength;t++)e+=String.fromCharCode(n[t]);return e}return"numArray"===e?Array.from(n):n}for(let e=0;e<t;e++){const t=String.fromCharCode(r("FC")),i=r("FP"),d={B:["character","BA"],S:["string",a>1?"SC":"IN"],X:["number","BS"],D:["number","DL"],I:["string","IN"],i:["character","BA"],b:["string","BB"],q:["numArray","QQ"],Q:["number","QS"],H:["number","HC"],P:["number","PD"],N:["number","RS"]}[t];if(!d)throw new n.CramMalformedError(`invalid read feature code "${t}"`);let l=c(d);const f={B:["number","QS"]}[t];f&&(l=[l,c(f)]),s+=i;const u=s;A+=i;const h=A;"D"===t||"N"===t?A+=l:"I"===t||"S"===t?A-=l.length:"i"===t&&(A-=1),o[e]={code:t,pos:u,refPos:h,data:l}}return o}(_,e,t,0,f)),S=I,D)for(const{code:e,data:t}of D)"D"===e||"N"===e?S+=t:"I"===e||"S"===e?S-=t.length:"i"===e&&(S-=1);if(Number.isNaN(S)&&(console.warn(`${m||`${C}:${_}`} record has invalid read features`),S=I),v=t("MQ"),i.CramFlagsDecoder.isPreservingQualityScores(g)){k=new Array(I);for(let e=0;e<k.length;e++)k[e]=t("QS")}}return{readLength:I,sequenceId:C,cramFlags:g,flags:h,alignmentStart:_,readGroupId:B,readName:m,mateToUse:E,templateSize:p,mateRecordNumber:w,readFeatures:D,lengthOnRef:S,mappingQuality:v,qualityScores:k,readBases:F,tags:y}};const n=r(6272),i=r(7480),a=r(7580);function s(e){let t="";for(let r=0;r<e.length&&0!==e[r];r++)t+=String.fromCharCode(e[r]);return t}function A(e,t){if("Z"===e)return s(t);if("A"===e)return String.fromCharCode(t[0]);if("I"===e)return new Uint32Array(t.buffer)[0];if("i"===e)return new Int32Array(t.buffer)[0];if("s"===e)return new Int16Array(t.buffer)[0];if("S"===e)return new Uint16Array(t.buffer)[0];if("c"===e)return new Int8Array(t.buffer)[0];if("C"===e)return t[0];if("f"===e)return new Float32Array(t.buffer)[0];if("H"===e)return Number.parseInt(s(t).replace(/^0x/,""),16);if("B"===e)return function(e){const t=String.fromCharCode(e[0]),r=new DataView(e.buffer).getUint32(1,!0),n=new Array(r);if(e=e.slice(5),"c"===t){const t=new Int8Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e]}else if("C"===t){const t=new Uint8Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e]}else if("s"===t){const t=new Int16Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e]}else if("S"===t){const t=new Uint16Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e]}else if("i"===t){const t=new Int32Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e]}else if("I"===t){const t=new Uint32Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e]}else{if("f"!==t)throw new Error(`unknown type: ${t}`);{const t=new Float32Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e]}}return n}(t);throw new n.CramMalformedError(`Unrecognized tag type ${e}`)}}},t={},r=function r(n){var i=t[n];if(void 0!==i)return i.exports;var a=t[n]={exports:{}};return e[n].call(a.exports,a,a.exports,r),a.exports}(5159);window.gmodCRAM=r})();