@genome-spy/core 0.64.0 → 0.65.0

package/dist/bundle/index.js

@@ -1,35 +1,35 @@
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  * Copyright 2017 Google LLC
  * SPDX-License-Identifier: BSD-3-Clause
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- */const bg="important",fS=" !"+bg,hS=lS(class extends uS{constructor(t){var e;if(super(t),t.type!==cS.ATTRIBUTE||t.name!=="style"||((e=t.strings)==null?void 0:e.length)>2)throw Error("The `styleMap` directive must be used in the `style` attribute and must be the only part in the attribute.")}render(t){return Object.keys(t).reduce((e,n)=>{const r=t[n];return r==null?e:e+`${n=n.includes("-")?n:n.replace(/(?:^(webkit|moz|ms|o)|)(?=[A-Z])/g,"-$&").toLowerCase()}:${r};`},"")}update(t,[e]){const{style:n}=t.element;if(this.ft===void 0)return this.ft=new Set(Object.keys(e)),this.render(e);for(const r of this.ft)e[r]==null&&(this.ft.delete(r),r.includes("-")?n.removeProperty(r):n[r]=null);for(const r in e){const o=e[r];if(o!=null){this.ft.add(r);const i=typeof o=="string"&&o.endsWith(fS);r.includes("-")||i?n.setProperty(r,i?o.slice(0,-11):o,i?bg:""):n[r]=o}}return Jr}}),dS="data:image/svg+xml,%3csvg%20width='24'%20height='24'%20viewBox='0%200%2024%2024'%20xmlns='http://www.w3.org/2000/svg'%3e%3cstyle%3e.spinner_ajPY{transform-origin:center;animation:spinner_AtaB%20.75s%20infinite%20linear}@keyframes%20spinner_AtaB{100%25{transform:rotate(360deg)}}%3c/style%3e%3cpath%20d='M12,1A11,11,0,1,0,23,12,11,11,0,0,0,12,1Zm0,19a8,8,0,1,1,8-8A8,8,0,0,1,12,20Z'%20opacity='.25'/%3e%3cpath%20d='M10.14,1.16a11,11,0,0,0-9,8.92A1.59,1.59,0,0,0,2.46,12,1.52,1.52,0,0,0,4.11,10.7a8,8,0,0,1,6.66-6.61A1.42,1.42,0,0,0,12,2.69h0A1.57,1.57,0,0,0,10.14,1.16Z'%20class='spinner_ajPY'/%3e%3c/svg%3e",pS=`
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 :root {
 --genome-spy-basic-spacing: 10px;
 --genome-spy-font-family: system-ui, "Segoe UI", Roboto, Helvetica, Arial,
@@ -302,9 +302,9 @@ flex-basis: content;
 font-size: 14px;
 padding: var(--genome-spy-basic-spacing);
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i=gC,s=n.createFramebuffer();n.bindFramebuffer(i,s),t=t||n.drawingBufferWidth,r=r||n.drawingBufferHeight,e=e||nm;const o=[],a={framebuffer:s,attachments:[],width:t,height:r};return e.forEach(function(c,u){let l=c.attachment;const f=c.samples,d=c.format;let h=c.attachmentPoint||TC(d,c.internalFormat);if(h||(h=Gl+u),FC(h)&&o.push(h),!l)if(f!==void 0||BC(d))l=n.createRenderbuffer(),n.bindRenderbuffer(vr,l),f>1?n.renderbufferStorageMultisample(vr,f,d,t,r):n.renderbufferStorage(vr,d,t,r);else{const p=Object.assign({},c);p.width=t,p.height=r,p.auto===void 0&&(p.auto=!1,p.min=p.min||p.minMag||_l,p.mag=p.mag||p.minMag||_l,p.wrapS=p.wrapS||p.wrap||Vl,p.wrapT=p.wrapT||p.wrap||Vl),l=oo(n,p)}if(q0(n,l))n.framebufferRenderbuffer(i,h,vr,l);else if(tc(n,l))c.layer!==void 0?n.framebufferTextureLayer(i,h,l,c.level||0,c.layer):n.framebufferTexture2D(i,h,c.target||yC,l,c.level||0);else throw new Error("unknown attachment type");a.attachments.push(l)}),n.drawBuffers&&n.drawBuffers(o),a}function PC(n,e,t,r,i){r=r||n.drawingBufferWidth,i=i||n.drawingBufferHeight,e.width=r,e.height=i,t=t||nm,t.forEach(function(s,o){const a=e.attachments[o],c=s.format,u=s.samples;if(u!==void 0||q0(n,a))n.bindRenderbuffer(vr,a),u>1?n.renderbufferStorageMultisample(vr,u,c,r,i):n.renderbufferStorage(vr,c,r,i);else if(tc(n,a))aE(n,a,s,r,i);else throw new Error("unknown attachment type")})}function MC(n,e,t){const r=n.createVertexArray();return n.bindVertexArray(r),e.length||(e=[e]),e.forEach(function(i){wr(n,i,t)}),n.bindVertexArray(null),{numElements:t.numElements,elementType:t.elementType,vertexArrayObject:r}}const RC=/^(.*?)_/;function OC(n,e){Sl(n,0);const t=n.getExtension(e);if(t){const r={},i=RC.exec(e)[1],s="_"+i;for(const o in t){const a=t[o],c=typeof a=="function",u=c?i:s;let l=o;o.endsWith(u)&&(l=o.substring(0,o.length-u.length)),n[l]!==void 0?!c&&n[l]!==a&&W0(l,n[l],a,o):c?n[l]=function(f){return function(){return f.apply(t,arguments)}}(a):(n[l]=a,r[l]=a)}r.constructor={name:t.constructor.name},Sl(r,0)}return t}const im=["ANGLE_instanced_arrays","EXT_blend_minmax","EXT_color_buffer_float","EXT_color_buffer_half_float","EXT_disjoint_timer_query","EXT_disjoint_timer_query_webgl2","EXT_frag_depth","EXT_sRGB","EXT_shader_texture_lod","EXT_texture_filter_anisotropic","OES_element_index_uint","OES_standard_derivatives","OES_texture_float","OES_texture_float_linear","OES_texture_half_float","OES_texture_half_float_linear","OES_vertex_array_object","WEBGL_color_buffer_float","WEBGL_compressed_texture_atc","WEBGL_compressed_texture_etc1","WEBGL_compressed_texture_pvrtc","WEBGL_compressed_texture_s3tc","WEBGL_compressed_texture_s3tc_srgb","WEBGL_depth_texture","WEBGL_draw_buffers"];function sm(n){for(let e=0;e<im.length;++e)OC(n,im[e])}function NC(n,e){const t=["webgl2","webgl","experimental-webgl"];let r=null;for(let i=0;i<t.length;++i)if(r=n.getContext(t[i],e),r){sm(r);break}return r}function LC(n,e){return NC(n,e)}const zC=`flat out lowp vec4 vFillColor;flat out lowp vec4 vStrokeColor;flat out float vHalfStrokeWidth;flat out vec4 vCornerRadii;
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 out vec2 vPosInPixels;
 #endif
@@ -312,7 +312,7 @@ flat out vec2 vHalfSizeInPixels;/***Adjusts the vertex position to ensure that t
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+gl_Position=unitToNdc(pos);float fillOpacity=getScaled_fillOpacity()*opaFactor;vFillColor=vec4(getScaled_fill()*fillOpacity,fillOpacity);setupPicking();}`,UC=`#if defined(ROUNDED_CORNERS) || defined(STROKED) || defined(SHADOW)
 in vec2 vPosInPixels;
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 flat in vec2 vHalfSizeInPixels;flat in lowp vec4 vFillColor;flat in lowp vec4 vStrokeColor;flat in float vHalfStrokeWidth;flat in vec4 vCornerRadii;out lowp vec4 fragColor;
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 #pragma markUniforms
-};`,Mm=1e4;class c8{constructor(e){he(this,jo);he(this,Ha,!1);this.size=e,this.arrays={},this.pushers=[],this.dataUpdaters=[],this.vertexCount=0}configure(){if(j(this,Ha))throw new Error("Already configured!");pe(this,jo,Nv).call(this),pe(this,jo,zv).call(this),Ae(this,Ha,!0)}addConverter(e,n){const r=this.createUpdater(e,n.numComponents||1,n.targetArrayType??Float32Array,n.arrayReference),o=n.f;this.dataUpdaters.push(n.arrayReference?i=>r(o(i)):i=>r(o(i)))}createUpdater(e,n,r=Float32Array,o=void 0){if(!Ht(this.size))throw new Error("The number of vertices must be defined!");let i,s,a=0;const c=new r(this.size*n);if(this.arrays[e]={data:c,numComponents:n},n==1){let l=0;const u=f=>{l=+f};i=()=>{c[a++]=l},s=u}else{let l=o??[0];const u=o?f=>{}:f=>{l=f};switch(n){case 1:break;case 2:i=()=>{c[a++]=l[0],c[a++]=l[1]},s=u;break;case 3:i=()=>{c[a++]=l[0],c[a++]=l[1],c[a++]=l[2]},s=u;break;case 4:i=()=>{c[a++]=l[0],c[a++]=l[1],c[a++]=l[2],c[a++]=l[3]},s=u;break;default:throw new Error("Invalid numComponents: "+n)}}return this.pushers.push(i),s}pushAll(){throw new Error("Call configure() first!")}updateFromDatum(e){throw new Error("Call configure() first!")}pushFromDatum(e){this.updateFromDatum(e),this.pushAll()}}Ha=new WeakMap,jo=new WeakSet,Nv=function(){if(this.size>Mm){const e=this.pushers.map((r,o)=>`const p${o} = that.pushers[${o}];`).join(`
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+`),t=this.pushers.map((r,i)=>`  p${i}();`).join(`
 `);this.pushAll=new Function("that",`${e}
 return function unrolledPushAll() {
-${n}
+${t}
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-`),n=this.dataUpdaters.map((r,o)=>`  u${o}(datum);`).join(`
+};`)(this)}else this.pushAll=()=>{for(let e=0;e<this.pushers.length;e++)this.pushers[e]();this.vertexCount++}},bx=function(){if(this.size>om){const e=this.dataUpdaters.map((r,i)=>`const u${i} = that.dataUpdaters[${i}];`).join(`
+`),t=this.dataUpdaters.map((r,i)=>`  u${i}(datum);`).join(`
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+${t}
+};`)(this)}else this.updateFromDatum=e=>{for(let t=0;t<this.dataUpdaters.length;t++)this.dataUpdaters[t](e)}};const co=5,jl=127;function Ql(n){const e=[];for(let p=0;p<=jl;p++)e.push(void 0);const t=new Map;for(const p of n.chars)p.id<=jl?e[p.id]=p:t.set(p.id,p);const r=8722;t.has(r)||t.set(r,e[45]);function i(p){return(p<=jl?e[p]:t.get(p))||e[63]}function s(p){return i(p.charCodeAt(0))}const o=n.common.base,a=s("x"),c=s("X"),u=s("q"),l=a.height-co*2,f=c.height-co*2,d=u.height-a.height+u.yoffset-a.yoffset;function h(p,m=1){let g=0;for(let y=0;y<p.length;y++)g+=i(p.charCodeAt(y)).xadvance;return g/o*m}return{measureWidth:h,getCharByCode:i,getChar:s,xHeight:l,capHeight:f,descent:d,common:n.common}}function vi(n,e=0,t=1){return Math.max(e,Math.min(t,n))}const am=2**31-1,VC=-2147483648;function _C(n,e,t,r=t){const i=new Array(n);i.fill(am);let s=VC,o=-1/0,a=!1;const c=new Array(n);c.fill(0);const u=e[0],f=(e[1]-e[0])/n,d=(y,x)=>{const A=(y-u)/f,w=Math.floor(A);return vi(x&&w==A?w-1:w,0,n-1)};function h(y,x,A){if(a)return;if(x>s)s=x;else{a=!0;return}const w=t(y);if(w<o){a=!0;return}o=w;const S=d(w,!1);i[S]>x&&(i[S]=x),c[S]<A&&(c[S]=A)}function p(y,x,A){if(a)return;if(x>s)s=x;else{a=!0,console.debug("Items (vertices) are not ordered properly. Disabling binned index.");return}const w=t(y),S=r(y);if(w<o){a=!0;return}else if(S<w){a=!0;return}o=w;const C=d(w,!1),v=d(S,!0);for(let T=C;T<=v;T++)i[T]>x&&(i[T]=x),c[T]<A&&(c[T]=A)}const m=(y,x,A=[0,0])=>{const w=d(y,!1),S=d(x,!0),C=i[w],v=Math.max(c[S],C);return A[0]=C,A[1]=v,A},g=()=>{if(a)return;for(let x=1;x<c.length;x++)c[x]<c[x-1]&&(c[x]=c[x-1]);let y=!0;for(let x=i.length-1;x>0;x--)y&&i[x]==am?(i[x]=c[x],y=!1):i[x-1]>i[x]&&(i[x-1]=i[x]);return m};return h.getIndex=g,p.getIndex=g,t==r?h:p}const Ht=1,Rn=2,Wl=4;class ql{constructor(e){R(this,Wr);Y(this,"stats",{count:0,first:null});Y(this,"paramMediatorProvider",null);this.paramMediatorProvider=e,this.children=[],this.parent=void 0,this.completed=!1}get behavior(){return 0}get label(){return`(${this.constructor.name})`}reset(){this.completed=!1;for(const e of this.children)e.reset();this.stats.count=0,this.stats.first=null}initialize(){}setParent(e){this.parent=e}addChild(e){if(e.parent)throw new Error("Cannot add the child! It already has a parent.");return this.children.push(e),e.setParent(this),O(this,Wr,Da).call(this),this}adopt(e){e.parent&&e.parent.removeChild(e),this.addChild(e)}adoptChildrenOf(e){for(const t of e.children)this.adopt(t)}insertAsParent(e){var t;if(this.isRoot())throw new Error("Cannot insert a new parent for a root node!");e.parent=this.parent,this.parent.children[this.parent.children.indexOf(this)]=e,O(t=this.parent,Wr,Da).call(t),this.parent=void 0,e.addChild(this)}removeChild(e){const t=this.children.indexOf(e);if(t>-1)this.children.splice(t,1),e.parent=void 0,O(this,Wr,Da).call(this);else throw new Error("Trying to remove an unknown child node!")}excise(){var e;if(this.isRoot())throw new Error("Cannot excise root node!");if(this.isTerminal())this.parent.removeChild(this);else if(this.children.length==1){const t=this.children[0];t.setParent(this.parent),this.parent.children[this.parent.children.indexOf(this)]=t,O(e=this.parent,Wr,Da).call(e),this.setParent(void 0),this.children.length=0}else throw new Error("Cannot excise a node that has multiple children!")}isRoot(){return!this.parent}isBranching(){return this.children.length>1}isTerminal(){return this.children.length==0}visit(e){e(this);for(const t of this.children)t.visit(e);e.afterChildren&&e.afterChildren(this)}subtreeToString(e=0){const t=this.children.map(r=>r.subtreeToString(e+1)).join("");return`${" ".repeat(e*2)}* ${this.label}${"identifier"in this&&this.identifier?": "+this.identifier:""} 
+${t}`}handle(e){this._propagate(e)}complete(){this.completed=!0;for(const e of this.children)e.complete()}beginBatch(e){for(const t of this.children)t.beginBatch(e)}get paramMediator(){if(this.paramMediatorProvider)return this.paramMediatorProvider.paramMediator;if(!this.parent)throw new Error("Cannot find paramMediator!");return this.parent.paramMediator}repropagate(){if(this.parent)this.parent.repropagate();else throw new Error("Cannot repropagate data, no FlowNode with stored data found!")}_propagate(e){}}Wr=new WeakSet,Da=function(){this._propagate=Function("children","stats",Us(this.children.length).map(e=>`const child${e} = children[${e}];`).join(`
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                     if (stats.count === 0) {
                         stats.first = structuredClone(datum);
                     }
                     stats.count++;
-                ${Is(this.children.length).map(e=>`child${e}.handle(datum);`).join(`
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     }`)}return r.join(`
-`)}function oD(){let t=0,e,n=0;const r=new Map,o=i=>(i===e||(n=r.get(i),n===void 0&&(n=t++,r.set(i,n)),e=i),n);return o.addAll=i=>{for(const s of i)o(s)},o.invert=i=>{for(const s of r.entries())if(s[1]==i)return s[0]},o.domain=()=>[...r.keys()],o}class xa{constructor({encoders:e,numVertices:n=void 0,attributes:r=[]}){this.encoders=e,this.variableEncoders=Object.fromEntries(Object.entries(e).filter(([i,s])=>r.includes(i)&&s&&!s.constant));const o=[...Jy(e).entries()].filter(([i,s])=>i[1]&&s.length>1).map(([i,s])=>s);this.allocatedVertices=n,this.variableBuilder=new c8(n);for(const[i,s]of Object.entries(this.variableEncoders)){const a=s.dataAccessor;if(!a)continue;const c=o.find(S=>S.find(E=>E==i));if(c&&i!=c[0])continue;const l=a.asNumberAccessor(),u=s.scale,{largeHp:f,arrayConstructor:d,discrete:h,numComponents:p}=wo(u,i),y=[0,0];let v;u&&h&&"domain"in u&&(v=oD(),v.addAll(u.domain()));const b=v?S=>v(a(S)):f?S=>Ky(l(S),y):l,A=xo(c??i);this.variableBuilder.addConverter(A,{f:b,numComponents:p,arrayReference:f?y:void 0,targetArrayType:d})}this.lastOffset=0,this.rangeMap=new Yn([],JSON.stringify)}registerBatch(e){var i;const n=this.lastOffset,r=this.variableBuilder.vertexCount,o=r-n;o&&this.rangeMap.set(e,{offset:n,count:o,xIndex:(i=this.xIndexer)==null?void 0:i.getIndex()}),this.lastOffset=r}addBatches(e){for(const[n,r]of e)this.addBatch(n,r)}addBatch(e,n,r=0,o=n.length){this.prepareXIndexer(n,r,o);for(let i=r;i<o;i++){const s=n[i];this.variableBuilder.pushFromDatum(s),this.addToXIndex(s)}this.registerBatch(e)}prepareXIndexer(e,n=0,r=n+e.length){var l;const o=()=>{this.addToXIndex=u=>{},this.xIndexer=void 0},i=(l=this.encoders.x)==null?void 0:l.channelDef;if(!("buildIndex"in i)||!i.buildIndex||!e.length||r-n<0){o();return}const s=u=>{var f;return u&&St((f=u.scale)==null?void 0:f.type)&&u},a=s(this.variableEncoders.x),c=s(this.variableEncoders.x2);if(a&&!a.constant&&(!c||!c.constant)){const u=a.dataAccessor.asNumberAccessor(),f=c?c.dataAccessor.asNumberAccessor():u,d=[u(e[n]),f(e[r-1])];if(d[1]>d[0]){this.xIndexer=u8(50,d,u,f);let h=this.variableBuilder.vertexCount;this.addToXIndex=p=>{let y=this.variableBuilder.vertexCount;this.xIndexer(p,h,y),h=y}}else o()}else o()}addToXIndex(e){}toArrays(){return{arrays:this.variableBuilder.arrays,vertexCount:this.variableBuilder.vertexCount,allocatedVertices:this.allocatedVertices,rangeMap:this.rangeMap}}}class sD extends xa{constructor({encoders:e,attributes:n,numItems:r}){super({encoders:e,attributes:n,numVertices:r*6}),this.variableBuilder.configure();const o=this.variableBuilder.pushAll;this.pushAllSixTimes=r>500?new Function("pushAll",`return function unrolledPushAllSixTimes() {
+`)}function z5(){let n=0,e,t=0;const r=new Map,i=s=>(s===e||(t=r.get(s),t===void 0&&(t=n++,r.set(s,t)),e=s),t);return i.addAll=s=>{for(const o of s)i(o)},i.invert=s=>{for(const o of r.entries())if(o[1]==s)return o[0]},i.domain=()=>[...r.keys()],i}class Ro{constructor({encoders:e,numVertices:t=void 0,attributes:r=[]}){this.encoders=e,this.variableEncoders=Object.fromEntries(Object.entries(e).filter(([s,o])=>r.includes(s)&&o&&!o.constant));const i=[...E1(e).entries()].filter(([s,o])=>s[1]&&o.length>1).map(([s,o])=>o);this.allocatedVertices=t,this.variableBuilder=new HC(t);for(const[s,o]of Object.entries(this.variableEncoders)){const a=o.dataAccessor;if(!a)continue;const c=i.find(A=>A.find(w=>w==s));if(c&&s!=c[0])continue;const u=a.asNumberAccessor(),l=o.scale,{largeHp:f,arrayConstructor:d,discrete:h,numComponents:p}=Fi(l,s),m=[0,0];let g;l&&h&&"domain"in l&&(g=z5(),g.addAll(l.domain()));const y=g?A=>g(a(A)):f?A=>S1(u(A),m):u,x=Pi(c??s);this.variableBuilder.addConverter(x,{f:y,numComponents:p,arrayReference:f?m:void 0,targetArrayType:d})}this.lastOffset=0,this.rangeMap=new tn([],JSON.stringify)}registerBatch(e){var s;const t=this.lastOffset,r=this.variableBuilder.vertexCount,i=r-t;i&&this.rangeMap.set(e,{offset:t,count:i,xIndex:(s=this.xIndexer)==null?void 0:s.getIndex()}),this.lastOffset=r}addBatches(e){for(const[t,r]of e)this.addBatch(t,r)}addBatch(e,t,r=0,i=t.length){this.prepareXIndexer(t,r,i);for(let s=r;s<i;s++){const o=t[s];this.variableBuilder.pushFromDatum(o),this.addToXIndex(o)}this.registerBatch(e)}prepareXIndexer(e,t=0,r=t+e.length){var u;const i=()=>{this.addToXIndex=l=>{},this.xIndexer=void 0},s=(u=this.encoders.x)==null?void 0:u.channelDef;if(!("buildIndex"in s)||!s.buildIndex||!e.length||r-t<0){i();return}const o=l=>{var f;return l&&Oe((f=l.scale)==null?void 0:f.type)&&l},a=o(this.variableEncoders.x),c=o(this.variableEncoders.x2);if(a&&!a.constant&&(!c||!c.constant)){const l=a.dataAccessor.asNumberAccessor(),f=c?c.dataAccessor.asNumberAccessor():l,d=[l(e[t]),f(e[r-1])];if(d[1]>d[0]){this.xIndexer=_C(50,d,l,f);let h=this.variableBuilder.vertexCount;this.addToXIndex=p=>{let m=this.variableBuilder.vertexCount;this.xIndexer(p,h,m),h=m}}else i()}else i()}addToXIndex(e){}toArrays(){return{arrays:this.variableBuilder.arrays,vertexCount:this.variableBuilder.vertexCount,allocatedVertices:this.allocatedVertices,rangeMap:this.rangeMap}}}class U5 extends Ro{constructor({encoders:e,attributes:t,numItems:r}){super({encoders:e,attributes:t,numVertices:r*6}),this.variableBuilder.configure();const i=this.variableBuilder.pushAll;this.pushAllSixTimes=r>500?new Function("pushAll",`return function unrolledPushAllSixTimes() {
   pushAll(); pushAll(); pushAll(); pushAll(); pushAll(); pushAll();
-};`)(o):function(){o(),o(),o(),o(),o(),o()}}addBatch(e,n,r=0,o=n.length){if(!(o<=r)){this.prepareXIndexer(n,r,o);for(let i=r;i<o;i++){const s=n[i];this.variableBuilder.updateFromDatum(s),this.pushAllSixTimes(),this.addToXIndex(s)}this.registerBatch(e)}}}class aD extends xa{constructor({encoders:e,attributes:n,tessellationThreshold:r=1/0,visibleRange:o=[-1/0,1/0],numItems:i}){super({encoders:e,attributes:n,numVertices:r==1/0?i*6:void 0}),this.visibleRange=o,this.tessellationThreshold=r||1/0,this.updateSide=this.variableBuilder.createUpdater("side",1),this.updatePos=this.variableBuilder.createUpdater("pos",1),this.variableBuilder.configure()}addBatch(e,n,r=0,o=n.length){this.prepareXIndexer(n,r,o);for(let i=r;i<o;i++){const s=n[i];this.variableBuilder.updateFromDatum(s),this.updateSide(-.5),this.updatePos(0),this.variableBuilder.pushAll();const a=1;for(let c=0;c<=a;c++)this.updatePos(c/a),this.updateSide(-.5),this.variableBuilder.pushAll(),this.updateSide(.5),this.variableBuilder.pushAll();this.variableBuilder.pushAll(),this.addToXIndex(s)}this.registerBatch(e)}}class cD extends xa{constructor({encoders:e,attributes:n,numItems:r=void 0}){super({encoders:e,attributes:n,numVertices:r}),this.variableBuilder.configure()}}class lD extends xa{constructor({encoders:e,attributes:n,numItems:r=void 0}){super({encoders:e,attributes:n,numVertices:r}),this.variableBuilder.configure()}toArrays(){const e=this.variableBuilder.arrays;for(let n of Object.values(e))n.divisor=1;return super.toArrays()}}class uD extends xa{constructor({encoders:e,attributes:n,fontMetrics:r,properties:o,numCharacters:i=void 0}){super({encoders:e,attributes:n,numVertices:i*6}),this.metadata=r,this.metrics=r,this.properties=o;const a=e.text.channelDef;this.numberFormat=!ln(a)&&"format"in a&&a.format?Dt(a.format):c=>c,this.updateVertexCoord=this.variableBuilder.createUpdater("vertexCoord",2),this.updateTextureCoord=this.variableBuilder.createUpdater("textureCoord",2),this.updateWidth=this.variableBuilder.createUpdater("width",1),this.variableBuilder.configure()}addBatch(e,n,r=0,o=n.length){const i=this.properties.align||"left",s=this.properties.logoLetters??!1,a=this.metadata.common.base,c=this.metadata.common.scaleH;let l=-5;switch(this.properties.baseline){case"top":l+=this.metrics.capHeight;break;case"middle":l+=this.metrics.capHeight/2;break;case"bottom":l-=this.metrics.descent;break}const u=this.encoders.text,f=[0,0];this.updateVertexCoord(f);const d=[0,0];this.updateTextureCoord(d),this.prepareXIndexer(n,r,o);for(let h=r;h<o;h++){const p=n[h],y=this.numberFormat(u(p)),v=rt(y)?y:y===null?"":""+y;if(v.length==0)continue;this.variableBuilder.updateFromDatum(p);const b=s?v.length:this.metrics.measureWidth(v);this.updateWidth(b);let A=i=="right"?-b:i=="center"?-b/2:0;if(!s){const _=this.metrics.getCharByCode(v.charCodeAt(0));A-=(_.width-_.xadvance)/a/2}let S=-.5,E=1,I=1;for(let _=0;_<v.length;_++){const B=this.metrics.getCharByCode(v.charCodeAt(_)),N=s?1:B.xadvance/a;if(B.id==32){A+=N;continue}s?(I=(B.width+Zs*2)/B.width,A=-I/2,E=(B.height+Zs*2)/B.height,S=-.5-Zs/B.height):(E=B.height/a,S=-(B.height+B.yoffset+l)/a,I=B.width/a);const F=B.x,M=B.y;f[0]=A,f[1]=S+E,d[0]=F/c,d[1]=M/c,this.variableBuilder.pushAll(),f[0]=A+I,f[1]=S+E,d[0]=(F+B.width)/c,d[1]=M/c,this.variableBuilder.pushAll(),f[0]=A,f[1]=S,d[0]=F/c,d[1]=(M+B.height)/c,this.variableBuilder.pushAll(),f[0]=A+I,f[1]=S+E,d[0]=(F+B.width)/c,d[1]=M/c,this.variableBuilder.pushAll(),f[0]=A,f[1]=S,d[0]=F/c,d[1]=(M+B.height)/c,this.variableBuilder.pushAll(),f[0]=A+I,f[1]=S,d[0]=(F+B.width)/c,d[1]=(M+B.height)/c,this.variableBuilder.pushAll(),A+=N}this.addToXIndex(p)}this.registerBatch(e)}}const eb=`#define PI 3.141593
-uniform View{mediump vec2 uViewOffset;mediump vec2 uViewScale;mediump vec2 uViewportSize;lowp float uDevicePixelRatio;lowp float uViewOpacity;bool uPickingEnabled;};/***Maps a coordinate on the unit scale to a normalized device coordinate.*(0,0)is at the bottom left corner.*/vec4 unitToNdc(vec2 coord){return vec4((coord*uViewScale+uViewOffset)*2.0-1.0,0.0,1.0);}vec4 unitToNdc(float x,float y){return unitToNdc(vec2(x,y));}vec4 pixelsToNdc(vec2 coord){return unitToNdc(coord/uViewportSize);}vec4 pixelsToNdc(float x,float y){return pixelsToNdc(vec2(x,y));}float linearstep(float edge0,float edge1,float x){return clamp((x-edge0)/(edge1-edge0),0.0,1.0);}bool isEmptyBinarySearchTexture(highp usampler2D s){return textureSize(s,0).x==1&&texelFetch(s,ivec2(0,0),0).r==0u;}bool binarySearchTexture(highp usampler2D s,uint value){int texSize=textureSize(s,0).x;if(texSize==1&&texelFetch(s,ivec2(0,0),0).r==0u){return false;}int left=0;int right=texSize-1;while(left<=right){int mid=left+(right-left)/2;uint midValue=texelFetch(s,ivec2(mid,0),0).r;if(midValue==value){return true;}if(midValue<value){left=mid+1;}else{right=mid-1;}}return false;}/***Calculates a gamma for antialiasing opacity based on the color.*/float getGammaForColor(vec3 rgb){return mix(1.25,0.75,smoothstep(0.0,1.0,dot(rgb,vec3(0.299,0.587,0.114))));}/***Specialized linearstep for doing antialiasing*/float distanceToRatio(float d){return clamp(d*uDevicePixelRatio+0.5,0.0,1.0);}vec4 distanceToColor(float d,vec4 fill,vec4 stroke,vec4 background,float halfStrokeWidth){if(halfStrokeWidth>0.0){float sd=abs(d)-halfStrokeWidth;return mix(stroke,d<=0.0 ? fill : background,distanceToRatio(sd));}else{return mix(background,fill,distanceToRatio(-d));}}`,fD="uniform highp float uZero;vec3 getDiscreteColor(sampler2D s,int index){return texelFetch(s,ivec2(index % textureSize(s,0).x,0),0).rgb;}vec3 getInterpolatedColor(sampler2D s,float unitValue){return texture(s,vec2(unitValue,0.0)).rgb;}float clampToRange(float value,vec2 range){return clamp(value,min(range[0],range[1]),max(range[0],range[1]));}float scaleIdentity(float value){return value;}float scaleIdentity(uint value){return float(value);}float scaleLinear(float value,vec2 domain,vec2 range){float domainSpan=domain[1]-domain[0];float rangeSpan=range[1]-range[0];return(value-domain[0])/domainSpan*rangeSpan+range[0];}float scaleLog(float value,vec2 domain,vec2 range,float base){return scaleLinear(log(value)/log(base),log(domain)/log(base),range);}float symlog(float value,float constant){return sign(value)*log(abs(value/constant)+1.0);}float scaleSymlog(float value,vec2 domain,vec2 range,float constant){return scaleLinear(symlog(value,constant),vec2(symlog(domain[0],constant),symlog(domain[1],constant)),range);}float scalePow(float value,vec2 domain,vec2 range,float exponent){return scaleLinear(pow(abs(value),exponent)*sign(value),pow(abs(domain),vec2(exponent))*sign(domain),range);}float scaleBand(uint value,vec2 domainExtent,vec2 range,float paddingInner,float paddingOuter,float align,float band){float start=range[0];float stop=range[1];float rangeSpan=stop-start;float n=domainExtent[1]-domainExtent[0];paddingInner=int(n)>1 ? paddingInner : 0.0;float step=rangeSpan/max(1.0,n-paddingInner+paddingOuter*2.0);start+=(rangeSpan-step*(n-paddingInner))*align;float bandwidth=step*(1.0-paddingInner);return start+(float(value)-domainExtent[0])*step+bandwidth*band;}const int lowBits=12;const float lowDivisor=pow(2.0,float(lowBits));const uint lowMask=uint(lowDivisor-1.0);vec2 splitUint(uint value){uint valueLo=value&lowMask;uint valueHi=value-valueLo;return vec2(float(valueHi),float(valueLo));}/***High precision variant of scaleBand for index/locus scales*/float scaleBandHp(uint value,vec3 domainExtent,vec2 range,float paddingInner,float paddingOuter,float align,float band){float start=range[0];float stop=range[1];float rangeSpan=stop-start;vec2 domainStart=domainExtent.xy;float n=domainExtent[2];float step=rangeSpan/max(1.0,n-paddingInner+paddingOuter*2.0);start+=(rangeSpan-step*(n-paddingInner))*align;float bandwidth=step*(1.0-paddingInner);vec2 splitValue=splitUint(value);float inf=1.0/uZero;float hi=max(splitValue[0]-domainStart[0],-inf);float lo=max(splitValue[1]-domainStart[1],-inf);return dot(vec4(start,hi,lo,bandwidth),vec4(1.0,step,step,band));}/***High precision variant of scaleBand for index/locus scales for large*domains where 32bit uints are not sufficient to represent the domain.*/float scaleBandHp(uvec2 value,vec3 domainExtent,vec2 range,float paddingInner,float paddingOuter,float align,float band){float start=range[0];float stop=range[1];float rangeSpan=stop-start;vec2 domainStart=domainExtent.xy;float n=domainExtent[2];float step=rangeSpan/max(1.0,n-paddingInner+paddingOuter*2.0);start+=(rangeSpan-step*(n-paddingInner))*align;float bandwidth=step*(1.0-paddingInner);vec2 splitValue=vec2(float(value[0])*lowDivisor,float(value[1]));float inf=1.0/uZero;float hi=max(splitValue[0]-domainStart[0],-inf);float lo=max(splitValue[1]-domainStart[1],-inf);return dot(vec4(start,hi,lo,bandwidth),vec4(1.0,step,step,band));}",hD=`/***Describes where a sample facet should be shown. Interpolating between the*current and target positions/heights allows for transitioning between facet*configurations.*/struct SampleFacetPosition{float pos;float height;float targetPos;float targetHeight;};/***Trasition fraction[0,1]between the current and target configurations.*/uniform float uTransitionOffset;
+};`)(i):function(){i(),i(),i(),i(),i(),i()}}addBatch(e,t,r=0,i=t.length){if(!(i<=r)){this.prepareXIndexer(t,r,i);for(let s=r;s<i;s++){const o=t[s];this.variableBuilder.updateFromDatum(o),this.pushAllSixTimes(),this.addToXIndex(o)}this.registerBatch(e)}}}class G5 extends Ro{constructor({encoders:e,attributes:t,tessellationThreshold:r=1/0,visibleRange:i=[-1/0,1/0],numItems:s}){super({encoders:e,attributes:t,numVertices:r==1/0?s*6:void 0}),this.visibleRange=i,this.tessellationThreshold=r||1/0,this.updateSide=this.variableBuilder.createUpdater("side",1),this.updatePos=this.variableBuilder.createUpdater("pos",1),this.variableBuilder.configure()}addBatch(e,t,r=0,i=t.length){this.prepareXIndexer(t,r,i);for(let s=r;s<i;s++){const o=t[s];this.variableBuilder.updateFromDatum(o),this.updateSide(-.5),this.updatePos(0),this.variableBuilder.pushAll();const a=1;for(let c=0;c<=a;c++)this.updatePos(c/a),this.updateSide(-.5),this.variableBuilder.pushAll(),this.updateSide(.5),this.variableBuilder.pushAll();this.variableBuilder.pushAll(),this.addToXIndex(o)}this.registerBatch(e)}}class H5 extends Ro{constructor({encoders:e,attributes:t,numItems:r=void 0}){super({encoders:e,attributes:t,numVertices:r}),this.variableBuilder.configure()}}class V5 extends Ro{constructor({encoders:e,attributes:t,numItems:r=void 0}){super({encoders:e,attributes:t,numVertices:r}),this.variableBuilder.configure()}toArrays(){const e=this.variableBuilder.arrays;for(let t of Object.values(e))t.divisor=1;return super.toArrays()}}class _5 extends Ro{constructor({encoders:e,attributes:t,fontMetrics:r,properties:i,numCharacters:s=void 0}){super({encoders:e,attributes:t,numVertices:s*6}),this.metadata=r,this.metrics=r,this.properties=i;const a=e.text.channelDef;this.numberFormat=!yt(a)&&"format"in a&&a.format?Le(a.format):c=>c,this.updateVertexCoord=this.variableBuilder.createUpdater("vertexCoord",2),this.updateTextureCoord=this.variableBuilder.createUpdater("textureCoord",2),this.updateWidth=this.variableBuilder.createUpdater("width",1),this.variableBuilder.configure()}addBatch(e,t,r=0,i=t.length){const s=this.properties.align||"left",o=this.properties.logoLetters??!1,a=this.metadata.common.base,c=this.metadata.common.scaleH;let u=-5;switch(this.properties.baseline){case"top":u+=this.metrics.capHeight;break;case"middle":u+=this.metrics.capHeight/2;break;case"bottom":u-=this.metrics.descent;break}const l=this.encoders.text,f=[0,0];this.updateVertexCoord(f);const d=[0,0];this.updateTextureCoord(d),this.prepareXIndexer(t,r,i);for(let h=r;h<i;h++){const p=t[h],m=this.numberFormat(l(p)),g=me(m)?m:m===null?"":""+m;if(g.length==0)continue;this.variableBuilder.updateFromDatum(p);const y=o?g.length:this.metrics.measureWidth(g);this.updateWidth(y);let x=s=="right"?-y:s=="center"?-y/2:0;if(!o){const C=this.metrics.getCharByCode(g.charCodeAt(0));x-=(C.width-C.xadvance)/a/2}let A=-.5,w=1,S=1;for(let C=0;C<g.length;C++){const v=this.metrics.getCharByCode(g.charCodeAt(C)),T=o?1:v.xadvance/a;if(v.id==32){x+=T;continue}o?(S=(v.width+co*2)/v.width,x=-S/2,w=(v.height+co*2)/v.height,A=-.5-co/v.height):(w=v.height/a,A=-(v.height+v.yoffset+u)/a,S=v.width/a);const P=v.x,F=v.y;f[0]=x,f[1]=A+w,d[0]=P/c,d[1]=F/c,this.variableBuilder.pushAll(),f[0]=x+S,f[1]=A+w,d[0]=(P+v.width)/c,d[1]=F/c,this.variableBuilder.pushAll(),f[0]=x,f[1]=A,d[0]=P/c,d[1]=(F+v.height)/c,this.variableBuilder.pushAll(),f[0]=x+S,f[1]=A+w,d[0]=(P+v.width)/c,d[1]=F/c,this.variableBuilder.pushAll(),f[0]=x,f[1]=A,d[0]=P/c,d[1]=(F+v.height)/c,this.variableBuilder.pushAll(),f[0]=x+S,f[1]=A,d[0]=(P+v.width)/c,d[1]=(F+v.height)/c,this.variableBuilder.pushAll(),x+=T}this.addToXIndex(p)}this.registerBatch(e)}}const D1=`#define PI 3.141593
+uniform View{mediump vec2 uViewOffset;mediump vec2 uViewScale;mediump vec2 uViewportSize;lowp float uDevicePixelRatio;lowp float uViewOpacity;bool uPickingEnabled;};/***Maps a coordinate on the unit scale to a normalized device coordinate.*(0,0)is at the bottom left corner.*/vec4 unitToNdc(vec2 coord){return vec4((coord*uViewScale+uViewOffset)*2.0-1.0,0.0,1.0);}vec4 unitToNdc(float x,float y){return unitToNdc(vec2(x,y));}vec4 pixelsToNdc(vec2 coord){return unitToNdc(coord/uViewportSize);}vec4 pixelsToNdc(float x,float y){return pixelsToNdc(vec2(x,y));}float linearstep(float edge0,float edge1,float x){return clamp((x-edge0)/(edge1-edge0),0.0,1.0);}bool isEmptyBinarySearchTexture(highp usampler2D s){return textureSize(s,0).x==1&&texelFetch(s,ivec2(0,0),0).r==0u;}bool binarySearchTexture(highp usampler2D s,uint value){int texSize=textureSize(s,0).x;if(texSize==1&&texelFetch(s,ivec2(0,0),0).r==0u){return false;}int left=0;int right=texSize-1;while(left<=right){int mid=left+(right-left)/2;uint midValue=texelFetch(s,ivec2(mid,0),0).r;if(midValue==value){return true;}if(midValue<value){left=mid+1;}else{right=mid-1;}}return false;}/***Calculates a gamma for antialiasing opacity based on the color.*/float getGammaForColor(vec3 rgb){return mix(1.25,0.75,smoothstep(0.0,1.0,dot(rgb,vec3(0.299,0.587,0.114))));}/***Specialized linearstep for doing antialiasing*/float distanceToRatio(float d){return clamp(d*uDevicePixelRatio+0.5,0.0,1.0);}vec4 distanceToColor(float d,vec4 fill,vec4 stroke,vec4 background,float halfStrokeWidth){if(halfStrokeWidth>0.0){float sd=abs(d)-halfStrokeWidth;return mix(stroke,d<=0.0 ? fill : background,distanceToRatio(sd));}else{return mix(background,fill,distanceToRatio(-d));}}`,j5="uniform highp float uZero;vec3 getDiscreteColor(sampler2D s,int index){return texelFetch(s,ivec2(index % textureSize(s,0).x,0),0).rgb;}vec3 getInterpolatedColor(sampler2D s,float unitValue){return texture(s,vec2(unitValue,0.0)).rgb;}float clampToRange(float value,vec2 range){return clamp(value,min(range[0],range[1]),max(range[0],range[1]));}float scaleIdentity(float value){return value;}float scaleIdentity(uint value){return float(value);}float scaleLinear(float value,vec2 domain,vec2 range){float domainSpan=domain[1]-domain[0];float rangeSpan=range[1]-range[0];return(value-domain[0])/domainSpan*rangeSpan+range[0];}float scaleLog(float value,vec2 domain,vec2 range,float base){return scaleLinear(log(value)/log(base),log(domain)/log(base),range);}float symlog(float value,float constant){return sign(value)*log(abs(value/constant)+1.0);}float scaleSymlog(float value,vec2 domain,vec2 range,float constant){return scaleLinear(symlog(value,constant),vec2(symlog(domain[0],constant),symlog(domain[1],constant)),range);}float scalePow(float value,vec2 domain,vec2 range,float exponent){return scaleLinear(pow(abs(value),exponent)*sign(value),pow(abs(domain),vec2(exponent))*sign(domain),range);}float scaleBand(uint value,vec2 domainExtent,vec2 range,float paddingInner,float paddingOuter,float align,float band){float start=range[0];float stop=range[1];float rangeSpan=stop-start;float n=domainExtent[1]-domainExtent[0];paddingInner=int(n)>1 ? paddingInner : 0.0;float step=rangeSpan/max(1.0,n-paddingInner+paddingOuter*2.0);start+=(rangeSpan-step*(n-paddingInner))*align;float bandwidth=step*(1.0-paddingInner);return start+(float(value)-domainExtent[0])*step+bandwidth*band;}const int lowBits=12;const float lowDivisor=pow(2.0,float(lowBits));const uint lowMask=uint(lowDivisor-1.0);vec2 splitUint(uint value){uint valueLo=value&lowMask;uint valueHi=value-valueLo;return vec2(float(valueHi),float(valueLo));}/***High precision variant of scaleBand for index/locus scales*/float scaleBandHp(uint value,vec3 domainExtent,vec2 range,float paddingInner,float paddingOuter,float align,float band){float start=range[0];float stop=range[1];float rangeSpan=stop-start;vec2 domainStart=domainExtent.xy;float n=domainExtent[2];float step=rangeSpan/max(1.0,n-paddingInner+paddingOuter*2.0);start+=(rangeSpan-step*(n-paddingInner))*align;float bandwidth=step*(1.0-paddingInner);vec2 splitValue=splitUint(value);float inf=1.0/uZero;float hi=max(splitValue[0]-domainStart[0],-inf);float lo=max(splitValue[1]-domainStart[1],-inf);return dot(vec4(start,hi,lo,bandwidth),vec4(1.0,step,step,band));}/***High precision variant of scaleBand for index/locus scales for large*domains where 32bit uints are not sufficient to represent the domain.*/float scaleBandHp(uvec2 value,vec3 domainExtent,vec2 range,float paddingInner,float paddingOuter,float align,float band){float start=range[0];float stop=range[1];float rangeSpan=stop-start;vec2 domainStart=domainExtent.xy;float n=domainExtent[2];float step=rangeSpan/max(1.0,n-paddingInner+paddingOuter*2.0);start+=(rangeSpan-step*(n-paddingInner))*align;float bandwidth=step*(1.0-paddingInner);vec2 splitValue=vec2(float(value[0])*lowDivisor,float(value[1]));float inf=1.0/uZero;float hi=max(splitValue[0]-domainStart[0],-inf);float lo=max(splitValue[1]-domainStart[1],-inf);return dot(vec4(start,hi,lo,bandwidth),vec4(1.0,step,step,band));}",Q5=`/***Describes where a sample facet should be shown. Interpolating between the*current and target positions/heights allows for transitioning between facet*configurations.*/struct SampleFacetPosition{float pos;float height;float targetPos;float targetHeight;};/***Trasition fraction[0,1]between the current and target configurations.*/uniform float uTransitionOffset;
 #if !defined(SAMPLE_FACET_UNIFORM) && !defined(SAMPLE_FACET_TEXTURE)
 SampleFacetPosition getSampleFacetPos(){return SampleFacetPosition(0.0,1.0,0.0,1.0);}
 #elif defined(SAMPLE_FACET_UNIFORM)
@@ -427,37 +427,37 @@ SampleFacetPosition getSampleFacetPos(){return SampleFacetPosition(0.0,1.0,0.0,1
 #elif defined(SAMPLE_FACET_TEXTURE)
 uniform sampler2D uSampleFacetTexture;SampleFacetPosition getSampleFacetPos(){vec4 texel=texelFetch(uSampleFacetTexture,ivec2(int(attr_facetIndex),0),0);return SampleFacetPosition(1.0-texel.r-texel.g,texel.g,1.0-texel.r-texel.g,texel.g);}
 #endif
-bool isFacetedSamples(SampleFacetPosition facetPos){return facetPos!=SampleFacetPosition(0.0,1.0,0.0,1.0);}bool isFacetedSamples(){return isFacetedSamples(getSampleFacetPos());}bool isInTransit(){return uTransitionOffset>0.0;}float getTransitionFraction(float xPos){return smoothstep(0.0,0.7+uTransitionOffset,(xPos-uTransitionOffset)*2.0);}vec2 applySampleFacet(vec2 pos){SampleFacetPosition facetPos=getSampleFacetPos();if(!isFacetedSamples(facetPos)){return pos;}else if(isInTransit()){vec2 interpolated=mix(vec2(facetPos.pos,facetPos.height),vec2(facetPos.targetPos,facetPos.targetHeight),getTransitionFraction(pos.x));return vec2(pos.x,interpolated[0]+pos.y*interpolated[1]);}else{return vec2(pos.x,facetPos.pos+pos.y*facetPos.height);}}float getSampleFacetHeight(vec2 pos){SampleFacetPosition facetPos=getSampleFacetPos();if(!isFacetedSamples(facetPos)){return 1.0;}else if(isInTransit()){return mix(facetPos.height,facetPos.targetHeight,getTransitionFraction(pos.x));}else{return facetPos.height;}}`,dD=`/**Based on concepts presented at:*https:*https:*/out highp vec4 vPickingColor;/***Passes the unique id to the fragment shader as a color if picking is enabled.*Returns true if picking is enabled.*/bool setupPicking(){if(uPickingEnabled){
+bool isFacetedSamples(SampleFacetPosition facetPos){return facetPos!=SampleFacetPosition(0.0,1.0,0.0,1.0);}bool isFacetedSamples(){return isFacetedSamples(getSampleFacetPos());}bool isInTransit(){return uTransitionOffset>0.0;}float getTransitionFraction(float xPos){return smoothstep(0.0,0.7+uTransitionOffset,(xPos-uTransitionOffset)*2.0);}vec2 applySampleFacet(vec2 pos){SampleFacetPosition facetPos=getSampleFacetPos();if(!isFacetedSamples(facetPos)){return pos;}else if(isInTransit()){vec2 interpolated=mix(vec2(facetPos.pos,facetPos.height),vec2(facetPos.targetPos,facetPos.targetHeight),getTransitionFraction(pos.x));return vec2(pos.x,interpolated[0]+pos.y*interpolated[1]);}else{return vec2(pos.x,facetPos.pos+pos.y*facetPos.height);}}float getSampleFacetHeight(vec2 pos){SampleFacetPosition facetPos=getSampleFacetPos();if(!isFacetedSamples(facetPos)){return 1.0;}else if(isInTransit()){return mix(facetPos.height,facetPos.targetHeight,getTransitionFraction(pos.x));}else{return facetPos.height;}}`,W5=`/**Based on concepts presented at:*https:*https:*/out highp vec4 vPickingColor;/***Passes the unique id to the fragment shader as a color if picking is enabled.*Returns true if picking is enabled.*/bool setupPicking(){if(uPickingEnabled){
 #ifdef uniqueId_DEFINED
 uint id=attr_uniqueId;vPickingColor=vec4(ivec4(id>>0,id>>8,id>>16,id>>24)&0xFF)/float(0xFF);
 #else
 vPickingColor=vec4(1.0);
 #endif
-return true;}return false;}`,pD="in highp vec4 vPickingColor;",Nl=Symbol("cacheMap");function zl(t,e,n){let r=va(t).get(e);return r===void 0&&(r=n(e),va(t).set(e,r)),r}function gD(t,e){va(t).delete(e)}function Ul(t,e){const n=va(t);for(const r of n.keys())r.startsWith(e)&&n.delete(r);va(t).delete(e)}function tb(t){t[Nl]=new Map}function va(t){return t[Nl]||tb(t),t[Nl]}function nb(...t){const e={get(n,r,o){for(const i of t){const a=i()[r];if(a!==void 0)return a}},has(n,r,o){for(const i of t){const s=i();if(r in s)return!0}return!1}};return new Proxy({},e)}function mD(t){return rt(t)||Ht(t)||ps(t)}class Pr extends Error{constructor(e,n){super(e),this.name="ViewError",this.view=n}}const yD="SAMPLE_FACET_UNIFORM",rb="SAMPLE_FACET_TEXTURE",ib="uSelectionTexture_";class Aa{constructor(e){he(this,Tn,[]);this.unitView=e,this.encoders=void 0,this.bufferInfo=void 0,this.bytesPerElement=new Map,this.programInfo=void 0,this.vertexArrayInfo=void 0,this.viewUniformInfo=void 0,this.markUniformInfo=void 0,this.markUniformsAltered=!0,this.selectionTextureOps=[],this.rangeMap=new bD,this.defaultProperties={get clip(){return["x","y"].map(n=>e.getScaleResolution(n)).some(n=>(n==null?void 0:n.isZoomable())??!1)},xOffset:0,yOffset:0,minBufferSize:0},this.properties=nb(typeof this.unitView.spec.mark=="object"?()=>this.unitView.spec.mark:()=>({}),()=>this.defaultProperties)}augmentDefaultProperties(e){Object.defineProperties(this.defaultProperties,Object.getOwnPropertyDescriptors(e))}get opaque(){return!1}get defaultHitTestMode(){return"intersects"}getAttributes(){throw new Error("Not implemented!")}getSupportedChannels(){return["sample","facetIndex","x","y","color","opacity","search","uniqueId"]}getDefaultEncoding(){const e={sample:void 0,uniqueId:void 0};return this.isPickingParticipant()&&(e.uniqueId={field:sn}),e}fixEncoding(e){return e}setupExprRefsNeedingGraphicsUpdate(e){const n=this.getSupportedChannels(),r={};for(const i of e){const s=this.properties[i];if(s&&Ot(s)){const a=this.unitView.paramMediator.createExpression(s.expr);a.addListener(()=>{this.updateGraphicsData(),this.unitView.context.animator.requestRender()}),n.includes(i)||Object.defineProperty(r,i,{get(){return a()}})}}const o=this.properties;this.properties=nb(()=>r,()=>o)}get encoding(){return zl(this,"encoding",()=>{var s;const e=this.getDefaultEncoding(),n=this.unitView.getEncoding(),r=a=>{const c=this.properties[a];return mD(c)||Ot(c)?{value:c}:void 0},o=Object.fromEntries(this.getSupportedChannels().map(a=>[a,r(a)]).filter(a=>ln(a[1]))),i=this.fixEncoding({...e,...o,...n});for(const a of Object.keys(i))this.getSupportedChannels().includes(a)||delete i[a];return i.x&&((s=i.x).buildIndex??(s.buildIndex=!0)),i})}getContext(){return this.unitView.context}getType(){return this.unitView.getMarkType()}initializeData(){}initializeEncoders(){this.encoders=G5(this.unitView,this.encoding)}async initializeGraphics(){}updateGraphicsData(){}getSampleFacetMode(){if(this.encoders.facetIndex)return rb;if(this.unitView.getLayoutAncestors().find(e=>"samples"in e.spec))return yD}createAndLinkShaders(e,n,r=[]){const o=this.getAttributes(),i=this.encoders,s=this.getSampleFacetMode();s&&r.push(`#define ${s}`);const a="// view: "+this.unitView.getPathString();let c=[];const l=new Set,u=Jy(i),f=[],d=Object.values(i).flatMap(I=>I.accessors).map(I=>I.predicate).filter(I=>I.param),h=new Map;for(const I of d){const _=I.param,B=this.unitView.paramMediator,N=B.findValue(_);if(!N)throw new Error(`Cannot infer selection type as the parameter "${_}" has no value. Please ensure that the parameter is properly defined!`);const F=xo("uniqueId");if(u1(N)){if(!h.has(_)){h.set(_,"single");const M=Ol+ra(_);f.push("    // Selection parameter"),f.push(`    uniform highp uint ${M};`),j(this,Tn).push(()=>{this.registerMarkUniformValue(M,{expr:_},C=>C.uniqueId??0)}),c.push(`bool ${ba}${_}(bool empty) {
-    return ${Ol}${_} == ${F} || (empty && ${Ol}${_} == 0u);
-}`)}}else if(ih(N)){if(!h.has(_)){h.set(_,"multi");const M=ib+ra(_);c.push(`// Selection texture
-uniform highp usampler2D ${M};`);const C=this.getContext().glHelper,Y=C.selectionTextures;this.selectionTextureOps.push(()=>{const se=B.getValue(_),ae=Y.get(se);if(!ae)throw new Error(`Bug: no selection texture found for "${_}"!`);li(this.programInfo,{[M]:ae})});const Q=ib+_;c.push(`bool ${ba}${_}(bool empty) {
-   return binarySearchTexture(${Q}, ${F}) || (empty && isEmptyBinarySearchTexture(${Q}));
-}`),C.createSelectionTexture(N);const oe=B.createExpression(_);oe.addListener(()=>{const se=oe(null);C.createSelectionTexture(se),this.getContext().animator.requestRender()})}}else if(l1(N)&&!h.has(_)){h.set(_,"interval");const M=[],C=[];for(const Y of Object.keys(N.intervals)){if(!["x","y"].includes(Y))continue;const Q=Ol+ra(_)+`_${Y}`,{attributeType:oe}=wo(this.unitView.getScaleResolution(Y).scale,Y);f.push("    // Selection parameter"),f.push(`    uniform highp ${oe}[2] ${Q};`),j(this,Tn).push(()=>{this.registerMarkUniformValue(Q,{expr:_},Ce=>Ce.intervals[Y]??[1,0])});const se=Ce=>{for(const[me,Ee]of u.entries())if(me[1]&&Ee.includes(Ce))return xo(Ee);return xo(Ce)},ae=se(Y),ce=Q+"[0]",ye=Q+"[1]",de=ch(Y);if(this.encoding[de]){const Ce=se(de),me=this.defaultHitTestMode;if(me=="endpoints")M.push(`((${ce} <= ${ae} && ${ae} <= ${ye}) || (${ce} <= ${Ce} && ${Ce} <= ${ye}))`);else if(me=="encloses")M.push(`(${ce} <= ${ae} && ${Ce} <= ${ye})`);else if(me=="intersects")M.push(`(${ce} <= ${Ce} && ${ae} <= ${ye})`);else throw new Pr(`Unsupported hit test mode "${me}" for interval selection!`,this.unitView)}else M.push(`(${ce} <= ${ae} && ${ae} <= ${ye})`);C.push(`${ce} > ${ye}`)}c.push(`bool ${ba}${_}(bool empty) {
-    return ${M.join(" && ")} || (empty && (${C.join(" || ")}));
-}`)}}const p=(I,_,B,N)=>{const F=_.channelDef;if(ln(F))if(Ot(F.value)){const{uniformName:M,uniformGlsl:C,accessorGlsl:Y,adjuster:Q}=QT(I,B);c.push(Y),f.push(C),j(this,Tn).push(()=>{this.registerMarkUniformValue(M,F.value,Q)})}else c.push(YT(I,B,F.value).accessorGlsl);else if(ia(F)){const{uniformName:M,uniformGlsl:C,accessorGlsl:Y}=ZT(I,N,B);f.push(C),c.push(Y);const{largeHp:Q,discrete:oe}=wo(N,I),se=oe&&"domain"in N?ae=>N.domain().indexOf(ae):Q?Ky:ae=>+ae;j(this,Tn).push(()=>{this.registerMarkUniformValue(M,F.datum,se)})}else if(Ir(F)){const M=u.get([F.field,!0]),{attributeGlsl:C,accessorGlsl:Y}=qy(I,N,B,M!=null&&M.includes(I)?M:void 0);l.add(C),c.push(Y)}else if(oa(F)){const{attributeGlsl:M,accessorGlsl:C}=qy(I,N,B);l.add(M),c.push(C)}else throw new Pr(`Unsupported channel definition: ${JSON.stringify(F)}`,this.unitView)};for(const[I,_]of Object.entries(i)){if(!o.includes(I))continue;const{channelDef:B,accessors:N,scale:F}=_;for(let M=0;M<N.length;M++)p(I,N[M],M,F);if(F){const M=m1(B),C=M&&M.resolutionChannel||I,Y=xl(C)?this.unitView.getScaleResolution(C):null,{glsl:Q,domainUniform:oe,domainUniformName:se,rangeUniform:ae,rangeUniformName:ce}=XT(I,F,B);c.push(Q),f.push(oe),f.push(ae),ae&&j(this,Tn).push(()=>{const ye=this.createMarkUniformSetter(ce),de=()=>ye($y(F,I));Y.addEventListener("range",de),de()}),oe&&j(this,Tn).push(()=>{const ye=this.createMarkUniformSetter(se),de=()=>{const Ce=Mr(F.type)?[0,F.domain().length]:F.domain();ye(Xy(F.type)?nD(Ce):Ce)};Y.addEventListener("domain",de),de()})}c.push(KT(I,N))}const y=[...h.keys()].map(I=>`${ba}${I}(false)`);c.push(`bool isPointSelected() {
-`+(this.encoders.uniqueId&&y.length>0?`    return ${y.join(" || ")};`:"    return false;")+`
-}`);const v=`precision highp float;
-precision highp int;`,b=I=>I.replace("#pragma markUniforms",f.join(`
-`));r=r.map(b),e=b(e),n=b(n);const A=[v,a,...r,eb,fD,[...l].join(`
-`),...c,hD,dD,e],S=[v,a,...r,eb,pD,n],E=this.gl;this.programStatus=MT(E,this.glHelper.compileShader(E.VERTEX_SHADER,A),this.glHelper.compileShader(E.FRAGMENT_SHADER,S))}finalizeGraphicsInitialization(){const e=this.programStatus.getProgramErrors();if(e){e.detail&&console.warn(e.detail);const n=new Error("Cannot create shader program: "+e.message);throw n.view=this.unitView,n}this.programInfo=P6(this.gl,this.programStatus.program),delete this.programStatus,this.viewUniformInfo=vm(this.gl,this.programInfo,"View"),this.markUniformInfo=vm(this.gl,this.programInfo,"Mark"),this.gl.useProgram(this.programInfo.program),li(this.programInfo,{uSampleFacet:[0,1,0,1],uTransitionOffset:0,uZero:0});for(const n of j(this,Tn))n();Ae(this,Tn,void 0)}createMarkUniformSetter(e){const n=this.markUniformInfo.setters[e];if(!n)throw new Error(`Uniform "${e}" not found int the Mark block!`);return r=>{n(r),this.markUniformsAltered=!0,this.unitView.context.animator.requestRender()}}registerMarkUniformValue(e,n,r=o=>o){const o=this.createMarkUniformSetter(e),i=s=>{if(s==null)throw new Error(`Trying to set null/undefined value for uniform: ${e}${Ot(n)?`Expr: ${n.expr}`:""}`);o(s)};if(Ot(n)){const s=this.unitView.paramMediator.createExpression(n.expr),a=()=>i(r(s(null)));s.addListener(a),a()}else i(r(n))}deleteGraphicsData(){const e=this.gl;if(this.vertexArrayInfo&&(this.gl.bindVertexArray(null),e.deleteVertexArray(this.vertexArrayInfo.vertexArrayObject),this.vertexArrayInfo=void 0),this.bufferInfo){for(let n=0;n<8;n++)e.disableVertexAttribArray(n);Object.values(this.bufferInfo.attribs).forEach(n=>this.gl.deleteBuffer(n.buffer)),this.bufferInfo.indices&&this.gl.deleteBuffer(this.bufferInfo.indices),this.bufferInfo=void 0}}updateBufferInfo(e){if(this.gl.bindVertexArray(null),this.bufferInfo&&e.vertexCount<=this.bufferInfo.allocatedVertices)for(const[n,r]of Object.entries(e.arrays))r.data&&QS(this.gl,this.bufferInfo.attribs[n],r.data,0);else{this.deleteGraphicsData(),this.bufferInfo=KS(this.gl,e.arrays,{numElements:e.vertexCount}),this.bufferInfo.allocatedVertices=e.allocatedVertices;for(const[n,r]of Object.entries(e.arrays))this.bytesPerElement.set(n,r.data.BYTES_PER_ELEMENT)}}get glHelper(){return this.getContext().glHelper}get gl(){return this.glHelper.gl}onBeforeSampleAnimation(){}onAfterSampleAnimation(){}isReady(){return this.bufferInfo&&this.programInfo}isPickingParticipant(){if(this.properties.tooltip===null&&!this.unitView.paramMediator.hasPointSelections())return!1;for(const e of this.unitView.getLayoutAncestors())if(!e.isPickingSupported())return!1;return!0}bindOrSetMarkUniformBlock(){this.markUniformsAltered?(Em(this.gl,this.programInfo,this.markUniformInfo),this.markUniformsAltered=!1):Am(this.gl,this.programInfo,this.markUniformInfo)}prepareRender(e){const n=this.glHelper,r=this.gl,o=[];o.push(()=>{this.vertexArrayInfo||(this.vertexArrayInfo=e8(this.gl,this.programInfo,this.bufferInfo)),r.useProgram(this.programInfo.program)});for(const[s,a]of Object.entries(this.encoders)){const c=n.rangeTextures.get(a.scale);c&&o.push(()=>li(this.programInfo,{[Jh+s]:c}))}o.push(...this.selectionTextureOps),this.getSampleFacetMode()==rb&&o.push(()=>{let s;for(const a of this.unitView.getLayoutAncestors())if(s=a.getSampleFacetTexture(),s)break;if(!s)throw new Error("No facet texture available. This is bug.");li(this.programInfo,{uSampleFacetTexture:s})});const i=(e.picking??!1)&&this.isPickingParticipant();return o.push(()=>Qs(this.viewUniformInfo,{uViewOpacity:this.unitView.getEffectiveOpacity(),uPickingEnabled:i})),this.opaque||e.picking?o.push(()=>r.disable(r.BLEND)):o.push(()=>r.enable(r.BLEND)),o}prepareSampleFacetRendering(e){const n=e.sampleFacetRenderingOptions,r=this.programInfo.uniformSetters.uSampleFacet;if(n&&r){const o=n.locSize?n.locSize.location:0,i=n.locSize?n.locSize.size:1;if(o>1||o+i<0)return!1;const s=n.targetLocSize?n.targetLocSize.location:o,a=n.targetLocSize?n.targetLocSize.size:i;this.gl.uniform4f(r.location,o,i,s,a)}return!0}render(e){}createRenderCallback(e,n){var f;if(!this.bufferInfo)return()=>{};const r=this;let o;const i=(f=this.unitView.getScaleResolution("x"))==null?void 0:f.scale,s=i&&St(i.type),a=["index","locus"].includes(i==null?void 0:i.type)?-1:0,c=[0,0];o=d=>{if(s&&d.xIndex){const h=i.domain(),p=d.xIndex(h[0]+a,h[1],c),y=p[0],v=p[1]-y;v>0&&e(y,v)}else e(d.offset,d.count)};const l=this.rangeMap.get(void 0).count==0?n.facetId:void 0,u=this.rangeMap.get(l);return n.sampleFacetRenderingOptions?function(){u.count&&r.prepareSampleFacetRendering(n)&&o(u)}:function(){u.count&&o(u)}}setViewport(e,n,r,o){r=r.flatten();const i=this.gl,s=this.properties,a=.5,c=(s.xOffset??0)+a,l=(s.yOffset??0)+a;let u,f=r;if(s.clip!=="never"&&(s.clip||o)){let d=0,h=0,p;if(o){if(f=r.intersect(o).flatten(),!f.isDefined())return!1;p=[r.width/f.width,r.height/f.height],h=Math.max(0,r.y2-o.y2),d=Math.min(0,r.x-o.x)}else p=[1,1];const y=[f.x,e.height-f.y2,f.width,f.height].map(S=>S*n),v=y.map(S=>Math.floor(S)),b=y[0]-v[0],A=y[1]-v[1];i.viewport(...v),i.scissor(...v),i.enable(i.SCISSOR_TEST),u={uViewOffset:[(c+d+b/n)/f.width,-(l+h-A/n)/f.height],uViewScale:p}}else{if(!r.isDefined())return!1;i.viewport(0,0,e.width*n,e.height*n),i.disable(i.SCISSOR_TEST),u={uViewOffset:[(r.x+c)/e.width,(e.height-r.y-l-r.height)/e.height],uViewScale:[r.width/e.width,r.height/e.height]}}return Qs(this.viewUniformInfo,{...u,uViewportSize:[r.width,r.height],uDevicePixelRatio:n}),Em(this.gl,this.programInfo,this.viewUniformInfo),!0}findDatumAt(e,n){}}Tn=new WeakMap;class bD extends Yn{constructor(){super([],JSON.stringify)}get(e){let n=super.get(e);return n===void 0&&(n={offset:0,count:0,xIndex:void 0},super.set(e,n)),n}migrateEntries(e){for(const[n,r]of this.entries())e.has(n)||(r.offset=0,r.count=0,r.xIndex=void 0);for(const[n,r]of e.entries())Object.assign(this.get(n),r)}}function ed(t,e){const n=ch(e);let r=t[e]&&{...t[e]},o=t[n]&&{...t[n]};if(!(ln(r)||ln(o))){if(r){if(!$t(t[e]))return;if(o){if(r.type!="quantitative"){const i=(1-(r.band||1))/2;r.band=i,o.band=-i}}else if(r.type=="quantitative")o={datum:0,contributesToScaleDomain:!1};else{o={...r};const i=(1-(r.band??1))/2;r.band=0+i,o.band=1-i}}else r={value:0},o={value:1};t[e]=r,t[n]=o}}function Gl(t,e){const n=m1(t);n&&(n.resolutionChannel=e)}function ob(t,e){t.stroke||(e?t.stroke={value:null}:(t.stroke=structuredClone(t.color),Gl(t.stroke,"color"))),ln(t.stroke)&&t.stroke.value===null&&(t.strokeWidth={value:0}),t.strokeOpacity||(t.strokeOpacity=structuredClone(t.opacity),Gl(t.strokeOpacity,"opacity"))}function sb(t,e){ln(t.fill)&&t.fill.value===null?t.fillOpacity={value:0}:t.fill||(t.fill=structuredClone(t.color),Gl(t.fill,"color"),!e&&!t.fillOpacity&&(t.fillOpacity={value:0})),t.fillOpacity||(e?(t.fillOpacity=structuredClone(t.opacity),Gl(t.fillOpacity,"opacity")):t.fillOpacity={value:0})}const wD=["none","diagonal","antiDiagonal","cross","vertical","horizontal","grid","dots","rings","ringsLarge"];class xD extends Aa{constructor(n){super(n);he(this,Hr);this.augmentDefaultProperties({x2:void 0,y2:void 0,filled:!0,color:"#4c78a8",opacity:1,strokeWidth:3,cornerRadius:0,minWidth:.5,minHeight:.5,minOpacity:1})}getAttributes(){return["uniqueId","facetIndex","x","x2","y","y2","fill","stroke","fillOpacity","strokeOpacity","strokeWidth"]}getSupportedChannels(){return[...super.getSupportedChannels(),"x2","y2","fill","stroke","fillOpacity","strokeOpacity","strokeWidth"]}get opaque(){return zl(this,"opaque",()=>!pe(this,Hr,L0).call(this)&&!pe(this,Hr,O0).call(this)&&!this.properties.shadowOpacity&&ln(this.encoding.fillOpacity)&&this.encoding.fillOpacity.value==1&&this.properties.minOpacity==1)&&this.unitView.getEffectiveOpacity()==1}fixEncoding(n){return ed(n,"x"),ed(n,"y"),ob(n,this.properties.filled),sb(n,this.properties.filled),delete n.color,delete n.opacity,n}onBeforeSampleAnimation(){}onAfterSampleAnimation(){}async initializeGraphics(){await super.initializeGraphics();const n=[];pe(this,Hr,L0).call(this)&&n.push("ROUNDED_CORNERS"),pe(this,Hr,O0).call(this)&&n.push("STROKED"),this.properties.shadowOpacity&&n.push("SHADOW"),this.createAndLinkShaders(o8,s8,[a8,...n.map(r=>"#define "+r)])}finalizeGraphicsInitialization(){super.finalizeGraphicsInitialization(),this.gl.useProgram(this.programInfo.program);const n=this.properties;this.registerMarkUniformValue("uMinWidth",n.minWidth),this.registerMarkUniformValue("uMinHeight",n.minHeight),this.registerMarkUniformValue("uMinOpacity",n.minOpacity),this.registerMarkUniformValue("uCornerRadiusTopRight",n.cornerRadiusTopRight??n.cornerRadius??0),this.registerMarkUniformValue("uCornerRadiusBottomRight",n.cornerRadiusBottomRight??n.cornerRadius??0),this.registerMarkUniformValue("uCornerRadiusTopLeft",n.cornerRadiusTopLeft??n.cornerRadius??0),this.registerMarkUniformValue("uCornerRadiusBottomLeft",n.cornerRadiusBottomLeft??n.cornerRadius??0),this.registerMarkUniformValue("uHatchPattern",n.hatch,r=>Math.max(0,wD.indexOf(r??"none"))),this.registerMarkUniformValue("uShadowBlur",n.shadowBlur??0),this.registerMarkUniformValue("uShadowOpacity",n.shadowOpacity??0),this.registerMarkUniformValue("uShadowOffsetX",n.shadowOffsetX??0),this.registerMarkUniformValue("uShadowOffsetY",n.shadowOffsetY??0),this.registerMarkUniformValue("uShadowColor",n.shadowColor??"black",Kh)}updateGraphicsData(){const n=this.unitView.getCollector();if(!n){console.debug("No collector");return}const r=n.getItemCount(),o=new sD({encoders:this.encoders,attributes:this.getAttributes(),numItems:r});o.addBatches(n.facetBatches);const i=o.toArrays();this.rangeMap.migrateEntries(i.rangeMap),this.updateBufferInfo(i)}prepareRender(n){const r=super.prepareRender(n);return r.push(()=>this.bindOrSetMarkUniformBlock()),r.push(()=>ui(this.gl,this.programInfo,this.vertexArrayInfo)),r}render(n){const r=this.gl;return this.createRenderCallback((o,i)=>{al(r,this.vertexArrayInfo,r.TRIANGLE_STRIP,i,o)},n)}findDatumAt(n,r){n=Ft(n);const o=this.unitView.getCollector().facetBatches.get(n);if(!o)return;const i=this.encoders,s=i.x.scale.type;if(Mr(s)){const a=i.x.dataAccessor;return o.find(c=>r==a(c))}else{const a=i.x.dataAccessor,c=i.x2.dataAccessor;return o.find(l=>r>=a(l)&&r<c(l))}}}Hr=new WeakSet,L0=function(){const n=this.properties;return n.cornerRadius||n.cornerRadiusBottomLeft||n.cornerRadiusBottomRight||n.cornerRadiusTopLeft||n.cornerRadiusTopRight},O0=function(){const n=this.encoding.strokeWidth;return!(ln(n)&&!n.value)||"condition"in n};const vD=`flat out float vRadius;flat out float vRadiusWithPadding;flat out lowp vec4 vFillColor;flat out lowp vec4 vStrokeColor;flat out lowp float vShape;flat out lowp float vHalfStrokeWidth;flat out mat2 vRotationMatrix;const float CIRCLE=0.0;const float SQUARE=1.0;const float CROSS=2.0;const float DIAMOND=3.0;const float TRIANGLE_UP=4.0;const float TRIANGLE_RIGHT=5.0;const float TRIANGLE_DOWN=6.0;const float TRIANGLE_LEFT=7.0;const float TICK_UP=8.0;const float TICK_RIGHT=9.0;const float TICK_DOWN=10.0;const float TICK_LEFT=11.0;float computeSemanticThresholdFactor(){return getScaled_semanticScore()>=uSemanticThreshold ? 1.0 : 0.0;}vec2 getDxDy(){
+return true;}return false;}`,q5="in highp vec4 vPickingColor;",Kc=Symbol("cacheMap");function Jc(n,e,t){let r=Oo(n).get(e);return r===void 0&&(r=t(e),Oo(n).set(e,r)),r}function nh(n,e){Oo(n).delete(e)}function $c(n,e){const t=Oo(n);for(const r of t.keys())r.startsWith(e)&&t.delete(r);Oo(n).delete(e)}function I1(n){n[Kc]=new Map}function Oo(n){return n[Kc]||I1(n),n[Kc]}function T1(...n){const e={get(t,r,i){for(const s of n){const a=s()[r];if(a!==void 0)return a}},has(t,r,i){for(const s of n){const o=s();if(r in o)return!0}return!1}};return new Proxy({},e)}function Y5(n){return me(n)||Ze(n)||Is(n)}class Qn extends Error{constructor(e,t){super(e),this.name="ViewError",this.view=t}}const X5="SAMPLE_FACET_UNIFORM",B1="SAMPLE_FACET_TEXTURE",k1="uSelectionTexture_";class No{constructor(e){R(this,Pt,[]);R(this,ns,[]);this.unitView=e,this.encoders=void 0,this.bufferInfo=void 0,this.bytesPerElement=new Map,this.programInfo=void 0,this.vertexArrayInfo=void 0,this.viewUniformInfo=void 0,this.markUniformInfo=void 0,this.markUniformsAltered=!0,this.selectionTextureOps=[],this.rangeMap=new Z5,this.defaultProperties={get clip(){return["x","y"].map(t=>e.getScaleResolution(t)).some(t=>(t==null?void 0:t.isZoomable())??!1)},xOffset:0,yOffset:0,minBufferSize:0},this.properties=T1(typeof this.unitView.spec.mark=="object"?()=>this.unitView.spec.mark:()=>({}),()=>this.defaultProperties)}augmentDefaultProperties(e){Object.defineProperties(this.defaultProperties,Object.getOwnPropertyDescriptors(e))}get opaque(){return!1}get defaultHitTestMode(){return"intersects"}getAttributes(){throw new Error("Not implemented!")}getSupportedChannels(){return["sample","facetIndex","x","y","color","opacity","search","uniqueId"]}getDefaultEncoding(){const e={sample:void 0,uniqueId:void 0};return this.isPickingParticipant()&&(e.uniqueId={field:pt}),e}fixEncoding(e){return e}setupExprRefsNeedingGraphicsUpdate(e){const t=this.getSupportedChannels(),r={};for(const s of e){const o=this.properties[s];if(o&&Qe(o)){const a=this.unitView.paramMediator.createExpression(o.expr);a.addListener(()=>{this.updateGraphicsData(),this.unitView.context.animator.requestRender()}),t.includes(s)||Object.defineProperty(r,s,{get(){return a()}})}}const i=this.properties;this.properties=T1(()=>r,()=>i)}get encoding(){return Jc(this,"encoding",()=>{var o;const e=this.getDefaultEncoding(),t=this.unitView.getEncoding(),r=a=>{const c=this.properties[a];return Y5(c)||Qe(c)?{value:c}:void 0},i=Object.fromEntries(this.getSupportedChannels().map(a=>[a,r(a)]).filter(a=>yt(a[1]))),s=this.fixEncoding({...e,...i,...t});for(const a of Object.keys(s))this.getSupportedChannels().includes(a)||delete s[a];return s.x&&((o=s.x).buildIndex??(o.buildIndex=!0)),s})}getContext(){return this.unitView.context}getType(){return this.unitView.getMarkType()}initializeData(){}initializeEncoders(){this.encoders=A8(this.unitView,this.encoding)}async initializeGraphics(){}updateGraphicsData(){}getSampleFacetMode(){if(this.encoders.facetIndex)return B1;if(this.unitView.getLayoutAncestors().find(e=>"samples"in e.spec))return X5}createAndLinkShaders(e,t,r=[]){const i=this.getAttributes(),s=this.encoders,o=this.getSampleFacetMode();o&&r.push(`#define ${o}`);const a="// view: "+this.unitView.getPathString();let c=[];const u=new Set,l=E1(s),f=[],d=Object.values(s).flatMap(S=>S.accessors).map(S=>S.predicate).filter(S=>S.param),h=new Map;for(const S of d){const C=S.param,v=this.unitView.paramMediator,T=v.findValue(C);if(!T)throw new Error(`Cannot infer selection type as the parameter "${C}" has no value. Please ensure that the parameter is properly defined!`);const P=Pi("uniqueId");if(Nm(T)){if(!h.has(C)){h.set(C,"single");const F=Zc+yo(C);f.push("    // Selection parameter"),f.push(`    uniform highp uint ${F};`),E(this,Pt).push(()=>{this.registerMarkUniformValue(F,{expr:C},k=>k.uniqueId??0)}),c.push(`bool ${Po}${C}(bool empty) {
+    return ${Zc}${C} == ${P} || (empty && ${Zc}${C} == 0u);
+}`)}}else if(of(T)){if(!h.has(C)){h.set(C,"multi");const F=k1+yo(C);c.push(`// Selection texture
+uniform highp usampler2D ${F};`);const k=this.getContext().glHelper,L=k.selectionTextures;this.selectionTextureOps.push(()=>{const K=v.getValue(C),_=L.get(K);if(!_)throw new Error(`Bug: no selection texture found for "${C}"!`);Ar(this.programInfo,{[F]:_})});const U=k1+C;c.push(`bool ${Po}${C}(bool empty) {
+   return binarySearchTexture(${U}, ${P}) || (empty && isEmptyBinarySearchTexture(${U}));
+}`),k.createSelectionTexture(T);const j=v.createExpression(C);j.addListener(()=>{const K=j(null);k.createSelectionTexture(K),this.getContext().animator.requestRender()})}}else if(Om(T)&&!h.has(C)){h.set(C,"interval");const F=[],k=[];for(const L of Object.keys(T.intervals)){if(!["x","y"].includes(L))continue;const U=Zc+yo(C)+`_${L}`,{attributeType:j}=Fi(this.unitView.getScaleResolution(L).scale,L);f.push("    // Selection parameter"),f.push(`    uniform highp ${j}[2] ${U};`),E(this,Pt).push(()=>{this.registerMarkUniformValue(U,{expr:C},Ne=>Ne.intervals[L]??[1,0])});const K=Ne=>{for(const[ve,Kt]of l.entries())if(ve[1]&&Kt.includes(Ne))return Pi(Kt);return Pi(Ne)},_=K(L),te=U+"[0]",ce=U+"[1]",ie=lf(L);if(this.encoding[ie]){const Ne=K(ie),ve=this.defaultHitTestMode;if(ve=="endpoints")F.push(`((${te} <= ${_} && ${_} <= ${ce}) || (${te} <= ${Ne} && ${Ne} <= ${ce}))`);else if(ve=="encloses")F.push(`(${te} <= ${_} && ${Ne} <= ${ce})`);else if(ve=="intersects")F.push(`(${te} <= ${Ne} && ${_} <= ${ce})`);else throw new Qn(`Unsupported hit test mode "${ve}" for interval selection!`,this.unitView)}else F.push(`(${te} <= ${_} && ${_} <= ${ce})`);k.push(`${te} > ${ce}`)}c.push(`bool ${Po}${C}(bool empty) {
+    return ${F.join(" && ")} || (empty && (${k.join(" || ")}));
+}`)}}const p=(S,C,v,T)=>{const P=C.channelDef;if(yt(P))if(Qe(P.value)){const{uniformName:F,uniformGlsl:k,accessorGlsl:L,adjuster:U}=I5(S,v);c.push(L),f.push(k),E(this,Pt).push(()=>{this.registerMarkUniformValue(F,P.value,U)})}else c.push(D5(S,v,P.value).accessorGlsl);else if(bo(P)){const{uniformName:F,uniformGlsl:k,accessorGlsl:L}=T5(S,T,v);f.push(k),c.push(L);const{largeHp:U,discrete:j}=Fi(T,S),K=j&&"domain"in T?_=>T.domain().indexOf(_):U?S1:_=>+_;E(this,Pt).push(()=>{this.registerMarkUniformValue(F,P.datum,K)})}else if(Nn(P)){const F=l.get([P.field,!0]),{attributeGlsl:k,accessorGlsl:L}=y1(S,T,v,F!=null&&F.includes(S)?F:void 0);u.add(k),c.push(L)}else if(xo(P)){const{attributeGlsl:F,accessorGlsl:k}=y1(S,T,v);u.add(F),c.push(k)}else throw new Qn(`Unsupported channel definition: ${JSON.stringify(P)}`,this.unitView)};for(const[S,C]of Object.entries(s)){if(!i.includes(S))continue;const{channelDef:v,accessors:T,scale:P}=C;for(let F=0;F<T.length;F++)p(S,T[F],F,P);if(P){const F=Vm(v),k=F&&F.resolutionChannel||S,L=Mc(k)?this.unitView.getScaleResolution(k):null,{glsl:U,domainUniform:j,domainUniformName:K,rangeUniform:_,rangeUniformName:te}=B5(S,P,v);c.push(U),f.push(j),f.push(_),_&&E(this,Pt).push(()=>{const ce=this.createMarkUniformSetter(te),ie=()=>ce(C1(P,S));L.addEventListener("range",ie),ie()}),j&&E(this,Pt).push(()=>{const ce=this.createMarkUniformSetter(K),ie=()=>{const Ne=jn(P.type)?[0,P.domain().length]:P.domain();ce(v1(P.type)?O5(Ne):Ne)};L.addEventListener("domain",ie),ie()})}c.push(k5(S,T))}const m=[...h.keys()].map(S=>`${Po}${S}(false)`);c.push(`bool isPointSelected() {
+`+(this.encoders.uniqueId&&m.length>0?`    return ${m.join(" || ")};`:"    return false;")+`
+}`);const g=`precision highp float;
+precision highp int;`,y=S=>S.replace("#pragma markUniforms",f.join(`
+`));r=r.map(y),e=y(e),t=y(t);const x=[g,a,...r,D1,j5,[...u].join(`
+`),...c,Q5,W5,e],A=[g,a,...r,D1,q5,t],w=this.gl;this.programStatus=d5(w,this.glHelper.compileShader(w.VERTEX_SHADER,x),this.glHelper.compileShader(w.FRAGMENT_SHADER,A))}finalizeGraphicsInitialization(){const e=this.programStatus.getProgramErrors();if(e){e.detail&&console.warn(e.detail);const t=new Error("Cannot create shader program: "+e.message);throw t.view=this.unitView,t}this.programInfo=pC(this.gl,this.programStatus.program),delete this.programStatus,this.viewUniformInfo=qp(this.gl,this.programInfo,"View"),this.markUniformInfo=qp(this.gl,this.programInfo,"Mark"),this.gl.useProgram(this.programInfo.program),Ar(this.programInfo,{uSampleFacet:[0,1,0,1],uTransitionOffset:0,uZero:0});for(const t of E(this,Pt))t();G(this,Pt,void 0)}createMarkUniformSetter(e){const t=this.markUniformInfo.setters[e];if(!t)throw new Error(`Uniform "${e}" not found int the Mark block!`);return r=>{t(r),this.markUniformsAltered=!0,this.unitView.context.animator.requestRender()}}registerMarkUniformValue(e,t,r=i=>i){const i=this.createMarkUniformSetter(e),s=o=>{if(o==null)throw new Error(`Trying to set null/undefined value for uniform: ${e}${Qe(t)?`Expr: ${t.expr}`:""}`);i(o)};if(Qe(t)){const o=this.unitView.paramMediator.createExpression(t.expr),a=()=>s(r(o(null)));o.addListener(a),E(this,ns).push({expr:o,listener:a}),a()}else s(r(t))}deleteGraphicsData(){const e=this.glHelper;if(!e){this.vertexArrayInfo=void 0,this.bufferInfo=void 0;return}const t=e.gl;if(this.vertexArrayInfo&&(this.gl.bindVertexArray(null),t.deleteVertexArray(this.vertexArrayInfo.vertexArrayObject),this.vertexArrayInfo=void 0),this.bufferInfo){for(let r=0;r<8;r++)t.disableVertexAttribArray(r);Object.values(this.bufferInfo.attribs).forEach(r=>this.gl.deleteBuffer(r.buffer)),this.bufferInfo.indices&&this.gl.deleteBuffer(this.bufferInfo.indices),this.bufferInfo=void 0}}dispose(){for(const{expr:e,listener:t}of E(this,ns))e.removeListener(t);E(this,ns).length=0,this.deleteGraphicsData()}updateBufferInfo(e){if(this.gl.bindVertexArray(null),this.bufferInfo&&e.vertexCount<=this.bufferInfo.allocatedVertices)for(const[t,r]of Object.entries(e.arrays))r.data&&I3(this.gl,this.bufferInfo.attribs[t],r.data,0);else{this.deleteGraphicsData(),this.bufferInfo=k3(this.gl,e.arrays,{numElements:e.vertexCount}),this.bufferInfo.allocatedVertices=e.allocatedVertices;for(const[t,r]of Object.entries(e.arrays))this.bytesPerElement.set(t,r.data.BYTES_PER_ELEMENT)}}get glHelper(){return this.getContext().glHelper}get gl(){return this.glHelper.gl}onBeforeSampleAnimation(){}onAfterSampleAnimation(){}isReady(){return this.bufferInfo&&this.programInfo}isPickingParticipant(){if(this.properties.tooltip===null&&!this.unitView.paramMediator.hasPointSelections())return!1;for(const e of this.unitView.getLayoutAncestors())if(!e.isPickingSupported())return!1;return!0}bindOrSetMarkUniformBlock(){this.markUniformsAltered?(Xp(this.gl,this.programInfo,this.markUniformInfo),this.markUniformsAltered=!1):Yp(this.gl,this.programInfo,this.markUniformInfo)}prepareRender(e){const t=this.glHelper,r=this.gl,i=[];i.push(()=>{this.vertexArrayInfo||(this.vertexArrayInfo=MC(this.gl,this.programInfo,this.bufferInfo)),r.useProgram(this.programInfo.program)});for(const[o,a]of Object.entries(this.encoders)){const c=t.rangeTextures.get(a.scale);c&&i.push(()=>Ar(this.programInfo,{[eh+o]:c}))}i.push(...this.selectionTextureOps),this.getSampleFacetMode()==B1&&i.push(()=>{let o;for(const a of this.unitView.getLayoutAncestors())if(o=a.getSampleFacetTexture(),o)break;if(!o)throw new Error("No facet texture available. This is bug.");Ar(this.programInfo,{uSampleFacetTexture:o})});const s=(e.picking??!1)&&this.isPickingParticipant();return i.push(()=>ao(this.viewUniformInfo,{uViewOpacity:this.unitView.getEffectiveOpacity(),uPickingEnabled:s})),this.opaque||e.picking?i.push(()=>r.disable(r.BLEND)):i.push(()=>r.enable(r.BLEND)),i}prepareSampleFacetRendering(e){const t=e.sampleFacetRenderingOptions,r=this.programInfo.uniformSetters.uSampleFacet;if(t&&r){const i=t.locSize?t.locSize.location:0,s=t.locSize?t.locSize.size:1;if(i>1||i+s<0)return!1;const o=t.targetLocSize?t.targetLocSize.location:i,a=t.targetLocSize?t.targetLocSize.size:s;this.gl.uniform4f(r.location,i,s,o,a)}return!0}render(e){}createRenderCallback(e,t){var f;if(!this.bufferInfo)return()=>{};const r=this;let i;const s=(f=this.unitView.getScaleResolution("x"))==null?void 0:f.scale,o=s&&Oe(s.type),a=["index","locus"].includes(s==null?void 0:s.type)?-1:0,c=[0,0];i=d=>{if(o&&d.xIndex){const h=s.domain(),p=d.xIndex(h[0]+a,h[1],c),m=p[0],g=p[1]-m;g>0&&e(m,g)}else e(d.offset,d.count)};const u=this.rangeMap.get(void 0).count==0?t.facetId:void 0,l=this.rangeMap.get(u);return t.sampleFacetRenderingOptions?function(){l.count&&r.prepareSampleFacetRendering(t)&&i(l)}:function(){l.count&&i(l)}}setViewport(e,t,r,i){r=r.flatten();const s=this.gl,o=this.properties,a=.5,c=(o.xOffset??0)+a,u=(o.yOffset??0)+a;let l,f=r;if(o.clip!=="never"&&(o.clip||i)){let d=0,h=0,p;if(i){if(f=r.intersect(i).flatten(),!f.isDefined())return!1;p=[r.width/f.width,r.height/f.height],h=Math.max(0,r.y2-i.y2),d=Math.min(0,r.x-i.x)}else p=[1,1];const m=[f.x,e.height-f.y2,f.width,f.height].map(A=>A*t),g=m.map(A=>Math.floor(A)),y=m[0]-g[0],x=m[1]-g[1];s.viewport(...g),s.scissor(...g),s.enable(s.SCISSOR_TEST),l={uViewOffset:[(c+d+y/t)/f.width,-(u+h-x/t)/f.height],uViewScale:p}}else{if(!r.isDefined())return!1;s.viewport(0,0,e.width*t,e.height*t),s.disable(s.SCISSOR_TEST),l={uViewOffset:[(r.x+c)/e.width,(e.height-r.y-u-r.height)/e.height],uViewScale:[r.width/e.width,r.height/e.height]}}return ao(this.viewUniformInfo,{...l,uViewportSize:[r.width,r.height],uDevicePixelRatio:t}),Xp(this.gl,this.programInfo,this.viewUniformInfo),!0}findDatumAt(e,t){}}Pt=new WeakMap,ns=new WeakMap;class Z5 extends tn{constructor(){super([],JSON.stringify)}get(e){let t=super.get(e);return t===void 0&&(t={offset:0,count:0,xIndex:void 0},super.set(e,t)),t}migrateEntries(e){for(const[t,r]of this.entries())e.has(t)||(r.offset=0,r.count=0,r.xIndex=void 0);for(const[t,r]of e.entries())Object.assign(this.get(t),r)}}function rh(n,e){const t=lf(e);let r=n[e]&&{...n[e]},i=n[t]&&{...n[t]};if(!(yt(r)||yt(i))){if(r){if(!lt(n[e]))return;if(i){if(r.type!="quantitative"){const s=(1-(r.band||1))/2;r.band=s,i.band=-s}}else if(r.type=="quantitative")i={datum:0,contributesToScaleDomain:!1};else{i={...r};const s=(1-(r.band??1))/2;r.band=0+s,i.band=1-s}}else r={value:0},i={value:1};n[e]=r,n[t]=i}}function eu(n,e){const t=Vm(n);t&&(t.resolutionChannel=e)}function F1(n,e){n.stroke||(e?n.stroke={value:null}:(n.stroke=structuredClone(n.color),eu(n.stroke,"color"))),yt(n.stroke)&&n.stroke.value===null&&(n.strokeWidth={value:0}),n.strokeOpacity||(n.strokeOpacity=structuredClone(n.opacity),eu(n.strokeOpacity,"opacity"))}function P1(n,e){yt(n.fill)&&n.fill.value===null?n.fillOpacity={value:0}:n.fill||(n.fill=structuredClone(n.color),eu(n.fill,"color"),!e&&!n.fillOpacity&&(n.fillOpacity={value:0})),n.fillOpacity||(e?(n.fillOpacity=structuredClone(n.opacity),eu(n.fillOpacity,"opacity")):n.fillOpacity={value:0})}const K5=["none","diagonal","antiDiagonal","cross","vertical","horizontal","grid","dots","rings","ringsLarge"];class J5 extends No{constructor(t){super(t);R(this,Jn);this.augmentDefaultProperties({x2:void 0,y2:void 0,filled:!0,color:"#4c78a8",opacity:1,strokeWidth:3,cornerRadius:0,minWidth:.5,minHeight:.5,minOpacity:1})}getAttributes(){return["uniqueId","facetIndex","x","x2","y","y2","fill","stroke","fillOpacity","strokeOpacity","strokeWidth"]}getSupportedChannels(){return[...super.getSupportedChannels(),"x2","y2","fill","stroke","fillOpacity","strokeOpacity","strokeWidth"]}get opaque(){return Jc(this,"opaque",()=>!O(this,Jn,ad).call(this)&&!O(this,Jn,cd).call(this)&&!this.properties.shadowOpacity&&yt(this.encoding.fillOpacity)&&this.encoding.fillOpacity.value==1&&this.properties.minOpacity==1)&&this.unitView.getEffectiveOpacity()==1}fixEncoding(t){return rh(t,"x"),rh(t,"y"),F1(t,this.properties.filled),P1(t,this.properties.filled),delete t.color,delete t.opacity,t}onBeforeSampleAnimation(){}onAfterSampleAnimation(){}async initializeGraphics(){await super.initializeGraphics();const t=[];O(this,Jn,ad).call(this)&&t.push("ROUNDED_CORNERS"),O(this,Jn,cd).call(this)&&t.push("STROKED"),this.properties.shadowOpacity&&t.push("SHADOW"),this.createAndLinkShaders(zC,UC,[GC,...t.map(r=>"#define "+r)])}finalizeGraphicsInitialization(){super.finalizeGraphicsInitialization(),this.gl.useProgram(this.programInfo.program);const t=this.properties;this.registerMarkUniformValue("uMinWidth",t.minWidth),this.registerMarkUniformValue("uMinHeight",t.minHeight),this.registerMarkUniformValue("uMinOpacity",t.minOpacity),this.registerMarkUniformValue("uCornerRadiusTopRight",t.cornerRadiusTopRight??t.cornerRadius??0),this.registerMarkUniformValue("uCornerRadiusBottomRight",t.cornerRadiusBottomRight??t.cornerRadius??0),this.registerMarkUniformValue("uCornerRadiusTopLeft",t.cornerRadiusTopLeft??t.cornerRadius??0),this.registerMarkUniformValue("uCornerRadiusBottomLeft",t.cornerRadiusBottomLeft??t.cornerRadius??0),this.registerMarkUniformValue("uHatchPattern",t.hatch,r=>Math.max(0,K5.indexOf(r??"none"))),this.registerMarkUniformValue("uShadowBlur",t.shadowBlur??0),this.registerMarkUniformValue("uShadowOpacity",t.shadowOpacity??0),this.registerMarkUniformValue("uShadowOffsetX",t.shadowOffsetX??0),this.registerMarkUniformValue("uShadowOffsetY",t.shadowOffsetY??0),this.registerMarkUniformValue("uShadowColor",t.shadowColor??"black",$f)}updateGraphicsData(){const t=this.unitView.getCollector();if(!t){console.debug("No collector");return}const r=t.getItemCount(),i=new U5({encoders:this.encoders,attributes:this.getAttributes(),numItems:r});i.addBatches(t.facetBatches);const s=i.toArrays();this.rangeMap.migrateEntries(s.rangeMap),this.updateBufferInfo(s)}prepareRender(t){const r=super.prepareRender(t);return r.push(()=>this.bindOrSetMarkUniformBlock()),r.push(()=>wr(this.gl,this.programInfo,this.vertexArrayInfo)),r}render(t){const r=this.gl;return this.createRenderCallback((i,s)=>{Ac(r,this.vertexArrayInfo,r.TRIANGLE_STRIP,s,i)},t)}findDatumAt(t,r){t=He(t);const i=this.unitView.getCollector().facetBatches.get(t);if(!i)return;const s=this.encoders,o=s.x.scale.type;if(jn(o)){const a=s.x.dataAccessor;return i.find(c=>r==a(c))}else{const a=s.x.dataAccessor,c=s.x2.dataAccessor;return i.find(u=>r>=a(u)&&r<c(u))}}}Jn=new WeakSet,ad=function(){const t=this.properties;return t.cornerRadius||t.cornerRadiusBottomLeft||t.cornerRadiusBottomRight||t.cornerRadiusTopLeft||t.cornerRadiusTopRight},cd=function(){const t=this.encoding.strokeWidth;return!(yt(t)&&!t.value)||"condition"in t};const $5=`flat out float vRadius;flat out float vRadiusWithPadding;flat out lowp vec4 vFillColor;flat out lowp vec4 vStrokeColor;flat out lowp float vShape;flat out lowp float vHalfStrokeWidth;flat out mat2 vRotationMatrix;const float CIRCLE=0.0;const float SQUARE=1.0;const float CROSS=2.0;const float DIAMOND=3.0;const float TRIANGLE_UP=4.0;const float TRIANGLE_RIGHT=5.0;const float TRIANGLE_DOWN=6.0;const float TRIANGLE_LEFT=7.0;const float TICK_UP=8.0;const float TICK_RIGHT=9.0;const float TICK_DOWN=10.0;const float TICK_LEFT=11.0;float computeSemanticThresholdFactor(){return getScaled_semanticScore()>=uSemanticThreshold ? 1.0 : 0.0;}vec2 getDxDy(){
 #if defined(dx_DEFINED) || defined(dy_DEFINED)
 return vec2(getScaled_dx(),getScaled_dy())/uViewportSize;
 #else
 return vec2(0.0,0.0);
 #endif
-}void main(void){float shapeAngle=0.0;float semanticThresholdFactor=isPointSelected()? 1.0: computeSemanticThresholdFactor();if(semanticThresholdFactor<=0.0){gl_PointSize=0.0;gl_Position=vec4(100.0,0.0,0.0,0.0);return;}float size=getScaled_size();vec2 pos=vec2(getScaled_x(),getScaled_y())+getDxDy();gl_Position=unitToNdc(applySampleFacet(pos));float strokeWidth=getScaled_strokeWidth();float diameter=sqrt(size)*uScaleFactor*semanticThresholdFactor;float opacity=uViewOpacity;if(strokeWidth<=0.0||uInwardStroke){float minDiameter=1.0/uDevicePixelRatio;if(diameter<minDiameter){opacity*=pow(diameter/minDiameter,2.5);diameter=minDiameter;}}float fillOpa=getScaled_fillOpacity()*opacity;float strokeOpa=getScaled_strokeOpacity()*opacity;vShape=getScaled_shape();bool circle=vShape==0.0;if(vShape>TICK_UP&&vShape<=TICK_LEFT){shapeAngle=(vShape-TICK_UP)*90.0;vShape=TICK_UP;}else if(vShape>TRIANGLE_UP&&vShape<=TRIANGLE_LEFT){shapeAngle=(vShape-TRIANGLE_UP)*90.0;vShape=TRIANGLE_UP;}float angleInDegrees=getScaled_angle();float angle=-(shapeAngle+angleInDegrees)*PI/180.0;float sinTheta=sin(angle);float cosTheta=cos(angle);vRotationMatrix=mat2(cosTheta,sinTheta,-sinTheta,cosTheta);float roomForRotation=circle ? 1.0 : sin(mod(angle,PI/2.0)+PI/4.0)/sin(PI/4.0);float aaPadding=1.0/uDevicePixelRatio;float rotationPadding=(diameter*roomForRotation)-diameter;float strokePadding=uInwardStroke ? 0.0 : strokeWidth*(circle ? 1.0 : sqrt(3.0));float padding=rotationPadding+strokePadding+aaPadding;gl_PointSize=max((diameter+padding),uPickingEnabled ? uMinPickingSize : 0.0)*uDevicePixelRatio;vRadius=diameter/2.0;vRadiusWithPadding=vRadius+padding/2.0;vHalfStrokeWidth=strokeWidth/2.0;vFillColor=vec4(getScaled_fill()*fillOpa,fillOpa);vStrokeColor=vec4(getScaled_stroke()*strokeOpa,strokeOpa);setupPicking();}`,AD="const lowp vec4 white=vec4(1.0);const lowp vec4 black=vec4(0.0,0.0,0.0,1.0);flat in float vRadius;flat in float vRadiusWithPadding;flat in lowp vec4 vFillColor;flat in lowp vec4 vStrokeColor;flat in lowp float vShape;flat in lowp float vHalfStrokeWidth;flat in mat2 vRotationMatrix;out lowp vec4 fragColor;const float CIRCLE=0.0;const float SQUARE=1.0;const float CROSS=2.0;const float DIAMOND=3.0;const float TRIANGLE_UP=4.0;const float TICK_UP=8.0;float circle(vec2 p,float r){return length(p)-r;}float square(vec2 p,float r){p=abs(p);return max(p.x,p.y)-r;}float tickUp(vec2 p,float r){float halfR=r*0.5;p.y+=halfR;p=abs(p);return max(p.x-r*0.15,p.y-halfR);}float equilateralTriangle(vec2 p,float r){p.y=-p.y;float k=sqrt(3.0);float kr=k*r;p.y-=kr/2.0;return max((abs(p.x)*k+p.y)/2.0,-p.y-kr);}float crossShape(vec2 p,float r){p=abs(p);vec2 b=vec2(0.4,1.0)*r;vec2 v=abs(p)-b.xy;vec2 h=abs(p)-b.yx;return min(max(v.x,v.y),max(h.x,h.y));}float diamond(vec2 p,float r){p=abs(p);return(max(abs(p.x-p.y),abs(p.x+p.y))-r)/sqrt(2.0);}void main(){float d;vec2 p=vRotationMatrix*(2.0*gl_PointCoord-1.0)*vRadiusWithPadding;float r=vRadius;if(vShape==CIRCLE){d=circle(p,r);}else if(vShape==SQUARE){d=square(p,r);}else if(vShape==CROSS){d=crossShape(p,r);}else if(vShape==DIAMOND){d=diamond(p,r);}else if(vShape==TRIANGLE_UP){d=equilateralTriangle(p,r);}else if(vShape==TICK_UP){d=tickUp(p,r);}else{d=0.0;}if(!uPickingEnabled){lowp vec4 fillColor=mix(vFillColor,white,-d*uGradientStrength/vRadius);fragColor=distanceToColor(d+(uInwardStroke ? vHalfStrokeWidth : 0.0),fillColor,vStrokeColor,vec4(0.0),vHalfStrokeWidth);}else if(d-vHalfStrokeWidth<=0.0){fragColor=vPickingColor;}else{discard;}}",ED=`layout(std140)uniform Mark{/***The stroke should only grow inwards,e.g,the diameter/outline is not affected by the stroke width.*Thus,a point that has a zero size has no visible stroke. This allows strokes to be used with*geometric zoom,etc.*/uniform bool uInwardStroke;uniform float uMinPickingSize;uniform mediump float uScaleFactor;uniform mediump float uZoomLevel;uniform highp float uSemanticThreshold;uniform mediump float uGradientStrength;
+}void main(void){float shapeAngle=0.0;float semanticThresholdFactor=isPointSelected()? 1.0: computeSemanticThresholdFactor();if(semanticThresholdFactor<=0.0){gl_PointSize=0.0;gl_Position=vec4(100.0,0.0,0.0,0.0);return;}float size=getScaled_size();vec2 pos=vec2(getScaled_x(),getScaled_y())+getDxDy();gl_Position=unitToNdc(applySampleFacet(pos));float strokeWidth=getScaled_strokeWidth();float diameter=sqrt(size)*uScaleFactor*semanticThresholdFactor;float opacity=uViewOpacity;if(strokeWidth<=0.0||uInwardStroke){float minDiameter=1.0/uDevicePixelRatio;if(diameter<minDiameter){opacity*=pow(diameter/minDiameter,2.5);diameter=minDiameter;}}float fillOpa=getScaled_fillOpacity()*opacity;float strokeOpa=getScaled_strokeOpacity()*opacity;vShape=getScaled_shape();bool circle=vShape==0.0;if(vShape>TICK_UP&&vShape<=TICK_LEFT){shapeAngle=(vShape-TICK_UP)*90.0;vShape=TICK_UP;}else if(vShape>TRIANGLE_UP&&vShape<=TRIANGLE_LEFT){shapeAngle=(vShape-TRIANGLE_UP)*90.0;vShape=TRIANGLE_UP;}float angleInDegrees=getScaled_angle();float angle=-(shapeAngle+angleInDegrees)*PI/180.0;float sinTheta=sin(angle);float cosTheta=cos(angle);vRotationMatrix=mat2(cosTheta,sinTheta,-sinTheta,cosTheta);float roomForRotation=circle ? 1.0 : sin(mod(angle,PI/2.0)+PI/4.0)/sin(PI/4.0);float aaPadding=1.0/uDevicePixelRatio;float rotationPadding=(diameter*roomForRotation)-diameter;float strokePadding=uInwardStroke ? 0.0 : strokeWidth*(circle ? 1.0 : sqrt(3.0));float padding=rotationPadding+strokePadding+aaPadding;gl_PointSize=max((diameter+padding),uPickingEnabled ? uMinPickingSize : 0.0)*uDevicePixelRatio;vRadius=diameter/2.0;vRadiusWithPadding=vRadius+padding/2.0;vHalfStrokeWidth=strokeWidth/2.0;vFillColor=vec4(getScaled_fill()*fillOpa,fillOpa);vStrokeColor=vec4(getScaled_stroke()*strokeOpa,strokeOpa);setupPicking();}`,eD="const lowp vec4 white=vec4(1.0);const lowp vec4 black=vec4(0.0,0.0,0.0,1.0);flat in float vRadius;flat in float vRadiusWithPadding;flat in lowp vec4 vFillColor;flat in lowp vec4 vStrokeColor;flat in lowp float vShape;flat in lowp float vHalfStrokeWidth;flat in mat2 vRotationMatrix;out lowp vec4 fragColor;const float CIRCLE=0.0;const float SQUARE=1.0;const float CROSS=2.0;const float DIAMOND=3.0;const float TRIANGLE_UP=4.0;const float TICK_UP=8.0;float circle(vec2 p,float r){return length(p)-r;}float square(vec2 p,float r){p=abs(p);return max(p.x,p.y)-r;}float tickUp(vec2 p,float r){float halfR=r*0.5;p.y+=halfR;p=abs(p);return max(p.x-r*0.15,p.y-halfR);}float equilateralTriangle(vec2 p,float r){p.y=-p.y;float k=sqrt(3.0);float kr=k*r;p.y-=kr/2.0;return max((abs(p.x)*k+p.y)/2.0,-p.y-kr);}float crossShape(vec2 p,float r){p=abs(p);vec2 b=vec2(0.4,1.0)*r;vec2 v=abs(p)-b.xy;vec2 h=abs(p)-b.yx;return min(max(v.x,v.y),max(h.x,h.y));}float diamond(vec2 p,float r){p=abs(p);return(max(abs(p.x-p.y),abs(p.x+p.y))-r)/sqrt(2.0);}void main(){float d;vec2 p=vRotationMatrix*(2.0*gl_PointCoord-1.0)*vRadiusWithPadding;float r=vRadius;if(vShape==CIRCLE){d=circle(p,r);}else if(vShape==SQUARE){d=square(p,r);}else if(vShape==CROSS){d=crossShape(p,r);}else if(vShape==DIAMOND){d=diamond(p,r);}else if(vShape==TRIANGLE_UP){d=equilateralTriangle(p,r);}else if(vShape==TICK_UP){d=tickUp(p,r);}else{d=0.0;}if(!uPickingEnabled){lowp vec4 fillColor=mix(vFillColor,white,-d*uGradientStrength/vRadius);fragColor=distanceToColor(d+(uInwardStroke ? vHalfStrokeWidth : 0.0),fillColor,vStrokeColor,vec4(0.0),vHalfStrokeWidth);}else if(d-vHalfStrokeWidth<=0.0){fragColor=vPickingColor;}else{discard;}}",tD=`layout(std140)uniform Mark{/***The stroke should only grow inwards,e.g,the diameter/outline is not affected by the stroke width.*Thus,a point that has a zero size has no visible stroke. This allows strokes to be used with*geometric zoom,etc.*/uniform bool uInwardStroke;uniform float uMinPickingSize;uniform mediump float uScaleFactor;uniform mediump float uZoomLevel;uniform highp float uSemanticThreshold;uniform mediump float uGradientStrength;
 #pragma markUniforms
-};`;class ab extends yt{constructor(e){super(e),this.params=e,this.k=e.size||500,this.reset()}reset(){super.reset(),this.reservoir=[],this.W=void 0,this.ingester=this._initialIngester}_initialIngester(e){this.reservoir.push(e),this.reservoir.length==this.k&&(this.W=Math.exp(Math.log(Math.random())/this.k),this.i=this.k,this.next=this.i,this.ingester=this._finalIngester,this._setNextStop())}_finalIngester(e){++this.i==this.next&&(this.reservoir[Math.floor(Math.random()*this.k)]=e,this.W*=Math.exp(Math.log(Math.random())/this.k),this._setNextStop())}_setNextStop(){this.next+=Math.floor(Math.log(Math.random())/Math.log(1-this.W))+1}handle(e){this.ingester(e)}complete(){for(const e of this.reservoir)this._propagate(e);super.complete()}}function SD(t,e,n){const r=new ab({type:"sample",size:t});for(const o of e)r.handle(n(o));return r.complete(),r.reservoir}const CD={};class ID extends Aa{constructor(n){super(n);he(this,Eu);he(this,Yo,()=>0);this.augmentDefaultProperties({x:.5,y:.5,color:"#4c78a8",filled:!0,opacity:1,size:100,semanticScore:0,shape:"circle",strokeWidth:2,fillGradientStrength:0,dx:0,dy:0,angle:0,sampleFacetPadding:.1,semanticZoomFraction:.02,minPickingSize:2});const r=this.properties.semanticZoomFraction;if(r!=null)if(Ot(r)){const o=this.unitView.paramMediator.createExpression(r.expr);o.addListener(()=>this.getContext().animator.requestRender()),Ae(this,Yo,o)}else Ae(this,Yo,()=>r);"geometricZoomBound"in this.properties&&console.warn('geometricZoomBound is deprecated. Use something like the following instead: "size": { "expr": "min(0.5 * pow(zoomLevel, 2), 200)" }.')}getAttributes(){return["uniqueId","facetIndex","x","y","size","semanticScore","shape","strokeWidth","dx","dy","fill","stroke","fillOpacity","strokeOpacity","angle"]}getSupportedChannels(){return[...super.getSupportedChannels(),"size","semanticScore","shape","strokeWidth","dx","dy","fill","stroke","fillOpacity","strokeOpacity","angle"]}getDefaultEncoding(){return{...super.getDefaultEncoding(),...CD}}fixEncoding(n){return ob(n,this.properties.filled),sb(n,this.properties.filled),delete n.color,delete n.opacity,n}initializeData(){var r,o;super.initializeData();const n=(o=(r=this.encoders.semanticScore)==null?void 0:r.dataAccessor)==null?void 0:o.asNumberAccessor();n&&(this.sampledSemanticScores=Float32Array.from(SD(1e4,this.unitView.getCollector().getData(),n)),this.sampledSemanticScores.sort((i,s)=>i-s))}async initializeGraphics(){await super.initializeGraphics(),this.createAndLinkShaders(vD,AD,[ED])}finalizeGraphicsInitialization(){super.finalizeGraphicsInitialization(),this.gl.useProgram(this.programInfo.program);const n=this.properties;this.registerMarkUniformValue("uInwardStroke",n.inwardStroke,r=>!!r),this.registerMarkUniformValue("uGradientStrength",n.fillGradientStrength),this.registerMarkUniformValue("uMinPickingSize",n.minPickingSize)}updateGraphicsData(){const n=this.unitView.getCollector();if(!n){console.debug("No collector");return}const r=n.getItemCount(),o=new cD({encoders:this.encoders,attributes:this.getAttributes(),numItems:Math.max(r,this.properties.minBufferSize||0)});o.addBatches(n.facetBatches);const i=o.toArrays();this.rangeMap.migrateEntries(i.rangeMap),this.updateBufferInfo(i)}getSemanticThreshold(){if(this.sampledSemanticScores){const n=Math.max(0,1-j(this,Yo).call(this)*this.unitView.getZoomLevel());if(n<=0)return-1/0;if(n>=1)return 1/0;{const r=this.sampledSemanticScores;return Np(r,n)}}else return-1}prepareRender(n){const r=super.prepareRender(n);return r.push(()=>{Qs(this.markUniformInfo,{uScaleFactor:pe(this,Eu,Uv).call(this),uSemanticThreshold:this.getSemanticThreshold()}),this.markUniformsAltered=!0}),r.push(()=>this.bindOrSetMarkUniformBlock()),r.push(()=>ui(this.gl,this.programInfo,this.vertexArrayInfo)),r}render(n){const r=this.gl;return this.createRenderCallback((o,i)=>{i&&al(r,this.vertexArrayInfo,r.POINTS,i,o)},n)}}Yo=new WeakMap,Eu=new WeakSet,Uv=function(){const n=Math.pow(2,this.properties.geometricZoomBound||0);return Math.pow(Math.min(1,this.unitView.getZoomLevel()/n),1/3)};const TD="const int BUTT=0;const int SQUARE=1;const int ROUND=2;in float pos;in float side;flat out vec4 vColor;flat out float vSize;out float vNormalLengthInPixels;out highp vec2 vPosInPixels;void main(void){float pixelSize=1.0/uDevicePixelRatio;float size=getScaled_size();float opacity=getScaled_opacity()*uViewOpacity;if(size<pixelSize){opacity*=size/pixelSize;size=pixelSize;}vec2 a=applySampleFacet(vec2(getScaled_x(),getScaled_y()));vec2 b=applySampleFacet(vec2(getScaled_x2(),getScaled_y2()));vec2 tangent=b-a;float offset=0.0;float relativeDiff=0.0;if(uMinLength>0.0||uStrokeCap!=BUTT){float len=length(tangent*uViewportSize);float diff=max(0.0,uMinLength-len);if(uStrokeCap!=BUTT){diff+=size;}relativeDiff=diff/len;offset=relativeDiff*(pos-0.5);}vec2 p=pos<1.0? a+tangent*(pos+offset): b+tangent*offset;float aaPadding=pixelSize;vec2 normal=normalize(vec2(-tangent.y,tangent.x)/uViewportSize);p+=normal*side*(size+aaPadding)/uViewportSize;gl_Position=unitToNdc(p);vColor=vec4(getScaled_color()*opacity,opacity);vSize=size;vNormalLengthInPixels=side*(size+aaPadding);vPosInPixels=vec2(pos,(1.0-pos))*(1.0+relativeDiff)*length(tangent*uViewportSize)-vec2(uStrokeCap!=BUTT ? size/2.0 : 0.0);setupPicking();}",DD="const int BUTT=0;const int SQUARE=1;const int ROUND=2;uniform sampler2D uDashTexture;flat in vec4 vColor;flat in float vSize;in vec2 vPosInPixels;in float vNormalLengthInPixels;out lowp vec4 fragColor;void main(void){float dpr=uDevicePixelRatio;float distanceFromEnd=-min(vPosInPixels[0],vPosInPixels[1]);float distance;if(distanceFromEnd>0.0&&uStrokeCap==ROUND){distance=length(vec2(distanceFromEnd,vNormalLengthInPixels));}else{distance=abs(vNormalLengthInPixels);}float opacity=clamp(((vSize/2.0-distance)*dpr),-0.5,0.5)+0.5;if(uDashTextureSize>0.0){float pos=(vPosInPixels[0]+uStrokeDashOffset)*dpr;float floored=floor(pos);vec2 texelPositions=(floored+vec2(0.5,1.5))/dpr/uDashTextureSize;opacity*=mix(texture(uDashTexture,vec2(texelPositions[0],0)).r,texture(uDashTexture,vec2(texelPositions[1],0)).r,clamp((pos-floored),0.0,1.0));}fragColor=vColor*opacity;if(uPickingEnabled){fragColor=vPickingColor;}}",BD=`layout(std140)uniform Mark{uniform mediump float uMinLength;uniform mediump float uDashTextureSize;uniform lowp int uStrokeCap;uniform mediump float uStrokeDashOffset;
+};`;class M1 extends Te{constructor(e){super(e),this.params=e,this.k=e.size||500,this.reset()}reset(){super.reset(),this.reservoir=[],this.W=void 0,this.ingester=this._initialIngester}_initialIngester(e){this.reservoir.push(e),this.reservoir.length==this.k&&(this.W=Math.exp(Math.log(Math.random())/this.k),this.i=this.k,this.next=this.i,this.ingester=this._finalIngester,this._setNextStop())}_finalIngester(e){++this.i==this.next&&(this.reservoir[Math.floor(Math.random()*this.k)]=e,this.W*=Math.exp(Math.log(Math.random())/this.k),this._setNextStop())}_setNextStop(){this.next+=Math.floor(Math.log(Math.random())/Math.log(1-this.W))+1}handle(e){this.ingester(e)}complete(){for(const e of this.reservoir)this._propagate(e);super.complete()}}function nD(n,e,t){const r=new M1({type:"sample",size:n});for(const i of e)r.handle(t(i));return r.complete(),r.reservoir}const rD={};class iD extends No{constructor(t){super(t);R(this,Eu);R(this,rs,()=>0);this.augmentDefaultProperties({x:.5,y:.5,color:"#4c78a8",filled:!0,opacity:1,size:100,semanticScore:0,shape:"circle",strokeWidth:2,fillGradientStrength:0,dx:0,dy:0,angle:0,sampleFacetPadding:.1,semanticZoomFraction:.02,minPickingSize:2});const r=this.properties.semanticZoomFraction;if(r!=null)if(Qe(r)){const i=this.unitView.paramMediator.createExpression(r.expr);i.addListener(()=>this.getContext().animator.requestRender()),G(this,rs,i)}else G(this,rs,()=>r);"geometricZoomBound"in this.properties&&console.warn('geometricZoomBound is deprecated. Use something like the following instead: "size": { "expr": "min(0.5 * pow(zoomLevel, 2), 200)" }.')}getAttributes(){return["uniqueId","facetIndex","x","y","size","semanticScore","shape","strokeWidth","dx","dy","fill","stroke","fillOpacity","strokeOpacity","angle"]}getSupportedChannels(){return[...super.getSupportedChannels(),"size","semanticScore","shape","strokeWidth","dx","dy","fill","stroke","fillOpacity","strokeOpacity","angle"]}getDefaultEncoding(){return{...super.getDefaultEncoding(),...rD}}fixEncoding(t){return F1(t,this.properties.filled),P1(t,this.properties.filled),delete t.color,delete t.opacity,t}initializeData(){var r,i;super.initializeData();const t=(i=(r=this.encoders.semanticScore)==null?void 0:r.dataAccessor)==null?void 0:i.asNumberAccessor();t&&(this.sampledSemanticScores=Float32Array.from(nD(1e4,this.unitView.getCollector().getData(),t)),this.sampledSemanticScores.sort((s,o)=>s-o))}async initializeGraphics(){await super.initializeGraphics(),this.createAndLinkShaders($5,eD,[tD])}finalizeGraphicsInitialization(){super.finalizeGraphicsInitialization(),this.gl.useProgram(this.programInfo.program);const t=this.properties;this.registerMarkUniformValue("uInwardStroke",t.inwardStroke,r=>!!r),this.registerMarkUniformValue("uGradientStrength",t.fillGradientStrength),this.registerMarkUniformValue("uMinPickingSize",t.minPickingSize)}updateGraphicsData(){const t=this.unitView.getCollector();if(!t){console.debug("No collector");return}const r=t.getItemCount(),i=new H5({encoders:this.encoders,attributes:this.getAttributes(),numItems:Math.max(r,this.properties.minBufferSize||0)});i.addBatches(t.facetBatches);const s=i.toArrays();this.rangeMap.migrateEntries(s.rangeMap),this.updateBufferInfo(s)}getSemanticThreshold(){if(this.sampledSemanticScores){const t=Math.max(0,1-E(this,rs).call(this)*this.unitView.getZoomLevel());if(t<=0)return-1/0;if(t>=1)return 1/0;{const r=this.sampledSemanticScores;return l0(r,t)}}else return-1}prepareRender(t){const r=super.prepareRender(t);return r.push(()=>{ao(this.markUniformInfo,{uScaleFactor:O(this,Eu,xx).call(this),uSemanticThreshold:this.getSemanticThreshold()}),this.markUniformsAltered=!0}),r.push(()=>this.bindOrSetMarkUniformBlock()),r.push(()=>wr(this.gl,this.programInfo,this.vertexArrayInfo)),r}render(t){const r=this.gl;return this.createRenderCallback((i,s)=>{s&&Ac(r,this.vertexArrayInfo,r.POINTS,s,i)},t)}}rs=new WeakMap,Eu=new WeakSet,xx=function(){const t=Math.pow(2,this.properties.geometricZoomBound||0);return Math.pow(Math.min(1,this.unitView.getZoomLevel()/t),1/3)};const sD="const int BUTT=0;const int SQUARE=1;const int ROUND=2;in float pos;in float side;flat out vec4 vColor;flat out float vSize;out float vNormalLengthInPixels;out highp vec2 vPosInPixels;void main(void){float pixelSize=1.0/uDevicePixelRatio;float size=getScaled_size();float opacity=getScaled_opacity()*uViewOpacity;if(size<pixelSize){opacity*=size/pixelSize;size=pixelSize;}vec2 a=applySampleFacet(vec2(getScaled_x(),getScaled_y()));vec2 b=applySampleFacet(vec2(getScaled_x2(),getScaled_y2()));vec2 tangent=b-a;float offset=0.0;float relativeDiff=0.0;if(uMinLength>0.0||uStrokeCap!=BUTT){float len=length(tangent*uViewportSize);float diff=max(0.0,uMinLength-len);if(uStrokeCap!=BUTT){diff+=size;}relativeDiff=diff/len;offset=relativeDiff*(pos-0.5);}vec2 p=pos<1.0? a+tangent*(pos+offset): b+tangent*offset;float aaPadding=pixelSize;vec2 normal=normalize(vec2(-tangent.y,tangent.x)/uViewportSize);p+=normal*side*(size+aaPadding)/uViewportSize;gl_Position=unitToNdc(p);vColor=vec4(getScaled_color()*opacity,opacity);vSize=size;vNormalLengthInPixels=side*(size+aaPadding);vPosInPixels=vec2(pos,(1.0-pos))*(1.0+relativeDiff)*length(tangent*uViewportSize)-vec2(uStrokeCap!=BUTT ? size/2.0 : 0.0);setupPicking();}",oD="const int BUTT=0;const int SQUARE=1;const int ROUND=2;uniform sampler2D uDashTexture;flat in vec4 vColor;flat in float vSize;in vec2 vPosInPixels;in float vNormalLengthInPixels;out lowp vec4 fragColor;void main(void){float dpr=uDevicePixelRatio;float distanceFromEnd=-min(vPosInPixels[0],vPosInPixels[1]);float distance;if(distanceFromEnd>0.0&&uStrokeCap==ROUND){distance=length(vec2(distanceFromEnd,vNormalLengthInPixels));}else{distance=abs(vNormalLengthInPixels);}float opacity=clamp(((vSize/2.0-distance)*dpr),-0.5,0.5)+0.5;if(uDashTextureSize>0.0){float pos=(vPosInPixels[0]+uStrokeDashOffset)*dpr;float floored=floor(pos);vec2 texelPositions=(floored+vec2(0.5,1.5))/dpr/uDashTextureSize;opacity*=mix(texture(uDashTexture,vec2(texelPositions[0],0)).r,texture(uDashTexture,vec2(texelPositions[1],0)).r,clamp((pos-floored),0.0,1.0));}fragColor=vColor*opacity;if(uPickingEnabled){fragColor=vPickingColor;}}",aD=`layout(std140)uniform Mark{uniform mediump float uMinLength;uniform mediump float uDashTextureSize;uniform lowp int uStrokeCap;uniform mediump float uStrokeDashOffset;
 #pragma markUniforms
-};`;class kD extends Aa{constructor(e){super(e),this.dashTextureSize=0,this.augmentDefaultProperties({x2:void 0,y2:void 0,size:1,color:"black",opacity:1,minLength:0,strokeDash:null,strokeDashOffset:0,strokeCap:"butt"})}getAttributes(){return["uniqueId","facetIndex","x","x2","y","y2","size","color","opacity"]}getSupportedChannels(){return[...super.getSupportedChannels(),"x2","y2","size"]}fixEncoding(e){if(!(e.x&&e.y&&e.x2&&e.y2))if(e.x&&e.x2&&!e.y)e.y={value:.5},e.y2=e.y;else if(e.y&&e.y2&&!e.x)e.x={value:.5},e.x2=e.x;else if(e.x&&!e.y)e.y={value:0},e.y2={value:1},e.x2=e.x;else if(e.y&&!e.x)e.x={value:0},e.x2={value:1},e.y2=e.y;else if(e.x&&e.y&&e.y2)e.x2=e.x;else if(e.y&&e.x&&e.x2)e.y2=e.y;else if(e.y&&e.x)if(!e.x2&&$t(e.y)&&e.y.type=="quantitative")e.x2=e.x,e.y2={datum:0};else if(!e.y2&&$t(e.x)&&e.x.type=="quantitative")e.y2=e.y,e.x2={datum:0};else throw new Error("A bug!");else throw new Error("At a minimum, either the x or y channel must be defined in the rule mark's encoding: "+JSON.stringify(e));return e}async initializeGraphics(){await super.initializeGraphics();const e=this.gl,n=_D(this.properties.strokeDash);this.dashTexture=Ys(e,{level:0,mag:e.NEAREST,min:e.NEAREST,internalFormat:e.R8,format:e.RED,src:n,height:1}),this.dashTextureSize=n.length,this.createAndLinkShaders(TD,DD,[BD])}finalizeGraphicsInitialization(){super.finalizeGraphicsInitialization(),this.gl.useProgram(this.programInfo.program);const e=this.properties;this.registerMarkUniformValue("uMinLength",e.minLength),this.registerMarkUniformValue("uStrokeCap",e.strokeCap??"butt",n=>["butt","square","round"].indexOf(n)),Qs(this.markUniformInfo,{uDashTextureSize:+this.dashTextureSize}),this.markUniformsAltered=!0}updateGraphicsData(){const e=this.unitView.getCollector();if(!e){console.debug("No collector");return}const n=e.getItemCount(),r=new aD({encoders:this.encoders,attributes:this.getAttributes(),numItems:Math.max(n,this.properties.minBufferSize||0)});r.addBatches(e.facetBatches);const o=r.toArrays();this.rangeMap.migrateEntries(o.rangeMap),this.updateBufferInfo(o)}prepareRender(e){const n=super.prepareRender(e);return n.push(()=>this.bindOrSetMarkUniformBlock()),n.push(()=>li(this.programInfo,{uDashTexture:this.dashTexture})),n.push(()=>ui(this.gl,this.programInfo,this.vertexArrayInfo)),n}render(e){const n=this.gl;return this.createRenderCallback((r,o)=>al(n,this.vertexArrayInfo,n.TRIANGLE_STRIP,o,r),e)}}function _D(t){if(!t)return new Uint8Array(0);if(t.length==0||t.length%2||t.findIndex(i=>Math.round(i)!=i||i<1||i>1e3)>=0)throw new Error("Invalid stroke dash pattern: "+JSON.stringify(t));const e=t.reduce((i,s)=>i+s),n=new Uint8Array(e);let r=!0,o=0;for(let i of t){for(;i;)n[o++]=r&&255||0,i--;r=!r}return n}const RD="flat out vec4 vColor;flat out float vSize;out float vNormalLengthInPixels;flat out float vGamma;const int SHAPE_ARC=0;const int SHAPE_DOME=1;const int SHAPE_DIAGONAL=2;const int SHAPE_LINE=3;const int ORIENT_VERTICAL=0;const int ORIENT_HORIZONTAL=1;float distanceFromLine(vec2 pointOnLine1,vec2 pointOnLine2,vec2 point){vec2 a=point-pointOnLine1;vec2 b=pointOnLine2-pointOnLine1;vec2 proj=dot(a,b)/dot(b,b)*b;return length(a-proj);}bool isInsideViewport(vec2 point,float marginFactor){vec2 margin=uViewportSize*vec2(marginFactor);return point.x>=-margin.x&&point.x<=uViewportSize.x+margin.x&&point.y>=-margin.y&&point.y<=uViewportSize.y+margin.y;}void main(void){float pixelSize=1.0/uDevicePixelRatio;float opacity=getScaled_opacity()*uViewOpacity;vec2 p1,p2,p3,p4;vec2 a=applySampleFacet(vec2(getScaled_x(),getScaled_y()))*uViewportSize;vec2 b=applySampleFacet(vec2(getScaled_x2(),getScaled_y2()))*uViewportSize;if(uShape<=SHAPE_DOME){if(uShape==SHAPE_DOME){vec2 height=vec2(0.0);if(uOrient==ORIENT_VERTICAL){p1=vec2(min(a.x,b.x),b.y);p4=vec2(max(a.x,b.x),b.y);height=vec2(0.0,a.y-b.y);if(uClampApex){if(p4.x>0.0){p1.x=max(p1.x,-p4.x);}if(p1.x<uViewportSize.x){p4.x=min(p4.x,2.0*uViewportSize.x-p1.x);}}}else{p1=vec2(b.x,min(a.y,b.y));p4=vec2(b.x,max(a.y,b.y));height=vec2(a.x-b.x,0.0);if(uClampApex){if(p4.y>0.0){p1.y=max(p1.y,-p4.y);}if(p1.y<uViewportSize.y){p4.y=min(p4.y,2.0*uViewportSize.y-p1.y);}}}vec2 controlOffset=height/0.75;p2=p1+controlOffset;p3=p4+controlOffset;}if(uShape==SHAPE_ARC){p1=a;p4=b;vec2 chordVector=p4-p1;vec2 unitChordVector=normalize(chordVector);vec2 chordNormal=vec2(-unitChordVector.y,unitChordVector.x);float chordLength=length(chordVector);if(chordLength>uMaxChordLength){if(isInsideViewport(p1,2.0)){chordLength=uMaxChordLength;p4=p1+unitChordVector*uMaxChordLength;}else if(isInsideViewport(p4,2.0)){chordLength=uMaxChordLength;p1=p4-unitChordVector*uMaxChordLength;}}float height=max(chordLength/2.0*uArcHeightFactor,uMinArcHeight);vec2 controlOffset=chordNormal*height/0.75;p2=p1+controlOffset;p3=p4+controlOffset;}}else if(uShape==SHAPE_DIAGONAL){if(uOrient==ORIENT_VERTICAL){p1=a;p2=vec2(a.x,(a.y+b.y)/2.0);p3=vec2(b.x,(a.y+b.y)/2.0);p4=b;}else{p1=a;p2=vec2((a.x+b.x)/2.0,a.y);p3=vec2((a.x+b.x)/2.0,b.y);p4=b;}}else if(uShape==SHAPE_LINE){p1=a;p2=(a+b)/2.0;p3=p2;p4=b;}vec2 strip=vec2(float(gl_VertexID/2)/float(uSegmentBreaks),float(gl_VertexID % 2)-0.5);float t=smoothstep(0.0,1.0,strip.x);vec2 C1=p4-3.0*p3+3.0*p2-p1;vec2 C2=3.0*p3-6.0*p2+3.0*p1;vec2 C3=3.0*p2-3.0*p1;vec2 C4=p1;vec2 p;if(t==0.0){p=p1;}else if(t==1.0){p=p4;}else{p=C1*t*t*t+C2*t*t+C3*t+C4;}vec2 tangent=normalize(3.0*C1*t*t+2.0*C2*t+C3);vec2 normal=vec2(-tangent.y,tangent.x);float size=getScaled_size();if(size<pixelSize){opacity*=size/pixelSize;size=pixelSize;}float paddedSize=uPickingEnabled? max(size,uMinPickingSize): size+pixelSize;vNormalLengthInPixels=strip.y*paddedSize;if(uShape==SHAPE_ARC&&uArcFadingDistance[0]>0.0&&uArcFadingDistance[1]>0.0&&(!uNoFadingOnPointSelection||!isPointSelected())){float d=distanceFromLine(p1,p4,p);float distanceOpacity=smoothstep(uArcFadingDistance[1],uArcFadingDistance[0],d);opacity*=distanceOpacity;if(distanceOpacity<=0.0){vNormalLengthInPixels=0.0;}}p+=normal*vNormalLengthInPixels;gl_Position=pixelsToNdc(p);vec3 color=getScaled_color();vColor=vec4(color*opacity,opacity);vGamma=getGammaForColor(color);vSize=paddedSize;setupPicking();}",FD="flat in vec4 vColor;flat in float vSize;in float vNormalLengthInPixels;flat in float vGamma;out lowp vec4 fragColor;void main(void){float dpr=uDevicePixelRatio;float distance=abs(vNormalLengthInPixels);float opacity=clamp(((vSize/2.0-distance)*dpr),0.0,1.0);opacity=pow(opacity,vGamma);fragColor=vColor*opacity;if(uPickingEnabled){fragColor=vPickingColor;}}",MD=`layout(std140)uniform Mark{uniform float uArcHeightFactor;uniform float uMinArcHeight;uniform float uMinPickingSize;uniform int uShape;uniform int uOrient;uniform bool uClampApex;uniform float uMaxChordLength;uniform vec2 uArcFadingDistance;uniform bool uNoFadingOnPointSelection;uniform int uSegmentBreaks;
+};`;class cD extends No{constructor(e){super(e),this.dashTextureSize=0,this.augmentDefaultProperties({x2:void 0,y2:void 0,size:1,color:"black",opacity:1,minLength:0,strokeDash:null,strokeDashOffset:0,strokeCap:"butt"})}getAttributes(){return["uniqueId","facetIndex","x","x2","y","y2","size","color","opacity"]}getSupportedChannels(){return[...super.getSupportedChannels(),"x2","y2","size"]}fixEncoding(e){if(!(e.x&&e.y&&e.x2&&e.y2))if(e.x&&e.x2&&!e.y)e.y={value:.5},e.y2=e.y;else if(e.y&&e.y2&&!e.x)e.x={value:.5},e.x2=e.x;else if(e.x&&!e.y)e.y={value:0},e.y2={value:1},e.x2=e.x;else if(e.y&&!e.x)e.x={value:0},e.x2={value:1},e.y2=e.y;else if(e.x&&e.y&&e.y2)e.x2=e.x;else if(e.y&&e.x&&e.x2)e.y2=e.y;else if(e.y&&e.x)if(!e.x2&&lt(e.y)&&e.y.type=="quantitative")e.x2=e.x,e.y2={datum:0};else if(!e.y2&&lt(e.x)&&e.x.type=="quantitative")e.y2=e.y,e.x2={datum:0};else throw new Error("A bug!");else throw new Error("At a minimum, either the x or y channel must be defined in the rule mark's encoding: "+JSON.stringify(e));return e}async initializeGraphics(){await super.initializeGraphics();const e=this.gl,t=uD(this.properties.strokeDash);this.dashTexture=oo(e,{level:0,mag:e.NEAREST,min:e.NEAREST,internalFormat:e.R8,format:e.RED,src:t,height:1}),this.dashTextureSize=t.length,this.createAndLinkShaders(sD,oD,[aD])}finalizeGraphicsInitialization(){super.finalizeGraphicsInitialization(),this.gl.useProgram(this.programInfo.program);const e=this.properties;this.registerMarkUniformValue("uMinLength",e.minLength),this.registerMarkUniformValue("uStrokeCap",e.strokeCap??"butt",t=>["butt","square","round"].indexOf(t)),ao(this.markUniformInfo,{uDashTextureSize:+this.dashTextureSize}),this.markUniformsAltered=!0}updateGraphicsData(){const e=this.unitView.getCollector();if(!e){console.debug("No collector");return}const t=e.getItemCount(),r=new G5({encoders:this.encoders,attributes:this.getAttributes(),numItems:Math.max(t,this.properties.minBufferSize||0)});r.addBatches(e.facetBatches);const i=r.toArrays();this.rangeMap.migrateEntries(i.rangeMap),this.updateBufferInfo(i)}prepareRender(e){const t=super.prepareRender(e);return t.push(()=>this.bindOrSetMarkUniformBlock()),t.push(()=>Ar(this.programInfo,{uDashTexture:this.dashTexture})),t.push(()=>wr(this.gl,this.programInfo,this.vertexArrayInfo)),t}render(e){const t=this.gl;return this.createRenderCallback((r,i)=>Ac(t,this.vertexArrayInfo,t.TRIANGLE_STRIP,i,r),e)}}function uD(n){if(!n)return new Uint8Array(0);if(n.length==0||n.length%2||n.findIndex(s=>Math.round(s)!=s||s<1||s>1e3)>=0)throw new Error("Invalid stroke dash pattern: "+JSON.stringify(n));const e=n.reduce((s,o)=>s+o),t=new Uint8Array(e);let r=!0,i=0;for(let s of n){for(;s;)t[i++]=r&&255||0,s--;r=!r}return t}const lD="flat out vec4 vColor;flat out float vSize;out float vNormalLengthInPixels;flat out float vGamma;const int SHAPE_ARC=0;const int SHAPE_DOME=1;const int SHAPE_DIAGONAL=2;const int SHAPE_LINE=3;const int ORIENT_VERTICAL=0;const int ORIENT_HORIZONTAL=1;float distanceFromLine(vec2 pointOnLine1,vec2 pointOnLine2,vec2 point){vec2 a=point-pointOnLine1;vec2 b=pointOnLine2-pointOnLine1;vec2 proj=dot(a,b)/dot(b,b)*b;return length(a-proj);}bool isInsideViewport(vec2 point,float marginFactor){vec2 margin=uViewportSize*vec2(marginFactor);return point.x>=-margin.x&&point.x<=uViewportSize.x+margin.x&&point.y>=-margin.y&&point.y<=uViewportSize.y+margin.y;}void main(void){float pixelSize=1.0/uDevicePixelRatio;float opacity=getScaled_opacity()*uViewOpacity;vec2 p1,p2,p3,p4;vec2 a=applySampleFacet(vec2(getScaled_x(),getScaled_y()))*uViewportSize;vec2 b=applySampleFacet(vec2(getScaled_x2(),getScaled_y2()))*uViewportSize;if(uShape<=SHAPE_DOME){if(uShape==SHAPE_DOME){vec2 height=vec2(0.0);if(uOrient==ORIENT_VERTICAL){p1=vec2(min(a.x,b.x),b.y);p4=vec2(max(a.x,b.x),b.y);height=vec2(0.0,a.y-b.y);if(uClampApex){if(p4.x>0.0){p1.x=max(p1.x,-p4.x);}if(p1.x<uViewportSize.x){p4.x=min(p4.x,2.0*uViewportSize.x-p1.x);}}}else{p1=vec2(b.x,min(a.y,b.y));p4=vec2(b.x,max(a.y,b.y));height=vec2(a.x-b.x,0.0);if(uClampApex){if(p4.y>0.0){p1.y=max(p1.y,-p4.y);}if(p1.y<uViewportSize.y){p4.y=min(p4.y,2.0*uViewportSize.y-p1.y);}}}vec2 controlOffset=height/0.75;p2=p1+controlOffset;p3=p4+controlOffset;}if(uShape==SHAPE_ARC){p1=a;p4=b;vec2 chordVector=p4-p1;vec2 unitChordVector=normalize(chordVector);vec2 chordNormal=vec2(-unitChordVector.y,unitChordVector.x);float chordLength=length(chordVector);if(chordLength>uMaxChordLength){if(isInsideViewport(p1,2.0)){chordLength=uMaxChordLength;p4=p1+unitChordVector*uMaxChordLength;}else if(isInsideViewport(p4,2.0)){chordLength=uMaxChordLength;p1=p4-unitChordVector*uMaxChordLength;}}float height=max(chordLength/2.0*uArcHeightFactor,uMinArcHeight);vec2 controlOffset=chordNormal*height/0.75;p2=p1+controlOffset;p3=p4+controlOffset;}}else if(uShape==SHAPE_DIAGONAL){if(uOrient==ORIENT_VERTICAL){p1=a;p2=vec2(a.x,(a.y+b.y)/2.0);p3=vec2(b.x,(a.y+b.y)/2.0);p4=b;}else{p1=a;p2=vec2((a.x+b.x)/2.0,a.y);p3=vec2((a.x+b.x)/2.0,b.y);p4=b;}}else if(uShape==SHAPE_LINE){p1=a;p2=(a+b)/2.0;p3=p2;p4=b;}vec2 strip=vec2(float(gl_VertexID/2)/float(uSegmentBreaks),float(gl_VertexID % 2)-0.5);float t=smoothstep(0.0,1.0,strip.x);vec2 C1=p4-3.0*p3+3.0*p2-p1;vec2 C2=3.0*p3-6.0*p2+3.0*p1;vec2 C3=3.0*p2-3.0*p1;vec2 C4=p1;vec2 p;if(t==0.0){p=p1;}else if(t==1.0){p=p4;}else{p=C1*t*t*t+C2*t*t+C3*t+C4;}vec2 tangent=normalize(3.0*C1*t*t+2.0*C2*t+C3);vec2 normal=vec2(-tangent.y,tangent.x);float size=getScaled_size();if(size<pixelSize){opacity*=size/pixelSize;size=pixelSize;}float paddedSize=uPickingEnabled? max(size,uMinPickingSize): size+pixelSize;vNormalLengthInPixels=strip.y*paddedSize;if(uShape==SHAPE_ARC&&uArcFadingDistance[0]>0.0&&uArcFadingDistance[1]>0.0&&(!uNoFadingOnPointSelection||!isPointSelected())){float d=distanceFromLine(p1,p4,p);float distanceOpacity=smoothstep(uArcFadingDistance[1],uArcFadingDistance[0],d);opacity*=distanceOpacity;if(distanceOpacity<=0.0){vNormalLengthInPixels=0.0;}}p+=normal*vNormalLengthInPixels;gl_Position=pixelsToNdc(p);vec3 color=getScaled_color();vColor=vec4(color*opacity,opacity);vGamma=getGammaForColor(color);vSize=paddedSize;setupPicking();}",fD="flat in vec4 vColor;flat in float vSize;in float vNormalLengthInPixels;flat in float vGamma;out lowp vec4 fragColor;void main(void){float dpr=uDevicePixelRatio;float distance=abs(vNormalLengthInPixels);float opacity=clamp(((vSize/2.0-distance)*dpr),0.0,1.0);opacity=pow(opacity,vGamma);fragColor=vColor*opacity;if(uPickingEnabled){fragColor=vPickingColor;}}",hD=`layout(std140)uniform Mark{uniform float uArcHeightFactor;uniform float uMinArcHeight;uniform float uMinPickingSize;uniform int uShape;uniform int uOrient;uniform bool uClampApex;uniform float uMaxChordLength;uniform vec2 uArcFadingDistance;uniform bool uNoFadingOnPointSelection;uniform int uSegmentBreaks;
 #pragma markUniforms
-};`,PD=["arc","dome","diagonal","line"],LD=["vertical","horizontal"];class OD extends Aa{constructor(e){super(e),this.augmentDefaultProperties({x:0,x2:void 0,y:0,y2:void 0,size:1,color:"black",opacity:1,segments:101,arcHeightFactor:1,minArcHeight:1.5,minPickingSize:3,clampApex:!1,maxChordLength:5e4,arcFadingDistance:!1,noFadingOnPointSelection:!0,linkShape:"arc",orient:"vertical"}),this._baseInstanceExt=this.gl.getExtension("WEBGL_draw_instanced_base_vertex_base_instance")}get defaultHitTestMode(){return"endpoints"}getAttributes(){return["uniqueId","facetIndex","x","x2","y","y2","size","color","opacity"]}getSupportedChannels(){return[...super.getSupportedChannels(),"x2","y2","size"]}fixEncoding(e){return e.x2||($t(e.x)?e.x2={datum:0}:e.x2=e.x),e.y2||($t(e.y)?e.y2={datum:0}:e.y2=e.y),e}async initializeGraphics(){await super.initializeGraphics(),this.createAndLinkShaders(RD,FD,[MD])}finalizeGraphicsInitialization(){super.finalizeGraphicsInitialization(),this.gl.useProgram(this.programInfo.program);const e=this.properties;this.registerMarkUniformValue("uArcFadingDistance",e.arcFadingDistance,n=>n||[0,0]),this.registerMarkUniformValue("uArcHeightFactor",e.arcHeightFactor),this.registerMarkUniformValue("uMinArcHeight",e.minArcHeight),this.registerMarkUniformValue("uMinPickingSize",e.minPickingSize),this.registerMarkUniformValue("uShape",e.linkShape,n=>PD.indexOf(n)),this.registerMarkUniformValue("uOrient",e.orient,n=>LD.indexOf(n)),this.registerMarkUniformValue("uClampApex",e.clampApex,n=>!!n),this.registerMarkUniformValue("uMaxChordLength",e.maxChordLength),this.registerMarkUniformValue("uSegmentBreaks",e.segments,n=>n),this.registerMarkUniformValue("uNoFadingOnPointSelection",e.noFadingOnPointSelection,n=>!!n)}updateGraphicsData(){const e=this.unitView.getCollector();if(!e){console.debug("No collector");return}const n=e.getItemCount(),r=new lD({encoders:this.encoders,attributes:this.getAttributes(),numItems:n});r.addBatches(e.facetBatches);const o=r.toArrays();this.rangeMap.migrateEntries(o.rangeMap),this.arrays=Object.fromEntries(Object.entries(o.arrays).map(([i,s])=>[i,{...s,data:void 0}])),this.updateBufferInfo(o)}prepareRender(e){const n=super.prepareRender(e);return n.push(()=>this.bindOrSetMarkUniformBlock()),this._baseInstanceExt?n.push(()=>ui(this.gl,this.programInfo,this.vertexArrayInfo)):n.push(()=>this.gl.bindVertexArray(null)),n}render(e){const n=this.gl,r=()=>(this.markUniformInfo.uniforms.uSegmentBreaks[0]+1)*2;return this._baseInstanceExt?this.createRenderCallback((o,i)=>{this._baseInstanceExt.drawArraysInstancedBaseInstanceWEBGL(n.TRIANGLE_STRIP,0,r(),i,o)},e):this.createRenderCallback((o,i)=>{for(const s of Object.entries(this.bufferInfo.attribs)){const[a,c]=s;c.buffer&&c.numComponents&&c.divisor&&(c.offset=o*this.arrays[a].numComponents*this.bytesPerElement.get(a))}ui(n,this.programInfo,this.bufferInfo),n.drawArraysInstanced(n.TRIANGLE_STRIP,0,r(),i)},e)}}const ND=`in mediump vec2 vertexCoord;in lowp vec2 textureCoord;in float width;out vec2 vTexCoord;out float vEdgeFadeOpacity;flat out vec4 vColor;flat out float vSlope;flat out float vGamma;struct RangeResult{float pos;float scale;};float minValue(vec4 v){return min(min(v.x,v.y),min(v.z,v.w));}float maxValue(vec4 v){return max(max(v.x,v.y),max(v.z,v.w));}/***All measures are in[0,1]*/RangeResult positionInsideRange(float a,float b,float width,float padding,int align,bool flush){float span=b-a;float paddedWidth=width+2.0*padding;if(a>1.0||b<0.0){return RangeResult(0.0,0.0);}float extra=max(0.0,span-paddedWidth);float pos;if(align==0){float centre=a+b;if(flush){float leftOver=max(0.0,paddedWidth-centre);centre+=min(leftOver,extra);float rightOver=max(0.0,paddedWidth+centre-2.0);centre-=min(rightOver,extra);}pos=centre/2.0;}else if(align<0){float edge=a;if(flush){float over=max(0.0,-edge);edge+=min(over,extra);}pos=edge+padding;}else{float edge=b;if(flush){float over=max(0.0,edge-1.0);edge-=min(over,extra);}pos=edge-padding;}float scale=clamp((span-padding)/paddedWidth,0.0,1.0);return RangeResult(pos,scale);}vec2 calculateRotatedDimensions(float width,mat2 rotationMatrix){vec2 a=abs(rotationMatrix*vec2(width/2.0,0.5));vec2 b=abs(rotationMatrix*vec2(width/2.0,-0.5));return vec2(max(a.x,b.x),max(a.y,b.y))*2.0;}ivec2 fixAlignForAngle(ivec2 align,float angleInDegrees){float a=mod(angleInDegrees+45.0,360.0);int x=align.x;int y=-align.y;if(a<90.0){return ivec2(x,y);}else if(a<180.0){return ivec2(y,-x);}else if(a<270.0){return ivec2(-x,y);}else{return ivec2(-y,x);}}void main(void){float opacity=getScaled_opacity()*uViewOpacity;vec2 size=vec2(getScaled_size());float x=getScaled_x();float y=getScaled_y();float scale=1.0;float angleInDegrees=getScaled_angle();float angle=-angleInDegrees*PI/180.0;float sinTheta=sin(angle);float cosTheta=cos(angle);mat2 rotationMatrix=mat2(cosTheta,sinTheta,-sinTheta,cosTheta);vec2 flushSize=calculateRotatedDimensions(width,rotationMatrix);
+};`,dD=["arc","dome","diagonal","line"],pD=["vertical","horizontal"];class mD extends No{constructor(e){super(e),this.augmentDefaultProperties({x:0,x2:void 0,y:0,y2:void 0,size:1,color:"black",opacity:1,segments:101,arcHeightFactor:1,minArcHeight:1.5,minPickingSize:3,clampApex:!1,maxChordLength:5e4,arcFadingDistance:!1,noFadingOnPointSelection:!0,linkShape:"arc",orient:"vertical"}),this._baseInstanceExt=this.gl.getExtension("WEBGL_draw_instanced_base_vertex_base_instance")}get defaultHitTestMode(){return"endpoints"}getAttributes(){return["uniqueId","facetIndex","x","x2","y","y2","size","color","opacity"]}getSupportedChannels(){return[...super.getSupportedChannels(),"x2","y2","size"]}fixEncoding(e){return e.x2||(lt(e.x)?e.x2={datum:0}:e.x2=e.x),e.y2||(lt(e.y)?e.y2={datum:0}:e.y2=e.y),e}async initializeGraphics(){await super.initializeGraphics(),this.createAndLinkShaders(lD,fD,[hD])}finalizeGraphicsInitialization(){super.finalizeGraphicsInitialization(),this.gl.useProgram(this.programInfo.program);const e=this.properties;this.registerMarkUniformValue("uArcFadingDistance",e.arcFadingDistance,t=>t||[0,0]),this.registerMarkUniformValue("uArcHeightFactor",e.arcHeightFactor),this.registerMarkUniformValue("uMinArcHeight",e.minArcHeight),this.registerMarkUniformValue("uMinPickingSize",e.minPickingSize),this.registerMarkUniformValue("uShape",e.linkShape,t=>dD.indexOf(t)),this.registerMarkUniformValue("uOrient",e.orient,t=>pD.indexOf(t)),this.registerMarkUniformValue("uClampApex",e.clampApex,t=>!!t),this.registerMarkUniformValue("uMaxChordLength",e.maxChordLength),this.registerMarkUniformValue("uSegmentBreaks",e.segments,t=>t),this.registerMarkUniformValue("uNoFadingOnPointSelection",e.noFadingOnPointSelection,t=>!!t)}updateGraphicsData(){const e=this.unitView.getCollector();if(!e){console.debug("No collector");return}const t=e.getItemCount(),r=new V5({encoders:this.encoders,attributes:this.getAttributes(),numItems:t});r.addBatches(e.facetBatches);const i=r.toArrays();this.rangeMap.migrateEntries(i.rangeMap),this.arrays=Object.fromEntries(Object.entries(i.arrays).map(([s,o])=>[s,{...o,data:void 0}])),this.updateBufferInfo(i)}prepareRender(e){const t=super.prepareRender(e);return t.push(()=>this.bindOrSetMarkUniformBlock()),this._baseInstanceExt?t.push(()=>wr(this.gl,this.programInfo,this.vertexArrayInfo)):t.push(()=>this.gl.bindVertexArray(null)),t}render(e){const t=this.gl,r=()=>(this.markUniformInfo.uniforms.uSegmentBreaks[0]+1)*2;return this._baseInstanceExt?this.createRenderCallback((i,s)=>{this._baseInstanceExt.drawArraysInstancedBaseInstanceWEBGL(t.TRIANGLE_STRIP,0,r(),s,i)},e):this.createRenderCallback((i,s)=>{for(const o of Object.entries(this.bufferInfo.attribs)){const[a,c]=o;c.buffer&&c.numComponents&&c.divisor&&(c.offset=i*this.arrays[a].numComponents*this.bytesPerElement.get(a))}wr(t,this.programInfo,this.bufferInfo),t.drawArraysInstanced(t.TRIANGLE_STRIP,0,r(),s)},e)}}const gD=`in mediump vec2 vertexCoord;in lowp vec2 textureCoord;in float width;out vec2 vTexCoord;out float vEdgeFadeOpacity;flat out vec4 vColor;flat out float vSlope;flat out float vGamma;struct RangeResult{float pos;float scale;};float minValue(vec4 v){return min(min(v.x,v.y),min(v.z,v.w));}float maxValue(vec4 v){return max(max(v.x,v.y),max(v.z,v.w));}/***All measures are in[0,1]*/RangeResult positionInsideRange(float a,float b,float width,float padding,int align,bool flush){float span=b-a;float paddedWidth=width+2.0*padding;if(a>1.0||b<0.0){return RangeResult(0.0,0.0);}float extra=max(0.0,span-paddedWidth);float pos;if(align==0){float centre=a+b;if(flush){float leftOver=max(0.0,paddedWidth-centre);centre+=min(leftOver,extra);float rightOver=max(0.0,paddedWidth+centre-2.0);centre-=min(rightOver,extra);}pos=centre/2.0;}else if(align<0){float edge=a;if(flush){float over=max(0.0,-edge);edge+=min(over,extra);}pos=edge+padding;}else{float edge=b;if(flush){float over=max(0.0,edge-1.0);edge-=min(over,extra);}pos=edge-padding;}float scale=clamp((span-padding)/paddedWidth,0.0,1.0);return RangeResult(pos,scale);}vec2 calculateRotatedDimensions(float width,mat2 rotationMatrix){vec2 a=abs(rotationMatrix*vec2(width/2.0,0.5));vec2 b=abs(rotationMatrix*vec2(width/2.0,-0.5));return vec2(max(a.x,b.x),max(a.y,b.y))*2.0;}ivec2 fixAlignForAngle(ivec2 align,float angleInDegrees){float a=mod(angleInDegrees+45.0,360.0);int x=align.x;int y=-align.y;if(a<90.0){return ivec2(x,y);}else if(a<180.0){return ivec2(y,-x);}else if(a<270.0){return ivec2(-x,y);}else{return ivec2(-y,x);}}void main(void){float opacity=getScaled_opacity()*uViewOpacity;vec2 size=vec2(getScaled_size());float x=getScaled_x();float y=getScaled_y();float scale=1.0;float angleInDegrees=getScaled_angle();float angle=-angleInDegrees*PI/180.0;float sinTheta=sin(angle);float cosTheta=cos(angle);mat2 rotationMatrix=mat2(cosTheta,sinTheta,-sinTheta,cosTheta);vec2 flushSize=calculateRotatedDimensions(width,rotationMatrix);
 #if defined(x2_DEFINED) || defined(y2_DEFINED)
 ivec2 align=fixAlignForAngle(uAlign,angleInDegrees);
 #else
@@ -470,9 +470,9 @@ vec2 pos=applySampleFacet(vec2(x,y));
 #ifdef y2_DEFINED
 float y2=getScaled_y2();vec2 pos2=applySampleFacet(vec2(x,y2));if(uLogoLetter){size.y=(pos2.y-pos.y)*uViewportSize.y;pos.y+=(pos2.y-pos.y)/2.0;}else{RangeResult result=positionInsideRange(min(pos.y,pos2.y),max(pos.y,pos2.y),size.y*scale*flushSize.y/uViewportSize.y,uPaddingY/uViewportSize.y,align.y,uFlushY);pos.y=result.pos;scale*=result.scale;}
 #endif
-if(scale<1.0){if(uSqueeze){vec2 scaleFadeExtent=vec2(3.0,6.0)/size;if(scale<scaleFadeExtent[0]){gl_Position=vec4(0.0);return;}size*=scale;opacity*=linearstep(scaleFadeExtent[0],scaleFadeExtent[1],scale);}else if(scale<1.0){gl_Position=vec4(0.0);return;}}vec2 charPos=rotationMatrix*(vertexCoord*size+uD);vec2 unitPos=pos+charPos/uViewportSize;gl_Position=unitToNdc(unitPos);vSlope=max(1.0,min(size.x,size.y)/uSdfNumerator*uDevicePixelRatio);vec3 color=getScaled_color();vColor=vec4(color*opacity,opacity);vGamma=getGammaForColor(color);vTexCoord=textureCoord;if(maxValue(uViewportEdgeFadeDistance)>-pow(10.0,10.0)){vEdgeFadeOpacity=minValue(((vec4(1.0,1.0,0.0,0.0)+vec4(-1.0,-1.0,1.0,1.0)*unitPos.yxyx)*uViewportSize.yxyx-uViewportEdgeFadeDistance)/uViewportEdgeFadeWidth);}else{vEdgeFadeOpacity=1.0;}setupPicking();}`,zD="uniform sampler2D uTexture;in vec2 vTexCoord;in float vEdgeFadeOpacity;flat in vec4 vColor;flat in float vSlope;flat in float vGamma;out lowp vec4 fragColor;float median(float r,float g,float b){return max(min(r,g),min(max(r,g),b));}float getDist(vec2 uv){vec3 c=texture(uTexture,uv).rgb;return 1.0-median(c.r,c.g,c.b);}/***Calculates the super-sampled distance to the edge.*This is used to avoid aliasing when rendering small text,*as mip-mapping cannot be used here.*The distance is averaged over a grid of n x n samples.*/float getSuperDist(vec2 uv){vec2 dx=dFdx(uv);vec2 dy=dFdy(uv);float n=2.0;float sum=0.0;for(float x=0.5;x<n;x++){for(float y=0.5;y<n;y++){sum+=getDist(uv+x/n*dx+y/n*dy);}}return sum/(n*n);}void main(){float sigDist=getSuperDist(vTexCoord);float slope=vSlope;if(uLogoLetter){slope=0.7/length(vec2(dFdy(sigDist),dFdx(sigDist)));}float opa=clamp((sigDist-0.5)*slope+0.5,0.0,1.0);opa*=clamp(vEdgeFadeOpacity,0.0,1.0);opa=pow(opa,vGamma);fragColor=vColor*opa;if(uPickingEnabled){fragColor=vPickingColor;}}",UD=`layout(std140)uniform Mark{uniform mediump float uSdfNumerator;uniform mediump vec2 uD;uniform mediump vec4 uViewportEdgeFadeWidth;uniform mediump vec4 uViewportEdgeFadeDistance;uniform bool uSqueeze;uniform bool uLogoLetter;uniform lowp ivec2 uAlign;uniform mediump float uPaddingX;uniform bool uFlushX;uniform mediump float uPaddingY;uniform bool uFlushY;
+if(scale<1.0){if(uSqueeze){vec2 scaleFadeExtent=vec2(3.0,6.0)/size;if(scale<scaleFadeExtent[0]){gl_Position=vec4(0.0);return;}size*=scale;opacity*=linearstep(scaleFadeExtent[0],scaleFadeExtent[1],scale);}else if(scale<1.0){gl_Position=vec4(0.0);return;}}vec2 charPos=rotationMatrix*(vertexCoord*size+uD);vec2 unitPos=pos+charPos/uViewportSize;gl_Position=unitToNdc(unitPos);vSlope=max(1.0,min(size.x,size.y)/uSdfNumerator*uDevicePixelRatio);vec3 color=getScaled_color();vColor=vec4(color*opacity,opacity);vGamma=getGammaForColor(color);vTexCoord=textureCoord;if(maxValue(uViewportEdgeFadeDistance)>-pow(10.0,10.0)){vEdgeFadeOpacity=minValue(((vec4(1.0,1.0,0.0,0.0)+vec4(-1.0,-1.0,1.0,1.0)*unitPos.yxyx)*uViewportSize.yxyx-uViewportEdgeFadeDistance)/uViewportEdgeFadeWidth);}else{vEdgeFadeOpacity=1.0;}setupPicking();}`,yD="uniform sampler2D uTexture;in vec2 vTexCoord;in float vEdgeFadeOpacity;flat in vec4 vColor;flat in float vSlope;flat in float vGamma;out lowp vec4 fragColor;float median(float r,float g,float b){return max(min(r,g),min(max(r,g),b));}float getDist(vec2 uv){vec3 c=texture(uTexture,uv).rgb;return 1.0-median(c.r,c.g,c.b);}/***Calculates the super-sampled distance to the edge.*This is used to avoid aliasing when rendering small text,*as mip-mapping cannot be used here.*The distance is averaged over a grid of n x n samples.*/float getSuperDist(vec2 uv){vec2 dx=dFdx(uv);vec2 dy=dFdy(uv);float n=2.0;float sum=0.0;for(float x=0.5;x<n;x++){for(float y=0.5;y<n;y++){sum+=getDist(uv+x/n*dx+y/n*dy);}}return sum/(n*n);}void main(){float sigDist=getSuperDist(vTexCoord);float slope=vSlope;if(uLogoLetter){slope=0.7/length(vec2(dFdy(sigDist),dFdx(sigDist)));}float opa=clamp((sigDist-0.5)*slope+0.5,0.0,1.0);opa*=clamp(vEdgeFadeOpacity,0.0,1.0);opa=pow(opa,vGamma);fragColor=vColor*opa;if(uPickingEnabled){fragColor=vPickingColor;}}",bD=`layout(std140)uniform Mark{uniform mediump float uSdfNumerator;uniform mediump vec2 uD;uniform mediump vec4 uViewportEdgeFadeWidth;uniform mediump vec4 uViewportEdgeFadeDistance;uniform bool uSqueeze;uniform bool uLogoLetter;uniform lowp ivec2 uAlign;uniform mediump float uPaddingX;uniform bool uFlushX;uniform mediump float uPaddingY;uniform bool uFlushY;
 #pragma markUniforms
-};`,GD={left:-1,center:0,right:1},HD={top:-1,middle:0,bottom:1,alphabetic:1};class VD extends Aa{constructor(e){super(e),this.augmentDefaultProperties({x:.5,y:.5,x2:void 0,y2:void 0,text:"",size:11,color:"black",opacity:1,font:void 0,fontStyle:void 0,fontWeight:void 0,align:"center",baseline:"middle",dx:0,dy:0,angle:0,fitToBand:!1,squeeze:!0,paddingX:0,paddingY:0,flushX:!0,flushY:!0,logoLetters:!1,viewportEdgeFadeWidthTop:0,viewportEdgeFadeWidthRight:0,viewportEdgeFadeWidthBottom:0,viewportEdgeFadeWidthLeft:0,viewportEdgeFadeDistanceTop:-1/0,viewportEdgeFadeDistanceRight:-1/0,viewportEdgeFadeDistanceBottom:-1/0,viewportEdgeFadeDistanceLeft:-1/0}),this.font=this.properties.font?e.context.fontManager.getFont(this.properties.font,this.properties.fontStyle,this.properties.fontWeight):e.context.fontManager.getDefaultFont(),this.setupExprRefsNeedingGraphicsUpdate(["text","fitToBand","logoLetters"])}getAttributes(){return["uniqueId","facetIndex","x","x2","y","y2","color","size","opacity","angle"]}getSupportedChannels(){return[...super.getSupportedChannels(),"x2","y2","size","text","angle"]}fixEncoding(e){for(const n of gi)this.properties.fitToBand&&ed(e,n);return e}async initializeGraphics(){await super.initializeGraphics(),this.createAndLinkShaders(ND,zD,[UD])}finalizeGraphicsInitialization(){super.finalizeGraphicsInitialization(),this.gl.useProgram(this.programInfo.program);const e=this.properties,n=this.font.metrics.common.base*.35*(this.properties.logoLetters?.5:1);this.registerMarkUniformValue("uPaddingX",e.paddingX),this.registerMarkUniformValue("uPaddingY",e.paddingY),this.registerMarkUniformValue("uFlushX",e.flushX,r=>!!r),this.registerMarkUniformValue("uFlushY",e.flushY,r=>!!r),this.registerMarkUniformValue("uSqueeze",e.squeeze,r=>!!r),Qs(this.markUniformInfo,{uAlign:[GD[e.align],HD[e.baseline]],uD:[e.dx,-e.dy],uLogoLetter:!!e.logoLetters,uSdfNumerator:n,uViewportEdgeFadeWidth:[e.viewportEdgeFadeWidthTop,e.viewportEdgeFadeWidthRight,e.viewportEdgeFadeWidthBottom,e.viewportEdgeFadeWidthLeft],uViewportEdgeFadeDistance:[e.viewportEdgeFadeDistanceTop,e.viewportEdgeFadeDistanceRight,e.viewportEdgeFadeDistanceBottom,e.viewportEdgeFadeDistanceLeft]})}updateGraphicsData(){const e=this.unitView.getCollector();if(!e){console.debug("No collector");return}const n=e.getData(),r=this.encoding,o=this.encoders.text;let i=0;const s="format"in r.text?Dt(r.text.format):l=>l;for(const l of n){const u=s(o(l)),f=rt(u)?u:u===null?"":""+u;i+=f&&f.length||0}const a=new uD({encoders:this.encoders,attributes:this.getAttributes(),properties:this.properties,fontMetrics:this.font.metrics,numCharacters:Math.max(i,this.properties.minBufferSize||1024)});a.addBatches(e.facetBatches);const c=a.toArrays();this.rangeMap.migrateEntries(c.rangeMap),this.updateBufferInfo(c)}prepareRender(e){const n=super.prepareRender(e);return n.push(()=>{li(this.programInfo,{uTexture:this.font.texture})}),n.push(()=>this.bindOrSetMarkUniformBlock()),n.push(()=>ui(this.gl,this.programInfo,this.vertexArrayInfo)),n}render(e){const n=this.gl;return this.createRenderCallback((r,o)=>al(n,this.vertexArrayInfo,n.TRIANGLES,o,r),e)}}const cb=1;function td(){let t=[0,1],e=[0,1],n=1,r=1,o=0,i=0,s=.5,a=0;const l=u=>(u+s-t[0])/n*r+e[0];return l.invert=u=>(u-e[0])/r*n+t[0]-s,l.domain=function(u){if(arguments.length){t=l3(u),n=t[1]-t[0];const f=t[0]===0&&t[0]===0;if(n<cb&&!f){n=cb;const d=(t[0]+t[1])/2;t[0]=d-n/2,t[1]=d+n/2}return l}else return t.slice()},l.range=function(u){return arguments.length?(e=[...u],r=e[1]-e[0],l):e},l.numberingOffset=function(u){return arguments.length?(a=u,l):a},l.padding=function(u){return arguments.length?(i=u,o=Math.min(1,u),l):o},l.paddingInner=function(u){return arguments.length?(o=Math.min(1,u),l):o},l.paddingOuter=function(u){return arguments.length?(i=u,l):i},l.align=function(u){return arguments.length?(s=Math.max(0,Math.min(1,u)),l):s},l.step=()=>r/n,l.bandwidth=()=>l.step(),l.ticks=u=>{const f=l.align(),d=l.numberingOffset();return Tc(t[0]-f+d,t[1]-f+d,Math.min(u,Math.ceil(n))).filter(Number.isInteger).map(h=>h-a)},l.tickFormat=(u,f)=>{if(f)throw new Error("Index scale's tickFormat does not support a specifier!");const h=ri(t[0],t[1],Math.min(u,Math.ceil(n)))<1e5?Dt(","):Dt(".3s");return p=>h(p+a)},l.copy=()=>td().domain(t).range(e).paddingInner(o).paddingOuter(i).numberingOffset(a),l}function jD(){const t=td().numberingOffset(1);let e;t.genome=function(r){return arguments.length?(e=r,t):e},t.ticks=r=>{if(!e)return[];const o=t.domain(),i=t.numberingOffset(),[s,a]=[Math.max(o[0],0),Math.min(o[1],e.totalSize-1)].map(u=>e.toChromosome(u)),c=Math.max(1,ri(o[0],o[1],r)),l=[];for(let u=s.index;u<=a.index;u++){const f=e.chromosomes[u],d=Math.max(f.continuousStart+c,o[0]-(o[0]-f.continuousStart)%c),h=Math.min(f.continuousEnd-c/4,o[1]+1);for(let p=d;p<=h;p+=c){const y=p-i;y>=o[0]&&y<o[1]&&l.push(y)}}return l},t.tickFormat=(r,o)=>{if(!e)return;if(o)throw new Error("Locus scale's tickFormat does not support a specifier!");const i=t.domain(),s=i[1]-i[0],a=t.numberingOffset(),l=ri(i[0],i[1],Math.min(r,Math.ceil(s)))<1e6?Dt(","):Dt(".3s"),u=f=>f-e.toChromosome(f).continuousStart;return f=>l(u(f)+a)};const n=t.copy;return t.copy=()=>n().genome(e),t}function qD(t){return t.type=="locus"}function Hl(t,e,n){if(n=n||[],t.some(s=>s===null)){if(t.every(s=>s===null))return null;throw console.warn(t),new Error("Cannot merge objects with nulls!")}const r={},o=(s,a)=>s===a||vo(s)&&vo(a)||vo(s)&&a===!0||s===!0&&Rt(a)||Array.isArray(s)&&Array.isArray(a)&&s.length===a.length&&s.every((c,l)=>c===a[l]),i=s=>{for(let a in s){const c=s[a];if(!n.includes(a)&&c!==void 0)if(r[a]!==void 0&&!o(r[a],c))console.warn(`Conflicting property ${a} of ${e}: (${JSON.stringify(r[a])} and ${JSON.stringify(s[a])}). Using ${JSON.stringify(r[a])}.`);else{const l=r[a];if(vo(l))vo(c)&&(r[a]=Hl([l,c],a));else if(vo(c)){if(!(l===!0||l===void 0))throw new Error("Bug in merge! Target is: "+l);r[a]=Hl([{},c],a)}else r[a]=c}}};for(const s of t)i(s);return r}function vo(t){return Rt(t)&&!Array.isArray(t)}/*!
+};`,xD={left:-1,center:0,right:1},AD={top:-1,middle:0,bottom:1,alphabetic:1};class wD extends No{constructor(e){super(e),this.augmentDefaultProperties({x:.5,y:.5,x2:void 0,y2:void 0,text:"",size:11,color:"black",opacity:1,font:void 0,fontStyle:void 0,fontWeight:void 0,align:"center",baseline:"middle",dx:0,dy:0,angle:0,fitToBand:!1,squeeze:!0,paddingX:0,paddingY:0,flushX:!0,flushY:!0,logoLetters:!1,viewportEdgeFadeWidthTop:0,viewportEdgeFadeWidthRight:0,viewportEdgeFadeWidthBottom:0,viewportEdgeFadeWidthLeft:0,viewportEdgeFadeDistanceTop:-1/0,viewportEdgeFadeDistanceRight:-1/0,viewportEdgeFadeDistanceBottom:-1/0,viewportEdgeFadeDistanceLeft:-1/0}),this.font=this.properties.font?e.context.fontManager.getFont(this.properties.font,this.properties.fontStyle,this.properties.fontWeight):e.context.fontManager.getDefaultFont(),this.setupExprRefsNeedingGraphicsUpdate(["text","fitToBand","logoLetters"])}getAttributes(){return["uniqueId","facetIndex","x","x2","y","y2","color","size","opacity","angle"]}getSupportedChannels(){return[...super.getSupportedChannels(),"x2","y2","size","text","angle"]}fixEncoding(e){for(const t of Dr)this.properties.fitToBand&&rh(e,t);return e}async initializeGraphics(){await super.initializeGraphics(),this.createAndLinkShaders(gD,yD,[bD])}finalizeGraphicsInitialization(){super.finalizeGraphicsInitialization(),this.gl.useProgram(this.programInfo.program);const e=this.properties,t=this.font.metrics.common.base*.35*(this.properties.logoLetters?.5:1);this.registerMarkUniformValue("uPaddingX",e.paddingX),this.registerMarkUniformValue("uPaddingY",e.paddingY),this.registerMarkUniformValue("uFlushX",e.flushX,r=>!!r),this.registerMarkUniformValue("uFlushY",e.flushY,r=>!!r),this.registerMarkUniformValue("uSqueeze",e.squeeze,r=>!!r),ao(this.markUniformInfo,{uAlign:[xD[e.align],AD[e.baseline]],uD:[e.dx,-e.dy],uLogoLetter:!!e.logoLetters,uSdfNumerator:t,uViewportEdgeFadeWidth:[e.viewportEdgeFadeWidthTop,e.viewportEdgeFadeWidthRight,e.viewportEdgeFadeWidthBottom,e.viewportEdgeFadeWidthLeft],uViewportEdgeFadeDistance:[e.viewportEdgeFadeDistanceTop,e.viewportEdgeFadeDistanceRight,e.viewportEdgeFadeDistanceBottom,e.viewportEdgeFadeDistanceLeft]})}updateGraphicsData(){const e=this.unitView.getCollector();if(!e){console.debug("No collector");return}const t=e.getData(),r=this.encoding,i=this.encoders.text;let s=0;const o="format"in r.text?Le(r.text.format):u=>u;for(const u of t){const l=o(i(u)),f=me(l)?l:l===null?"":""+l;s+=f&&f.length||0}const a=new _5({encoders:this.encoders,attributes:this.getAttributes(),properties:this.properties,fontMetrics:this.font.metrics,numCharacters:Math.max(s,this.properties.minBufferSize||1024)});a.addBatches(e.facetBatches);const c=a.toArrays();this.rangeMap.migrateEntries(c.rangeMap),this.updateBufferInfo(c)}prepareRender(e){const t=super.prepareRender(e);return t.push(()=>{Ar(this.programInfo,{uTexture:this.font.texture})}),t.push(()=>this.bindOrSetMarkUniformBlock()),t.push(()=>wr(this.gl,this.programInfo,this.vertexArrayInfo)),t}render(e){const t=this.gl;return this.createRenderCallback((r,i)=>Ac(t,this.vertexArrayInfo,t.TRIANGLES,i,r),e)}}const R1=1;function ih(){let n=[0,1],e=[0,1],t=1,r=1,i=0,s=0,o=.5,a=0;const u=l=>(l+o-n[0])/t*r+e[0];return u.invert=l=>(l-e[0])/r*t+n[0]-o,u.domain=function(l){if(arguments.length){n=VA(l),t=n[1]-n[0];const f=n[0]===0&&n[0]===0;if(t<R1&&!f){t=R1;const d=(n[0]+n[1])/2;n[0]=d-t/2,n[1]=d+t/2}return u}else return n.slice()},u.range=function(l){return arguments.length?(e=[...l],r=e[1]-e[0],u):e},u.numberingOffset=function(l){return arguments.length?(a=l,u):a},u.padding=function(l){return arguments.length?(s=l,i=Math.min(1,l),u):i},u.paddingInner=function(l){return arguments.length?(i=Math.min(1,l),u):i},u.paddingOuter=function(l){return arguments.length?(s=l,u):s},u.align=function(l){return arguments.length?(o=Math.max(0,Math.min(1,l)),u):o},u.step=()=>r/t,u.bandwidth=()=>u.step(),u.ticks=l=>{const f=u.align(),d=u.numberingOffset();return Ga(n[0]-f+d,n[1]-f+d,Math.min(l,Math.ceil(t))).filter(Number.isInteger).map(h=>h-a)},u.tickFormat=(l,f)=>{if(f)throw new Error("Index scale's tickFormat does not support a specifier!");const h=pr(n[0],n[1],Math.min(l,Math.ceil(t)))<1e5?Le(","):Le(".3s");return p=>h(p+a)},u.copy=()=>ih().domain(n).range(e).paddingInner(i).paddingOuter(s).numberingOffset(a),u}function vD(){const n=ih().numberingOffset(1);let e;n.genome=function(r){return arguments.length?(e=r,n):e},n.ticks=r=>{if(!e)return[];const i=n.domain(),s=n.numberingOffset(),[o,a]=[Math.max(i[0],0),Math.min(i[1],e.totalSize-1)].map(l=>e.toChromosome(l)),c=Math.max(1,pr(i[0],i[1],r)),u=[];for(let l=o.index;l<=a.index;l++){const f=e.chromosomes[l],d=Math.max(f.continuousStart+c,i[0]-(i[0]-f.continuousStart)%c),h=Math.min(f.continuousEnd-c/4,i[1]+1);for(let p=d;p<=h;p+=c){const m=p-s;m>=i[0]&&m<i[1]&&u.push(m)}}return u},n.tickFormat=(r,i)=>{if(!e)return;if(i)throw new Error("Locus scale's tickFormat does not support a specifier!");const s=n.domain(),o=s[1]-s[0],a=n.numberingOffset(),u=pr(s[0],s[1],Math.min(r,Math.ceil(o)))<1e6?Le(","):Le(".3s"),l=f=>f-e.toChromosome(f).continuousStart;return f=>u(l(f)+a)};const t=n.copy;return n.copy=()=>t().genome(e),n}function SD(n){return n.type=="locus"}function tu(n,e,t){if(t=t||[],n.some(o=>o===null)){if(n.every(o=>o===null))return null;throw console.warn(n),new Error("Cannot merge objects with nulls!")}const r={},i=(o,a)=>o===a||Mi(o)&&Mi(a)||Mi(o)&&a===!0||o===!0&&Ge(a)||Array.isArray(o)&&Array.isArray(a)&&o.length===a.length&&o.every((c,u)=>c===a[u]),s=o=>{for(let a in o){const c=o[a];if(!t.includes(a)&&c!==void 0)if(r[a]!==void 0&&!i(r[a],c))console.warn(`Conflicting property ${a} of ${e}: (${JSON.stringify(r[a])} and ${JSON.stringify(o[a])}). Using ${JSON.stringify(r[a])}.`);else{const u=r[a];if(Mi(u))Mi(c)&&(r[a]=tu([u,c],a));else if(Mi(c)){if(!(u===!0||u===void 0))throw new Error("Bug in merge! Target is: "+u);r[a]=tu([{},c],a)}else r[a]=c}}};for(const o of n)s(o);return r}function Mi(n){return Ge(n)&&!Array.isArray(n)}/*!
  * Adapted from vega-encode:
  * https://github.com/vega/vega/blob/master/packages/vega-encode/src/ticks.js
  *
@@ -480,7 +480,7 @@ if(scale<1.0){if(uSqueeze){vec2 scaleFadeExtent=vec2(3.0,6.0)/size;if(scale<scal
  * All rights reserved.
  *
  * BSD-3-Clause License: https://github.com/vega/vega-lite/blob/master/LICENSE
- */function lb(t,e,n){return Ht(e)&&n!=null&&(e=Math.min(e,~~(gs(t.domain())/n)||1)),Rt(e)&&(e.step,e=e.interval),e}function ub(t,e,n){var r=t.range(),o=Math.floor(r[0]),i=Math.ceil(Wn(r));if(o>i&&(r=i,i=o,o=r),e=e.filter(function(a){return a=t(a),o<=a&&a<=i}),n>0&&e.length>1){for(var s=[e[0],Wn(e)];e.length>n&&e.length>=3;)e=e.filter(function(a,c){return!(c%2)});e.length<3&&(e=s)}return e}function WD(t,e){return t.bins?ub(t,YD(t.bins,e)):t.ticks?t.ticks(e):t.domain()}function YD(t,e){var n=t.length,r=~~(n/(e||n));return r<2?t.slice():t.filter(function(o,i){return!(i%r)})}function QD(t,e,n){var r=t.tickFormat?t.tickFormat(e,n):n?Dt(n):String;if(Oy(t.type)){var o=XD(n);r=t.bins?o:ZD(r,o)}return r}function ZD(t,e){return function(n){return t(n)?e(n):""}}function XD(t){var e=Qi(t||",");if(e.precision==null){switch(e.precision=12,e.type){case"%":e.precision-=2;break;case"e":e.precision-=1;break}return KD(Dt(e),Dt(".1f")(1)[1])}else return Dt(e)}function KD(t,e){return function(n){var r=t(n),o=r.indexOf(e),i,s;if(o<0)return r;for(i=JD(r,o),s=i<r.length?r.slice(i):"";--i>o;)if(r[i]!=="0"){++i;break}return r.slice(0,i)+s}}function JD(t,e){var n=t.lastIndexOf("e"),r;if(n>0)return n;for(n=t.length;--n>e;)if(r=t.charCodeAt(n),r>=48&&r<=57)return n+1}/*!
+ */function O1(n,e,t){return Ze(e)&&t!=null&&(e=Math.min(e,~~(Ts(n.domain())/t)||1)),Ge(e)&&(e.step,e=e.interval),e}function N1(n,e,t){var r=n.range(),i=Math.floor(r[0]),s=Math.ceil(en(r));if(i>s&&(r=s,s=i,i=r),e=e.filter(function(a){return a=n(a),i<=a&&a<=s}),t>0&&e.length>1){for(var o=[e[0],en(e)];e.length>t&&e.length>=3;)e=e.filter(function(a,c){return!(c%2)});e.length<3&&(e=o)}return e}function ED(n,e){return n.bins?N1(n,CD(n.bins,e)):n.ticks?n.ticks(e):n.domain()}function CD(n,e){var t=n.length,r=~~(t/(e||t));return r<2?n.slice():n.filter(function(i,s){return!(s%r)})}function DD(n,e,t){var r=n.tickFormat?n.tickFormat(e,t):t?Le(t):String;if(u1(n.type)){var i=TD(t);r=n.bins?i:ID(r,i)}return r}function ID(n,e){return function(t){return n(t)?e(t):""}}function TD(n){var e=ai(n||",");if(e.precision==null){switch(e.precision=12,e.type){case"%":e.precision-=2;break;case"e":e.precision-=1;break}return BD(Le(e),Le(".1f")(1)[1])}else return Le(e)}function BD(n,e){return function(t){var r=n(t),i=r.indexOf(e),s,o;if(i<0)return r;for(s=kD(r,i),o=s<r.length?r.slice(s):"";--s>i;)if(r[s]!=="0"){++s;break}return r.slice(0,s)+o}}function kD(n,e){var t=n.lastIndexOf("e"),r;if(t>0)return t;for(t=n.length;--t>e;)if(r=n.charCodeAt(t),r>=48&&r<=57)return t+1}/*!
  * Adapted from vega-encode:
  * https://github.com/vega/vega/blob/master/packages/vega-encode/src/Scale.js
  *
@@ -488,7 +488,7 @@ if(scale<1.0){if(uSqueeze){vec2 scaleFadeExtent=vec2(3.0,6.0)/size;if(scale<scal
  * All rights reserved.
  *
  * BSD-3-Clause License: https://github.com/vega/vega-lite/blob/master/LICENSE
- */const $D="locus",eB="index";var tB=5;function nB(t){const e=t.type;return!t.bins&&(e===yo||e===ha||e===da)}function fb(t){return St(t)&&![Vn,eB,$D].includes(t)}function hb(t){return t||{warn:(e,...n)=>console.warn(e,...n)}}var rB=CA(["set","modified","clear","type","scheme","schemeExtent","schemeCount","domain","domainMin","domainMid","domainMax","domainRaw","domainImplicit","nice","zero","bins","range","rangeStep","round","reverse","interpolate","interpolateGamma","zoom","fp64","name"]);function db(t,e,n){n=hb(n);for(const r in t)if(!rB[r]){if(r==="padding"&&fb(e.type))continue;Rn(e[r])?e[r](t[r]):n.warn("Unsupported scale property: "+r)}fB(e,t,uB(e,t,aB(e,t,n)))}function iB(t,e){const n=oB(t),r=Ze(n);if(!r)throw new Error("Unknown scale type: "+n);const o=r();return!t.domain&&St(o.type)&&(t.domain=[0,0]),db(t,o,e),o}function oB(t){var e=t.type,n="",r;return e===Vn?Vn+"-"+yo:(sB(t)&&(r=t.rawDomain?t.rawDomain.length:t.domain?t.domain.length+ +(t.domainMid!=null):0,n=r===2?Vn+"-":r===3?bo+"-":""),(n+e||yo).toLowerCase())}function sB(t){const e=t.type;return St(e)&&e!==By&&e!==ky&&(t.scheme||t.range&&t.range.length&&t.range.every(rt))}function aB(t,e,n){if(!t.domain)return 0;n=hb(n);var r=cB(t,e.domainRaw,n);if(r>-1)return r;var o=e.domain,i=t.type,s=e.zero||e.zero===void 0&&nB(t),a,c;return o?(fb(i)&&e.padding&&o[0]!==Wn(o)&&(o=lB(i,o,e.range,e.padding,e.exponent,e.constant)),(s||e.domainMin!=null||e.domainMax!=null||e.domainMid!=null)&&(a=(o=o.slice()).length-1||1,s&&(o[0]>0&&(o[0]=0),o[a]<0&&(o[a]=0)),e.domainMin!=null&&(o[0]=e.domainMin),e.domainMax!=null&&(o[a]=e.domainMax),e.domainMid!=null&&(c=e.domainMid,(c<o[0]||c>o[a])&&n.warn("Scale domainMid exceeds domain min or max.",c),o.splice(a,0,c))),t.domain(pb(i,o,n)),i===jh&&t.unknown(e.domainImplicit?uh:void 0),e.nice&&t.nice&&t.nice(e.nice!==!0&&lb(t,e.nice)||null),o.length):0}function cB(t,e,n){return e?(t.domain(pb(t.type,e,n)),e.length):-1}function lB(t,e,n,r,o,i){n??(n=[0,1]);var s=Math.abs(Wn(n)-n[0]),a=s/(s-2*r),c=t===Fr?ip(e,null,a):t===da?Mu(e,null,a,.5):t===ha?Mu(e,null,a,o||1):t===Fl?fA(e,null,a,i||1):rp(e,null,a);return e=e.slice(),e[0]=c[0],e[e.length-1]=c[1],e}function pb(t,e,n){if(Oy(t)){var r=Math.abs(e.reduce(function(o,i){return o+(i<0?-1:i>0?1:0)},0));r!==e.length&&n.warn("Log scale domain includes zero: "+Pu(e))}return e}function uB(t,e,n){let r=e.bins;if(r&&!_t(r)){const o=(r.start==null||r.stop==null)&&t.domain(),i=r.start==null?o[0]:r.start,s=r.stop==null?Wn(o):r.stop,a=r.step;a||bn("Scale bins parameter missing step property."),r=Is(i,s+a,a)}return r?t.bins=r:t.bins&&delete t.bins,t.type===Wh&&(r?!e.domain&&!e.domainRaw&&(t.domain(r),n=r.length):t.bins=t.domain()),n}function fB(t,e,n){var r=t.type,o=e.round||!1,i=e.range;if(e.rangeStep!=null)i=hB(r,e,n);else if(e.scheme&&(i=dB(r,e,n),Rn(i))){if(t.interpolator)return t.interpolator(i);bn(`Scale type ${r} does not support interpolating color schemes.`)}if(i&&Pl(r))return t.interpolator(Ll(nd(i,e.reverse),e.interpolate,e.interpolateGamma));i&&e.interpolate&&t.interpolate?t.interpolate(Ny(e.interpolate,e.interpolateGamma)):Rn(t.round)?t.round(o):Rn(t.rangeRound)&&t.interpolate(o?ua:_r),i&&t.range(nd(i,e.reverse))}function hB(t,e,n){t!==Fy&&t!==qh&&bn("Only band and point scales support rangeStep.");var r=(e.paddingOuter!=null?e.paddingOuter:e.padding)||0,o=t===qh?1:(e.paddingInner!=null?e.paddingInner:e.padding)||0;return[0,e.rangeStep*Hh(n,o,r)]}function dB(t,e,n){var r=e.schemeExtent,o,i;return _t(e.scheme)?i=Ll(e.scheme,e.interpolate,e.interpolateGamma):(o=e.scheme.toLowerCase(),i=Qh(o),i||bn(`Unrecognized scheme name: ${e.scheme}`)),n=t===Ry?n+1:t===Wh?n-1:t===Vh||t===_y?+e.schemeCount||tB:n,Pl(t)?gb(i,r,e.reverse):Rn(i)?DT(gb(i,r),n):t===jh?i:i.slice(0,n)}function gb(t,e,n){return Rn(t)&&(e||n)?TT(t,nd(e||[0,1],n)):t}function nd(t,e){return e?t.slice().reverse():t}const mb=Dt(",d");function pB(t,e){return t.chrom+":"+mb(Math.floor(t.pos+1))+"-"+(t.chrom!=e.chrom?e.chrom+":":"")+mb(Math.ceil(e.pos))}const yb={dm6:`chr3R	32079331
+ */const FD="locus",PD="index";var MD=5;function RD(n){const e=n.type;return!n.bins&&(e===Bi||e===Do||e===Io)}function L1(n){return Oe(n)&&![qt,PD,FD].includes(n)}function z1(n){return n||{warn:(e,...t)=>console.warn(e,...t)}}var OD=iA(["set","modified","clear","type","scheme","schemeExtent","schemeCount","domain","domainMin","domainMid","domainMax","domainRaw","domainImplicit","nice","zero","bins","range","rangeStep","round","reverse","interpolate","interpolateGamma","zoom","fp64","name"]);function U1(n,e,t){t=z1(t);for(const r in n)if(!OD[r]){if(r==="padding"&&L1(e.type))continue;Nt(e[r])?e[r](n[r]):t.warn("Unsupported scale property: "+r)}_D(e,n,VD(e,n,UD(e,n,t)))}function ND(n,e){const t=LD(n),r=le(t);if(!r)throw new Error("Unknown scale type: "+t);const i=r();return!n.domain&&Oe(i.type)&&(n.domain=[0,0]),U1(n,i,e),i}function LD(n){var e=n.type,t="",r;return e===qt?qt+"-"+Bi:(zD(n)&&(r=n.rawDomain?n.rawDomain.length:n.domain?n.domain.length+ +(n.domainMid!=null):0,t=r===2?qt+"-":r===3?ki+"-":""),(t+e||Bi).toLowerCase())}function zD(n){const e=n.type;return Oe(e)&&e!==t1&&e!==n1&&(n.scheme||n.range&&n.range.length&&n.range.every(me))}function UD(n,e,t){if(!n.domain)return 0;t=z1(t);var r=GD(n,e.domainRaw,t);if(r>-1)return r;var i=e.domain,s=n.type,o=e.zero||e.zero===void 0&&RD(n),a,c;return i?(L1(s)&&e.padding&&i[0]!==en(i)&&(i=HD(s,i,e.range,e.padding,e.exponent,e.constant)),(o||e.domainMin!=null||e.domainMax!=null||e.domainMid!=null)&&(a=(i=i.slice()).length-1||1,o&&(i[0]>0&&(i[0]=0),i[a]<0&&(i[a]=0)),e.domainMin!=null&&(i[0]=e.domainMin),e.domainMax!=null&&(i[a]=e.domainMax),e.domainMid!=null&&(c=e.domainMid,(c<i[0]||c>i[a])&&t.warn("Scale domainMid exceeds domain min or max.",c),i.splice(a,0,c))),n.domain(G1(s,i,t)),s===Wf&&n.unknown(e.domainImplicit?hf:void 0),e.nice&&n.nice&&n.nice(e.nice!==!0&&O1(n,e.nice)||null),i.length):0}function GD(n,e,t){return e?(n.domain(G1(n.type,e,t)),e.length):-1}function HD(n,e,t,r,i,s){t??(t=[0,1]);var o=Math.abs(en(t)-t[0]),a=o/(o-2*r),c=n===_n?kd(e,null,a):n===Io?Nu(e,null,a,.5):n===Do?Nu(e,null,a,i||1):n===Wc?jx(e,null,a,s||1):Bd(e,null,a);return e=e.slice(),e[0]=c[0],e[e.length-1]=c[1],e}function G1(n,e,t){if(u1(n)){var r=Math.abs(e.reduce(function(i,s){return i+(s<0?-1:s>0?1:0)},0));r!==e.length&&t.warn("Log scale domain includes zero: "+Lu(e))}return e}function VD(n,e,t){let r=e.bins;if(r&&!Ue(r)){const i=(r.start==null||r.stop==null)&&n.domain(),s=r.start==null?i[0]:r.start,o=r.stop==null?en(i):r.stop,a=r.step;a||Ct("Scale bins parameter missing step property."),r=Us(s,o+a,a)}return r?n.bins=r:n.bins&&delete n.bins,n.type===Yf&&(r?!e.domain&&!e.domainRaw&&(n.domain(r),t=r.length):n.bins=n.domain()),t}function _D(n,e,t){var r=n.type,i=e.round||!1,s=e.range;if(e.rangeStep!=null)s=jD(r,e,t);else if(e.scheme&&(s=QD(r,e,t),Nt(s))){if(n.interpolator)return n.interpolator(s);Ct(`Scale type ${r} does not support interpolating color schemes.`)}if(s&&Yc(r))return n.interpolator(Xc(sh(s,e.reverse),e.interpolate,e.interpolateGamma));s&&e.interpolate&&n.interpolate?n.interpolate(l1(e.interpolate,e.interpolateGamma)):Nt(n.round)?n.round(i):Nt(n.rangeRound)&&n.interpolate(i?Eo:Hn),s&&n.range(sh(s,e.reverse))}function jD(n,e,t){n!==s1&&n!==qf&&Ct("Only band and point scales support rangeStep.");var r=(e.paddingOuter!=null?e.paddingOuter:e.padding)||0,i=n===qf?1:(e.paddingInner!=null?e.paddingInner:e.padding)||0;return[0,e.rangeStep*jf(t,i,r)]}function QD(n,e,t){var r=e.schemeExtent,i,s;return Ue(e.scheme)?s=Xc(e.scheme,e.interpolate,e.interpolateGamma):(i=e.scheme.toLowerCase(),s=Zf(i),s||Ct(`Unrecognized scheme name: ${e.scheme}`)),t=n===i1?t+1:n===Yf?t-1:n===Qf||n===r1?+e.schemeCount||MD:t,Yc(n)?H1(s,r,e.reverse):Nt(s)?a5(H1(s,r),t):n===Wf?s:s.slice(0,t)}function H1(n,e,t){return Nt(n)&&(e||t)?o5(n,sh(e||[0,1],t)):n}function sh(n,e){return e?n.slice().reverse():n}const V1=Le(",d");function WD(n,e){return n.chrom+":"+V1(Math.floor(n.pos+1))+"-"+(n.chrom!=e.chrom?e.chrom+":":"")+V1(Math.ceil(e.pos))}const _1={dm6:`chr3R	32079331
 chr3L	28110227
 chr2R	25286936
 chrX	23542271
@@ -609,12 +609,12 @@ chr18	90702639
 chr19	61431566
 chrX	171031299
 chrY	91744698
-chrM	16299`};function gB(t){if(!(t in yb))throw new Error(`Unknown assembly: ${t}`);return yb[t].split(`
-`).map(e=>{const n=e.split("	");return{name:n[0],size:parseInt(n[1])}})}const mB=/^([A-Za-z]+:)?\/\//;function Si(t,e){if(e&&mB.test(e))return e;const n=typeof t=="function"?t():t;if(!n)return e;if(!e)return n;if(/[#?]/.test(n))throw new Error(`Cannot append to a url with query or hash. Append: ${e}, base: ${n}`);return bb(n)+e}function bb(t){const e=t.replace(/[^/]*$/,"");return e===""?void 0:e.endsWith("://")?t+"/":e}class yB{constructor(e){if(this.config={name:"custom",...e},"baseUrl"in e)throw new Error("The `baseUrl` property in genome config has been removed in GenomeSpy v0.52.0. Use `url` instead. See https://genomespy.app/docs/genomic-data/genomic-coordinates/.");if(!rd(e))throw new Error("Not a genome configuration: "+JSON.stringify(e));if(this.chromosomes=[],this.cumulativeChromPositions=new Map,this.chromosomesByName=new Map,this.startByIndex=[],this.totalSize=0,xb(this.config))this.setChromSizes(this.config.contigs);else if(!id(this.config)){const n=gB(this.config.name);if(n)this.setChromSizes(n);else throw new Error(`Unknown genome: ${this.config.name}. Please provide contigs or a URL. See https://genomespy.app/docs/genomic-data/genomic-coordinates/.`)}}get name(){return this.config.name}async load(e){if(id(this.config))try{const n=Si(e,this.config.url),r=await fetch(n);if(!r.ok)throw new Error(`${r.status} ${r.statusText}`);this.setChromSizes(bB(await r.text()))}catch(n){throw new Error(`Could not load chrom sizes: ${this.config.url}. Reason: ${n.message}`)}}hasChrPrefix(){return this.chromosomes.some(e=>e.name.startsWith("chr"))}setChromSizes(e){let n=0;this.startByIndex=[0];for(let r=0;r<e.length;r++){this.startByIndex.push(n);const o=e[r].size,i={...e[r],continuousStart:n,continuousEnd:n+o,continuousInterval:[n,n+o],index:r,number:r+1,odd:!(r&1)};this.chromosomes.push(i);const s=i.name.replace(/^chr/i,"");for(const a of["chr"+s,"CHR"+s,"Chr"+s,i.number,""+i.number,s,i.name])this.cumulativeChromPositions.set(a,n),this.chromosomesByName.set(a,i);n+=i.size}this.totalSize=n}getExtent(){return[0,this.totalSize]}toContinuous(e,n){let r=this.cumulativeChromPositions.get(e);if(r===void 0)throw new Error("Unknown chromosome/contig: "+e);return r+ +n}toChromosome(e){if(e>this.totalSize)return;e=Math.floor(e);const n=mr(this.startByIndex,e)-1;if(n>0&&n<=this.chromosomes.length)return this.chromosomes[n-1]}toChromosomal(e){const n=this.toChromosome(e);if(n)return{chrom:n.name,pos:Math.floor(e)-n.continuousStart}}getChromosome(e){return this.chromosomesByName.get(e)}formatInterval(e){return pB(...this.toChromosomalInterval(e))}toChromosomalInterval(e){const n=this.toChromosomal(e[0]+.5),r=this.toChromosomal(e[1]-.5);return r.pos+=1,[n,r]}toContinuousInterval(e){var o;let[n,r]=e;return r||(r=n),[this.toContinuous(n.chrom,n.pos??0),this.toContinuous(r.chrom,r.pos??((o=this.chromosomesByName.get(r.chrom))==null?void 0:o.size))]}toDiscreteChromosomeIntervals(e){const n=e[0],r=e[1],o=[];if(n.chrom===r.chrom)o.push({chrom:n.chrom,startPos:n.pos,endPos:r.pos});else{const i=this.chromosomes.findIndex(a=>a.name===n.chrom),s=this.chromosomes.findIndex(a=>a.name===r.chrom);o.push({chrom:n.chrom,startPos:n.pos,endPos:this.chromosomes[i].size});for(let a=i+1;a<s;a++)o.push({chrom:this.chromosomes[a].name,startPos:0,endPos:this.chromosomes[a].size});o.push({chrom:r.chrom,startPos:0,endPos:r.pos})}return o}continuousToDiscreteChromosomeIntervals(e){return this.toDiscreteChromosomeIntervals([this.toChromosomal(e[0]),this.toChromosomal(e[1])])}parseInterval(e){const n=e.match(/^(chr[0-9A-Z]+)(?::([0-9,]+)(?:-(?:(chr[0-9A-Z]+):)?([0-9,]+))?)?$/);if(n){const r=n[1];if(n.slice(2).every(a=>a===void 0)){const a=this.getChromosome(r);return a?[a.continuousStart,a.continuousEnd]:void 0}const o=n[3]||r,i=parseInt(n[2].replace(/,/g,"")),s=n[4]!==void 0?parseInt(n[4].replace(/,/g,"")):i;return[this.toContinuous(r,i-1),this.toContinuous(o,s)]}}}function bB(t){return ZA(t).map(([e,n])=>({name:e,size:parseInt(n)}))}function wb(t){return Rt(t)&&"chrom"in t}function wB(t){return t.every(wb)}function rd(t){return Rt(t)&&("name"in t||id(t)||xb(t))}function id(t){return rd(t)&&"url"in t}function xb(t){return rd(t)&&"contigs"in t}class Ea extends Array{constructor(){super(),this.type=void 0}extend(e){return this}extendAll(e){if(e instanceof Ea&&e.type!=this.type)throw new Error(`Cannot combine different types of domains: ${this.type} and ${e.type}`);for(const n of e)this.extend(n);return this}extendAllWithAccessor(e,n){for(const r of e)this.extend(n(r));return this}}class od extends Ea{constructor(){super(),this.type="quantitative"}extend(e){return e==null||Number.isNaN(e)?this:(e=+e,this.length?e<this[0]?this[0]=e:e>this[1]&&(this[1]=e):(this.push(e),this.push(e)),this)}}class vb extends Ea{constructor(){super(),this.type="ordinal",this.uniqueValues=new Set}extend(e){return e==null||Number.isNaN(e)?this:(this.uniqueValues.has(e)||(this.uniqueValues.add(e),this.push(e)),this)}}class Ab extends vb{constructor(){super(),this.type="nominal"}}class xB extends Ea{constructor(e){super();let n=0;for(let r=1;r<e.length;r++)n+=Math.sign(e[r]-e[r-1]);if(Math.abs(n)!=e.length-1)throw new Error("Piecewise domain must be strictly increasing or decreasing: "+JSON.stringify(e));e.forEach(r=>this.push(r))}extend(e){if(this.includes(e))return this;throw new Error("Piecewise domains are immutable and cannot be unioned!")}}const Eb={quantitative:od,index:od,locus:od,nominal:Ab,ordinal:vb};function Sb(t,e){if(t=="quantitative"&&vB(e)){const n=new xB(e);return n.type=t,n}else if(Eb[t]){const n=new Eb[t];return n.type=t,e&&n.extendAll(e),n}throw new Error("Unknown type: "+t)}function vB(t){return t&&t.length>0&&t.length!=2&&t.every(e=>typeof e=="number")}function AB(t){return((t*=2)<=1?t*t*t:(t-=2)*t*t+2)/2}function EB(t,e,n){return t*Math.pow(e/t,n)}Ze("index",td,["continuous"]),Ze("locus",jD,["continuous"]),Ze("null",Zh,[]);const Cb="quantitative",Ib="ordinal",Tb="nominal",Db="locus",SB="index";class CB{constructor(e){he(this,Pe);he(this,Qo,{domain:new Set,range:new Set});he(this,Kt);he(this,Li);he(this,qa,new Set);this.channel=e,this.members=[],this.type=null,this.name=void 0}get zoomExtent(){return(j(this,Kt)&&St(j(this,Kt).type)&&pe(this,Pe,Vv).call(this))??[-1/0,1/0]}addEventListener(e,n){j(this,Qo)[e].add(n)}removeEventListener(e,n){j(this,Qo)[e].delete(n)}addMember(e){var a;const{channel:n,channelDef:r}=e,o=r.type==null&&this.type;if(n!="sample"&&!r.type&&!ah(n)&&!o)throw new Error(`The "type" property must be defined in channel definition: "${n}": ${JSON.stringify(r)}. Must be one of: "quantitative", "ordinal", "nominal", "locus", "index"`);const i=n=="sample"?"nominal":r.type,s=(a=r==null?void 0:r.scale)==null?void 0:a.name;if(s){if(this.name!==void 0&&s!=this.name)throw new Error(`Shared scales have conflicting names: "${s}" vs. "${this.name}"!`);this.name=s}if(!o){if(!this.type)this.type=i;else if(i!==this.type&&!ah(n))throw new Error(`Can not use shared scale for different data types: ${this.type} vs. ${i}. Use "resolve: independent" for channel ${this.channel}`)}this.members.push(e)}getDataDomain(){return this.members.map(e=>{var n;return(n=e.dataDomainSource)==null?void 0:n.call(e,e.channel,this.type)}).filter(e=>!!e).reduce((e,n)=>e.extendAll(n))}reconfigure(){const e=j(this,Kt);if(!e||e.type=="null")return;const n=pe(this,Pe,Gv).call(this),r=e.domain(),o=pe(this,Pe,G0).call(this,!0);if(db({...o,range:void 0},e),e.props=o,pe(this,Pe,H0).call(this),!j(this,Li)&&St(e.type)){const s=e.domain();gs(s)>0&&Ae(this,Li,s)}if(!n){Ae(this,Li,e.domain()),pe(this,Pe,dr).call(this,"domain");return}const i=e.domain();Uc(i,r)||(this.isZoomable()?e.domain(r):pe(this,Pe,Hi).call(this)?(e.domain(r),this.zoomTo(i,500)):pe(this,Pe,dr).call(this,"domain"))}get scale(){if(j(this,Kt))return j(this,Kt);const e=pe(this,Pe,G0).call(this),n=iB({...e,range:void 0});n.props=e,"unknown"in n&&n.unknown(null),Ae(this,Kt,n),pe(this,Pe,H0).call(this),qD(n)&&n.genome(this.getGenome());const r=n.range;if(r){const o=()=>pe(this,Pe,dr).call(this,"range");n.range=function(i){if(arguments.length)r(i),o();else return r()},o()}return n}getDomain(){return this.scale.domain()}getComplexDomain(){var e;return((e=this.getGenome())==null?void 0:e.toChromosomalInterval(this.getDomain()))??this.getDomain()}isZoomed(){return pe(this,Pe,Hi).call(this)&&Uc(pe(this,Pe,Bu).call(this),this.getDomain())}isZoomable(){return pe(this,Pe,Hi).call(this)&&!!this.scale.props.zoom}zoom(e,n,r){if(!pe(this,Pe,Hi).call(this))return!1;const o=this.scale,i=o.domain();let s=[...i],a=o.invert(n);switch(o.props.reverse&&(r=-r),"align"in o&&(a+=o.align()),o.type){case"linear":case"index":case"locus":s=cA(s,r||0),s=rp(s,a,e);break;case"log":s=lA(s,r||0),s=ip(s,a,e);break;case"pow":case"sqrt":{const l=o;s=uA(s,r||0,l.exponent()),s=Mu(s,a,e,l.exponent());break}default:throw new Error("Zooming is not implemented for: "+o.type)}const c=this.zoomExtent;return s=hA(s,c[0],c[1]),[0,1].some(l=>s[l]!=i[l])?(o.domain(s),pe(this,Pe,dr).call(this,"domain"),!0):!1}async zoomTo(e,n=!1){if(ps(n)&&(n=n?700:0),!pe(this,Pe,Hi).call(this))throw new Error("Not a zoomable scale!");const r=this.fromComplexInterval(e),o=j(this,Pe,z0).animator,i=this.scale,s=i.domain();if(n>0&&s.length==2){const a=s[1]-s[0],c=r[1]-r[0],l=s[0]+a/2,u=r[0]+c/2,f=s[0]==r[0],d=s[1]==r[1];await o.transition({duration:n,easingFunction:AB,onUpdate:h=>{const p=EB(a,c,h),y=a==c?h:(a-p)/(a-c),v=y*u+(1-y)*l,b=[f?s[0]:v-p/2,d?s[1]:v+p/2];i.domain(b),pe(this,Pe,dr).call(this,"domain")}}),i.domain(r),pe(this,Pe,dr).call(this,"domain")}else i.domain(r),o==null||o.requestRender(),pe(this,Pe,dr).call(this,"domain")}resetZoom(){if(!pe(this,Pe,Hi).call(this))throw new Error("Not a zoomable scale!");const e=this.getDomain(),n=pe(this,Pe,Bu).call(this);return[0,1].some(r=>n[r]!=e[r])?(j(this,Kt).domain(n),pe(this,Pe,dr).call(this,"domain"),!0):!1}getZoomLevel(){return this.isZoomable()?gs(this.zoomExtent)/gs(this.scale.domain()):1}getAxisLength(){if(this.channel!=="x"&&this.channel!=="y")throw new Error("Axis length is only defined for x and y channels!");const e=this.members.map(n=>{var r;return(r=n.view.coords)==null?void 0:r[this.channel==="x"?"width":"height"]}).filter(n=>n>0);return e.length?e.reduce((n,r)=>Math.min(n,r),1e4):0}getGenome(){var n;if(this.type!=="locus")return;const e=(n=j(this,Pe,z0).genomeStore)==null?void 0:n.getGenome();if(!e)throw new Error("No genome has been defined!");return e}invertToComplex(e){const n=this.scale;if("invert"in n){const r=n.invert(e);return this.toComplex(r)}else throw new Error("The scale does not support inverting!")}toComplex(e){const n=this.getGenome();return n?n.toChromosomal(e):e}fromComplex(e){return wb(e)?this.getGenome().toContinuous(e.chrom,e.pos):e}fromComplexInterval(e){return this.type==="locus"&&wB(e)?this.getGenome().toContinuousInterval(e):e}}Qo=new WeakMap,Kt=new WeakMap,Li=new WeakMap,qa=new WeakMap,Pe=new WeakSet,N0=function(){return this.members[0].view},z0=function(){return j(this,Pe,N0).context},dr=function(e){for(const n of j(this,Qo)[e].values())n({type:e,scaleResolution:this})},U0=function(){return!!pe(this,Pe,V0).call(this)},Gv=function(){const e=j(this,Kt);if(!e)return!1;const n=e.domain();return St(e.type)?n.length>2||n.length==2&&(n[0]!==0||n[1]!==0):n.length>0},Hv=function(){const e=this.members.map(n=>n.channelDef.scale).filter(n=>n!==void 0);return Hl(e,"scale",["domain"])},G0=function(e=!1){const n=pe(this,Pe,Hv).call(this);if(n===null||n.type=="null")return{type:"null"};const r={...pe(this,Pe,jv).call(this,this.type),...n};r.type||(r.type=IB(this.channel,this.type));const o=pe(this,Pe,Bu).call(this,e);return o&&o.length>0?r.domain=o:Mr(r.type)&&(r.domain=new Ab),!r.domain&&r.domainMid!==void 0&&(r.domain=[r.domainMin??0,r.domainMax??1]),this.channel=="y"&&Mr(r.type)&&r.reverse==null&&(r.reverse=!0),r.range&&r.scheme&&delete r.scheme,!("zoom"in r)&&["index","locus"].includes(r.type)&&(r.zoom=!0),TB(r,this.channel),r},H0=function(){const e=j(this,Kt).props,n=e.range;if(j(this,qa).forEach(o=>o.invalidate()),!n||!_t(n))return;const r=(o,i)=>i?o.slice().reverse():o;if(n.some(Ot)){let o;const i=()=>{j(this,Kt).range(r(o.map(s=>s()),e.reverse))};o=n.map(s=>{if(Ot(s)){const a=j(this,Pe,N0).paramMediator.createExpression(s.expr);return a.addListener(i),j(this,qa).add(a),()=>a(null)}else return()=>s}),i()}else j(this,Kt).range(r(n,e.reverse))},Bu=function(e=!1){return pe(this,Pe,V0).call(this)??(this.type==Db?this.getGenome().getExtent():e?this.getDataDomain():[])},V0=function(){const e=this.members.map(n=>n.channelDef).filter(n=>{var r;return(r=n.scale)==null?void 0:r.domain}).map(n=>Sb(n.type,this.fromComplexInterval(n.scale.domain)));if(e.length>0)return e.reduce((n,r)=>n.extendAll(r))},Hi=function(){const e=this.scale.type;return St(e)},Vv=function(){const e=this.scale.props,n=e.zoom;return DB(n)&&_t(n.extent)?this.fromComplexInterval(n.extent):n&&e.type=="locus"?this.getGenome().getExtent():j(this,Li)},jv=function(e){const n=this.channel,r={};return pe(this,Pe,U0).call(this)&&(r.zero=!1),sa(n)?r.nice=!pe(this,Pe,U0).call(this):Tr(n)?r.scheme=e==Tb?"tableau10":e==Ib?"blues":"viridis":wl(n)?r.range=n=="shape"?["circle","square","triangle-up","cross","diamond"]:[]:n=="size"?r.range=[0,400]:n=="angle"&&(r.range=[0,360]),r};function IB(t,e){if(e==SB||e==Db){if(sh(t))return e;throw new Error(`${t} does not support ${e} data type. Only positional channels do.`)}const n={x:["band","band","linear"],y:["band","band","linear"],size:[void 0,"point","linear"],opacity:[void 0,"point","linear"],fillOpacity:[void 0,"point","linear"],strokeOpacity:[void 0,"point","linear"],color:["ordinal","ordinal","linear"],fill:["ordinal","ordinal","linear"],stroke:["ordinal","ordinal","linear"],strokeWidth:[void 0,void 0,"linear"],shape:["ordinal","ordinal",void 0],dx:[void 0,void 0,"null"],dy:[void 0,void 0,"null"],angle:[void 0,void 0,"linear"],sample:["null",void 0,void 0]},o=["sample"].includes(t)?"null":n[t]?n[t][[Tb,Ib,Cb].indexOf(e)]:e==Cb?"linear":"ordinal";if(o===void 0)throw new Error(`Channel "${t}" is not compatible with "${e}" data type. Use of a proper scale may be needed.`);return o}function TB(t,e){sa(e)&&t.type!=="ordinal"&&(t.range=[0,1]),e=="opacity"&&St(t.type)&&(t.clamp=!0)}function DB(t){return Rt(t)}function sd(t){const e=new Set;function n(r){for(const o of Object.values(r.resolutions.scale))e.add(o)}for(const r of Ft(t)){r.visit(n);for(const o of r.getDataAncestors()){if(!o.options.contributesToScaleDomain)break;n(o)}}e.forEach(r=>r.reconfigure())}function ad(...t){for(const e of t)if(e!==void 0)return e}class BB{constructor(e){this.channel=e,this.members=[]}get scaleResolution(){var e;return(e=Gs(this.members))==null?void 0:e.view.getScaleResolution(this.channel)}addMember(e){const{view:n}=e,r=n.getScaleResolution(this.channel);if(!r)throw new Error("Cannot find a scale resolution!");if(this.scaleResolution&&r!==this.scaleResolution)throw new Error(`Shared axes must have a shared scale! Channel: ${this.channel}, existing views: [${this.members.map(o=>o.view.getPathString()).join(", ")}], new view: ${n.getPathString()}.`);this.members.push(e)}getAxisProps(){return zl(this,"axisProps",()=>{const e=this.members.map(n=>{const r=n.view.mark.encoding[n.channel];return"axis"in r&&r.axis});return e.length>0&&e.some(n=>n===null)?null:Hl(e.filter(n=>n!==void 0),"axis",["title"])})}getTitle(){const e=i=>{var a;const s=V5(i.view,i.channel);if(!ln(s))return{member:i,explicitTitle:ad("axis"in s?(a=s.axis)==null?void 0:a.title:void 0,s.title),implicitTitle:ad(Ir(s)?s.field:void 0,oa(s)?s.expr:void 0)}},n=this.members.map(e),r=n.filter(i=>{var s;if(ah(i.member.channel)&&!i.explicitTitle){const a=mi(i.member.channel);return((s=n.find(c=>c.member.view==i.member.view&&c.member.channel==a))==null?void 0:s.explicitTitle)===void 0}return!0}),o=new Set(r.map(i=>ad(i.explicitTitle,i.implicitTitle)).filter(rt));return o.size?[...o].join(", "):null}}function Bb(t,e,{spacing:n,devicePixelRatio:r,offset:o,reverse:i}={}){n=n||0,o=o||0;let s=0,a=0;for(const p of t)s+=Vl(p.px)+(cd(p)?0:n),a+=Vl(p.grow);s-=n;const c=Math.max(0,e-s),l=r!==void 0?p=>Math.round(p*r)/r:p=>p,u=[],f=[],d=p=>{const y=u.length;if(!y)return;const v=(p?n:0)*(i?-1:1);h-=v;for(let b=0;b<y;b++)f.push({location:h+(b+1)/(y+1)*v,size:0});h+=v,u.length=0};let h=i?Math.max(e,s):0+o;if(t.length==1&&cd(t[0]))return[{location:h,size:0}];for(let p=0;p<t.length;p++){const y=t[p];if(cd(y))u.push(y);else{d(f.length>0);const v=Vl(y.px)+(a?Vl(y.grow)/a*c:0);i&&(h-=v),f.push({location:l(h),size:l(v)}),i?h-=n:h+=v+n}}return h+=i?n:-n,d(!1),f}function kB(t){let e=0,n=0;for(const r of t)e=Math.max(e,r.px??0),n=Math.max(n,r.grow??0);return{px:e,grow:n}}const R0=class R0{constructor(e,n){he(this,Wa);this.width=e,this.height=n}addPadding(e){return pe(this,Wa,j0).call(this,e.width,e.height)}subtractPadding(e){return pe(this,Wa,j0).call(this,-e.width,-e.height)}isGrowing(){return!!(this.width.grow||this.height.grow)}};Wa=new WeakSet,j0=function(e,n){return new R0({px:(this.width.px??0)+e,grow:this.width.grow},{px:(this.height.px??0)+n,grow:this.height.grow})};let Lr=R0;const Sa=Object.freeze({px:0,grow:0}),kb=new Lr(Sa,Sa);function cd(t){return!t.px&&!t.grow}function Vl(t){return t||0}function _B(t){return t&&(Ht(t.px)||Ht(t.grow))}function _b(t){if(Mb(t))throw new Error("parseSizeDef does not accept step-based sizes.");if(_B(t))return t;if(Ht(t))return{px:t,grow:0};if(t==="container")return{px:0,grow:1};if(!t)return{px:0,grow:1};throw new Error(`Invalid sizeDef: ${t}`)}class Nt{constructor(e,n,r,o){this.top=e||0,this.right=n||0,this.bottom=r||0,this.left=o||0}get width(){return this.left+this.right}get height(){return this.top+this.bottom}expand(e){return e<=0?this:new Nt(this.top+e,this.right+e,this.bottom+e,this.left+e)}add(e){return new Nt(this.top+e.top,this.right+e.right,this.bottom+e.bottom,this.left+e.left)}subtract(e){return new Nt(this.top-e.top,this.right-e.right,this.bottom-e.bottom,this.left-e.left)}union(e){return new Nt(Math.max(this.top,e.top),Math.max(this.right,e.right),Math.max(this.bottom,e.bottom),Math.max(this.left,e.left))}getHorizontal(){return new Nt(0,this.right,0,this.left)}getVertical(){return new Nt(this.top,0,this.bottom,0)}get horizontalTotal(){return this.left+this.right}get verticalTotal(){return this.top+this.bottom}static createFromConfig(e){return typeof e=="number"?this.createUniformPadding(e):e?this.createFromRecord(e):ld}static createFromRecord(e){return new Nt(e.top,e.right,e.bottom,e.left)}static zero(){return ld}static createUniformPadding(e){return new Nt(e,e,e,e)}}const ld=Nt.createUniformPadding(0);Object.freeze(ld);function Ca(t,e){return!e||/^(data:|([A-Za-z]+:)?\/\/)/.test(t)||t.startsWith("/")?t:(e.endsWith("/")||(e+="/"),e+t)}function RB(t){if(!t)return t;if(/[?#]/.test(t))throw new Error(`Invalid base URL: ${t} - cannot contain query or hash.`);return t.endsWith("/")?t:t+"/"}const FB="VISIT_SKIP",Ia="VISIT_STOP",Rb=t=>t;class Fb{constructor(e,n,r,o,i,s={}){he(this,qn);he(this,Zo,{});he(this,Xo,{});he(this,Ko,{});he(this,Ya);he(this,Qa);Gt(this,"opacityFunction",Rb);Gt(this,"facetCoords",new Yn([],JSON.stringify));var a;if(!e)throw new Error("View spec must be defined!");if(this.context=n,this.layoutParent=r,this.dataParent=o,this.name=e.name||i,this.spec=e,this.resolutions={scale:{},axis:{}},tb(this),this.options={blockEncodingInheritance:!1,contributesToScaleDomain:!0,...s},this.needsAxes={x:!1,y:!1},this.paramMediator=new M5(()=>{var c;return(c=this.dataParent)==null?void 0:c.paramMediator}),e.params)for(const c of e.params)this.paramMediator.registerParam(c);if(!((a=this.layoutParent)!=null&&a.options.layeredChildren)){const c=l=>this.paramMediator.findMediatorForParam(l)?void 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this.visit(n=>{e.push(n)}),e}configureViewOpacity(){(!this.opacityFunction||this.opacityFunction===Rb)&&(this.opacityFunction=PB(this))}onBeforeRender(){}render(e,n,r={}){var o,i;r.firstFacet&&this.facetCoords.clear(),this.facetCoords.set(r.facetId,r.clipRect?n.intersect(r.clipRect):n),(o=j(this,Ya))==null||o.call(this,n.width),(i=j(this,Qa))==null||i.call(this,n.height)}getEncoding(){const e=this.dataParent&&!this.options.blockEncodingInheritance?this.dataParent.getEncoding():{},n=this.spec.encoding||{},r={...e,...n};for(const[o,i]of Object.entries(r))i===null&&delete r[o];return r}getFacetAccessor(e){if(this.layoutParent)return this.layoutParent.getFacetAccessor(this)}getFacetFields(e){var r;const n=this.getEncoding().sample;return Ir(n)?[n.field]:(r=this.layoutParent)==null?void 0:r.getFacetFields(this)}getSampleFacetTexture(){}getScaleResolution(e){const n=mi(e);return this.getDataAncestors().map(r=>r.resolutions.scale[n]).find(r=>r)}getAxisResolution(e){const n=mi(e);return this.getDataAncestors().map(r=>r.resolutions.axis[n]).find(r=>r)}getConfiguredResolution(e,n){var r,o;return(o=(r=this.spec.resolve)==null?void 0:r[n])==null?void 0:o[e]}getConfiguredOrDefaultResolution(e,n){return this.getConfiguredResolution(e,n)??this.getConfiguredResolution("default",n)??this.getDefaultResolution(e,n)}getDefaultResolution(e,n){return"independent"}getBaseUrl(){return Si(()=>{var e;return(e=this.dataParent)==null?void 0:e.getBaseUrl()},RB(this.spec.baseUrl))}isPickingSupported(){return!0}getTitleText(){const e=this.spec.title;if(e)return rt(e)?e:Ot(e.text)?this.paramMediator.evaluateAndGet(e.text.expr):e.text}_cache(e,n){return zl(this,e,n)}_invalidateCacheByPrefix(e,n="self"){switch(n){case"self":Ul(this,e);break;case"ancestors":for(const r of this.getLayoutAncestors())Ul(r,e);break;case"progeny":this.visit(r=>Ul(r,e));break}}invalidateSizeCache(){this._invalidateCacheByPrefix("size/","ancestors")}propagateInteractionEvent(e){}}Zo=new WeakMap,Xo=new WeakMap,Ko=new WeakMap,Ya=new WeakMap,Qa=new WeakMap,qn=new WeakSet,pc=function(e){var o;let n=this.spec[e];const r=e=="viewportWidth"||e=="viewportHeight";if(Mb(n)){if(r)throw new Pr(`Cannot use step-based size with "${e}"!`,this);const i=n.step,s=(o=this.getScaleResolution(e=="width"?"x":"y"))==null?void 0:o.scale;if(s){let a=0;if(Mr(s.type))a=s.domain().length;else if(["locus","index"].includes(s.type)){const l=s.domain();a=Gs(l)-l[0]}else throw new Pr(`Cannot use step-based size with "${s.type}" scale!`,this);const c=s;return a=Hh(a,c.paddingInner(),c.paddingOuter()),{px:a*i,grow:0}}else throw new Pr("Cannot use 'step' size with missing scale!",this)}else return(n&&_b(n))??(r?void 0:{px:0,grow:1})},q0=function(e){const n=[];let r=this;do n.push(r),r=r[e];while(r);return n};function MB(t){return"unitsPerPixel"in t}function PB(t){const e="opacity"in t.spec?t.spec.opacity:void 0;if(e!==void 0){if(Ht(e))return n=>n*e;if(MB(e)){const n=i=>{var a;const s=(a=t.getScaleResolution(i))==null?void 0:a.scale;if(["linear","index","locus"].includes(s==null?void 0:s.type))return s},r=e.channel?n(e.channel):n("x")??n("y");if(!r)throw new Pr("Cannot find a resolved quantitative scale for dynamic opacity!",t);const o=Fh().domain(e.unitsPerPixel).range(e.values).clamp(!0);return i=>{const a=gs(r.domain())/1e3;return o(a)*i}}else if(Ot(e)){const n=t.paramMediator.createExpression(e.expr);return n.addListener(()=>t.context.animator.requestRender()),r=>n(null)*r}}return n=>n}const Mb=t=>!!(t!=null&&t.step),LB={point:ID,rect:xD,rule:kD,link:OD,text:VD};class en extends Fb{constructor(n,r,o,i,s,a){super(n,r,o,i,s,a);he(this,Su);he(this,Za);this.spec=n;const c=LB[this.getMarkType()];if(c)this.mark=new c(this);else throw new Error(`No such mark: ${this.getMarkType()}`);this.resolve(),Ae(this,Za,this.paramMediator.allocateSetter("zoomLevel",1)),["x","y"].forEach(l=>{var u;return(u=this.getScaleResolution(l))==null?void 0:u.addEventListener("domain",()=>j(this,Za).call(this,Math.sqrt(this.getZoomLevel())))}),this.needsAxes={x:!0,y:!0},pe(this,Su,qv).call(this)}render(n,r,o={}){super.render(n,r,o),this.isConfiguredVisible()&&(n.pushView(this,r),n.renderMark(this.mark,o),n.popView(this))}getMarkType(){return typeof this.spec.mark=="object"?this.spec.mark.type:this.spec.mark}getEncoding(){const n=super.getEncoding(),r=this.mark.getSupportedChannels();for(const o of Object.keys(n))r.includes(o)||delete n[o];return n}resolve(n){if(!n){this.resolve("scale"),this.resolve("axis");return}const r=this.mark.encoding;for(const[o,i]of Object.entries(r)){if(!i)continue;let s;if($t(i))s=i;else if(oh(i)){const l=i.condition;if(!Array.isArray(l)&&$t(l))s=l;else continue}else continue;const a=mi(s.resolutionChannel??o);if(!xl(a)||n=="axis"&&!sa(a))continue;let c=this;for(;(c.getConfiguredOrDefaultResolution(a,n)=="forced"||c.dataParent&&["shared","excluded","forced"].includes(c.dataParent.getConfiguredOrDefaultResolution(a,n)))&&c.getConfiguredOrDefaultResolution(a,n)!="excluded";)c=c.dataParent;if(n=="axis"&&sa(o)&&sh(a))c.resolutions[n][a]||(c.resolutions[n][a]=new BB(a)),c.resolutions[n][a].addMember({view:this,channel:o,channelDef:s});else if(n=="scale"&&xl(o)){if(!c.resolutions[n][a]){const u=new CB(a);c.resolutions[n][a]=u,u.addEventListener("range",f=>{var d;(d=this.context.glHelper)==null||d.createRangeTexture(f.scaleResolution,!0)})}const l=this.getLayoutAncestors().some(u=>!u.options.contributesToScaleDomain)||$t(s)&&s.contributesToScaleDomain===!1?void 0:this.extractDataDomain.bind(this);c.resolutions[n][a].addMember({view:this,channel:o,channelDef:s,dataDomainSource:l})}}}getDataAccessor(n){var r;return(r=this.mark.encoders[n])==null?void 0:r.dataAccessor}getFacetAccessor(n){const r=this.getDataAccessor("sample");return r||super.getFacetAccessor(this)}getCollector(){return this.context.dataFlow.findCollectorByKey(this)}extractDataDomain(n,r){var i;let o=Sb(r);return(((i=this.mark.encoders[n])==null?void 0:i.accessors)??[]).filter(s=>s.scaleChannel).forEach(s=>{if(s.constant)o.extend(s({}));else{const a=this.getCollector();a!=null&&a.completed&&a.visitData(c=>o.extend(s(c)))}}),o}getZoomLevel(){const n=r=>{var o;return((o=this.getScaleResolution(r))==null?void 0:o.getZoomLevel())??1};return gi.map(n).reduce((r,o)=>r*o,1)}propagateInteractionEvent(n){this.handleInteractionEvent(void 0,n,!0),n.target=this,!n.stopped&&this.handleInteractionEvent(void 0,n,!1)}getDefaultResolution(n,r){return n=="x"?"shared":"independent"}}Za=new WeakMap,Su=new WeakSet,qv=function(){for(const[n,r]of this.paramMediator.paramConfigs){if(!("select"in r))continue;const o=yl(r.select),i=o.on,s=o.clear;if(bl(o)){let c=0;const l=this.paramMediator.getSetter(n),u=()=>{var p;const h=this.context.getCurrentHover();return((p=h==null?void 0:h.mark)==null?void 0:p.unitView)===this?h.datum:null},f=i.filter?o1(i.filter):()=>!0,d=(h,p)=>{if(!f(p.proxiedMouseEvent))return;const y=u(),v=y?y[sn]:0;let b;if(o.toggle)if(p.mouseEvent.shiftKey){if(y){const S=this.paramMediator.getValue(n);b=L5(S,{toggle:[y]})}}else b=rh(y?[y]:null);else v!=c&&(c=v,b=nh(y));b!==void 0&&l(b)};if(this.addInteractionEventListener(["mouseover","pointerover"].includes(i.type)?"mousemove":i.type,d),s){const h=s.filter?o1(s.filter):()=>!0,p=(y,v)=>{if(!h(v.proxiedMouseEvent))return;c=0;const b=o.toggle?rh():nh(null);l(b)};this.addInteractionEventListener(s.type,p)}}}};function*ud(t,e=[]){for(const[n,r]of t.entries())if(r instanceof Map)for(const o of ud(r,[...e,n]))yield o;else yield[[...e,n],r]}const Pb=2147483647,OB=Lb([Pb]);function Lb(t){let e=0;for(let n=0,r=t.length;n<r;n++)e=Math.max(e,t[n]);return Math.floor(Math.log2(e)/4)+1}function NB(t){const e=Lb(t);let n=Array.from({length:t.length},(i,s)=>s),r=new Array(t.length);const o=new Array(16);for(let i=0;i<e;i++){o.fill(0);const s=i*4,a=Math.pow(16,i),c=l=>{const u=t[n[l]];return i>=OB?u>Pb?Math.floor(u/a)%16:0:u>>s&15};for(let l=0;l<t.length;l++)o[c(l)]++;for(let l=1;l<16;l++)o[l]+=o[l-1];for(let l=t.length-1;l>=0;l--)r[--o[c(l)]]=n[l];[n,r]=[r,n]}return n}class Ob extends Wf{constructor(n){var r;super();he(this,tn);he(this,ar,[]);he(this,Xa,Qe(sn));he(this,Vr,[]);he(this,Oi);he(this,Jo);this.params=n??{type:"collect"},this.observers=[],this.facetBatches=new Yn([],JSON.stringify),Ae(this,Jo,UB((r=this.params)==null?void 0:r.sort)),pe(this,tn,W0).call(this)}get behavior(){return qf}get label(){return"collect"}reset(){super.reset(),pe(this,tn,W0).call(this)}handle(n){j(this,ar).push(n)}beginBatch(n){f8(n)&&(Ae(this,ar,[]),this.facetBatches.set(Ft(n.facetId),j(this,ar)))}complete(){var n;if(Ae(this,ar,[]),(n=this.params.groupby)!=null&&n.length){if(this.facetBatches.size>1)throw new Error("TODO: Support faceted data!");const r=this.facetBatches.get(void 0),o=this.params.groupby.map(s=>Qe(s)),i=o.length>1?Cc(r,...o):zB(r,o[0]);this.facetBatches.clear();for(const[s,a]of ud(i))this.facetBatches.set(s,a)}if(j(this,Jo))for(const r of this.facetBatches.values())r.sort(j(this,Jo));pe(this,tn,Wv).call(this),pe(this,tn,Y0).call(this),super.complete();for(const r of this.observers)r(this)}repropagate(){for(const n of this.children)n.reset();pe(this,tn,Y0).call(this);for(const n of this.children)n.complete()}getData(){switch(pe(this,tn,Q0).call(this),this.facetBatches.size){case 0:return[];case 1:return[...this.facetBatches.values()][0];default:{const n=this.facetBatches;return{[Symbol.iterator]:function*(){for(const o of n.values())yield*o}}}}}visitData(n){pe(this,tn,Q0).call(this);for(const r of this.facetBatches.values())for(let o=0;o<r.length;o++)n(r[o])}getItemCount(){let n=0;for(const r of this.facetBatches.values())n+=r.length;return n}findDatumByUniqueId(n){if(!j(this,Vr).length)return;const r=ni(c=>c.start).right,o=j(this,Xa),i=ni(c=>o(s(c))).left,s=c=>{const l=r(j(this,Oi),c),u=j(this,Oi)[l-1];return!u||c>=u.stop?void 0:this.facetBatches.get(u.facetId)[c-u.start]},a=i(j(this,Vr),n);if(a>=0){const c=s(j(this,Vr)[a]);if(c&&o(c)===n)return c}}}ar=new WeakMap,Xa=new WeakMap,Vr=new WeakMap,Oi=new WeakMap,Jo=new WeakMap,tn=new WeakSet,W0=function(){Ae(this,ar,[]),Ae(this,Vr,[]),this.facetBatches.clear(),this.facetBatches.set(void 0,j(this,ar))},Y0=function(){if(this.children.length)for(const[n,r]of this.facetBatches.entries()){if(n){const o={type:"facet",facetId:n};for(const i of this.children)i.beginBatch(o)}for(let o=0,i=r.length;o<i;o++)this._propagate(r[o])}},Q0=function(){if(!this.completed)throw new Error("Data propagation is not completed! No data are available.")},Wv=function(){var s;Ae(this,Oi,[]);const n=(s=this.facetBatches.values().next().value)==null?void 0:s[0];if(n==null||!(sn in n))return;let r=0;const o=[],i=j(this,Xa);for(const[a,c]of this.facetBatches){j(this,Oi).push({start:r,stop:r+c.length,facetId:a}),r+=c.length;for(let l=0,u=c.length;l<u;l++)o.push(i(c[l]))}Ae(this,Vr,NB(o))};function zB(t,e){const n=new Map;for(let r=0,o=t.length;r<o;r++){const i=t[r],s=e(i);let a=n.get(s);a||(a=[],n.set(s,a)),a.push(i)}return n}function UB(t){if(t!=null&&t.field){const e=Ft(t.field);if(e.length==1&&!e[0].includes(".")){const n=Ft(t.order)[0]??"ascending",r=JSON.stringify(e[0]);return new Function("a","b",`return a[${r}] ${n==="ascending"?"-":"+"} b[${r}];`)}return sp(t.field,t.order)}}class jl{constructor(){this.ids=[],this.values=[],this.length=0}clear(){this.length=0}push(e,n){let r=this.length++;for(;r>0;){const o=r-1>>1,i=this.values[o];if(n>=i)break;this.ids[r]=this.ids[o],this.values[r]=i,r=o}this.ids[r]=e,this.values[r]=n}pop(){if(this.length===0)return;const e=this.ids[0];if(this.length--,this.length>0){const n=this.ids[0]=this.ids[this.length],r=this.values[0]=this.values[this.length],o=this.length>>1;let i=0;for(;i<o;){let s=(i<<1)+1;const a=s+1;let c=this.ids[s],l=this.values[s];const u=this.values[a];if(a<this.length&&u<l&&(s=a,c=this.ids[a],l=u),l>=r)break;this.ids[i]=c,this.values[i]=l,i=s}this.ids[i]=n,this.values[i]=r}return e}peek(){if(this.length!==0)return this.ids[0]}peekValue(){if(this.length!==0)return this.values[0]}shrink(){this.ids.length=this.values.length=this.length}}class GB extends yt{get behavior(){return On}constructor(e){super(e),this.params=e,this.startAccessor=Qe(e.start),this.endAccessor=Qe(e.end),this.chromAccessor=e.chrom?Qe(e.chrom):n=>{},this.weightAccessor=e.weight?Qe(e.weight):n=>1,this.as={coverage:e.as??"coverage",start:e.asStart??e.start,end:e.asEnd??e.end,chrom:e.asChrom??e.chrom},this.createSegment=new Function("start","end","coverage","chrom","return {"+Object.entries(this.as).filter(([n,r])=>r).map(([n,r])=>`${JSON.stringify(r)}: ${n}`).join(", ")+"};"),this.ends=new jl}reset(){super.reset(),this.initialize()}initialize(){const e=this.as.coverage,n=this.as.end,r=this.as.chrom,o=this.startAccessor,i=this.endAccessor,s=this.chromAccessor,a=this.weightAccessor;let c,l,u,f=0,d=NaN;const h=this.ends;h.clear();const p=b=>{this._propagate(b),c=null},y=(b,A,S)=>{if(b==A)return;let E=!1;c&&(c[e]===S?(c[n]=A,E=!0):c[e]!=0&&p(c)),E||(c=this.createSegment(b,A,S,u))},v=()=>{let b=0;for(;(b=h.peekValue())!==void 0;)y(d,b,f),d=b,f-=h.pop();d=NaN,c&&p(c)};this.handle=b=>{const A=o(b);let S=0;for(;(S=h.peekValue())!==void 0&&S<A;)y(d,S,f),d=S,f-=h.pop();if(r){let I=s(b);I!==l&&(v(),u=I,l=u)}isNaN(d)||y(d,A,f),d=A;const E=a(b);f+=E,h.push(E,i(b))},this.complete=()=>{v(),super.complete()},this.beginBatch=b=>{v(),l=null,super.beginBatch(b)}}}function HB(t,e,n=i=>+i,r=0,o=t.length){const i=new jl,s=o-r;let a;for(a=0;a<e&&a<s;a++)i.push(a,n(t[r+a]));for(;a<s;a++){const u=n(t[r+a]);u>=i.peekValue()&&(i.push(a,u),i.pop())}const c=[];let l;for(;(l=i.pop())!==void 0;)c.push(t[r+l]);return c.reverse()}class VB{constructor(e,n=-1/0,r=1/0){this.maxSize=e,this.lowerLimit=n,this.upperLimit=r;const o=this.maxSize*2+1;this.lowerLimits=new Float64Array(o),this.upperLimits=new Float64Array(o),this.lowerChildren=new Int32Array(o),this.upperChildren=new Int32Array(o),this.reset()}reset(){this.lowerLimits.fill(0),this.upperLimits.fill(0),this.lowerChildren.fill(0),this.upperChildren.fill(0),this.n=1,this.lowerLimits[0]=this.lowerLimit,this.upperLimits[0]=this.upperLimit}_findSlot(e,n,r=0){if(e>=this.lowerLimits[r]&&n<=this.upperLimits[r]){const o=this.lowerChildren[r];if(o){const i=this._findSlot(e,n,o);return i>=0?i:this._findSlot(e,n,this.upperChildren[r])}else return r}else return-1}reserve(e,n){if(n-e<=0)throw new Error("Cannot reserve an empty or negative-size slot!");if(this.n+1>this.lowerLimits.length)return!1;const r=this._findSlot(e,n);if(r<0)return!1;const o=this.n++,i=this.n++;return this.lowerLimits[o]=this.lowerLimits[r],this.upperLimits[o]=e,this.lowerLimits[i]=n,this.upperLimits[i]=this.upperLimits[r],this.lowerChildren[r]=o,this.upperChildren[r]=i,!0}}class jB extends yt{get behavior(){return qf}constructor(e,n){if(super(e),this.params=e,this._data=[],this.channel=e.channel??"x",!["x","y"].includes(this.channel))throw new Error("Invalid channel: "+this.channel);this.startPosAccessor=Qe(this.params.pos),this.endPosAccessor=Qe(this.params.pos2??this.params.pos),this.startPosBisector=ni(this.startPosAccessor),this.endPosBisector=ni(this.endPosAccessor),this.scoreAccessor=Qe(this.params.score),this.widthAccessor=Qe(this.params.width),this.laneAccessor=this.params.lane?Qe(this.params.lane):o=>0,this.padding=this.params.padding??0,this.reservationMaps=new Map,this.resolution=n.getScaleResolution(this.channel);const r=()=>this._filterAndPropagate();this.schedule=()=>n.context.animator.requestTransition(r),this.resolution.addEventListener("domain",o=>this.schedule()),n._addBroadcastHandler("layoutComputed",()=>this.schedule())}complete(){const e=this.startPosAccessor;this._data.sort((n,r)=>e(n)-e(r));for(const n of new Set(this._data.map(this.laneAccessor)))this.reservationMaps.set(n,new VB(200));this.schedule(),super.complete()}_filterAndPropagate(){super.reset();const e=this.resolution.scale,n=this.resolution.getAxisLength();if(!n)return;for(const s of this.reservationMaps.values())s.reset();const r=e.domain(),i=HB(this._data,70,this.scoreAccessor,this.endPosBisector.left(this._data,r[0]),this.startPosBisector.right(this._data,r[1]));for(const s of i){let a=e(this.startPosAccessor(s))*n,c=e(this.endPosAccessor(s))*n;const l=c-a,u=this.widthAccessor(s)+this.padding*2;let f=(a+c)/2;const d=Math.max(0,(l-u)/2);if(d>0){const h=Math.max(0,u/2-f);f+=Math.min(h,d);const p=Math.max(0,u/2+f-n);f-=Math.min(p,d)}if(this.reservationMaps.get(this.laneAccessor(s)).reserve(f-u/2,f+u/2))if(this.params.asMidpoint){const h=Object.assign({},s);h[this.params.asMidpoint]=e.invert(f/n),this._propagate(h)}else this._propagate(s)}super.complete()}reset(){super.reset(),this._data=[],this.groups=new Map}handle(e){this._data.push(e)}}class qB extends yt{constructor(e,n){super(e,n),this.params=e,this.predicate=void 0}initialize(){let e="";if(WB(this.params))e=this.params.expr;else if(YB(this.params)){const n=this.paramMediator.findValue(this.params.param);if(!n)throw new Error(`Cannot initialize filter transform. Selection parameter "${this.params.param}" not found!`);e=O5(this.params,n)}else throw new Error("Invalid filter params: "+JSON.stringify(this.params));this.predicate=this.paramMediator.createExpression(e),this.predicate.addListener(()=>this.repropagate())}handle(e){this.predicate(e)&&this._propagate(e)}}function WB(t){return"expr"in t}function YB(t){return"param"in t}class QB extends yt{get behavior(){return On}constructor(e){super(e),this.params=e;const n=e.index;if(e.fields){const r=Ft(e.fields).map(i=>Qe(i)),o=Ft(e.as||e.fields);if(r.length!==o.length)throw new Error(`Lengths of "fields" (${r.length}), and "as" (${o.length}) do not match!`);this.handle=i=>{const s=r.map((c,l)=>c(i)??[]),a=s[0].length;for(let c=0;c<a;c++){const l=Object.assign({},i);for(let u=0;u<r.length;u++)l[o[u]]=c<s[u].length?s[u][c]:null;n&&(l[n]=c),this._propagate(l)}}}else this.handle=r=>{for(let o=0;o<r.length;o++){const i=Object.assign({},r[o]);n&&(i[n]=o),this._propagate(i)}}}}const ZB=48;function*XB(t,e=","){const n=e.charCodeAt(0);let r=0;for(let o=0;o<t.length;o++){const i=t.charCodeAt(o);i==n?(yield r,r=0):r=r*10+i-ZB}yield r}class KB extends yt{get behavior(){return On}constructor(e){super(e);const n=Qe(e.exons??"exons"),r=Qe(e.start??"start"),[o,i]=e.as||["exonStart","exonEnd"];this.handle=s=>{let a=r(s),c=a,l=!0;const u=n(s);for(const f of XB(u)){if(l)c=a+f;else{a=c+f;const d=Object.assign({},s);d[o]=c,d[i]=a,this._propagate(d)}l=!l}}}}class JB extends yt{get behavior(){return On}constructor(e){super(e);const n=Ft(e.field).map(i=>Qe(i)),r=Ft(e.separator),o=Ft(e.as||e.field);if(n.length!==r.length||n.length!==o.length)throw new Error(`Lengths of "separator" (${r.length}), "fields" (${n.length}), and "as" (${o.length}) do not match!`);this.handle=i=>{if(n.some(c=>!c(i)))return;const s=n.map((c,l)=>c(i).split(r[l]));$B(s,i);const a=s[0].length;for(let c=0;c<a;c++){const l=Object.assign({},i);for(let u=0;u<n.length;u++)l[o[u]]=s[u][c];this._propagate(l)}}}}function $B(t,e){const n=t.map(r=>r.length);if(!n.every(r=>r==n[0]))throw new Error("Mismatching number of elements in the fields to be split: "+JSON.stringify(e))}class ek extends yt{get behavior(){return Sr}constructor(e,n){super(e,n),this.params=e,this.as=e.as,this.fn=void 0}initialize(){this.fn=this.paramMediator.createExpression(this.params.expr),this.fn.addListener(()=>this.repropagate())}handle(e){e[this.as]=this.fn(e),this._propagate(e)}}class Nb extends yt{get behavior(){return Sr}constructor(e,n){e={channel:"x",...e},super(e),this.params=e;const r=e.channel;if(!["x","y"].includes(r))throw new Error("Invalid channel: "+r);const o=n.getScaleResolution(r).getGenome();if(!o)throw new Error("LinearizeGenomicCoordinate transform requires a locus scale!");const i=Qe(e.chrom),s=Ft(e.pos).map(p=>Qe(p)),a=Ft(e.as);if(s.length!=a.length)throw new Error('The number of "pos" and "as" elements must be equal!');const c=Ft(e.offset);let l;if(c.length==0)l=new Array(s.length).fill(0);else if(c.length==1)l=new Array(s.length).fill(c[0]);else if(c.length==s.length)l=c;else throw new Error(`Invalid "offset" parameter: ${JSON.stringify(e.offset)}!`);const u=new Function("datum","chromOffset","posAccessors",a.map((p,y)=>`datum[${JSON.stringify(p)}] = chromOffset + +posAccessors[${y}](datum) - ${l[y]};`).join(`
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if(e.skipInvalidInput)for(let c=0;c<r.length;c++)i[r[c]]=void 0;else throw new Error(`"${s}" does not match the given regex: ${n.toString()}`)}else if(!e.skipInvalidInput)throw new Error(`Trying to match a non-string field. Encountered type: ${typeof s}, field content: "${s}".`);this._propagate(i)}}}class sk extends yt{get behavior(){return On}constructor(e){super(e),this.params=e;const n=Ft(e.columnRegex).map(d=>new RegExp(d));for(const d of n)if(RegExp("|"+d.source).exec("").length-1!=1)throw new Error(`Regex ${d.toString()} must have exactly one capturing group!`);const r=Ft(e.asValue);if(n.length!=r.length)throw new Error('Lengths of "columnRegex" and "as" are not equal!');const o=e.skipRegex?new RegExp(e.skipRegex):void 0,i=e.asKey||"sample";let s,a,c;const l=d=>{var v;const h=Object.keys(d);for(const b of n)if(!h.some(A=>b.test(A)))throw new Error(`No columns matching the regex ${b.toString()} found in the data!`);const p=new Map;for(const[b,A]of n.entries())for(const S of h){const E=(v=A.exec(S))==null?void 0:v[1];if(E!==void 0){let I=p.get(E);I||(I=[],p.set(E,I)),I[b]=S}}s=[...p.entries()],a=h.filter(b=>!n.some(A=>A.test(b))&&!(o&&o.test(b)));const y=[...a.map(b=>JSON.stringify(b)+": datum["+JSON.stringify(b)+"]"),JSON.stringify(i)+": sampleId",...r.map((b,A)=>JSON.stringify(b)+`: datum[attrs[${A}]]`)];c=new Function("datum","sampleId","attrs",`return {
-`+y.join(`,
+chrM	16299`};function qD(n){if(!(n in _1))throw new Error(`Unknown assembly: ${n}`);return _1[n].split(`
+`).map(e=>{const t=e.split("	");return{name:t[0],size:parseInt(t[1])}})}const YD=/^([A-Za-z]+:)?\/\//;function Or(n,e){if(e&&YD.test(e))return e;const t=typeof n=="function"?n():n;if(!t)return e;if(!e)return t;if(/[#?]/.test(t))throw new Error(`Cannot append to a url with query or hash. Append: ${e}, base: ${t}`);return j1(t)+e}function j1(n){const e=n.replace(/[^/]*$/,"");return e===""?void 0:e.endsWith("://")?n+"/":e}class XD{constructor(e){if(this.config={name:"custom",...e},"baseUrl"in e)throw new Error("The `baseUrl` property in genome config has been removed in GenomeSpy v0.52.0. Use `url` instead. See https://genomespy.app/docs/genomic-data/genomic-coordinates/.");if(!oh(e))throw new Error("Not a genome configuration: "+JSON.stringify(e));if(this.chromosomes=[],this.cumulativeChromPositions=new Map,this.chromosomesByName=new Map,this.startByIndex=[],this.totalSize=0,W1(this.config))this.setChromSizes(this.config.contigs);else if(!ah(this.config)){const t=qD(this.config.name);if(t)this.setChromSizes(t);else throw new Error(`Unknown genome: ${this.config.name}. Please provide contigs or a URL. See https://genomespy.app/docs/genomic-data/genomic-coordinates/.`)}}get name(){return this.config.name}async load(e){if(ah(this.config))try{const t=Or(e,this.config.url),r=await fetch(t);if(!r.ok)throw new Error(`${r.status} ${r.statusText}`);this.setChromSizes(ZD(await r.text()))}catch(t){throw new Error(`Could not load chrom sizes: ${this.config.url}. Reason: ${t.message}`)}}hasChrPrefix(){return this.chromosomes.some(e=>e.name.startsWith("chr"))}setChromSizes(e){let t=0;this.startByIndex=[0];for(let r=0;r<e.length;r++){this.startByIndex.push(t);const i=e[r].size,s={...e[r],continuousStart:t,continuousEnd:t+i,continuousInterval:[t,t+i],index:r,number:r+1,odd:!(r&1)};this.chromosomes.push(s);const o=s.name.replace(/^chr/i,"");for(const a of["chr"+o,"CHR"+o,"Chr"+o,s.number,""+s.number,o,s.name])this.cumulativeChromPositions.set(a,t),this.chromosomesByName.set(a,s);t+=s.size}this.totalSize=t}getExtent(){return[0,this.totalSize]}toContinuous(e,t){let r=this.cumulativeChromPositions.get(e);if(r===void 0)throw new Error("Unknown chromosome/contig: "+e);return r+ +t}toChromosome(e){if(e>this.totalSize)return;e=Math.floor(e);const t=Dn(this.startByIndex,e)-1;if(t>0&&t<=this.chromosomes.length)return this.chromosomes[t-1]}toChromosomal(e){const t=this.toChromosome(e);if(t)return{chrom:t.name,pos:Math.floor(e)-t.continuousStart}}getChromosome(e){return this.chromosomesByName.get(e)}formatInterval(e){return WD(...this.toChromosomalInterval(e))}toChromosomalInterval(e){const t=this.toChromosomal(e[0]+.5),r=this.toChromosomal(e[1]-.5);return r.pos+=1,[t,r]}toContinuousInterval(e){var i;let[t,r]=e;return r||(r=t),[this.toContinuous(t.chrom,t.pos??0),this.toContinuous(r.chrom,r.pos??((i=this.chromosomesByName.get(r.chrom))==null?void 0:i.size))]}toDiscreteChromosomeIntervals(e){const t=e[0],r=e[1],i=[];if(t.chrom===r.chrom)i.push({chrom:t.chrom,startPos:t.pos,endPos:r.pos});else{const s=this.chromosomes.findIndex(a=>a.name===t.chrom),o=this.chromosomes.findIndex(a=>a.name===r.chrom);i.push({chrom:t.chrom,startPos:t.pos,endPos:this.chromosomes[s].size});for(let a=s+1;a<o;a++)i.push({chrom:this.chromosomes[a].name,startPos:0,endPos:this.chromosomes[a].size});i.push({chrom:r.chrom,startPos:0,endPos:r.pos})}return i}continuousToDiscreteChromosomeIntervals(e){return this.toDiscreteChromosomeIntervals([this.toChromosomal(e[0]),this.toChromosomal(e[1])])}parseInterval(e){const t=e.match(/^(chr[0-9A-Z]+)(?::([0-9,]+)(?:-(?:(chr[0-9A-Z]+):)?([0-9,]+))?)?$/);if(t){const r=t[1];if(t.slice(2).every(a=>a===void 0)){const a=this.getChromosome(r);return a?[a.continuousStart,a.continuousEnd]:void 0}const i=t[3]||r,s=parseInt(t[2].replace(/,/g,"")),o=t[4]!==void 0?parseInt(t[4].replace(/,/g,"")):s;return[this.toContinuous(r,s-1),this.toContinuous(i,o)]}}}function ZD(n){return TA(n).map(([e,t])=>({name:e,size:parseInt(t)}))}function Q1(n){return Ge(n)&&"chrom"in n}function KD(n){return n.every(Q1)}function oh(n){return Ge(n)&&("name"in n||ah(n)||W1(n))}function ah(n){return oh(n)&&"url"in n}function W1(n){return oh(n)&&"contigs"in n}class Lo extends Array{constructor(){super(),this.type=void 0}extend(e){return this}extendAll(e){if(e instanceof Lo&&e.type!=this.type)throw new Error(`Cannot combine different types of domains: ${this.type} and ${e.type}`);for(const t of e)this.extend(t);return this}extendAllWithAccessor(e,t){for(const r of e)this.extend(t(r));return this}}class ch extends Lo{constructor(){super(),this.type="quantitative"}extend(e){return e==null||Number.isNaN(e)?this:(e=+e,this.length?e<this[0]?this[0]=e:e>this[1]&&(this[1]=e):(this.push(e),this.push(e)),this)}}class q1 extends Lo{constructor(){super(),this.type="ordinal",this.uniqueValues=new Set}extend(e){return e==null||Number.isNaN(e)?this:(this.uniqueValues.has(e)||(this.uniqueValues.add(e),this.push(e)),this)}}class Y1 extends q1{constructor(){super(),this.type="nominal"}}class JD extends Lo{constructor(e){super();let t=0;for(let r=1;r<e.length;r++)t+=Math.sign(e[r]-e[r-1]);if(Math.abs(t)!=e.length-1)throw new Error("Piecewise domain must be strictly increasing or decreasing: "+JSON.stringify(e));e.forEach(r=>this.push(r))}extend(e){if(this.includes(e))return this;throw new Error("Piecewise domains are immutable and cannot be unioned!")}}const X1={quantitative:ch,index:ch,locus:ch,nominal:Y1,ordinal:q1};function Z1(n,e){if(n=="quantitative"&&$D(e)){const t=new JD(e);return t.type=n,t}else if(X1[n]){const t=new X1[n];return t.type=n,e&&t.extendAll(e),t}throw new Error("Unknown type: "+n)}function $D(n){return n&&n.length>0&&n.length!=2&&n.every(e=>typeof e=="number")}function eI(n){return((n*=2)<=1?n*n*n:(n-=2)*n*n+2)/2}function tI(n,e,t){return n*Math.pow(e/n,t)}le("index",ih,["continuous"]),le("locus",vD,["continuous"]),le("null",Kf,[]);const K1="quantitative",J1="ordinal",$1="nominal",ey="locus",nI="index";class rI{constructor(e){R(this,q);R(this,is,{domain:new Set,range:new Set});R(this,ct);R(this,Yr);R(this,ra,new Set);this.channel=e,this.members=[],this.type=null,this.name=void 0}get zoomExtent(){return(E(this,ct)&&Oe(E(this,ct).type)&&O(this,q,vx).call(this))??[-1/0,1/0]}addEventListener(e,t){E(this,is)[e].add(t)}removeEventListener(e,t){E(this,is)[e].delete(t)}addMember(e){var a;const{channel:t,channelDef:r}=e,i=r.type==null&&this.type;if(t!="sample"&&!r.type&&!uf(t)&&!i)throw new Error(`The "type" property must be defined in channel definition: "${t}": ${JSON.stringify(r)}. Must be one of: "quantitative", "ordinal", "nominal", "locus", "index"`);const s=t=="sample"?"nominal":r.type,o=(a=r==null?void 0:r.scale)==null?void 0:a.name;if(o){if(this.name!==void 0&&o!=this.name)throw new Error(`Shared scales have conflicting names: "${o}" vs. "${this.name}"!`);this.name=o}if(!i){if(!this.type)this.type=s;else if(s!==this.type&&!uf(t))throw new Error(`Can not use shared scale for different data types: ${this.type} vs. ${s}. Use "resolve: independent" for channel ${this.channel}`)}this.members.push(e)}removeMembersByView(e){const t=this.members.length;return this.members=this.members.filter(r=>r.view!==e),this.members.length!==t}getDataDomain(){return this.members.map(e=>{var t;return(t=e.dataDomainSource)==null?void 0:t.call(e,e.channel,this.type)}).filter(e=>!!e).reduce((e,t)=>e.extendAll(t))}reconfigure(){const e=E(this,ct);if(!e||e.type=="null")return;const t=O(this,q,Ax).call(this),r=e.domain(),i=O(this,q,hd).call(this,!0);if(U1({...i,range:void 0},e),e.props=i,O(this,q,dd).call(this),!E(this,Yr)&&Oe(e.type)){const o=e.domain();Ts(o)>0&&G(this,Yr,o)}if(!t){G(this,Yr,e.domain()),O(this,q,Sn).call(this,"domain");return}const s=e.domain();$a(s,r)||(this.isZoomable()?e.domain(r):O(this,q,ti).call(this)?(e.domain(r),this.zoomTo(s,500)):O(this,q,Sn).call(this,"domain"))}get scale(){if(E(this,ct))return E(this,ct);const e=O(this,q,hd).call(this),t=ND({...e,range:void 0});t.props=e,"unknown"in t&&t.unknown(null),G(this,ct,t),O(this,q,dd).call(this),SD(t)&&t.genome(this.getGenome());const r=t.range;if(r){const i=()=>O(this,q,Sn).call(this,"range");t.range=function(s){if(arguments.length)r(s),i();else return r()},i()}return t}getDomain(){return this.scale.domain()}getComplexDomain(){var e;return((e=this.getGenome())==null?void 0:e.toChromosomalInterval(this.getDomain()))??this.getDomain()}isZoomed(){return O(this,q,ti).call(this)&&$a(O(this,q,Fu).call(this),this.getDomain())}isZoomable(){return O(this,q,ti).call(this)&&!!this.scale.props.zoom}zoom(e,t,r){if(!O(this,q,ti).call(this))return!1;const i=this.scale,s=i.domain();let o=[...s],a=i.invert(t);switch(i.props.reverse&&(r=-r),"align"in i&&(a+=i.align()),i.type){case"linear":case"index":case"locus":o=Hx(o,r||0),o=Bd(o,a,e);break;case"log":o=Vx(o,r||0),o=kd(o,a,e);break;case"pow":case"sqrt":{const u=i;o=_x(o,r||0,u.exponent()),o=Nu(o,a,e,u.exponent());break}default:throw new Error("Zooming is not implemented for: "+i.type)}const c=this.zoomExtent;return o=Qx(o,c[0],c[1]),[0,1].some(u=>o[u]!=s[u])?(i.domain(o),O(this,q,Sn).call(this,"domain"),!0):!1}async zoomTo(e,t=!1){if(Is(t)&&(t=t?700:0),!O(this,q,ti).call(this))throw new Error("Not a zoomable scale!");const r=this.fromComplexInterval(e),i=E(this,q,ld).animator,s=this.scale,o=s.domain();if(t>0&&o.length==2){const a=o[1]-o[0],c=r[1]-r[0],u=o[0]+a/2,l=r[0]+c/2,f=o[0]==r[0],d=o[1]==r[1];await i.transition({duration:t,easingFunction:eI,onUpdate:h=>{const p=tI(a,c,h),m=a==c?h:(a-p)/(a-c),g=m*l+(1-m)*u,y=[f?o[0]:g-p/2,d?o[1]:g+p/2];s.domain(y),O(this,q,Sn).call(this,"domain")}}),s.domain(r),O(this,q,Sn).call(this,"domain")}else s.domain(r),i==null||i.requestRender(),O(this,q,Sn).call(this,"domain")}resetZoom(){if(!O(this,q,ti).call(this))throw new Error("Not a zoomable scale!");const e=this.getDomain(),t=O(this,q,Fu).call(this);return[0,1].some(r=>t[r]!=e[r])?(E(this,ct).domain(t),O(this,q,Sn).call(this,"domain"),!0):!1}getZoomLevel(){return this.isZoomable()?Ts(this.zoomExtent)/Ts(this.scale.domain()):1}getAxisLength(){if(this.channel!=="x"&&this.channel!=="y")throw new Error("Axis length is only defined for x and y channels!");const e=this.members.map(t=>{var r;return(r=t.view.coords)==null?void 0:r[this.channel==="x"?"width":"height"]}).filter(t=>t>0);return e.length?e.reduce((t,r)=>Math.min(t,r),1e4):0}getGenome(){var t;if(this.type!=="locus")return;const e=(t=E(this,q,ld).genomeStore)==null?void 0:t.getGenome();if(!e)throw new Error("No genome has been defined!");return e}invertToComplex(e){const t=this.scale;if("invert"in t){const r=t.invert(e);return this.toComplex(r)}else throw new Error("The scale does not support inverting!")}toComplex(e){const t=this.getGenome();return t?t.toChromosomal(e):e}fromComplex(e){return Q1(e)?this.getGenome().toContinuous(e.chrom,e.pos):e}fromComplexInterval(e){return this.type==="locus"&&KD(e)?this.getGenome().toContinuousInterval(e):e}}is=new WeakMap,ct=new WeakMap,Yr=new WeakMap,ra=new WeakMap,q=new WeakSet,ud=function(){return this.members[0].view},ld=function(){return E(this,q,ud).context},Sn=function(e){for(const t of E(this,is)[e].values())t({type:e,scaleResolution:this})},fd=function(){return!!O(this,q,pd).call(this)},Ax=function(){const e=E(this,ct);if(!e)return!1;const t=e.domain();return Oe(e.type)?t.length>2||t.length==2&&(t[0]!==0||t[1]!==0):t.length>0},wx=function(){const e=this.members.map(t=>t.channelDef.scale).filter(t=>t!==void 0);return tu(e,"scale",["domain"])},hd=function(e=!1){const t=O(this,q,wx).call(this);if(t===null||t.type=="null")return{type:"null"};const r={...O(this,q,Sx).call(this,this.type),...t};r.type||(r.type=iI(this.channel,this.type));const i=O(this,q,Fu).call(this,e);return i&&i.length>0?r.domain=i:jn(r.type)&&(r.domain=new Y1),!r.domain&&r.domainMid!==void 0&&(r.domain=[r.domainMin??0,r.domainMax??1]),this.channel=="y"&&jn(r.type)&&r.reverse==null&&(r.reverse=!0),r.range&&r.scheme&&delete r.scheme,!("zoom"in r)&&["index","locus"].includes(r.type)&&(r.zoom=!0),sI(r,this.channel),r},dd=function(){const e=E(this,ct).props,t=e.range;if(E(this,ra).forEach(i=>i.invalidate()),!t||!Ue(t))return;const r=(i,s)=>s?i.slice().reverse():i;if(t.some(Qe)){let i;const s=()=>{E(this,ct).range(r(i.map(o=>o()),e.reverse))};i=t.map(o=>{if(Qe(o)){const a=E(this,q,ud).paramMediator.createExpression(o.expr);return a.addListener(s),E(this,ra).add(a),()=>a(null)}else return()=>o}),s()}else E(this,ct).range(r(t,e.reverse))},Fu=function(e=!1){return O(this,q,pd).call(this)??(this.type==ey?this.getGenome().getExtent():e?this.getDataDomain():[])},pd=function(){const e=this.members.map(t=>t.channelDef).filter(t=>{var r;return(r=t.scale)==null?void 0:r.domain}).map(t=>Z1(t.type,this.fromComplexInterval(t.scale.domain)));if(e.length>0)return e.reduce((t,r)=>t.extendAll(r))},ti=function(){const e=this.scale.type;return Oe(e)},vx=function(){const e=this.scale.props,t=e.zoom;return oI(t)&&Ue(t.extent)?this.fromComplexInterval(t.extent):t&&e.type=="locus"?this.getGenome().getExtent():E(this,Yr)},Sx=function(e){const t=this.channel,r={};return O(this,q,fd).call(this)&&(r.zero=!1),Ao(t)?r.nice=!O(this,q,fd).call(this):Ln(t)?r.scheme=e==$1?"tableau10":e==J1?"blues":"viridis":Pc(t)?r.range=t=="shape"?["circle","square","triangle-up","cross","diamond"]:[]:t=="size"?r.range=[0,400]:t=="angle"&&(r.range=[0,360]),r};function iI(n,e){if(e==nI||e==ey){if(cf(n))return e;throw new Error(`${n} does not support ${e} data type. Only positional channels do.`)}const t={x:["band","band","linear"],y:["band","band","linear"],size:[void 0,"point","linear"],opacity:[void 0,"point","linear"],fillOpacity:[void 0,"point","linear"],strokeOpacity:[void 0,"point","linear"],color:["ordinal","ordinal","linear"],fill:["ordinal","ordinal","linear"],stroke:["ordinal","ordinal","linear"],strokeWidth:[void 0,void 0,"linear"],shape:["ordinal","ordinal",void 0],dx:[void 0,void 0,"null"],dy:[void 0,void 0,"null"],angle:[void 0,void 0,"linear"],sample:["null",void 0,void 0]},i=["sample"].includes(n)?"null":t[n]?t[n][[$1,J1,K1].indexOf(e)]:e==K1?"linear":"ordinal";if(i===void 0)throw new Error(`Channel "${n}" is not compatible with "${e}" data type. Use of a proper scale may be needed.`);return i}function sI(n,e){Ao(e)&&n.type!=="ordinal"&&(n.range=[0,1]),e=="opacity"&&Oe(n.type)&&(n.clamp=!0)}function oI(n){return Ge(n)}function ty(n){const e=new Set;function t(r){for(const i of Object.values(r.resolutions.scale))e.add(i)}for(const r of He(n)){r.visit(t);for(const i of r.getDataAncestors()){if(!i.options.contributesToScaleDomain)break;t(i)}}e.forEach(r=>r.reconfigure())}function uh(...n){for(const e of n)if(e!==void 0)return e}class aI{constructor(e){this.channel=e,this.members=[]}get scaleResolution(){var e;return(e=eo(this.members))==null?void 0:e.view.getScaleResolution(this.channel)}addMember(e){const{view:t}=e,r=t.getScaleResolution(this.channel);if(!r)throw new Error("Cannot find a scale resolution!");if(this.scaleResolution&&r!==this.scaleResolution)throw new Error(`Shared axes must have a shared scale! 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i=r-1>>1,s=this.values[i];if(t>=s)break;this.ids[r]=this.ids[i],this.values[r]=s,r=i}this.ids[r]=e,this.values[r]=t}pop(){if(this.length===0)return;const e=this.ids[0];if(this.length--,this.length>0){const t=this.ids[0]=this.ids[this.length],r=this.values[0]=this.values[this.length],i=this.length>>1;let s=0;for(;s<i;){let o=(s<<1)+1;const a=o+1;let c=this.ids[o],u=this.values[o];const l=this.values[a];if(a<this.length&&l<u&&(o=a,c=this.ids[a],u=l),u>=r)break;this.ids[s]=c,this.values[s]=u,s=o}this.ids[s]=t,this.values[s]=r}return e}peek(){if(this.length!==0)return this.ids[0]}peekValue(){if(this.length!==0)return this.values[0]}shrink(){this.ids.length=this.values.length=this.length}}class SI extends Te{get behavior(){return Ht}constructor(e){super(e),this.params=e,this.startAccessor=ue(e.start),this.endAccessor=ue(e.end),this.chromAccessor=e.chrom?ue(e.chrom):t=>{},this.weightAccessor=e.weight?ue(e.weight):t=>1,this.as={coverage:e.as??"coverage",start:e.asStart??e.start,end:e.asEnd??e.end,chrom:e.asChrom??e.chrom},this.createSegment=new Function("start","end","coverage","chrom","return {"+Object.entries(this.as).filter(([t,r])=>r).map(([t,r])=>`${JSON.stringify(r)}: ${t}`).join(", ")+"};"),this.ends=new ru}reset(){super.reset(),this.initialize()}initialize(){const e=this.as.coverage,t=this.as.end,r=this.as.chrom,i=this.startAccessor,s=this.endAccessor,o=this.chromAccessor,a=this.weightAccessor;let c,u,l,f=0,d=NaN;const h=this.ends;h.clear();const p=y=>{this._propagate(y),c=null},m=(y,x,A)=>{if(y==x)return;let w=!1;c&&(c[e]===A?(c[t]=x,w=!0):c[e]!=0&&p(c)),w||(c=this.createSegment(y,x,A,l))},g=()=>{let y=0;for(;(y=h.peekValue())!==void 0;)m(d,y,f),d=y,f-=h.pop();d=NaN,c&&p(c)};this.handle=y=>{const x=i(y);let A=0;for(;(A=h.peekValue())!==void 0&&A<x;)m(d,A,f),d=A,f-=h.pop();if(r){let S=o(y);S!==u&&(g(),l=S,u=l)}isNaN(d)||m(d,x,f),d=x;const w=a(y);f+=w,h.push(w,s(y))},this.complete=()=>{g(),super.complete()},this.beginBatch=y=>{g(),u=null,super.beginBatch(y)}}}function EI(n,e,t=s=>+s,r=0,i=n.length){const s=new ru,o=i-r;let a;for(a=0;a<e&&a<o;a++)s.push(a,t(n[r+a]));for(;a<o;a++){const l=t(n[r+a]);l>=s.peekValue()&&(s.push(a,l),s.pop())}const c=[];let u;for(;(u=s.pop())!==void 0;)c.push(n[r+u]);return c.reverse()}class CI{constructor(e,t=-1/0,r=1/0){this.maxSize=e,this.lowerLimit=t,this.upperLimit=r;const i=this.maxSize*2+1;this.lowerLimits=new Float64Array(i),this.upperLimits=new Float64Array(i),this.lowerChildren=new Int32Array(i),this.upperChildren=new Int32Array(i),this.reset()}reset(){this.lowerLimits.fill(0),this.upperLimits.fill(0),this.lowerChildren.fill(0),this.upperChildren.fill(0),this.n=1,this.lowerLimits[0]=this.lowerLimit,this.upperLimits[0]=this.upperLimit}_findSlot(e,t,r=0){if(e>=this.lowerLimits[r]&&t<=this.upperLimits[r]){const i=this.lowerChildren[r];if(i){const s=this._findSlot(e,t,i);return s>=0?s:this._findSlot(e,t,this.upperChildren[r])}else return r}else return-1}reserve(e,t){if(t-e<=0)throw new Error("Cannot reserve an empty or negative-size slot!");if(this.n+1>this.lowerLimits.length)return!1;const r=this._findSlot(e,t);if(r<0)return!1;const i=this.n++,s=this.n++;return this.lowerLimits[i]=this.lowerLimits[r],this.upperLimits[i]=e,this.lowerLimits[s]=t,this.upperLimits[s]=this.upperLimits[r],this.lowerChildren[r]=i,this.upperChildren[r]=s,!0}}class DI extends Te{get behavior(){return Wl}constructor(e,t){if(super(e),this.params=e,this._data=[],this.channel=e.channel??"x",!["x","y"].includes(this.channel))throw new Error("Invalid channel: "+this.channel);this.startPosAccessor=ue(this.params.pos),this.endPosAccessor=ue(this.params.pos2??this.params.pos),this.startPosBisector=dr(this.startPosAccessor),this.endPosBisector=dr(this.endPosAccessor),this.scoreAccessor=ue(this.params.score),this.widthAccessor=ue(this.params.width),this.laneAccessor=this.params.lane?ue(this.params.lane):i=>0,this.padding=this.params.padding??0,this.reservationMaps=new Map,this.resolution=t.getScaleResolution(this.channel);const r=()=>this._filterAndPropagate();this.schedule=()=>t.context.animator.requestTransition(r),this.resolution.addEventListener("domain",i=>this.schedule()),t._addBroadcastHandler("layoutComputed",()=>this.schedule())}complete(){const e=this.startPosAccessor;this._data.sort((t,r)=>e(t)-e(r));for(const t of new Set(this._data.map(this.laneAccessor)))this.reservationMaps.set(t,new CI(200));this.schedule(),super.complete()}_filterAndPropagate(){super.reset();const e=this.resolution.scale,t=this.resolution.getAxisLength();if(!t)return;for(const o of this.reservationMaps.values())o.reset();const r=e.domain(),s=EI(this._data,70,this.scoreAccessor,this.endPosBisector.left(this._data,r[0]),this.startPosBisector.right(this._data,r[1]));for(const o of s){let a=e(this.startPosAccessor(o))*t,c=e(this.endPosAccessor(o))*t;const u=c-a,l=this.widthAccessor(o)+this.padding*2;let f=(a+c)/2;const d=Math.max(0,(u-l)/2);if(d>0){const h=Math.max(0,l/2-f);f+=Math.min(h,d);const p=Math.max(0,l/2+f-t);f-=Math.min(p,d)}if(this.reservationMaps.get(this.laneAccessor(o)).reserve(f-l/2,f+l/2))if(this.params.asMidpoint){const h=Object.assign({},o);h[this.params.asMidpoint]=e.invert(f/t),this._propagate(h)}else this._propagate(o)}super.complete()}reset(){super.reset(),this._data=[],this.groups=new Map}handle(e){this._data.push(e)}}class II extends Te{constructor(e,t){super(e,t),this.params=e,this.predicate=void 0}initialize(){let e="";if(TI(this.params))e=this.params.expr;else if(BI(this.params)){const t=this.paramMediator.findValue(this.params.param);if(!t)throw new Error(`Cannot initialize filter transform. Selection parameter "${this.params.param}" not found!`);e=g8(this.params,t)}else throw new Error("Invalid filter params: "+JSON.stringify(this.params));this.predicate=this.paramMediator.createExpression(e),this.predicate.addListener(()=>this.repropagate())}handle(e){this.predicate(e)&&this._propagate(e)}}function TI(n){return"expr"in n}function BI(n){return"param"in n}class kI extends Te{get behavior(){return Ht}constructor(e){super(e),this.params=e;const t=e.index;if(e.fields){const r=He(e.fields).map(s=>ue(s)),i=He(e.as||e.fields);if(r.length!==i.length)throw new Error(`Lengths of "fields" (${r.length}), and "as" (${i.length}) do not match!`);this.handle=s=>{const o=r.map((c,u)=>c(s)??[]),a=o[0].length;for(let c=0;c<a;c++){const u=Object.assign({},s);for(let l=0;l<r.length;l++)u[i[l]]=c<o[l].length?o[l][c]:null;t&&(u[t]=c),this._propagate(u)}}}else this.handle=r=>{for(let i=0;i<r.length;i++){const s=Object.assign({},r[i]);t&&(s[t]=i),this._propagate(s)}}}}const FI=48;function*PI(n,e=","){const t=e.charCodeAt(0);let r=0;for(let i=0;i<n.length;i++){const s=n.charCodeAt(i);s==t?(yield r,r=0):r=r*10+s-FI}yield r}class MI extends Te{get behavior(){return Ht}constructor(e){super(e);const t=ue(e.exons??"exons"),r=ue(e.start??"start"),[i,s]=e.as||["exonStart","exonEnd"];this.handle=o=>{let a=r(o),c=a,u=!0;const l=t(o);for(const f of PI(l)){if(u)c=a+f;else{a=c+f;const d=Object.assign({},o);d[i]=c,d[s]=a,this._propagate(d)}u=!u}}}}class RI extends Te{get behavior(){return Ht}constructor(e){super(e);const t=He(e.field).map(s=>ue(s)),r=He(e.separator),i=He(e.as||e.field);if(t.length!==r.length||t.length!==i.length)throw new Error(`Lengths of "separator" (${r.length}), "fields" (${t.length}), and "as" (${i.length}) do not match!`);this.handle=s=>{if(t.some(c=>!c(s)))return;const o=t.map((c,u)=>c(s).split(r[u]));OI(o,s);const a=o[0].length;for(let c=0;c<a;c++){const u=Object.assign({},s);for(let l=0;l<t.length;l++)u[i[l]]=o[l][c];this._propagate(u)}}}}function OI(n,e){const t=n.map(r=>r.length);if(!t.every(r=>r==t[0]))throw new Error("Mismatching number of elements in the fields to be split: "+JSON.stringify(e))}class NI extends Te{get behavior(){return Rn}constructor(e,t){super(e,t),this.params=e,this.as=e.as,this.fn=void 0}initialize(){this.fn=this.paramMediator.createExpression(this.params.expr),this.fn.addListener(()=>this.repropagate())}handle(e){e[this.as]=this.fn(e),this._propagate(e)}}class hy extends Te{get behavior(){return Rn}constructor(e,t){e={channel:"x",...e},super(e),this.params=e;const r=e.channel;if(!["x","y"].includes(r))throw new Error("Invalid channel: "+r);const i=t.getScaleResolution(r).getGenome();if(!i)throw new Error("LinearizeGenomicCoordinate transform requires a locus scale!");const s=ue(e.chrom),o=He(e.pos).map(p=>ue(p)),a=He(e.as);if(o.length!=a.length)throw new Error('The number of "pos" and "as" elements must be equal!');const c=He(e.offset);let u;if(c.length==0)u=new Array(o.length).fill(0);else if(c.length==1)u=new Array(o.length).fill(c[0]);else if(c.length==o.length)u=c;else throw new Error(`Invalid "offset" parameter: ${JSON.stringify(e.offset)}!`);const l=new Function("datum","chromOffset","posAccessors",a.map((p,m)=>`datum[${JSON.stringify(p)}] = chromOffset + +posAccessors[${m}](datum) - ${u[m]};`).join(`
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v/(u-(b+0))*(v/y)}}break;default:c=(u,f)=>u,l=(u,f)=>1}for(const u of s){r&&u.sort(r);const f=l(u,o);let d=0;for(const h of u){const p=d+o(h);a(h)&&(h[n[0]]=c(d,f),h[n[1]]=c(p,f),this._propagate(h),d=p)}}super.complete()}}class ck extends yt{get behavior(){return On}constructor(e){super(e),this.params=e;const n=Qe(e.field??"sequence"),[r,o]=e.as??["pos","sequence"];this.handle=i=>{const s=Object.assign({},i,{[o]:"",[r]:0}),a=n(i);for(let c=0;c<a.length;c++){const l=Object.assign({},s);l[r]=c,l[o]=a.charAt(c),this._propagate(l)}}}}const Ub={count:t=>t.length,valid:a3,sum:Ts,min:Zu,max:Qu,mean:w3,median:x3,variance:c3};class lk extends yt{get behavior(){return On}constructor(e){if(super(e),this.params=e,this.buffer=[],this.ops=[],this.as=[],e.fields){if(e.fields.length!=e.ops.length)throw new Error("Fields and ops must have the same length!");if(e.as&&e.as.length!=e.ops.length)throw new Error('If "as" is defined, "fields" and "as" must have the same length!');e.fields.forEach((n,r)=>{const o=Qe(n),i=Ub[e.ops[r]];this.ops.push(s=>i(s,o)),this.as.push(e.as?e.as[r]:`${e.ops[r]}_${e.fields[r]}`)})}else this.ops.push(n=>Ub.count(n)),this.as.push("count")}reset(){super.reset(),this.buffer=[]}handle(e){this.buffer.push(e)}complete(){const e=this.params,n=e==null?void 0:e.groupby;if((n==null?void 0:n.length)>0){const r=n.map(i=>Qe(i)),o=Cc(this.buffer,...r);for(const[i,s]of ud(o)){const a={};for(let c=0;c<n.length;c++)a[n[c]]=i[c];this.ops.forEach((c,l)=>{a[this.as[l]]=c(s)}),this._propagate(a)}}else{const r={};this.ops.forEach((o,i)=>{r[this.as[i]]=o(this.buffer)}),this._propagate(r)}super.complete()}}const uk={aggregate:lk,collect:Ob,coverage:GB,filterScoredLabels:jB,filter:qB,flatten:QB,flattenCompressedExons:KB,flattenDelimited:JB,flattenSequence:ck,formula:ek,identifier:Yf,linearizeGenomicCoordinate:Nb,measureText:tk,pileup:rk,project:ik,regexExtract:ok,regexFold:sk,sample:ab,stack:ak};function fk(t,e){const n=uk[t.type];if(n)return new n(t,e);throw new Error("Unknown transform: "+t.type)}function Gb(t,e=[]){if(!jb(t)&&!Vb(t))return;const n={...t.format};if(n.type??(n.type=Vb(t)&&dk(e)),n.parse??(n.parse="auto"),!n.type)throw new Error("Format for the data source was not defined and it could not be inferred: "+JSON.stringify(t));return n}function hk(t){var e;return((e=ff(t))==null?void 0:e.responseType)??"text"}function dk(t){var e;if(Array.isArray(t)&&(t=t[0]),t)return(e=t.match(/\.(csv|tsv|json)/))==null?void 0:e[1]}const Hb=t=>typeof t!="object"?pk:gk,pk=t=>({data:t}),gk=t=>t;function Vb(t){return"url"in t}class Ao extends Wf{constructor(n){super();Gt(this,"view");this.view=n}get identifier(){}setLoadingStatus(n,r){this.view.context.setDataLoadingStatus(this.view,n,r)}get paramMediator(){return this.view.paramMediator}handle(n){throw new Error("Source does not handle incoming data!")}async load(){}repropagate(){this.load()}}function jb(t){return"values"in t}class mk extends Ao{constructor(n,r){var o;super(r);he(this,Ka);if(this.params=n,typeof n.values=="string"&&!((o=n==null?void 0:n.format)!=null&&o.type))throw new Error("Data format type (csv, dsv, ...) must be specified if a string is provided!")}get label(){return"inlineSource"}isTrivial(){const n=this.params.values,r=Array.isArray(n)?n[0]:n;return!!(r&&Object.keys(r).length==0&&r.constructor===Object)}updateDynamicData(n){pe(this,Ka,Z0).call(this,n)}loadSynchronously(){pe(this,Ka,Z0).call(this,this.params.values)}async load(){this.loadSynchronously()}}Ka=new WeakSet,Z0=function(n){let r=[],o=i=>i;if(Array.isArray(n))n.length>0&&(r=n,o=Hb(n[0]));else if(typeof n=="object")r=[n];else if(typeof n=="string")r=hf(n,Gb(this.params));else throw new Error('"values" in data configuration is not an array, object, or a string!');this.reset(),this.beginBatch({type:"file"});for(const i of r)this._propagate(o(i));this.complete()};function yk(t){return"url"in t}class bk extends Ao{constructor(n,r){super(r);he(this,Cu);this.params=ml(r.paramMediator,n,()=>this.load()),this.baseUrl=r==null?void 0:r.getBaseUrl()}get identifier(){return JSON.stringify({params:this.params,baseUrl:this.baseUrl})}get label(){return"urlSource"}async load(){const n=cn(this.params.url),r=typeof n=="object"&&"urlsFromFile"in n?await pe(this,Cu,Yv).call(this,n):(Array.isArray(n)?n:[n]).map(c=>Si(this.baseUrl,c)),o=Gb(this.params,r),i=hk(o.type);if(r.length===0||!r[0]){this.reset(),this.complete();return}const s=async c=>{try{const l=await fetch(c);if(!l.ok)throw new Error(`${l.status} ${l.statusText}`);return typeof l[i]=="function"?l[i]():l.text()}catch(l){throw new Error(`Could not load data: ${c}. Reason: ${l.message}`)}},a=(c,l)=>{try{const u=hf(c,o);this.beginBatch({type:"file",url:l});for(const f of u)this._propagate(f)}catch(u){throw new Error(`Cannot parse: ${l}: ${u.message}`)}};this.setLoadingStatus("loading"),this.reset();try{await Promise.all(r.map(c=>s(c).then(a))),this.setLoadingStatus("complete")}catch(c){this.setLoadingStatus("error",c.message)}this.complete()}}Cu=new WeakSet,Yv=async function(n){const r=Si(this.baseUrl,n.urlsFromFile),o=await fetch(r);if(!o.ok)throw new Error(`Cannot load "${r}": ${o.status} ${o.statusText}`);const i=await o.text();return hf(i,{type:n.type??"tsv"}).map(a=>typeof a=="string"?a:a.url).map(a=>Si(r,a))};function wk(t){return"sequence"in t}class xk extends Ao{constructor(e,n){if(super(n),this.sequence=ml(n.paramMediator,e.sequence,()=>this.loadSynchronously()),!("start"in this.sequence))throw new Error("'start' is missing from sequence parameters!");if(!("stop"in this.sequence))throw new Error("'stop' is missing from sequence parameters!")}get label(){return"sequenceSource"}loadSynchronously(){const e=cn(this.sequence.as)??"data",n=cn(this.sequence.start)??0,r=cn(this.sequence.step)??1,o=cn(this.sequence.stop);this.reset(),this.beginBatch({type:"file"});for(let i=n;i<o;i+=r)this._propagate({[e]:i});this.complete()}async load(){this.loadSynchronously()}}class fd extends Ao{constructor(n,r){super(n);Gt(this,"initializedPromise",Promise.resolve());if(r){if(r!=="x"&&r!=="y")throw new Error(`Invalid channel specified for the lazy data source: ${r}. Must be either "x" or "y"`)}else throw new Error('No channel has been specified for the lazy data source. Must be either "x" or "y".');if(this.channel=r,this.scaleResolution=this.view.getScaleResolution(r),!this.scaleResolution){const i=[`The lazy data source cannot find a resolved scale for channel "${r}".`];throw this.view instanceof en||i.push('Make sure the view has a "shared" scale resolution as it is not a unit view.'),new Error(i.join(" "))}const o=()=>{this.view.isVisible()&&this.onDomainChanged(this.scaleResolution.getDomain(),this.scaleResolution.getComplexDomain())};this.scaleResolution.addEventListener("domain",o),this.view.context.addBroadcastListener("layoutComputed",o)}get genome(){return this.scaleResolution.getGenome()}onDomainChanged(n,r){}requestRender(){this.view.context.animator.requestRender()}async load(){this.reset(),this.complete()}publishData(n){this.reset(),this.beginBatch({type:"file"});for(const r of n)for(const o of r)this._propagate(o);this.complete(),sd(this.view)}}class vk extends fd{constructor(n,r){const o={...n};super(r,o.channel);Gt(this,"ticks",[]);this.params=n}get label(){return"axisTickSource"}async load(){this.ticks=null,this.onDomainChanged()}onDomainChanged(){const n=this.scaleResolution.scale,r=this.scaleResolution.getAxisLength(),o=this.params.axis,i=l=>25+60*r1(100,700,l),s=Ht(o.tickCount)?o.tickCount:Math.round(r/i(r)),a=lb(n,s,o.tickMinStep),c=o.values?ub(n,o.values,a):WD(n,a);if(this.ticks==null||!Uc(c,this.ticks)){this.ticks=c;const l=QD(n,s,o.format);this.publishData([c.map(u=>({value:u,label:l(u)}))])}}}class Ak extends fd{constructor(e,n){super(n,e.channel)}get label(){return"axisGenomeSource"}async load(){this.publishData([this.genome.chromosomes])}}function ql(t,e,n=!0){let r,o=s=>{};return function(...a){return new Promise((c,l)=>{const u=()=>{clearTimeout(r),o=f=>{},c(t(...a))};n&&o("debounced"),clearTimeout(r),o=l,r=window.setTimeout(u,typeof e=="function"?e():e)})}}class Ta extends fd{constructor(){super(...arguments);he(this,$o,new AbortController);he(this,es,[0,0]);he(this,ts,[0,0]);he(this,Ja,0);Gt(this,"params")}setupDebouncing(n){const r=()=>cn(n.debounce),o=n.debounceMode;if(o=="domain")this.onDomainChanged=ql(this.onDomainChanged.bind(this),r,!1);else if(o=="window")this.loadInterval=ql(this.loadInterval.bind(this),r,!1);else throw new Error("Invalid debounceMode: "+o)}onDomainChanged(n){var o;Ae(this,ts,n);const r=cn((o=this.params)==null?void 0:o.windowSize)??-1;n[1]-n[0]>r||this.callIfWindowsChanged(n,r,async i=>{await this.initializedPromise,this.loadInterval(i)})}reloadLastDomain(){const n=j(this,ts);Ae(this,ts,[0,0]),Ae(this,es,[0,0]),this.onDomainChanged(n)}async loadInterval(n){}async discretizeAndLoad(n,r){j(this,$o).abort(),this.setLoadingStatus("loading"),Ae(this,$o,new AbortController);const o=j(this,$o).signal,i=this.genome.continuousToDiscreteChromosomeIntervals(n);try{const s=await Promise.all(i.map(async a=>r(a,o)));if(!o.aborted)return this.setLoadingStatus("complete"),s}catch(s){if(!o.aborted)throw this.setLoadingStatus("error",s.message),s}}callIfWindowsChanged(n,r,o){const i=[Math.max(Math.floor(n[0]/r)*r,0),Math.min(Math.ceil(n[1]/r)*r,this.genome.totalSize)],s=j(this,es);(r!==j(this,Ja)||i[0]<s[0]||i[1]>s[1])&&(Ae(this,es,i),Ae(this,Ja,r),o(i))}}$o=new WeakMap,es=new WeakMap,ts=new WeakMap,Ja=new WeakMap;class Ek extends Ta{constructor(e,n){const r={channel:"x",windowSize:7e3,debounce:200,debounceMode:"window",...e};if(super(n,r.channel),this.params=r,!this.params.url)throw new Error("No URL provided for IndexedFastaSource");this.setupDebouncing(this.params),this.initializedPromise=new Promise(o=>{Promise.all([Promise.resolve().then(()=>hR),Promise.resolve().then(()=>RR),Promise.resolve().then(()=>_a)]).then(([{Buffer:i},{IndexedFasta:s},{RemoteFile:a}])=>{typeof window<"u"&&(window.Buffer??(window.Buffer=i));const c=l=>new a(Ca(l,this.view.getBaseUrl()));this.fasta=new s({fasta:c(this.params.url),fai:c(this.params.indexUrl??this.params.url+".fai")}),o()})})}get label(){return"bigWigSource"}async loadInterval(e){const n=await this.discretizeAndLoad(e,async(r,o)=>this.fasta.getSequence(r.chrom,r.startPos,r.endPos,{signal:o}).then(i=>({chrom:r.chrom,start:r.startPos,sequence:i})));n&&this.publishData([n])}}class Sk extends Ta{constructor(n,r){const o={pixelsPerBin:2,channel:"x",debounce:200,debounceMode:"window",...n},i=ml(r.paramMediator,o,s=>{s.includes("url")?pe(this,$a,X0).call(this).then(()=>this.reloadLastDomain()):s.includes("pixelsPerBin")&&this.reloadLastDomain()});super(r,i.channel);he(this,$a);he(this,ns,[]);he(this,rs);if(this.params=i,!this.params.url)throw new Error("No URL provided for BigWigSource");this.setupDebouncing(this.params),pe(this,$a,X0).call(this)}get label(){return"bigWigSource"}async onDomainChanged(n){await this.initializedPromise;const r=this.scaleResolution.getAxisLength()||700,o=Ck(n,r,j(this,ns)),i=Math.max(o*r,5e3);this.callIfWindowsChanged(n,i,s=>this.loadInterval(s,o))}async loadInterval(n,r){const o=.5/r/cn(this.params.pixelsPerBin),i=await this.discretizeAndLoad(n,(s,a)=>j(this,rs).getFeatures(s.chrom,s.startPos,s.endPos,{scale:o,signal:a}).then(c=>c.map(l=>({chrom:s.chrom,start:l.start,end:l.end,score:l.score}))));i&&this.publishData(i)}}ns=new WeakMap,rs=new WeakMap,$a=new WeakSet,X0=function(){return this.initializedPromise=new Promise((n,r)=>{Promise.all([Promise.resolve().then(()=>Ax),Promise.resolve().then(()=>_a)]).then(([{BigWig:o},{RemoteFile:i}])=>{Ae(this,rs,new o({filehandle:new i(Ca(cn(this.params.url),this.view.getBaseUrl()))})),this.setLoadingStatus("loading"),j(this,rs).getHeader().then(s=>{Ae(this,ns,s.zoomLevels.map(a=>a.reductionLevel).reverse()),j(this,ns).push(1),this.setLoadingStatus("complete"),n()}).catch(s=>{this.load(),this.setLoadingStatus("error",`${cn(this.params.url)}: ${s.message}`),r(s)})})}),this.initializedPromise};function Ck(t,e,n){const r=(t[1]-t[0])/e;return n.find(o=>o<r)??n.at(-1)}class Ik extends Ta{constructor(n,r){const o={channel:"x",windowSize:1e6,debounce:200,debounceMode:"window",...n},i=ml(r.paramMediator,o,s=>{s.includes("url")?pe(this,ec,K0).call(this).then(()=>this.reloadLastDomain()):s.includes("windowSize")&&this.reloadLastDomain()});super(r,i.channel);he(this,ec);Gt(this,"parser");Gt(this,"bbi");Gt(this,"parseLine");if(this.params=i,!this.params.url)throw new Error("No URL provided for BigBedSource");this.setupDebouncing(this.params),pe(this,ec,K0).call(this)}get label(){return"bigBedSource"}async loadInterval(n){const r=await this.discretizeAndLoad(n,async(o,i)=>this.bbi.getFeatures(o.chrom,o.startPos,o.endPos,{signal:i}).then(s=>s.map(a=>this.parseLine(o.chrom,a))));r&&this.publishData(r)}}ec=new WeakSet,K0=function(){return this.initializedPromise=new Promise((n,r)=>{Promise.all([Promise.resolve().then(()=>W9),Promise.resolve().then(()=>Ax),Promise.resolve().then(()=>_a)]).then(([o,{BigBed:i},{RemoteFile:s}])=>{const a=o.default;this.bbi=new i({filehandle:new s(Ca(cn(this.params.url),this.view.getBaseUrl()))}),this.setLoadingStatus("loading"),this.bbi.getHeader().then(async c=>{this.parser=new a({autoSql:c.autoSql});try{const l=Tk(this.parser);this.parseLine=(u,f)=>l(u,f.start,f.end,f.rest)}catch{this.parseLine=(u,f)=>this.parser.parseLine(`${u}	${f.start}	${f.end}	${f.rest}`)}this.setLoadingStatus("complete"),n()}).catch(c=>{this.load(),this.setLoadingStatus("error",`${cn(this.params.url)}: ${c.message}`),r(c)})})}),this.initializedPromise};function Tk(t){const e=t.autoSql.fields.filter(A=>A.type).slice(3);let n=0,r="",o=0,i={};const s="	",a=s.charCodeAt(0),c=48,l=45;function u(){let A=r.indexOf(s,n);A<0&&(A=o);const S=r.substring(n,A);return n=A+1,S}function f(){let A=0,S=r.charCodeAt(n),E=1;S===l&&(E=-1,n++,S=r.charCodeAt(n));do{if(S===a){n++;break}A=A*10+S-c,S=r.charCodeAt(++n)}while(n<o);return A*E}const d=e.map(A=>`${JSON.stringify(A.name)}: ${A.isNumeric?"0":"emptyString"}`),h=new Function(`
+};`)},l=d=>{o||u(d);for(let h=0;h<o.length;h++){const[p,m]=o[h],g=c(d,p,m);this._propagate(g)}},f=d=>{u(d),l(d),this.handle=l};this.handle=f,this.beginBatch=d=>{cm(d)&&(this.handle=f),super.beginBatch(d)}}}class _I extends Te{get behavior(){return Rn}constructor(e){super(e),this.params=e,this.buffer=[]}reset(){this.buffer=[]}handle(e){this.buffer.push(e)}complete(){const e=this.params,t=e.as||["y0","y1"],r=e.sort?Pd(e.sort.field,e.sort.order):void 0,i=e.field?ue(e.field):()=>1,s=e.groupby.map(l=>ue(l)),o=WA(this.buffer,l=>s.map(f=>f(l)).join()).map(l=>l[1]);let a=l=>!0;if(e.baseField){const l=ue(e.baseField);a=f=>l(f)!==null}let c,u;switch(e.offset){case"normalize":c=(l,f)=>l/f,u=(l,f)=>Gs(l,f);break;case"center":c=(l,f)=>l-f/2,u=(l,f)=>Gs(l,f);break;case"information":{const l=Math.log2(e.cardinality??4);c=(f,d)=>f/d,u=(f,d)=>{const p=Gs(f,x=>+!a(x)),m=Gs(f,d),g=m-p;let y=0;for(let x=0;x<f.length;x++){const A=f[x];if(a(A)){const w=d(A)/g;y-=w*Math.log2(w)}}return g/(l-(y+0))*(g/m)}}break;default:c=(l,f)=>l,u=(l,f)=>1}for(const l of o){r&&l.sort(r);const f=u(l,i);let d=0;for(const h of l){const p=d+i(h);a(h)&&(h[t[0]]=c(d,f),h[t[1]]=c(p,f),this._propagate(h),d=p)}}super.complete()}}class jI extends Te{get behavior(){return Ht}constructor(e){super(e),this.params=e;const t=ue(e.field??"sequence"),[r,i]=e.as??["pos","sequence"];this.handle=s=>{const o=Object.assign({},s,{[i]:"",[r]:0}),a=t(s);for(let c=0;c<a.length;c++){const u=Object.assign({},o);u[r]=c,u[i]=a.charAt(c),this._propagate(u)}}}}const py={count:n=>n.length,valid:GA,sum:Gs,min:Ku,max:Zu,mean:JA,median:$A,variance:HA};class QI extends Te{get behavior(){return Ht}constructor(e){if(super(e),this.params=e,this.buffer=[],this.ops=[],this.as=[],e.fields){if(e.fields.length!=e.ops.length)throw new Error("Fields and ops must have the same length!");if(e.as&&e.as.length!=e.ops.length)throw new Error('If "as" is defined, "fields" and "as" must have the same length!');e.fields.forEach((t,r)=>{const i=ue(t),s=py[e.ops[r]];this.ops.push(o=>s(o,i)),this.as.push(e.as?e.as[r]:`${e.ops[r]}_${e.fields[r]}`)})}else this.ops.push(t=>py.count(t)),this.as.push("count")}reset(){super.reset(),this.buffer=[]}handle(e){this.buffer.push(e)}complete(){const e=this.params,t=e==null?void 0:e.groupby;if((t==null?void 0:t.length)>0){const r=t.map(s=>ue(s)),i=za(this.buffer,...r);for(const[s,o]of hh(i)){const a={};for(let c=0;c<t.length;c++)a[t[c]]=s[c];this.ops.forEach((c,u)=>{a[this.as[u]]=c(o)}),this._propagate(a)}}else{const r={};this.ops.forEach((i,s)=>{r[this.as[s]]=i(this.buffer)}),this._propagate(r)}super.complete()}}const WI={aggregate:QI,collect:fy,coverage:SI,filterScoredLabels:DI,filter:II,flatten:kI,flattenCompressedExons:MI,flattenDelimited:RI,flattenSequence:jI,formula:NI,identifier:Yl,linearizeGenomicCoordinate:hy,measureText:LI,pileup:UI,project:GI,regexExtract:HI,regexFold:VI,sample:M1,stack:_I};function qI(n,e){const t=WI[n.type];if(t)return new t(n,e);throw new Error("Unknown transform: "+n.type)}function my(n,e=[]){if(!by(n)&&!yy(n))return;const t={...n.format};if(t.type??(t.type=yy(n)&&XI(e)),t.parse??(t.parse="auto"),!t.type)throw new Error("Format for the data source was not defined and it could not be inferred: "+JSON.stringify(n));return t}function YI(n){var e;return((e=hl(n))==null?void 0:e.responseType)??"text"}function XI(n){var e;if(Array.isArray(n)&&(n=n[0]),n)return(e=n.match(/\.(csv|tsv|json)/))==null?void 0:e[1]}const gy=n=>typeof n!="object"?ZI:KI,ZI=n=>({data:n}),KI=n=>n;function yy(n){return"url"in n}class Nr extends ql{constructor(t){super();Y(this,"view");this.view=t}get identifier(){}setLoadingStatus(t,r){this.view.context.setDataLoadingStatus(this.view,t,r)}get paramMediator(){return this.view.paramMediator}handle(t){throw new Error("Source does not handle incoming data!")}async load(){}repropagate(){this.load()}}function by(n){return"values"in n}class JI extends Nr{constructor(t,r){var i;super(r);R(this,ua);if(this.params=t,typeof t.values=="string"&&!((i=t==null?void 0:t.format)!=null&&i.type))throw new Error("Data format type (csv, dsv, ...) must be specified if a string is provided!")}get label(){return"inlineSource"}isTrivial(){const t=this.params.values,r=Array.isArray(t)?t[0]:t;return!!(r&&Object.keys(r).length==0&&r.constructor===Object)}updateDynamicData(t){O(this,ua,Ad).call(this,t)}loadSynchronously(){O(this,ua,Ad).call(this,this.params.values)}async load(){this.loadSynchronously()}}ua=new WeakSet,Ad=function(t){let r=[],i=s=>s;if(Array.isArray(t))t.length>0&&(r=t,i=gy(t[0]));else if(typeof t=="object")r=[t];else if(typeof t=="string")r=dl(t,my(this.params));else throw new Error('"values" in data configuration is not an array, object, or a string!');this.reset(),this.beginBatch({type:"file"});for(const s of r)this._propagate(i(s));this.complete()};function $I(n){return"url"in n}class e9 extends Nr{constructor(t,r){super(r);R(this,Cu);this.params=Bc(r.paramMediator,t,()=>this.load()),this.baseUrl=r==null?void 0:r.getBaseUrl()}get identifier(){return JSON.stringify({params:this.params,baseUrl:this.baseUrl})}get label(){return"urlSource"}async load(){const t=gt(this.params.url),r=typeof t=="object"&&"urlsFromFile"in t?await O(this,Cu,Ix).call(this,t):(Array.isArray(t)?t:[t]).map(c=>Or(this.baseUrl,c)),i=my(this.params,r),s=YI(i.type);if(r.length===0||!r[0]){this.reset(),this.complete();return}const o=async c=>{try{const u=await fetch(c);if(!u.ok)throw new Error(`${u.status} ${u.statusText}`);return typeof u[s]=="function"?u[s]():u.text()}catch(u){throw new Error(`Could not load data: ${c}. Reason: ${u.message}`)}},a=(c,u)=>{try{const l=dl(c,i);this.beginBatch({type:"file",url:u});for(const f of l)this._propagate(f)}catch(l){throw new Error(`Cannot parse: ${u}: ${l.message}`)}};this.setLoadingStatus("loading"),this.reset();try{await Promise.all(r.map(c=>o(c).then(a))),this.setLoadingStatus("complete")}catch(c){this.setLoadingStatus("error",c.message)}this.complete()}}Cu=new WeakSet,Ix=async function(t){const r=Or(this.baseUrl,t.urlsFromFile),i=await fetch(r);if(!i.ok)throw new Error(`Cannot load "${r}": ${i.status} ${i.statusText}`);const s=await i.text();return dl(s,{type:t.type??"tsv"}).map(a=>typeof a=="string"?a:a.url).map(a=>Or(r,a))};function t9(n){return"sequence"in n}class n9 extends Nr{constructor(e,t){if(super(t),this.sequence=Bc(t.paramMediator,e.sequence,()=>this.loadSynchronously()),!("start"in this.sequence))throw new Error("'start' is missing from sequence parameters!");if(!("stop"in this.sequence))throw new Error("'stop' is missing from sequence parameters!")}get label(){return"sequenceSource"}loadSynchronously(){const e=gt(this.sequence.as)??"data",t=gt(this.sequence.start)??0,r=gt(this.sequence.step)??1,i=gt(this.sequence.stop);this.reset(),this.beginBatch({type:"file"});for(let s=t;s<i;s+=r)this._propagate({[e]:s});this.complete()}async load(){this.loadSynchronously()}}class dh extends Nr{constructor(t,r){super(t);Y(this,"initializedPromise",Promise.resolve());if(r){if(r!=="x"&&r!=="y")throw new Error(`Invalid channel specified for the lazy data source: ${r}. Must be either "x" or "y"`)}else throw new Error('No channel has been specified for the lazy data source. Must be either "x" or "y".');if(this.channel=r,this.scaleResolution=this.view.getScaleResolution(r),!this.scaleResolution){const s=[`The lazy data source cannot find a resolved scale for channel "${r}".`];throw this.view instanceof ft||s.push('Make sure the view has a "shared" scale resolution as it is not a unit view.'),new Error(s.join(" "))}const i=()=>{this.view.isVisible()&&this.onDomainChanged(this.scaleResolution.getDomain(),this.scaleResolution.getComplexDomain())};this.scaleResolution.addEventListener("domain",i),this.view.context.addBroadcastListener("layoutComputed",i)}get genome(){return this.scaleResolution.getGenome()}onDomainChanged(t,r){}requestRender(){this.view.context.animator.requestRender()}async load(){this.reset(),this.complete()}publishData(t){this.reset(),this.beginBatch({type:"file"});for(const r of t)for(const i of r)this._propagate(i);this.complete(),ty(this.view)}}class r9 extends dh{constructor(t,r){const i={...t};super(r,i.channel);Y(this,"ticks",[]);this.params=t}get label(){return"axisTickSource"}async load(){this.ticks=null,this.onDomainChanged()}onDomainChanged(){const t=this.scaleResolution.scale,r=this.scaleResolution.getAxisLength(),i=this.params.axis,s=u=>25+60*Bm(100,700,u),o=Ze(i.tickCount)?i.tickCount:Math.round(r/s(r)),a=O1(t,o,i.tickMinStep),c=i.values?N1(t,i.values,a):ED(t,a);if(this.ticks==null||!$a(c,this.ticks)){this.ticks=c;const u=DD(t,o,i.format);this.publishData([c.map(l=>({value:l,label:u(l)}))])}}}class i9 extends dh{constructor(e,t){super(t,e.channel)}get label(){return"axisGenomeSource"}async load(){this.publishData([this.genome.chromosomes])}}function iu(n,e,t=!0){let r,i=o=>{};return function(...a){return new Promise((c,u)=>{const l=()=>{clearTimeout(r),i=f=>{},c(n(...a))};t&&i("debounced"),clearTimeout(r),i=u,r=window.setTimeout(l,typeof e=="function"?e():e)})}}class Ho extends dh{constructor(){super(...arguments);R(this,fs,new AbortController);R(this,hs,[0,0]);R(this,ds,[0,0]);R(this,la,0);Y(this,"params")}setupDebouncing(t){const r=()=>gt(t.debounce),i=t.debounceMode;if(i=="domain")this.onDomainChanged=iu(this.onDomainChanged.bind(this),r,!1);else if(i=="window")this.loadInterval=iu(this.loadInterval.bind(this),r,!1);else throw new Error("Invalid debounceMode: "+i)}onDomainChanged(t){var i;G(this,ds,t);const r=gt((i=this.params)==null?void 0:i.windowSize)??-1;t[1]-t[0]>r||this.callIfWindowsChanged(t,r,async s=>{await this.initializedPromise,this.loadInterval(s)})}reloadLastDomain(){const t=E(this,ds);G(this,ds,[0,0]),G(this,hs,[0,0]),this.onDomainChanged(t)}async loadInterval(t){}async discretizeAndLoad(t,r){E(this,fs).abort(),this.setLoadingStatus("loading"),G(this,fs,new AbortController);const i=E(this,fs).signal,s=this.genome.continuousToDiscreteChromosomeIntervals(t);try{const o=await Promise.all(s.map(async a=>r(a,i)));if(!i.aborted)return this.setLoadingStatus("complete"),o}catch(o){if(!i.aborted)throw this.setLoadingStatus("error",o.message),o}}callIfWindowsChanged(t,r,i){const s=[Math.max(Math.floor(t[0]/r)*r,0),Math.min(Math.ceil(t[1]/r)*r,this.genome.totalSize)],o=E(this,hs);(r!==E(this,la)||s[0]<o[0]||s[1]>o[1])&&(G(this,hs,s),G(this,la,r),i(s))}}fs=new WeakMap,hs=new WeakMap,ds=new WeakMap,la=new WeakMap;class s9 extends Ho{constructor(e,t){const r={channel:"x",windowSize:7e3,debounce:200,debounceMode:"window",...e};if(super(t,r.channel),this.params=r,!this.params.url)throw new Error("No URL provided for IndexedFastaSource");this.setupDebouncing(this.params),this.initializedPromise=new Promise(i=>{Promise.all([Promise.resolve().then(()=>LB),Promise.resolve().then(()=>_o)]).then(([{IndexedFasta:s},{RemoteFile:o}])=>{const a=c=>new o(Uo(c,this.view.getBaseUrl()));this.fasta=new s({fasta:a(this.params.url),fai:a(this.params.indexUrl??this.params.url+".fai")}),i()})})}get label(){return"bigWigSource"}async loadInterval(e){const t=await this.discretizeAndLoad(e,async(r,i)=>this.fasta.getSequence(r.chrom,r.startPos,r.endPos,{signal:i}).then(s=>{if(s!=null)return{chrom:r.chrom,start:r.startPos,sequence:s};console.log(`No sequence found for interval ${r.chrom}:${r.startPos}-${r.endPos}`)}));this.publishData([t.filter(r=>r!==void 0)])}}class o9 extends Ho{constructor(t,r){const i={pixelsPerBin:2,channel:"x",debounce:200,debounceMode:"window",...t},s=Bc(r.paramMediator,i,o=>{o.includes("url")?O(this,fa,wd).call(this).then(()=>this.reloadLastDomain()):o.includes("pixelsPerBin")&&this.reloadLastDomain()});super(r,s.channel);R(this,fa);R(this,ps,[]);R(this,ms);if(this.params=s,!this.params.url)throw new Error("No URL provided for BigWigSource");this.setupDebouncing(this.params),O(this,fa,wd).call(this)}get label(){return"bigWigSource"}async onDomainChanged(t){await this.initializedPromise;const r=this.scaleResolution.getAxisLength()||700,i=a9(t,r,E(this,ps)),s=Math.max(i*r,5e3);this.callIfWindowsChanged(t,s,o=>this.loadInterval(o,i))}async loadInterval(t,r){const i=.5/r/gt(this.params.pixelsPerBin),s=await this.discretizeAndLoad(t,(o,a)=>E(this,ms).getFeatures(o.chrom,o.startPos,o.endPos,{scale:i,signal:a}).then(c=>c.map(u=>({chrom:o.chrom,start:u.start,end:u.end,score:u.score}))));s&&this.publishData(s)}}ps=new WeakMap,ms=new WeakMap,fa=new WeakSet,wd=function(){return this.initializedPromise=new Promise((t,r)=>{Promise.all([Promise.resolve().then(()=>wb),Promise.resolve().then(()=>_o)]).then(([{BigWig:i},{RemoteFile:s}])=>{G(this,ms,new i({filehandle:new s(Uo(gt(this.params.url),this.view.getBaseUrl()))})),this.setLoadingStatus("loading"),E(this,ms).getHeader().then(o=>{G(this,ps,o.zoomLevels.map(a=>a.reductionLevel).reverse()),E(this,ps).push(1),this.setLoadingStatus("complete"),t()}).catch(o=>{this.load(),this.setLoadingStatus("error",`${gt(this.params.url)}: ${o.message}`),r(o)})})}),this.initializedPromise};function a9(n,e,t){const r=(n[1]-n[0])/e;return t.find(i=>i<r)??t.at(-1)}class c9 extends Ho{constructor(t,r){const i={channel:"x",windowSize:1e6,debounce:200,debounceMode:"window",...t},s=Bc(r.paramMediator,i,o=>{o.includes("url")?O(this,ha,vd).call(this).then(()=>this.reloadLastDomain()):o.includes("windowSize")&&this.reloadLastDomain()});super(r,s.channel);R(this,ha);Y(this,"parser");Y(this,"bbi");Y(this,"parseLine");if(this.params=s,!this.params.url)throw new Error("No URL provided for BigBedSource");this.setupDebouncing(this.params),O(this,ha,vd).call(this)}get label(){return"bigBedSource"}async loadInterval(t){const r=await this.discretizeAndLoad(t,async(i,s)=>this.bbi.getFeatures(i.chrom,i.startPos,i.endPos,{signal:s}).then(o=>o.map(a=>this.parseLine(i.chrom,a))));r&&this.publishData(r)}}ha=new WeakSet,vd=function(){return this.initializedPromise=new Promise((t,r)=>{Promise.all([Promise.resolve().then(()=>_k),Promise.resolve().then(()=>wb),Promise.resolve().then(()=>_o)]).then(([i,{BigBed:s},{RemoteFile:o}])=>{const a=i.default;this.bbi=new s({filehandle:new o(Uo(gt(this.params.url),this.view.getBaseUrl()))}),this.setLoadingStatus("loading"),this.bbi.getHeader().then(async c=>{this.parser=new a({autoSql:c.autoSql});try{const u=u9(this.parser);this.parseLine=(l,f)=>u(l,f.start,f.end,f.rest)}catch{this.parseLine=(l,f)=>this.parser.parseLine(`${l}	${f.start}	${f.end}	${f.rest}`)}this.setLoadingStatus("complete"),t()}).catch(c=>{this.load(),this.setLoadingStatus("error",`${gt(this.params.url)}: ${c.message}`),r(c)})})}),this.initializedPromise};function u9(n){const e=n.autoSql.fields.filter(x=>x.type).slice(3);let t=0,r="",i=0,s={};const o="	",a=o.charCodeAt(0),c=48,u=45;function l(){let x=r.indexOf(o,t);x<0&&(x=i);const A=r.substring(t,x);return t=x+1,A}function f(){let x=0,A=r.charCodeAt(t),w=1;A===u&&(w=-1,t++,A=r.charCodeAt(t));do{if(A===a){t++;break}x=x*10+A-c,A=r.charCodeAt(++t)}while(t<i);return x*w}const d=e.map(x=>`${JSON.stringify(x.name)}: ${x.isNumeric?"0":"emptyString"}`),h=new Function(`
         const emptyString = "";
         return function makeTemplate(chrom, chromStart, chromEnd) {
             return {
@@ -624,109 +624,103 @@ chrM	16299`};function gB(t){if(!(t in yb))throw new Error(`Unknown assembly: ${t
                 ${d.join(`,
 `)}
             }
-        };`)(),p=e.map(A=>{const S=A.type,E=JSON.stringify(A.name);if(["ubyte","int","uint"].includes(S))return`d[${E}] = parseInt();`;if(A.isNumeric)return`d[${E}] = Number(parseString());`;if(["char","string","lstring"].includes(S))return`d[${E}] = parseString();`;throw new Error("Unsupported type: "+S)}),y=Dk(p,50).map((A,S)=>Function("parseInt","parseString",`return function parseFieldChunk${S}(d) {
-            ${A.join(`
+        };`)(),p=e.map(x=>{const A=x.type,w=JSON.stringify(x.name);if(["ubyte","int","uint"].includes(A))return`d[${w}] = parseInt();`;if(x.isNumeric)return`d[${w}] = Number(parseString());`;if(["char","string","lstring"].includes(A))return`d[${w}] = parseString();`;throw new Error("Unsupported type: "+A)}),m=l9(p,50).map((x,A)=>Function("parseInt","parseString",`return function parseFieldChunk${A}(d) {
+            ${x.join(`
 `)}
-        }`)(f,u));function v(A){r=A,o=A.length,n=0}function b(A,S,E,I){v(I),i=h(A,S,E);for(const _ of y)_(i);return i}return b}function Dk(t,e){return Array.from({length:Math.ceil(t.length/e)},(n,r)=>t.slice(r*e,r*e+e))}class Bk extends Ta{constructor(n,r){const o={channel:"x",windowSize:2e4,debounce:200,debounceMode:"domain",...n};super(r,o.channel);he(this,Ni);Gt(this,"chrPrefixFixer",n=>n);if(this.params=o,!this.params.url)throw new Error("No URL provided for BamSource");this.setupDebouncing(this.params),this.initializedPromise=new Promise(i=>{Promise.all([Promise.resolve().then(()=>fM),Promise.resolve().then(()=>_a)]).then(([{BamFile:s},{RemoteFile:a}])=>{const c=l=>new a(Ca(l,this.view.getBaseUrl()));Ae(this,Ni,new s({bamFilehandle:c(this.params.url),baiFilehandle:c(this.params.indexUrl??this.params.url+".bai")})),j(this,Ni).getHeader().then(l=>{var d,h;const u=this.genome.hasChrPrefix(),f=(h=(d=j(this,Ni).indexToChr)==null?void 0:d[0])==null?void 0:h.refName.startsWith("chr");u&&!f?this.chrPrefixFixer=p=>p.replace("chr",""):!u&&f&&(this.chrPrefixFixer=p=>"chr"+p),i()})})})}get label(){return"bamSource"}async loadInterval(n){const r=await this.discretizeAndLoad(n,async(o,i)=>j(this,Ni).getRecordsForRange(this.chrPrefixFixer(o.chrom),o.startPos,o.endPos,{signal:i}).then(s=>s.map(a=>({chrom:o.chrom,start:a.start,end:a.end,name:a.name,cigar:a.CIGAR,mapq:a.mq,strand:a.strand===1?"+":"-"}))));r&&this.publishData(r)}}Ni=new WeakMap;class qb extends Ta{constructor(n,r){const o={channel:"x",windowSize:3e6,debounce:200,debounceMode:"domain",addChrPrefix:!1,...n};super(r,o.channel);he(this,is);if(this.params=o,!this.params.url)throw new Error("No URL provided for TabixSource");this.setupDebouncing(this.params),this.initializedPromise=new Promise(i=>{Promise.all([Promise.resolve().then(()=>vM),Promise.resolve().then(()=>_a)]).then(async([{TabixIndexedFile:s},{RemoteFile:a}])=>{const c=u=>new a(Ca(u,this.view.getBaseUrl()));Ae(this,is,new s({filehandle:c(this.params.url),tbiFilehandle:c(this.params.indexUrl??this.params.url+".tbi"),renameRefSeqs:this.params.addChrPrefix===!0?u=>"chr"+u:this.params.addChrPrefix?u=>this.params.addChrPrefix+u:void 0}));const l=await j(this,is).getHeader();await this._handleHeader(l),i()})})}async loadInterval(n){await this.initializedPromise;const r=await this.discretizeAndLoad(n,async(o,i)=>{const s=[];return await j(this,is).getLines(o.chrom,o.startPos,o.endPos,{lineCallback:a=>{s.push(a)},signal:i}),this._parseFeatures(s)});r&&this.publishData(r)}async _handleHeader(n){}_parseFeatures(n){return[]}}is=new WeakMap;class kk extends qb{constructor(){super(...arguments);he(this,tc)}get label(){return"gff3Source"}async _handleHeader(n){Ae(this,tc,(await Promise.resolve().then(()=>UM)).default)}_parseFeatures(n){var o;return(o=j(this,tc))==null?void 0:o.parseStringSync(n.join(`
-`),{parseSequences:!1})}}tc=new WeakMap;class _k extends qb{constructor(){super(...arguments);he(this,nc)}get label(){return"vcfSource"}async _handleHeader(n){const r=(await Promise.resolve().then(()=>VM)).default;Ae(this,nc,new r({header:n}))}_parseFeatures(n){return n.map(r=>{const o=j(this,nc).parseLine(r);return delete o.GENOTYPES,o.SAMPLES=o.SAMPLES(),o})}}nc=new WeakMap;function Rk(t,e){if(jb(t))return new mk(t,e);if(yk(t))return new bk(t,e);if(wk(t))return new xk(t,e);if(Fk(t))return Hk(t.lazy,e);throw new Error("Cannot figure out the data source type: "+JSON.stringify(t))}function Fk(t){return"lazy"in t}function Mk(t){return(t==null?void 0:t.type)=="axisTicks"}function Pk(t){return(t==null?void 0:t.type)=="axisGenome"}function Lk(t){return(t==null?void 0:t.type)=="indexedFasta"}function Ok(t){return(t==null?void 0:t.type)=="bigwig"}function Nk(t){return(t==null?void 0:t.type)=="bigbed"}function zk(t){return(t==null?void 0:t.type)=="bam"}function Uk(t){return(t==null?void 0:t.type)=="gff3"}function Gk(t){return(t==null?void 0:t.type)=="vcf"}function Hk(t,e){if(Mk(t))return new vk(t,e);if(Pk(t))return new Ak(t,e);if(Lk(t))return new Ek(t,e);if(Ok(t))return new Sk(t,e);if(Nk(t))return new Ik(t,e);if(zk(t))return new Bk(t,e);if(Uk(t))return new kk(t,e);if(Gk(t))return new _k(t,e);throw new Error("Cannot figure out the data source type: "+JSON.stringify(t))}function Vk(t){const e=Wb(t).filter(r=>typeof r=="string"),n=new Function("source","return { "+e.map(r=>JSON.stringify(r)).map(r=>`${r}: source[${r}]`).join(`,
-`)+" };");return n.properties=e,n}function Wb(t){let e=[];do e=e.concat(Object.keys(t)),t=Object.getPrototypeOf(t);while(t&&t!==Object.prototype);return Array.from(new Set(e))}class Wl extends yt{constructor(){super({type:"clone"});he(this,os);he(this,rc,n=>n);const n=r=>{const o=Wb(r);(!j(this,os)||!Uc(o,j(this,os)))&&(Ae(this,os,o),Ae(this,rc,Vk(r)));const i=j(this,rc);this.handle=s=>this._propagate(i(s)),this.handle(r)};this.handle=n,this.beginBatch=r=>{Lm(r)&&(this.handle=n),super.beginBatch(r)}}get behavior(){return On}}os=new WeakMap,rc=new WeakMap;function jk(t){return"name"in t}class Yb extends Ao{constructor(n,r,o){super(r);he(this,ic);this.provider=o,this.params=n}get identifier(){return this.params.name}get label(){return"namedSource"}updateDynamicData(n){Ae(this,ic,n),this.loadSynchronously()}loadSynchronously(){const n=j(this,ic)??this.provider(this.params.name)??[];let r=o=>o;if(Array.isArray(n))n.length>0&&(r=Hb(n[0]));else throw new Error(`Named data "${this.params.name}" is not an array!`);this.reset(),this.beginBatch({type:"file"});for(const o of n)this._propagate(r(o));this.complete()}async load(){this.loadSynchronously()}}ic=new WeakMap;class Qb{constructor(){this._dataSourcesByHost=new Map,this._collectorsByHost=new Map,this._observers=new Map}get dataSources(){return[...new Set(this._dataSourcesByHost.values()).values()]}get collectors(){return[...this._collectorsByHost.values()]}addObserver(e,n){let r=this._observers.get(n);r||(r=[],this._observers.set(n,r)),r.push(e)}_relayObserverCallback(e,n){const r=this._observers.get(n);if(r)for(const o of r)o(e)}addDataSource(e,n){this._dataSourcesByHost.set(n,e)}findDataSourceByKey(e){return this._dataSourcesByHost.get(e)}findNamedDataSource(e){let n,r=[];for(const[o,i]of this._dataSourcesByHost.entries())if(i instanceof Yb&&e==i.identifier){if(n&&n!==i)throw new Error(`Found multiple instances of named data: ${e}. Data flow optimization is broken (it's a bug).`);n=i,r.push(o)}if(n)return{dataSource:n,hosts:r}}addCollector(e,n){this._collectorsByHost.set(n,e),e.observers.push(r=>this._relayObserverCallback(r,n))}findCollectorByKey(e){return this._collectorsByHost.get(e)}initialize(){for(const e of this.dataSources)e.visit(n=>n.initialize())}}function qk(t,e){const n=new Map,r=[];for(const o of t)n.set(o,{ref:o,children:[]});for(const o of n.values()){const i=n.get(e(o.ref));i?i.children.push(o):r.push(o)}return r}function Zb(t,e,n){var o,i;const r=(o=e.preOrder)==null?void 0:o.call(e,t);if(r)return r;for(const s of n(t)){const a=Zb(s,e,n);if(a==="stop")return a}return(i=e.postOrder)==null?void 0:i.call(e,t)}function Wk(t,e){return Zb(t,e,n=>n.children)}function Yk(t,e){const n=[],r=[];let o;const i=e??new Qb,s=[];function a(h,p=()=>{}){if(!o)throw p()||new Error("Cannot append data flow node, no parent exist!");return o.addChild(h),o=h,n.push(h),h}function c(h,p){return a(h,()=>new Error("Cannot append a transform because no (inherited) data are available! 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a_({requestAnimationFrame:n=>this.requestTransition(n),...e})}}function pd(t,e,n,r,o){let i=0,s=!0,a=structuredClone(o),c=a;function l(d,h,p,y){return h+(d-h)*Math.pow(2,-p/y)}function u(d){if(s)return;const h=d-i;i=d;for(const y of Object.keys(c))a[y]=l(a[y],c[y],h,n);e(a);let p=-1/0;for(const y of Object.keys(c))p=Math.max(p,Math.abs(c[y]-a[y]));p<r?(a=c,e(a),s=!0,p!=0&&t.requestRender()):t.requestTransition(y=>u(y))}function f(d){c=d,s&&(s=!1,i=+document.timeline.currentTime,u(i))}return f.stop=()=>{s=!0},f}class l_{constructor(e){this.genomes=new Map,this.baseUrl=e}async initialize(e){const n=new yB(e);return this.genomes.set(n.name,n),Promise.all([...this.genomes.values()].map(r=>r.load(this.baseUrl)))}getGenome(e){if(!this.genomes.size)throw new Error("No genomes have been configured!");if(e){const n=this.genomes.get(e);if(!n)throw new Error(`No genome with the name ${e} has been configured!`);return n}else{if(this.genomes.size>1)throw new Error("Cannot pick a default genome! More than one have been configured!");return this.genomes.values().next().value}}}const 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",f_={thin:100,light:300,regular:400,normal:400,medium:500,bold:700,black:900};class h_{constructor(e){this._webGLHelper=e,this.fontRepository="https://raw.githubusercontent.com/etiennepinchon/aframe-fonts/master/fonts/",this._fonts=new Yn([],JSON.stringify),this._metadataPromises=new Map,this._fontPromises=new Map,this._promises=[],this._defaultFontEntry={metrics:jf(zb),texture:e?this._createTextureNow(u_):void 0}}async waitUntilReady(){await Promise.all(this._promises)}getFont(e,n="normal",r="regular"){if(rt(r)&&(r=f_[r.toLowerCase()],!r))throw new Error("Unknown font weight: "+r);const o={family:e,style:n,weight:r};let i=this._fonts.get(o);return i||(i={metrics:void 0,texture:void 0},this._fonts.set(o,i),this._promises.push(this._loadFontEntry(i,o))),i}async _loadFontEntry(e,n){try{const r=await this._loadMetadata(n.family),o=p_(r,n),i=this.fontRepository+Jb(n.family)+"/"+o.replace(/\.\w+/,""),s=this._createTexture(i+".png"),a=this._loadFont(i+".json");e.texture=await s,e.metrics=await a}catch{console.warn(`Cannot load font: "${n.family}". Using the embedded default font.`),e.metrics=this._defaultFontEntry.metrics,e.texture=this._defaultFontEntry.texture}}_loadFont(e){let n=this._fontPromises.get(e);return n||(n=fetch(e).then(r=>{if(!r.ok)throw new Error("Could not load font: "+r.status);return r}).then(r=>r.json()).then(r=>jf(r)),this._fontPromises.set(e,n)),n}_loadMetadata(e){const n=Jb(e);let r=this._metadataPromises.get(n);if(!r){const o=this.fontRepository+n+"/METADATA.pb";r=fetch(o).then(i=>{if(!i.ok)throw new Error("Could not load font metadata. Response status: "+i.status+", url: "+o);return i}).then(i=>i.text()).then(i=>d_(i)).catch(i=>{console.warn(i.message)}),this._metadataPromises.set(n,r)}return r}getDefaultFont(){return this._defaultFontEntry}_createTexture(e){const n=this._webGLHelper.gl;return new Promise((r,o)=>{Ys(n,{src:e,min:n.LINEAR},(i,s,a)=>{i?o(i):r(s)})})}_createTextureNow(e){const n=this._webGLHelper.gl;let r;const o=new Promise((i,s)=>{r=Ys(n,{src:e,min:n.LINEAR},(a,c,l)=>{a?s(a):i(c)})});return this._promises.push(o),r}}function Jb(t){return t.toLowerCase().replaceAll(/[^\w]/g,"")}function d_(t){const e=t.split(`
-`),n=[];let r;for(const o of e)if(o.startsWith("fonts {")&&(r={name:void 0,style:void 0,weight:void 0,filename:void 0,post_script_name:void 0,full_name:void 0,copyright:void 0}),o.startsWith("}")&&(n.push(r),r=void 0),r){let i=o.match(/^\s*([A-Za-z_]+):[ ]?"(.*)"$/);if(i){const s=i[1];r[s]=i[2]}if(i=o.match(/^\s*([A-Za-z_]+):[ ]?(\d+)$/),i){const s=i[1];r[s]=+i[2]}}return n}function p_(t,e){let n,r=Number.POSITIVE_INFINITY;for(const o of t)if(e.family.localeCompare(o.name,void 0,{sensitivity:"accent"})==0&&e.style==o.style){const i=Math.abs(e.weight-o.weight);i<r&&(r=i,n=o)}return n==null?void 0:n.filename}function g_(t,e){const n=[];let r;for(const o of t.split(`
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Math.sqrt(this.x**2+this.y**2)}equals(e){return e?e===this||e.x===this.x&&e.y===this.y:!1}}const Q9=n=>new Promise(e=>setTimeout(e,n));function W9(n){const e=n.requestAnimationFrame||window.requestAnimationFrame,t=n.signal,r=()=>new Promise((i,s)=>{if(t!=null&&t.aborted)return s("aborted");const o=performance.now(),a=o+(n.duration||1e3),c=typeof n.from=="number"?n.from:0,u=typeof n.to=="number"?n.to:1,l=n.easingFunction||(m=>m),f=m=>(m-o)/(a-o),d=m=>m*(u-c)+c,h=m=>Math.max(0,Math.min(1,m)),p=m=>{t!=null&&t.aborted?s("aborted"):(n.onUpdate(d(l(h(f(m))))),m<a?e(p):(n.onUpdate(d(l(1))),i()))};e(p)});return n.delay?t!=null&&t.aborted?Promise.reject("aborted"):Q9(n.delay).then(r):r()}class q9{constructor(e){this._renderCallback=e,this._renderRequested=!1,this._warn=!1,this.transitions=[]}requestTransition(e){this.cancelTransition(e),this.transitions.push(e),this.requestRender()}cancelTransition(e){const t=this.transitions.indexOf(e);t>=0&&this.transitions.splice(t,1)}requestRender(){this._renderRequested?this._warn&&console.warn("Render already requested!"):(this._renderRequested=!0,window.requestAnimationFrame(e=>{this._renderRequested=!1;const t=this.transitions;this.transitions=[];let r;for(;r=t.shift();)r(e);this._renderCallback(e)}))}transition(e){return W9({requestAnimationFrame:t=>this.requestTransition(t),...e})}}function yh(n,e,t,r,i){let s=0,o=!0,a=structuredClone(i),c=a;function u(d,h,p,m){return h+(d-h)*Math.pow(2,-p/m)}function l(d){if(o)return;const h=d-s;s=d;for(const m of Object.keys(c))a[m]=u(a[m],c[m],h,t);e(a);let p=-1/0;for(const m of Object.keys(c))p=Math.max(p,Math.abs(c[m]-a[m]));p<r?(a=c,e(a),o=!0,p!=0&&n.requestRender()):n.requestTransition(m=>l(m))}function f(d){c=d,o&&(o=!1,s=+document.timeline.currentTime,l(s))}return f.stop=()=>{o=!0},f}class Y9{constructor(e){this.genomes=new Map,this.baseUrl=e}async initialize(e){const t=new XD(e);return this.genomes.set(t.name,t),Promise.all([...this.genomes.values()].map(r=>r.load(this.baseUrl)))}getGenome(e){if(!this.genomes.size)throw new Error("No genomes have been configured!");if(e){const t=this.genomes.get(e);if(!t)throw new Error(`No genome with the name ${e} has been configured!`);return t}else{if(this.genomes.size>1)throw new Error("Cannot pick a default genome! More than one have been configured!");return this.genomes.values().next().value}}}const 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",Z9={thin:100,light:300,regular:400,normal:400,medium:500,bold:700,black:900};class K9{constructor(e){this._webGLHelper=e,this.fontRepository="https://raw.githubusercontent.com/etiennepinchon/aframe-fonts/master/fonts/",this._fonts=new tn([],JSON.stringify),this._metadataPromises=new Map,this._fontPromises=new Map,this._promises=[],this._defaultFontEntry={metrics:Ql(dy),texture:e?this._createTextureNow(X9):void 0}}async waitUntilReady(){await Promise.all(this._promises)}getFont(e,t="normal",r="regular"){if(me(r)&&(r=Z9[r.toLowerCase()],!r))throw new Error("Unknown font weight: "+r);const i={family:e,style:t,weight:r};let s=this._fonts.get(i);return s||(s={metrics:void 0,texture:void 0},this._fonts.set(i,s),this._promises.push(this._loadFontEntry(s,i))),s}async _loadFontEntry(e,t){try{const r=await this._loadMetadata(t.family),i=$9(r,t),s=this.fontRepository+Dy(t.family)+"/"+i.replace(/\.\w+/,""),o=this._createTexture(s+".png"),a=this._loadFont(s+".json");e.texture=await o,e.metrics=await a}catch{console.warn(`Cannot load font: "${t.family}". Using the embedded default font.`),e.metrics=this._defaultFontEntry.metrics,e.texture=this._defaultFontEntry.texture}}_loadFont(e){let t=this._fontPromises.get(e);return t||(t=fetch(e).then(r=>{if(!r.ok)throw new Error("Could not load font: "+r.status);return r}).then(r=>r.json()).then(r=>Ql(r)),this._fontPromises.set(e,t)),t}_loadMetadata(e){const t=Dy(e);let r=this._metadataPromises.get(t);if(!r){const i=this.fontRepository+t+"/METADATA.pb";r=fetch(i).then(s=>{if(!s.ok)throw new Error("Could not load font metadata. Response status: "+s.status+", url: "+i);return s}).then(s=>s.text()).then(s=>J9(s)).catch(s=>{console.warn(s.message)}),this._metadataPromises.set(t,r)}return r}getDefaultFont(){return this._defaultFontEntry}_createTexture(e){const t=this._webGLHelper.gl;return new Promise((r,i)=>{oo(t,{src:e,min:t.LINEAR},(s,o,a)=>{s?i(s):r(o)})})}_createTextureNow(e){const t=this._webGLHelper.gl;let r;const i=new Promise((s,o)=>{r=oo(t,{src:e,min:t.LINEAR},(a,c,u)=>{a?o(a):s(c)})});return this._promises.push(i),r}}function Dy(n){return n.toLowerCase().replaceAll(/[^\w]/g,"")}function J9(n){const e=n.split(`
+`),t=[];let r;for(const i of e)if(i.startsWith("fonts {")&&(r={name:void 0,style:void 0,weight:void 0,filename:void 0,post_script_name:void 0,full_name:void 0,copyright:void 0}),i.startsWith("}")&&(t.push(r),r=void 0),r){let s=i.match(/^\s*([A-Za-z_]+):[ ]?"(.*)"$/);if(s){const o=s[1];r[o]=s[2]}if(s=i.match(/^\s*([A-Za-z_]+):[ ]?(\d+)$/),s){const o=s[1];r[o]=+s[2]}}return t}function $9(n,e){let t,r=Number.POSITIVE_INFINITY;for(const i of n)if(e.family.localeCompare(i.name,void 0,{sensitivity:"accent"})==0&&e.style==i.style){const s=Math.abs(e.weight-i.weight);s<r&&(r=s,t=i)}return t==null?void 0:t.filename}function eT(n,e){const t=[];let r;for(const i of n.split(`
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             <div class="title">
-                <strong>${i.name}</strong>
-                ${i.description}
+                <strong>${s.name}</strong>
+                ${s.description}
             </div>
-            <p class="summary">${i.summary}</p>
+            <p class="summary">${s.summary}</p>
             <p class="source">Source: NCBI RefSeq Gene</p>
-        `):null}async function x_(t){const e={mode:"cors"},n=new URL("https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi");n.search=new URLSearchParams({db:"gene",term:E_(t),sort:"relevance",retmax:"1",retmode:"json"}).toString();const o=(await fetch(n.toString(),e).then(i=>i.json())).esearchresult.idlist[0];if(o){const i=new URL("https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi");return i.search=new URLSearchParams({db:"gene",id:o,retmode:"json"}).toString(),(await fetch(i.toString(),e).then(c=>c.json())).result[o]}else return null}const v_=ql(x_,500);function A_(t){return v_(t)}function E_(t){return Object.entries(t).filter(([e,n])=>n&&n.length>0).map(([e,n])=>`("${n}"[${e}])`).join(" AND ")}const S_=Dt(".4~r"),C_=Dt(".4~e");function e2(t){return t==null?ot` <span class="na">NA</span> `:rt(t)?t.substring(0,30):Number.isInteger(t)?""+t:Ht(t)?Math.abs(t)>Math.pow(10,8)||Math.abs(t)<Math.pow(10,-8)?C_(t):S_(t):ps(t)?t?"True":"False":_t(t)?ot`${t.map((e,n)=>[e2(e),n<t.length-1?", ":pt])}`:"?"+typeof t+" "+t}async function I_(t,e,n){const r=(l,u)=>{var f;for(const[d,h]of Object.entries(e.encoders))if((f=h==null?void 0:h.dataAccessor)!=null&&f.fields.includes(l))switch(d){case"color":case"fill":case"stroke":return ot`
+        `):null}async function sT(n){const e={mode:"cors"},t=new URL("https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi");t.search=new URLSearchParams({db:"gene",term:cT(n),sort:"relevance",retmax:"1",retmode:"json"}).toString();const i=(await fetch(t.toString(),e).then(s=>s.json())).esearchresult.idlist[0];if(i){const s=new URL("https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi");return s.search=new URLSearchParams({db:"gene",id:i,retmode:"json"}).toString(),(await fetch(s.toString(),e).then(c=>c.json())).result[i]}else return null}const oT=iu(sT,500);function aT(n){return oT(n)}function cT(n){return Object.entries(n).filter(([e,t])=>t&&t.length>0).map(([e,t])=>`("${t}"[${e}])`).join(" AND ")}const uT=Le(".4~r"),lT=Le(".4~e");function Ty(n){return n==null?ye` <span class="na">NA</span> `:me(n)?n.substring(0,30):Number.isInteger(n)?""+n:Ze(n)?Math.abs(n)>Math.pow(10,8)||Math.abs(n)<Math.pow(10,-8)?lT(n):uT(n):Is(n)?n?"True":"False":Ue(n)?ye`${n.map((e,t)=>[Ty(e),t<n.length-1?", ":Ee])}`:"?"+typeof n+" "+n}async function fT(n,e,t){const r=(u,l)=>{var f;for(const[d,h]of Object.entries(e.encoders))if((f=h==null?void 0:h.dataAccessor)!=null&&f.fields.includes(u))switch(d){case"color":case"fill":case"stroke":return ye`
                             <span
                                 class="color-legend"
-                                style=${`background-color: ${h(u)}`}
+                                style=${`background-color: ${h(l)}`}
                             ></span>
-                        `}return""},o=(l,u)=>{const f=l.filter(([d,h])=>!d.startsWith("_"));if(f.length!==0)return f.map(([d,h])=>h!==null&&typeof h=="object"&&!Array.isArray(h)?ot`${o(Object.entries(h),(u||"")+d+".")}`:ot`
+                        `}return""},i=(u,l)=>{const f=u.filter(([d,h])=>!d.startsWith("_"));if(f.length!==0)return f.map(([d,h])=>h!==null&&typeof h=="object"&&!Array.isArray(h)?ye`${i(Object.entries(h),(l||"")+d+".")}`:ye`
                       <tr>
-                          <th>${u}${d}</th>
-                          <td>${e2(h)} ${r(d,t)}</td>
+                          <th>${l}${d}</th>
+                          <td>${Ty(h)} ${r(d,n)}</td>
                       </tr>
-                  `)},i=o(Object.entries(t));if(!i)return;const s=ot`
+                  `)},s=i(Object.entries(n));if(!s)return;const o=ye`
         <table class="attributes">
-            ${i}
+            ${s}
         </table>
-    `,a=e.unitView.getTitleText(),c=a?ot`
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               <div class="title">
                   <strong>${a}</strong>
               </div>
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Promise.all(this.spec.layer.map((n,r)=>this.context.createOrImportView(n,this,this,"grid"+r,o=>{if(!xd(o)&&!wd(o))throw new Pr("LayerView accepts only unit or layer specs as children!",this)}))))}get children(){return j(this,cr).slice()}*[Symbol.iterator](){for(const n of j(this,cr))yield n}render(n,r,o={}){if(super.render(n,r,o),!!this.isConfiguredVisible()){n.pushView(this,r);for(const i of j(this,cr))i.render(n,r,o);n.popView(this)}}propagateInteractionEvent(n){this.handleInteractionEvent(void 0,n,!0);for(let r=j(this,cr).length-1;r>=0;r--)if(j(this,cr)[r].propagateInteractionEvent(n),n.stopped)return;this.handleInteractionEvent(void 0,n,!1)}}cr=new WeakMap;class t2{constructor(e,n){this.n=e,this.maxCols=n??1/0}get nRows(){return this.maxCols==1/0?1:Math.ceil(this.n/this.maxCols)}get nCols(){return Math.min(this.n,this.maxCols)}get rowIndices(){const e=[],n=this.nCols,r=this.nRows;for(let o=0;o<r;o++){const i=[];e.push(i);for(let s=0;s<n;s++){const a=o*n+s;a<this.n&&i.push(a)}}return e}get colIndices(){const e=[],n=this.nCols,r=this.nRows;for(let o=0;o<n;o++){const i=[];e.push(i);for(let s=0;s<r;s++){const a=s*n+o;a<this.n&&i.push(a)}}return e}getCellIndex(e,n){let r=0;if(this.maxCols==1/0)r=n==0?e:void 0;else{if(e>=this.maxCols)return;r=n*this.nCols+e}return r<this.n?r:void 0}getCellCoords(e){if(!(e<0||e>=this.n))return[e%this.nCols,Math.floor(e/this.nCols)]}}const T_="chromosome_ticks_and_labels",D_={x:"width",y:"height"};function gd(t){return t=="x"?"y":"x"}const Yl={x:["bottom","top"],y:["left","right"]},md=Object.fromEntries(Object.entries(Yl).map(([t,e])=>e.map(n=>[n,t])).flat(1));function Or(t){return md[t]}class n2 extends Eo{constructor(e,n,r,o,i,s){const a=n=="locus",c={...a?k_:r2,...B_(n,e),...e};super(a?__(c,n):i2(c,n),r,o,i,`axis_${e.orient}`,{blockEncodingInheritance:!0,contributesToScaleDomain:!1,...s}),this.axisProps=c}getSize(){const e={px:this.getPerpendicularSize()},n={grow:1};return md[this.axisProps.orient]=="x"?new Lr(n,e):new Lr(e,n)}getPerpendicularSize(){return yd(this.axisProps)}isPickingSupported(){return!1}}function yd(t){const e=Or(t.orient);let n=t.ticks&&t.tickSize||0;return t.labels&&(n+=t.labelPadding,e=="x"?n+=t.labelFontSize:n+=30),t.title&&(n+=t.titlePadding+t.titleFontSize),n=Math.min(t.maxExtent||1/0,Math.max(t.minExtent||0,n)),n}const r2={values:null,minExtent:20,maxExtent:1/0,offset:0,domain:!0,domainWidth:1,domainColor:"gray",domainDash:null,domainDashOffset:0,domainCap:"square",ticks:!0,tickSize:5,tickWidth:1,tickColor:"gray",tickDash:null,tickDashOffset:0,tickCap:"square",tickCount:null,tickMinStep:null,labels:!0,labelAlign:"center",labelBaseline:"middle",labelPadding:4,labelFontSize:10,labelLimit:180,labelColor:"black",format:null,titleColor:"black",titleFont:"sans-serif",titleFontSize:10,titlePadding:3};function B_(t,e){const n=e.orient,r=t=="nominal"||t=="ordinal";let o="center",i="middle",s=e.labelAngle??((n=="top"||n=="bottom")&&r?-90:0);switch(n){case"left":o="right";break;case"right":o="left";break;case"top":case"bottom":Math.abs(s)>30?(o=s>0==(n=="bottom")?"left":"right",i="middle"):i=n=="top"?"alphabetic":"top";break}return{labelAlign:o,labelAngle:s,labelBaseline:i}}function i2(t,e){const n={...t,extent:yd(t)},r=Or(n.orient),o=gd(r),i=n.orient=="bottom"||n.orient=="right"?1:-1,s=n.orient=="bottom"||n.orient=="left"?1:0,a=()=>({name:"domain",data:{values:[{}]},mark:{type:"rule",clip:!1,strokeDash:n.domainDash,strokeCap:n.domainCap,color:n.domainColor,[o]:s,size:n.domainWidth}}),c=()=>({name:"labels",mark:{type:"text",clip:!1,align:n.labelAlign,angle:n.labelAngle,baseline:n.labelBaseline,[o+"Offset"]:(n.tickSize+n.labelPadding)*i,[o]:s,size:n.labelFontSize,color:n.labelColor,minBufferSize:1500},encoding:{[r]:{field:"value",type:e},text:{field:"label"}}}),l=()=>({name:"ticks",mark:{type:"rule",clip:!1,strokeDash:n.tickDash,strokeCap:n.tickCap,color:n.tickColor,size:n.tickWidth,minBufferSize:300},encoding:{[o]:{value:s},[o+"2"]:{value:s-n.tickSize/n.extent*(s?1:-1)}}}),u=()=>({name:"title",data:{values:[{}]},mark:{type:"text",clip:!1,align:"center",baseline:n.orient=="bottom"?"bottom":"top",angle:[0,90,0,-90][["top","right","bottom","left"].indexOf(n.orient)],text:n.title,color:n.titleColor,[r]:.5,[o]:1-s}}),f=()=>{const h={name:"ticks_and_labels",encoding:{[r]:{field:"value",type:e}},layer:[]};return n.ticks&&h.layer.push(l()),n.labels&&h.layer.push(c()),h},d={resolve:{scale:{[r]:"forced"}},[D_[gd(r)]]:n.extent,data:{lazy:{type:"axisTicks",channel:r,axis:t}},layer:[]};return n.domain&&d.layer.push(a()),(n.ticks||n.labels)&&d.layer.push(f()),n.title&&d.layer.push(u()),d}const k_={...r2,chromTicks:!0,chromTickSize:18,chromTickWidth:1,chromTickColor:"#989898",chromTickDash:[4,2],chromTickDashOffset:1,chromLabels:!0,chromLabelFontSize:13,chromLabelFontWeight:"normal",chromLabelFontStyle:"normal",chromLabelColor:"black",chromLabelAlign:"left",chromLabelPadding:7};function __(t,e){const n={...t,extent:yd(t)},r=Or(n.orient),o=gd(r),i=n.orient=="bottom"||n.orient=="left"?1:0,s=()=>({name:"chromosome_ticks",mark:{type:"rule",strokeDash:t.chromTickDash,strokeDashOffset:t.chromTickDashOffset,[o]:i,[o+"2"]:i-n.chromTickSize/n.extent*(i?1:-1),color:t.chromTickColor,size:n.chromTickWidth}}),a=()=>{let u;switch(n.orient){case"top":u={y:0,angle:0,paddingX:4,dy:-n.chromLabelPadding,viewportEdgeFadeWidthLeft:20,viewportEdgeFadeWidthRight:20,viewportEdgeFadeDistanceRight:-10,viewportEdgeFadeDistanceLeft:-20};break;case"bottom":u={y:1,angle:0,paddingX:4,dy:n.chromLabelPadding+n.chromLabelFontSize*.73,viewportEdgeFadeWidthLeft:20,viewportEdgeFadeWidthRight:20,viewportEdgeFadeDistanceRight:-10,viewportEdgeFadeDistanceLeft:-20};break;case"left":u={x:1,angle:-90,paddingY:4,dy:-n.chromLabelPadding,viewportEdgeFadeWidthBottom:20,viewportEdgeFadeWidthTop:20,viewportEdgeFadeDistanceBottom:-20,viewportEdgeFadeDistanceTop:-10};break;case"right":u={x:0,angle:90,align:"right",paddingY:4,dy:-n.chromLabelPadding};break;default:u={}}return{name:"chromosome_labels",mark:{type:"text",size:n.chromLabelFontSize,font:n.chromLabelFont,fontWeight:n.chromLabelFontWeight,fontStyle:n.chromLabelFontStyle,color:n.chromLabelColor,align:t.chromLabelAlign,baseline:"alphabetic",clip:!1,...u},encoding:{[r+"2"]:{field:"continuousEnd",type:e},text:{field:"name"}}}};let c;switch(n.orient){case"bottom":case"top":c={};break;case"left":c={labelAngle:-90,labelAlign:"center",labelPadding:6};break;case"right":c={labelAngle:90,labelAlign:"center",labelPadding:6};break;default:c={}}const l=i2({...t,...c},e);if(t.chromTicks||t.chromLabels){const u={name:T_,data:{lazy:{type:"axisGenome",channel:Or(n.orient)}},encoding:{[r]:{field:"continuousStart",type:e,band:0}},layer:[]};if(t.chromTicks&&u.layer.push(s()),t.chromLabels){u.layer.push(a());let f;l.layer.filter(d=>d.name=="ticks_and_labels").forEach(d=>d.layer.filter(h=>h.name=="labels").forEach(h=>{f=h.mark})),f&&(n.orient=="top"||n.orient=="bottom"?(f.viewportEdgeFadeWidthLeft=30,f.viewportEdgeFadeDistanceLeft=40):(f.viewportEdgeFadeWidthBottom=30,f.viewportEdgeFadeDistanceBottom=40))}l.layer.push(u)}return l}class R_{constructor(e){he(this,zi);he(this,jr,0);he(this,qr,0);Ae(this,zi,new Array(e))}push(e){j(this,zi)[j(this,jr)]=e,Ae(this,jr,(j(this,jr)+1)%this.size),Ae(this,qr,Math.min(j(this,qr)+1,this.size))}get(){const e=j(this,zi);return j(this,qr)<this.size?e.slice(0,j(this,qr)):e.slice(j(this,jr),this.size).concat(e.slice(0,j(this,jr)))}get size(){return j(this,zi).length}get length(){return j(this,qr)}}zi=new WeakMap,jr=new WeakMap,qr=new WeakMap;let Ci,o2=0;function s2(){return performance.now()-o2<50}function F_(t){return function(...e){o2=performance.now(),t(...e)}}function M_(t,e,n,r,o){if(n=F_(n),t.type=="wheel"){t.uiEvent.preventDefault();const i=t.uiEvent,s=i.deltaMode?120:1;if(!i.deltaX&&!i.deltaY)return;Ci==null||Ci.stop();let{x:a,y:c}=t.point;if(r){const l=r.mark.encoders;l.x&&!l.x2&&!l.x.constant&&(a=+l.x(r.datum)*e.width+e.x),l.y&&!l.y2&&!l.y.constant&&(c=(1-+l.y(r.datum))*e.height+e.y)}Math.abs(i.deltaX)<Math.abs(i.deltaY)?n({x:a,y:c,xDelta:0,yDelta:0,zDelta:i.deltaY*s/300}):n({x:a,y:c,xDelta:-i.deltaX*s,yDelta:0,zDelta:0})}else if(t.type=="mousedown"&&t.mouseEvent.button===0){Ci&&Ci.stop();const i=new R_(30),s=t.mouseEvent;s.preventDefault();let a=Xt.fromMouseEvent(s);const c=f=>{const d=Xt.fromMouseEvent(f);i.push({point:d,timestamp:performance.now()});const h=d.subtract(a);n({x:a.x,y:a.y,xDelta:h.x,yDelta:h.y,zDelta:0}),a=d},l=()=>{const d=performance.now(),h=i.get().filter(S=>d-S.timestamp<160);if(h.length<5||!o||P_(h))return;const p=h.at(-1),y=h[0],v=p.point.subtract(y.point).multiply(1/(p.timestamp-y.timestamp));let b=a.x,A=a.y;Ci=pd(o,S=>{n({x:S.x,y:S.y,xDelta:b-S.x,yDelta:A-S.y,zDelta:0}),b=S.x,A=S.y},150,.5,{x:b,y:A}),Ci({x:a.x-v.x*250,y:a.y-v.y*250})},u=()=>{document.removeEventListener("mousemove",c),document.removeEventListener("mouseup",u),l()};document.addEventListener("mouseup",u,!1),document.addEventListener("mousemove",c,!1)}}function P_(t){const e=t[Math.floor(t.length/2)],n=e.point.subtract(t[0].point).multiply(e.timestamp-t[0].timestamp),r=t.at(-1).point.subtract(e.point).multiply(t.at(-1).timestamp-e.timestamp),o=n.length;return r.length/o<.4}class L_ extends Eo{constructor(e,n,r,o,i,s){const c={...n=="locus"?O_:a2,...e};super(G_(c,n),r,o,i,`axisGrid_${e.orient}`,{blockEncodingInheritance:!0,contributesToScaleDomain:!1,...s}),this.axisProps=c}getOrient(){return this.axisProps.orient}isPickingSupported(){return!1}}const a2={values:null,grid:!1,gridCap:"butt",gridColor:"lightgray",gridDash:null,gridOpacity:1,gridWidth:1,tickCount:null,tickMinStep:null},O_={...a2,chromGrid:!1,chromGridCap:"butt",chromGridColor:"gray",chromGridDash:[1,5],chromGridOpacity:1,chromGridWidth:1};function N_(t,e){const n=t,r=Or(n.orient);return{name:"grid_lines",data:{lazy:{type:"axisTicks",channel:r,axis:t}},mark:{type:"rule",strokeDash:n.gridDash,strokeCap:n.gridCap,color:n.gridColor,size:n.gridWidth,opacity:n.gridOpacity,minBufferSize:300},encoding:{[r]:{field:"value",type:e}}}}function z_(t,e){const n=t,r=Or(n.orient);return{name:"chromosome_lines",data:{lazy:{type:"axisGenome",channel:r}},mark:{type:"rule",strokeDash:n.chromGridDash,strokeCap:n.chromGridCap,color:n.chromGridColor,size:n.chromGridWidth,opacity:n.chromGridOpacity},encoding:{[r]:{field:"continuousStart",type:e,band:0}}}}function U_(t,e){const n=t,r=Or(n.orient);return{name:"chromosome_fill",data:{lazy:{type:"axisGenome",channel:r}},mark:{type:"rect"},encoding:{[r]:{field:"continuousStart",type:e,band:0},[r+"2"]:{field:"continuousEnd",band:0},fill:{field:"odd",type:"nominal",scale:{domain:[!1,!0],range:[n.chromGridFillEven??"white",n.chromGridFillOdd??"white"]}},opacity:{field:"odd",type:"nominal",scale:{type:"ordinal",domain:[!1,!0],range:[n.chromGridFillEven?1:0,n.chromGridFillOdd?1:0]}}}}}function G_(t,e){const n={...t},r=[];return n.chromGrid&&(n.chromGridFillOdd||n.chromGridFillEven)&&r.push(U_(n,e)),n.chromGrid&&n.chromGridOpacity>0&&r.push(z_(n,e)),n.grid&&n.gridOpacity>0&&r.push(N_(n,e)),{name:"grid_layers",configurableVisibility:!1,resolve:{scale:{[Or(t.orient)]:"forced",fill:"independent",opacity:"independent"}},layer:r}}const c2={anchor:"middle",frame:"group",offset:10,orient:"top",align:void 0,angle:0,baseline:"alphabetic",dx:0,dy:0,color:void 0,font:void 0,fontSize:12,fontStyle:"normal",fontWeight:"normal"},H_={orient:"left",anchor:"middle",align:"right",baseline:"middle",angle:0,fontSize:12},V_={orient:"top",anchor:"start",align:"left",baseline:"top",offset:-10,dx:10,fontSize:12},j_={start:0,middle:.5,end:1},q_={start:"left",middle:"center",end:"right"};function W_(t){if(!t)return;const e=rt(t)?{text:t}:t;if(!e.text||e.orient=="none")return;const n={"track-title":H_,overlay:V_}[e.style]??{},r={...c2,...n,...e};let o={},i={x:0,y:0};const s=j_[r.anchor??"middle"];switch(r.orient){case"top":i={x:s,y:1},o={baseline:"alphabetic",angle:0};break;case"right":i={x:1,y:1-s},o={baseline:"alphabetic",angle:90};break;case"bottom":i={x:s,y:0},o={baseline:"top",angle:0};break;case"left":i={x:0,y:s},o={baseline:"alphabetic",angle:-90};break}const a={...c2,...o,...n,...e},c={xOffset:0,yOffset:0};switch(r.orient){case"top":c.yOffset=-a.offset;break;case"right":c.xOffset=a.offset;break;case"bottom":c.yOffset=a.offset;break;case"left":c.xOffset=-a.offset;break}return{configurableVisibility:!1,data:{values:[{}]},mark:{type:"text",tooltip:null,clip:!1,...i,...c,text:a.text,align:a.align??q_[a.anchor],angle:a.angle,baseline:a.baseline,dx:a.dx,dy:a.dy,color:a.color,font:a.font,size:a.fontSize,fontStyle:a.fontStyle,fontWeight:a.fontWeight}}}class l2 extends en{constructor(n,r){const o={scrollbarSize:8,scrollbarPadding:2};super({data:{values:[{}]},mark:{type:"rect",fill:"#b0b0b0",fillOpacity:.6,stroke:"white",strokeWidth:1,strokeOpacity:1,cornerRadius:5,clip:!1},configurableVisibility:!1},n.layoutParent.context,n.layoutParent,n.view,"scrollbar-"+r,{blockEncodingInheritance:!0});he(this,ls);he(this,fc,Sn.ZERO);he(this,Wr,0);he(this,Ui,0);Gt(this,"viewportOffset",0);this.config=o,Ae(this,ls,r),this.interpolateViewportOffset=pd(this.context.animator,i=>{this.viewportOffset=i.x},50,.4,{x:this.viewportOffset}),this.addInteractionEventListener("mousedown",(i,s)=>{if(s.stopPropagation(),j(this,Wr)<=0)return;const a=d=>r=="vertical"?d.clientY:d.clientX;s.mouseEvent.preventDefault();const c=this.scrollOffset,l=a(s.mouseEvent),u=d=>{const h=lo(a(d)-l+c,0,j(this,Wr));this.interpolateViewportOffset({x:h/j(this,Wr)*j(this,Ui)})},f=()=>{document.removeEventListener("mousemove",u),document.removeEventListener("mouseup",f)};document.addEventListener("mouseup",f,!1),document.addEventListener("mousemove",u,!1)})}get scrollOffset(){return this.viewportOffset/j(this,Ui)*j(this,Wr)}render(n,r,o){super.render(n,j(this,fc),o)}updateScrollbar(n,r){const o=this.config.scrollbarPadding,i=this.config.scrollbarSize,s=j(this,ls)=="horizontal"?"width":"height",a=Math.min(1,n[s]/r[s]),c=n[s]-2*o,l=a*c;Ae(this,Wr,c-l),Ae(this,Ui,r[s]-n[s]),this.viewportOffset=lo(this.viewportOffset,0,j(this,Ui)),Ae(this,fc,j(this,ls)=="vertical"?new Sn(()=>n.x+n.width-i-o,()=>n.y+o+this.scrollOffset,()=>i,()=>l):new Sn(()=>n.x+o+this.scrollOffset,()=>n.y+n.height-i-o,()=>l,()=>i))}}ls=new WeakMap,fc=new WeakMap,Wr=new WeakMap,Ui=new WeakMap;class Y_ extends Eo{constructor(e,n,r={}){const o=n(),i=Object.keys(o.intervals);if(gi.every(l=>!i.includes(l)))throw new Error("SelectionRect requires at least one of the channels 'x' or 'y' to be present in the selection.");const s={name:"selectionRect",configurableVisibility:!1,resolve:{scale:{x:"forced",y:"forced"}},data:{values:u2(n())},encoding:{},layer:[]};i.includes("x")&&(s.encoding.x={field:"_x",type:null,title:null},s.encoding.x2={field:"_x2"}),i.includes("y")&&(s.encoding.y={field:"_y",type:null,title:null},s.encoding.y2={field:"_y2"}),s.layer.push({name:"selectionRectRect",mark:{type:"rect",clip:!0,fill:"#808080",fillOpacity:.05,stroke:"black",strokeWidth:1,strokeOpacity:.2,...r}});const a=l=>{const u=e.view.getScaleResolution(l);return`format(datum._${l}2 - datum._${l}, '.3s')`+(u.type==="locus"?" + 'b'":"")},c=r.measure=="inside"?9:r.measure=="outside"?-9:0;i.includes("x")&&c!=0&&s.layer.push({name:"selectionRectTextX",mark:{type:"text",align:"center",paddingX:5,dy:c,tooltip:null},encoding:{text:{expr:a("x")},y:i.includes("y")?{field:"_y2",type:null,title:null}:{value:1},y2:null}}),i.includes("y")&&c!=0&&s.layer.push({name:"selectionRectTextY",mark:{type:"text",align:"center",paddingY:5,dy:c,tooltip:null,angle:-90},encoding:{text:{expr:a("y")},x2:null}}),super(s,e.layoutParent.context,e.layoutParent,e.view,"selectionRect",{blockEncodingInheritance:!0,contributesToScaleDomain:!1}),n.addListener(()=>{const l=n();this.context.dataFlow.findDataSourceByKey(this).updateDynamicData(u2(l))})}}function u2(t){const e=t.intervals.x,n=t.intervals.y;return!e&&!n?[]:[{_x:e==null?void 0:e[0],_x2:e==null?void 0:e[1],_y:n==null?void 0:n[0],_y2:n==null?void 0:n[1]}]}class f2{constructor(e,n,r){he(this,Tu);if(this.layoutParent=n,this.view=e,this.serial=r,this.background=void 0,this.backgroundStroke=void 0,this.axes={},this.gridLines={},this.scrollbars={},this.selectionRect=void 0,this.title=void 0,this.coords=Sn.ZERO,e.needsAxes.x||e.needsAxes.y){const o=e.spec,i="view"in o?o==null?void 0:o.view:void 0,s=Q_(i);s&&(this.background=new en(s,n.context,n,e,"background"+r,{blockEncodingInheritance:!0}));const a=Z_(i);a&&(this.backgroundStroke=new en(a,n.context,n,e,"backgroundStroke"+r,{blockEncodingInheritance:!0}));const c=W_(e.spec.title);if(c){const l=new en(c,n.context,n,e,"title"+r,{blockEncodingInheritance:!0});this.title=l}}e.spec.viewportWidth!=null&&(this.scrollbars.horizontal=new l2(this,"horizontal")),e.spec.viewportHeight!=null&&(this.scrollbars.vertical=new l2(this,"vertical")),pe(this,Tu,Zv).call(this)}*getChildren(){this.background&&(yield this.background),this.backgroundStroke&&(yield this.backgroundStroke),this.title&&(yield this.title),yield*Object.values(this.axes),yield*Object.values(this.gridLines),yield this.view,yield*Object.values(this.scrollbars),this.selectionRect&&(yield this.selectionRect)}async createAxes(){const{view:e,axes:n,gridLines:r}=this,o=(a,c)=>{const l=a.getAxisProps();if(l===null)return;const u=l?{...l}:{};if(!u.orient){for(const f of Yl[c])if(!n[f]){u.orient=f;break}if(!u.orient)throw new Error("No slots available for an axis! Perhaps a LayerView has more than two children?")}if(u.title??(u.title=a.getTitle()),!Yl[c].includes(u.orient))throw new Error(`Invalid axis orientation "${u.orient}" on channel "${c}"!`);return u},i=async(a,c,l)=>{const u=o(a,c);if(u){if(n[u.orient])throw new Error(`An axis with the orient "${u.orient}" already exists!`);const f=new n2(u,a.scaleResolution.type,this.layoutParent.context,this.layoutParent,l);n[u.orient]=f,await f.initializeChildren()}},s=async(a,c,l)=>{const u=o(a,c);if(u&&(u.grid||u.chromGrid)){const f=new L_(u,a.scaleResolution.type,this.layoutParent.context,this.layoutParent,l);r[u.orient]=f,await f.initializeChildren()}};for(const a of["x","y"])if(e.needsAxes[a]){const c=e.resolutions.axis[a];if(!c)continue;await i(c,a,e)}for(const a of["x","y"])if(e.needsAxes[a]&&e.getConfiguredOrDefaultResolution(a,"axis")!="excluded"){const c=e.getAxisResolution(a);if(!c)continue;await s(c,a,e)}if(e instanceof Eo){for(const a of e)for(const[c,l]of Object.entries(a.resolutions.axis)){const u=l.getAxisProps();u&&u.orient&&await i(l,c,a)}for(const a of e)for(const[c,l]of Object.entries(a.resolutions.axis)){const u=l.getAxisProps();u&&!u.orient&&await i(l,c,a)}}[...Object.values(n),...Object.values(r)].forEach(a=>a.visit(c=>{c instanceof en&&c.resolve("scale")}))}getOverhang(){const e=n=>{const r=this.axes[n];return r?Math.max(r.getPerpendicularSize()+(r.axisProps.offset??0),0):0};return new Nt(e("top"),e("right"),e("bottom"),e("left")).add(this.view.getOverhang())}getOverhangAndPadding(){return this.getOverhang().add(this.view.getPadding())}}Tu=new WeakSet,Zv=function(){const e=this.view,n=r=>{this.view.context.glHelper.canvas.style.cursor=r};for(const[r,o]of e.paramMediator.paramConfigs){if(!("select"in o))continue;const i=yl(o.select);if(!f1(i))continue;const s=i.encodings,a=Object.fromEntries(s.map(S=>{const E=this.view.getScaleResolution(S),I=E==null?void 0:E.scale;if(!I||!St(I.type))throw new Error(`No continuous scale found for interval selection param "${r}" on channel "${S}"! Scale type is "${(I==null?void 0:I.type)??"none"}".`);return[S,E]}));if(this.selectionRect)throw new Error("Only one interval selection per container is currently allowed!");let c=!1,l=!1,u=!1,f=null;const d=(S,E)=>Object.fromEntries(s.map(I=>[I,[Math.min(S[I],E[I]),Math.max(S[I],E[I])]])),h=e.paramMediator.createExpression(r),p=e.paramMediator.getSetter(r);o.value&&p({type:"interval",intervals:o.value});const y=()=>{p(c1(s)),n(null)};this.selectionRect=new Y_(this,h,i.mark),this.selectionRect.initializeChildren();const v=S=>{const E={x:0,y:0},I=e.coords.normalizePoint(S.x,S.y,!0);for(const _ of s){const B=a[_].scale,N=B.invert(_=="x"?I.x:I.y);E[_]=N+(["index","locus"].includes(B.type)?.5:0)}return E},b=S=>{var N,F,M,C;const{intervals:E}=S,I=(Y,Q,oe)=>{const se=(ye,de)=>de==null?null:a[ye].scale(de),ae=se("x",Y)??oe,ce=se("y",Q)??oe;return e.coords.denormalizePoint(ae,ce,!0)},_=I((N=E.x)==null?void 0:N[0],(F=E.y)==null?void 0:F[0],0),B=I((M=E.x)==null?void 0:M[1],(C=E.y)==null?void 0:C[1],1);return Sn.create(_.x,_.y,B.x-_.x,B.y-_.y)};e.addInteractionEventListener("mousedown",(S,E)=>{if(E.mouseEvent.button!=0)return;if(f=c?b(h()):null,f)n("grabbing"),l=!0;else{const F=E.point;if(h1(h())&&(l=!0),E.mouseEvent.shiftKey)y(),u=!0;else if(h1(h())){const C=(Y,Q)=>{e.removeInteractionEventListener("mouseup",C);const oe=Q.point;F.subtract(oe).length<2&&y()};e.addInteractionEventListener("mouseup",C);return}else return}E.stopPropagation();const I=E.point,_=Xt.fromMouseEvent(E.mouseEvent).subtract(I),B=F=>{const M=Xt.fromMouseEvent(F).subtract(_);let C;if(f){const Y=M.subtract(I),Q=f.translate(Y.x,Y.y);C=d(v(new Xt(Q.x,Q.y)),v(new Xt(Q.x2,Q.y2)))}else C=d(v(I),v(M));for(const Y of s){const Q=a[Y],{zoomExtent:oe,scale:se}=Q,ae=C[Y];if(["index","locus"].includes(se.type)&&(ae[0]=Math.ceil(ae[0]),ae[1]=Math.ceil(ae[1])),f){const ce=ae[1]-ae[0],ye=oe[0],de=oe[1];ae[0]<ye&&(ae[0]=ye,ae[1]=ye+ce),ae[1]>de&&(ae[1]=de,ae[0]=de-ce)}else ae[0]=Math.max(oe[0],ae[0]),ae[1]=Math.min(oe[1],ae[1]);ae[1]=Math.min(oe[1],ae[1])}p({type:"interval",intervals:C})},N=()=>{document.removeEventListener("mousemove",B),document.removeEventListener("mouseup",N),u=!1,f&&(n("move"),f=null)};document.addEventListener("mousemove",B),document.addEventListener("mouseup",N)}),e.addInteractionEventListener("click",(S,E)=>{E.mouseEvent.button==0&&l&&(E.stopPropagation(),l=!1)},!0);const A=S=>N5(h(),v(S));e.addInteractionEventListener("dblclick",(S,E)=>{A(E.point)&&(y(),E.stopPropagation())},!0),e.addInteractionEventListener("mousemove",(S,E)=>{A(E.point)?u||(c=!0,f||n("move")):(c=!1,f||n(null))})}};function Q_(t){if(t!=null&&t.fill||t!=null&&t.fillOpacity||t!=null&&t.shadowOpacity)return{configurableVisibility:!1,data:{values:[{}]},mark:{color:t.fill,opacity:t.fillOpacity??(t.fill?1:0),type:"rect",clip:!1,tooltip:null,minHeight:1,minOpacity:0,shadowBlur:t.shadowBlur,shadowColor:t.shadowColor,shadowOffsetX:t.shadowOffsetX,shadowOffsetY:t.shadowOffsetY,shadowOpacity:t.shadowOpacity}}}function Z_(t){if(!(!t||!t.stroke||t.strokeWidth===0||t.strokeOpacity===0))return{configurableVisibility:!1,resolve:{scale:{x:"excluded",y:"excluded"},axis:{x:"excluded",y:"excluded"}},data:{values:[{x:0,y:0,x2:1,y2:0},{x:1,y:0,x2:1,y2:1},{x:1,y:1,x2:0,y2:1},{x:0,y:1,x2:0,y2:0}]},mark:{size:t.strokeWidth??1,color:t.stroke??"lightgray",strokeCap:"square",opacity:t.strokeOpacity??1,type:"rule",clip:!1,tooltip:null},encoding:{x:{field:"x",type:"quantitative",scale:null},y:{field:"y",type:"quantitative",scale:null},x2:{field:"x2"},y2:{field:"y2"}}}}class X_ extends Da{constructor(n,r,o,i,s,a,c){super(n,r,o,i,s,c);he(this,He);he(this,us,1/0);he(this,fs,10);he(this,nn,[]);he(this,Gi,{});he(this,hs,0);this.spec=n,Ae(this,fs,n.spacing??10),Ae(this,us,a),Ae(this,nn,[]),this.wrappingFacet=!1}appendChild(n){n.layoutParent??(n.layoutParent=this),j(this,nn).push(new f2(n,this,j(this,hs))),Ov(this,hs)._++}setChildren(n){Ae(this,nn,[]);for(const r of n)this.appendChild(r)}replaceChild(n,r){const o=j(this,nn).findIndex(i=>i.view==n);if(o>=0)j(this,nn)[o]=new f2(r,this,j(this,hs));else throw new Error("Not my child view!")}get children(){return j(this,nn).map(n=>n.view)}get childCount(){return j(this,nn).length}async createAxes(){const n=[];for(const r of gi){const o=this.resolutions.axis[r];if(o){const i=o.getAxisProps();if(i){const s={title:o.getTitle(),orient:Yl[r][0],...i},a=new n2(s,o.scaleResolution.type,this.context,this,this);n.push(a.initializeChildren()),j(this,Gi)[r]=a}}}return Promise.all([...n,...j(this,nn).map(r=>r.createAxes())])}*[Symbol.iterator](){for(const n of j(this,nn))yield*n.getChildren();for(const n of Object.values(j(this,Gi)))yield n}getOverhang(){return pe(this,He,Kv).call(this).union(pe(this,He,ku).call(this))}getSize(){return this._cache("size",()=>new Lr(pe(this,He,$0).call(this,"column"),pe(this,He,$0).call(this,"row")).addPadding(pe(this,He,ku).call(this)))}render(n,r,o={}){if(super.render(n,r,o),!this.isConfiguredVisible())return;this.layoutParent||(r=r.shrink(this.getPadding())),r=r.shrink(pe(this,He,ku).call(this)),n.pushView(this,r);const i={devicePixelRatio:n.getDevicePixelRatio()},s=Bb(pe(this,He,J0).call(this,"column"),r.width,i),a=Bb(pe(this,He,J0).call(this,"row"),r.height,i),c=new t2(j(this,He,Vi).length,j(this,us)??1/0),l=u=>Math.round(u*devicePixelRatio)/devicePixelRatio;for(const[u,f]of j(this,He,Vi).entries()){const{view:d,axes:h,gridLines:p,background:y,backgroundStroke:v,title:b,selectionRect:A}=f,[S,E]=c.getCellCoords(u),I=s[pe(this,He,ep).call(this,"column",S)],_=a[pe(this,He,ep).call(this,"row",E)],B=d.getViewportSize(),N=d.getSize(),F=d.getOverhang(),M=I.location-F.left,C=_.location-F.top,Y=(q,W)=>(q[W].grow?(W=="width"?I:_).size:q[W].px)+F[W],Q=Y(B,"width"),oe=Y(B,"height"),se=Y(N,"width"),ae=Y(N,"height"),ce=f.scrollbars.horizontal,ye=f.scrollbars.vertical,de=ce?()=>l(ce.viewportOffset):()=>0,Ce=ye?()=>l(ye.viewportOffset):()=>0,me=new Sn(()=>r.x+M,()=>r.y+C,()=>Q,()=>oe),Ee=d.isScrollable(),De=Ee?new Sn(()=>r.x+M-de(),()=>r.y+C-Ce(),()=>se,()=>ae):me;f.coords=me;const Ge=o.clipRect?me.intersect(o.clipRect):me;y==null||y.render(n,Ge,{...o,clipRect:void 0});for(const q of Object.values(p))q.render(n,me,o);const Ve=J_(d)||Ee;Ve&&d.render(n,De,{...o,clipRect:Ge}),v==null||v.render(n,Ge,{...o,clipRect:void 0});for(const[q,W]of Object.entries(h)){const ee=q=="left"||q=="right"?"vertical":"horizontal",J=f.scrollbars[ee],fe=J?me.modify(ee=="vertical"?{y:()=>De.y,height:ae}:{x:()=>De.x,width:se}):me,L=h2(fe,q,W);let D=o.clipRect;J&&(D=L.intersect(D).intersect(J?me.modify(ee=="vertical"?{x:-1e5,width:2e5}:{y:-1e5,height:2e5}):void 0)),W.render(n,L,{...o,clipRect:D})}for(const q of Object.values(j(this,Gi))){const ee=q.axisProps.orient;(ee=="left"&&S==0||ee=="right"&&S==c.nCols-1||ee=="top"&&E==0||ee=="bottom"&&E==c.nRows-1)&&q.render(n,h2(me.shrink(f.view.getOverhang()),ee,q),o)}Ve||d.render(n,De,o),A==null||A.render(n,De,o);for(const q of Object.values(f.scrollbars))q.updateScrollbar(me,De),q.render(n,r,o);b==null||b.render(n,me,o)}n.popView(this)}propagateInteractionEvent(n){if(this.handleInteractionEvent(void 0,n,!0),n.stopped)return;const r=j(this,He,Vi).find(i=>i.coords.containsPoint(n.point.x,n.point.y));for(const i of Object.values((r==null?void 0:r.scrollbars)??{}))if(i.coords.containsPoint(n.point.x,n.point.y)&&(i.propagateInteractionEvent(n),n.stopped))return;const o=r==null?void 0:r.view;if(o){if(o.propagateInteractionEvent(n),n.stopped)return;(o instanceof en||o instanceof Eo)&&M_(n,r.coords,i=>pe(this,He,Jv).call(this,r.coords,r.view,i),this.context.getCurrentHover(),this.context.animator)}n.stopped||this.handleInteractionEvent(void 0,n,!1)}getDefaultResolution(n,r){return"independent"}}us=new WeakMap,fs=new WeakMap,nn=new WeakMap,Gi=new WeakMap,hs=new WeakMap,He=new WeakSet,Vi=function(){return j(this,nn).filter(n=>n.view.isConfiguredVisible())},Xv=function(){return new t2(j(this,He,Vi).length,j(this,us)??1/0)},gc=function(n){const r=n=="column"?"width":"height",o=(i,s)=>i.map(a=>{const l=j(this,He,Vi)[a].getOverhangAndPadding();return n=="column"?s?l.right:l.left:s?l.bottom:l.top}).reduce((a,c)=>Math.max(a,c),0);return 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a=i*t+o;a<this.n&&s.push(a)}}return e}get colIndices(){const e=[],t=this.nCols,r=this.nRows;for(let i=0;i<t;i++){const s=[];e.push(s);for(let o=0;o<r;o++){const a=o*t+i;a<this.n&&s.push(a)}}return e}getCellIndex(e,t){let r=0;if(this.maxCols==1/0)r=t==0?e:void 0;else{if(e>=this.maxCols)return;r=t*this.nCols+e}return r<this.n?r:void 0}getCellCoords(e){if(!(e<0||e>=this.n))return[e%this.nCols,Math.floor(e/this.nCols)]}}const hT="chromosome_ticks_and_labels",dT={x:"width",y:"height"};function bh(n){return n=="x"?"y":"x"}const ou={x:["bottom","top"],y:["left","right"]},xh=Object.fromEntries(Object.entries(ou).map(([n,e])=>e.map(t=>[t,n])).flat(1));function qn(n){return xh[n]}class ky extends Ri{constructor(e,t,r,i,s,o){const a=t=="locus",c={...a?mT:Fy,...pT(t,e),...e};super(a?gT(c,t):Py(c,t),r,i,s,`axis_${e.orient}`,{blockEncodingInheritance:!0,contributesToScaleDomain:!1,...o}),this.axisProps=c}getSize(){const e={px:this.getPerpendicularSize()},t={grow:1};return xh[this.axisProps.orient]=="x"?new Wn(t,e):new Wn(e,t)}getPerpendicularSize(){return Ah(this.axisProps)}isPickingSupported(){return!1}}function Ah(n){const e=qn(n.orient);let t=n.ticks&&n.tickSize||0;return n.labels&&(t+=n.labelPadding,e=="x"?t+=n.labelFontSize:t+=30),n.title&&(t+=n.titlePadding+n.titleFontSize),t=Math.min(n.maxExtent||1/0,Math.max(n.minExtent||0,t)),t}const Fy={values:null,minExtent:20,maxExtent:1/0,offset:0,domain:!0,domainWidth:1,domainColor:"gray",domainDash:null,domainDashOffset:0,domainCap:"square",ticks:!0,tickSize:5,tickWidth:1,tickColor:"gray",tickDash:null,tickDashOffset:0,tickCap:"square",tickCount:null,tickMinStep:null,labels:!0,labelAlign:"center",labelBaseline:"middle",labelPadding:4,labelFontSize:10,labelLimit:180,labelColor:"black",format:null,titleColor:"black",titleFont:"sans-serif",titleFontSize:10,titlePadding:3};function pT(n,e){const t=e.orient,r=n=="nominal"||n=="ordinal";let i="center",s="middle",o=e.labelAngle??((t=="top"||t=="bottom")&&r?-90:0);switch(t){case"left":i="right";break;case"right":i="left";break;case"top":case"bottom":Math.abs(o)>30?(i=o>0==(t=="bottom")?"left":"right",s="middle"):s=t=="top"?"alphabetic":"top";break}return{labelAlign:i,labelAngle:o,labelBaseline:s}}function Py(n,e){const t={...n,extent:Ah(n)},r=qn(t.orient),i=bh(r),s=t.orient=="bottom"||t.orient=="right"?1:-1,o=t.orient=="bottom"||t.orient=="left"?1:0,a=()=>({name:"domain",data:{values:[{}]},mark:{type:"rule",clip:!1,strokeDash:t.domainDash,strokeCap:t.domainCap,color:t.domainColor,[i]:o,size:t.domainWidth}}),c=()=>({name:"labels",mark:{type:"text",clip:!1,align:t.labelAlign,angle:t.labelAngle,baseline:t.labelBaseline,[i+"Offset"]:(t.tickSize+t.labelPadding)*s,[i]:o,size:t.labelFontSize,color:t.labelColor,minBufferSize:1500},encoding:{[r]:{field:"value",type:e},text:{field:"label"}}}),u=()=>({name:"ticks",mark:{type:"rule",clip:!1,strokeDash:t.tickDash,strokeCap:t.tickCap,color:t.tickColor,size:t.tickWidth,minBufferSize:300},encoding:{[i]:{value:o},[i+"2"]:{value:o-t.tickSize/t.extent*(o?1:-1)}}}),l=()=>({name:"title",data:{values:[{}]},mark:{type:"text",clip:!1,align:"center",baseline:t.orient=="bottom"?"bottom":"top",angle:[0,90,0,-90][["top","right","bottom","left"].indexOf(t.orient)],text:t.title,color:t.titleColor,[r]:.5,[i]:1-o}}),f=()=>{const h={name:"ticks_and_labels",encoding:{[r]:{field:"value",type:e}},layer:[]};return t.ticks&&h.layer.push(u()),t.labels&&h.layer.push(c()),h},d={resolve:{scale:{[r]:"forced"}},[dT[bh(r)]]:t.extent,data:{lazy:{type:"axisTicks",channel:r,axis:n}},layer:[]};return t.domain&&d.layer.push(a()),(t.ticks||t.labels)&&d.layer.push(f()),t.title&&d.layer.push(l()),d}const mT={...Fy,chromTicks:!0,chromTickSize:18,chromTickWidth:1,chromTickColor:"#989898",chromTickDash:[4,2],chromTickDashOffset:1,chromLabels:!0,chromLabelFontSize:13,chromLabelFontWeight:"normal",chromLabelFontStyle:"normal",chromLabelColor:"black",chromLabelAlign:"left",chromLabelPadding:7};function gT(n,e){const t={...n,extent:Ah(n)},r=qn(t.orient),i=bh(r),s=t.orient=="bottom"||t.orient=="left"?1:0,o=()=>({name:"chromosome_ticks",mark:{type:"rule",strokeDash:n.chromTickDash,strokeDashOffset:n.chromTickDashOffset,[i]:s,[i+"2"]:s-t.chromTickSize/t.extent*(s?1:-1),color:n.chromTickColor,size:t.chromTickWidth}}),a=()=>{let l;switch(t.orient){case"top":l={y:0,angle:0,paddingX:4,dy:-t.chromLabelPadding,viewportEdgeFadeWidthLeft:20,viewportEdgeFadeWidthRight:20,viewportEdgeFadeDistanceRight:-10,viewportEdgeFadeDistanceLeft:-20};break;case"bottom":l={y:1,angle:0,paddingX:4,dy:t.chromLabelPadding+t.chromLabelFontSize*.73,viewportEdgeFadeWidthLeft:20,viewportEdgeFadeWidthRight:20,viewportEdgeFadeDistanceRight:-10,viewportEdgeFadeDistanceLeft:-20};break;case"left":l={x:1,angle:-90,paddingY:4,dy:-t.chromLabelPadding,viewportEdgeFadeWidthBottom:20,viewportEdgeFadeWidthTop:20,viewportEdgeFadeDistanceBottom:-20,viewportEdgeFadeDistanceTop:-10};break;case"right":l={x:0,angle:90,align:"right",paddingY:4,dy:-t.chromLabelPadding};break;default:l={}}return{name:"chromosome_labels",mark:{type:"text",size:t.chromLabelFontSize,font:t.chromLabelFont,fontWeight:t.chromLabelFontWeight,fontStyle:t.chromLabelFontStyle,color:t.chromLabelColor,align:n.chromLabelAlign,baseline:"alphabetic",clip:!1,...l},encoding:{[r+"2"]:{field:"continuousEnd",type:e},text:{field:"name"}}}};let c;switch(t.orient){case"bottom":case"top":c={};break;case"left":c={labelAngle:-90,labelAlign:"center",labelPadding:6};break;case"right":c={labelAngle:90,labelAlign:"center",labelPadding:6};break;default:c={}}const u=Py({...n,...c},e);if(n.chromTicks||n.chromLabels){const l={name:hT,data:{lazy:{type:"axisGenome",channel:qn(t.orient)}},encoding:{[r]:{field:"continuousStart",type:e,band:0}},layer:[]};if(n.chromTicks&&l.layer.push(o()),n.chromLabels){l.layer.push(a());let f;u.layer.filter(d=>d.name=="ticks_and_labels").forEach(d=>d.layer.filter(h=>h.name=="labels").forEach(h=>{f=h.mark})),f&&(t.orient=="top"||t.orient=="bottom"?(f.viewportEdgeFadeWidthLeft=30,f.viewportEdgeFadeDistanceLeft=40):(f.viewportEdgeFadeWidthBottom=30,f.viewportEdgeFadeDistanceBottom=40))}u.layer.push(l)}return u}class yT{constructor(e){R(this,Jr);R(this,er,0);R(this,tr,0);G(this,Jr,new Array(e))}push(e){E(this,Jr)[E(this,er)]=e,G(this,er,(E(this,er)+1)%this.size),G(this,tr,Math.min(E(this,tr)+1,this.size))}get(){const e=E(this,Jr);return E(this,tr)<this.size?e.slice(0,E(this,tr)):e.slice(E(this,er),this.size).concat(e.slice(0,E(this,er)))}get size(){return E(this,Jr).length}get length(){return E(this,tr)}}Jr=new WeakMap,er=new WeakMap,tr=new WeakMap;let Lr,My=0;function Ry(){return performance.now()-My<50}function bT(n){return function(...e){My=performance.now(),n(...e)}}function xT(n,e,t,r,i){if(t=bT(t),n.type=="wheel"){n.uiEvent.preventDefault();const s=n.uiEvent,o=s.deltaMode?120:1;if(!s.deltaX&&!s.deltaY)return;Lr==null||Lr.stop();let{x:a,y:c}=n.point;if(r){const u=r.mark.encoders;u.x&&!u.x2&&!u.x.constant&&(a=+u.x(r.datum)*e.width+e.x),u.y&&!u.y2&&!u.y.constant&&(c=(1-+u.y(r.datum))*e.height+e.y)}Math.abs(s.deltaX)<Math.abs(s.deltaY)?t({x:a,y:c,xDelta:0,yDelta:0,zDelta:s.deltaY*o/300}):t({x:a,y:c,xDelta:-s.deltaX*o,yDelta:0,zDelta:0})}else if(n.type=="mousedown"&&n.mouseEvent.button===0){Lr&&Lr.stop();const s=new yT(30),o=n.mouseEvent;o.preventDefault();let a=at.fromMouseEvent(o);const c=f=>{const d=at.fromMouseEvent(f);s.push({point:d,timestamp:performance.now()});const h=d.subtract(a);t({x:a.x,y:a.y,xDelta:h.x,yDelta:h.y,zDelta:0}),a=d},u=()=>{const d=performance.now(),h=s.get().filter(A=>d-A.timestamp<160);if(h.length<5||!i||AT(h))return;const p=h.at(-1),m=h[0],g=p.point.subtract(m.point).multiply(1/(p.timestamp-m.timestamp));let y=a.x,x=a.y;Lr=yh(i,A=>{t({x:A.x,y:A.y,xDelta:y-A.x,yDelta:x-A.y,zDelta:0}),y=A.x,x=A.y},150,.5,{x:y,y:x}),Lr({x:a.x-g.x*250,y:a.y-g.y*250})},l=()=>{document.removeEventListener("mousemove",c),document.removeEventListener("mouseup",l),u()};document.addEventListener("mouseup",l,!1),document.addEventListener("mousemove",c,!1)}}function AT(n){const e=n[Math.floor(n.length/2)],t=e.point.subtract(n[0].point).multiply(e.timestamp-n[0].timestamp),r=n.at(-1).point.subtract(e.point).multiply(n.at(-1).timestamp-e.timestamp),i=t.length;return r.length/i<.4}class wT extends Ri{constructor(e,t,r,i,s,o){const c={...t=="locus"?vT:Oy,...e};super(DT(c,t),r,i,s,`axisGrid_${e.orient}`,{blockEncodingInheritance:!0,contributesToScaleDomain:!1,...o}),this.axisProps=c}getOrient(){return this.axisProps.orient}isPickingSupported(){return!1}}const Oy={values:null,grid:!1,gridCap:"butt",gridColor:"lightgray",gridDash:null,gridOpacity:1,gridWidth:1,tickCount:null,tickMinStep:null},vT={...Oy,chromGrid:!1,chromGridCap:"butt",chromGridColor:"gray",chromGridDash:[1,5],chromGridOpacity:1,chromGridWidth:1};function ST(n,e){const t=n,r=qn(t.orient);return{name:"grid_lines",data:{lazy:{type:"axisTicks",channel:r,axis:n}},mark:{type:"rule",strokeDash:t.gridDash,strokeCap:t.gridCap,color:t.gridColor,size:t.gridWidth,opacity:t.gridOpacity,minBufferSize:300},encoding:{[r]:{field:"value",type:e}}}}function ET(n,e){const t=n,r=qn(t.orient);return{name:"chromosome_lines",data:{lazy:{type:"axisGenome",channel:r}},mark:{type:"rule",strokeDash:t.chromGridDash,strokeCap:t.chromGridCap,color:t.chromGridColor,size:t.chromGridWidth,opacity:t.chromGridOpacity},encoding:{[r]:{field:"continuousStart",type:e,band:0}}}}function CT(n,e){const t=n,r=qn(t.orient);return{name:"chromosome_fill",data:{lazy:{type:"axisGenome",channel:r}},mark:{type:"rect"},encoding:{[r]:{field:"continuousStart",type:e,band:0},[r+"2"]:{field:"continuousEnd",band:0},fill:{field:"odd",type:"nominal",scale:{domain:[!1,!0],range:[t.chromGridFillEven??"white",t.chromGridFillOdd??"white"]}},opacity:{field:"odd",type:"nominal",scale:{type:"ordinal",domain:[!1,!0],range:[t.chromGridFillEven?1:0,t.chromGridFillOdd?1:0]}}}}}function DT(n,e){const t={...n},r=[];return t.chromGrid&&(t.chromGridFillOdd||t.chromGridFillEven)&&r.push(CT(t,e)),t.chromGrid&&t.chromGridOpacity>0&&r.push(ET(t,e)),t.grid&&t.gridOpacity>0&&r.push(ST(t,e)),{name:"grid_layers",configurableVisibility:!1,resolve:{scale:{[qn(n.orient)]:"forced",fill:"independent",opacity:"independent"}},layer:r}}const Ny={anchor:"middle",frame:"group",offset:10,orient:"top",align:void 0,angle:0,baseline:"alphabetic",dx:0,dy:0,color:void 0,font:void 0,fontSize:12,fontStyle:"normal",fontWeight:"normal"},IT={orient:"left",anchor:"middle",align:"right",baseline:"middle",angle:0,fontSize:12},TT={orient:"top",anchor:"start",align:"left",baseline:"top",offset:-10,dx:10,fontSize:12},BT={start:0,middle:.5,end:1},kT={start:"left",middle:"center",end:"right"};function FT(n){if(!n)return;const e=me(n)?{text:n}:n;if(!e.text||e.orient=="none")return;const t={"track-title":IT,overlay:TT}[e.style]??{},r={...Ny,...t,...e};let i={},s={x:0,y:0};const o=BT[r.anchor??"middle"];switch(r.orient){case"top":s={x:o,y:1},i={baseline:"alphabetic",angle:0};break;case"right":s={x:1,y:1-o},i={baseline:"alphabetic",angle:90};break;case"bottom":s={x:o,y:0},i={baseline:"top",angle:0};break;case"left":s={x:0,y:o},i={baseline:"alphabetic",angle:-90};break}const a={...Ny,...i,...t,...e},c={xOffset:0,yOffset:0};switch(r.orient){case"top":c.yOffset=-a.offset;break;case"right":c.xOffset=a.offset;break;case"bottom":c.yOffset=a.offset;break;case"left":c.xOffset=-a.offset;break}return{configurableVisibility:!1,data:{values:[{}]},mark:{type:"text",tooltip:null,clip:!1,...s,...c,text:a.text,align:a.align??kT[a.anchor],angle:a.angle,baseline:a.baseline,dx:a.dx,dy:a.dy,color:a.color,font:a.font,size:a.fontSize,fontStyle:a.fontStyle,fontWeight:a.fontWeight}}}class Ly extends ft{constructor(t,r){const i={scrollbarSize:8,scrollbarPadding:2};super({data:{values:[{}]},mark:{type:"rect",fill:"#b0b0b0",fillOpacity:.6,stroke:"white",strokeWidth:1,strokeOpacity:1,cornerRadius:5,clip:!1},configurableVisibility:!1},t.layoutParent.context,t.layoutParent,t.view,"scrollbar-"+r,{blockEncodingInheritance:!0});R(this,ws);R(this,Sa,Ft.ZERO);R(this,nr,0);R(this,$r,0);Y(this,"viewportOffset",0);this.config=i,G(this,ws,r),this.interpolateViewportOffset=yh(this.context.animator,s=>{this.viewportOffset=s.x},50,.4,{x:this.viewportOffset}),this.addInteractionEventListener("mousedown",(s,o)=>{if(o.stopPropagation(),E(this,nr)<=0)return;const a=d=>r=="vertical"?d.clientY:d.clientX;o.mouseEvent.preventDefault();const c=this.scrollOffset,u=a(o.mouseEvent),l=d=>{const h=vi(a(d)-u+c,0,E(this,nr));this.interpolateViewportOffset({x:h/E(this,nr)*E(this,$r)})},f=()=>{document.removeEventListener("mousemove",l),document.removeEventListener("mouseup",f)};document.addEventListener("mouseup",f,!1),document.addEventListener("mousemove",l,!1)})}get scrollOffset(){return this.viewportOffset/E(this,$r)*E(this,nr)}render(t,r,i){super.render(t,E(this,Sa),i)}updateScrollbar(t,r){const i=this.config.scrollbarPadding,s=this.config.scrollbarSize,o=E(this,ws)=="horizontal"?"width":"height",a=Math.min(1,t[o]/r[o]),c=t[o]-2*i,u=a*c;G(this,nr,c-u),G(this,$r,r[o]-t[o]),this.viewportOffset=vi(this.viewportOffset,0,E(this,$r)),G(this,Sa,E(this,ws)=="vertical"?new Ft(()=>t.x+t.width-s-i,()=>t.y+i+this.scrollOffset,()=>s,()=>u):new Ft(()=>t.x+i+this.scrollOffset,()=>t.y+t.height-s-i,()=>u,()=>s))}}ws=new WeakMap,Sa=new WeakMap,nr=new WeakMap,$r=new WeakMap;class PT extends Ri{constructor(t,r,i={}){const s=r(),o=Object.keys(s.intervals);if(Dr.every(l=>!o.includes(l)))throw new Error("SelectionRect requires at least one of the channels 'x' or 'y' to be present in the selection.");const a={name:"selectionRect",configurableVisibility:!1,resolve:{scale:{x:"forced",y:"forced"}},data:{values:zy(r())},encoding:{},layer:[]};o.includes("x")&&(a.encoding.x={field:"_x",type:null,title:null},a.encoding.x2={field:"_x2"}),o.includes("y")&&(a.encoding.y={field:"_y",type:null,title:null},a.encoding.y2={field:"_y2"}),a.layer.push({name:"selectionRectRect",mark:{type:"rect",clip:!0,fill:"#808080",fillOpacity:.05,stroke:"black",strokeWidth:1,strokeOpacity:.2,...i}});const c=l=>{const f=t.view.getScaleResolution(l);return`format(datum._${l}2 - datum._${l}, '.3s')`+(f.type==="locus"?" + 'b'":"")},u=i.measure=="inside"?9:i.measure=="outside"?-9:0;o.includes("x")&&u!=0&&a.layer.push({name:"selectionRectTextX",mark:{type:"text",align:"center",paddingX:5,dy:u,tooltip:null},encoding:{text:{expr:c("x")},y:o.includes("y")?{field:"_y2",type:null,title:null}:{value:1},y2:null}}),o.includes("y")&&u!=0&&a.layer.push({name:"selectionRectTextY",mark:{type:"text",align:"center",paddingY:5,dy:u,tooltip:null,angle:-90},encoding:{text:{expr:c("y")},x2:null}});super(a,t.layoutParent.context,t.layoutParent,t.view,"selectionRect",{blockEncodingInheritance:!0,contributesToScaleDomain:!1});Y(this,"_selectionExpr");Y(this,"_selectionListener");this._selectionExpr=r,this._selectionListener=()=>{var d;const l=r(),f=(d=this.flowHandle)==null?void 0:d.dataSource;if(!f)throw new Error("Cannot find selection rect data source handle!");f.updateDynamicData(zy(l))},r.addListener(this._selectionListener)}dispose(){this._selectionExpr.removeListener(this._selectionListener),super.dispose()}}function zy(n){const e=n.intervals.x,t=n.intervals.y;return!e&&!t?[]:[{_x:e==null?void 0:e[0],_x2:e==null?void 0:e[1],_y:t==null?void 0:t[0],_y2:t==null?void 0:t[1]}]}class Uy{constructor(e,t,r){R(this,Iu);if(this.layoutParent=t,this.view=e,this.serial=r,this.background=void 0,this.backgroundStroke=void 0,this.axes={},this.gridLines={},this.scrollbars={},this.selectionRect=void 0,this.title=void 0,this.coords=Ft.ZERO,e.needsAxes.x||e.needsAxes.y){const i=e.spec,s="view"in i?i==null?void 0:i.view:void 0,o=MT(s);o&&(this.background=new ft(o,t.context,t,e,"background"+r,{blockEncodingInheritance:!0}));const a=RT(s);a&&(this.backgroundStroke=new ft(a,t.context,t,e,"backgroundStroke"+r,{blockEncodingInheritance:!0}));const c=FT(e.spec.title);if(c){const u=new ft(c,t.context,t,e,"title"+r,{blockEncodingInheritance:!0});this.title=u}}e.spec.viewportWidth!=null&&(this.scrollbars.horizontal=new Ly(this,"horizontal")),e.spec.viewportHeight!=null&&(this.scrollbars.vertical=new Ly(this,"vertical")),O(this,Iu,Bx).call(this)}*getChildren(){this.background&&(yield this.background),this.backgroundStroke&&(yield this.backgroundStroke),this.title&&(yield this.title),yield*Object.values(this.axes),yield*Object.values(this.gridLines),yield this.view,yield*Object.values(this.scrollbars),this.selectionRect&&(yield this.selectionRect)}async createAxes(){const{view:e,axes:t,gridLines:r}=this,i=(a,c)=>{const u=a.getAxisProps();if(u===null)return;const l=u?{...u}:{};if(!l.orient){for(const f of ou[c])if(!t[f]){l.orient=f;break}if(!l.orient)throw new Error("No slots available for an axis! Perhaps a LayerView has more than two children?")}if(l.title??(l.title=a.getTitle()),!ou[c].includes(l.orient))throw new Error(`Invalid axis orientation "${l.orient}" on channel "${c}"!`);return l},s=async(a,c,u)=>{const l=i(a,c);if(l){if(t[l.orient])throw new Error(`An axis with the orient "${l.orient}" already exists!`);const f=new ky(l,a.scaleResolution.type,this.layoutParent.context,this.layoutParent,u);t[l.orient]=f,await f.initializeChildren()}},o=async(a,c,u)=>{const l=i(a,c);if(l&&(l.grid||l.chromGrid)){const f=new wT(l,a.scaleResolution.type,this.layoutParent.context,this.layoutParent,u);r[l.orient]=f,await f.initializeChildren()}};for(const a of["x","y"])if(e.needsAxes[a]){const c=e.resolutions.axis[a];if(!c)continue;await s(c,a,e)}for(const a of["x","y"])if(e.needsAxes[a]&&e.getConfiguredOrDefaultResolution(a,"axis")!="excluded"){const c=e.getAxisResolution(a);if(!c)continue;await o(c,a,e)}if(e instanceof Ri){for(const a of e)for(const[c,u]of Object.entries(a.resolutions.axis)){const l=u.getAxisProps();l&&l.orient&&await s(u,c,a)}for(const a of e)for(const[c,u]of Object.entries(a.resolutions.axis)){const l=u.getAxisProps();l&&!l.orient&&await s(u,c,a)}}[...Object.values(t),...Object.values(r)].forEach(a=>a.visit(c=>{c instanceof ft&&c.resolve("scale")}))}getOverhang(){const e=t=>{const r=this.axes[t];return r?Math.max(r.getPerpendicularSize()+(r.axisProps.offset??0),0):0};return new We(e("top"),e("right"),e("bottom"),e("left")).add(this.view.getOverhang())}getOverhangAndPadding(){return this.getOverhang().add(this.view.getPadding())}}Iu=new WeakSet,Bx=function(){const e=this.view,t=r=>{this.view.context.glHelper.canvas.style.cursor=r};for(const[r,i]of e.paramMediator.paramConfigs){if(!("select"in i))continue;const s=kc(i.select);if(!Lm(s))continue;const o=s.encodings,a=Object.fromEntries(o.map(A=>{const w=this.view.getScaleResolution(A),S=w==null?void 0:w.scale;if(!S||!Oe(S.type))throw new Error(`No continuous scale found for interval selection param "${r}" on channel "${A}"! Scale type is "${(S==null?void 0:S.type)??"none"}".`);return[A,w]}));if(this.selectionRect)throw new Error("Only one interval selection per container is currently allowed!");let c=!1,u=!1,l=!1,f=null;const d=(A,w)=>Object.fromEntries(o.map(S=>[S,[Math.min(A[S],w[S]),Math.max(A[S],w[S])]])),h=e.paramMediator.createExpression(r),p=e.paramMediator.getSetter(r);i.value&&p({type:"interval",intervals:i.value});const m=()=>{p(Rm(o)),t(null)};this.selectionRect=new PT(this,h,s.mark),this.selectionRect.initializeChildren();const g=A=>{const w={x:0,y:0},S=e.coords.normalizePoint(A.x,A.y,!0);for(const C of o){const v=a[C].scale,T=v.invert(C=="x"?S.x:S.y);w[C]=T+(["index","locus"].includes(v.type)?.5:0)}return w},y=A=>{var T,P,F,k;const{intervals:w}=A,S=(L,U,j)=>{const K=(ce,ie)=>ie==null?null:a[ce].scale(ie),_=K("x",L)??j,te=K("y",U)??j;return e.coords.denormalizePoint(_,te,!0)},C=S((T=w.x)==null?void 0:T[0],(P=w.y)==null?void 0:P[0],0),v=S((F=w.x)==null?void 0:F[1],(k=w.y)==null?void 0:k[1],1);return Ft.create(C.x,C.y,v.x-C.x,v.y-C.y)};e.addInteractionEventListener("mousedown",(A,w)=>{if(w.mouseEvent.button!=0)return;if(f=c?y(h()):null,f)t("grabbing"),u=!0;else{const P=w.point;if(zm(h())&&(u=!0),w.mouseEvent.shiftKey)m(),l=!0;else if(zm(h())){const k=(L,U)=>{e.removeInteractionEventListener("mouseup",k);const j=U.point;P.subtract(j).length<2&&m()};e.addInteractionEventListener("mouseup",k);return}else return}w.stopPropagation();const S=w.point,C=at.fromMouseEvent(w.mouseEvent).subtract(S),v=P=>{const F=at.fromMouseEvent(P).subtract(C);let k;if(f){const L=F.subtract(S),U=f.translate(L.x,L.y);k=d(g(new at(U.x,U.y)),g(new at(U.x2,U.y2)))}else k=d(g(S),g(F));for(const L of o){const U=a[L],{zoomExtent:j,scale:K}=U,_=k[L];if(["index","locus"].includes(K.type)&&(_[0]=Math.ceil(_[0]),_[1]=Math.ceil(_[1])),f){const te=_[1]-_[0],ce=j[0],ie=j[1];_[0]<ce&&(_[0]=ce,_[1]=ce+te),_[1]>ie&&(_[1]=ie,_[0]=ie-te)}else _[0]=Math.max(j[0],_[0]),_[1]=Math.min(j[1],_[1]);_[1]=Math.min(j[1],_[1])}p({type:"interval",intervals:k})},T=()=>{document.removeEventListener("mousemove",v),document.removeEventListener("mouseup",T),l=!1,f&&(t("move"),f=null)};document.addEventListener("mousemove",v),document.addEventListener("mouseup",T)}),e.addInteractionEventListener("click",(A,w)=>{w.mouseEvent.button==0&&u&&(w.stopPropagation(),u=!1)},!0);const x=A=>y8(h(),g(A));e.addInteractionEventListener("dblclick",(A,w)=>{x(w.point)&&(m(),w.stopPropagation())},!0),e.addInteractionEventListener("mousemove",(A,w)=>{x(w.point)?l||(c=!0,f||t("move")):(c=!1,f||t(null))})}};function MT(n){if(n!=null&&n.fill||n!=null&&n.fillOpacity||n!=null&&n.shadowOpacity)return{configurableVisibility:!1,data:{values:[{}]},mark:{color:n.fill,opacity:n.fillOpacity??(n.fill?1:0),type:"rect",clip:!1,tooltip:null,minHeight:1,minOpacity:0,shadowBlur:n.shadowBlur,shadowColor:n.shadowColor,shadowOffsetX:n.shadowOffsetX,shadowOffsetY:n.shadowOffsetY,shadowOpacity:n.shadowOpacity}}}function RT(n){if(!(!n||!n.stroke||n.strokeWidth===0||n.strokeOpacity===0))return{configurableVisibility:!1,resolve:{scale:{x:"excluded",y:"excluded"},axis:{x:"excluded",y:"excluded"}},data:{values:[{x:0,y:0,x2:1,y2:0},{x:1,y:0,x2:1,y2:1},{x:1,y:1,x2:0,y2:1},{x:0,y:1,x2:0,y2:0}]},mark:{size:n.strokeWidth??1,color:n.stroke??"lightgray",strokeCap:"square",opacity:n.strokeOpacity??1,type:"rule",clip:!1,tooltip:null},encoding:{x:{field:"x",type:"quantitative",scale:null},y:{field:"y",type:"quantitative",scale:null},x2:{field:"x2"},y2:{field:"y2"}}}}class OT extends Vo{constructor(t,r,i,s,o,a,c){super(t,r,i,s,o,c);R(this,re);R(this,vs,1/0);R(this,Ss,10);R(this,et,[]);R(this,ei,{});R(this,Es,0);this.spec=t,G(this,Ss,t.spacing??10),G(this,vs,a),G(this,et,[]),this.wrappingFacet=!1}appendChild(t){t.layoutParent??(t.layoutParent=this),E(this,et).push(new Uy(t,this,E(this,Es))),gx(this,Es)._++}setChildren(t){for(const r of E(this,et))O(this,re,Sd).call(this,r);G(this,et,[]);for(const r of t)this.appendChild(r)}replaceChild(t,r){const i=E(this,et).findIndex(s=>s.view==t);if(i>=0)O(this,re,Sd).call(this,E(this,et)[i]),E(this,et)[i]=new Uy(r,this,E(this,Es));else throw new Error("Not my child view!")}get children(){return E(this,et).map(t=>t.view)}get childCount(){return E(this,et).length}async createAxes(){const t=[];for(const r of Dr){const i=this.resolutions.axis[r];if(i){const s=i.getAxisProps();if(s){const o={title:i.getTitle(),orient:ou[r][0],...s},a=new ky(o,i.scaleResolution.type,this.context,this,this);t.push(a.initializeChildren()),E(this,ei)[r]=a}}}return Promise.all([...t,...E(this,et).map(r=>r.createAxes())])}*[Symbol.iterator](){for(const t of E(this,et))yield*t.getChildren();for(const t of Object.values(E(this,ei)))yield t}getOverhang(){return O(this,re,Fx).call(this).union(O(this,re,Pu).call(this))}getSize(){return this._cache("size",()=>new Wn(O(this,re,Cd).call(this,"column"),O(this,re,Cd).call(this,"row")).addPadding(O(this,re,Pu).call(this)))}render(t,r,i={}){if(super.render(t,r,i),!this.isConfiguredVisible())return;this.layoutParent||(r=r.shrink(this.getPadding())),r=r.shrink(O(this,re,Pu).call(this)),t.pushView(this,r);const s={devicePixelRatio:t.getDevicePixelRatio()},o=ny(O(this,re,Ed).call(this,"column"),r.width,s),a=ny(O(this,re,Ed).call(this,"row"),r.height,s),c=new By(E(this,re,ni).length,E(this,vs)??1/0),u=l=>Math.round(l*devicePixelRatio)/devicePixelRatio;for(const[l,f]of E(this,re,ni).entries()){const{view:d,axes:h,gridLines:p,background:m,backgroundStroke:g,title:y,selectionRect:x}=f,[A,w]=c.getCellCoords(l),S=o[O(this,re,Dd).call(this,"column",A)],C=a[O(this,re,Dd).call(this,"row",w)],v=d.getViewportSize(),T=d.getSize(),P=d.getOverhang(),F=S.location-P.left,k=C.location-P.top,L=(De,St)=>(De[St].grow?(St=="width"?S:C).size:De[St].px)+P[St],U=L(v,"width"),j=L(v,"height"),K=L(T,"width"),_=L(T,"height"),te=f.scrollbars.horizontal,ce=f.scrollbars.vertical,ie=te?()=>u(te.viewportOffset):()=>0,Ne=ce?()=>u(ce.viewportOffset):()=>0,ve=new Ft(()=>r.x+F,()=>r.y+k,()=>U,()=>j),Kt=d.isScrollable(),Jt=Kt?new Ft(()=>r.x+F-ie(),()=>r.y+k-Ne(),()=>K,()=>_):ve;f.coords=ve;const rr=i.clipRect?ve.intersect(i.clipRect):ve;m==null||m.render(t,rr,{...i,clipRect:void 0});for(const De of Object.values(p))De.render(t,ve,i);const Ds=LT(d)||Kt;Ds&&d.render(t,Jt,{...i,clipRect:rr}),g==null||g.render(t,rr,{...i,clipRect:void 0});for(const[De,St]of Object.entries(h)){const ut=De=="left"||De=="right"?"vertical":"horizontal",H=f.scrollbars[ut],J=H?ve.modify(ut=="vertical"?{y:()=>Jt.y,height:_}:{x:()=>Jt.x,width:K}):ve,ne=Gy(J,De,St);let M=i.clipRect;H&&(M=ne.intersect(M).intersect(H?ve.modify(ut=="vertical"?{x:-1e5,width:2e5}:{y:-1e5,height:2e5}):void 0)),St.render(t,ne,{...i,clipRect:M})}for(const De of Object.values(E(this,ei))){const ut=De.axisProps.orient;(ut=="left"&&A==0||ut=="right"&&A==c.nCols-1||ut=="top"&&w==0||ut=="bottom"&&w==c.nRows-1)&&De.render(t,Gy(ve.shrink(f.view.getOverhang()),ut,De),i)}Ds||d.render(t,Jt,i),x==null||x.render(t,Jt,i);for(const De of Object.values(f.scrollbars))De.updateScrollbar(ve,Jt),De.render(t,r,i);y==null||y.render(t,ve,i)}t.popView(this)}propagateInteractionEvent(t){if(this.handleInteractionEvent(void 0,t,!0),t.stopped)return;const r=E(this,re,ni).find(s=>s.coords.containsPoint(t.point.x,t.point.y));for(const s of Object.values((r==null?void 0:r.scrollbars)??{}))if(s.coords.containsPoint(t.point.x,t.point.y)&&(s.propagateInteractionEvent(t),t.stopped))return;const i=r==null?void 0:r.view;if(i){if(i.propagateInteractionEvent(t),t.stopped)return;(i instanceof ft||i instanceof Ri)&&xT(t,r.coords,s=>O(this,re,Px).call(this,r.coords,r.view,s),this.context.getCurrentHover(),this.context.animator)}t.stopped||this.handleInteractionEvent(void 0,t,!1)}getDefaultResolution(t,r){return"independent"}}vs=new WeakMap,Ss=new WeakMap,et=new WeakMap,ei=new WeakMap,Es=new WeakMap,re=new WeakSet,ni=function(){return E(this,et).filter(t=>t.view.isConfiguredVisible())},kx=function(){return new By(E(this,re,ni).length,E(this,vs)??1/0)},Sd=function(t){for(const r of t.getChildren())r.disposeSubtree()},Ta=function(t){const r=t=="column"?"width":"height",i=(s,o)=>s.map(a=>{const u=E(this,re,ni)[a].getOverhangAndPadding();return t=="column"?o?u.right:u.left:o?u.bottom:u.top}).reduce((a,c)=>Math.max(a,c),0);return this._cache(`size/directionSizes/${t}`,()=>E(this,re,kx)[t=="column"?"colIndices":"rowIndices"].map(s=>({axisBefore:i(s,0),axisAfter:i(s,1),view:cI(s.map(o=>E(this,re,ni)[o].view.getViewportSize()[r]))})))},Ed=function(t){const r=O(this,re,Ta).call(this,t),i=[];i.push(zo);for(const[s,o]of r.entries())s>0&&i.push({px:E(this,Ss),grow:0}),(s==0||this.wrappingFacet)&&i.push(zo),i.push({px:o.axisBefore,grow:0}),i.push(o.view),i.push({px:o.axisAfter,grow:0}),(s==r.length-1||this.wrappingFacet)&&i.push(zo);return i},Cd=function(t){let r=0,i=0;const s=t=="row"?this.spec.height:this.spec.width;if(s||s===0)return iy(s);const o=O(this,re,Ta).call(this,t);for(const[a,c]of o.entries())a>0&&(i+=E(this,Ss)),(a==0||this.wrappingFacet)&&(i+=0),i+=c.axisBefore,i+=c.view.px??0,r+=c.view.grow??0,i+=c.axisAfter,(a==o.length-1||this.wrappingFacet)&&(i+=0);return{px:i,grow:r}},Dd=function(t,r){return t=="row"&&this.wrappingFacet?1+6*r+2:2+4*r+1},Fx=function(){const t=O(this,re,Ta).call(this,"column"),r=O(this,re,Ta).call(this,"row");return!t.length||!r.length?We.zero():new We(r.at(0).axisBefore,t.at(-1).axisAfter,r.at(-1).axisAfter,t.at(0).axisBefore)},Pu=function(){const t=r=>{const i=xh[r],s=E(this,ei)[i];return(s==null?void 0:s.axisProps.orient)!==r?0:Math.max(s.getPerpendicularSize()+(s.axisProps.offset??0),0)};return new We(t("top"),t("right"),t("bottom"),t("left"))},Px=function(t,r,i){for(const[s,o]of Object.entries(NT(r))){if(o.size<=0)continue;const a=t.normalizePoint(i.x,i.y),c=t.normalizePoint(i.x+i.xDelta,i.y+i.yDelta),u={x:c.x-a.x,y:c.y-a.y};for(const l of o)l.zoom(2**i.zDelta,s=="y"?1-a[s]:a[s],s=="x"?u.x:-u.y)}this.context.animator.requestRender()};function NT(n){const e={x:new Set,y:new Set};return n.visit(t=>{for(const[r,i]of Object.entries(e)){const s=t.getScaleResolution(r);s&&s.isZoomable()&&i.add(s)}}),e}function LT(n){let e=!0;return n.visit(t=>{t instanceof ft&&e&&(e=t.mark.properties.clip===!0)}),e}function Gy(n,e,t){const r=t.axisProps,i=t.getPerpendicularSize();if(e=="bottom")return n.translate(0,n.height+r.offset).modify({height:i});if(e=="top")return n.translate(0,-i-r.offset).modify({height:i});if(e=="left")return n.translate(-i-r.offset,0).modify({width:i});if(e=="right")return n.translate(n.width+r.offset,0).modify({width:i})}class wh extends OT{constructor(e,t,r,i,s){super(e,t,r,i,s,Eh(e)?e.columns:au(e)?1:1/0),this.spec=e}async initializeChildren(){const e=this.spec,t=Eh(e)?e.concat:au(e)?e.vconcat:e.hconcat;this.setChildren(await Promise.all(t.map((r,i)=>this.context.createOrImportView(r,this,this,"grid"+i)))),await this.createAxes()}getDefaultResolution(e,t){return t=="axis"?"independent":au(this.spec)&&e==="x"||_y(this.spec)&&e==="y"?"shared":"independent"}}const Hy="viewRoot";class zT{constructor(e={}){R(this,Cs,new Map);this.options={allowImport:!0,wrapRoot:!0,...e};const t=r=>(i,s,o,a,c)=>new r(i,s,o,a,i.name??c);this.addViewType(Sh,t(Ri)),this.addViewType(vh,t(ft)),this.addViewType(au,t(wh)),this.addViewType(_y,t(wh)),this.addViewType(Eh,t(wh)),this.addViewType(HT,()=>{throw new Error("SampleView is not supported by the @genome-spy/core package. Use @genome-spy/app instead!")})}addViewType(e,t){E(this,Cs).set(e,t)}createView(e,t,r,i,s){for(const[o,a]of E(this,Cs))if(o(e))return a(e,t,r,i,s);throw new Error("Invalid spec, cannot figure out the view type from the properties: "+JSON.stringify([...Object.keys(e)]))}isViewSpec(e){const t=[...E(this,Cs).keys()].filter(r=>r(e));if(t.length>1)throw new Error("Ambiguous spec. Cannot create a view!");return t.length==1}async createOrImportView(e,t,r,i,s,o){let a;if(GT(e)){let l;if("url"in e.import)if(this.options.allowImport)l=await yI(e,i.getBaseUrl(),t);else throw new Qn("Importing views is not allowed!",r);else if("template"in e.import)l=Vy(e.import.template,i);else throw new Error("Invalid import: "+JSON.stringify(e));o==null||o(l),UT(l,e),a=l}else a=e;const c=l=>{var f;return(f=l==null?void 0:l.params)==null?void 0:f.some(d=>Pm(d)&&kc(d.select).type=="interval")};!i&&this.options.wrapRoot&&(vh(a)||Sh(a)||c(a))&&s===Hy&&(a={name:"implicitRoot",vconcat:[a]});const u=this.createView(a,t,r,i,s);return u instanceof Vo&&await u.initializeChildren(),u}}Cs=new WeakMap;function Vy(n,e){var r,i;const t=(i=(r=e.spec)==null?void 0:r.templates)==null?void 0:i[n];if(t)return structuredClone(t);if(e.dataParent)return Vy(n,e.dataParent);throw new Error(`Cannot find template "${n}" in current view or its ancestors!`)}function UT(n,e){e.name!=null&&(n.name=e.name);const t=Ue(e.params)?e.params:Ge(e.params)?Object.entries(e.params).map(([r,i])=>({name:r,value:i})):[];if(t.length){n.params??(n.params=[]);for(const r of t){const i=n.params.findIndex(s=>s.name==r.name);i>=0&&(n.params[i]=r)}for(const r of t)n.params.some(i=>i.name==r.name)||n.params.push(r)}}function vh(n){return"mark"in n&&(me(n.mark)||Ge(n.mark))}function Sh(n){return"layer"in n&&Ge(n.layer)}function GT(n){return"import"in n}function au(n){return"vconcat"in n&&Ue(n.vconcat)}function _y(n){return"hconcat"in n&&Ue(n.hconcat)}function Eh(n){return"concat"in n&&Ue(n.concat)}function HT(n){return"samples"in n&&Ge(n.samples)&&"spec"in n&&Ge(n.spec)}function VT(n){const e=Math.floor(Math.random()*16777215).toString(16),t=[];for(const r of n.paramConfigs.values()){if(!p8(r))continue;const i=r.bind;if(!i||!("input"in i))continue;const s=r.name,o=n.getSetter(s),a=n.getValue(s),c=i.name??s,u=i.debounce?iu(o,i.debounce,!1):o,l=`${e}-param-${s}`;if(i.input=="range")t.push(ye`<label for=${l}>${c}</label>
                     <div>
                         <input
-                            id=${u}
+                            id=${l}
                             type="range"
-                            min=${o.min??0}
-                            max=${o.max??100}
-                            step=${o.step??ri(o.min,o.max,100)}
+                            min=${i.min??0}
+                            max=${i.max??100}
+                            step=${i.step??pr(i.min,i.max,100)}
                             .value=${a}
-                            @input=${f=>{l(f.target.valueAsNumber),f.target.nextElementSibling.textContent=f.target.valueAsNumber}}
+                            @input=${f=>{u(f.target.valueAsNumber),f.target.nextElementSibling.textContent=f.target.valueAsNumber}}
                         /><span>${a}</span>
-                    </div>`);else if(o.input=="checkbox")n.push(ot`<label for=${u}>${c}</label>
+                    </div>`);else if(i.input=="checkbox")t.push(ye`<label for=${l}>${c}</label>
                     <input
-                        id=${u}
+                        id=${l}
                         type="checkbox"
                         ?checked=${a}
-                        @input=${f=>l(f.target.checked)}
-                    />`);else if(o.input=="radio")n.push(ot`<span class="label">${c}</span>
+                        @input=${f=>u(f.target.checked)}
+                    />`);else if(i.input=="radio")t.push(ye`<span class="label">${c}</span>
                     <div class="radio-group">
-                        ${o.options.map((f,d)=>{var h;return ot`<label>
+                        ${i.options.map((f,d)=>{var h;return ye`<label>
                                     <input
                                         type="radio"
-                                        name=${i}
+                                        name=${s}
                                         value=${f}
                                         .checked=${a==f}
-                                        @input=${p=>l(p.target.value)}
-                                    />${((h=o.labels)==null?void 0:h[d])??f}</label
+                                        @input=${p=>u(p.target.value)}
+                                    />${((h=i.labels)==null?void 0:h[d])??f}</label
                                 >`})}
-                    </div>`);else if(o.input=="select")n.push(ot`<label for=${u}>${c}</label>
+                    </div>`);else if(i.input=="select")t.push(ye`<label for=${l}>${c}</label>
                     <select
-                        id=${u}
-                        @input=${f=>l(f.target.value)}
+                        id=${l}
+                        @input=${f=>u(f.target.value)}
                     >
-                        ${o.options.map((f,d)=>{var h;return ot`<option
+                        ${i.options.map((f,d)=>{var h;return ye`<option
                                     value=${f}
                                     ?selected=${a==f}
                                 >
-                                    ${((h=o.labels)==null?void 0:h[d])??f}
+                                    ${((h=i.labels)==null?void 0:h[d])??f}
                                 </option>`})}
-                    </select> `);else if(o.input=="text"||o.input=="number"||o.input=="color")n.push(ot`<label for=${u}>${c}</label>
+                    </select> `);else if(i.input=="text"||i.input=="number"||i.input=="color")t.push(ye`<label for=${l}>${c}</label>
                     <div>
                         <input
-                            id=${u}
-                            type=${o.input}
-                            placeholder=${o.placeholder??""}
-                            autocomplete=${o.autocomplete??"off"}
+                            id=${l}
+                            type=${i.input}
+                            placeholder=${i.placeholder??""}
+                            autocomplete=${i.autocomplete??"off"}
                             .value=${a}
                             @focus=${f=>f.target.select()}
-                            @input=${f=>{l(o.input=="number"?f.target.valueAsNumber:f.target.value)}}
+                            @input=${f=>{u(i.input=="number"?f.target.valueAsNumber:f.target.value)}}
                         />
-                    </div>`);else throw new Error("Unsupported input type: "+o.input);o.description&&n.push(ot`<div class="description">${o.description}</div>`)}return n}ff("fasta",g_);class m2{constructor(e,n,r={}){he(this,gn);this.container=e,this.options=r,r.inputBindingContainer??(r.inputBindingContainer="default"),this._destructionCallbacks=[],this.spec=n,this.viewFactory=new $_,this.namedDataProviders=[],this.animator=new c_(()=>this.renderAll()),this.genomeStore=void 0,this.viewVisibilityPredicate=o=>o.isVisibleInSpec(),this._renderingContext=void 0,this._pickingContext=void 0,this._dirtyPickingBuffer=!1,this._currentHover=void 0,this._wheelInertia=new m_(this.animator),this._keyboardListeners=new Map,this._eventListeners=new Map,this._extraBroadcastListeners=new Map,this.tooltipHandlers={default:I_,refseqgene:w_,...r.tooltipHandlers??{}},this.viewRoot=void 0,this._loadingViews=new Map,this._inputBindingContainer=void 0,this._mouseDownCoords=void 0,this.dpr=window.devicePixelRatio}registerNamedDataProvider(e){this.namedDataProviders.unshift(e)}getNamedDataFromProvider(e){for(const n of this.namedDataProviders){const r=n(e);if(r)return r}}updateNamedData(e,n){const r=this.viewRoot.context.dataFlow.findNamedDataSource(e);if(!r)throw new Error("No such named data source: "+e);r.dataSource.updateDynamicData(n),sd(r.hosts),this.animator.requestRender()}broadcast(e,n){var o;const r={type:e,payload:n};this.viewRoot.visit(i=>i.handleBroadcast(r)),(o=this._extraBroadcastListeners.get(e))==null||o.forEach(i=>i(r))}_updateLoadingIndicators(){const e=[],n=()=>[...this._loadingViews.values()].some(r=>r.status=="loading"||r.status=="error");for(const[r,o]of this._loadingViews){const i=r.coords;if(i){const s={left:`${i.x}px`,top:`${i.y}px`,width:`${i.width}px`,height:`${i.height}px`};e.push(ot`<div style=${hS(s)}>
-                        <div class=${o.status}>
-                            ${o.status=="error"?ot`<span
+                    </div>`);else throw new Error("Unsupported input type: "+i.input);i.description&&t.push(ye`<div class="description">${i.description}</div>`)}return t}hl("fasta",eT);class jy{constructor(e,t,r={}){R(this,vt);this.container=e,this.options=r,r.inputBindingContainer??(r.inputBindingContainer="default"),this._destructionCallbacks=[],this.spec=t,this.viewFactory=new zT,this.namedDataProviders=[],this.animator=new q9(()=>this.renderAll()),this.genomeStore=void 0,this.viewVisibilityPredicate=i=>i.isVisibleInSpec(),this._renderingContext=void 0,this._pickingContext=void 0,this._dirtyPickingBuffer=!1,this._currentHover=void 0,this._wheelInertia=new tT(this.animator),this._keyboardListeners=new Map,this._eventListeners=new Map,this._extraBroadcastListeners=new Map,this.tooltipHandlers={default:fT,refseqgene:iT,...r.tooltipHandlers??{}},this.viewRoot=void 0,this._loadingViews=new Map,this._inputBindingContainer=void 0,this._mouseDownCoords=void 0,this.dpr=window.devicePixelRatio}registerNamedDataProvider(e){this.namedDataProviders.unshift(e)}getNamedDataFromProvider(e){for(const t of this.namedDataProviders){const r=t(e);if(r)return r}}updateNamedData(e,t){const r=this.viewRoot.context.dataFlow.findNamedDataSource(e);if(!r)throw new Error("No such named data source: "+e);r.dataSource.updateDynamicData(t),this.animator.requestRender()}broadcast(e,t){var i;const r={type:e,payload:t};this.viewRoot.visit(s=>s.handleBroadcast(r)),(i=this._extraBroadcastListeners.get(e))==null||i.forEach(s=>s(r))}_updateLoadingIndicators(){const e=[],t=()=>[...this._loadingViews.values()].some(r=>r.status=="loading"||r.status=="error");for(const[r,i]of this._loadingViews){const s=r.coords;if(s){const o={left:`${s.x}px`,top:`${s.y}px`,width:`${s.width}px`,height:`${s.height}px`};e.push(ye`<div style=${Qv(o)}>
+                        <div class=${i.status}>
+                            ${i.status=="error"?ye`<span
                                       >Loading
-                                      failed${o.detail?ot`: ${o.detail}`:pt}</span
-                                  >`:ot`
-                                      <img src="${dS}" alt="" />
+                                      failed${i.detail?ye`: ${i.detail}`:Ee}</span
+                                  >`:ye`
+                                      <img src="${Wv}" alt="" />
                                       <span>Loading...</span>
                                   `}
                         </div>
-                    </div>`)}}n()?this.loadingIndicatorsElement.style.display="block":setTimeout(()=>{n()||(this.loadingIndicatorsElement.style.display="none")},3e3),Es(e,this.loadingIndicatorsElement)}destroy(){var n;const e=j(this,gn,_u);this.container.classList.remove("genome-spy"),e.classList.remove("loading");for(const[r,o]of this._keyboardListeners)for(const i of o)document.removeEventListener(r,i);for(this._destructionCallbacks.forEach(r=>r()),this._glHelper.finalize(),(n=this._inputBindingContainer)==null||n.remove();this.container.firstChild;)this.container.firstChild.remove()}async _prepareViewsAndData(){this.spec.genome&&(this.genomeStore=new l_(this.spec.baseUrl),await this.genomeStore.initialize(this.spec.genome));const e=this,n={dataFlow:new Qb,glHelper:this._glHelper,animator:this.animator,genomeStore:this.genomeStore,fontManager:new h_(this._glHelper),requestLayoutReflow:()=>{},updateTooltip:this.updateTooltip.bind(this),getNamedDataFromProvider:this.getNamedDataFromProvider.bind(this),getCurrentHover:()=>this._currentHover,setDataLoadingStatus:(c,l,u)=>{this._loadingViews.set(c,{status:l,detail:u}),this._updateLoadingIndicators()},addKeyboardListener:(c,l)=>{document.addEventListener(c,l);let u=this._keyboardListeners.get(c);u||(u=[],this._keyboardListeners.set(c,u)),u.push(l)},addBroadcastListener(c,l){const u=e._extraBroadcastListeners;let f=u.get(c);f||(f=new Set,u.set(c,f)),f.add(l)},removeBroadcastListener(c,l){var f;(f=e._extraBroadcastListeners.get(c))==null||f.delete(l)},isViewConfiguredVisible:e.viewVisibilityPredicate,isViewSpec:c=>e.viewFactory.isViewSpec(c),createOrImportView:async function(c,l,u,f,d){return e.viewFactory.createOrImportView(c,n,l,u,f,d)},highlightView:c=>{var l;if((l=this.container.querySelector(".view-highlight"))==null||l.remove(),c){const u=c.coords;if(u){const f=document.createElement("div");f.className="view-highlight",f.style.position="absolute",f.style.left=u.x+"px",f.style.top=u.y+"px",f.style.width=u.width+"px",f.style.height=u.height+"px",f.style.border="1px solid green",f.style.backgroundColor="rgba(0, 255, 0, 0.1)",f.style.pointerEvents="none",this.container.appendChild(f)}}}},r=this.spec;r.datasets&&this.registerNamedDataProvider(c=>r.datasets[c]),this.viewRoot=await n.createOrImportView(r,null,null,d2),j(this,gn,_u).style.flexGrow=this.viewRoot.getSize().height.grow>0?"1":"0",pe(this,gn,$v).call(this),$k(this.viewRoot),e_(this.viewRoot);const o=this.viewRoot.getDescendants();o.forEach(c=>c.configureViewOpacity()),this._glHelper.invalidateSize(),pe(this,gn,eA).call(this);const i=o.filter(c=>c instanceof en),s=Yk(this.viewRoot,n.dataFlow);Jk(s),this.broadcast("dataFlowBuilt",s),i.forEach(c=>c.mark.initializeEncoders());const a=Promise.all(i.map(c=>c.mark.initializeGraphics()));for(const c of i)s.addObserver(l=>{c.mark.initializeData();try{c.mark.updateGraphicsData()}catch(u){throw u.view=c,u}n.animator.requestRender()},c);await n.fontManager.waitUntilReady(),s.initialize(),await Promise.all(s.dataSources.map(c=>c.load())),sd(this.viewRoot),this.broadcast("dataLoaded"),await a;for(const c of i)c.mark.finalizeGraphicsInitialization();n.requestLayoutReflow=this.computeLayout.bind(this),this.viewRoot.visit(c=>Ul(c,"size")),this._glHelper.invalidateSize()}async launch(){try{return pe(this,gn,tA).call(this),await this._prepareViewsAndData(),this.registerMouseEvents(),this.computeLayout(),this.animator.requestRender(),!0}catch(e){const n=`${e.view?`At "${e.view.getPathString()}": `:""}${e.toString()}`;return console.error(e.stack),iR(this.container,n),!1}finally{j(this,gn,_u).classList.remove("loading"),window.setTimeout(()=>{this.loadingMessageElement.style.display="none"},2e3)}}registerMouseEvents(){const e=this._glHelper.canvas;let n=performance.now(),r=!1;const o=i=>{var c,l;const s=performance.now(),a=s-n<200;if(i instanceof MouseEvent){const u=e.getBoundingClientRect(),f=new Xt(i.clientX-u.left-e.clientLeft,i.clientY-u.top-e.clientTop);i.type=="mousemove"&&!a&&(this.tooltip.handleMouseMove(i),this._tooltipUpdateRequested=!1,i.buttons==0&&!s2()&&(this.renderPickingFramebuffer(),this._handlePicking(f.x,f.y)));const d=h=>{this.viewRoot.propagateInteractionEvent(new i_(f,h)),this._tooltipUpdateRequested||this.tooltip.clear()};if(i.type!="wheel"&&this._wheelInertia.cancel(),(i.type=="mousedown"||i.type=="mouseup")&&!s2())this.renderPickingFramebuffer();else if(i.type=="wheel"){n=s,this._tooltipUpdateRequested=!1;const h=i;if(Math.abs(h.deltaX)>Math.abs(h.deltaY))this._currentHover=null,this._wheelInertia.cancel();else{const p=y_(h);this._wheelInertia.setMomentum(h.deltaY*(h.deltaMode?80:1),y=>{const v=new WheelEvent("wheel",{...p,deltaMode:0,deltaX:0,deltaY:y});d(v)}),h.preventDefault();return}}if(i.type=="click"){if(r)return;const h=this._currentHover?{type:i.type,viewPath:this._currentHover.mark.unitView.getLayoutAncestors().map(p=>p.name).reverse(),datum:this._currentHover.datum}:{type:i.type,viewPath:null,datum:null};(c=this._eventListeners.get("click"))==null||c.forEach(p=>p(h))}(i.type!="click"||((l=this._mouseDownCoords)==null?void 0:l.subtract(Xt.fromMouseEvent(i)).length)<3)&&d(i)}};["mousedown","mouseup","wheel","click","mousemove","gesturechange","contextmenu","dblclick"].forEach(i=>e.addEventListener(i,o)),e.addEventListener("mousedown",i=>{this._mouseDownCoords=Xt.fromMouseEvent(i),this.tooltip.sticky?(this.tooltip.sticky=!1,this.tooltip.clear(),r=!0):r=!1;const s=()=>{document.addEventListener("mouseup",()=>this.tooltip.popEnabledState(),{once:!0}),this.tooltip.pushEnabledState(!1)};if(i.button==2||i.shiftKey||i.ctrlKey||i.metaKey)s();else if(this.tooltip.visible){const a=setTimeout(()=>{r=!0,this.tooltip.sticky=!0},400),c=()=>clearTimeout(a);document.addEventListener("mouseup",c,{once:!0}),document.addEventListener("mousemove",c,{once:!0})}}),e.addEventListener("dragstart",i=>i.stopPropagation())}_handlePicking(e,n){var s;const r=this.dpr,o=PT(this._glHelper.gl,this._glHelper._pickingBufferInfo,e*r,n*r),i=o[0]|o[1]<<8|o[2]<<16|o[3]<<24;if(i==0){this._currentHover=null;return}if(i!==((s=this._currentHover)==null?void 0:s.uniqueId)&&(this._currentHover=null),this._currentHover||this.viewRoot.visit(a=>{if(a instanceof en){if(a.mark.isPickingParticipant()&&[...a.facetCoords.values()].some(c=>c.containsPoint(e,n))){const c=a.getCollector().findDatumByUniqueId(i);c&&(this._currentHover={mark:a.mark,datum:c,uniqueId:i})}if(this._currentHover)return Ia}}),this._currentHover){const a=this._currentHover.mark;this.updateTooltip(this._currentHover.datum,async c=>{if(!a.isPickingParticipant())return;const l=a.properties.tooltip;if(l!==null){const u=(l==null?void 0:l.handler)??"default",f=this.tooltipHandlers[u];if(!f)throw new Error("No such tooltip handler: "+u);return f(c,a,l==null?void 0:l.params)}})}}updateTooltip(e,n){if(!this._tooltipUpdateRequested||!e)this.tooltip.updateWithDatum(e,n),this._tooltipUpdateRequested=!0;else throw new Error("Tooltip has already been updated! 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g.insert=0,K===c?(Se(g,!0),g.strm.avail_out===0?fe:L):(g.strstart>g.block_start&&(Se(g,!1),g.strm.avail_out===0),ee)}function zt(g,K){for(var $,R;;){if(g.lookahead<de){if($e(g),g.lookahead<de&&K===i)return ee;if(g.lookahead===0)break}if($=0,g.lookahead>=ce&&(g.ins_h=(g.ins_h<<g.hash_shift^g.window[g.strstart+ce-1])&g.hash_mask,$=g.prev[g.strstart&g.w_mask]=g.head[g.ins_h],g.head[g.ins_h]=g.strstart),$!==0&&g.strstart-$<=g.w_size-de&&(g.match_length=It(g,$)),g.match_length>=ce)if(R=e._tr_tally(g,g.strstart-g.match_start,g.match_length-ce),g.lookahead-=g.match_length,g.match_length<=g.max_lazy_match&&g.lookahead>=ce){g.match_length--;do g.strstart++,g.ins_h=(g.ins_h<<g.hash_shift^g.window[g.strstart+ce-1])&g.hash_mask,$=g.prev[g.strstart&g.w_mask]=g.head[g.ins_h],g.head[g.ins_h]=g.strstart;while(--g.match_length!==0);g.strstart++}else g.strstart+=g.match_length,g.match_length=0,g.ins_h=g.window[g.strstart],g.ins_h=(g.ins_h<<g.hash_shift^g.window[g.strstart+1])&g.hash_mask;else 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x(){this.strm=null,this.status=0,this.pending_buf=null,this.pending_buf_size=0,this.pending_out=0,this.pending=0,this.wrap=0,this.gzhead=null,this.gzindex=0,this.method=_,this.last_flush=-1,this.w_size=0,this.w_bits=0,this.w_mask=0,this.window=null,this.window_size=0,this.prev=null,this.head=null,this.ins_h=0,this.hash_size=0,this.hash_bits=0,this.hash_mask=0,this.hash_shift=0,this.block_start=0,this.match_length=0,this.prev_match=0,this.match_available=0,this.strstart=0,this.match_start=0,this.lookahead=0,this.prev_length=0,this.max_chain_length=0,this.max_lazy_match=0,this.level=0,this.strategy=0,this.good_match=0,this.nice_match=0,this.dyn_ltree=new t.Buf16(se*2),this.dyn_dtree=new t.Buf16((2*Q+1)*2),this.bl_tree=new t.Buf16((2*oe+1)*2),Be(this.dyn_ltree),Be(this.dyn_dtree),Be(this.bl_tree),this.l_desc=null,this.d_desc=null,this.bl_desc=null,this.bl_count=new t.Buf16(ae+1),this.heap=new t.Buf16(2*Y+1),Be(this.heap),this.heap_len=0,this.heap_max=0,this.depth=new t.Buf16(2*Y+1),Be(this.depth),this.l_buf=0,this.lit_bufsize=0,this.last_lit=0,this.d_buf=0,this.opt_len=0,this.static_len=0,this.matches=0,this.insert=0,this.bi_buf=0,this.bi_valid=0}function z(g){var K;return!g||!g.state?te(g,d):(g.total_in=g.total_out=0,g.data_type=I,K=g.state,K.pending=0,K.pending_out=0,K.wrap<0&&(K.wrap=-K.wrap),K.status=K.wrap?me:q,g.adler=K.wrap===2?0:1,K.last_flush=i,e._tr_init(K),u)}function V(g){var K=z(g);return K===u&&O(g.state),K}function ue(g,K){return!g||!g.state||g.state.wrap!==2?d:(g.state.gzhead=K,u)}function G(g,K,$,R,H,Z){if(!g)return d;var Te=1;if(K===y&&(K=6),R<0?(Te=0,R=-R):R>15&&(Te=2,R-=16),H<1||H>B||$!==_||R<8||R>15||K<0||K>9||Z<0||Z>S)return te(g,d);R===8&&(R=9);var be=new x;return g.state=be,be.strm=g,be.wrap=Te,be.gzhead=null,be.w_bits=R,be.w_size=1<<be.w_bits,be.w_mask=be.w_size-1,be.hash_bits=H+7,be.hash_size=1<<be.hash_bits,be.hash_mask=be.hash_size-1,be.hash_shift=~~((be.hash_bits+ce-1)/ce),be.window=new t.Buf8(be.w_size*2),be.head=new t.Buf16(be.hash_size),be.prev=new t.Buf16(be.w_size),be.lit_bufsize=1<<H+6,be.pending_buf_size=be.lit_bufsize*4,be.pending_buf=new t.Buf8(be.pending_buf_size),be.d_buf=1*be.lit_bufsize,be.l_buf=3*be.lit_bufsize,be.level=K,be.strategy=Z,be.method=$,V(g)}function X(g,K){return G(g,K,_,N,F,E)}function T(g,K){var $,R,H,Z;if(!g||!g.state||K>l||K<0)return g?te(g,d):d;if(R=g.state,!g.output||!g.input&&g.avail_in!==0||R.status===W&&K!==c)return te(g,g.avail_out===0?p:d);if(R.strm=g,$=R.last_flush,R.last_flush=K,R.status===me)if(R.wrap===2)g.adler=0,Re(R,31),Re(R,139),Re(R,8),R.gzhead?(Re(R,(R.gzhead.text?1:0)+(R.gzhead.hcrc?2:0)+(R.gzhead.extra?4:0)+(R.gzhead.name?8:0)+(R.gzhead.comment?16:0)),Re(R,R.gzhead.time&255),Re(R,R.gzhead.time>>8&255),Re(R,R.gzhead.time>>16&255),Re(R,R.gzhead.time>>24&255),Re(R,R.level===9?2:R.strategy>=b||R.level<2?4:0),Re(R,R.gzhead.os&255),R.gzhead.extra&&R.gzhead.extra.length&&(Re(R,R.gzhead.extra.length&255),Re(R,R.gzhead.extra.length>>8&255)),R.gzhead.hcrc&&(g.adler=r(g.adler,R.pending_buf,R.pending,0)),R.gzindex=0,R.status=Ee):(Re(R,0),Re(R,0),Re(R,0),Re(R,0),Re(R,0),Re(R,R.level===9?2:R.strategy>=b||R.level<2?4:0),Re(R,D),R.status=q);else{var Te=_+(R.w_bits-8<<4)<<8,be=-1;R.strategy>=b||R.level<2?be=0:R.level<6?be=1:R.level===6?be=2:be=3,Te|=be<<6,R.strstart!==0&&(Te|=Ce),Te+=31-Te%31,R.status=q,dt(R,Te),R.strstart!==0&&(dt(R,g.adler>>>16),dt(R,g.adler&65535)),g.adler=1}if(R.status===Ee)if(R.gzhead.extra){for(H=R.pending;R.gzindex<(R.gzhead.extra.length&65535)&&!(R.pending===R.pending_buf_size&&(R.gzhead.hcrc&&R.pending>H&&(g.adler=r(g.adler,R.pending_buf,R.pending-H,H)),ve(g),H=R.pending,R.pending===R.pending_buf_size));)Re(R,R.gzhead.extra[R.gzindex]&255),R.gzindex++;R.gzhead.hcrc&&R.pending>H&&(g.adler=r(g.adler,R.pending_buf,R.pending-H,H)),R.gzindex===R.gzhead.extra.length&&(R.gzindex=0,R.status=De)}else R.status=De;if(R.status===De)if(R.gzhead.name){H=R.pending;do{if(R.pending===R.pending_buf_size&&(R.gzhead.hcrc&&R.pending>H&&(g.adler=r(g.adler,R.pending_buf,R.pending-H,H)),ve(g),H=R.pending,R.pending===R.pending_buf_size)){Z=1;break}R.gzindex<R.gzhead.name.length?Z=R.gzhead.name.charCodeAt(R.gzindex++)&255:Z=0,Re(R,Z)}while(Z!==0);R.gzhead.hcrc&&R.pending>H&&(g.adler=r(g.adler,R.pending_buf,R.pending-H,H)),Z===0&&(R.gzindex=0,R.status=Ge)}else R.status=Ge;if(R.status===Ge)if(R.gzhead.comment){H=R.pending;do{if(R.pending===R.pending_buf_size&&(R.gzhead.hcrc&&R.pending>H&&(g.adler=r(g.adler,R.pending_buf,R.pending-H,H)),ve(g),H=R.pending,R.pending===R.pending_buf_size)){Z=1;break}R.gzindex<R.gzhead.comment.length?Z=R.gzhead.comment.charCodeAt(R.gzindex++)&255:Z=0,Re(R,Z)}while(Z!==0);R.gzhead.hcrc&&R.pending>H&&(g.adler=r(g.adler,R.pending_buf,R.pending-H,H)),Z===0&&(R.status=Ve)}else R.status=Ve;if(R.status===Ve&&(R.gzhead.hcrc?(R.pending+2>R.pending_buf_size&&ve(g),R.pending+2<=R.pending_buf_size&&(Re(R,g.adler&255),Re(R,g.adler>>8&255),g.adler=0,R.status=q)):R.status=q),R.pending!==0){if(ve(g),g.avail_out===0)return R.last_flush=-1,u}else if(g.avail_in===0&&le(K)<=le($)&&K!==c)return te(g,p);if(R.status===W&&g.avail_in!==0)return te(g,p);if(g.avail_in!==0||R.lookahead!==0||K!==i&&R.status!==W){var xe=R.strategy===b?k(R,K):R.strategy===A?Ut(R,K):w[R.level].func(R,K);if((xe===fe||xe===L)&&(R.status=W),xe===ee||xe===fe)return g.avail_out===0&&(R.last_flush=-1),u;if(xe===J&&(K===s?e._tr_align(R):K!==l&&(e._tr_stored_block(R,0,0,!1),K===a&&(Be(R.head),R.lookahead===0&&(R.strstart=0,R.block_start=0,R.insert=0))),ve(g),g.avail_out===0))return R.last_flush=-1,u}return K!==c?u:R.wrap<=0?f:(R.wrap===2?(Re(R,g.adler&255),Re(R,g.adler>>8&255),Re(R,g.adler>>16&255),Re(R,g.adler>>24&255),Re(R,g.total_in&255),Re(R,g.total_in>>8&255),Re(R,g.total_in>>16&255),Re(R,g.total_in>>24&255)):(dt(R,g.adler>>>16),dt(R,g.adler&65535)),ve(g),R.wrap>0&&(R.wrap=-R.wrap),R.pending!==0?u:f)}function re(g){var K;return!g||!g.state?d:(K=g.state.status,K!==me&&K!==Ee&&K!==De&&K!==Ge&&K!==Ve&&K!==q&&K!==W?te(g,d):(g.state=null,K===q?te(g,h):u))}function _e(g,K){var $=K.length,R,H,Z,Te,be,xe,Ue,mn;if(!g||!g.state||(R=g.state,Te=R.wrap,Te===2||Te===1&&R.status!==me||R.lookahead))return d;for(Te===1&&(g.adler=n(g.adler,K,$,0)),R.wrap=0,$>=R.w_size&&(Te===0&&(Be(R.head),R.strstart=0,R.block_start=0,R.insert=0),mn=new t.Buf8(R.w_size),t.arraySet(mn,K,$-R.w_size,R.w_size,0),K=mn,$=R.w_size),be=g.avail_in,xe=g.next_in,Ue=g.input,g.avail_in=$,g.next_in=0,g.input=K,$e(R);R.lookahead>=ce;){H=R.strstart,Z=R.lookahead-(ce-1);do 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p(A);this.options=e.assign({level:f,method:h,chunkSize:16384,windowBits:15,memLevel:8,strategy:d,to:""},A||{});var S=this.options;S.raw&&S.windowBits>0?S.windowBits=-S.windowBits:S.gzip&&S.windowBits>0&&S.windowBits<16&&(S.windowBits+=16),this.err=0,this.msg="",this.ended=!1,this.chunks=[],this.strm=new o,this.strm.avail_out=0;var E=t.deflateInit2(this.strm,S.level,S.method,S.windowBits,S.memLevel,S.strategy);if(E!==c)throw new Error(r[E]);if(S.header&&t.deflateSetHeader(this.strm,S.header),S.dictionary){var I;if(typeof S.dictionary=="string"?I=n.string2buf(S.dictionary):i.call(S.dictionary)==="[object ArrayBuffer]"?I=new Uint8Array(S.dictionary):I=S.dictionary,E=t.deflateSetDictionary(this.strm,I),E!==c)throw new Error(r[E]);this._dict_set=!0}}p.prototype.push=function(A,S){var E=this.strm,I=this.options.chunkSize,_,B;if(this.ended)return!1;B=S===~~S?S:S===!0?a:s,typeof A=="string"?E.input=n.string2buf(A):i.call(A)==="[object ArrayBuffer]"?E.input=new 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X;return!G||!G.state?p:(X=G.state,G.total_in=G.total_out=X.total=0,G.msg="",X.wrap&&(G.adler=X.wrap&1),X.mode=S,X.last=0,X.havedict=0,X.dmax=32768,X.head=null,X.hold=0,X.bits=0,X.lencode=X.lendyn=new t.Buf32(Be),X.distcode=X.distdyn=new t.Buf32(ve),X.sane=1,X.back=-1,f)}function $e(G){var X;return!G||!G.state?p:(X=G.state,X.wsize=0,X.whave=0,X.wnext=0,It(G))}function kt(G,X){var T,re;return!G||!G.state||(re=G.state,X<0?(T=0,X=-X):(T=(X>>4)+1,X<48&&(X&=15)),X&&(X<8||X>15))?p:(re.window!==null&&re.wbits!==X&&(re.window=null),re.wrap=T,re.wbits=X,$e(G))}function zt(G,X){var T,re;return G?(re=new Jt,G.state=re,re.window=null,T=kt(G,X),T!==f&&(G.state=null),T):p}function et(G){return zt(G,Re)}var Ut=!0,k,m;function w(G){if(Ut){var X;for(k=new t.Buf32(512),m=new 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Ve:for(;U=T.distcode[H&(1<<T.distbits)-1],Me=U>>>24,lt=U>>>16&255,tt=U&65535,!(Me<=Z);){if($===0)break e;$--,H+=re[g++]<<Z,Z+=8}if(!(lt&240)){for(Tt=Me,ke=lt,lr=tt;U=T.distcode[lr+((H&(1<<Tt+ke)-1)>>Tt)],Me=U>>>24,lt=U>>>16&255,tt=U&65535,!(Tt+Me<=Z);){if($===0)break e;$--,H+=re[g++]<<Z,Z+=8}H>>>=Tt,Z-=Tt,T.back+=Tt}if(H>>>=Me,Z-=Me,T.back+=Me,lt&64){G.msg="invalid distance code",T.mode=D;break}T.offset=tt,T.extra=lt&15,T.mode=q;case q:if(T.extra){for(rn=T.extra;Z<rn;){if($===0)break e;$--,H+=re[g++]<<Z,Z+=8}T.offset+=H&(1<<T.extra)-1,H>>>=T.extra,Z-=T.extra,T.back+=T.extra}if(T.offset>T.dmax){G.msg="invalid distance too far back",T.mode=D;break}T.mode=W;case W:if(R===0)break e;if(xe=be-R,T.offset>xe){if(xe=T.offset-xe,xe>T.whave&&T.sane){G.msg="invalid distance too far back",T.mode=D;break}xe>T.wnext?(xe-=T.wnext,Ue=T.wsize-xe):Ue=T.wnext-xe,xe>T.length&&(xe=T.length),mn=T.window}else mn=_e,Ue=K-T.offset,xe=T.length;xe>R&&(xe=R),R-=xe,T.length-=xe;do 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fn.inflateReset=$e,fn.inflateReset2=kt,fn.inflateResetKeep=It,fn.inflateInit=et,fn.inflateInit2=zt,fn.inflate=x,fn.inflateEnd=z,fn.inflateGetHeader=V,fn.inflateSetDictionary=ue,fn.inflateInfo="pako inflate (from Nodeca project)",fn}var _d,U2;function G2(){return U2||(U2=1,_d={Z_NO_FLUSH:0,Z_PARTIAL_FLUSH:1,Z_SYNC_FLUSH:2,Z_FULL_FLUSH:3,Z_FINISH:4,Z_BLOCK:5,Z_TREES:6,Z_OK:0,Z_STREAM_END:1,Z_NEED_DICT:2,Z_ERRNO:-1,Z_STREAM_ERROR:-2,Z_DATA_ERROR:-3,Z_BUF_ERROR:-5,Z_NO_COMPRESSION:0,Z_BEST_SPEED:1,Z_BEST_COMPRESSION:9,Z_DEFAULT_COMPRESSION:-1,Z_FILTERED:1,Z_HUFFMAN_ONLY:2,Z_RLE:3,Z_FIXED:4,Z_DEFAULT_STRATEGY:0,Z_BINARY:0,Z_TEXT:1,Z_UNKNOWN:2,Z_DEFLATED:8}),_d}var Rd,H2;function ER(){if(H2)return Rd;H2=1;function t(){this.text=0,this.time=0,this.xflags=0,this.os=0,this.extra=null,this.extra_len=0,this.name="",this.comment="",this.hcrc=0,this.done=!1}return Rd=t,Rd}var V2;function SR(){if(V2)return Co;V2=1;var 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this.onEnd(v),this.ended=!0,!1;h.next_out&&(h.avail_out===0||v===r.Z_STREAM_END||h.avail_in===0&&(b===r.Z_FINISH||b===r.Z_SYNC_FLUSH))&&(this.options.to==="string"?(A=n.utf8border(h.output,h.next_out),S=h.next_out-A,E=n.buf2string(h.output,A),h.next_out=S,h.avail_out=p-S,S&&e.arraySet(h.output,h.output,A,S,0),this.onData(E)):this.onData(e.shrinkBuf(h.output,h.next_out))),h.avail_in===0&&h.avail_out===0&&(I=!0)}while((h.avail_in>0||h.avail_out===0)&&v!==r.Z_STREAM_END);return v===r.Z_STREAM_END&&(b=r.Z_FINISH),b===r.Z_FINISH?(v=t.inflateEnd(this.strm),this.onEnd(v),this.ended=!0,v===r.Z_OK):(b===r.Z_SYNC_FLUSH&&(this.onEnd(r.Z_OK),h.avail_out=0),!0)},c.prototype.onData=function(f){this.chunks.push(f)},c.prototype.onEnd=function(f){f===r.Z_OK&&(this.options.to==="string"?this.result=this.chunks.join(""):this.result=e.flattenChunks(this.chunks)),this.chunks=[],this.err=f,this.msg=this.strm.msg};function l(f,d){var h=new c(d);if(h.push(f,!0),h.err)throw h.msg||o[h.err];return h.result}function u(f,d){return d=d||{},d.raw=!0,l(f,d)}return Co.Inflate=c,Co.inflate=l,Co.inflateRaw=u,Co.ungzip=l,Co}var Fd,j2;function CR(){if(j2)return Fd;j2=1;var t=Nr().assign,e=wR(),n=SR(),r=G2(),o={};return t(o,e,n,r),Fd=o,Fd}var Jl=CR();async function zr(t){try{let e,n=0,r=0;const o=[];let i=0,s;do{const c=t.subarray(n);if(s=new Jl.Inflate,{strm:e}=s,s.push(c,Jl.Z_SYNC_FLUSH),s.err)throw new Error(s.msg);n+=e.next_in,o[r]=s.result,i+=o[r].length,r+=1}while(e.avail_in);const a=new Uint8Array(i);for(let c=0,l=0;c<o.length;c++)a.set(o[c],l),l+=o[c].length;return Ke.Buffer.from(a)}catch(e){throw/incorrect header check/.exec(`${e}`)?new Error("problem decompressing block: incorrect gzip header check"):e}}async function q2(t,e){try{let n;const{minv:r,maxv:o}=e;let i=r.blockPosition,s=r.dataPosition;const a=[],c=[],l=[];let u=0,f=0;do{const p=t.subarray(i-r.blockPosition),y=new Jl.Inflate;if({strm:n}=y,y.push(p,Jl.Z_SYNC_FLUSH),y.err)throw new Error(y.msg);const v=y.result;a.push(v);let b=v.length;c.push(i),l.push(s),a.length===1&&r.dataPosition&&(a[0]=a[0].subarray(r.dataPosition),b=a[0].length);const A=i;if(i+=n.next_in,s+=b,A>=o.blockPosition){a[f]=a[f].subarray(0,o.blockPosition===r.blockPosition?o.dataPosition-r.dataPosition+1:o.dataPosition+1),c.push(i),l.push(s),u+=a[f].length;break}u+=a[f].length,f++}while(n.avail_in);const d=new Uint8Array(u);for(let p=0,y=0;p<a.length;p++)d.set(a[p],y),y+=a[p].length;return{buffer:Ke.Buffer.from(d),cpositions:c,dpositions:l}}catch(n){throw/incorrect header check/.exec(`${n}`)?new Error("problem decompressing block: incorrect gzip header check"):n}}var Md,W2;function IR(){if(W2)return Md;W2=1,Md=e;var t=null;try{t=new WebAssembly.Instance(new WebAssembly.Module(new Uint8Array([0,97,115,109,1,0,0,0,1,13,2,96,0,1,127,96,4,127,127,127,127,1,127,3,7,6,0,1,1,1,1,1,6,6,1,127,1,65,0,11,7,50,6,3,109,117,108,0,1,5,100,105,118,95,115,0,2,5,100,105,118,95,117,0,3,5,114,101,109,95,115,0,4,5,114,101,109,95,117,0,5,8,103,101,116,95,104,105,103,104,0,0,10,191,1,6,4,0,35,0,11,36,1,1,126,32,0,173,32,1,173,66,32,134,132,32,2,173,32,3,173,66,32,134,132,126,34,4,66,32,135,167,36,0,32,4,167,11,36,1,1,126,32,0,173,32,1,173,66,32,134,132,32,2,173,32,3,173,66,32,134,132,127,34,4,66,32,135,167,36,0,32,4,167,11,36,1,1,126,32,0,173,32,1,173,66,32,134,132,32,2,173,32,3,173,66,32,134,132,128,34,4,66,32,135,167,36,0,32,4,167,11,36,1,1,126,32,0,173,32,1,173,66,32,134,132,32,2,173,32,3,173,66,32,134,132,129,34,4,66,32,135,167,36,0,32,4,167,11,36,1,1,126,32,0,173,32,1,173,66,32,134,132,32,2,173,32,3,173,66,32,134,132,130,34,4,66,32,135,167,36,0,32,4,167,11])),{}).exports}catch{}function 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oe=s(c(Y,8)),se=b,ae=0;ae<M.length;ae+=8){var ce=Math.min(8,M.length-ae),ye=parseInt(M.substring(ae,ae+ce),Y);if(ce<8){var de=s(c(Y,ce));se=se.mul(de).add(s(ye))}else se=se.mul(oe),se=se.add(s(ye))}return se.unsigned=C,se}e.fromString=l;function u(M,C){return typeof M=="number"?s(M,C):typeof M=="string"?l(M,C):a(M.low,M.high,typeof C=="boolean"?C:M.unsigned)}e.fromValue=u;var f=65536,d=1<<24,h=f*f,p=h*h,y=p/2,v=i(d),b=i(0);e.ZERO=b;var A=i(0,!0);e.UZERO=A;var S=i(1);e.ONE=S;var E=i(1,!0);e.UONE=E;var I=i(-1);e.NEG_ONE=I;var _=a(-1,2147483647,!1);e.MAX_VALUE=_;var B=a(-1,-1,!0);e.MAX_UNSIGNED_VALUE=B;var N=a(0,-2147483648,!1);e.MIN_VALUE=N;var F=e.prototype;return F.toInt=function(){return this.unsigned?this.low>>>0:this.low},F.toNumber=function(){return this.unsigned?(this.high>>>0)*h+(this.low>>>0):this.high*h+(this.low>>>0)},F.toString=function(C){if(C=C||10,C<2||36<C)throw RangeError("radix");if(this.isZero())return"0";if(this.isNegative())if(this.eq(N)){var Y=s(C),Q=this.div(Y),oe=Q.mul(Y).sub(this);return Q.toString(C)+oe.toInt().toString(C)}else return"-"+this.neg().toString(C);for(var se=s(c(C,6),this.unsigned),ae=this,ce="";;){var ye=ae.div(se),de=ae.sub(ye.mul(se)).toInt()>>>0,Ce=de.toString(C);if(ae=ye,ae.isZero())return Ce+ce;for(;Ce.length<6;)Ce="0"+Ce;ce=""+Ce+ce}},F.getHighBits=function(){return this.high},F.getHighBitsUnsigned=function(){return this.high>>>0},F.getLowBits=function(){return this.low},F.getLowBitsUnsigned=function(){return this.low>>>0},F.getNumBitsAbs=function(){if(this.isNegative())return this.eq(N)?64:this.neg().getNumBitsAbs();for(var C=this.high!=0?this.high:this.low,Y=31;Y>0&&!(C&1<<Y);Y--);return this.high!=0?Y+33:Y+1},F.isZero=function(){return this.high===0&&this.low===0},F.eqz=F.isZero,F.isNegative=function(){return!this.unsigned&&this.high<0},F.isPositive=function(){return this.unsigned||this.high>=0},F.isOdd=function(){return(this.low&1)===1},F.isEven=function(){return(this.low&1)===0},F.equals=function(C){return n(C)||(C=u(C)),this.unsigned!==C.unsigned&&this.high>>>31===1&&C.high>>>31===1?!1:this.high===C.high&&this.low===C.low},F.eq=F.equals,F.notEquals=function(C){return!this.eq(C)},F.neq=F.notEquals,F.ne=F.notEquals,F.lessThan=function(C){return this.comp(C)<0},F.lt=F.lessThan,F.lessThanOrEqual=function(C){return this.comp(C)<=0},F.lte=F.lessThanOrEqual,F.le=F.lessThanOrEqual,F.greaterThan=function(C){return this.comp(C)>0},F.gt=F.greaterThan,F.greaterThanOrEqual=function(C){return this.comp(C)>=0},F.gte=F.greaterThanOrEqual,F.ge=F.greaterThanOrEqual,F.compare=function(C){if(n(C)||(C=u(C)),this.eq(C))return 0;var Y=this.isNegative(),Q=C.isNegative();return Y&&!Q?-1:!Y&&Q?1:this.unsigned?C.high>>>0>this.high>>>0||C.high===this.high&&C.low>>>0>this.low>>>0?-1:1:this.sub(C).isNegative()?-1:1},F.comp=F.compare,F.negate=function(){return!this.unsigned&&this.eq(N)?N:this.not().add(S)},F.neg=F.negate,F.add=function(C){n(C)||(C=u(C));var Y=this.high>>>16,Q=this.high&65535,oe=this.low>>>16,se=this.low&65535,ae=C.high>>>16,ce=C.high&65535,ye=C.low>>>16,de=C.low&65535,Ce=0,me=0,Ee=0,De=0;return De+=se+de,Ee+=De>>>16,De&=65535,Ee+=oe+ye,me+=Ee>>>16,Ee&=65535,me+=Q+ce,Ce+=me>>>16,me&=65535,Ce+=Y+ae,Ce&=65535,a(Ee<<16|De,Ce<<16|me,this.unsigned)},F.subtract=function(C){return n(C)||(C=u(C)),this.add(C.neg())},F.sub=F.subtract,F.multiply=function(C){if(this.isZero())return b;if(n(C)||(C=u(C)),t){var Y=t.mul(this.low,this.high,C.low,C.high);return a(Y,t.get_high(),this.unsigned)}if(C.isZero())return b;if(this.eq(N))return C.isOdd()?N:b;if(C.eq(N))return this.isOdd()?N:b;if(this.isNegative())return C.isNegative()?this.neg().mul(C.neg()):this.neg().mul(C).neg();if(C.isNegative())return this.mul(C.neg()).neg();if(this.lt(v)&&C.lt(v))return s(this.toNumber()*C.toNumber(),this.unsigned);var Q=this.high>>>16,oe=this.high&65535,se=this.low>>>16,ae=this.low&65535,ce=C.high>>>16,ye=C.high&65535,de=C.low>>>16,Ce=C.low&65535,me=0,Ee=0,De=0,Ge=0;return Ge+=ae*Ce,De+=Ge>>>16,Ge&=65535,De+=se*Ce,Ee+=De>>>16,De&=65535,De+=ae*de,Ee+=De>>>16,De&=65535,Ee+=oe*Ce,me+=Ee>>>16,Ee&=65535,Ee+=se*de,me+=Ee>>>16,Ee&=65535,Ee+=ae*ye,me+=Ee>>>16,Ee&=65535,me+=Q*Ce+oe*de+se*ye+ae*ce,me&=65535,a(De<<16|Ge,me<<16|Ee,this.unsigned)},F.mul=F.multiply,F.divide=function(C){if(n(C)||(C=u(C)),C.isZero())throw Error("division by zero");if(t){if(!this.unsigned&&this.high===-2147483648&&C.low===-1&&C.high===-1)return this;var Y=(this.unsigned?t.div_u:t.div_s)(this.low,this.high,C.low,C.high);return a(Y,t.get_high(),this.unsigned)}if(this.isZero())return this.unsigned?A:b;var Q,oe,se;if(this.unsigned){if(C.unsigned||(C=C.toUnsigned()),C.gt(this))return A;if(C.gt(this.shru(1)))return E;se=A}else{if(this.eq(N)){if(C.eq(S)||C.eq(I))return N;if(C.eq(N))return S;var ae=this.shr(1);return Q=ae.div(C).shl(1),Q.eq(b)?C.isNegative()?S:I:(oe=this.sub(C.mul(Q)),se=Q.add(oe.div(C)),se)}else if(C.eq(N))return this.unsigned?A:b;if(this.isNegative())return C.isNegative()?this.neg().div(C.neg()):this.neg().div(C).neg();if(C.isNegative())return this.div(C.neg()).neg();se=b}for(oe=this;oe.gte(C);){Q=Math.max(1,Math.floor(oe.toNumber()/C.toNumber()));for(var ce=Math.ceil(Math.log(Q)/Math.LN2),ye=ce<=48?1:c(2,ce-48),de=s(Q),Ce=de.mul(C);Ce.isNegative()||Ce.gt(oe);)Q-=ye,de=s(Q,this.unsigned),Ce=de.mul(C);de.isZero()&&(de=S),se=se.add(de),oe=oe.sub(Ce)}return se},F.div=F.divide,F.modulo=function(C){if(n(C)||(C=u(C)),t){var Y=(this.unsigned?t.rem_u:t.rem_s)(this.low,this.high,C.low,C.high);return a(Y,t.get_high(),this.unsigned)}return this.sub(this.div(C).mul(C))},F.mod=F.modulo,F.rem=F.modulo,F.not=function(){return a(~this.low,~this.high,this.unsigned)},F.and=function(C){return n(C)||(C=u(C)),a(this.low&C.low,this.high&C.high,this.unsigned)},F.or=function(C){return n(C)||(C=u(C)),a(this.low|C.low,this.high|C.high,this.unsigned)},F.xor=function(C){return n(C)||(C=u(C)),a(this.low^C.low,this.high^C.high,this.unsigned)},F.shiftLeft=function(C){return n(C)&&(C=C.toInt()),(C&=63)===0?this:C<32?a(this.low<<C,this.high<<C|this.low>>>32-C,this.unsigned):a(0,this.low<<C-32,this.unsigned)},F.shl=F.shiftLeft,F.shiftRight=function(C){return n(C)&&(C=C.toInt()),(C&=63)===0?this:C<32?a(this.low>>>C|this.high<<32-C,this.high>>C,this.unsigned):a(this.high>>C-32,this.high>=0?0:-1,this.unsigned)},F.shr=F.shiftRight,F.shiftRightUnsigned=function(C){if(n(C)&&(C=C.toInt()),C&=63,C===0)return this;var Y=this.high;if(C<32){var Q=this.low;return a(Q>>>C|Y<<32-C,Y>>>C,this.unsigned)}else return C===32?a(Y,0,this.unsigned):a(Y>>>C-32,0,this.unsigned)},F.shru=F.shiftRightUnsigned,F.shr_u=F.shiftRightUnsigned,F.toSigned=function(){return this.unsigned?a(this.low,this.high,!1):this},F.toUnsigned=function(){return this.unsigned?this:a(this.low,this.high,!0)},F.toBytes=function(C){return C?this.toBytesLE():this.toBytesBE()},F.toBytesLE=function(){var C=this.high,Y=this.low;return[Y&255,Y>>>8&255,Y>>>16&255,Y>>>24,C&255,C>>>8&255,C>>>16&255,C>>>24]},F.toBytesBE=function(){var C=this.high,Y=this.low;return[C>>>24,C>>>16&255,C>>>8&255,C&255,Y>>>24,Y>>>16&255,Y>>>8&255,Y&255]},e.fromBytes=function(C,Y,Q){return Q?e.fromBytesLE(C,Y):e.fromBytesBE(C,Y)},e.fromBytesLE=function(C,Y){return new e(C[0]|C[1]<<8|C[2]<<16|C[3]<<24,C[4]|C[5]<<8|C[6]<<16|C[7]<<24,Y)},e.fromBytesBE=function(C,Y){return new e(C[4]<<24|C[5]<<16|C[6]<<8|C[7],C[0]<<24|C[1]<<16|C[2]<<8|C[3],Y)},Md}var TR=IR();const $l=Xl(TR),eu=1;class DR{constructor({filehandle:e,path:n}){if(e)this.filehandle=e;else if(n)this.filehandle=new Ct(n);else throw new TypeError("either filehandle or path must be defined")}_readLongWithOverflow(e,n=0,r=!0){const o=$l.fromBytesLE(e.slice(n,n+8),r);if(o.greaterThan(Number.MAX_SAFE_INTEGER)||o.lessThan(Number.MIN_SAFE_INTEGER))throw new TypeError("integer overflow");return o.toNumber()}_getIndex(){return this.index||(this.index=this._readIndex()),this.index}async _readIndex(){let e=Ke.Buffer.allocUnsafe(8);await this.filehandle.read(e,0,8,0);const n=this._readLongWithOverflow(e,0,!0);if(!n)return[[0,0]];const r=new Array(n+1);r[0]=[0,0];const o=8*2*n;if(o>Number.MAX_SAFE_INTEGER)throw new TypeError("integer overflow");e=Ke.Buffer.allocUnsafe(o),await this.filehandle.read(e,0,o,8);for(let i=0;i<n;i+=1){const s=this._readLongWithOverflow(e,i*16),a=this._readLongWithOverflow(e,i*16+8);r[i+1]=[s,a]}return r}async getLastBlock(){const e=await this._getIndex();if(e.length)return e[e.length-1]}async getRelevantBlocksForRead(e,n){const r=n+e;if(e===0)return[];const o=await this._getIndex(),i=[],s=(d,h)=>{const p=d[eu],y=h?h[eu]:1/0;return p<=n&&y>n?0:p<n?-1:1};let a=0,c=o.length-1,l=Math.floor(o.length/2),u=s(o[l],o[l+1]);for(;u!==0;)u>0?c=l-1:u<0&&(a=l+1),l=Math.ceil((c-a)/2)+a,u=s(o[l],o[l+1]);i.push(o[l]);let f=l+1;for(;f<o.length&&(i.push(o[f]),!(o[f][eu]>=r));f+=1);return i[i.length-1][eu]<r&&i.push([]),i}}class Y2{constructor({filehandle:e,path:n,gziFilehandle:r,gziPath:o}){if(e)this.filehandle=e;else if(n)this.filehandle=new Ct(n);else throw new TypeError("either filehandle or path must be defined");if(!r&&!o&&!n)throw new TypeError("either gziFilehandle or gziPath must be defined");this.gzi=new DR({filehandle:r,path:!r&&!o&&n?o:`${n}.gzi`})}async stat(){const e=await this.filehandle.stat();return Object.assign(e,{size:await this.getUncompressedFileSize(),blocks:void 0,blksize:void 0})}async getUncompressedFileSize(){const[,e]=await this.gzi.getLastBlock(),{size:n}=await this.filehandle.stat(),r=Ke.Buffer.allocUnsafe(4),{bytesRead:o}=await this.filehandle.read(r,0,4,n-28-4);if(o!==4)throw new Error("read error");const i=r.readUInt32LE(0);return e+i}async _readAndUncompressBlock(e,[n],[r]){let o=r;o||(o=(await this.filehandle.stat()).size);const i=o-n;return await this.filehandle.read(e,0,i,n),await zr(e.slice(0,i))}async read(e,n,r,o){const i=await this.gzi.getRelevantBlocksForRead(r,o),s=Ke.Buffer.allocUnsafe(32768*2);let a=n,c=0;for(let l=0;l<i.length-1;l+=1){const u=await this._readAndUncompressBlock(s,i[l],i[l+1]),[,f]=i[l],d=f>=o?0:o-f,h=Math.min(o+r,f+u.length)-f;d>=0&&d<u.length&&(u.copy(e,a,d,h),a+=h-d,c+=h-d)}return{bytesRead:c,buffer:e}}}function Q2(t,e){return t.offset+t.lineBytes*Math.floor(e/t.lineLength)+e%t.lineLength}async function BR(t,e){const n=await t.readFile(e);if(!(n!=null&&n.length))throw new Error("No data read from FASTA index (FAI) file");let r=0,o;const i=n.toString("utf8").split(/\r?\n/).filter(s=>/\S/.test(s)).map(s=>s.split("	")).filter(s=>s[0]!=="").map(s=>((!o||o.name!==s[0])&&(o={name:s[0],id:r},r+=1),{id:o.id,name:s[0],length:+s[1],start:0,end:+s[1],offset:+s[2],lineLength:+s[3],lineBytes:+s[4]}));return{name:Object.fromEntries(i.map(s=>[s.name,s])),id:Object.fromEntries(i.map(s=>[s.id,s]))}}class Z2{constructor({fasta:e,fai:n,path:r,faiPath:o}){if(e)this.fasta=e;else if(r)this.fasta=new Ct(r);else throw new Error("Need to pass filehandle for fasta or path to localfile");if(n)this.fai=n;else if(o)this.fai=new Ct(o);else if(r)this.fai=new Ct(`${r}.fai`);else throw new Error("Need to pass filehandle for  or path to localfile")}async _getIndexes(e){return this.indexes||(this.indexes=BR(this.fai,e)),this.indexes}async getSequenceNames(e){return Object.keys((await this._getIndexes(e)).name)}async getSequenceSizes(e){const n={},r=await this._getIndexes(e);for(const o of Object.values(r.id))n[o.name]=o.length;return n}async getSequenceSize(e,n){var r;return(r=(await this._getIndexes(n)).name[e])===null||r===void 0?void 0:r.length}async hasReferenceSequence(e,n){return!!(await this._getIndexes(n)).name[e]}async getResiduesById(e,n,r,o){const i=(await this._getIndexes(o)).id[e];if(i)return this._fetchFromIndexEntry(i,n,r,o)}async getResiduesByName(e,n,r,o){const i=(await this._getIndexes(o)).name[e];if(i)return this._fetchFromIndexEntry(i,n,r,o)}async getSequence(e,n,r,o){return this.getResiduesByName(e,n,r,o)}async _fetchFromIndexEntry(e,n=0,r,o){let i=r;if(n<0)throw new TypeError("regionStart cannot be less than 0");if((i===void 0||i>e.length)&&(i=e.length),n>=i)return"";const s=Q2(e,n),a=Q2(e,i)-s,c=Ke.Buffer.allocUnsafe(a);return await this.fasta.read(c,0,a,s,o),c.toString("utf8").replace(/\s+/g,"")}}class kR extends Z2{constructor({fasta:e,path:n,fai:r,faiPath:o,gzi:i,gziPath:s}){super({fasta:e,path:n,fai:r,faiPath:o}),e&&i?this.fasta=new Y2({filehandle:e,gziFilehandle:i}):n&&s&&(this.fasta=new Y2({path:n,gziPath:s}))}}function X2(t){return t.split(">").filter(e=>/\S/.test(e)).map(e=>{const[n,...r]=e.split(`
-`),[o,...i]=n.split(" "),s=r.join("").replace(/\s/g,"");return{id:o,description:i.join(" "),sequence:s}})}class _R{constructor({fasta:e,path:n}){if(e)this.fasta=e;else if(n)this.fasta=new Ct(n);else throw new Error("Need to pass fasta or path");this.data=this.fasta.readFile().then(r=>{const o=r.toString("utf8");return X2(o)})}async fetch(e,n,r){const i=(await this.data).find(a=>a.id===e),s=r-n;if(!i)throw new Error(`no sequence with id ${e} exists`);return i.sequence.slice(n,s)}async getSequenceNames(){return(await this.data).map(n=>n.id)}}const RR=Object.freeze(Object.defineProperty({__proto__:null,BgzipIndexedFasta:kR,FetchableSmallFasta:_R,IndexedFasta:Z2,parseSmallFasta:X2},Symbol.toStringTag,{value:"Module"})),K2=BigInt(32);function FR(t,e,n){const r=+!!n,o=+!n;return BigInt(t.getInt32(e,n)*o+t.getInt32(e+4,n)*r)<<K2|BigInt(t.getUint32(e,n)*r+t.getUint32(e+4,n)*o)}function MR(t,e,n){const r=t.getUint32(e,n),o=t.getUint32(e+4,n),i=+!!n,s=+!n;return BigInt(r*s+o*i)<<K2|BigInt(r*i+o*s)}"getBigInt64"in DataView||(DataView.prototype.getBigInt64=function(t,e){return FR(this,t,e)}),"getBigUint64"in DataView||(DataView.prototype.getBigUint64=function(t,e){return MR(this,t,e)});class PR{}class LR{constructor(){this.signals=new Set,this.abortController=new AbortController}addSignal(e=new PR){if(this.signal.aborted)throw new Error("cannot add a signal, already aborted!");this.signals.add(e),e.aborted?this.handleAborted(e):typeof e.addEventListener=="function"&&e.addEventListener("abort",()=>{this.handleAborted(e)})}handleAborted(e){this.signals.delete(e),this.signals.size===0&&this.abortController.abort()}get signal(){return this.abortController.signal}abort(){this.abortController.abort()}}class OR{constructor(){this.callbacks=new Set}addCallback(e=()=>{}){this.callbacks.add(e),e(this.currentMessage)}callback(e){this.currentMessage=e;for(const n of this.callbacks)n(e)}}class Di{constructor({fill:e,cache:n}){if(typeof e!="function")throw new TypeError("must pass a fill function");if(typeof n!="object")throw new TypeError("must pass a cache object");if(typeof n.get!="function"||typeof n.set!="function"||typeof n.delete!="function")throw new TypeError("cache must implement get(key), set(key, val), and and delete(key)");this.cache=n,this.fillCallback=e}static isAbortException(e){return e.name==="AbortError"||e.code==="ERR_ABORTED"||e.message==="AbortError: aborted"||e.message==="Error: aborted"}evict(e,n){this.cache.get(e)===n&&this.cache.delete(e)}fill(e,n,r,o){const i=new LR,s=new OR;s.addCallback(o);const a={aborter:i,promise:this.fillCallback(n,i.signal,c=>{s.callback(c)}),settled:!1,statusReporter:s,get aborted(){return this.aborter.signal.aborted}};a.aborter.addSignal(r),a.aborter.signal.addEventListener("abort",()=>{a.settled||this.evict(e,a)}),a.promise.then(()=>{a.settled=!0},()=>{a.settled=!0,this.evict(e,a)}).catch(c=>{throw console.error(c),c}),this.cache.set(e,a)}static checkSinglePromise(e,n){function r(){if(n!=null&&n.aborted)throw Object.assign(new Error("aborted"),{code:"ERR_ABORTED"})}return e.then(o=>(r(),o),o=>{throw r(),o})}has(e){return this.cache.has(e)}get(e,n,r,o){if(!r&&n instanceof AbortSignal)throw new TypeError("second get argument appears to be an AbortSignal, perhaps you meant to pass `null` for the fill data?");const i=this.cache.get(e);return i?i.aborted&&!i.settled?(this.evict(e,i),this.get(e,n,r,o)):i.settled?i.promise:(i.aborter.addSignal(r),i.statusReporter.addCallback(o),Di.checkSinglePromise(i.promise,r)):(this.fill(e,n,r,o),Di.checkSinglePromise(this.cache.get(e).promise,r))}delete(e){const n=this.cache.get(e);n&&(n.settled||n.aborter.abort(),this.cache.delete(e))}clear(){const e=this.cache.keys();let n=0;for(let r=e.next();!r.done;r=e.next())this.delete(r.value),n+=1;return n}}var Pd,J2;function NR(){if(J2)return Pd;J2=1;class t{constructor(n={}){if(!(n.maxSize&&n.maxSize>0))throw new TypeError("`maxSize` must be a number greater than 0");this.maxSize=n.maxSize,this.cache=new Map,this.oldCache=new Map,this._size=0}_set(n,r){this.cache.set(n,r),this._size++,this._size>=this.maxSize&&(this._size=0,this.oldCache=this.cache,this.cache=new Map)}get(n){if(this.cache.has(n))return this.cache.get(n);if(this.oldCache.has(n)){const r=this.oldCache.get(n);return this.oldCache.delete(n),this._set(n,r),r}}set(n,r){return this.cache.has(n)?this.cache.set(n,r):this._set(n,r),this}has(n){return this.cache.has(n)||this.oldCache.has(n)}peek(n){if(this.cache.has(n))return this.cache.get(n);if(this.oldCache.has(n))return this.oldCache.get(n)}delete(n){const r=this.cache.delete(n);return r&&this._size--,this.oldCache.delete(n)||r}clear(){this.cache.clear(),this.oldCache.clear(),this._size=0}*keys(){for(const[n]of this)yield n}*values(){for(const[,n]of this)yield n}*[Symbol.iterator](){for(const n of this.cache)yield n;for(const n of this.oldCache){const[r]=n;this.cache.has(r)||(yield n)}}get size(){let n=0;for(const r of 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e;a--,l+=r[i++]<<u,u+=8}n.head&&(n.head.time=l),n.flags&512&&n.wrap&4&&(F[0]=l&255,F[1]=l>>>8&255,F[2]=l>>>16&255,F[3]=l>>>24&255,n.check=jn(n.check,F,4,0)),l=0,u=0,n.mode=mw;case mw:for(;u<16;){if(a===0)break e;a--,l+=r[i++]<<u,u+=8}n.head&&(n.head.xflags=l&255,n.head.os=l>>8),n.flags&512&&n.wrap&4&&(F[0]=l&255,F[1]=l>>>8&255,n.check=jn(n.check,F,2,0)),l=0,u=0,n.mode=yw;case yw:if(n.flags&1024){for(;u<16;){if(a===0)break e;a--,l+=r[i++]<<u,u+=8}n.length=l,n.head&&(n.head.extra_len=l),n.flags&512&&n.wrap&4&&(F[0]=l&255,F[1]=l>>>8&255,n.check=jn(n.check,F,2,0)),l=0,u=0}else n.head&&(n.head.extra=null);n.mode=bw;case bw:if(n.flags&1024&&(h=n.length,h>a&&(h=a),h&&(n.head&&(B=n.head.extra_len-n.length,n.head.extra||(n.head.extra=new Uint8Array(n.head.extra_len)),n.head.extra.set(r.subarray(i,i+h),B)),n.flags&512&&n.wrap&4&&(n.check=jn(n.check,r,h,i)),a-=h,i+=h,n.length-=h),n.length))break e;n.length=0,n.mode=ww;case ww:if(n.flags&2048){if(a===0)break e;h=0;do 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Ud:if(n.last){l>>>=u&7,u-=u&7,n.mode=Hd;break}for(;u<3;){if(a===0)break e;a--,l+=r[i++]<<u,u+=8}switch(n.last=l&1,l>>>=1,u-=1,l&3){case 0:n.mode=Ew;break;case 1:if(EF(n),n.mode=su,e===ru){l>>>=2,u-=2;break e}break;case 2:n.mode=Cw;break;case 3:t.msg="invalid block type",n.mode=ct}l>>>=2,u-=2;break;case Ew:for(l>>>=u&7,u-=u&7;u<32;){if(a===0)break e;a--,l+=r[i++]<<u,u+=8}if((l&65535)!==(l>>>16^65535)){t.msg="invalid stored block lengths",n.mode=ct;break}if(n.length=l&65535,l=0,u=0,n.mode=Gd,e===ru)break e;case Gd:n.mode=Sw;case Sw:if(h=n.length,h){if(h>a&&(h=a),h>c&&(h=c),h===0)break e;o.set(r.subarray(i,i+h),s),a-=h,i+=h,c-=h,s+=h,n.length-=h;break}n.mode=rr;break;case Cw:for(;u<14;){if(a===0)break e;a--,l+=r[i++]<<u,u+=8}if(n.nlen=(l&31)+257,l>>>=5,u-=5,n.ndist=(l&31)+1,l>>>=5,u-=5,n.ncode=(l&15)+4,l>>>=4,u-=4,n.nlen>286||n.ndist>30){t.msg="too many length or distance symbols",n.mode=ct;break}n.have=0,n.mode=Iw;case Iw:for(;n.have<n.ncode;){for(;u<3;){if(a===0)break e;a--,l+=r[i++]<<u,u+=8}n.lens[Y[n.have++]]=l&7,l>>>=3,u-=3}for(;n.have<19;)n.lens[Y[n.have++]]=0;if(n.lencode=n.lendyn,n.lenbits=7,M={bits:n.lenbits},N=Fa(dF,n.lens,0,19,n.lencode,0,n.work,M),n.lenbits=M.bits,N){t.msg="invalid code lengths set",n.mode=ct;break}n.have=0,n.mode=Tw;case Tw:for(;n.have<n.nlen+n.ndist;){for(;v=n.lencode[l&(1<<n.lenbits)-1],b=v>>>24,A=v>>>16&255,S=v&65535,!(b<=u);){if(a===0)break e;a--,l+=r[i++]<<u,u+=8}if(S<16)l>>>=b,u-=b,n.lens[n.have++]=S;else{if(S===16){for(C=b+2;u<C;){if(a===0)break e;a--,l+=r[i++]<<u,u+=8}if(l>>>=b,u-=b,n.have===0){t.msg="invalid bit length repeat",n.mode=ct;break}B=n.lens[n.have-1],h=3+(l&3),l>>>=2,u-=2}else if(S===17){for(C=b+3;u<C;){if(a===0)break e;a--,l+=r[i++]<<u,u+=8}l>>>=b,u-=b,B=0,h=3+(l&7),l>>>=3,u-=3}else{for(C=b+7;u<C;){if(a===0)break e;a--,l+=r[i++]<<u,u+=8}l>>>=b,u-=b,B=0,h=11+(l&127),l>>>=7,u-=7}if(n.have+h>n.nlen+n.ndist){t.msg="invalid bit length repeat",n.mode=ct;break}for(;h--;)n.lens[n.have++]=B}}if(n.mode===ct)break;if(n.lens[256]===0){t.msg="invalid code -- missing end-of-block",n.mode=ct;break}if(n.lenbits=9,M={bits:n.lenbits},N=Fa(cw,n.lens,0,n.nlen,n.lencode,0,n.work,M),n.lenbits=M.bits,N){t.msg="invalid literal/lengths set",n.mode=ct;break}if(n.distbits=6,n.distcode=n.distdyn,M={bits:n.distbits},N=Fa(lw,n.lens,n.nlen,n.ndist,n.distcode,0,n.work,M),n.distbits=M.bits,N){t.msg="invalid distances set",n.mode=ct;break}if(n.mode=su,e===ru)break e;case su:n.mode=au;case au:if(a>=6&&c>=258){t.next_out=s,t.avail_out=c,t.next_in=i,t.avail_in=a,n.hold=l,n.bits=u,cF(t,d),s=t.next_out,o=t.output,c=t.avail_out,i=t.next_in,r=t.input,a=t.avail_in,l=n.hold,u=n.bits,n.mode===rr&&(n.back=-1);break}for(n.back=0;v=n.lencode[l&(1<<n.lenbits)-1],b=v>>>24,A=v>>>16&255,S=v&65535,!(b<=u);){if(a===0)break e;a--,l+=r[i++]<<u,u+=8}if(A&&!(A&240)){for(E=b,I=A,_=S;v=n.lencode[_+((l&(1<<E+I)-1)>>E)],b=v>>>24,A=v>>>16&255,S=v&65535,!(E+b<=u);){if(a===0)break e;a--,l+=r[i++]<<u,u+=8}l>>>=E,u-=E,n.back+=E}if(l>>>=b,u-=b,n.back+=b,n.length=S,A===0){n.mode=Rw;break}if(A&32){n.back=-1,n.mode=rr;break}if(A&64){t.msg="invalid literal/length code",n.mode=ct;break}n.extra=A&15,n.mode=Dw;case Dw:if(n.extra){for(C=n.extra;u<C;){if(a===0)break e;a--,l+=r[i++]<<u,u+=8}n.length+=l&(1<<n.extra)-1,l>>>=n.extra,u-=n.extra,n.back+=n.extra}n.was=n.length,n.mode=Bw;case Bw:for(;v=n.distcode[l&(1<<n.distbits)-1],b=v>>>24,A=v>>>16&255,S=v&65535,!(b<=u);){if(a===0)break e;a--,l+=r[i++]<<u,u+=8}if(!(A&240)){for(E=b,I=A,_=S;v=n.distcode[_+((l&(1<<E+I)-1)>>E)],b=v>>>24,A=v>>>16&255,S=v&65535,!(E+b<=u);){if(a===0)break e;a--,l+=r[i++]<<u,u+=8}l>>>=E,u-=E,n.back+=E}if(l>>>=b,u-=b,n.back+=b,A&64){t.msg="invalid distance code",n.mode=ct;break}n.offset=S,n.extra=A&15,n.mode=kw;case kw:if(n.extra){for(C=n.extra;u<C;){if(a===0)break e;a--,l+=r[i++]<<u,u+=8}n.offset+=l&(1<<n.extra)-1,l>>>=n.extra,u-=n.extra,n.back+=n.extra}if(n.offset>n.dmax){t.msg="invalid distance too far back",n.mode=ct;break}n.mode=_w;case _w:if(c===0)break e;if(h=d-c,n.offset>h){if(h=n.offset-h,h>n.whave&&n.sane){t.msg="invalid distance too far back",n.mode=ct;break}h>n.wnext?(h-=n.wnext,p=n.wsize-h):p=n.wnext-h,h>n.length&&(h=n.length),y=n.window}else y=o,p=s-n.offset,h=n.length;h>c&&(h=c),c-=h,n.length-=h;do o[s++]=y[p++];while(--h);n.length===0&&(n.mode=au);break;case Rw:if(c===0)break e;o[s++]=n.length,c--,n.mode=au;break;case Hd:if(n.wrap){for(;u<32;){if(a===0)break e;a--,l|=r[i++]<<u,u+=8}if(d-=c,t.total_out+=d,n.total+=d,n.wrap&4&&d&&(t.adler=n.check=n.flags?jn(n.check,o,d,s-d):Ld(n.check,o,d,s-d)),d=c,n.wrap&4&&(n.flags?l:Ow(l))!==n.check){t.msg="incorrect data check",n.mode=ct;break}l=0,u=0}n.mode=Fw;case Fw:if(n.wrap&&n.flags){for(;u<32;){if(a===0)break e;a--,l+=r[i++]<<u,u+=8}if(n.wrap&4&&l!==(n.total&4294967295)){t.msg="incorrect length check",n.mode=ct;break}l=0,u=0}n.mode=Mw;case Mw:N=gF;break e;case ct:N=fw;break e;case Pw:return hw;case Lw:default:return hn}return t.next_out=s,t.avail_out=c,t.next_in=i,t.avail_in=a,n.hold=l,n.bits=u,(n.wsize||d!==t.avail_out&&n.mode<ct&&(n.mode<Hd||e!==uw))&&Vw(t,t.output,t.next_out,d-t.avail_out),f-=t.avail_in,d-=t.avail_out,t.total_in+=f,t.total_out+=d,n.total+=d,n.wrap&4&&d&&(t.adler=n.check=n.flags?jn(n.check,o,d,t.next_out-d):Ld(n.check,o,d,t.next_out-d)),t.data_type=n.bits+(n.last?64:0)+(n.mode===rr?128:0)+(n.mode===su||n.mode===Gd?256:0),(f===0&&d===0||e===uw)&&N===Bi&&(N=yF),N},CF=t=>{if(ki(t))return hn;let e=t.state;return e.window&&(e.window=null),t.state=null,Bi},IF=(t,e)=>{if(ki(t))return hn;const n=t.state;return n.wrap&2?(n.head=e,e.done=!1,Bi):hn},TF=(t,e)=>{const n=e.length;let r,o,i;return ki(t)||(r=t.state,r.wrap!==0&&r.mode!==ou)?hn:r.mode===ou&&(o=1,o=Ld(o,e,n,0),o!==r.check)?fw:(i=Vw(t,e,n,n),i?(r.mode=Pw,hw):(r.havedict=1,Bi))};var DF=zw,BF=Uw,kF=Nw,_F=AF,RF=Gw,FF=SF,MF=CF,PF=IF,LF=TF,OF="pako inflate (from Nodeca project)",ir={inflateReset:DF,inflateReset2:BF,inflateResetKeep:kF,inflateInit:_F,inflateInit2:RF,inflate:FF,inflateEnd:MF,inflateGetHeader:PF,inflateSetDictionary:LF,inflateInfo:OF};function NF(){this.text=0,this.time=0,this.xflags=0,this.os=0,this.extra=null,this.extra_len=0,this.name="",this.comment="",this.hcrc=0,this.done=!1}var zF=NF;const jw=Object.prototype.toString,{Z_NO_FLUSH:UF,Z_FINISH:GF,Z_OK:Ma,Z_STREAM_END:qd,Z_NEED_DICT:Wd,Z_STREAM_ERROR:HF,Z_DATA_ERROR:qw,Z_MEM_ERROR:VF}=tw;function cu(t){this.options=nw.assign({chunkSize:1024*64,windowBits:15,to:""},t||{});const e=this.options;e.raw&&e.windowBits>=0&&e.windowBits<16&&(e.windowBits=-e.windowBits,e.windowBits===0&&(e.windowBits=-15)),e.windowBits>=0&&e.windowBits<16&&!(t&&t.windowBits)&&(e.windowBits+=32),e.windowBits>15&&e.windowBits<48&&(e.windowBits&15||(e.windowBits|=15)),this.err=0,this.msg="",this.ended=!1,this.chunks=[],this.strm=new sF,this.strm.avail_out=0;let n=ir.inflateInit2(this.strm,e.windowBits);if(n!==Ma)throw new Error(Od[n]);if(this.header=new zF,ir.inflateGetHeader(this.strm,this.header),e.dictionary&&(typeof e.dictionary=="string"?e.dictionary=Nd.string2buf(e.dictionary):jw.call(e.dictionary)==="[object ArrayBuffer]"&&(e.dictionary=new Uint8Array(e.dictionary)),e.raw&&(n=ir.inflateSetDictionary(this.strm,e.dictionary),n!==Ma)))throw new Error(Od[n])}cu.prototype.push=function(t,e){const n=this.strm,r=this.options.chunkSize,o=this.options.dictionary;let i,s,a;if(this.ended)return!1;for(e===~~e?s=e:s=e===!0?GF:UF,jw.call(t)==="[object ArrayBuffer]"?n.input=new Uint8Array(t):n.input=t,n.next_in=0,n.avail_in=n.input.length;;){for(n.avail_out===0&&(n.output=new Uint8Array(r),n.next_out=0,n.avail_out=r),i=ir.inflate(n,s),i===Wd&&o&&(i=ir.inflateSetDictionary(n,o),i===Ma?i=ir.inflate(n,s):i===qw&&(i=Wd));n.avail_in>0&&i===qd&&n.state.wrap>0&&t[n.next_in]!==0;)ir.inflateReset(n),i=ir.inflate(n,s);switch(i){case HF:case qw:case Wd:case VF:return this.onEnd(i),this.ended=!0,!1}if(a=n.avail_out,n.next_out&&(n.avail_out===0||i===qd))if(this.options.to==="string"){let c=Nd.utf8border(n.output,n.next_out),l=n.next_out-c,u=Nd.buf2string(n.output,c);n.next_out=l,n.avail_out=r-l,l&&n.output.set(n.output.subarray(c,c+l),0),this.onData(u)}else this.onData(n.output.length===n.next_out?n.output:n.output.subarray(0,n.next_out));if(!(i===Ma&&a===0)){if(i===qd)return i=ir.inflateEnd(this.strm),this.onEnd(i),this.ended=!0,!0;if(n.avail_in===0)break}}return!0},cu.prototype.onData=function(t){this.chunks.push(t)},cu.prototype.onEnd=function(t){t===Ma&&(this.options.to==="string"?this.result=this.chunks.join(""):this.result=nw.flattenChunks(this.chunks)),this.chunks=[],this.err=t,this.msg=this.strm.msg};function jF(t,e){const n=new cu(e);if(n.push(t),n.err)throw n.msg||Od[n.err];return n.result}function qF(t,e){return e=e||{},e.raw=!0,jF(t,e)}var WF=qF,YF={inflateRaw:WF};const{inflateRaw:QF}=YF;var ZF=QF;function XF(t){return ZF(t.subarray(2))}let KF=class extends Error{constructor(e){super(e),this.code="ERR_ABORTED"}};function JF(t){t.sort((o,i)=>o.offset-i.offset);const e=[];let n,r;for(const o of t)n&&r&&o.offset-r<=2e3?(n.length=n.length+o.length-r+o.offset,n.blocks.push(o)):e.push(n={blocks:[o],length:o.length,offset:o.offset}),r=n.offset+n.length;return e}function lu(t){if(t&&t.aborted)if(typeof DOMException>"u"){const e=new KF("aborted");throw 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K9(this._glHelper),requestLayoutReflow:()=>{},updateTooltip:this.updateTooltip.bind(this),getNamedDataFromProvider:this.getNamedDataFromProvider.bind(this),getCurrentHover:()=>this._currentHover,setDataLoadingStatus:(a,c,u)=>{this._loadingViews.set(a,{status:c,detail:u}),this._updateLoadingIndicators()},addKeyboardListener:(a,c)=>{document.addEventListener(a,c);let u=this._keyboardListeners.get(a);u||(u=[],this._keyboardListeners.set(a,u)),u.push(c)},addBroadcastListener(a,c){const u=e._extraBroadcastListeners;let l=u.get(a);l||(l=new Set,u.set(a,l)),l.add(c)},removeBroadcastListener(a,c){var l;(l=e._extraBroadcastListeners.get(a))==null||l.delete(c)},isViewConfiguredVisible:e.viewVisibilityPredicate,isViewSpec:a=>e.viewFactory.isViewSpec(a),createOrImportView:async function(a,c,u,l,f){return e.viewFactory.createOrImportView(a,t,c,u,l,f)},highlightView:a=>{var c;if((c=this.container.querySelector(".view-highlight"))==null||c.remove(),a){if(!a.isConfiguredVisible())return;const u=a.coords;if(u){const l=document.createElement("div");l.className="view-highlight",l.style.position="absolute",l.style.left=u.x+"px",l.style.top=u.y+"px",l.style.width=u.width+"px",l.style.height=u.height+"px",l.style.border="1px solid green",l.style.backgroundColor="rgba(0, 255, 0, 0.1)",l.style.pointerEvents="none",this.container.appendChild(l)}}}},r=this.spec;r.datasets&&this.registerNamedDataProvider(a=>r.datasets[a]),this.viewRoot=await t.createOrImportView(r,null,null,Hy),E(this,vt,Mu).style.flexGrow=this.viewRoot.getSize().height.grow>0?"1":"0",O(this,vt,Mx).call(this),pI(this.viewRoot),mI(this.viewRoot),this.viewRoot.getDescendants().forEach(a=>a.configureViewOpacity()),this._glHelper.invalidateSize(),O(this,vt,Rx).call(this);const{dataFlow:s,graphicsPromises:o}=L9(this.viewRoot,t.dataFlow);this.broadcast("dataFlowBuilt",s),await t.fontManager.waitUntilReady(),await G9(this.viewRoot,new Set(s.dataSources)),await 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a=setTimeout(()=>{r=!0,this.tooltip.sticky=!0},400),c=()=>clearTimeout(a);document.addEventListener("mouseup",c,{once:!0}),document.addEventListener("mousemove",c,{once:!0})}}),e.addEventListener("dragstart",s=>s.stopPropagation()),e.addEventListener("mouseout",()=>{this.tooltip.clear(),this._currentHover=null})}_handlePicking(e,t){var o;const r=this.dpr,i=p5(this._glHelper.gl,this._glHelper._pickingBufferInfo,e*r,t*r),s=i[0]|i[1]<<8|i[2]<<16|i[3]<<24;if(s==0){this._currentHover=null;return}if(s!==((o=this._currentHover)==null?void 0:o.uniqueId)&&(this._currentHover=null),this._currentHover||this.viewRoot.visit(a=>{if(a instanceof ft){if(a.mark.isPickingParticipant()&&[...a.facetCoords.values()].some(c=>c.containsPoint(e,t))){const c=a.getCollector().findDatumByUniqueId(s);c&&(this._currentHover={mark:a.mark,datum:c,uniqueId:s})}if(this._currentHover)return Go}}),this._currentHover){const a=this._currentHover.mark;this.updateTooltip(this._currentHover.datum,async c=>{if(!a.isPickingParticipant())return;const u=a.properties.tooltip;if(u!==null){const l=(u==null?void 0:u.handler)??"default",f=this.tooltipHandlers[l];if(!f)throw new Error("No such tooltip handler: "+l);return f(c,a,u==null?void 0:u.params)}})}}updateTooltip(e,t){if(!this._tooltipUpdateRequested||!e)this.tooltip.updateWithDatum(e,t),this._tooltipUpdateRequested=!0;else throw new Error("Tooltip has already been updated! 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e;a--,u+=r[s++]<<l,l+=8}t.head&&(t.head.time=u),t.flags&512&&(P[0]=u&255,P[1]=u>>>8&255,P[2]=u>>>16&255,P[3]=u>>>24&255,t.check=Xt(t.check,P,4,0)),u=0,l=0,t.mode=p2;case p2:for(;l<16;){if(a===0)break e;a--,u+=r[s++]<<l,l+=8}t.head&&(t.head.xflags=u&255,t.head.os=u>>8),t.flags&512&&(P[0]=u&255,P[1]=u>>>8&255,t.check=Xt(t.check,P,2,0)),u=0,l=0,t.mode=m2;case m2:if(t.flags&1024){for(;l<16;){if(a===0)break e;a--,u+=r[s++]<<l,l+=8}t.length=u,t.head&&(t.head.extra_len=u),t.flags&512&&(P[0]=u&255,P[1]=u>>>8&255,t.check=Xt(t.check,P,2,0)),u=0,l=0}else t.head&&(t.head.extra=null);t.mode=g2;case g2:if(t.flags&1024&&(h=t.length,h>a&&(h=a),h&&(t.head&&(v=t.head.extra_len-t.length,t.head.extra||(t.head.extra=new Array(t.head.extra_len)),Yn(t.head.extra,r,s,h,v)),t.flags&512&&(t.check=Xt(t.check,r,h,s)),a-=h,s+=h,t.length-=h),t.length))break e;t.length=0,t.mode=y2;case y2:if(t.flags&2048){if(a===0)break e;h=0;do v=r[s+h++],t.head&&v&&t.length<65536&&(t.head.name+=String.fromCharCode(v));while(v&&h<a);if(t.flags&512&&(t.check=Xt(t.check,r,h,s)),a-=h,s+=h,v)break e}else t.head&&(t.head.name=null);t.length=0,t.mode=b2;case b2:if(t.flags&4096){if(a===0)break e;h=0;do v=r[s+h++],t.head&&v&&t.length<65536&&(t.head.comment+=String.fromCharCode(v));while(v&&h<a);if(t.flags&512&&(t.check=Xt(t.check,r,h,s)),a-=h,s+=h,v)break e}else t.head&&(t.head.comment=null);t.mode=x2;case x2:if(t.flags&512){for(;l<16;){if(a===0)break e;a--,u+=r[s++]<<l,l+=8}if(u!==(t.check&65535)){n.msg="header crc mismatch",t.mode=Ae;break}u=0,l=0}t.head&&(t.head.hcrc=t.flags>>9&1,t.head.done=!0),n.adler=t.check=0,t.mode=hn;break;case A2:for(;l<32;){if(a===0)break e;a--,u+=r[s++]<<l,l+=8}n.adler=t.check=R2(u),u=0,l=0,t.mode=du;case du:if(t.havedict===0)return n.next_out=o,n.avail_out=c,n.next_in=s,n.avail_in=a,t.hold=u,t.bits=l,mB;n.adler=t.check=1,t.mode=hn;case hn:case kh:if(t.last){u>>>=l&7,l-=l&7,t.mode=Ph;break}for(;l<3;){if(a===0)break e;a--,u+=r[s++]<<l,l+=8}switch(t.last=u&1,u>>>=1,l-=1,u&3){case 0:t.mode=w2;break;case 1:CB(t),t.mode=pu;break;case 2:t.mode=S2;break;case 3:n.msg="invalid block type",t.mode=Ae}u>>>=2,l-=2;break;case w2:for(u>>>=l&7,l-=l&7;l<32;){if(a===0)break e;a--,u+=r[s++]<<l,l+=8}if((u&65535)!==(u>>>16^65535)){n.msg="invalid stored block lengths",t.mode=Ae;break}t.length=u&65535,u=0,l=0,t.mode=Fh;case Fh:t.mode=v2;case v2:if(h=t.length,h){if(h>a&&(h=a),h>c&&(h=c),h===0)break e;Yn(i,r,s,h,o),a-=h,s+=h,c-=h,o+=h,t.length-=h;break}t.mode=hn;break;case S2:for(;l<14;){if(a===0)break e;a--,u+=r[s++]<<l,l+=8}if(t.nlen=(u&31)+257,u>>>=5,l-=5,t.ndist=(u&31)+1,u>>>=5,l-=5,t.ncode=(u&15)+4,u>>>=4,l-=4,t.nlen>286||t.ndist>30){n.msg="too many length or distance symbols",t.mode=Ae;break}t.have=0,t.mode=E2;case E2:for(;t.have<t.ncode;){for(;l<3;){if(a===0)break e;a--,u+=r[s++]<<l,l+=8}t.lens[L[t.have++]]=u&7,u>>>=3,l-=3}for(;t.have<19;)t.lens[L[t.have++]]=0;if(t.lencode=t.lendyn,t.lenbits=7,F={bits:t.lenbits},T=Wo(dB,t.lens,0,19,t.lencode,0,t.work,F),t.lenbits=F.bits,T){n.msg="invalid code lengths set",t.mode=Ae;break}t.have=0,t.mode=C2;case C2:for(;t.have<t.nlen+t.ndist;){for(;g=t.lencode[u&(1<<t.lenbits)-1],y=g>>>24,x=g>>>16&255,A=g&65535,!(y<=l);){if(a===0)break e;a--,u+=r[s++]<<l,l+=8}if(A<16)u>>>=y,l-=y,t.lens[t.have++]=A;else{if(A===16){for(k=y+2;l<k;){if(a===0)break e;a--,u+=r[s++]<<l,l+=8}if(u>>>=y,l-=y,t.have===0){n.msg="invalid bit length repeat",t.mode=Ae;break}v=t.lens[t.have-1],h=3+(u&3),u>>>=2,l-=2}else if(A===17){for(k=y+3;l<k;){if(a===0)break e;a--,u+=r[s++]<<l,l+=8}u>>>=y,l-=y,v=0,h=3+(u&7),u>>>=3,l-=3}else{for(k=y+7;l<k;){if(a===0)break e;a--,u+=r[s++]<<l,l+=8}u>>>=y,l-=y,v=0,h=11+(u&127),u>>>=7,l-=7}if(t.have+h>t.nlen+t.ndist){n.msg="invalid bit length repeat",t.mode=Ae;break}for(;h--;)t.lens[t.have++]=v}}if(t.mode===Ae)break;if(t.lens[256]===0){n.msg="invalid code -- missing end-of-block",t.mode=Ae;break}if(t.lenbits=9,F={bits:t.lenbits},T=Wo(s2,t.lens,0,t.nlen,t.lencode,0,t.work,F),t.lenbits=F.bits,T){n.msg="invalid literal/lengths set",t.mode=Ae;break}if(t.distbits=6,t.distcode=t.distdyn,F={bits:t.distbits},T=Wo(o2,t.lens,t.nlen,t.ndist,t.distcode,0,t.work,F),t.distbits=F.bits,T){n.msg="invalid distances set",t.mode=Ae;break}t.mode=pu;case pu:t.mode=mu;case mu:if(a>=6&&c>=258){n.next_out=o,n.avail_out=c,n.next_in=s,n.avail_in=a,t.hold=u,t.bits=l,cB(n,d),o=n.next_out,i=n.output,c=n.avail_out,s=n.next_in,r=n.input,a=n.avail_in,u=t.hold,l=t.bits,t.mode===hn&&(t.back=-1);break}for(t.back=0;g=t.lencode[u&(1<<t.lenbits)-1],y=g>>>24,x=g>>>16&255,A=g&65535,!(y<=l);){if(a===0)break e;a--,u+=r[s++]<<l,l+=8}if(x&&!(x&240)){for(w=y,S=x,C=A;g=t.lencode[C+((u&(1<<w+S)-1)>>w)],y=g>>>24,x=g>>>16&255,A=g&65535,!(w+y<=l);){if(a===0)break e;a--,u+=r[s++]<<l,l+=8}u>>>=w,l-=w,t.back+=w}if(u>>>=y,l-=y,t.back+=y,t.length=A,x===0){t.mode=k2;break}if(x&32){t.back=-1,t.mode=hn;break}if(x&64){n.msg="invalid literal/length code",t.mode=Ae;break}t.extra=x&15,t.mode=D2;case D2:if(t.extra){for(k=t.extra;l<k;){if(a===0)break e;a--,u+=r[s++]<<l,l+=8}t.length+=u&(1<<t.extra)-1,u>>>=t.extra,l-=t.extra,t.back+=t.extra}t.was=t.length,t.mode=I2;case I2:for(;g=t.distcode[u&(1<<t.distbits)-1],y=g>>>24,x=g>>>16&255,A=g&65535,!(y<=l);){if(a===0)break e;a--,u+=r[s++]<<l,l+=8}if(!(x&240)){for(w=y,S=x,C=A;g=t.distcode[C+((u&(1<<w+S)-1)>>w)],y=g>>>24,x=g>>>16&255,A=g&65535,!(w+y<=l);){if(a===0)break e;a--,u+=r[s++]<<l,l+=8}u>>>=w,l-=w,t.back+=w}if(u>>>=y,l-=y,t.back+=y,x&64){n.msg="invalid distance code",t.mode=Ae;break}t.offset=A,t.extra=x&15,t.mode=T2;case T2:if(t.extra){for(k=t.extra;l<k;){if(a===0)break e;a--,u+=r[s++]<<l,l+=8}t.offset+=u&(1<<t.extra)-1,u>>>=t.extra,l-=t.extra,t.back+=t.extra}if(t.offset>t.dmax){n.msg="invalid distance too far back",t.mode=Ae;break}t.mode=B2;case B2:if(c===0)break e;if(h=d-c,t.offset>h){if(h=t.offset-h,h>t.whave&&t.sane){n.msg="invalid distance too far back",t.mode=Ae;break}h>t.wnext?(h-=t.wnext,p=t.wsize-h):p=t.wnext-h,h>t.length&&(h=t.length),m=t.window}else m=i,p=o-t.offset,h=t.length;h>c&&(h=c),c-=h,t.length-=h;do i[o++]=m[p++];while(--h);t.length===0&&(t.mode=mu);break;case k2:if(c===0)break e;i[o++]=t.length,c--,t.mode=mu;break;case Ph:if(t.wrap){for(;l<32;){if(a===0)break e;a--,u|=r[s++]<<l,l+=8}if(d-=c,n.total_out+=d,t.total+=d,d&&(n.adler=t.check=t.flags?Xt(t.check,i,d,o-d):Th(t.check,i,d,o-d)),d=c,(t.flags?u:R2(u))!==t.check){n.msg="incorrect data check",t.mode=Ae;break}u=0,l=0}t.mode=F2;case F2:if(t.wrap&&t.flags){for(;l<32;){if(a===0)break e;a--,u+=r[s++]<<l,l+=8}if(u!==(t.total&4294967295)){n.msg="incorrect length check",t.mode=Ae;break}u=0,l=0}t.mode=P2;case P2:T=pB;break e;case Ae:T=c2;break e;case M2:return u2;case yB:default:return xt}return n.next_out=o,n.avail_out=c,n.next_in=s,n.avail_in=a,t.hold=u,t.bits=l,(t.wsize||d!==n.avail_out&&t.mode<Ae&&(t.mode<Ph||e!==a2))&&N2(n,n.output,n.next_out,d-n.avail_out),f-=n.avail_in,d-=n.avail_out,n.total_in+=f,n.total_out+=d,t.total+=d,t.wrap&&d&&(n.adler=t.check=t.flags?Xt(t.check,i,d,n.next_out-d):Th(t.check,i,d,n.next_out-d)),n.data_type=t.bits+(t.last?64:0)+(t.mode===hn?128:0)+(t.mode===pu||t.mode===Fh?256:0),(f===0&&d===0||e===a2)&&T===Gr&&(T=gB),T}function IB(n){if(!n||!n.state)return xt;var e=n.state;return e.window&&(e.window=null),n.state=null,Gr}function TB(n,e){var t;return!n||!n.state||(t=n.state,!(t.wrap&2))?xt:(t.head=e,e.done=!1,Gr)}function L2(n,e){var t=e.length,r,i,s;return!n||!n.state||(r=n.state,r.wrap!==0&&r.mode!==du)?xt:r.mode===du&&(i=1,i=Th(i,e,t,0),i!==r.check)?c2:(s=N2(n,e,t,t),s?(r.mode=M2,u2):(r.havedict=1,Gr))}const Oh={2:"need dictionary",1:"stream end",0:"","-1":"file error","-2":"stream error","-3":"data error","-4":"insufficient memory","-5":"buffer error","-6":"incompatible version"};function BB(){this.input=null,this.next_in=0,this.avail_in=0,this.total_in=0,this.output=null,this.next_out=0,this.avail_out=0,this.total_out=0,this.msg="",this.state=null,this.data_type=2,this.adler=0}var Nh=Object.prototype.toString;class dn{constructor(e){if(!(this instanceof dn))return new dn(e);this.options=eB({chunkSize:16384,windowBits:0,to:""},e||{});var t=this.options;t.raw&&t.windowBits>=0&&t.windowBits<16&&(t.windowBits=-t.windowBits,t.windowBits===0&&(t.windowBits=-15)),t.windowBits>=0&&t.windowBits<16&&!(e&&e.windowBits)&&(t.windowBits+=32),t.windowBits>15&&t.windowBits<48&&(t.windowBits&15||(t.windowBits|=15)),this.err=0,this.msg="",this.ended=!1,this.chunks=[],this.strm=new BB,this.strm.avail_out=0;var r=EB(this.strm,t.windowBits);if(r!==Ur)throw new Error(Oh[r]);if(this.header=new sB,TB(this.strm,this.header),t.dictionary&&(typeof t.dictionary=="string"?t.dictionary=$y(t.dictionary):Nh.call(t.dictionary)==="[object ArrayBuffer]"&&(t.dictionary=new Uint8Array(t.dictionary)),t.raw&&(r=L2(this.strm,t.dictionary),r!==Ur)))throw new Error(Oh[r])}push(e,t){var r=this.strm,i=this.options.chunkSize,s=this.options.dictionary,o,a,c,u,l,f,d=!1;if(this.ended)return!1;a=t===~~t?t:t===!0?lu:Xy,typeof e=="string"?r.input=nB(e):Nh.call(e)==="[object ArrayBuffer]"?r.input=new Uint8Array(e):r.input=e,r.next_in=0,r.avail_in=r.input.length;do{if(r.avail_out===0&&(r.output=Ni(i),r.next_out=0,r.avail_out=i),o=DB(r,Xy),o===KT&&s&&(typeof s=="string"?f=$y(s):Nh.call(s)==="[object ArrayBuffer]"?f=new Uint8Array(s):f=s,o=L2(this.strm,f)),o===JT&&d===!0&&(o=Ur,d=!1),o!==fu&&o!==Ur)return this.onEnd(o),this.ended=!0,!1;r.next_out&&(r.avail_out===0||o===fu||r.avail_in===0&&(a===lu||a===zr))&&(this.options.to==="string"?(c=iB(r.output,r.next_out),u=r.next_out-c,l=rB(r.output,c),r.next_out=u,r.avail_out=i-u,u&&Yn(r.output,r.output,c,u,0),this.onData(l)):this.onData(Zy(r.output,r.next_out))),r.avail_in===0&&r.avail_out===0&&(d=!0)}while((r.avail_in>0||r.avail_out===0)&&o!==fu);return o===fu&&(a=lu),a===lu?(o=IB(this.strm),this.onEnd(o),this.ended=!0,o===Ur):(a===zr&&(this.onEnd(Ur),r.avail_out=0),!0)}onData(e){this.chunks.push(e)}onEnd(e){e===Ur&&(this.options.to==="string"?this.result=this.chunks.join(""):this.result=Dh(this.chunks)),this.chunks=[],this.err=e,this.msg=this.strm.msg}}function kB(n,e){var t=new dn(e);if(t.push(n,!0),t.err)throw t.msg||Oh[t.err];return t.result}function FB(n,e){return e=e||{},e.raw=!0,kB(n,e)}function PB(n){let e=0;for(const t of n)e+=t.length;return e}function z2(n,e){const t=new Uint8Array(e??PB(n));let r=0;for(const i of n)t.set(i,r),r+=i.length;return t}async function MB(n){try{let e,t=0,r;const i=[];let s=0;do{const o=n.subarray(t);if(r=new dn(void 0),{strm:e}=r,r.push(o,zr),r.err)throw new Error(r.msg);t+=e.next_in;const a=r.result;i.push(a),s+=a.length}while(e.avail_in);return z2(i,s)}catch(e){throw/incorrect header check/.exec(`${e}`)?new Error("problem decompressing block: incorrect gzip header check"):e}}class U2{constructor({filehandle:e,gziFilehandle:t}){Y(this,"filehandle");Y(this,"gzi");this.filehandle=e,this.gzi=new ZT({filehandle:t})}async _readAndUncompressBlock(e,t){let r=t;r||(r=(await this.filehandle.stat()).size);const i=r-e,s=await this.filehandle.read(i,e);return MB(s)}async read(e,t){const r=await this.gzi.getRelevantBlocksForRead(e,t),i=[];for(let s=0;s<r.length-1;s+=1){const o=await this._readAndUncompressBlock(r[s][0],r[s+1][0]),[,a]=r[s],c=a>=t?0:t-a,u=Math.min(t+e,a+o.length)-a;c>=0&&c<o.length&&i.push(o.subarray(c,u))}return z2(i)}}function G2(n,e){return n.offset+n.lineBytes*Math.floor(e/n.lineLength)+e%n.lineLength}async function RB(n,e={}){const t=new TextDecoder("utf8");return Object.fromEntries(t.decode(await n.readFile(e)).split(/\r?\n/).map(r=>r.trim()).filter(r=>!!r).map(r=>r.split("	")).map(r=>{var i;if((i=r[0])!=null&&i.startsWith(">"))throw new Error("found > in sequence name, might have supplied FASTA file for the FASTA index");return[r[0],{name:r[0],length:+r[1],start:0,end:+r[1],offset:+r[2],lineLength:+r[3],lineBytes:+r[4]}]}))}class H2{constructor({fasta:e,fai:t,path:r,faiPath:i}){if(e)this.fasta=e;else if(r)this.fasta=new qe(r);else throw new Error("Need to pass filehandle for fasta or path to localfile");if(t)this.fai=t;else if(i)this.fai=new qe(i);else if(r)this.fai=new qe(`${r}.fai`);else throw new Error("Need to pass filehandle for  or path to localfile")}async _getIndexes(e){return this.indexes||(this.indexes=RB(this.fai,e).catch(t=>{throw this.indexes=void 0,t})),this.indexes}async getSequenceNames(e){return Object.keys(await this._getIndexes(e))}async getSequenceSizes(e){const t={},r=await this._getIndexes(e);for(const i of Object.values(r))t[i.name]=i.length;return t}async getSequenceSize(e,t){var i;return(i=(await this._getIndexes(t))[e])==null?void 0:i.length}async hasReferenceSequence(e,t){return!!(await this._getIndexes(t))[e]}async getResiduesByName(e,t,r,i){const s=(await this._getIndexes(i))[e];return s?this._fetchFromIndexEntry(s,t,r,i):void 0}async getSequence(e,t,r,i){return this.getResiduesByName(e,t,r,i)}async _fetchFromIndexEntry(e,t=0,r,i){let s=r;if(t<0)throw new TypeError("regionStart cannot be less than 0");if((s===void 0||s>e.length)&&(s=e.length),t>=s)return"";const o=G2(e,t),a=G2(e,s)-o;return new TextDecoder("utf8").decode(await this.fasta.read(a,o,i)).replace(/\s+/g,"")}}class OB extends H2{constructor({fasta:e,path:t,fai:r,faiPath:i,gzi:s,gziPath:o}){super({fasta:e,path:t,fai:r,faiPath:i}),e&&s?this.fasta=new U2({filehandle:e,gziFilehandle:s}):t&&o&&(this.fasta=new 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DOMException>"u"){const e=new Pk("aborted");throw e.code="ERR_ABORTED",e}else throw new DOMException("aborted","AbortError")}const Wh=typeof TextDecoder<"u"?new TextDecoder("utf8"):void 0;function qh(n,e,t,r){return n<r&&e>=t}class bb{constructor(e,t,r,i,s){Y(this,"bbi");Y(this,"refsByName");Y(this,"cirTreeOffset");Y(this,"isCompressed");Y(this,"blockType");Y(this,"cirTreePromise");Y(this,"featureCache",new _i({cache:new Vr({maxSize:1e3}),fill:async({length:e,offset:t},r)=>this.bbi.read(e,t,{signal:r})}));if(this.bbi=e,this.refsByName=t,this.cirTreeOffset=r,this.isCompressed=i,this.blockType=s,!(r>=0))throw new Error("invalid cirTreeOffset!")}async readWigData(e,t,r,i,s){try{const o=this.refsByName[e];o===void 0&&i.complete();const a={chrId:o,start:t,end:r};this.cirTreePromise||(this.cirTreePromise=this.bbi.read(48,this.cirTreeOffset,s));const c=await this.cirTreePromise,l=new DataView(c.buffer).getUint32(4,!0);let f=[],d=0;const h=(y,x,A)=>{try{const S=y.subarray(x),C=new DataView(S.buffer,S.byteOffset,S.length);let v=0;const T=C.getUint8(v);v+=2;const P=C.getUint16(v,!0);if(v+=2,T===1){const F=[];for(let k=0;k<P;k++){const L=C.getUint32(v,!0);v+=4;const U=C.getUint32(v,!0);v+=4;const j=C.getUint32(v,!0);v+=4;const K=C.getUint32(v,!0);v+=4;const _=Number(C.getBigUint64(v,!0));v+=8;const te=Number(C.getBigUint64(v,!0));v+=8,F.push({startChrom:L,startBase:U,endBase:K,endChrom:j,blockOffset:_,blockSize:te,offset:v})}f=f.concat(F.filter(k=>p(k)).map(k=>({offset:k.blockOffset,length:k.blockSize})))}else if(T===0){const F=[];for(let L=0;L<P;L++){const U=C.getUint32(v,!0);v+=4;const j=C.getUint32(v,!0);v+=4;const K=C.getUint32(v,!0);v+=4;const _=C.getUint32(v,!0);v+=4;const te=Number(C.getBigUint64(v,!0));v+=8,F.push({startChrom:U,startBase:j,endChrom:K,endBase:_,blockOffset:te,offset:v})}const k=F.filter(L=>p(L)).map(L=>L.blockOffset);k.length>0&&g(k,A+1)}}catch(w){i.error(w)}},p=y=>{const{startChrom:x,startBase:A,endChrom:w,endBase:S}=y;return(x<o||x===o&&A<=r)&&(w>o||w===o&&S>=t)},m=async(y,x,A)=>{try{const w=x.max-x.min,S=x.min,C=await this.featureCache.get(`${w}_${S}`,{length:w,offset:S},s==null?void 0:s.signal);for(const v of y)x.contains(v)&&(h(C,v-S,A),d-=1,d===0&&this.readFeatures(i,f,{...s,request:a}).catch(T=>{i.error(T)}))}catch(w){i.error(w)}},g=(y,x)=>{try{d+=y.length;const A=4+l*32;let w=new ji([{min:y[0],max:y[0]+A}]);for(let S=1;S<y.length;S+=1){const C=new ji([{min:y[S],max:y[S]+A}]);w=w.union(C)}w.getRanges().map(S=>m(y,S,x))}catch(A){i.error(A)}};g([this.cirTreeOffset+48],1);return}catch(o){i.error(o)}}parseSummaryBlock(e,t,r){const i=[];let s=t;const o=new DataView(e.buffer,e.byteOffset,e.length);for(;s<e.byteLength;){const a=o.getUint32(s,!0);s+=4;const c=o.getUint32(s,!0);s+=4;const u=o.getUint32(s,!0);s+=4;const l=o.getUint32(s,!0);s+=4;const f=o.getFloat32(s,!0);s+=4;const d=o.getFloat32(s,!0);s+=4;const h=o.getFloat32(s,!0);s+=4,s+=4,(!r||a===r.chrId&&qh(c,u,r.start,r.end))&&i.push({start:c,end:u,maxScore:d,minScore:f,summary:!0,score:h/(l||1)})}return i}parseBigBedBlock(e,t,r,i){const s=[];let o=t;const a=e,c=new DataView(a.buffer,a.byteOffset,a.length);for(;o<e.byteLength;){const u=o,l=c.getUint32(o,!0);o+=4;const f=c.getInt32(o,!0);o+=4;const d=c.getInt32(o,!0);o+=4;let h=o;for(;h<e.length&&e[h]!==0;h++);const p=e.subarray(o,h),m=(Wh==null?void 0:Wh.decode(p))??p.toString();o=h+1,s.push({chromId:l,start:f,end:d,rest:m,uniqueId:`bb-${r+u}`})}return i?s.filter(u=>qh(u.start,u.end,i.start,i.end)):s}parseBigWigBlock(e,t,r){const i=e.subarray(t),s=new DataView(i.buffer,i.byteOffset,i.length);let o=0;o+=4;const a=s.getInt32(o,!0);o+=8;const c=s.getUint32(o,!0);o+=4;const u=s.getUint32(o,!0);o+=4;const l=s.getUint8(o);o+=2;const f=s.getUint16(o,!0);o+=2;const d=new Array(f);switch(l){case 1:{for(let h=0;h<f;h++){const 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d=Number(i.getBigUint64(o,!0));o+=8;const h=i.getUint16(o,!0);o+=2;const p=i.getUint16(o,!0);o+=2;const m=Number(i.getBigUint64(o,!0));o+=8;const g=Number(i.getBigUint64(o,!0));o+=8;const y=i.getUint32(o,!0);o+=4;const x=Number(i.getBigUint64(o,!0));o+=8;const A=[];for(let v=0;v<u;v++){const T=i.getUint32(o,!0);o+=4;const P=i.getUint32(o,!0);o+=4;const F=Number(i.getBigUint64(o,!0));o+=8;const k=Number(i.getBigUint64(o,!0));o+=8,A.push({reductionLevel:T,reserved:P,dataOffset:F,indexOffset:k})}const w=a===xb?"bigbed":"bigwig";if(m>t||g>t-8*5)return this._getMainHeader(e,t*2);let S;if(g){const v=r.subarray(g);let T=0;const P=Qi(v),F=Number(P.getBigUint64(T,!0));T+=8;const k=P.getFloat64(T,!0);T+=8;const L=P.getFloat64(T,!0);T+=8;const U=P.getFloat64(T,!0);T+=8;const j=P.getFloat64(T,!0);T+=8,S={scoreMin:k,scoreMax:L,scoreSum:U,scoreSumSquares:j,basesCovered:F}}else throw new Error("no stats");const C=new TextDecoder("utf8");return{zoomLevels:A,magic:a,extHeaderOffset:x,numZoomLevels:u,fieldCount:h,totalSummary:S,definedFieldCount:p,uncompressBufSize:y,asOffset:m,chromTreeOffset:l,totalSummaryOffset:g,unzoomedDataOffset:f,unzoomedIndexOffset:d,fileType:w,version:c,autoSql:m?C.decode(r.subarray(m,r.indexOf(0,m))):""}}async _readChromTree(e,t){const r=[],i={},s=e.chromTreeOffset,o=Qi(await this.bbi.read(32,s,t));let a=0;a+=4,a+=4;const c=o.getUint32(a,!0);a+=4;const u=o.getUint32(a,!0);a+=4,a+=8;const l=new TextDecoder("utf8"),f=async d=>{const h=await this.bbi.read(4,d),p=Qi(h);let m=0;const g=p.getUint8(m);m+=1,m+=1;const y=p.getUint16(m,!0);if(m+=2,g){const x=await this.bbi.read(y*(c+u),d+m),A=Qi(x);m=0;for(let w=0;w<y;w++){const S=l.decode(x.subarray(m,m+c)).replaceAll("\0","");m+=c;const C=A.getUint32(m,!0);m+=4;const v=A.getUint32(m,!0);m+=4,i[this.renameRefSeqs(S)]=C,r[C]={name:S,id:C,length:v}}}else{const x=[],A=Qi(await this.bbi.read(y*(c+8),d+m));m=0;for(let w=0;w<y;w++){m+=c;const S=Number(A.getBigUint64(m,!0));m+=8,x.push(f(S))}await Promise.all(x)}};return await f(s+32),{refsByName:i,refsByNumber:r}}async getUnzoomedView(e){const{unzoomedIndexOffset:t,refsByName:r,uncompressBufSize:i,fileType:s}=await this.getHeader(e);return new bb(this.bbi,r,t,i>0,s)}async getFeatureStream(e,t,r,i){await this.getHeader(i);const s=this.renameRefSeqs(e);let o;const{basesPerSpan:a,scale:c}=i||{};return a?o=await this.getView(1/a,i):c?o=await this.getView(c,i):o=await this.getView(1,i),new At(u=>{o.readWigData(s,t,r,u,i).catch(l=>{u.error(l)})})}async getFeatures(e,t,r,i){const s=await this.getFeatureStream(e,t,r,i);return(await db(s.pipe(Ek()))).flat()}}class Ok extends Ab{async getView(e,t){const{zoomLevels:r,refsByName:i,uncompressBufSize:s}=await this.getHeader(t),o=1/e,a=r.length-1;for(let c=a;c>=0;c-=1){const u=r[c];if(u&&u.reductionLevel<=2*o)return new bb(this.bbi,i,u.indexOffset,s>0,"summary")}return this.getUnzoomedView(t)}}function Nk(n){return n.filter(e=>!!e)}class Lk extends Ab{constructor(){super(...arguments);Y(this,"readIndicesCache",new _i({cache:new Vr({maxSize:1}),fill:(t,r)=>this._readIndices({...t,signal:r})}))}readIndices(t={}){const{signal:r,...i}=t;return this.readIndicesCache.get(JSON.stringify(i),t,r)}async getView(t,r){return this.getUnzoomedView(r)}async _readIndices(t){const{extHeaderOffset:r}=await this.getHeader(t),i=await this.bbi.read(64,r),s=new DataView(i.buffer,i.byteOffset,i.length);let o=0;o+=2;const a=s.getUint16(o,!0);o+=2;const c=Number(s.getBigUint64(o,!0));if(o+=8,a===0)return[];const u=20,l=u*a,f=await this.bbi.read(l,c),d=[];for(let h=0;h<a;h+=1){const p=f.subarray(h*u),m=new DataView(p.buffer,p.byteOffset,p.length);let g=0;const y=m.getInt16(g,!0);g+=2;const x=m.getInt16(g,!0);g+=2;const A=Number(m.getBigUint64(g,!0));g+=12;const w=m.getInt16(g,!0);d.push({type:y,fieldcount:x,offset:A,field:w})}return d}async searchExtraIndexBlocks(t,r={}){const i=await this.readIndices(r);if(i.length===0)return[];const s=new TextDecoder("utf8"),o=i.map(async a=>{const{offset:c,field:u}=a,l=await this.bbi.read(32,c,r),f=new DataView(l.buffer,l.byteOffset,l.length);let d=0;d+=4;const h=f.getInt32(d,!0);d+=4;const p=f.getInt32(d,!0);d+=4;const m=f.getInt32(d,!0);d+=4,d+=8;const g=async y=>{const x=y,A=4+h*(p+m),S=await this.bbi.read(A,x,r),C=new DataView(S.buffer,S.byteOffset,S.length);let v=0;const T=C.getInt8(v);v+=2;const P=C.getInt16(v,!0);v+=2;const F=[];if(T===0){const k=[];for(let U=0;U<P;U++){const j=s.decode(S.subarray(v,v+p)).replaceAll("\0","");v+=p;const K=Number(C.getBigUint64(v,!0));v+=8,k.push({key:j,offset:K})}let L=0;for(const{key:U,offset:j}of k){if(t.localeCompare(U)<0&&L)return g(L);L=j}return g(L)}else if(T===1){for(let k=0;k<P;k++){const L=s.decode(S.subarray(v,v+p)).replaceAll("\0","");v+=p;const U=Number(C.getBigUint64(v,!0));v+=8;const j=C.getUint32(v,!0);v+=4;const 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J9=21578050;function $9(t,e){return t-t%e}function eM(t,e){return t-t%e+e}function tM(t,e){return e-=1,[[0,0],[1+(t>>26),1+(e>>26)],[9+(t>>23),9+(e>>23)],[73+(t>>20),73+(e>>20)],[585+(t>>17),585+(e>>17)],[4681+(t>>14),4681+(e>>14)]]}class Fo extends Dx{async lineCount(e,n){var r,o;return((o=(r=(await this.parse(n)).indices[e])===null||r===void 0?void 0:r.stats)===null||o===void 0?void 0:o.lineCount)||0}async _parse(e){const n=await this.filehandle.readFile(e);if(n.readUInt32LE(0)!==J9)throw new Error("Not a BAI file");const r=n.readInt32LE(4),i=((1<<(5+1)*3)-1)/7;let s=8,a;const c=new Array(r);for(let l=0;l<r;l++){const u=n.readInt32LE(s);let f;s+=4;const d={};for(let y=0;y<u;y+=1){const v=n.readUInt32LE(s);if(s+=4,v===i+1)s+=4,f=Tx(n,s+16),s+=32;else{if(v>i+1)throw new Error("bai index contains too many bins, please use CSI");{const b=n.readInt32LE(s);s+=4;const A=new Array(b);for(let S=0;S<b;S++){const E=Ro(n,s);s+=8;const I=Ro(n,s);s+=8,a=hu(a,E),A[S]=new a0(E,I,v)}d[v]=A}}}const h=n.readInt32LE(s);s+=4;const p=new Array(h);for(let y=0;y<h;y++){const v=Ro(n,s);s+=8,a=hu(a,v),p[y]=v}c[l]={binIndex:d,linearIndex:p,stats:f}}return{bai:!0,firstDataLine:a,maxBlockSize:65536,indices:c,refCount:r}}async indexCov(e,n,r,o={}){const s=n!==void 0,c=(await this.parse(o)).indices[e];if(!c)return[];const{linearIndex:l=[],stats:u}=c;if(l.length===0)return[];const f=r===void 0?(l.length-1)*16384:eM(r,16384),d=n===void 0?0:$9(n,16384),h=s?new Array((f-d)/16384):new Array(l.length-1),p=l[l.length-1].blockPosition;if(f>(l.length-1)*16384)throw new Error("query outside of range of linear index");let y=l[d/16384].blockPosition;for(let v=d/16384,b=0;v<f/16384;v++,b++)h[b]={score:l[v+1].blockPosition-y,start:v*16384,end:v*16384+16384},y=l[v+1].blockPosition;return h.map(v=>({...v,score:v.score*((u==null?void 0:u.lineCount)||0)/p}))}async blocksForRange(e,n,r,o={}){n<0&&(n=0);const i=await this.parse(o);if(!i)return[];const s=i.indices[e];if(!s)return[];const a=tM(n,r),c=[];for(const[h,p]of a)for(let y=h;y<=p;y++)if(s.binIndex[y]){const v=s.binIndex[y];for(const b of v)c.push(new a0(b.minv,b.maxv,y))}const l=s.linearIndex.length;let u;const f=Math.min(n>>14,l-1),d=Math.min(r>>14,l-1);for(let h=f;h<=d;++h){const p=s.linearIndex[h];p&&(!u||p.compareTo(u)<0)&&(u=p)}return Ix(c,u)}async parse(e={}){return this.setupP||(this.setupP=this._parse(e).catch(n=>{throw this.setupP=void 0,n})),this.setupP}async hasRefSeq(e,n={}){var r;return!!(!((r=(await this.parse(n)).indices[e])===null||r===void 0)&&r.binIndex)}}let c0=[0,1996959894,3993919788,2567524794,124634137,1886057615,3915621685,2657392035,249268274,2044508324,3772115230,2547177864,162941995,2125561021,3887607047,2428444049,498536548,1789927666,4089016648,2227061214,450548861,1843258603,4107580753,2211677639,325883990,1684777152,4251122042,2321926636,335633487,1661365465,4195302755,2366115317,997073096,1281953886,3579855332,2724688242,1006888145,1258607687,3524101629,2768942443,901097722,1119000684,3686517206,2898065728,853044451,1172266101,3705015759,2882616665,651767980,1373503546,3369554304,3218104598,565507253,1454621731,3485111705,3099436303,671266974,1594198024,3322730930,2970347812,795835527,1483230225,3244367275,3060149565,1994146192,31158534,2563907772,4023717930,1907459465,112637215,2680153253,3904427059,2013776290,251722036,2517215374,3775830040,2137656763,141376813,2439277719,3865271297,1802195444,476864866,2238001368,4066508878,1812370925,453092731,2181625025,4111451223,1706088902,314042704,2344532202,4240017532,1658658271,366619977,2362670323,4224994405,1303535960,984961486,2747007092,3569037538,1256170817,1037604311,2765210733,3554079995,1131014506,879679996,2909243462,3663771856,1141124467,855842277,2852801631,3708648649,1342533948,654459306,3188396048,3373015174,1466479909,544179635,3110523913,3462522015,1591671054,702138776,2966460450,3352799412,1504918807,783551873,3082640443,3233442989,3988292384,2596254646,62317068,1957810842,3939845945,2647816111,81470997,1943803523,3814918930,2489596804,225274430,2053790376,3826175755,2466906013,167816743,2097651377,4027552580,2265490386,503444072,1762050814,4150417245,2154129355,426522225,1852507879,4275313526,2312317920,282753626,1742555852,4189708143,2394877945,397917763,1622183637,3604390888,2714866558,953729732,1340076626,3518719985,2797360999,1068828381,1219638859,3624741850,2936675148,906185462,1090812512,3747672003,2825379669,829329135,1181335161,3412177804,3160834842,628085408,1382605366,3423369109,3138078467,570562233,1426400815,3317316542,2998733608,733239954,1555261956,3268935591,3050360625,752459403,1541320221,2607071920,3965973030,1969922972,40735498,2617837225,3943577151,1913087877,83908371,2512341634,3803740692,2075208622,213261112,2463272603,3855990285,2094854071,198958881,2262029012,4057260610,1759359992,534414190,2176718541,4139329115,1873836001,414664567,2282248934,4279200368,1711684554,285281116,2405801727,4167216745,1634467795,376229701,2685067896,3608007406,1308918612,956543938,2808555105,3495958263,1231636301,1047427035,2932959818,3654703836,1088359270,936918e3,2847714899,3736837829,1202900863,817233897,3183342108,3401237130,1404277552,615818150,3134207493,3453421203,1423857449,601450431,3009837614,3294710456,1567103746,711928724,3020668471,3272380065,1510334235,755167117];typeof Int32Array<"u"&&(c0=new Int32Array(c0));const nM=(t,e)=>{let n=e===0?0:~~e^-1;for(let r=0;r<t.length;r++)n=c0[(n^t[r])&255]^n>>>8;return n^-1},Bx=(t,e)=>Ke.Buffer.from(t,e);function rM(t,e){const n=(r,o)=>e(Bx(r),o)>>>0;return n.signed=(r,o)=>e(Bx(r),o),n.unsigned=n,n.model=t,n}const iM=rM("crc-32",nM),oM=21582659,sM=38359875;function aM(t,e){return t*2**e}function kx(t,e){return Math.floor(t/2**e)}let du=class extends Dx{constructor(){super(...arguments),this.maxBinNumber=0,this.depth=0,this.minShift=0}async lineCount(e,n){var r,o;return((o=(r=(await this.parse(n)).indices[e])===null||r===void 0?void 0:r.stats)===null||o===void 0?void 0:o.lineCount)||0}async indexCov(){return[]}parseAuxData(e,n){const r=e.readInt32LE(n),o=r&65536?"zero-based-half-open":"1-based-closed",i={0:"generic",1:"SAM",2:"VCF"}[r&15];if(!i)throw new Error(`invalid Tabix preset format flags ${r}`);const s={ref:e.readInt32LE(n+4),start:e.readInt32LE(n+8),end:e.readInt32LE(n+12)},a=e.readInt32LE(n+16),c=a?String.fromCharCode(a):"",l=e.readInt32LE(n+20),u=e.readInt32LE(n+24);return{columnNumbers:s,coordinateType:o,metaValue:a,metaChar:c,skipLines:l,format:i,formatFlags:r,...K9(e.subarray(n+28,n+28+u),this.renameRefSeq)}}async _parse(e){const n=await this.filehandle.readFile(e),r=await zr(n);let o;if(r.readUInt32LE(0)===oM)o=1;else if(r.readUInt32LE(0)===sM)o=2;else throw new Error("Not a CSI file");this.minShift=r.readInt32LE(4),this.depth=r.readInt32LE(8),this.maxBinNumber=((1<<(this.depth+1)*3)-1)/7;const i=r.readInt32LE(12),s=i>=30?this.parseAuxData(r,16):void 0,a=r.readInt32LE(16+i);let c=16+i+4,l;const u=new Array(a);for(let f=0;f<a;f++){const d=r.readInt32LE(c);c+=4;const h={};let p;for(let y=0;y<d;y++){const v=r.readUInt32LE(c);if(c+=4,v>this.maxBinNumber)p=Tx(r,c+28),c+=44;else{l=hu(l,Ro(r,c)),c+=8;const b=r.readInt32LE(c);c+=4;const A=new Array(b);for(let S=0;S<b;S+=1){const E=Ro(r,c);c+=8;const I=Ro(r,c);c+=8,l=hu(l,E),A[S]=new a0(E,I,v)}h[v]=A}}u[f]={binIndex:h,stats:p}}return{csiVersion:o,firstDataLine:l,indices:u,refCount:a,csi:!0,maxBlockSize:65536,...s}}async blocksForRange(e,n,r,o={}){n<0&&(n=0);const s=(await this.parse(o)).indices[e];if(!s)return[];const a=this.reg2bins(n,r);if(a.length===0)return[];const c=[];for(const[l,u]of a)for(let f=l;f<=u;f++)if(s.binIndex[f]){const d=s.binIndex[f];for(const h of d)c.push(h)}return Ix(c,new Cx(0,0))}reg2bins(e,n){e-=1,e<1&&(e=1),n>2**50&&(n=2**34),n-=1;let r=0,o=0,i=this.minShift+this.depth*3;const s=[];for(;r<=this.depth;i-=3,o+=aM(1,r*3),r+=1){const a=o+kx(e,i),c=o+kx(n,i);if(c-a+s.length>this.maxBinNumber)throw new Error(`query ${e}-${n} is too large for current binning scheme (shift ${this.minShift}, depth ${this.depth}), try a smaller query or a coarser index binning scheme`);s.push([a,c])}return s}async parse(e={}){return this.setupP||(this.setupP=this._parse(e).catch(n=>{throw this.setupP=void 0,n})),this.setupP}async hasRefSeq(e,n={}){var r;return!!(!((r=(await this.parse(n)).indices[e])===null||r===void 0)&&r.binIndex)}};const pn={BAM_FPAIRED:1,BAM_FPROPER_PAIR:2,BAM_FUNMAP:4,BAM_FMUNMAP:8,BAM_FREVERSE:16,BAM_FMREVERSE:32,BAM_FREAD1:64,BAM_FREAD2:128,BAM_FSECONDARY:256,BAM_FQCFAIL:512,BAM_FDUP:1024,BAM_FSUPPLEMENTARY:2048},_x="=ACMGRSVTWYHKDBN".split(""),Oa="MIDNSHP=X???????".split("");class Mo{constructor(e){this.bytes=e.bytes,this.fileOffset=e.fileOffset}get byteArray(){return this.bytes.byteArray}get flags(){return(this.byteArray.readInt32LE(this.bytes.start+16)&4294901760)>>16}get ref_id(){return this.byteArray.readInt32LE(this.bytes.start+4)}get start(){return this.byteArray.readInt32LE(this.bytes.start+8)}get end(){return this.start+this.length_on_ref}get id(){return this.fileOffset}get mq(){const e=(this.bin_mq_nl&65280)>>8;return e===255?void 0:e}get score(){return this.mq}get qual(){if(this.isSegmentUnmapped())return;const e=this.b0+this.read_name_length+this.num_cigar_ops*4+this.num_seq_bytes;return this.byteArray.subarray(e,e+this.seq_length)}get strand(){return this.isReverseComplemented()?-1:1}get b0(){return this.bytes.start+36}get name(){return this.byteArray.toString("ascii",this.b0,this.b0+this.read_name_length-1)}get tags(){const{byteArray:e}=this.bytes;let n=this.b0+this.read_name_length+this.num_cigar_ops*4+this.num_seq_bytes+this.seq_length;const r=this.bytes.end,o={};for(;n<r;){const i=String.fromCharCode(e[n],e[n+1]),s=String.fromCharCode(e[n+2]);if(n+=3,s==="A")o[i]=String.fromCharCode(e[n]),n+=1;else if(s==="i")o[i]=e.readInt32LE(n),n+=4;else if(s==="I")o[i]=e.readUInt32LE(n),n+=4;else if(s==="c")o[i]=e.readInt8(n),n+=1;else if(s==="C")o[i]=e.readUInt8(n),n+=1;else if(s==="s")o[i]=e.readInt16LE(n),n+=2;else if(s==="S")o[i]=e.readUInt16LE(n),n+=2;else if(s==="f")o[i]=e.readFloatLE(n),n+=4;else if(s==="Z"||s==="H"){const a=[];for(;n<=r;){const c=e[n++];if(c!==0)a.push(String.fromCharCode(c));else break}o[i]=a.join("")}else if(s==="B"){const a=e[n++],c=String.fromCharCode(a),l=e.readInt32LE(n);if(n+=4,c==="i")if(i==="CG"){const u=[];for(let f=0;f<l;f++){const d=e.readInt32LE(n),h=d>>4,p=Oa[d&15];u.push(h+p),n+=4}o[i]=u.join("")}else{const u=[];for(let f=0;f<l;f++)u.push(e.readInt32LE(n)),n+=4;o[i]=u}else if(c==="I")if(i==="CG"){const u=[];for(let f=0;f<l;f++){const d=e.readUInt32LE(n),h=d>>4,p=Oa[d&15];u.push(h+p),n+=4}o[i]=u.join("")}else{const u=[];for(let f=0;f<l;f++)u.push(e.readUInt32LE(n)),n+=4;o[i]=u}else if(c==="s"){const u=[];for(let f=0;f<l;f++)u.push(e.readInt16LE(n)),n+=2;o[i]=u}else if(c==="S"){const u=[];for(let f=0;f<l;f++)u.push(e.readUInt16LE(n)),n+=2;o[i]=u}else if(c==="c"){const u=[];for(let f=0;f<l;f++)u.push(e.readInt8(n)),n+=1;o[i]=u}else if(c==="C"){const u=[];for(let f=0;f<l;f++)u.push(e.readUInt8(n)),n+=1;o[i]=u}else if(c==="f"){const u=[];for(let f=0;f<l;f++)u.push(e.readFloatLE(n)),n+=4;o[i]=u}}else{console.error("Unknown BAM tag type",s);break}}return o}isPaired(){return!!(this.flags&pn.BAM_FPAIRED)}isProperlyPaired(){return!!(this.flags&pn.BAM_FPROPER_PAIR)}isSegmentUnmapped(){return!!(this.flags&pn.BAM_FUNMAP)}isMateUnmapped(){return!!(this.flags&pn.BAM_FMUNMAP)}isReverseComplemented(){return!!(this.flags&pn.BAM_FREVERSE)}isMateReverseComplemented(){return!!(this.flags&pn.BAM_FMREVERSE)}isRead1(){return!!(this.flags&pn.BAM_FREAD1)}isRead2(){return!!(this.flags&pn.BAM_FREAD2)}isSecondary(){return!!(this.flags&pn.BAM_FSECONDARY)}isFailedQc(){return!!(this.flags&pn.BAM_FQCFAIL)}isDuplicate(){return!!(this.flags&pn.BAM_FDUP)}isSupplementary(){return!!(this.flags&pn.BAM_FSUPPLEMENTARY)}get cigarAndLength(){if(this.isSegmentUnmapped())return{length_on_ref:0,CIGAR:""};const e=this.num_cigar_ops;let n=this.b0+this.read_name_length;const r=[];let o=this.byteArray.readInt32LE(n),i=o>>4,s=Oa[o&15];if(s==="S"&&i===this.seq_length)return n+=4,o=this.byteArray.readInt32LE(n),i=o>>4,s=Oa[o&15],s!=="N"&&console.warn("CG tag with no N tag"),{CIGAR:this.tags.CG,length_on_ref:i};{let a=0;for(let c=0;c<e;++c)o=this.byteArray.readInt32LE(n),i=o>>4,s=Oa[o&15],r.push(i+s),s!=="H"&&s!=="S"&&s!=="I"&&(a+=i),n+=4;return{CIGAR:r.join(""),length_on_ref:a}}}get length_on_ref(){return this.cigarAndLength.length_on_ref}get CIGAR(){return this.cigarAndLength.CIGAR}get num_cigar_ops(){return this.flag_nc&65535}get read_name_length(){return this.bin_mq_nl&255}get num_seq_bytes(){return this.seq_length+1>>1}get seq(){const{byteArray:e}=this.bytes,n=this.b0+this.read_name_length+this.num_cigar_ops*4,r=this.num_seq_bytes,o=this.seq_length,i=[];let s=0;for(let a=0;a<r;++a){const c=e[n+a];i.push(_x[(c&240)>>4]),s++,s<o&&(i.push(_x[c&15]),s++)}return i.join("")}get pair_orientation(){if(!this.isSegmentUnmapped()&&!this.isMateUnmapped()&&this.ref_id===this.next_refid){const e=this.isReverseComplemented()?"R":"F",n=this.isMateReverseComplemented()?"R":"F";let r=" ",o=" ";this.isRead1()?(r="1",o="2"):this.isRead2()&&(r="2",o="1");const i=[];return this.template_length>0?(i[0]=e,i[1]=r,i[2]=n,i[3]=o):(i[2]=e,i[3]=r,i[0]=n,i[1]=o),i.join("")}}get bin_mq_nl(){return this.byteArray.readInt32LE(this.bytes.start+12)}get flag_nc(){return this.byteArray.readInt32LE(this.bytes.start+16)}get seq_length(){return this.byteArray.readInt32LE(this.bytes.start+20)}get next_refid(){return this.byteArray.readInt32LE(this.bytes.start+24)}get next_pos(){return this.byteArray.readInt32LE(this.bytes.start+28)}get template_length(){return this.byteArray.readInt32LE(this.bytes.start+32)}toJSON(){const e={};for(const n of Object.keys(this))n.startsWith("_")||n==="bytes"||(e[n]=this[n]);return e}}function pu(t,e){const n=Object.getOwnPropertyDescriptor(t.prototype,e);if(!n)throw new Error("OH NO, NO PROPERTY DESCRIPTOR");const r=n.get;if(!r)throw new Error("OH NO, NOT A GETTER");Object.defineProperty(t.prototype,e,{get(){const o=r.call(this);return Object.defineProperty(this,e,{value:o}),o}})}pu(Mo,"tags"),pu(Mo,"cigarAndLength"),pu(Mo,"seq"),pu(Mo,"qual");function Rx(t){const e=t.split(/\r?\n/),n=[];for(const r of e){const[o,...i]=r.split(/\t/);o&&n.push({tag:o.slice(1),data:i.map(s=>{const a=s.indexOf(":"),c=s.slice(0,a),l=s.slice(a+1);return{tag:c,value:l}})})}return n}const Fx=21840194,Mx=65536;async function cM(t){let e=[];for await(const n of t)e=e.concat(n);return e}class lM{read(){throw new Error("never called")}stat(){throw new Error("never called")}readFile(){throw new Error("never called")}close(){throw new Error("never called")}}class Px{constructor({bamFilehandle:e,bamPath:n,bamUrl:r,baiPath:o,baiFilehandle:i,baiUrl:s,csiPath:a,csiFilehandle:c,csiUrl:l,htsget:u,yieldThreadTime:f=100,renameRefSeqs:d=h=>h}){if(this.htsget=!1,this.featureCache=new Di({cache:new tu({maxSize:50}),fill:async(h,p)=>{const{chunk:y,opts:v}=h,{data:b,cpositions:A,dpositions:S}=await this._readChunk({chunk:y,opts:{...v,signal:p}});return this.readBamFeatures(b,A,S,y)}}),this.renameRefSeq=d,e)this.bam=e;else if(n)this.bam=new Ct(n);else if(r)this.bam=new Cn(r);else if(u)this.htsget=!0,this.bam=new lM;else throw new Error("unable to initialize bam");if(c)this.index=new du({filehandle:c});else if(a)this.index=new du({filehandle:new Ct(a)});else if(l)this.index=new du({filehandle:new Cn(l)});else if(i)this.index=new Fo({filehandle:i});else if(o)this.index=new Fo({filehandle:new Ct(o)});else if(s)this.index=new Fo({filehandle:new Cn(s)});else if(n)this.index=new Fo({filehandle:new Ct(`${n}.bai`)});else if(r)this.index=new Fo({filehandle:new Cn(`${r}.bai`)});else if(u)this.htsget=!0;else throw new Error("unable to infer index format");this.yieldThreadTime=f}async getHeaderPre(e){const n=X9(e);if(!this.index)return;const r=await this.index.parse(n),o=r.firstDataLine?r.firstDataLine.blockPosition+65535:void 0;let i;if(o){const u=o+Mx,f=await this.bam.read(Ke.Buffer.alloc(u),0,u,0,n);if(!f.bytesRead)throw new Error("Error reading header");i=f.buffer.subarray(0,Math.min(f.bytesRead,o))}else i=await this.bam.readFile(n);const s=await zr(i);if(s.readInt32LE(0)!==Fx)throw new Error("Not a BAM file");const a=s.readInt32LE(4);this.header=s.toString("utf8",8,8+a);const{chrToIndex:c,indexToChr:l}=await this._readRefSeqs(a+8,65535,n);return this.chrToIndex=c,this.indexToChr=l,Rx(this.header)}getHeader(e){return this.headerP||(this.headerP=this.getHeaderPre(e).catch(n=>{throw this.headerP=void 0,n})),this.headerP}async getHeaderText(e={}){return await this.getHeader(e),this.header}async _readRefSeqs(e,n,r){if(e>n)return this._readRefSeqs(e,n*2,r);const o=n+Mx,{bytesRead:i,buffer:s}=await this.bam.read(Ke.Buffer.alloc(o),0,n,0,r);if(!i)throw new Error("Error reading refseqs from header");const a=await zr(s.subarray(0,Math.min(i,n))),c=a.readInt32LE(e);let l=e+4;const u={},f=[];for(let d=0;d<c;d+=1){const h=a.readInt32LE(l),p=this.renameRefSeq(a.toString("utf8",l+4,l+4+h-1)),y=a.readInt32LE(l+h+4);if(u[p]=d,f.push({refName:p,length:y}),l=l+8+h,l>a.length)return console.warn(`BAM header is very big.  Re-fetching ${n} bytes.`),this._readRefSeqs(e,n*2,r)}return{chrToIndex:u,indexToChr:f}}async getRecordsForRange(e,n,r,o){return cM(this.streamRecordsForRange(e,n,r,o))}async*streamRecordsForRange(e,n,r,o){var i;await this.getHeader(o);const s=(i=this.chrToIndex)===null||i===void 0?void 0:i[e];if(s===void 0||!this.index)yield[];else{const a=await this.index.blocksForRange(s,n-1,r,o);yield*this._fetchChunkFeatures(a,s,n,r,o)}}async*_fetchChunkFeatures(e,n,r,o,i={}){const{viewAsPairs:s}=i,a=[];let c=!1;for(const l of e){const u=await this.featureCache.get(l.toString(),{chunk:l,opts:i},i.signal),f=[];for(const d of u)if(d.ref_id===n)if(d.start>=o){c=!0;break}else d.end>=r&&f.push(d);if(a.push(f),yield f,c)break}Q9(i.signal),s&&(yield this.fetchPairs(n,a,i))}async fetchPairs(e,n,r){const{pairAcrossChr:o,maxInsertSize:i=2e5}=r,s={},a={};n.map(d=>{const h={};for(const p of d){const y=p.name,v=p.id;h[y]||(h[y]=0),h[y]++,a[v]=1}for(const[p,y]of Object.entries(h))y===1&&(s[p]=!0)});const c=[];n.map(d=>{for(const h of d){const p=h.name,y=h.start,v=h.next_pos,b=h.next_refid;this.index&&s[p]&&(o||b===e&&Math.abs(y-v)<i)&&c.push(this.index.blocksForRange(b,v,v+1,r))}});const l=new Map,u=await Promise.all(c);for(const d of u.flat())l.has(d.toString())||l.set(d.toString(),d);return(await Promise.all([...l.values()].map(async d=>{const{data:h,cpositions:p,dpositions:y,chunk:v}=await this._readChunk({chunk:d,opts:r}),b=[];for(const A of await this.readBamFeatures(h,p,y,v))s[A.name]&&!a[A.id]&&b.push(A);return b}))).flat()}async _readRegion(e,n,r={}){const{bytesRead:o,buffer:i}=await this.bam.read(Ke.Buffer.alloc(n),0,n,e,r);return i.subarray(0,Math.min(o,n))}async _readChunk({chunk:e,opts:n}){const r=await this._readRegion(e.minv.blockPosition,e.fetchedSize(),n),{buffer:o,cpositions:i,dpositions:s}=await q2(r,e);return{data:o,cpositions:i,dpositions:s,chunk:e}}async readBamFeatures(e,n,r,o){let i=0;const s=[];let a=0,c=+Date.now();for(;i+4<e.length;){const l=e.readInt32LE(i),u=i+4+l-1;if(r){for(;i+o.minv.dataPosition>=r[a++];);a--}if(u<e.length){const f=new Mo({bytes:{byteArray:e,start:i,end:u},fileOffset:n.length>0?n[a]*256+(i-r[a])+o.minv.dataPosition+1:iM.signed(e.slice(i,u))});s.push(f),this.yieldThreadTime&&+Date.now()-c>this.yieldThreadTime&&(await Y9(1),c=+Date.now())}i=u+1}return s}async hasRefSeq(e){var n,r;const o=(n=this.chrToIndex)===null||n===void 0?void 0:n[e];return o===void 0?!1:(r=this.index)===null||r===void 0?void 0:r.hasRefSeq(o)}async lineCount(e){var n;const r=(n=this.chrToIndex)===null||n===void 0?void 0:n[e];return r===void 0||!this.index?0:this.index.lineCount(r)}async indexCov(e,n,r){var o;if(!this.index)return[];await this.index.parse();const i=(o=this.chrToIndex)===null||o===void 0?void 0:o[e];return i===void 0?[]:this.index.indexCov(i,n,r)}async blocksForRange(e,n,r,o){var i;if(!this.index)return[];await this.index.parse();const s=(i=this.chrToIndex)===null||i===void 0?void 0:i[e];return s===void 0?[]:this.index.blocksForRange(s,n,r,o)}}async function Lx(t,e){const n=await Promise.all(t.map(async r=>{const{url:o,headers:i}=r;if(o.startsWith("data:"))return Ke.Buffer.from(o.split(",")[1],"base64");{const{referer:s,...a}=i,c=await fetch(o,{...e,headers:{...e==null?void 0:e.headers,...a}});if(!c.ok)throw new Error(`HTTP ${c.status} fetching ${o}: ${await c.text()}`);return Ke.Buffer.from(await c.arrayBuffer())}}));return Ke.Buffer.concat(await Promise.all(n.map(r=>zr(r))))}class uM extends Px{constructor(e){super({htsget:!0}),this.baseUrl=e.baseUrl,this.trackId=e.trackId}async*streamRecordsForRange(e,n,r,o){var i;const a=`${`${this.baseUrl}/${this.trackId}`}?referenceName=${e}&start=${n}&end=${r}&format=BAM`,c=(i=this.chrToIndex)===null||i===void 0?void 0:i[e];if(c===void 0)yield[];else{const l=await fetch(a,{...o});if(!l.ok)throw new Error(`HTTP ${l.status} fetching ${a}: ${await l.text()}`);const u=await l.json(),f=await Lx(u.htsget.urls.slice(1),o);yield*this._fetchChunkFeatures([{buffer:f,_fetchedSize:void 0,bin:0,compareTo(){return 0},toUniqueString(){return`${e}_${n}_${r}`},fetchedSize(){return 0},minv:{dataPosition:0,blockPosition:0,compareTo:()=>0},maxv:{dataPosition:Number.MAX_SAFE_INTEGER,blockPosition:0,compareTo:()=>0},toString(){return`${e}_${n}_${r}`}}],c,n,r,o)}}async _readChunk({chunk:e}){if(!e.buffer)throw new Error("expected chunk.buffer in htsget");return{data:e.buffer,cpositions:[],dpositions:[],chunk:e}}async getHeader(e={}){const n=`${this.baseUrl}/${this.trackId}?referenceName=na&class=header`,r=await fetch(n,e);if(!r.ok)throw new Error(`HTTP ${r.status} fetching ${n}: ${await r.text()}`);const o=await r.json(),i=await Lx(o.htsget.urls,e);if(i.readInt32LE(0)!==Fx)throw new Error("Not a BAM file");const s=i.readInt32LE(4),a=i.toString("utf8",8,8+s),c=Rx(a),l=[],u={},f=c.filter(d=>d.tag==="SQ");for(const[d,h]of f.entries()){let p="",y=0;for(const v of h.data)v.tag==="SN"?p=v.value:v.tag==="LN"&&(y=+v.value);u[p]=d,l[d]={refName:p,length:y}}return this.chrToIndex=u,this.indexToChr=l,c}}const fM=Object.freeze(Object.defineProperty({__proto__:null,BAI:Fo,BamFile:Px,BamRecord:Mo,CSI:du,HtsgetFile:uM},Symbol.toStringTag,{value:"Module"}));function Ox(t){if(t.greaterThan(Number.MAX_SAFE_INTEGER)||t.lessThan(Number.MIN_SAFE_INTEGER))throw new Error("integer overflow");return t.toNumber()}class hM extends Error{}function Na(t){if(t&&t.aborted){if(typeof DOMException<"u")throw new DOMException("aborted","AbortError");{const e=new hM("aborted");throw e.code="ERR_ABORTED",e}}}function dM(t,e){return e.minv.blockPosition-t.maxv.blockPosition<65e3&&e.maxv.blockPosition-t.minv.blockPosition<5e6}function Nx(t,e){const n=[];let r=null;return t.length===0?t:(t.sort(function(o,i){const s=o.minv.blockPosition-i.minv.blockPosition;return s!==0?s:o.minv.dataPosition-i.minv.dataPosition}),t.forEach(o=>{(!e||o.maxv.compareTo(e)>0)&&(r===null?(n.push(o),r=o):dM(r,o)?o.maxv.compareTo(r.maxv)>0&&(r.maxv=o.maxv):(n.push(o),r=o))}),n)}class l0{constructor(e,n){this.blockPosition=e,this.dataPosition=n}toString(){return`${this.blockPosition}:${this.dataPosition}`}compareTo(e){return this.blockPosition-e.blockPosition||this.dataPosition-e.dataPosition}}function Po(t,e=0,n=!1){if(n)throw new Error("big-endian virtual file offsets not implemented");return new l0(t[e+7]*1099511627776+t[e+6]*4294967296+t[e+5]*16777216+t[e+4]*65536+t[e+3]*256+t[e+2],t[e+1]<<8|t[e])}class gu{constructor(e,n,r,o=void 0){this.minv=e,this.maxv=n,this.bin=r,this._fetchedSize=o}toUniqueString(){return`${this.minv}..${this.maxv} (bin ${this.bin}, fetchedSize ${this.fetchedSize()})`}toString(){return this.toUniqueString()}compareTo(e){return this.minv.compareTo(e.minv)||this.maxv.compareTo(e.maxv)||this.bin-e.bin}fetchedSize(){return this._fetchedSize!==void 0?this._fetchedSize:this.maxv.blockPosition+65536-this.minv.blockPosition}}class zx{constructor({filehandle:e,renameRefSeqs:n=r=>r}){this.filehandle=e,this.renameRefSeq=n}async getMetadata(e={}){const{indices:n,...r}=await this.parse(e);return r}_findFirstData(e,n){return e?e.compareTo(n)>0?n:e:n}async parse(e={}){return this.parseP||(this.parseP=this._parse(e).catch(n=>{throw this.parseP=void 0,n})),this.parseP}async hasRefSeq(e,n={}){var r;return!!(!((r=(await this.parse(n)).indices[e])===null||r===void 0)&&r.binIndex)}}const pM=21578324,Ux=14;function gM(t,e){return t+=1,e-=1,[[0,0],[1+(t>>26),1+(e>>26)],[9+(t>>23),9+(e>>23)],[73+(t>>20),73+(e>>20)],[585+(t>>17),585+(e>>17)],[4681+(t>>14),4681+(e>>14)]]}class Lo extends zx{async lineCount(e,n={}){const r=await this.parse(n),o=r.refNameToId[e];if(o===void 0||!r.indices[o])return-1;const{stats:s}=r.indices[o];return s?s.lineCount:-1}async _parse(e={}){const n=await this.filehandle.readFile(e),r=await zr(n);if(Na(e.signal),r.readUInt32LE(0)!==pM)throw new Error("Not a TBI file");const o=r.readInt32LE(4),i=r.readInt32LE(8),s=i&65536?"zero-based-half-open":"1-based-closed",c={0:"generic",1:"SAM",2:"VCF"}[i&15];if(!c)throw new Error(`invalid Tabix preset format flags ${i}`);const l={ref:r.readInt32LE(12),start:r.readInt32LE(16),end:r.readInt32LE(20)},u=r.readInt32LE(24),f=5,d=((1<<(f+1)*3)-1)/7,h=2**(14+f*3),p=u?String.fromCharCode(u):null,y=r.readInt32LE(28),v=r.readInt32LE(32),{refNameToId:b,refIdToName:A}=this._parseNameBytes(r.slice(36,36+v));let S=36+v,E;return{indices:new Array(o).fill(0).map(()=>{const _=r.readInt32LE(S);S+=4;const B={};let N;for(let C=0;C<_;C+=1){const Y=r.readUInt32LE(S);if(S+=4,Y>d+1)throw new Error("tabix index contains too many bins, please use a CSI index");if(Y===d+1){const Q=r.readInt32LE(S);S+=4,Q===2&&(N=this.parsePseudoBin(r,S)),S+=16*Q}else{const Q=r.readInt32LE(S);S+=4;const oe=new Array(Q);for(let se=0;se<Q;se+=1){const ae=Po(r,S),ce=Po(r,S+8);S+=16,E=this._findFirstData(E,ae),oe[se]=new gu(ae,ce,Y)}B[Y]=oe}}const F=r.readInt32LE(S);S+=4;const M=new Array(F);for(let C=0;C<F;C+=1)M[C]=Po(r,S),S+=8,E=this._findFirstData(E,M[C]);return{binIndex:B,linearIndex:M,stats:N}}),metaChar:p,maxBinNumber:d,maxRefLength:h,skipLines:y,firstDataLine:E,columnNumbers:l,coordinateType:s,format:c,refIdToName:A,refNameToId:b,maxBlockSize:65536}}parsePseudoBin(e,n){return{lineCount:Ox($l.fromBytesLE(e.slice(n+16,n+24),!0))}}_parseNameBytes(e){let n=0,r=0;const o=[],i={};for(let s=0;s<e.length;s+=1)if(!e[s]){if(r<s){let a=e.toString("utf8",r,s);a=this.renameRefSeq(a),o[n]=a,i[a]=n}r=s+1,n+=1}return{refNameToId:i,refIdToName:o}}async blocksForRange(e,n,r,o={}){n<0&&(n=0);const i=await this.parse(o),s=i.refNameToId[e];if(s===void 0)return[];const a=i.indices[s];if(!a)return[];(a.linearIndex.length?a.linearIndex[n>>Ux>=a.linearIndex.length?a.linearIndex.length-1:n>>Ux]:new l0(0,0))||console.warn("querying outside of possible tabix range");const l=gM(n,r),u=[];for(const[y,v]of l)for(let b=y;b<=v;b++)if(a.binIndex[b])for(const A of a.binIndex[b])u.push(new gu(A.minv,A.maxv,b));const f=a.linearIndex.length;let d=null;const h=Math.min(n>>14,f-1),p=Math.min(r>>14,f-1);for(let y=h;y<=p;++y){const v=a.linearIndex[y];v&&(!d||v.compareTo(d)<0)&&(d=v)}return Nx(u,d)}}const mM=21582659,yM=38359875;function bM(t,e){return t*2**e}function Gx(t,e){return Math.floor(t/2**e)}class mu extends zx{constructor(e){super(e),this.maxBinNumber=0,this.depth=0,this.minShift=0}async lineCount(e,n={}){const r=await this.parse(n),o=r.refNameToId[e];if(o===void 0||!r.indices[o])return-1;const{stats:s}=r.indices[o];return s?s.lineCount:-1}indexCov(){throw new Error("CSI indexes do not support indexcov")}parseAuxData(e,n){const r=e.readInt32LE(n),o=r&65536?"zero-based-half-open":"1-based-closed",i={0:"generic",1:"SAM",2:"VCF"}[r&15];if(!i)throw new Error(`invalid Tabix preset format flags ${r}`);const s={ref:e.readInt32LE(n+4),start:e.readInt32LE(n+8),end:e.readInt32LE(n+12)},a=e.readInt32LE(n+16),c=a?String.fromCharCode(a):null,l=e.readInt32LE(n+20),u=e.readInt32LE(n+24),{refIdToName:f,refNameToId:d}=this._parseNameBytes(e.slice(n+28,n+28+u));return{refIdToName:f,refNameToId:d,skipLines:l,metaChar:c,columnNumbers:s,format:i,coordinateType:o}}_parseNameBytes(e){let n=0,r=0;const o=[],i={};for(let s=0;s<e.length;s+=1)if(!e[s]){if(r<s){let a=e.toString("utf8",r,s);a=this.renameRefSeq(a),o[n]=a,i[a]=n}r=s+1,n+=1}return{refNameToId:i,refIdToName:o}}async _parse(e={}){const n=await zr(await this.filehandle.readFile(e));let r;if(n.readUInt32LE(0)===mM)r=1;else if(n.readUInt32LE(0)===yM)r=2;else throw new Error("Not a CSI file");this.minShift=n.readInt32LE(4),this.depth=n.readInt32LE(8),this.maxBinNumber=((1<<(this.depth+1)*3)-1)/7;const o=2**(this.minShift+this.depth*3),i=n.readInt32LE(12),s=i&&i>=30?this.parseAuxData(n,16):{refIdToName:[],refNameToId:{},metaChar:null,columnNumbers:{ref:0,start:1,end:2},coordinateType:"zero-based-half-open",format:"generic"},a=n.readInt32LE(16+i);let c,l=16+i+4;const u=new Array(a).fill(0).map(()=>{const f=n.readInt32LE(l);l+=4;const d={};let h;for(let p=0;p<f;p+=1){const y=n.readUInt32LE(l);if(y>this.maxBinNumber)h=this.parsePseudoBin(n,l+4),l+=48;else{const v=Po(n,l+4);c=this._findFirstData(c,v);const b=n.readInt32LE(l+12);l+=16;const A=new Array(b);for(let S=0;S<b;S+=1){const E=Po(n,l),I=Po(n,l+8);l+=16,A[S]=new gu(E,I,y)}d[y]=A}}return{binIndex:d,stats:h}});return{...s,csi:!0,refCount:a,maxBlockSize:65536,firstDataLine:c,csiVersion:r,indices:u,depth:this.depth,maxBinNumber:this.maxBinNumber,maxRefLength:o}}parsePseudoBin(e,n){return{lineCount:Ox($l.fromBytesLE(e.slice(n+28,n+36),!0))}}async blocksForRange(e,n,r,o={}){n<0&&(n=0);const i=await this.parse(o),s=i.refNameToId[e];if(s===void 0)return[];const a=i.indices[s];if(!a)return[];const c=this.reg2bins(n,r),l=[];for(const[u,f]of c)for(let d=u;d<=f;d++)if(a.binIndex[d])for(const h of a.binIndex[d])l.push(new gu(h.minv,h.maxv,d));return Nx(l,new l0(0,0))}reg2bins(e,n){e-=1,e<1&&(e=1),n>2**50&&(n=2**34),n-=1;let r=0,o=0,i=this.minShift+this.depth*3;const s=[];for(;r<=this.depth;i-=3,o+=bM(1,r*3),r+=1){const a=o+Gx(e,i),c=o+Gx(n,i);if(c-a+s.length>this.maxBinNumber)throw new Error(`query ${e}-${n} is too large for current binning scheme (shift ${this.minShift}, depth ${this.depth}), try a smaller query or a coarser index binning scheme`);s.push([a,c])}return s}}function wM(t){return/^[\u0000-\u007F]*$/.test(t)}const Oo=typeof TextDecoder<"u"?new TextDecoder("utf8"):void 0;class xM{constructor({path:e,filehandle:n,url:r,tbiPath:o,tbiUrl:i,tbiFilehandle:s,csiPath:a,csiUrl:c,csiFilehandle:l,renameRefSeqs:u=d=>d,chunkCacheSize:f=5*2**20}){if(n)this.filehandle=n;else 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d(){i.removeListener("data",s),r.removeListener("drain",a),i.removeListener("end",l),i.removeListener("close",u),i.removeListener("error",f),r.removeListener("error",f),i.removeListener("end",d),i.removeListener("close",d),r.removeListener("close",d)}return i.on("end",d),i.on("close",d),r.on("close",d),r.emit("pipe",i),r},B0}var gv=BM(),kM=x0();function za(t){return t.replace(/%([0-9A-Fa-f]{2})/g,(e,n)=>String.fromCharCode(parseInt(n,16)))}function mv(t,e){return String(e).replace(t,n=>`%${n.charCodeAt(0).toString(16).toUpperCase().padStart(2,"0")}`)}function Ua(t){return mv(/[\n;\r\t=%&,\x00-\x1f\x7f-\xff]/g,t)}function or(t){return mv(/[\n\r\t%\x00-\x1f\x7f-\xff]/g,t)}function yv(t){if(!(t&&t.length)||t===".")return{};const e={};return t.replace(/\r?\n$/,"").split(";").forEach(n=>{const r=n.split("=",2);if(!(r[1]&&r[1].length))return;r[0]=r[0].trim();let o=e[r[0].trim()];o||(o=[],e[r[0]]=o),o.push(...r[1].split(",").map(i=>i.trim()).map(za))}),e}function bv(t){const e=t.split("	").map(r=>r==="."||r===""?null:r);return{seq_id:e[0]&&za(e[0]),source:e[1]&&za(e[1]),type:e[2]&&za(e[2]),start:e[3]===null?null:parseInt(e[3],10),end:e[4]===null?null:parseInt(e[4],10),score:e[5]===null?null:parseFloat(e[5]),strand:e[6],phase:e[7],attributes:e[8]===null?null:yv(e[8])}}function wv(t){const e=/^\s*##\s*(\S+)\s*(.*)/.exec(t);if(!e)return null;const[,n]=e;let[,,r]=e;const o={directive:n};if(r.length&&(r=r.replace(/\r?\n$/,""),o.value=r),n==="sequence-region"){const i=r.split(/\s+/,3);return{...o,seq_id:i[0],start:i[1]&&i[1].replace(/\D/g,""),end:i[2]&&i[2].replace(/\D/g,"")}}else if(n==="genome-build"){const[i,s]=r.split(/\s+/,2);return{...o,source:i,buildName:s}}return o}function xv(t){const e=[];return Object.entries(t).forEach(([n,r])=>{if(!r)return;let o;r.hasOwnProperty("toString")?o=Ua(r.toString()):Array.isArray(r)?o=r.map(Ua).join(","):o=Ua(r),e.push(`${Ua(n)}=${o}`)}),e.length?e.join(";"):"."}function _M(t,e){const n=t.attributes===null||t.attributes===void 0?".":xv(t.attributes),o=`${[t.seq_id===null?".":or(t.seq_id),t.source===null?".":or(t.source),t.type===null?".":or(t.type),t.start===null?".":or(t.start),t.end===null?".":or(t.end),t.score===null?".":or(t.score),t.strand===null?".":or(t.strand),t.phase===null?".":or(t.phase),n].join("	")}
-`;return e[o]?"":(e[o]=!0,o)}function xu(t,e){if(Array.isArray(t))return t.map(r=>xu(r,e)).join("");const n=[_M(t,e)];return RM(t)&&n.push(...t.child_features.map(r=>xu(r,e)),...t.derived_features.map(r=>xu(r,e))),n.join("")}function vv(t){return xu(t,{})}function Av(t){let e=`##${t.directive}`;return t.value&&(e+=` ${t.value}`),e+=`
-`,e}function Ev(t){return`# ${t.comment}
-`}function k0(t){return`>${t.id}${t.description?` ${t.description}`:""}
-${t.sequence}
-`}function vu(t){function e(n){return"attributes"in n?vv(n):"directive"in n?Av(n):"sequence"in n?k0(n):"comment"in n?Ev(n):`# (invalid item found during format)
-`}return Array.isArray(t)?t.map(e):e(t)}function RM(t){return t.child_features!==void 0&&t.derived_features!==void 0}const FM=Object.freeze(Object.defineProperty({__proto__:null,escape:Ua,escapeColumn:or,formatAttributes:xv,formatComment:Ev,formatDirective:Av,formatFeature:vv,formatItem:vu,formatSequence:k0,parseAttributes:yv,parseDirective:wv,parseFeature:bv,unescape:za},Symbol.toStringTag,{value:"Module"})),Sv={Parent:"child_features",Derives_from:"derived_features"};class Cv{constructor(e){this.seqCallback=e,this.currentSequence=void 0}addLine(e){const n=/^>\s*(\S+)\s*(.*)/.exec(e);n?(this._flush(),this.currentSequence={id:n[1],sequence:""},n[2]&&(this.currentSequence.description=n[2].trim())):this.currentSequence&&/\S/.test(e)&&(this.currentSequence.sequence+=e.replace(/\s/g,""))}_flush(){this.currentSequence&&this.seqCallback(this.currentSequence)}finish(){this._flush()}}class Iv{constructor(e){this.fastaParser=void 0,this.eof=!1,this.lineNumber=0,this._underConstructionTopLevel=[],this._underConstructionById={},this._completedReferences={},this._underConstructionOrphans={};const n=()=>{};this.featureCallback=e.featureCallback||n,this.endCallback=e.endCallback||n,this.commentCallback=e.commentCallback||n,this.errorCallback=e.errorCallback||n,this.directiveCallback=e.directiveCallback||n,this.sequenceCallback=e.sequenceCallback||n,this.disableDerivesFromReferences=e.disableDerivesFromReferences||!1,this.bufferSize=e.bufferSize===void 0?1e3:e.bufferSize}addLine(e){if(this.fastaParser){this.fastaParser.addLine(e);return}if(this.eof)return;if(this.lineNumber+=1,/^\s*[^#\s>]/.test(e)){this._bufferLine(e);return}const n=/^\s*(#+)(.*)/.exec(e);if(n){const[,r]=n;let[,,o]=n;if(r.length===3)this._emitAllUnderConstructionFeatures();else if(r.length===2){const i=wv(e);i&&(i.directive==="FASTA"?(this._emitAllUnderConstructionFeatures(),this.eof=!0,this.fastaParser=new Cv(this.sequenceCallback)):this._emitItem(i))}else o=o.replace(/\s*/,""),this._emitItem({comment:o})}else if(!/^\s*$/.test(e))if(/^\s*>/.test(e))this._emitAllUnderConstructionFeatures(),this.eof=!0,this.fastaParser=new Cv(this.sequenceCallback),this.fastaParser.addLine(e);else{const r=e.replace(/\r?\n?$/g,"");throw new Error(`GFF3 parse error.  Cannot parse '${r}'.`)}}finish(){this._emitAllUnderConstructionFeatures(),this.fastaParser&&this.fastaParser.finish(),this.endCallback()}_emitItem(e){Array.isArray(e)?this.featureCallback(e):"directive"in e?this.directiveCallback(e):"comment"in e&&this.commentCallback(e)}_enforceBufferSizeLimit(e=0){const n=r=>{r&&Array.isArray(r)&&r[0].attributes&&r[0].attributes.ID&&r[0].attributes.ID[0]&&(r[0].attributes.ID.forEach(i=>{delete this._underConstructionById[i],delete this._completedReferences[i]}),r.forEach(i=>{i.child_features&&i.child_features.forEach(s=>n(s)),i.derived_features&&i.derived_features.forEach(s=>n(s))}))};for(;this._underConstructionTopLevel.length+e>this.bufferSize;){const r=this._underConstructionTopLevel.shift();r&&(this._emitItem(r),n(r))}}_emitAllUnderConstructionFeatures(){if(this._underConstructionTopLevel.forEach(this._emitItem.bind(this)),this._underConstructionTopLevel=[],this._underConstructionById={},this._completedReferences={},Array.from(Object.values(this._underConstructionOrphans)).length)throw new Error(`some features reference other features that do not exist in the file (or in the same '###' scope). ${Object.keys(this._underConstructionOrphans)}`)}_bufferLine(e){var n,r,o;const s={...bv(e),child_features:[],derived_features:[]},a=((n=s.attributes)===null||n===void 0?void 0:n.ID)||[],c=((r=s.attributes)===null||r===void 0?void 0:r.Parent)||[],l=this.disableDerivesFromReferences?[]:((o=s.attributes)===null||o===void 0?void 0:o.Derives_from)||[];if(!a.length&&!c.length&&!l.length){this._emitItem([s]);return}let u;a.forEach(f=>{const d=this._underConstructionById[f];d?(d[d.length-1].type!==s.type&&this._parseError(`multi-line feature "${f}" has inconsistent types: "${s.type}", "${d[d.length-1].type}"`),d.push(s),u=d):(u=[s],this._enforceBufferSizeLimit(1),!c.length&&!l.length&&this._underConstructionTopLevel.push(u),this._underConstructionById[f]=u,this._resolveReferencesTo(u,f))}),this._resolveReferencesFrom(u||[s],{Parent:c,Derives_from:l},a)}_resolveReferencesTo(e,n){const r=this._underConstructionOrphans[n];r&&(e.forEach(o=>{o.child_features.push(...r.Parent)}),e.forEach(o=>{o.derived_features.push(...r.Derives_from)}),delete this._underConstructionOrphans[n])}_parseError(e){this.eof=!0,this.errorCallback(`${this.lineNumber}: ${e}`)}_resolveReferencesFrom(e,n,r){function o(i,s,a){let c=i[s];c||(c={},i[s]=c);const l=c[a]||!1;return c[a]=!0,l}n.Parent.forEach(i=>{const s=this._underConstructionById[i];if(s){const a=Sv.Parent;r.filter(c=>o(this._completedReferences,c,`Parent,${i}`)).length||s.forEach(c=>{c[a].push(e)})}else{let a=this._underConstructionOrphans[i];a||(a={Parent:[],Derives_from:[]},this._underConstructionOrphans[i]=a),a.Parent.push(e)}}),n.Derives_from.forEach(i=>{const s=this._underConstructionById[i];if(s){const a=Sv.Derives_from;r.filter(c=>o(this._completedReferences,c,`Derives_from,${i}`)).length||s.forEach(c=>{c[a].push(e)})}else{let a=this._underConstructionOrphans[i];a||(a={Parent:[],Derives_from:[]},this._underConstructionOrphans[i]=a),a.Derives_from.push(e)}})}}function _0(t){process&&process.nextTick?process.nextTick(t):t()}function Tv(t){const e={encoding:"utf8",parseFeatures:!0,parseDirectives:!1,parseSequences:!0,parseComments:!1,bufferSize:1e3,disableDerivesFromReferences:!1,...t};return t.parseAll&&(e.parseFeatures=!0,e.parseDirectives=!0,e.parseComments=!0,e.parseSequences=!0),e}class MM extends gv.Transform{constructor(e={}){super({objectMode:!0}),this.textBuffer="";const n=Tv(e);this.encoding=e.encoding||"utf8",this.decoder=new kM.StringDecoder;const r=this.push.bind(this);this.parser=new Iv({featureCallback:n.parseFeatures?r:void 0,directiveCallback:n.parseDirectives?r:void 0,commentCallback:n.parseComments?r:void 0,sequenceCallback:n.parseSequences?r:void 0,errorCallback:o=>this.emit("error",o),bufferSize:n.bufferSize,disableDerivesFromReferences:n.disableDerivesFromReferences})}_addLine(e){e&&this.parser.addLine(e)}_nextText(e){const n=(this.textBuffer+e).split(/\r?\n/);this.textBuffer=n.pop()||"",n.forEach(r=>this._addLine(r))}_transform(e,n,r){this._nextText(this.decoder.write(e)),_0(r)}_flush(e){this.decoder.end&&this._nextText(this.decoder.end()),this.textBuffer!=null&&this._addLine(this.textBuffer),this.parser.finish(),_0(e)}}function PM(t={}){return new MM(t)}function LM(t,e={}){if(!t)return[];const n=Tv(e),r=[],o=r.push.bind(r),i=new Iv({featureCallback:n.parseFeatures?o:void 0,directiveCallback:n.parseDirectives?o:void 0,commentCallback:n.parseComments?o:void 0,sequenceCallback:n.parseSequences?o:void 0,disableDerivesFromReferences:n.disableDerivesFromReferences||!1,bufferSize:1/0,errorCallback:s=>{throw s}});return t.split(/\r?\n/).forEach(i.addLine.bind(i)),i.finish(),r}function OM(t){const e=[],n=[];t.forEach(o=>{"sequence"in o?n.push(o):e.push(o)});let r=e.map(vu).join("");return n.length&&(r+=`##FASTA
-`,r+=n.map(k0).join("")),r}class Dv extends gv.Transform{constructor(e={}){super(Object.assign(e,{objectMode:!0})),this.linesSinceLastSyncMark=0,this.haveWeEmittedData=!1,this.fastaMode=!1,this.minLinesBetweenSyncMarks=e.minSyncLines||100,this.insertVersionDirective=e.insertVersionDirective||!1}_transform(e,n,r){let o;if(!this.haveWeEmittedData&&this.insertVersionDirective){const i=Array.isArray(e)?e[0]:e;"directive"in i&&i.directive!=="gff-version"&&this.push(`##gff-version 3
-`)}if("sequence"in e&&!this.fastaMode&&(this.push(`##FASTA
-`),this.fastaMode=!0),Array.isArray(e)?o=e.map(vu).join(""):o=vu(e),this.push(o),this.linesSinceLastSyncMark>=this.minLinesBetweenSyncMarks)this.push(`###
-`),this.linesSinceLastSyncMark=0;else{let i=0;for(let s=0;s<o.length;s+=1)o[s]===`
-`&&(i+=1);this.linesSinceLastSyncMark+=i}this.haveWeEmittedData=!0,_0(r)}}function NM(t={}){return new Dv(t)}function zM(t,e,n={}){const r={insertVersionDirective:!0,...n};return new Promise((o,i)=>{t.pipe(new Dv(r)).on("end",()=>o(null)).on("error",i).pipe(e)})}const UM=Object.freeze(Object.defineProperty({__proto__:null,default:{parseStream:PM,parseStringSync:LM,formatSync:OM,formatStream:NM,formatFile:zM,util:FM}},Symbol.toStringTag,{value:"Module"})),Au={InfoFields:{AA:{Number:1,Type:"String",Description:"Ancestral allele"},AC:{Number:"A",Type:"Integer",Description:"Allele count in genotypes, for each ALT allele, in the same order as listed"},AD:{Number:"R",Type:"Integer",Description:"Total read depth for each allele"},ADF:{Number:"R",Type:"Integer",Description:"Read depth for each allele on the forward strand"},ADR:{Number:"R",Type:"Integer",Description:"Read depth for each allele on the reverse strand"},AF:{Number:"A",Type:"Float",Description:"Allele frequency for each ALT allele in the same order as listed (estimated from primary data, not called genotypes)"},AN:{Number:1,Type:"Integer",Description:"Total number of alleles in called genotypes"},BQ:{Number:1,Type:"Float",Description:"RMS base quality"},CIGAR:{Number:1,Type:"Float",Description:"Cigar string describing how to align an alternate allele to the reference allele"},DB:{Number:0,Type:"Flag",Description:"dbSNP membership"},DP:{Number:1,Type:"Integer",Description:"combined depth across samples"},END:{Number:1,Type:"Integer",Description:"End position (for use with symbolic alleles)"},H2:{Number:0,Type:"Flag",Description:"HapMap2 membership"},H3:{Number:0,Type:"Flag",Description:"HapMap3 membership"},MQ:{Number:1,Type:null,Description:"RMS mapping quality"},MQ0:{Number:1,Type:"Integer",Description:"Number of MAPQ == 0 reads"},NS:{Number:1,Type:"Integer",Description:"Number of samples with data"},SB:{Number:4,Type:"Integer",Description:"Strand bias"},SOMATIC:{Number:0,Type:"Flag",Description:"Somatic mutation (for cancer genomics)"},VALIDATED:{Number:0,Type:"Flag",Description:"Validated by follow-up experiment"},"1000G":{Number:0,Type:"Flag",Description:"1000 Genomes membership"},IMPRECISE:{Number:0,Type:"Flag",Description:"Imprecise structural variation"},NOVEL:{Number:0,Type:"Flag",Description:"Indicates a novel structural variation"},SVTYPE:{Number:1,Type:"String",Description:"Type of structural variant"},SVLEN:{Number:null,Type:"Integer",Description:"Difference in length between REF and ALT alleles"},CIPOS:{Number:2,Type:"Integer",Description:"Confidence interval around POS for imprecise variants"},CIEND:{Number:2,Type:"Integer",Description:"Confidence interval around END for imprecise variants"},HOMLEN:{Type:"Integer",Description:"Length of base pair identical micro-homology at event breakpoints"},HOMSEQ:{Type:"String",Description:"Sequence of base pair identical micro-homology at event breakpoints"},BKPTID:{Type:"String",Description:"ID of the assembled alternate allele in the assembly file"},MEINFO:{Number:4,Type:"String",Description:"Mobile element info of the form NAME,START,END,POLARITY"},METRANS:{Number:4,Type:"String",Description:"Mobile element transduction info of the form CHR,START,END,POLARITY"},DGVID:{Number:1,Type:"String",Description:"ID of this element in Database of Genomic Variation"},DBVARID:{Number:1,Type:"String",Description:"ID of this element in DBVAR"},DBRIPID:{Number:1,Type:"String",Description:"ID of this element in DBRIP"},MATEID:{Number:null,Type:"String",Description:"ID of mate breakends"},PARID:{Number:1,Type:"String",Description:"ID of partner breakend"},EVENT:{Number:1,Type:"String",Description:"ID of event associated to breakend"},CILEN:{Number:2,Type:"Integer",Description:"Confidence interval around the inserted material between breakend"},DPADJ:{Type:"Integer",Description:"Read Depth of adjacency"},CN:{Number:1,Type:"Integer",Description:"Copy number of segment containing breakend"},CNADJ:{Number:null,Type:"Integer",Description:"Copy number of adjacency"},CICN:{Number:2,Type:"Integer",Description:"Confidence interval around copy number for the segment"},CICNADJ:{Number:null,Type:"Integer",Description:"Confidence interval around copy number for the adjacency"}},GenotypeFields:{AD:{Number:"R",Type:"Integer",Description:"Read depth for each allele"},ADF:{Number:"R",Type:"Integer",Description:"Read depth for each allele on the forward strand"},ADR:{Number:"R",Type:"Integer",Description:"Read depth for each allele on the reverse strand"},DP:{Number:1,Type:"Integer",Description:"Read depth"},EC:{Number:"A",Type:"Integer",Description:"Expected alternate allele counts"},FT:{Number:1,Type:"String",Description:'Filter indicating if this genotype was "called"'},GL:{Number:"G",Type:"Float",Description:"Genotype likelihoods"},GP:{Number:"G",Type:"Float",Description:"Genotype posterior probabilities"},GQ:{Number:1,Type:"Integer",Description:"Conditional genotype quality"},GT:{Number:1,Type:"String",Description:"Genotype"},HQ:{Number:2,Type:"Integer",Description:"Haplotype quality"},MQ:{Number:1,Type:"Integer",Description:"RMS mapping quality"},PL:{Number:"G",Type:"Integer",Description:"Phred-scaled genotype likelihoods rounded to the closest integer"},PQ:{Number:1,Type:"Integer",Description:"Phasing quality"},PS:{Number:1,Type:"Integer",Description:"Phase set"}},AltTypes:{DEL:{Description:"Deletion relative to the reference"},INS:{Description:"Insertion of novel sequence relative to the reference"},DUP:{Description:"Region of elevated copy number relative to the reference"},INV:{Description:"Inversion of reference sequence"},CNV:{Description:"Copy number variable region (may be both deletion and duplication)"},"DUP:TANDEM":{Description:"Tandem duplication"},"DEL:ME":{Description:"Deletion of mobile element relative to the reference"},"INS:ME":{Description:"Insertion of a mobile element relative to the reference"},NON_REF:{Description:"Represents any possible alternative allele at this location"},"*":{Description:"Represents any possible alternative allele at this location"}},FilterTypes:{PASS:{Description:"Passed all filters"}}};function GM(t){try{return decodeURIComponent(t)}catch{return t}}class HM{constructor({header:e="",strict:n=!0}){if(!e.length)throw new Error("empty header received");const r=e.split(/[\r\n]+/).filter(c=>c);if(!r.length)throw new Error("no non-empty header lines specified");this.strict=n,this.metadata=JSON.parse(JSON.stringify({INFO:Au.InfoFields,FORMAT:Au.GenotypeFields,ALT:Au.AltTypes,FILTER:Au.FilterTypes}));let o;if(r.forEach(c=>{if(c.startsWith("#"))c.startsWith("##")?this.parseMetadata(c):o=c;else throw new Error(`Bad line in header:
-${c}`)}),!o)throw new Error("No format line found in header");const i=o.trim().split("	"),s=i.slice(0,8),a=["#CHROM","POS","ID","REF","ALT","QUAL","FILTER","INFO"];if(i.length<8)throw new Error(`VCF header missing columns:
-${o}`);if(s.length!==a.length||!s.every((c,l)=>c===a[l]))throw new Error(`VCF column headers not correct:
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Error("query outside of range of linear index");let m=u[d/16384].blockPosition;for(let g=d/16384,y=0;g<f/16384;g++,y++)h[y]={score:u[g+1].blockPosition-m,start:g*16384,end:g*16384+16384},m=u[g+1].blockPosition;return h.map(g=>({...g,score:g.score*((l==null?void 0:l.lineCount)||0)/p}))}async blocksForRange(e,t,r,i={}){t<0&&(t=0);const s=await this.parse(i);if(!s)return[];const o=s.indices(e);if(!o)return[];const a=e7(t,r),c=[];for(const[h,p]of a)for(let m=h;m<=p;m++)if(o.binIndex[m]){const g=o.binIndex[m];for(const y of g)c.push(new Zh(y.minv,y.maxv,m))}const u=o.linearIndex.length;let l;const f=Math.min(t>>14,u-1),d=Math.min(r>>14,u-1);for(let h=f;h<=d;++h){const p=o.linearIndex[h];p&&(!l||p.compareTo(l)<0)&&(l=p)}return Cb(c,l)}async parse(e={}){return this.setupP||(this.setupP=this._parse(e).catch(t=>{throw this.setupP=void 0,t})),this.setupP}async hasRefSeq(e,t={}){var i;return!!((i=(await this.parse(t)).indices(e))!=null&&i.binIndex)}}function t7(n){let e=0;for(const t of 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a={ref:r.getInt32(t+4,!0),start:r.getInt32(t+8,!0),end:r.getInt32(t+12,!0)},c=r.getInt32(t+16,!0),u=c?String.fromCharCode(c):"",l=r.getInt32(t+20,!0),f=r.getInt32(t+24,!0);return{columnNumbers:a,coordinateType:s,metaValue:c,metaChar:u,skipLines:l,format:o,formatFlags:i,...Yk(e.subarray(t+28,t+28+f),this.renameRefSeq)}}async _parse(e){const t=await this.filehandle.readFile(e),r=await Kh(t),i=new DataView(r.buffer);let s;const o=i.getUint32(0,!0);if(o===i7)s=1;else if(o===s7)s=2;else throw new Error(`Not a CSI file ${o}`);this.minShift=i.getInt32(4,!0),this.depth=i.getInt32(8,!0),this.maxBinNumber=((1<<(this.depth+1)*3)-1)/7;const a=this.maxBinNumber,c=i.getInt32(12,!0),u=c>=30?this.parseAuxData(r,16):void 0,l=i.getInt32(16+c,!0);let f=16+c+4,d;const h=[];for(let g=0;g<l;g++){h.push(f);const y=i.getInt32(f,!0);f+=4;for(let x=0;x<y;x++){const A=i.getUint32(f,!0);if(f+=4,A>this.maxBinNumber)f+=44;else{f+=8;const w=i.getInt32(f,!0);f+=4;for(let S=0;S<w;S+=1){const C=Xn(r,f);f+=8,f+=8,d=Xo(d,C)}}}}const p=new Vr({maxSize:5});function m(g){let y=h[g];if(y===void 0)return;const x=i.getInt32(y,!0);y+=4;const A={};let w;for(let S=0;S<x;S++){const C=i.getUint32(y,!0);if(y+=4,C>a)w=Db(r,y+28),y+=44;else{d=Xo(d,Xn(r,y)),y+=8;const v=i.getInt32(y,!0);y+=4;const T=new Array(v);for(let P=0;P<v;P+=1){const F=Xn(r,y);y+=8;const k=Xn(r,y);y+=8,T[P]=new Zh(F,k,C)}A[C]=T}}return{binIndex:A,stats:w}}return{csiVersion:s,firstDataLine:d,indices:g=>{if(!p.has(g)){const y=m(g);return y&&p.set(g,y),y}return p.get(g)},refCount:l,csi:!0,maxBlockSize:65536,...u}}async blocksForRange(e,t,r,i={}){t<0&&(t=0);const o=(await this.parse(i)).indices(e);if(!o)return[];const a=this.reg2bins(t,r);if(a.length===0)return[];const c=[];for(const[u,l]of a)for(let f=u;f<=l;f++)if(o.binIndex[f]){const d=o.binIndex[f];for(const h of d)c.push(h)}return Cb(c,new Ib(0,0))}reg2bins(e,t){e-=1,e<1&&(e=1),t>2**50&&(t=2**34),t-=1;let r=0,i=0,s=this.minShift+this.depth*3;const o=[];for(;r<=this.depth;s-=3,i+=o7(1,r*3),r+=1){const a=i+Bb(e,s),c=i+Bb(t,s);if(c-a+o.length>this.maxBinNumber)throw new Error(`query ${e}-${t} is too large for current binning scheme (shift ${this.minShift}, depth ${this.depth}), try a smaller query or a coarser index binning scheme`);o.push([a,c])}return o}async parse(e={}){return this.setupP||(this.setupP=this._parse(e).catch(t=>{throw this.setupP=void 0,t})),this.setupP}async hasRefSeq(e,t={}){var i;return!!((i=(await this.parse(t)).indices(e))!=null&&i.binIndex)}};class a7{read(){throw new Error("never called")}stat(){throw new Error("never called")}readFile(){throw new Error("never called")}close(){throw new Error("never called")}}const wt={BAM_FPAIRED:1,BAM_FPROPER_PAIR:2,BAM_FUNMAP:4,BAM_FMUNMAP:8,BAM_FREVERSE:16,BAM_FMREVERSE:32,BAM_FREAD1:64,BAM_FREAD2:128,BAM_FSECONDARY:256,BAM_FQCFAIL:512,BAM_FDUP:1024,BAM_FSUPPLEMENTARY:2048},Zo="=ACMGRSVTWYHKDBN".split(""),c7=[77,73,68,78,83,72,80,61,88,63,63,63,63,63,63,63],u7=1,l7=3,kb=4,f7=1<<u7|1<<kb|1<<5;class _r{constructor(e){this.bytes=e.bytes,this.fileOffset=e.fileOffset,this._dataView=new DataView(this.bytes.byteArray.buffer)}get byteArray(){return this.bytes.byteArray}get flags(){return(this._dataView.getInt32(this.bytes.start+16,!0)&4294901760)>>16}get ref_id(){return this._dataView.getInt32(this.bytes.start+4,!0)}get start(){return this._dataView.getInt32(this.bytes.start+8,!0)}get end(){return this.start+this.length_on_ref}get id(){return this.fileOffset}get mq(){const e=(this.bin_mq_nl&65280)>>8;return e===255?void 0:e}get score(){return this.mq}get qual(){if(this.isSegmentUnmapped())return;const e=this.b0+this.read_name_length+this.num_cigar_bytes+this.num_seq_bytes;return this.byteArray.subarray(e,e+this.seq_length)}get strand(){return this.isReverseComplemented()?-1:1}get b0(){return this.bytes.start+36}get name(){let e="";for(let t=0;t<this.read_name_length-1;t++)e+=String.fromCharCode(this.byteArray[this.b0+t]);return e}get tags(){let e=this.b0+this.read_name_length+this.num_cigar_bytes+this.num_seq_bytes+this.seq_length;const t=this.bytes.end,r={};for(;e<t;){const i=String.fromCharCode(this.byteArray[e])+String.fromCharCode(this.byteArray[e+1]),s=String.fromCharCode(this.byteArray[e+2]);switch(e+=3,s){case"A":r[i]=String.fromCharCode(this.byteArray[e]),e+=1;break;case"i":r[i]=this._dataView.getInt32(e,!0),e+=4;break;case"I":r[i]=this._dataView.getUint32(e,!0),e+=4;break;case"c":r[i]=this._dataView.getInt8(e),e+=1;break;case"C":r[i]=this._dataView.getUint8(e),e+=1;break;case"s":r[i]=this._dataView.getInt16(e,!0),e+=2;break;case"S":r[i]=this._dataView.getUint16(e,!0),e+=2;break;case"f":r[i]=this._dataView.getFloat32(e,!0),e+=4;break;case"Z":case"H":{const o=[];for(;e<=t;){const a=this.byteArray[e++];if(a!==0)o.push(String.fromCharCode(a));else break}r[i]=o.join("");break}case"B":{const o=this.byteArray[e++],a=String.fromCharCode(o),c=this._dataView.getInt32(e,!0);e+=4;const u=this.byteArray.byteOffset+e;if(a==="i"){if(u%4===0)r[i]=new Int32Array(this.byteArray.buffer,u,c);else{const l=this.byteArray.slice(e,e+(c<<2));r[i]=new Int32Array(l.buffer,l.byteOffset,c)}e+=c<<2}else if(a==="I"){if(u%4===0)r[i]=new Uint32Array(this.byteArray.buffer,u,c);else{const l=this.byteArray.slice(e,e+(c<<2));r[i]=new Uint32Array(l.buffer,l.byteOffset,c)}e+=c<<2}else if(a==="s"){if(u%2===0)r[i]=new Int16Array(this.byteArray.buffer,u,c);else{const l=this.byteArray.slice(e,e+(c<<1));r[i]=new Int16Array(l.buffer,l.byteOffset,c)}e+=c<<1}else if(a==="S"){if(u%2===0)r[i]=new Uint16Array(this.byteArray.buffer,u,c);else{const l=this.byteArray.slice(e,e+(c<<1));r[i]=new Uint16Array(l.buffer,l.byteOffset,c)}e+=c<<1}else if(a==="c")r[i]=new Int8Array(this.byteArray.buffer,u,c),e+=c;else if(a==="C")r[i]=new Uint8Array(this.byteArray.buffer,u,c),e+=c;else if(a==="f"){if(u%4===0)r[i]=new Float32Array(this.byteArray.buffer,u,c);else{const l=this.byteArray.slice(e,e+(c<<2));r[i]=new Float32Array(l.buffer,l.byteOffset,c)}e+=c<<2}break}default:console.error("Unknown BAM tag type",s);break}}return r}isPaired(){return!!(this.flags&wt.BAM_FPAIRED)}isProperlyPaired(){return!!(this.flags&wt.BAM_FPROPER_PAIR)}isSegmentUnmapped(){return!!(this.flags&wt.BAM_FUNMAP)}isMateUnmapped(){return!!(this.flags&wt.BAM_FMUNMAP)}isReverseComplemented(){return!!(this.flags&wt.BAM_FREVERSE)}isMateReverseComplemented(){return!!(this.flags&wt.BAM_FMREVERSE)}isRead1(){return!!(this.flags&wt.BAM_FREAD1)}isRead2(){return!!(this.flags&wt.BAM_FREAD2)}isSecondary(){return!!(this.flags&wt.BAM_FSECONDARY)}isFailedQc(){return!!(this.flags&wt.BAM_FQCFAIL)}isDuplicate(){return!!(this.flags&wt.BAM_FDUP)}isSupplementary(){return!!(this.flags&wt.BAM_FSUPPLEMENTARY)}get cigarAndLength(){if(this.isSegmentUnmapped())return{length_on_ref:0,NUMERIC_CIGAR:new Uint32Array(0)};const e=this.num_cigar_ops;let t=this.b0+this.read_name_length;const r=this._dataView.getInt32(t,!0),i=r>>4;if((r&15)===kb&&i===this.seq_length){t+=4;const o=this._dataView.getInt32(t,!0),a=o>>4;return(o&15)!==l7&&console.warn("CG tag with no N tag"),{NUMERIC_CIGAR:this.tags.CG,length_on_ref:a}}else{const o=this.byteArray.byteOffset+t,a=o%4===0?new Uint32Array(this.byteArray.buffer,o,e):new Uint32Array(this.byteArray.slice(t,t+(e<<2)).buffer,0,e);let c=0;for(let u=0;u<e;++u){const l=a[u];1<<(l&15)&f7||(c+=l>>4)}return{NUMERIC_CIGAR:a,length_on_ref:c}}}get length_on_ref(){return this.cigarAndLength.length_on_ref}get NUMERIC_CIGAR(){return this.cigarAndLength.NUMERIC_CIGAR}get CIGAR(){const e=this.NUMERIC_CIGAR;let t="";for(let r=0,i=e.length;r<i;r++){const s=e[r],o=s>>4,a=c7[s&15];t+=o+String.fromCharCode(a)}return t}get num_cigar_ops(){return this.flag_nc&65535}get num_cigar_bytes(){return this.num_cigar_ops<<2}get read_name_length(){return this.bin_mq_nl&255}get num_seq_bytes(){return this.seq_length+1>>1}get NUMERIC_SEQ(){const e=this.b0+this.read_name_length+this.num_cigar_bytes,t=this.byteArray.subarray(e,e+this.num_seq_bytes);return new Uint8Array(t.buffer,t.byteOffset,this.num_seq_bytes)}get seq(){const e=this.NUMERIC_SEQ,t=this.seq_length,r=new Array(t);let i=0;const s=t>>1;for(let o=0;o<s;++o){const a=e[o];r[i++]=Zo[(a&240)>>4],r[i++]=Zo[a&15]}if(i<t){const o=e[s];r[i]=Zo[(o&240)>>4]}return r.join("")}get pair_orientation(){if(!this.isSegmentUnmapped()&&!this.isMateUnmapped()&&this.ref_id===this.next_refid){const e=this.isReverseComplemented()?"R":"F",t=this.isMateReverseComplemented()?"R":"F";let r=" ",i=" ";this.isRead1()?(r="1",i="2"):this.isRead2()&&(r="2",i="1");const s=[];return this.template_length>0?(s[0]=e,s[1]=r,s[2]=t,s[3]=i):(s[2]=e,s[3]=r,s[0]=t,s[1]=i),s.join("")}}get bin_mq_nl(){return this._dataView.getInt32(this.bytes.start+12,!0)}get flag_nc(){return this._dataView.getInt32(this.bytes.start+16,!0)}get seq_length(){return this._dataView.getInt32(this.bytes.start+20,!0)}get next_refid(){return this._dataView.getInt32(this.bytes.start+24,!0)}get next_pos(){return this._dataView.getInt32(this.bytes.start+28,!0)}get template_length(){return this._dataView.getInt32(this.bytes.start+32,!0)}seqAt(e){if(e<this.seq_length){const t=e>>1,r=this.byteArray[this.b0+this.read_name_length+this.num_cigar_bytes+t];return e%2===0?Zo[(r&240)>>4]:Zo[r&15]}else return}toJSON(){const e={};for(const t of Object.keys(this))t.startsWith("_")||t==="bytes"||(e[t]=this[t]);return e}}function Ko(n,e){const t=Object.getOwnPropertyDescriptor(n.prototype,e);if(!t)throw new Error("OH NO, NO PROPERTY DESCRIPTOR");const r=t.get;if(!r)throw new Error("OH NO, NOT A GETTER");Object.defineProperty(n.prototype,e,{get(){const i=r.call(this);return Object.defineProperty(this,e,{value:i}),i}})}Ko(_r,"tags"),Ko(_r,"cigarAndLength"),Ko(_r,"seq"),Ko(_r,"qual"),Ko(_r,"end");function Fb(n){const e=n.split(/\r?\n/),t=[];for(const r of e){const[i,...s]=r.split(/\t/);i&&t.push({tag:i.slice(1),data:s.map(o=>{const a=o.indexOf(":"),c=o.slice(0,a),u=o.slice(a+1);return{tag:c,value:u}})})}return t}const Pb=21840194,h7=65536;class Mb{constructor({bamFilehandle:e,bamPath:t,bamUrl:r,baiPath:i,baiFilehandle:s,baiUrl:o,csiPath:a,csiFilehandle:c,csiUrl:u,htsget:l,renameRefSeqs:f=d=>d}){if(this.htsget=!1,this.cache=new Vr({maxSize:1e3}),this.renameRefSeq=f,e)this.bam=e;else if(t)this.bam=new qe(t);else if(r)this.bam=new Yt(r);else if(l)this.htsget=!0,this.bam=new a7;else throw new Error("unable to initialize bam");if(c)this.index=new xu({filehandle:c});else if(a)this.index=new xu({filehandle:new qe(a)});else if(u)this.index=new xu({filehandle:new Yt(u)});else if(s)this.index=new qi({filehandle:s});else if(i)this.index=new qi({filehandle:new qe(i)});else if(o)this.index=new qi({filehandle:new Yt(o)});else if(t)this.index=new qi({filehandle:new qe(`${t}.bai`)});else if(r)this.index=new qi({filehandle:new Yt(`${r}.bai`)});else if(l)this.htsget=!0;else throw new Error("unable to infer index format")}async getHeaderPre(e){const t=qk(e);if(!this.index)return;const r=await this.index.parse(t),i=r.firstDataLine===void 0?await this.bam.readFile():await this.bam.read(r.firstDataLine.blockPosition+h7,0),s=await Kh(i),o=new DataView(s.buffer);if(o.getInt32(0,!0)!==Pb)throw new Error("Not a BAM file");const a=o.getInt32(4,!0),c=new TextDecoder("utf8");this.header=c.decode(s.subarray(8,8+a));const{chrToIndex:u,indexToChr:l}=this._parseRefSeqs(s,a+8);return this.chrToIndex=u,this.indexToChr=l,Fb(this.header)}getHeader(e){return this.headerP||(this.headerP=this.getHeaderPre(e).catch(t=>{throw this.headerP=void 0,t})),this.headerP}async getHeaderText(e={}){return await this.getHeader(e),this.header}_parseRefSeqs(e,t){const r=new DataView(e.buffer),i=r.getInt32(t,!0);let s=t+4;const o={},a=[],c=new TextDecoder("utf8");for(let u=0;u<i;u+=1){if(s+8>e.length)throw new Error(`Insufficient data for reference sequences: need more than ${e.length} bytes`);const l=r.getInt32(s,!0),f=this.renameRefSeq(c.decode(e.subarray(s+4,s+4+l-1))),d=r.getInt32(s+l+4,!0);o[f]=u,a.push({refName:f,length:d}),s=s+8+l}return{chrToIndex:o,indexToChr:a}}async getRecordsForRange(e,t,r,i){return Zk(this.streamRecordsForRange(e,t,r,i))}async*streamRecordsForRange(e,t,r,i){var a;await this.getHeader(i);const s=(a=this.chrToIndex)==null?void 0:a[e];if(s===void 0||!this.index)return;const o=await this.index.blocksForRange(s,t-1,r,i);yield*this._fetchChunkFeatures(o,s,t,r,i)}async*_fetchChunkFeatures(e,t,r,i,s={}){const{viewAsPairs:o}=s,a=[];let c=!1;for(const u of e){const{data:l,cpositions:f,dpositions:d}=await this._readChunk({chunk:u,opts:s}),h=await this.readBamFeatures(l,f,d,u,t,r,i),p=[];for(const m of h)if(m.ref_id===t)if(m.start>=i){c=!0;break}else m.end>=r&&p.push(m);if(a.push(p),yield p,c)break}o&&(yield this.fetchPairs(t,a,s))}async fetchPairs(e,t,r){const{pairAcrossChr:i,maxInsertSize:s=2e5}=r,o={},a={};for(const d of t){const h={};for(const p of d){const m=p.name,g=p.id;h[m]||(h[m]=0),h[m]++,a[g]=1}for(const[p,m]of Object.entries(h))m===1&&(o[p]=!0)}const c=[];for(const d of t)for(const h of d){const p=h.name,m=h.start,g=h.next_pos,y=h.next_refid;this.index&&o[p]&&(i||y===e&&Math.abs(m-g)<s)&&c.push(this.index.blocksForRange(y,g,g+1,r))}const u=new Map,l=await Promise.all(c);for(const d of l.flat())u.has(d.toString())||u.set(d.toString(),d);return(await Promise.all([...u.values()].map(async d=>{const{data:h,cpositions:p,dpositions:m,chunk:g}=await this._readChunk({chunk:d,opts:r}),y=[];for(const x of await this.readBamFeatures(h,p,m,g))o[x.name]&&!a[x.id]&&y.push(x);return y}))).flat()}async _readChunk({chunk:e,opts:t}){const r=await this.bam.read(e.fetchedSize(),e.minv.blockPosition,t),{buffer:i,cpositions:s,dpositions:o}=await n7(r,e,this.cache);return{data:i,cpositions:s,dpositions:o,chunk:e}}async readBamFeatures(e,t,r,i,s,o,a){let c=0;const u=[];let l=0;const f=new DataView(e.buffer),d=r.length>0,h=t.length>0,p=s!==void 0&&o!==void 0&&a!==void 0;for(;c+4<e.length;){const m=f.getInt32(c,!0),g=c+4+m-1;if(d){for(;c+i.minv.dataPosition>=r[l++];);l--}if(g<e.length){if(p&&c+12<e.length&&!this._shouldIncludeFeature(f,c,s,a)){c=g+1;continue}const y=new _r({bytes:{byteArray:e,start:c,end:g},fileOffset:h?t[l]*256+(c-r[l])+i.minv.dataPosition+1:r7(e.subarray(c,g))>>>0});u.push(y)}c=g+1}return u}_shouldIncludeFeature(e,t,r,i){const s=e.getInt32(t+4,!0),o=e.getInt32(t+8,!0);return s===r&&o<i}async hasRefSeq(e){var r,i;const t=(r=this.chrToIndex)==null?void 0:r[e];return t===void 0?!1:(i=this.index)==null?void 0:i.hasRefSeq(t)}async lineCount(e){var r;const t=(r=this.chrToIndex)==null?void 0:r[e];return t===void 0||!this.index?0:this.index.lineCount(t)}async indexCov(e,t,r){var s;if(!this.index)return[];await this.index.parse();const i=(s=this.chrToIndex)==null?void 0:s[e];return i===void 0?[]:this.index.indexCov(i,t,r)}async blocksForRange(e,t,r,i){var o;if(!this.index)return[];await this.index.parse();const s=(o=this.chrToIndex)==null?void 0:o[e];return s===void 0?[]:this.index.blocksForRange(s,t,r,i)}}async function Rb(n,e){const t=await Promise.all(n.map(async r=>{const{url:i,headers:s}=r;if(i.startsWith("data:")){const o=await fetch(i);if(!o.ok)throw new Error("failed to decode base64");const a=await o.arrayBuffer();return new Uint8Array(a)}else{const{referer:o,...a}=s,c=await fetch(i,{...e,headers:{...e==null?void 0:e.headers,...a}});if(!c.ok)throw new Error(`HTTP ${c.status} fetching ${i}: ${await c.text()}`);return new Uint8Array(await c.arrayBuffer())}}));return Xk(await Promise.all(t.map(r=>Kh(r))))}class d7 extends Mb{constructor(e){super({htsget:!0}),this.baseUrl=e.baseUrl,this.trackId=e.trackId}async*streamRecordsForRange(e,t,r,i){var c;const o=`${`${this.baseUrl}/${this.trackId}`}?referenceName=${e}&start=${t}&end=${r}&format=BAM`,a=(c=this.chrToIndex)==null?void 0:c[e];if(a===void 0)yield[];else{const u=await fetch(o,{...i});if(!u.ok)throw new Error(`HTTP ${u.status} fetching ${o}: ${await u.text()}`);const l=await u.json(),f=await Rb(l.htsget.urls.slice(1),i);yield*this._fetchChunkFeatures([{buffer:f,_fetchedSize:void 0,bin:0,compareTo(){return 0},toUniqueString(){return`${e}_${t}_${r}`},fetchedSize(){return 0},minv:{dataPosition:0,blockPosition:0,compareTo:()=>0},maxv:{dataPosition:Number.MAX_SAFE_INTEGER,blockPosition:0,compareTo:()=>0},toString(){return`${e}_${t}_${r}`}}],a,t,r,i)}}async _readChunk({chunk:e}){if(!e.buffer)throw new Error("expected chunk.buffer in htsget");return{data:e.buffer,cpositions:[],dpositions:[],chunk:e}}async getHeader(e={}){const t=`${this.baseUrl}/${this.trackId}?referenceName=na&class=header`,r=await fetch(t,e);if(!r.ok)throw new Error(`HTTP ${r.status} fetching ${t}: ${await r.text()}`);const i=await r.json(),s=await Rb(i.htsget.urls,e),o=new DataView(s.buffer);if(o.getInt32(0,!0)!==Pb)throw new Error("Not a BAM file");const a=o.getInt32(4,!0),u=new TextDecoder("utf8").decode(s.subarray(8,8+a)),l=Fb(u),f=[],d={},h=l.filter(p=>p.tag==="SQ");for(const[p,m]of h.entries()){let g="",y=0;for(const x of m.data)x.tag==="SN"?g=x.value:x.tag==="LN"&&(y=+x.value);d[g]=p,f[p]={refName:g,length:y}}return this.chrToIndex=d,this.indexToChr=f,l}}const p7=Object.freeze(Object.defineProperty({__proto__:null,BAI:qi,BamFile:Mb,BamRecord:_r,CSI:xu,HtsgetFile:d7},Symbol.toStringTag,{value:"Module"}));function m7(n){let e=0;for(const t of n)e+=t.length;return e}function Ob(n,e){const t=new Uint8Array(e??m7(n));let r=0;for(const i of n)t.set(i,r),r+=i.length;return t}async function $h(n){try{let e,t=0,r;const i=[];let s=0;do{const o=n.subarray(t);if(r=new dn(void 0),{strm:e}=r,r.push(o,zr),r.err)throw new Error(r.msg);t+=e.next_in;const a=r.result;i.push(a),s+=a.length}while(e.avail_in);return Ob(i,s)}catch(e){throw/incorrect header check/.exec(`${e}`)?new Error("problem decompressing block: incorrect gzip header check"):e}}async function g7(n,e,t){try{let r;const{minv:i,maxv:s}=e;let o=i.blockPosition,a=i.dataPosition;const c=[],u=[],l=[];let f=0,d=!1,h=0;do{const p=n.subarray(o-i.blockPosition),m=o.toString();let g,y;const x=t==null?void 0:t.get(m);if(x)g=x.buffer,y=x.nextIn,d=!0;else{const S=new dn(void 0);if({strm:r}=S,S.push(p,zr),S.err)throw new Error(S.msg);g=S.result,y=r.next_in,d=!1,t==null||t.set(m,{buffer:g,nextIn:y})}c.push(g);let A=g.length;u.push(o),l.push(a),c.length===1&&i.dataPosition&&(c[0]=c[0].subarray(i.dataPosition),A=c[0].length);const w=o;if(o+=y,a+=A,w>=s.blockPosition){c[f]=c[f].subarray(0,s.blockPosition===i.blockPosition?s.dataPosition-i.dataPosition+1:s.dataPosition+1),h+=c[f].length,u.push(o),l.push(a);break}h+=A,f++}while(d?o<n.length+i.blockPosition:r.avail_in);return{buffer:Ob(c,h),cpositions:u,dpositions:l}}catch(r){throw/incorrect header check/.exec(`${r}`)?new Error("problem decompressing block: incorrect gzip header check"):r}}class Au{constructor(e,t,r,i){this.minv=e,this.maxv=t,this.bin=r,this._fetchedSize=i}toUniqueString(){return`${this.minv}..${this.maxv} (bin ${this.bin}, fetchedSize ${this.fetchedSize()})`}toString(){return this.toUniqueString()}compareTo(e){return this.minv.compareTo(e.minv)||this.maxv.compareTo(e.maxv)||this.bin-e.bin}fetchedSize(){return this._fetchedSize!==void 0?this._fetchedSize:this.maxv.blockPosition+65536-this.minv.blockPosition}}class Nb{constructor({filehandle:e,renameRefSeqs:t=r=>r}){this.filehandle=e,this.renameRefSeq=t}async getMetadata(e={}){const{indices:t,...r}=await this.parse(e);return r}_findFirstData(e,t){return e?e.compareTo(t)>0?t:e:t}async parse(e={}){return this.parseP||(this.parseP=this._parse(e).catch(t=>{throw this.parseP=void 0,t})),this.parseP}async hasRefSeq(e,t={}){var i;return!!((i=(await this.parse(t)).indices[e])!=null&&i.binIndex)}_parseNameBytes(e){let t=0,r=0;const i=[],s={},o=new TextDecoder("utf8");for(let a=0;a<e.length;a+=1)if(!e[a]){if(r<a){const c=this.renameRefSeq(o.decode(e.subarray(r,a)));i[t]=c,s[c]=t}r=a+1,t+=1}return{refNameToId:s,refIdToName:i}}}const Lb=65536,y7=Lb*Lb;function zb(n,e=0){const t=n[e]|n[e+1]<<8|n[e+2]<<16|n[e+3]<<24;return((n[e+4]|n[e+5]<<8|n[e+6]<<16|n[e+7]<<24)>>>0)*y7+(t>>>0)}class b7 extends Error{}function Jo(n){if(n&&n.aborted)if(typeof DOMException>"u"){const e=new b7("aborted");throw e.code="ERR_ABORTED",e}else throw new DOMException("aborted","AbortError")}function x7(n,e){return e.minv.blockPosition-n.maxv.blockPosition<65e3&&e.maxv.blockPosition-n.minv.blockPosition<5e6}function Ub(n,e){const t=[];let r;if(n.length===0)return n;n.sort(function(i,s){const o=i.minv.blockPosition-s.minv.blockPosition;return o===0?i.minv.dataPosition-s.minv.dataPosition:o});for(const i of n)(!e||i.maxv.compareTo(e)>0)&&(r===void 0?(t.push(i),r=i):x7(r,i)?i.maxv.compareTo(r.maxv)>0&&(r.maxv=i.maxv):(t.push(i),r=i));return t}class ed{constructor(e,t){this.blockPosition=e,this.dataPosition=t}toString(){return`${this.blockPosition}:${this.dataPosition}`}compareTo(e){return this.blockPosition-e.blockPosition||this.dataPosition-e.dataPosition}}function Yi(n,e=0){return new ed(n[e+7]*1099511627776+n[e+6]*4294967296+n[e+5]*16777216+n[e+4]*65536+n[e+3]*256+n[e+2],n[e+1]<<8|n[e])}const A7=21582659,w7=38359875,v7={0:"generic",1:"SAM",2:"VCF"};function S7(n,e){return n*2**e}function Gb(n,e){return Math.floor(n/2**e)}class wu extends Nb{constructor(e){super(e),this.maxBinNumber=0,this.depth=0,this.minShift=0}async lineCount(e,t={}){const r=await this.parse(t),i=r.refNameToId[e];if(i===void 0||!r.indices[i])return-1;const{stats:o}=r.indices[i];return o?o.lineCount:-1}indexCov(){throw new Error("CSI indexes do not support indexcov")}parseAuxData(e,t){const r=new DataView(e.buffer),i=r.getInt32(t,!0),s=i&65536?"zero-based-half-open":"1-based-closed",o=v7[i&15];if(!o)throw new Error(`invalid Tabix preset format flags ${i}`);const a={ref:r.getInt32(t+4,!0),start:r.getInt32(t+8,!0),end:r.getInt32(t+12,!0)},c=r.getInt32(t+16,!0),u=c?String.fromCharCode(c):void 0,l=r.getInt32(t+20,!0),f=r.getInt32(t+24,!0),{refIdToName:d,refNameToId:h}=this._parseNameBytes(e.subarray(t+28,t+28+f));return{refIdToName:d,refNameToId:h,skipLines:l,metaChar:u,columnNumbers:a,format:o,coordinateType:s}}async _parse(e={}){const t=await $h(await this.filehandle.readFile(e)),r=new DataView(t.buffer);let i;if(r.getUint32(0,!0)===A7)i=1;else if(r.getUint32(0,!0)===w7)i=2;else throw new Error("Not a CSI file");this.minShift=r.getInt32(4,!0),this.depth=r.getInt32(8,!0),this.maxBinNumber=((1<<(this.depth+1)*3)-1)/7;const s=2**(this.minShift+this.depth*3),o=r.getInt32(12,!0),a=o&&o>=30?this.parseAuxData(t,16):{refIdToName:[],refNameToId:{},metaChar:void 0,columnNumbers:{ref:0,start:1,end:2},coordinateType:"zero-based-half-open",format:"generic"},c=r.getInt32(16+o,!0);let u,l=16+o+4;const f=new Array(c).fill(0).map(()=>{const d=r.getInt32(l,!0);l+=4;const h={};let p;for(let m=0;m<d;m+=1){const g=r.getUint32(l,!0);if(g>this.maxBinNumber)p=this.parsePseudoBin(t,l+4),l+=48;else{const y=Yi(t,l+4);u=this._findFirstData(u,y);const x=r.getInt32(l+12,!0);l+=16;const A=new Array(x);for(let w=0;w<x;w+=1){const S=Yi(t,l),C=Yi(t,l+8);l+=16,A[w]=new Au(S,C,g)}h[g]=A}}return{binIndex:h,stats:p}});return{...a,csi:!0,refCount:c,maxBlockSize:65536,firstDataLine:u,csiVersion:i,indices:f,depth:this.depth,maxBinNumber:this.maxBinNumber,maxRefLength:s}}parsePseudoBin(e,t){return{lineCount:zb(e,t+28)}}async blocksForRange(e,t,r,i={}){t<0&&(t=0);const s=await this.parse(i),o=s.refNameToId[e];if(o===void 0)return[];const a=s.indices[o];if(!a)return[];const c=this.reg2bins(t,r),u=[];for(const[l,f]of c)for(let d=l;d<=f;d++)if(a.binIndex[d])for(const h of a.binIndex[d])u.push(new Au(h.minv,h.maxv,d));return Ub(u,new ed(0,0))}reg2bins(e,t){e-=1,e<1&&(e=1),t>2**50&&(t=2**34),t-=1;let r=0,i=0,s=this.minShift+this.depth*3;const o=[];for(;r<=this.depth;s-=3,i+=S7(1,r*3),r+=1){const a=i+Gb(e,s),c=i+Gb(t,s);if(c-a+o.length>this.maxBinNumber)throw new Error(`query ${e}-${t} is too large for current binning scheme (shift ${this.minShift}, depth ${this.depth}), try a smaller query or a coarser index binning scheme`);o.push([a,c])}return o}}const E7=21578324,Hb=14;function C7(n,e){return n+=1,e-=1,[[0,0],[1+(n>>26),1+(e>>26)],[9+(n>>23),9+(e>>23)],[73+(n>>20),73+(e>>20)],[585+(n>>17),585+(e>>17)],[4681+(n>>14),4681+(e>>14)]]}class Xi extends Nb{async lineCount(e,t={}){var o;const r=await this.parse(t),i=r.refNameToId[e];return i===void 0||!r.indices[i]?-1:((o=r.indices[i].stats)==null?void 0:o.lineCount)??-1}async _parse(e={}){const t=await this.filehandle.readFile(e),r=await $h(t);Jo(e.signal);const i=new DataView(r.buffer);if(i.getUint32(0,!0)!==E7)throw new Error("Not a TBI file");const o=i.getUint32(4,!0),a=i.getUint32(8,!0),c=a&65536?"zero-based-half-open":"1-based-closed",l={0:"generic",1:"SAM",2:"VCF"}[a&15];if(!l)throw new Error(`invalid Tabix preset format flags ${a}`);const f={ref:i.getInt32(12,!0),start:i.getInt32(16,!0),end:i.getInt32(20,!0)},d=i.getInt32(24,!0),h=5,p=((1<<(h+1)*3)-1)/7,m=2**(14+h*3),g=d?String.fromCharCode(d):void 0,y=i.getInt32(28,!0),x=i.getInt32(32,!0),{refNameToId:A,refIdToName:w}=this._parseNameBytes(r.slice(36,36+x));let S=36+x,C;return{indices:new Array(o).fill(0).map(()=>{const T=i.getInt32(S,!0);S+=4;const P={};let F;for(let U=0;U<T;U+=1){const j=i.getUint32(S,!0);if(S+=4,j>p+1)throw new Error("tabix index contains too many bins, please use a CSI index");if(j===p+1){const K=i.getInt32(S,!0);S+=4,K===2&&(F=this.parsePseudoBin(r,S)),S+=16*K}else{const K=i.getInt32(S,!0);S+=4;const _=new Array(K);for(let te=0;te<K;te+=1){const ce=Yi(r,S),ie=Yi(r,S+8);S+=16,C=this._findFirstData(C,ce),_[te]=new Au(ce,ie,j)}P[j]=_}}const k=i.getInt32(S,!0);S+=4;const L=new Array(k);for(let U=0;U<k;U+=1)L[U]=Yi(r,S),S+=8,C=this._findFirstData(C,L[U]);return{binIndex:P,linearIndex:L,stats:F}}),metaChar:g,maxBinNumber:p,maxRefLength:m,skipLines:y,firstDataLine:C,columnNumbers:f,coordinateType:c,format:l,refIdToName:w,refNameToId:A,maxBlockSize:65536}}parsePseudoBin(e,t){return{lineCount:zb(e,t+16)}}async blocksForRange(e,t,r,i={}){t<0&&(t=0);const s=await this.parse(i),o=s.refNameToId[e];if(o===void 0)return[];const a=s.indices[o];if(!a)return[];(a.linearIndex.length>0?a.linearIndex[t>>Hb>=a.linearIndex.length?a.linearIndex.length-1:t>>Hb]:new ed(0,0))||console.warn("querying outside of possible tabix range");const u=C7(t,r),l=[];for(const[m,g]of u)for(let y=m;y<=g;y++)if(a.binIndex[y])for(const x of a.binIndex[y])l.push(new Au(x.minv,x.maxv,y));const f=a.linearIndex.length;let d;const h=Math.min(t>>14,f-1),p=Math.min(r>>14,f-1);for(let m=h;m<=p;++m){const g=a.linearIndex[m];g&&(!d||g.compareTo(d)<0)&&(d=g)}return Ub(l,d)}}class D7{constructor({path:e,filehandle:t,url:r,tbiPath:i,tbiUrl:s,tbiFilehandle:o,csiPath:a,csiUrl:c,csiFilehandle:u,renameRefSeqs:l=d=>d,chunkCacheSize:f=5*2**20}){if(this.cache=new Vr({maxSize:1e3}),t)this.filehandle=t;else if(e)this.filehandle=new qe(e);else if(r)this.filehandle=new Yt(r);else throw new TypeError("must provide either filehandle or path");if(o)this.index=new Xi({filehandle:o,renameRefSeqs:l});else if(u)this.index=new wu({filehandle:u,renameRefSeqs:l});else if(i)this.index=new Xi({filehandle:new qe(i),renameRefSeqs:l});else if(a)this.index=new wu({filehandle:new qe(a),renameRefSeqs:l});else if(e)this.index=new Xi({filehandle:new qe(`${e}.tbi`),renameRefSeqs:l});else if(c)this.index=new wu({filehandle:new Yt(c)});else if(s)this.index=new Xi({filehandle:new Yt(s)});else if(r)this.index=new Xi({filehandle:new Yt(`${r}.tbi`)});else throw new TypeError("must provide one of tbiFilehandle, tbiPath, csiFilehandle, csiPath, tbiUrl, csiUrl");this.renameRefSeq=l,this.chunkCache=new _i({cache:new Vr({maxSize:Math.floor(f/65536)}),fill:(d,h)=>this.readChunk(d,{signal:h})})}calculateFileOffset(e,t,r,i,s){return e[r]*256+(i-t[r])+s+1}async getLines(e,t,r,i){let s,o={},a;typeof i=="function"?a=i:(o=i,a=i.lineCallback,s=i.signal);const c=await this.index.getMetadata(o);Jo(s);const u=t??0,l=r??c.maxRefLength;if(!(u<=l))throw new TypeError("invalid start and end coordinates. start must be less than or equal to end");if(u===l)return;const f=await this.index.blocksForRange(e,u,l,o);Jo(s);const d=new TextDecoder("utf8");for(const h of f){const{buffer:p,cpositions:m,dpositions:g}=await this.chunkCache.get(h.toString(),h,s);Jo(s);let y=0,x=0;const A=d.decode(p);if(p.length==A.length)for(;y<A.length;){const S=A.indexOf(`
+`,y);if(S===-1)break;const C=A.slice(y,S);if(g){const P=y+h.minv.dataPosition;for(;x<g.length&&P>=g[x];)x++}const{startCoordinate:v,overlaps:T}=this.checkLine(c,e,u,l,C);if(T)a(C,this.calculateFileOffset(m,g,x,y,h.minv.dataPosition));else if(v!==void 0&&v>=l)return;y=S+1}else for(;y<p.length;){const S=p.indexOf(10,y);if(S===-1)break;const C=p.slice(y,S),v=d.decode(C);if(g){const F=y+h.minv.dataPosition;for(;x<g.length&&F>=g[x];)x++}const{startCoordinate:T,overlaps:P}=this.checkLine(c,e,u,l,v);if(P)a(v,this.calculateFileOffset(m,g,x,y,h.minv.dataPosition));else if(T!==void 0&&T>=l)return;y=S+1}}}async getMetadata(e={}){return this.index.getMetadata(e)}async getHeaderBuffer(e={}){const{firstDataLine:t,metaChar:r,maxBlockSize:i}=await this.getMetadata(e);Jo(e.signal);const s=((t==null?void 0:t.blockPosition)||0)+i,o=await this.filehandle.read(s,0,e),a=await $h(o);if(r){let c=-1;const u=10,l=r.charCodeAt(0);for(let f=0,d=a.length;f<d;f++){const h=a[f];if(f===c+1&&h!==l)break;h===u&&(c=f)}return a.subarray(0,c+1)}return a}async getHeader(e={}){const t=new TextDecoder("utf8"),r=await this.getHeaderBuffer(e);return t.decode(r)}async getReferenceSequenceNames(e={}){return(await this.getMetadata(e)).refIdToName}checkLine(e,t,r,i,s){const{columnNumbers:o,metaChar:a,coordinateType:c,format:u}=e;if(a&&s.startsWith(a))return{overlaps:!1};let{ref:l,start:f,end:d}=o;l||(l=0),f||(f=0),d||(d=0),u==="VCF"&&(d=8);const h=Math.max(l,f,d);let p=1,m=0,g="",y=-1/0;const x=s.length;for(let A=0;A<x+1;A++)if(s[A]==="	"||A===x){if(p===l){if(this.renameRefSeq(s.slice(m,A))!==t)return{overlaps:!1}}else if(p===f){if(y=Number.parseInt(s.slice(m,A),10),c==="1-based-closed"&&(y-=1),y>=i)return{startCoordinate:y,overlaps:!1};if((d===0||d===f)&&y+1<=r)return{startCoordinate:y,overlaps:!1}}else if(u==="VCF"&&p===4)g=s.slice(m,A);else if(p===d&&(u==="VCF"?this._getVcfEnd(y,g,s.slice(m,A)):Number.parseInt(s.slice(m,A),10))<=r)return{overlaps:!1};if(p===h)break;m=A+1,p+=1}return{startCoordinate:y,overlaps:!0}}_getVcfEnd(e,t,r){let i=e+t.length;const s=r.includes("SVTYPE=TRA");if(r[0]!=="."&&!s){const a=/(?:^|;)END=([^;]+)/.exec(r);a&&(i=Number.parseInt(a[1],10))}else if(s)return e+1;return i}async lineCount(e,t={}){return this.index.lineCount(e,t)}async readChunk(e,t={}){const r=await this.filehandle.read(e.fetchedSize(),e.minv.blockPosition,t);return g7(r,e,this.cache)}}const I7=Object.freeze(Object.defineProperty({__proto__:null,CSI:wu,TBI:Xi,TabixIndexedFile:D7},Symbol.toStringTag,{value:"Module"})),T7=/%([0-9A-Fa-f]{2})/g,B7=/^\s*##\s*(\S+)\s*(.*)/,k7=/\r?\n$/,Vb=/\s+/,_b=/\D/g;function vu(n){return n.includes("%")?n.replaceAll(T7,(e,t)=>String.fromCharCode(parseInt(t,16))):n}function F7(n){if(!n.length||n===".")return{};const e={};let t=n;t.endsWith(`
+`)&&(t=t.slice(0,t.endsWith(`\r
+`)?-2:-1));for(const r of t.split(";")){const i=r.indexOf("=");if(i===-1)continue;const s=r.slice(i+1);if(!s.length)continue;const o=r.slice(0,i).trim();let a=e[o];a||(a=[],e[o]=a);for(const c of s.split(","))a.push(vu(c.trim()))}return e}function P7(n){return jb(n.split("	"))}function pn(n){return n==="."||n===""||n===void 0?null:n}function jb(n){const e=pn(n[0]),t=pn(n[1]),r=pn(n[2]),i=pn(n[3]),s=pn(n[4]),o=pn(n[5]),a=pn(n[6]),c=pn(n[7]),u=pn(n[8]);return{seq_id:e?vu(e):null,source:t?vu(t):null,type:r?vu(r):null,start:i===null?null:parseInt(i,10),end:s===null?null:parseInt(s,10),score:o===null?null:parseFloat(o),strand:a,phase:c,attributes:u===null?null:F7(u)}}function M7(n){var s,o;const e=B7.exec(n);if(!e)return null;const[,t]=e;let[,,r]=e;const i={directive:t};if(r.length&&(r=r.replace(k7,""),i.value=r),t==="sequence-region"){const a=r.split(Vb,3);return{...i,seq_id:a[0],start:(s=a[1])==null?void 0:s.replaceAll(_b,""),end:(o=a[2])==null?void 0:o.replaceAll(_b,"")}}else if(t==="genome-build"){const[a,c]=r.split(Vb,2);return{...i,source:a,buildName:c}}return i}const R7=/^\s*[^#\s>]/,O7=/^\s*(#+)(.*)/,N7=/^\s*$/,L7=/^\s*>/,z7=/\r?\n?$/g;class td{constructor(e){Y(this,"featureCallback");Y(this,"endCallback");Y(this,"commentCallback");Y(this,"errorCallback");Y(this,"disableDerivesFromReferences");Y(this,"directiveCallback");Y(this,"bufferSize");Y(this,"eof",!1);Y(this,"lineNumber",0);Y(this,"_underConstructionTopLevel",[]);Y(this,"_underConstructionById",{});Y(this,"_completedReferences",{});Y(this,"_underConstructionOrphans",{});const t=()=>{};this.featureCallback=e.featureCallback||t,this.endCallback=e.endCallback||t,this.commentCallback=e.commentCallback||t,this.errorCallback=e.errorCallback||t,this.directiveCallback=e.directiveCallback||t,this.disableDerivesFromReferences=e.disableDerivesFromReferences||!1,this.bufferSize=e.bufferSize===void 0?1/0:e.bufferSize}addLine(e){if(this.eof)return;if(this.lineNumber+=1,R7.test(e)){this._bufferLine(e);return}const t=O7.exec(e);if(t){const[,r]=t;let[,,i]=t;if(r.length===3)this._emitAllUnderConstructionFeatures();else if(r.length===2){const s=M7(e);s&&(s.directive==="FASTA"?(this._emitAllUnderConstructionFeatures(),this.eof=!0):this._emitItem(s))}else this._emitItem({comment:i.trimStart()})}else if(!N7.test(e))if(L7.test(e))this._emitAllUnderConstructionFeatures(),this.eof=!0;else{const r=e.replaceAll(z7,"");throw new Error(`GFF3 parse error.  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