@glycanage/web-components 1.57.0 → 1.59.0
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/dist/arthritis.wc.js +2 -2
- package/dist/helpers.js +1 -1
- package/package.json +1 -1
package/dist/arthritis.wc.js
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import{c as Ge,S as Re,i as Me,f as C,s as Se,a as Pe,e as f,b as x,d as
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During the entire course of pregnancy and the postpartum period, a consistent reduction in galactosylation and sialylation was observed among the RA patients.</p> <a href="https://pubmed.ncbi.nlm.nih.gov/28793911/" class="svelte-1285zfm">IgG Fc galactosylation predicts response to methotrexate in early rheumatoid arthritis</a> <p class="svelte-1285zfm">In a study of Swedish patients with early rheumatoid arthritis (RA), 73% of whom were women with an average age of 53, compared to a control group comprising 72% women with an average age of 54, an increase in G0 was observed, while G1 and G2 were decreased. No changes were noted in B and S.</p> <a href="https://pubmed.ncbi.nlm.nih.gov/29572115/" class="svelte-1285zfm">Low galactosylation of IgG associates with higher risk for future diagnosis of rheumatoid arthritis during 10 years of follow-up</a> <p class="svelte-1285zfm">In an extensive study which encompassed two Finnish cohorts totaling 14,749 individuals, 179 subjects who developed rheumatoid arthritis (RA) were monitored over a 10-year period alongside 358 matched controls, 59% of whom were female. The analysis uncovered a reduction in G0 and an elevation in G1, with a nominally significant decrease observed in G2 and S; B was not assessed. Notably, the research identified a specific G0 glycan peak as a crucial pre-existing risk factor for the onset of RA.</p>',O(l,"transform","translate(-50%)"),O(p,"color",r[3]?"#F2590D":"#12A195"),a(t,"class","summaryHeader svelte-1285zfm"),a(u,"class","svelte-1285zfm"),a(g,"class","svelte-1285zfm"),a(L,"class","svelte-1285zfm"),a(N,"class","svelte-1285zfm"),a(k,"class","svelte-1285zfm"),a(v,"class","svelte-1285zfm"),a(X,"class","svelte-1285zfm"),a(J,"class","svelte-1285zfm"),a(Q,"class","svelte-1285zfm"),a(F,"class","svelte-1285zfm"),a(te,"class","svelte-1285zfm"),a(w,"class","summaryBody svelte-1285zfm"),a(e,"class","summaryMain svelte-1285zfm")},m($,Z){G($,e,Z),i(e,t),i(t,l),W.m(l,null),i(t,s),i(t,h),i(h,p),V.m(p,null),i(h,m),i(h,c),i(e,n),i(e,u),i(e,E),i(e,w),i(w,g),i(g,M),i(w,y),i(w,v),i(v,L),i(L,T),i(v,P),i(v,N),i(N,oe),i(v,ve),i(v,k),i(k,de),i(w,ge),i(w,X),i(X,ce),i(w,we),i(w,F),i(F,J),i(J,fe),i(F,Le),i(F,Q),i(Q,pe),i(w,ze),i(w,te),i(te,ue),i(w,ye),i(w,he)},p($,Z){ie!==(ie=Te($))&&(W.d(1),W=ie($),W&&(W.c(),W.m(l,null))),se===(se=xe($))&&V?V.p($,Z):(V.d(1),V=se($),V&&(V.c(),V.m(p,null))),Z&8&&O(p,"color",$[3]?"#F2590D":"#12A195"),Z&1&&d!==(d=z($[0],"OVERLAP_TEXT")+"")&&b(c,d),Z&1&&A!==(A=z($[0],"SYMPTOMS")+"")&&b(M,A),Z&1&&o!==(o=z($[0],"SYMPTOM_TWENTY")+"")&&b(T,o),Z&1&&H!==(H=z($[0],"SYMPTOM_TWENTYONE")+"")&&b(oe,H),Z&1&&U!==(U=z($[0],"SYMPTOM_TWENTYTWO")+"")&&b(de,U),Z&1&&j!==(j=z($[0],"POSSIBLE_FOLLOW_UP")+"")&&b(ce,j),Z&1&&K!==(K=z($[0],"POSSIBLE_FOLLOW_UP_TWENTYTWO")+"")&&b(fe,K),Z&1&&ee!==(ee=z($[0],"POSSIBLE_FOLLOW_UP_TWENTYTHREE")+"")&&b(pe,ee),Z&1&&le!==(le=z($[0],"RELATED_RESEARCH_PAPERS")+"")&&b(ue,le)},i:q,o:q,d($){$&&R(e),W.d(),V.d()}}}function We(r){let e,t,l,s,h,p,m;function d(g,A){return g[3]||g[4]?ke:He}let c=d(r),n=c(r);function u(g,A){return g[3]?je:g[4]?Xe:Ue}let E=u(r),w=E(r);return{c(){e=f("div"),t=f("div"),l=f("b"),s=_(r[9]),h=_("/4"),p=x(),n.c(),m=_(`
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TK klatki piersiowej, TK jamy brzusznej)",POSSIBLE_FOLLOW_UP_FOURTEEN:"Badania krwi: pe\u0142na morfologia krwi, czynno\u015B\u0107 nerek i w\u0105troby, st\u0119\u017Cenie glukozy i insuliny na czczo, HbA1c, HOMA-IR",POSSIBLE_FOLLOW_UP_FIFTEEN:"Badania profilu lipidowego krwi: podstawowe i rozszerzone (np. oxLDL, Lp(a), ApoB))",POSSIBLE_FOLLOW_UP_SIXTEEN:"Inne badania krwi hsCRP, homocysteina, czynno\u015B\u0107 nerek i w\u0105troby, HbA1c",POSSIBLE_FOLLOW_UP_SEVENTEEN:"Badania krwi: pe\u0142na morfologia krwi",POSSIBLE_FOLLOW_UP_EIGHTEEN:"Spirometria",POSSIBLE_FOLLOW_UP_NINETEEN:"EKG, RTG klatki piersiowej",POSSIBLE_FOLLOW_UP_TWENTY:"Badania krwi (w tym FSH, estradiol, progesteron, testosteron, AMH)",POSSIBLE_FOLLOW_UP_TWENTYONE:"Skierowanie do specjalisty/ginekologa zajmuj\u0105cego si\u0119 (peri)menopauz\u0105",POSSIBLE_FOLLOW_UP_TWENTYTWO:"Badania krwi: pe\u0142na morfologia krwi, czynnik reumatoidalny, przeciwcia\u0142a anty-CCP, CRP",POSSIBLE_FOLLOW_UP_TWENTYTHREE:"Obrazowanie staw\xF3w (zdj\u0119cia rentgenowskie, rezonans magnetyczny)",RISK_FACTORS:"Czynniki ryzyka",RISK_FACTOR_ONE:"Historia chor\xF3b (np. zesp\xF3\u0142 kardiometaboliczny, choroby autoimmunologiczne)",RISK_FACTOR_TWO:"Historia przyjmowania lek\xF3w (np. statyn, lek\xF3w przeciwzakrzepowych)",RISK_FACTOR_THREE:"Palenie tytoniu",RELATED_RESEARCH_PAPERS:"Publikacje naukowe"};function Te(e){if(e===11||e===12||e===13)return"th";switch(e.toString().split("").pop()){case"1":return"st";case"2":return"nd";case"3":return"rd";default:return"th"}}function ye(e,t="english"){const n={english:G,polish:x};if(e<32)return n[t].LOWER_THAN_AVERAGE;if(e>=32&&e<=68)return n[t].AROUND_AVERAGE;if(e>68)return n[t].HIGHER_THAN_AVERAGE}function we(e="english",t){return{english:G,polish:x}[e][t]}export{C as A,Te as B,Pe as S,q as a,te as b,fe as c,ne as d,y as e,b as f,F as g,de as h,Le as i,H as j,T as k,_e as l,ye as m,we as n,ce as o,w as p,ae as q,Y as r,X as s,he as t,W as u,ie as v,f as w,ee as x,pe as y,j as z};
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(e.g., self-resolving chest pain, breathlessness)",SYMPTOM_FIVE:"Signs of peripheral artery disease (e.g., leg pain during activity)",SYMPTOM_SIX:"Self-limiting chest pain \xB1 radiation into jaw/left arm/back",SYMPTOM_SEVEN:"Breathlessness",SYMPTOM_EIGHT:"Other (syncope, palpitations, leg edema, orthopnea, etc.)",SYMPTOM_NINE:"Abdominal pain and cramping/left arm/back",SYMPTOM_TEN:"Recurring diarrhea (\xB1 blood)",SYMPTOM_ELEVEN:"Weight loss",SYMPTOM_TWELVE:"Systemic (e.g., fatigue, weight loss, mouth ulcers, butterfly skin rash)",SYMPTOM_THIRTEEN:"Organ-specific (chest pain, difficulty breathing, leg swelling, anaemia, etc.)",SYMPTOM_FOURTEEN:"Joint pain and swelling",SYMPTOM_FIFTEEN:"Fatigue",SYMPTOM_SIXTEEN:"Increased thirst and frequent urination",SYMPTOM_SEVENTEEN:"Slow wound healing, blurred vision, frequent thrush",SYMPTOM_EIGHTEEN:"Difficulty breathing",SYMPTOM_NINETEEN:"Chronic cough (\xB1 productive)",SYMPTOM_TWENTY:"Irregular menstrual cycle",SYMPTOM_TWENTYONE:"Vasomotor 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count, renal and liver function, CRP",POSSIBLE_FOLLOW_UP_NINE:"Stool tests: faecal immunochemical test (FIT), faecal calprotectin",POSSIBLE_FOLLOW_UP_TEN:"Referral for CT colonoscopy",POSSIBLE_FOLLOW_UP_ELEVEN:"Blood tests: full blood count, renal and liver function, CRP, ESR, autoantibodies (e.g., ANA, anti-dsDNA)",POSSIBLE_FOLLOW_UP_TWELVE:"Urinalysis",POSSIBLE_FOLLOW_UP_THIRTEEN:"Organ-targeted imaging (e.g., CT thorax, CT abdomen)",POSSIBLE_FOLLOW_UP_FOURTEEN:"Blood tests: full blood count, renal and liver function, fasting glucose and insulin, HbA1c, HOMA-IR",POSSIBLE_FOLLOW_UP_FIFTEEN:"Lipid profile blood tests: basic and extended (incl. oxLDL, VLDL, LDL-P, Lp-PLA2, Lp(a), ApoB))",POSSIBLE_FOLLOW_UP_SIXTEEN:"Other blood tests hsCRP, homocysteine, renal and liver function, HbA1c",POSSIBLE_FOLLOW_UP_SEVENTEEN:"Blood tests: full blood count",POSSIBLE_FOLLOW_UP_EIGHTEEN:"Spirometry",POSSIBLE_FOLLOW_UP_NINETEEN:"ECG, chest X-ray",POSSIBLE_FOLLOW_UP_TWENTY:"Blood tests (incl. FSH, oestradiol, progesterone, testosterone, AMH)",POSSIBLE_FOLLOW_UP_TWENTYONE:"Referral to (peri)menopause specialist",POSSIBLE_FOLLOW_UP_TWENTYTWO:"Blood tests: full blood count, rheumatoid factor, anti-CCP antibodies, CRP",POSSIBLE_FOLLOW_UP_TWENTYTHREE:"Joint imaging (X-rays, MRI)",RISK_FACTORS:"Risk factors",RISK_FACTOR_ONE:"Past medical history (cardiometabolic syndrome, autoimmune disease)",RISK_FACTOR_TWO:"Medication history (e.g., statins, blood thinners)",RISK_FACTOR_THREE:"Current/previous smoking history",RELATED_RESEARCH_PAPERS:"Related research papers"},x={BIOLOGICAL_AGE:"Wiek biologiczny",GLYCAN:"Glikan",PEAK:"Pik",LOWER_THAN_AVERAGE:"ni\u017Cszy od warto\u015Bci \u015Bredniej",AROUND_AVERAGE:"W okolicach warto\u015Bci \u015Bredniej",HIGHER_THAN_AVERAGE:"wy\u017Cszy od warto\u015Bci \u015Bredniej",SOME_OVERLAP_LONG:"Nieznaczne nak\u0142adanie si\u0119",MINOR_OVERLAP_LONG:"Nieznaczne nak\u0142adanie si\u0119",NO_OVERLAP_LONG:"Brak nak\u0142adania si\u0119",SOME_OVERLAP:"Cz\u0119\u015Bciowy",MINOR_OVERLAP:"Niewielki",NO_OVERLAP:"Brak",OVERLAP_TEXT:"indeks\xF3w glikanowych mi\u0119dzy pacjentem a badanymi z tym schorzeniem.",SYMPTOMS:"Sygna\u0142y i objawy",SYMPTOM_ONE:"Przewa\u017Cnie przebiega w spos\xF3b bezobjawowy",SYMPTOM_TWO:"Ci\u015Bnienie t\u0119tnicze stale >140/90 mmHg",SYMPTOM_THREE:"Objawy nadci\u015Bnienia z\u0142o\u015Bliwego (b\xF3l g\u0142owy, zawroty g\u0142owy, duszno\u015B\u0107 itp.)",SYMPTOM_FOUR:"Objawy choroby wie\u0144cowej (np. samoistnie ust\u0119puj\u0105cy b\xF3l w klatce piersiowej, bezdech)",SYMPTOM_FIVE:"Objawy choroby t\u0119tnic obwodowych (np. b\xF3l n\xF3g podczas aktywno\u015Bci)",SYMPTOM_SIX:"Samoograniczaj\u0105cy si\u0119 b\xF3l w klatce piersiowej \xB1 promieniuj\u0105cy do szcz\u0119ki/lewego ramienia/plec\xF3w",SYMPTOM_SEVEN:"Duszno\u015B\u0107",SYMPTOM_EIGHT:"Inne (omdlenia, ko\u0142atanie serca, obrz\u0119k n\xF3g, orhhopnoe itp.)",SYMPTOM_NINE:"B\xF3l brzucha i skurcze",SYMPTOM_TEN:"Nawracaj\u0105ca biegunka (\xB1 krew)",SYMPTOM_ELEVEN:"Utrata masy cia\u0142a",SYMPTOM_TWELVE:"Og\xF3lnoustrojowe (np. zm\u0119czenie, utrata masy cia\u0142a, owrzodzenia jamy ustnej, wysypka w kszta\u0142cie motyla w okolicy policzk\xF3w i nosa)",SYMPTOM_THIRTEEN:"Narz\u0105dowe (b\xF3l w klatce piersiowej, trudno\u015Bci w oddychaniu, obrz\u0119k n\xF3g, niedokrwisto\u015B\u0107 itp.)",SYMPTOM_FOURTEEN:"B\xF3l i obrz\u0119k staw\xF3w",SYMPTOM_FIFTEEN:"Zm\u0119czenie",SYMPTOM_SIXTEEN:"Zwi\u0119kszone pragnienie i cz\u0119ste oddawanie moczu",SYMPTOM_SEVENTEEN:"Powolne gojenie si\u0119 ran, niewyra\u017Ane widzenie, cz\u0119ste ple\u015Bniawki",SYMPTOM_EIGHTEEN:"Trudno\u015Bci w oddychaniu",SYMPTOM_NINETEEN:"Przewlek\u0142y kaszel (\xB1 produktywny)",SYMPTOM_TWENTY:"Nieregularny cykl menstruacyjny",SYMPTOM_TWENTYONE:"Objawy naczynioruchowe (np. uderzenia gor\u0105ca)",SYMPTOM_TWENTYTWO:"Inne (np. wahania nastroju, trudno\u015Bci poznawcze, zaburzenia snu)",SYMPTOM_TWENTYTHREE:"Joint pain, swelling, stiffness and erythema",SYMPTOM_TWENTYFOUR:"Smaller and distant joint involvement (fingers, toes), usually symmetrical",SYMPTOM_TWENTYFIVE:"Systemic (fatigue, weight loss, etc.)",POSSIBLE_FOLLOW_UP:"Ewentualne dalsze dzia\u0142ania",POSSIBLE_FOLLOW_UP_ONE:"Seryjne pomiary ci\u015Bnienia t\u0119tniczego i/lub 24-godzinne monitorowanie ci\u015Bnienia t\u0119tniczego",POSSIBLE_FOLLOW_UP_TWO:"BMI i/lub kontrola sk\u0142adu cia\u0142a",POSSIBLE_FOLLOW_UP_THREE:"Podstawowe badania krwi (profil lipidowy, czynno\u015B\u0107 nerek i w\u0105troby)",POSSIBLE_FOLLOW_UP_FOUR:"Badania krwi: podstawowy i rozszerzony profil lipidowy (np. Lp(a), ApoB), hsCRP, homocysteina, czynno\u015B\u0107 nerek i w\u0105troby, HbA1c",POSSIBLE_FOLLOW_UP_FIVE:"Kontrola ci\u015Bnienia t\u0119tniczego",POSSIBLE_FOLLOW_UP_SIX:"EKG",POSSIBLE_FOLLOW_UP_SEVEN:"Skierowanie do kardiologa na inne badania (np. echo serca, TK naczy\u0144 wie\u0144cowych)",POSSIBLE_FOLLOW_UP_EIGHT:"Badania krwi: pe\u0142na morfologia krwi, czynno\u015B\u0107 nerek i w\u0105troby, CRP",POSSIBLE_FOLLOW_UP_NINE:"Badania ka\u0142u: test na obecno\u015B\u0107 krwi utajonej (FIT), kalprotektyna w kale",POSSIBLE_FOLLOW_UP_TEN:"Skierowanie na kolonoskopi\u0119, TK",POSSIBLE_FOLLOW_UP_ELEVEN:"Badania krwi: pe\u0142na morfologia krwi, czynno\u015B\u0107 nerek i w\u0105troby, CRP, OB, autoprzeciwcia\u0142a (np. ANA, w tym anty-dsDNA).",POSSIBLE_FOLLOW_UP_TWELVE:"Badanie og\xF3lne moczu",POSSIBLE_FOLLOW_UP_THIRTEEN:"Badania obrazowe ukierunkowane na narz\u0105dy (np. TK klatki piersiowej, TK jamy brzusznej)",POSSIBLE_FOLLOW_UP_FOURTEEN:"Badania krwi: pe\u0142na morfologia krwi, czynno\u015B\u0107 nerek i w\u0105troby, st\u0119\u017Cenie glukozy i insuliny na czczo, HbA1c, HOMA-IR",POSSIBLE_FOLLOW_UP_FIFTEEN:"Badania profilu lipidowego krwi: podstawowe i rozszerzone (np. oxLDL, Lp(a), ApoB))",POSSIBLE_FOLLOW_UP_SIXTEEN:"Inne badania krwi hsCRP, homocysteina, czynno\u015B\u0107 nerek i w\u0105troby, HbA1c",POSSIBLE_FOLLOW_UP_SEVENTEEN:"Badania krwi: pe\u0142na morfologia krwi",POSSIBLE_FOLLOW_UP_EIGHTEEN:"Spirometria",POSSIBLE_FOLLOW_UP_NINETEEN:"EKG, RTG klatki piersiowej",POSSIBLE_FOLLOW_UP_TWENTY:"Badania krwi (w tym FSH, estradiol, progesteron, testosteron, AMH)",POSSIBLE_FOLLOW_UP_TWENTYONE:"Skierowanie do specjalisty/ginekologa zajmuj\u0105cego si\u0119 (peri)menopauz\u0105",POSSIBLE_FOLLOW_UP_TWENTYTWO:"Badania krwi: pe\u0142na morfologia krwi, czynnik reumatoidalny, przeciwcia\u0142a anty-CCP, CRP",POSSIBLE_FOLLOW_UP_TWENTYTHREE:"Obrazowanie staw\xF3w (zdj\u0119cia rentgenowskie, rezonans magnetyczny)",RISK_FACTORS:"Czynniki ryzyka",RISK_FACTOR_ONE:"Historia chor\xF3b (np. zesp\xF3\u0142 kardiometaboliczny, choroby autoimmunologiczne)",RISK_FACTOR_TWO:"Historia przyjmowania lek\xF3w (np. statyn, lek\xF3w przeciwzakrzepowych)",RISK_FACTOR_THREE:"Palenie tytoniu",RELATED_RESEARCH_PAPERS:"Publikacje naukowe"};function Te(e){if(e===11||e===12||e===13)return"th";switch(e.toString().split("").pop()){case"1":return"st";case"2":return"nd";case"3":return"rd";default:return"th"}}function ye(e,t="english"){const n={english:G,polish:x};if(e<32)return n[t].LOWER_THAN_AVERAGE;if(e>=32&&e<=68)return n[t].AROUND_AVERAGE;if(e>68)return n[t].HIGHER_THAN_AVERAGE}function we(e="english",t){return{english:G,polish:x}[e][t]}export{C as A,Te as B,Pe as S,q as a,te as b,fe as c,ne as d,y as e,b as f,F as g,de as h,Le as i,H as j,T as k,_e as l,ye as m,we as n,ce as o,w as p,ae as q,Y as r,X as s,he as t,W as u,ie as v,f as w,ee as x,Se as y,j as z};
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