@genome-spy/core 0.28.0 → 0.28.1

package/LICENSE

@@ -0,0 +1,24 @@
+BSD 2-Clause License
+
+Copyright (c) 2018-2022 Kari Lavikka
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+1. Redistributions of source code must retain the above copyright notice, this
+   list of conditions and the following disclaimer.
+
+2. Redistributions in binary form must reproduce the above copyright notice,
+   this list of conditions and the following disclaimer in the documentation
+   and/or other materials provided with the distribution.
+
+THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
+AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
+IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.

package/dist/index.js

@@ -144,7 +144,7 @@ if(scale<1.0){if(uSqueeze){vec2 scaleFadeExtent=vec2(3.0,6.0)/size;if(scale<scal
  * All rights reserved.
  *
  * BSD-3-Clause License: https://github.com/vega/vega-lite/blob/master/LICENSE
- */const Yw="locus",Ww="index";var Xw=5;function Zw(t){const e=t.type;return!t.bins&&(e===bn||e===wr||e===vr)}function uh(t){return Pe(t)&&![Ze,Ww,Yw].includes(t)}function ch(t){return t||{warn:(e,...n)=>console.warn(e,...n)}}var Kw=fi(["set","modified","clear","type","scheme","schemeExtent","schemeCount","domain","domainMin","domainMid","domainMax","domainRaw","domainImplicit","nice","zero","bins","range","rangeStep","round","reverse","interpolate","interpolateGamma","zoom","fp64","name"]);function lh(t,e,n){n=ch(n);for(const r in t)if(!Kw[r]){if(r==="padding"&&uh(e.type))continue;ge(e[r])?e[r](t[r]):n.warn("Unsupported scale property: "+r)}rv(e,t,nv(e,t,$w(e,t,n)))}function qw(t,e){const n=Jw(t),r=O(n);if(!r)throw new Error("Unknown scale type: "+n);const i=r();return lh(t,i,e),i}function Jw(t){var e=t.type,n="",r;return e===Ze?Ze+"-"+bn:(_w(t)&&(r=t.rawDomain?t.rawDomain.length:t.domain?t.domain.length+ +(t.domainMid!=null):0,n=r===2?Ze+"-":r===3?wn+"-":""),(n+e||bn).toLowerCase())}function _w(t){const e=t.type;return Pe(e)&&e!==Vl&&e!==Yl&&(t.scheme||t.range&&t.range.length&&t.range.every(Z))}function $w(t,e,n){if(!t.domain)return 0;n=ch(n);var r=ev(t,e.domainRaw,n);if(r>-1)return r;var i=e.domain,o=t.type,s=e.zero||e.zero===void 0&&Zw(t),a,u;return i?(uh(o)&&e.padding&&i[0]!==Ne(i)&&(i=tv(o,i,e.range,e.padding,e.exponent,e.constant)),(s||e.domainMin!=null||e.domainMax!=null||e.domainMid!=null)&&(a=(i=i.slice()).length-1||1,s&&(i[0]>0&&(i[0]=0),i[a]<0&&(i[a]=0)),e.domainMin!=null&&(i[0]=e.domainMin),e.domainMax!=null&&(i[a]=e.domainMax),e.domainMid!=null&&(u=e.domainMid,(u<i[0]||u>i[a])&&n.warn("Scale domainMid exceeds domain min or max.",u),i.splice(a,0,u))),t.domain(fh(o,i,n)),o===Xs&&t.unknown(e.domainImplicit?ps:void 0),e.nice&&t.nice&&t.nice(e.nice!==!0&&sh(t,e.nice)||null),i.length):0}function ev(t,e,n){return e?(t.domain(fh(t.type,e,n)),e.length):-1}function tv(t,e,n,r,i,o){var s=Math.abs(Ne(n)-n[0]),a=s/(s-2*r),u=t===bt?xu(e,null,a):t===vr?Lo(e,null,a,.5):t===wr?Lo(e,null,a,i||1):t===Hi?hd(e,null,a,o||1):Au(e,null,a);return e=e.slice(),e[0]=u[0],e[e.length-1]=u[1],e}function fh(t,e,n){if(_l(t)){var r=Math.abs(e.reduce(function(i,o){return i+(o<0?-1:o>0?1:0)},0));r!==e.length&&n.warn("Log scale domain includes zero: "+li(e))}return e}function nv(t,e,n){let r=e.bins;if(r&&!Me(r)){const i=(r.start==null||r.stop==null)&&t.domain(),o=r.start==null?i[0]:r.start,s=r.stop==null?Ne(i):r.stop,a=r.step;a||X("Scale bins parameter missing step property."),r=Kn(o,s+a,a)}return r?t.bins=r:t.bins&&delete t.bins,t.type===Ks&&(r?!e.domain&&!e.domainRaw&&(t.domain(r),n=r.length):t.bins=t.domain()),n}function rv(t,e,n){var r=t.type,i=e.round||!1,o=e.range;if(e.rangeStep!=null)o=iv(r,e,n);else if(e.scheme&&(o=ov(r,e,n),ge(o))){if(t.interpolator)return t.interpolator(o);X(`Scale type ${r} does not support interpolating color schemes.`)}if(o&&ji(r))return t.interpolator(Vi(Za(o,e.reverse),e.interpolate,e.interpolateGamma));o&&e.interpolate&&t.interpolate?t.interpolate($l(e.interpolate,e.interpolateGamma)):ge(t.round)?t.round(i):ge(t.rangeRound)&&t.interpolate(i?yr:xt),o&&t.range(Za(o,e.reverse))}function iv(t,e,n){t!==Zl&&t!==Zs&&X("Only band and point scales support rangeStep.");var r=(e.paddingOuter!=null?e.paddingOuter:e.padding)||0,i=t===Zs?1:(e.paddingInner!=null?e.paddingInner:e.padding)||0;return[0,e.rangeStep*Ys(n,i,r)]}function ov(t,e,n){var r=e.schemeExtent,i,o;return Me(e.scheme)?o=Vi(e.scheme,e.interpolate,e.interpolateGamma):(i=e.scheme.toLowerCase(),o=Js(i),o||X(`Unrecognized scheme name: ${e.scheme}`)),n=t===Xl?n+1:t===Ks?n-1:t===Ws||t===Wl?+e.schemeCount||Xw:n,ji(t)?hh(o,r,e.reverse):ge(o)?gA(hh(o,r),n):t===Xs?o:o.slice(0,n)}function hh(t,e,n){return ge(t)&&(e||n)?pA(t,Za(e||[0,1],n)):t}function Za(t,e){return e?t.slice().reverse():t}const dh=se(",d");function sv(t,e){return t.chrom+":"+dh(Math.floor(t.pos+1))+"-"+(t.chrom!=e.chrom?e.chrom+":":"")+dh(Math.ceil(e.pos))}const av="https://genomespy.app/data/genomes/";class uv{constructor(e){if(this.config=e,!this.config.contigs&&typeof this.config.name!="string")throw new Error("No name has been defined for the genome assembly!");this.chromosomes=[],this.cumulativeChromPositions=new Map,this.chromosomesByName=new Map,this.startByIndex=[],this.totalSize=0,this.config.contigs&&this.setChromSizes(this.config.contigs)}get name(){return this.config.name}async load(e){if(!this.config.contigs){this.config.baseUrl?this.baseUrl=/^http(s)?/.test(this.config.baseUrl)?this.config.baseUrl:e+"/"+this.config.baseUrl:this.baseUrl=av;try{this.setChromSizes(cv(await Di({baseURL:this.baseUrl}).load(`${this.config.name}/${this.name}.chrom.sizes`)))}catch(n){throw new Error(`Could not load chrom sizes: ${n.message}`)}}}setChromSizes(e){let n=0;this.startByIndex=[0];for(let r=0;r<e.length;r++){this.startByIndex.push(n);const i=e[r].size,o={...e[r],continuousStart:n,continuousEnd:n+i,continuousInterval:[n,n+i],index:r,number:r+1,odd:!(r&1)};this.chromosomes.push(o);const s=o.name.replace(/^chr/i,"");for(const a of["chr"+s,"CHR"+s,"Chr"+s,o.number,""+o.number,s,o.name])this.cumulativeChromPositions.set(a,n),this.chromosomesByName.set(a,o);n+=o.size}this.totalSize=n}getExtent(){return[0,this.totalSize]}toContinuous(e,n){let r=this.cumulativeChromPositions.get(e);if(r===void 0)throw new Error("Unknown chromosome/contig: "+e);return r+ +n}toChromosome(e){if(e>=this.totalSize)return;e=Math.floor(e);const n=an(this.startByIndex,e)-1;if(n>0&&n<=this.chromosomes.length)return this.chromosomes[n-1]}toChromosomal(e){const n=this.toChromosome(e);if(!!n)return{chrom:n.name,pos:Math.floor(e)-n.continuousStart}}getChromosome(e){return this.chromosomesByName.get(e)}formatInterval(e){return sv(...this.toChromosomalInterval(e))}toChromosomalInterval(e){const n=this.toChromosomal(e[0]+.5),r=this.toChromosomal(e[1]-.5);return r.pos+=1,[n,r]}toContinuousInterval(e){var i,o,s;let[n,r]=e;return r||(r=n),[this.toContinuous(n.chrom,(i=n.pos)!=null?i:0),this.toContinuous(r.chrom,(s=r.pos)!=null?s:(o=this.chromosomesByName.get(r.chrom))==null?void 0:o.size)]}parseInterval(e){const n=e.match(/^(chr[0-9A-Z]+)(?::([0-9,]+)(?:-(?:(chr[0-9A-Z]+):)?([0-9,]+))?)?$/);if(n){const r=n[1];if(n.slice(2).every(a=>a===void 0)){const a=this.getChromosome(r);return a?[a.continuousStart,a.continuousEnd]:void 0}const i=n[3]||r,o=parseInt(n[2].replace(/,/g,"")),s=n[4]!==void 0?parseInt(n[4].replace(/,/g,"")):o;return[this.toContinuous(r,o-1),this.toContinuous(i,s)]}}}function cv(t){return Td(t).filter(e=>/^chr[0-9A-Z]+$/.test(e[0])).map(([e,n])=>({name:e,size:parseInt(n)}))}function ph(t){return ke(t)&&"chrom"in t}function lv(t){return t.every(ph)}class qr extends Array{constructor(){super(),this.type=void 0}extend(e){return this}extendAll(e){if(e instanceof qr&&e.type!=this.type)throw new Error(`Cannot combine different types of domains: ${this.type} and ${e.type}`);for(const n of e)this.extend(n);return this}extendAllWithAccessor(e,n){for(const r of e)this.extend(n(r));return this}}class Ka extends qr{constructor(){super(),this.type="quantitative"}extend(e){return e==null||Number.isNaN(e)?this:(e=+e,this.length?e<this[0]?this[0]=e:e>this[1]&&(this[1]=e):(this.push(e),this.push(e)),this)}}class gh extends qr{constructor(){super(),this.type="ordinal",this.uniqueValues=new Set}extend(e){return e==null||Number.isNaN(e)?this:(this.uniqueValues.has(e)||(this.uniqueValues.add(e),this.push(e)),this)}}class mh extends gh{constructor(){super(),this.type="nominal"}}class fv extends qr{constructor(e){super();let n=0;for(let r=1;r<e.length;r++)n+=Math.sign(e[r]-e[r-1]);if(Math.abs(n)!=e.length-1)throw new Error("Piecewise domain must be strictly increasing or decreasing: "+JSON.stringify(e));e.forEach(r=>this.push(r))}extend(e){if(this.includes(e))return this;throw new Error("Piecewise domains are immutable and cannot be unioned!")}}const Ah={quantitative:Ka,index:Ka,locus:Ka,nominal:mh,ordinal:gh};function xh(t,e){if(t=="quantitative"&&hv(e)){const n=new fv(e);return n.type=t,n}else if(Ah[t]){const n=new Ah[t];return n.type=t,e&&n.extendAll(e),n}throw new Error("Unknown type: "+t)}function hv(t){return t&&t.length>0&&t.length!=2&&t.every(e=>typeof e=="number")}function dv(t){return((t*=2)<=1?t*t:--t*(2-t)+1)/2}const yh="quantitative",bh="ordinal",wh="nominal",vh="locus",pv="index";class gv{constructor(e){this.channel=e,this.members=[],this.type=null,this._zoomExtent=void 0,this._domainListeners=new Set,this.name=void 0,this._scale=void 0}addEventListener(e,n){if(e!="domain")throw new Error("Unsupported event type: "+e);this._domainListeners.add(n)}removeEventListener(e,n){if(e!="domain")throw new Error("Unsupported event type: "+e);this._domainListeners.delete(n)}_notifyDomainListeners(){for(const e of this._domainListeners.values())e({type:"domain",scaleResolution:this})}pushUnitView(e,n){var s;const r=aa(e,n),i=r.type,o=(s=r==null?void 0:r.scale)==null?void 0:s.name;if(o){if(this.name!==void 0&&o!=this.name)throw new Error(`Shared scales have conflicting names: "${o}" vs. "${this.name}"!`);this.name=o}if(!this.type)this.type=i;else if(i!==this.type&&!zr(n))throw new Error(`Can not use shared scale for different data types: ${this.type} vs. ${i}. Use "resolve: independent" for channel ${this.channel}`);this.members.push({view:e,channel:n})}isExplicitDomain(){return!!this.getConfiguredDomain()}_getMergedScaleProps(){return kn(this,"mergedScaleProps",()=>{const e=this.members.map(n=>aa(n.view,n.channel).scale).filter(n=>n!==void 0);return So(e,"scale",["domain"])})}getScaleProps(){return kn(this,"scaleProps",()=>{var i,o;const e=this._getMergedScaleProps();if(e===null||e.type=="null")return{type:"null"};const n={...this._getDefaultScaleProperties(this.type),...e};n.type||(n.type=mv(this.channel,this.type));const r=this.getInitialDomain();return r&&r.length>0?n.domain=r:Wt(n.type)&&(n.domain=new mh),!n.domain&&n.domainMid!==void 0&&(n.domain=[(i=n.domainMin)!=null?i:0,(o=n.domainMax)!=null?o:1]),this.channel=="y"&&Wt(n.type)&&n.reverse==null&&(n.reverse=!0),n.range&&n.scheme&&delete n.scheme,!("zoom"in n)&&["index","locus"].includes(n.type)&&(n.zoom=!0),Av(n,this.channel),n})}getInitialDomain(){var e;return(e=this.getConfiguredDomain())!=null?e:this.type==vh?this.getGenome().getExtent():this.getDataDomain()}getConfiguredDomain(){return this._reduceDomains(e=>zr(e.channel)?void 0:e.view.getConfiguredDomain(e.channel))}getDataDomain(){return this._reduceDomains(e=>zr(e.channel)?void 0:e.view.extractDataDomain(e.channel))}reconfigure(){if(this._scale&&this._scale.type!="null"){V0(this,"scaleProps");const e=this.getScaleProps();lh(e,this._scale),Pe(this._scale.type)&&(this._zoomExtent=this._getZoomExtent())}}getScale(){if(this._scale)return this._scale;const e=this.getScaleProps(),n=qw(e);return this._scale=n,nm(n)&&n.genome(this.getGenome()),Pe(n.type)&&(this._zoomExtent=this._getZoomExtent()),n}getDomain(){return this.getScale().domain()}getComplexDomain(){var e,n;return(n=(e=this.getGenome())==null?void 0:e.toChromosomalInterval(this.getDomain()))!=null?n:this.getDomain()}isZoomed(){return this.isZoomable()&&rf(this.getInitialDomain(),this.getDomain())}isZoomable(){if(!yf(this.channel))return!1;const e=this.getScale().type;return["linear","locus","index","log","pow","sqrt"].includes(e)?!!this.getScaleProps().zoom:!1}zoom(e,n,r){if(!this.isZoomable())return!1;const i=this.getScale(),o=i.domain();let s=[...o],a=i.invert(n);switch(this.getScaleProps().reverse&&(r=-r),"align"in i&&(a+=i.align()),i.type){case"linear":case"index":case"locus":s=cd(s,r||0),s=Au(s,a,e);break;case"log":s=ld(s,r||0),s=xu(s,a,e);break;case"pow":case"sqrt":{const u=i;s=fd(s,r||0,u.exponent()),s=Lo(s,a,e,u.exponent());break}default:throw new Error("Zooming is not implemented for: "+i.type)}return this._zoomExtent&&(s=dd(s,this._zoomExtent[0],this._zoomExtent[1])),[0,1].some(u=>s[u]!=o[u])?(i.domain(s),this._notifyDomainListeners(),!0):!1}async zoomTo(e,n=!1){var a;if(ui(n)&&(n=n?700:0),!this.isZoomable())throw new Error("Not a zoomable scale!");const r=this.fromComplexInterval(e),i=(a=this.members[0])==null?void 0:a.view.context.animator,o=this.getScale(),s=o.domain();if(n>0&&s.length==2){const u=s[1]-s[0],c=s[0]+u/2,f=r[1]-r[0],l=r[0]+f/2,h=yl([c,0,u],[l,0,f]).rho(.7);await i.transition({duration:n/1e3*h.duration,easingFunction:dv,onUpdate:p=>{const[d,,g]=h(p);o.domain([d-g/2,d+g/2]),this._notifyDomainListeners()}}),o.domain(r),this._notifyDomainListeners()}else o.domain(r),i==null||i.requestRender(),this._notifyDomainListeners()}resetZoom(){if(!this.isZoomable())throw new Error("Not a zoomable scale!");const e=this.getDomain(),n=this.getInitialDomain();return[0,1].some(r=>n[r]!=e[r])?(this._scale.domain(n),this._notifyDomainListeners(),!0):!1}getZoomLevel(){return this.isZoomable()?ci(this._zoomExtent)/ci(this.getScale().domain()):1}_getZoomExtent(){const e=this.getScaleProps(),n=e.zoom;if(xv(n)&&Me(n.extent))return this.fromComplexInterval(n.extent);if(n)return e.type=="locus"?this.getGenome().getExtent():this._scale.domain()}_getDefaultScaleProperties(e){const n=this.channel,r={};return this.isExplicitDomain()&&(r.zero=!1),Nr(n)?r.nice=!this.isExplicitDomain():qt(n)?r.scheme=e==wh?"tableau10":e==bh?"blues":"viridis":Ji(n)?r.range=wf(n):n=="size"?r.range=[0,400]:n=="angle"&&(r.range=[0,360]),r}getGenome(){var n;if(this.type!=="locus")return;const e=(n=this.members[0].view.context.genomeStore)==null?void 0:n.getGenome();if(!e)throw new Error("No genome has been defined!");return e}invertToComplex(e){const n=this.getScale();if("invert"in n){const r=n.invert(e);return this.toComplex(r)}else throw new Error("The scale does not support inverting!")}toComplex(e){const n=this.getGenome();return n?n.toChromosomal(e):e}fromComplex(e){return ph(e)?this.getGenome().toContinuous(e.chrom,e.pos):e}fromComplexInterval(e){return this.type==="locus"&&lv(e)?this.getGenome().toContinuousInterval(e):e}_getViewPaths(){return this.members.map(e=>e.view.getPathString()).join(", ")}_reduceDomains(e){const n=this.members.map(e).filter(r=>!!r);if(n.length)return n.reduce((r,i)=>r.extendAll(i))}}function mv(t,e){if(e==pv||e==vh){if(yf(t))return e;throw new Error(`${t} does not support ${e} data type. Only positional channels do.`)}const n={x:["band","band","linear"],y:["band","band","linear"],size:[void 0,"point","linear"],opacity:[void 0,"point","linear"],fillOpacity:[void 0,"point","linear"],strokeOpacity:[void 0,"point","linear"],color:["ordinal","ordinal","linear"],fill:["ordinal","ordinal","linear"],stroke:["ordinal","ordinal","linear"],strokeWidth:[void 0,void 0,"linear"],shape:["ordinal","ordinal",void 0],dx:[void 0,void 0,"null"],dy:[void 0,void 0,"null"],angle:[void 0,void 0,"linear"]},i=["uniqueId","facetIndex","semanticScore","search","text","sample"].includes(t)?"null":n[t]?n[t][[wh,bh,yh].indexOf(e)]:e==yh?"linear":"ordinal";if(i===void 0)throw new Error(`Channel "${t}" is not compatible with "${e}" data type. Use of a proper scale may be needed.`);return i}function Av(t,e){Nr(e)&&t.type!=="ordinal"&&(t.range=[0,1]),e=="opacity"&&Pe(t.type)&&(t.clamp=!0)}function xv(t){return ke(t)}function qa(...t){for(const e of t)if(e!==void 0)return e}class yv{constructor(e){this.channel=e,this.members=[]}get scaleResolution(){var e;return(e=Cn(this.members))==null?void 0:e.view.getScaleResolution(this.channel)}pushUnitView(e,n){const r=e.getScaleResolution(this.channel);if(!r)throw new Error("Cannot find a scale resolution!");if(this.scaleResolution&&r!==this.scaleResolution)throw new Error("Shared axes must have a shared scale!");this.members.push({view:e,channel:n})}getAxisProps(){return kn(this,"axisProps",()=>{const e=this.members.map(n=>{const r=n.view.mark.encoding[n.channel];return"axis"in r&&r.axis});return e.length>0&&e.some(n=>n===null)?null:So(e.filter(n=>n!==void 0),"axis",["title"])})}getTitle(){const e=o=>{var a;const s=aa(o.view,o.channel);if(!Ue(s))return{member:o,explicitTitle:qa((a=s.axis)==null?void 0:a.title,s.title),implicitTitle:qa(Lr(s)?s.field:void 0,ua(s)?s.expr:void 0)}},n=this.members.map(e),r=n.filter(o=>{var s;if(zr(o.member.channel)&&!o.explicitTitle){const a=En(o.member.channel);return((s=n.find(u=>u.member.view==o.member.view&&u.member.channel==a))==null?void 0:s.explicitTitle)===void 0}return!0}),i=new Set(r.map(o=>qa(o.explicitTitle,o.implicitTitle)).filter(Z));return i.size?[...i].join(", "):null}}class Ch extends ih{constructor(e,n,r,i){super(e,n,r,i),this.spec=e}}class nn extends Nn{constructor(e,n,r,i){super(e,n,r,i),this.spec=e,this.children=(e.layer||[]).map((o,s)=>{if(nu(o)||tu(o))return n.createView(o,this,"layer"+s);throw new Error("LayerView accepts only unit or layer specs as children!")})}*[Symbol.iterator](){for(const e of this.children)yield e}render(e,n,r={}){if(!!this.isVisible()){e.pushView(this,n);for(const i of this.children)i.render(e,n,r);e.popView(this)}}propagateInteractionEvent(e){this.handleInteractionEvent(void 0,e,!0),this.children.length&&this.children.at(-1).propagateInteractionEvent(e),!e.stopped&&this.handleInteractionEvent(void 0,e,!1)}}class Eh{constructor(e,n){this.n=e,this.maxCols=n!=null?n:1/0}get nRows(){return this.maxCols==1/0?1:Math.ceil(this.n/this.maxCols)}get nCols(){return Math.min(this.n,this.maxCols)}get rowIndices(){const e=[],n=this.nCols,r=this.nRows;for(let i=0;i<r;i++){const o=[];e.push(o);for(let s=0;s<n;s++){const a=i*n+s;a<this.n&&o.push(a)}}return e}get colIndices(){const e=[],n=this.nCols,r=this.nRows;for(let i=0;i<n;i++){const o=[];e.push(o);for(let s=0;s<r;s++){const a=s*n+i;a<this.n&&o.push(a)}}return e}getCellIndex(e,n){let r=0;if(this.maxCols==1/0)r=n==0?e:void 0;else{if(e>=this.maxCols)return;r=n*this.nCols+e}return r<this.n?r:void 0}getCellCoords(e){if(!(e<0||e>=this.n))return[e%this.nCols,Math.floor(e/this.nCols)]}}function ct(t){return()=>t}const lt=class{static create(e,n,r,i){return new lt(ct(e),ct(n),ct(r),ct(i))}_offset(e,n){const r=this["_"+e];if(n===0)return r;switch(typeof n){case"number":return()=>r()+n;case"function":return()=>r()+n();default:throw new Error("Not a number of function")}}_passThrough(e){return this._offset(e,0)}constructor(e,n,r,i){this._x=e,this._y=n,this._width=r,this._height=i}get x(){return this._x()}get y(){return this._y()}get width(){return this._width()}get height(){return this._height()}get x2(){return this._x()+this._width()}get y2(){return this._y()+this._height()}equals(e){return e?this===e||this.x===e.x&&this.y===e.y&&this.width===e.width&&this.height===e.height:!1}modify(e){if(!Object.keys(e).length)return this;const n=r=>{const i=e[r];return typeof i=="number"?ct(i):typeof i=="function"?i:this._passThrough(r)};return new lt(n("x"),n("y"),n("width"),n("height"))}translate(e,n){return e===0&&n===0?this:new lt(this._offset("x",e),this._offset("y",n),this._passThrough("width"),this._passThrough("height"))}translateBy(e){return this.translate(e.x,e.y)}expand(e,n=1){return e.left==0&&e.top==0&&e.right==0&&e.bottom==0?this:new lt(e.left?this._offset("x",-e.left*n):this._passThrough("x"),e.top?this._offset("y",-e.top*n):this._passThrough("y"),e.width?this._offset("width",e.width*n):this._passThrough("width"),e.height?this._offset("height",e.height*n):this._passThrough("height"))}shrink(e){return this.expand(e,-1)}intersect(e){return this===e?this:new lt(()=>Math.max(this.x,e.x),()=>Math.max(this.y,e.y),()=>Math.min(this.x2,e.x2)-Math.max(this.x,e.x),()=>Math.min(this.y2,e.y2)-Math.max(this.y,e.y))}isDefined(){return this.width>=0&&this.height>=0}flatten(){return new lt(ct(this.x),ct(this.y),ct(this.width),ct(this.height))}containsPoint(e,n){return e>=this.x&&e<this.x2&&n>=this.y&&n<this.y2}normalizePoint(e,n){return{x:(e-this.x)/this.width,y:(n-this.y)/this.height}}toString(){return`Rectangle: 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e=rn(t.orient);let n=t.ticks&&t.tickSize||0;return t.labels&&(n+=t.labelPadding,e=="x"?n+=t.labelFontSize:n+=30),t.title&&(n+=t.titlePadding+t.titleFontSize),n=Math.min(t.maxExtent||1/0,Math.max(t.minExtent||0,n)),n}function Bv(t,e,n,r=[]){const i=a=>25+60*bv(100,700,a);let o=me(t.tickCount)?t.tickCount:Math.round(n/i(n));o=sh(e,o,t.tickMinStep);const s=t.values?ah(e,t.values,o):Ow(e,o);if(bA(s,r,a=>a,a=>a.value))return r;{const a=Uw(e,o,t.format);return s.map(u=>({value:u,label:a(u)}))}}const Ih={values:null,minExtent:20,maxExtent:1/0,offset:0,domain:!0,domainWidth:1,domainColor:"gray",domainDash:null,domainDashOffset:0,domainCap:"square",ticks:!0,tickSize:5,tickWidth:1,tickColor:"gray",tickDash:null,tickDashOffset:0,tickCap:"square",tickCount:null,tickMinStep:null,labels:!0,labelAlign:"center",labelBaseline:"middle",labelPadding:4,labelFontSize:10,labelLimit:180,labelColor:"black",format:null,titleColor:"black",titleFont:"sans-serif",titleFontSize:10,titlePadding:3};function Fv(t,e){var a;const n=e.orient,r=t=="nominal"||t=="ordinal";let i="center",o="middle",s=(a=e.labelAngle)!=null?a:(n=="top"||n=="bottom")&&r?-90:0;switch(n){case"left":i="right";break;case"right":i="left";break;case"top":case"bottom":Math.abs(s)>30?(i=s>0==(n=="bottom")?"left":"right",o="middle"):o=n=="top"?"alphabetic":"top";break}return{labelAlign:i,labelAngle:s,labelBaseline:o}}function Th(t){const 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h={name:"ticks_and_labels",encoding:{[n]:{field:"value",type:"quantitative"}},layer:[]};return e.ticks&&h.layer.push(u()),e.labels&&h.layer.push(a()),h},l={[Fh[Ja(rn(e.orient))]]:e.extent,data:{dynamicCallbackSource:!0},layer:[]};return e.domain&&l.layer.push(s()),(e.ticks||e.labels)&&l.layer.push(f()),e.title&&l.layer.push(c()),l}const Mv={...Ih,chromTicks:!0,chromTickSize:18,chromTickWidth:1,chromTickColor:"#989898",chromTickDash:[4,2],chromTickDashOffset:1,chromLabels:!0,chromLabelFontSize:13,chromLabelFontWeight:"normal",chromLabelFontStyle:"normal",chromLabelColor:"black",chromLabelAlign:"left",chromLabelPadding:7};function Iv(t){const e={...t,extent:$a(t)},n=rn(e.orient),r=Ja(n),i=e.orient=="bottom"||e.orient=="left"?1:0,o=()=>({name:"chromosome_ticks",mark:{type:"rule",strokeDash:t.chromTickDash,strokeDashOffset:t.chromTickDashOffset,[r]:i,[r+"2"]:i-e.chromTickSize/e.extent*(i?1:-1),color:t.chromTickColor,size:e.chromTickWidth}}),s=()=>{let c;switch(e.orient){case"top":c={y:0,angle:0,paddingX:4,dy:-e.chromLabelPadding,viewportEdgeFadeWidthLeft:20,viewportEdgeFadeWidthRight:20,viewportEdgeFadeDistanceRight:-10,viewportEdgeFadeDistanceLeft:-20};break;case"bottom":c={y:1,angle:0,paddingX:4,dy:e.chromLabelPadding+e.chromLabelFontSize*.73,viewportEdgeFadeWidthLeft:20,viewportEdgeFadeWidthRight:20,viewportEdgeFadeDistanceRight:-10,viewportEdgeFadeDistanceLeft:-20};break;case"left":c={x:1,angle:-90,paddingY:4,dy:-e.chromLabelPadding,viewportEdgeFadeWidthBottom:20,viewportEdgeFadeWidthTop:20,viewportEdgeFadeDistanceBottom:-20,viewportEdgeFadeDistanceTop:-10};break;case"right":c={x:0,angle:90,align:"right",paddingY:4,dy:-e.chromLabelPadding};break;default:c={}}return{name:"chromosome_labels",mark:{type:"text",size:e.chromLabelFontSize,font:e.chromLabelFont,fontWeight:e.chromLabelFontWeight,fontStyle:e.chromLabelFontStyle,color:e.chromLabelColor,align:t.chromLabelAlign,baseline:"alphabetic",clip:!1,...c},encoding:{[n+"2"]:{field:"continuousEnd",type:"locus"},text:{field:"name"}}}};let a;switch(e.orient){case"bottom":case"top":a={};break;case"left":a={labelAngle:-90,labelAlign:"center",labelPadding:6};break;case"right":a={labelAngle:90,labelAlign:"center",labelPadding:6};break;default:a={}}const u=Th({...t,...a});if(t.chromTicks||t.chromLabels){const c={name:Bh,data:{dynamicCallbackSource:!0},encoding:{[n]:{field:"continuousStart",type:"locus",band:0}},layer:[]};if(t.chromTicks&&c.layer.push(o()),t.chromLabels){c.layer.push(s());let f;u.layer.filter(l=>l.name=="ticks_and_labels").forEach(l=>l.layer.filter(h=>h.name=="labels").forEach(h=>{f=h.mark})),f&&(e.orient=="top"||e.orient=="bottom"?(f.viewportEdgeFadeWidthLeft=30,f.viewportEdgeFadeDistanceLeft=40):(f.viewportEdgeFadeWidthBottom=30,f.viewportEdgeFadeDistanceBottom=40))}u.layer.push(c)}return u}const Ph={anchor:"middle",frame:"group",offset:10,orient:"top",align:void 0,angle:0,baseline:"alphabetic",dx:0,dy:0,color:void 0,font:void 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Cannot create a view!");return n.length==1}}function tu(t){return"mark"in t&&(Z(t.mark)||ke(t.mark))}function nu(t){return"layer"in t&&ke(t.layer)}function Rh(t){return t&&(tu(t)||nu(t))&&"aggregateSamples"in t}function Hv(t){return"import"in t}function ru(t){return"vconcat"in t&&Me(t.vconcat)}function Qv(t){return"hconcat"in t&&Me(t.hconcat)}function iu(t){return"concat"in t&&Me(t.concat)}const jv={point:Aw,rect:lw,rule:bw,link:Ew,text:Iw};class we extends Nn{constructor(e,n,r,i){super(e,n,r,i),this.spec=e;const o=jv[this.getMarkType()];if(o)this.mark=new o(this);else throw new Error(`No such mark: ${this.getMarkType()}`);this.sampleAggregateViews=[],this._initializeAggregateViews(),this.coords=void 0}*[Symbol.iterator](){for(const e of this.sampleAggregateViews)yield e}replaceChild(e,n){const r=this.sampleAggregateViews.indexOf(e);if(r>=0)this.sampleAggregateViews[r]=n;else throw new Error("Not my child view!")}render(e,n,r={}){!this.isVisible()||(this.coords=n,e.pushView(this,n),e.renderMark(this.mark,r),e.popView(this))}getMarkType(){return typeof this.spec.mark=="object"?this.spec.mark.type:this.spec.mark}resolve(e){var r;const n=this.mark.encoding;for(const[i,o]of Object.entries(n)){if(!Le(o))continue;let s=En((r=o.resolutionChannel)!=null?r:i);if(e=="axis"&&!Nr(s))continue;let a=this;for(;a.parent instanceof Nn&&["shared","excluded"].includes(a.parent.getConfiguredOrDefaultResolution(s,e))&&a.getConfiguredOrDefaultResolution(s,e)!="excluded";)a=a.parent;a.resolutions[e][s]||(a.resolutions[e][s]=e=="scale"?new gv(s):new yv(s)),Nr(i)?a.resolutions[e][s].pushUnitView(this,i):e=="scale"&&a.resolutions[e][s].pushUnitView(this,i)}}getAccessor(e){return this._cache("accessor/"+e,()=>{const n=this.mark.encoding;if(n&&n[e])return this.context.accessorFactory.createAccessor(n[e])})}getFacetAccessor(e){const n=this.getAccessor("sample");return n||super.getFacetAccessor(this)}getCollector(){return this.context.dataFlow.findCollectorByKey(this)}_validateDomainQuery(e){if(zr(e))throw new Error(`getDomain(${e}), must only be called for primary channels!`);const n=this.mark.encoding[e];if(!Le(n))throw new Error("The channel has no scale, cannot get domain!");return n}getConfiguredDomain(e){var i,o;const n=this._validateDomainQuery(e),r=n&&n.scale&&n.scale.domain;if(r){const s=this.getScaleResolution((i=n.resolutionChannel)!=null?i:e);return xh((o=n.type)!=null?o:"nominal",s.fromComplexInterval(r))}}extractDataDomain(e){var a;const r=(a=this._validateDomainQuery(e).type)!=null?a:"nominal",i=u=>{let c;const f=this.mark.encoding[u];if(f){const l=this.context.accessorFactory.createAccessor(f);if(l)if(c=xh(r),l.constant)c.extend(l({}));else{const h=this.getCollector();h!=null&&h.completed&&h.visitData(p=>c.extend(l(p)))}}return c};let o=i(e);const s=ca[e];if(s){const u=i(s);u&&o.extendAll(u)}return o}getZoomLevel(){const e=n=>{var r,i;return(i=(r=this.getScaleResolution(n))==null?void 0:r.getZoomLevel())!=null?i:1};return kr.map(e).reduce((n,r)=>n*r,1)}_initializeAggregateViews(){var e,n;if(Rh(this.spec))for(const r of this.spec.aggregateSamples){const i=(e=r.transform)!=null?e:[];i.length&&Cn(i).type!="collect"&&i.push({type:"collect"}),i.push({type:"mergeFacets"}),r.transform=i,r.encoding={...(n=r.encoding)!=null?n:{},sample:null};const o=this.context.createView(r,this,"summaryView");o.getFacetFields=s=>{},this.sampleAggregateViews.push(o)}}propagateInteractionEvent(e){e.target=this}getDefaultResolution(e,n){return e=="x"?"shared":"independent"}}function*ou(t,e=[]){for(const[n,r]of t.entries())if(r instanceof Map)for(const i of ou(r,[...e,n]))yield i;else yield[[...e,n],r]}class su extends J{constructor(e){super(),this.params=e!=null?e:{type:"collect"},this.observers=[],this.facetBatches=void 0,this._init()}_init(){this._data=[],this.facetBatches=new Pt([],JSON.stringify),this.facetBatches.set(void 0,this._data)}reset(){super.reset(),this._init()}handle(e){this._data.push(e)}beginBatch(e){pw(e)&&(this._data=[],this.facetBatches.set(Ke(e.facetId),this._data))}complete(){var i,o;const e=(i=this.params)==null?void 0:i.sort,n=e?yu(e.field,e.order):void 0,r=s=>{n&&s.sort(n)};if((o=this.params.groupby)!=null&&o.length){if(this.facetBatches.size>1)throw new Error("TODO: Support faceted data!");const s=this.params.groupby.map(u=>H(u)),a=di(this._data,...s);this.facetBatches.clear();for(const[u,c]of ou(a))this.facetBatches.set(u,c)}for(const s of this.facetBatches.values())r(s);if(this.children.length)for(const[s,a]of this.facetBatches.entries()){if(s){const u={type:"facet",facetId:s};for(const c of this.children)c.beginBatch(u)}for(const u of a)this._propagate(u)}super.complete();for(const s of this.observers)s(this)}getData(){switch(this._checkStatus(),this.facetBatches.size){case 0:return[];case 1:return[...this.facetBatches.values()][0];default:{const e=this.facetBatches;return{[Symbol.iterator]:function*(){for(const r of e.values())for(let i=0;i<r.length;i++)yield r[i]}}}}}visitData(e){this._checkStatus();for(const n of this.facetBatches.values())for(let r=0;r<n.length;r++)e(n[r])}getItemCount(){let e=0;for(const n of this.facetBatches.values())e+=n.length;return e}_checkStatus(){if(!this.completed)throw new Error("Data propagation is not completed! No data are available.")}}class Bo{constructor(){this.ids=[],this.values=[],this.length=0}clear(){this.length=0}push(e,n){let r=this.length++;for(;r>0;){const i=r-1>>1,o=this.values[i];if(n>=o)break;this.ids[r]=this.ids[i],this.values[r]=o,r=i}this.ids[r]=e,this.values[r]=n}pop(){if(this.length===0)return;const e=this.ids[0];if(this.length--,this.length>0){const n=this.ids[0]=this.ids[this.length],r=this.values[0]=this.values[this.length],i=this.length>>1;let o=0;for(;o<i;){let s=(o<<1)+1;const a=s+1;let u=this.ids[s],c=this.values[s];const f=this.values[a];if(a<this.length&&f<c&&(s=a,u=this.ids[a],c=f),c>=r)break;this.ids[o]=u,this.values[o]=c,o=s}this.ids[o]=n,this.values[o]=r}return e}peek(){if(this.length!==0)return this.ids[0]}peekValue(){if(this.length!==0)return this.values[0]}shrink(){this.ids.length=this.values.length=this.length}}class Vv extends J{get behavior(){return ut}constructor(e){super(),this.params=e,this.startAccessor=H(e.start),this.endAccessor=H(e.end),this.chromAccessor=e.chrom?H(e.chrom):n=>{},this.weightAccessor=e.weight?H(e.weight):n=>1,this.as={coverage:e.as||"coverage",start:e.asStart||e.start,end:e.asEnd||e.end,chrom:e.asChrom||e.chrom},this.createSegment=new Function("start","end","coverage","chrom","return {"+Object.entries(this.as).filter(([n,r])=>r).map(([n,r])=>`${JSON.stringify(r)}: ${n}`).join(", ")+"};"),this.ends=new Bo}reset(){super.reset(),this.initialize()}initialize(){const e=this.as.coverage,n=this.as.end,r=this.as.chrom,i=this.startAccessor,o=this.endAccessor,s=this.chromAccessor,a=this.weightAccessor;let u,c,f,l=0,h;const p=this.ends;p.clear();const d=(A,m,b)=>{if(A==m)return;let y=!1;u&&(u[e]===b?(u[n]=m,y=!0):u[e]!=0&&this._propagate(u)),y||(u=this.createSegment(A,m,b,f))},g=()=>{let A;for(;(A=p.peekValue())!==void 0;)d(h,A,l),h=A,l-=p.pop();h=void 0,u&&(this._propagate(u),u=void 0)};this.handle=A=>{const m=i(A);let b;for(;(b=p.peekValue())!==void 0&&b<m;)d(h,b,l),h=b,l-=p.pop();if(r){let w=s(A);w!==c&&(g(),f=w,c=f)}h!==void 0&&d(h,m,l),h=m;const y=a(A);l+=y,p.push(y,o(A))},this.complete=()=>{g(),super.complete()}}}function Yv(t,e,n=0,r=t.length){const i=new Bo,o=r-n;let s;for(s=0;s<e&&s<o;s++)i.push(s,t[n+s]);for(;s<o;s++){const c=t[n+s];c>=i.peekValue()&&(i.push(s,c),i.pop())}const a=[];let u;for(;(u=i.pop())!==void 0;)a.push(n+u);return a.reverse()}class Wv{constructor(e,n=-1/0,r=1/0){this.maxSize=e,this.lowerLimit=n,this.upperLimit=r;const i=this.maxSize*2+1;this.lowerLimits=new Float64Array(i),this.upperLimits=new Float64Array(i),this.lowerChildren=new Int32Array(i),this.upperChildren=new Int32Array(i),this.reset()}reset(){this.lowerLimits.fill(0),this.upperLimits.fill(0),this.lowerChildren.fill(0),this.upperChildren.fill(0),this.n=1,this.lowerLimits[0]=this.lowerLimit,this.upperLimits[0]=this.upperLimit}_findSlot(e,n,r=0){if(e>=this.lowerLimits[r]&&n<=this.upperLimits[r]){const i=this.lowerChildren[r];if(i){const o=this._findSlot(e,n,i);return o>=0?o:this._findSlot(e,n,this.upperChildren[r])}else return r}else return-1}reserve(e,n){if(n-e<=0)throw new Error("Cannot reserve an empty or negative-size slot!");if(this.n+1>this.lowerLimits.length)return!1;const r=this._findSlot(e,n);if(r<0)return!1;const i=this.n++,o=this.n++;return this.lowerLimits[i]=this.lowerLimits[r],this.upperLimits[i]=e,this.lowerLimits[o]=n,this.upperLimits[o]=this.upperLimits[r],this.lowerChildren[r]=i,this.upperChildren[r]=o,!0}}class Xv extends J{constructor(e,n){var i,o;if(super(),this.params=e,this._data=[],this.channel=(i=e.channel)!=null?i:"x",!["x","y"].includes(this.channel))throw new Error("Invalid channel: 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0:s[this.channel=="x"?"width":"height"];if(!n)return;for(const a of this.reservationMaps.values())a.reset();const r=e.domain(),i=70,o=Yv(this._scores,i,this.posBisector.left(this._data,r[0]),this.posBisector.right(this._data,r[1]));for(const a of o){const u=this._data[a],c=e(this.posAccessor(u))*n,f=this.widthAccessor(u)/2+this.padding;this.reservationMaps.get(this.laneAccessor(u)).reserve(c-f,c+f)&&this._propagate(u)}super.complete()}reset(){super.reset(),this._data=[],this.groups=new Map}handle(e){this._data.push(e)}}class Zv extends J{constructor(e){super(),this.params=e,this.predicate=void 0}initialize(){this.predicate=sa(this.params.expr,this.getGlobalObject())}handle(e){this.predicate(e)&&this._propagate(e)}}const Kv="0".charCodeAt(0);function*qv(t,e=","){const n=e.charCodeAt(0);let r=0;for(let i=0;i<t.length;i++){const o=t.charCodeAt(i);o==n?(yield r,r=0):r=r*10+o-Kv}yield r}class Jv extends J{get behavior(){return ut}constructor(e){var s,a;super();const n=H((s=e.exons)!=null?s:"exons"),r=H((a=e.start)!=null?a:"start"),[i,o]=e.as||["exonStart","exonEnd"];this.handle=u=>{let c=r(u),f=c,l=!0;const h=n(u);for(const p of qv(h)){if(l)f=c+p;else{c=f+p;const d=Object.assign({},u);d[i]=f,d[o]=c,this._propagate(d)}l=!l}}}}class _v extends J{get behavior(){return ut}constructor(e){super();const n=Ke(e.field).map(o=>H(o)),r=Ke(e.separator),i=Ke(e.as||e.field);if(n.length!==r.length||n.length!==i.length)throw new Error(`Lengths of "separator" (${r.length}), "fields" (${n.length}), and "as" (${i.length}) do not match!`);this.handle=o=>{if(n.some(u=>!u(o)))return;const s=n.map((u,c)=>u(o).split(r[c]));$v(s,o);const a=s[0].length;for(let u=0;u<a;u++){const c=Object.assign({},o);for(let f=0;f<n.length;f++)c[i[f]]=s[f][u];this._propagate(c)}}}}function $v(t,e){const n=t.map(r=>r.length);if(!n.every(r=>r==n[0]))throw new Error("Mismatching number of elements in the fields to be split: "+JSON.stringify(e))}class eC extends J{get behavior(){return Ft}constructor(e){super(),this.params=e,this.as=e.as,this.fn=void 0}initialize(){this.fn=sa(this.params.expr,this.getGlobalObject())}handle(e){e[this.as]=this.fn(e),this._propagate(e)}}class kh extends J{get behavior(){return Ft}constructor(e,n){var d;super();const r=(d=e.channel)!=null?d:"x";if(!["x","y"].includes(r))throw new Error("Invalid channel: "+r);const i=n.getScaleResolution(r).getGenome();if(!i)throw new Error("LinearizeGenomicCoordinate transform requires a locus scale!");const o=H(e.chrom),s=Ke(e.pos).map(g=>H(g)),a=Ke(e.as);if(s.length!=a.length)throw new Error('The number of "pos" and "as" elements must be equal!');const u=Ke(e.offset);let c;if(u.length==0)c=new Array(s.length).fill(0);else if(u.length==1)c=new Array(s.length).fill(u[0]);else if(u.length==s.length)c=u;else throw new Error(`Invalid "offset" parameter: ${JSON.stringify(e.offset)}!`);const f=new Function("datum","chromOffset","posAccessors",a.map((g,A)=>`datum[${JSON.stringify(g)}] = chromOffset + +posAccessors[${A}](datum) - ${c[A]};`).join(`
+ */const Yw="locus",Ww="index";var Xw=5;function Zw(t){const e=t.type;return!t.bins&&(e===bn||e===wr||e===vr)}function uh(t){return Pe(t)&&![Ze,Ww,Yw].includes(t)}function ch(t){return t||{warn:(e,...n)=>console.warn(e,...n)}}var Kw=fi(["set","modified","clear","type","scheme","schemeExtent","schemeCount","domain","domainMin","domainMid","domainMax","domainRaw","domainImplicit","nice","zero","bins","range","rangeStep","round","reverse","interpolate","interpolateGamma","zoom","fp64","name"]);function lh(t,e,n){n=ch(n);for(const r in t)if(!Kw[r]){if(r==="padding"&&uh(e.type))continue;ge(e[r])?e[r](t[r]):n.warn("Unsupported scale property: "+r)}rv(e,t,nv(e,t,$w(e,t,n)))}function qw(t,e){const n=Jw(t),r=O(n);if(!r)throw new Error("Unknown scale type: "+n);const i=r();return lh(t,i,e),i}function Jw(t){var e=t.type,n="",r;return e===Ze?Ze+"-"+bn:(_w(t)&&(r=t.rawDomain?t.rawDomain.length:t.domain?t.domain.length+ +(t.domainMid!=null):0,n=r===2?Ze+"-":r===3?wn+"-":""),(n+e||bn).toLowerCase())}function _w(t){const e=t.type;return Pe(e)&&e!==Vl&&e!==Yl&&(t.scheme||t.range&&t.range.length&&t.range.every(Z))}function $w(t,e,n){if(!t.domain)return 0;n=ch(n);var r=ev(t,e.domainRaw,n);if(r>-1)return r;var i=e.domain,o=t.type,s=e.zero||e.zero===void 0&&Zw(t),a,u;return i?(uh(o)&&e.padding&&i[0]!==Ne(i)&&(i=tv(o,i,e.range,e.padding,e.exponent,e.constant)),(s||e.domainMin!=null||e.domainMax!=null||e.domainMid!=null)&&(a=(i=i.slice()).length-1||1,s&&(i[0]>0&&(i[0]=0),i[a]<0&&(i[a]=0)),e.domainMin!=null&&(i[0]=e.domainMin),e.domainMax!=null&&(i[a]=e.domainMax),e.domainMid!=null&&(u=e.domainMid,(u<i[0]||u>i[a])&&n.warn("Scale domainMid exceeds domain min or max.",u),i.splice(a,0,u))),t.domain(fh(o,i,n)),o===Xs&&t.unknown(e.domainImplicit?ps:void 0),e.nice&&t.nice&&t.nice(e.nice!==!0&&sh(t,e.nice)||null),i.length):0}function ev(t,e,n){return e?(t.domain(fh(t.type,e,n)),e.length):-1}function tv(t,e,n,r,i,o){var s=Math.abs(Ne(n)-n[0]),a=s/(s-2*r),u=t===bt?xu(e,null,a):t===vr?Lo(e,null,a,.5):t===wr?Lo(e,null,a,i||1):t===Hi?hd(e,null,a,o||1):Au(e,null,a);return e=e.slice(),e[0]=u[0],e[e.length-1]=u[1],e}function fh(t,e,n){if(_l(t)){var r=Math.abs(e.reduce(function(i,o){return i+(o<0?-1:o>0?1:0)},0));r!==e.length&&n.warn("Log scale domain includes zero: "+li(e))}return e}function nv(t,e,n){let r=e.bins;if(r&&!Me(r)){const i=(r.start==null||r.stop==null)&&t.domain(),o=r.start==null?i[0]:r.start,s=r.stop==null?Ne(i):r.stop,a=r.step;a||X("Scale bins parameter missing step property."),r=Kn(o,s+a,a)}return r?t.bins=r:t.bins&&delete t.bins,t.type===Ks&&(r?!e.domain&&!e.domainRaw&&(t.domain(r),n=r.length):t.bins=t.domain()),n}function rv(t,e,n){var r=t.type,i=e.round||!1,o=e.range;if(e.rangeStep!=null)o=iv(r,e,n);else if(e.scheme&&(o=ov(r,e,n),ge(o))){if(t.interpolator)return t.interpolator(o);X(`Scale type ${r} does not support interpolating color schemes.`)}if(o&&ji(r))return t.interpolator(Vi(Za(o,e.reverse),e.interpolate,e.interpolateGamma));o&&e.interpolate&&t.interpolate?t.interpolate($l(e.interpolate,e.interpolateGamma)):ge(t.round)?t.round(i):ge(t.rangeRound)&&t.interpolate(i?yr:xt),o&&t.range(Za(o,e.reverse))}function iv(t,e,n){t!==Zl&&t!==Zs&&X("Only band and point scales support rangeStep.");var r=(e.paddingOuter!=null?e.paddingOuter:e.padding)||0,i=t===Zs?1:(e.paddingInner!=null?e.paddingInner:e.padding)||0;return[0,e.rangeStep*Ys(n,i,r)]}function ov(t,e,n){var r=e.schemeExtent,i,o;return Me(e.scheme)?o=Vi(e.scheme,e.interpolate,e.interpolateGamma):(i=e.scheme.toLowerCase(),o=Js(i),o||X(`Unrecognized scheme name: ${e.scheme}`)),n=t===Xl?n+1:t===Ks?n-1:t===Ws||t===Wl?+e.schemeCount||Xw:n,ji(t)?hh(o,r,e.reverse):ge(o)?gA(hh(o,r),n):t===Xs?o:o.slice(0,n)}function hh(t,e,n){return ge(t)&&(e||n)?pA(t,Za(e||[0,1],n)):t}function Za(t,e){return e?t.slice().reverse():t}const dh=se(",d");function sv(t,e){return t.chrom+":"+dh(Math.floor(t.pos+1))+"-"+(t.chrom!=e.chrom?e.chrom+":":"")+dh(Math.ceil(e.pos))}const av="https://genomespy.app/data/genomes/";class uv{constructor(e){if(this.config=e,!this.config.contigs&&typeof this.config.name!="string")throw new Error("No name has been defined for the genome assembly!");this.chromosomes=[],this.cumulativeChromPositions=new Map,this.chromosomesByName=new Map,this.startByIndex=[],this.totalSize=0,this.config.contigs&&this.setChromSizes(this.config.contigs)}get name(){return this.config.name}async load(e){if(!this.config.contigs){this.config.baseUrl?this.baseUrl=/^http(s)?/.test(this.config.baseUrl)?this.config.baseUrl:e+"/"+this.config.baseUrl:this.baseUrl=av;try{this.setChromSizes(cv(await Di({baseURL:this.baseUrl}).load(`${this.config.name}/${this.name}.chrom.sizes`)))}catch(n){throw new Error(`Could not load chrom sizes: ${n.message}`)}}}setChromSizes(e){let n=0;this.startByIndex=[0];for(let r=0;r<e.length;r++){this.startByIndex.push(n);const i=e[r].size,o={...e[r],continuousStart:n,continuousEnd:n+i,continuousInterval:[n,n+i],index:r,number:r+1,odd:!(r&1)};this.chromosomes.push(o);const s=o.name.replace(/^chr/i,"");for(const a of["chr"+s,"CHR"+s,"Chr"+s,o.number,""+o.number,s,o.name])this.cumulativeChromPositions.set(a,n),this.chromosomesByName.set(a,o);n+=o.size}this.totalSize=n}getExtent(){return[0,this.totalSize]}toContinuous(e,n){let r=this.cumulativeChromPositions.get(e);if(r===void 0)throw new Error("Unknown chromosome/contig: "+e);return r+ +n}toChromosome(e){if(e>=this.totalSize)return;e=Math.floor(e);const n=an(this.startByIndex,e)-1;if(n>0&&n<=this.chromosomes.length)return this.chromosomes[n-1]}toChromosomal(e){const n=this.toChromosome(e);if(!!n)return{chrom:n.name,pos:Math.floor(e)-n.continuousStart}}getChromosome(e){return this.chromosomesByName.get(e)}formatInterval(e){return sv(...this.toChromosomalInterval(e))}toChromosomalInterval(e){const n=this.toChromosomal(e[0]+.5),r=this.toChromosomal(e[1]-.5);return r.pos+=1,[n,r]}toContinuousInterval(e){var i,o,s;let[n,r]=e;return r||(r=n),[this.toContinuous(n.chrom,(i=n.pos)!=null?i:0),this.toContinuous(r.chrom,(s=r.pos)!=null?s:(o=this.chromosomesByName.get(r.chrom))==null?void 0:o.size)]}parseInterval(e){const n=e.match(/^(chr[0-9A-Z]+)(?::([0-9,]+)(?:-(?:(chr[0-9A-Z]+):)?([0-9,]+))?)?$/);if(n){const r=n[1];if(n.slice(2).every(a=>a===void 0)){const a=this.getChromosome(r);return a?[a.continuousStart,a.continuousEnd]:void 0}const i=n[3]||r,o=parseInt(n[2].replace(/,/g,"")),s=n[4]!==void 0?parseInt(n[4].replace(/,/g,"")):o;return[this.toContinuous(r,o-1),this.toContinuous(i,s)]}}}function cv(t){return Td(t).filter(e=>/^chr[0-9A-Z]+$/.test(e[0])).map(([e,n])=>({name:e,size:parseInt(n)}))}function ph(t){return ke(t)&&"chrom"in t}function lv(t){return t.every(ph)}class qr extends Array{constructor(){super(),this.type=void 0}extend(e){return this}extendAll(e){if(e instanceof qr&&e.type!=this.type)throw new Error(`Cannot combine different types of domains: ${this.type} and ${e.type}`);for(const n of e)this.extend(n);return this}extendAllWithAccessor(e,n){for(const r of e)this.extend(n(r));return this}}class Ka extends qr{constructor(){super(),this.type="quantitative"}extend(e){return e==null||Number.isNaN(e)?this:(e=+e,this.length?e<this[0]?this[0]=e:e>this[1]&&(this[1]=e):(this.push(e),this.push(e)),this)}}class gh extends qr{constructor(){super(),this.type="ordinal",this.uniqueValues=new Set}extend(e){return e==null||Number.isNaN(e)?this:(this.uniqueValues.has(e)||(this.uniqueValues.add(e),this.push(e)),this)}}class mh extends gh{constructor(){super(),this.type="nominal"}}class fv extends qr{constructor(e){super();let n=0;for(let r=1;r<e.length;r++)n+=Math.sign(e[r]-e[r-1]);if(Math.abs(n)!=e.length-1)throw new Error("Piecewise domain must be strictly increasing or decreasing: "+JSON.stringify(e));e.forEach(r=>this.push(r))}extend(e){if(this.includes(e))return this;throw new Error("Piecewise domains are immutable and cannot be unioned!")}}const Ah={quantitative:Ka,index:Ka,locus:Ka,nominal:mh,ordinal:gh};function xh(t,e){if(t=="quantitative"&&hv(e)){const n=new fv(e);return n.type=t,n}else if(Ah[t]){const n=new Ah[t];return n.type=t,e&&n.extendAll(e),n}throw new Error("Unknown type: "+t)}function hv(t){return t&&t.length>0&&t.length!=2&&t.every(e=>typeof e=="number")}function dv(t){return((t*=2)<=1?t*t:--t*(2-t)+1)/2}const yh="quantitative",bh="ordinal",wh="nominal",vh="locus",pv="index";class gv{constructor(e){this.channel=e,this.members=[],this.type=null,this._zoomExtent=void 0,this._domainListeners=new Set,this.name=void 0,this._scale=void 0}addEventListener(e,n){if(e!="domain")throw new Error("Unsupported event type: "+e);this._domainListeners.add(n)}removeEventListener(e,n){if(e!="domain")throw new Error("Unsupported event type: "+e);this._domainListeners.delete(n)}_notifyDomainListeners(){for(const e of this._domainListeners.values())e({type:"domain",scaleResolution:this})}pushUnitView(e,n){var s;const r=aa(e,n),i=r.type,o=(s=r==null?void 0:r.scale)==null?void 0:s.name;if(o){if(this.name!==void 0&&o!=this.name)throw new Error(`Shared scales have conflicting names: "${o}" vs. "${this.name}"!`);this.name=o}if(!this.type)this.type=i;else if(i!==this.type&&!zr(n))throw new Error(`Can not use shared scale for different data types: ${this.type} vs. ${i}. Use "resolve: independent" for channel ${this.channel}`);this.members.push({view:e,channel:n})}isExplicitDomain(){return!!this.getConfiguredDomain()}_getMergedScaleProps(){return kn(this,"mergedScaleProps",()=>{const e=this.members.map(n=>aa(n.view,n.channel).scale).filter(n=>n!==void 0);return So(e,"scale",["domain"])})}getScaleProps(){return kn(this,"scaleProps",()=>{var i,o;const e=this._getMergedScaleProps();if(e===null||e.type=="null")return{type:"null"};const n={...this._getDefaultScaleProperties(this.type),...e};n.type||(n.type=mv(this.channel,this.type));const r=this.getInitialDomain();return r&&r.length>0?n.domain=r:Wt(n.type)&&(n.domain=new mh),!n.domain&&n.domainMid!==void 0&&(n.domain=[(i=n.domainMin)!=null?i:0,(o=n.domainMax)!=null?o:1]),this.channel=="y"&&Wt(n.type)&&n.reverse==null&&(n.reverse=!0),n.range&&n.scheme&&delete n.scheme,!("zoom"in n)&&["index","locus"].includes(n.type)&&(n.zoom=!0),Av(n,this.channel),n})}getInitialDomain(){var e;return(e=this.getConfiguredDomain())!=null?e:this.type==vh?this.getGenome().getExtent():this.getDataDomain()}getConfiguredDomain(){return this._reduceDomains(e=>zr(e.channel)?void 0:e.view.getConfiguredDomain(e.channel))}getDataDomain(){return this._reduceDomains(e=>zr(e.channel)?void 0:e.view.extractDataDomain(e.channel))}reconfigure(){if(this._scale&&this._scale.type!="null"){V0(this,"scaleProps");const e=this.getScaleProps();lh(e,this._scale),Pe(this._scale.type)&&(this._zoomExtent=this._getZoomExtent())}}getScale(){if(this._scale)return this._scale;const e=this.getScaleProps(),n=qw(e);return this._scale=n,nm(n)&&n.genome(this.getGenome()),Pe(n.type)&&(this._zoomExtent=this._getZoomExtent()),n}getDomain(){return this.getScale().domain()}getComplexDomain(){var e,n;return(n=(e=this.getGenome())==null?void 0:e.toChromosomalInterval(this.getDomain()))!=null?n:this.getDomain()}isZoomed(){return this.isZoomable()&&rf(this.getInitialDomain(),this.getDomain())}isZoomable(){if(!yf(this.channel))return!1;const e=this.getScale().type;return["linear","locus","index","log","pow","sqrt"].includes(e)?!!this.getScaleProps().zoom:!1}zoom(e,n,r){if(!this.isZoomable())return!1;const i=this.getScale(),o=i.domain();let s=[...o],a=i.invert(n);switch(this.getScaleProps().reverse&&(r=-r),"align"in i&&(a+=i.align()),i.type){case"linear":case"index":case"locus":s=cd(s,r||0),s=Au(s,a,e);break;case"log":s=ld(s,r||0),s=xu(s,a,e);break;case"pow":case"sqrt":{const u=i;s=fd(s,r||0,u.exponent()),s=Lo(s,a,e,u.exponent());break}default:throw new Error("Zooming is not implemented for: "+i.type)}return this._zoomExtent&&(s=dd(s,this._zoomExtent[0],this._zoomExtent[1])),[0,1].some(u=>s[u]!=o[u])?(i.domain(s),this._notifyDomainListeners(),!0):!1}async zoomTo(e,n=!1){var a;if(ui(n)&&(n=n?700:0),!this.isZoomable())throw new Error("Not a zoomable scale!");const r=this.fromComplexInterval(e),i=(a=this.members[0])==null?void 0:a.view.context.animator,o=this.getScale(),s=o.domain();if(n>0&&s.length==2){const u=s[1]-s[0],c=s[0]+u/2,f=r[1]-r[0],l=r[0]+f/2,h=yl([c,0,u],[l,0,f]).rho(.7);await i.transition({duration:n/1e3*h.duration,easingFunction:dv,onUpdate:p=>{const[d,,g]=h(p);o.domain([d-g/2,d+g/2]),this._notifyDomainListeners()}}),o.domain(r),this._notifyDomainListeners()}else o.domain(r),i==null||i.requestRender(),this._notifyDomainListeners()}resetZoom(){if(!this.isZoomable())throw new Error("Not a zoomable scale!");const e=this.getDomain(),n=this.getInitialDomain();return[0,1].some(r=>n[r]!=e[r])?(this._scale.domain(n),this._notifyDomainListeners(),!0):!1}getZoomLevel(){return this.isZoomable()?ci(this._zoomExtent)/ci(this.getScale().domain()):1}_getZoomExtent(){const e=this.getScaleProps(),n=e.zoom;if(xv(n)&&Me(n.extent))return this.fromComplexInterval(n.extent);if(n)return e.type=="locus"?this.getGenome().getExtent():this._scale.domain()}_getDefaultScaleProperties(e){const n=this.channel,r={};return this.isExplicitDomain()&&(r.zero=!1),Nr(n)?r.nice=!this.isExplicitDomain():qt(n)?r.scheme=e==wh?"tableau10":e==bh?"blues":"viridis":Ji(n)?r.range=wf(n):n=="size"?r.range=[0,400]:n=="angle"&&(r.range=[0,360]),r}getGenome(){var n;if(this.type!=="locus")return;const e=(n=this.members[0].view.context.genomeStore)==null?void 0:n.getGenome();if(!e)throw new Error("No genome has been defined!");return e}invertToComplex(e){const n=this.getScale();if("invert"in n){const r=n.invert(e);return this.toComplex(r)}else throw new Error("The scale does not support inverting!")}toComplex(e){const n=this.getGenome();return n?n.toChromosomal(e):e}fromComplex(e){return ph(e)?this.getGenome().toContinuous(e.chrom,e.pos):e}fromComplexInterval(e){return this.type==="locus"&&lv(e)?this.getGenome().toContinuousInterval(e):e}_getViewPaths(){return this.members.map(e=>e.view.getPathString()).join(", ")}_reduceDomains(e){const n=this.members.map(e).filter(r=>!!r);if(n.length)return n.reduce((r,i)=>r.extendAll(i))}}function mv(t,e){if(e==pv||e==vh){if(yf(t))return e;throw new Error(`${t} does not support ${e} data type. Only positional channels do.`)}const n={x:["band","band","linear"],y:["band","band","linear"],size:[void 0,"point","linear"],opacity:[void 0,"point","linear"],fillOpacity:[void 0,"point","linear"],strokeOpacity:[void 0,"point","linear"],color:["ordinal","ordinal","linear"],fill:["ordinal","ordinal","linear"],stroke:["ordinal","ordinal","linear"],strokeWidth:[void 0,void 0,"linear"],shape:["ordinal","ordinal",void 0],dx:[void 0,void 0,"null"],dy:[void 0,void 0,"null"],angle:[void 0,void 0,"linear"]},i=["uniqueId","facetIndex","semanticScore","search","text","sample"].includes(t)?"null":n[t]?n[t][[wh,bh,yh].indexOf(e)]:e==yh?"linear":"ordinal";if(i===void 0)throw new Error(`Channel "${t}" is not compatible with "${e}" data type. Use of a proper scale may be needed.`);return i}function Av(t,e){Nr(e)&&t.type!=="ordinal"&&(t.range=[0,1]),e=="opacity"&&Pe(t.type)&&(t.clamp=!0)}function xv(t){return ke(t)}function qa(...t){for(const e of t)if(e!==void 0)return e}class yv{constructor(e){this.channel=e,this.members=[]}get scaleResolution(){var e;return(e=Cn(this.members))==null?void 0:e.view.getScaleResolution(this.channel)}pushUnitView(e,n){const r=e.getScaleResolution(this.channel);if(!r)throw new Error("Cannot find a scale resolution!");if(this.scaleResolution&&r!==this.scaleResolution)throw new Error("Shared axes must have a shared scale!");this.members.push({view:e,channel:n})}getAxisProps(){return kn(this,"axisProps",()=>{const e=this.members.map(n=>{const r=n.view.mark.encoding[n.channel];return"axis"in r&&r.axis});return e.length>0&&e.some(n=>n===null)?null:So(e.filter(n=>n!==void 0),"axis",["title"])})}getTitle(){const e=o=>{var a;const s=aa(o.view,o.channel);if(!Ue(s))return{member:o,explicitTitle:qa((a=s.axis)==null?void 0:a.title,s.title),implicitTitle:qa(Lr(s)?s.field:void 0,ua(s)?s.expr:void 0)}},n=this.members.map(e),r=n.filter(o=>{var s;if(zr(o.member.channel)&&!o.explicitTitle){const a=En(o.member.channel);return((s=n.find(u=>u.member.view==o.member.view&&u.member.channel==a))==null?void 0:s.explicitTitle)===void 0}return!0}),i=new Set(r.map(o=>qa(o.explicitTitle,o.implicitTitle)).filter(Z));return i.size?[...i].join(", "):null}}class Ch extends ih{constructor(e,n,r,i){super(e,n,r,i),this.spec=e}}class nn extends Nn{constructor(e,n,r,i){super(e,n,r,i),this.spec=e,this.children=(e.layer||[]).map((o,s)=>{if(nu(o)||tu(o))return n.createView(o,this,"layer"+s);throw new Error("LayerView accepts only unit or layer specs as children!")})}*[Symbol.iterator](){for(const e of this.children)yield e}render(e,n,r={}){if(!!this.isVisible()){e.pushView(this,n);for(const i of this.children)i.render(e,n,r);e.popView(this)}}propagateInteractionEvent(e){this.handleInteractionEvent(void 0,e,!0),this.children.length&&this.children.at(-1).propagateInteractionEvent(e),!e.stopped&&this.handleInteractionEvent(void 0,e,!1)}}class Eh{constructor(e,n){this.n=e,this.maxCols=n!=null?n:1/0}get nRows(){return this.maxCols==1/0?1:Math.ceil(this.n/this.maxCols)}get nCols(){return Math.min(this.n,this.maxCols)}get rowIndices(){const e=[],n=this.nCols,r=this.nRows;for(let i=0;i<r;i++){const o=[];e.push(o);for(let s=0;s<n;s++){const a=i*n+s;a<this.n&&o.push(a)}}return e}get colIndices(){const e=[],n=this.nCols,r=this.nRows;for(let i=0;i<n;i++){const o=[];e.push(o);for(let s=0;s<r;s++){const a=s*n+i;a<this.n&&o.push(a)}}return e}getCellIndex(e,n){let r=0;if(this.maxCols==1/0)r=n==0?e:void 0;else{if(e>=this.maxCols)return;r=n*this.nCols+e}return r<this.n?r:void 0}getCellCoords(e){if(!(e<0||e>=this.n))return[e%this.nCols,Math.floor(e/this.nCols)]}}function ct(t){return()=>t}const 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Cannot create a view!");return n.length==1}}function tu(t){return"mark"in t&&(Z(t.mark)||ke(t.mark))}function nu(t){return"layer"in t&&ke(t.layer)}function Rh(t){return t&&(tu(t)||nu(t))&&"aggregateSamples"in t}function Hv(t){return"import"in t}function ru(t){return"vconcat"in t&&Me(t.vconcat)}function Qv(t){return"hconcat"in t&&Me(t.hconcat)}function iu(t){return"concat"in t&&Me(t.concat)}const jv={point:Aw,rect:lw,rule:bw,link:Ew,text:Iw};class we extends Nn{constructor(e,n,r,i){super(e,n,r,i),this.spec=e;const o=jv[this.getMarkType()];if(o)this.mark=new o(this);else throw new Error(`No such mark: ${this.getMarkType()}`);this.sampleAggregateViews=[],this._initializeAggregateViews(),this.coords=void 0}*[Symbol.iterator](){for(const e of this.sampleAggregateViews)yield e}replaceChild(e,n){const r=this.sampleAggregateViews.indexOf(e);if(r>=0)this.sampleAggregateViews[r]=n;else throw new Error("Not my child view!")}render(e,n,r={}){!this.isVisible()||(this.coords=n,e.pushView(this,n),e.renderMark(this.mark,r),e.popView(this))}getMarkType(){return typeof this.spec.mark=="object"?this.spec.mark.type:this.spec.mark}resolve(e){var r;const n=this.mark.encoding;for(const[i,o]of Object.entries(n)){if(!Le(o))continue;let s=En((r=o.resolutionChannel)!=null?r:i);if(e=="axis"&&!Nr(s))continue;let a=this;for(;a.parent instanceof Nn&&["shared","excluded"].includes(a.parent.getConfiguredOrDefaultResolution(s,e))&&a.getConfiguredOrDefaultResolution(s,e)!="excluded";)a=a.parent;a.resolutions[e][s]||(a.resolutions[e][s]=e=="scale"?new gv(s):new yv(s)),Nr(i)?a.resolutions[e][s].pushUnitView(this,i):e=="scale"&&a.resolutions[e][s].pushUnitView(this,i)}}getAccessor(e){return this._cache("accessor/"+e,()=>{const n=this.mark.encoding;if(n&&n[e])return this.context.accessorFactory.createAccessor(n[e])})}getFacetAccessor(e){const n=this.getAccessor("sample");return n||super.getFacetAccessor(this)}getCollector(){return this.context.dataFlow.findCollectorByKey(this)}_validateDomainQuery(e){if(zr(e))throw new Error(`getDomain(${e}), must only be called for primary channels!`);const n=this.mark.encoding[e];if(!Le(n))throw new Error("The channel has no scale, cannot get domain!");return n}getConfiguredDomain(e){var i,o;const n=this._validateDomainQuery(e),r=n&&n.scale&&n.scale.domain;if(r){const s=this.getScaleResolution((i=n.resolutionChannel)!=null?i:e);return xh((o=n.type)!=null?o:"nominal",s.fromComplexInterval(r))}}extractDataDomain(e){var a;const r=(a=this._validateDomainQuery(e).type)!=null?a:"nominal",i=u=>{let c;const f=this.mark.encoding[u];if(f){const l=this.context.accessorFactory.createAccessor(f);if(l)if(c=xh(r),l.constant)c.extend(l({}));else{const h=this.getCollector();h!=null&&h.completed&&h.visitData(p=>c.extend(l(p)))}}return c};let o=i(e);const s=ca[e];if(s){const u=i(s);u&&o.extendAll(u)}return o}getZoomLevel(){const e=n=>{var r,i;return(i=(r=this.getScaleResolution(n))==null?void 0:r.getZoomLevel())!=null?i:1};return kr.map(e).reduce((n,r)=>n*r,1)}_initializeAggregateViews(){var e,n;if(Rh(this.spec))for(const r of this.spec.aggregateSamples){const i=(e=r.transform)!=null?e:[];i.length&&Cn(i).type!="collect"&&i.push({type:"collect"}),i.push({type:"mergeFacets"}),r.transform=i,r.encoding={...(n=r.encoding)!=null?n:{},sample:null};const o=this.context.createView(r,this,"summaryView");o.getFacetFields=s=>{},this.sampleAggregateViews.push(o)}}propagateInteractionEvent(e){e.target=this}getDefaultResolution(e,n){return e=="x"?"shared":"independent"}}function*ou(t,e=[]){for(const[n,r]of t.entries())if(r instanceof Map)for(const i of ou(r,[...e,n]))yield i;else yield[[...e,n],r]}class su extends J{constructor(e){super(),this.params=e!=null?e:{type:"collect"},this.observers=[],this.facetBatches=void 0,this._init()}_init(){this._data=[],this.facetBatches=new Pt([],JSON.stringify),this.facetBatches.set(void 0,this._data)}reset(){super.reset(),this._init()}handle(e){this._data.push(e)}beginBatch(e){pw(e)&&(this._data=[],this.facetBatches.set(Ke(e.facetId),this._data))}complete(){var i,o;const e=(i=this.params)==null?void 0:i.sort,n=e?yu(e.field,e.order):void 0,r=s=>{n&&s.sort(n)};if((o=this.params.groupby)!=null&&o.length){if(this.facetBatches.size>1)throw new Error("TODO: Support faceted data!");const s=this.params.groupby.map(u=>H(u)),a=di(this._data,...s);this.facetBatches.clear();for(const[u,c]of ou(a))this.facetBatches.set(u,c)}for(const s of this.facetBatches.values())r(s);if(this.children.length)for(const[s,a]of this.facetBatches.entries()){if(s){const u={type:"facet",facetId:s};for(const c of this.children)c.beginBatch(u)}for(const u of a)this._propagate(u)}super.complete();for(const s of this.observers)s(this)}getData(){switch(this._checkStatus(),this.facetBatches.size){case 0:return[];case 1:return[...this.facetBatches.values()][0];default:{const e=this.facetBatches;return{[Symbol.iterator]:function*(){for(const r of e.values())for(let i=0;i<r.length;i++)yield r[i]}}}}}visitData(e){this._checkStatus();for(const n of this.facetBatches.values())for(let r=0;r<n.length;r++)e(n[r])}getItemCount(){let e=0;for(const n of this.facetBatches.values())e+=n.length;return e}_checkStatus(){if(!this.completed)throw new Error("Data propagation is not completed! No data are available.")}}class Bo{constructor(){this.ids=[],this.values=[],this.length=0}clear(){this.length=0}push(e,n){let r=this.length++;for(;r>0;){const i=r-1>>1,o=this.values[i];if(n>=o)break;this.ids[r]=this.ids[i],this.values[r]=o,r=i}this.ids[r]=e,this.values[r]=n}pop(){if(this.length===0)return;const e=this.ids[0];if(this.length--,this.length>0){const n=this.ids[0]=this.ids[this.length],r=this.values[0]=this.values[this.length],i=this.length>>1;let o=0;for(;o<i;){let s=(o<<1)+1;const a=s+1;let u=this.ids[s],c=this.values[s];const f=this.values[a];if(a<this.length&&f<c&&(s=a,u=this.ids[a],c=f),c>=r)break;this.ids[o]=u,this.values[o]=c,o=s}this.ids[o]=n,this.values[o]=r}return e}peek(){if(this.length!==0)return this.ids[0]}peekValue(){if(this.length!==0)return this.values[0]}shrink(){this.ids.length=this.values.length=this.length}}class Vv extends J{get behavior(){return ut}constructor(e){super(),this.params=e,this.startAccessor=H(e.start),this.endAccessor=H(e.end),this.chromAccessor=e.chrom?H(e.chrom):n=>{},this.weightAccessor=e.weight?H(e.weight):n=>1,this.as={coverage:e.as||"coverage",start:e.asStart||e.start,end:e.asEnd||e.end,chrom:e.asChrom||e.chrom},this.createSegment=new Function("start","end","coverage","chrom","return {"+Object.entries(this.as).filter(([n,r])=>r).map(([n,r])=>`${JSON.stringify(r)}: ${n}`).join(", ")+"};"),this.ends=new Bo}reset(){super.reset(),this.initialize()}initialize(){const e=this.as.coverage,n=this.as.end,r=this.as.chrom,i=this.startAccessor,o=this.endAccessor,s=this.chromAccessor,a=this.weightAccessor;let u,c,f,l=0,h;const p=this.ends;p.clear();const d=(A,m,b)=>{if(A==m)return;let y=!1;u&&(u[e]===b?(u[n]=m,y=!0):u[e]!=0&&this._propagate(u)),y||(u=this.createSegment(A,m,b,f))},g=()=>{let A;for(;(A=p.peekValue())!==void 0;)d(h,A,l),h=A,l-=p.pop();h=void 0,u&&(this._propagate(u),u=void 0)};this.handle=A=>{const m=i(A);let b;for(;(b=p.peekValue())!==void 0&&b<m;)d(h,b,l),h=b,l-=p.pop();if(r){let w=s(A);w!==c&&(g(),f=w,c=f)}h!==void 0&&d(h,m,l),h=m;const y=a(A);l+=y,p.push(y,o(A))},this.complete=()=>{g(),super.complete()}}}function Yv(t,e,n=0,r=t.length){const i=new Bo,o=r-n;let s;for(s=0;s<e&&s<o;s++)i.push(s,t[n+s]);for(;s<o;s++){const c=t[n+s];c>=i.peekValue()&&(i.push(s,c),i.pop())}const a=[];let u;for(;(u=i.pop())!==void 0;)a.push(n+u);return a.reverse()}class Wv{constructor(e,n=-1/0,r=1/0){this.maxSize=e,this.lowerLimit=n,this.upperLimit=r;const i=this.maxSize*2+1;this.lowerLimits=new Float64Array(i),this.upperLimits=new Float64Array(i),this.lowerChildren=new Int32Array(i),this.upperChildren=new Int32Array(i),this.reset()}reset(){this.lowerLimits.fill(0),this.upperLimits.fill(0),this.lowerChildren.fill(0),this.upperChildren.fill(0),this.n=1,this.lowerLimits[0]=this.lowerLimit,this.upperLimits[0]=this.upperLimit}_findSlot(e,n,r=0){if(e>=this.lowerLimits[r]&&n<=this.upperLimits[r]){const i=this.lowerChildren[r];if(i){const o=this._findSlot(e,n,i);return o>=0?o:this._findSlot(e,n,this.upperChildren[r])}else return r}else return-1}reserve(e,n){if(n-e<=0)throw new Error("Cannot reserve an empty or negative-size slot!");if(this.n+1>this.lowerLimits.length)return!1;const r=this._findSlot(e,n);if(r<0)return!1;const i=this.n++,o=this.n++;return this.lowerLimits[i]=this.lowerLimits[r],this.upperLimits[i]=e,this.lowerLimits[o]=n,this.upperLimits[o]=this.upperLimits[r],this.lowerChildren[r]=i,this.upperChildren[r]=o,!0}}class Xv extends J{constructor(e,n){var i,o;if(super(),this.params=e,this._data=[],this.channel=(i=e.channel)!=null?i:"x",!["x","y"].includes(this.channel))throw new Error("Invalid channel: "+this.channel);this.posAccessor=H(this.params.pos),this.posBisector=hi(this.posAccessor),this.scoreAccessor=H(this.params.score),this.widthAccessor=H(this.params.width),this.laneAccessor=this.params.lane?H(this.params.lane):s=>0,this.padding=(o=this.params.padding)!=null?o:0,this.reservationMaps=new Map,this.resolution=n.getScaleResolution(this.channel);const r=()=>this._filterAndPropagate();this.schedule=()=>n.context.animator.requestTransition(r),this.resolution.addEventListener("domain",s=>this.schedule()),n._addBroadcastHandler("layoutComputed",()=>this.schedule())}complete(){const e=this.posAccessor;this._data.sort((n,r)=>e(n)-e(r)),this._scores=this._data.map(this.scoreAccessor);for(const n of new Set(this._data.map(this.laneAccessor)))this.reservationMaps.set(n,new Wv(200));this.schedule(),super.complete()}_filterAndPropagate(){var s;super.reset();const e=this.resolution.getScale(),n=(s=this.resolution.members[0].view.coords)==null?void 0:s[this.channel=="x"?"width":"height"];if(!n)return;for(const a of this.reservationMaps.values())a.reset();const r=e.domain(),i=70,o=Yv(this._scores,i,this.posBisector.left(this._data,r[0]),this.posBisector.right(this._data,r[1]));for(const a of o){const u=this._data[a],c=e(this.posAccessor(u))*n,f=this.widthAccessor(u)/2+this.padding;this.reservationMaps.get(this.laneAccessor(u)).reserve(c-f,c+f)&&this._propagate(u)}super.complete()}reset(){super.reset(),this._data=[],this.groups=new Map}handle(e){this._data.push(e)}}class Zv extends J{constructor(e){super(),this.params=e,this.predicate=void 0}initialize(){this.predicate=sa(this.params.expr,this.getGlobalObject())}handle(e){this.predicate(e)&&this._propagate(e)}}const Kv="0".charCodeAt(0);function*qv(t,e=","){const n=e.charCodeAt(0);let r=0;for(let i=0;i<t.length;i++){const o=t.charCodeAt(i);o==n?(yield r,r=0):r=r*10+o-Kv}yield r}class Jv extends J{get behavior(){return ut}constructor(e){var s,a;super();const n=H((s=e.exons)!=null?s:"exons"),r=H((a=e.start)!=null?a:"start"),[i,o]=e.as||["exonStart","exonEnd"];this.handle=u=>{let c=r(u),f=c,l=!0;const h=n(u);for(const p of qv(h)){if(l)f=c+p;else{c=f+p;const d=Object.assign({},u);d[i]=f,d[o]=c,this._propagate(d)}l=!l}}}}class _v extends J{get behavior(){return ut}constructor(e){super();const n=Ke(e.field).map(o=>H(o)),r=Ke(e.separator),i=Ke(e.as||e.field);if(n.length!==r.length||n.length!==i.length)throw new Error(`Lengths of "separator" (${r.length}), "fields" (${n.length}), and "as" (${i.length}) do not match!`);this.handle=o=>{if(n.some(u=>!u(o)))return;const s=n.map((u,c)=>u(o).split(r[c]));$v(s,o);const a=s[0].length;for(let u=0;u<a;u++){const c=Object.assign({},o);for(let f=0;f<n.length;f++)c[i[f]]=s[f][u];this._propagate(c)}}}}function $v(t,e){const n=t.map(r=>r.length);if(!n.every(r=>r==n[0]))throw new Error("Mismatching number of elements in the fields to be split: "+JSON.stringify(e))}class eC extends J{get behavior(){return Ft}constructor(e){super(),this.params=e,this.as=e.as,this.fn=void 0}initialize(){this.fn=sa(this.params.expr,this.getGlobalObject())}handle(e){e[this.as]=this.fn(e),this._propagate(e)}}class kh extends J{get behavior(){return Ft}constructor(e,n){var d;super();const r=(d=e.channel)!=null?d:"x";if(!["x","y"].includes(r))throw new Error("Invalid channel: "+r);const i=n.getScaleResolution(r).getGenome();if(!i)throw new Error("LinearizeGenomicCoordinate transform requires a locus scale!");const o=H(e.chrom),s=Ke(e.pos).map(g=>H(g)),a=Ke(e.as);if(s.length!=a.length)throw new Error('The number of "pos" and "as" elements must be equal!');const u=Ke(e.offset);let c;if(u.length==0)c=new Array(s.length).fill(0);else if(u.length==1)c=new Array(s.length).fill(u[0]);else if(u.length==s.length)c=u;else throw new Error(`Invalid "offset" parameter: ${JSON.stringify(e.offset)}!`);const f=new Function("datum","chromOffset","posAccessors",a.map((g,A)=>`datum[${JSON.stringify(g)}] = chromOffset + 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e=this.params,n=e.as||"lane",r=me(e.spacing)?e.spacing:1,i=H(e.start),o=H(e.end);if(!e.preference!=!e.preferredOrder)throw new Error('Must specify both "preference" and "preferredOrder"');if(e.preference){const s=new Float64Array(nC),a=H(e.preference),u=e.preferredOrder;let c=1/0;this.handle=f=>{const l=i(f);l<c&&s.fill(-1/0),c=l;const h=u.indexOf(a(f));let p=-1;if(h>=0&&s[h]<l)p=h;else{const d=i(f);for(p=0;p<s.length&&!(s[p]<d);p++);if(p>=s.length)throw new Error("Out of lanes!")}s[p]=o(f)+r,f[n]=p,this._propagate(f)}}else{const s=new Bo,a=new Bo;let u=-1/0,c=0;this.handle=f=>{const l=i(f);for(;s.length&&(s.peekValue()<=l||l<u);){const p=s.pop();a.push(p,p)}u=l;let h=a.pop();h===void 0&&(h=c++),f[n]=h,this._propagate(f),s.push(h,o(f)+r)}}}}class iC extends J{get behavior(){return ut}constructor(e){if(super(),e.as&&e.as.length!=e.fields.length)throw new Error('"fields" and "as" have unequal lengths!');const n=e.fields.map(i=>H(i)),r=e.as?e.as:n.map(K);this.handle=i=>{const o={};for(let s=0;s<n.length;s++)o[r[s]]=n[s](i);this._propagate(o)}}}class oC extends J{get behavior(){return Ft}constructor(e){super();const n=new RegExp(e.regex),r=typeof e.as=="string"?[e.as]:e.as,i=H(e.field);this.handle=o=>{const s=i(o);if(Z(s)){const a=s.match(n);if(a){if(a.length-1!=r.length)throw new Error('The number of RegEx groups and the length of "as" do not match!');for(let u=0;u<r.length;u++)o[r[u]]=a[u+1]}else if(e.skipInvalidInput)for(let u=0;u<r.length;u++)o[r[u]]=void 0;else throw new Error(`"${s}" does not match the given regex: ${n.toString()}`)}else if(!e.skipInvalidInput)throw new Error(`Trying to match a non-string field. Encountered type: ${typeof s}, field content: "${s}".`);this._propagate(o)}}}class sC extends J{get behavior(){return ut}constructor(e){super();const n=Ke(e.columnRegex).map(h=>new RegExp(h)),r=Ke(e.asValue);if(n.length!=r.length)throw new Error('Lengths of "columnRegex" and "as" are not equal!');const i=e.skipRegex?new RegExp(e.skipRegex):void 0,o=e.asKey||"sample";let s,a,u;const c=h=>{var A;const p=Object.keys(h),d=new Map;for(const[m,b]of n.entries())for(const y of p){const w=(A=b.exec(y))==null?void 0:A[1];if(w!==void 0){let E=d.get(w);E||(E=[],d.set(w,E)),E[m]=y}}s=[...d.entries()],a=p.filter(m=>!n.some(b=>b.test(m))&&!(i&&i.test(m)));const g=[...a.map(m=>JSON.stringify(m)+": datum["+JSON.stringify(m)+"]"),JSON.stringify(o)+": sampleId",...r.map(m=>JSON.stringify(m)+": null")];u=new Function("datum","sampleId",`return {
 `+g.join(`,
 `)+`

package/package.json

@@ -7,7 +7,7 @@
   },
   "contributors": [],
   "license": "BSD-2-Clause",
-  "version": "0.28.0",
+  "version": "0.28.1",
   "main": "dist/index.js",
   "module": "src/index.js",
   "exports": {
@@ -52,5 +52,6 @@
     "vega-loader": "^4.4.0",
     "vega-scale": "^7.1.1",
     "vega-util": "^1.16.0"
-  }
+  },
+  "gitHead": "afa6f0dad1d3b205e95a6335fd474cf7984021b3"
 }

package/src/view/gridView.js

@@ -431,9 +431,9 @@ export default class GridView extends ContainerView {
         let px = 0;
 
         const explicitSize =
-            (direction == "row" && this.spec.height) ||
+            (direction == "row" && this.spec.height) ??
             (direction == "column" && this.spec.width);
-        if (explicitSize !== undefined && explicitSize !== "") {
+        if (explicitSize || explicitSize === 0) {
             return parseSizeDef(explicitSize);
         }
 
@@ -507,14 +507,14 @@ export default class GridView extends ContainerView {
      * @returns {FlexDimensions}
      */
     getSize() {
-        return this._cache("size", () =>
-            new FlexDimensions(
-                this.#getFlexSize("column"),
-                this.#getFlexSize("row")
-            )
-                .subtractPadding(this.getOverhang())
-                .addPadding(this.getPadding())
-        );
+        //return this._cache("size", () =>
+        return new FlexDimensions(
+            this.#getFlexSize("column"),
+            this.#getFlexSize("row")
+        )
+            .subtractPadding(this.getOverhang())
+            .addPadding(this.getPadding());
+        //);
     }
 
     /**