@genome-spy/core 0.28.2 → 0.29.0

package/dist/index.js

@@ -82,12 +82,12 @@ return true;}return false;}`,ew="in highp vec4 vPickingColor;",bo=Symbol("cacheM
 
 ^^^ ${u}`:""}`}).join(`
 `)}function sw(t,e,n){const r=t.createProgram();t.attachShader(r,e),t.attachShader(r,n),t.linkProgram(r);function i(){let o,s;if(!t.getProgramParameter(r,t.LINK_STATUS)){o=t.getProgramInfoLog(r);for(const u of[e,n])t.getShaderParameter(u,t.COMPILE_STATUS)||(o=t.getShaderInfoLog(u),s=ow(t.getShaderSource(u),o,0)+`
-Error compiling: ${o}`,t.deleteShader(u));t.deleteProgram(r)}if(o)return{message:o,detail:s}}return{program:r,getProgramErrors:i}}function vo(t,e,n,r){return r?_f(t,r,n,e):r=Qr(t,{...e,src:n}),r}function aw(...t){const e={get(n,r,i){for(const o of t){const a=o()[r];if(a!==void 0)return a}},has(n,r,i){for(const o of t){const s=o();if(r in s)return!0}return!1}};return new Proxy({},e)}function uw(t){return W(t)||me(t)||ai(t)}const cw="SAMPLE_FACET_UNIFORM",K0="SAMPLE_FACET_TEXTURE";class Wr{constructor(e){this.unitView=e,this.encoders=void 0,this.bufferInfo=void 0,this.programInfo=void 0,this.vertexArrayInfo=void 0,this.domainUniformInfo=void 0,this.viewUniformInfo=void 0,this.rangeMap=new lw,this.defaultProperties={get clip(){return["x","y"].map(n=>e.getScaleResolution(n)).some(n=>(n==null?void 0:n.isZoomable())??!1)},xOffset:0,yOffset:0,minBufferSize:0},this.properties=aw(typeof this.unitView.spec.mark=="object"?()=>this.unitView.spec.mark:()=>({}),()=>this.defaultProperties)}get opaque(){return!1}getAttributes(){throw new Error("Not implemented!")}getSupportedChannels(){return["sample","facetIndex","x","y","color","opacity","search","uniqueId"]}getDefaultEncoding(){const e={sample:void 0,uniqueId:void 0};return this.isPickingParticipant()&&(e.uniqueId={field:"_uniqueId"}),e}fixEncoding(e){return e}get encoding(){return Ln(this,"encoding",()=>{const e=this.getDefaultEncoding(),n=this.unitView.getEncoding(),r=s=>{const a=this.properties[s];return uw(a)&&{value:a}},i=Object.fromEntries(this.getSupportedChannels().map(s=>[s,r(s)]).filter(s=>s[1].value!==void 0)),o=this.fixEncoding({...e,...i,...n});for(const s of Object.keys(o))this.getSupportedChannels().includes(s)||delete o[s];return o})}getContext(){return this.unitView.context}getType(){return this.unitView.getMarkType()}initializeData(){}initializeEncoders(){this.encoders=O1(this)}async initializeGraphics(){}updateGraphicsData(){}getSampleFacetMode(){if(this.encoders.facetIndex)return K0;if(this.unitView.getFacetAccessor())return cw}createAndLinkShaders(e,n,r=[]){const i=this.getAttributes();r.push("// view: "+this.unitView.getPathString()),this.domainUniforms=[];let o=[];const s=this.getSampleFacetMode();s&&r.push(`#define ${s}`);for(const h of i){let p;if(h in this.encoding)p=h;else continue;const d=this.encoding[p];if(d)if(Ge(d))o.push(zb(p,d.value));else{const g=Pe(d)&&d.resolutionChannel||p,m=this.unitView.getScaleResolution(g).getScale(),A=Ob(p,m,d);o.push(A.glsl),A.domainUniform&&this.domainUniforms.push(A.domainUniform)}}const a=this.domainUniforms.length?`layout(std140) uniform Domains {
+Error compiling: ${o}`,t.deleteShader(u));t.deleteProgram(r)}if(o)return{message:o,detail:s}}return{program:r,getProgramErrors:i}}function vo(t,e,n,r){return r?_f(t,r,n,e):r=Qr(t,{...e,src:n}),r}function aw(...t){const e={get(n,r,i){for(const o of t){const a=o()[r];if(a!==void 0)return a}},has(n,r,i){for(const o of t){const s=o();if(r in s)return!0}return!1}};return new Proxy({},e)}function uw(t){return W(t)||me(t)||ai(t)}const cw="SAMPLE_FACET_UNIFORM",K0="SAMPLE_FACET_TEXTURE";class Wr{constructor(e){this.unitView=e,this.encoders=void 0,this.bufferInfo=void 0,this.programInfo=void 0,this.vertexArrayInfo=void 0,this.domainUniformInfo=void 0,this.viewUniformInfo=void 0,this.rangeMap=new lw,this.defaultProperties={get clip(){return["x","y"].map(n=>e.getScaleResolution(n)).some(n=>(n==null?void 0:n.isZoomable())??!1)},xOffset:0,yOffset:0,minBufferSize:0},this.properties=aw(typeof this.unitView.spec.mark=="object"?()=>this.unitView.spec.mark:()=>({}),()=>this.defaultProperties)}get opaque(){return!1}getAttributes(){throw new Error("Not implemented!")}getSupportedChannels(){return["sample","facetIndex","x","y","color","opacity","search","uniqueId"]}getDefaultEncoding(){const e={sample:void 0,uniqueId:void 0};return this.isPickingParticipant()&&(e.uniqueId={field:"_uniqueId"}),e}fixEncoding(e){return e}get encoding(){return Ln(this,"encoding",()=>{const e=this.getDefaultEncoding(),n=this.unitView.getEncoding(),r=s=>{const a=this.properties[s];return uw(a)&&{value:a}},i=Object.fromEntries(this.getSupportedChannels().map(s=>[s,r(s)]).filter(s=>s[1].value!==void 0)),o=this.fixEncoding({...e,...i,...n});for(const s of Object.keys(o))this.getSupportedChannels().includes(s)||delete o[s];return o})}getContext(){return this.unitView.context}getType(){return this.unitView.getMarkType()}initializeData(){}initializeEncoders(){this.encoders=O1(this)}async initializeGraphics(){}updateGraphicsData(){}getSampleFacetMode(){if(this.encoders.facetIndex)return K0;if([...this.unitView.getAncestors()].find(e=>"samples"in e.spec))return cw}createAndLinkShaders(e,n,r=[]){const i=this.getAttributes();r.push("// view: "+this.unitView.getPathString()),this.domainUniforms=[];let o=[];const s=this.getSampleFacetMode();s&&r.push(`#define ${s}`);for(const h of i){let p;if(h in this.encoding)p=h;else continue;const d=this.encoding[p];if(d)if(Ge(d))o.push(zb(p,d.value));else{const g=Pe(d)&&d.resolutionChannel||p,m=this.unitView.getScaleResolution(g).getScale(),A=Ob(p,m,d);o.push(A.glsl),A.domainUniform&&this.domainUniforms.push(A.domainUniform)}}const a=this.domainUniforms.length?`layout(std140) uniform Domains {
 `+this.domainUniforms.map(h=>`    ${h}
 `).join("")+`};
 
 `:"",c=[`precision highp float;
-`,...r,j0,Jb,a,...o,_b,$b,e],f=[...r,j0,ew,n],l=this.gl;this.programStatus=sw(l,this.glHelper.compileShader(l.VERTEX_SHADER,c),this.glHelper.compileShader(l.FRAGMENT_SHADER,f))}finalizeGraphicsInitialization(){const e=this.programStatus.getProgramErrors();if(e){e.detail&&console.warn(e.detail);const n=new Error("Cannot create shader program: "+e.message);throw n.view=this.unitView,n}this.programInfo=cb(this.gl,this.programStatus.program),delete this.programStatus,this.domainUniforms.length&&(this.domainUniformInfo=S0(this.gl,this.programInfo,"Domains")),this.viewUniformInfo=S0(this.gl,this.programInfo,"View"),this.gl.useProgram(this.programInfo.program),this._setDatums(),Ee(this.programInfo,{uSampleFacet:[0,1,0,1],uTransitionOffset:0})}_setDatums(){for(const[e,n]of Object.entries(this.encoding))if(Rr(n)){const r=this.encoders[e],i=r.indexer?r.indexer(n.datum):yo(r.scale.type)?Qa(+n.datum):+n.datum;Ee(this.programInfo,{[Ga+e]:i})}}deleteGraphicsData(){if(this.bufferInfo){const e=this.gl;for(let n=0;n<8;n++)e.disableVertexAttribArray(n);Object.values(this.bufferInfo.attribs).forEach(n=>this.gl.deleteBuffer(n.buffer)),this.bufferInfo.indices&&this.gl.deleteBuffer(this.bufferInfo.indices),this.bufferInfo=void 0}}updateBufferInfo(e){if(this.gl.bindVertexArray(null),this.bufferInfo&&e.vertexCount<=this.bufferInfo.allocatedVertices)for(const[n,r]of Object.entries(e.arrays))r.data&&wx(this.gl,this.bufferInfo.attribs[n],r.data,0);else this.deleteGraphicsData(),this.bufferInfo=Ex(this.gl,e.arrays,{numElements:e.vertexCount}),this.bufferInfo.allocatedVertices=e.allocatedVertices,this.vertexArrayInfo=void 0}get glHelper(){return this.getContext().glHelper}get gl(){return this.glHelper.gl}onBeforeSampleAnimation(){}onAfterSampleAnimation(){}isReady(){return this.bufferInfo&&this.programInfo}isPickingParticipant(){if(this.properties.tooltip===null)return!1;for(const e of this.unitView.getAncestors())if(!e.isPickingSupported())return!1;return!0}prepareRender(e){const n=this.glHelper,r=this.gl,i=[];if(i.push(()=>{this.vertexArrayInfo||(this.vertexArrayInfo=Fb(this.gl,this.programInfo,this.bufferInfo)),r.useProgram(this.programInfo.program)}),this.domainUniformInfo){for(const[s,a]of Object.entries(this.domainUniformInfo.setters)){const u=s.substring(z0.length),c=this.encoding[u],f=Pe(c)&&c.resolutionChannel||u,l=this.unitView.getScaleResolution(f);if(l){const h=l.getScale();i.push(()=>{const p=Yt(h.type)?[0,h.domain().length]:h.domain();a(yo(h.type)?Hb(p):p)})}}i.push(()=>D0(r,this.programInfo,this.domainUniformInfo))}for(const[s,a]of Object.entries(this.encoding))if(Pe(a)){const u=Pe(a)&&a.resolutionChannel||s,c=this.unitView.getScaleResolution(u),f=n.rangeTextures.get(c);f&&i.push(()=>Ee(this.programInfo,{[Ua+s]:f}))}this.getSampleFacetMode()==K0&&i.push(()=>{let s;for(const a of this.unitView.getAncestors())if(s=a.getSampleFacetTexture(),s)break;if(!s)throw new Error("No facet texture available. This is bug.");Ee(this.programInfo,{uSampleFacetTexture:s})});const o=(e.picking??!1)&&this.isPickingParticipant();return i.push(()=>B0(this.viewUniformInfo,{uViewOpacity:this.unitView.getEffectiveOpacity(),uPickingEnabled:o})),this.opaque||e.picking?i.push(()=>r.disable(r.BLEND)):i.push(()=>r.enable(r.BLEND)),i}prepareSampleFacetRendering(e){const n=e.sampleFacetRenderingOptions,r=this.programInfo.uniformSetters.uSampleFacet;if(n&&r){const i=n.locSize?n.locSize.location:0,o=n.locSize?n.locSize.size:1;if(i>1||i+o<0)return!1;const s=n.targetLocSize?n.targetLocSize.location:i,a=n.targetLocSize?n.targetLocSize.size:o;this.gl.uniform4f(r.location,i,o,s,a)}return!0}render(e){}createRenderCallback(e,n){var f;const r=this;let i;const o=(f=this.unitView.getScaleResolution("x"))==null?void 0:f.getScale(),s=o&&Te(o.type),a=["index","locus"].includes(o==null?void 0:o.type)?-1:0,u=[0,0];i=l=>{if(s&&l.xIndex){const h=o.domain(),p=l.xIndex(h[0]+a,h[1],u),d=p[0],g=p[1]-d;g>0&&e(d,g)}else e(l.offset,l.count)};const c=this.rangeMap.get(n.facetId);return n.sampleFacetRenderingOptions?function(){c.count&&r.prepareSampleFacetRendering(n)&&i(c)}:function(){c.count&&i(c)}}setViewport(e,n){const r=this.glHelper.dpr,i=this.gl,o=this.properties,s=this.glHelper.getLogicalCanvasSize(),a=.5,u=(o.xOffset||0)+a,c=(o.yOffset||0)+a;let f,l=e;if(o.clip||n){let h=0,p=0,d;n?(l=o.clip?e.intersect(n):n,d=[e.width/l.width,e.height/l.height],p=Math.max(0,e.y2-n.y2),h=Math.max(0,e.x2-n.x2)):d=[1,1];const g=[e.x,s.height-l.y2,Math.max(0,l.width),Math.max(0,l.height)].map(b=>b*r),m=g.map(b=>Math.floor(b)),[A,y]=g.map((b,C)=>b-m[C]);i.viewport(...m),i.scissor(...m),i.enable(i.SCISSOR_TEST),f={uViewOffset:[(u+h+A)/l.width,-(c+p-y)/l.height],uViewScale:d}}else i.viewport(0,0,s.width*r,s.height*r),i.disable(i.SCISSOR_TEST),f={uViewOffset:[(e.x+u)/s.width,(s.height-e.y-c-e.height)/s.height],uViewScale:[e.width/s.width,e.height/s.height]};return B0(this.viewUniformInfo,{...f,uViewportSize:[e.width,e.height],uDevicePixelRatio:this.glHelper.dpr}),D0(this.gl,this.programInfo,this.viewUniformInfo),l.height>0&&l.width>0}findDatumAt(e,n){}}class lw extends Tt{constructor(){super([],JSON.stringify)}get(e){let n=super.get(e);return n===void 0&&(n={offset:0,count:0,xIndex:void 0},super.set(e,n)),n}migrateEntries(e){for(const[n,r]of e.entries())Object.assign(this.get(n),r)}}function Ya(t,e){const n=Q1(e);let r=t[e]&&{...t[e]},i=t[n]&&{...t[n]};if(!(Ge(r)||Ge(i))){if(r){if(!Pe(t[e]))return;if(i){if(r.type!="quantitative"){const o=(1-(r.band||1))/2;r.band=o,i.band=-o}}else if(r.type=="quantitative")i={datum:0};else{i={...r};const o=(1-(r.band??1))/2;r.band=0+o,i.band=1-o}}else r={value:0},i={value:1};t[e]=r,t[n]=i}}function q0(t,e){t.stroke||(e?t.stroke={value:null}:t.stroke={resolutionChannel:"color",...t.color}),Ge(t.stroke)&&t.stroke.value===null&&(t.strokeWidth={value:0}),t.strokeOpacity||(t.strokeOpacity={resolutionChannel:"opacity",...t.opacity})}function J0(t,e){Ge(t.fill)&&t.fill.value===null?t.fillOpacity={value:0}:t.fill||(t.fill={resolutionChannel:"color",...t.color},!e&&!t.fillOpacity&&(t.fillOpacity={value:0})),t.fillOpacity||(e?t.fillOpacity={resolutionChannel:"opacity",...t.opacity}:t.fillOpacity={value:0})}class fw extends Wr{constructor(e){super(e),Object.defineProperties(this.defaultProperties,Object.getOwnPropertyDescriptors({x2:void 0,y2:void 0,filled:!0,color:"#4c78a8",opacity:1,strokeWidth:3,cornerRadius:0,minWidth:.5,minHeight:.5,minOpacity:1,tessellationZoomThreshold:10,tessellationTiles:35}))}getAttributes(){return["uniqueId","facetIndex","x","x2","y","y2","fill","stroke","fillOpacity","strokeOpacity","strokeWidth"]}getSupportedChannels(){return[...super.getSupportedChannels(),"x2","y2","fill","stroke","fillOpacity","strokeOpacity","strokeWidth"]}get opaque(){return Ln(this,"opaque",()=>!this._isRoundedCorners()&&!this._isStroked()&&Ge(this.encoding.fillOpacity)&&this.encoding.fillOpacity.value==1&&this.properties.minOpacity==1)&&this.unitView.getEffectiveOpacity()==1}fixEncoding(e){return Ya(e,"x"),Ya(e,"y"),q0(e,this.properties.filled),J0(e,this.properties.filled),delete e.color,delete e.opacity,e}onBeforeSampleAnimation(){}onAfterSampleAnimation(){}_isRoundedCorners(){return["","TopLeft","TopRight","BottomLeft","BottomRight"].map(e=>"cornerRadius"+e).some(e=>this.properties[e]>0)}_isStroked(){const e=this.encoding.strokeWidth;return!(Ge(e)&&!e.value)}async initializeGraphics(){await super.initializeGraphics();const e=[];this._isRoundedCorners()&&e.push("ROUNDED_CORNERS"),this._isStroked()&&e.push("STROKED"),this.createAndLinkShaders(Rb,Lb,e.map(n=>"#define "+n))}finalizeGraphicsInitialization(){super.finalizeGraphicsInitialization(),this.gl.useProgram(this.programInfo.program);const e=this.properties;Ee(this.programInfo,{uMinSize:[e.minWidth,e.minHeight],uMinOpacity:e.minOpacity,uCornerRadii:[e.cornerRadiusTopRight??e.cornerRadius,e.cornerRadiusBottomRight??e.cornerRadius,e.cornerRadiusTopLeft??e.cornerRadius,e.cornerRadiusBottomLeft??e.cornerRadius]})}updateGraphicsData(){const e=this.unitView.getCollector(),n=e.getItemCount(),r=new Wb({encoders:this.encoders,attributes:this.getAttributes(),numItems:n});r.addBatches(e.facetBatches);const i=r.toArrays();this.rangeMap.migrateEntries(i.rangeMap),this.updateBufferInfo(i)}prepareRender(e){const n=super.prepareRender(e);return n.push(()=>Pn(this.gl,this.programInfo,this.vertexArrayInfo)),n}render(e){const n=this.gl;return this.createRenderCallback((r,i)=>{jr(n,this.vertexArrayInfo,n.TRIANGLE_STRIP,i,r)},e)}findDatumAt(e,n){e=Ke(e);const r=this.encoders,i=this.unitView.getCollector().facetBatches.get(e),o=r.x.accessor,s=r.x2.accessor;if(i)return i.find(a=>n>=o(a)&&n<s(a))}}const hw=`/***The stroke should only grow inwards,e.g,the diameter/outline is not affected by the stroke width.*Thus,a point that has a zero size has no visible stroke. This allows strokes to be used with*geometric zoom,etc.*/uniform bool uInwardStroke;uniform lowp float uMaxRelativePointDiameter;uniform float uScaleFactor;uniform float uMaxPointSize;uniform float uZoomLevel;uniform float uSemanticThreshold;out float vRadius;out float vRadiusWithPadding;out lowp vec4 vFillColor;out lowp vec4 vStrokeColor;out lowp float vShape;out lowp float vHalfStrokeWidth;out mat2 vRotationMatrix;float computeSemanticThresholdFactor(){return getScaled_semanticScore()>=uSemanticThreshold ? 1.0 : 0.0;}/***Computes a scaling factor for the points in a sample-faceted view.*/float getDownscaleFactor(vec2 pos){if(!isFacetedSamples()){return 1.0;}float sampleFacetHeight=getSampleFacetHeight(pos);float maxPointDiameter=sqrt(uMaxPointSize);float factor=sampleFacetHeight*uViewportSize.y*uMaxRelativePointDiameter;return clamp(0.0,maxPointDiameter,factor)/maxPointDiameter;}vec2 getDxDy(){
+`,...r,j0,Jb,a,...o,_b,$b,e],f=[...r,j0,ew,n],l=this.gl;this.programStatus=sw(l,this.glHelper.compileShader(l.VERTEX_SHADER,c),this.glHelper.compileShader(l.FRAGMENT_SHADER,f))}finalizeGraphicsInitialization(){const e=this.programStatus.getProgramErrors();if(e){e.detail&&console.warn(e.detail);const n=new Error("Cannot create shader program: "+e.message);throw n.view=this.unitView,n}this.programInfo=cb(this.gl,this.programStatus.program),delete this.programStatus,this.domainUniforms.length&&(this.domainUniformInfo=S0(this.gl,this.programInfo,"Domains")),this.viewUniformInfo=S0(this.gl,this.programInfo,"View"),this.gl.useProgram(this.programInfo.program),this._setDatums(),Ee(this.programInfo,{uSampleFacet:[0,1,0,1],uTransitionOffset:0})}_setDatums(){for(const[e,n]of Object.entries(this.encoding))if(Rr(n)){const r=this.encoders[e],i=r.indexer?r.indexer(n.datum):yo(r.scale.type)?Qa(+n.datum):+n.datum;Ee(this.programInfo,{[Ga+e]:i})}}deleteGraphicsData(){if(this.bufferInfo){const e=this.gl;for(let n=0;n<8;n++)e.disableVertexAttribArray(n);Object.values(this.bufferInfo.attribs).forEach(n=>this.gl.deleteBuffer(n.buffer)),this.bufferInfo.indices&&this.gl.deleteBuffer(this.bufferInfo.indices),this.bufferInfo=void 0}}updateBufferInfo(e){if(this.gl.bindVertexArray(null),this.bufferInfo&&e.vertexCount<=this.bufferInfo.allocatedVertices)for(const[n,r]of Object.entries(e.arrays))r.data&&wx(this.gl,this.bufferInfo.attribs[n],r.data,0);else this.deleteGraphicsData(),this.bufferInfo=Ex(this.gl,e.arrays,{numElements:e.vertexCount}),this.bufferInfo.allocatedVertices=e.allocatedVertices,this.vertexArrayInfo=void 0}get glHelper(){return this.getContext().glHelper}get gl(){return this.glHelper.gl}onBeforeSampleAnimation(){}onAfterSampleAnimation(){}isReady(){return this.bufferInfo&&this.programInfo}isPickingParticipant(){if(this.properties.tooltip===null)return!1;for(const e of this.unitView.getAncestors())if(!e.isPickingSupported())return!1;return!0}prepareRender(e){const n=this.glHelper,r=this.gl,i=[];if(i.push(()=>{this.vertexArrayInfo||(this.vertexArrayInfo=Fb(this.gl,this.programInfo,this.bufferInfo)),r.useProgram(this.programInfo.program)}),this.domainUniformInfo){for(const[s,a]of Object.entries(this.domainUniformInfo.setters)){const u=s.substring(z0.length),c=this.encoding[u],f=Pe(c)&&c.resolutionChannel||u,l=this.unitView.getScaleResolution(f);if(l){const h=l.getScale();i.push(()=>{const p=Yt(h.type)?[0,h.domain().length]:h.domain();a(yo(h.type)?Hb(p):p)})}}i.push(()=>D0(r,this.programInfo,this.domainUniformInfo))}for(const[s,a]of Object.entries(this.encoding))if(Pe(a)){const u=Pe(a)&&a.resolutionChannel||s,c=this.unitView.getScaleResolution(u),f=n.rangeTextures.get(c);f&&i.push(()=>Ee(this.programInfo,{[Ua+s]:f}))}this.getSampleFacetMode()==K0&&i.push(()=>{let s;for(const a of this.unitView.getAncestors())if(s=a.getSampleFacetTexture(),s)break;if(!s)throw new Error("No facet texture available. This is bug.");Ee(this.programInfo,{uSampleFacetTexture:s})});const o=(e.picking??!1)&&this.isPickingParticipant();return i.push(()=>B0(this.viewUniformInfo,{uViewOpacity:this.unitView.getEffectiveOpacity(),uPickingEnabled:o})),this.opaque||e.picking?i.push(()=>r.disable(r.BLEND)):i.push(()=>r.enable(r.BLEND)),i}prepareSampleFacetRendering(e){const n=e.sampleFacetRenderingOptions,r=this.programInfo.uniformSetters.uSampleFacet;if(n&&r){const i=n.locSize?n.locSize.location:0,o=n.locSize?n.locSize.size:1;if(i>1||i+o<0)return!1;const s=n.targetLocSize?n.targetLocSize.location:i,a=n.targetLocSize?n.targetLocSize.size:o;this.gl.uniform4f(r.location,i,o,s,a)}return!0}render(e){}createRenderCallback(e,n){var l;const r=this;let i;const o=(l=this.unitView.getScaleResolution("x"))==null?void 0:l.getScale(),s=o&&Te(o.type),a=["index","locus"].includes(o==null?void 0:o.type)?-1:0,u=[0,0];i=h=>{if(s&&h.xIndex){const p=o.domain(),d=h.xIndex(p[0]+a,p[1],u),g=d[0],m=d[1]-g;m>0&&e(g,m)}else e(h.offset,h.count)};const c=this.rangeMap.get(void 0).count==0?n.facetId:void 0,f=this.rangeMap.get(c);return n.sampleFacetRenderingOptions?function(){f.count&&r.prepareSampleFacetRendering(n)&&i(f)}:function(){f.count&&i(f)}}setViewport(e,n){const r=this.glHelper.dpr,i=this.gl,o=this.properties,s=this.glHelper.getLogicalCanvasSize(),a=.5,u=(o.xOffset||0)+a,c=(o.yOffset||0)+a;let f,l=e;if(o.clip||n){let h=0,p=0,d;n?(l=o.clip?e.intersect(n):n,d=[e.width/l.width,e.height/l.height],p=Math.max(0,e.y2-n.y2),h=Math.max(0,e.x2-n.x2)):d=[1,1];const g=[e.x,s.height-l.y2,Math.max(0,l.width),Math.max(0,l.height)].map(b=>b*r),m=g.map(b=>Math.floor(b)),[A,y]=g.map((b,C)=>b-m[C]);i.viewport(...m),i.scissor(...m),i.enable(i.SCISSOR_TEST),f={uViewOffset:[(u+h+A)/l.width,-(c+p-y)/l.height],uViewScale:d}}else i.viewport(0,0,s.width*r,s.height*r),i.disable(i.SCISSOR_TEST),f={uViewOffset:[(e.x+u)/s.width,(s.height-e.y-c-e.height)/s.height],uViewScale:[e.width/s.width,e.height/s.height]};return B0(this.viewUniformInfo,{...f,uViewportSize:[e.width,e.height],uDevicePixelRatio:this.glHelper.dpr}),D0(this.gl,this.programInfo,this.viewUniformInfo),l.height>0&&l.width>0}findDatumAt(e,n){}}class lw extends Tt{constructor(){super([],JSON.stringify)}get(e){let n=super.get(e);return n===void 0&&(n={offset:0,count:0,xIndex:void 0},super.set(e,n)),n}migrateEntries(e){for(const[n,r]of e.entries())Object.assign(this.get(n),r)}}function Ya(t,e){const n=Q1(e);let r=t[e]&&{...t[e]},i=t[n]&&{...t[n]};if(!(Ge(r)||Ge(i))){if(r){if(!Pe(t[e]))return;if(i){if(r.type!="quantitative"){const o=(1-(r.band||1))/2;r.band=o,i.band=-o}}else if(r.type=="quantitative")i={datum:0};else{i={...r};const o=(1-(r.band??1))/2;r.band=0+o,i.band=1-o}}else r={value:0},i={value:1};t[e]=r,t[n]=i}}function q0(t,e){t.stroke||(e?t.stroke={value:null}:t.stroke={resolutionChannel:"color",...t.color}),Ge(t.stroke)&&t.stroke.value===null&&(t.strokeWidth={value:0}),t.strokeOpacity||(t.strokeOpacity={resolutionChannel:"opacity",...t.opacity})}function J0(t,e){Ge(t.fill)&&t.fill.value===null?t.fillOpacity={value:0}:t.fill||(t.fill={resolutionChannel:"color",...t.color},!e&&!t.fillOpacity&&(t.fillOpacity={value:0})),t.fillOpacity||(e?t.fillOpacity={resolutionChannel:"opacity",...t.opacity}:t.fillOpacity={value:0})}class fw extends Wr{constructor(e){super(e),Object.defineProperties(this.defaultProperties,Object.getOwnPropertyDescriptors({x2:void 0,y2:void 0,filled:!0,color:"#4c78a8",opacity:1,strokeWidth:3,cornerRadius:0,minWidth:.5,minHeight:.5,minOpacity:1,tessellationZoomThreshold:10,tessellationTiles:35}))}getAttributes(){return["uniqueId","facetIndex","x","x2","y","y2","fill","stroke","fillOpacity","strokeOpacity","strokeWidth"]}getSupportedChannels(){return[...super.getSupportedChannels(),"x2","y2","fill","stroke","fillOpacity","strokeOpacity","strokeWidth"]}get opaque(){return Ln(this,"opaque",()=>!this._isRoundedCorners()&&!this._isStroked()&&Ge(this.encoding.fillOpacity)&&this.encoding.fillOpacity.value==1&&this.properties.minOpacity==1)&&this.unitView.getEffectiveOpacity()==1}fixEncoding(e){return Ya(e,"x"),Ya(e,"y"),q0(e,this.properties.filled),J0(e,this.properties.filled),delete e.color,delete e.opacity,e}onBeforeSampleAnimation(){}onAfterSampleAnimation(){}_isRoundedCorners(){return["","TopLeft","TopRight","BottomLeft","BottomRight"].map(e=>"cornerRadius"+e).some(e=>this.properties[e]>0)}_isStroked(){const e=this.encoding.strokeWidth;return!(Ge(e)&&!e.value)}async initializeGraphics(){await super.initializeGraphics();const e=[];this._isRoundedCorners()&&e.push("ROUNDED_CORNERS"),this._isStroked()&&e.push("STROKED"),this.createAndLinkShaders(Rb,Lb,e.map(n=>"#define "+n))}finalizeGraphicsInitialization(){super.finalizeGraphicsInitialization(),this.gl.useProgram(this.programInfo.program);const e=this.properties;Ee(this.programInfo,{uMinSize:[e.minWidth,e.minHeight],uMinOpacity:e.minOpacity,uCornerRadii:[e.cornerRadiusTopRight??e.cornerRadius,e.cornerRadiusBottomRight??e.cornerRadius,e.cornerRadiusTopLeft??e.cornerRadius,e.cornerRadiusBottomLeft??e.cornerRadius]})}updateGraphicsData(){const e=this.unitView.getCollector(),n=e.getItemCount(),r=new Wb({encoders:this.encoders,attributes:this.getAttributes(),numItems:n});r.addBatches(e.facetBatches);const i=r.toArrays();this.rangeMap.migrateEntries(i.rangeMap),this.updateBufferInfo(i)}prepareRender(e){const n=super.prepareRender(e);return n.push(()=>Pn(this.gl,this.programInfo,this.vertexArrayInfo)),n}render(e){const n=this.gl;return this.createRenderCallback((r,i)=>{jr(n,this.vertexArrayInfo,n.TRIANGLE_STRIP,i,r)},e)}findDatumAt(e,n){e=Ke(e);const r=this.encoders,i=this.unitView.getCollector().facetBatches.get(e),o=r.x.accessor,s=r.x2.accessor;if(i)return i.find(a=>n>=o(a)&&n<s(a))}}const hw=`/***The stroke should only grow inwards,e.g,the diameter/outline is not affected by the stroke width.*Thus,a point that has a zero size has no visible stroke. This allows strokes to be used with*geometric zoom,etc.*/uniform bool uInwardStroke;uniform lowp float uMaxRelativePointDiameter;uniform float uScaleFactor;uniform float uMaxPointSize;uniform float uZoomLevel;uniform float uSemanticThreshold;out float vRadius;out float vRadiusWithPadding;out lowp vec4 vFillColor;out lowp vec4 vStrokeColor;out lowp float vShape;out lowp float vHalfStrokeWidth;out mat2 vRotationMatrix;float computeSemanticThresholdFactor(){return getScaled_semanticScore()>=uSemanticThreshold ? 1.0 : 0.0;}/***Computes a scaling factor for the points in a sample-faceted view.*/float getDownscaleFactor(vec2 pos){if(!isFacetedSamples()){return 1.0;}float sampleFacetHeight=getSampleFacetHeight(pos);float maxPointDiameter=sqrt(uMaxPointSize);float factor=sampleFacetHeight*uViewportSize.y*uMaxRelativePointDiameter;return clamp(0.0,maxPointDiameter,factor)/maxPointDiameter;}vec2 getDxDy(){
 #if defined(dx_DEFINED) || defined(dy_DEFINED)
 return vec2(getScaled_dx(),getScaled_dy())/uViewportSize;
 #else
@@ -144,7 +144,7 @@ if(scale<1.0){if(uSqueeze){vec2 scaleFadeExtent=vec2(3.0,6.0)/size;if(scale<scal
  * All rights reserved.
  *
  * BSD-3-Clause License: https://github.com/vega/vega-lite/blob/master/LICENSE
- */const Ww="locus",Xw="index";var Zw=5;function Kw(t){const e=t.type;return!t.bins&&(e===yn||e===br||e===wr)}function uh(t){return Te(t)&&![Ze,Xw,Ww].includes(t)}function ch(t){return t||{warn:(e,...n)=>console.warn(e,...n)}}var qw=li(["set","modified","clear","type","scheme","schemeExtent","schemeCount","domain","domainMin","domainMid","domainMax","domainRaw","domainImplicit","nice","zero","bins","range","rangeStep","round","reverse","interpolate","interpolateGamma","zoom","fp64","name"]);function lh(t,e,n){n=ch(n);for(const r in t)if(!qw[r]){if(r==="padding"&&uh(e.type))continue;ge(e[r])?e[r](t[r]):n.warn("Unsupported scale property: "+r)}iv(e,t,rv(e,t,ev(e,t,n)))}function Jw(t,e){const n=_w(t),r=N(n);if(!r)throw new Error("Unknown scale type: "+n);const i=r();return lh(t,i,e),i}function _w(t){var e=t.type,n="",r;return e===Ze?Ze+"-"+yn:($w(t)&&(r=t.rawDomain?t.rawDomain.length:t.domain?t.domain.length+ +(t.domainMid!=null):0,n=r===2?Ze+"-":r===3?bn+"-":""),(n+e||yn).toLowerCase())}function $w(t){const e=t.type;return Te(e)&&e!==Vl&&e!==Yl&&(t.scheme||t.range&&t.range.length&&t.range.every(W))}function ev(t,e,n){if(!t.domain)return 0;n=ch(n);var r=tv(t,e.domainRaw,n);if(r>-1)return r;var i=e.domain,o=t.type,s=e.zero||e.zero===void 0&&Kw(t),a,u;return i?(uh(o)&&e.padding&&i[0]!==ke(i)&&(i=nv(o,i,e.range,e.padding,e.exponent,e.constant)),(s||e.domainMin!=null||e.domainMax!=null||e.domainMid!=null)&&(a=(i=i.slice()).length-1||1,s&&(i[0]>0&&(i[0]=0),i[a]<0&&(i[a]=0)),e.domainMin!=null&&(i[0]=e.domainMin),e.domainMax!=null&&(i[a]=e.domainMax),e.domainMid!=null&&(u=e.domainMid,(u<i[0]||u>i[a])&&n.warn("Scale domainMid exceeds domain min or max.",u),i.splice(a,0,u))),t.domain(fh(o,i,n)),o===Xs&&t.unknown(e.domainImplicit?ps:void 0),e.nice&&t.nice&&t.nice(e.nice!==!0&&sh(t,e.nice)||null),i.length):0}function tv(t,e,n){return e?(t.domain(fh(t.type,e,n)),e.length):-1}function nv(t,e,n,r,i,o){var s=Math.abs(ke(n)-n[0]),a=s/(s-2*r),u=t===yt?xu(e,null,a):t===wr?Po(e,null,a,.5):t===br?Po(e,null,a,i||1):t===Ui?dd(e,null,a,o||1):Au(e,null,a);return e=e.slice(),e[0]=u[0],e[e.length-1]=u[1],e}function fh(t,e,n){if(_l(t)){var r=Math.abs(e.reduce(function(i,o){return i+(o<0?-1:o>0?1:0)},0));r!==e.length&&n.warn("Log scale domain includes zero: "+ci(e))}return e}function rv(t,e,n){let r=e.bins;if(r&&!Fe(r)){const i=(r.start==null||r.stop==null)&&t.domain(),o=r.start==null?i[0]:r.start,s=r.stop==null?ke(i):r.stop,a=r.step;a||Y("Scale bins parameter missing step property."),r=Kn(o,s+a,a)}return r?t.bins=r:t.bins&&delete t.bins,t.type===Ks&&(r?!e.domain&&!e.domainRaw&&(t.domain(r),n=r.length):t.bins=t.domain()),n}function iv(t,e,n){var r=t.type,i=e.round||!1,o=e.range;if(e.rangeStep!=null)o=ov(r,e,n);else if(e.scheme&&(o=sv(r,e,n),ge(o))){if(t.interpolator)return t.interpolator(o);Y(`Scale type ${r} does not support interpolating color schemes.`)}if(o&&Qi(r))return t.interpolator(ji(Za(o,e.reverse),e.interpolate,e.interpolateGamma));o&&e.interpolate&&t.interpolate?t.interpolate($l(e.interpolate,e.interpolateGamma)):ge(t.round)?t.round(i):ge(t.rangeRound)&&t.interpolate(i?xr:At),o&&t.range(Za(o,e.reverse))}function ov(t,e,n){t!==Zl&&t!==Zs&&Y("Only band and point scales support rangeStep.");var r=(e.paddingOuter!=null?e.paddingOuter:e.padding)||0,i=t===Zs?1:(e.paddingInner!=null?e.paddingInner:e.padding)||0;return[0,e.rangeStep*Ys(n,i,r)]}function sv(t,e,n){var r=e.schemeExtent,i,o;return Fe(e.scheme)?o=ji(e.scheme,e.interpolate,e.interpolateGamma):(i=e.scheme.toLowerCase(),o=Js(i),o||Y(`Unrecognized scheme name: ${e.scheme}`)),n=t===Xl?n+1:t===Ks?n-1:t===Ws||t===Wl?+e.schemeCount||Zw:n,Qi(t)?hh(o,r,e.reverse):ge(o)?mA(hh(o,r),n):t===Xs?o:o.slice(0,n)}function hh(t,e,n){return ge(t)&&(e||n)?gA(t,Za(e||[0,1],n)):t}function Za(t,e){return e?t.slice().reverse():t}const dh=oe(",d");function av(t,e){return t.chrom+":"+dh(Math.floor(t.pos+1))+"-"+(t.chrom!=e.chrom?e.chrom+":":"")+dh(Math.ceil(e.pos))}const uv="https://genomespy.app/data/genomes/";class cv{constructor(e){if(this.config=e,!this.config.contigs&&typeof this.config.name!="string")throw new Error("No name has been defined for the genome assembly!");this.chromosomes=[],this.cumulativeChromPositions=new Map,this.chromosomesByName=new Map,this.startByIndex=[],this.totalSize=0,this.config.contigs&&this.setChromSizes(this.config.contigs)}get name(){return this.config.name}async load(e){if(!this.config.contigs){this.config.baseUrl?this.baseUrl=/^http(s)?/.test(this.config.baseUrl)?this.config.baseUrl:e+"/"+this.config.baseUrl:this.baseUrl=uv;try{this.setChromSizes(lv(await Si({baseURL:this.baseUrl}).load(`${this.config.name}/${this.name}.chrom.sizes`)))}catch(n){throw new Error(`Could not load chrom sizes: ${n.message}`)}}}setChromSizes(e){let n=0;this.startByIndex=[0];for(let r=0;r<e.length;r++){this.startByIndex.push(n);const i=e[r].size,o={...e[r],continuousStart:n,continuousEnd:n+i,continuousInterval:[n,n+i],index:r,number:r+1,odd:!(r&1)};this.chromosomes.push(o);const s=o.name.replace(/^chr/i,"");for(const a of["chr"+s,"CHR"+s,"Chr"+s,o.number,""+o.number,s,o.name])this.cumulativeChromPositions.set(a,n),this.chromosomesByName.set(a,o);n+=o.size}this.totalSize=n}getExtent(){return[0,this.totalSize]}toContinuous(e,n){let r=this.cumulativeChromPositions.get(e);if(r===void 0)throw new Error("Unknown chromosome/contig: "+e);return r+ +n}toChromosome(e){if(e>=this.totalSize)return;e=Math.floor(e);const n=sn(this.startByIndex,e)-1;if(n>0&&n<=this.chromosomes.length)return this.chromosomes[n-1]}toChromosomal(e){const n=this.toChromosome(e);if(n)return{chrom:n.name,pos:Math.floor(e)-n.continuousStart}}getChromosome(e){return this.chromosomesByName.get(e)}formatInterval(e){return av(...this.toChromosomalInterval(e))}toChromosomalInterval(e){const n=this.toChromosomal(e[0]+.5),r=this.toChromosomal(e[1]-.5);return r.pos+=1,[n,r]}toContinuousInterval(e){var i;let[n,r]=e;return r||(r=n),[this.toContinuous(n.chrom,n.pos??0),this.toContinuous(r.chrom,r.pos??((i=this.chromosomesByName.get(r.chrom))==null?void 0:i.size))]}parseInterval(e){const n=e.match(/^(chr[0-9A-Z]+)(?::([0-9,]+)(?:-(?:(chr[0-9A-Z]+):)?([0-9,]+))?)?$/);if(n){const r=n[1];if(n.slice(2).every(a=>a===void 0)){const a=this.getChromosome(r);return a?[a.continuousStart,a.continuousEnd]:void 0}const i=n[3]||r,o=parseInt(n[2].replace(/,/g,"")),s=n[4]!==void 0?parseInt(n[4].replace(/,/g,"")):o;return[this.toContinuous(r,o-1),this.toContinuous(i,s)]}}}function lv(t){return Pd(t).filter(e=>/^chr[0-9A-Z]+$/.test(e[0])).map(([e,n])=>({name:e,size:parseInt(n)}))}function ph(t){return Le(t)&&"chrom"in t}function fv(t){return t.every(ph)}class Kr extends Array{constructor(){super(),this.type=void 0}extend(e){return this}extendAll(e){if(e instanceof Kr&&e.type!=this.type)throw new Error(`Cannot combine different types of domains: ${this.type} and ${e.type}`);for(const n of e)this.extend(n);return this}extendAllWithAccessor(e,n){for(const r of e)this.extend(n(r));return this}}class Ka extends Kr{constructor(){super(),this.type="quantitative"}extend(e){return e==null||Number.isNaN(e)?this:(e=+e,this.length?e<this[0]?this[0]=e:e>this[1]&&(this[1]=e):(this.push(e),this.push(e)),this)}}class gh extends Kr{constructor(){super(),this.type="ordinal",this.uniqueValues=new Set}extend(e){return e==null||Number.isNaN(e)?this:(this.uniqueValues.has(e)||(this.uniqueValues.add(e),this.push(e)),this)}}class mh extends gh{constructor(){super(),this.type="nominal"}}class hv extends Kr{constructor(e){super();let n=0;for(let r=1;r<e.length;r++)n+=Math.sign(e[r]-e[r-1]);if(Math.abs(n)!=e.length-1)throw new Error("Piecewise domain must be strictly increasing or decreasing: "+JSON.stringify(e));e.forEach(r=>this.push(r))}extend(e){if(this.includes(e))return this;throw new Error("Piecewise domains are immutable and cannot be unioned!")}}const Ah={quantitative:Ka,index:Ka,locus:Ka,nominal:mh,ordinal:gh};function xh(t,e){if(t=="quantitative"&&dv(e)){const n=new hv(e);return n.type=t,n}else if(Ah[t]){const n=new Ah[t];return n.type=t,e&&n.extendAll(e),n}throw new Error("Unknown type: "+t)}function dv(t){return t&&t.length>0&&t.length!=2&&t.every(e=>typeof e=="number")}function pv(t){return((t*=2)<=1?t*t:--t*(2-t)+1)/2}const yh="quantitative",bh="ordinal",wh="nominal",vh="locus",gv="index";class mv{constructor(e){this.channel=e,this.members=[],this.type=null,this._zoomExtent=void 0,this._domainListeners=new Set,this.name=void 0,this._scale=void 0}addEventListener(e,n){if(e!="domain")throw new Error("Unsupported event type: "+e);this._domainListeners.add(n)}removeEventListener(e,n){if(e!="domain")throw new Error("Unsupported event type: "+e);this._domainListeners.delete(n)}_notifyDomainListeners(){for(const e of this._domainListeners.values())e({type:"domain",scaleResolution:this})}pushUnitView(e,n){var s;const r=aa(e,n),i=r.type,o=(s=r==null?void 0:r.scale)==null?void 0:s.name;if(o){if(this.name!==void 0&&o!=this.name)throw new Error(`Shared scales have conflicting names: "${o}" vs. "${this.name}"!`);this.name=o}if(!this.type)this.type=i;else if(i!==this.type&&!Nr(n))throw new Error(`Can not use shared scale for different data types: ${this.type} vs. ${i}. Use "resolve: independent" for channel ${this.channel}`);this.members.push({view:e,channel:n})}isExplicitDomain(){return!!this.getConfiguredDomain()}_getMergedScaleProps(){return Ln(this,"mergedScaleProps",()=>{const e=this.members.map(n=>aa(n.view,n.channel).scale).filter(n=>n!==void 0);return Eo(e,"scale",["domain"])})}getScaleProps(){return Ln(this,"scaleProps",()=>{const e=this._getMergedScaleProps();if(e===null||e.type=="null")return{type:"null"};const n={...this._getDefaultScaleProperties(this.type),...e};n.type||(n.type=Av(this.channel,this.type));const r=this.getInitialDomain();return r&&r.length>0?n.domain=r:Yt(n.type)&&(n.domain=new mh),!n.domain&&n.domainMid!==void 0&&(n.domain=[n.domainMin??0,n.domainMax??1]),this.channel=="y"&&Yt(n.type)&&n.reverse==null&&(n.reverse=!0),n.range&&n.scheme&&delete n.scheme,!("zoom"in n)&&["index","locus"].includes(n.type)&&(n.zoom=!0),xv(n,this.channel),n})}getInitialDomain(){return this.getConfiguredDomain()??(this.type==vh?this.getGenome().getExtent():this.getDataDomain())}getConfiguredDomain(){return this._reduceDomains(e=>Nr(e.channel)?void 0:e.view.getConfiguredDomain(e.channel))}getDataDomain(){return this._reduceDomains(e=>Nr(e.channel)?void 0:e.view.extractDataDomain(e.channel))}reconfigure(){if(this._scale&&this._scale.type!="null"){V0(this,"scaleProps");const e=this.getScaleProps();lh(e,this._scale),Te(this._scale.type)&&(this._zoomExtent=this._getZoomExtent())}}getScale(){if(this._scale)return this._scale;const e=this.getScaleProps(),n=Jw(e);return this._scale=n,rm(n)&&n.genome(this.getGenome()),Te(n.type)&&(this._zoomExtent=this._getZoomExtent()),n}getDomain(){return this.getScale().domain()}getComplexDomain(){var e;return((e=this.getGenome())==null?void 0:e.toChromosomalInterval(this.getDomain()))??this.getDomain()}isZoomed(){return this.isZoomable()&&rf(this.getInitialDomain(),this.getDomain())}isZoomable(){if(!yf(this.channel))return!1;const e=this.getScale().type;return["linear","locus","index","log","pow","sqrt"].includes(e)?!!this.getScaleProps().zoom:!1}zoom(e,n,r){if(!this.isZoomable())return!1;const i=this.getScale(),o=i.domain();let s=[...o],a=i.invert(n);switch(this.getScaleProps().reverse&&(r=-r),"align"in i&&(a+=i.align()),i.type){case"linear":case"index":case"locus":s=ld(s,r||0),s=Au(s,a,e);break;case"log":s=fd(s,r||0),s=xu(s,a,e);break;case"pow":case"sqrt":{const u=i;s=hd(s,r||0,u.exponent()),s=Po(s,a,e,u.exponent());break}default:throw new Error("Zooming is not implemented for: "+i.type)}return this._zoomExtent&&(s=pd(s,this._zoomExtent[0],this._zoomExtent[1])),[0,1].some(u=>s[u]!=o[u])?(i.domain(s),this._notifyDomainListeners(),!0):!1}async zoomTo(e,n=!1){var a;if(ai(n)&&(n=n?700:0),!this.isZoomable())throw new Error("Not a zoomable scale!");const r=this.fromComplexInterval(e),i=(a=this.members[0])==null?void 0:a.view.context.animator,o=this.getScale(),s=o.domain();if(n>0&&s.length==2){const u=s[1]-s[0],c=s[0]+u/2,f=r[1]-r[0],l=r[0]+f/2,h=yl([c,0,u],[l,0,f]).rho(.7);await i.transition({duration:n/1e3*h.duration,easingFunction:pv,onUpdate:p=>{const[d,,g]=h(p);o.domain([d-g/2,d+g/2]),this._notifyDomainListeners()}}),o.domain(r),this._notifyDomainListeners()}else o.domain(r),i==null||i.requestRender(),this._notifyDomainListeners()}resetZoom(){if(!this.isZoomable())throw new Error("Not a zoomable scale!");const e=this.getDomain(),n=this.getInitialDomain();return[0,1].some(r=>n[r]!=e[r])?(this._scale.domain(n),this._notifyDomainListeners(),!0):!1}getZoomLevel(){return this.isZoomable()?ui(this._zoomExtent)/ui(this.getScale().domain()):1}_getZoomExtent(){const e=this.getScaleProps(),n=e.zoom;if(yv(n)&&Fe(n.extent))return this.fromComplexInterval(n.extent);if(n)return e.type=="locus"?this.getGenome().getExtent():this._scale.domain()}_getDefaultScaleProperties(e){const n=this.channel,r={};return this.isExplicitDomain()&&(r.zero=!1),kr(n)?r.nice=!this.isExplicitDomain():Kt(n)?r.scheme=e==wh?"tableau10":e==bh?"blues":"viridis":qi(n)?r.range=wf(n):n=="size"?r.range=[0,400]:n=="angle"&&(r.range=[0,360]),r}getGenome(){var n;if(this.type!=="locus")return;const e=(n=this.members[0].view.context.genomeStore)==null?void 0:n.getGenome();if(!e)throw new Error("No genome has been defined!");return e}invertToComplex(e){const n=this.getScale();if("invert"in n){const r=n.invert(e);return this.toComplex(r)}else throw new Error("The scale does not support inverting!")}toComplex(e){const n=this.getGenome();return n?n.toChromosomal(e):e}fromComplex(e){return ph(e)?this.getGenome().toContinuous(e.chrom,e.pos):e}fromComplexInterval(e){return this.type==="locus"&&fv(e)?this.getGenome().toContinuousInterval(e):e}_getViewPaths(){return this.members.map(e=>e.view.getPathString()).join(", ")}_reduceDomains(e){const n=this.members.map(e).filter(r=>!!r);if(n.length)return n.reduce((r,i)=>r.extendAll(i))}}function Av(t,e){if(e==gv||e==vh){if(yf(t))return e;throw new Error(`${t} does not support ${e} data type. Only positional channels do.`)}const n={x:["band","band","linear"],y:["band","band","linear"],size:[void 0,"point","linear"],opacity:[void 0,"point","linear"],fillOpacity:[void 0,"point","linear"],strokeOpacity:[void 0,"point","linear"],color:["ordinal","ordinal","linear"],fill:["ordinal","ordinal","linear"],stroke:["ordinal","ordinal","linear"],strokeWidth:[void 0,void 0,"linear"],shape:["ordinal","ordinal",void 0],dx:[void 0,void 0,"null"],dy:[void 0,void 0,"null"],angle:[void 0,void 0,"linear"]},i=["uniqueId","facetIndex","semanticScore","search","text","sample"].includes(t)?"null":n[t]?n[t][[wh,bh,yh].indexOf(e)]:e==yh?"linear":"ordinal";if(i===void 0)throw new Error(`Channel "${t}" is not compatible with "${e}" data type. Use of a proper scale may be needed.`);return i}function xv(t,e){kr(e)&&t.type!=="ordinal"&&(t.range=[0,1]),e=="opacity"&&Te(t.type)&&(t.clamp=!0)}function yv(t){return Le(t)}function qa(...t){for(const e of t)if(e!==void 0)return e}class bv{constructor(e){this.channel=e,this.members=[]}get scaleResolution(){var e;return(e=vn(this.members))==null?void 0:e.view.getScaleResolution(this.channel)}pushUnitView(e,n){const r=e.getScaleResolution(this.channel);if(!r)throw new Error("Cannot find a scale resolution!");if(this.scaleResolution&&r!==this.scaleResolution)throw new Error("Shared axes must have a shared scale!");this.members.push({view:e,channel:n})}getAxisProps(){return Ln(this,"axisProps",()=>{const e=this.members.map(n=>{const r=n.view.mark.encoding[n.channel];return"axis"in r&&r.axis});return e.length>0&&e.some(n=>n===null)?null:Eo(e.filter(n=>n!==void 0),"axis",["title"])})}getTitle(){const e=o=>{var a;const s=aa(o.view,o.channel);if(!Ge(s))return{member:o,explicitTitle:qa((a=s.axis)==null?void 0:a.title,s.title),implicitTitle:qa(Pr(s)?s.field:void 0,ua(s)?s.expr:void 0)}},n=this.members.map(e),r=n.filter(o=>{var s;if(Nr(o.member.channel)&&!o.explicitTitle){const a=Cn(o.member.channel);return((s=n.find(u=>u.member.view==o.member.view&&u.member.channel==a))==null?void 0:s.explicitTitle)===void 0}return!0}),i=new Set(r.map(o=>qa(o.explicitTitle,o.implicitTitle)).filter(W));return i.size?[...i].join(", "):null}}class Ch extends ih{constructor(e,n,r,i){super(e,n,r,i),this.spec=e}}class tn extends kn{constructor(e,n,r,i){super(e,n,r,i),this.spec=e,this.children=(e.layer||[]).map((o,s)=>{if(nu(o)||tu(o))return n.createView(o,this,"layer"+s);throw new Error("LayerView accepts only unit or layer specs as children!")})}*[Symbol.iterator](){for(const e of this.children)yield e}render(e,n,r={}){if(this.isVisible()){e.pushView(this,n);for(const i of this.children)i.render(e,n,r);e.popView(this)}}propagateInteractionEvent(e){this.handleInteractionEvent(void 0,e,!0),this.children.length&&this.children.at(-1).propagateInteractionEvent(e),!e.stopped&&this.handleInteractionEvent(void 0,e,!1)}}class Eh{constructor(e,n){this.n=e,this.maxCols=n??1/0}get nRows(){return this.maxCols==1/0?1:Math.ceil(this.n/this.maxCols)}get nCols(){return Math.min(this.n,this.maxCols)}get rowIndices(){const e=[],n=this.nCols,r=this.nRows;for(let i=0;i<r;i++){const o=[];e.push(o);for(let s=0;s<n;s++){const a=i*n+s;a<this.n&&o.push(a)}}return e}get colIndices(){const e=[],n=this.nCols,r=this.nRows;for(let i=0;i<n;i++){const o=[];e.push(o);for(let s=0;s<r;s++){const a=s*n+i;a<this.n&&o.push(a)}}return e}getCellIndex(e,n){let r=0;if(this.maxCols==1/0)r=n==0?e:void 0;else{if(e>=this.maxCols)return;r=n*this.nCols+e}return r<this.n?r:void 0}getCellCoords(e){if(!(e<0||e>=this.n))return[e%this.nCols,Math.floor(e/this.nCols)]}}function ut(t){return()=>t}const ct=class{static create(e,n,r,i){return new ct(ut(e),ut(n),ut(r),ut(i))}_offset(e,n){const r=this["_"+e];if(n===0)return r;switch(typeof n){case"number":return()=>r()+n;case"function":return()=>r()+n();default:throw new Error("Not a number of function")}}_passThrough(e){return this._offset(e,0)}constructor(e,n,r,i){this._x=e,this._y=n,this._width=r,this._height=i}get x(){return this._x()}get y(){return this._y()}get width(){return this._width()}get height(){return this._height()}get x2(){return this._x()+this._width()}get y2(){return this._y()+this._height()}equals(e){return e?this===e||this.x===e.x&&this.y===e.y&&this.width===e.width&&this.height===e.height:!1}modify(e){if(!Object.keys(e).length)return this;const n=r=>{const i=e[r];return typeof i=="number"?ut(i):typeof i=="function"?i:this._passThrough(r)};return new ct(n("x"),n("y"),n("width"),n("height"))}translate(e,n){return e===0&&n===0?this:new ct(this._offset("x",e),this._offset("y",n),this._passThrough("width"),this._passThrough("height"))}translateBy(e){return this.translate(e.x,e.y)}expand(e,n=1){return e.left==0&&e.top==0&&e.right==0&&e.bottom==0?this:new ct(e.left?this._offset("x",-e.left*n):this._passThrough("x"),e.top?this._offset("y",-e.top*n):this._passThrough("y"),e.width?this._offset("width",e.width*n):this._passThrough("width"),e.height?this._offset("height",e.height*n):this._passThrough("height"))}shrink(e){return this.expand(e,-1)}intersect(e){return this===e?this:new ct(()=>Math.max(this.x,e.x),()=>Math.max(this.y,e.y),()=>Math.min(this.x2,e.x2)-Math.max(this.x,e.x),()=>Math.min(this.y2,e.y2)-Math.max(this.y,e.y))}isDefined(){return this.width>=0&&this.height>=0}flatten(){return new ct(ut(this.x),ut(this.y),ut(this.width),ut(this.height))}containsPoint(e,n){return e>=this.x&&e<this.x2&&n>=this.y&&n<this.y2}normalizePoint(e,n){return{x:(e-this.x)/this.width,y:(n-this.y)/this.height}}toString(){return`Rectangle: x: ${this.x}, y: ${this.y}, width: ${this.width}, height: ${this.height}`}};let zn=ct;$h(zn,"ZERO",ct.create(0,0,0,0));function wv(t,e,n){return n=(n-t)/(e-t),n=Math.max(0,Math.min(1,n)),n*n*(3-2*n)}class On extends q{get identifier(){}handle(e){throw new Error("Source does not handle incoming data!")}async load(){}}function Sh(t){const e={...t.format};if(e.type??(e.type=Sv(t)&&vv(t.url)),e.parse??(e.parse="auto"),!e.type)throw new Error("Format for the data source was not defined and it could not be inferred: "+JSON.stringify(t));return e}function vv(t){var e;if(Array.isArray(t)&&(t=t[0]),t)return(e=t.match(/\.(csv|tsv|json)/))==null?void 0:e[1]}const So=t=>typeof t!="object"?Cv:Ev,Cv=t=>({data:t}),Ev=t=>t;function Sv(t){return"url"in t}function Dv(t){return"dynamicCallbackSource"in t}class Dh extends On{constructor(e){super(),this.callback=e}loadSynchronously(){if(!this.callback)return;const e=this.callback();if(!e||typeof e[Symbol.iterator]!="function")throw new Error("Dynamic data callback didn't return iterable data!");this.reset(),this.beginBatch({type:"file"});let n;for(const r of e)n||(n=So(r)),this._propagate(n(r));this.complete()}async load(){this.loadSynchronously()}}const Bh="chromosome_ticks_and_labels",Fh={x:"width",y:"height"};function Ja(t){return t=="x"?"y":"x"}const _a={x:["bottom","top"],y:["left","right"]},Mh=Object.fromEntries(Object.entries(_a).map(([t,e])=>e.map(n=>[n,t])).flat(1));function nn(t){return Mh[t]}class Bv extends tn{constructor(e,n,r,i){const o=n=="locus",s={...o?Iv:Ih,...Mv(n,e),...e};if(super(o?Tv(s):Th(s),r,i,`axis_${e.orient}`),this.axisProps=s,this.axisUpdateRequested=!0,this._addBroadcastHandler("layout",()=>{this.axisUpdateRequested=!0}),this.previousScaleDomain=[],this.axisLength=void 0,this.ticks=[],this.tickSource=new Dh(()=>this.ticks),o){const a=nn(this.axisProps.orient),u=this.getScaleResolution(a).getGenome();this.findChildByName(Bh).getDynamicDataSource=()=>new Dh(()=>u.chromosomes)}this.blockEncodingInheritance=!0}getOrient(){return this.axisProps.orient}getSize(){const e={px:this.getPerpendicularSize()},n={grow:1};return Mh[this.axisProps.orient]=="x"?new en(n,e):new en(e,n)}getPerpendicularSize(){return $a(this.axisProps)}getDynamicDataSource(){return this.tickSource}_updateAxisData(){const e=nn(this.axisProps.orient),n=this.getScaleResolution(e).getScale(),r=n.domain();if(rf(r,this.previousScaleDomain)&&!this.axisUpdateRequested)return;this.previousScaleDomain=r;const i=this.ticks,o=Fv(this.axisProps,n,this.axisLength,i);o!==i&&(this.ticks=o,this.tickSource.loadSynchronously()),this.axisUpdateRequested=!1}onBeforeRender(){super.onBeforeRender(),this._updateAxisData()}render(e,n,r={}){this.isVisible()&&(this.axisLength=n[Fh[nn(this.getOrient())]],super.render(e,n,r))}isPickingSupported(){return!1}}function $a(t){const e=nn(t.orient);let n=t.ticks&&t.tickSize||0;return t.labels&&(n+=t.labelPadding,e=="x"?n+=t.labelFontSize:n+=30),t.title&&(n+=t.titlePadding+t.titleFontSize),n=Math.min(t.maxExtent||1/0,Math.max(t.minExtent||0,n)),n}function Fv(t,e,n,r=[]){const i=a=>25+60*wv(100,700,a);let o=me(t.tickCount)?t.tickCount:Math.round(n/i(n));o=sh(e,o,t.tickMinStep);const s=t.values?ah(e,t.values,o):Gw(e,o);if(wA(s,r,a=>a,a=>a.value))return r;{const a=Hw(e,o,t.format);return s.map(u=>({value:u,label:a(u)}))}}const Ih={values:null,minExtent:20,maxExtent:1/0,offset:0,domain:!0,domainWidth:1,domainColor:"gray",domainDash:null,domainDashOffset:0,domainCap:"square",ticks:!0,tickSize:5,tickWidth:1,tickColor:"gray",tickDash:null,tickDashOffset:0,tickCap:"square",tickCount:null,tickMinStep:null,labels:!0,labelAlign:"center",labelBaseline:"middle",labelPadding:4,labelFontSize:10,labelLimit:180,labelColor:"black",format:null,titleColor:"black",titleFont:"sans-serif",titleFontSize:10,titlePadding:3};function Mv(t,e){const n=e.orient,r=t=="nominal"||t=="ordinal";let i="center",o="middle",s=e.labelAngle??((n=="top"||n=="bottom")&&r?-90:0);switch(n){case"left":i="right";break;case"right":i="left";break;case"top":case"bottom":Math.abs(s)>30?(i=s>0==(n=="bottom")?"left":"right",o="middle"):o=n=="top"?"alphabetic":"top";break}return{labelAlign:i,labelAngle:s,labelBaseline:o}}function Th(t){const e={...t,extent:$a(t)},n=nn(e.orient),r=Ja(n),i=e.orient=="bottom"||e.orient=="right"?1:-1,o=e.orient=="bottom"||e.orient=="left"?1:0,s=()=>({name:"domain",data:{values:[0]},mark:{type:"rule",clip:!1,strokeDash:e.domainDash,strokeCap:e.domainCap,color:e.domainColor,[r]:o,size:e.domainWidth}}),a=()=>({name:"labels",mark:{type:"text",clip:!1,align:e.labelAlign,angle:e.labelAngle,baseline:e.labelBaseline,[r+"Offset"]:(e.tickSize+e.labelPadding)*i,[r]:o,size:e.labelFontSize,color:e.labelColor,minBufferSize:1500},encoding:{[n]:{field:"value",type:"quantitative"},text:{field:"label"}}}),u=()=>({name:"ticks",mark:{type:"rule",clip:!1,strokeDash:e.tickDash,strokeCap:e.tickCap,color:e.tickColor,size:e.tickWidth,minBufferSize:300},encoding:{[r]:{value:o},[r+"2"]:{value:o-e.tickSize/e.extent*(o?1:-1)}}}),c=()=>({name:"title",data:{values:[0]},mark:{type:"text",clip:!1,align:"center",baseline:e.orient=="bottom"?"bottom":"top",angle:[0,90,0,-90][["top","right","bottom","left"].indexOf(e.orient)],text:e.title,color:e.titleColor,[n]:.5,[r]:1-o}}),f=()=>{const h={name:"ticks_and_labels",encoding:{[n]:{field:"value",type:"quantitative"}},layer:[]};return e.ticks&&h.layer.push(u()),e.labels&&h.layer.push(a()),h},l={[Fh[Ja(nn(e.orient))]]:e.extent,data:{dynamicCallbackSource:!0},layer:[]};return e.domain&&l.layer.push(s()),(e.ticks||e.labels)&&l.layer.push(f()),e.title&&l.layer.push(c()),l}const Iv={...Ih,chromTicks:!0,chromTickSize:18,chromTickWidth:1,chromTickColor:"#989898",chromTickDash:[4,2],chromTickDashOffset:1,chromLabels:!0,chromLabelFontSize:13,chromLabelFontWeight:"normal",chromLabelFontStyle:"normal",chromLabelColor:"black",chromLabelAlign:"left",chromLabelPadding:7};function Tv(t){const e={...t,extent:$a(t)},n=nn(e.orient),r=Ja(n),i=e.orient=="bottom"||e.orient=="left"?1:0,o=()=>({name:"chromosome_ticks",mark:{type:"rule",strokeDash:t.chromTickDash,strokeDashOffset:t.chromTickDashOffset,[r]:i,[r+"2"]:i-e.chromTickSize/e.extent*(i?1:-1),color:t.chromTickColor,size:e.chromTickWidth}}),s=()=>{let c;switch(e.orient){case"top":c={y:0,angle:0,paddingX:4,dy:-e.chromLabelPadding,viewportEdgeFadeWidthLeft:20,viewportEdgeFadeWidthRight:20,viewportEdgeFadeDistanceRight:-10,viewportEdgeFadeDistanceLeft:-20};break;case"bottom":c={y:1,angle:0,paddingX:4,dy:e.chromLabelPadding+e.chromLabelFontSize*.73,viewportEdgeFadeWidthLeft:20,viewportEdgeFadeWidthRight:20,viewportEdgeFadeDistanceRight:-10,viewportEdgeFadeDistanceLeft:-20};break;case"left":c={x:1,angle:-90,paddingY:4,dy:-e.chromLabelPadding,viewportEdgeFadeWidthBottom:20,viewportEdgeFadeWidthTop:20,viewportEdgeFadeDistanceBottom:-20,viewportEdgeFadeDistanceTop:-10};break;case"right":c={x:0,angle:90,align:"right",paddingY:4,dy:-e.chromLabelPadding};break;default:c={}}return{name:"chromosome_labels",mark:{type:"text",size:e.chromLabelFontSize,font:e.chromLabelFont,fontWeight:e.chromLabelFontWeight,fontStyle:e.chromLabelFontStyle,color:e.chromLabelColor,align:t.chromLabelAlign,baseline:"alphabetic",clip:!1,...c},encoding:{[n+"2"]:{field:"continuousEnd",type:"locus"},text:{field:"name"}}}};let a;switch(e.orient){case"bottom":case"top":a={};break;case"left":a={labelAngle:-90,labelAlign:"center",labelPadding:6};break;case"right":a={labelAngle:90,labelAlign:"center",labelPadding:6};break;default:a={}}const u=Th({...t,...a});if(t.chromTicks||t.chromLabels){const c={name:Bh,data:{dynamicCallbackSource:!0},encoding:{[n]:{field:"continuousStart",type:"locus",band:0}},layer:[]};if(t.chromTicks&&c.layer.push(o()),t.chromLabels){c.layer.push(s());let f;u.layer.filter(l=>l.name=="ticks_and_labels").forEach(l=>l.layer.filter(h=>h.name=="labels").forEach(h=>{f=h.mark})),f&&(e.orient=="top"||e.orient=="bottom"?(f.viewportEdgeFadeWidthLeft=30,f.viewportEdgeFadeDistanceLeft=40):(f.viewportEdgeFadeWidthBottom=30,f.viewportEdgeFadeDistanceBottom=40))}u.layer.push(c)}return u}const Ph={anchor:"middle",frame:"group",offset:10,orient:"top",align:void 0,angle:0,baseline:"alphabetic",dx:0,dy:0,color:void 0,font:void 0,fontSize:12,fontStyle:"normal",fontWeight:"normal"},Pv={orient:"left",anchor:"middle",align:"right",baseline:"middle",angle:0,fontSize:12},Rv={orient:"top",anchor:"start",align:"left",baseline:"top",offset:-10,dx:10,fontSize:12},Lv={start:0,middle:.5,end:1},kv={start:"left",middle:"center",end:"right"};function Nv(t){if(!t)return;const e=W(t)?{text:t}:t;if(!e.text||e.orient=="none")return;const n={"track-title":Pv,overlay:Rv}[e.style]??{},r={...Ph,...n,...e};let i={},o={x:0,y:0};const s=Lv[r.anchor??"middle"];switch(r.orient){case"top":o={x:s,y:1},i={baseline:"alphabetic",angle:0};break;case"right":o={x:1,y:1-s},i={baseline:"alphabetic",angle:90};break;case"bottom":o={x:s,y:0},i={baseline:"top",angle:0};break;case"left":o={x:0,y:s},i={baseline:"alphabetic",angle:-90};break}const a={...Ph,...i,...n,...e},u={xOffset:0,yOffset:0};switch(r.orient){case"top":u.yOffset=-a.offset;break;case"right":u.xOffset=a.offset;break;case"bottom":u.yOffset=a.offset;break;case"left":u.xOffset=-a.offset;break}return{configurableVisibility:!1,data:{values:[{}]},mark:{type:"text",tooltip:null,clip:!1,...o,...u,text:a.text,align:a.align??kv[a.anchor],angle:a.angle,baseline:a.baseline,dx:a.dx,dy:a.dy,color:a.color,font:a.font,size:a.fontSize,fontStyle:a.fontStyle,fontWeight:a.fontWeight}}}function zv(t,e,n,r){if(t.type=="wheel"){t.uiEvent.preventDefault();const i=t.uiEvent,o=i.deltaMode?120:1;let{x:s,y:a}=t.point;if(r){const u=r.mark.encoders;u.x&&!u.x2&&(s=+u.x(r.datum)*e.width+e.x),u.y&&!u.y2&&(a=(1-+u.y(r.datum))*e.height+e.y)}Math.abs(i.deltaX)<Math.abs(i.deltaY)?n({x:s,y:a,xDelta:0,yDelta:0,zDelta:i.deltaY*o/300}):n({x:s,y:a,xDelta:-i.deltaX*o,yDelta:0,zDelta:0})}else if(t.type=="mousedown"&&t.uiEvent.button===0){const i=t.uiEvent;i.preventDefault();let o=i;const s=u=>{n({x:o.clientX,y:o.clientY,xDelta:u.clientX-o.clientX,yDelta:u.clientY-o.clientY,zDelta:0}),o=u},a=u=>{document.removeEventListener("mousemove",s),document.removeEventListener("mouseup",a)};document.addEventListener("mouseup",a,!1),document.addEventListener("mousemove",s,!1)}}class Rh extends kn{constructor(n,r,i,o,s){super(n,r,i,o);he(this,Jr);he(this,$e);he(this,Bo);he(this,Fo);he(this,rn);he(this,_r);he(this,$r);he(this,ei);he(this,Mo);he(this,Gn,1/0);he(this,Un,10);he(this,Re,[]);he(this,Hn,0);this.spec=n,Yn(this,Un,n.spacing??10),Yn(this,Gn,s),Yn(this,Re,[]),this.wrappingFacet=!1,this._createChildren()}_createChildren(){}appendChild(n){n.parent??(n.parent=this),Q(this,Re).push(ue(this,Jr,fu).call(this,n)),ed(this,Hn)._++}setChildren(n){for(const r of n)this.appendChild(r)}replaceChild(n,r){const i=Q(this,Re).findIndex(o=>o.view==n);if(i>=0)Q(this,Re)[i]=ue(this,Jr,fu).call(this,r);else throw new Error("Not my child view!")}get children(){return Q(this,Re).map(n=>n.view)}get childCount(){return Q(this,Re).length}onScalesResolved(){super.onScalesResolved(),ue(this,Fo,rd).call(this)}*[Symbol.iterator](){for(const n of Q(this,Re)){n.background&&(yield n.background);for(const r of Object.values(n.axes))r&&(yield r);yield n.view,n.title&&(yield n.title)}}getOverhang(){const n=ue(this,rn,ni).call(this,"column"),r=ue(this,rn,ni).call(this,"row");return!n.length||!r.length?Qe.zero():new Qe(r.at(0).axisBefore,n.at(-1).axisAfter,r.at(-1).axisAfter,n.at(0).axisBefore)}getSize(){return this._cache("size",()=>new en(ue(this,$r,du).call(this,"column"),ue(this,$r,du).call(this,"row")).subtractPadding(this.getOverhang()).addPadding(this.getPadding()))}render(n,r,i={}){if(!this.isVisible())return;r=r.shrink(this.getPadding()),n.pushView(this,r);const o={devicePixelRatio:this.context.glHelper.dpr},s=eh(ue(this,_r,hu).call(this,"column"),r.width,o),a=eh(ue(this,_r,hu).call(this,"row"),r.height,o),u=new Eh(Q(this,$e,Ft).length,Q(this,Gn)??1/0);for(const[c,f]of Q(this,$e,Ft).entries()){const{view:l,axes:h,background:p,title:d}=f,[g,m]=u.getCellCoords(c),A=s[ue(this,ei,pu).call(this,"column",g)],y=a[ue(this,ei,pu).call(this,"row",m)],b=l.getSize(),C=l.getPadding().subtract(l.getOverhang()),B=A.location+C.left,E=y.location+C.top,w=(b.width.grow?A.size:b.width.px)-C.width,X=(b.height.grow?y.size:b.height.px)-C.height,H=new zn(()=>r.x+B,()=>r.y+E,()=>w,()=>X);f.coords=H,p==null||p.render(n,H,i);const ae=Uv(l);ae&&l.render(n,H,i);for(const[M,Se]of Object.entries(h)){const _=Se.axisProps;let ve;const je=Se.getPerpendicularSize();M=="bottom"?ve=H.translate(0,H.height+_.offset).modify({height:je}):M=="top"?ve=H.translate(0,-je-_.offset).modify({height:je}):M=="left"?ve=H.translate(-je-_.offset,0).modify({width:je}):M=="right"&&(ve=H.translate(H.width+_.offset,0).modify({width:je})),Se.render(n,ve)}ae||l.render(n,H,i),d==null||d.render(n,H,{...i,clipRect:void 0})}n.popView(this)}propagateInteractionEvent(n){if(this.handleInteractionEvent(void 0,n,!0),n.stopped)return;const r=Q(this,$e,Ft).find(o=>o.coords.containsPoint(n.point.x,n.point.y)),i=r==null?void 0:r.view;i&&(i.propagateInteractionEvent(n),(i instanceof we||i instanceof tn)&&zv(n,r.coords,o=>ue(this,Mo,id).call(this,r.coords,r.view,o),this.context.getCurrentHover())),!n.stopped&&this.handleInteractionEvent(void 0,n,!1)}getDefaultResolution(n,r){return"independent"}}Gn=new WeakMap,Un=new WeakMap,Re=new WeakMap,Hn=new WeakMap,Jr=new WeakSet,fu=function(n){var i;const r={view:n,background:void 0,axes:{},coords:zn.ZERO};if(n instanceof we||n instanceof tn){const o=(i=n.spec)==null?void 0:i.view;if(o!=null&&o.fill||o!=null&&o.stroke){const a=new we(Ov(o),this.context,n,"background"+Q(this,Hn));a.blockEncodingInheritance=!0,r.background=a}const s=Nv(n.spec.title);if(s){const a=new we(s,this.context,n,"title"+Q(this,Hn));a.blockEncodingInheritance=!0,r.title=a}}return r},$e=new WeakSet,Ft=function(){return Q(this,Re).filter(n=>n.view.isVisible())},Bo=new WeakSet,nd=function(){return new Eh(Q(this,$e,Ft).length,Q(this,Gn)??1/0)},Fo=new WeakSet,rd=function(){if(Object.keys(this.resolutions.axis).length)throw new Error("ConcatView does not (currently) support shared axes!");for(const n of Q(this,Re)){const{view:r,axes:i}=n,o=(s,a,u)=>{const c=s.getAxisProps();if(c!==null){if(!c.orient){for(const f of _a[a])if(!i[f]){c.orient=f;break}if(!c.orient)throw new Error("No slots available for an axis! Perhaps a LayerView has more than two children?")}if(c.title??(c.title=s.getTitle()),!_a[a].includes(c.orient))throw new Error(`Invalid axis orientation "${c.orient}" on channel "${a}"!`);if(i[c.orient])throw new Error(`An axis with the orient "${c.orient}" already exists!`);i[c.orient]=new Bv(c,s.scaleResolution.type,this.context,u)}};if(r instanceof we||r instanceof tn)for(const s of["x","y"]){const a=r.resolutions.axis[s];a&&o(a,s,r)}if(r instanceof tn){for(const s of r.children)for(const[a,u]of Object.entries(s.resolutions.axis)){const c=u.getAxisProps();c&&c.orient&&o(u,a,s)}for(const s of r.children)for(const[a,u]of Object.entries(s.resolutions.axis)){const c=u.getAxisProps();c&&!c.orient&&o(u,a,s)}}}},rn=new WeakSet,ni=function(n){const r=n=="column"?["left","right"]:["top","bottom"],i=n=="column"?"width":"height",o=(s,a)=>s.map(u=>{const c=Q(this,$e,Ft)[u].axes[r[a]];if(c)return Math.max(c.getPerpendicularSize()+c.axisProps.offset,0);const f=Q(this,$e,Ft)[u].view.getOverhang();return n=="column"?a?f.right:f.left:a?f.bottom:f.top}).reduce((u,c)=>Math.max(u,c),0);return Q(this,Bo,nd)[n=="column"?"colIndices":"rowIndices"].map(s=>({axisBefore:o(s,0),axisAfter:o(s,1),view:Pw(s.map(a=>Q(this,$e,Ft)[a].view.getSize()[i]))}))},_r=new WeakSet,hu=function(n){const r=ue(this,rn,ni).call(this,n),i=[];i.push(Xr);for(const[o,s]of r.entries())o>0&&i.push({px:Q(this,Un),grow:0}),(o==0||this.wrappingFacet)&&i.push(Xr),i.push({px:s.axisBefore,grow:0}),i.push(s.view),i.push({px:s.axisAfter,grow:0}),(o==r.length-1||this.wrappingFacet)&&i.push(Xr);return i},$r=new WeakSet,du=function(n){let r=0,i=0;const o=(n=="row"&&this.spec.height)??(n=="column"&&this.spec.width);if(o||o===0)return th(o);const s=ue(this,rn,ni).call(this,n);for(const[a,u]of s.entries())a>0&&(i+=Q(this,Un)),(a==0||this.wrappingFacet)&&(i+=0),i+=u.axisBefore,i+=u.view.px??0,r+=u.view.grow??0,i+=u.axisAfter,(a==s.length-1||this.wrappingFacet)&&(i+=0);return{px:i,grow:r}},ei=new WeakSet,pu=function(n,r){return n=="row"&&this.wrappingFacet?1+6*r+2:2+4*r+1},Mo=new WeakSet,id=function(n,r,i){for(const[o,s]of Object.entries(Gv(r))){if(s.size<=0)continue;const a=n.normalizePoint(i.x,i.y),u=n.normalizePoint(i.x+i.xDelta,i.y+i.yDelta),c={x:u.x-a.x,y:u.y-a.y};for(const f of s)f.zoom(2**i.zDelta,o=="y"?1-a[o]:a[o],o=="x"?c.x:-c.y)}this.context.animator.requestRender()};function Ov(t){return{configurableVisibility:!1,data:{values:[{}]},mark:{fill:null,strokeWidth:1,fillOpacity:t.fill?1:0,...t,type:"rect",clip:!1,tooltip:null}}}function Gv(t){const e={x:new Set,y:new Set};return t.visit(n=>{for(const[r,i]of Object.entries(e)){const o=n.getScaleResolution(r);o&&o.isZoomable()&&i.add(o)}}),e}function Uv(t){let e=!0;return t.visit(n=>{n instanceof we&&e&&(e=n.mark.properties.clip)}),e}class eu extends Rh{constructor(e,n,r,i){super(e,n,r,i,iu(e)?e.columns:ru(e)?1:1/0),this.spec=e}_createChildren(){const e=this.spec,n=iu(e)?e.concat:ru(e)?e.vconcat:e.hconcat;this.setChildren(n.map((r,i)=>this.context.createView(r,this,"grid"+i)))}}class Hv{constructor(){this.types=[];const e=n=>(r,i,o,s)=>new n(r,i,o,r.name??s);this.addViewType(Qv,e(Ch)),this.addViewType(nu,e(tn)),this.addViewType(tu,e(we)),this.addViewType(ru,e(eu)),this.addViewType(jv,e(eu)),this.addViewType(iu,e(eu))}addViewType(e,n){this.types.push({specGuard:e,factory:n})}createView(e,n,r,i){const o=this.types.find(s=>s.specGuard(e));if(o)return o.factory(e,n,r,i??"unnamed");throw new Error("Invalid spec, cannot figure out the view type from the properties: "+JSON.stringify([...Object.keys(e)]))}isViewSpec(e){const n=this.types.filter(r=>r.specGuard(e));if(n.length>1)throw new Error("Ambiguous spec. Cannot create a view!");return n.length==1}}function tu(t){return"mark"in t&&(W(t.mark)||Le(t.mark))}function nu(t){return"layer"in t&&Le(t.layer)}function Lh(t){return t&&(tu(t)||nu(t))&&"aggregateSamples"in t}function Qv(t){return"import"in t}function ru(t){return"vconcat"in t&&Fe(t.vconcat)}function jv(t){return"hconcat"in t&&Fe(t.hconcat)}function iu(t){return"concat"in t&&Fe(t.concat)}const Vv={point:xw,rect:fw,rule:ww,link:Sw,text:Tw};class we extends kn{constructor(e,n,r,i){super(e,n,r,i),this.spec=e;const o=Vv[this.getMarkType()];if(o)this.mark=new o(this);else throw new Error(`No such mark: ${this.getMarkType()}`);this.sampleAggregateViews=[],this._initializeAggregateViews(),this.coords=void 0}*[Symbol.iterator](){for(const e of this.sampleAggregateViews)yield e}replaceChild(e,n){const r=this.sampleAggregateViews.indexOf(e);if(r>=0)this.sampleAggregateViews[r]=n;else throw new Error("Not my child view!")}render(e,n,r={}){this.isVisible()&&(this.coords=n,e.pushView(this,n),e.renderMark(this.mark,r),e.popView(this))}getMarkType(){return typeof this.spec.mark=="object"?this.spec.mark.type:this.spec.mark}resolve(e){const n=this.mark.encoding;for(const[r,i]of Object.entries(n)){if(!Pe(i))continue;let o=Cn(i.resolutionChannel??r);if(e=="axis"&&!kr(o))continue;let s=this;for(;s.parent instanceof kn&&["shared","excluded"].includes(s.parent.getConfiguredOrDefaultResolution(o,e))&&s.getConfiguredOrDefaultResolution(o,e)!="excluded";)s=s.parent;s.resolutions[e][o]||(s.resolutions[e][o]=e=="scale"?new mv(o):new bv(o)),kr(r)?s.resolutions[e][o].pushUnitView(this,r):e=="scale"&&s.resolutions[e][o].pushUnitView(this,r)}}getAccessor(e){return this._cache("accessor/"+e,()=>{const n=this.mark.encoding;if(n&&n[e])return this.context.accessorFactory.createAccessor(n[e])})}getFacetAccessor(e){const n=this.getAccessor("sample");return n||super.getFacetAccessor(this)}getCollector(){return this.context.dataFlow.findCollectorByKey(this)}_validateDomainQuery(e){if(Nr(e))throw new Error(`getDomain(${e}), must only be called for primary channels!`);const n=this.mark.encoding[e];if(!Pe(n))throw new Error("The channel has no scale, cannot get domain!");return n}getConfiguredDomain(e){const n=this._validateDomainQuery(e),r=n&&n.scale&&n.scale.domain;if(r){const i=this.getScaleResolution(n.resolutionChannel??e);return xh(n.type??"nominal",i.fromComplexInterval(r))}}extractDataDomain(e){const r=this._validateDomainQuery(e).type??"nominal",i=a=>{let u;const c=this.mark.encoding[a];if(c){const f=this.context.accessorFactory.createAccessor(c);if(f)if(u=xh(r),f.constant)u.extend(f({}));else{const l=this.getCollector();l!=null&&l.completed&&l.visitData(h=>u.extend(f(h)))}}return u};let o=i(e);const s=ca[e];if(s){const a=i(s);a&&o.extendAll(a)}return o}getZoomLevel(){const e=n=>{var r;return((r=this.getScaleResolution(n))==null?void 0:r.getZoomLevel())??1};return Lr.map(e).reduce((n,r)=>n*r,1)}_initializeAggregateViews(){if(Lh(this.spec))for(const e of this.spec.aggregateSamples){const n=e.transform??[];n.length&&vn(n).type!="collect"&&n.push({type:"collect"}),n.push({type:"mergeFacets"}),e.transform=n,e.encoding={...e.encoding??{},sample:null};const r=this.context.createView(e,this,"summaryView");r.getFacetFields=i=>{},this.sampleAggregateViews.push(r)}}propagateInteractionEvent(e){e.target=this}getDefaultResolution(e,n){return e=="x"?"shared":"independent"}}function*ou(t,e=[]){for(const[n,r]of t.entries())if(r instanceof Map)for(const i of ou(r,[...e,n]))yield i;else yield[[...e,n],r]}class su extends q{constructor(e){super(),this.params=e??{type:"collect"},this.observers=[],this.facetBatches=void 0,this._init()}_init(){this._data=[],this.facetBatches=new Tt([],JSON.stringify),this.facetBatches.set(void 0,this._data)}reset(){super.reset(),this._init()}handle(e){this._data.push(e)}beginBatch(e){gw(e)&&(this._data=[],this.facetBatches.set(Ke(e.facetId),this._data))}complete(){var i,o;const e=(i=this.params)==null?void 0:i.sort,n=e?yu(e.field,e.order):void 0,r=s=>{n&&s.sort(n)};if((o=this.params.groupby)!=null&&o.length){if(this.facetBatches.size>1)throw new Error("TODO: Support faceted data!");const s=this.params.groupby.map(u=>O(u)),a=hi(this._data,...s);this.facetBatches.clear();for(const[u,c]of ou(a))this.facetBatches.set(u,c)}for(const s of this.facetBatches.values())r(s);if(this.children.length)for(const[s,a]of this.facetBatches.entries()){if(s){const u={type:"facet",facetId:s};for(const c of this.children)c.beginBatch(u)}for(const u of a)this._propagate(u)}super.complete();for(const s of this.observers)s(this)}getData(){switch(this._checkStatus(),this.facetBatches.size){case 0:return[];case 1:return[...this.facetBatches.values()][0];default:{const e=this.facetBatches;return{[Symbol.iterator]:function*(){for(const r of e.values())for(let i=0;i<r.length;i++)yield r[i]}}}}}visitData(e){this._checkStatus();for(const n of this.facetBatches.values())for(let r=0;r<n.length;r++)e(n[r])}getItemCount(){let e=0;for(const n of this.facetBatches.values())e+=n.length;return e}_checkStatus(){if(!this.completed)throw new Error("Data propagation is not completed! No data are available.")}}class Do{constructor(){this.ids=[],this.values=[],this.length=0}clear(){this.length=0}push(e,n){let r=this.length++;for(;r>0;){const i=r-1>>1,o=this.values[i];if(n>=o)break;this.ids[r]=this.ids[i],this.values[r]=o,r=i}this.ids[r]=e,this.values[r]=n}pop(){if(this.length===0)return;const e=this.ids[0];if(this.length--,this.length>0){const n=this.ids[0]=this.ids[this.length],r=this.values[0]=this.values[this.length],i=this.length>>1;let o=0;for(;o<i;){let s=(o<<1)+1;const a=s+1;let u=this.ids[s],c=this.values[s];const f=this.values[a];if(a<this.length&&f<c&&(s=a,u=this.ids[a],c=f),c>=r)break;this.ids[o]=u,this.values[o]=c,o=s}this.ids[o]=n,this.values[o]=r}return e}peek(){if(this.length!==0)return this.ids[0]}peekValue(){if(this.length!==0)return this.values[0]}shrink(){this.ids.length=this.values.length=this.length}}class Yv extends q{get behavior(){return at}constructor(e){super(),this.params=e,this.startAccessor=O(e.start),this.endAccessor=O(e.end),this.chromAccessor=e.chrom?O(e.chrom):n=>{},this.weightAccessor=e.weight?O(e.weight):n=>1,this.as={coverage:e.as||"coverage",start:e.asStart||e.start,end:e.asEnd||e.end,chrom:e.asChrom||e.chrom},this.createSegment=new Function("start","end","coverage","chrom","return {"+Object.entries(this.as).filter(([n,r])=>r).map(([n,r])=>`${JSON.stringify(r)}: ${n}`).join(", ")+"};"),this.ends=new Do}reset(){super.reset(),this.initialize()}initialize(){const e=this.as.coverage,n=this.as.end,r=this.as.chrom,i=this.startAccessor,o=this.endAccessor,s=this.chromAccessor,a=this.weightAccessor;let u,c,f,l=0,h;const p=this.ends;p.clear();const d=(m,A,y)=>{if(m==A)return;let b=!1;u&&(u[e]===y?(u[n]=A,b=!0):u[e]!=0&&this._propagate(u)),b||(u=this.createSegment(m,A,y,f))},g=()=>{let m;for(;(m=p.peekValue())!==void 0;)d(h,m,l),h=m,l-=p.pop();h=void 0,u&&(this._propagate(u),u=void 0)};this.handle=m=>{const A=i(m);let y;for(;(y=p.peekValue())!==void 0&&y<A;)d(h,y,l),h=y,l-=p.pop();if(r){let C=s(m);C!==c&&(g(),f=C,c=f)}h!==void 0&&d(h,A,l),h=A;const b=a(m);l+=b,p.push(b,o(m))},this.complete=()=>{g(),super.complete()}}}function Wv(t,e,n=0,r=t.length){const i=new Do,o=r-n;let s;for(s=0;s<e&&s<o;s++)i.push(s,t[n+s]);for(;s<o;s++){const c=t[n+s];c>=i.peekValue()&&(i.push(s,c),i.pop())}const a=[];let u;for(;(u=i.pop())!==void 0;)a.push(n+u);return a.reverse()}class Xv{constructor(e,n=-1/0,r=1/0){this.maxSize=e,this.lowerLimit=n,this.upperLimit=r;const i=this.maxSize*2+1;this.lowerLimits=new Float64Array(i),this.upperLimits=new Float64Array(i),this.lowerChildren=new Int32Array(i),this.upperChildren=new Int32Array(i),this.reset()}reset(){this.lowerLimits.fill(0),this.upperLimits.fill(0),this.lowerChildren.fill(0),this.upperChildren.fill(0),this.n=1,this.lowerLimits[0]=this.lowerLimit,this.upperLimits[0]=this.upperLimit}_findSlot(e,n,r=0){if(e>=this.lowerLimits[r]&&n<=this.upperLimits[r]){const i=this.lowerChildren[r];if(i){const o=this._findSlot(e,n,i);return o>=0?o:this._findSlot(e,n,this.upperChildren[r])}else return r}else return-1}reserve(e,n){if(n-e<=0)throw new Error("Cannot reserve an empty or negative-size slot!");if(this.n+1>this.lowerLimits.length)return!1;const r=this._findSlot(e,n);if(r<0)return!1;const i=this.n++,o=this.n++;return this.lowerLimits[i]=this.lowerLimits[r],this.upperLimits[i]=e,this.lowerLimits[o]=n,this.upperLimits[o]=this.upperLimits[r],this.lowerChildren[r]=i,this.upperChildren[r]=o,!0}}class Zv extends q{constructor(e,n){if(super(),this.params=e,this._data=[],this.channel=e.channel??"x",!["x","y"].includes(this.channel))throw new Error("Invalid channel: "+this.channel);this.posAccessor=O(this.params.pos),this.posBisector=fi(this.posAccessor),this.scoreAccessor=O(this.params.score),this.widthAccessor=O(this.params.width),this.laneAccessor=this.params.lane?O(this.params.lane):i=>0,this.padding=this.params.padding??0,this.reservationMaps=new Map,this.resolution=n.getScaleResolution(this.channel);const r=()=>this._filterAndPropagate();this.schedule=()=>n.context.animator.requestTransition(r),this.resolution.addEventListener("domain",i=>this.schedule()),n._addBroadcastHandler("layoutComputed",()=>this.schedule())}complete(){const e=this.posAccessor;this._data.sort((n,r)=>e(n)-e(r)),this._scores=this._data.map(this.scoreAccessor);for(const n of new Set(this._data.map(this.laneAccessor)))this.reservationMaps.set(n,new Xv(200));this.schedule(),super.complete()}_filterAndPropagate(){var s;super.reset();const e=this.resolution.getScale(),n=(s=this.resolution.members[0].view.coords)==null?void 0:s[this.channel=="x"?"width":"height"];if(!n)return;for(const a of this.reservationMaps.values())a.reset();const r=e.domain(),i=70,o=Wv(this._scores,i,this.posBisector.left(this._data,r[0]),this.posBisector.right(this._data,r[1]));for(const a of o){const u=this._data[a],c=e(this.posAccessor(u))*n,f=this.widthAccessor(u)/2+this.padding;this.reservationMaps.get(this.laneAccessor(u)).reserve(c-f,c+f)&&this._propagate(u)}super.complete()}reset(){super.reset(),this._data=[],this.groups=new Map}handle(e){this._data.push(e)}}class Kv extends q{constructor(e){super(),this.params=e,this.predicate=void 0}initialize(){this.predicate=sa(this.params.expr,this.getGlobalObject())}handle(e){this.predicate(e)&&this._propagate(e)}}const qv="0".charCodeAt(0);function*Jv(t,e=","){const n=e.charCodeAt(0);let r=0;for(let i=0;i<t.length;i++){const o=t.charCodeAt(i);o==n?(yield r,r=0):r=r*10+o-qv}yield r}class _v extends q{get behavior(){return at}constructor(e){super();const n=O(e.exons??"exons"),r=O(e.start??"start"),[i,o]=e.as||["exonStart","exonEnd"];this.handle=s=>{let a=r(s),u=a,c=!0;const f=n(s);for(const l of Jv(f)){if(c)u=a+l;else{a=u+l;const h=Object.assign({},s);h[i]=u,h[o]=a,this._propagate(h)}c=!c}}}}class $v extends q{get behavior(){return at}constructor(e){super();const n=Ke(e.field).map(o=>O(o)),r=Ke(e.separator),i=Ke(e.as||e.field);if(n.length!==r.length||n.length!==i.length)throw new Error(`Lengths of "separator" (${r.length}), "fields" (${n.length}), and "as" (${i.length}) do not match!`);this.handle=o=>{if(n.some(u=>!u(o)))return;const s=n.map((u,c)=>u(o).split(r[c]));eC(s,o);const a=s[0].length;for(let u=0;u<a;u++){const c=Object.assign({},o);for(let f=0;f<n.length;f++)c[i[f]]=s[f][u];this._propagate(c)}}}}function eC(t,e){const n=t.map(r=>r.length);if(!n.every(r=>r==n[0]))throw new Error("Mismatching number of elements in the fields to be split: "+JSON.stringify(e))}class tC extends q{get behavior(){return Bt}constructor(e){super(),this.params=e,this.as=e.as,this.fn=void 0}initialize(){this.fn=sa(this.params.expr,this.getGlobalObject())}handle(e){e[this.as]=this.fn(e),this._propagate(e)}}class kh extends q{get behavior(){return Bt}constructor(e,n){super();const r=e.channel??"x";if(!["x","y"].includes(r))throw new Error("Invalid channel: "+r);const i=n.getScaleResolution(r).getGenome();if(!i)throw new Error("LinearizeGenomicCoordinate transform requires a locus scale!");const o=O(e.chrom),s=Ke(e.pos).map(d=>O(d)),a=Ke(e.as);if(s.length!=a.length)throw new Error('The number of "pos" and "as" elements must be equal!');const u=Ke(e.offset);let c;if(u.length==0)c=new Array(s.length).fill(0);else if(u.length==1)c=new Array(s.length).fill(u[0]);else if(u.length==s.length)c=u;else throw new Error(`Invalid "offset" parameter: ${JSON.stringify(e.offset)}!`);const f=new Function("datum","chromOffset","posAccessors",a.map((d,g)=>`datum[${JSON.stringify(d)}] = chromOffset + +posAccessors[${g}](datum) - ${c[g]};`).join(`
+ */const Ww="locus",Xw="index";var Zw=5;function Kw(t){const e=t.type;return!t.bins&&(e===yn||e===br||e===wr)}function uh(t){return Te(t)&&![Ze,Xw,Ww].includes(t)}function ch(t){return t||{warn:(e,...n)=>console.warn(e,...n)}}var qw=li(["set","modified","clear","type","scheme","schemeExtent","schemeCount","domain","domainMin","domainMid","domainMax","domainRaw","domainImplicit","nice","zero","bins","range","rangeStep","round","reverse","interpolate","interpolateGamma","zoom","fp64","name"]);function lh(t,e,n){n=ch(n);for(const r in t)if(!qw[r]){if(r==="padding"&&uh(e.type))continue;ge(e[r])?e[r](t[r]):n.warn("Unsupported scale property: "+r)}iv(e,t,rv(e,t,ev(e,t,n)))}function Jw(t,e){const n=_w(t),r=N(n);if(!r)throw new Error("Unknown scale type: "+n);const i=r();return lh(t,i,e),i}function _w(t){var e=t.type,n="",r;return e===Ze?Ze+"-"+yn:($w(t)&&(r=t.rawDomain?t.rawDomain.length:t.domain?t.domain.length+ +(t.domainMid!=null):0,n=r===2?Ze+"-":r===3?bn+"-":""),(n+e||yn).toLowerCase())}function $w(t){const e=t.type;return Te(e)&&e!==Vl&&e!==Yl&&(t.scheme||t.range&&t.range.length&&t.range.every(W))}function ev(t,e,n){if(!t.domain)return 0;n=ch(n);var r=tv(t,e.domainRaw,n);if(r>-1)return r;var i=e.domain,o=t.type,s=e.zero||e.zero===void 0&&Kw(t),a,u;return i?(uh(o)&&e.padding&&i[0]!==ke(i)&&(i=nv(o,i,e.range,e.padding,e.exponent,e.constant)),(s||e.domainMin!=null||e.domainMax!=null||e.domainMid!=null)&&(a=(i=i.slice()).length-1||1,s&&(i[0]>0&&(i[0]=0),i[a]<0&&(i[a]=0)),e.domainMin!=null&&(i[0]=e.domainMin),e.domainMax!=null&&(i[a]=e.domainMax),e.domainMid!=null&&(u=e.domainMid,(u<i[0]||u>i[a])&&n.warn("Scale domainMid exceeds domain min or max.",u),i.splice(a,0,u))),t.domain(fh(o,i,n)),o===Xs&&t.unknown(e.domainImplicit?ps:void 0),e.nice&&t.nice&&t.nice(e.nice!==!0&&sh(t,e.nice)||null),i.length):0}function tv(t,e,n){return e?(t.domain(fh(t.type,e,n)),e.length):-1}function nv(t,e,n,r,i,o){var s=Math.abs(ke(n)-n[0]),a=s/(s-2*r),u=t===yt?xu(e,null,a):t===wr?Po(e,null,a,.5):t===br?Po(e,null,a,i||1):t===Ui?dd(e,null,a,o||1):Au(e,null,a);return e=e.slice(),e[0]=u[0],e[e.length-1]=u[1],e}function fh(t,e,n){if(_l(t)){var r=Math.abs(e.reduce(function(i,o){return i+(o<0?-1:o>0?1:0)},0));r!==e.length&&n.warn("Log scale domain includes zero: "+ci(e))}return e}function rv(t,e,n){let r=e.bins;if(r&&!Fe(r)){const i=(r.start==null||r.stop==null)&&t.domain(),o=r.start==null?i[0]:r.start,s=r.stop==null?ke(i):r.stop,a=r.step;a||Y("Scale bins parameter missing step property."),r=Kn(o,s+a,a)}return r?t.bins=r:t.bins&&delete t.bins,t.type===Ks&&(r?!e.domain&&!e.domainRaw&&(t.domain(r),n=r.length):t.bins=t.domain()),n}function iv(t,e,n){var r=t.type,i=e.round||!1,o=e.range;if(e.rangeStep!=null)o=ov(r,e,n);else if(e.scheme&&(o=sv(r,e,n),ge(o))){if(t.interpolator)return t.interpolator(o);Y(`Scale type ${r} does not support interpolating color schemes.`)}if(o&&Qi(r))return t.interpolator(ji(Za(o,e.reverse),e.interpolate,e.interpolateGamma));o&&e.interpolate&&t.interpolate?t.interpolate($l(e.interpolate,e.interpolateGamma)):ge(t.round)?t.round(i):ge(t.rangeRound)&&t.interpolate(i?xr:At),o&&t.range(Za(o,e.reverse))}function ov(t,e,n){t!==Zl&&t!==Zs&&Y("Only band and point scales support rangeStep.");var r=(e.paddingOuter!=null?e.paddingOuter:e.padding)||0,i=t===Zs?1:(e.paddingInner!=null?e.paddingInner:e.padding)||0;return[0,e.rangeStep*Ys(n,i,r)]}function sv(t,e,n){var r=e.schemeExtent,i,o;return Fe(e.scheme)?o=ji(e.scheme,e.interpolate,e.interpolateGamma):(i=e.scheme.toLowerCase(),o=Js(i),o||Y(`Unrecognized scheme name: ${e.scheme}`)),n=t===Xl?n+1:t===Ks?n-1:t===Ws||t===Wl?+e.schemeCount||Zw:n,Qi(t)?hh(o,r,e.reverse):ge(o)?mA(hh(o,r),n):t===Xs?o:o.slice(0,n)}function hh(t,e,n){return ge(t)&&(e||n)?gA(t,Za(e||[0,1],n)):t}function Za(t,e){return e?t.slice().reverse():t}const dh=oe(",d");function av(t,e){return t.chrom+":"+dh(Math.floor(t.pos+1))+"-"+(t.chrom!=e.chrom?e.chrom+":":"")+dh(Math.ceil(e.pos))}const uv="https://genomespy.app/data/genomes/";class cv{constructor(e){if(this.config=e,!this.config.contigs&&typeof this.config.name!="string")throw new Error("No name has been defined for the genome assembly!");this.chromosomes=[],this.cumulativeChromPositions=new Map,this.chromosomesByName=new Map,this.startByIndex=[],this.totalSize=0,this.config.contigs&&this.setChromSizes(this.config.contigs)}get name(){return this.config.name}async load(e){if(!this.config.contigs){this.config.baseUrl?this.baseUrl=/^http(s)?/.test(this.config.baseUrl)?this.config.baseUrl:e+"/"+this.config.baseUrl:this.baseUrl=uv;try{this.setChromSizes(lv(await Si({baseURL:this.baseUrl}).load(`${this.config.name}/${this.name}.chrom.sizes`)))}catch(n){throw new Error(`Could not load chrom sizes: ${n.message}`)}}}setChromSizes(e){let n=0;this.startByIndex=[0];for(let r=0;r<e.length;r++){this.startByIndex.push(n);const i=e[r].size,o={...e[r],continuousStart:n,continuousEnd:n+i,continuousInterval:[n,n+i],index:r,number:r+1,odd:!(r&1)};this.chromosomes.push(o);const s=o.name.replace(/^chr/i,"");for(const a of["chr"+s,"CHR"+s,"Chr"+s,o.number,""+o.number,s,o.name])this.cumulativeChromPositions.set(a,n),this.chromosomesByName.set(a,o);n+=o.size}this.totalSize=n}getExtent(){return[0,this.totalSize]}toContinuous(e,n){let r=this.cumulativeChromPositions.get(e);if(r===void 0)throw new Error("Unknown chromosome/contig: "+e);return r+ +n}toChromosome(e){if(e>=this.totalSize)return;e=Math.floor(e);const n=sn(this.startByIndex,e)-1;if(n>0&&n<=this.chromosomes.length)return this.chromosomes[n-1]}toChromosomal(e){const n=this.toChromosome(e);if(n)return{chrom:n.name,pos:Math.floor(e)-n.continuousStart}}getChromosome(e){return this.chromosomesByName.get(e)}formatInterval(e){return av(...this.toChromosomalInterval(e))}toChromosomalInterval(e){const n=this.toChromosomal(e[0]+.5),r=this.toChromosomal(e[1]-.5);return r.pos+=1,[n,r]}toContinuousInterval(e){var i;let[n,r]=e;return r||(r=n),[this.toContinuous(n.chrom,n.pos??0),this.toContinuous(r.chrom,r.pos??((i=this.chromosomesByName.get(r.chrom))==null?void 0:i.size))]}parseInterval(e){const n=e.match(/^(chr[0-9A-Z]+)(?::([0-9,]+)(?:-(?:(chr[0-9A-Z]+):)?([0-9,]+))?)?$/);if(n){const r=n[1];if(n.slice(2).every(a=>a===void 0)){const a=this.getChromosome(r);return a?[a.continuousStart,a.continuousEnd]:void 0}const i=n[3]||r,o=parseInt(n[2].replace(/,/g,"")),s=n[4]!==void 0?parseInt(n[4].replace(/,/g,"")):o;return[this.toContinuous(r,o-1),this.toContinuous(i,s)]}}}function lv(t){return Pd(t).filter(e=>/^chr[0-9A-Z]+$/.test(e[0])).map(([e,n])=>({name:e,size:parseInt(n)}))}function ph(t){return Le(t)&&"chrom"in t}function fv(t){return t.every(ph)}class Kr extends Array{constructor(){super(),this.type=void 0}extend(e){return this}extendAll(e){if(e instanceof Kr&&e.type!=this.type)throw new Error(`Cannot combine different types of domains: ${this.type} and ${e.type}`);for(const n of e)this.extend(n);return this}extendAllWithAccessor(e,n){for(const r of e)this.extend(n(r));return this}}class Ka extends Kr{constructor(){super(),this.type="quantitative"}extend(e){return e==null||Number.isNaN(e)?this:(e=+e,this.length?e<this[0]?this[0]=e:e>this[1]&&(this[1]=e):(this.push(e),this.push(e)),this)}}class gh extends Kr{constructor(){super(),this.type="ordinal",this.uniqueValues=new Set}extend(e){return e==null||Number.isNaN(e)?this:(this.uniqueValues.has(e)||(this.uniqueValues.add(e),this.push(e)),this)}}class mh extends gh{constructor(){super(),this.type="nominal"}}class hv extends Kr{constructor(e){super();let n=0;for(let r=1;r<e.length;r++)n+=Math.sign(e[r]-e[r-1]);if(Math.abs(n)!=e.length-1)throw new Error("Piecewise domain must be strictly increasing or decreasing: "+JSON.stringify(e));e.forEach(r=>this.push(r))}extend(e){if(this.includes(e))return this;throw new Error("Piecewise domains are immutable and cannot be unioned!")}}const Ah={quantitative:Ka,index:Ka,locus:Ka,nominal:mh,ordinal:gh};function xh(t,e){if(t=="quantitative"&&dv(e)){const n=new hv(e);return n.type=t,n}else if(Ah[t]){const n=new Ah[t];return n.type=t,e&&n.extendAll(e),n}throw new Error("Unknown type: "+t)}function dv(t){return t&&t.length>0&&t.length!=2&&t.every(e=>typeof e=="number")}function pv(t){return((t*=2)<=1?t*t:--t*(2-t)+1)/2}const yh="quantitative",bh="ordinal",wh="nominal",vh="locus",gv="index";class mv{constructor(e){this.channel=e,this.members=[],this.type=null,this._zoomExtent=void 0,this._domainListeners=new Set,this.name=void 0,this._scale=void 0}addEventListener(e,n){if(e!="domain")throw new Error("Unsupported event type: "+e);this._domainListeners.add(n)}removeEventListener(e,n){if(e!="domain")throw new Error("Unsupported event type: "+e);this._domainListeners.delete(n)}_notifyDomainListeners(){for(const e of this._domainListeners.values())e({type:"domain",scaleResolution:this})}pushUnitView(e,n){var s;const r=aa(e,n),i=r.type,o=(s=r==null?void 0:r.scale)==null?void 0:s.name;if(o){if(this.name!==void 0&&o!=this.name)throw new Error(`Shared scales have conflicting names: "${o}" vs. "${this.name}"!`);this.name=o}if(!this.type)this.type=i;else if(i!==this.type&&!Nr(n))throw new Error(`Can not use shared scale for different data types: ${this.type} vs. ${i}. Use "resolve: independent" for channel ${this.channel}`);this.members.push({view:e,channel:n})}isExplicitDomain(){return!!this.getConfiguredDomain()}_getMergedScaleProps(){return Ln(this,"mergedScaleProps",()=>{const e=this.members.map(n=>aa(n.view,n.channel).scale).filter(n=>n!==void 0);return Eo(e,"scale",["domain"])})}getScaleProps(){return Ln(this,"scaleProps",()=>{const e=this._getMergedScaleProps();if(e===null||e.type=="null")return{type:"null"};const n={...this._getDefaultScaleProperties(this.type),...e};n.type||(n.type=Av(this.channel,this.type));const r=this.getInitialDomain();return r&&r.length>0?n.domain=r:Yt(n.type)&&(n.domain=new mh),!n.domain&&n.domainMid!==void 0&&(n.domain=[n.domainMin??0,n.domainMax??1]),this.channel=="y"&&Yt(n.type)&&n.reverse==null&&(n.reverse=!0),n.range&&n.scheme&&delete n.scheme,!("zoom"in n)&&["index","locus"].includes(n.type)&&(n.zoom=!0),xv(n,this.channel),n})}getInitialDomain(){return this.getConfiguredDomain()??(this.type==vh?this.getGenome().getExtent():this.getDataDomain())}getConfiguredDomain(){return this._reduceDomains(e=>Nr(e.channel)?void 0:e.view.getConfiguredDomain(e.channel))}getDataDomain(){return this._reduceDomains(e=>Nr(e.channel)?void 0:e.view.extractDataDomain(e.channel))}reconfigure(){if(this._scale&&this._scale.type!="null"){V0(this,"scaleProps");const e=this.getScaleProps();lh(e,this._scale),Te(this._scale.type)&&(this._zoomExtent=this._getZoomExtent())}}getScale(){if(this._scale)return this._scale;const e=this.getScaleProps(),n=Jw(e);return this._scale=n,rm(n)&&n.genome(this.getGenome()),Te(n.type)&&(this._zoomExtent=this._getZoomExtent()),n}getDomain(){return this.getScale().domain()}getComplexDomain(){var e;return((e=this.getGenome())==null?void 0:e.toChromosomalInterval(this.getDomain()))??this.getDomain()}isZoomed(){return this.isZoomable()&&rf(this.getInitialDomain(),this.getDomain())}isZoomable(){if(!yf(this.channel))return!1;const e=this.getScale().type;return["linear","locus","index","log","pow","sqrt"].includes(e)?!!this.getScaleProps().zoom:!1}zoom(e,n,r){if(!this.isZoomable())return!1;const i=this.getScale(),o=i.domain();let s=[...o],a=i.invert(n);switch(this.getScaleProps().reverse&&(r=-r),"align"in i&&(a+=i.align()),i.type){case"linear":case"index":case"locus":s=ld(s,r||0),s=Au(s,a,e);break;case"log":s=fd(s,r||0),s=xu(s,a,e);break;case"pow":case"sqrt":{const u=i;s=hd(s,r||0,u.exponent()),s=Po(s,a,e,u.exponent());break}default:throw new Error("Zooming is not implemented for: "+i.type)}return this._zoomExtent&&(s=pd(s,this._zoomExtent[0],this._zoomExtent[1])),[0,1].some(u=>s[u]!=o[u])?(i.domain(s),this._notifyDomainListeners(),!0):!1}async zoomTo(e,n=!1){var a;if(ai(n)&&(n=n?700:0),!this.isZoomable())throw new Error("Not a zoomable scale!");const r=this.fromComplexInterval(e),i=(a=this.members[0])==null?void 0:a.view.context.animator,o=this.getScale(),s=o.domain();if(n>0&&s.length==2){const u=s[1]-s[0],c=s[0]+u/2,f=r[1]-r[0],l=r[0]+f/2,h=yl([c,0,u],[l,0,f]).rho(.7);await i.transition({duration:n/1e3*h.duration,easingFunction:pv,onUpdate:p=>{const[d,,g]=h(p);o.domain([d-g/2,d+g/2]),this._notifyDomainListeners()}}),o.domain(r),this._notifyDomainListeners()}else o.domain(r),i==null||i.requestRender(),this._notifyDomainListeners()}resetZoom(){if(!this.isZoomable())throw new Error("Not a zoomable scale!");const e=this.getDomain(),n=this.getInitialDomain();return[0,1].some(r=>n[r]!=e[r])?(this._scale.domain(n),this._notifyDomainListeners(),!0):!1}getZoomLevel(){return this.isZoomable()?ui(this._zoomExtent)/ui(this.getScale().domain()):1}_getZoomExtent(){const e=this.getScaleProps(),n=e.zoom;if(yv(n)&&Fe(n.extent))return this.fromComplexInterval(n.extent);if(n)return e.type=="locus"?this.getGenome().getExtent():this._scale.domain()}_getDefaultScaleProperties(e){const n=this.channel,r={};return this.isExplicitDomain()&&(r.zero=!1),kr(n)?r.nice=!this.isExplicitDomain():Kt(n)?r.scheme=e==wh?"tableau10":e==bh?"blues":"viridis":qi(n)?r.range=wf(n):n=="size"?r.range=[0,400]:n=="angle"&&(r.range=[0,360]),r}getGenome(){var n;if(this.type!=="locus")return;const e=(n=this.members[0].view.context.genomeStore)==null?void 0:n.getGenome();if(!e)throw new Error("No genome has been defined!");return e}invertToComplex(e){const n=this.getScale();if("invert"in n){const r=n.invert(e);return this.toComplex(r)}else throw new Error("The scale does not support inverting!")}toComplex(e){const n=this.getGenome();return n?n.toChromosomal(e):e}fromComplex(e){return ph(e)?this.getGenome().toContinuous(e.chrom,e.pos):e}fromComplexInterval(e){return this.type==="locus"&&fv(e)?this.getGenome().toContinuousInterval(e):e}_getViewPaths(){return this.members.map(e=>e.view.getPathString()).join(", ")}_reduceDomains(e){const n=this.members.map(e).filter(r=>!!r);if(n.length)return n.reduce((r,i)=>r.extendAll(i))}}function Av(t,e){if(e==gv||e==vh){if(yf(t))return e;throw new Error(`${t} does not support ${e} data type. Only positional channels do.`)}const n={x:["band","band","linear"],y:["band","band","linear"],size:[void 0,"point","linear"],opacity:[void 0,"point","linear"],fillOpacity:[void 0,"point","linear"],strokeOpacity:[void 0,"point","linear"],color:["ordinal","ordinal","linear"],fill:["ordinal","ordinal","linear"],stroke:["ordinal","ordinal","linear"],strokeWidth:[void 0,void 0,"linear"],shape:["ordinal","ordinal",void 0],dx:[void 0,void 0,"null"],dy:[void 0,void 0,"null"],angle:[void 0,void 0,"linear"]},i=["uniqueId","facetIndex","semanticScore","search","text","sample"].includes(t)?"null":n[t]?n[t][[wh,bh,yh].indexOf(e)]:e==yh?"linear":"ordinal";if(i===void 0)throw new Error(`Channel "${t}" is not compatible with "${e}" data type. Use of a proper scale may be needed.`);return i}function xv(t,e){kr(e)&&t.type!=="ordinal"&&(t.range=[0,1]),e=="opacity"&&Te(t.type)&&(t.clamp=!0)}function yv(t){return Le(t)}function qa(...t){for(const e of t)if(e!==void 0)return e}class bv{constructor(e){this.channel=e,this.members=[]}get scaleResolution(){var e;return(e=vn(this.members))==null?void 0:e.view.getScaleResolution(this.channel)}pushUnitView(e,n){const r=e.getScaleResolution(this.channel);if(!r)throw new Error("Cannot find a scale resolution!");if(this.scaleResolution&&r!==this.scaleResolution)throw new Error("Shared axes must have a shared scale!");this.members.push({view:e,channel:n})}getAxisProps(){return Ln(this,"axisProps",()=>{const e=this.members.map(n=>{const r=n.view.mark.encoding[n.channel];return"axis"in r&&r.axis});return e.length>0&&e.some(n=>n===null)?null:Eo(e.filter(n=>n!==void 0),"axis",["title"])})}getTitle(){const e=o=>{var a;const s=aa(o.view,o.channel);if(!Ge(s))return{member:o,explicitTitle:qa((a=s.axis)==null?void 0:a.title,s.title),implicitTitle:qa(Pr(s)?s.field:void 0,ua(s)?s.expr:void 0)}},n=this.members.map(e),r=n.filter(o=>{var s;if(Nr(o.member.channel)&&!o.explicitTitle){const a=Cn(o.member.channel);return((s=n.find(u=>u.member.view==o.member.view&&u.member.channel==a))==null?void 0:s.explicitTitle)===void 0}return!0}),i=new Set(r.map(o=>qa(o.explicitTitle,o.implicitTitle)).filter(W));return i.size?[...i].join(", "):null}}class Ch extends ih{constructor(e,n,r,i){super(e,n,r,i),this.spec=e}}class tn extends kn{constructor(e,n,r,i){super(e,n,r,i),this.spec=e,this.children=(e.layer||[]).map((o,s)=>{if(nu(o)||tu(o))return n.createView(o,this,"layer"+s);throw new Error("LayerView accepts only unit or layer specs as children!")})}*[Symbol.iterator](){for(const e of this.children)yield e}render(e,n,r={}){if(this.isVisible()){e.pushView(this,n);for(const i of this.children)i.render(e,n,r);e.popView(this)}}propagateInteractionEvent(e){this.handleInteractionEvent(void 0,e,!0),this.children.length&&this.children.at(-1).propagateInteractionEvent(e),!e.stopped&&this.handleInteractionEvent(void 0,e,!1)}}class Eh{constructor(e,n){this.n=e,this.maxCols=n??1/0}get nRows(){return this.maxCols==1/0?1:Math.ceil(this.n/this.maxCols)}get nCols(){return Math.min(this.n,this.maxCols)}get rowIndices(){const e=[],n=this.nCols,r=this.nRows;for(let i=0;i<r;i++){const o=[];e.push(o);for(let s=0;s<n;s++){const a=i*n+s;a<this.n&&o.push(a)}}return e}get colIndices(){const e=[],n=this.nCols,r=this.nRows;for(let i=0;i<n;i++){const o=[];e.push(o);for(let s=0;s<r;s++){const a=s*n+i;a<this.n&&o.push(a)}}return e}getCellIndex(e,n){let r=0;if(this.maxCols==1/0)r=n==0?e:void 0;else{if(e>=this.maxCols)return;r=n*this.nCols+e}return r<this.n?r:void 0}getCellCoords(e){if(!(e<0||e>=this.n))return[e%this.nCols,Math.floor(e/this.nCols)]}}function ut(t){return()=>t}const ct=class{static create(e,n,r,i){return new ct(ut(e),ut(n),ut(r),ut(i))}_offset(e,n){const r=this["_"+e];if(n===0)return r;switch(typeof n){case"number":return()=>r()+n;case"function":return()=>r()+n();default:throw new Error("Not a number of function")}}_passThrough(e){return this._offset(e,0)}constructor(e,n,r,i){this._x=e,this._y=n,this._width=r,this._height=i}get x(){return this._x()}get y(){return this._y()}get width(){return this._width()}get height(){return this._height()}get x2(){return this._x()+this._width()}get y2(){return this._y()+this._height()}equals(e){return e?this===e||this.x===e.x&&this.y===e.y&&this.width===e.width&&this.height===e.height:!1}modify(e){if(!Object.keys(e).length)return this;const n=r=>{const i=e[r];return typeof i=="number"?ut(i):typeof i=="function"?i:this._passThrough(r)};return new ct(n("x"),n("y"),n("width"),n("height"))}translate(e,n){return e===0&&n===0?this:new ct(this._offset("x",e),this._offset("y",n),this._passThrough("width"),this._passThrough("height"))}translateBy(e){return this.translate(e.x,e.y)}expand(e,n=1){return e.left==0&&e.top==0&&e.right==0&&e.bottom==0?this:new ct(e.left?this._offset("x",-e.left*n):this._passThrough("x"),e.top?this._offset("y",-e.top*n):this._passThrough("y"),e.width?this._offset("width",e.width*n):this._passThrough("width"),e.height?this._offset("height",e.height*n):this._passThrough("height"))}shrink(e){return this.expand(e,-1)}intersect(e){return this===e?this:new ct(()=>Math.max(this.x,e.x),()=>Math.max(this.y,e.y),()=>Math.min(this.x2,e.x2)-Math.max(this.x,e.x),()=>Math.min(this.y2,e.y2)-Math.max(this.y,e.y))}isDefined(){return this.width>=0&&this.height>=0}flatten(){return new ct(ut(this.x),ut(this.y),ut(this.width),ut(this.height))}containsPoint(e,n){return e>=this.x&&e<this.x2&&n>=this.y&&n<this.y2}normalizePoint(e,n){return{x:(e-this.x)/this.width,y:(n-this.y)/this.height}}toString(){return`Rectangle: x: ${this.x}, y: ${this.y}, width: ${this.width}, height: ${this.height}`}};let zn=ct;$h(zn,"ZERO",ct.create(0,0,0,0));function wv(t,e,n){return n=(n-t)/(e-t),n=Math.max(0,Math.min(1,n)),n*n*(3-2*n)}class On extends q{get identifier(){}handle(e){throw new Error("Source does not handle incoming data!")}async load(){}}function Sh(t){const e={...t.format};if(e.type??(e.type=Sv(t)&&vv(t.url)),e.parse??(e.parse="auto"),!e.type)throw new Error("Format for the data source was not defined and it could not be inferred: "+JSON.stringify(t));return e}function vv(t){var e;if(Array.isArray(t)&&(t=t[0]),t)return(e=t.match(/\.(csv|tsv|json)/))==null?void 0:e[1]}const So=t=>typeof t!="object"?Cv:Ev,Cv=t=>({data:t}),Ev=t=>t;function Sv(t){return"url"in t}function Dv(t){return"dynamicCallbackSource"in t}class Dh extends On{constructor(e){super(),this.callback=e}loadSynchronously(){if(!this.callback)return;const e=this.callback();if(!e||typeof e[Symbol.iterator]!="function")throw new Error("Dynamic data callback didn't return iterable data!");this.reset(),this.beginBatch({type:"file"});let n;for(const r of e)n||(n=So(r)),this._propagate(n(r));this.complete()}async load(){this.loadSynchronously()}}const Bh="chromosome_ticks_and_labels",Fh={x:"width",y:"height"};function Ja(t){return t=="x"?"y":"x"}const _a={x:["bottom","top"],y:["left","right"]},Mh=Object.fromEntries(Object.entries(_a).map(([t,e])=>e.map(n=>[n,t])).flat(1));function nn(t){return Mh[t]}class Bv extends tn{constructor(e,n,r,i){const o=n=="locus",s={...o?Iv:Ih,...Mv(n,e),...e};if(super(o?Tv(s):Th(s),r,i,`axis_${e.orient}`),this.axisProps=s,this.axisUpdateRequested=!0,this._addBroadcastHandler("layout",()=>{this.axisUpdateRequested=!0}),this.previousScaleDomain=[],this.axisLength=void 0,this.ticks=[],this.tickSource=new Dh(()=>this.ticks),o){const a=nn(this.axisProps.orient),u=this.getScaleResolution(a).getGenome();this.findChildByName(Bh).getDynamicDataSource=()=>new Dh(()=>u.chromosomes)}this.blockEncodingInheritance=!0}getOrient(){return this.axisProps.orient}getSize(){const e={px:this.getPerpendicularSize()},n={grow:1};return Mh[this.axisProps.orient]=="x"?new en(n,e):new en(e,n)}getPerpendicularSize(){return $a(this.axisProps)}getDynamicDataSource(){return this.tickSource}_updateAxisData(){const e=nn(this.axisProps.orient),n=this.getScaleResolution(e).getScale(),r=n.domain();if(rf(r,this.previousScaleDomain)&&!this.axisUpdateRequested)return;this.previousScaleDomain=r;const i=this.ticks,o=Fv(this.axisProps,n,this.axisLength,i);o!==i&&(this.ticks=o,this.tickSource.loadSynchronously()),this.axisUpdateRequested=!1}onBeforeRender(){super.onBeforeRender(),this._updateAxisData()}render(e,n,r={}){this.isVisible()&&(this.axisLength=n[Fh[nn(this.getOrient())]],super.render(e,n,r))}isPickingSupported(){return!1}}function $a(t){const e=nn(t.orient);let n=t.ticks&&t.tickSize||0;return t.labels&&(n+=t.labelPadding,e=="x"?n+=t.labelFontSize:n+=30),t.title&&(n+=t.titlePadding+t.titleFontSize),n=Math.min(t.maxExtent||1/0,Math.max(t.minExtent||0,n)),n}function Fv(t,e,n,r=[]){const i=a=>25+60*wv(100,700,a);let o=me(t.tickCount)?t.tickCount:Math.round(n/i(n));o=sh(e,o,t.tickMinStep);const s=t.values?ah(e,t.values,o):Gw(e,o);if(wA(s,r,a=>a,a=>a.value))return r;{const a=Hw(e,o,t.format);return s.map(u=>({value:u,label:a(u)}))}}const Ih={values:null,minExtent:20,maxExtent:1/0,offset:0,domain:!0,domainWidth:1,domainColor:"gray",domainDash:null,domainDashOffset:0,domainCap:"square",ticks:!0,tickSize:5,tickWidth:1,tickColor:"gray",tickDash:null,tickDashOffset:0,tickCap:"square",tickCount:null,tickMinStep:null,labels:!0,labelAlign:"center",labelBaseline:"middle",labelPadding:4,labelFontSize:10,labelLimit:180,labelColor:"black",format:null,titleColor:"black",titleFont:"sans-serif",titleFontSize:10,titlePadding:3};function Mv(t,e){const n=e.orient,r=t=="nominal"||t=="ordinal";let i="center",o="middle",s=e.labelAngle??((n=="top"||n=="bottom")&&r?-90:0);switch(n){case"left":i="right";break;case"right":i="left";break;case"top":case"bottom":Math.abs(s)>30?(i=s>0==(n=="bottom")?"left":"right",o="middle"):o=n=="top"?"alphabetic":"top";break}return{labelAlign:i,labelAngle:s,labelBaseline:o}}function Th(t){const e={...t,extent:$a(t)},n=nn(e.orient),r=Ja(n),i=e.orient=="bottom"||e.orient=="right"?1:-1,o=e.orient=="bottom"||e.orient=="left"?1:0,s=()=>({name:"domain",data:{values:[0]},mark:{type:"rule",clip:!1,strokeDash:e.domainDash,strokeCap:e.domainCap,color:e.domainColor,[r]:o,size:e.domainWidth}}),a=()=>({name:"labels",mark:{type:"text",clip:!1,align:e.labelAlign,angle:e.labelAngle,baseline:e.labelBaseline,[r+"Offset"]:(e.tickSize+e.labelPadding)*i,[r]:o,size:e.labelFontSize,color:e.labelColor,minBufferSize:1500},encoding:{[n]:{field:"value",type:"quantitative"},text:{field:"label"}}}),u=()=>({name:"ticks",mark:{type:"rule",clip:!1,strokeDash:e.tickDash,strokeCap:e.tickCap,color:e.tickColor,size:e.tickWidth,minBufferSize:300},encoding:{[r]:{value:o},[r+"2"]:{value:o-e.tickSize/e.extent*(o?1:-1)}}}),c=()=>({name:"title",data:{values:[0]},mark:{type:"text",clip:!1,align:"center",baseline:e.orient=="bottom"?"bottom":"top",angle:[0,90,0,-90][["top","right","bottom","left"].indexOf(e.orient)],text:e.title,color:e.titleColor,[n]:.5,[r]:1-o}}),f=()=>{const h={name:"ticks_and_labels",encoding:{[n]:{field:"value",type:"quantitative"}},layer:[]};return e.ticks&&h.layer.push(u()),e.labels&&h.layer.push(a()),h},l={[Fh[Ja(nn(e.orient))]]:e.extent,data:{dynamicCallbackSource:!0},layer:[]};return e.domain&&l.layer.push(s()),(e.ticks||e.labels)&&l.layer.push(f()),e.title&&l.layer.push(c()),l}const Iv={...Ih,chromTicks:!0,chromTickSize:18,chromTickWidth:1,chromTickColor:"#989898",chromTickDash:[4,2],chromTickDashOffset:1,chromLabels:!0,chromLabelFontSize:13,chromLabelFontWeight:"normal",chromLabelFontStyle:"normal",chromLabelColor:"black",chromLabelAlign:"left",chromLabelPadding:7};function Tv(t){const e={...t,extent:$a(t)},n=nn(e.orient),r=Ja(n),i=e.orient=="bottom"||e.orient=="left"?1:0,o=()=>({name:"chromosome_ticks",mark:{type:"rule",strokeDash:t.chromTickDash,strokeDashOffset:t.chromTickDashOffset,[r]:i,[r+"2"]:i-e.chromTickSize/e.extent*(i?1:-1),color:t.chromTickColor,size:e.chromTickWidth}}),s=()=>{let c;switch(e.orient){case"top":c={y:0,angle:0,paddingX:4,dy:-e.chromLabelPadding,viewportEdgeFadeWidthLeft:20,viewportEdgeFadeWidthRight:20,viewportEdgeFadeDistanceRight:-10,viewportEdgeFadeDistanceLeft:-20};break;case"bottom":c={y:1,angle:0,paddingX:4,dy:e.chromLabelPadding+e.chromLabelFontSize*.73,viewportEdgeFadeWidthLeft:20,viewportEdgeFadeWidthRight:20,viewportEdgeFadeDistanceRight:-10,viewportEdgeFadeDistanceLeft:-20};break;case"left":c={x:1,angle:-90,paddingY:4,dy:-e.chromLabelPadding,viewportEdgeFadeWidthBottom:20,viewportEdgeFadeWidthTop:20,viewportEdgeFadeDistanceBottom:-20,viewportEdgeFadeDistanceTop:-10};break;case"right":c={x:0,angle:90,align:"right",paddingY:4,dy:-e.chromLabelPadding};break;default:c={}}return{name:"chromosome_labels",mark:{type:"text",size:e.chromLabelFontSize,font:e.chromLabelFont,fontWeight:e.chromLabelFontWeight,fontStyle:e.chromLabelFontStyle,color:e.chromLabelColor,align:t.chromLabelAlign,baseline:"alphabetic",clip:!1,...c},encoding:{[n+"2"]:{field:"continuousEnd",type:"locus"},text:{field:"name"}}}};let a;switch(e.orient){case"bottom":case"top":a={};break;case"left":a={labelAngle:-90,labelAlign:"center",labelPadding:6};break;case"right":a={labelAngle:90,labelAlign:"center",labelPadding:6};break;default:a={}}const u=Th({...t,...a});if(t.chromTicks||t.chromLabels){const c={name:Bh,data:{dynamicCallbackSource:!0},encoding:{[n]:{field:"continuousStart",type:"locus",band:0}},layer:[]};if(t.chromTicks&&c.layer.push(o()),t.chromLabels){c.layer.push(s());let f;u.layer.filter(l=>l.name=="ticks_and_labels").forEach(l=>l.layer.filter(h=>h.name=="labels").forEach(h=>{f=h.mark})),f&&(e.orient=="top"||e.orient=="bottom"?(f.viewportEdgeFadeWidthLeft=30,f.viewportEdgeFadeDistanceLeft=40):(f.viewportEdgeFadeWidthBottom=30,f.viewportEdgeFadeDistanceBottom=40))}u.layer.push(c)}return u}const Ph={anchor:"middle",frame:"group",offset:10,orient:"top",align:void 0,angle:0,baseline:"alphabetic",dx:0,dy:0,color:void 0,font:void 0,fontSize:12,fontStyle:"normal",fontWeight:"normal"},Pv={orient:"left",anchor:"middle",align:"right",baseline:"middle",angle:0,fontSize:12},Rv={orient:"top",anchor:"start",align:"left",baseline:"top",offset:-10,dx:10,fontSize:12},Lv={start:0,middle:.5,end:1},kv={start:"left",middle:"center",end:"right"};function Nv(t){if(!t)return;const e=W(t)?{text:t}:t;if(!e.text||e.orient=="none")return;const n={"track-title":Pv,overlay:Rv}[e.style]??{},r={...Ph,...n,...e};let i={},o={x:0,y:0};const s=Lv[r.anchor??"middle"];switch(r.orient){case"top":o={x:s,y:1},i={baseline:"alphabetic",angle:0};break;case"right":o={x:1,y:1-s},i={baseline:"alphabetic",angle:90};break;case"bottom":o={x:s,y:0},i={baseline:"top",angle:0};break;case"left":o={x:0,y:s},i={baseline:"alphabetic",angle:-90};break}const a={...Ph,...i,...n,...e},u={xOffset:0,yOffset:0};switch(r.orient){case"top":u.yOffset=-a.offset;break;case"right":u.xOffset=a.offset;break;case"bottom":u.yOffset=a.offset;break;case"left":u.xOffset=-a.offset;break}return{configurableVisibility:!1,data:{values:[{}]},mark:{type:"text",tooltip:null,clip:!1,...o,...u,text:a.text,align:a.align??kv[a.anchor],angle:a.angle,baseline:a.baseline,dx:a.dx,dy:a.dy,color:a.color,font:a.font,size:a.fontSize,fontStyle:a.fontStyle,fontWeight:a.fontWeight}}}function zv(t,e,n,r){if(t.type=="wheel"){t.uiEvent.preventDefault();const i=t.uiEvent,o=i.deltaMode?120:1;let{x:s,y:a}=t.point;if(r){const u=r.mark.encoders;u.x&&!u.x2&&(s=+u.x(r.datum)*e.width+e.x),u.y&&!u.y2&&(a=(1-+u.y(r.datum))*e.height+e.y)}Math.abs(i.deltaX)<Math.abs(i.deltaY)?n({x:s,y:a,xDelta:0,yDelta:0,zDelta:i.deltaY*o/300}):n({x:s,y:a,xDelta:-i.deltaX*o,yDelta:0,zDelta:0})}else if(t.type=="mousedown"&&t.uiEvent.button===0){const i=t.uiEvent;i.preventDefault();let o=i;const s=u=>{n({x:o.clientX,y:o.clientY,xDelta:u.clientX-o.clientX,yDelta:u.clientY-o.clientY,zDelta:0}),o=u},a=u=>{document.removeEventListener("mousemove",s),document.removeEventListener("mouseup",a)};document.addEventListener("mouseup",a,!1),document.addEventListener("mousemove",s,!1)}}class Rh extends kn{constructor(n,r,i,o,s){super(n,r,i,o);he(this,Jr);he(this,$e);he(this,Bo);he(this,Fo);he(this,rn);he(this,_r);he(this,$r);he(this,ei);he(this,Mo);he(this,Gn,1/0);he(this,Un,10);he(this,Re,[]);he(this,Hn,0);this.spec=n,Yn(this,Un,n.spacing??10),Yn(this,Gn,s),Yn(this,Re,[]),this.wrappingFacet=!1,this._createChildren()}_createChildren(){}appendChild(n){n.parent??(n.parent=this),Q(this,Re).push(ue(this,Jr,fu).call(this,n)),ed(this,Hn)._++}setChildren(n){for(const r of n)this.appendChild(r)}replaceChild(n,r){const i=Q(this,Re).findIndex(o=>o.view==n);if(i>=0)Q(this,Re)[i]=ue(this,Jr,fu).call(this,r);else throw new Error("Not my child view!")}get children(){return Q(this,Re).map(n=>n.view)}get childCount(){return Q(this,Re).length}onScalesResolved(){super.onScalesResolved(),ue(this,Fo,rd).call(this)}*[Symbol.iterator](){for(const n of Q(this,Re)){n.background&&(yield n.background);for(const r of Object.values(n.axes))r&&(yield r);yield n.view,n.title&&(yield n.title)}}getOverhang(){const n=ue(this,rn,ni).call(this,"column"),r=ue(this,rn,ni).call(this,"row");return!n.length||!r.length?Qe.zero():new Qe(r.at(0).axisBefore,n.at(-1).axisAfter,r.at(-1).axisAfter,n.at(0).axisBefore)}getSize(){return this._cache("size",()=>new en(ue(this,$r,du).call(this,"column"),ue(this,$r,du).call(this,"row")).subtractPadding(this.getOverhang()).addPadding(this.getPadding()))}render(n,r,i={}){if(!this.isVisible())return;this.parent||(r=r.shrink(this.getPadding())),n.pushView(this,r);const o={devicePixelRatio:this.context.glHelper.dpr},s=eh(ue(this,_r,hu).call(this,"column"),r.width,o),a=eh(ue(this,_r,hu).call(this,"row"),r.height,o),u=new Eh(Q(this,$e,Ft).length,Q(this,Gn)??1/0);for(const[c,f]of Q(this,$e,Ft).entries()){const{view:l,axes:h,background:p,title:d}=f,[g,m]=u.getCellCoords(c),A=s[ue(this,ei,pu).call(this,"column",g)],y=a[ue(this,ei,pu).call(this,"row",m)],b=l.getSize(),C=l.getPadding().subtract(l.getOverhang()),B=A.location+C.left,E=y.location+C.top,w=(b.width.grow?A.size:b.width.px)-C.width,X=(b.height.grow?y.size:b.height.px)-C.height,H=new zn(()=>r.x+B,()=>r.y+E,()=>w,()=>X);f.coords=H,p==null||p.render(n,H,i);const ae=Uv(l);ae&&l.render(n,H,i);for(const[M,Se]of Object.entries(h)){const _=Se.axisProps;let ve;const je=Se.getPerpendicularSize();M=="bottom"?ve=H.translate(0,H.height+_.offset).modify({height:je}):M=="top"?ve=H.translate(0,-je-_.offset).modify({height:je}):M=="left"?ve=H.translate(-je-_.offset,0).modify({width:je}):M=="right"&&(ve=H.translate(H.width+_.offset,0).modify({width:je})),Se.render(n,ve)}ae||l.render(n,H,i),d==null||d.render(n,H,{...i,clipRect:void 0})}n.popView(this)}propagateInteractionEvent(n){if(this.handleInteractionEvent(void 0,n,!0),n.stopped)return;const r=Q(this,$e,Ft).find(o=>o.coords.containsPoint(n.point.x,n.point.y)),i=r==null?void 0:r.view;i&&(i.propagateInteractionEvent(n),(i instanceof we||i instanceof tn)&&zv(n,r.coords,o=>ue(this,Mo,id).call(this,r.coords,r.view,o),this.context.getCurrentHover())),!n.stopped&&this.handleInteractionEvent(void 0,n,!1)}getDefaultResolution(n,r){return"independent"}}Gn=new WeakMap,Un=new WeakMap,Re=new WeakMap,Hn=new WeakMap,Jr=new WeakSet,fu=function(n){var i;const r={view:n,background:void 0,axes:{},coords:zn.ZERO};if(n instanceof we||n instanceof tn){const o=(i=n.spec)==null?void 0:i.view;if(o!=null&&o.fill||o!=null&&o.stroke){const a=new we(Ov(o),this.context,n,"background"+Q(this,Hn));a.blockEncodingInheritance=!0,r.background=a}const s=Nv(n.spec.title);if(s){const a=new we(s,this.context,n,"title"+Q(this,Hn));a.blockEncodingInheritance=!0,r.title=a}}return r},$e=new WeakSet,Ft=function(){return Q(this,Re).filter(n=>n.view.isVisible())},Bo=new WeakSet,nd=function(){return new Eh(Q(this,$e,Ft).length,Q(this,Gn)??1/0)},Fo=new WeakSet,rd=function(){if(Object.keys(this.resolutions.axis).length)throw new Error("ConcatView does not (currently) support shared axes!");for(const n of Q(this,Re)){const{view:r,axes:i}=n,o=(s,a,u)=>{const c=s.getAxisProps();if(c!==null){if(!c.orient){for(const f of _a[a])if(!i[f]){c.orient=f;break}if(!c.orient)throw new Error("No slots available for an axis! Perhaps a LayerView has more than two children?")}if(c.title??(c.title=s.getTitle()),!_a[a].includes(c.orient))throw new Error(`Invalid axis orientation "${c.orient}" on channel "${a}"!`);if(i[c.orient])throw new Error(`An axis with the orient "${c.orient}" already exists!`);i[c.orient]=new Bv(c,s.scaleResolution.type,this.context,u)}};if(r instanceof we||r instanceof tn)for(const s of["x","y"]){const a=r.resolutions.axis[s];a&&o(a,s,r)}if(r instanceof tn){for(const s of r.children)for(const[a,u]of Object.entries(s.resolutions.axis)){const c=u.getAxisProps();c&&c.orient&&o(u,a,s)}for(const s of r.children)for(const[a,u]of Object.entries(s.resolutions.axis)){const c=u.getAxisProps();c&&!c.orient&&o(u,a,s)}}}},rn=new WeakSet,ni=function(n){const r=n=="column"?["left","right"]:["top","bottom"],i=n=="column"?"width":"height",o=(s,a)=>s.map(u=>{const c=Q(this,$e,Ft)[u].axes[r[a]];if(c)return Math.max(c.getPerpendicularSize()+c.axisProps.offset,0);const f=Q(this,$e,Ft)[u].view.getOverhang();return n=="column"?a?f.right:f.left:a?f.bottom:f.top}).reduce((u,c)=>Math.max(u,c),0);return Q(this,Bo,nd)[n=="column"?"colIndices":"rowIndices"].map(s=>({axisBefore:o(s,0),axisAfter:o(s,1),view:Pw(s.map(a=>Q(this,$e,Ft)[a].view.getSize()[i]))}))},_r=new WeakSet,hu=function(n){const r=ue(this,rn,ni).call(this,n),i=[];i.push(Xr);for(const[o,s]of r.entries())o>0&&i.push({px:Q(this,Un),grow:0}),(o==0||this.wrappingFacet)&&i.push(Xr),i.push({px:s.axisBefore,grow:0}),i.push(s.view),i.push({px:s.axisAfter,grow:0}),(o==r.length-1||this.wrappingFacet)&&i.push(Xr);return i},$r=new WeakSet,du=function(n){let r=0,i=0;const o=(n=="row"&&this.spec.height)??(n=="column"&&this.spec.width);if(o||o===0)return th(o);const s=ue(this,rn,ni).call(this,n);for(const[a,u]of s.entries())a>0&&(i+=Q(this,Un)),(a==0||this.wrappingFacet)&&(i+=0),i+=u.axisBefore,i+=u.view.px??0,r+=u.view.grow??0,i+=u.axisAfter,(a==s.length-1||this.wrappingFacet)&&(i+=0);return{px:i,grow:r}},ei=new WeakSet,pu=function(n,r){return n=="row"&&this.wrappingFacet?1+6*r+2:2+4*r+1},Mo=new WeakSet,id=function(n,r,i){for(const[o,s]of Object.entries(Gv(r))){if(s.size<=0)continue;const a=n.normalizePoint(i.x,i.y),u=n.normalizePoint(i.x+i.xDelta,i.y+i.yDelta),c={x:u.x-a.x,y:u.y-a.y};for(const f of s)f.zoom(2**i.zDelta,o=="y"?1-a[o]:a[o],o=="x"?c.x:-c.y)}this.context.animator.requestRender()};function Ov(t){return{configurableVisibility:!1,data:{values:[{}]},mark:{fill:null,strokeWidth:1,fillOpacity:t.fill?1:0,...t,type:"rect",clip:!1,tooltip:null}}}function Gv(t){const e={x:new Set,y:new Set};return t.visit(n=>{for(const[r,i]of Object.entries(e)){const o=n.getScaleResolution(r);o&&o.isZoomable()&&i.add(o)}}),e}function Uv(t){let e=!0;return t.visit(n=>{n instanceof we&&e&&(e=n.mark.properties.clip)}),e}class eu extends Rh{constructor(e,n,r,i){super(e,n,r,i,iu(e)?e.columns:ru(e)?1:1/0),this.spec=e}_createChildren(){const e=this.spec,n=iu(e)?e.concat:ru(e)?e.vconcat:e.hconcat;this.setChildren(n.map((r,i)=>this.context.createView(r,this,"grid"+i)))}}class Hv{constructor(){this.types=[];const e=n=>(r,i,o,s)=>new n(r,i,o,r.name??s);this.addViewType(Qv,e(Ch)),this.addViewType(nu,e(tn)),this.addViewType(tu,e(we)),this.addViewType(ru,e(eu)),this.addViewType(jv,e(eu)),this.addViewType(iu,e(eu))}addViewType(e,n){this.types.push({specGuard:e,factory:n})}createView(e,n,r,i){const o=this.types.find(s=>s.specGuard(e));if(o)return o.factory(e,n,r,i??"unnamed");throw new Error("Invalid spec, cannot figure out the view type from the properties: "+JSON.stringify([...Object.keys(e)]))}isViewSpec(e){const n=this.types.filter(r=>r.specGuard(e));if(n.length>1)throw new Error("Ambiguous spec. Cannot create a view!");return n.length==1}}function tu(t){return"mark"in t&&(W(t.mark)||Le(t.mark))}function nu(t){return"layer"in t&&Le(t.layer)}function Lh(t){return t&&(tu(t)||nu(t))&&"aggregateSamples"in t}function Qv(t){return"import"in t}function ru(t){return"vconcat"in t&&Fe(t.vconcat)}function jv(t){return"hconcat"in t&&Fe(t.hconcat)}function iu(t){return"concat"in t&&Fe(t.concat)}const Vv={point:xw,rect:fw,rule:ww,link:Sw,text:Tw};class we extends kn{constructor(e,n,r,i){super(e,n,r,i),this.spec=e;const o=Vv[this.getMarkType()];if(o)this.mark=new o(this);else throw new Error(`No such mark: ${this.getMarkType()}`);this.sampleAggregateViews=[],this._initializeAggregateViews(),this.coords=void 0}*[Symbol.iterator](){for(const e of this.sampleAggregateViews)yield e}replaceChild(e,n){const r=this.sampleAggregateViews.indexOf(e);if(r>=0)this.sampleAggregateViews[r]=n;else throw new Error("Not my child view!")}render(e,n,r={}){this.isVisible()&&(this.coords=n,e.pushView(this,n),e.renderMark(this.mark,r),e.popView(this))}getMarkType(){return typeof this.spec.mark=="object"?this.spec.mark.type:this.spec.mark}resolve(e){const n=this.mark.encoding;for(const[r,i]of Object.entries(n)){if(!Pe(i))continue;let o=Cn(i.resolutionChannel??r);if(e=="axis"&&!kr(o))continue;let s=this;for(;s.parent instanceof kn&&["shared","excluded"].includes(s.parent.getConfiguredOrDefaultResolution(o,e))&&s.getConfiguredOrDefaultResolution(o,e)!="excluded";)s=s.parent;s.resolutions[e][o]||(s.resolutions[e][o]=e=="scale"?new mv(o):new bv(o)),kr(r)?s.resolutions[e][o].pushUnitView(this,r):e=="scale"&&s.resolutions[e][o].pushUnitView(this,r)}}getAccessor(e){return this._cache("accessor/"+e,()=>{const n=this.mark.encoding;if(n&&n[e])return this.context.accessorFactory.createAccessor(n[e])})}getFacetAccessor(e){const n=this.getAccessor("sample");return n||super.getFacetAccessor(this)}getCollector(){return this.context.dataFlow.findCollectorByKey(this)}_validateDomainQuery(e){if(Nr(e))throw new Error(`getDomain(${e}), must only be called for primary channels!`);const n=this.mark.encoding[e];if(!Pe(n))throw new Error("The channel has no scale, cannot get domain!");return n}getConfiguredDomain(e){const n=this._validateDomainQuery(e),r=n&&n.scale&&n.scale.domain;if(r){const i=this.getScaleResolution(n.resolutionChannel??e);return xh(n.type??"nominal",i.fromComplexInterval(r))}}extractDataDomain(e){const r=this._validateDomainQuery(e).type??"nominal",i=a=>{let u;const c=this.mark.encoding[a];if(c){const f=this.context.accessorFactory.createAccessor(c);if(f)if(u=xh(r),f.constant)u.extend(f({}));else{const l=this.getCollector();l!=null&&l.completed&&l.visitData(h=>u.extend(f(h)))}}return u};let o=i(e);const s=ca[e];if(s){const a=i(s);a&&o.extendAll(a)}return o}getZoomLevel(){const e=n=>{var r;return((r=this.getScaleResolution(n))==null?void 0:r.getZoomLevel())??1};return Lr.map(e).reduce((n,r)=>n*r,1)}_initializeAggregateViews(){if(Lh(this.spec))for(const e of this.spec.aggregateSamples){const n=e.transform??[];n.length&&vn(n).type!="collect"&&n.push({type:"collect"}),n.push({type:"mergeFacets"}),e.transform=n,e.encoding={...e.encoding??{},sample:null};const r=this.context.createView(e,this,"summaryView");r.getFacetFields=i=>{},this.sampleAggregateViews.push(r)}}propagateInteractionEvent(e){e.target=this}getDefaultResolution(e,n){return e=="x"?"shared":"independent"}}function*ou(t,e=[]){for(const[n,r]of t.entries())if(r instanceof Map)for(const i of ou(r,[...e,n]))yield i;else yield[[...e,n],r]}class su extends q{constructor(e){super(),this.params=e??{type:"collect"},this.observers=[],this.facetBatches=void 0,this._init()}_init(){this._data=[],this.facetBatches=new Tt([],JSON.stringify),this.facetBatches.set(void 0,this._data)}reset(){super.reset(),this._init()}handle(e){this._data.push(e)}beginBatch(e){gw(e)&&(this._data=[],this.facetBatches.set(Ke(e.facetId),this._data))}complete(){var i,o;const e=(i=this.params)==null?void 0:i.sort,n=e?yu(e.field,e.order):void 0,r=s=>{n&&s.sort(n)};if((o=this.params.groupby)!=null&&o.length){if(this.facetBatches.size>1)throw new Error("TODO: Support faceted data!");const s=this.params.groupby.map(u=>O(u)),a=hi(this._data,...s);this.facetBatches.clear();for(const[u,c]of ou(a))this.facetBatches.set(u,c)}for(const s of this.facetBatches.values())r(s);if(this.children.length)for(const[s,a]of this.facetBatches.entries()){if(s){const u={type:"facet",facetId:s};for(const c of this.children)c.beginBatch(u)}for(const u of a)this._propagate(u)}super.complete();for(const s of this.observers)s(this)}getData(){switch(this._checkStatus(),this.facetBatches.size){case 0:return[];case 1:return[...this.facetBatches.values()][0];default:{const e=this.facetBatches;return{[Symbol.iterator]:function*(){for(const r of e.values())for(let i=0;i<r.length;i++)yield r[i]}}}}}visitData(e){this._checkStatus();for(const n of this.facetBatches.values())for(let r=0;r<n.length;r++)e(n[r])}getItemCount(){let e=0;for(const n of this.facetBatches.values())e+=n.length;return e}_checkStatus(){if(!this.completed)throw new Error("Data propagation is not completed! No data are available.")}}class Do{constructor(){this.ids=[],this.values=[],this.length=0}clear(){this.length=0}push(e,n){let r=this.length++;for(;r>0;){const i=r-1>>1,o=this.values[i];if(n>=o)break;this.ids[r]=this.ids[i],this.values[r]=o,r=i}this.ids[r]=e,this.values[r]=n}pop(){if(this.length===0)return;const e=this.ids[0];if(this.length--,this.length>0){const n=this.ids[0]=this.ids[this.length],r=this.values[0]=this.values[this.length],i=this.length>>1;let o=0;for(;o<i;){let s=(o<<1)+1;const a=s+1;let u=this.ids[s],c=this.values[s];const f=this.values[a];if(a<this.length&&f<c&&(s=a,u=this.ids[a],c=f),c>=r)break;this.ids[o]=u,this.values[o]=c,o=s}this.ids[o]=n,this.values[o]=r}return e}peek(){if(this.length!==0)return this.ids[0]}peekValue(){if(this.length!==0)return this.values[0]}shrink(){this.ids.length=this.values.length=this.length}}class Yv extends q{get behavior(){return at}constructor(e){super(),this.params=e,this.startAccessor=O(e.start),this.endAccessor=O(e.end),this.chromAccessor=e.chrom?O(e.chrom):n=>{},this.weightAccessor=e.weight?O(e.weight):n=>1,this.as={coverage:e.as||"coverage",start:e.asStart||e.start,end:e.asEnd||e.end,chrom:e.asChrom||e.chrom},this.createSegment=new Function("start","end","coverage","chrom","return {"+Object.entries(this.as).filter(([n,r])=>r).map(([n,r])=>`${JSON.stringify(r)}: ${n}`).join(", ")+"};"),this.ends=new Do}reset(){super.reset(),this.initialize()}initialize(){const e=this.as.coverage,n=this.as.end,r=this.as.chrom,i=this.startAccessor,o=this.endAccessor,s=this.chromAccessor,a=this.weightAccessor;let u,c,f,l=0,h;const p=this.ends;p.clear();const d=(m,A,y)=>{if(m==A)return;let b=!1;u&&(u[e]===y?(u[n]=A,b=!0):u[e]!=0&&this._propagate(u)),b||(u=this.createSegment(m,A,y,f))},g=()=>{let m;for(;(m=p.peekValue())!==void 0;)d(h,m,l),h=m,l-=p.pop();h=void 0,u&&(this._propagate(u),u=void 0)};this.handle=m=>{const A=i(m);let y;for(;(y=p.peekValue())!==void 0&&y<A;)d(h,y,l),h=y,l-=p.pop();if(r){let C=s(m);C!==c&&(g(),f=C,c=f)}h!==void 0&&d(h,A,l),h=A;const b=a(m);l+=b,p.push(b,o(m))},this.complete=()=>{g(),super.complete()}}}function Wv(t,e,n=0,r=t.length){const i=new Do,o=r-n;let s;for(s=0;s<e&&s<o;s++)i.push(s,t[n+s]);for(;s<o;s++){const c=t[n+s];c>=i.peekValue()&&(i.push(s,c),i.pop())}const a=[];let u;for(;(u=i.pop())!==void 0;)a.push(n+u);return a.reverse()}class Xv{constructor(e,n=-1/0,r=1/0){this.maxSize=e,this.lowerLimit=n,this.upperLimit=r;const i=this.maxSize*2+1;this.lowerLimits=new Float64Array(i),this.upperLimits=new Float64Array(i),this.lowerChildren=new Int32Array(i),this.upperChildren=new Int32Array(i),this.reset()}reset(){this.lowerLimits.fill(0),this.upperLimits.fill(0),this.lowerChildren.fill(0),this.upperChildren.fill(0),this.n=1,this.lowerLimits[0]=this.lowerLimit,this.upperLimits[0]=this.upperLimit}_findSlot(e,n,r=0){if(e>=this.lowerLimits[r]&&n<=this.upperLimits[r]){const i=this.lowerChildren[r];if(i){const o=this._findSlot(e,n,i);return o>=0?o:this._findSlot(e,n,this.upperChildren[r])}else return r}else return-1}reserve(e,n){if(n-e<=0)throw new Error("Cannot reserve an empty or negative-size slot!");if(this.n+1>this.lowerLimits.length)return!1;const r=this._findSlot(e,n);if(r<0)return!1;const i=this.n++,o=this.n++;return this.lowerLimits[i]=this.lowerLimits[r],this.upperLimits[i]=e,this.lowerLimits[o]=n,this.upperLimits[o]=this.upperLimits[r],this.lowerChildren[r]=i,this.upperChildren[r]=o,!0}}class Zv extends q{constructor(e,n){if(super(),this.params=e,this._data=[],this.channel=e.channel??"x",!["x","y"].includes(this.channel))throw new Error("Invalid channel: "+this.channel);this.posAccessor=O(this.params.pos),this.posBisector=fi(this.posAccessor),this.scoreAccessor=O(this.params.score),this.widthAccessor=O(this.params.width),this.laneAccessor=this.params.lane?O(this.params.lane):i=>0,this.padding=this.params.padding??0,this.reservationMaps=new Map,this.resolution=n.getScaleResolution(this.channel);const r=()=>this._filterAndPropagate();this.schedule=()=>n.context.animator.requestTransition(r),this.resolution.addEventListener("domain",i=>this.schedule()),n._addBroadcastHandler("layoutComputed",()=>this.schedule())}complete(){const e=this.posAccessor;this._data.sort((n,r)=>e(n)-e(r)),this._scores=this._data.map(this.scoreAccessor);for(const n of new Set(this._data.map(this.laneAccessor)))this.reservationMaps.set(n,new Xv(200));this.schedule(),super.complete()}_filterAndPropagate(){var s;super.reset();const e=this.resolution.getScale(),n=(s=this.resolution.members[0].view.coords)==null?void 0:s[this.channel=="x"?"width":"height"];if(!n)return;for(const a of this.reservationMaps.values())a.reset();const r=e.domain(),i=70,o=Wv(this._scores,i,this.posBisector.left(this._data,r[0]),this.posBisector.right(this._data,r[1]));for(const a of o){const u=this._data[a],c=e(this.posAccessor(u))*n,f=this.widthAccessor(u)/2+this.padding;this.reservationMaps.get(this.laneAccessor(u)).reserve(c-f,c+f)&&this._propagate(u)}super.complete()}reset(){super.reset(),this._data=[],this.groups=new Map}handle(e){this._data.push(e)}}class Kv extends q{constructor(e){super(),this.params=e,this.predicate=void 0}initialize(){this.predicate=sa(this.params.expr,this.getGlobalObject())}handle(e){this.predicate(e)&&this._propagate(e)}}const qv="0".charCodeAt(0);function*Jv(t,e=","){const n=e.charCodeAt(0);let r=0;for(let i=0;i<t.length;i++){const o=t.charCodeAt(i);o==n?(yield r,r=0):r=r*10+o-qv}yield r}class _v extends q{get behavior(){return at}constructor(e){super();const n=O(e.exons??"exons"),r=O(e.start??"start"),[i,o]=e.as||["exonStart","exonEnd"];this.handle=s=>{let a=r(s),u=a,c=!0;const f=n(s);for(const l of Jv(f)){if(c)u=a+l;else{a=u+l;const h=Object.assign({},s);h[i]=u,h[o]=a,this._propagate(h)}c=!c}}}}class $v extends q{get behavior(){return at}constructor(e){super();const n=Ke(e.field).map(o=>O(o)),r=Ke(e.separator),i=Ke(e.as||e.field);if(n.length!==r.length||n.length!==i.length)throw new Error(`Lengths of "separator" (${r.length}), "fields" (${n.length}), and "as" (${i.length}) do not match!`);this.handle=o=>{if(n.some(u=>!u(o)))return;const s=n.map((u,c)=>u(o).split(r[c]));eC(s,o);const a=s[0].length;for(let u=0;u<a;u++){const c=Object.assign({},o);for(let f=0;f<n.length;f++)c[i[f]]=s[f][u];this._propagate(c)}}}}function eC(t,e){const n=t.map(r=>r.length);if(!n.every(r=>r==n[0]))throw new Error("Mismatching number of elements in the fields to be split: "+JSON.stringify(e))}class tC extends q{get behavior(){return Bt}constructor(e){super(),this.params=e,this.as=e.as,this.fn=void 0}initialize(){this.fn=sa(this.params.expr,this.getGlobalObject())}handle(e){e[this.as]=this.fn(e),this._propagate(e)}}class kh extends q{get behavior(){return Bt}constructor(e,n){super();const r=e.channel??"x";if(!["x","y"].includes(r))throw new Error("Invalid channel: "+r);const i=n.getScaleResolution(r).getGenome();if(!i)throw new Error("LinearizeGenomicCoordinate transform requires a locus scale!");const o=O(e.chrom),s=Ke(e.pos).map(d=>O(d)),a=Ke(e.as);if(s.length!=a.length)throw new Error('The number of "pos" and "as" elements must be equal!');const u=Ke(e.offset);let c;if(u.length==0)c=new Array(s.length).fill(0);else if(u.length==1)c=new Array(s.length).fill(u[0]);else if(u.length==s.length)c=u;else throw new Error(`Invalid "offset" parameter: ${JSON.stringify(e.offset)}!`);const f=new Function("datum","chromOffset","posAccessors",a.map((d,g)=>`datum[${JSON.stringify(d)}] = chromOffset + +posAccessors[${g}](datum) - ${c[g]};`).join(`
 `));let l,h=0;const p=d=>{if(d!==l){if(h=i.cumulativeChromPositions.get(d),h===void 0)throw new Error("Unknown chromosome/contig: "+d);l=d}return h};this.handle=d=>{f(d,p(o(d)),s),this._propagate(d)}}}const Nh={pages:["Lato-Regular.png"],chars:[{id:87,width:53,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:43.491,chnl:15,x:0,y:0,page:0},{id:124,width:17,height:50,xoffset:0,yoffset:-32.193000000000005,xadvance:10.521,chnl:15,x:0,y:42,page:0},{id:40,width:20,height:49,xoffset:0,yoffset:-32.571000000000005,xadvance:11.214,chnl:15,x:0,y:94,page:0},{id:41,width:19,height:49,xoffset:0,yoffset:-32.571000000000005,xadvance:11.214,chnl:15,x:0,y:145,page:0},{id:36,width:32,height:49,xoffset:0,yoffset:-34.419000000000004,xadvance:24.360000000000003,chnl:15,x:0,y:196,page:0},{id:125,width:21,height:48,xoffset:0,yoffset:-32.193000000000005,xadvance:12.642000000000001,chnl:15,x:0,y:247,page:0},{id:91,width:22,height:48,xoffset:0,yoffset:-32.193000000000005,xadvance:12.852,chnl:15,x:0,y:297,page:0},{id:93,width:19,height:48,xoffset:0,yoffset:-32.193000000000005,xadvance:12.852,chnl:15,x:0,y:347,page:0},{id:123,width:21,height:48,xoffset:0,yoffset:-32.193000000000005,xadvance:12.642000000000001,chnl:15,x:0,y:397,page:0},{id:106,width:19,height:48,xoffset:0,yoffset:-30.639000000000003,xadvance:10.08,chnl:15,x:0,y:447,page:0},{id:81,width:43,height:47,xoffset:0,yoffset:-30.429000000000002,xadvance:33.621,chnl:15,x:21,y:447,page:0},{id:77,width:45,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:38.997,chnl:15,x:66,y:447,page:0},{id:64,width:43,height:44,xoffset:0,yoffset:-28.539,xadvance:35.133,chnl:15,x:23,y:397,page:0},{id:92,width:28,height:43,xoffset:0,yoffset:-30.933000000000003,xadvance:18.984,chnl:15,x:68,y:397,page:0},{id:47,width:28,height:43,xoffset:0,yoffset:-30.933000000000003,xadvance:18.984,chnl:15,x:98,y:397,page:0},{id:109,width:42,height:32,xoffset:0,yoffset:-21.609,xadvance:34.545,chnl:15,x:113,y:447,page:0},{id:119,width:42,height:31,xoffset:0,yoffset:-21.315,xadvance:32.991,chnl:15,x:157,y:447,page:0},{id:42,width:25,height:42,xoffset:0,yoffset:-31.626,xadvance:17.85,chnl:15,x:128,y:397,page:0},{id:37,width:42,height:41,xoffset:0,yoffset:-30.387,xadvance:33.663000000000004,chnl:15,x:155,y:397,page:0},{id:79,width:42,height:41,xoffset:0,yoffset:-30.429000000000002,xadvance:33.621,chnl:15,x:199,y:397,page:0},{id:102,width:24,height:41,xoffset:0,yoffset:-30.534000000000002,xadvance:14.721,chnl:15,x:243,y:397,page:0},{id:100,width:31,height:41,xoffset:0,yoffset:-30.933000000000003,xadvance:23.520000000000003,chnl:15,x:269,y:397,page:0},{id:98,width:32,height:41,xoffset:0,yoffset:-30.933000000000003,xadvance:23.520000000000003,chnl:15,x:302,y:397,page:0},{id:56,width:32,height:41,xoffset:0,yoffset:-30.429000000000002,xadvance:24.360000000000003,chnl:15,x:336,y:397,page:0},{id:38,width:40,height:41,xoffset:0,yoffset:-30.429000000000002,xadvance:29.904000000000003,chnl:15,x:370,y:397,page:0},{id:108,width:17,height:41,xoffset:0,yoffset:-30.933000000000003,xadvance:9.912,chnl:15,x:412,y:397,page:0},{id:107,width:31,height:41,xoffset:0,yoffset:-30.933000000000003,xadvance:21.336000000000002,chnl:15,x:431,y:397,page:0},{id:48,width:33,height:41,xoffset:0,yoffset:-30.429000000000002,xadvance:24.360000000000003,chnl:15,x:464,y:397,page:0},{id:71,width:38,height:41,xoffset:0,yoffset:-30.429000000000002,xadvance:30.681,chnl:15,x:21,y:347,page:0},{id:83,width:31,height:41,xoffset:0,yoffset:-30.429000000000002,xadvance:22.785,chnl:15,x:61,y:347,page:0},{id:63,width:27,height:41,xoffset:0,yoffset:-30.429000000000002,xadvance:18.795,chnl:15,x:94,y:347,page:0},{id:105,width:18,height:41,xoffset:0,yoffset:-30.639000000000003,xadvance:10.08,chnl:15,x:123,y:347,page:0},{id:51,width:32,height:41,xoffset:0,yoffset:-30.429000000000002,xadvance:24.360000000000003,chnl:15,x:143,y:347,page:0},{id:104,width:31,height:41,xoffset:0,yoffset:-30.933000000000003,xadvance:23.436,chnl:15,x:177,y:347,page:0},{id:67,width:37,height:41,xoffset:0,yoffset:-30.429000000000002,xadvance:28.056,chnl:15,x:210,y:347,page:0},{id:88,width:37,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:27.258000000000003,chnl:15,x:249,y:347,page:0},{id:68,width:40,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:31.941000000000003,chnl:15,x:288,y:347,page:0},{id:70,width:32,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:23.751,chnl:15,x:330,y:347,page:0},{id:34,width:23,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:15.561000000000002,chnl:15,x:364,y:347,page:0},{id:72,width:38,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:32.067,chnl:15,x:389,y:347,page:0},{id:73,width:18,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:11.760000000000002,chnl:15,x:429,y:347,page:0},{id:74,width:24,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:17.745,chnl:15,x:449,y:347,page:0},{id:75,width:38,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:27.825000000000003,chnl:15,x:24,y:297,page:0},{id:76,width:31,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:21.567,chnl:15,x:475,y:347,page:0},{id:66,width:35,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:27.153000000000002,chnl:15,x:64,y:297,page:0},{id:78,width:38,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:32.067,chnl:15,x:101,y:297,page:0},{id:33,width:18,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:11.298,chnl:15,x:141,y:297,page:0},{id:80,width:34,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:25.221,chnl:15,x:161,y:297,page:0},{id:65,width:38,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:28.434,chnl:15,x:197,y:297,page:0},{id:82,width:36,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:26.313000000000002,chnl:15,x:237,y:297,page:0},{id:35,width:33,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:24.360000000000003,chnl:15,x:275,y:297,page:0},{id:84,width:34,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:24.801000000000002,chnl:15,x:310,y:297,page:0},{id:85,width:37,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:30.891000000000002,chnl:15,x:346,y:297,page:0},{id:86,width:38,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:28.434,chnl:15,x:385,y:297,page:0},{id:39,width:16,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:8.568000000000001,chnl:15,x:425,y:297,page:0},{id:69,width:32,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:24.255000000000003,chnl:15,x:443,y:297,page:0},{id:89,width:36,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:26.208000000000002,chnl:15,x:23,y:247,page:0},{id:90,width:34,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:25.284000000000002,chnl:15,x:477,y:297,page:0},{id:49,width:31,height:40,xoffset:0,yoffset:-30.156000000000002,xadvance:24.360000000000003,chnl:15,x:61,y:247,page:0},{id:50,width:32,height:40,xoffset:0,yoffset:-30.429000000000002,xadvance:24.360000000000003,chnl:15,x:94,y:247,page:0},{id:57,width:32,height:40,xoffset:0,yoffset:-30.429000000000002,xadvance:24.360000000000003,chnl:15,x:128,y:247,page:0},{id:94,width:32,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:24.360000000000003,chnl:15,x:162,y:247,page:0},{id:96,width:21,height:40,xoffset:0,yoffset:-30.429000000000002,xadvance:16.8,chnl:15,x:196,y:247,page:0},{id:55,width:33,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:24.360000000000003,chnl:15,x:219,y:247,page:0},{id:54,width:33,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:24.360000000000003,chnl:15,x:254,y:247,page:0},{id:53,width:32,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:24.360000000000003,chnl:15,x:289,y:247,page:0},{id:52,width:33,height:40,xoffset:0,yoffset:-30.093000000000004,xadvance:24.360000000000003,chnl:15,x:323,y:247,page:0},{id:103,width:31,height:39,xoffset:0,yoffset:-21.630000000000003,xadvance:21.84,chnl:15,x:358,y:247,page:0},{id:112,width:32,height:39,xoffset:0,yoffset:-21.651,xadvance:23.541,chnl:15,x:391,y:247,page:0},{id:113,width:31,height:39,xoffset:0,yoffset:-21.651,xadvance:23.520000000000003,chnl:15,x:425,y:247,page:0},{id:116,width:25,height:39,xoffset:0,yoffset:-28.182000000000002,xadvance:15.057,chnl:15,x:458,y:247,page:0},{id:121,width:31,height:38,xoffset:0,yoffset:-21.273,xadvance:21.651,chnl:15,x:34,y:196,page:0},{id:59,width:18,height:36,xoffset:0,yoffset:-20.706,xadvance:10.983,chnl:15,x:485,y:247,page:0},{id:43,width:32,height:34,xoffset:0,yoffset:-24.486,xadvance:24.360000000000003,chnl:15,x:67,y:196,page:0},{id:60,width:30,height:33,xoffset:0,yoffset:-23.331000000000003,xadvance:24.360000000000003,chnl:15,x:101,y:196,page:0},{id:62,width:31,height:33,xoffset:0,yoffset:-23.331000000000003,xadvance:24.360000000000003,chnl:15,x:133,y:196,page:0},{id:117,width:30,height:32,xoffset:0,yoffset:-21.273,xadvance:23.415000000000003,chnl:15,x:166,y:196,page:0},{id:99,width:29,height:32,xoffset:0,yoffset:-21.609,xadvance:20.055,chnl:15,x:198,y:196,page:0},{id:110,width:31,height:32,xoffset:0,yoffset:-21.609,xadvance:23.436,chnl:15,x:229,y:196,page:0},{id:111,width:32,height:32,xoffset:0,yoffset:-21.609,xadvance:23.814,chnl:15,x:262,y:196,page:0},{id:126,width:32,height:26,xoffset:0,yoffset:-16.128,xadvance:24.360000000000003,chnl:15,x:201,y:447,page:0},{id:101,width:31,height:32,xoffset:0,yoffset:-21.609,xadvance:22.176000000000002,chnl:15,x:296,y:196,page:0},{id:114,width:25,height:32,xoffset:0,yoffset:-21.651,xadvance:15.288,chnl:15,x:329,y:196,page:0},{id:115,width:27,height:32,xoffset:0,yoffset:-21.609,xadvance:18.186,chnl:15,x:356,y:196,page:0},{id:97,width:28,height:32,xoffset:0,yoffset:-21.651,xadvance:20.874000000000002,chnl:15,x:385,y:196,page:0},{id:118,width:31,height:31,xoffset:0,yoffset:-21.273,xadvance:21.672,chnl:15,x:415,y:196,page:0},{id:61,width:31,height:29,xoffset:0,yoffset:-19.089000000000002,xadvance:24.360000000000003,chnl:15,x:448,y:196,page:0},{id:120,width:30,height:31,xoffset:0,yoffset:-21.273,xadvance:20.916,chnl:15,x:21,y:145,page:0},{id:58,width:18,height:31,xoffset:0,yoffset:-20.706,xadvance:10.5,chnl:15,x:53,y:145,page:0},{id:122,width:28,height:31,xoffset:0,yoffset:-21.273,xadvance:18.984,chnl:15,x:73,y:145,page:0},{id:95,width:28,height:16,xoffset:0,yoffset:0,xadvance:19.278000000000002,chnl:15,x:235,y:447,page:0},{id:45,width:23,height:24,xoffset:0,yoffset:-14.175,xadvance:15.603000000000002,chnl:15,x:481,y:196,page:0},{id:44,width:17,height:21,xoffset:0,yoffset:-4.956,xadvance:9.534,chnl:15,x:103,y:145,page:0},{id:46,width:18,height:15,xoffset:0,yoffset:-4.956,xadvance:9.912,chnl:15,x:0,y:497,page:0},{id:32,width:0,height:0,xoffset:0,yoffset:0,xadvance:10.752,chnl:15,x:20,y:497,page:0}],info:{face:"Lato Regular",size:42,bold:0,italic:0,charset:[" ","!",'"',"#","$","%","&","'","(",")","*","+",",","-",".","/","0","1","2","3","4","5","6","7","8","9",":",";","<","=",">","?","@","A","B","C","D","E","F","G","H","I","J","K","L","M","N","O","P","Q","R","S","T","U","V","W","X","Y","Z","[","\\","]","^","_","`","a","b","c","d","e","f","g","h","i","j","k","l","m","n","o","p","q","r","s","t","u","v","w","x","y","z","{","|","}","~"],unicode:1,stretchH:100,smooth:1,aa:1,padding:[0,0,0,0],spacing:[2,2]},common:{lineHeight:50.400000000000006,base:41.454,scaleW:512,scaleH:512,pages:1,packed:0,alphaChnl:0,redChnl:0,greenChnl:0,blueChnl:0},kernings:[]};class nC extends q{get behavior(){return Bt}constructor(e){super();const n=Va(Nh),r=O(e.field),i=e.as,o=e.fontSize;this.handle=s=>{const a=r(s);a!==void 0?s[i]=n.measureWidth(a,o):s[i]=0,this._propagate(s)}}}const rC=65536;class iC extends q{get behavior(){return Bt}constructor(e){super(),this.params=e}reset(){this.initialize()}initialize(){const e=this.params,n=e.as||"lane",r=me(e.spacing)?e.spacing:1,i=O(e.start),o=O(e.end);if(!e.preference!=!e.preferredOrder)throw new Error('Must specify both "preference" and "preferredOrder"');if(e.preference){const s=new Float64Array(rC),a=O(e.preference),u=e.preferredOrder;let c=1/0;this.handle=f=>{const l=i(f);l<c&&s.fill(-1/0),c=l;const h=u.indexOf(a(f));let p=-1;if(h>=0&&s[h]<l)p=h;else{const d=i(f);for(p=0;p<s.length&&!(s[p]<d);p++);if(p>=s.length)throw new Error("Out of lanes!")}s[p]=o(f)+r,f[n]=p,this._propagate(f)}}else{const s=new Do,a=new Do;let u=-1/0,c=0;this.handle=f=>{const l=i(f);for(;s.length&&(s.peekValue()<=l||l<u);){const p=s.pop();a.push(p,p)}u=l;let h=a.pop();h===void 0&&(h=c++),f[n]=h,this._propagate(f),s.push(h,o(f)+r)}}}}class oC extends q{get behavior(){return at}constructor(e){if(super(),e.as&&e.as.length!=e.fields.length)throw new Error('"fields" and "as" have unequal lengths!');const n=e.fields.map(i=>O(i)),r=e.as?e.as:n.map(Z);this.handle=i=>{const o={};for(let s=0;s<n.length;s++)o[r[s]]=n[s](i);this._propagate(o)}}}class sC extends q{get behavior(){return Bt}constructor(e){super();const n=new RegExp(e.regex),r=typeof e.as=="string"?[e.as]:e.as,i=O(e.field);this.handle=o=>{const s=i(o);if(W(s)){const a=s.match(n);if(a){if(a.length-1!=r.length)throw new Error('The number of RegEx groups and the length of "as" do not match!');for(let u=0;u<r.length;u++)o[r[u]]=a[u+1]}else if(e.skipInvalidInput)for(let u=0;u<r.length;u++)o[r[u]]=void 0;else throw new Error(`"${s}" does not match the given regex: ${n.toString()}`)}else if(!e.skipInvalidInput)throw new Error(`Trying to match a non-string field. Encountered type: ${typeof s}, field content: "${s}".`);this._propagate(o)}}}class aC extends q{get behavior(){return at}constructor(e){super();const n=Ke(e.columnRegex).map(h=>new RegExp(h)),r=Ke(e.asValue);if(n.length!=r.length)throw new Error('Lengths of "columnRegex" and "as" are not equal!');const i=e.skipRegex?new RegExp(e.skipRegex):void 0,o=e.asKey||"sample";let s,a,u;const c=h=>{var m;const p=Object.keys(h),d=new Map;for(const[A,y]of n.entries())for(const b of p){const C=(m=y.exec(b))==null?void 0:m[1];if(C!==void 0){let B=d.get(C);B||(B=[],d.set(C,B)),B[A]=b}}s=[...d.entries()],a=p.filter(A=>!n.some(y=>y.test(A))&&!(i&&i.test(A)));const g=[...a.map(A=>JSON.stringify(A)+": datum["+JSON.stringify(A)+"]"),JSON.stringify(o)+": sampleId",...r.map(A=>JSON.stringify(A)+": null")];u=new Function("datum","sampleId",`return {
 `+g.join(`,
 `)+`
@@ -152,4 +152,4 @@ if(scale<1.0){if(uSqueeze){vec2 scaleFadeExtent=vec2(3.0,6.0)/size;if(scale<scal
 `)+" };");return n.properties=e,n}class Uh extends q{get behavior(){return at}constructor(){super();const e=n=>{const r=CC(n);this.handle=i=>this._propagate(r(i)),this.handle(n)};this.handle=e,this.beginBatch=n=>{_0(n)&&(this.handle=e),super.beginBatch(n)}}}function EC(t){return"name"in t}class Hh extends On{constructor(n,r){super();he(this,ti,void 0);this.provider=r,this.params=n}get identifier(){return this.params.name}updateDynamicData(n){Yn(this,ti,n),this.loadSynchronously()}loadSynchronously(){const n=Q(this,ti)??this.provider(this.params.name)??[];let r=i=>i;if(Array.isArray(n))n.length>0&&(r=So(n[0]));else throw new Error(`Named data "${this.params.name}" is not an array!`);this.reset(),this.beginBatch({type:"file"});for(const i of n)this._propagate(r(i));this.complete()}async load(){this.loadSynchronously()}}ti=new WeakMap;class Qh{constructor(){this._dataSourcesByHost=new Map,this._collectorsByHost=new Map,this._observers=new Map}get dataSources(){return[...new Set(this._dataSourcesByHost.values()).values()]}get collectors(){return[...this._collectorsByHost.values()]}addObserver(e,n){let r=this._observers.get(n);r||(r=[],this._observers.set(n,r)),r.push(e)}_relayObserverCallback(e,n){const r=this._observers.get(n);if(r)for(const i of r)i(e)}addDataSource(e,n){this._dataSourcesByHost.set(n,e)}findDataSourceByKey(e){return this._dataSourcesByHost.get(e)}findNamedDataSource(e){let n,r=[];for(const[i,o]of this._dataSourcesByHost.entries())if(o instanceof Hh&&e==o.identifier){if(n&&n!==o)throw new Error(`Found multiple instances of named data: ${e}. Data flow optimization is broken (it's a bug).`);n=o,r.push(i)}if(n)return{dataSource:n,hosts:r}}addCollector(e,n){this._collectorsByHost.set(n,e),e.observers.push(r=>this._relayObserverCallback(r,n))}findCollectorByKey(e){return this._collectorsByHost.get(e)}initialize(){for(const e of this.dataSources)e.visit(n=>n.initialize())}}function SC(t,e){const n=[];let r;const i=e??new Qh,o=[];function s(f,l=()=>{}){if(!r)throw l()||new Error("Cannot append data flow node, no parent exist!");return r.addChild(f),r=f,f}function a(f,l){return s(f,()=>new Error(`Cannot append a transform because no (inherited) data are available! ${l?JSON.stringify(l):""}`))}function u(f,l){for(const h of f){let p;try{p=dC(h,l)}catch(d){throw console.warn(d),new Error(`Cannot initialize "${h.type}" transform: ${d}`)}p.behavior&Bt&&a(new Uh),a(p)}}const c=f=>{if(n.push(r),f.spec.data){const l=Dv(f.spec.data)?f.getDynamicDataSource():EC(f.spec.data)?new Hh(f.spec.data,f.context.getNamedDataFromProvider):vC(f.spec.data,f.getBaseUrl());r=l,i.addDataSource(l,f)}if(f.spec.transform&&u(f.spec.transform,f),f instanceof we){if(!r)throw new Error("A unit view has no (inherited) data source");const l=DC(f);if(l){o.push(l.rewrite);for(const p of l.transforms)a(p)}f.mark.isPickingParticipant()&&a(new Gh({type:"identifier"}));const h=new su({type:"collect",groupby:f.getFacetFields(),sort:BC(f,l==null?void 0:l.rewrittenEncoding)});s(h),i.addCollector(h,f)}Lh(f.spec)};return c.postOrder=f=>{r=n.pop()},t.visit(c),o.forEach(f=>f()),i}function DC(t){var o;const e=[],n={},r=[];for(const[s,a]of Object.entries(t.getEncoding())){const u=s;kr(u)&&xf(a)&&r.push({channel:u,chromPosDef:a})}const i=hi(r,s=>Cn(s.channel),s=>s.chromPosDef.chrom);for(const[s,a]of i.entries())for(const[u,c]of a.entries()){const f=[],l=[],h=[];for(const{channel:p,chromPosDef:d}of c){const g=y=>y.replace(/[^A-Za-z0-9_]/g,""),m=["_linearized_",g(d.chrom),"_",g(d.pos)].join(""),A={...((o=t.spec.encoding)==null?void 0:o[p])??t.getEncoding()[p]??{},field:m};delete A.chrom,delete A.pos,!A.type&&d.type&&(A.type=d.type),n[p]=A,f.push(d.pos),h.push(d.offset??0),l.push(m)}e.push(new kh({type:"linearizeGenomicCoordinate",channel:s,chrom:u,pos:f,offset:h,as:l},t))}return e.length?{transforms:e,rewrittenEncoding:n,rewrite:()=>{t.spec.encoding={...t.spec.encoding,...n},V0(t.mark,"encoding")}}:void 0}function BC(t,e){var r;const n={...t.getEncoding(),...e}.x;if(Pe(n)&&(r=t.getScaleResolution("x"))!=null&&r.isZoomable()){if(Pr(n))return{field:n.field};if(!Rr(n))throw new Error("A zoomable x channel must be mapped to a field.")}}function jh(t,e=void 0){if(t.parent!==e)return!1;for(const n of t.children)if(!jh(n,t))return!1;return!0}function au(t,e=!1){if(t instanceof su&&(e=!0),t instanceof Uh)if(e)e=!1;else{const n=t.children[0];t.excise(),n&&au(n,e);return}t.behavior&at&&(e=!1);for(let n=0,r=t.children.length;n<r;n++)au(t.children[n],e||n<r-1)}function FC(t){const e=[...t._dataSourcesByHost.entries()],n=new Map;for(const r of e){const i=r[1];i.identifier&&!n.has(i.identifier)&&n.set(i.identifier,i)}t._dataSourcesByHost.clear();for(let[r,i]of e){const o=n.get(i.identifier);o&&(o.adoptChildrenOf(i),i=o),t.addDataSource(i,r)}}function MC(t){if(au(t),!jh(t))throw new Error("Encountered a bug! There's a problem in the data flow structure.")}function IC(t){for(const e of t.dataSources)MC(e);FC(t)}function TC(t){t.visit(n=>{n instanceof we&&n.resolve("scale")});const e=new Set;t.visit(n=>{for(const r of Object.values(n.resolutions.scale)){const i=r.name;if(i&&e.has(i))throw new Error(`The same scale name "${i}" occurs in multiple scale resolutions!`);e.add(i)}}),t.visit(n=>{n instanceof we&&n.resolve("axis")}),t.visit(n=>n.onScalesResolved())}function PC(t){for(const e of Lr){const n=t.getScaleResolution(e);n&&!n.name&&n.isZoomable()&&(n.name=`${e}_at_root`)}}async function RC(t,e,n){var s;if(!t.import.url)throw new Error("Cannot import, not an import spec: "+JSON.stringify(t));const r=Si({baseURL:e}),i=t.import.url,o=JSON.parse(await r.load(i).catch(a=>{throw new Error(`Could not load imported view spec: ${i} 
 Reason: ${a.message}`)}));if(n.isViewSpec(o))return o.baseUrl=(s=i.match(/^[^?#]*\//))==null?void 0:s[0],o;throw new Error(`The imported spec "${i}" is not a view spec: ${JSON.stringify(t)}`)}async function Vh(t){const e=[];t.visit(n=>{if(n instanceof Ch)return e.push(n),nh});for(const n of e){const r=n.context,i=await RC(n.spec,n.getBaseUrl(),r),o=r.createView(i,n.parent,n.name);n.parent.replaceChild(n,o),await Vh(o)}}class Yh{constructor(e){this.globalOptions=e}pushView(e,n){}popView(e){}renderMark(e,n){}}class Wh extends Yh{constructor(e,n){super(e),this.webGLHelper=n,this.buffer=[],this.coords=void 0,this.views=new Set}pushView(e,n){this.views.add(e),this.coords=n}renderMark(e,n){if(this.globalOptions.picking&&!e.isPickingParticipant())return;const r=e.render(n);r&&this.buffer.push({mark:e,callback:r,coords:this.coords,clipRect:n.clipRect})}renderDeferred(){if(this.batch||this._buildBatch(),this.batch.length==0)return;const e=this.webGLHelper.gl,n=this.globalOptions.picking;e.bindFramebuffer(e.FRAMEBUFFER,n?this.webGLHelper._pickingBufferInfo.framebuffer:null),this.webGLHelper.clearAll();for(const r of this.views)r.onBeforeRender();for(const r of this.batch)r();n&&e.bindFramebuffer(e.FRAMEBUFFER,null)}_buildBatch(){this.batch=[];let e=!0,n=!0;const r=s=>()=>{e&&s()},i=s=>()=>{e&&n&&s()},o=hi(this.buffer,s=>s.mark);for(const[s,a]of o.entries()){if(!s.isReady())continue;this.batch.push(()=>{e=s.unitView.getEffectiveOpacity()>0}),this.batch.push(...s.prepareRender(this.globalOptions).map(c=>r(c)));let u;for(const c of a){const f=c.coords;f.equals(u)||this.batch.push(r(()=>{n=s.setViewport(f,c.clipRect)})),this.batch.push(i(c.callback)),u=c.coords}}}}class LC extends Yh{constructor(...e){super({}),this.contexts=e}pushView(e,n){for(const r of this.contexts)r.pushView(e,n)}popView(e){for(const n of this.contexts)n.popView(e)}renderMark(e,n){for(const r of this.contexts)r.renderMark(e,n)}}class kC{constructor(e,n){this.point=e,this.uiEvent=n,this.stopped=!1,this.target=void 0}stopPropagation(){this.stopped=!0}get type(){return this.uiEvent.type}}class NC{constructor(e,n){this.x=e,this.y=n}equals(e){return e?e===this||e.x===this.x&&e.y===this.y:!1}}const zC=t=>new Promise(e=>setTimeout(e,t));function OC(t){const e=t.requestAnimationFrame||window.requestAnimationFrame,n=t.signal,r=()=>new Promise((i,o)=>{if(n!=null&&n.aborted)return o("aborted");const s=performance.now(),a=s+(t.duration||1e3),u=typeof t.from=="number"?t.from:0,c=typeof t.to=="number"?t.to:1,f=t.easingFunction||(g=>g),l=g=>(g-s)/(a-s),h=g=>g*(c-u)+u,p=g=>Math.max(0,Math.min(1,g)),d=g=>{n!=null&&n.aborted?o("aborted"):(t.onUpdate(h(f(p(l(g))))),g<a?e(d):(t.onUpdate(h(f(1))),i()))};e(d)});return t.delay?n!=null&&n.aborted?Promise.reject("aborted"):zC(t.delay).then(r):r()}class GC{constructor(e){this._renderCallback=e,this._renderRequested=!1,this._warn=!1,this.transitions=[]}requestTransition(e){this.cancelTransition(e),this.transitions.push(e),this.requestRender()}cancelTransition(e){const n=this.transitions.indexOf(e);n>=0&&this.transitions.splice(n,1)}requestRender(){this._renderRequested?this._warn&&console.warn("Render already requested!"):(this._renderRequested=!0,window.requestAnimationFrame(e=>{this._renderRequested=!1;const n=this.transitions;this.transitions=[];let r;for(;r=n.shift();)r(e);this._renderCallback(e)}))}transition(e){return OC({requestAnimationFrame:n=>this.requestTransition(n),...e})}}function Xh(){const t=e=>e;return t.invert=e=>e,t.copy=Xh,t.invertRange=()=>{},t}class UC{constructor(e){this.genomes=new Map,this.genomeSpy=e}async initialize(e){const n=new cv(e);return this.genomes.set(n.name,n),Promise.all([...this.genomes.values()].map(r=>r.load(this.genomeSpy.spec.baseUrl)))}getGenome(e){if(!this.genomes.size)throw new Error("No genomes have been configured!");if(e){const n=this.genomes.get(e);if(!n)throw new Error(`No genome with the name ${e} has been configured!`);return n}else{if(this.genomes.size>1)throw new Error("Cannot pick a default genome! More than one have been configured!");return this.genomes.values().next().value}}}const HC="data:image/png;base64,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",QC={thin:100,light:300,regular:400,normal:400,medium:500,bold:700,black:900};class jC{constructor(e){this._webGLHelper=e,this.fontRepository="https://raw.githubusercontent.com/etiennepinchon/aframe-fonts/master/fonts/",this._fonts=new Tt([],JSON.stringify),this._metadataPromises=new Map,this._fontPromises=new Map,this._promises=[],this._defaultFontEntry={metrics:Va(Nh),texture:this._createTextureNow(HC)}}async waitUntilReady(){await Promise.all(this._promises)}getFont(e,n="normal",r="regular"){if(W(r)&&(r=QC[r.toLowerCase()],!r))throw new Error("Unknown font weight: "+r);const i={family:e,style:n,weight:r};let o=this._fonts.get(i);return o||(o={metrics:void 0,texture:void 0},this._fonts.set(i,o),this._promises.push(this._loadFontEntry(o,i))),o}async _loadFontEntry(e,n){try{const r=await this._loadMetadata(n.family),i=YC(r,n),o=this.fontRepository+Zh(n.family)+"/"+i.replace(/\.\w+/,""),s=this._createTexture(o+".png"),a=this._loadFont(o+".json");e.texture=await s,e.metrics=await a}catch(r){console.log("Cannot load font. Using default.",r),e.metrics=this._defaultFontEntry.metrics,e.texture=this._defaultFontEntry.texture}}_loadFont(e){let n=this._fontPromises.get(e);return n||(n=fetch(e).then(r=>{if(!r.ok)throw new Error("Could not load font: "+r.status);return r}).then(r=>r.json()).then(r=>Va(r)),this._fontPromises.set(e,n)),n}_loadMetadata(e){const n=Zh(e);let r=this._metadataPromises.get(n);return r||(r=fetch(this.fontRepository+n+"/METADATA.pb").then(i=>{if(!i.ok)throw new Error("Could not load font metadata: "+i.status);return i}).then(i=>i.text()).then(i=>VC(i)).catch(i=>{console.warn(i)}),this._metadataPromises.set(n,r)),r}getDefaultFont(){return this._defaultFontEntry}_createTexture(e){const n=this._webGLHelper.gl;return new Promise((r,i)=>{Qr(n,{src:e,min:n.LINEAR},(o,s,a)=>{o?i(o):r(s)})})}_createTextureNow(e){const n=this._webGLHelper.gl;let r;const i=new Promise((o,s)=>{r=Qr(n,{src:e,min:n.LINEAR},(a,u,c)=>{a?s(a):o(u)})});return this._promises.push(i),r}}function Zh(t){return t.toLowerCase().replaceAll(/[^\w]/g,"")}function VC(t){const e=t.split(`
 `),n=[];let r;for(const i of e)if(i.startsWith("fonts {")&&(r={name:void 0,style:void 0,weight:void 0,filename:void 0,post_script_name:void 0,full_name:void 0,copyright:void 0}),i.startsWith("}")&&(n.push(r),r=void 0),r){let o=i.match(/^\s*([A-Za-z_]+):[ ]?"(.*)"$/);if(o){const s=o[1];r[s]=o[2]}if(o=i.match(/^\s*([A-Za-z_]+):[ ]?(\d+)$/),o){const s=o[1];r[s]=+o[2]}}return n}function YC(t,e){let n,r=Number.POSITIVE_INFINITY;for(const i of t)if(e.family.localeCompare(i.name,void 0,{sensitivity:"accent"})==0&&e.style==i.style){const o=Math.abs(e.weight-i.weight);o<r&&(r=o,n=i)}return n==null?void 0:n.filename}function WC(t,e){const n=[];let r;for(const i of t.split(`
-`))if(i.startsWith(">"))r={identifier:i.match(/>(\S+)/)[1],sequence:""},n.push(r);else if(r)r.sequence+=i.trim();else throw new Error("Invalid fasta file!");return n}class XC{constructor(e,n){this.animator=e,this.disabled=!!n,this.damping=.015,this.acceleration=.3,this.accelerationThreshold=100,this.lowerLimit=.5,this.loop=!1,this.momentum=0,this.timestamp=0,this.callback=null,this._transitionCallback=this.animate.bind(this),this.clear()}clear(){this.momentum=0,this.timestamp=null,this.loop=null,this.callback=null}cancel(){this.loop&&(this.animator.cancelTransition(this._transitionCallback),this.clear())}setMomentum(e,n){if(this.disabled){n(e);return}e*this.momentum<0?this.momentum=0:Math.abs(e)>this.accelerationThreshold?this.momentum=Cd([this.momentum,e],this.acceleration):this.momentum=e,this.callback=n,this.loop||this.animate()}animate(e){this.callback(this.momentum);const n=e-this.timestamp||0;this.timestamp=e;const r=Math.abs(this.momentum);this.momentum=Math.sign(this.momentum)*Math.max(0,r-((r*this.damping)**1.5+.04)*n),Math.abs(this.momentum)>this.lowerLimit?(this.loop=!0,this.animator.requestTransition(this._transitionCallback)):this.clear()}}function ZC(t){const e={},n=["string","number","boolean"],r=["wheelDelta","wheelDeltaX","wheelDeltaY"];for(const i in t){const o=i;!r.includes(i)&&n.includes(typeof t[o])&&(e[o]=t[o])}return e}function KC(t,e,n=!0){let r,i=s=>{};return function(...a){return new Promise((u,c)=>{const f=()=>{clearTimeout(r),i=l=>{},u(t(...a))};n&&i("debounced"),clearTimeout(r),i=c,r=setTimeout(f,e)})}}const Kh=new Map;async function qC(t,e,n){const r=t.symbol;let i=Kh.get(r)??await $C(t.symbol);return i?(Kh.set(r,i),nt`<div class="title"><strong>${i.name}</strong> ${i.description}</div><p class="summary">${i.summary}</p><p class="source">Source: NCBI RefSeq Gene</p>`):null}async function JC(t){console.log("Searching: "+t);const e={mode:"cors"},r=(await fetch(`https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=gene&term=${t}[GENE]&sort=relevance&retmode=json`,e).then(i=>i.json())).esearchresult.idlist[0];return r?(await fetch(`https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=gene&id=${r}&retmode=json`,e).then(s=>s.json())).result[r]:null}const _C=KC(JC,500);function $C(t){return _C(t)}const eE=oe(".4~r"),tE=oe(".4~e");function nE(t){return t===null?nt`<span class="na">NA</span>`:W(t)?t.substring(0,30):Number.isInteger(t)?""+t:me(t)?Math.abs(t)>Math.pow(10,8)||Math.abs(t)<Math.pow(10,-8)?tE(t):eE(t):ai(t)?t?"True":"False":"?"+typeof t+" "+t}async function rE(t,e,n){const r=(a,u)=>{var c;for(const[f,l]of Object.entries(e.encoders))if((c=l==null?void 0:l.accessor)!=null&&c.fields.includes(a))switch(f){case"color":case"fill":case"stroke":return nt`<span class="color-legend" style="${`background-color: ${l(u)}`}"></span>`}return""},i=nt`<table class="attributes">${Object.entries(t).filter(([a,u])=>!a.startsWith("_")).map(([a,u])=>nt`<tr><th>${a}</th><td>${nE(u)} ${r(a,t)}</td></tr>`)}</table>`,o=e.unitView.getTitleText(),s=o?nt`<div class="title"><strong>${o}</strong></div>`:"";return nt`${s}${i}`}class iE extends Rh{constructor(e,n){super({vconcat:[]},e,void 0,"implicitRoot",1),n.parent=this,this.appendChild(n)}}N("index",ds,["continuous"]),N("locus",nm,["continuous"]),N("null",Xh,[]),Cc("fasta",WC);class qh{constructor(e,n,r={}){this.container=e,this.spec=n,this.accessorFactory=new j1,this.viewFactory=new Hv,this.namedDataProviders=[],this.animator=new GC(()=>this.renderAll()),this.genomeStore=void 0,this.viewVisibilityPredicate=i=>i.isVisibleInSpec(),this._renderingContext=void 0,this._pickingContext=void 0,this._dirtyPickingBuffer=!1,this._currentHover=void 0,this._wheelInertia=new XC(this.animator),this._keyboardListeners=new Map,this._eventListeners=new Map,this.tooltipHandlers={default:rE,refseqgene:qC,...r.tooltipHandlers??{}},this.viewRoot=void 0}registerNamedDataProvider(e){this.namedDataProviders.unshift(e)}getNamedDataFromProvider(e){for(const n of this.namedDataProviders){const r=n(e);if(r)return r}}updateNamedData(e,n){const r=this.viewRoot.context.dataFlow.findNamedDataSource(e);if(!r)throw new Error("No such named data source: "+e);r.dataSource.updateDynamicData(n);for(const i of r.hosts)i.visit(o=>{for(const s of Object.values(o.resolutions.scale))s.reconfigure()});this.animator.requestRender()}broadcast(e,n){const r={type:e,payload:n};this.viewRoot.visit(i=>i.handleBroadcast(r))}_prepareContainer(){this.container.classList.add("genome-spy"),this.container.classList.add("loading"),this._glHelper=new iw(this.container,()=>{if(this.viewRoot){const e=this.viewRoot.getSize().addPadding(this.viewRoot.getOverhang()),n=r=>r.grow>0?void 0:r.px;return{width:n(e.width),height:n(e.height)}}}),this.loadingMessageElement=document.createElement("div"),this.loadingMessageElement.className="loading-message",this.loadingMessageElement.innerHTML='<div class="message">Loading<span class="ellipsis">...</span></div>',this.container.appendChild(this.loadingMessageElement),this.tooltip=new vA(this.container),this.loadingMessageElement.querySelector(".message").addEventListener("transitionend",()=>{this.loadingMessageElement.style.display="none"})}destroy(){this.container.classList.remove("genome-spy"),this.container.classList.remove("loading");for(const[e,n]of this._keyboardListeners)for(const r of n)document.removeEventListener(e,r);for(this._glHelper.finalize();this.container.firstChild;)this.container.firstChild.remove()}async _prepareViewsAndData(){this.spec.genome&&(this.genomeStore=new UC(this),await this.genomeStore.initialize(this.spec.genome));const e=this,n={dataFlow:new Qh,accessorFactory:this.accessorFactory,glHelper:this._glHelper,animator:this.animator,genomeStore:this.genomeStore,fontManager:new jC(this._glHelper),requestLayoutReflow:()=>{},updateTooltip:this.updateTooltip.bind(this),getNamedDataFromProvider:this.getNamedDataFromProvider.bind(this),getCurrentHover:()=>this._currentHover,addKeyboardListener:(a,u)=>{document.addEventListener(a,u);let c=this._keyboardListeners.get(a);c||(c=[],this._keyboardListeners.set(a,c)),c.push(u)},isViewVisible:e.viewVisibilityPredicate,isViewSpec:a=>e.viewFactory.isViewSpec(a),createView:function(a,u,c){return e.viewFactory.createView(a,n,u,c)}},r=this.spec;r.datasets&&this.registerNamedDataProvider(a=>r.datasets[a]),this.viewRoot=n.createView(r,null,"viewRoot"),await Vh(this.viewRoot),(this.viewRoot instanceof we||this.viewRoot instanceof tn)&&(this.viewRoot=new iE(n,this.viewRoot)),TC(this.viewRoot),PC(this.viewRoot),this._glHelper.invalidateSize();const i=[];this.viewRoot.visit(a=>{a instanceof we&&i.push(a)});const o=SC(this.viewRoot,n.dataFlow);IC(o),this.broadcast("dataFlowBuilt",o),o.dataSources.forEach(a=>console.log(a.subtreeToString())),i.forEach(a=>a.mark.initializeEncoders());const s=Promise.all(i.map(a=>a.mark.initializeGraphics()));for(const a of i)o.addObserver(u=>{a.mark.initializeData(),a.mark.updateGraphicsData()},a);await n.fontManager.waitUntilReady(),o.initialize(),await Promise.all(o.dataSources.map(a=>a.load())),this.viewRoot.visit(a=>{for(const u of Object.values(a.resolutions.scale))u.reconfigure()}),this.broadcast("dataLoaded"),await s,this.viewRoot.visit(a=>{for(const u of Object.values(a.resolutions.scale))this._glHelper.createRangeTexture(u)});for(const a of i)a.mark.finalizeGraphicsInitialization();n.requestLayoutReflow=this.computeLayout.bind(this),this.viewRoot.visit(a=>wo(a,"size")),this._glHelper.invalidateSize()}async launch(){try{return this._prepareContainer(),await this._prepareViewsAndData(),this.registerMouseEvents(),this.computeLayout(),this.animator.requestRender(),this._glHelper.addEventListener("resize",()=>{this.computeLayout(),this.renderAll()}),!0}catch(e){const n=`${e.view?`At "${e.view.getPathString()}": `:""}${e.toString()}`;return console.error(e.stack),oE(this.container,n),!1}finally{this.container.classList.remove("loading"),window.setTimeout(()=>{this.loadingMessageElement.style.display="none"},2e3)}}registerMouseEvents(){const e=this._glHelper.canvas,n=r=>{var i;if(r instanceof MouseEvent){r.type=="mousemove"&&(this.tooltip.handleMouseMove(r),this._tooltipUpdateRequested=!1,r.buttons==0&&this.renderPickingFramebuffer());const o=e.getBoundingClientRect(),s=new NC(r.clientX-o.left-e.clientLeft,r.clientY-o.top-e.clientTop),a=u=>{this.viewRoot.propagateInteractionEvent(new kC(s,u)),this._tooltipUpdateRequested||this.tooltip.clear()};if(r.type!="wheel"&&this._wheelInertia.cancel(),r.type=="mousemove")this._handlePicking(s.x,s.y);else if(r.type=="mousedown"||r.type=="mouseup")this.renderPickingFramebuffer();else if(r.type=="wheel"){this._tooltipUpdateRequested=!1;const u=r;if(Math.abs(u.deltaX)>Math.abs(u.deltaY))this._currentHover=null,this._wheelInertia.cancel();else{const c=ZC(u);this._wheelInertia.setMomentum(u.deltaY*(u.deltaMode?80:1),f=>{const l=new WheelEvent("wheel",{...c,deltaMode:0,deltaX:0,deltaY:f});a(l)}),u.preventDefault();return}}if(r.type=="click"){const u=this._currentHover?{type:r.type,viewPath:[...this._currentHover.mark.unitView.getAncestors()].map(c=>c.name).reverse(),datum:this._currentHover.datum}:{type:r.type,viewPath:null,datum:null};(i=this._eventListeners.get("click"))==null||i.forEach(c=>c(u))}a(r)}};["mousedown","mouseup","wheel","click","mousemove","gesturechange","contextmenu"].forEach(r=>e.addEventListener(r,n)),e.addEventListener("mousedown",()=>{document.addEventListener("mouseup",()=>this.tooltip.popEnabledState(),{once:!0}),this.tooltip.pushEnabledState(!1)}),e.addEventListener("dragstart",r=>r.stopPropagation())}_handlePicking(e,n){var o;const r=this._glHelper.readPickingPixel(e,n),i=r[0]|r[1]<<8|r[2]<<16;if(i==0){this._currentHover=null;return}if(i!==((o=this._currentHover)==null?void 0:o.uniqueId)&&(this._currentHover=null),this._currentHover||this.viewRoot.visit(s=>{if(s instanceof we){if(s.mark.isPickingParticipant()){const a=s.mark.encoders.uniqueId.accessor;s.getCollector().visitData(u=>{a(u)==i&&(this._currentHover={mark:s.mark,datum:u,uniqueId:i})})}if(this._currentHover)return Zr}}),this._currentHover){const s=this._currentHover.mark;this.updateTooltip(this._currentHover.datum,async a=>{if(!s.isPickingParticipant())return;const u=s.properties.tooltip;if(u!==null){const c=(u==null?void 0:u.handler)??"default",f=this.tooltipHandlers[c];if(!f)throw new Error("No such tooltip handler: "+c);return f(a,s,u==null?void 0:u.params)}})}}updateTooltip(e,n){if(!this._tooltipUpdateRequested||!e)this.tooltip.updateWithDatum(e,n),this._tooltipUpdateRequested=!0;else throw new Error("Tooltip has already been updated! Duplicate event handler?")}computeLayout(){const e=this.viewRoot;if(!e)return;this.broadcast("layout");const n=this._glHelper.getLogicalCanvasSize();if(isNaN(n.width)||isNaN(n.height)){console.log(`NaN in canvas size: ${n.width}x${n.height}. Skipping computeLayout().`);return}this._renderingContext=new Wh({picking:!1},this._glHelper),this._pickingContext=new Wh({picking:!0},this._glHelper),e.render(new LC(this._renderingContext,this._pickingContext),zn.create(0,0,n.width,n.height)),this.broadcast("layoutComputed")}renderAll(){var e;(e=this._renderingContext)==null||e.renderDeferred(),this._dirtyPickingBuffer=!0}renderPickingFramebuffer(){this._dirtyPickingBuffer&&(this._pickingContext.renderDeferred(),this._dirtyPickingBuffer=!1)}getSearchableViews(){const e=[];return this.viewRoot.visit(n=>{n instanceof we&&n.getAccessor("search")&&e.push(n)}),e}getNamedScaleResolutions(){const e=new Map;return this.viewRoot.visit(n=>{for(const r of Object.values(n.resolutions.scale))r.name&&e.set(r.name,r)}),e}}function oE(t,e){const n=document.createElement("div");n.className="message-box";const r=document.createElement("div");r.textContent=e,n.appendChild(r),t.appendChild(n)}const sE="data:image/svg+xml;base64,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";async function aE(t,e,n={}){let r;if(W(t)){if(r=document.querySelector(t),!r)throw new Error(`No such element: ${t}`)}else if(t instanceof HTMLElement)r=t;else throw new Error(`Invalid element: ${t}`);let i;try{const o=Le(e)?e:await Jh(e);if(o.baseUrl??(o.baseUrl=""),o.width??(o.width="container"),o.padding??(o.padding=10),r==document.body){const s=document.createElement("div");s.style.position="fixed",s.style.inset="0",s.style.overflow="hidden",r.appendChild(s),r=s}i=new qh(r,o,n),uE(i,n),await i.launch()}catch(o){r.innerText=o.toString(),console.error(o)}return{finalize(){for(i.destroy();r.firstChild;)r.firstChild.remove()},addEventListener(o,s){const a=i._eventListeners;let u=a.get(o);u||(u=new Set,a.set(o,u)),u.add(s)},removeEventListener(o,s){var u;(u=i._eventListeners.get(o))==null||u.delete(s)},getScaleResolutionByName(o){return i.getNamedScaleResolutions().get(o)},updateNamedData:i.updateNamedData.bind(i)}}function uE(t,e){e.namedDataProvider&&t.registerNamedDataProvider(e.namedDataProvider)}async function Jh(t){let e;try{e=JSON.parse(await Si().load(t))}catch(n){throw new Error(`Could not load or parse configuration: ${t}, reason: ${n.message}`)}if(!e.baseUrl){const n=t.match(/^[^?#]*\//);e.baseUrl=n&&n[0]||"./"}return e}P.GenomeSpy=qh,P.embed=aE,P.html=nt,P.icon=sE,P.loadSpec=Jh,Object.defineProperty(P,Symbol.toStringTag,{value:"Module"})});
+`))if(i.startsWith(">"))r={identifier:i.match(/>(\S+)/)[1],sequence:""},n.push(r);else if(r)r.sequence+=i.trim();else throw new Error("Invalid fasta file!");return n}class XC{constructor(e,n){this.animator=e,this.disabled=!!n,this.damping=.015,this.acceleration=.3,this.accelerationThreshold=100,this.lowerLimit=.5,this.loop=!1,this.momentum=0,this.timestamp=0,this.callback=null,this._transitionCallback=this.animate.bind(this),this.clear()}clear(){this.momentum=0,this.timestamp=null,this.loop=null,this.callback=null}cancel(){this.loop&&(this.animator.cancelTransition(this._transitionCallback),this.clear())}setMomentum(e,n){if(this.disabled){n(e);return}e*this.momentum<0?this.momentum=0:Math.abs(e)>this.accelerationThreshold?this.momentum=Cd([this.momentum,e],this.acceleration):this.momentum=e,this.callback=n,this.loop||this.animate()}animate(e){this.callback(this.momentum);const n=e-this.timestamp||0;this.timestamp=e;const r=Math.abs(this.momentum);this.momentum=Math.sign(this.momentum)*Math.max(0,r-((r*this.damping)**1.5+.04)*n),Math.abs(this.momentum)>this.lowerLimit?(this.loop=!0,this.animator.requestTransition(this._transitionCallback)):this.clear()}}function ZC(t){const e={},n=["string","number","boolean"],r=["wheelDelta","wheelDeltaX","wheelDeltaY"];for(const i in t){const o=i;!r.includes(i)&&n.includes(typeof t[o])&&(e[o]=t[o])}return e}function KC(t,e,n=!0){let r,i=s=>{};return function(...a){return new Promise((u,c)=>{const f=()=>{clearTimeout(r),i=l=>{},u(t(...a))};n&&i("debounced"),clearTimeout(r),i=c,r=setTimeout(f,e)})}}const Kh=new Map;async function qC(t,e,n){const r=t.symbol;let i=Kh.get(r)??await $C(t.symbol);return i?(Kh.set(r,i),nt`<div class="title"><strong>${i.name}</strong> ${i.description}</div><p class="summary">${i.summary}</p><p class="source">Source: NCBI RefSeq Gene</p>`):null}async function JC(t){console.log("Searching: "+t);const e={mode:"cors"},r=(await fetch(`https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=gene&term=${t}[GENE]&sort=relevance&retmode=json`,e).then(i=>i.json())).esearchresult.idlist[0];return r?(await fetch(`https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=gene&id=${r}&retmode=json`,e).then(s=>s.json())).result[r]:null}const _C=KC(JC,500);function $C(t){return _C(t)}const eE=oe(".4~r"),tE=oe(".4~e");function nE(t){return t===null?nt`<span class="na">NA</span>`:W(t)?t.substring(0,30):Number.isInteger(t)?""+t:me(t)?Math.abs(t)>Math.pow(10,8)||Math.abs(t)<Math.pow(10,-8)?tE(t):eE(t):ai(t)?t?"True":"False":"?"+typeof t+" "+t}async function rE(t,e,n){const r=(u,c)=>{var f;for(const[l,h]of Object.entries(e.encoders))if((f=h==null?void 0:h.accessor)!=null&&f.fields.includes(u))switch(l){case"color":case"fill":case"stroke":return nt`<span class="color-legend" style="${`background-color: ${h(c)}`}"></span>`}return""},i=Object.entries(t).filter(([u,c])=>!u.startsWith("_"));if(i.length===0)return;const o=nt`<table class="attributes">${i.map(([u,c])=>nt`<tr><th>${u}</th><td>${nE(c)} ${r(u,t)}</td></tr>`)}</table>`,s=e.unitView.getTitleText(),a=s?nt`<div class="title"><strong>${s}</strong></div>`:"";return nt`${a}${o}`}class iE extends Rh{constructor(e,n){super({vconcat:[]},e,void 0,"implicitRoot",1),n.parent=this,this.appendChild(n)}}N("index",ds,["continuous"]),N("locus",nm,["continuous"]),N("null",Xh,[]),Cc("fasta",WC);class qh{constructor(e,n,r={}){this.container=e,this.spec=n,this.accessorFactory=new j1,this.viewFactory=new Hv,this.namedDataProviders=[],this.animator=new GC(()=>this.renderAll()),this.genomeStore=void 0,this.viewVisibilityPredicate=i=>i.isVisibleInSpec(),this._renderingContext=void 0,this._pickingContext=void 0,this._dirtyPickingBuffer=!1,this._currentHover=void 0,this._wheelInertia=new XC(this.animator),this._keyboardListeners=new Map,this._eventListeners=new Map,this.tooltipHandlers={default:rE,refseqgene:qC,...r.tooltipHandlers??{}},this.viewRoot=void 0}registerNamedDataProvider(e){this.namedDataProviders.unshift(e)}getNamedDataFromProvider(e){for(const n of this.namedDataProviders){const r=n(e);if(r)return r}}updateNamedData(e,n){const r=this.viewRoot.context.dataFlow.findNamedDataSource(e);if(!r)throw new Error("No such named data source: "+e);r.dataSource.updateDynamicData(n);for(const i of r.hosts)i.visit(o=>{for(const s of Object.values(o.resolutions.scale))s.reconfigure()});this.animator.requestRender()}broadcast(e,n){const r={type:e,payload:n};this.viewRoot.visit(i=>i.handleBroadcast(r))}_prepareContainer(){this.container.classList.add("genome-spy"),this.container.classList.add("loading"),this._glHelper=new iw(this.container,()=>{if(this.viewRoot){const e=this.viewRoot.getSize().addPadding(this.viewRoot.getOverhang()),n=r=>r.grow>0?void 0:r.px;return{width:n(e.width),height:n(e.height)}}}),this.loadingMessageElement=document.createElement("div"),this.loadingMessageElement.className="loading-message",this.loadingMessageElement.innerHTML='<div class="message">Loading<span class="ellipsis">...</span></div>',this.container.appendChild(this.loadingMessageElement),this.tooltip=new vA(this.container),this.loadingMessageElement.querySelector(".message").addEventListener("transitionend",()=>{this.loadingMessageElement.style.display="none"})}destroy(){this.container.classList.remove("genome-spy"),this.container.classList.remove("loading");for(const[e,n]of this._keyboardListeners)for(const r of n)document.removeEventListener(e,r);for(this._glHelper.finalize();this.container.firstChild;)this.container.firstChild.remove()}async _prepareViewsAndData(){this.spec.genome&&(this.genomeStore=new UC(this),await this.genomeStore.initialize(this.spec.genome));const e=this,n={dataFlow:new Qh,accessorFactory:this.accessorFactory,glHelper:this._glHelper,animator:this.animator,genomeStore:this.genomeStore,fontManager:new jC(this._glHelper),requestLayoutReflow:()=>{},updateTooltip:this.updateTooltip.bind(this),getNamedDataFromProvider:this.getNamedDataFromProvider.bind(this),getCurrentHover:()=>this._currentHover,addKeyboardListener:(a,u)=>{document.addEventListener(a,u);let c=this._keyboardListeners.get(a);c||(c=[],this._keyboardListeners.set(a,c)),c.push(u)},isViewVisible:e.viewVisibilityPredicate,isViewSpec:a=>e.viewFactory.isViewSpec(a),createView:function(a,u,c){return e.viewFactory.createView(a,n,u,c)}},r=this.spec;r.datasets&&this.registerNamedDataProvider(a=>r.datasets[a]),this.viewRoot=n.createView(r,null,"viewRoot"),await Vh(this.viewRoot),(this.viewRoot instanceof we||this.viewRoot instanceof tn)&&(this.viewRoot=new iE(n,this.viewRoot)),TC(this.viewRoot),PC(this.viewRoot),this._glHelper.invalidateSize();const i=[];this.viewRoot.visit(a=>{a instanceof we&&i.push(a)});const o=SC(this.viewRoot,n.dataFlow);IC(o),this.broadcast("dataFlowBuilt",o),o.dataSources.forEach(a=>console.log(a.subtreeToString())),i.forEach(a=>a.mark.initializeEncoders());const s=Promise.all(i.map(a=>a.mark.initializeGraphics()));for(const a of i)o.addObserver(u=>{a.mark.initializeData(),a.mark.updateGraphicsData()},a);await n.fontManager.waitUntilReady(),o.initialize(),await Promise.all(o.dataSources.map(a=>a.load())),this.viewRoot.visit(a=>{for(const u of Object.values(a.resolutions.scale))u.reconfigure()}),this.broadcast("dataLoaded"),await s,this.viewRoot.visit(a=>{for(const u of Object.values(a.resolutions.scale))this._glHelper.createRangeTexture(u)});for(const a of i)a.mark.finalizeGraphicsInitialization();n.requestLayoutReflow=this.computeLayout.bind(this),this.viewRoot.visit(a=>wo(a,"size")),this._glHelper.invalidateSize()}async launch(){try{return this._prepareContainer(),await this._prepareViewsAndData(),this.registerMouseEvents(),this.computeLayout(),this.animator.requestRender(),this._glHelper.addEventListener("resize",()=>{this.computeLayout(),this.renderAll()}),!0}catch(e){const n=`${e.view?`At "${e.view.getPathString()}": `:""}${e.toString()}`;return console.error(e.stack),oE(this.container,n),!1}finally{this.container.classList.remove("loading"),window.setTimeout(()=>{this.loadingMessageElement.style.display="none"},2e3)}}registerMouseEvents(){const e=this._glHelper.canvas,n=r=>{var i;if(r instanceof MouseEvent){r.type=="mousemove"&&(this.tooltip.handleMouseMove(r),this._tooltipUpdateRequested=!1,r.buttons==0&&this.renderPickingFramebuffer());const o=e.getBoundingClientRect(),s=new NC(r.clientX-o.left-e.clientLeft,r.clientY-o.top-e.clientTop),a=u=>{this.viewRoot.propagateInteractionEvent(new kC(s,u)),this._tooltipUpdateRequested||this.tooltip.clear()};if(r.type!="wheel"&&this._wheelInertia.cancel(),r.type=="mousemove")this._handlePicking(s.x,s.y);else if(r.type=="mousedown"||r.type=="mouseup")this.renderPickingFramebuffer();else if(r.type=="wheel"){this._tooltipUpdateRequested=!1;const u=r;if(Math.abs(u.deltaX)>Math.abs(u.deltaY))this._currentHover=null,this._wheelInertia.cancel();else{const c=ZC(u);this._wheelInertia.setMomentum(u.deltaY*(u.deltaMode?80:1),f=>{const l=new WheelEvent("wheel",{...c,deltaMode:0,deltaX:0,deltaY:f});a(l)}),u.preventDefault();return}}if(r.type=="click"){const u=this._currentHover?{type:r.type,viewPath:[...this._currentHover.mark.unitView.getAncestors()].map(c=>c.name).reverse(),datum:this._currentHover.datum}:{type:r.type,viewPath:null,datum:null};(i=this._eventListeners.get("click"))==null||i.forEach(c=>c(u))}a(r)}};["mousedown","mouseup","wheel","click","mousemove","gesturechange","contextmenu"].forEach(r=>e.addEventListener(r,n)),e.addEventListener("mousedown",()=>{document.addEventListener("mouseup",()=>this.tooltip.popEnabledState(),{once:!0}),this.tooltip.pushEnabledState(!1)}),e.addEventListener("dragstart",r=>r.stopPropagation())}_handlePicking(e,n){var o;const r=this._glHelper.readPickingPixel(e,n),i=r[0]|r[1]<<8|r[2]<<16;if(i==0){this._currentHover=null;return}if(i!==((o=this._currentHover)==null?void 0:o.uniqueId)&&(this._currentHover=null),this._currentHover||this.viewRoot.visit(s=>{if(s instanceof we){if(s.mark.isPickingParticipant()){const a=s.mark.encoders.uniqueId.accessor;s.getCollector().visitData(u=>{a(u)==i&&(this._currentHover={mark:s.mark,datum:u,uniqueId:i})})}if(this._currentHover)return Zr}}),this._currentHover){const s=this._currentHover.mark;this.updateTooltip(this._currentHover.datum,async a=>{if(!s.isPickingParticipant())return;const u=s.properties.tooltip;if(u!==null){const c=(u==null?void 0:u.handler)??"default",f=this.tooltipHandlers[c];if(!f)throw new Error("No such tooltip handler: "+c);return f(a,s,u==null?void 0:u.params)}})}}updateTooltip(e,n){if(!this._tooltipUpdateRequested||!e)this.tooltip.updateWithDatum(e,n),this._tooltipUpdateRequested=!0;else throw new Error("Tooltip has already been updated! Duplicate event handler?")}computeLayout(){const e=this.viewRoot;if(!e)return;this.broadcast("layout");const n=this._glHelper.getLogicalCanvasSize();if(isNaN(n.width)||isNaN(n.height)){console.log(`NaN in canvas size: ${n.width}x${n.height}. Skipping computeLayout().`);return}this._renderingContext=new Wh({picking:!1},this._glHelper),this._pickingContext=new Wh({picking:!0},this._glHelper),e.render(new LC(this._renderingContext,this._pickingContext),zn.create(0,0,n.width,n.height)),this.broadcast("layoutComputed")}renderAll(){var e;(e=this._renderingContext)==null||e.renderDeferred(),this._dirtyPickingBuffer=!0}renderPickingFramebuffer(){this._dirtyPickingBuffer&&(this._pickingContext.renderDeferred(),this._dirtyPickingBuffer=!1)}getSearchableViews(){const e=[];return this.viewRoot.visit(n=>{n instanceof we&&n.getAccessor("search")&&e.push(n)}),e}getNamedScaleResolutions(){const e=new Map;return this.viewRoot.visit(n=>{for(const r of Object.values(n.resolutions.scale))r.name&&e.set(r.name,r)}),e}}function oE(t,e){const n=document.createElement("div");n.className="message-box";const r=document.createElement("div");r.textContent=e,n.appendChild(r),t.appendChild(n)}const sE="data:image/svg+xml;base64,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";async function aE(t,e,n={}){let r;if(W(t)){if(r=document.querySelector(t),!r)throw new Error(`No such element: ${t}`)}else if(t instanceof HTMLElement)r=t;else throw new Error(`Invalid element: ${t}`);let i;try{const o=Le(e)?e:await Jh(e);if(o.baseUrl??(o.baseUrl=""),o.width??(o.width="container"),o.padding??(o.padding=10),r==document.body){const s=document.createElement("div");s.style.position="fixed",s.style.inset="0",s.style.overflow="hidden",r.appendChild(s),r=s}i=new qh(r,o,n),uE(i,n),await i.launch()}catch(o){r.innerText=o.toString(),console.error(o)}return{finalize(){for(i.destroy();r.firstChild;)r.firstChild.remove()},addEventListener(o,s){const a=i._eventListeners;let u=a.get(o);u||(u=new Set,a.set(o,u)),u.add(s)},removeEventListener(o,s){var u;(u=i._eventListeners.get(o))==null||u.delete(s)},getScaleResolutionByName(o){return i.getNamedScaleResolutions().get(o)},updateNamedData:i.updateNamedData.bind(i)}}function uE(t,e){e.namedDataProvider&&t.registerNamedDataProvider(e.namedDataProvider)}async function Jh(t){let e;try{e=JSON.parse(await Si().load(t))}catch(n){throw new Error(`Could not load or parse configuration: ${t}, reason: ${n.message}`)}if(!e.baseUrl){const n=t.match(/^[^?#]*\//);e.baseUrl=n&&n[0]||"./"}return e}P.GenomeSpy=qh,P.embed=aE,P.html=nt,P.icon=sE,P.loadSpec=Jh,Object.defineProperty(P,Symbol.toStringTag,{value:"Module"})});