@glycanage/web-components 1.48.0 → 1.50.0
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
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import{c as J,S as Q,i as _,f as V,s as ee,a as le,e as w,b,d as E,g as T,t as A,h as S,j as L,k as q,o as te,l as D,m as G,n as x,p as r,q as n,r as B,u as N,v as M,w as C,x as H,y as k}from"./index2.js";import{g as se,A as R}from"./Arrow.js";function ie(f){le(f,"svelte-1285zfm",".summaryMain.svelte-1285zfm.svelte-1285zfm{padding:0 48px;height:100%;display:flex;flex-direction:column;color:#09341FCC}.summaryMain.svelte-1285zfm hr.svelte-1285zfm{border:2px solid rgba(201, 219, 210, 1);border-radius:2px;margin:18px 0}.summaryMain.svelte-1285zfm h5.svelte-1285zfm{font-size:16px;margin:0}.summaryMain.svelte-1285zfm ul.svelte-1285zfm{margin-top:4px;margin-bottom:24px;font-size:14px;padding-left:20px}.summaryMain.svelte-1285zfm ul li.svelte-1285zfm:not(:first-child){margin-top:4px}.summaryHeader.svelte-1285zfm.svelte-1285zfm{width:100%;font-size:16px;line-height:115%;padding-top:32px;display:flex;align-items:center;transform:translateX(-48px)}.summaryBody.svelte-1285zfm.svelte-1285zfm{width:100%;height:100%;margin:auto}.summaryBody.svelte-1285zfm a.svelte-1285zfm{display:block;color:#E66439;font-weight:bold;font-size:12px;margin-top:12px}.summaryBody.svelte-1285zfm p.svelte-1285zfm{color:rgba(9, 52, 31, 0.80);font-size:10px;margin-top:6px}.main.svelte-1285zfm.svelte-1285zfm{height:100%;width:100%;display:flex}.label.svelte-1285zfm.svelte-1285zfm{width:30%;display:flex;align-items:center}.header.svelte-1285zfm.svelte-1285zfm{width:100%;height:100%;display:flex;align-items:center}")}function ne(f){let e,l,t,m,v,z,i=f[1]==="mature"&&j(f),p=f[1]==="median"&&O(f),u=f[1]==="youth"&&U(f),d=f[1]==="shield"&&K(f),c=f[1]==="lifestyle"&&W(f);return{c(){i&&i.c(),e=b(),p&&p.c(),l=b(),u&&u.c(),t=b(),d&&d.c(),m=b(),c&&c.c(),v=E()},m(a,s){i&&i.m(a,s),T(a,e,s),p&&p.m(a,s),T(a,l,s),u&&u.m(a,s),T(a,t,s),d&&d.m(a,s),T(a,m,s),c&&c.m(a,s),T(a,v,s),z=!0},p(a,s){a[1]==="mature"?i?(i.p(a,s),s&2&&L(i,1)):(i=j(a),i.c(),L(i,1),i.m(e.parentNode,e)):i&&(D(),A(i,1,1,()=>{i=null}),S()),a[1]==="median"?p?(p.p(a,s),s&2&&L(p,1)):(p=O(a),p.c(),L(p,1),p.m(l.parentNode,l)):p&&(D(),A(p,1,1,()=>{p=null}),S()),a[1]==="youth"?u?(u.p(a,s),s&2&&L(u,1)):(u=U(a),u.c(),L(u,1),u.m(t.parentNode,t)):u&&(D(),A(u,1,1,()=>{u=null}),S()),a[1]==="shield"?d?(d.p(a,s),s&2&&L(d,1)):(d=K(a),d.c(),L(d,1),d.m(m.parentNode,m)):d&&(D(),A(d,1,1,()=>{d=null}),S()),a[1]==="lifestyle"?c?(c.p(a,s),s&2&&L(c,1)):(c=W(a),c.c(),L(c,1),c.m(v.parentNode,v)):c&&(D(),A(c,1,1,()=>{c=null}),S())},i(a){z||(L(i),L(p),L(u),L(d),L(c),z=!0)},o(a){A(i),A(p),A(u),A(d),A(c),z=!1},d(a){a&&(q(e),q(l),q(t),q(m),q(v)),i&&i.d(a),p&&p.d(a),u&&u.d(a),d&&d.d(a),c&&c.d(a)}}}function re(f){let e,l,t,m,v,z,i=f[2]?"Major overlap":f[3]?"Some overlap":"No significant overlap",p,u,d,c,a,s;function h(g,$){return g[2]||g[3]?me:oe}let y=h(f),o=y(f);return{c(){e=w("div"),l=w("div"),t=w("div"),o.c(),m=b(),v=w("div"),z=w("b"),p=G(i),u=G(" of glycan indexes between your patient and this condition."),d=b(),c=w("hr"),a=b(),s=w("div"),s.innerHTML='<h5 class="svelte-1285zfm">Signs and symptoms</h5> <ul class="svelte-1285zfm"><li class="svelte-1285zfm">Usually asymptomatic</li> <li class="svelte-1285zfm">Signs of coronary artery disease (e.g., self-resolving chest pain,
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import{c as J,S as Q,i as _,f as V,s as ee,a as le,e as w,b,d as E,g as T,t as A,h as S,j as L,k as q,o as te,l as D,m as G,n as x,p as r,q as n,r as B,u as N,v as M,w as C,x as H,y as k}from"./index2.js";import{g as se,A as R}from"./Arrow.js";function ie(f){le(f,"svelte-1285zfm",".summaryMain.svelte-1285zfm.svelte-1285zfm{padding:0 48px;height:100%;display:flex;flex-direction:column;color:#09341FCC}.summaryMain.svelte-1285zfm hr.svelte-1285zfm{border:2px solid rgba(201, 219, 210, 1);border-radius:2px;margin:18px 0}.summaryMain.svelte-1285zfm h5.svelte-1285zfm{font-size:16px;margin:0}.summaryMain.svelte-1285zfm ul.svelte-1285zfm{margin-top:4px;margin-bottom:24px;font-size:14px;padding-left:20px}.summaryMain.svelte-1285zfm ul li.svelte-1285zfm:not(:first-child){margin-top:4px}.summaryHeader.svelte-1285zfm.svelte-1285zfm{width:100%;font-size:16px;line-height:115%;padding-top:32px;display:flex;align-items:center;transform:translateX(-48px)}.summaryBody.svelte-1285zfm.svelte-1285zfm{width:100%;height:100%;margin:auto}.summaryBody.svelte-1285zfm a.svelte-1285zfm{display:block;color:#E66439;font-weight:bold;font-size:12px;margin-top:12px}.summaryBody.svelte-1285zfm p.svelte-1285zfm{color:rgba(9, 52, 31, 0.80);font-size:10px;margin-top:6px}.main.svelte-1285zfm.svelte-1285zfm{height:100%;width:100%;display:flex}.label.svelte-1285zfm.svelte-1285zfm{width:30%;display:flex;align-items:center}.header.svelte-1285zfm.svelte-1285zfm{width:100%;height:100%;display:flex;align-items:center}")}function ne(f){let e,l,t,m,v,z,i=f[1]==="mature"&&j(f),p=f[1]==="median"&&O(f),u=f[1]==="youth"&&U(f),d=f[1]==="shield"&&K(f),c=f[1]==="lifestyle"&&W(f);return{c(){i&&i.c(),e=b(),p&&p.c(),l=b(),u&&u.c(),t=b(),d&&d.c(),m=b(),c&&c.c(),v=E()},m(a,s){i&&i.m(a,s),T(a,e,s),p&&p.m(a,s),T(a,l,s),u&&u.m(a,s),T(a,t,s),d&&d.m(a,s),T(a,m,s),c&&c.m(a,s),T(a,v,s),z=!0},p(a,s){a[1]==="mature"?i?(i.p(a,s),s&2&&L(i,1)):(i=j(a),i.c(),L(i,1),i.m(e.parentNode,e)):i&&(D(),A(i,1,1,()=>{i=null}),S()),a[1]==="median"?p?(p.p(a,s),s&2&&L(p,1)):(p=O(a),p.c(),L(p,1),p.m(l.parentNode,l)):p&&(D(),A(p,1,1,()=>{p=null}),S()),a[1]==="youth"?u?(u.p(a,s),s&2&&L(u,1)):(u=U(a),u.c(),L(u,1),u.m(t.parentNode,t)):u&&(D(),A(u,1,1,()=>{u=null}),S()),a[1]==="shield"?d?(d.p(a,s),s&2&&L(d,1)):(d=K(a),d.c(),L(d,1),d.m(m.parentNode,m)):d&&(D(),A(d,1,1,()=>{d=null}),S()),a[1]==="lifestyle"?c?(c.p(a,s),s&2&&L(c,1)):(c=W(a),c.c(),L(c,1),c.m(v.parentNode,v)):c&&(D(),A(c,1,1,()=>{c=null}),S())},i(a){z||(L(i),L(p),L(u),L(d),L(c),z=!0)},o(a){A(i),A(p),A(u),A(d),A(c),z=!1},d(a){a&&(q(e),q(l),q(t),q(m),q(v)),i&&i.d(a),p&&p.d(a),u&&u.d(a),d&&d.d(a),c&&c.d(a)}}}function re(f){let e,l,t,m,v,z,i=f[2]?"Major overlap":f[3]?"Some overlap":"No significant overlap",p,u,d,c,a,s;function h(g,$){return g[2]||g[3]?me:oe}let y=h(f),o=y(f);return{c(){e=w("div"),l=w("div"),t=w("div"),o.c(),m=b(),v=w("div"),z=w("b"),p=G(i),u=G(" of glycan indexes between your patient and this condition."),d=b(),c=w("hr"),a=b(),s=w("div"),s.innerHTML='<h5 class="svelte-1285zfm">Signs and symptoms</h5> <ul class="svelte-1285zfm"><li class="svelte-1285zfm">Usually asymptomatic</li> <li class="svelte-1285zfm">Signs of coronary artery disease (e.g., self-resolving chest pain, breathlessness)</li> <li class="svelte-1285zfm">Signs of peripheral artery disease (e.g., leg pain during activity)</li></ul> <h5 class="svelte-1285zfm">Possible follow-up</h5> <ul class="svelte-1285zfm"><li class="svelte-1285zfm">Blood tests: basic and extended lipid profile (e.g., Lp(a), ApoB), hsCRP, homocysteine, renal and liver function, HbA1c</li> <li class="svelte-1285zfm">BP check</li> <li class="svelte-1285zfm">ECG</li> <li class="svelte-1285zfm">Cardiology referral for other tests (e.g., coronary artery calcium score)</li></ul> <h5 class="svelte-1285zfm">Related research papers</h5> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970566/pdf/res-122-1555.pdf" class="svelte-1285zfm">Glycosylation Profile of Immunoglobulin G Is Cross-Sectionally Associated With Cardiovascular Disease Risk Score and Subclinical Atherosclerosis in Two Independent Cohorts</a> <p class="svelte-1285zfm">In a study involving 2970 women aged 40\u201379 from the TwinsUK cohort, IgG glycosylation was examined in relation to the estimated 10-year risk of atherosclerotic cardiovascular disease and the presence of carotid and femoral plaque. A decrease in G1, G2 and S was observed, alongside an increase in G0 and B. These findings were replicated in 967 women from the ORCADES cohort (Orkney Complex Disease Study). Additionally, some of these glycan changes were also associated with 845 men in the study.</p>',x(t,"transform","translate(-50%)"),x(z,"color",f[2]||f[3]?"#F2590D":"#12A195"),r(l,"class","summaryHeader svelte-1285zfm"),r(c,"class","svelte-1285zfm"),r(s,"class","summaryBody svelte-1285zfm"),r(e,"class","summaryMain svelte-1285zfm")},m(g,$){T(g,e,$),n(e,l),n(l,t),o.m(t,null),n(l,m),n(l,v),n(v,z),n(z,p),n(v,u),n(e,d),n(e,c),n(e,a),n(e,s)},p(g,$){y!==(y=h(g))&&(o.d(1),o=y(g),o&&(o.c(),o.m(t,null))),$&12&&i!==(i=g[2]?"Major overlap":g[3]?"Some overlap":"No significant overlap")&&B(p,i),$&12&&x(z,"color",g[2]||g[3]?"#F2590D":"#12A195")},i:N,o:N,d(g){g&&q(e),o.d()}}}function ae(f){let e,l,t,m,v,z,i,p=f[2]?"Some overlap":f[3]?"Minor overlap":"No significant overlap",u;function d(s,h){return s[2]||s[3]?pe:de}let c=d(f),a=c(f);return{c(){e=w("div"),l=w("div"),t=w("b"),m=G(f[8]),v=G("/5"),z=b(),a.c(),i=G(`
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\xA0\xA0`),u=G(p),x(l,"padding-right","10px"),r(e,"class","header svelte-1285zfm")},m(s,h){T(s,e,h),n(e,l),n(l,t),n(t,m),n(t,v),n(e,z),a.m(e,null),n(e,i),n(e,u)},p(s,h){h&256&&B(m,s[8]),c===(c=d(s))&&a?a.p(s,h):(a.d(1),a=c(s),a&&(a.c(),a.m(e,i))),h&12&&p!==(p=s[2]?"Some overlap":s[3]?"Minor overlap":"No significant overlap")&&B(u,p)},i:N,o:N,d(s){s&&q(e),a.d()}}}function j(f){let e,l,t,m,v,z,i,p,u,d,c,a,s,h,y;return h=new R({props:{type:"right",percentile:f[7]}}),{c(){e=w("div"),l=w("div"),t=M("svg"),m=M("path"),z=b(),i=w("div"),p=w("div"),p.innerHTML="Glycan <b>Mature (G0)</b>",u=b(),d=w("div"),c=G(f[6]),a=b(),s=w("div"),C(h.$$.fragment),r(m,"fill",v=f[7]<=68?"#12A195":"#F2590D"),r(m,"d","m8.6 22.5l-1.9-3.2l-3.6-.8l.35-3.7L1 12l2.45-2.8l-.35-3.7l3.6-.8l1.9-3.2L12 2.95l3.4-1.45l1.9 3.2l3.6.8l-.35 3.7L23 12l-2.45 2.8l.35 3.7l-3.6.8l-1.9 3.2l-3.4-1.45l-3.4 1.45ZM12 17q.425 0 .713-.288T13 16q0-.425-.288-.713T12 15q-.425 0-.713.288T11 16q0 .425.288.713T12 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