@genome-spy/app 0.43.2 → 0.43.3
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/dist/index.es.js +1043 -1034
- package/dist/index.js +89 -86
- package/package.json +3 -3
package/dist/index.js
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(function(me,_e){typeof exports=="object"&&typeof module<"u"?_e(exports):typeof define=="function"&&define.amd?define(["exports"],_e):(me=typeof globalThis<"u"?globalThis:me||self,_e(me.genomeSpyApp={}))})(this,function(me){"use strict";var
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(function(me,_e){typeof exports=="object"&&typeof module<"u"?_e(exports):typeof define=="function"&&define.amd?define(["exports"],_e):(me=typeof globalThis<"u"?globalThis:me||self,_e(me.genomeSpyApp={}))})(this,function(me){"use strict";var lee=Object.defineProperty;var uee=(me,_e,De)=>_e in me?lee(me,_e,{enumerable:!0,configurable:!0,writable:!0,value:De}):me[_e]=De;var zn=(me,_e,De)=>(uee(me,typeof _e!="symbol"?_e+"":_e,De),De),Y2=(me,_e,De)=>{if(!_e.has(me))throw TypeError("Cannot "+De)};var F=(me,_e,De)=>(Y2(me,_e,"read from private field"),De?De.call(me):_e.get(me)),Z=(me,_e,De)=>{if(_e.has(me))throw TypeError("Cannot add the same private member more than once");_e instanceof WeakSet?_e.add(me):_e.set(me,De)},le=(me,_e,De,Vo)=>(Y2(me,_e,"write to private field"),Vo?Vo.call(me,De):_e.set(me,De),De);var UT=(me,_e,De,Vo)=>({set _(Bf){le(me,_e,Bf,De)},get _(){return F(me,_e,Vo)}}),J=(me,_e,De)=>(Y2(me,_e,"access private method"),De);var 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@@ -1691,33 +1691,36 @@ void main() {
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* All rights reserved.
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*
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* BSD-3-Clause License: https://github.com/vega/vega-lite/blob/master/LICENSE
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*/const pN="locus",gN="index";var mN=5;function bN(e){const t=e.type;return!e.bins&&(t===es||t===pl||t===gl)}function iE(e){return _t(e)&&![dr,gN,pN].includes(e)}function aE(e){return e||{warn:(t,...n)=>console.warn(t,...n)}}var yN=zf(["set","modified","clear","type","scheme","schemeExtent","schemeCount","domain","domainMin","domainMid","domainMax","domainRaw","domainImplicit","nice","zero","bins","range","rangeStep","round","reverse","interpolate","interpolateGamma","zoom","fp64","name"]);function oE(e,t,n){n=aE(n);for(const r in e)if(!yN[r]){if(r==="padding"&&iE(t.type))continue;Kt(t[r])?t[r](e[r]):n.warn("Unsupported scale property: "+r)}CN(t,e,_N(t,e,AN(t,e,n)))}function vN(e,t){const n=wN(e),r=ke(n);if(!r)throw new Error("Unknown scale type: "+n);const i=r();return!e.domain&&_t(i.type)&&(e.domain=[0,0]),oE(e,i,t),i}function wN(e){var t=e.type,n="",r;return t===dr?dr+"-"+es:(xN(e)&&(r=e.rawDomain?e.rawDomain.length:e.domain?e.domain.length+ +(e.domainMid!=null):0,n=r===2?dr+"-":r===3?ts+"-":""),(n+t||es).toLowerCase())}function xN(e){const t=e.type;return _t(t)&&t!==Kx&&t!==Jx&&(e.scheme||e.range&&e.range.length&&e.range.every(Me))}function AN(e,t,n){if(!e.domain)return 0;n=aE(n);var r=EN(e,t.domainRaw,n);if(r>-1)return r;var i=t.domain,a=e.type,o=t.zero||t.zero===void 0&&bN(e),s,c;return i?(iE(a)&&t.padding&&i[0]!==Un(i)&&(i=SN(a,i,t.range,t.padding,t.exponent,t.constant)),(o||t.domainMin!=null||t.domainMax!=null||t.domainMid!=null)&&(s=(i=i.slice()).length-1||1,o&&(i[0]>0&&(i[0]=0),i[s]<0&&(i[s]=0)),t.domainMin!=null&&(i[0]=t.domainMin),t.domainMax!=null&&(i[s]=t.domainMax),t.domainMid!=null&&(c=t.domainMid,(c<i[0]||c>i[s])&&n.warn("Scale domainMid exceeds domain min or max.",c),i.splice(s,0,c))),e.domain(sE(a,i,n)),a===Yg&&e.unknown(t.domainImplicit?gg:void 0),t.nice&&e.nice&&e.nice(t.nice!==!0&&nE(e,t.nice)||null),i.length):0}function EN(e,t,n){return t?(e.domain(sE(e.type,t,n)),t.length):-1}function SN(e,t,n,r,i,a){var o=Math.abs(Un(n)-n[0]),s=o/(o-2*r),c=e===Ti?uv(t,null,s):e===gl?Ap(t,null,s,.5):e===pl?Ap(t,null,s,i||1):e===Ah?vI(t,null,s,a||1):xp(t,null,s);return t=t.slice(),t[0]=c[0],t[t.length-1]=c[1],t}function sE(e,t,n){if(o3(e)){var r=Math.abs(t.reduce(function(i,a){return i+(a<0?-1:a>0?1:0)},0));r!==t.length&&n.warn("Log scale domain includes zero: "+Nf(t))}return t}function _N(e,t,n){let r=t.bins;if(r&&!Qt(r)){const i=(r.start==null||r.stop==null)&&e.domain(),a=r.start==null?i[0]:r.start,o=r.stop==null?Un(i):r.stop,s=r.step;s||it("Scale bins parameter missing step property."),r=mi(a,o+s,s)}return r?e.bins=r:e.bins&&delete e.bins,e.type===Qg&&(r?!t.domain&&!t.domainRaw&&(e.domain(r),n=r.length):e.bins=e.domain()),n}function CN(e,t,n){var r=e.type,i=t.round||!1,a=t.range;if(t.rangeStep!=null)a=kN(r,t,n);else if(t.scheme&&(a=TN(r,t,n),Kt(a))){if(e.interpolator)return e.interpolator(a);it(`Scale type ${r} does not support interpolating color schemes.`)}if(a&&Sh(r))return e.interpolator(_h(Gm(a,t.reverse),t.interpolate,t.interpolateGamma));a&&t.interpolate&&e.interpolate?e.interpolate(s3(t.interpolate,t.interpolateGamma)):Kt(e.round)?e.round(i):Kt(e.rangeRound)&&e.interpolate(i?hl:Ci),a&&e.range(Gm(a,t.reverse))}function kN(e,t,n){e!==n3&&e!==Zg&&it("Only band and point scales support rangeStep.");var r=(t.paddingOuter!=null?t.paddingOuter:t.padding)||0,i=e===Zg?1:(t.paddingInner!=null?t.paddingInner:t.padding)||0;return[0,t.rangeStep*qg(n,i,r)]}function TN(e,t,n){var r=t.schemeExtent,i,a;return Qt(t.scheme)?a=_h(t.scheme,t.interpolate,t.interpolateGamma):(i=t.scheme.toLowerCase(),a=Kg(i),a||it(`Unrecognized scheme name: ${t.scheme}`)),n=e===t3?n+1:e===Qg?n-1:e===Wg||e===e3?+t.schemeCount||mN:n,Sh(e)?cE(a,r,t.reverse):Kt(a)?HB(cE(a,r),n):e===Yg?a:a.slice(0,n)}function cE(e,t,n){return Kt(e)&&(t||n)?$B(e,Gm(t||[0,1],n)):e}function Gm(e,t){return t?e.slice().reverse():e}const Vm=pt(",d");function IN(e){return e.chrom+":"+Vm(Math.floor(e.pos+1))}function lE(e){return!ft(e)&&"chrom"in e?IN(e):""+e}function RN(e,t){return e.chrom+":"+Vm(Math.floor(e.pos+1))+"-"+(e.chrom!=t.chrom?t.chrom+":":"")+Vm(Math.ceil(t.pos))}const DN="https://genomespy.app/data/genomes/";class BN{constructor(t){if(this.config=t,!this.config.contigs&&typeof this.config.name!="string")throw new Error("No name has been defined for the genome assembly!");this.chromosomes=[],this.cumulativeChromPositions=new Map,this.chromosomesByName=new Map,this.startByIndex=[],this.totalSize=0,this.config.contigs&&this.setChromSizes(this.config.contigs)}get name(){return this.config.name}async load(t){if(!this.config.contigs){this.config.baseUrl?this.baseUrl=/^http(s)?/.test(this.config.baseUrl)?this.config.baseUrl:t+"/"+this.config.baseUrl:this.baseUrl=DN;try{this.setChromSizes(FN(await Zc({baseURL:this.baseUrl}).load(`${this.config.name}/${this.name}.chrom.sizes`)))}catch(n){throw new Error(`Could not load chrom sizes: ${n.message}`)}}}hasChrPrefix(){return this.chromosomes.some(t=>t.name.startsWith("chr"))}setChromSizes(t){let n=0;this.startByIndex=[0];for(let r=0;r<t.length;r++){this.startByIndex.push(n);const i=t[r].size,a={...t[r],continuousStart:n,continuousEnd:n+i,continuousInterval:[n,n+i],index:r,number:r+1,odd:!(r&1)};this.chromosomes.push(a);const o=a.name.replace(/^chr/i,"");for(const s of["chr"+o,"CHR"+o,"Chr"+o,a.number,""+a.number,o,a.name])this.cumulativeChromPositions.set(s,n),this.chromosomesByName.set(s,a);n+=a.size}this.totalSize=n}getExtent(){return[0,this.totalSize]}toContinuous(t,n){let r=this.cumulativeChromPositions.get(t);if(r===void 0)throw new Error("Unknown chromosome/contig: "+t);return r+ +n}toChromosome(t){if(t>this.totalSize)return;t=Math.floor(t);const n=Pr(this.startByIndex,t)-1;if(n>0&&n<=this.chromosomes.length)return this.chromosomes[n-1]}toChromosomal(t){const n=this.toChromosome(t);if(n)return{chrom:n.name,pos:Math.floor(t)-n.continuousStart}}getChromosome(t){return this.chromosomesByName.get(t)}formatInterval(t){return RN(...this.toChromosomalInterval(t))}toChromosomalInterval(t){const n=this.toChromosomal(t[0]+.5),r=this.toChromosomal(t[1]-.5);return r.pos+=1,[n,r]}toContinuousInterval(t){var i;let[n,r]=t;return r||(r=n),[this.toContinuous(n.chrom,n.pos??0),this.toContinuous(r.chrom,r.pos??((i=this.chromosomesByName.get(r.chrom))==null?void 0:i.size))]}toDiscreteChromosomeIntervals(t){const n=t[0],r=t[1],i=[];if(n.chrom===r.chrom)i.push({chrom:n.chrom,startPos:n.pos,endPos:r.pos});else{const a=this.chromosomes.findIndex(s=>s.name===n.chrom),o=this.chromosomes.findIndex(s=>s.name===r.chrom);i.push({chrom:n.chrom,startPos:n.pos,endPos:this.chromosomes[a].size});for(let s=a+1;s<o;s++)i.push({chrom:this.chromosomes[s].name,startPos:0,endPos:this.chromosomes[s].size});i.push({chrom:r.chrom,startPos:0,endPos:r.pos})}return i}continuousToDiscreteChromosomeIntervals(t){return this.toDiscreteChromosomeIntervals([this.toChromosomal(t[0]),this.toChromosomal(t[1])])}parseInterval(t){const n=t.match(/^(chr[0-9A-Z]+)(?::([0-9,]+)(?:-(?:(chr[0-9A-Z]+):)?([0-9,]+))?)?$/);if(n){const r=n[1];if(n.slice(2).every(s=>s===void 0)){const s=this.getChromosome(r);return s?[s.continuousStart,s.continuousEnd]:void 0}const i=n[3]||r,a=parseInt(n[2].replace(/,/g,"")),o=n[4]!==void 0?parseInt(n[4].replace(/,/g,"")):a;return[this.toContinuous(r,a-1),this.toContinuous(i,o)]}}}function FN(e){return NI(e).filter(t=>/^chr[0-9A-Z]+$/.test(t[0])).map(([t,n])=>({name:t,size:parseInt(n)}))}function td(e){return Xt(e)&&"chrom"in e}function PN(e){return e.every(td)}class Ml extends Array{constructor(){super(),this.type=void 0}extend(t){return this}extendAll(t){if(t instanceof Ml&&t.type!=this.type)throw new Error(`Cannot combine different types of domains: ${this.type} and ${t.type}`);for(const n of t)this.extend(n);return this}extendAllWithAccessor(t,n){for(const r of t)this.extend(n(r));return this}}class jm extends Ml{constructor(){super(),this.type="quantitative"}extend(t){return t==null||Number.isNaN(t)?this:(t=+t,this.length?t<this[0]?this[0]=t:t>this[1]&&(this[1]=t):(this.push(t),this.push(t)),this)}}class uE extends Ml{constructor(){super(),this.type="ordinal",this.uniqueValues=new Set}extend(t){return t==null||Number.isNaN(t)?this:(this.uniqueValues.has(t)||(this.uniqueValues.add(t),this.push(t)),this)}}class fE extends uE{constructor(){super(),this.type="nominal"}}class MN extends Ml{constructor(t){super();let n=0;for(let r=1;r<t.length;r++)n+=Math.sign(t[r]-t[r-1]);if(Math.abs(n)!=t.length-1)throw new Error("Piecewise domain must be strictly increasing or decreasing: "+JSON.stringify(t));t.forEach(r=>this.push(r))}extend(t){if(this.includes(t))return this;throw new Error("Piecewise domains are immutable and cannot be unioned!")}}const hE={quantitative:jm,index:jm,locus:jm,nominal:fE,ordinal:uE};function dE(e,t){if(e=="quantitative"&&ON(t)){const n=new MN(t);return n.type=e,n}else if(hE[e]){const n=new hE[e];return n.type=e,t&&n.extendAll(t),n}throw new Error("Unknown type: "+e)}function ON(e){return e&&e.length>0&&e.length!=2&&e.every(t=>typeof t=="number")}function LN(e){return((e*=2)<=1?e*e:--e*(2-e)+1)/2}function NN(e){return--e*e*e+1}function zN(e){return((e*=2)<=1?e*e*e:(e-=2)*e*e+2)/2}function UN(e){return(Math.pow(2,-10*e)-.0009765625)*1.0009775171065494}function $N(e){return 1-UN(e)}function HN(e,t,n){return e*Math.pow(t/e,n)}ke("index",Hm,["continuous"]),ke("locus",aN,["continuous"]),ke("null",Ch,[]);const pE="quantitative",qm="ordinal",Wm="nominal",gE="locus",GN="index";class VN{constructor(t){Z(this,Dr);Z(this,Z0);Z(this,fc);Z(this,oi);Z(this,lf);Z(this,Q0);Z(this,V2);Z(this,uf);Z(this,ai,void 0);Z(this,uc,new Set);Z(this,Ot,void 0);this.channel=t,this.members=[],this.type=null,this.name=void 0}addEventListener(t,n){if(t!="domain")throw new Error("Unsupported event type: "+t);F(this,uc).add(n)}removeEventListener(t,n){if(t!="domain")throw new Error("Unsupported event type: "+t);F(this,uc).delete(n)}pushUnitView(t,n){var o;const r=Jg(t,n),i=r.type,a=(o=r==null?void 0:r.scale)==null?void 0:o.name;if(a){if(this.name!==void 0&&a!=this.name)throw new Error(`Shared scales have conflicting names: "${a}" vs. "${this.name}"!`);this.name=a}if(!this.type)this.type=i;else if(i!==this.type&&!xl(n))throw new Error(`Can not use shared scale for different data types: ${this.type} vs. ${i}. Use "resolve: independent" for channel ${this.channel}`);this.members.push({view:t,channel:n})}isExplicitDomain(){return!!this.getConfiguredDomain()}isDomainInitialized(){const t=F(this,Ot);if(!t)return!1;const n=t.domain();return _t(t.type)?n.length>2||n.length==2&&(n[0]!==0||n[1]!==0):n.length>0}getScaleProps(){return ds(this,"scaleProps",()=>{const t=J(this,Z0,VT).call(this);if(t===null||t.type=="null")return{type:"null"};const n={...J(this,Q0,jT).call(this,this.type),...t};n.type||(n.type=jN(this.channel,this.type));const r=J(this,fc,yp).call(this);return r&&r.length>0?n.domain=r:Vn(n.type)&&(n.domain=new fE),!n.domain&&n.domainMid!==void 0&&(n.domain=[n.domainMin??0,n.domainMax??1]),this.channel=="y"&&Vn(n.type)&&n.reverse==null&&(n.reverse=!0),n.range&&n.scheme&&delete n.scheme,!("zoom"in n)&&["index","locus"].includes(n.type)&&(n.zoom=!0),qN(n,this.channel),n})}getConfiguredDomain(){return J(this,uf,ev).call(this,t=>xl(t.channel)?void 0:t.view.getConfiguredDomain(t.channel))}getDataDomain(){return J(this,uf,ev).call(this,t=>xl(t.channel)?void 0:t.view.extractDataDomain(t.channel))}reconfigure(){if(F(this,Ot)&&F(this,Ot).type!="null"){const t=this.isDomainInitialized(),n=F(this,Ot).domain();NA(this,"scaleProps");const r=this.getScaleProps();if(oE(r,F(this,Ot)),_t(F(this,Ot).type)&&le(this,ai,J(this,lf,J2).call(this)),!t){J(this,Dr,ya).call(this);return}const i=F(this,Ot).domain();th(i,n)||(this.isZoomable()?F(this,Ot).domain(n):J(this,oi,Ho).call(this)?(F(this,Ot).domain(n),this.zoomTo(i,500)):J(this,Dr,ya).call(this))}}getScale(){if(F(this,Ot))return F(this,Ot);const t=this.getScaleProps(),n=vN(t);return le(this,Ot,n),oN(n)&&n.genome(this.getGenome()),_t(n.type)&&le(this,ai,J(this,lf,J2).call(this)),n}getDomain(){return this.getScale().domain()}getComplexDomain(){var t;return((t=this.getGenome())==null?void 0:t.toChromosomalInterval(this.getDomain()))??this.getDomain()}isZoomed(){return J(this,oi,Ho).call(this)&&th(J(this,fc,yp).call(this),this.getDomain())}isZoomable(){return J(this,oi,Ho).call(this)&&!!this.getScaleProps().zoom}zoom(t,n,r){if(!J(this,oi,Ho).call(this))return!1;const i=this.getScale(),a=i.domain();let o=[...a],s=i.invert(n);switch(this.getScaleProps().reverse&&(r=-r),"align"in i&&(s+=i.align()),i.type){case"linear":case"index":case"locus":o=mI(o,r||0),o=xp(o,s,t);break;case"log":o=bI(o,r||0),o=uv(o,s,t);break;case"pow":case"sqrt":{const c=i;o=yI(o,r||0,c.exponent()),o=Ap(o,s,t,c.exponent());break}default:throw new Error("Zooming is not implemented for: "+i.type)}return F(this,ai)&&(o=wI(o,F(this,ai)[0],F(this,ai)[1])),[0,1].some(c=>o[c]!=a[c])?(i.domain(o),J(this,Dr,ya).call(this),!0):!1}async zoomTo(t,n=!1){var s;if(kc(n)&&(n=n?700:0),!J(this,oi,Ho).call(this))throw new Error("Not a zoomable scale!");const r=this.fromComplexInterval(t),i=(s=this.members[0])==null?void 0:s.view.context.animator,a=this.getScale(),o=a.domain();if(n>0&&o.length==2){const c=o[1]-o[0],l=o[0]+c/2,u=r[1]-r[0],f=r[0]+u/2;await i.transition({duration:n,easingFunction:zN,onUpdate:h=>{const d=HN(c,u,h),p=(c-d)/(c-u),g=p*f+(1-p)*l;a.domain([g-d/2,g+d/2]),J(this,Dr,ya).call(this)}}),a.domain(r),J(this,Dr,ya).call(this)}else a.domain(r),i==null||i.requestRender(),J(this,Dr,ya).call(this)}resetZoom(){if(!J(this,oi,Ho).call(this))throw new Error("Not a zoomable scale!");const t=this.getDomain(),n=J(this,fc,yp).call(this);return[0,1].some(r=>n[r]!=t[r])?(F(this,Ot).domain(n),J(this,Dr,ya).call(this),!0):!1}getZoomLevel(){return this.isZoomable()?Lf(F(this,ai))/Lf(this.getScale().domain()):1}getGenome(){var n;if(this.type!=="locus")return;const t=(n=this.members[0].view.context.genomeStore)==null?void 0:n.getGenome();if(!t)throw new Error("No genome has been defined!");return t}invertToComplex(t){const n=this.getScale();if("invert"in n){const r=n.invert(t);return 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${this.getMarkType()}`);this.resolve(),this.needsAxes={x:!0,y:!0}}render(t,n,r={}){super.render(t,n,r),this.isConfiguredVisible()&&(t.pushView(this,n),t.renderMark(this.mark,r),t.popView(this))}getMarkType(){return typeof this.spec.mark=="object"?this.spec.mark.type:this.spec.mark}resolve(t){t||(this.resolve("scale"),this.resolve("axis"));const n=this.mark.encoding;for(const[r,i]of Object.entries(n)){if(!rn(i))continue;const a=$a(i.resolutionChannel??r);if(!Ri(a)||t=="axis"&&!wl(a))continue;let o=this;for(;(o.getConfiguredOrDefaultResolution(a,t)=="forced"||o.dataParent instanceof Yn&&["shared","excluded","forced"].includes(o.dataParent.getConfiguredOrDefaultResolution(a,t)))&&o.getConfiguredOrDefaultResolution(a,t)!="excluded";)o=o.dataParent;t=="axis"&&wl(r)&&h3(a)?(o.resolutions[t][a]||(o.resolutions[t][a]=new YN(a)),o.resolutions[t][a].pushUnitView(this,r)):t=="scale"&&Ri(r)&&(o.resolutions[t][a]||(o.resolutions[t][a]=new VN(a)),o.resolutions[t][a].pushUnitView(this,r))}}getAccessor(t){return this._cache("accessor/"+t,()=>{const n=this.mark.encoding;if(n&&n[t])return this.context.accessorFactory.createAccessor(n[t])})}getFacetAccessor(t){const n=this.getAccessor("sample");return n||super.getFacetAccessor(this)}getCollector(){return this.context.dataFlow.findCollectorByKey(this)}_validateDomainQuery(t){if(xl(t))throw new Error(`getDomain(${t}), must only be called for primary channels!`);const n=this.mark.encoding[t];if(!rn(n))throw new Error("The channel has no scale, cannot get domain!");return n}getConfiguredDomain(t){const n=this._validateDomainQuery(t),r=n&&n.scale&&n.scale.domain;if(r){const i=this.getScaleResolution(n.resolutionChannel??t);return dE(n.type??"nominal",i.fromComplexInterval(r))}}extractDataDomain(t){const r=this._validateDomainQuery(t).type??"nominal",i=s=>{let c;const l=this.mark.encoding[s];if(l){const 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0,this._data)}reset(){super.reset(),this._init()}handle(t){this._data.push(t)}beginBatch(t){TL(t)&&(this._data=[],this.facetBatches.set(Lt(t.facetId),this._data))}complete(){var i,a;const t=(i=this.params)==null?void 0:i.sort,n=t?fv(t.field,t.order):void 0,r=o=>{n&&o.sort(n)};if((a=this.params.groupby)!=null&&a.length){if(this.facetBatches.size>1)throw new Error("TODO: Support faceted data!");const o=this.params.groupby.map(c=>Oe(c)),s=o.length>1?Rc(this._data,...o):QN(this._data,o[0]);this.facetBatches.clear();for(const[c,l]of Qm(s))this.facetBatches.set(c,l)}for(const o of this.facetBatches.values())r(o);if(this.children.length)for(const[o,s]of this.facetBatches.entries()){if(o){const c={type:"facet",facetId:o};for(const l of this.children)l.beginBatch(c)}for(const c of s)this._propagate(c)}super.complete();for(const o of this.observers)o(this)}getData(){switch(this._checkStatus(),this.facetBatches.size){case 0:return[];case 1:return[...this.facetBatches.values()][0];default:{const t=this.facetBatches;return{[Symbol.iterator]:function*(){for(const r of t.values())for(let i=0;i<r.length;i++)yield r[i]}}}}}visitData(t){this._checkStatus();for(const n of this.facetBatches.values())for(let r=0;r<n.length;r++)t(n[r])}getItemCount(){let t=0;for(const n of this.facetBatches.values())t+=n.length;return t}_checkStatus(){if(!this.completed)throw new Error("Data propagation is not completed! No data are available.")}}function QN(e,t){const n=new Map;for(let r=0,i=e.length;r<i;r++){const a=e[r],o=t(a);let s=n.get(o);s||(s=[],n.set(o,s)),s.push(a)}return n}class Ll{constructor(){this.ids=[],this.values=[],this.length=0}clear(){this.length=0}push(t,n){let r=this.length++;for(;r>0;){const i=r-1>>1,a=this.values[i];if(n>=a)break;this.ids[r]=this.ids[i],this.values[r]=a,r=i}this.ids[r]=t,this.values[r]=n}pop(){if(this.length===0)return;const t=this.ids[0];if(this.length--,this.length>0){const n=this.ids[0]=this.ids[this.length],r=this.values[0]=this.values[this.length],i=this.length>>1;let a=0;for(;a<i;){let o=(a<<1)+1;const s=o+1;let c=this.ids[o],l=this.values[o];const u=this.values[s];if(s<this.length&&u<l&&(o=s,c=this.ids[s],l=u),l>=r)break;this.ids[a]=c,this.values[a]=l,a=o}this.ids[a]=n,this.values[a]=r}return t}peek(){if(this.length!==0)return this.ids[0]}peekValue(){if(this.length!==0)return this.values[0]}shrink(){this.ids.length=this.values.length=this.length}}class XN extends at{get behavior(){return mr}constructor(t){super(),this.params=t,this.startAccessor=Oe(t.start),this.endAccessor=Oe(t.end),this.chromAccessor=t.chrom?Oe(t.chrom):n=>{},this.weightAccessor=t.weight?Oe(t.weight):n=>1,this.as={coverage:t.as||"coverage",start:t.asStart||t.start,end:t.asEnd||t.end,chrom:t.asChrom||t.chrom},this.createSegment=new Function("start","end","coverage","chrom","return {"+Object.entries(this.as).filter(([n,r])=>r).map(([n,r])=>`${JSON.stringify(r)}: ${n}`).join(", ")+"};"),this.ends=new Ll}reset(){super.reset(),this.initialize()}initialize(){const t=this.as.coverage,n=this.as.end,r=this.as.chrom,i=this.startAccessor,a=this.endAccessor,o=this.chromAccessor,s=this.weightAccessor;let c,l,u,f=0,h;const d=this.ends;d.clear();const p=(b,y,w)=>{if(b==y)return;let A=!1;c&&(c[t]===w?(c[n]=y,A=!0):c[t]!=0&&this._propagate(c)),A||(c=this.createSegment(b,y,w,u))},g=()=>{let b=0;for(;(b=d.peekValue())!==void 0;)p(h,b,f),h=b,f-=d.pop();h=void 0,c&&(this._propagate(c),c=void 0)};this.handle=b=>{const y=i(b);let w=0;for(;(w=d.peekValue())!==void 0&&w<y;)p(h,w,f),h=w,f-=d.pop();if(r){let x=o(b);x!==l&&(g(),u=x,l=u)}h!==void 0&&p(h,y,f),h=y;const A=s(b);f+=A,d.push(A,a(b))},this.complete=()=>{g(),super.complete()},this.beginBatch=b=>{g(),l=void 0,super.beginBatch(b)}}}function KN(e,t,n=0,r=e.length){const i=new Ll,a=r-n;let o;for(o=0;o<t&&o<a;o++)i.push(o,e[n+o]);for(;o<a;o++){const l=e[n+o];l>=i.peekValue()&&(i.push(o,l),i.pop())}const s=[];let c;for(;(c=i.pop())!==void 0;)s.push(n+c);return s.reverse()}class JN{constructor(t,n=-1/0,r=1/0){this.maxSize=t,this.lowerLimit=n,this.upperLimit=r;const i=this.maxSize*2+1;this.lowerLimits=new Float64Array(i),this.upperLimits=new Float64Array(i),this.lowerChildren=new Int32Array(i),this.upperChildren=new Int32Array(i),this.reset()}reset(){this.lowerLimits.fill(0),this.upperLimits.fill(0),this.lowerChildren.fill(0),this.upperChildren.fill(0),this.n=1,this.lowerLimits[0]=this.lowerLimit,this.upperLimits[0]=this.upperLimit}_findSlot(t,n,r=0){if(t>=this.lowerLimits[r]&&n<=this.upperLimits[r]){const i=this.lowerChildren[r];if(i){const a=this._findSlot(t,n,i);return a>=0?a:this._findSlot(t,n,this.upperChildren[r])}else return r}else return-1}reserve(t,n){if(n-t<=0)throw new Error("Cannot reserve an empty or negative-size slot!");if(this.n+1>this.lowerLimits.length)return!1;const r=this._findSlot(t,n);if(r<0)return!1;const i=this.n++,a=this.n++;return this.lowerLimits[i]=this.lowerLimits[r],this.upperLimits[i]=t,this.lowerLimits[a]=n,this.upperLimits[a]=this.upperLimits[r],this.lowerChildren[r]=i,this.upperChildren[r]=a,!0}}class ez extends at{get behavior(){return zm}constructor(t,n){if(super(),this.params=t,this._data=[],this.channel=t.channel??"x",!["x","y"].includes(this.channel))throw new Error("Invalid channel: "+this.channel);this.posAccessor=Oe(this.params.pos),this.posBisector=Uf(this.posAccessor),this.scoreAccessor=Oe(this.params.score),this.widthAccessor=Oe(this.params.width),this.laneAccessor=this.params.lane?Oe(this.params.lane):i=>0,this.padding=this.params.padding??0,this.reservationMaps=new Map,this.resolution=n.getScaleResolution(this.channel);const r=()=>this._filterAndPropagate();this.schedule=()=>n.context.animator.requestTransition(r),this.resolution.addEventListener("domain",i=>this.schedule()),n._addBroadcastHandler("layoutComputed",()=>this.schedule())}complete(){const t=this.posAccessor;this._data.sort((n,r)=>t(n)-t(r)),this._scores=this._data.map(this.scoreAccessor);for(const n of new Set(this._data.map(this.laneAccessor)))this.reservationMaps.set(n,new JN(200));this.schedule(),super.complete()}_filterAndPropagate(){var o;super.reset();const t=this.resolution.getScale(),n=(o=this.resolution.members[0].view.coords)==null?void 0:o[this.channel=="x"?"width":"height"];if(!n)return;for(const s of this.reservationMaps.values())s.reset();const r=t.domain(),i=70,a=KN(this._scores,i,this.posBisector.left(this._data,r[0]),this.posBisector.right(this._data,r[1]));for(const s of a){const c=this._data[s],l=t(this.posAccessor(c))*n,u=this.widthAccessor(c)/2+this.padding;this.reservationMaps.get(this.laneAccessor(c)).reserve(l-u,l+u)&&this._propagate(c)}super.complete()}reset(){super.reset(),this._data=[],this.groups=new Map}handle(t){this._data.push(t)}}class tz extends at{constructor(t){super(),this.params=t,this.predicate=void 0}initialize(){this.predicate=ch(this.params.expr,this.getGlobalObject())}handle(t){this.predicate(t)&&this._propagate(t)}}class nz extends at{get behavior(){return mr}constructor(t){super();const n=t.index;if(t.fields){const r=Lt(t.fields).map(a=>Oe(a)),i=Lt(t.as||t.fields);if(r.length!==i.length)throw new Error(`Lengths of "fields" (${r.length}), and "as" (${i.length}) do not match!`);this.handle=a=>{const o=r.map((c,l)=>c(a)??[]),s=o[0].length;for(let c=0;c<s;c++){const l=Object.assign({},a);for(let u=0;u<r.length;u++)l[i[u]]=c<o[u].length?o[u][c]:null;n&&(l[n]=c),this._propagate(l)}}}else this.handle=r=>{for(let i=0;i<r.length;i++){const a=Object.assign({},r[i]);n&&(a[n]=i),this._propagate(a)}}}}const rz="0".charCodeAt(0);function*iz(e,t=","){const n=t.charCodeAt(0);let r=0;for(let i=0;i<e.length;i++){const a=e.charCodeAt(i);a==n?(yield r,r=0):r=r*10+a-rz}yield r}class az extends at{get behavior(){return mr}constructor(t){super();const n=Oe(t.exons??"exons"),r=Oe(t.start??"start"),[i,a]=t.as||["exonStart","exonEnd"];this.handle=o=>{let s=r(o),c=s,l=!0;const u=n(o);for(const f of iz(u)){if(l)c=s+f;else{s=c+f;const h=Object.assign({},o);h[i]=c,h[a]=s,this._propagate(h)}l=!l}}}}class oz extends at{get behavior(){return mr}constructor(t){super();const n=Lt(t.field).map(a=>Oe(a)),r=Lt(t.separator),i=Lt(t.as||t.field);if(n.length!==r.length||n.length!==i.length)throw new Error(`Lengths of "separator" (${r.length}), "fields" (${n.length}), and "as" (${i.length}) do not match!`);this.handle=a=>{if(n.some(c=>!c(a)))return;const o=n.map((c,l)=>c(a).split(r[l]));sz(o,a);const s=o[0].length;for(let c=0;c<s;c++){const l=Object.assign({},a);for(let u=0;u<n.length;u++)l[i[u]]=o[u][c];this._propagate(l)}}}}function sz(e,t){const n=e.map(r=>r.length);if(!n.every(r=>r==n[0]))throw new Error("Mismatching number of elements in the fields to be split: "+JSON.stringify(t))}class cz extends at{get behavior(){return Li}constructor(t){super(),this.params=t,this.as=t.as,this.fn=void 0}initialize(){this.fn=ch(this.params.expr,this.getGlobalObject())}handle(t){t[this.as]=this.fn(t),this._propagate(t)}}class mE extends at{get behavior(){return Li}constructor(t,n){super();const r=t.channel??"x";if(!["x","y"].includes(r))throw new Error("Invalid channel: "+r);const i=n.getScaleResolution(r).getGenome();if(!i)throw new Error("LinearizeGenomicCoordinate transform requires a locus scale!");const a=Oe(t.chrom),o=Lt(t.pos).map(p=>Oe(p)),s=Lt(t.as);if(o.length!=s.length)throw new Error('The number of "pos" and "as" elements must be equal!');const c=Lt(t.offset);let l;if(c.length==0)l=new Array(o.length).fill(0);else if(c.length==1)l=new Array(o.length).fill(c[0]);else if(c.length==o.length)l=c;else throw new Error(`Invalid "offset" parameter: ${JSON.stringify(t.offset)}!`);const u=new Function("datum","chromOffset","posAccessors",s.map((p,g)=>`datum[${JSON.stringify(p)}] = chromOffset + +posAccessors[${g}](datum) - ${l[g]};`).join(`
|
|
1694
|
+
*/const pN="locus",gN="index";var mN=5;function bN(e){const t=e.type;return!e.bins&&(t===es||t===pl||t===gl)}function iE(e){return _t(e)&&![dr,gN,pN].includes(e)}function aE(e){return e||{warn:(t,...n)=>console.warn(t,...n)}}var yN=zf(["set","modified","clear","type","scheme","schemeExtent","schemeCount","domain","domainMin","domainMid","domainMax","domainRaw","domainImplicit","nice","zero","bins","range","rangeStep","round","reverse","interpolate","interpolateGamma","zoom","fp64","name"]);function oE(e,t,n){n=aE(n);for(const r in e)if(!yN[r]){if(r==="padding"&&iE(t.type))continue;Kt(t[r])?t[r](e[r]):n.warn("Unsupported scale property: "+r)}CN(t,e,_N(t,e,AN(t,e,n)))}function vN(e,t){const n=wN(e),r=ke(n);if(!r)throw new Error("Unknown scale type: "+n);const i=r();return!e.domain&&_t(i.type)&&(e.domain=[0,0]),oE(e,i,t),i}function wN(e){var t=e.type,n="",r;return t===dr?dr+"-"+es:(xN(e)&&(r=e.rawDomain?e.rawDomain.length:e.domain?e.domain.length+ +(e.domainMid!=null):0,n=r===2?dr+"-":r===3?ts+"-":""),(n+t||es).toLowerCase())}function xN(e){const t=e.type;return _t(t)&&t!==Kx&&t!==Jx&&(e.scheme||e.range&&e.range.length&&e.range.every(Me))}function AN(e,t,n){if(!e.domain)return 0;n=aE(n);var r=EN(e,t.domainRaw,n);if(r>-1)return r;var i=t.domain,a=e.type,o=t.zero||t.zero===void 0&&bN(e),s,c;return i?(iE(a)&&t.padding&&i[0]!==Un(i)&&(i=SN(a,i,t.range,t.padding,t.exponent,t.constant)),(o||t.domainMin!=null||t.domainMax!=null||t.domainMid!=null)&&(s=(i=i.slice()).length-1||1,o&&(i[0]>0&&(i[0]=0),i[s]<0&&(i[s]=0)),t.domainMin!=null&&(i[0]=t.domainMin),t.domainMax!=null&&(i[s]=t.domainMax),t.domainMid!=null&&(c=t.domainMid,(c<i[0]||c>i[s])&&n.warn("Scale domainMid exceeds domain min or max.",c),i.splice(s,0,c))),e.domain(sE(a,i,n)),a===Yg&&e.unknown(t.domainImplicit?gg:void 0),t.nice&&e.nice&&e.nice(t.nice!==!0&&nE(e,t.nice)||null),i.length):0}function EN(e,t,n){return t?(e.domain(sE(e.type,t,n)),t.length):-1}function SN(e,t,n,r,i,a){var o=Math.abs(Un(n)-n[0]),s=o/(o-2*r),c=e===Ti?uv(t,null,s):e===gl?Ap(t,null,s,.5):e===pl?Ap(t,null,s,i||1):e===Ah?vI(t,null,s,a||1):xp(t,null,s);return t=t.slice(),t[0]=c[0],t[t.length-1]=c[1],t}function sE(e,t,n){if(o3(e)){var r=Math.abs(t.reduce(function(i,a){return i+(a<0?-1:a>0?1:0)},0));r!==t.length&&n.warn("Log scale domain includes zero: "+Nf(t))}return t}function _N(e,t,n){let r=t.bins;if(r&&!Qt(r)){const i=(r.start==null||r.stop==null)&&e.domain(),a=r.start==null?i[0]:r.start,o=r.stop==null?Un(i):r.stop,s=r.step;s||it("Scale bins parameter missing step property."),r=mi(a,o+s,s)}return r?e.bins=r:e.bins&&delete e.bins,e.type===Qg&&(r?!t.domain&&!t.domainRaw&&(e.domain(r),n=r.length):e.bins=e.domain()),n}function CN(e,t,n){var r=e.type,i=t.round||!1,a=t.range;if(t.rangeStep!=null)a=kN(r,t,n);else if(t.scheme&&(a=TN(r,t,n),Kt(a))){if(e.interpolator)return e.interpolator(a);it(`Scale type ${r} does not support interpolating color schemes.`)}if(a&&Sh(r))return e.interpolator(_h(Gm(a,t.reverse),t.interpolate,t.interpolateGamma));a&&t.interpolate&&e.interpolate?e.interpolate(s3(t.interpolate,t.interpolateGamma)):Kt(e.round)?e.round(i):Kt(e.rangeRound)&&e.interpolate(i?hl:Ci),a&&e.range(Gm(a,t.reverse))}function kN(e,t,n){e!==n3&&e!==Zg&&it("Only band and point scales support rangeStep.");var r=(t.paddingOuter!=null?t.paddingOuter:t.padding)||0,i=e===Zg?1:(t.paddingInner!=null?t.paddingInner:t.padding)||0;return[0,t.rangeStep*qg(n,i,r)]}function TN(e,t,n){var r=t.schemeExtent,i,a;return Qt(t.scheme)?a=_h(t.scheme,t.interpolate,t.interpolateGamma):(i=t.scheme.toLowerCase(),a=Kg(i),a||it(`Unrecognized scheme name: ${t.scheme}`)),n=e===t3?n+1:e===Qg?n-1:e===Wg||e===e3?+t.schemeCount||mN:n,Sh(e)?cE(a,r,t.reverse):Kt(a)?HB(cE(a,r),n):e===Yg?a:a.slice(0,n)}function cE(e,t,n){return Kt(e)&&(t||n)?$B(e,Gm(t||[0,1],n)):e}function Gm(e,t){return t?e.slice().reverse():e}const Vm=pt(",d");function IN(e){return e.chrom+":"+Vm(Math.floor(e.pos+1))}function lE(e){return!ft(e)&&"chrom"in e?IN(e):""+e}function RN(e,t){return e.chrom+":"+Vm(Math.floor(e.pos+1))+"-"+(e.chrom!=t.chrom?t.chrom+":":"")+Vm(Math.ceil(t.pos))}const DN="https://genomespy.app/data/genomes/";class BN{constructor(t){if(this.config=t,!this.config.contigs&&typeof this.config.name!="string")throw new Error("No name has been defined for the genome assembly!");this.chromosomes=[],this.cumulativeChromPositions=new Map,this.chromosomesByName=new Map,this.startByIndex=[],this.totalSize=0,this.config.contigs&&this.setChromSizes(this.config.contigs)}get name(){return this.config.name}async load(t){if(!this.config.contigs){this.config.baseUrl?this.baseUrl=/^http(s)?/.test(this.config.baseUrl)?this.config.baseUrl:t+"/"+this.config.baseUrl:this.baseUrl=DN;try{this.setChromSizes(FN(await Zc({baseURL:this.baseUrl}).load(`${this.config.name}/${this.name}.chrom.sizes`)))}catch(n){throw new Error(`Could not load chrom sizes: ${n.message}`)}}}hasChrPrefix(){return this.chromosomes.some(t=>t.name.startsWith("chr"))}setChromSizes(t){let n=0;this.startByIndex=[0];for(let r=0;r<t.length;r++){this.startByIndex.push(n);const i=t[r].size,a={...t[r],continuousStart:n,continuousEnd:n+i,continuousInterval:[n,n+i],index:r,number:r+1,odd:!(r&1)};this.chromosomes.push(a);const o=a.name.replace(/^chr/i,"");for(const s of["chr"+o,"CHR"+o,"Chr"+o,a.number,""+a.number,o,a.name])this.cumulativeChromPositions.set(s,n),this.chromosomesByName.set(s,a);n+=a.size}this.totalSize=n}getExtent(){return[0,this.totalSize]}toContinuous(t,n){let r=this.cumulativeChromPositions.get(t);if(r===void 0)throw new Error("Unknown chromosome/contig: "+t);return r+ +n}toChromosome(t){if(t>this.totalSize)return;t=Math.floor(t);const n=Pr(this.startByIndex,t)-1;if(n>0&&n<=this.chromosomes.length)return this.chromosomes[n-1]}toChromosomal(t){const n=this.toChromosome(t);if(n)return{chrom:n.name,pos:Math.floor(t)-n.continuousStart}}getChromosome(t){return this.chromosomesByName.get(t)}formatInterval(t){return RN(...this.toChromosomalInterval(t))}toChromosomalInterval(t){const n=this.toChromosomal(t[0]+.5),r=this.toChromosomal(t[1]-.5);return r.pos+=1,[n,r]}toContinuousInterval(t){var i;let[n,r]=t;return r||(r=n),[this.toContinuous(n.chrom,n.pos??0),this.toContinuous(r.chrom,r.pos??((i=this.chromosomesByName.get(r.chrom))==null?void 0:i.size))]}toDiscreteChromosomeIntervals(t){const n=t[0],r=t[1],i=[];if(n.chrom===r.chrom)i.push({chrom:n.chrom,startPos:n.pos,endPos:r.pos});else{const a=this.chromosomes.findIndex(s=>s.name===n.chrom),o=this.chromosomes.findIndex(s=>s.name===r.chrom);i.push({chrom:n.chrom,startPos:n.pos,endPos:this.chromosomes[a].size});for(let s=a+1;s<o;s++)i.push({chrom:this.chromosomes[s].name,startPos:0,endPos:this.chromosomes[s].size});i.push({chrom:r.chrom,startPos:0,endPos:r.pos})}return i}continuousToDiscreteChromosomeIntervals(t){return this.toDiscreteChromosomeIntervals([this.toChromosomal(t[0]),this.toChromosomal(t[1])])}parseInterval(t){const n=t.match(/^(chr[0-9A-Z]+)(?::([0-9,]+)(?:-(?:(chr[0-9A-Z]+):)?([0-9,]+))?)?$/);if(n){const r=n[1];if(n.slice(2).every(s=>s===void 0)){const s=this.getChromosome(r);return s?[s.continuousStart,s.continuousEnd]:void 0}const i=n[3]||r,a=parseInt(n[2].replace(/,/g,"")),o=n[4]!==void 0?parseInt(n[4].replace(/,/g,"")):a;return[this.toContinuous(r,a-1),this.toContinuous(i,o)]}}}function FN(e){return NI(e).filter(t=>/^chr[0-9A-Z]+$/.test(t[0])).map(([t,n])=>({name:t,size:parseInt(n)}))}function td(e){return Xt(e)&&"chrom"in e}function PN(e){return e.every(td)}class Ml extends Array{constructor(){super(),this.type=void 0}extend(t){return this}extendAll(t){if(t instanceof Ml&&t.type!=this.type)throw new Error(`Cannot combine different types of domains: ${this.type} and ${t.type}`);for(const n of t)this.extend(n);return this}extendAllWithAccessor(t,n){for(const r of t)this.extend(n(r));return this}}class jm extends Ml{constructor(){super(),this.type="quantitative"}extend(t){return t==null||Number.isNaN(t)?this:(t=+t,this.length?t<this[0]?this[0]=t:t>this[1]&&(this[1]=t):(this.push(t),this.push(t)),this)}}class uE extends Ml{constructor(){super(),this.type="ordinal",this.uniqueValues=new Set}extend(t){return t==null||Number.isNaN(t)?this:(this.uniqueValues.has(t)||(this.uniqueValues.add(t),this.push(t)),this)}}class fE extends uE{constructor(){super(),this.type="nominal"}}class MN extends Ml{constructor(t){super();let n=0;for(let r=1;r<t.length;r++)n+=Math.sign(t[r]-t[r-1]);if(Math.abs(n)!=t.length-1)throw new Error("Piecewise domain must be strictly increasing or decreasing: "+JSON.stringify(t));t.forEach(r=>this.push(r))}extend(t){if(this.includes(t))return this;throw new Error("Piecewise domains are immutable and cannot be unioned!")}}const hE={quantitative:jm,index:jm,locus:jm,nominal:fE,ordinal:uE};function dE(e,t){if(e=="quantitative"&&ON(t)){const n=new MN(t);return n.type=e,n}else if(hE[e]){const n=new hE[e];return n.type=e,t&&n.extendAll(t),n}throw new Error("Unknown type: "+e)}function ON(e){return e&&e.length>0&&e.length!=2&&e.every(t=>typeof t=="number")}function LN(e){return((e*=2)<=1?e*e:--e*(2-e)+1)/2}function NN(e){return--e*e*e+1}function zN(e){return((e*=2)<=1?e*e*e:(e-=2)*e*e+2)/2}function UN(e){return(Math.pow(2,-10*e)-.0009765625)*1.0009775171065494}function $N(e){return 1-UN(e)}function HN(e,t,n){return e*Math.pow(t/e,n)}ke("index",Hm,["continuous"]),ke("locus",aN,["continuous"]),ke("null",Ch,[]);const pE="quantitative",qm="ordinal",Wm="nominal",gE="locus",GN="index";class VN{constructor(t){Z(this,Dr);Z(this,Z0);Z(this,fc);Z(this,oi);Z(this,lf);Z(this,Q0);Z(this,V2);Z(this,uf);Z(this,ai,void 0);Z(this,uc,new Set);Z(this,Ot,void 0);this.channel=t,this.members=[],this.type=null,this.name=void 0}addEventListener(t,n){if(t!="domain")throw new Error("Unsupported event type: "+t);F(this,uc).add(n)}removeEventListener(t,n){if(t!="domain")throw new Error("Unsupported event type: "+t);F(this,uc).delete(n)}pushUnitView(t,n){var o;const r=Jg(t,n),i=r.type,a=(o=r==null?void 0:r.scale)==null?void 0:o.name;if(a){if(this.name!==void 0&&a!=this.name)throw new Error(`Shared scales have conflicting names: "${a}" vs. "${this.name}"!`);this.name=a}if(!this.type)this.type=i;else if(i!==this.type&&!xl(n))throw new Error(`Can not use shared scale for different data types: ${this.type} vs. ${i}. Use "resolve: independent" for channel ${this.channel}`);this.members.push({view:t,channel:n})}isExplicitDomain(){return!!this.getConfiguredDomain()}isDomainInitialized(){const t=F(this,Ot);if(!t)return!1;const n=t.domain();return _t(t.type)?n.length>2||n.length==2&&(n[0]!==0||n[1]!==0):n.length>0}getScaleProps(){return ds(this,"scaleProps",()=>{const t=J(this,Z0,VT).call(this);if(t===null||t.type=="null")return{type:"null"};const n={...J(this,Q0,jT).call(this,this.type),...t};n.type||(n.type=jN(this.channel,this.type));const r=J(this,fc,yp).call(this);return r&&r.length>0?n.domain=r:Vn(n.type)&&(n.domain=new fE),!n.domain&&n.domainMid!==void 0&&(n.domain=[n.domainMin??0,n.domainMax??1]),this.channel=="y"&&Vn(n.type)&&n.reverse==null&&(n.reverse=!0),n.range&&n.scheme&&delete n.scheme,!("zoom"in n)&&["index","locus"].includes(n.type)&&(n.zoom=!0),qN(n,this.channel),n})}getConfiguredDomain(){return J(this,uf,ev).call(this,t=>xl(t.channel)?void 0:t.view.getConfiguredDomain(t.channel))}getDataDomain(){return J(this,uf,ev).call(this,t=>xl(t.channel)?void 0:t.view.extractDataDomain(t.channel))}reconfigure(){if(F(this,Ot)&&F(this,Ot).type!="null"){const t=this.isDomainInitialized(),n=F(this,Ot).domain();NA(this,"scaleProps");const r=this.getScaleProps();if(oE(r,F(this,Ot)),_t(F(this,Ot).type)&&le(this,ai,J(this,lf,J2).call(this)),!t){J(this,Dr,ya).call(this);return}const i=F(this,Ot).domain();th(i,n)||(this.isZoomable()?F(this,Ot).domain(n):J(this,oi,Ho).call(this)?(F(this,Ot).domain(n),this.zoomTo(i,500)):J(this,Dr,ya).call(this))}}getScale(){if(F(this,Ot))return F(this,Ot);const t=this.getScaleProps(),n=vN(t);return le(this,Ot,n),oN(n)&&n.genome(this.getGenome()),_t(n.type)&&le(this,ai,J(this,lf,J2).call(this)),n}getDomain(){return this.getScale().domain()}getComplexDomain(){var t;return((t=this.getGenome())==null?void 0:t.toChromosomalInterval(this.getDomain()))??this.getDomain()}isZoomed(){return J(this,oi,Ho).call(this)&&th(J(this,fc,yp).call(this),this.getDomain())}isZoomable(){return J(this,oi,Ho).call(this)&&!!this.getScaleProps().zoom}zoom(t,n,r){if(!J(this,oi,Ho).call(this))return!1;const i=this.getScale(),a=i.domain();let o=[...a],s=i.invert(n);switch(this.getScaleProps().reverse&&(r=-r),"align"in i&&(s+=i.align()),i.type){case"linear":case"index":case"locus":o=mI(o,r||0),o=xp(o,s,t);break;case"log":o=bI(o,r||0),o=uv(o,s,t);break;case"pow":case"sqrt":{const c=i;o=yI(o,r||0,c.exponent()),o=Ap(o,s,t,c.exponent());break}default:throw new Error("Zooming is not implemented for: "+i.type)}return F(this,ai)&&(o=wI(o,F(this,ai)[0],F(this,ai)[1])),[0,1].some(c=>o[c]!=a[c])?(i.domain(o),J(this,Dr,ya).call(this),!0):!1}async zoomTo(t,n=!1){var s;if(kc(n)&&(n=n?700:0),!J(this,oi,Ho).call(this))throw new Error("Not a zoomable scale!");const r=this.fromComplexInterval(t),i=(s=this.members[0])==null?void 0:s.view.context.animator,a=this.getScale(),o=a.domain();if(n>0&&o.length==2){const c=o[1]-o[0],l=o[0]+c/2,u=r[1]-r[0],f=r[0]+u/2;await i.transition({duration:n,easingFunction:zN,onUpdate:h=>{const d=HN(c,u,h),p=(c-d)/(c-u),g=p*f+(1-p)*l;a.domain([g-d/2,g+d/2]),J(this,Dr,ya).call(this)}}),a.domain(r),J(this,Dr,ya).call(this)}else a.domain(r),i==null||i.requestRender(),J(this,Dr,ya).call(this)}resetZoom(){if(!J(this,oi,Ho).call(this))throw new Error("Not a zoomable scale!");const t=this.getDomain(),n=J(this,fc,yp).call(this);return[0,1].some(r=>n[r]!=t[r])?(F(this,Ot).domain(n),J(this,Dr,ya).call(this),!0):!1}getZoomLevel(){return this.isZoomable()?Lf(F(this,ai))/Lf(this.getScale().domain()):1}getGenome(){var n;if(this.type!=="locus")return;const t=(n=this.members[0].view.context.genomeStore)==null?void 0:n.getGenome();if(!t)throw new Error("No genome has been defined!");return t}invertToComplex(t){const n=this.getScale();if("invert"in n){const r=n.invert(t);return this.toComplex(r)}else throw new Error("The scale does not support inverting!")}toComplex(t){const n=this.getGenome();return n?n.toChromosomal(t):t}fromComplex(t){return td(t)?this.getGenome().toContinuous(t.chrom,t.pos):t}fromComplexInterval(t){return this.type==="locus"&&PN(t)?this.getGenome().toContinuousInterval(t):t}}ai=new WeakMap,uc=new WeakMap,Ot=new WeakMap,Dr=new WeakSet,ya=function(){for(const t of F(this,uc).values())t({type:"domain",scaleResolution:this})},Z0=new WeakSet,VT=function(){return ds(this,"mergedScaleProps",()=>{const t=this.members.map(n=>Jg(n.view,n.channel).scale).filter(n=>n!==void 0);return ed(t,"scale",["domain"])})},fc=new WeakSet,yp=function(){return this.getConfiguredDomain()??(this.type==gE?this.getGenome().getExtent():this.getDataDomain())},oi=new WeakSet,Ho=function(){const t=this.getScale().type;return _t(t)},lf=new WeakSet,J2=function(){const t=this.getScaleProps(),n=t.zoom;if(WN(n)&&Qt(n.extent))return this.fromComplexInterval(n.extent);if(n)return t.type=="locus"?this.getGenome().getExtent():F(this,Ot).domain()},Q0=new WeakSet,jT=function(t){const n=this.channel,r={};return this.isExplicitDomain()&&(r.zero=!1),wl(n)?r.nice=!this.isExplicitDomain():Ha(n)?r.scheme=t==Wm?"tableau10":t==qm?"blues":"viridis":Th(n)?r.range=n=="shape"?["circle","square","triangle-up","cross","diamond"]:[]:n=="size"?r.range=[0,400]:n=="angle"&&(r.range=[0,360]),r},V2=new WeakSet,fee=function(){return this.members.map(t=>t.view.getPathString()).join(", ")},uf=new WeakSet,ev=function(t){const n=this.members.filter(r=>!r.view.getLayoutAncestors().some(i=>!i.options.contributesToScaleDomain)).map(t).filter(r=>!!r);if(n.length)return n.reduce((r,i)=>r.extendAll(i))};function jN(e,t){if(t==GN||t==gE){if(h3(e))return t;throw new Error(`${e} does not support ${t} data type. Only positional channels do.`)}const n={x:["band","band","linear"],y:["band","band","linear"],size:[void 0,"point","linear"],opacity:[void 0,"point","linear"],fillOpacity:[void 0,"point","linear"],strokeOpacity:[void 0,"point","linear"],color:["ordinal","ordinal","linear"],fill:["ordinal","ordinal","linear"],stroke:["ordinal","ordinal","linear"],strokeWidth:[void 0,void 0,"linear"],shape:["ordinal","ordinal",void 0],dx:[void 0,void 0,"null"],dy:[void 0,void 0,"null"],angle:[void 0,void 0,"linear"]},i=["sample"].includes(e)?"null":n[e]?n[e][[Wm,qm,pE].indexOf(t)]:t==pE?"linear":"ordinal";if(i===void 0)throw new Error(`Channel "${e}" is not compatible with "${t}" data type. Use of a proper scale may be needed.`);return i}function qN(e,t){wl(t)&&e.type!=="ordinal"&&(e.range=[0,1]),t=="opacity"&&_t(e.type)&&(e.clamp=!0)}function WN(e){return Xt(e)}function Ym(e){const t=new Set;function n(r){for(const i of Object.values(r.resolutions.scale))t.add(i)}for(const r of Lt(e)){r.visit(n);for(const i of r.getDataAncestors()){if(!i.options.contributesToScaleDomain)break;n(i)}}t.forEach(r=>r.reconfigure())}function Zm(...e){for(const t of e)if(t!==void 0)return t}class YN{constructor(t){this.channel=t,this.members=[]}get scaleResolution(){var t;return(t=xn(this.members))==null?void 0:t.view.getScaleResolution(this.channel)}pushUnitView(t,n){const r=t.getScaleResolution(this.channel);if(!r)throw new Error("Cannot find a scale resolution!");if(this.scaleResolution&&r!==this.scaleResolution)throw new Error("Shared axes must have a shared scale!");this.members.push({view:t,channel:n})}getAxisProps(){return ds(this,"axisProps",()=>{const t=this.members.map(n=>{const r=n.view.mark.encoding[n.channel];return"axis"in r&&r.axis});return t.length>0&&t.some(n=>n===null)?null:ed(t.filter(n=>n!==void 0),"axis",["title"])})}getTitle(){const t=a=>{var s;const o=Jg(a.view,a.channel);if(!jn(o))return{member:a,explicitTitle:Zm("axis"in o?(s=o.axis)==null?void 0:s.title:void 0,o.title),implicitTitle:Zm(Ur(o)?o.field:void 0,kh(o)?o.expr:void 0)}},n=this.members.map(t),r=n.filter(a=>{var o;if(xl(a.member.channel)&&!a.explicitTitle){const s=$a(a.member.channel);return((o=n.find(c=>c.member.view==a.member.view&&c.member.channel==s))==null?void 0:o.explicitTitle)===void 0}return!0}),i=new Set(r.map(a=>Zm(a.explicitTitle,a.implicitTitle)).filter(Me));return i.size?[...i].join(", "):null}}const ZN={point:RL,rect:EL,rule:PL,link:UL,text:WL};class mt extends Yn{constructor(t,n,r,i,a,o){super(t,n,r,i,a,o),this.spec=t;const s=ZN[this.getMarkType()];if(s)this.mark=new s(this);else throw new Error(`No such mark: ${this.getMarkType()}`);this.resolve(),this.needsAxes={x:!0,y:!0}}render(t,n,r={}){super.render(t,n,r),this.isConfiguredVisible()&&(t.pushView(this,n),t.renderMark(this.mark,r),t.popView(this))}getMarkType(){return typeof this.spec.mark=="object"?this.spec.mark.type:this.spec.mark}resolve(t){t||(this.resolve("scale"),this.resolve("axis"));const n=this.mark.encoding;for(const[r,i]of Object.entries(n)){if(!rn(i))continue;const a=$a(i.resolutionChannel??r);if(!Ri(a)||t=="axis"&&!wl(a))continue;let o=this;for(;(o.getConfiguredOrDefaultResolution(a,t)=="forced"||o.dataParent instanceof Yn&&["shared","excluded","forced"].includes(o.dataParent.getConfiguredOrDefaultResolution(a,t)))&&o.getConfiguredOrDefaultResolution(a,t)!="excluded";)o=o.dataParent;t=="axis"&&wl(r)&&h3(a)?(o.resolutions[t][a]||(o.resolutions[t][a]=new YN(a)),o.resolutions[t][a].pushUnitView(this,r)):t=="scale"&&Ri(r)&&(o.resolutions[t][a]||(o.resolutions[t][a]=new VN(a)),o.resolutions[t][a].pushUnitView(this,r))}}getAccessor(t){return this._cache("accessor/"+t,()=>{const n=this.mark.encoding;if(n&&n[t])return this.context.accessorFactory.createAccessor(n[t])})}getFacetAccessor(t){const n=this.getAccessor("sample");return n||super.getFacetAccessor(this)}getCollector(){return this.context.dataFlow.findCollectorByKey(this)}_validateDomainQuery(t){if(xl(t))throw new Error(`getDomain(${t}), must only be called for primary channels!`);const n=this.mark.encoding[t];if(!rn(n))throw new Error("The channel has no scale, cannot get domain!");return n}getConfiguredDomain(t){const n=this._validateDomainQuery(t),r=n&&n.scale&&n.scale.domain;if(r){const i=this.getScaleResolution(n.resolutionChannel??t);return dE(n.type??"nominal",i.fromComplexInterval(r))}}extractDataDomain(t){const r=this._validateDomainQuery(t).type??"nominal",i=s=>{let c;const l=this.mark.encoding[s];if(l){const u=this.context.accessorFactory.createAccessor(l);if(u)if(c=dE(r),u.constant)c.extend(u({}));else{const f=this.getCollector();f!=null&&f.completed&&f.visitData(h=>c.extend(u(h)))}}return c};let a=i(t);const o=em[t];if(o){const s=i(o);s&&a.extendAll(s)}return a}getZoomLevel(){const t=n=>{var r;return((r=this.getScaleResolution(n))==null?void 0:r.getZoomLevel())??1};return ns.map(t).reduce((n,r)=>n*r,1)}propagateInteractionEvent(t){this.handleInteractionEvent(void 0,t,!0),t.target=this,!t.stopped&&this.handleInteractionEvent(void 0,t,!1)}getDefaultResolution(t,n){return t=="x"?"shared":"independent"}}function*Qm(e,t=[]){for(const[n,r]of e.entries())if(r instanceof Map)for(const i of Qm(r,[...t,n]))yield i;else yield[[...t,n],r]}class Ol extends at{get behavior(){return zm}constructor(t){super(),this.params=t??{type:"collect"},this.observers=[],this.facetBatches=void 0,this._init()}_init(){this._data=[],this.facetBatches=new gi([],JSON.stringify),this.facetBatches.set(void 0,this._data)}reset(){super.reset(),this._init()}handle(t){this._data.push(t)}beginBatch(t){TL(t)&&(this._data=[],this.facetBatches.set(Lt(t.facetId),this._data))}complete(){var i,a;const t=(i=this.params)==null?void 0:i.sort,n=t?fv(t.field,t.order):void 0,r=o=>{n&&o.sort(n)};if((a=this.params.groupby)!=null&&a.length){if(this.facetBatches.size>1)throw new Error("TODO: Support faceted data!");const o=this.params.groupby.map(c=>Oe(c)),s=o.length>1?Rc(this._data,...o):QN(this._data,o[0]);this.facetBatches.clear();for(const[c,l]of Qm(s))this.facetBatches.set(c,l)}for(const o of this.facetBatches.values())r(o);if(this.children.length)for(const[o,s]of this.facetBatches.entries()){if(o){const c={type:"facet",facetId:o};for(const l of this.children)l.beginBatch(c)}for(const c of s)this._propagate(c)}super.complete();for(const o of this.observers)o(this)}getData(){switch(this._checkStatus(),this.facetBatches.size){case 0:return[];case 1:return[...this.facetBatches.values()][0];default:{const t=this.facetBatches;return{[Symbol.iterator]:function*(){for(const r of t.values())for(let i=0;i<r.length;i++)yield r[i]}}}}}visitData(t){this._checkStatus();for(const n of this.facetBatches.values())for(let r=0;r<n.length;r++)t(n[r])}getItemCount(){let t=0;for(const n of this.facetBatches.values())t+=n.length;return t}_checkStatus(){if(!this.completed)throw new Error("Data propagation is not completed! No data are available.")}}function QN(e,t){const n=new Map;for(let r=0,i=e.length;r<i;r++){const a=e[r],o=t(a);let s=n.get(o);s||(s=[],n.set(o,s)),s.push(a)}return n}class Ll{constructor(){this.ids=[],this.values=[],this.length=0}clear(){this.length=0}push(t,n){let r=this.length++;for(;r>0;){const i=r-1>>1,a=this.values[i];if(n>=a)break;this.ids[r]=this.ids[i],this.values[r]=a,r=i}this.ids[r]=t,this.values[r]=n}pop(){if(this.length===0)return;const t=this.ids[0];if(this.length--,this.length>0){const n=this.ids[0]=this.ids[this.length],r=this.values[0]=this.values[this.length],i=this.length>>1;let a=0;for(;a<i;){let o=(a<<1)+1;const s=o+1;let c=this.ids[o],l=this.values[o];const u=this.values[s];if(s<this.length&&u<l&&(o=s,c=this.ids[s],l=u),l>=r)break;this.ids[a]=c,this.values[a]=l,a=o}this.ids[a]=n,this.values[a]=r}return t}peek(){if(this.length!==0)return this.ids[0]}peekValue(){if(this.length!==0)return this.values[0]}shrink(){this.ids.length=this.values.length=this.length}}class XN extends at{get behavior(){return mr}constructor(t){super(),this.params=t,this.startAccessor=Oe(t.start),this.endAccessor=Oe(t.end),this.chromAccessor=t.chrom?Oe(t.chrom):n=>{},this.weightAccessor=t.weight?Oe(t.weight):n=>1,this.as={coverage:t.as||"coverage",start:t.asStart||t.start,end:t.asEnd||t.end,chrom:t.asChrom||t.chrom},this.createSegment=new Function("start","end","coverage","chrom","return {"+Object.entries(this.as).filter(([n,r])=>r).map(([n,r])=>`${JSON.stringify(r)}: ${n}`).join(", ")+"};"),this.ends=new Ll}reset(){super.reset(),this.initialize()}initialize(){const t=this.as.coverage,n=this.as.end,r=this.as.chrom,i=this.startAccessor,a=this.endAccessor,o=this.chromAccessor,s=this.weightAccessor;let c,l,u,f=0,h;const d=this.ends;d.clear();const p=(b,y,w)=>{if(b==y)return;let A=!1;c&&(c[t]===w?(c[n]=y,A=!0):c[t]!=0&&this._propagate(c)),A||(c=this.createSegment(b,y,w,u))},g=()=>{let b=0;for(;(b=d.peekValue())!==void 0;)p(h,b,f),h=b,f-=d.pop();h=void 0,c&&(this._propagate(c),c=void 0)};this.handle=b=>{const y=i(b);let w=0;for(;(w=d.peekValue())!==void 0&&w<y;)p(h,w,f),h=w,f-=d.pop();if(r){let x=o(b);x!==l&&(g(),u=x,l=u)}h!==void 0&&p(h,y,f),h=y;const A=s(b);f+=A,d.push(A,a(b))},this.complete=()=>{g(),super.complete()},this.beginBatch=b=>{g(),l=void 0,super.beginBatch(b)}}}function KN(e,t,n=0,r=e.length){const i=new Ll,a=r-n;let o;for(o=0;o<t&&o<a;o++)i.push(o,e[n+o]);for(;o<a;o++){const l=e[n+o];l>=i.peekValue()&&(i.push(o,l),i.pop())}const s=[];let c;for(;(c=i.pop())!==void 0;)s.push(n+c);return s.reverse()}class JN{constructor(t,n=-1/0,r=1/0){this.maxSize=t,this.lowerLimit=n,this.upperLimit=r;const i=this.maxSize*2+1;this.lowerLimits=new Float64Array(i),this.upperLimits=new Float64Array(i),this.lowerChildren=new Int32Array(i),this.upperChildren=new Int32Array(i),this.reset()}reset(){this.lowerLimits.fill(0),this.upperLimits.fill(0),this.lowerChildren.fill(0),this.upperChildren.fill(0),this.n=1,this.lowerLimits[0]=this.lowerLimit,this.upperLimits[0]=this.upperLimit}_findSlot(t,n,r=0){if(t>=this.lowerLimits[r]&&n<=this.upperLimits[r]){const i=this.lowerChildren[r];if(i){const a=this._findSlot(t,n,i);return a>=0?a:this._findSlot(t,n,this.upperChildren[r])}else return r}else return-1}reserve(t,n){if(n-t<=0)throw new Error("Cannot reserve an empty or negative-size slot!");if(this.n+1>this.lowerLimits.length)return!1;const r=this._findSlot(t,n);if(r<0)return!1;const i=this.n++,a=this.n++;return this.lowerLimits[i]=this.lowerLimits[r],this.upperLimits[i]=t,this.lowerLimits[a]=n,this.upperLimits[a]=this.upperLimits[r],this.lowerChildren[r]=i,this.upperChildren[r]=a,!0}}class ez extends at{get behavior(){return zm}constructor(t,n){if(super(),this.params=t,this._data=[],this.channel=t.channel??"x",!["x","y"].includes(this.channel))throw new Error("Invalid channel: "+this.channel);this.posAccessor=Oe(this.params.pos),this.posBisector=Uf(this.posAccessor),this.scoreAccessor=Oe(this.params.score),this.widthAccessor=Oe(this.params.width),this.laneAccessor=this.params.lane?Oe(this.params.lane):i=>0,this.padding=this.params.padding??0,this.reservationMaps=new Map,this.resolution=n.getScaleResolution(this.channel);const r=()=>this._filterAndPropagate();this.schedule=()=>n.context.animator.requestTransition(r),this.resolution.addEventListener("domain",i=>this.schedule()),n._addBroadcastHandler("layoutComputed",()=>this.schedule())}complete(){const t=this.posAccessor;this._data.sort((n,r)=>t(n)-t(r)),this._scores=this._data.map(this.scoreAccessor);for(const n of new Set(this._data.map(this.laneAccessor)))this.reservationMaps.set(n,new JN(200));this.schedule(),super.complete()}_filterAndPropagate(){var o;super.reset();const t=this.resolution.getScale(),n=(o=this.resolution.members[0].view.coords)==null?void 0:o[this.channel=="x"?"width":"height"];if(!n)return;for(const s of this.reservationMaps.values())s.reset();const r=t.domain(),i=70,a=KN(this._scores,i,this.posBisector.left(this._data,r[0]),this.posBisector.right(this._data,r[1]));for(const s of a){const c=this._data[s],l=t(this.posAccessor(c))*n,u=this.widthAccessor(c)/2+this.padding;this.reservationMaps.get(this.laneAccessor(c)).reserve(l-u,l+u)&&this._propagate(c)}super.complete()}reset(){super.reset(),this._data=[],this.groups=new Map}handle(t){this._data.push(t)}}class tz extends at{constructor(t){super(),this.params=t,this.predicate=void 0}initialize(){this.predicate=ch(this.params.expr,this.getGlobalObject())}handle(t){this.predicate(t)&&this._propagate(t)}}class nz extends at{get behavior(){return mr}constructor(t){super();const n=t.index;if(t.fields){const r=Lt(t.fields).map(a=>Oe(a)),i=Lt(t.as||t.fields);if(r.length!==i.length)throw new Error(`Lengths of "fields" (${r.length}), and "as" (${i.length}) do not match!`);this.handle=a=>{const o=r.map((c,l)=>c(a)??[]),s=o[0].length;for(let c=0;c<s;c++){const l=Object.assign({},a);for(let u=0;u<r.length;u++)l[i[u]]=c<o[u].length?o[u][c]:null;n&&(l[n]=c),this._propagate(l)}}}else this.handle=r=>{for(let i=0;i<r.length;i++){const a=Object.assign({},r[i]);n&&(a[n]=i),this._propagate(a)}}}}const rz="0".charCodeAt(0);function*iz(e,t=","){const n=t.charCodeAt(0);let r=0;for(let i=0;i<e.length;i++){const a=e.charCodeAt(i);a==n?(yield r,r=0):r=r*10+a-rz}yield r}class az extends at{get behavior(){return mr}constructor(t){super();const n=Oe(t.exons??"exons"),r=Oe(t.start??"start"),[i,a]=t.as||["exonStart","exonEnd"];this.handle=o=>{let s=r(o),c=s,l=!0;const u=n(o);for(const f of iz(u)){if(l)c=s+f;else{s=c+f;const h=Object.assign({},o);h[i]=c,h[a]=s,this._propagate(h)}l=!l}}}}class oz extends at{get behavior(){return mr}constructor(t){super();const 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Li}constructor(t){super(),this.params=t}reset(){super.reset(),this.initialize()}initialize(){const t=this.params,n=t.as||"lane",r=ft(t.spacing)?t.spacing:1,i=Oe(t.start),a=Oe(t.end);if(!t.preference!=!t.preferredOrder)throw new Error('Must specify both "preference" and "preferredOrder"');if(t.preference){const o=new Float64Array(uz),s=Oe(t.preference),c=t.preferredOrder;let l=1/0;this.handle=u=>{const f=i(u);f<l&&o.fill(-1/0),l=f;const h=c.indexOf(s(u));let d=-1;if(h>=0&&o[h]<f)d=h;else{const p=i(u);for(d=0;d<o.length&&!(o[d]<p);d++);if(d>=o.length)throw new Error("Out of lanes!")}o[d]=a(u)+r,u[n]=d,this._propagate(u)}}else{const o=new Ll,s=new Ll;let c=-1/0,l=0;this.handle=u=>{const f=i(u);for(;o.length&&(o.peekValue()<=f||f<c);){const d=o.pop();s.push(d,d)}c=f;let h=s.pop();h===void 0&&(h=l++),u[n]=h,this._propagate(u),o.push(h,a(u)+r)}}}}class hz extends at{get behavior(){return mr}constructor(t){if(super(),t.as&&t.as.length!=t.fields.length)throw new Error('"fields" and "as" have unequal lengths!');const n=t.fields.map(i=>Oe(i)),r=t.as?t.as:n.map(Vo);this.handle=i=>{const a={};for(let o=0;o<n.length;o++)a[r[o]]=n[o](i);this._propagate(a)}}}class dz extends at{get behavior(){return Li}constructor(t){super();const n=new RegExp(t.regex),r=typeof t.as=="string"?[t.as]:t.as,i=Oe(t.field);this.handle=a=>{const o=i(a);if(Me(o)){const s=o.match(n);if(s){if(s.length-1!=r.length)throw new Error('The number of RegEx groups and the length of "as" do not match!');for(let c=0;c<r.length;c++)a[r[c]]=s[c+1]}else if(t.skipInvalidInput)for(let c=0;c<r.length;c++)a[r[c]]=void 0;else throw new Error(`"${o}" does not match the given regex: ${n.toString()}`)}else if(!t.skipInvalidInput)throw new Error(`Trying to match a non-string field. 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1696
1696
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`+g.join(`,
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1697
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};`)},u=h=>{o||l(h);for(let d=0;d<o.length;d++){const[p,g]=o[d],b=c(h,p,g);this._propagate(b)}},f=h=>{l(h),u(h),this.handle=u};this.handle=f,this.beginBatch=h=>{qA(h)&&(this.handle=f),super.beginBatch(h)}}}class gz extends at{get behavior(){return Li}constructor(t){super(),this.params=t,this.buffer=[]}reset(){this.buffer=[]}handle(t){this.buffer.push(t)}complete(){const t=this.params,n=t.as||["y0","y1"],r=t.sort?fv(t.sort.field,t.sort.order):void 0,i=t.field?Oe(t.field):()=>1,a=t.groupby.map(u=>Oe(u)),o=JI(this.buffer,u=>a.map(f=>f(u)).join()).map(u=>u[1]);let s=u=>!0;if(t.baseField){const u=Oe(t.baseField);s=f=>u(f)!==null}let c,l;switch(t.offset){case"normalize":c=(u,f)=>u/f,l=(u,f)=>Gf(u,f);break;case"center":c=(u,f)=>u-f/2,l=(u,f)=>Gf(u,f);break;case"information":{const u=Math.log2(t.cardinality??4);c=(f,h)=>f/h,l=(f,h)=>{const p=Gf(f,w=>+!s(w)),g=Gf(f,h),b=g-p;let y=0;for(let w=0;w<f.length;w++){const A=f[w];if(s(A)){const x=h(A)/b;y-=x*Math.log2(x)}}return b/(u-(y+0))*(b/g)}}break;default:c=(u,f)=>u,l=(u,f)=>1}for(const u of o){r&&u.sort(r);const f=l(u,i);let h=0;for(const d of u){const p=h+i(d);s(d)&&(d[n[0]]=c(h,f),d[n[1]]=c(p,f),this._propagate(d),h=p)}}super.complete()}}class mz extends at{get behavior(){return mr}constructor(t){super();const n=Oe(t.field??"sequence"),[r,i]=t.as??["pos","sequence"];this.handle=a=>{const o=Object.assign({},a,{[i]:"",[r]:0}),s=n(a);for(let c=0;c<s.length;c++){const l=Object.assign({},o);l[r]=c,l[i]=s.charAt(c),this._propagate(l)}}}}class bz extends at{get behavior(){return mr}constructor(t){super(),this.params=t,this.buffer=[]}reset(){this.buffer=[]}handle(t){this.buffer.push(t)}complete(){const n=this.params.groupby,r=n.map(a=>Oe(a)),i=Rc(this.buffer,...r);for(const[a,o]of Qm(i)){const s={count:o.length};for(let c=0;c<n.length;c++)s[n[c]]=a[c];this._propagate(s)}super.complete()}}const yz="_uniqueId",yE=1e4,vE=[null];class wE extends at{get behavior(){return Li}constructor(t){super(),this.params=t,this.as=t.as??yz,this._blocks=[],this._usedBlocks=0,this._id=-1}initialize(){}reset(){super.reset(),this._usedBlocks=0,this._id=-1}handle(t){t[this.as]=this._nextId(),this._propagate(t)}_nextId(){return++this._id%yE==0&&(this._id=this._getBlock()*yE),this._id}_getBlock(){return this._usedBlocks<this._blocks.length?this._blocks[this._usedBlocks++]:this._reserveBlock()}_reserveBlock(){const t=vE.length;return vE[t]=this,this._blocks.push(t),this._usedBlocks++,t}}const xE={aggregate:bz,collect:Ol,coverage:XN,filterScoredLabels:ez,filter:tz,flatten:nz,flattenCompressedExons:az,flattenDelimited:oz,flattenSequence:mz,formula:cz,identifier:wE,linearizeGenomicCoordinate:mE,measureText:lz,pileup:fz,project:hz,regexExtract:dz,regexFold:pz,sample:WA,stack:gz};function vz(e,t){const n=xE[e.type];if(n)return new n(e,t);throw new Error("Unknown transform: "+e.type)}function AE(e){if(!_E(e)&&!SE(e))return;const t={...e.format};if(t.type??(t.type=SE(e)&&wz(e.url)),t.parse??(t.parse="auto"),!t.type)throw new Error("Format for the data source was not defined and it could not be inferred: "+JSON.stringify(e));return t}function wz(e){var t;if(Array.isArray(e)&&(e=e[0]),e)return(t=e.match(/\.(csv|tsv|json)/))==null?void 0:t[1]}const EE=e=>typeof e!="object"?xz:Az,xz=e=>({data:e}),Az=e=>e;function SE(e){return"url"in e}class ms extends at{get identifier(){}handle(t){throw new Error("Source does not handle incoming data!")}async load(){}}function _E(e){return"values"in e}class Ez extends ms{constructor(t,n){var r;if(super(),this.params=t,typeof t.values=="string"&&!((r=t==null?void 0:t.format)!=null&&r.type))throw new Error("Data format type (csv, dsv, ...) must be specified if a string is provided!")}loadSynchronously(){const t=this.params.values;let n=[],r=i=>i;if(Array.isArray(t))t.length>0&&(n=t,r=EE(t[0]));else if(typeof t=="object")n=[t];else if(typeof t=="string")n=dw(t,AE(this.params));else throw new Error('"values" in data configuration is not an array, object, or a string!');this.reset(),this.beginBatch({type:"file"});for(const i of n)this._propagate(r(i));this.complete()}async load(){this.loadSynchronously()}}function Sz(e){return"url"in e}class _z extends ms{constructor(t,n){super(),this.params=t,this.baseUrl=n==null?void 0:n.getBaseUrl()}get identifier(){return JSON.stringify({params:this.params,baseUrl:this.baseUrl})}async load(){const t=this.params.url,n=Array.isArray(t)?t:[t],r=async a=>Zc({baseURL:this.baseUrl}).load(a).catch(o=>{throw new Error(`Cannot fetch: ${this.baseUrl}${a}: ${o.message}`)}),i=(a,o)=>{try{const s=dw(a,AE(this.params));this.beginBatch({type:"file",url:o});for(const c of s)this._propagate(c)}catch(s){throw new Error(`Cannot parse: ${o}: ${s.message}`)}};this.reset(),await Promise.all(n.map(a=>r(a).then(i))),this.complete()}}function Cz(e){return"sequence"in e}class kz extends ms{constructor(t,n){if(super(),this.sequence=t.sequence,!("start"in this.sequence))throw new Error("'start' is missing from sequence parameters!");if(!("stop"in this.sequence))throw new Error("'stop' is missing from sequence parameters!")}loadSynchronously(){const t=this.sequence.as||"data",n=this.sequence.step||1,r=this.sequence.stop;this.reset(),this.beginBatch({type:"file"});for(let i=this.sequence.start;i<r;i+=n)this._propagate({[t]:i});this.complete()}async load(){this.loadSynchronously()}}class Xm extends ms{constructor(n,r){super();zn(this,"initializedPromise",Promise.resolve());if(this.view=n,r){if(r!=="x"&&r!=="y")throw new Error(`Invalid channel specified for the lazy data source: ${r}. Must be either "x" or "y"`)}else throw new Error('No channel has been specified for the lazy data source. Must be either "x" or "y".');if(this.channel=r,this.scaleResolution=this.view.getScaleResolution(r),!this.scaleResolution){const a=[`The lazy data source cannot find a resolved scale for channel "${r}".`];throw this.view instanceof mt||a.push('Make sure the view has a "shared" scale resolution as it is not a unit view.'),new Error(a.join(" "))}const i=()=>{this.view.isVisible()&&this.onDomainChanged(this.scaleResolution.getDomain(),this.scaleResolution.getComplexDomain())};this.scaleResolution.addEventListener("domain",i),this.view.context.addBroadcastListener("layoutComputed",i)}getAxisLength(){const n=this.scaleResolution.members.map(r=>{var i;return(i=r.view.coords)==null?void 0:i[this.channel==="x"?"width":"height"]}).filter(r=>r>0);return n.length?n.reduce((r,i)=>Math.min(r,i),1e4):0}get genome(){return this.scaleResolution.getGenome()}async onDomainChanged(n,r){}setLoadingStatus(n){this.view.context.setDataLoadingStatus(this.view,n)}requestRender(){this.view.context.animator.requestRender()}async load(){this.reset(),this.complete()}publishData(n){this.reset(),this.beginBatch({type:"file"});for(const r of n)for(const i of r)this._propagate(i);this.complete(),Ym(this.view),this.requestRender()}}class Tz extends Xm{constructor(n,r){const i={axis:{},...n};super(r,i.channel);zn(this,"ticks",[]);this.params=n}async onDomainChanged(){const n=this.scaleResolution.getScale(),r=this.params.axis,i=this.getAxisLength(),a=l=>25+60*pg(100,700,l),o=ft(r.tickCount)?r.tickCount:Math.round(i/a(i)),s=nE(n,o,r.tickMinStep),c=r.values?rE(n,r.values,s):sN(n,s);if(!th(c,this.ticks)){this.ticks=c;const l=lN(n,o,r.format);this.publishData([c.map(u=>({value:u,label:l(u)}))])}}}class Iz extends Xm{constructor(t,n){super(n,t.channel)}async load(){this.publishData([this.genome.chromosomes])}}function Xa(e,t){return!t||/^(data:|([A-Za-z]+:)?\/\/)/.test(e)||e.startsWith("/")?e:(t.endsWith("/")||(t+="/"),t+e)}function bs(e,t,n=!0){let r,i=o=>{};return function(...s){return new Promise((c,l)=>{const u=()=>{clearTimeout(r),i=f=>{},c(e(...s))};n&&i("debounced"),clearTimeout(r),i=l,r=window.setTimeout(u,t)})}}class Nl extends Xm{constructor(){super(...arguments);Z(this,hc,new AbortController);Z(this,ff,[0,0]);zn(this,"params")}setupDebouncing(n){n.debounce>0&&(n.debounceMode=="domain"?this.onDomainChanged=bs(this.onDomainChanged.bind(this),n.debounce,!1):n.debounceMode=="window"&&(this.loadInterval=bs(this.loadInterval.bind(this),n.debounce,!1)))}async onDomainChanged(n){var a;const r=((a=this.params)==null?void 0:a.windowSize)??-1;if(n[1]-n[0]>r)return;const i=this.quantizeInterval(n,r);this.checkAndUpdateLastInterval(i)&&(await this.initializedPromise,this.loadInterval(i))}async loadInterval(n){}async discretizeAndLoad(n,r){F(this,hc).abort(),this.setLoadingStatus(!0),le(this,hc,new AbortController);const i=F(this,hc).signal,a=this.genome.continuousToDiscreteChromosomeIntervals(n);try{const o=await Promise.all(a.map(async s=>r(s,i)));if(!i.aborted)return this.setLoadingStatus(!1),o}catch(o){if(!i.aborted)throw this.setLoadingStatus(!1),o}}quantizeInterval(n,r){return[Math.max(Math.floor(n[0]/r-1)*r,0),Math.min(Math.ceil(n[1]/r+1)*r,this.genome.totalSize)]}checkAndUpdateLastInterval(n){return th(F(this,ff),n)?!1:(le(this,ff,n),!0)}}hc=new WeakMap,ff=new WeakMap;class Rz extends Nl{constructor(t,n){const r={channel:"x",windowSize:7e3,debounce:200,debounceMode:"window",...t};if(super(n,r.channel),this.params=r,!this.params.url)throw new Error("No URL provided for IndexedFastaSource");this.setupDebouncing(this.params),this.initializedPromise=new Promise(i=>{Promise.all([Promise.resolve().then(()=>d6),Promise.resolve().then(()=>UY),Promise.resolve().then(()=>hu)]).then(([{Buffer:a},{IndexedFasta:o},{RemoteFile:s}])=>{typeof window<"u"&&(window.Buffer??(window.Buffer=a));const c=l=>new s(Xa(l,this.view.getBaseUrl()));this.fasta=new o({fasta:c(this.params.url),fai:c(this.params.indexUrl??this.params.url+".fai")}),i()})})}async loadInterval(t){const n=await this.discretizeAndLoad(t,async(r,i)=>this.fasta.getSequence(r.chrom,r.startPos,r.endPos,{signal:i}).then(a=>({chrom:r.chrom,start:r.startPos,sequence:a})));n&&this.publishData([n])}}class Dz extends Nl{constructor(n,r){const i={pixelsPerBin:2,channel:"x",debounce:200,debounceMode:"window",...n};super(r,i.channel);Z(this,dc,[]);Z(this,pc,void 0);if(this.params=i,!this.params.url)throw new Error("No URL provided for BigWigSource");this.setupDebouncing(this.params),this.initializedPromise=new Promise(a=>{Promise.all([Promise.resolve().then(()=>fk),Promise.resolve().then(()=>hu)]).then(([{BigWig:o},{RemoteFile:s}])=>{le(this,pc,new o({filehandle:new s(Xa(this.params.url,this.view.getBaseUrl()))})),F(this,pc).getHeader().then(c=>{le(this,dc,c.zoomLevels.map(l=>l.reductionLevel).reverse()),F(this,dc).push(1),a()})})})}async onDomainChanged(n){await this.initializedPromise;const r=this.getAxisLength()||700,i=Bz(n,r,F(this,dc)),a=Math.max(i*r,5e3),o=this.quantizeInterval(n,a);this.checkAndUpdateLastInterval(o)&&this.loadInterval(o,i)}async loadInterval(n,r){const i=.5/r/this.params.pixelsPerBin,a=await this.discretizeAndLoad(n,(o,s)=>F(this,pc).getFeatures(o.chrom,o.startPos,o.endPos,{scale:i,signal:s}).then(c=>c.map(l=>({chrom:o.chrom,start:l.start,end:l.end,score:l.score}))));a&&this.publishData(a)}}dc=new WeakMap,pc=new WeakMap;function Bz(e,t,n){const r=(e[1]-e[0])/t;return n.find(i=>i<r)??n.at(-1)}class Fz extends Nl{constructor(n,r){const i={channel:"x",windowSize:1e6,debounce:200,debounceMode:"window",...n};super(r,i.channel);zn(this,"parser");zn(this,"bbi");zn(this,"parseLine");if(this.params=i,!this.params.url)throw new Error("No URL provided for BigBedSource");this.setupDebouncing(this.params),this.initializedPromise=new Promise(a=>{Promise.all([Promise.resolve().then(()=>MK),Promise.resolve().then(()=>fk),Promise.resolve().then(()=>hu)]).then(([o,{BigBed:s},{RemoteFile:c}])=>{const l=o.default;this.bbi=new s({filehandle:new c(Xa(this.params.url,this.view.getBaseUrl()))}),this.bbi.getHeader().then(async u=>{this.parser=new l({autoSql:u.autoSql});try{const f=Pz(this.parser);this.parseLine=(h,d)=>f(h,d.start,d.end,d.rest)}catch{this.parseLine=(h,d)=>this.parser.parseLine(`${h} ${d.start} ${d.end} ${d.rest}`)}a()})})})}async loadInterval(n){const r=await this.discretizeAndLoad(n,async(i,a)=>this.bbi.getFeatures(i.chrom,i.startPos,i.endPos,{signal:a}).then(o=>o.map(s=>this.parseLine(i.chrom,s))));r&&this.publishData(r)}}function Pz(e){const t=e.autoSql.fields.filter(y=>y.type).slice(3);let n=0,r="",i=0,a={};const o=" ",s=o.charCodeAt(0),c="0".charCodeAt(0),l="-".charCodeAt(0);function u(){let y=r.indexOf(o,n);y<0&&(y=i);const w=r.substring(n,y);return n=y+1,w}function f(){let y=0,w=r.charCodeAt(n),A=1;w===l&&(A=-1,n++,w=r.charCodeAt(n));do{if(w===s){n++;break}y=y*10+w-c,w=r.charCodeAt(++n)}while(n<i);return y*A}const h=t.map(y=>{const{name:w,type:A}=y;if(["ubyte","int","uint"].includes(A))return()=>{a[w]=f()};if(y.isNumeric)return()=>{a[w]=Number(u())};if(["char","string","lstring"].includes(A))return()=>{a[w]=u()};throw new Error("Unsupported type: "+A)}),d=t.map(y=>`"${y.name}": ${y.isNumeric?"0":"emptyString"}`),p=new Function(`
|
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1698
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+
};`)},u=h=>{o||l(h);for(let d=0;d<o.length;d++){const[p,g]=o[d],b=c(h,p,g);this._propagate(b)}},f=h=>{l(h),u(h),this.handle=u};this.handle=f,this.beginBatch=h=>{qA(h)&&(this.handle=f),super.beginBatch(h)}}}class gz extends at{get behavior(){return Li}constructor(t){super(),this.params=t,this.buffer=[]}reset(){this.buffer=[]}handle(t){this.buffer.push(t)}complete(){const t=this.params,n=t.as||["y0","y1"],r=t.sort?fv(t.sort.field,t.sort.order):void 0,i=t.field?Oe(t.field):()=>1,a=t.groupby.map(u=>Oe(u)),o=JI(this.buffer,u=>a.map(f=>f(u)).join()).map(u=>u[1]);let s=u=>!0;if(t.baseField){const u=Oe(t.baseField);s=f=>u(f)!==null}let c,l;switch(t.offset){case"normalize":c=(u,f)=>u/f,l=(u,f)=>Gf(u,f);break;case"center":c=(u,f)=>u-f/2,l=(u,f)=>Gf(u,f);break;case"information":{const u=Math.log2(t.cardinality??4);c=(f,h)=>f/h,l=(f,h)=>{const p=Gf(f,w=>+!s(w)),g=Gf(f,h),b=g-p;let y=0;for(let w=0;w<f.length;w++){const A=f[w];if(s(A)){const x=h(A)/b;y-=x*Math.log2(x)}}return b/(u-(y+0))*(b/g)}}break;default:c=(u,f)=>u,l=(u,f)=>1}for(const u of o){r&&u.sort(r);const f=l(u,i);let h=0;for(const d of u){const p=h+i(d);s(d)&&(d[n[0]]=c(h,f),d[n[1]]=c(p,f),this._propagate(d),h=p)}}super.complete()}}class mz extends at{get behavior(){return mr}constructor(t){super();const n=Oe(t.field??"sequence"),[r,i]=t.as??["pos","sequence"];this.handle=a=>{const o=Object.assign({},a,{[i]:"",[r]:0}),s=n(a);for(let c=0;c<s.length;c++){const l=Object.assign({},o);l[r]=c,l[i]=s.charAt(c),this._propagate(l)}}}}class bz extends at{get behavior(){return mr}constructor(t){super(),this.params=t,this.buffer=[]}reset(){this.buffer=[]}handle(t){this.buffer.push(t)}complete(){const n=this.params.groupby,r=n.map(a=>Oe(a)),i=Rc(this.buffer,...r);for(const[a,o]of Qm(i)){const s={count:o.length};for(let c=0;c<n.length;c++)s[n[c]]=a[c];this._propagate(s)}super.complete()}}const yz="_uniqueId",yE=1e4,vE=[null];class wE extends at{get behavior(){return Li}constructor(t){super(),this.params=t,this.as=t.as??yz,this._blocks=[],this._usedBlocks=0,this._id=-1}initialize(){}reset(){super.reset(),this._usedBlocks=0,this._id=-1}handle(t){t[this.as]=this._nextId(),this._propagate(t)}_nextId(){return++this._id%yE==0&&(this._id=this._getBlock()*yE),this._id}_getBlock(){return this._usedBlocks<this._blocks.length?this._blocks[this._usedBlocks++]:this._reserveBlock()}_reserveBlock(){const t=vE.length;return vE[t]=this,this._blocks.push(t),this._usedBlocks++,t}}const xE={aggregate:bz,collect:Ol,coverage:XN,filterScoredLabels:ez,filter:tz,flatten:nz,flattenCompressedExons:az,flattenDelimited:oz,flattenSequence:mz,formula:cz,identifier:wE,linearizeGenomicCoordinate:mE,measureText:lz,pileup:fz,project:hz,regexExtract:dz,regexFold:pz,sample:WA,stack:gz};function vz(e,t){const n=xE[e.type];if(n)return new n(e,t);throw new Error("Unknown transform: "+e.type)}function AE(e){if(!_E(e)&&!SE(e))return;const t={...e.format};if(t.type??(t.type=SE(e)&&wz(e.url)),t.parse??(t.parse="auto"),!t.type)throw new Error("Format for the data source was not defined and it could not be inferred: "+JSON.stringify(e));return t}function wz(e){var t;if(Array.isArray(e)&&(e=e[0]),e)return(t=e.match(/\.(csv|tsv|json)/))==null?void 0:t[1]}const EE=e=>typeof e!="object"?xz:Az,xz=e=>({data:e}),Az=e=>e;function SE(e){return"url"in e}class ms extends at{get identifier(){}handle(t){throw new Error("Source does not handle incoming data!")}async load(){}}function _E(e){return"values"in e}class Ez extends ms{constructor(t,n){var r;if(super(),this.params=t,typeof t.values=="string"&&!((r=t==null?void 0:t.format)!=null&&r.type))throw new Error("Data format type (csv, dsv, ...) must be specified if a string is provided!")}loadSynchronously(){const t=this.params.values;let n=[],r=i=>i;if(Array.isArray(t))t.length>0&&(n=t,r=EE(t[0]));else if(typeof t=="object")n=[t];else if(typeof t=="string")n=dw(t,AE(this.params));else throw new Error('"values" in data configuration is not an array, object, or a string!');this.reset(),this.beginBatch({type:"file"});for(const i of n)this._propagate(r(i));this.complete()}async load(){this.loadSynchronously()}}function Sz(e){return"url"in e}class _z extends ms{constructor(t,n){super(),this.params=t,this.baseUrl=n==null?void 0:n.getBaseUrl()}get identifier(){return JSON.stringify({params:this.params,baseUrl:this.baseUrl})}async load(){const t=this.params.url,n=Array.isArray(t)?t:[t],r=async a=>Zc({baseURL:this.baseUrl}).load(a).catch(o=>{throw new Error(`Cannot fetch: ${this.baseUrl}${a}: ${o.message}`)}),i=(a,o)=>{try{const s=dw(a,AE(this.params));this.beginBatch({type:"file",url:o});for(const c of s)this._propagate(c)}catch(s){throw new Error(`Cannot parse: ${o}: ${s.message}`)}};this.reset(),await Promise.all(n.map(a=>r(a).then(i))),this.complete()}}function Cz(e){return"sequence"in e}class kz extends ms{constructor(t,n){if(super(),this.sequence=t.sequence,!("start"in this.sequence))throw new Error("'start' is missing from sequence parameters!");if(!("stop"in this.sequence))throw new Error("'stop' is missing from sequence parameters!")}loadSynchronously(){const t=this.sequence.as||"data",n=this.sequence.step||1,r=this.sequence.stop;this.reset(),this.beginBatch({type:"file"});for(let i=this.sequence.start;i<r;i+=n)this._propagate({[t]:i});this.complete()}async load(){this.loadSynchronously()}}class Xm extends ms{constructor(n,r){super();zn(this,"initializedPromise",Promise.resolve());if(this.view=n,r){if(r!=="x"&&r!=="y")throw new Error(`Invalid channel specified for the lazy data source: ${r}. Must be either "x" or "y"`)}else throw new Error('No channel has been specified for the lazy data source. Must be either "x" or "y".');if(this.channel=r,this.scaleResolution=this.view.getScaleResolution(r),!this.scaleResolution){const a=[`The lazy data source cannot find a resolved scale for channel "${r}".`];throw this.view instanceof mt||a.push('Make sure the view has a "shared" scale resolution as it is not a unit view.'),new Error(a.join(" "))}const i=()=>{this.view.isVisible()&&this.onDomainChanged(this.scaleResolution.getDomain(),this.scaleResolution.getComplexDomain())};this.scaleResolution.addEventListener("domain",i),this.view.context.addBroadcastListener("layoutComputed",i)}getAxisLength(){const n=this.scaleResolution.members.map(r=>{var i;return(i=r.view.coords)==null?void 0:i[this.channel==="x"?"width":"height"]}).filter(r=>r>0);return n.length?n.reduce((r,i)=>Math.min(r,i),1e4):0}get genome(){return this.scaleResolution.getGenome()}async onDomainChanged(n,r){}setLoadingStatus(n){this.view.context.setDataLoadingStatus(this.view,n)}requestRender(){this.view.context.animator.requestRender()}async load(){this.reset(),this.complete()}publishData(n){this.reset(),this.beginBatch({type:"file"});for(const r of n)for(const i of r)this._propagate(i);this.complete(),Ym(this.view),this.requestRender()}}class Tz extends Xm{constructor(n,r){const i={axis:{},...n};super(r,i.channel);zn(this,"ticks",[]);this.params=n}async onDomainChanged(){const n=this.scaleResolution.getScale(),r=this.params.axis,i=this.getAxisLength(),a=l=>25+60*pg(100,700,l),o=ft(r.tickCount)?r.tickCount:Math.round(i/a(i)),s=nE(n,o,r.tickMinStep),c=r.values?rE(n,r.values,s):sN(n,s);if(!th(c,this.ticks)){this.ticks=c;const l=lN(n,o,r.format);this.publishData([c.map(u=>({value:u,label:l(u)}))])}}}class Iz extends Xm{constructor(t,n){super(n,t.channel)}async load(){this.publishData([this.genome.chromosomes])}}function Xa(e,t){return!t||/^(data:|([A-Za-z]+:)?\/\/)/.test(e)||e.startsWith("/")?e:(t.endsWith("/")||(t+="/"),t+e)}function bs(e,t,n=!0){let r,i=o=>{};return function(...s){return new Promise((c,l)=>{const u=()=>{clearTimeout(r),i=f=>{},c(e(...s))};n&&i("debounced"),clearTimeout(r),i=l,r=window.setTimeout(u,t)})}}class Nl extends Xm{constructor(){super(...arguments);Z(this,hc,new AbortController);Z(this,ff,[0,0]);zn(this,"params")}setupDebouncing(n){n.debounce>0&&(n.debounceMode=="domain"?this.onDomainChanged=bs(this.onDomainChanged.bind(this),n.debounce,!1):n.debounceMode=="window"&&(this.loadInterval=bs(this.loadInterval.bind(this),n.debounce,!1)))}async onDomainChanged(n){var a;const r=((a=this.params)==null?void 0:a.windowSize)??-1;if(n[1]-n[0]>r)return;const i=this.quantizeInterval(n,r);this.checkAndUpdateLastInterval(i)&&(await this.initializedPromise,this.loadInterval(i))}async loadInterval(n){}async discretizeAndLoad(n,r){F(this,hc).abort(),this.setLoadingStatus(!0),le(this,hc,new AbortController);const i=F(this,hc).signal,a=this.genome.continuousToDiscreteChromosomeIntervals(n);try{const o=await Promise.all(a.map(async s=>r(s,i)));if(!i.aborted)return this.setLoadingStatus(!1),o}catch(o){if(!i.aborted)throw this.setLoadingStatus(!1),o}}quantizeInterval(n,r){return[Math.max(Math.floor(n[0]/r-1)*r,0),Math.min(Math.ceil(n[1]/r+1)*r,this.genome.totalSize)]}checkAndUpdateLastInterval(n){return th(F(this,ff),n)?!1:(le(this,ff,n),!0)}}hc=new WeakMap,ff=new WeakMap;class Rz extends Nl{constructor(t,n){const r={channel:"x",windowSize:7e3,debounce:200,debounceMode:"window",...t};if(super(n,r.channel),this.params=r,!this.params.url)throw new Error("No URL provided for IndexedFastaSource");this.setupDebouncing(this.params),this.initializedPromise=new Promise(i=>{Promise.all([Promise.resolve().then(()=>d6),Promise.resolve().then(()=>$Y),Promise.resolve().then(()=>hu)]).then(([{Buffer:a},{IndexedFasta:o},{RemoteFile:s}])=>{typeof window<"u"&&(window.Buffer??(window.Buffer=a));const c=l=>new s(Xa(l,this.view.getBaseUrl()));this.fasta=new o({fasta:c(this.params.url),fai:c(this.params.indexUrl??this.params.url+".fai")}),i()})})}async loadInterval(t){const n=await this.discretizeAndLoad(t,async(r,i)=>this.fasta.getSequence(r.chrom,r.startPos,r.endPos,{signal:i}).then(a=>({chrom:r.chrom,start:r.startPos,sequence:a})));n&&this.publishData([n])}}class Dz extends Nl{constructor(n,r){const i={pixelsPerBin:2,channel:"x",debounce:200,debounceMode:"window",...n};super(r,i.channel);Z(this,dc,[]);Z(this,pc,void 0);if(this.params=i,!this.params.url)throw new Error("No URL provided for BigWigSource");this.setupDebouncing(this.params),this.initializedPromise=new Promise(a=>{Promise.all([Promise.resolve().then(()=>fk),Promise.resolve().then(()=>hu)]).then(([{BigWig:o},{RemoteFile:s}])=>{le(this,pc,new o({filehandle:new s(Xa(this.params.url,this.view.getBaseUrl()))})),F(this,pc).getHeader().then(c=>{le(this,dc,c.zoomLevels.map(l=>l.reductionLevel).reverse()),F(this,dc).push(1),a()})})})}async onDomainChanged(n){await this.initializedPromise;const r=this.getAxisLength()||700,i=Bz(n,r,F(this,dc)),a=Math.max(i*r,5e3),o=this.quantizeInterval(n,a);this.checkAndUpdateLastInterval(o)&&this.loadInterval(o,i)}async loadInterval(n,r){const i=.5/r/this.params.pixelsPerBin,a=await this.discretizeAndLoad(n,(o,s)=>F(this,pc).getFeatures(o.chrom,o.startPos,o.endPos,{scale:i,signal:s}).then(c=>c.map(l=>({chrom:o.chrom,start:l.start,end:l.end,score:l.score}))));a&&this.publishData(a)}}dc=new WeakMap,pc=new WeakMap;function Bz(e,t,n){const r=(e[1]-e[0])/t;return n.find(i=>i<r)??n.at(-1)}class Fz extends Nl{constructor(n,r){const i={channel:"x",windowSize:1e6,debounce:200,debounceMode:"window",...n};super(r,i.channel);zn(this,"parser");zn(this,"bbi");zn(this,"parseLine");if(this.params=i,!this.params.url)throw new Error("No URL provided for BigBedSource");this.setupDebouncing(this.params),this.initializedPromise=new Promise(a=>{Promise.all([Promise.resolve().then(()=>OK),Promise.resolve().then(()=>fk),Promise.resolve().then(()=>hu)]).then(([o,{BigBed:s},{RemoteFile:c}])=>{const l=o.default;this.bbi=new s({filehandle:new c(Xa(this.params.url,this.view.getBaseUrl()))}),this.bbi.getHeader().then(async u=>{this.parser=new l({autoSql:u.autoSql});try{const f=Pz(this.parser);this.parseLine=(h,d)=>f(h,d.start,d.end,d.rest)}catch{this.parseLine=(h,d)=>this.parser.parseLine(`${h} ${d.start} ${d.end} ${d.rest}`)}a()})})})}async loadInterval(n){const r=await this.discretizeAndLoad(n,async(i,a)=>this.bbi.getFeatures(i.chrom,i.startPos,i.endPos,{signal:a}).then(o=>o.map(s=>this.parseLine(i.chrom,s))));r&&this.publishData(r)}}function Pz(e){const t=e.autoSql.fields.filter(w=>w.type).slice(3);let n=0,r="",i=0,a={};const o=" ",s=o.charCodeAt(0),c="0".charCodeAt(0),l="-".charCodeAt(0);function u(){let w=r.indexOf(o,n);w<0&&(w=i);const A=r.substring(n,w);return n=w+1,A}function f(){let w=0,A=r.charCodeAt(n),x=1;A===l&&(x=-1,n++,A=r.charCodeAt(n));do{if(A===s){n++;break}w=w*10+A-c,A=r.charCodeAt(++n)}while(n<i);return w*x}const h=t.map(w=>`${JSON.stringify(w.name)}: ${w.isNumeric?"0":"emptyString"}`),d=new Function(`
|
|
1699
1699
|
const emptyString = "";
|
|
1700
1700
|
return function makeTemplate(chrom, chromStart, chromEnd) {
|
|
1701
1701
|
return {
|
|
1702
1702
|
chrom,
|
|
1703
1703
|
chromStart,
|
|
1704
1704
|
chromEnd,
|
|
1705
|
-
${
|
|
1705
|
+
${h.join(`,
|
|
1706
1706
|
`)}
|
|
1707
1707
|
}
|
|
1708
|
-
};`)()
|
|
1709
|
-
|
|
1710
|
-
`)
|
|
1711
|
-
Reason: ${s.message}`)}));if(n.isViewSpec(a))return a.baseUrl=(o=i.match(/^[^?#]*\//))==null?void 0:o[0],a;throw new Error(`The imported spec "${i}" is not a view spec: ${JSON.stringify(e)}`)}function ME(e){const t=[];return e.visit(n=>{t.push(n)}),new Set([...eR(t,n=>n.length,n=>n.name)].filter(([n,r])=>r==1&&n!==void 0).map(([n,r])=>n))}const iU=e=>!/^(layer|concat)\d+$/.test(e);function aU(e){const t=e.getSize().addPadding(e.getOverhang()),n=r=>r.grow>0?void 0:r.px;return{width:n(t.width),height:n(t.height)}}function Vr(e){return()=>e}const ar=class ar{static create(t,n,r,i){return new ar(Vr(t),Vr(n),Vr(r),Vr(i))}_offset(t,n){const r=this["_"+t];if(n===0)return r;switch(typeof n){case"number":return()=>r()+n;case"function":return()=>r()+n();default:throw new Error("Not a number of function")}}_passThrough(t){return this._offset(t,0)}constructor(t,n,r,i){this._x=t,this._y=n,this._width=r,this._height=i}get x(){return this._x()}get y(){return this._y()}get width(){return this._width()}get height(){return this._height()}get x2(){return this._x()+this._width()}get y2(){return this._y()+this._height()}equals(t){return t?this===t||this.x===t.x&&this.y===t.y&&this.width===t.width&&this.height===t.height:!1}modify(t){if(!Object.keys(t).length)return this;const n=r=>{const i=t[r];return typeof i=="number"?Vr(i):typeof i=="function"?i:this._passThrough(r)};return new ar(n("x"),n("y"),n("width"),n("height"))}translate(t,n){return t===0&&n===0?this:new ar(this._offset("x",t),this._offset("y",n),this._passThrough("width"),this._passThrough("height"))}translateBy(t){return this.translate(t.x,t.y)}expand(t,n=1){return t.left==0&&t.top==0&&t.right==0&&t.bottom==0?this:new ar(t.left?this._offset("x",-t.left*n):this._passThrough("x"),t.top?this._offset("y",-t.top*n):this._passThrough("y"),t.width?this._offset("width",t.width*n):this._passThrough("width"),t.height?this._offset("height",t.height*n):this._passThrough("height"))}shrink(t){return this.expand(t,-1)}intersect(t){return this===t||t==null?this:new ar(()=>Math.max(this.x,t.x),()=>Math.max(this.y,t.y),()=>Math.min(this.x2,t.x2)-Math.max(this.x,t.x),()=>Math.min(this.y2,t.y2)-Math.max(this.y,t.y))}union(t){return this===t||t==null?this:new ar(()=>Math.min(this.x,t.x),()=>Math.min(this.y,t.y),()=>Math.max(this.x2,t.x2)-Math.min(this.x,t.x),()=>Math.max(this.y2,t.y2)-Math.min(this.y,t.y))}isDefined(){return this.width>=0&&this.height>=0}flatten(){return new ar(Vr(this.x),Vr(this.y),Vr(this.width),Vr(this.height))}containsPoint(t,n){return t>=this.x&&t<this.x2&&n>=this.y&&n<this.y2}normalizePoint(t,n){return{x:(t-this.x)/this.width,y:(n-this.y)/this.height}}toString(){return`Rectangle: x: ${this.x}, y: ${this.y}, width: ${this.width}, height: ${this.height}`}toRoundedString(){return`Rectangle: x: ${Math.round(this.x)}, y: ${Math.round(this.y)}, width: ${Math.round(this.width)}, height: ${Math.round(this.height)}`}};zn(ar,"ZERO",ar.create(0,0,0,0));let Zn=ar;class OE{constructor(t){this.globalOptions=t}pushView(t,n){}popView(t){}renderMark(t,n){}}class LE extends OE{constructor(t,n){super(t),this.webGLHelper=n,this.buffer=[],this.coords=void 0,this.views=new Set}pushView(t,n){this.views.add(t),this.coords=n}renderMark(t,n){if(this.globalOptions.picking&&!t.isPickingParticipant())return;const r=t.render(n);r&&this.buffer.push({mark:t,callback:r,coords:this.coords,clipRect:n.clipRect})}render(){if(this.batch||this._buildBatch(),this.batch.length==0)return;const t=this.webGLHelper.gl,n=this.globalOptions.picking;t.bindFramebuffer(t.FRAMEBUFFER,n?this.webGLHelper._pickingBufferInfo.framebuffer:null),this.webGLHelper.clearAll();for(const r of this.views)r.onBeforeRender();for(const r of this.batch)r();n&&t.bindFramebuffer(t.FRAMEBUFFER,null)}_buildBatch(){this.batch=[];let t=!0,n=!0;const r=o=>()=>{t&&o()},i=o=>()=>{t&&n&&o()},a=Rc(this.buffer.reverse(),o=>o.mark);for(const[o,s]of[...a.entries()].reverse()){if(!o.isReady())continue;this.batch.push(()=>{t=o.unitView.getEffectiveOpacity()>0}),this.batch.push(...o.prepareRender(this.globalOptions).map(l=>r(l)));let c;for(const l of s){const u=l.coords;u.equals(c)||this.batch.push(r(()=>{n=o.setViewport(u,l.clipRect)})),this.batch.push(i(l.callback)),c=l.coords}}}}class oU extends OE{constructor(...t){super({}),this.contexts=t}pushView(t,n){for(const r of this.contexts)r.pushView(t,n)}popView(t){for(const n of this.contexts)n.popView(t)}renderMark(t,n){for(const r of this.contexts)r.renderMark(t,n)}}class sU{constructor(t,n){this.point=t,this.uiEvent=n,this.stopped=!1,this.target=void 0}stopPropagation(){this.stopped=!0}get type(){return this.uiEvent.type}}class cU{constructor(t,n){this.x=t,this.y=n}equals(t){return t?t===this||t.x===this.x&&t.y===this.y:!1}}const lU=e=>new Promise(t=>setTimeout(t,e));function rd(e){const t=e.requestAnimationFrame||window.requestAnimationFrame,n=e.signal,r=()=>new Promise((i,a)=>{if(n!=null&&n.aborted)return a("aborted");const o=performance.now(),s=o+(e.duration||1e3),c=typeof e.from=="number"?e.from:0,l=typeof e.to=="number"?e.to:1,u=e.easingFunction||(g=>g),f=g=>(g-o)/(s-o),h=g=>g*(l-c)+c,d=g=>Math.max(0,Math.min(1,g)),p=g=>{n!=null&&n.aborted?a("aborted"):(e.onUpdate(h(u(d(f(g))))),g<s?t(p):(e.onUpdate(h(u(1))),i()))};t(p)});return e.delay?n!=null&&n.aborted?Promise.reject("aborted"):lU(e.delay).then(r):r()}class uU{constructor(t){this._renderCallback=t,this._renderRequested=!1,this._warn=!1,this.transitions=[]}requestTransition(t){this.cancelTransition(t),this.transitions.push(t),this.requestRender()}cancelTransition(t){const n=this.transitions.indexOf(t);n>=0&&this.transitions.splice(n,1)}requestRender(){this._renderRequested?this._warn&&console.warn("Render already requested!"):(this._renderRequested=!0,window.requestAnimationFrame(t=>{this._renderRequested=!1;const n=this.transitions;this.transitions=[];let r;for(;r=n.shift();)r(t);this._renderCallback(t)}))}transition(t){return rd({requestAnimationFrame:n=>this.requestTransition(n),...t})}}class fU{constructor(t){this.genomes=new Map,this.baseUrl=t}async initialize(t){const n=new BN(t);return this.genomes.set(n.name,n),Promise.all([...this.genomes.values()].map(r=>r.load(this.baseUrl)))}getGenome(t){if(!this.genomes.size)throw new Error("No genomes have been configured!");if(t){const n=this.genomes.get(t);if(!n)throw new Error(`No genome with the name ${t} has been configured!`);return n}else{if(this.genomes.size>1)throw new Error("Cannot pick a default genome! More than one have been configured!");return this.genomes.values().next().value}}}const hU="data:image/png;base64,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",dU={thin:100,light:300,regular:400,normal:400,medium:500,bold:700,black:900};class pU{constructor(t){this._webGLHelper=t,this.fontRepository="https://raw.githubusercontent.com/etiennepinchon/aframe-fonts/master/fonts/",this._fonts=new gi([],JSON.stringify),this._metadataPromises=new Map,this._fontPromises=new Map,this._promises=[],this._defaultFontEntry={metrics:Om(bE),texture:t?this._createTextureNow(hU):void 0}}async waitUntilReady(){await Promise.all(this._promises)}getFont(t,n="normal",r="regular"){if(Me(r)&&(r=dU[r.toLowerCase()],!r))throw new Error("Unknown font weight: "+r);const i={family:t,style:n,weight:r};let a=this._fonts.get(i);return a||(a={metrics:void 0,texture:void 0},this._fonts.set(i,a),this._promises.push(this._loadFontEntry(a,i))),a}async _loadFontEntry(t,n){try{const r=await this._loadMetadata(n.family),i=mU(r,n),a=this.fontRepository+NE(n.family)+"/"+i.replace(/\.\w+/,""),o=this._createTexture(a+".png"),s=this._loadFont(a+".json");t.texture=await o,t.metrics=await s}catch(r){console.log("Cannot load font. Using default.",r),t.metrics=this._defaultFontEntry.metrics,t.texture=this._defaultFontEntry.texture}}_loadFont(t){let n=this._fontPromises.get(t);return n||(n=fetch(t).then(r=>{if(!r.ok)throw new Error("Could not load font: "+r.status);return r}).then(r=>r.json()).then(r=>Om(r)),this._fontPromises.set(t,n)),n}_loadMetadata(t){const n=NE(t);let r=this._metadataPromises.get(n);return r||(r=fetch(this.fontRepository+n+"/METADATA.pb").then(i=>{if(!i.ok)throw new Error("Could not load font metadata: "+i.status);return i}).then(i=>i.text()).then(i=>gU(i)).catch(i=>{console.warn(i)}),this._metadataPromises.set(n,r)),r}getDefaultFont(){return this._defaultFontEntry}_createTexture(t){const n=this._webGLHelper.gl;return new Promise((r,i)=>{kl(n,{src:t,min:n.LINEAR},(a,o,s)=>{a?i(a):r(o)})})}_createTextureNow(t){const n=this._webGLHelper.gl;let r;const i=new Promise((a,o)=>{r=kl(n,{src:t,min:n.LINEAR},(s,c,l)=>{s?o(s):a(c)})});return this._promises.push(i),r}}function NE(e){return e.toLowerCase().replaceAll(/[^\w]/g,"")}function gU(e){const t=e.split(`
|
|
1712
|
-
`),
|
|
1713
|
-
`))
|
|
1708
|
+
};`)(),p=t.map(w=>{const A=w.type,x=JSON.stringify(w.name);if(["ubyte","int","uint"].includes(A))return`d[${x}] = parseInt();`;if(w.isNumeric)return`d[${x}] = Number(parseString());`;if(["char","string","lstring"].includes(A))return`d[${x}] = parseString();`;throw new Error("Unsupported type: "+A)}),g=Mz(p,50).map((w,A)=>Function("parseInt","parseString",`return function parseFieldChunk${A}(d) {
|
|
1709
|
+
${w.join(`
|
|
1710
|
+
`)}
|
|
1711
|
+
}`)(f,u));function b(w){r=w,i=w.length,n=0}function y(w,A,x,C){b(C),a=d(w,A,x);for(const _ of g)_(a);return a}return y}function Mz(e,t){return Array.from({length:Math.ceil(e.length/t)},(n,r)=>e.slice(r*t,r*t+t))}class Oz extends Nl{constructor(n,r){const i={channel:"x",windowSize:2e4,debounce:200,debounceMode:"domain",...n};super(r,i.channel);Z(this,Mo,void 0);zn(this,"chrPrefixFixer",n=>n);if(this.params=i,!this.params.url)throw new Error("No URL provided for BamSource");this.setupDebouncing(this.params),this.initializedPromise=new Promise(a=>{Promise.all([Promise.resolve().then(()=>nJ),Promise.resolve().then(()=>hu)]).then(([{BamFile:o},{RemoteFile:s}])=>{const c=l=>new s(Xa(l,this.view.getBaseUrl()));le(this,Mo,new o({bamFilehandle:c(this.params.url),baiFilehandle:c(this.params.indexUrl??this.params.url+".bai")})),F(this,Mo).getHeader().then(l=>{var h,d;const u=this.genome.hasChrPrefix(),f=(d=(h=F(this,Mo).indexToChr)==null?void 0:h[0])==null?void 0:d.refName.startsWith("chr");u&&!f?this.chrPrefixFixer=p=>p.replace("chr",""):!u&&f&&(this.chrPrefixFixer=p=>"chr"+p),a()})})})}async loadInterval(n){const r=await this.discretizeAndLoad(n,async(i,a)=>F(this,Mo).getRecordsForRange(this.chrPrefixFixer(i.chrom),i.startPos,i.endPos,{signal:a}).then(o=>o.map(s=>({chrom:i.chrom,start:s.get("start"),end:s.get("end"),name:s.get("name"),MD:s.get("MD"),cigar:s.get("cigar"),mapq:s.get("mq"),strand:s.get("strand")===1?"+":"-"}))));r&&this.publishData(r)}}Mo=new WeakMap;class Lz extends Nl{constructor(n,r){const i={channel:"x",windowSize:3e6,debounce:200,debounceMode:"domain",...n};super(r,i.channel);Z(this,hf,void 0);if(this.params=i,!this.params.url)throw new Error("No URL provided for TabixSource");this.setupDebouncing(this.params),this.initializedPromise=new Promise(a=>{Promise.all([Promise.resolve().then(()=>d6),Promise.resolve().then(()=>hJ),Promise.resolve().then(()=>hu)]).then(([{Buffer:o},{TabixIndexedFile:s},{RemoteFile:c}])=>{typeof window<"u"&&(window.Buffer??(window.Buffer=o));const l=u=>new c(Xa(u,this.view.getBaseUrl()));le(this,hf,new s({filehandle:l(this.params.url),tbiFilehandle:l(this.params.indexUrl??this.params.url+".tbi")})),a()})})}async loadInterval(n){const r=await this.discretizeAndLoad(n,async(i,a)=>{const o=[];return await F(this,hf).getLines(i.chrom,i.startPos,i.endPos,{lineCallback:s=>{o.push(s)},signal:a}),this._parseFeatures(o)});r&&this.publishData(r)}_parseFeatures(n){return[]}}hf=new WeakMap;class Nz extends Lz{constructor(n,r){super(n,r);Z(this,df,void 0);Promise.resolve().then(()=>QJ).then(i=>{le(this,df,i.default)})}_parseFeatures(n){var i;return(i=F(this,df))==null?void 0:i.parseStringSync(n.join(`
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`),{parseSequences:!1})}}df=new WeakMap;function CE(e,t){if(_E(e))return new Ez(e,t);if(Sz(e))return new _z(e,t);if(Cz(e))return new kz(e,t);if(zz(e))return Wz(e.lazy,t);throw new Error("Cannot figure out the data source type: "+JSON.stringify(e))}function zz(e){return"lazy"in e}function Uz(e){return(e==null?void 0:e.type)=="axisTicks"}function $z(e){return(e==null?void 0:e.type)=="axisGenome"}function Hz(e){return(e==null?void 0:e.type)=="indexedFasta"}function Gz(e){return(e==null?void 0:e.type)=="bigwig"}function Vz(e){return(e==null?void 0:e.type)=="bigbed"}function jz(e){return(e==null?void 0:e.type)=="bam"}function qz(e){return(e==null?void 0:e.type)=="gff3"}function Wz(e,t){if(Uz(e))return new Tz(e,t);if($z(e))return new Iz(e,t);if(Hz(e))return new Rz(e,t);if(Gz(e))return new Dz(e,t);if(Vz(e))return new Fz(e,t);if(jz(e))return new Oz(e,t);if(qz(e))return new Nz(e,t);throw new Error("Cannot figure out the data source type: "+JSON.stringify(e))}function Yz(e){const t=Object.keys(e).filter(r=>typeof r=="string"),n=new Function("source","return { "+t.map(r=>JSON.stringify(r)).map(r=>`${r}: source[${r}]`).join(`,
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`)+" };");return n.properties=t,n}class nd extends at{get behavior(){return mr}constructor(){super();const t=n=>{const r=Yz(n);this.handle=i=>this._propagate(r(i)),this.handle(n)};this.handle=t,this.beginBatch=n=>{qA(n)&&(this.handle=t),super.beginBatch(n)}}}function Zz(e){return"name"in e}class kE extends ms{constructor(n,r,i){super();Z(this,pf,void 0);this.provider=i,this.params=n}get identifier(){return this.params.name}updateDynamicData(n){le(this,pf,n),this.loadSynchronously()}loadSynchronously(){const n=F(this,pf)??this.provider(this.params.name)??[];let r=i=>i;if(Array.isArray(n))n.length>0&&(r=EE(n[0]));else throw new Error(`Named data "${this.params.name}" is not an array!`);this.reset(),this.beginBatch({type:"file"});for(const i of n)this._propagate(r(i));this.complete()}async load(){this.loadSynchronously()}}pf=new WeakMap;class TE{constructor(){this._dataSourcesByHost=new Map,this._collectorsByHost=new Map,this._observers=new Map}get dataSources(){return[...new Set(this._dataSourcesByHost.values()).values()]}get collectors(){return[...this._collectorsByHost.values()]}addObserver(t,n){let r=this._observers.get(n);r||(r=[],this._observers.set(n,r)),r.push(t)}_relayObserverCallback(t,n){const r=this._observers.get(n);if(r)for(const i of r)i(t)}addDataSource(t,n){this._dataSourcesByHost.set(n,t)}findDataSourceByKey(t){return this._dataSourcesByHost.get(t)}findNamedDataSource(t){let n,r=[];for(const[i,a]of this._dataSourcesByHost.entries())if(a instanceof kE&&t==a.identifier){if(n&&n!==a)throw new Error(`Found multiple instances of named data: ${t}. Data flow optimization is broken (it's a bug).`);n=a,r.push(i)}if(n)return{dataSource:n,hosts:r}}addCollector(t,n){this._collectorsByHost.set(n,t),t.observers.push(r=>this._relayObserverCallback(r,n))}findCollectorByKey(t){return this._collectorsByHost.get(t)}initialize(){for(const t of this.dataSources)t.visit(n=>n.initialize())}}function IE(e,t){const n=new Map,r=[];for(const i of e)n.set(i,{ref:i,children:[]});for(const i of n.values()){const a=n.get(t(i.ref));a?a.children.push(i):r.push(i)}return r}function RE(e,t,n){var i,a;const r=(i=t.preOrder)==null?void 0:i.call(t,e);if(r)return r;for(const o of n(e)){const s=RE(o,t,n);if(s==="stop")return s}return(a=t.postOrder)==null?void 0:a.call(t,e)}function DE(e,t){return RE(e,t,n=>n.children)}function BE(e,t){const n=[];let r;const i=t??new TE,a=[];function o(f,h=()=>{}){if(!r)throw h()||new Error("Cannot append data flow node, no parent exist!");return r.addChild(f),r=f,f}function s(f,h){return o(f,()=>new Error(`Cannot append a transform because no (inherited) data are available! ${h?JSON.stringify(h):""}`))}function c(f,h){for(const d of f){let p;try{p=vz(d,h)}catch(g){throw console.warn(g),new Error(`Cannot initialize "${d.type}" transform: ${g}`)}p.behavior&Li&&s(new nd),s(p)}}const l=f=>{if(n.push(r),f.spec.data){const h=Zz(f.spec.data)?new kE(f.spec.data,f,f.context.getNamedDataFromProvider):CE(f.spec.data,f);r=h,i.addDataSource(h,f)}if(f.spec.transform&&c(f.spec.transform,f),f instanceof mt){if(!r)throw new Error(`A unit view (${f.getPathString()}) has no (inherited) data source`);const h=Qz(f);if(h){a.push(h.rewrite);for(const p of h.transforms)s(p)}f.mark.isPickingParticipant()&&(s(new nd),s(new wE({type:"identifier"})));const d=new Ol({type:"collect",groupby:f.getFacetFields(),sort:Xz(f,h==null?void 0:h.rewrittenEncoding)});o(d),i.addCollector(d,f)}},u=IE(e.getDescendants(),f=>f.dataParent);for(const f of u)DE(f,{preOrder:h=>l(h.ref),postOrder:()=>{r=n.pop()}});return a.forEach(f=>f()),i}function Qz(e){var a;const t=[],n={},r=[];for(const[o,s]of Object.entries(e.getEncoding())){const c=o;wl(c)&&f3(s)&&r.push({channel:c,chromPosDef:s})}const i=Rc(r,o=>$a(o.channel),o=>o.chromPosDef.chrom);for(const[o,s]of i.entries())for(const[c,l]of s.entries()){const u=[],f=[],h=[];for(const{channel:d,chromPosDef:p}of l){const g=w=>w.replace(/[^A-Za-z0-9_]/g,""),b=["_linearized_",g(p.chrom),"_",g(p.pos)].join(""),y={...((a=e.spec.encoding)==null?void 0:a[d])??e.getEncoding()[d]??{},field:b};delete y.chrom,delete y.pos,!y.type&&p.type&&(y.type=p.type),n[d]=y,u.push(p.pos),h.push(p.offset??0),f.push(b)}t.push(new nd),t.push(new mE({type:"linearizeGenomicCoordinate",channel:o,chrom:c,pos:u,offset:h,as:f},e))}return t.length?{transforms:t,rewrittenEncoding:n,rewrite:()=>{e.spec.encoding={...e.spec.encoding,...n},NA(e.mark,"encoding")}}:void 0}function Xz(e,t){var r;const n={...e.getEncoding(),...t}.x;if(rn(n)&&(r=e.getScaleResolution("x"))!=null&&r.isZoomable()){if(Ur(n))return"buildIndex"in n&&n.buildIndex?{field:n.field}:null;if(!vl(n)){if(kh(n))throw new Error("A zoomable x channel must be mapped to a field.")}}}function Kz(e,...t){let n=e;for(const a of t)n.addChild(a),n=a;let r;n instanceof Ol?r=n:(r=new Ol,n.addChild(r));let i;return e instanceof ms?i=async()=>(await e.load(),r.getData()):i=async()=>{throw new Error("The root node is not derived from DataSource!")},{dataSource:e,collector:r,loadAndCollect:i}}function FE(e,t=void 0){if(e.parent!==t)return!1;for(const n of e.children)if(!FE(n,e))return!1;return!0}function Km(e,t=!1){if(e.behavior&zm&&(t=!0),e instanceof nd)if(t)t=!1;else{const n=e.children[0];e.excise(),n&&Km(n,t);return}e.behavior&mr&&(t=!1);for(let n=0,r=e.children.length;n<r;n++)Km(e.children[n],t||r>1)}function Jz(e){const t=[...e._dataSourcesByHost.entries()],n=new Map;for(const r of t){const i=r[1];i.identifier&&!n.has(i.identifier)&&n.set(i.identifier,i)}e._dataSourcesByHost.clear();for(let[r,i]of t){const a=n.get(i.identifier);a&&(a.adoptChildrenOf(i),i=a),e.addDataSource(i,r)}}function eU(e){if(Km(e),!FE(e))throw new Error("Encountered a bug! There's a problem in the data flow structure.")}function tU(e){for(const t of e.dataSources)eU(t);Jz(e)}function PE(e){const t=new Set;e.visit(n=>{for(const r of Object.values(n.resolutions.scale)){const i=r.name;if(i&&t.has(i))throw new Error(`The same scale name "${i}" occurs in multiple scale resolutions!`);t.add(i)}})}function nU(e){for(const t of ns){const n=e.getScaleResolution(t);n&&!n.name&&n.isZoomable()&&(n.name=`${t}_at_root`)}}function rU(e){const t=[];return e.visit(n=>{if(n instanceof mt){const r=n.getEncoding();for(const[i,a]of Object.entries(r))Ur(a)&&"type"in a&&t.push({view:n,channel:i,field:a.field,type:a.type});return KA}}),t}async function iU(e,t,n){var o;if(!e.import.url)throw new Error("Cannot import, not an import spec: "+JSON.stringify(e));const r=Zc({baseURL:t}),i=e.import.url,a=JSON.parse(await r.load(i).catch(s=>{throw new Error(`Could not load imported view spec: ${i}
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Reason: ${s.message}`)}));if(n.isViewSpec(a))return a.baseUrl=(o=i.match(/^[^?#]*\//))==null?void 0:o[0],a;throw new Error(`The imported spec "${i}" is not a view spec: ${JSON.stringify(e)}`)}function ME(e){const t=[];return e.visit(n=>{t.push(n)}),new Set([...eR(t,n=>n.length,n=>n.name)].filter(([n,r])=>r==1&&n!==void 0).map(([n,r])=>n))}const aU=e=>!/^(layer|concat)\d+$/.test(e);function oU(e){const t=e.getSize().addPadding(e.getOverhang()),n=r=>r.grow>0?void 0:r.px;return{width:n(t.width),height:n(t.height)}}function Vr(e){return()=>e}const ar=class ar{static create(t,n,r,i){return new ar(Vr(t),Vr(n),Vr(r),Vr(i))}_offset(t,n){const r=this["_"+t];if(n===0)return r;switch(typeof n){case"number":return()=>r()+n;case"function":return()=>r()+n();default:throw new Error("Not a number of function")}}_passThrough(t){return this._offset(t,0)}constructor(t,n,r,i){this._x=t,this._y=n,this._width=r,this._height=i}get x(){return this._x()}get y(){return this._y()}get width(){return this._width()}get height(){return this._height()}get x2(){return this._x()+this._width()}get y2(){return this._y()+this._height()}equals(t){return t?this===t||this.x===t.x&&this.y===t.y&&this.width===t.width&&this.height===t.height:!1}modify(t){if(!Object.keys(t).length)return this;const n=r=>{const i=t[r];return typeof i=="number"?Vr(i):typeof i=="function"?i:this._passThrough(r)};return new ar(n("x"),n("y"),n("width"),n("height"))}translate(t,n){return t===0&&n===0?this:new ar(this._offset("x",t),this._offset("y",n),this._passThrough("width"),this._passThrough("height"))}translateBy(t){return this.translate(t.x,t.y)}expand(t,n=1){return t.left==0&&t.top==0&&t.right==0&&t.bottom==0?this:new ar(t.left?this._offset("x",-t.left*n):this._passThrough("x"),t.top?this._offset("y",-t.top*n):this._passThrough("y"),t.width?this._offset("width",t.width*n):this._passThrough("width"),t.height?this._offset("height",t.height*n):this._passThrough("height"))}shrink(t){return this.expand(t,-1)}intersect(t){return this===t||t==null?this:new ar(()=>Math.max(this.x,t.x),()=>Math.max(this.y,t.y),()=>Math.min(this.x2,t.x2)-Math.max(this.x,t.x),()=>Math.min(this.y2,t.y2)-Math.max(this.y,t.y))}union(t){return this===t||t==null?this:new ar(()=>Math.min(this.x,t.x),()=>Math.min(this.y,t.y),()=>Math.max(this.x2,t.x2)-Math.min(this.x,t.x),()=>Math.max(this.y2,t.y2)-Math.min(this.y,t.y))}isDefined(){return this.width>=0&&this.height>=0}flatten(){return new ar(Vr(this.x),Vr(this.y),Vr(this.width),Vr(this.height))}containsPoint(t,n){return t>=this.x&&t<this.x2&&n>=this.y&&n<this.y2}normalizePoint(t,n){return{x:(t-this.x)/this.width,y:(n-this.y)/this.height}}toString(){return`Rectangle: x: ${this.x}, y: ${this.y}, width: ${this.width}, height: ${this.height}`}toRoundedString(){return`Rectangle: x: ${Math.round(this.x)}, y: ${Math.round(this.y)}, width: ${Math.round(this.width)}, height: ${Math.round(this.height)}`}};zn(ar,"ZERO",ar.create(0,0,0,0));let Zn=ar;class OE{constructor(t){this.globalOptions=t}pushView(t,n){}popView(t){}renderMark(t,n){}}class LE extends OE{constructor(t,n){super(t),this.webGLHelper=n,this.buffer=[],this.coords=void 0,this.views=new Set}pushView(t,n){this.views.add(t),this.coords=n}renderMark(t,n){if(this.globalOptions.picking&&!t.isPickingParticipant())return;const r=t.render(n);r&&this.buffer.push({mark:t,callback:r,coords:this.coords,clipRect:n.clipRect})}render(){if(this.batch||this._buildBatch(),this.batch.length==0)return;const t=this.webGLHelper.gl,n=this.globalOptions.picking;t.bindFramebuffer(t.FRAMEBUFFER,n?this.webGLHelper._pickingBufferInfo.framebuffer:null),this.webGLHelper.clearAll();for(const r of this.views)r.onBeforeRender();for(const r of this.batch)r();n&&t.bindFramebuffer(t.FRAMEBUFFER,null)}_buildBatch(){this.batch=[];let t=!0,n=!0;const r=o=>()=>{t&&o()},i=o=>()=>{t&&n&&o()},a=Rc(this.buffer.reverse(),o=>o.mark);for(const[o,s]of[...a.entries()].reverse()){if(!o.isReady())continue;this.batch.push(()=>{t=o.unitView.getEffectiveOpacity()>0}),this.batch.push(...o.prepareRender(this.globalOptions).map(l=>r(l)));let c;for(const l of s){const u=l.coords;u.equals(c)||this.batch.push(r(()=>{n=o.setViewport(u,l.clipRect)})),this.batch.push(i(l.callback)),c=l.coords}}}}class sU extends OE{constructor(...t){super({}),this.contexts=t}pushView(t,n){for(const r of this.contexts)r.pushView(t,n)}popView(t){for(const n of this.contexts)n.popView(t)}renderMark(t,n){for(const r of this.contexts)r.renderMark(t,n)}}class cU{constructor(t,n){this.point=t,this.uiEvent=n,this.stopped=!1,this.target=void 0}stopPropagation(){this.stopped=!0}get type(){return this.uiEvent.type}}class lU{constructor(t,n){this.x=t,this.y=n}equals(t){return t?t===this||t.x===this.x&&t.y===this.y:!1}}const uU=e=>new Promise(t=>setTimeout(t,e));function rd(e){const t=e.requestAnimationFrame||window.requestAnimationFrame,n=e.signal,r=()=>new Promise((i,a)=>{if(n!=null&&n.aborted)return a("aborted");const o=performance.now(),s=o+(e.duration||1e3),c=typeof e.from=="number"?e.from:0,l=typeof e.to=="number"?e.to:1,u=e.easingFunction||(g=>g),f=g=>(g-o)/(s-o),h=g=>g*(l-c)+c,d=g=>Math.max(0,Math.min(1,g)),p=g=>{n!=null&&n.aborted?a("aborted"):(e.onUpdate(h(u(d(f(g))))),g<s?t(p):(e.onUpdate(h(u(1))),i()))};t(p)});return e.delay?n!=null&&n.aborted?Promise.reject("aborted"):uU(e.delay).then(r):r()}class fU{constructor(t){this._renderCallback=t,this._renderRequested=!1,this._warn=!1,this.transitions=[]}requestTransition(t){this.cancelTransition(t),this.transitions.push(t),this.requestRender()}cancelTransition(t){const n=this.transitions.indexOf(t);n>=0&&this.transitions.splice(n,1)}requestRender(){this._renderRequested?this._warn&&console.warn("Render already requested!"):(this._renderRequested=!0,window.requestAnimationFrame(t=>{this._renderRequested=!1;const n=this.transitions;this.transitions=[];let r;for(;r=n.shift();)r(t);this._renderCallback(t)}))}transition(t){return rd({requestAnimationFrame:n=>this.requestTransition(n),...t})}}class hU{constructor(t){this.genomes=new Map,this.baseUrl=t}async initialize(t){const n=new BN(t);return this.genomes.set(n.name,n),Promise.all([...this.genomes.values()].map(r=>r.load(this.baseUrl)))}getGenome(t){if(!this.genomes.size)throw new Error("No genomes have been configured!");if(t){const n=this.genomes.get(t);if(!n)throw new Error(`No genome with the name ${t} has been configured!`);return n}else{if(this.genomes.size>1)throw new Error("Cannot pick a default genome! More than one have been configured!");return this.genomes.values().next().value}}}const dU="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAgAAAAIACAIAAAB7GkOtAAEFzklEQVR4AezcRXjr2BnG8b8SQ+gJOiA5d1NmZuZVuU133Zf3++6XxW27Ku7LzIzDrMgByxQGaxwfWVFGMly088z7e76Zi5bu6nvP+Y4sKwgC2n4KP4QfgEcvAVdZGHfuM++Fj8HHwUZERO6aMTocsMGhl4C7bbrzr7C5N0REFAC30nct7qwhdH8REQXAfKf7FrjTLPpJ7EPuMhERycB36XD+hX0/DuzSlsnw3OfyilcwAA/vn/yzQQMoUHg9r59hhn7Oz/njH9ncJAiAXNj9P2qTxdhARETufgDYNs4fsH/Cv2jL53nzm1lcZH2dngKCP/Gnn/LTEiXg+Tw/Q+btvJ1+/vlPfvYz/v1vEwA26w4fs8lm4R4GgIiIAmB5GdvGnmbuh9Rq8MIXcuMGpVJ6AFhEXNwneOI//OfnSz8fL49/jI+9lJcecjjJJD15Ho8+yo9/TKUCb7J5vY1tcw+JiOgMILYJcDpNuFQKq5+neMrFbRXLnI+fu7im6KlSCS9fqXDBccLb31siIgqARBOu1SiV8DzKZbpr0nRxWxnQqs8tv51lol/2Xf63qlS6euOpKYZIREQ7ANOHTYdu1SDL/wMOlguFlxW+Hf8dujMX9ryrNx4KEREFgGXd9BQoWu97S0vLbU36T4EOD6NwGf78R0REAZBoxWaJ3qqDA9Kcx3p9YXW1sLLSCoBM5jIV+i7/gwCWl8Nbzs0xLCIiCgDbDiub7b8JMF3exT3kMOM4a3bLmuNczoX22ScpPluK33KIREQUALmc2QS0KjGqT3BxzWKf2VmKhl0sEhD0ngKZS5ZKOgAQERmVAEg05KhVBwFXnXJ62eWLRYoGrRofv8yGHsv/gwOYmwtvtryMiIgMLQCSxwCHh92mQNGg/4gjEwCTxRZMRdOhPfbSl/86/hURGbUAmJ4eaAoULf/N/OeibDsKgPhf0AOgIiLXIQASbTn+la3ICSfRSS+xru84YY2NpU+BqtXwYr4PU1PaAYiIjFoAxNpy9NKGajV5/HvMcTwApqYuf2X+govboJG+/I82GiIiMiIBsLAQdualpStfCIg/AJqc/9DWewqUfABUy38RkREKgPjpbKJtc8xxdAIc7/dXAyBlCnR8HIuSbFYHACIioxgA6e+EODqKr+tPOU0GQHwKtMmm2SvUqcdzpNmM3SCXQ0RERicAVlbCFj07C81m/CjYrP1T5z/pUyArnALFJ0k6/hURGdEASL4XyNQRR2b5n5z/9JsCRdfQA6AiIqMdAClTIM+Ljn/POEsGQHIK5BF+ZGurZpb/+/uxS09PIyIiIxgApiYnYX/fjIDcrc7x79xc6vyn27NArY/qBXAiItcjAMbGnrkJOLzo4rH3/6yvR8v/vlMgz3tKb4AQEbkWAZBo1Ftb3vb25s6mi3vOeXyRn2S+5GuqRMk9cLd2Wp9u7O5CoRBedH4eEREZzQCIdgCZDJTLZd/f8Xe2m9u95z/JKdB2dXunsuP7uzr+FRG5HgGQz8fadbPpV6t+zW9VvLv3DQDLotwol+vlet2/HvMfEREFQLxdW1Cp16v1amWx0jMArOitotHf8hu+v+c3Gj5zc+HllpcREZFRDoD4AzvVWq1Sq1zOf9bW6CkKgPLr/Uqj0njkA/HLiYjIsGQYwMxMuAlYW+Oz//8/X/4/L3lJcvlvQdBrChR896vf1QHAdSIi2gEkm/Yg85/kFOjC5KQOAERERkEGPjT4McC6w/rfYQ6KS93nPx9K3QS8ulVPgdMJE8tCRESGGgAbDGBhAcdhw4YlWIUiqcv/b8Gn2UgNgI0iWGB3MkBERIYdAJ9iMO8Je3e7iu1Klbjg9HS7+5syV3AsRERk2AGQZzB52/TudhVhjVSpF8ybT0X5kUNERIZrjMGtJpb/gyuaCiPk+hARUQAYzq0GwMzVEZCIiAybFQQBIiLyrN4BiIiIAqAK34T3wxp8CX7N0+zZAQYCQRzF4bfMAQroCKETRMfYvWRHqFt0kI4wkaaQDQQ7+33mDPPz9wBwAQAgAAAIAAALU3KeWwEu+dglp7yNATqEADT35Np+/zGNAHQOEIDWgFsyBQAbAAACAIAAACAAAAgAAAIAgAAAIAAACAAAAgCAAAAgAAAIAAACAIAAACAAAAgAAAIAgAAAIAAAAgCAAAAgAAAIAAACAIAAACAAAAgAAH8iAAAIAAACAIAAACAAAAgAAAIAgAAAULLPD9v0CYCSKXOO6RYAJaPff40ASg75tnm+5QLACAyAAAAgAAAMtdasBAAuAADKkJcHO3eZ3Uh2wFH8GtRkZmb2kXrCWUNWHGbmxAwyW2RmtpXSyOrwfJ9X93f+ghW8K6xZSP3LRvgvf4bvw/fgl7wq8iUlSaqlYgn2P62SgWYqcjBXWSAkyQBUXMCv/ysDST73d5j7/P6csEiSAajYgcy/LzWX7Z3rZQ5WkCSFGICKJ/jrp/cBh4f7f/9xam4q9ffUe94jSQo2ABWH8BPIzM9n5uYyf9/KHGe+zbd76UWSFG4AKtLp1YWF/dLOjjiqp94AxIAkA/D8zNISi4vXCwtn1L/hTTTCJ0n+EWx1lZWVaIn9wgwz0aaYInCSZACKRdbXWVtjdXWSySmmppnuppvASZIB2NxkY4N0mkJhnPFok0wSPkkyAFtbpW1ujjASbYyxDjoInCQZgNNTdnfZ2WFvb4ihYYajIUkKPwCZTGn7+3XU9dM/wMAgg4RPkgxAPk8uRzbbQ08vvX30VVNN4CTJANzfc3BAoRCtm+7yCJ8kGYCjo9dBO+0ddHTSSfgkyQCcnXF6yslJE01ttEXzGnDxIMkAXFxwfh6tmeZoLbQgKRZkAK6uymugIVojjUiKBRmA29vSbm4+8KGOumhIkmIRgLu70u7v3/O+PCRJ4Qfg8fF1kCDhJaAlKTYBeH7m5aV0D7XU1lATDUlS+AEoFl9XQhVV0ZAkhR+AqqrSqquBIsUXXqIhSQo/ALW1pdXUAE88lYckKRYBSCR484aqqgceykOSFH4AIu/elXfL7Q030ZAkxSIAHz6UVld3xdU119E9kqRYBKC+noaGaJdcXnARDUlSLALQ1FRac/MZZ6ecnnCCJCkWAWhpobU12jXXxxxHO+ccSVL4AWhvL62jg0TigIPykCSFH4Dqarq6SuvuLlDIkcuSRZIUfgAiPT309tLXlyWbIRPNH4NKUjwC0NdHfz8DA0+Jqj32dtndYQdJUvgB+PCBwUGGhhgZ2WFnm+1oSJLCD0BkZITR0Wh58ptspknbgHiQZAD6+hgfZ2KC4eE06XXW11hDkhR+ACITE0xOMj29xdYqqyuspEkjSbEXgwAMDzMzU9rU1DLLUQCiEiBJCkItX2x2lu3tod3d5P5d63XrW94iKQ5kAJp6elKpVDKTSWbbkr9Nfo2vETxJMgDJ8j5+TGXzyVxyND/KFpKkkAPQD0lIlQPw7l3qs+8k8glylHaHJCnAANR/OvcrTzqAkQQfeQ3AHwiNJBmAmX8596NN8C8+g1xlewRCkgxAz3+98H/Hv6v7lwbk4ZEvNUlSVbFYRJLkH8FiQpL0D/buAqqtNd/7+DcUSQrBQ4TgGg6NNEyZqZ13pvJed3dZet3d71123WXZdR13OX7OSIVOE6BKC6USCMGC9oS2+z6bTUIoFkrP9Ib+P+u3Uk+C/X/7efZOycHEanzwy/Aq643CS/Cn8MPQBQWk6YU/htNg2jTrmDZJDnwV/Cn087TNwz/B14Ips9TBL8I5duwe/AUcA9Nq/o8TQshVQL3gTMaDIQF9azPKWl6IwdhywuxOIJlOstZ0MkIIkT0FkN4BLihhcO3ov8Im/DAGseVEeFK1cDBZAFksnowQQmRVAYxAL7iYck71Hy9Ln/4zbK7C6IBkHrBzFggkUyoFIIQQz+KVwL30O/v7nH19rnf1NTf3wTCbej9JHoi9SSzKGPRgcOI8ylEUE2g8JhxmYABNS9v8cQd4TwvLvp2thMPh4eHhRCJRWVnZ0dFRVVW11bMzzMOn2Lk6OISy7dOKRLhy5cHUVDw/P15XN+PzIYQQWVQAceJfevClvl41/Qf6XAV91dUPLRYyKQDF72fsc3pi00ZpBAlasfrwsYYJuHWLM2d4/XUePgRaqQpwOkAgkMmkPXPmzJtvvnn58uXFxcWampqxsbETJ05UVFRsUwBP0gF1y2H7Ahgf54031DObHh2dtlimOztZWqKri2whhJACGGDgLd46c+dMX99CzO2mtpaurkwLoLiYQIBYjLHPqhooX7TkkefE6cBhx06ahQVCIT3nzjE4VaaP/oMHCQQwm9nO1NSUGv2qA954443p6Wmv15ubm+t2uw8fPszjPsJ68+Rt3QGvwImlJZRaqCNDg4P09vLaa/H+/nh5eXxxEaeTjg727ycrCCGkAAoosGBZYCHW309dHfX1NDRQUUGGmpqW1wFjxGKTX/ximLADhxPnKU6RJhRayeAgvC9AYDk1NWRgZmZmYmLi7t27k5OTwMDAgN/vV02AYbvD9dIt1hYaXISX4FTsP15+qVqrLqGkkEIysbDAzAyjo3FNi09MxCMRxseZnpYCyBpCSAG00OLBM8jgzbmbsStXaGykuZnDh8lcIKAKwMilG5ecOI1FwAEOsOzmzdUCwOslEFhJZgoKCvbv319SUsIytftfVFRksVi2LoBtpr+G7hb0xLjwMhcufFlr76LLi7eRRjJhtVJeTk3N9NTUtM2maoDsIoSQAjBjbqf9Bjeucz129TwtLQwM0N6uT7cMmc3GRpCesbHwzMoiQKWSytnZ1el/v8xJILn5kzGHw9HS0hIMBvPy8hYWFurq6jo7OxsaGmC9byJNof7rdTRWxOP0vKRGv4pjMu8UXUGCKhYsmS59vF4WF+NtbfEy0/TgJIWF2XT4L4SQAlBaaW2hpZnmy4nLUzduoDI4mGkBGGprjY0gldgbb4QJG4uAE5xITf/he7nGWV89Nhs7cejQoZycnKampkQiYbPZVAHU19fzBDRW9fSo0W+6cKHg5t2TnDSmfzXVZKi0lBdfnKiqmpy8MW39UOLf7Nhs+m9mESGEFEAeeU00NdLYQMPUzesMDenx+cjLI2Ppi4C+K31GATivO0OhDqMAjAN/PR4PO1RaWnry5MmpqamlpSX18/z8/N1O/y9/WY1+lhPkPcb076STHamqGqgaHGLobnCUr+uipobsIoSQAlDqqVepo+7i3EVteJjbt7lzh8bGHczVffvw+03GyYBYLDwediaczj5VAI5QiCV3g7H5o6nbJBM7U1ZWxhPTSDGpektOf4/WHiRohB0aNA320nul8sr1/++hrY2mJrKOEEL+N9ASSmqoceOuppq7d/Xcu8d2ND1pnE413zW//77fHyUajoTDw+Fr13rvThfNqd9fDlbrun/+DvskaBhMKtPTqenvmMw3Rn8XXfvZzxZMjydqip7hTE9uT+jg3H2fj85OSkrIOkIIKQBFjX4VFy599I+M6HnwgHW0tKxnXORzMRD4XZ8v3BgOR8PRaPg3Dx4MGZs/DQ1b3OHTVwg/lD7Adcnpr2/9p6a/C9dOn9YII5fyLvUcuT7Y3U1XF14vQgiRjVtAyuoLuJaWiEaNnRycTnZoqCkQahxTsQyM1X506LW8Xw4H/r8jUG4PlDfzDJhYs/W/UgA9PUEOd9Gl8gIvkKKRIVepy9ftm+vOzTl8+ILqgOwlhJACsGK1YVMpoSQ+Po7KxMROC2B+nlCoIhQKhEK/0fhXFY7PePI/E1G/sh+02/PsDhxFFD2b0a8MDaWmvwdPV/K6TwwaO+CiqrvqePfxfd1VOd3dORbLebKWEEIKQKmgQqWc8vjkJFNTKlvOVY11QiEjnqGhoZPek46I93ok4vyhL4S0kB27ylGOZnp/O2dic9PTqenvnDJ3pV/1r5Hyd/DtUMmWmqFbj6PbceyQIweMnCVrCSGkAMooK6VUhfh14nFmZnY0bwcGCIW4eFG/7aCj09tZH/E6IhFGRsKmsAOHscXUQgtfecnpbx6MBJNX/bs0F2neC9/BdrzQnUwnVXAMcpL5EtlJCCEFUEyxFasK8/PMzel59IicHDKgyiIUWknR2xV+/P58f8DrNc4nJyKR0P2VRYADhxUrOxePx43XAeTm5rITxta/8cqvIEf06a8F07f+Tej+H9v1XXdaGjFUru2AL5CFhBBSAIUUGkFZWFhJURHbW53+d+5wAr9f8/vxO+rr8XqJRFTunDsXYqUDjnGMnZidne3p6RkcHEwkElVVVZ2dnW1tbWRoaCg1/TvoCGorV/6wI4Vrp7+DdOXrOuARWUUIIQVgwaJixozy9ttGMimAq1dXC+AABwIE/Ph9+ACjAIyE765uBLXSSsbOnj376quv9vb2Liws1NfXT05OWiyW2tpatjU9TU+PMf2dk2Zj9KuYMe/s9WhzbK0UvlZPdhJCSAHkkptPvooJk7a0hJHtTE6ubv1XPLD78RvBUFi40gEjI0sjnwk9XN0IKqaYDESj0YGBgQsXLrz00kuapjU1NVmt1paWlkwKwBj9Kub/iATPnlw+99vq5DYqm47+JqgkpRshxN4nBaDsY5+KaoKlhw9RefQo882fkYjpNH7j8N+GjZSWFqMA1O3dixfDhI0OOM5xMnD//v25ubmpqSk1/YGRkZGZmRm1FGBbly+nLvwPvv9IF21BbndsNfqVpuUgBfDcEUIKwIRJBUXTkrdbuXRptQACyWP/tPOrST6fUQAqoWjIWAGoZLIRVFRUVFZW5nK5SkpK4vF4c3OzzWZTP89k7cCtW/T1AV3vvxNEBRNbaIQmHvPHPBeEEFIAj3ikoqGRk4PJpOdxx0mKxVZ2fhZDHIdmmo0CYL3S0pWNoGj0wcJCiFl78oRwCSVsqaKioqOjY3x8vLi4eHFx0e12BwKB1tZWtnhmBk3T35q2Jdq4yO2L8EdwfOsCeG4JIaQAHvDACPv2Gdniu26FQkyHOKQSXbmKNEiwjDI21NHB+DgWCw8f3oMw2BmzE3qRF9nO4cOHLRZLe3t7IpGorKz0eDxqEZDRN4Ts1COE2IaQAkiQMIKSn29kszEbDeMN6aEPgxnzNofzx4/j8RjnFUJgB4eeaBt2thNYpmmayWTCsG0BvKBHCLE9IQWwwMIiiyooZvNKHmdHGcUeAiM7kjxyf2h0QDKlZGSL6a/YN/+1EEKIHDY3x5zKPPPk5LB/vx6LhfUewcXk9J/giUUgvJwQz5QQQsgKYIYZI1itKpu+BCyUzGV2Z3UR4IB2nhEhhJACmGRyiikVSkspKdGzoYPL+VUypPGsvG85f48QQmxNtoDGGZ9gYpJJystXIoTY84QUwDjjY4ypLLCAzaanogIhxJ4npABGGBllVIWiIhwOqqqorEQIsecJKYC73L3HvQgRqqtxOnG5EELseUIKYJTR29y+w50YMWpqVPQaEELseUIKYIihW9xSwWajvp66OimAvU8IIQUQJ36Tm4MMqhqgqYmGBr0DhBB7npACuMa161wfYOB+qZnmZhW9BoQQe5uQAhhn/CpXjQ6gvZ22NlpbsVgQQuxtQgpgmGFVAFe4Mu+w0tGBx6PXgBBCiD0nd92vc61Y22lf6rRffeEFvQPMZoQQe56QAvDhS5BwdDjc3v6aAwf6PZ4RhBB7nZACMLyr7F01vhq3113j9dZAH/TDIkKIvU5IAeDD4XU4fI4aOzXghhroh+sIIfYwIQXQBl7wgZd2cCcLwGiCfhhDCLH3CCmAYvAlk4NSBO82pn/aUqAPEggh9hIhBeBLHv67SFe9nJq0JugnuwkhhDBpmoYQQgh5IVgaIYQQUgCmjXIY/gzukrke+C3wg2mzZPK4Rk7BX8Ntnoj6Z38C74Zq+Bn4ArtzAX4FmsCUWerhF+EcG/hx+Ev4LAyzVlR/ezme8WPkwnfDh8lEDP4W3gsm6ITfhStsYhT+Kvk0fPAHG1wcZnraqYDvYnMP4b/gW1P/4ImfzPNg03eWKS1e+H24yjv1kX0P/N7az/8p+Hf4Xih9Sg+RbgD+GI7tfuyY4TvhP2CerX0GfhSsO3zOJ+EfYIrtDcMfwaHN7+o74P1PswA0NpCHkcw1QSN69rE7juQd1bIXzKx+NXwCPZ9Ev30ZvV7FQT3iK8eMkXeEGw5Ap367qgw6wKPfPn31yVif1h0V7uHLQDOXb4TNGIe6Q2s/zKkOGGAXjLtoIOvNw1W4podDxtpEzw0Y0G/1tOnB9RxP/6CejGmIXb6zLO9kAaSmv4U1OvRZwS39llGepjxoSKaXXUjdC89hAWjrVkp5WxWACQrAt9HoblLZTQFYocHoALLY4iLXrnHNz7VkB/wuKUMqRg3oMWog2gZ27DxP6iG4ixWACfGEKwCLyjs5/Vt4XAF0ZFYAuzh230UBOJN34XwuCyC9A85zfphhLV8jj2/Me6wCvj31hefTk/L+1BWljZ+lcQZ3an+juJiuLioq2FyceA89k0ymHf43UNCVesiNvX/TMwBnSeOCI2zo28egiqcskdBHv8rVWq6BUQCzrHdjNUYNfLKNNpVKKslIxu+XGLzOWp3gSXtHvD91CuCt9S8cpzX1gcjU6CiRCBMTzM+ztERODmYzJSU4HNTVkZcHFCdHfxDKSDmzflf7/OrEN9VR58CBMjvL8DDRqPqJ/hC5uRQVYbfrnzlWK7szPj5+7969iYmJ2dnZJXXnUFBQYLVabTab2+0uUW/IU6Ge/L17q++lffvYv5/yclwu3G629b/sfQdYFGnW9SmBJgoNKJIzggKCIKLojDppZ76dmY3On3POOeecc845rRu+71t3djbNrI6ZIAgiUTI0OTTdQHdD/ef1LmUrdFMdGNedPs996oEOVV1vOOfe+4Zqxs6yaoNAFTnPwfIg1FWGh9WFNjZgscQdOhRXWhrH9wLCzAzGxiC/1uN5+muzspCXByBV2F/Z7qgAhrzMgDotG8ziIpxOSGtJTMShQ8jPR0aGmaaeDhR+jMJ5FBija/x6Y6P6hb4xh7lWtK5gxUtDqoEKo7X7JpmPADuCxBtP2/tlX5cYAe5hb1ze8WeIKSAdE9rEXdz9FJ9SAC5b2FrghW8Y7J8niwp2I53iYhT/KorvbgsAa5Ed/rXX4Bud6PwxfjyIQRwQAfglnmWvW8P3LuOLAD7wqwHZu39f3cm/Um+FE5ub29Tfg94F9OYr6l+Cf/Q+jQOc/bjaj/4KVFAGUpEaugD40IBKoMq7LOQru2nACW+Vv2yS1B4+RH8/ezV5VLGzIQCpqYraSkpw7BjNSP6U7PXjh7e57gAOnMGZ9/T3LO0PtUePMDiIqSksL4sA0NVQ5y8rQ02N2uY2KJD0u7q6BgYGRkdHZ2dnKQAbGxuaplEAyPtHjhwpKCg4evRoVVVVIkkqaHiX0uwsVldFAIT4yKfqLqqqeDuB1vPgtgbwZPX1eP99WDqacf8+r6Uuur7OO4nLzIyraow98XVZELo3WInt7WzVSnEpA/y1IgD8tXTs+GtZp5WVVfn5wv5+/BcjCOBRB9SvYn8ZGnrOXRAtJwnwtLwNEsieRVBYiMIOFN7eFoCKCvXzTp+Gb3Sg44f44RjGkMDvR6PwS+osgG8BCF0DXofArwAYrd4E+4dXAACn7lzRVvpi+o7HtHsVu+4ddEcbS8p8CQCtC12/ioUF4L33VIcnF7Bl7wYq8BCGBjDwK/gVd3EBit5X36dnYRLkL82HBvhgfx3hh/C+lwA0YR4msQU8gsQBN1kONEMGkpEctAD40IBKmt+vGBpwQllA4I03N6OjA2RnupxknJWVGDegwZ1ggZDF0aPkkRNzc/VnztTFxNTtqE5fveEeUKqXFtmLlu9cO9zaigcP0NeH8XFtYUEXAbBaVXhByiCV8BXKQGAgHfU3Nzd3dHT09PQMDQ1NT08vLy9vbm7qum6xWKxWa1ZWVnFx8fHjxycnJxsbG7MNgg6xlPhrLRZsbdGHIPGRhlSXobadOcOYMMB6Fg2g36Xn5GDp/t2M69e1O3fQ2cmyYmYyPi4hvvhy/Hg8pgAbVA3n7CGJuHED9+6hq0u1TZstcWXD4rFsRm3akzQ9I4NlTrYtHh+vbmiorq2thj8UAMdEAFZXH7ISqSvd3eq0/G2GEFIARMt57xQGvnjhAjVgbwGgkdR/BUvuRH5eyVVtrSrY3TCPeeY52NG+i++i8Liw/y574/8AvnAA30/GajDs77seTWvA5f0aBHbB5dJdriSXxcJGv3vK1WD/UuwCegZ0CEQGlABQ3mmPH/sSAHk8PT/khlu+pqJ4c/itUKXn0APPB18Mn/svXgzN0ICZeAQON9ClZEAFATSRAWoAlSDxpZiXwBu/fh23bqGlhe5tNrKLUJGBjAQkQIfT4Zx2TA+PDk0ODuZOT9fZ7XVud/3581HP989x+ADfyF7NdnzqcNz8acadO8XD9/PyFtOaVE93uehgeAYH56Za58hQ6v/4eOoNkyABsf/169dv3brV0tLCIIDkTk//0KFD8fHxFACn0zkzM/P48eNHjx6NjY0tLCwwMrhw4QIlIWD2v3ZNlRLpj8THSOWVV+jukHoU+y8vq5iABcjj0pJytC0Wn91hGH6YIzOTxdC30dys8VrXr6csbCYiFUhdX1+P646Lm4qDDZiCshPAKewOXVdaRQH49FP+4DJPUSkaWaexiKUuUh0nlice93cuDg1Vzc5WOzerPalRpwpA+A8C5ueHbt0aunvX2dZGIU+YWGS3z0R9EpKiEOXcck4tTfUs9ayTGFggBAMCaqE/UDVYTmIMeByK/fl1HhlL+aYdagAA45vmmVYLH3/gLeyKVL7zmY0BkKolCnOvrrqI/+qy/OiqxZKIjjS6JGxNBsFmP91NzifI4aIBdBrWhf15rK7e9dmTpH4xJhNZB/wa/cRABwN1UxrgFchcQOjgfXnzPs06tUbKPoqjWcgKzHmXaPrEifXY2I6+voHR74kA8EiTsYF4xOPnFnTfSFu3b5NrWJn1qD+Jk/zNLAf2agCrWJ3EJO+ly9Z16JPoeldaPXIOw4Lz4MEkHLcdzptLjuvX34y/efw9nS2FTkVsLBMbpH02NvIqo4IJUpX40eYFgEl/+v5k/2vXrg0ODp4+ffrkyZNlZWWZmZkJKo9MN3SVXj8jg9bW1rt3766trR04cIBZoLfeeovZoQCGRuhK81dSA1ZW8MYbOHkSpaXMdLNrUADYAdmo+LPVZ27eVPfGvBm5nO8GiA2Fzo3u9uzm5qqFU3nIk4pgwE1/Im4xToWDU9t2yreoM3Rgzd69ywo9h3NVqMpBDpuiB54FLIxilK20d7C32lFa7a4u2CzAJtAIP8iYxfEbg0M3W4ZvfdzS3Hzcc7QK58pQlotcdhkKAJsKeZlXue68bmfskpLCaIC0sNd4gKpwMQZXW6R+mg8B2MSmvE0NYGnL13Y//+V9Zn8fSew0efmzEAC2ue5u+j8Shbnsdhex6YqJuxLznSSyEkufvMwoj7Ge5sX+KfAFCrZoAI2+oAOGBtDf2cH+IsVsTCg+JxFAqHPeNB/vhHHuCBvPs9SfMm4n7wtT8w/x3GEeLLJz59jbmSHh2Ry9vW2UgbEBkQGaIQMWWBB+6CGWC6uZ3Y7My1omU1zAhbM4ewIn8pEfhzgA61gnWXSjm/08ai2q7kYd7wUC0xpAAXDcufPXs2+91aAzwcPiIDdaLCQ7XlY1VZdLJVSWWWCDg6qOFhdVkZoAXf729nb6/mT/hoYGuvZnz56trq7mkG8cfXPA4XCMjIzk5+dTD9g/Hjx4IGPCOTk5dXV1MAlqFJMe5FP2tbfeUpmNs2dVrt9qNWYQqM5IyqMYfPQRi1Qy7EGks1yufper19Xd/frEa6dwqhSlVlh16MtY1qDxXxC92wLwF3yFXeMsWTbIdKSzWl/BK01oYg0CkDpl/+1BTzWq82x5VderFPuLNfleaXgTx24eG7o5NHJvJAUJbCQ1qOGgEDmY414UAP5CthM2G2rVp85PeXWVEBsd3UsAWIqGBpBvxiUI2DX5TMIR4yVQeALynV3xBV+v/SdlAePfmdGYVHntsxCAvj42R0ZhJDJJR7pWVtxs4B6PJf7Kr0lOth06pFEhqaJsB7W1NQ0NNVFRNdib20jjYmQGcfF3FQBJ/tCY9fOd/zEXBPhgMx1hxfi4wftiySOLivFxwVsAVN4jUOTn0ygALG0aq2alt7e5t7d/QrE/zVsG2E/CxvyhY2aGIsWMNr1FzmStRe1pnKYGHMZhbIP9mcXCO6RXAKByvRI3QASkARv/em3sUuWFV/7q2bOv0HXeBsc1lX+ytqa6PPmTHMsEOhszO78ZAWBuh/kfevednZ3M/NTW1jK/f/HixVSv79LZZ+o/OTmZKRQODnOImJpRWFjINFFlZaWpIGBignXKUuJPZKjH3qSmqZw/D29Qzfi6283fxG7Bz1PJ2DEDFwCK4sDG6OBf6c95A+dexatkWJ+rFG/AJ5aW6CCyJA+hjMEcG56wv1GnPC21ZA5zVJf4uXhc3xYAD3Bux4rQSbK/soM3D9a01Gxgg84+2wMFIBOZRlOkDHCof1abZYNnSn+F5Sa1aQJeAqC8NNGAnQJguP9qwpjxHdP4CG9fAb4B2AMhqNcVrf+eD7BjdkcyfLyw3wIgSVuG7a2t5Gm2cSZh3IWF7vj4xNH45ssrhy8vHaqf4lsSHxyZnz+xulpz7twJEwEp1drgcw6nSRBAGSfHeY/DCPurmiiuheR/LJYwerR6GKeOsxU+O9KbNDSr6BjnvKk/xHy9lJoIAI/Ug6Xe3juUgcmnMmAMEePnBOPK21I1CfDX84fRJfRmf2/K4FsQrD9LPa9hT5wBzh7G+WqcOLlLZdNXZkCgOrsw18qKMhNgTp/ePfP7zPUXFRXJJB/F/jvAgIAywDlC/Fh3dzcHivlFfr20tNTMZVQpsRdI0plKz/Hq3cCmRJ3gxdgxlWzYbIYbax4D9q/8OLHh3W+/W/9KPWk6mC6g6zIuzSNzJh541rCGHYhBDLUBgkVANMADdbzk3Ugg7K8q/T7YgDlKRA1gO9nphdC/ydKzOB86TUtbWR6G1KbHo4b6/aKgQJL5KhyclzEAGQr2+iJpR9x/hqQorBb29znR6Ns+JADOYOnk0lMJ+OoLXAdAF6O5mXlGagB5mblIOlFkZ1damivhkeVfnHvNsgLLwoQ+MaANPHr8aGbmxyfsjhpX/Ak9K+18JeLNUhmNzCApIB55iZ2BGAeOTbj/Wz5e8IFNIA9be330gNef/srK4H2h/gHbUdWDG71zPirHGi6QUGjbMkCb7+u7SRmYUuzvPVOIn8MLx/S0TPzXoDF1SzefdQkzEA0wLQBnoeyED8GnM8d0vTgnWF+nDwyXy1wAM2Oz2Tjxn2l9RgBkefK7b4op4Ac49ksB4KgAv8iv7xSAsV1bEUuJhH74MD0t5OQg3Qk4oe24lWQoArNalU+2sMBEFhnQWwDysDeYpqdzzZZJ9g8y26dpqjSTkmgTqxN96LuN29QAnpZxwAFf/WVFNOBZARjdpn4eOyBI1pPhG3SkeAtxehw0sCrFyOMmgwBW4HyLHYYGlJTsdP99DP+anKLzPcCJgHERghcuAHQxjKQtLl1CUxPDUlKw6/CUK7HD8u9+v8Uy8K5ljiXVp/cVaoXdq90112tObJ2oRCUkZo/fuyaMoeDp7SwQryJTPN1wG8O/Qv08+gjYfUwQ/D5g3z0LJMiGfGdM2W56/ZrXOjAfO5LNAz0Y68WHvXikNODUXzloTS/MPHymOK/46CHF+7SDOLgfGRfyvmHrfX3D5eVkqbn5+T+8cLV/QGTAXY7S8he7aNrtJj2RpGhpirfS6dNJ3t+8BpjEnwZ0v3x14IAy8V7FTPx899LSEmf18JiWlkbHPz09nZM+fYe2GfwAPymLBhYXF/nFvRur0wkpJYeD7K/IPe0B8ACaj2xmLC1WuaX8PL9LPfPCn8DeSEbeYeTnoIBMGvyIT2amLEpYu3//Jm4y6c9Z8+RLOu80iv3uSuCA0gCPd3oTyn7dnmkSFXKsremkes2jHdg8oG1pJmrT51CwW1JAXgKwhS1j/g/FXD7qb5nqd+EbVxMD04BLPzcrgdkW6YzTm2R6p7paLZfgeNSZM8yIufAtl+aKOeWKiclJseS8hxMckOEUguM4XugurLlRA4E5DTCmA01P60YQIAJgDP/aYUdx047hX3Na/JE/DTjD7/hlf4FvAXACo4Yld43GPx79+jffsXJuYEZGQVHB0fLC5PJCHDqI/cRGwdG+jbLejb4B9+NJi23u4MJU0p+MH4hPQGY8QEuAsswXuOkFGYo8BXDkg3RjREL7oQFSxWEE53c6ngAAB3iZ60+iz+sbMvmHnyQ4NYhf5BmwA38Sz6Bxfd0oJeXXJ32CPwDcAzQfYekPobC8rMKFzU1aoAIA5AnvhjTqL+vRGLt4PDOdnd/H9xkHMMIzBIB/k0F3yXyuKw0wB413abNRTRUtra6ynLSNDd0jSaQtBAjvrD4ZblQiAAZSQjtC/TwuYxmFtXtn/y/DF74ugvJSbgUh0ej4OEWV96+82Lo6lhwbGtnfBZfFsmWxaDExugaNLn+BXsAxGTp3ye5k3IBpDRBWl7lAWPGaD0rvxhj+lTleyhgU+8PH2A2Wj2AxOqCRXfuHUNzvxOX/9vF/+29YAmCFNy7ADBKAk0ApUFaF0hiU0hX/X9/u+ST9WlpWlsa+QQXt62PpMRskEXrYN5Xg6Xt7edR6e8v7+spHR+3Rs9Vvud6qiFJjABVIKQdywjkcrAUTAdBcLkkHW2ChIVCsA3gxGuB5AtnvIWYb8AvjY6R+fpHgpPgopjF94y4ZXAycHnvg8oOCywUoK4BP/Aco8ENEfHxQA2M/Af6wtI7gNcBqpXfIMlK0mpvL/jo4OjroHGRyRtx/SfeRIupQ93zez7P3Nk7kA5rsBDE7qwTAbldCycXXbverm5uXgiJYbwGAsSDAEADRAJkzFLQAfA0GXkYBYDFTdhmQxsWxIEheEgSR+tmbeVSdWJn0NdCno0HgftZfexO+QZ5/OhLQ3m43pgPZKqzy1wQmUHxe8j9BTJeN3fmqDoxKtNBx9YMx4N2rwLmQRn8P1uNUCRT7M+FO+93zvT3zPb29VzfZvkj9chQZYDHukfzRTJKqUL/3MX4+t0KR/rsyx5RHdr+ft/mgenDkXB3CpK/wIbjH52maUWKm8lOeDzybqN7EMbNlLVQVzKStvDDUNvsmQ5bMTNX2SaNk68nJtampgcnJgZWBFKTQ/WcvZhyvQWN2yOTGfeT6tjaVHGbvGR3lKemUpi5a0u3JybwceanroOVK1P1vRCEIUKoksX/kCKaNuUC1tQvaorj/PBruv1SKT/wSduJtAC+1AIgzQmH3Tq6JAIgGbAuAj7birQFvmh0KZmV7toOA4YpUkWKkpJie/Xl5J/tf9pli71ACQO7/b/HUgNCJzQprIxpLvWSgzN3b09XT23cVO2UgLS0Eh3QX6o+Zy6reJn05eve0F6wBMTE0aStsOeJABLyXYwOAF6MB4stL0l9CAddeQ8fubTAdxC/y6+L+7+EKiQEbX9tgMn0NJUCtmbLWQ9psWzdf23nAmK8pfa+/ruZwk6qZNpiaImGr0ezBweXu7ubF5iUsUdzSkEaPhBN49mT/hQW1Eu7uXTqFaixyNKFCdf+abHqiMvStx8U9ZI1EDyGqH98JKQiYvrtkzAcdLloU9n9m3fAvNKL9d1rGWqo2pqdZo0zFiADQkrwFwLcGmEFqqqEBpLMpsr/z8eOh8bShXBn+PSbuv/o9e+CNPf7XvfcB6gAxKR+KB86FrgEEk2BNaHpGBly9PZ09A5QByQXJUZSAdx4IOPzV0/M8+2uzGce2SZ/2WU37uQ2chUnExzN3zk4ry33pCa5gJaAyxWllLwoJCir1L6u9Vp8AvsFsj5H657IAGQ8wtdKbUTQTKZpm1+wr+gpz0Lum3nSEF5qc1YzCXISq+AH4QFYWjRkhcgU1gGLABkrS4DTC/ul+WSUwjvECFGAvtLbiyf4UuNdu4UoITkFkl6HfTqWhAOgsKGYmLBNQAuBz6Nj8UPD6kxTQFmfsPhEAmvE2L/e5FAA2xJQUcVQp43TOqb2sWlcO1EZAmuuJOtD0sHgjJSWGAKi03+jw8MiofTh3eD3a81Qcwg1t356ykoEMmrcM9Gz09Hb2DvVffRoKUN0uXlQdxjQ+/lgFxQb1b86kG/6+8QeCAt1TmkS6koqmnw6faAfuBBYBWK1UOx4XlxbnMT+DGQccptZDWKCov0HZi0J0dDRn/qQ9wcITcFsI7vTALYB8zRnlB/gxADIdKNWM0rP009QkKQ7qzs3MzWgzNt3GiY0MCkLh/fDGSxcAC5R1+89l5eQoq6lBZ6di6sVFepCzmGUcQPk3s2iEzfvBA7UpBk7XUgCUVVczy/RsOUxgFbgWtK4/JfmeXuX+c+3eiH1h5OCIkt7CeiP7/7kUAJY1q7CgQA3Okm+Yd9N1hgKuo0ddhS7XATUGwBFgskZYIHsA06jxrP+Jyclx2xrnkxnsr9QorNB8tHwJAsICujw0QwZ47Fnv6X3QOyoy4HZTGkwLAGlF1cMPfqAqZGPaupP6Q1n6y04qbjrBLsoOwL66a/ksoFuxv7IMmAcFUVrU0hJ9wFGMcmyvGtV+NhyUgWJhf3WswwsEN3nmvH5u6kBa59R+LuziCq/jPjaUZiJhfHx8ii4wwK9wsyBODDV5Gdno3z0zwyIa0ob60FetV/tpxMwUyYRaHAdeAy5BHa2h9glfDt1FIBbKLEC7GeGvq5N1tpS3LQLKTGy7BBYeUzKQxXsVFZyDLhGk/ty8gJvALQQLLwHo0cEVG1NTk9Pz4wfHKcPyBgnw8yoADLJIUlVVsNnUPn/NzbINoaukxFVgdV1xWX75lsUyAk8OHaRwTHAXnteoAWvj67bZ2anZ9cm5SRS/bW74N7Dra+aD4JCRi1zaMzKw1tO7NDjBvhDIiKKu06gaB/Omn6d+cmXIWQ7lo7PZM/Cbtk9zyI7JN47dZSLTKB+P7ulARzOa7+HmCG4DM0Cm+UE3WYJJ+RrEYA96mAfgMk4KJJ4FL92GNuaIuDqprqZO2J/HEN3a0GSdLJTH5V3c55k7fXIvoN7eXi4EI61zuu9O9n/48CH3jeCyYfr+/Bi/yK+b3OpDlsaQkPqd/d3opiOdoqXsOpI/hakudNlgY0m+mv8qJEvWCFj3MUFUAli2LdZ4okZ3N5xOVjE1fud2EzS2WjJ/EpISkGBmv0KXS31pfV1FpkpFYmOF/Z8Bs3B3pnBLD0UAZG9JGmWXHhY38JiZnZsunUZhuZH9/7wKAMEIjlrMqmU1tLfLriPuoiJ3Xp4rlxHAty2DOfhODiueDVc5dyFBBEDnMa9L+3Nzc7Y5B2pz8CX1KusnLOyvmWvqEgSEF+ylNC8Z6JWnQNoCYWmgPNeb+sO6/WdmJouZNUmK9pCgKVqyOY8VVgAMCEa0EVLSfdy3nX/72IXZ0b88ij8RgAvNcEe5ckND8w8ftqOdp+Wo4AmcYLGQGljqvARVpxOdLWiZxvRq8WpKQ0rJ6RLF/vF4sSDRc/sHuvzMEty/f5/PA2BWhwO83OSHi36Z5dd1fWVlhe/yLXlgAHfa5H5Bx44d446hatqoGaSk0OuSodS5u3db0cqSoctchSpqQApSGOTR5WcuRbbYfIiHAxg4n34+qTGp7nSdEoCcfU8Q5QEWL7vd2uphanJ+XlXuiRP8/cp3NNj//n15losExMyLcpAMMDUczqhUtr9WLDQ+Tp4x+ijPqTNDRK+Uu9TcHADCEASsPJgTrFo28KUiefXzLQCshHPnFPvLbqsDA2yXGwMDroGB2fh4S/Z3LP0q00fvSJEb57xXVobC1AcOiAYsFhf/1z/Z/N2i+9/iNujhcf8dgRD69rrCiwg/JJ9FAVCG3jJAZGB2rx4BlAMVPH5xm/pJDQgrWNKsQ5LPxAQeLj20wEJGpo8pa5jpkk9isj+6X2/sPNf0tYGmRJxFYGDzGB+Xx0V1jnRq0Oywc7SNvMDBANIcx4eZ9GPSg/KwlrVG9reetvJ4KONQOPgrVHDjT2Z1uLKX2f+2tjZN07jZPff8YXaIY7wUAA788gMMDvguX6+vrz916lRNTQ13DYJ58MOTk+J4dXd2slgWsch0mWweTsmkR72ABabR+CJ1eiZlJq4xThVUY0pJeQk+ExwxckHT07GdndQAB+lYJoAyGmC+i9Th8VAV6DWSpulTVKKSzgSd6jSkmZkVInthMOdJ2lGjtPHxJBmlCS4XE9G8Fh/3VtHefqb81x7+V55Hv/t66AKQ3bH6V+cVjJcYDn++BUBckjfeYI2SHmQ9hnt83DU1FT81ZXn82DI4yIqhAMhe0HwXDQ3sKFAIeih4oLh4kE/cG4q1hmf497/62TzP9xsp+Oky/hX2BdtBAI8rpYAhA7sh2qB+2mko6qcniH0AuxwduNlZtW63pYV+/n2yM1NAZGcdugMOe870iROL9fX66cbvTjUlxiXFrZ9AYMMAbB5OJ9WVF3jw6AGTGAwp6BUyjiHT8RI22MhrK8dycLKp5cwJ6+mKlJJDb6hSePHg0764CzTZn9TPlcDc6ZNbAzG9w2Fe7wfCcGyAue5XXnmF7N/U1MSvqAmg5iEPKWT6Q9P4N3cfnXBMSCmxIigALriWsUwxZu1sHS1F9aWWU3XWM8dT6kqsQPpnVhoyINzZZekaT+hce/BobXjiQ5AQGEJyKNtiUQKwtESXkfNHKu353LyTm0VTBswl3FSnP3ZM+SJMpvFsbJcMUakrsq2IZWKiZrn/1KlHjY3fXDybihDAUxqE/6c4K/wq8OabL4P7XwD8Kdo+C4BMEJE5WFR4sv/EhKttyn1lyvKVSVaDzPSiMfdJ547dm548fb0gZxkkOg6UDB4oHogqHkTsUWF/hDzQ/Dt9LdarUvZCoEFT8zXhKQNKlaFsl/IqN9ifxxglAGnYT9TXK+aJiaEYUO7Z6RbX1xddioiQq7ZuVfFBbS08pxKSEpNOBzExk16CrtOPk0G22ZGR2dkhOLrU0KDFQodLXTj/ouwu0F5fb62uTgGswBl4owg+UASz7xQFGSQVkf3p73OXf+7zzEmD8gQYeSYwnwpAkaioqOBQATM/3DKaD43hJxEoGFW/+qo8sIxur314+IHNxgwc1PY3miq95GRVUDnV8vDkoZqaloYGKSiKZZTZZV55CA0JPbjQeSG+Mz6tO40JQ675Gm0enWu+tmr1eGJiojc3E+1ahjujEOfZ1OtQdxZnj+CIyS3m6IswCiLbMxrgqMriL/d5Dh1iJi3F48k6tFJSsnq8kbQUH9eQlpqfmufvXl41HwSkPwQytv9nxunzgWiTjgl7P8314yXXnank5C9ZvvqBZaxBqQIlurOT0RpDe8kXMeG7+7YH2h6jwmrzsuKBgZKB1X4X3i8OPf/zwy/6WB9MVNP8fxl/AJh5a1+LPrpS2F8dvVEmpO91PJyGzwLM+dGBY/tnOMdQWzzRhATWpzysV6cnMIhCOnRsDQgC9OusVsVx5eX0J3gNiQmU7CQlkfL4lrh/bEUtgPAaj8f2WnpfSjO1QlB0NUiQ9zm0y0Hd8vJyzgWSh8LLujB5KDxHhvlMGNkv2kj9B6MBZD4eWdysCbpWKyvgVQgKAJWSBcUUCeuJH8jOvr9dULTGPZbGC4qUhYJVoBPRndFNnU1MT9FTY+jGAXympxxLjk1scriCQ77M+JOdGe9Wo9ok+xubNlME2SL4B1Niy8tuj2eKxclbJ7vwRTZF5hoGkrM4WUDGFYJ+NK4kON4uUpqIbCmbInxuEK0YptfsHBiXy+pypVomK2O+HBMz9j6GRiTrx5lC7M/yfCLZ9ybQBShuuAcxOHB4YPB3DqJcUb8yOjshwCd75yszgwzsO2KBE8+Q1zvPUn8mPluQe+VR24zgxemkM0pVYMcTlKDksHZ4DWvBz72gMdk9NYXFRaacRADoZPAyjPR5NEimZVsAeMzyzWplynZHK1Dv9ZUKZSGBa7vOnDnD4V+6/0wZM/VvCIDxCDBGA6EvP2PGTMZk6Awr74pX0TQJlaQ+vOdGS0FJWVX4Z7/Q2Z/oVIYuYAqyXpZZKRtsi1h0wikCwMweM/4yGTq4hDC/ydY4PQ27HR6POAmKWuidUwEJBhZxWpwd9lAEgKguVAZaNo+0g58nATgHbAGaqRmbbrfGdmjhJKBEi6XCgop3lJ/C5u5wsD8zccD2yhoLYnxOsT8GeKQTgeJGw/3/nCABBt7dZv8cvCAwjcc+RvMVsiUjmRbqrCPaXpgAjDjgPQjq8Syi5CXfMN63qL/CA3I9gwDsNyiKdKdo/rFDLKVk0YgdiFKvhogxEQBlBmT7z3CvwaafoMwP9opETYUdRwoBbwFIwOdPADaBxwD8rzon+1MDYOFWQJrFoltAMF23vEzqp+/PdB1jVXor6kMBxr9kfzFFPOL+0wH4POJd7/AkgofeAuAbEYx7ieW72Ddsebn/63hB0MPOgt4CEA68rQz/6aUSAB6HfY7cCvuLbe8EaoG+PYPEaqVTZOwip4b1AgETiOL+M4pE8asiAPic4ueT/XW8OIhvG8Ge6PoMBKBrWwAG8AsFQwA+Z25nNMq9BIDHMZ8U4HKJBuzY1d1rx1CRhiDcf0kBqeRm8TPDvxFE4FIaEMGLF0vM70z+vFBfREPYkA78dnwOEQ3imJcAfApMQBblk+0LtIID+gFjD3ojAlAaoFsgWFxUmR+7HSkpNIYCu+ygXeUndB2X5M8okpGYJe6/OkMoiGBzP915/ecpWIgCfq2yvWEBfgPtcxtSGUUVLNL3qQD1F1WIEURDUOUVB1xX64Bu47YTTo7B1KP+MA4DpH6dg8CUgURYRANAzM4az+xRxM3JCbvOff7Av/s/P4AmGX9Ugz6lpXi5UK8Mf3ef11/+QWURRBBBBOEWAOKECACmNqfaP22/PnPdBhttXpvnloQVqHC5LNQAJoIsUCPAPKrZgi0taqegnh7qg5q6VVDA0WDz07FmMDOIzAFcHjQmoGRnIzFx//Psf0JZBBFEEEFEAAQ4CX1L79js6Njq6LjZ0TPTs4CFaUyPYrQPfTmunCfrAOos/RbLA4s2+zGGhtDZqfbtfvAAdXVqDXBFxe7T+yp8uf8ZyiLBXAQRRBDBC18J3FGvdWyld6Cgx1KDVk/nQCcHAx5rj7lT5xH3kWRXssv16yxXHlrW2jA/rzI/8nSS6mo0NlID1KxQ01gCBoEBdYwggggiiOCFCoAN6KA1NDx4suxaVt0t9PXdmrzVoXUcKjh08DcddLkSYq64Y9buqKWiNpvK+F+4gNpaJQBnzwb0mEOD/TfwWSOCCCKIIAJN13Vs4wfb1g1gdJTpHZXcHxigp69PTzcvLn7D6fxva2uXLZYP4uIuyLY/+flqpSIjALr/TP68dIgggggiiEQAD8T9F/YnyOwczi0r05non5jAzIyLezI5HJb1b1ssX46JjZVdCRkiyK6EkYmbLyUiiCCCiADMKOoXDfCCpumyFQmzPXNzrrFl1xWn5TtXLd9MtMR+RXYljHj9LzciiCCCiAB0bNv8rsssrFaa+zF+thPcBYsFCUAlXlpEEEEEEURwAEDnNvt3+Vxkp9FcLo0LwX62ExwseJkRQQQRRBBB9JyR/d+d/eugcBKAy6UsweW1E9xLiwgiiCCCCKKN5M/sLuz/d409HLa2FPvX0DZRjvJMZELDS68BEUQQQQQRAeh8nv0Hn9vAgezf4FZGkP0TkADgZdeACCKIIIKIAOz0/UvwLOJcKHEBNC+8vBoQQQQRRBDBgQ5g2szWqm5gVwEgNLyUiCCCCCKICADMOPEuwK0MiGhABBFEEMEvzFYQn09EEEEEEUTWAUQQQQQRRBARALQAfwYoAjRT5oUfAX8cOBbo12DuC9nA7wC+CTiggFd3ntIkaoC/CfTBBLR9ts/gGsHDiWBxD/gHwLvAwTD91uvAHwKOBHX/2cAfAW7ue+2+ppoVbiMofAj8diB5r2sUAX8aaMY+oVj1fbSGu1v4Pksc8JuAXzX7iNP/C3zN92lfCOSXHAX+AtARdGF9AFx50ZvBhY4qYAwYV4ZVhBtV25ZorE+bB7r3ZzpSBMPAgirkoHDaa8rANXX8hUc90CCGwOEBVoBlwI4XiG7sByLQTYrVyy8AWUC1Yn8lA3cQVhxTp1ZWAcBbAGjTCAQTiMAMepQAoARIQVA4C7i8NOAXGmWK93GKx+C607IyrOAFYgpoRQT7pwGE9osuAEYQYMQB4UGS4f4/53MtKAHAjwCPySBgALiLCPbEgJcANAadWRQNkFDgNn5RccTL909DUFgRQwgIKQZeV+yPFoQf+xib6y+Bf/9ShALRz6efWoAheScaiYlqx/+CAqT5bdvGKeKB6n6Mt3sLQApS6lB3CIdgDhsbuHsX09PYRjWtCNWnkOn9fPnK7Qhg4VlW14BvYDd0deHOIyM0qQGOwg8uwxw2NzE6CpsNS0tYW+O/UmyqwLKykJOD8ICnHhtThbK8rApI1+H1yDajdsxUkRn0XEXvmirbEmWXTNXd5R3XiKMGrMB1Da51uMTDhAYtDWlsD1ZYzf/U68A0QkQ2cM5E7ZrA48fo78fKirR3of5TKC/ECVPFshPL7VjuxzJMopBX9NlcDYr5Bkyj5QZaprwjgGKgPpRuMYKRKUwtYnENa5vYjEZ0EpLYinKRexiHYQLNuw8CtG17FwfykS+nwvo6hoZUD2SNuFyIikJSEjIyFGulpiJ0sLqnprC4qC5ExMXxtKpjFxYC6EGPHXYIYFG8so2GvTRgZgbNzXA6jbINgYbAJtk/MDCwurqanJx89OjRoqKiYAXA0AAyGSkmMxMlJaiuxsmTptilrExR1dj3MTaChyDykMdG8A7egTm0tuKTT/BQfZfItaLqHVRVoWpnqRhZINoAnuKDnQXHkr5zB8rcSMIJqaiQBeDRI/T0qObHFrKwoOpSBIAtkMzMRsKSq6xEXh6Ch8eDzk709WF4mJcRnVECYLEgOdl4IpsqoZSUsAgA70jZPREA3kHWeZwPRgAI/sKzZ6kBytw2PABRhCK2hzfxpumfGroGZLFRmKtdE3Tw8cdoa8PcHIT9UdWA108I+wcnAGSulU+xYjPF/jRTzfUDk/fKjsYe13pTCUCW1A+Kg+4WpP4udA1gYAIT85h3wsm6jkFMkpaU8aOMAhQUohyoAp6l5je8//RTYoOiAVGIakDDe3gvpmeQjp3S48lJxdEiAGx1ZK3SUtUpyFpBY2REdT2enITG7s1+R8THIz1dqcvx49212T849ANKHRRinmtjDXvFAb29bEo8t8+C/YYdOGiyz/Z88sknHR0dCwsLhw4dqquru3TpUgn7bpACACT3osIVPTObskAHs6KCaqUczzNnTHVZqsX4OJR9nx7rJVzKQhYVuxKV2AsTE6pFdnTgww95QYpG9SuoJvvHIQ47kPSsBizu+ntcLqF+GiMLNpQTqrOGCDkrew6bnzwxE/PzcDiUAIhuigtSXq7u6PRpVSTBgCxz7x7a29HdjcFBnktdRgQgNlYxPqOM4mIcO0Zt4GUoBiEKAOWG7M+m2fMp5mzRJXiXGkBjDSK4KINKqDTAJTLAs7+BN47gCJ3BYzgW0E+9BswEyf6XERZQfVnldCZ+/GMqQS1qSf1kolM4FVLwxahO2fcAZ1DsH/zFSZuK/Wk3sD4l7E8LEg/x8DZu38d9+g9Ugtn42fjk+KioKJfLpS/qWVeyilGcicfAGPAbYOCLAEwJgKEBRXoR3cql2y2HWRfsHXTESNbkaFIGBcBqpc+lWMtmU07ZuXMIAqR+9vD793ly+l4kQPY7ht009m1xc+cWGh6ff3xVv4qjMTvb2N/fKxe0uqoa1Ecfwf72Lp/Af5ZTmhWAlpaWH//4x6Ojo8XFxZubm5mZmeYFwBuq9PjFy5dZmJ7x8fn29vn2H40x/GHsozozdXVPMGtE7SUp0m7eZLOg8lMAeGQkuKc/QiOrsirJ+2JlKIMPFHhpwE927VrC+yIA9BHCAdLvjRv49FOeWLUQNrNsZJch6yAOMjhd96zPL86PLo729q4NDZHDWXhslvQYAmf/69dZgGhpwYMHMQ4Hw7oj9fWJiYmapq2trc3Ozo4MDq5SG0ZHeWuqyC5eDDHrRPYXy/lb9X/wO1n/82qPbwEwjexs0QCxrsddZH8xlhhM48gRmvn0cBvwCa1ztRsWi5LlkCFkSSP7k8tI/WKxiEXQYK2trNBIVdXVZIKvK/ORH2Oqj6KfkBC2tKLcDdtX4p8r/X3fzP7o+lgI08aGb+HWNVy7i7vzqfNVVVVnC85arVYRgLm5ucetjz8c/DAJo8A//rcH0n4v86S0HdL57+Rsfi+VgQzHDYfjxrXDt28rsmBTYj2QmlmYlAH2OqoCO4XdDk1TV6mtRUAg6bN7s5PT/aLjxfOfOqXYj+7/1hZPq/r8T35iX1+3H7DPvjbrQLbZwZa4pxpAf1Fsl+b7TgDsz7TP4uLi1NQU2R9g23w8OTnJUGB9fT2OpB2oAJDh2cKoTtROeoIsPYdjoZ8xL51NvkczA/L2+LjYzIiKCikAtDM44599WJsUAEZdzBFXo1oEAH7hHQS0wws2m0H9tIzkf13/3pXvf/f7YeEBnlg0IHYj+RLqK1BBlyQFKQxOGfbOYGYQg+1oZ2KO3Yzkw6iUfgObEMyPLdC7uXWLGsAOSuqvvXSprKwsOzv74MGDFACn02mz2Zj1Y9z3iD9IREZyTwwOggLPIe4/j2eys7Kys28fvvsbZ3+mAaw+BA0mTN1uEQCb61rX+M80oAlNMAEWHeWTR9PsPwDc68TdT/7y9/DaaxRFJR0hoq3NEACmsw32598IBcL+y8tRfz3qOFIqkQLabgOGQmUM9uh9hgXkfbHpq2lvXqmvdwx8hODBPt6GNkYAi6mLzD+cPn2azTU9PT0mJoZMxLb68OHD5NvJzFSc/g2nexNrf5KUVEdXhpoWeNWstq067jhWb7SoJvveeygqUmkZEYDpadWCeVdMI7DjS8cj9/BC5h0vo4fThSX119erWD4zk8xIAWBl8XXPo0f227ft8QWORAfM43+olQ+E06k7HBppluczoBvjOG/DNNjdY+Pj4w8+gd1uT01N5TBAQkICXw8mAhCPzQjfGaRQAvs/GqOiMmLkzSsnZE9YLEYQQHu49VAEgEGAL1+SekPqFyOE+qkBZkaNZEaQ2CgUGLV5Z34KCuYbG6/Mn3HhzwK/D6FgdpbRIR1/xc9k/4u4SFWrQQ1dwnSkUwAo6kyA8j6oB1vYGhwfpDsi4wHmBYBKSC9GOig70quvvsoeVVlZWVBQkJKScuDAAdb0+Pg4O1VaWhqdrC5+nvUiQwLMe4bm/sfMZeXm5ubk51qLinrCIgAyOORyiQx0XruWM9MpGmDmtIzmyX1Op8l5IesP8eD7aL2He3P/LkcNkPDSVKAQwOZksL8FFoP9WekIDZL/oQakfMD6SzmDlHzfk0bogDK3oWmhzzNh+zJuCK866uscR+ucDxAsRjFKj6cXvY/x+NVq1VZfe+01ZqLZMrdlboW5aYYCVILey73lieXDiV+oSyzVk5O1wKvG0exw3Ot20LF64w3U1Sl2Zsu3WKgHinDYOfm3w8HkrGIT5kj5BxOkJsGQWno4T8XQ4ZVXVBKppoY9i6eVmyEnOnJyVuPjV7/1U/wDIGBJFt9faUDoc5ooscz21NTUuN3u+fn5jIwM/s1X6CaGOg2UHZSyR3GllmwsLFANePOmBABguRtxwFpHh5EI8iUABvszm12IQiP/AxNIezYOcDCCM9j/wYOKCr2xcfrUGfeVM27UIkRQDvv6VCNht72Ak2R/0QAN2vaPSWM0wCiV7D+HOYbGvb2bpLCREeVJmFJll4tBEONQ/niKeX19fVNTEzWg1Cv8YiIo8wmio6MdDsf09PQsy45ETReRoxzseAGCzojh/lehpLC4sKCkgNQ52Nvbs6w0QAyhoLJSgoCN6OgutzsXP9MA5s2wB0h8ZqcEPkDfIzxiUxrRRnDpEgWAFipHG2S5uNiAc8L+tSE3JmETseSK5BRdaUB5SBMHJ4FsMyNtxg1VrtfVNdfVr6+fZKwKDUFhHvOMeun30BXNz8/nLBQ2Wrop2AabMVlpaGgoLy/v0ZcfTelTs5idxwX6TEFMkl//I7aN1x0uVi7ZubERBuihUwyokyxSMg95n92V4i2OPH/PniDL8Vu9vYqJSHzsSlSOV19VaW2vm1E+1sGDKky3j2PxMQLC+8CvigDQVBXroe6qyZs75fF4cnJy6BfSQSwvLz9p2guM3ktelFFrN9h1xYMzDRkNliCgd6GX7C9WjnI8i5kZSf2rI51o8f1pvLhZ/9IQgLa2T7cdf1I1y+HMGTaSraUzm5vlm9AQyBDwBVmjuX10M17jDZHKORmEGWneCEeUG9FosL8B+obsD2QiEtyIa4SBKUOH+XmJrkx0UF5jaIh0U1pXd+zYsdraWrL/bgqdy7fGWLy9vbO8ZX6Lv29yknwZtPtvWcrgfZUnlJeWF1CH2B967oZJAAhpl/n5g5ubXUAunJQBxk/hmhC+hjX6oX1aH4/IUe6/RABhSf2TTdgmDfcfut8NcXWz6iLGAf1kJNN8n8UMSaRiLzCQMlL/cbbCerolm/V1ntuax1OEGAQFFrsTThJaUlISuZ5ZCLL/jpHBwxwSYJoCgENzOHXnOtaDXCtVb8WpEkX9tJ0gx7CzMLBgA2BXokdpsymKoTO7J4SvqBns6nRh2XjotZD9d6L0MFY0LELZiMlSWnduM79z1el4AgC3Ibi9c1XVQXjjLHyAzv7Zs2c57sLMMKuA3mHYFoJR5MToVNJMqaj3oJUxGHDtmvdo8HOzeoT6afRDa7Z9/6IAJyTUbW7O37mj7O7d7jt3DkyMnWkS9lfH7+QjcHz9WQFYmZtbnplZmZ5ejltbyUQmyZ3Bii8HlgpBBycVqSMYsdtVtbPvmQKFgnLBhgvQxyfLc2QfPsC36FVlcYSG4Lfm5ujFBCoADO0M9/8kysmatOiKIrI/bbS/v2fhZxrA0Y4waAAN6ARyty09TGuByPu9Wi+PC1jA0XC4/+3thgCw3f6M/fWGeMT7/jnBRAApqEjRUhgEhLYIKg64CrwL3xDqp032JL+J+jrmUPTcVIQEdgExfRvYAe+31Ie1A5quBVmE9cpwyu+8AyaFSNwycW5xkU3clABQJ6gWdKEI9qncXH/JwzpgEfgz/lJAbYBDGZzyBz50YMapOTmG8QTOPwZc8cH+NJgTAIEMA4R5JfD6uhpZoanAKi5OGRBcEDD5+LExGuw9c25wUNhf5VXImHSyxBAYVi1Rd+qK784P3pmPvTPvmqu6JOyv8+gRCddCFQBieXm5bmmlBMvUQ7J/tu+I2wILLRrRMr1SdNRsOsZu59XoRrFGGdPRdYIPMOjmB/gx/rHGb/G7DkfQ7n/i6hFhfxWlxUepgFqCgFtPgwAJy0LHgpcGXAyZ+sWvJPWLkQJCd/8ZURnsn6pbhfp5pLSHbSKORADr6ylQ7M8jQoUVIKv8E1+TG0n9ck9NivrrGAGUwGOu1H2664lI5IQu/vgZ+8zS0hLn/OycgsLsP6emsPvI4lB+PlFLDFI1/wXUYF68nzKwsjhVQEWwU0i/MOkKUS3oQiUl0X9Vo3b+KfUN+MeVZ9hf/r7mwLDj1zucX1BBgLC/2kbzA//sT/xjhIIgBEDKjabrSl9YoDwGpNhUehkNljjgoetpECCju0wpGVM/CSP1T8cZAWAOuEPLyrpTX39nYcHBtkflFvefVTmF4JBJ8ybmhNWVL68ur6yusNfSi2Gex8/vdMHlhtsDjwyKSzLN5BQgKgaNAkCokTS/iNoGXC75YqDTTQ33v2Gb/SlvACgAEgRM9fcbo8FKm8MEEYAcdURpaOwPDX3oE1vCEo7Whur+2+0G+0fNLzXoaso/zc+kZA2BRQUy/EvjRNJkPZm0mIAEeltSg5o0moADjFTA6iu9YWSzKlwnSP00RgDAPVNF7vvFDC1D1vp0bXQNDw9zWjojV6ahmY7Ydqxn7t+/z0lxnKqYgxwOkvHzvN/gd4nIhj8Y3qq3D2smO+ZwKL5jB+RwAhMp8vtN1rcPATDYf1PTyIf8bfpXy64D35jGlQMY/+q3L2+evnwaNM1LAD4zRJsITxWBiaKyUAJukQUFRhxgb2szggAuEAOM1D/fBMklKPdfNp8Tu1tZyWUQnDVI/WamQX9KnhpCRlL2Ki0b5pyJRSySiVh+AAuP0um7Oe1gdI660Diws7GxwSn/HN+P8aEejKnpR/AzhLqANLKg3P+UdTWqQSNxGlPMngYBs4+MIEDxVDigP5sIiguW+gk6Kjvdf1roqX/ee4N+RrH/akP9ag7cY6wgEgTdTA2mUA7YgGU/+Z/+lJR7KclL8bB/i2GBRreI9WixGGvK2Yk0s7piVRqAV4Hrz007MVL/MdO5Qv00UXottF13jugqcKTfZtNsnJfMMQB2Qg5NceaPTAPlLPXu7u579+6N94+z43MNIGeUB7dTkKlvsfuIBRJ9GzOVjcFPWijsTww+O2GTxKTzV0mK7AYUvv1t/J8o4Ks+Bv1ftABIhKoITEwB84Hue2VMCWUQMPN0Sqh1odiY/GOBxXD/tQDKoc+gfmOrEA7d0/YFq2Im2pLiibEpTE1jmqKZlRXIOgB+QeKt2VlGzQyoGT4z0e8jSzHC3kUPa1Pclvj4gNYB2GxP3f+m7ey/kILACALmGATYfhYEkDgQJox5aUBDoOyvwYDB/mywOHoyVPZ/8MAQgOOu4w0PGxpGGhpmRmDvIk1oFADWUXq6oubi4j3rlZ3btm1TPO4cAf5WSspCUsriNxl2aPRDDQFgG2Aim92FiazKSmOlt18xSBUN8JX6H+2NfxOK+uv1ekbh4dpzjSP5c5hb19ctvZbrvddn/sYM5yhTCThLjU4MFy0ODg4udi/KlDle3XcgFSYN0HVlhKbJ0dQKT29oGi28e7vpHP2qqVEXuolt/DpcBiAaAPy8CYAk0LwF4N8icPCLxv4QH38so8G0tEdFDx9qZH+m3eq3ff9A5pt3bFM/j492lvYLFAC61GTNIQw54DhRwnwUO69p15zMwm7PMavBQbpRnDzHmJpDwTsn9nLWV2dnJ6cAcfkfiNRUyX4G4f4f8mQa2f/nnSkJApQAtBtBAFsDwgIfAmDS8RewkTLzIwJAsQ0x+0/dRUeHmgne1pY1kHHqw1OnurMahr6XNDWlka9dLtnvSaiZF2KzJaOaEQDF/t62suKUCOCbhSkL30xZXNRWVrTNLRLPFrZkXqNqBkVFqKjgyKRsKrIXDcZva0Ai4DDkzEj9N6rMjzJWdLjYX2Y/n184H9Mck9aZlt+XP544/iDzgeN/OjajNmNcMcn2ZOZ8mtB0HMd56bM4G4YOqvtdX00RpREWi2RgzUTeYt5p2DDu76kbWfHnGnEU5PIvJAiIlov6z4khN4ktnm7p6yHMATfWhXFWCedHliyUHOo/2ttbzrHfDGQEMvFfYFA/bRj+oYWJ/e3qiC34B12hTnR2o5t8RDY+dowsYXYNtczuVMxC1/LRI/pNpHiG0vSkOM2Lc+mwDSZb+dadO3eYXeXfIEgWDDT4GXOgHBvu/6vb7L9zUpORBVpmImjiZ0FAIxrDqKqiAc9CN1+bQv3UACoBjtaJAJhy+nytkurspAZYZmfrfvjFuvbEUw++Vz84yJH2Y9HRTMdxJJMuLYMARc1s2NPTqp9wTroPnNqOm23P2fIyberI8szQzJX5wz9G8ZeRRLqiALjgojJMOaco7etU95ER2eyMRKbEgNg7C0RzAKrPGdmsMvdxet9iXsXpn17N7UnmdGbdaH7rxq1/3tKSmvrb33t7xl497/zTzs18tRkch3wZbTD1z4qp0Cv2fTtocpYxG0Jyr2ZmRjJ09h45oDGt6h+fAq+E/HvDt132FvDNbdPNXT1aPrBrYxARdbmUiqrSoYUAIwigsa/2P+5fHuReBuW8hPj+ZH81D9osfrrN/tPh3i9cD8X9Z9dlqM0tsR7gAZXg4knmo6hsAaxFZ2mTc+n+s6C4M+rdu3c5wMsJSBQDLvPjIu+trS36/hMTE319fWT/27dvy9Q3zv6kePjYBbfKl/s/3KPe88r+74CmkXQoACoISJ0pwc80QO2CECb0PCMAekBazhyKCIDh/ivfn8egIKooY1Mu4Hu/53vDlZU/LSv7Wm0tZ1sxo+1yubj1CpdhM/Dqp1RMTKhIeWuLxKEGiX0jXRkqgTVh/9VVm7YydX7FVvrlFVv2EduRNFvaQdvB2LFYCgBHLTmAxK7Cm2JbeszCp1dL9pf13juq2EcWaJw0aKT+tZkj5H1x/2P1WHM94D8BH5hUTY2XuXHjfNTtxsarr702E1235Dzg3NK3mIxPRCJbi+kdpUzMAuqFvwBGFt0sLMhkdImMzfQ7cXNVHtVul+wcQwGfyyq7gJZQqF/bVQN04B0EA2re8tracmLickKCHkwKaIcSyORe3j7bN41lEYoqM2EqgwHa2NiU3jw8Nrw+yvyGTQ0f2auqkqoqURmII/+JYn+s7P1DtCDYP3gB4HYo3ISgGc0d6GDGj72N7lZNTeBiabOp9ufx2FtafvSjH5FxuA8EN1fhdE8KgKz+/TcTEx81NFh/rfWjP/zhFlmPtFxUZHInX8YMJLq0XlweAJGJTHH/dy8DyUGvrzvd7h6gBCOUAdkmOoyJoODCOIP96fXhaH2o7j91l2zb1yeL7M+dO8dllsePH2fhc9cNvsKMNhfcMy/HDZr4CuWZWzYxV8PEHTXYzGZ88UARLWkFX1mx2ZZttt+wYsvJtGWm29IpABabBf8PHnjmMc8UIjOl9Ip06ENjQwxKlMCXqDVQewkAzeqd+h/qi3lTpv3odSRi35kM79p/2+SeZJoEGiy3jo64JpJtQmpqYY5LaeK+oBVIA1KBDB8L6RkwUZjZgyiZ9AlkTYAJUCpk9idvhyrCM/A8u2+yO25HK5Rlhsz+OzTg+8B/DnR/SnqB/f3LDsdycvLysWOs6hDHAHRATXOQOQh0eTAzQ85gaVIeg/a3ZV3YL4+PX8kZv/9nx91jY5vnS6ovv2M2+aM/FwG49oP9QxEAbohIAaDdxd3jx9U8VKZtT50KfGsGTeOXqbiyCetWf//DJzv/kP25x5Ou68709Jmioh++9VZHnaOjoWOLQyqs9fJyn4nvHX7ceg/e6AFoCmCQngO/5MWtRgsL6QcoARDDVNh8OmA6qAwe3WRj9iczYOL7KwsODocsBIUaUyHNNnIHDu7DwRmNjL3gBeoxX6EecPLVA6bYmTJiFfDqAezGukzLzFzJzPwKEIcVr4GCs4j+o9FHcETWEpL9F7HI5KmHMsdaJrvV1flNalslAqBeGKn/U4r6VeaHHc1fNltHENA9HtKuGr52Oll+bW0aNzkg5SYm8mey8fNIY1vmK4xhyMb8W/N1MrMCYLXjgmNnbocixNwp1Yj+E3sE64WRsVktYpGzFVHIx9TuZ2wG9JIoukbi3qh+pfr37qNlFDbgIAKEFuZcECv4pz9Fc/MScfgwE5SKpUlAIQ4CFxbqLMDaWjhuakNs4snJmJpSgRJeB9KCebhGUpIxI6j/j/yIWfLT75yWjR+EfczDBPsHQ/2hCAA3oLiJmzTKQP7R9aYm7oJMGieBB3VFlvalS3RJ2HzloTNs0Gsu11pUlP5kBPIn+fltR6faT9ycKJrBF77AgqWT7tvzrYA3BlDRA/QCwwEkpoRY3YChAeGi/6A123D/HXAY7j+7a7AqNK3KeXKSOldYWMhtNrivGTWAurtzEw4qMeMwTsFias7R3886Ug3bIZRk/lGQHRAkK8NRwA3YgD8KAWfL2GDjEDxDgcG1Qf429SPn5pQr5hMJQOroqLW1NaG11UlyKHKXGckf+EDu801SA74Ac5ANb/Un06K03glmzru7NbbcHQJAAqAAkGPJLWyt/BKCQec0rO2IT2Y18SxKdBUpgcVCT4A8SAmiJJMEZfyNMVMAw28UjOJieQIHT6LESuZBMDJgu1pZUcLA12Wz3vz30POPgT8SrsZtaMBvD3TFYlcXd6hettuXjxxZYrHyrkMXADIXm8z6+nJS0t3h4anpD/+OanYxbyOUpysxm9w7hoxxxIxnux9VIb0KBaSufaFsLXynMgRg0if7f4pPb+AGBeBI2Qo3EKRRA/LzQ5Ao9hgKCJsv29zMDBuf7nbjyRzE1vT0lpwbrYWtbVobowyqNNNMbLhmb7dHDMHBEABaPl4YFrBgCAB9tzDM/ZdVoOQRgBke7sPKHVgN9t+5uQ13PeP0ds7Q5TQtGPs9mRWAZWU7EQPkefvkyEUuE3TMoQ9iEEtLsnzMrwDAbif7pz4x59b/S6//RFF/Curuwfht2i6t8RPRJXzy3BD2QQguwSfYShdPnhzc2PjWo0e/t7W1RYtf+3SNzCkCwD8sFhKyKht5oiKDJWrZ+fNBbdT9r4/gWjZ9XlUU9PQZnPHUHo8qHHmMF/NyLCIOy7Nf0DFiWZkEU3n8ZbJ3I/md5+GvZ6vgmBCFS9Mo8HQRZD9ItUlc3xmAFlbXJtDQiCrIeyczkP2BZe5Us7jIv2X0ItStIJIrx6wJtw/ldjomRvS/P++JSeI3QkY1MA6MVeER/6IlvshHNush64dif1K/WHrpIps1jQJA6g49OiHTMJw2appuyGD0SAt+rCJ7rZWulOyuw7Zu3m2GuP/jwU9L6HnxAgAj+bOGNRw9Far7T6ytydQ3LsAmv3OHpXwKuG9wvSs/xpEAmTQd4D4cZp8Er3ZNQKJafGesa3W54BcjrakdLVbOx+nrm3jrSn0q6lqUyb1ou9b0e8BHV2AHrsCAseXO3gLQ5aloT/H0FqaOaGVfP3TIUXbEWep0lbrc75KZlK1jnVHaHOa6YYuN5SCXKiry9i/9EgJGE+DKwKceXL0KVhAjD7pK5DvqAVWFLYJqc+ECA3DlGzHvFeiiJXkIMMuZ0dMPf8iUIJNCssqSzYMyz8sp9q9pQl8jkBoK+4cONnh5NvhabS23KlvOyWGSAGIhRgCsMI5nXiu6dqfoTt9Zy+q7775OuolByMgEqoDf/kPgTwHlCDOuARfMaoAOA8NAIYKAsL+4/9biBfH9KQD0JIKmft1XTVss85jnqF4r6GS1LCa6hPppZtcZu0N1/wWDz8QBLwAsh/C6/yKxYvT6OduKOxlQCfyu2EuMfwKZM+dz5vhvAW4D/XgGunr4l8mt1jRoNACm1jS1I5VTMVtTLa1WAG1X6toUkdcCmg9iOiSPKcEVYf+3gTlhf5o3/jV2x/376uFI9+5VPXz4/mD1+V95553V48VrpWuuIpdH97g1twsuCgAf5DJzbab/p/3N15pbWpbYYEknDG7J4YGhBvAAUReZQmK6n346+VqVv8ySYlKIfY8KU1/PGDzguYskd8oGJZYqQsdrcFDFdszvaZo8I50np0goXZlvBLIBDSjbd+ov2GuS/dzcUmLikt2+lNmOx2rjgTAsBHuMx91aN+mmLWca77/PYUB126q5hyUIUHgT0BF+/AHgX+2tAToM/IMgHxzLwV7D908pWiDvi5GITNxZwOKwiU1x/FkpQxhC7Tlx/5n8Cdj9tyEkvGgBMNifzIKjDcL+yusJAWQQMf0JONsKfqFvQ/LgPt2uC4AFiAG6fdCC7o80GN9wVihN6InEpMwXRoBWWFutFICszay38Bbm2gDa3wP/3rX93QauPMQV9B/HZbR/wNECYxagppnYQFOjAHDs6/r1WNu5d9n6L7EDcM8D6OR9SiLdf5euBGAFK5OuyXZXO5zgxDby6sKC8tqDQT2QVCN0rLz+lRVKrzyPm96ALJ1TXhFfCQI8gwy/FRQwFyQP4pZHsjHdRNVSJ6+qwZWkz8jxLwWa4A8shzfftJWVzTl/ZeH3L+LLauJTaAKggZjF7BSmhjGMjBwORaoRFR7Dg3jsMzKAGX8aoMPA6eDZXxx/HpMLDfbniJGZtFIw0ifUL+sMFN8Z7r9JrIXH/ReMemlABT5TsGUaAsA+GR73HzC2AHOOj3OAl09b5XZM0b5JhHMuuCCDHwMgq414Bp8CINYeMEvwZhewsIQlQNbk+/bvVoBWZYmtidVz1bIqxZz30f3X0B1zGUAtUAbpMaS80lJey/8vJv3SP2aS3Barxnb1qioZftSgxSKW5t3OqxqrNmY2+AA77hW6ubnOtI0e9EZA5UD+F+WJ7bDbKQBUX1mhTZpSpRQKmNZ77TXVoiYmVHixvi77uDHdxJOrSyyHzu/mUAE0KfOP5bSo3rS+x7GPx75YSv0zH1VF+2mLlG6J3YxR/HDO8/A9GrX/4wHmr2bK9z9YIJkfnceKihBcAc2fS8hkN6lfDFYreV/cf/aygN3/OYQBL04AjOw/2yd7qXn33+w0cIBrfbkFE6d7cjoQfIB7W/IB3NyISYZqyA67L9Eq2Wb/GHXEPZgHb5AemOwrBYuFvh4v5GtimbA/WoB+sGWwUOiAm2F/JQAw3KCTsjerTgVITt6zKTscpF9FkohTo73+W6PL5eJCCq6mprKyCVNcKJrBQ+b50PYJubnK9gfGVkMSJDHCo1hKaKtDr5AuVbXN/uf81QOzlkwMPMCD7lM9y8e/QA+UTTFAAdB2fS9ajOoqA82hRzqhf18PyFHYc0xYAxqCZH9x/xPy5kn94vvT9Qn4xjRTL85gxmB/O+w4eUnc/wAaqD2c7r9gSjQAnylYFPvi/gMyB5xFSmbhLnuc38lJPhwK3vX52pz5w3e5xbHah4NeIX2unByfjmeelwDQbgFbaEYz74V7JBzH8SQk+aD01i50UeoYBKD0uOwqtXsK6L6ifmWtT7fpN9+LxoEiq/F6ivlZFLJLAKkY8wuw2bhzeHpGhmW3VAFXs7e3t7PcuMNVXJyHt8KSllxFcEHAi4YWinLJnChpzyMY4VCiFdZpTLO6xfmurq1+yv6F/q7JhsSvt5S1tDNFLxOfTCPaz10kIIHGZrQgWwLZ7T8BLuNlh47QwIFxw/ePz517Qv1uWlElnL6bRxzifD/81tT2EmJ0BtWYj+H+AwG7/0sIG16EABjsz05isL+5bK8JMiMtlZTQhxpub+fOxlx6zdVefJ6t90IwPniP+0C0trY2NzerVWCAqfnmR4CLT0OBttttH69//AiPClBAH78c5YUo9N5izwYb32WNy6pyJCfTv+AP83mV1m3bCrgHaL6I1YQGsGBkU9TBwSW0t38rMTF9eTmdq9YPH+YgOXcx4VAKd4Q29s9guVEGTp0iTakyS0oKjX71l4z6jQwTyy0rSy0160Qn652JPpKtLGzMRGbWqay8pjxrk1Wxfy78YxnLk2WTM03ZW41qrz82lfDsBkqvhFPQaFhZpHwrA37vz4sG3AziHePtWdrz9Zhj6Ow5v+wvjj8tLuf2+fM3z59fSDlvb61yt/ptHixMEnYxihE4DPZnW2HDMeZ9BrDhwWL43X/BnDrlZwe6SEb+h8kQ8xt/mgUZlp1yfBxzc9zmgQMATPEz1ZOdnc3N4DgpiEt/mfPhHm1MZHODezqzaGhgdZDP9l5wlCrjARixjLRZ2qgBP1r5UQlKKADUszzkMRqgo6BDd8BBARjEIGucTW7V4sLpV9VVTpygz+xPAOYDY3/NBLHqfjmvoEAJ0+SkPG244w85HF8bHk7PyUlLT+dMKkMAuIMeU2qPFbpOn3adOcNi894i5SWSAQ0hg1EcGwsdOaYP+/tXPsJHD/GQKaBVrDqtk1VVJztP5+Y25b5y7hVkYk8crz2+2Lh4oNF5oKnpflFR2LaDpi6JYXlYtkYytrXS8cLxDfiCB/i2D4fmDwM//cbsLl/OFV3zLwDMshm+f0zW3z937ttZ56bvnpu3V9tdcPlvGFnI4hyRIASgG92GAAAg74v7TyIIxv1fRdjR8yLcfw88hvuvBqjCBRlcWVjA2trGnTsff/wxaYtZiyNHjtCfFQHgQxooCXRmlxgZNzbKfHOzu68kYfWCq80y3GaZa0v0LN63tgy1kOiLUMR8cypSRQCccNIlHMUogwCVz62/yKvwWv5mtbcAAwGwv2aeWPfiWFL5+joTQapJcn/HT+4MaFo6n2PKCbJUUAoA8/7M/2xtzeTnb3LiP7WSpcUbslh8FZLA9HsHATv2Hwd3/oKkYKebUfyWljhuRTGgs7Hlco2wNHLSmE1ki+6src091piHQ7mAX0KPAhqR25j7SuMrBxpdBwoLDwCt4RKAZCSLUdyNh5dyKPiFhl8GrsAPPMB3nmnJ/xQCzB6+csUv+xP/zPe8WAbjZP85zL079duHzjfcPT8zVzPn0BzYC1/BV9awRtpSYyqmMYlJg/35dfH9xd8MlKTF9gPL+Iwwhann5/7L5j/hBfM5Gxtq1gej366u7icjAdwKlP4sh0XJZcxmbLEH0/WtqFDzzZnOaGpSymEObRZL24ULbfHxA/wKswA9PYt8WMr4gzZPG9OtFlhk6uc61tWQclEdfw/ZglchZfpb5tZqlv21cPvXdBI5ZYY6xfzZ8LCKBrhf3urqPEtxa4s/mZwhz7aRZBFviJGMv1u57PNKvt/77cB/xn7it++8dk4I6RCWA9mfZcI4wFjGwBaRnc23PJWVnTExuQAtzydLH1TsL5bdmP1KBg5ADM1hEQAmf5i4oD19fJ3dLgKww79+DwHibYSIGvhFvQeYhYGPgIPqojU4DLOohcAYaudIvVrNCFUxV8EG58Z/VjsvohbBw/d36QYK9beicwpHYMlTvC/uf6AQ938dLwF8N6Xtp77oW/giGyZpUVEw+03YwUKWSd8MqIeGwE07l5a4167iM4uFwiBzDSWMN78Kj3gItIkxaOD55Wlfwppzc5x56nC5ZMYhyYAiZzwObO90iW7q3fd9FfBJZbvjfSj86h4TaClP1OKxMZaWiqAYHRkCEBuryuzQIeodRWLvmT8fYDdYfb3h1cnfxv7go53XzpWXQkBBAU22/RUBoEyyzkUah4EuQDTg5O5DSo1eloRM4BUYGoC7oQsAUxYJSIhHfCxiN1ifTidtD802hy8geJi5Yr2ykPFByOcO/ipG6v9hK7K65UN0GEg69ARTU4MRANpLgcs+g6FejPahhiZLosiMKv28T+DJc3MVpclGTBL+6jq7KeleNn/+/+y9B1wU2bru/S8FGhAkJ4liAAOimJ0czz5p9rlnNt64z3dzzjnnnHPO+Y4n3JmTdpysM86YYVRMgAhKjgJNqu9Zs37UbYWWohsanKlnv7umraaraq1a63ned721akkezNY3uj32h2kQF1qfWacwNNDfL9a060GqdPa1mboGOYQihhV57uG/QeNy2d/C/vjbS69lJwMV4nEBUJ0lJcXhHW5cHXKP9YqyVu5yiouNRV8rr9xsKSASWx9l/w1YFD6qAZ/EKQDek6BSAvskaPQlAU7GXpcrLQANshXJ5TTGz/6xl+MKt86x5TyN57DARowxPjbRAjM8HTgZrQR5LZxsAdcbRhW1rCrS0uxCpTb29QTAvtJsudMOZiLY/wERsDKgniW32S4I7PnMHu+vBPuH4aS/DhM/7GhGfAgwFLFe6ks+n2HMh28as4hbAOy7UVxcOyUgeqMP4RshVgSZPr+IHdt5FBsW7Fr5s1jchXNst3N6pp62RK1/+G8f96CFUAvcYC1gc2HxwWP/L1gAT91XHK6PfhdivSJA83wEINvBKmAD0THIYD/9QwxNMGEnoHvu51OPGtYtRuAcWPbvIYDBDaw9rbgdIQABAiwHTdBsbHWQxALYVOc441e5ep3r7bTz5VIPFBWZD6uMAN58fst3ATqgBWM3n9pI3lL/eRgjgXDX/3H9YyP8OmPrBFnw22U+6mp9w3FxH0u1neb0AAOTTHbQcZ7zH2z8yH3hBb1tjh//cerq/JRv/SNAgAABAiRFe/B8mmmzFl3pOHtesfNc7LPnXxUECBAgQCAAz7MQd5hpS04hcw9btrB9O/X1Zhai4/DVQYAAAQIEAnCSBagwtnGjyfraBRB27OCrhgABAgQIBKBxMfYX7OoKoRBfTQQIECBAIACFPIpCAgQIECDA1wAbCBAgQIAAgQAECBAgQICvDxzXdQkQIECAAEEEECBAgAABvt4CMAz/Hn4EnEetBv48XMEvRuE/wjfAgTT4/+CXiAbHh5XDt+E/wG3fJ145i/N00dEB/xCOgQOvwL+GfnxhAv4L/AQ4UA9/HW7gIeYaSjTG4H/AX/XfrtZhGR1/9jr8G+/ufg5/CrYtp8W0w9+HIz7OtB/+BtyIcnGvwb+DIXyiCf4i1IIDu+EvQTP+8Dn8SagCBw7A34q+atl78Idhawxd0fFnb2CIo48n4R78IzgOIfhN8A4eVoluDsPfhTaWQBj+O7wRB3mFDHPyzlMdARTA8XnbRoCvyote2ozRru3TW0bXn7OVDTnGDBiEIWMGAaqssTqomD96PgGeSgHYDMfhmDF2E+Crwv7MU7+1u1/hV6R57L8BmIUhGJQlpMTrH1vnKTonwfKy/hEIQMo89R+HBlYHAX6RNcA96/5726eujP6Z1rJ/NkIE+7sE8DTA2kojK6oABEg6FTUJ8D2ioAb2LVjUKspxRuE7RCANfgJY8HOHR9HWRksLIyMYeCM/Bcd58dHfwSkfZ10MGzaQnExaGllZ5OVRUkJ6OkvAx+mSkqiuXnQBVwfcKAfogE95BC9DnlfKaCeeWCSlUg87gWi/9V9FDk4yyWmkbWZzHnkllGSQ4b96/KL9NG1dHvvLXq83d8Q//De/hdjAhhRSVMYssmwZ9TluDXCIgJrwxYv09GDZnwM5bKeRU4O3GLzIkJ1yrxazf7+vSm2Hz+K/LA+vQfaSvalpwXpCu2AvPvH5AlU/ANu9k0aetWqYqu9RBZdh1lsv8ciRGN5H0ELLda5PMRUhLNvZeGCpst6DT/BACN7w05tsQ4sDh6FqkTrxEIZ3iBcLSkSjJwC+NWAn1PjrgQvrJg0a/SyKePcuH3zA2bP09WF9f6qP8eIxji34XYxd3xMAkb5de7W01HTD2tonLGXn63QpKRw/rharQ/k9wAINeBnw1exgHH4ZD/ug3tdvF1bRz0QVAJFjAQWllG5lay21IsoVE4CxMaP07W/TBrNou7eNmnb27cM//Dc/fmZxAUgn3StjNdUqo/7pK+/rLk2258/z/e9z6xaQzSs55OS8BUgABhk6z+AdTCt87rnHVoZ1o1aqpwHx4zX/vSlSA3YZs4hBAw4Yg0XJTj2xqoiqt6nq4DYG7NmjvmQ0YDnoo+8MZz7iozHGcKzv/2NUVfkrq6cBKXDSR2+KXwMOweFodbKiGhCyR/clAJ4G7Nv3a+EkvOkJwPJ7/gh8NxVO+omau7v55BM+/ZT33+f69f3sF/Uf57gslVS/J/bOSlQ4jiHrTZsM4xcWUlHBjh20t3P4sFECixhOV1amHq2mrMPaHu3/AHfhLLy8zBN7GrBPtrzfelWUGjUCEDlmk11IYQUV29neSmsDDbvZvTICIPa3Nv05kNdOZrv5l38B8N/8SI0aAWxiU2QZdUEHOagPvjRAcKNqQDhMVxfXrvH22477LcP+8/7FqaEhpAGDP4TaExw6xPR0xI+XKlwbfE58eHW59XgFWmJhf4vPoB32w4Enn1Usbewyt3+I8c6Skti1SwH1soIA3cE73DnHuSaaqNpK1Td1UFW+77J2wAVojI0ClolDMr9nmYxjDNPTM/9rAv816yebeM9r0yLKlV+71MFTnGFRvzWx/y52ifetWacsBrySmsrJZ2jEPi7pYdadnQxPDoWHHgw8uHNn6NIldu826jMxYYLyykpiw717nDuHFYBXX0Unf8xptPW4rvAKqfDMwuWgw4SHGe6h5zM+u8hFucaddGrPNNP11BM/pLeytraa/1jz5s9t/5u//MtWDu7eVTNb2QLCYmWcYWaSySGGHvDgNrcvcUlNTp+N5whWA+IIBQzFW3Nz5tlfbQvm5rD7JQN4X0U9zAFfu1w4D6fgraGL2a1Q/zTO8tF9txqQn09f37htHsZqavAH3VO1KutZeJJiLFE4Ia062AiyN+Lo6yf87Y0CF8bg+/A9bbvP3L6t0Daf/M1s9i0AkXqxG08DcnJWUABcIjE5aXx/a5cuacBBYz7W5J0RKxoRSuHEY9H5LLMTTKgb3uNeCy0XJi9cuDA1NkZSkumMW7YYRz42NDdbATD27LOsf0RWUaQAWHK8z/1b3LrCFflTAwyI/eU1q3CVVBIPJJW2b/f2FhTUFBQU3N28+cW2EdvlV1AA/jUWi5RRbWCccbUBCdtNbkoALnBBCufiKiwooCCLrFg1wAXHY3lL8dq6WGFwBwcd7Z8LpZGbq/1kZrpPvj8R+DVP6knD8JayDvxN4M2nUQO2brUmAcC2EMmAfwGw1C8NGGVUdZt4AWgEquEgXjOI8TAL8PKyOPUiXOjn4ve5ffsG+Qrc5bTtZKdfAXB5FDvjLE/UMzjMw/P9z57dwhbP96+gIm52W0QDbOfvp1/N5TKX00l/l3dv3JC8qbUo7jRNLga8/o3Xf9j4w3O/d9YKgJSgrs5HRi4B8F1FkQIgxu+g4ypX88jToKqI8nM+zyW3lNI4BcBz7hzXKTpbVFhYWFBY2N46Yrt8vU0Fr1TpomiA2sBDHqoNiC+aadYde5/3FQrIUVILlNN0hCNAzBoglrcaQMGX7D8/CmFVQVvttOYyj/8D34KNUUvwU0uw/yngz3o/ego1wGPsy5eZ6uqy7cTE5kVF+ECk+++JSeJ7k38N8CkALy3Lnb42woXvIUfgwoUyeJ2GAxyQBqhV+xIAd+nzOCv7wJx1/K2Jayz1y/ffwQ7iQx7eyXIXErBYTFF/JpkiArGbQgG1Hfmm9+/HKADT4UOHwsNn7509t9cKgNmWlz/KE2ukAf6ryEMZZfvYV0JJMsnSy1/hV8SPqqVaaiUM5ZQTE2z61/ZtNcqSYv2vJHXLltlbt+xu2b59Kx1jLlZGuflim73stVGm6FpN8AY3lOdQAQ9z2MGJWQPk6Q8NGQ1gZ2QCAMv+ngB4wsBvW8j+wnbmUblECc8v9qPtC3loPSMjA08D5JB5iSI/AtBHn3X/de9ISkq8+y+ULvgUU92XEoEQlPpv5b294n3L/s70dMM8+6sj+5oH4OIH7gr2Sl2r5/5vmkr2Rn7qqEvAE9tppO1hj/wEebVgAk/roMWGsBGAQzXhGrksSgZYGx31X4PrEWo9ysaL9LexDVDv6qKrm258I3r6d7qCirLSstLSUsrKSE/3Rn0TOQEqREhcL9JXARULyhtQ6cQmAwzEms5ichLL8qNjjijeNUNAXgRgtQHL/makQqiALNkKZdQcnlo8ytueRxAOsxQWH/3fvBmf2LhRJuWwps+x139iuru74MCua9nfEfvfv6/OZdlfWxZDUvyPPMfbWK9e9Xz/pJHx4/PP/BziECsEJ/qTGp4bmEuuHfANh03XnZrCdWNYBVk/PFQ5PXxoemjIHWpxur1kwEsvrU4NrmoVRUACqWigmGJFAJYZRWLxp39TSVUbrUyqrKyooLJS1n/tWuyp4Dg6nDSghJJ88tUSFOuMMSYZ0Ic88lgOJp1JPV8AjAxaT38sN6fioWX/jZMIc3hDQGO5uQ9NEJCN85A9sBljbAKDTbGzz9ON0lJL3cbp7+4eV2vwkwqeYca6/7IY079paY/bSvamyH3Oajk4ov4vfX+amuTKeOyvRuZLANwETzK/fdvz/RW5HOc5z/1PJMElkyzplwGOYz5pK4sBc3Pls7OHDs2qgw/9kB+eOzfpJQMaGha5FvvJWfcaYAUyk0zAMuMEE/GnfyupEevLUrWxZgSAOFPBLrFAPV4ykEKKTQ/I5phjOfiYj1Wwaaaxw0nGdPez3zIs3wlv2f3Thv1FL5u+3D9LutlPlrVXPeb/Lcssp7PUHXXBecpSwRKAiCBAAuDD/R9hxKbyjJWXJ14ABMfPQPpncAT4uyvVxJ27d637bww89n/CQHpSwgclXDx0dhret+5/hxlvFe9b919cvBpnjdZdRhn1GC03V2Rto8aYsfcQEgBjp+dOawjISwZUV/vIq6xLDUgiydNI0aK1ONO/gHH/qdSW4mJsEFBU1N7ebb/fv183InEuyRRT8iJlgFUCeQb4xk1uypE5zemwE8aFIasBSi/knMppIrsJwYFb2P3P52h/D7mnsNgse9MW2BMA/3B83NGnNBU80dWl1rBkKthz/2NP/4ZChvTT08nI0DYeAXCffJMqoRFjBn8y/qM7wPi4N/Qv7qmhxhv9JzqS1oz9+/ocO+FLduuWEhTeYz+KXBL8Mqw73Omks4ceMBxdVhZ9VqY/Fi3hkNEAd2jYGW4eaPZmBsgkMLBOZcAlKqSOYcIywDKjLJ70ryyffOv22+yLPloNmO3utn/if1KYywqgjz4xs/EfQffKRjxEwwJu0W/VhC5zuRWoNt//BFyaYWCAb/3bgT/xb+eH0l7jt8HPwrXkpG+9ff3n3qbVHi3riFqJLIa75fhQ9acrCEhL8zRAMWHE86BRBKCffhsB3OWueDz29O+WLeYRwLw864usLPvHDh9hn8f+otM88jz2DxEiOpLWhv3FApb6pQHNzRIrb+Qnh5xEsv8009e4pkcbr3JVo9tqMHV11NaybVuctZKqHMYQQ8MMa3vnzj1PAF55RY607ZRrLwP+K+o+93vpteP+YqnNbM4gIy73f2rKsr/3mK/+ZU3tuL192v6VBCAxuM51NQDRh+5XCSU24SEB8P+gtpRjBGeERluZb4vluxj6Oer/wJVs9g1CNgafaj+zg/xsLrk5vParUAMO2Pno8bC/fw14jacAkQLgJY28WcHRHv9/5JebNrFcyHOTb/PwISUlsvXM/g4RuH7dsr/Zgsf+1rVaQgAShe97/2V01Dl/3rD/+fOVbqU38qMqX/E8V/OiHx1D/WOMPeCB3P8rXJEcFe0a0N0/etQ9cMCEgHFC9CENsAIgu3hxbD4ZoFOsmEvrOAv/sfLsP8poCy2ttHbQAeg2FVJYQAExYN6338AGkb01LDZt8oKA/lu34kwF+8ccc3ICNNv5Epf0AdjN7u1sl7MO+BeAYbKHaRyen4Y52MzQVWYmTmQ3vpnDkez5Yg7SK/ZXk9jGNu3UV1jHXC1jxw784LMovcG3Bnwf/h3rHcXFlsaNU97V9dALAti5k0cxy+yKzf4V+4sF4sCZhR+dqOR7xP9s398ki3K8vj6P/QmHRf2W/f1M109K4POIpxDeATtcdedO+tmzO365ft+Vfcdrjh8PHdcdW41o/xQWn8se8/2VzJRXe3fz3f4t/31nVW5t7WYNOh854qMb+utttdQOu8NDjhEAzTCKTAbU1BA/NmywtuAfK+37K6l0jnPNNPfQk056NdVibfnI8aV/t1r3P3J6uqjfaoDCWPV0/6ngW/jHLSwcptwpue0qoHx/OQFnOdtJp2RbnaeOuhpqeAIOEYkRGDZ6z4xl+Q6GPsZkgMnOOWRSvXDIphks+8szMF+hr+oheRmDM3/cB/v70IDfAUNPTSpYAoDnOkgAorn/upuP6MYawCOc95Zk/0b/L4EIPfFgHvt3dpZT7uV+8YEkN5E18w7eM9L1k5OlP/ZrS//vjoqKmrIDDcXP1pC1SmddhP1d3Jn8mfGS8f6S/l9X8sef3/Kz5eV527eW7K2sLDHNayMrBDsQZDv8xdGLX2qANaeoyCU+JCVZW/CPZaJ1wUdvprQEUo6/xsc0SiYfGdjP/j3sETmKuONJ/1rfX/EfEXDLyx2rATk5bW2D/lPBp/CJJpnXk6Y+nRrdPdqzuUfccZ3rYcLP8Zx9GGG5TyEPz5v7yFQvJ8fOASPHyxOoMWibRZbdn0zyMp4TrPTB/r41IPupSgWPRU8FP+7+W9FYI7yF8C6/B2NdLIpkaCQa/tGyBj489lcdpZHmsX8uSyQbEz4E1DAJDVjMzl7u77/8K/8nP/9sbe2OsbEcBV4vv2zpa4WxyW4Woo/M0czNPZu/0/7vfzG7qrSgYItchm3bTAqooYHSUlYCG9loNcBaa0dr5KviQqH4Dr4R1VtKCo6Dq//oH7IYm6zwhSxyYGSCiX7673HvBjfEj4DI8ShHrYMcT/pX9Gfcf7dCWx6F++UQkGRg9tKg/1TwW/jBFVlkZ5o+Pj32v8b6d/dn7c7amrRVYzIa/FHnOcIR23/8o3yIP/Kz/JHfjoVlf20rsM/5W7LFsr8sx9sfU1jmxBedPi1Qo/Y0oLkZr/1ECoCaqHX/Tfo3Pd1Qv/3BGqF/G40XshuzeQOcKLe3cqXmdnR0eLlfwGP/nez02aqSEvuOjO1wwAoAnZ189lnf6aMff+yKtTT8K3vmmWXViYsPnPTeZrcAM+GZ8e7x/u7+v0qHCO5W0ecmulSdDg+7L7xgnyCOv5/luXmHnP+XEG5qGvQSwipv/D1EJiGZtJ9ky8epBezvCYB9UyZQTrnIUe6/BEAOsnyNuNK/bq2NAJyFzdsGBtKAS5fsL/wIwCWWQGolJ89OnD0Lf5yWGnBdw8O9va//yut5bXn57flbDm+pKq6qoWYve2N5wGnMGM/A6ci5vk69a1g+MgKwQUAO3v5lt2oHi6+FBkQKgNeEIlPB9tHPx0f/U1PX9NVaDbDN/7BejHd5YsJjfzUrkb6X+/VB/WsjAPMaMDPjNjc7GzYwOcl5R93SCoD0+8CBlT/twlWM7J2ZYcamAZQHrqAio/vMpe6PGBiQPjm6moICrxm5xAW5lp4A/IAfnDvn2lGgrCx3717igS7Q2qT3afm4YTdR3pWv9lRCiXrVDnbI8dc/de3xpH8JUzlVaWcATC2kpU05Ng8crqgI3b1rf7QCqeCTwNG/T+VP2JPNzXH/PmfPnv+VN3e35RU+yKuZKX711YrMzHT84QqP4mELY2EeggOjdq4vMxPJ2VcMy98l++6jQ0AapND+MDlXsPfRmR/ZdnxNX/naaEDkjK6OjsdTwbPMLv78D6ypAMSrAQ4+4LH/zZsKWD32Fwv4jyWT1uolSeJ7KZi18atXpQFif5l2686uIKoiP0aBgkeRmvSgn/6OL74wQ85lZSYXLHpeof5ykIPeE0GfT34emRAuww+qowlAWhq5xtKQ6d+xcSO/BpKJgIPjLZZSRFE55ZIxWfyzf8veKhP7h6j8VfLsqRbQUqXVgP929+5fnvf5tGMluuURqARcabxu9Oxs//f/ykcfdYbDZGSQm4sCP584tXCAa+z/MmZpHoYwGeA/n625XpeQWUyBYX+1BLH/fXJOWSnFyczkxRc5ciSBb3pwYpv678ZxQie+VLAEAFF/ZCrYc/9VpY+8QWINsSfi0+rNvWhpWfS5zzLKolH/H4WTcGxtBGAhiebnu8eOORKAyUlZ7507VgNsHCD6FRLm64iPppnuoquFlg46uHXL+JxdXVYA4j+zbQKRCeEbD254yYDsg2T4Y+mFMKqZxsk0MJZGcnLs3MhPQXJkd/WWSyykMN75GV6/hcpTlR0YW8Bp3j+noZKcCrFyW9uYj1SwD9Qt+CSxHBigX6KfeuFCODfXlQDI6upiFoBBxn6A8Br8WhhE7P8uOfB7oQUL/gUMAl+Q8wV/BX4DBpw4sfR5nQT0yuiTwLW179tRT5HhD/aP9St7HGvxpIKHOzuxDaKnh8LChe6/hGK9zadfeQ3o7/fYX+SpgVnL/voQbbJYWZS0c9JaVo1o/tgxFcDGAe3t9z/7zAqA2ebkkLCXwdmHUoopzicf742gw8OsKDazOXJ22PXrPVlZTna2GQ560T9LLxCAxnTwLCb8yIKPK4yxMS9yT0/fdGnTJf7XJfgr0d94lo19q/0tZq/iIxUcSyNwa2sddSTZwMDMmTN6eWJeHlYDSkvdJd3mFh7F7Cxzc+wtc/dyEX72ND87Q1L5/W9x9k3K6ikDOrWfn/+56Q19yXkv0vYtyl6lzIEi7HsHEsH7MYQCqaTKD1AsaF8DJaEbYQR/GGXUvlYPML4KabIYHnaI1ACvQQwUJln3X1syM22YYMd/vuIa4LH/vXty+R957tNdXvtJWuOq2bHDCoC2WgT46tVBbyBIr88MhRLn6CSRFCJk3wpn3uY4NcXMjGxln0yqoMJqwHwyYMpmg7M2cIAno4HFsCstgv3T1uuAcET6t6L6Nx6vhE/haPS26UI3vA2VD7j6q+/4TAXHUM6GBgmAtZ6WlvPnDfvn5cmcZY+lVVYqp+/W1wODsssMNf3FHX90RzY/nkO6Pe0XMPiAgZ8lZ7I9548fzsZSFZnGbHyzHpFFlswmflRTffT10CO/Xp1lSfbXX+rv1doB+/yz3KA4nwf1mlPb/qS2lAWj/zYIXp8asPh8vr8JjbADn7h0ybK/PkibPfbXwyYxeA9JrCGsKtbVWQHQVhqg12d6CeHnn1+5E/mIVSeZnGJqllk7IdB7rH4FR4GEfezzgoAzs2e+TAYkZR3fmJ2UtDW2FMcfN2Zwfr0mBT0fnl8RTx4xT4BGd4pcDIqgUvYOxcX/6cGDWFLBPsrppqU5ERpw/XqfBMDash/Q2rbNLSmx76wffNc+BfS7c04eMY978k0MGGhm8Jr215U0lZhHgHgVcrHsb7brFKqPQgqLKMokU5zeQYc49za3a6ld8hVb+stOOu0b13UEbWOIACBybUe1o4e2Rd29m9K+fcHzP+sE7tJh1xGE/dC4vFzawuc+3QM11MQWOyatC208ciQyDohMCB88iB/E/3YO+zI40QAgSjb+WEYGq4PIV0Rc7XfOnevLygplp6RkQw5x4OC6fDCks9NL/xYW/tiXT3jyoyU+AuOKa9hJYQ8etPtIBcc+DulpwPe/f+GC6w0E7dq1vAZmW62dAqZt0nRado55BCgDbx0Ya527c3fnuHYSQA6W/Y2tX5RSWkGF+LWJJlH/da7rswj9CZmhbrqbaW6h5Ra3AP29jqDjxD8rWM1APNjd2Xm/M6Nze6e6UuRa8uub/Z0oO2U+IHr02H9gYAc7Gtyoz306+ELSmj8PZhlAyQArALLJTz+NfDBU/XDl4RAJ9f7LXL7JTRtO2teBUli4OnKHeCIyIXz7dkpWVkp2YSgbXoENy3lMo6+v78aNG8PDw+np6dXV1eXl5YnXAN/uv/eiB389R39q7dKltrawj1RwrKiv94KAyfOCHQgy26KiZfd0bwpYNiU5To6IHgMePsR+NTm+IXISgAs/aYMA1i+2YmbJ7WSn2Pw+9y9xSRJpl1ErppgFuMc9zRs/xzl1KzvrTb/VEXSc+CcE6L7Q1dVz/37Pg5zume715/4vl/1907XH/jduqF15T/6kkRb9NOsuAojCbSkpkQnhgcuXI+OAePy+URjDYizy7PaRhjHG1KBF/Re5eJ7zIhn7ICrV1fasK6kBEd5uCSURCeGSCxceZr/8zWzIgiO+b+GDBw/ef//9ixcv9vb2bt68ua6u7vnnn9+xY8eKNFJ3pdO/yckepUfJjrkLEtxmSrBRjNmbNyUiPlLBMY7MRSYDutrarAbIXnuNpKTlOXmieBsE5Ni5vk42Lp4wDAxg2V/asMG1Wm/Zn3TWL/LJ381u3QF1ljOcUU8R+08zrfoSs8uvzyIriSTtUZO2a2tLJM5yVhGDfX3IXvbWUmszyfFrABdm+nt7+76Eide96GA9oA/6wW580bKDkIdFHlFw44aX+6WPhv4Gy/7lpEP/cqg/L/Jj0jqaFJKVFRkHdLS0RMYBMcd2p7DotR9x8OBNBBNFXeWqmixiqcOHjZ+5Zw8FBauaEtrFLu8VER/wwbvvvv0uy8O1a9c+++yzd99999atWyUlJWNjWmEwd9u2bRs2bFh5jY4//bvNuv9ORobvJyTm14nk5k17GCsAK39DRCIRGtDcPOoNBB096l80I8d52GmJfj4CGBhw7H7r+8u8Kv6f8APWO5S76qZbbVUOmrwlyYA+y9NXx7HvzZYAqEPZl+tp9P8LvrjBDeAoRxUoiK10hJWaFZx0mf/TLxhQtRu7V81+HcDSTBec8s/+rzseLf9uFsPAgMf+Ysj6U/WG/ck6wFmM4eAT+z0BsCdLSkQO0L9nXFQUGQe0tNy17C97+eUY1+c5FYX9rQCMM25fdzPGGMXFZjTgyBHT6UUHq4/Ip0IVLLNMyP25d+/elStXXNeVBlRWVnZ3dw8NDUkGVly44hr/keG5/8tZ4q6sDPubvDx1dT+p4NjLtm2bupk1JaIiB4J27PAf0WPdfxsBWHtMGEofewuQg/CqyzpHGmmi8jBh+1nekl1Co4IKxQcZZFgBGGVUHpVuuT5vZrN9sdIJTmi7gQ3xu4ieBnzrSv/rL/ZP1U3zzXU2/nPKY39/zCz29xBNAK5f59Ilw/4dHaUvlx44ldfAhQNcWOaATz3sBxYKwNprQKTKe3GAthcu9NpRIJmmSsaAX9Vx/uuv8l+jv1J582YKSigtNRQgx//AASMAycmrUtRHXd1kkiMTwuo2y3x1eXIoFNLgj3IAjuOkpaWlpKQkRRuzSHwoEDFnJyfHSwAss615QUB/f+ypYH+IDALGmpqsBngy4Ace+yfNpFpPX8z42Fd7yLZfPXXvZiii6HmeTyVVF7+FLXLwdTc0fCrjUaiAGpGxL1ZqoEHKoZ+s7Auib9/u/N4/7fRe/WZUdX0g/G74Xf47Mj846PhayUPtpqvLyAB0vtv5n5EtF2VQv4o5gJ8kOlLs175RW2sjAEDbs7Dpoo0D5J2v6InF/qmpZGSYAaaSEtOMamp09kSVE/t4nI0DJplcboxcUVGxe/duufxdXV3y+pUD2Lp1q/TA/0X7v+I34J3lNgPrsae2aa9q2mZV/BOe46WCdV/27pVCt80fcmREqh3/bbGlihDljRutBugEOulduNBD7nmbDPDVFCzFpwzyDTZKtXRzI5ebzcrScZxULwLwU8UxNKm9slXUgFd5tZBCla6W2g46euiRB6PuOstsEklppKlo+oMKKrazXeOc9dRrPx7iK2J5OZbwf7IAeqGKhLv//nuTDzgyx+85XmXFkRSnF+L9phFiePW1wX+Dby8YBJYbPjtLWRnh8DSchXTY1GLiAPnoHuI6sRUA9Uv7Fhi7KHl0xHu66OPd6ifqP3nkSQPwC1tJB8bHx/Py8gYHBzdt2lRTU3No8cWMGuO7Yu9GGXzbZ/XY9G+drN26OKpd0bhPOJFhv7Iy0unJyVlohzZsJmBFb4uHwkITgKpJSAPgIuRC3gPJwMInkhsXFYDiQRqH2MCGUkojlmRS2VUCRkdzwLD/Rjb6rOJGloM9skSMBanRyv3vpLOX3hFG1HTnmFOhFB9kkSXlU/GrqdZn/Hcq35mA56tANgdbZVmJFQD/vckvFmpAY0LYX0iKfczX8fGqmhT7RUwQl8kdm54GhsDEAZAuC7M1tEInlgD4GOpZuXKGIcRiqKNuD3ummV5ms3GeffZZ8f7o6GhqaqrWM/B70bHfGVsGH9WT3M63LF1PeS6wz7bmLIwId+60LaFt3vaxas1v2zaZndIlnIdcKwNhqkJLnHPPoDEGsW9SIgJlZdafycE+/u+7ik8m3vf3AfkrMvuKw1FGIwUgk8xlTvdd3k3aUSWbFwD7IUFY+d6EI/NxjldZJSTFmPdzoqxZ5muvb1gPHYMuLw7AWGHsJ44Jq386+YyhmI5T8CWWe9Gh1a6ekCXqdl/xo++W0D9/0LtQ4eu2xBSVRejVEFyA3Hnb/ORaHYQhGCQaQiHL/jK/COEboTV7UUT8rcY/QhmQAAFIWG9yfNBpKHEC4KNfOqwJbs4LgLYvQQYB1i06wQpAzwq/Cd0bBYIKEoTbNgLAbF8iOgbnbeYJxbLsn008CLBVNi8Am3mK4bC2SCIKBqLs0MQW+aqrNiV4CVyeFwBtXybAukWbJWr/SST/3cGLLEYS1/cjBoJgH1GwlPsPDmRjLId4EGALVMGs2T71cGRreHLXZSGGhzl16l+fOsUPfkBjIydf4qcxcNjClhd44ZExPpenDgECBAgQIIno+N1YL7sX3vLcs+d4roqqOup4mhEgQIAAAZKe50mYeXaO++/yTzD2PLBzhhkXl6ccAQIECBAg6STR8QZfVQQIECBAgKTGryX7BwgQIECApEIWQxZfbQQIECBAgA18fRAgQIAAAQIBCBAgQIAAjuu6fF0RIECAAEEEECBAgAABAgE4DX8YtoDzqL0J/wfmeBxOAi0Z3lit06bAT8N/hB6w6IP/Dr8R8lboFPHDWV2Liln43/AmOFAMfxA+Wt8FibR9ROAm/At4A0IxVIfjw47An4cPeTJGMU3tG6vTSiC+s0cv62H4u9DG0rgH/wiOQwh+E7yDQQf8Q8zOVPi2dsZ0wcv7rcV34LdBJjjwCvxr6E/EiRfiV+G3RlzIv4GBZV9HGvx/8EtfxwhgH9SxSqiZt0KwyIc675xPJwKUwAEisAP2z9vKo3L+0AeIDS5rCZcAwasg1isKoc7YaiAUIQCRqIPOebtFvAjgJJZkUqBBtnBZ7G6M9UAbK4e0eeqXZQbsHyAQgJV3/2Wr6v7nL4iPIjVggqcJwVtvGxYVgE3zGtCj7QreVEv9+2EbMeBt1hJv8/VEgKRTiyQBuoiCN2EDHhpZPsYYe8CDAQZGGBlnfJrpOebsWijppGeRlU9+CSUppBCJXfPsv4dlYHCQe/fo62N0lKkpu4w6GRnk5FBczPz6Wamwc94WojxCA84yj+lp7t7lwQOGhpicZG6OlBQ2b6aoiIoKc4plYmJi4sqVK52dnYAW9tLqvlrikZhhr03FHx9nZoaNG0lPJztbpfa3eN6CRjELP8+jKIbniIbGlWZ/3cTubgYGzK1Uhc/O4jimzlVLKldBAaWlppgR2A4HrAAsLFU17P+Ennt0wydYqAXuY18VVfjDZ5/R3h55tv2k7OdHDpD6SB2cijqo+x0fqulsZGMaaZlk5pJbRJG2+ISPs8f2cvbDRNZRY5Sz3INPHo2x34AO+HTBzhiqy/vlApxqXDQDMMqjeBnyHm2qp3ycdeF5G72f+k8CjBGBVyA38nD+L4U0+AmWi8ZoAuBDA96MbyXPDjpuc1vb+9zvo2+YYQnAFFMurhWATWzKJruAgi1sUT/czvY8e5cyoQ5rfiGaaGri5k3TR0UcIyN4ApCZSV6eYX+7BPy2bZ77nxc99uict3tgjnzjBq2t3L8vShJ5GwGwa36XlFBdze7d1NezHHz00UenT5++desW6Iq2aY3fV199NVlXu1zcvs21a9y5Q1cX/f08fIgnALbU9vK2b/fJG1E0oPhJd/+tFaV+1YkKZSXNarkq3BMAK+fS3fJyVZy5oampQM489R+ATYuWav9+0zC6v0d3H3cQcsiROyL/I4Ol9fv6dT75hNOnwWAz7Of1AzKd3UdvXtCnfxPRYJdZ38xm9YUSSsopr6ZaXQN/8H92nzgEh4GlBMDTgAULJnoaELK/XX512V9GgXl3PUtowMsLCuBPebzz+hIAHxrwChYxiGCa/eNVEgAoaKEA4T/DKfjlK1d+mtghum+i6RrXbnGrjbYuunrpHWLoIQ8jBUAdT52wkEK18q1sraFmL3v3s3/Dvg1Y9i/BF+T1nz3LpUtcvWqoUDQtPz0cRhBNSwDkMJaViQTFLOn792sl9Zq0tBqiIt3TgIGBznPnXHtkEZNOZEnWdc2Rc3ONH7pzp9k/PMxzz+H4IUDp1E25/9KATz/91HXdI0eOpKWlVVZW7hZTLwuffsr581jl6+igt5exMSsAxlNWqcWSujx9NTjI4cPL5A1PA4qiLoDqrqjjL8a/fNnomYrT1kZnpxEAVWykAOhuqtqlu5WV7NhhpKKuTh88378yWqnS0owG9PTQ/V16vqeKOsIRudgi2ROcWDKwVBOQffyxaVy8YKjfHK2iwndVWozAdwkBTxIALzKWY1RJ5Q527GJXHXX6J9Hh/+z+cUi2vLN0wAVoXLDzIjTGdsGGhWMos8e7Ly/nV95ZLfv7/6kPDXgZYrwUUuHkquUA5EyJd/LzXRi31/IpXGmEv0BMuMGNc5xTf2mmWZ/vcMfFBeOPlmSaLrxhg7rz3OTkxMjIxI3hXv2NWrx8HIULnXT2VvYeqTuSU5fDPvxAPVLutOman3/OlSviffXqPLbJjXJwJsOTg+HBzj6J0TV5cfIra/r6tKR6zTPP5GRlER07oPP+/c4zZzrPnr1y/ryOnE+fOCevxjCJAoCRkXBn5/1b5+4byRkYMLSrL0SyPjA0NNTT09Pa2qqBIEBxwIMHDxQEsCycOcOHHxoNuHhR5ZKOKsYRcYhBwrPhgZGBeyP3RsSPMgnD5KRRhYYGVhDuijr+ukG6gypLc7PulDTVjtLkkptOUTLJc+5cOBweDY8O9KnJ3CAnx7j/7e1qAPUDAw1Hj1oBeBKqqmwcIJMzf5nLYn9r8j+IDsv+0ibD/rt26SDGDhwgJjxDCA4RBdNMjzE2wMBFLsrkG+1kp7yoBzw4xKE97CE+nCAEB7EIECSBjV+cnu7Kc7T4xBu1Owk1LBMi/dOcPsvZ85y/whUwbmh1tXGU9UHemyJmx5EAIOobHjbU1NlJa+v4lcEr7bT3JPUM7Rsarxs/UXeiKKWIJaEDXbggEpQGyBEupliO0ja2iQ0lKg7OBBN99N3l7k1uXuu4ltE9WDOSWTO1s2YOnoEcoqOjLuVM5+SZzq4znZfPydeUSm7dKrlUbRkBEF23tYkXxMMDYXGxPG59J4koLGQJqBJSNeKfm5vbpkMYaczLyMgIhUL4x9WrGpMWi6ngqcPhgzwjJ7GCCtGlBGCSSZW6lVZxXHNHs6nrpCSys20iZB2yv+6dkXDdx3PnTNFAZREpl1KaR56GCo0AMBcmPMyw+Fs39NbgrTH9fWdnaV9fw+how9TUgRMnjMg9GZ4A9PSEb96M1IBUUqPVtGV/bXWrLPXLvHP5xz/Bw1Y4zAK4uBKAUUb76e+kU87Tda530KHP2iNh0LcSH2LCP8JDNYEGBALgwfVIYdx3YiiK7y/2/5APz3BGPktKiukme/YYiamoMMSYlRUpAIZD1RM7OuQCq5uJBIaH976XVPcwvy5cVD0Nx6F86aHZ5mZ1Tf1YZKGlKw9zuJZafbYDu+OMq7urIykE0M7BqcGaj2pqZmuyZrOYhWcgn8XQCmfy8s7U1Z3u7Lw8OmoKsm+fGU2RkonqJQCSLvmsKtH0tLhrxFxJTY08cT8CUFFRUVtbK69fvA/oswZ/quSf+sTDh7bUosvk4fHneUmDGOIFKV8BBeJKyZ4cRnGHTSE29zWb2Ki8HOlY/AKwssM+IHdeKmrDOLWGTDIbaJCru4Md8n9VIt1KFcrFlbANMthFl1pXCy3yNm533G4YmW0IZzTMFubPbOQZSOFJSEmxGiAB0LZtpM3TgKMcZQH6+w31W/Z3XSz16wj6RdzjsVWLaoBETgLQQ494X15LFVUXuKBbqZ1TTDk4IUIS+xjP/lXTAJc4EQiAG/fK7d64v0Z+5Ptb9hczyiE7dIj6ehGcfGc5zosOhhg/uqXFKERZmXFS6+o+27dvCqZB2xNQzRPQ3m6GOES+IAY8znFpwGOrV4pKdrNbHUnxgcRAnWfnmZ3MgbVnoJBHcRPOYOx0Xd0XAwPY/PHBg6Sl4UF0KqqfnDQCJvUa6Ow0nCLC8IGsrKzjx4+npKTs0ngCKnjZgQMH8vPz8QkNOok0pT8PHhw4ceToTx194adeOL7juKjBo2SpnUjNxdV90e0Yk8aqru7dIxwmFFqp7uYQN/r7JWNK4UgDVJWie4mZRufrqded0l3bwAYehTRAA1vVVG9hyxd80TDccODDAxJ1ZmAWTkA60WDv3HwyoFtjaIpTvSCgggoegaV+mWoauQB28EdteoW4qoToGGBAXovKmE32x3wsJ0Y9S2GKzQ8rxo377KU83XBjcFMDJPlh/xg0oIkm9RSN/IhuRJTPPMPzz3P8uOHN6M83GsZXh6quFglqa/0z8eOleQHQVlYT9ckf9eGuLnXmMsrk/4rrDfsvgKhfpr40wog6uboQn8LsvD0LxczjmqV+zLbFcXjxRaamzIUthIjUDm3l5DBw9yHj4yau8QcFAaWlpcoEgI5QkJSUxGJ4CUZgeH4bBgOJzd27koHMUGZNeU1ded3h8sOW/SNvl8pbQ41IRJVzffa6odrBQYaHJVzrhf3t4I9Y9sIF6ZN8f7G/JFxbjXdvZCOLIYccfVtOeRFFknZJXcPDBj7ACoDZPrPExCxPAGQPW1psEKAWoq1CDebxxRd4o/9qQd7gT2I8VUVvz/CMtrqzs8w+5OE97ikakEbqOl/hlZU8e/xMunGjMTVja/oM9nOkrZbX7y6zUQYC4LKSuMtdEY1Ccjvu39DA0aNGA559Fj/YvNn88d69aiGeWnyxtACMjRkNEKNBFlnqKk92i0QWROJzmLPm5dibItj/duSwQTRs2IDjGLP/MeYT32PjWxtL/n0Jws9AI/wkC/GtRwVgRDY+PtzTM9LdPez25VVu31KxpaqialPq4hqrChFdGsETJiclZbJ1NM9LEYniGBGtRqhA5KoRPIVxZjRmKYj9v8E3pOi2dIThw3kB0PbHiQpLTPX1XjLg9uBtbyBI0uLNQ7DsLzO32Rv8yc9P5DiFwiCx/yijffR9l++qi0nOlR3ZwQ65MutolCQt7TGzyS5jkTvjQ/wDFgGS/LcJ//Wq+FTjlS202Ai7rs70lMOHn3D/fgFOYWwmYmBk4VCMjQN+Z9QMsDVwcKyxLJy3QYAnAB/Os387/jAwYARISmRELCMjSrDzWdRdWRD2zn6ECBzxBOAxDRgZGdb/a4eGS5iby922I3dLZV40bvZcL+ujichk8fa7/n6nt9dIr33eVKUuLIyBFu1Ylsn/tLTguqIz+xCwpWCfMOzvYQY+8CcAQmkpXjLgvfciB4JKKY188kffc9BQv7HduxM/Sq1qkVLZWTW3uHWDG9qqx/kRADdmVX8WTsJ/jUsA7AerAVYMVpf9Aw3wUVtJ7krXvtwTRQBttLXSap8qqqkxud9QKP6O0AZTRENyMtZgmOF++u9z33Pz/eISzDGPD+AMdPqfgyXuam/HDBAfKKe4WDzo8znfIfg+kXgeWCgAhRjzMA4jjA2/NjYyMibhkQBUVOSWluZg8TcfP9VDHk4wMckkQmam0af09Lie07961RFr68PICNPTRlykfKLNbdsk+8uTgYcPuXvXVF9rK6ARvJ3slMNr5Sp2nIZZ/MAKgLWRq1cjNeCLpg2W/U1kUl6+cPAnwaihRnlgOf6ifvUydTfpgW7uJjatrtf/i1CML4RCYnm1LjkE2noRgD6o1cnszkTkewMNcBP7LqAHPBDzdtHl4ooNKiqU8hUhxNwgre/RuHTTE6PpfNnZdtaxeogdw62nPoss/OMK4EUA3X6lqQ37CH5zM/aZdCN9VVX+J3oMwg+isL/w91gE6bLiseLiMZAJOZBrtsLNxSdj6+700WcnT8lVV3XFMjRsa+nCdxw7KdpOfJuask+XGopUNrunxwzklZUtQ07u36ezk9lZOfLyZ6uoqqaa+PEpvuA4kU8EtfS3lDglJW5JSU9J8+X9Nv0rXrPUb3NTa/WQShllqp9SSlVRI4yor+m2SrgWVpfL2mHLFtMM8vKorKSoyIu07E51De1cXfYPNMBdi5fByfUWxfTQY2eViWfUEhKB9HQ53WIfaY58ybOcVR5qjDGxntzJcsptLO8f/tlfjuH580YAPvmE9r5NPHfUPvFq6XUB2omCQRghxPIwNm9CrrHFIMdfLu0lLt3ghhxG9j7Pjh3qhDFyxFn45LxmHqRdvFg6c116l7LF8H9/P61X2l2RpSTh4UPpgVhSwuz3+Z++PpGvzVXYHGyCu4ZN7To2IfzDHyoTYC6jqaTpUvGlS8W9vXDMUL8r9lftRYGTkMH3IopUS/nkSwDU3dTpBhjwBGBdZHUOHTLhuJqBjaMsDh60O0UK2rmK7B9ogLtGbwNVixxmeIghQNQgXzM/P1FOiR1vamsTjwxPDv+AH8gzUpgsX1JOkwRAW9kKMsvEBGfPcu6c8f21vTFSzIsHOXaMo0YDSATGYHReAP4F/PNODFzuubgzzIj6Bxm8x70WWi5w4Vz6Ofaf4MgRt77eDGHHgHNwGj76YN/tM2/U91RWmvubkkI4bGjz+nVTIf3yltXP8/JMfasq/GBkhKEhmX2wJ5dcsdsadIr6evdLAQh3d6c2N1/pvVJyu6TlWklzc8mt6uptPgZ/7Cmc1WR/W0VZZMnsgKc63SijLMAo/jHqh/0zl9wROSQrDVg48UI748JF778B/Df0xAnAOOMPeSgDM9aXkWFdwISguhp10cFBpqfFx9MDZgL9da7beNnTgEoqNX66ne0ppBAHdBJNVzp92lCeIoC+gl28etD4OGrix4+TIERGAO4/ARdrEy7vzDI7yaRoVYNyrQWtP1c2VbLtxQ0KTXSFUqnYnsM7Lev8S8Mff+MbfV++d8fEeaEQdg6Ejfa+8x3mmpt1OxTvi1J9pfvGx42p4YAGiTPIkK1Jp7ADQZe7u/9qT89fLLxa8hdLejpKfmdGxuUDB4oPHNikb30kTtxVdnnSSZelkWZ7nGRexgK8hU/0wltLsv+PL8L3v41E4xTCp8Z8IGD/d+CNhArAFFOyaaZtKsja45iN9q/o2Bj53+gQr83MGMYpKKClBb1gp79fzq8sk0wJgMRAAqBguZZa+6IIYsXlyxoFwWrAVN1Bkb6I1ZgYNtHsPwfuc+A+YuFZfkECIPew5yd7/njJz/y85hpUVW2tqdm1b19qrCm4wT/J9RdKX3zx548de66hwYZ3jqe/jiPytPnwCSMI9++bf1dWsiTUaqyBhFmWSiprAbWc9v37L3V3X+rpyfje9y53Xu5r+mH6c0eL9+8p3r/3RFXVepicmkyyNUBxnrVY31PWC6c86o/O/hZrLgBv8QkyHwjY/9vQmNAIYI45F1fmPRdv7ckN8x0I80S8CMVY/DqeCHWKl14yA09lZXY4yNBQZyddXaNDQ4oGZEUUyf1vpbWbbgXOMb9NRQfW4T7/nKmtNXaqm5Gf0lISgctQHyEA7lEWgZM8s7G+OTROxif5P//fPy7cUlheXr4j27wy7TCHJYcsH8dzOFGrV51qVocq+/FhD2X7y80DUEZysXPNhoZ8CYDrMjdntmBbjYPDWiAc5vKdvZfvdF++3eP+i9Pf+M7xX5P8nd+4/3LxgWKZ96q49QM3usp8lyUQCocb//t3//t/58l4lnWDvfdgLzGgJRvOf53YPxUaEz0EZLuubMGj+UuEpu/AJFHwEhZ+BMAbyZU7KvffvvBAAiBXVBpgXzXXPWae9eukc5hhXV0aaTXUsHzI6ZLDOjaGEZvaWk6coKSEBGEL/Bv4hfk+7pzF/Qc8ihBzjeYKHz5kYKCv85/33bx59WJL1m52q/gT7sSLvBhDOuS4tSSx/yJZtpwcOwXCG9XxOx1arcZOTZAM6KZYYw3gTfjaf/v2qzv37Szt2l3a1TX5z85f/lOXi5OL7SRhtZm1XQXT8/ptNOBN71g2fiQEL74Nb4DD04BGYNeyNeAGtADnvzbs70BobXIAdtRH8fskk+Ewk5PGRAqP4BcWf8h4ZgV9j8xM9u0z9uCBqN+anHa7ZIr6dxtt6j/ppBdQUEGF/y4dmdCyNmWfdxb5JQ4FsAVKIAuGMXD+GO5dIlevEJdiJaq3l7t3uXqVz/OHT5/+ZIyxjc7GLLI8AfDPUn8b/jSkRp9Ua83qv67AmP/aDIUkGGHCajUyVhjOkkVtb7eve3O0VTOu3Vdb1VVV1rXP7epyytrM5ADXCMAxjvk/z2poQOS4v5quupuMGHDStqWXIuO4dS8Ay9SAG8YEtdwg67vqApBBhjV14NFRZCMjFBYuETeo9/+4HWZ0oRVOyTqVyH076hgo0/hDcbGxhgbDgurfN25QXi550OD9Pe5d5aodDlpsyliKTwFAAiBTH0woSqwGWAGwqFj4KWKhhJISQ83DwzQ1N+WRJ9nbyU4V3xc3RiCLlYd9YEBb0ZpajWyEEd25RK5PPDnpuf8mbDrqmvm++/btK+2alPegGjQPhjpqTMaqqFrD1fCHGLIP/9j5zzL1uDj4NB9eejqelqyO/OQPN75uz/w4aykA2WTbx/j66BscpL/fEO/27U96JreGmh/jx6aZjihJJ5wCGqOsWPcMfAhzy0zu2eUIjKvuugwN0dRk50b10rt45/AhAN80ApBiBCDRsOyv7XU/PCP2V4air4+bN2luxi7PqbDICoDFWg5rZGXJdGt0iQMM9NOvmyJ9In5ULSOrb+3OHSqprKfeWG09nRM2ghxvarKTA+w0hRChtaq0HnpUP6olQFqu7iYjBmz2LitzfT8xH389OgH7J0IA8sm3E3lucMOb3Tk9TXJyVA2opVZdfdadBYt7kWnik4u54idgBj5m+VBPOXIEXdm1axIAuVFyNhVQxyYAP5oCsnSsAKxRBJAO4376R34+RUXk5RmPsXfE0IccSSzWXAN0WZLnwkIJlCRZdKv4bJLJeJ8FKoJj+IFdz8eamN2yv2wTm9i3zyaQtL3Tf8dqgATgCEdYC6h+rHgPMgjoSuy8MOLG060B65/9Xdda5IsjEzrykwAB2MKWUkrLKVdMOjY+Zl/ucusWu3YtuHsRg44bXJs69tscn4FZjH0SG9fYZGVy8ty0GaWOkm/8Jk/EcyH4fwKwJv2gZGpqS2trSXv77YkJtmzh8OEl+od0yr6Ja2RkMkxYtvID6rFBXnVJCaWl0tXwVLiNNvtKwTrqiBmb4Rgc9TWhz77tRzY+zlHM4I9dVMfGjlYDjL3/vicA2lZQkXjVbKFFAZx915Z9rFndbTObE8CnT6cGOKwTqMPJ7LPOKdZWlv2dtReAJJKqqLIzreROacDh+nW2bjVdW5Tr3T2fIjYFISBKBGDt8zik2N6FZJKJASkQkq2RAPTJaS35vLWktVUacHt0VP6qhtDt9F4n2sCn5M6ag2ONdQKJUkUFlZWmrbS03OLWda5XU11GWQ45xIBkOGaNJeGt8+UN/lhjHlYArD28ccNbM0Cm9pNIsrVrn13jmiJsQKGzVMp7MjXQgPXL/mNjcrtQR52edhzvnXgJ8P0TKwCCqL+GGjkp8uO6u4euXDEdJTtbD8pbxfN7967DNTywCRqwINsGAfMacBED+xIICgt58mwd+8oB3YyZmSyyMsmUEQP2G+NvkGi0GqONLa1b5lq3XGjd8lFbaHY2LNd+505qa+3Ei532Eh+ba9Xba5eBQfGZWmA66awfVFfbl3koYOyb7WuiSSQr9n+e5/0MBPXTr5S+4kh57iqapX6OLi0Ara3e254XDP54cJxIDbg9dttLBhzmcMLIVn3KrrCts0vHxf672V1LrZRyxfnUBeep1wCH9YPOTrq76euzg7G5uYYSHWcF2d9ZLwKgTruHPTa/+h7vXbhAVpao3ziehw6p5N7lRi3NHbgG1+GPY0EFNBjzQN58HDBrjCti/+9/nxs32LaNhgYOHoy6TndLi6RC3diOn9qXasU0D2Cmvb19YmIiMzOzsrKSBOCKx/5mm9KaUt5aXjlWeYkqOYYqukom7RN7zePSYwua377N3btyQaiiWKW2mcP1gpISM1Bo5+5dvHiRi9lki/pd3EMcyiPvyWsQfc7nIkf54+OMP3/o+dCxkB/2n5gQ70cZ/Fm4ZoCnAWfORGaDFaastgY85KG8fumUyvgJn6hzqd0e5KCEai97iRMLeuS6hP9rdlhvUNtS51SAqe4HW7ao6chTTQj7J14ABLXLHnrkaavhfjb32enTYn9VgjxQ9XGRlGRgkcHkcNgubsiNeQGwOAAN8xaJIm8sSGhuviov7ld/1fRf+2rJ3bt1pse7+xdfmBc4NDXpfsgLVuxcSeVyOzDoDP1nzpy5fv366OhoXl7e3r17n3322VAoxKribY/9zVbQ9cv7U8glAVDJxFE5OSQlLfI2CsVhZ8+K5kzyW9CvVHDfk4ETFWvX1YleTSsZHlY7OM1pF1eE3kef/Nwqqh6TAX1rV/mX73+BC9IABXPJe5KTjiW9cOyFDcc2kOZz2pfigCiDP7DoQNBoW1tkMmC587AG/e3zFoWXwikj0kyziqk4wFstWRqwYjdxQY90wXn6RoQc1haTk6YBp6YaP99xTNz94IGhnXPnaG5Wy0lONrFuZSXl5cSCe95//XW9soiPCRMAReJqnRNMzDCzkY2fT37+3nszAwPcu4eyAhUVFBWZCCg9XWwlbRD1O6Oj9PS4nZ3GBTSZgx7uQi40RNgOHkepHQtqbp5tapprarqufizq15lU6XJ3y8p0G8zNcF3pj9l565a6u7hQ/6znmV3s2sGOGEZC5KF++OGHn376aV9fn96vMDQ0lJGRcfTo0UQIwAAexD52tE0E0dTf9OmnJuwZGzM+dEmJqV7XNf/s7JTeoVBMfzA4iHxGhWj6YTnlsJ5Gj9UmFCSqKagXue5Ua+v7vD/AwD3u3eCGdFrEJ4oX284xN8WUyLGXXpVd317hijIHodra5OP3ko51JR+9/2xu6ZKDP9b3jzL4swChUKQG3Jy66QmAiJjlIBf+DZF4AKcWvuNhmmm7AGQnndI55UX0T4m3TneMY9IAXe2qOteu+zRqwNphZoYf/AAF4xrgz8lRbxS1iZGMV2tpB7UwOcEarZUTHPvb8G7K/LD/tkdY/48kTADsQNCzPCslSCMtm+wmmi5fvqcuJ/UrLTXhT1YWaWlWACST6vWqKOf+fdrb70gnHM6bVd0p89z/aNVV0c+J5s2zzVs2NO9OY+zS6CX3gw90FJ1JsZa5DVYA5P7buWDygUdG1IU0enuAAzFE0PL6Ozo6rl279vHHH4OilrsKAvbs2bPqAnCehVAtiY366Zfc3mq9pVJK5kT3BQWmeq3wdXerBcr/MBUgV1rc0UDDPvatL/ffYts202dcl5QUNm8WN4vZW2lVrLOFLXnkKW7zBGCMMRVc5CgJnNK+/YfChw+fOXYs6fjx5NLSJDj2xKDcc/9VaQsGf6Jg61ZPA+TTRWaDl+uJ/y54BYv70V7cKQFQGSWB97kfJiz9s2M+dsFkbRPAqq7Lc0RFgHrohh6YA3Uw09N+4RfkfKn1SgAMtQ0MyCPTfhviHjnCgQPs3UuMOLUc9pexRgJg5wS8zMtZZBVSKGezhZY7I3cuXepQl7Prd4mhVEWua99YoIoyYrCJut1UbuMnRFViN7X4/RTzBDRR3VS9oWlD2qBRGnVIOUp32u7Q1mZOIKcyFDLnmJw0J5ieLqJoNwfFgHbB8RieNJ/9EtPT0xigNICGoLRnbm5uw4YNJBYiBXHBJJPS2s1svvbg2g8eTFy5Iv/CEz4bFBlJPsEucZxKLQ3QTWF9QmN3ipMzMkz0VlYmNRttbb0yqzJdCRGSe+4JwEMezjJLUpIR+9pa9Sr1rbEjR85UVCRDEiQT1TP3nvtsa/Mx+BNlIGikq8sOBFlTsMty8EOEsP1vNKSQoh4kr1/6V0WVAlaFrRJvfSZR+Aj+GYsjwE9Dj9UAWTjcHQ4PhsMY1xD7bivvOeeaGuNiyEuUZWURGyY/mfyE/4rsyQjBNpZE0mqHW/LXXuAF23ZrqGmjrZPOHnoGRwdHBcLqwA6OunQW6eVslounjiS1kMdnV4VdgqduQ7OxquYqT2nUSXQiOU0DEwMPJx5OM6ZTiOizqNHB1dt1JepCCgJiSv9KU7KLioqqq6vl9ff29ioDXFVVpT3+2L8i6mGNxQKVV+wvZlTp9Pkud/t6+oZ7xvqYBlTwYjbXU1RBhb6V/yjxe+LgT3L0L/x+k0x82LHDrltJVZX6jYIs7t+XiIVHR8MmPpgzXSs1m4wy+2dUVuondvkBeRZDcMYKgNl6pP6TkevP2+c+Cy6ZvdIV6aId/PH7mikJgER1drYFimktxoQCC11yHTw6Usz34SUeqk4jTbquhmqnHUgJ1Hp9phx+cqmT+8Ib8A4JgI8Ljv0YL63Sia0AeBowOSnr3TI59IIJMaen5REaLzQnh9JSBbcmOdfQIDGI4VLsdawwkuKcz+OfoZSotEPV4uVeeocYGmMsHCEAtqHLS5WHXkqpBEMfeDLC0GSMZnDRb1/kRSmHfc9BN92DDI4zPs20TqFOruNbhVCYv5vd8WUr6zTuLyWwSeD6+vq9foO6kyyGHPtFrFCJxBGqNI0U2xEhece24HIhLYOUUWYXQlBVxHCFaXDS308y4OSKzA1+8UW2bxdbm9xRdzeDg4yN2QEiEzmGQnak1SSUysrUvSJXH+2FM48LQKO3/ryoP+MSb16GSWzKSq6G/8UhpEm6GAUo1r+7DMVQQrNNCfibTZ7sfcl/X/zvbL+QfmeSmUuuuoMcKZaDRh8n94X/xh+AB98mBiT2gv/bon/34mqe2Hb7KasBU1M9h6b6qqZGRowAzMzgOEYAsrIM6VdWmoazlJfY6P864kdSTNM6HZYPB0caIJtgoo++YYbFUJ4AJJNsG7pIvIACfKJ53u7ioZJK2QgjVmZ0Ok8AdHzrSRE35PKnp6fX1taOj49v3rx5+/btehg05kaevRJ3N4ssBZeKbB7wwD5/ZV8XLAFQwfPIEzc5OLFdYVr0K3wbvhnxZcbKtlQxu2xykp4ehoYMeU9NiXaNAKSkGAHIzqagYNE38d2fjwN+z6MqlXSZH78MsjYsrEyyLBw7Znw51wWG4DKUQLEx18FZQktJ8SmREgA7rBQbTvo/uQ8UhyGEHyTggv0f4KWEnDgFymT7ptg3NTFhBGBiQgJg6D4UUlCKX3rgpP/riB9Jyx/XcYgP8vTlg8uIE90RArAA9hWJrCYKvwTLxhEfu+Kq3rhXLPkmj2Kjdvn7SYo+rd48YdkycRfO4CGEcJvQJZBdJk5ETuS/7gkA7MdDNMIMLVJ/LiuOkP+9sWNdXXAoyq6E1dSULC1Nhn/4KkICBMCHBjisHzTPj/+MEA0BAtwhAg/h8rxNsrKwA0GexZ5WC/AUY8oaTwmSWICwE37oPmQR5LF+cGPe979KgAB+cWne2llxDDyqAQQa8HXE9NMtABo+/piP+53+9d4Qm+YtQAD/eMYYf5UY4LJyyITfaiwGrMPTu+v8gr9hjP+QmLO+Zox/t77umH8BaKX1Ez65xCUceMg83k3szfeBN419dfC6Mf49FuuutjfCr5P5y4X9Rtk6LUckAgQIkMTzRMK+HP8aM/eBH8WC55/nq4YAAQIECATgJAuww9hXHAECBAgQCEBjwP5fTwQIECAQgEIeRSFfAwQIECBAgA18fRAgQIAAAQIBCBAgQIAAjuu6fE0QIECAAAGCCCBAgAABAmxwwL+9CP8Cenkczhrb47gOfwdOrNyRnZWwZ+DvQktMa8CdhN8G3yGR8FHyDfC6KRUXWZ9wlml74C/DVVYUw/Dv4UfAgZ3w5+AyfjAL/xveBAeK4Q/CR8SJhHVFZ40sOn4Rvg2pkAW/A74Hq3oTnAUWRAAJQ5UxKiGN9YJ0qJq3SHTzNOPgvB1gfcJleUgyxsaoHTpAAB9wWEsEApAKlZZt15Mm2UsK8Qh+BT6DMZ5CVEcIwFcFSdae6p4dIECQA6iytv6CEhYIgOxX4QtixzRcIrHIiWD/bNYz3PgFIAgFnnYE7n/sawLfvUtnJwMDTE7OL3D8IhRg0UjsePCAnh4GBzFrA4fNwe06fxkZ5ORQWEhx8XIHyz0UQyXfqWS0BO4nJVFezqFDJB7nztHRsWVmxggAWUW8jodGhFR4B9qhzWzZEykS34fXTj1arkz4BkLjp3AMA27BF3AV9rM0bt682dnZqcUstaJ9SkqKlrQsLS3Vcmb4QB99t7k9zTR47J/O1gYi8CyxYGBg4MGDB9pqfc3JyUmtsO84ji5Pa65lZWXl5+eXlJSkpqYSK9xovfLhQ9ra6O5mZITpaTW/jZmZSYWFSWVl5OX56OXuo60vGoYXDDnvhPqIhhDlALPw8zyKYniOaGhkRTDOeAcdPfQMMxwmPMdcCikZZOSRV0ppAQWsHFTrugNigqEhwwGCt4JuZSWx4tSiKYBJIpFFRGdsXKk74BA/1P7b29vVI9RP1R1c11Vf0LKDBQUF5eXl+pAoAdA9uXCBq1dpb6evj/FxXBdeiLfNSUhu3aK1lXv3zJ2XtEgAtNMKgPq5BCA31y70SlUVO3aoUcRw36vMj9+u4vz9lBTsgr0J1oDPPuOHP6S5uWp6upJDlXxzYdX9GFTCF/Ar0D6vAbshv8Xs5bVGODlftEz7G97CfEflfUos9dvtn+EJkNT2nD9//urVq2pbotqpqSm1Kq1mrBXtd+/effDgQTWvJ7UFht7n/c/5fJLJL6k/jYOv0mAJ//+n7jzAokizd38KUERUGhHMNJKlQR1QEAzj5GfdnHdvjk+8Oeecc8453/vf8E8zOzlgwKwgTZLUKCCSJEuy7s86Q03ZQFNd3Yzs2e9hR+jqrq4633ve857zfeU9AHR2dnZ0dPT09PT39w8NDY2Pj4cFAEIUj10jSvEMTgIVwUDiZc3N0tCAK0pfn4yN8aRJ3C9px46kvWVJB78vB0SHpLndv19vlYsYUGAFAIkUAFZGoD0R5hteEbuxEWSDNLRKa7d0szO8PlHVFFOfKgr081Q2nupaKqW7JA43orVVgkHp6IBhwgPBAA0Awk0G/QsLecI/JDA+AQCDac3a6O+8kvxjo9wBvLK5paWFedHX18c8nZmZefr0aXJyMkxoz549zNbCwkIeSM7UWOcAACeqrZXLl3l+NpPkwMCsb8onZobEaC0t3HPuPFOf3EL6+3cNDe3YOr5ly5OEhKeLiwmzsymTMztGMjIWuPPQdp70zXOUAwE5fNhDAGD4+QI7fmNmcZF/8T4aS74EI17i2nx46i9+kTPxdT0ZWWZfEcm2RpCxFAO6nzwJBIOBxgDPSV76VtvkV37guDnBYDC7qVoDAEKeVEkkA1tra2svX758584dkgC8B0KNb4G2oCo5weTk5Llz5yLA6025eUNufCQf9R0akYo3pOK0VKyg/f9TcWnQ7oGGhgYCEufT3d2Nuw8ODo6NjXFWdgBITU1NT0/fvXs3xCc3N7eoqCgQCBw7diyJlC7GJACvvnRJrl+H3+CHwE/ynJFIAEivStx/LOlAEtAvB4Wf8jvFfSoABBhrxIACRjSwZSPQbuLLum6uDd+/Ile40UEJkur1Su+IjCxsXkhgZj55mkb+Krt52mixFPdJX6VUEgkkBuPaX73KfQASuAMyPMzDuzeJyNbN83A/5j2TdXBQamokNzcuAcCOATu4kvG8A/ZNMGIl/nV1dbC0u3fvMinu37/PtJ2amiIDYLYyEfbt28csgK6RHFRVVREP1jMAcGe4P599tvVKQ7VUl0gJMZ/nU/NgcbiAeDDSbe45b3v3LmFud+e9nJyh/YWSeYpH5gPLPD1ZiHVPnkxNTEwND/c/fNjY82lGV1M+MEqugC9IZaVEowOAnn7xP0Pe8f3N5Jk6CCRfjunHhUL+iYN6GjyVfsXHwZ+CzC8NAP1TYkBjYyj4i1AwFDACRaap4o96GYGs6a4RDL7Z9DA7mOEfLCwkXQgwJIKRyN26cuXKZ599hj+dPXsWHkEM4HH2ZAP8CdgFcEkt33zzzRXVzFtyC1x4NnwdEH+gn0GiHgP1a71+/frt27fxdf6bDEBEoDl4OXx/06ZNeMLs7CyKUIdlTICCggL+48GDB8QJvH8nOaLnGMDH4YoXLsjFi5BP+GyOnPCJL3ExMXEocfPQ5qT6JGa7HAgLAK5SAXP9deD1QH+YPk+CuiAXrspVHgeSsDMBZlCxt2Lbtm0EAIgCYNTV1fWb3b8ZkhCBAWkINPD89GkwgPjLHQBjeoeShVl59IBY4sbU48edXV2dHzSTmIEZhoEigB7s8rEp62/e0D9N1jKc8eKFCxeYp0xJIJ6s9/DhwxB/rj/TFsIEeyM/YAogDZHBv/zyy0yWdQkAoC1zlLvEPDkhp8/JuSqpOiAHuOV7ZA/AKlEa8Z1kAkkETdxXX1+a11/8dYI8FJ9bC5IQAMi/QTcepQ+9hbGSG6ASDbe1DTd+GLqPUkSKCKc+fVpwB9cG7Opo7r6tcPwlBwBGjlRYiUgkRVOhxq9jcBB6/04wSABgsvEWX8B7p7wThLOSRDU2JWcX+/1fyc4ObNnCn/Miyiz4TX19PV711ltv4Tfw6O3btwOvfBDY+v777+NbBw4cYM5DMZY/Iwjo1yHgvg5e5tGQxBrxdRz9xo0bnICQAGVnHzp0CIKDJAXiEABgPYAOihDKFVQI6CdUEK6YBiqMnj59Gs3KcxqK+IMrgv5n5MxJOQmrhd8kSVKCJODhsF0ZEGHcjK725wwDxi8P+mOAPvreJblEGMANKisrcRJVnAEg0jKcp62tDWyCpRItgIIdsoOcYKtErUUgLdfXC5efGDDwJE1ePy0vvYRHKaVg8nODkIGCFy5ACgkKe/fKq6+uhvgcwvDpzw3aZZAqsLzIBh9iRmgMIBMlHQf9mRdQIv7JVCVF5vrDmbj++D+MLSUlBcZGohz/AIA0z9wAvHYtphdK4TE59oq8wvQQbwZ2K9uqq8t/dK3i7ALSXkmJoO2DzWhZy66ksbAA6Yf6kyrIvn0Pr1//qAEywG/xCHzBtQLAZFbw3fvwTj9wCiITWHCo9TbYi/Vx+wYSNQIxVWQtK1Y5qDuYbQaDBxuDp0c0BgSMHsM4b9QZ7e/A/Y2mpoL0YMlbhVkB/0wguzVQcTTy5YAywN1IKiHRpaWlJ0+eREsRy+AXo6Oj+ld+ArUEgDBZwEb/0fJDXwQAr8YHoUTh5ZcuXQLQOYGXXnqJrBbQAW7AdCKTHQDAenCHl5ElEACQjEhiSFwWFxeZFa+++irRIuokAHzp7sa3GIgYfBn4DYKGd1E7ciqw4aFfy/vN0oz6j8pHvb2mpgaWQFmIm4IKJyJccHyD688/4Z7IFOmSTkE4T/IAB4m68IMbCKGf6ru8dlzOnJFTp4Qqnc+n4iAlYOY4pcG7d+5kZwveWlYmVrjfYcO9/kfYPzci+m+x0L9GIhgaLPwMPnSVhEi4HmdOnTrFvNCiF65Ojs4sYAowX5gChAFuBEkwKtBx6prxDwBjY4RpaDu3mYnBnfaO/tTWrlyB/hMAApNXa15ByAFAuKPc4tUuoMmflLpnZxsZGQSJOaP2Yn1dIpkCoCVVVeLaVH5h9NsqEAHgy9J/NPzw0/V6sc4TJxr9/qA1JOjvv3U21P+X+jMzz2292PXhxe2Tt1871oM6GggEA4HsgC/bxzeMjF1oJvBoGER1dTUg6+z5ISTAMpjzgDKvIc1fLv3r6MhZjBn9cahh9XI+DofGfcGaEydOHDlypLiYfMaPry8rRY2TwRCWeDFsFIoEV6IGoA1C4FS08o85NGTQewYPQOSXg0BYmVlmo39cY0A4QBgb9Qm89Pzgr+3SToWfG0GVBVc57MiVuS8U4bngpAKU64nibeNtyMI90uMhAEAvoXfMD2ailnrJ7MU2KgAnT9IbwivkGSlJ7+/3DQ6mZ2auiPvOX255YehvrI6vNToiZ6QtpMLgO0AP9KNwotMyNezpwJVnnhIMIP7IQcxTAobdGUGjRLwDwPw8wM1IkjQaABji1ZCfSfaQ+ooeX0VLIthT1Tl0yKUjg1AmJC8hwZidfTr2/vXuWz40I5ICxKNoVaA73XdmFJePHVvXUrA2FzJSux849R8XtqDF4Kyst/mWfj+jhdH36wPTTxaebBrxf/X/+n/f+UBJIJAbQJET7E9bWcM5Wc2YsXgMKSSUAXKNr4SBLL7F7/krr6EUDL+2Gwxuy+3PA0DavS+kf8R3r4aLozXBH6n6cibKNMEayCY6g6xkgD54hDxFLky2CxUlBSYGaHHYdQ+rFmh/oHfHnJw00BlF0P13mjtJEx3z+KvWy2j1SIlXDFghw91I6I8NyzBNn/3Sj6qgsKLoH2Zcc03UYAyt460DMkDqMC7jaEHisMj5DzIv1x56yZD9VrPf8rmMFoT3M2u/970Jn28qMX16ekX0T97o60sU+k8xInVDoHASU1F4uLDa5oAEt5wMcVPgQ7we8sQkIi0mlYcelZeXxzkAgLg69BHBDPFmPT2ofcSAPW03Kt+Q6moivbb3msvlU9jHpExqmzkhJ1VSt2zeIt+Vvf9LTpwwR0eNhw8n79+9u0hOiEyB07guBX9Ow5/kNGsZYJ1LwfoRDP+sJh9a/nV3O65/Xd75OgvDHlx9cM8M3ssO3ssP9gz2VL5X/WQurfGdb83l7kkOFSQHJDlgZGa+LH/3vNVJVCarGIi5YBn+lGSZPG/oLfp7fRmvF81hjG6b/ps296du49VQoihFwHRQEkQEr8XLiQFucli4D3kxp0eIgv4wW4glIBGVA9cBAAPWfwUhEX5jzs8niLHJ3MSt2SSbvMOy2xgQIRK8eEPTp/ef2bctdZuyBFnFiAGEZFXeOIQDmbZ2AHATBvAvBjdBnY9B9V+WG4rQkyfcqbn09GfDp4i/WTaGmW5Wfp1aGjWRThxtDUBHgBUR/DkvL48kjIYIWckQS9vb20mImUQcwoE0UMQ/AECQGSgv3F0dnptaKflB/I4cmabMw0wPR39DpmRKe86gIRMyYQcAeo12Ze06mHUwtzY39+yWQMDs6jLa2tpbkA8RcJGQ4A5RqkDNodtfRi/QUpjJkeN8NEPcW0Aehx4He56VgIMI/v7g5pJgxZF/Har+Sdr75w//mZ82/u7Gnh4qAyjjhwKWpaSUyuoGs060zI4E8rwp6GMaBpR3QOts9B95yR8m/nirc0Jz8F1oC/o+Hkw1AqbjXsEEmHB0rQnDevgJY+INmQZMm5WE1edOtW8liDZ6DX1huO38IgHYL25tclIXNGk/Ow1rRnq6SbKa4plFRng1H4OQtbR+jc4INHKG12Bl6PB2rOvzNpyYz+dR5yFFJSeT5Qbiv/66ICFbA1DY+EZKhGwialVK/yWtRnZoRi0rc1YkNeRZ6BGzj0wXqYcMLMIs4AW8jESNNJqjOJY6meeW0KQVUzU+h9ybn1PSDy8Alz0S4bY2uokKEjoQrUFsfoah/1252yRNbdKGmDgog+AOVxCXIgBAK3Zn7vZn+r+dlVcsufn5eUxz0LQlFCJoUjchAHgpBWsAoEjL1FwH0+I5Y/+jTW7Lv04BaKsESx8Ge64GQ7Wjhcj87SUl5u7Ar3T+67kn21/5+mxGdnd20PDXhogBmaHp0tCuQCDHKJZVDT0HeQfKhrYDfSaFBH9REp0iO79HJlIhiNc7pf92//wX6G8dZXrCLz4CqoLLgt0iAs1hPcvhKMMwfk/OSwghfpAEKAMiEhAA1uzpvqQxQAyRK87X3BfGMvT/vtj2R9xpfvCc9nayHF0yrySK1cRGdrZZXCxHJX7GB+jqKcoYhAENAExYIIDMOBBAWI92VTSdPCTcrPWdmp7iTiEGyiqGSM1f8RYR4fUcCFWMKoLhe2A7Gg+1PZI5YibTmTJAhG1OGHPisP9o3aAdsqGM7imq6MqVBabE8oUaefmUtraq/bEVr6eW6JiGdMGhagLlSv9XM2QiXkMDKLOJAzmcy+g9AKyYqnHWDOThcWkFlBkeAwB5Db0WRVR64NzPIcYT40md1AExXLUWaenKGRwCkSnwJm27PD//s8eP/8Hwx29l7a7IOpSZmQdi7N2by9/5mtuu9U3SJwD9wTyXgjk33m49uz/5xKjKvx2gv47iYoJcoKenem8T05l2qZu5It9AmuaEzfNaGkj0Nx2a/kUg0JOT0yPCCKzOVdFPcBd8C6YAZYCJ27KJUmllEJg2VtIReNOwAsCOVlv6Z76a4t34CJgO3Q40+CMjoN5Q8oXLSJQG1nMghxMAlP7wtiQxsKdIAcAZA2yrlvsEgLA0Pl0rBe4DAKCv61so5XHbATVIrYZe4XLm5xvd3Y+HMqSa38QuOrQRnN8TNDQ+DNykv479E/juTBw6Z2iXgX/QIkHMwVwrUOzxkCVZ+2Rf/XQ9EjMXlsjKdV7WzzFHFOdWgjs7ZSfMhqSDMBAlIzD37OFkCY0ydGsIfBC+C58FQ1zJ5nTYJ/yWhf7GxtJ/gDI6aGullhUSRPsTFvTT2UScwyIEAPrcaMNjxa/KazT20Am9phzKy3ixdlVwLO8QHwnIJgf4kw74OI2ABACEGjhCVPs94Iv46O4pPIl5yy13UF1jQVedsPLw1q5bQ8hDh6sFsrRzJ/nhr8/OPhqt3TbcmPlgIDNzICMDVCQG5LJMlb/7UkcnuV58Z9QMXN9DKVg1ekgHczTu5V/rzVO7e9F/XJZ/BwB9xyBfOI+y87inpCQUCISoxdw0ZGmWQfZNf5rfH/DnBJpJEOzFw4zfvzpx1m4BBBN68PEw6AZ8n5+I8vwGMIVZK7bSdWrT/6dL3N8kYMRmeKoyHREhGhFsIDISvZH5cqwuFmM7I6U/vDnhTcLs8nMyBRUtqkHJ8sp01R+ePjXNZjfm5Yq5r3XIw78j8nfkxnFR+2rU7b50OOuaYpbNzDxNFrxs7y4EIJY1dkxOttUOwHGnquWpyMsxathBglgzPXUU1ZhfTE/YIAGAi0sCQlSAb+m8QGFhyrlFMkPohmJJFw3frPlQJ+EKQ9WdERpvofsQ6ZkMDNAB33Ill50holeyuEKkgGZhIeBvjHHmUDFQDxWLc47QZrNR9+Jj/cRluUwAYBwIjCn019S4EuQ038JEhDSdWUlThkS0HZbxSr0p2rsRtxrAbatb4m9zMzQGbN48MTdBAEAFii4AsJQMnv6MWi5yfy30N+1bSLsx0E8MuLi/de7Uq0Jn6JEjoAzXbHTT/ODszwZHBjPOTWZ9V1cATgisVBo5KZqSGeAsi8IYXIyoS8GzVilYB+x6nVb/zrkt/15zQL8pUinCOQUOHAicZ60WqP5z3RsIW/q/QMrj4PG/eZwY4GcnH+vA+ogBAOhHbIHpM2/pv6S/nrYz+j0QhSB0zGpmO3I8QScjJ+MD+UDp//Cxg6Loz8+Ybcwy+I6IUGOEvyjTidZAJaU/vAnozxvqO2sAiGCH5TDlpcfm4+mr09P/r29afuXvyPdJm8/8QW358QIrYC8NbnV1wp4poD/4xYImGtdIVBGACABM0JHe3k9bvv/00g8Sk4Ra81nPG/C2WyGNTwIxAwGcC8YIWyISkA3TV09UgEqjCIH+/InYQBBySWih8/R0UocbM8bqOuvo0+U6E1khBPZCMDIt3IYuXtaC0fqJZ9A+ywI6idqYtegBTJSnrG2qre2Q63+YWQ3UoGXBAiNXWTdWDDCETjnQX8fe4jGFfoZLejNjGTNR8MElk4jG7dCXsYSTA9XiXATOx9+IMBbiTs0Bt89GtIu/ECvhJhl7yVnA8eeajuulHoi5uv36XNUbdIbSG2TSmqmBQ9oeJT8aTBvMOhFW1lrAQ7SCpC2q+LonFYgAcGtdA4CWf13qP+9YCP5QRHFef+I8sp3/DMlfsfXoEoazVpxZSg+Q+HWs9RAryqeQBeQXujA//vhj6APeQyTAddDiWXLC6jBew01R9L+XPSsVZwX0p0hLDhKz8UEIx0pVtCahFMaDcSCH8yYEAN4TczMBAmaAln94zIx0Tsv/mxZoPy20nc9igPclzfS4ccmW0P/cORrYkTLIuZg7NLuQ4dO6MHbw4K/UvfMrn17/K7GUgq8wpkiphe06mCzwZ+YGkwG9iVQb+s8nfvwxpJrfA6OEfUiVuDYAnWofp0LzRfNo83sn3qPEgiptbwXB1UYwHPrNoZo9NUeMI2wNcEJOeG4QTz3SWtrfMjTUPjrKGu82vghuRngHDVZr8FuQBZPzM0THJlnRNn2Z+k+jNIL7Sv/T84cV+okBLlsUVVWbtUzIDi2LXADA7Fdi3BfeAVMVNJ57AcEj+BwGWAt1YkTntiQ1DKSGQq0miG2UfFl2SPm3sqzsW+Xl36qqylb01wBA7mAM0pVcmknYYIQRQIZ9AtFlnloKZuwduNOvZQAtBa9b+ZfTdxMAitB8lqA/37l7SNOPVY9ettlPkwRKmHr2c2YYkUMNBJmOe0ATCcXeDRRXQ09E+YH704nfk97zufizvRnp31yS/kVEsZvqMbxDU9RoDbmGT+Sn033FkzkPZ+bwnpibWUsWyAD0nTUFwTE89fwDvNBubXPjjeH+oD8xAGi2PxPuAxCr93MR5YP3xbP99gE51SosfKOTmozZmT/Rmwvl5yJQf/jgAzovCAP4YVQBAInsZXl5W8e2PR17Cu4X9Pyenv/15/8X9xqf0QCA0Py1P/u1Uz87lbsvt+RQyUtFL2WmeGk6IswgANxJuhM8Hmwba6v678H5U8Utl4Kic1tjABH0eaNVhGIhHaTK/b+9agD4rfJlGZVLcF8DQErOgEI/g5nv3uwePF1tZ7fhRTZ9GeZ8h3gHAM7JNBls+oFzMKLq/GBqkpySOjI1UlKIJnqYjBqjqMyd0jmSPnKm8Iyf/S6cDQCGAP3EgNHtg0A/VMaJNni4DoEv6IjS7HW5ui0EgwAQ9+5PO9UQF/amzf2X34ySZf9lW8FzCXGprP1hSOfnz59n6S8lPvt5AMgpugUQXVg2/V9ckv5RM1CEKRpT90NqJADQI0ShWHeQ3uT6+j+1jMPtHFZNPJkeq41MvKe+ebQrdgxHt763ttaeHu42VXRIDjcgn7orgOtAf4dVFslkg4yKjKCFiUcL7JYT5SylAR+Xb4dF2gH/APpJBZBeKUxDbqBSTCH35asENv5qaPC3tnaGQjQGfLJ3LzIdd5yrTaAl8frWz+5l75nwHxjLy5+QrinySoq3UT0UhRopoMl+c9r9kXUs6/T583I42fzjZut3Gp0xwNi/33webd+Rd9CiwaHvWKmCvIgAYJ8Sq6YvG58rP3LggUI/MSDaYpm5ZCpvqrkRQtXC3iF+AaC/H3/Cgchh90g5TQI+0yfRGPGDkchIFIZt4Dv7jLOdLNklvRzsAQajc65IBP15TVbWDK4bRv/RD1T8FxRD6rcMzJMKVN9dP60BgPDDu8VunJyu/g31sbWk+/4fuH9JPDYx2eYOOossExHdTscmZTb6Dx3dr7o/FeDLFy8i+KL8EjPQ2XEy+CCBRKMIC9Zd7s4fhviLSyaeTI8F9O135otEpa0YEeb319xvZy1gLLNE6+xAIUx81Y+tgPtQW9PI7cmO8yb8TAP9V6v1IzyT63FmpAKor2iwLgMA6Yzu/Y4LkNH4ExJICr9dVUVxyM4AyBrfffCACvCdW7eIdiYQQeg7exbty/1yM7plaP2g+Hct8dri6dO9lZUdZE6BObPYFBH2e3LGAJuczZgzU8YU3Si/Lr/+HVQJa7zA5h/muco+/Jzd2312SfeHA0RrSmWcbMYNlOvLMOc7eA4AvxK2K6DcE2p26JqJLS3lc0dLTehNPmpGtNU6hpmQwEk6+Rl3kUXgAP3BnQeBj7DandJ/hqJ/mPfyB7x6dMJqIdYKWJSmpWAGa3Sb7X7QkpJ4qv9zOfoRLuXRGnkx5gRNG/3bDs6w0T/oz5q9Omv7aPZdYNcR7U7jEPptWINOCAEOQOHXXnst1V34TF6y2SUDU7w924gDbdmUSgbvSSrjHf01CYjatMIl+CQnoWWuSGibBnzH4/n7Ebq9mRQ+n6bMzF8EWEiJyy1Muf80F7H3OxXt4vx8tqOhIERxiGAP8dcisG4H/awsfOUKz5YwqOcTwiFhfHfKOS4uIvVSbZghDMjJU7oHXB5y1s5RU6z/GWYbGYwjBmgtFcRgAB18mnaC4Lxfvn0kanMDoL/xDP1HM26cq0lT9C8t9fJkSHQbXYqvYo6aG+FITd9BLU4BQDuB6qequ7r2/OPiouwiSj0vyUsSpalEs7Bpk9ZriQHK/9hGHCLAYN4iKIc916b3am9/VT8L6o4sLRVxCuwMaMeEMh2vCx/s9vzm7puq2BAA4rn9Qxj93/DWYDR8Lv1vC9rSf6fV88f+tHQNsQfD0aNH6drUAEDnKFGBvTxVDmInH3FhduEX4NbWN4rS3nYz51i79Y33xFwGIcxYc9uG3xT5b66anLXIRRiSXds4DyGYRZZID0lM9ofWgFjNidFb9fx0uLoCtKk2NenzP3b5fOzNp7tRhu2xQTxgiwJ4gPZ0QQv41kxDMgB90J4R8euT9wclqN0fQqoE8a+qAuLxjDzZKXqsdXQb7+yIAXwEgAApZN8hPpxGcJDhhdj/UwATOgimWSuzWPCdc0feq64u51JRxPS234dWfeExWhDGlNlENl6jLwb3ORxjbnoOAIOyzHa2TX83UJj1s8yc/J1l/T7f6e3RVvt1JwmGtmsi3cAS7I5sfurOBM7yHbWBdl9799/s7vvzfZVb9A2cG+bpcyQTpSQXDHcW2j2Wgh8trQomsNCmGoMhuWoysX9ws7P8u/HtvnHf7vpfWJL+mevt778P0NP0TXsoWAAiAAd4GwuvSNq4a2+//bZuxEYxwE1Z2GcZ7ZsQSbIHAgn/weESpeH6HGgvftF+UE7AO/ovjwG/A9FhzeYNLXKJTmISHIbnz459eyElkzqUIqoG69J7cV0q2nwrvaHQ/xVvDYkg2zfRDkQqwKPc5ltbaeekMcnNk1aZaez4gpRPXEIp50BKJrb6SoMW9N8OA/eIRgZmmFYM6N3d22/2PzQe5u6xE60XYD+VBX5oP9JY0tgf2pFc5hs45puoyOCa53jb72Prktmdctia/RS8EmMuaJVeD/ccAL6//OEk35bxhl9rvrD7g86yTvg6SS5JTrTNegxokb3zH/+yF53zNyYwnkRzuq4+vT90/3rf9YbdDQNpA3/23LmG+U+ZY0wwEgncGHxCeKTd4t7WUpQ2ipPiUJ+9l4KXdJtYA4C+ibP8u+FNd2Gy0X/wyF5t+uQn/A6JnyUC+CJ7NoAINs0HcFFg6CNiTzdWonP7CAlu8NdejcyiM9aa6v4nWoeIdkc5jqUorRVp3hP/WbMUYUSLrylrirCi2qZz50SJ0WKPAZwTA7MZtDsxCyWLPEA7BWgK4KbLKkYMQAUiHeSycwe13sD0JsJLRCMDIIen1wBMEMR9GlUZDkNntpMA7N7t2/oVeBRG15n+UFZoNGGY5J+ZytEvxJLkB99RCJb5toW2f3az9v7Y2AEQSpU3T4nJdst0Bo1bxuxzs6SGV+pWvjssiyUA/CAM/fk3Wny6pD8eeGyMf8A5QrdNdJJodp3mcuAszPuhXl0TZvAeglBpZmQZzxad3+m6A4gAKExpJvPDRw/v9t29+qevHk87Xu579IFFqalLkWVC9ZqbrYeJtefKuQrKtmF6W6ylYOgPKRxkJMbyb7ej/LthzVhhr//WA1NSUaP0HwpJjxAUm/BMvg/C7nt+wlG6100jgHKIvMtl6EAG7wO4oPsRV4guNJXTYqQVaffGUQQeDtczIQvhbb2jv9d6gAK+Bi8YCqGAEe0OPHHeg1hXxjAwe8mMC9MMHTfWhzCDJpEZJS+wZTftyoAjRgYHJF8aeOCByAGybR9vsSJcEgM0AOjPe5A+w2gxjHvG044z7F/CXkcm8xZAekH2/STIsfV1PjM/mzamD7bf4IubwDfn9NprK5YmjIi3Trd/wEREM2PmnUQ0XsDLMBFhhuq6yFgCgJM98Q/9uYtGHWA6Y2brMJMN/Obz+Kri1kjVaEiAUfTfSOnrmyHLpGeMOcOic1aQs4Cwd6yXh3sQyoAYitrDI8NdfV1Vf7mqMquyfN+tu3dyttdCMBGCUFpBV6kfKR07e5w2OPJNz1vSh5eC5/zNdj9oIBDr3p/zzvLvi4f4yMY6jM8DQOpde8Mfsmvn6kQt0oQ9dcveM05XYPFKl837MEfd7VY3n9A93UBw90/14hCUBzYB1QDA4bwh2xV4vQzeYwAAqyNcD4pg9SJH1w39nVgs0bXJaS7DMJKStKXEbQ+iHquHRzTUKGQTRqTsxBSsgP+J2GHAMG7+E8NoNtJ7ftj5la88IvMnOYk1fHu3VxQxq2WUSEYNiKjWduOGQTzT3TNZCBKlMZU0MyaLBdl1yyzYfQRSr/tfkUZrxsaxsLH4PxRe90ln4NzKLCJHs+Ucib40SNr4Pn93dwsLU1DwaZKGObGCfMgYwuOa+5oB/fYt7alm6r7ZfW/JWywxr86vzi2bnx0b+6R5562PR5INYzotbRLFn2ZquD89A3iBw8zYVCBKwbEHAI0BlH9/WfSfB/LApv/z9oY/kHFH274uLUmwbMWeTu3FxMSdIStrIREWjwezoT/uC3mhwOCmh4GN5NiHgNoj8UNrkmQPvKdmAPEzV26OJgrGErk4cZ5RoBXhSCh0n4RLYrV+MqmISo6KrZp/qy7hLjjzfRizU8+M6jricoT1qLp3rAZ+LX6s2ZVJaQIkIWLaCQeXa7VrRQz4PAB0mfJfpel33mgy9h858kdLSy+WlJzZv39XnKK9d3KAOsIzRLnlOvqvX9cAwPDQUaKZMeksxS19NgAThNqbrGTspmVLr0QODtQnacc/AAD5OogCWlyKaopggCEkjXl/71ZLayuh22C3NzyNbafQfNKN9CIpGpXRxSeLcBWqpvyeDUkO5B6Q0wvMLbR+hC6YAhcXBUG3ujVJLOJhbGSoYL3vUX1fLKVgkhTrcMq/GlQ2fvkX8mKj/6Oy3WI1ffLT+YgYDM4+bxnNBmGL19W0/9L9cjA4DuUE/BvfpbmIdlJoDu9ALwBVx8hOTMbAU8D0WWBEAqRPniLJEwV0Q+n1sciNLaArGEsuypycpSGU/1t14dWEhf43iFq8WQxdQLzJG6s/BUub5DgNjOSbM3GHC6pfc3vAZXilPkGaOC0rGeRUNwSFrsIF+P5uIg3hhZ3FfOKj+DeBZsh5hkLUc+CIK8aAQv7XLmadKRflo2Kzt69j/1uXZo8aw2XGsJxhWVKM0B97DKCCUWlWThjPAsBHEx9NEgNAfx0Q32hMHwBAOoskzqJLElz6L4gHK84I2A95MNqp7qmuGziuwzOB24XFQRQJAQvtLWNIlEZ+Ak8Dx/s6O4PBJi4LOwzW1Jgiggp00Dz4wHhADkUqgH/ohrT2w4BIHUh1IBsEAIKBGdmbvSYBCtl9SxoOAcBz9ydv9ctC/230b9k/IRVvKP136sVoMkAz3TUwEa0HhEmQ6P4AAeKj1qDEtYHaYAdvSB8nGQC9pKQRMEpwBzrPTNBNKJ0t/+QKnAZTgl2Mrl27xgQgZtCLwt4VNKeiIMkLMtU4YSZArjbSkOQCu+FxA8J75Zpc75KbY9IWw0KwW1RgIZ+rPFywrY0gSZMctwdEEa2WutTW+A68GBwJhQAg1v3BK5EmwKDlGzqRhIFTxGNuDQjEPOVwN+uy9speHmLKBEF7RMujeZQryIH8DGOTBBnaUgtpBgVV6669XzXzgwu5/+8/XTP+lGH4cA7jjJxh97oXvh9cQAKaAQBin/R9Is4YwHBtTDQSWfyfi4+Ta2bMtGJ7LmcMgCdx8TUJRgjlNQRplmRybLwDwN8WWrX4VgzKHdrPo84UtUHQQiG4yZ33B3btGuay8Jik8nJutJASHjJXbY2mriKMNTL0vZaqesz6+SPPCwLqQ45VwdF8Te6+ij+p3f1+qdz47f+6fdXnAWBrvS39MwmdLAxJEWGR1BK6TbKJX0I0gFqFAAgILB4ajgijj7AQ10a/M23mIL5mFfg6O9NRzoJUKu6QJRB+yCrIEYEYSkTEBv4KLQL6ORmAiYnBgySJAfo0sRdl+lxqfIilSybgSys9lwi2FAhoumzofhH8+erVgrq6vKPp8kdF/qLnuD0uvi6ehiEJSc4GSkV/lnHRyM85aMc+0Ox+SxqwGFlVGzofdnVx07lNKDxAEveXkg8hWTeDwxNAH/YKBaf4phA1QTbks1wYnA9er3uOjnC50tO5SswgzpZACr8E4QwIH+GUi9bWBtel889vmmdPs9I2+c+IlBdf1eqBxgB0GHkh5hCuWCOlOyUzbrTcsNGfgnCUMHlY55Q+7Z0pwDWHe5EW6AJMTbwIvXAgbhAcCI2orKyMlJpEPH4BwPhiva4O6toAsQ7xYNxaxKzBwenHj69e/TQ5ecZq5TaIAVGeNmcD0hpEItyVE7WhX3/GWgq2+0HxaQ+rfxec5d+Na8w9m/7P2crPsmQfRZ6cVFvClWvoQwVwRBy0wTJcEIAgCY2Wg9MOxMIC/BvHJYGot4yUlk/kT7g7EK8BACUavwd3ECXQPTVZZuNScJ+2VGKAvEgjIwX6AEBoN5HM2hgafRMIA7yYLIbBf5PFsoDl4O3bVYf+4EzVr0iVeLbUf7d36wc7t9bW8rZ8JOm1gqagqPBP+DIxABWorIyBEs3Jud+OALenDZQ5xhsSlbnyJGpkXSRkCkb8hjhNAOaX7A6yyOytrsZ5CEUuV+SQ4h+RIyzpAjHZRGGcrj5yI65PMIj6JLwhzVTUBhDTSKc6OhKbm8tmisrN8sqWypOSeNRqb73SecUZA9CUXmwMSDQTK40vigGtziTgxIloWibTcWwyYwgWrTFkxvoEPZIw8gPmHf8kFSbxYrJwL5QAIZwyQ2PtbQ1H/7AAYH8fzwat5p1mZgYWFmprL8/OTo2PE+YNzpzchaUeLjaWNjo7mVZMJWBIvvY1gMLGfYaqwDGWgm8ol/cWAKD/G1//IZmz0X+gNJPZq2M1SoL/Ab64IyQd5yMtoPALK0GQoRKFC+KyAU+Vc1RL0B9qCd8nfsDuec+gZfg6/UV2ALD3edZFZ+S8iEh8LmkEUUpesAGzkGboDcBFf+oD+fBDwItzJWPGswE4HD2vs6OqqqOm5jevVKVuzdk67bl1rXzLlpFDWz6+I2+/ja8BmsQb8JrJBe4zN/gp3A4aUYjrTLqoLDeXA4FgggqxpK21lTIA4ZYbRCeYbgbHrad4g/pHaGGa8CnEgKhgjg0FEJbpCIJ7sSS4E47PxOZyUUhAC+LTuWIjI0n9/bnzh4rkdTSWo3K0oriiQBZ1fQM/67rqnDEAZvpiYwBB6IuCsDnR54wB0bQ449t4Oy0VUCsVgki1ycDQggjA/IlJx8UnJED88X8mIJtxScyWtGIhhSitA0mEEWPnLY7C3YVoDGzZ8uGNm0NDffgqfUFweYpAJAmkg3yIrf2aJvECx4YNwEt0mS0KJ06e+MYbZd3dxxwBID0+peDB+j5V863ClNvyr3XI/qHkjVX+Pb6G9N8sqSCFov9q6i28D4qBUIMaoNDM/Mc7QW1SgTfffBP2gRSDO4onI6vgTYjkEH94jVaGSS/QfBAfKAzg9KQCYBAMCJWJD0WGQnSC8uS547ZrTb6t+pIYDK0MAMRXyZPxYUoAQ2MXL5JAoc/gzZmbZgoKZo9YRZa8k6l3A6mpRup8pBrApgh/SClJSZlISZk7LXBn+D5ArKAJ8hB/EKTYiRo+zgkx3ZhUURrH6pNk8H/QaJ5Hh6L5MFFnZ5mQlIj4UihFZHDMW16gnyVRhmEgmywZ9YZ6AAuDe6eRg0ZmpEMfA47WnCEH91p0ijUBPMOHdIYXS7HYAYAzvPx02pBLdgwAa11dyfj/jbkzRxQ4aBzUGABgfjT20awzBnC5XBtzCvQnLQb3cXUSX2YE3AsyBGFirjElEYUgZ+g/xADmZjwCgLEyW6T8SxFYtmy3K8DeDe85exb3IpBM79p1ubEx9DZ9QRPop4R/ZpHPp08EIkbQg0ifCZOK+AMbYAUCzAZV0Oicyp8rKio0SkOho8eOHU1JORz/UrAOJkA03Z8brvz7fVluQQla6J96U76pHTnAUmSYwOFeffVVNBkAF3TW7aABZeCY30BDQGSJwfB1Crm8lf1cYkQGNB/kZupdBADyAD6O+UDyQQZA3kAS4H7Xwx9EFFT07zEbJA+n1dYP+4HAnPwYhIYaJ27BM/0RQYdytrO25k1508Mppyz9YUfVjq1JlcwWtDD4BxSJqQIEM610Tx4+DMWVYOD9ywBYxFe+CeIM/Au5yQ4AiP6EB3xGnzbjNfZXSRUFYfZ+YP70Sz+Nq1QcNQBANvVRw6wW4gWsQ3LmpNp1ynfkfC6JGAxp0BhA5HB587/n0WlSIjsMtQ3QH8mEMzHvm3J9XnZc12JAVCtMaWxDdoMVkYEB/VB+uL8GACYCUw9K5L3w674LiCUbOrQBlNsf++aTgmhLroeH+f29bQW9XV07Pr6/ZyvawmJaGt4VFgDwPQIAOXTWwD5aFLLxSwhIN32EZWWhlPRiiY8p+tOBGuoOTSmmM4WWlYLTlnXDaQDY1j2z8QMAa/puytab8o2bIrP2Rh0u9tLA4eDp6Dykn/YDYfR5AArEsRsEv9wybS4izDgDAHIQfq+V4XjEQbWt+sd4mT4Ckp9kj3gs3TG4Mf5MkQCQpMaJY2dJyaQxSc4V7Smn2L81hMa5PRXlzCCQWnQ3ZuYoM4uLo08B4yRivC8qXrNTG6k3X4ZJyGzUAAALJPbwQbwmNqOHksHmbloSmLW8kgDAJjHwfTJpNCLBzHBdkgvNWWk2cFHE0CEDZ8QgeKx587/n0WlS3DgMBWF+UucwOe8gV5JhEgbIzKLrLrMMjk/7A2k304HMWyVTpp69f+L6BgD28GeA/eAxg0xT4mFkjjAlBEeyZdBzvLd3fGCgDaIxOA7k85Bvg++akLCgK1MAqcJ0OZWp/RZgLLwjdOBAt0hIJF4BgHUsLEeAlfjmfXPdczD6FUvB31+5+zN988I3WdXMO2yg8u/zvPwJ4o/sA/oZD8WL7bdM1tkyLZP4WZmHv3g1XJWF7gzEGBgzIAxa4sI2hrHS5ZysCQTfDJ+G/GrF9iMGsxLxRwMAHBOAjqPB+ZinjPU0UiKGRGWkIAw1RwxgnCGtW/1KYl8XzP0diHwTVsbMk3JSbLtOAFga5RKtxbTDT+wBgEQGBYsCy0Pdy406V7wMtoL4EAgg65BmwvAJ6bgyAYA1R8R26BPezOzhlTAOnET7lPXG94O91hiAn0p8jOXHzM9SKV0ILQjhpbtv7QBA8hqqku4qYiTpqq5f35h2c2k0/X/2zjOuqXTb/98tVQIiIFEIwtBU0BksyH/G+Yin934O8++99zf/3st9dc+r++b23u89vdw+fYQpeKyoY4NANIAh5BAgkFD2/V122CcaxBDAwjzfWbMNO/t5kuDH9XvWWjvPYtMxyBXLHgX6Z6LA+YONnaYBRY/rfVjpWZR7NSCrnM1jEwA1Y1eeTq7t2vDL9Pdz+TKlpdTVablBeTnrR/5dsbFMsUUkokhTAkC6AJSWpi9tBsEJAnazYeityAiBf8kCsJdUPkEKQ+D/BH4I84RzJUUAth4Gw+K9GvAJniTG79UA79MjADXUNNHUSmuQ4JWzZykqkptWlC4BoLGRj32MjUITao0vy5jBZQ04DPlsNP5ledn7kGtkTzgjKd5/FsOjx2bzMSzA6SdTAIQ/RQM+yxOIZWOzEnL9r/LqaU6f5ez1kusTjfXJL+996Ut0dbl7ntiPY0OOF+GL8CVo3vA9ofI09bKVsAJR+B58d+m48Ij8wzeWrAS64FMYDAbDZkYAoprqk5wspLCKqtbJ1tD5UIzY4qkEtv0kyKoTBDSz0cylLPCfXTVEWOCR0YXsUWEwGIwAiDrqlJ1ppDFAIEx4hhkbmyeAO8uJoBBUPuKY+7kl+59sZQwGgxEA4cFzhCPOd7hXEQCbrYXBYDAYAXAppljGVsFgMBgM2/jgYDAYDAYjAAaDwWDIxSZDDAaDwWAiAIPBYDAYAbAet63CJPwqfCq7eTIZ8+mlF5jkoSzA78NXV3659b6P1cf/BfwrqMrw6lvw09Cx2kUrzlMN/xpezuqtr8o34SXIgb8J3yYD3oP/CM9k/OqF8HfhBxgMRgAMW26PgOqkZUb5sqViZf0q62cxy9+WwWAwAmDwyTJ3zWVQDhWQv5kyk6m+2EkzGAybKgAG60l8YYt1sxOqwQeVWQQBmeFdfomdbCyLj14ADAbzRTD1Zb148eKdO3cANahUJ271ZmIjGGd8lFEdo0RnmZ1n3sLKI6+IolJKnW2oCylkjXzjgUWAP035qLkNNLTRth6nfP48AwPMz+PCp6AEhy4E75DOAvQuT23VUbeHPcCtW9y+rYYLJBLk51Nejnpt1dbauCwu6iKGh3UR8bjT/cNp/7T6FqrfIYXqS1TfxAchnDbWxzi2gx0P+IDlt26VLy6Ww0hNjfrLprTATmGe+Xd59y53wfH+OjbDIZb4chYi+IekYzNv851FXHLgK7h0YTAYNl4A3nrrre7u7ps3bwLqP6nOZB//+Mdz5H3WQT/9t7g1xNAww2HCEoAZZlwB8OCRY5IA+PCpvWIzzbvYtS4BSNOAfPJPcUrT6iXICgliby+vv87cXIr3536P9I3VdoZlG9vUOehD4c+fPZt/+bIlOQmHkwLg9dLczLFjdHQgGBriwgWuXSMQIBJhdjbZ/2/PHhobefZZXcoD+MP7e0i9S/UrnE92wZQWnuQkaYRC+oDlr71WPj9fAXobUhm9pZWbDL/GazqC4/0/plcBMheAG9y4w50o0UUWt7O94hsVPnyS/7TWpLOL/GAbWORadAFGAAyGTRSAGzduaPkvDXjnnXcAtaLX8l9tYNWNnqzQOvEiF69w5QY3/PjvcCdEaIIJVwDcdqC72V1Djdbp+9l/kIOHOSxtWJ8AiCj8mdP1RQJTT33WAnD1KleucOYM16+73n9155uuAe812831wfpXuyd6e73nzqGpRketeFx9n/H5aGsjFiMvjyMlNzl9GglOXx9SiVDIEYBkA/KWFp2RbmiJ/vBfSEXFkgYUU/GdnPDkl/myNHieeckA9xIMSuTKL18uv3ixvLZWg3RmZQHQDAECL/NyZBdUf1mXpnYK+j1WQ33A3+O9S1waZDBCRAKg+M/7DW8NNbXUSp9kHjzAEEMhQhFGPFws4mvSCQwGw6YKgNb7agKutvRKBAGKA0ZGRtSwm6y4zvVees9x7hKXrnFtkEEgPz+/vLzc6/Hm5ubatp1IJKLR6K3xWwoRCilsokkPbnM7RKiDjvRQIOt3Is8iAdBRL8Ea6e+XAMgc778at1d9sjpUHeuOvfnmdE9PZcHZpiN4CyiYZXYkPvJ+//tvTkTz8uSxQzV573rfeiuvu/tA/rWaQ5SUOM3TFvz+SP+liDJHytORn09ZGQcOkMZCWmNfmdz0QvjSCCOOyeGuJABF0oB/8A/Kf/u3S4LBSZ2Jx5E4pSLx1nBpwBhjVD+nadHkmREn3k33m7x5hjP6G9EMkqJiip0OdHXU6W/HSZFZWH78ffT106+VwS52lVPOClxK/yErnk19ZDB8QAWgsLDQ4/HIQfv9fpAzqtCPOsnaUYqgm+53eEca0EcfsHfv3vr6ejUZ17TFxcV5eXkSAHW+lwCEQqFAIHDr1q2+SJ90YpRRLRUVJShZ4cXL+vha19e++cffvDp91REAHXPIIWNsW2v/pABA0ec+99kf/vAbZMV07/TwO9Pd3Z89dO5TinLkmLWwjRHTR9bjN8JvXL5MY+OVlvkLpb29JxquHTlCfT07dyIBCIXQG3j7bc6di6BIxOtFy+X9+7EsVkc+2nHTly45vlt2nwCEw/L+0gCKi8tFzRsVwf80qet0Rm8gFXcGhDOtjpnRR99ZzvbQc5rTcvTHOa6PP820ZnuFVyqo0N+O4gBH9RU7at0wyugn+aTO6w0/NNqZgR+SBccxAmAwAiBqa2sPHDigVb8cNKDMT2tr6zNyNGvkJjd76NFaTxrgx68m90eOHDl48KCKCpKBysrKkpISVwAUdoyOjkpyrl+/funSpQsXLmig3OICC7nkfoSPlFDCOoi1xn7Nf/wf9vYqEyXvL3uWZ9eU/HFsaIhfbG/9RryFbIm9F/uL3m+d/JkPPX/y+SMcabQaHQ8oscwnP0Kk1z8eCPQHJ6+3e/s6OzlxgoMHJcNIALTu372b+XkpgR4Po5BpcFCPpKusTmWlowGKGIYjw04EkLb8dyIAypcJBv06ky4ActaO6VLH+2fY1HOe+X76FQhe4EIrrZL2AxzQ8n+SSQV8fvwyXaDgoIwyIEJEz77Ii/pF6Xp9gExSbjPwg7V6f1kK/w+D4YMqAKWlpS+88IKyNHL9zppdjlvugLUQIfIjfqQbRd7mbT/+3bt3nzhxor29va2tTeoiOUkvKU9OTmr5f+XKlT179kgtVIU+s3hG63TnBqEP8SHWwUzrzMxAixJbrWM/CQLkXDIaO5P0/goCRsrLv9HSEh9chwD8vP2Rlzrk1DrprKEGG+GxPB10yCm/z/vnphtGRv79v7/m/+IXbS3/pQFu++S6OubmCATQO5HbR054dJSxMUcAMgkCZNHIZUcAxhhLTa/J9TsRQFtbuagor7gcTKqCJCc3FzeH43h/zUB1S3LazAgR0ij5eun6czynX4KsggqFegqAZH78AQJ6IzojtSiiSLO30NJOu4yVaVvpVFYYDEYAnCBAWRpVAgAt1ZWpZ40ocj/PeQX7/fRLUeT9Ozs7dTx27Fi663dQQHD48GHpTVlZmeRnYWGhp6fHWQx68frwNdOcvQC0SABaZwcGxt56yw0C5HPXtPzX7yPxYktcAnC9hexpL6J9Lx33JDRssFCmW95Qn/fllwfb2/0+Hw0N3EdNDQoCFBAgJiaIRqWcZIBbBuDyZdeDuwIQiSR9vdSuqqpyz56qam91QXxHMBh1ztfW3r/8lxN3RYUVOcx9TDE1yeQEE/vw6uM306yCPyCBr6MuSlQaIAEYOT+ix5q/kEIvXl0jtXjw7QBd3MtfQ5YtBoMRAP6cnD/MqfrlKsTfgy74PJmjFZwcZh99ivQBBRC6lUjeX0cehmoDJ0+enJ+fn5qaCofD165dk5YoKSwv0ESThUVWJFoTcwPMDbTaAwOe21fcIKCSSlZDJfHk2l9Hu6qqv6VlzmqZm2sle9rhODSRRhFFcnkFFMBveDxSREpL0ys0FBWxfTuS0YXZWRIJZJkg3XDy9Tt2jESTdeBDHEpZ/sv0vGNJ1+4IwPDw/QKgsXpzzoSaOTPPjHw6zHcxDwVQqM9LCjvYobycbOL8hHRikcUCCqSIueSyGl8jhQ5kmWIwGAF4jzSSp0ohDi8h0v9Zdax6y/8Nblzn+iKLyvYcOnRImZ/jx4+TGao9KFBQ/BFQLry//87cHU2lisIAA5IBsiMHu9W2B1oYGIjd/nMFAY4AnOJUhsv/iQk41mK3tJBose08sue/gM1KSN62sc0RuW3bkpaOZaHzOmLbSXPJrBQ8Gr3qFHKnmfbgcQsAsoMHlwRA4NPV7wbfd867aJQzluo6t/yboQDkuOdW3QqutKu0dF8pBoNh8wXgG6TxY/gLUukEMhSAGLEhhpxqHtDY2Lhv3z6VEyzLgsw9VbVKBSoINzQ0KAiQ69eEmjZ7ARBN0NoqAZBduZHMAskUXnA/NljAyEjKzT8qg8v7yy7sZ71YYPPIcTM2+jyOH5c10ihtc8q/09P3RAD605ouDganHA3QKTf/EyOW9P6yB9G8yglrybZhMBieNAEQEXj5wd5ffJ2VcZaH8hjzzCv7r3KCvkSWxU1EultUA1USkAAECGhCTZsgkU9+9i63pYGBv9IAWxow7wQBjgCsjFv7jceXxEPef58EALCeSg1wb9ksLh6ZGnEFwC3/6knHRDVuFui6KwDu8p+SkuTzVVVkw2oRgCvBBoNhswVgkAcQgSgFrJEw4RAhZ5cYr9er+3+0nGftaJRuB9IMBQUF8Xhcc44xpsmrqCJrapATl/fXDgz9ly5dJXlH0AEOkIbfnxSA99+HAwdsZ/lPipI9zRowcn3IWcsvshgMbnMiAGmcKwD607Gzw0kBSK0Au9kkssRZ/uvIBmtAx5J9HYPB8Bh2A51gQhYhAuzcuVO39Di3kGaBBmq4JnH2D9C0UaKsE2chr2NxsSoBMjn5OHHScGu/5OdrSNKeclzHPcusEwGoIOxEAFNTK0cAcxNFjgDcvTvuLP8jRFwhITsc7y8zGAxbSQBixKaZlgEej0cVXd3fSVYUL6FJAE2omWWsk4oKeX/H5Mvk/R0Z4F6uXUsu/wcGwPX+VVVbRABkRUXJL/QGhx3/nur9nU3rnBNLWSCWbPkLwB5PWgFgo1NADjYGg+FpEoAECceA/CWUwyErNNCZ4b5ps8RKCwIqK90gQBEGyyQSKbXfkpK05b/F08u2ba4GOAn90eDovTeA4uJcp3P3C4CrIpZFFpgisMGwVQXAxl5kUUc0+xJWtm4idbjmdKddL0VF9rIGyO9LABxLr/3K2zlqYevisjK2BO43wvTZwzPh8HB4eHgmGl1BAJzlvyw2XjgysjAyMjb247EQodQCwPojABMEGAxbRwCUOsghR0dgYYlFue6sSB2uOd1pNwAnAtCxttbNAjm7m0WjSQGQKUTY5Oy/9RjLABQWRu5GQqPahenH6d7f+Z27peDR0XHVAMKh8EJhXnoBIPsisMFg2EoCUECBY0B8Ce31RlbMLqEZUqfdqEyIqwFx4k4WSMfU2m8kkpL9LyraOg0pc3PdHM7E6MTdu9HR0eiD9nRwS8FjY5Oh0MREaMINIJAiw/qLwCYIMBi2jgB48BRT7Gzeqe0ctMVbNBolKzR2aglAc2pm2Yb52cbGpAbs23eNa04Q0B/qd5f/Tt8V55rUKbZMECCbvDs5Oqo9nydXjACEGwEEQy1jY1OTY5OkasX6U0AGw1bCCEAppTvZmdzONxIJh8NjY2Osnbm5OQ0cHx/XJEA55ZpTk7NB2KnV4Lw8JwjQl86WvL8Vi+Eu/22FC1sLdxXf/5XAr/961OdzBGCFmm4eeclS8LTvN8d+6lrXwIYKwDbABAGPC4Mhl42mkkov3t3s1rJaW/yrr4Cay8uba+t/1sLt27eDwaCGqwywne2aUzPvYtfGLoTdzSGGLly4Gb3ZP9B/69bta9eW4wNZUxNrpD6LJ+szncNlL6txglXJz0/m8Y9Xw88VFPycz2frp3TcUrCOVX9cxTM4AzWDiQDux2AwAlBFlfxFDTUePNOx6cHBQXWXVF/JtbYUVm8A9YcZGhoC9rLXcUPWRrsMVwBk/iG/f9Cv/+cXt+l81rXfLh5EkyyDMV/gYdRoRJbvIUX8amU+GLQspcGsmpqVV9o11Oxn/1f5KqIafKxj+X8A/heyLLB50jEYjADkkltHXT31jTRe5KJcv/Iq2tOtpqYm82+EqTH91atXtRmc/DHQQIPTKXDj918oK8MNAgLnA0u4yR/27s0iX/8SK9KMbEV+pDFr8P57ZVm8h3QBeKkaZDmwsHt36ge078sCfZyPH+UouY73l5VjMBiMAKyIXH8zzVo29tOvHM7Fixe1I5B2dFBPmEwSQcr8nDlz5vz58319fYAzlY4+fGwoNlggR+8IQPwf+odG/+Du9u/T+VlHALJbdx4jnRydzmDAoezmT6eah7FdebWkO4fAQ+/sqkb/kbRCVsZgMBgBqKCildYhhoIEu+k+e/astgXV13qVzT969OiuVfvHKmKQ91cvsN7eXpUBSilto+0QhzThJqUF5ApdDQjMz1NXl/T+Xi9bGjehA4FML3dGGAyGLUHuJm28qx5+o4yGCU8yeXHh4unTp+X9dUOn2ryoPYD2edY2n5Zlpd7yPzw8rGqBMj9a+7/33ntqDZ9Pfgcdxzh2mMM+fNibtgtnayuDg0Qit51b/g8dQg/Sh201XI+ewb6kVopeGAxbCBMBbLwGFFDQTvsUUwkSFtaF2QuvvfaabglVUVctYlQPUBygkoAyQrZty/tPTExIG1QxVvZfmR9d5ol6ni95/gQnpAGaig3E1YDUT67+5BUVTE+Tn09TEzt2APZW9v7CA39HZuquH3AMJgVkw5twio1jD3te5EVHDHaw4wIXVAxQhkedXqqqqrTVs3b6dAQgHo9Ho9FQKKScj1P1rf2vtUd6jrSfan+h8AVpAGlsfBwgj9/RsVnf1cqBv4FsdQ4t2f/lYXxpyX4Hg8GwUZgaQBz+KfwSG8de9n6YD5dQsotdPnzXuDYQG7i8hHZ50z7PrgDEYjHE59gTLhmdOlDfc7gtr+1E3tHOzo7c3Bw2Exsss/z9YGMwGAFIINtodrP7E3xC0UAddfvZP8hgkGCIUHQxOjM5M8+8s3uEpKKsu8z7htc3F/e98cb/7TmvL+fm5TXl5tLZufqq3AY+z4PJf/DTX4Dv8zC+kD6+BpnBYNhqGAHIhXk2lDzyVMhtoqmf/iGGRhgJE44SnWVWAmBh6QKP7Sm1SysTldUJv29u7n+88UZPT1NeHhIAHV944SHZmK4HvzZd2QQB9oPn9jmnDAbDVsEIwOKyAMyzOZRSeoQjsjHGxhmfZPInAmDnFVFUapVWnKgomXuHuTkSidhpq6dH3j9p7e1r/95Tvp7IJhFkP3juGudng8GwhTAC4Hj/OEvYNkksi41G9QDZyrn2fDhxQgLg2MS770oDnCBA1tbGgyjI9GwWFKT/YDAYthJGAOJLlgAWF5meJhZjdhaKCikspKCAR4bHo4yPqwFjZ8+6cYCU4ODBTa8G23zAMBgMJgK4eTMxNZUAxse5cYNgkEQCnvFSXs7OnZvodNMpK5MG6OUdG+nrkwa49YB9+9gwzJ0/BoPBCMDwcOLllxOBQAKYnOTmTS5cgPx8mpupq8Pn4xHj9bq5IHn9QDicmguqryczSuAfIdtAGuG/IDMYDFsEIwCz44noaOLPv5GYgOlpgkGorKSzjWPHlHbZLAGwH9a0RBpgWehBNNoPebK+pAbU1LAeDAaDwZDLKzBEYiiRCCTiTZU3pjsRh4upqmL/fo4epaODR4vFMs88Q1kZgQCxGLZ9DXIdGbhDZy579mAwGAyGrMnloxAhPhSPBw4n7lYjV2tZFBWhCKC+Xsv/x5xuLy1FtsxlRwAgF05BBevBYDAYTAqojETZc4m25xLRKDMzSAC2b6ekhCeS88sCoOMp/rKdO+BQIIgCOP5mupRGYQpQxSEFEZAAhPvcg44OKAClQGkXxoJb2BubAw539txp+v889OYL/GVqpCMVAAB3APltOh0J8wcKqeLtMwBhXgQAUD0A8v+UfMvrbwUAAAjAezk/VtzlL/EBAKooCnk8AAAtAIBoEAAAAAEAABAAAAABAAA8yVeyLNvtdpfLRSnV7/dns1mj0ZC4AQAByPPcObderw+HQ61WG4/H3vvVaiVxAwACsN/vt9utc26z2dTr9cVi0W63n0sCIGIgAN77JEmOx2NeOp1OYQ2HAiBu4BK42WwaY6y1tzV8CGs4FABxA98AhsPhZDK5Xq+9Xk9rPZ1OwzoajQRA3EAArLXL5dIYcz6flVKDwWA+n7daLQHwCMBjcOE8TVOtdbfbFQAAr4ECAPgnMACAAAAA7s0HoDFhsamH/bcAAAAASUVORK5CYII=",pU={thin:100,light:300,regular:400,normal:400,medium:500,bold:700,black:900};class gU{constructor(t){this._webGLHelper=t,this.fontRepository="https://raw.githubusercontent.com/etiennepinchon/aframe-fonts/master/fonts/",this._fonts=new gi([],JSON.stringify),this._metadataPromises=new Map,this._fontPromises=new Map,this._promises=[],this._defaultFontEntry={metrics:Om(bE),texture:t?this._createTextureNow(dU):void 0}}async waitUntilReady(){await Promise.all(this._promises)}getFont(t,n="normal",r="regular"){if(Me(r)&&(r=pU[r.toLowerCase()],!r))throw new Error("Unknown font weight: "+r);const i={family:t,style:n,weight:r};let a=this._fonts.get(i);return a||(a={metrics:void 0,texture:void 0},this._fonts.set(i,a),this._promises.push(this._loadFontEntry(a,i))),a}async _loadFontEntry(t,n){try{const r=await this._loadMetadata(n.family),i=bU(r,n),a=this.fontRepository+NE(n.family)+"/"+i.replace(/\.\w+/,""),o=this._createTexture(a+".png"),s=this._loadFont(a+".json");t.texture=await o,t.metrics=await s}catch(r){console.log("Cannot load font. Using default.",r),t.metrics=this._defaultFontEntry.metrics,t.texture=this._defaultFontEntry.texture}}_loadFont(t){let n=this._fontPromises.get(t);return n||(n=fetch(t).then(r=>{if(!r.ok)throw new Error("Could not load font: "+r.status);return r}).then(r=>r.json()).then(r=>Om(r)),this._fontPromises.set(t,n)),n}_loadMetadata(t){const n=NE(t);let r=this._metadataPromises.get(n);return r||(r=fetch(this.fontRepository+n+"/METADATA.pb").then(i=>{if(!i.ok)throw new Error("Could not load font metadata: "+i.status);return i}).then(i=>i.text()).then(i=>mU(i)).catch(i=>{console.warn(i)}),this._metadataPromises.set(n,r)),r}getDefaultFont(){return this._defaultFontEntry}_createTexture(t){const n=this._webGLHelper.gl;return new Promise((r,i)=>{kl(n,{src:t,min:n.LINEAR},(a,o,s)=>{a?i(a):r(o)})})}_createTextureNow(t){const n=this._webGLHelper.gl;let r;const i=new Promise((a,o)=>{r=kl(n,{src:t,min:n.LINEAR},(s,c,l)=>{s?o(s):a(c)})});return this._promises.push(i),r}}function NE(e){return e.toLowerCase().replaceAll(/[^\w]/g,"")}function mU(e){const t=e.split(`
|
|
1715
|
+
`),n=[];let r;for(const i of t)if(i.startsWith("fonts {")&&(r={name:void 0,style:void 0,weight:void 0,filename:void 0,post_script_name:void 0,full_name:void 0,copyright:void 0}),i.startsWith("}")&&(n.push(r),r=void 0),r){let a=i.match(/^\s*([A-Za-z_]+):[ ]?"(.*)"$/);if(a){const o=a[1];r[o]=a[2]}if(a=i.match(/^\s*([A-Za-z_]+):[ ]?(\d+)$/),a){const o=a[1];r[o]=+a[2]}}return n}function bU(e,t){let n,r=Number.POSITIVE_INFINITY;for(const i of e)if(t.family.localeCompare(i.name,void 0,{sensitivity:"accent"})==0&&t.style==i.style){const a=Math.abs(t.weight-i.weight);a<r&&(r=a,n=i)}return n==null?void 0:n.filename}function yU(e,t){const n=[];let r;for(const i of e.split(`
|
|
1716
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+
`))if(i.startsWith(">"))r={identifier:i.match(/>(\S+)/)[1],sequence:""},n.push(r);else if(r)r.sequence+=i.trim();else throw new Error("Invalid fasta file!");return n}class vU{constructor(t,n){this.animator=t,this.disabled=!!n,this.damping=.015,this.acceleration=.3,this.accelerationThreshold=100,this.lowerLimit=.5,this.loop=!1,this.momentum=0,this.timestamp=0,this.callback=null,this._transitionCallback=this.animate.bind(this),this.clear()}clear(){this.momentum=0,this.timestamp=null,this.loop=null,this.callback=null}cancel(){this.loop&&(this.animator.cancelTransition(this._transitionCallback),this.clear())}setMomentum(t,n){if(this.disabled){n(t);return}t*this.momentum<0?this.momentum=0:Math.abs(t)>this.accelerationThreshold?this.momentum=dv([this.momentum,t],this.acceleration):this.momentum=t,this.callback=n,this.loop||this.animate()}animate(t){this.callback(this.momentum);const n=t-this.timestamp||0;this.timestamp=t;const r=Math.abs(this.momentum);this.momentum=Math.sign(this.momentum)*Math.max(0,r-((r*this.damping)**1.5+.04)*n),Math.abs(this.momentum)>this.lowerLimit?(this.loop=!0,this.animator.requestTransition(this._transitionCallback)):this.clear()}}function wU(e){const t={},n=["string","number","boolean"],r=["wheelDelta","wheelDeltaX","wheelDeltaY"];for(const i in e){const a=i;!r.includes(i)&&n.includes(typeof e[a])&&(t[a]=e[a])}return t}const zE=new Map;async function xU(e,t,n){const r=e.symbol;let i=zE.get(r)??await SU(e.symbol);return i?(zE.set(r,i),$`
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-
`:"";return $`${s}${a}`}class Ka extends Yn{constructor(n,r,i,a,o,s){super(n,r,i,a,o,s);Z(this,si,[]);this.spec=n,this.needsAxes={x:!0,y:!0}}async initializeChildren(){le(this,si,await Promise.all(this.spec.layer.map((n,r)=>this.context.createOrImportView(n,this,this,"grid"+r,i=>{if(!od(i)&&!ad(i))throw new Za("LayerView accepts only unit or layer specs as children!",this)}))))}get children(){return F(this,si).slice()}*[Symbol.iterator](){for(const n of F(this,si))yield n}render(n,r,i={}){if(super.render(n,r,i),!!this.isConfiguredVisible()){n.pushView(this,r);for(const a of F(this,si))a.render(n,r,i);n.popView(this)}}propagateInteractionEvent(n){this.handleInteractionEvent(void 0,n,!0);for(let r=F(this,si).length-1;r>=0;r--)if(F(this,si)[r].propagateInteractionEvent(n),n.stopped)return;this.handleInteractionEvent(void 0,n,!1)}}si=new WeakMap;class UE{constructor(t,n){this.n=t,this.maxCols=n??1/0}get nRows(){return this.maxCols==1/0?1:Math.ceil(this.n/this.maxCols)}get nCols(){return Math.min(this.n,this.maxCols)}get rowIndices(){const t=[],n=this.nCols,r=this.nRows;for(let i=0;i<r;i++){const a=[];t.push(a);for(let o=0;o<n;o++){const s=i*n+o;s<this.n&&a.push(s)}}return t}get colIndices(){const t=[],n=this.nCols,r=this.nRows;for(let i=0;i<n;i++){const a=[];t.push(a);for(let o=0;o<r;o++){const s=o*n+i;s<this.n&&a.push(s)}}return t}getCellIndex(t,n){let r=0;if(this.maxCols==1/0)r=n==0?t:void 0;else{if(t>=this.maxCols)return;r=n*this.nCols+t}return r<this.n?r:void 0}getCellCoords(t){if(!(t<0||t>=this.n))return[t%this.nCols,Math.floor(t/this.nCols)]}}const kU="chromosome_ticks_and_labels",TU={x:"width",y:"height"};function e1(e){return e=="x"?"y":"x"}const id={x:["bottom","top"],y:["left","right"]},t1=Object.fromEntries(Object.entries(id).map(([e,t])=>t.map(n=>[n,e])).flat(1));function Ni(e){return t1[e]}class n1 extends Ka{constructor(t,n,r,i,a,o){const s=n=="locus",c={...s?RU:$E,...IU(n,t),...t};super(s?DU(c,n):HE(c,n),r,i,a,`axis_${t.orient}`,{blockEncodingInheritance:!0,contributesToScaleDomain:!1,...o}),this.axisProps=c}getSize(){const t={px:this.getPerpendicularSize()},n={grow:1};return t1[this.axisProps.orient]=="x"?new Gr(n,t):new Gr(t,n)}getPerpendicularSize(){return r1(this.axisProps)}isPickingSupported(){return!1}}function r1(e){const t=Ni(e.orient);let n=e.ticks&&e.tickSize||0;return e.labels&&(n+=e.labelPadding,t=="x"?n+=e.labelFontSize:n+=30),e.title&&(n+=e.titlePadding+e.titleFontSize),n=Math.min(e.maxExtent||1/0,Math.max(e.minExtent||0,n)),n}const $E={values:null,minExtent:20,maxExtent:1/0,offset:0,domain:!0,domainWidth:1,domainColor:"gray",domainDash:null,domainDashOffset:0,domainCap:"square",ticks:!0,tickSize:5,tickWidth:1,tickColor:"gray",tickDash:null,tickDashOffset:0,tickCap:"square",tickCount:null,tickMinStep:null,labels:!0,labelAlign:"center",labelBaseline:"middle",labelPadding:4,labelFontSize:10,labelLimit:180,labelColor:"black",format:null,titleColor:"black",titleFont:"sans-serif",titleFontSize:10,titlePadding:3};function IU(e,t){const n=t.orient,r=e=="nominal"||e=="ordinal";let i="center",a="middle",o=t.labelAngle??((n=="top"||n=="bottom")&&r?-90:0);switch(n){case"left":i="right";break;case"right":i="left";break;case"top":case"bottom":Math.abs(o)>30?(i=o>0==(n=="bottom")?"left":"right",a="middle"):a=n=="top"?"alphabetic":"top";break}return{labelAlign:i,labelAngle:o,labelBaseline:a}}function HE(e,t){const n={...e,extent:r1(e)},r=Ni(n.orient),i=e1(r),a=n.orient=="bottom"||n.orient=="right"?1:-1,o=n.orient=="bottom"||n.orient=="left"?1:0,s=()=>({name:"domain",data:{values:[0]},mark:{type:"rule",clip:!1,strokeDash:n.domainDash,strokeCap:n.domainCap,color:n.domainColor,[i]:o,size:n.domainWidth}}),c=()=>({name:"labels",mark:{type:"text",clip:!1,align:n.labelAlign,angle:n.labelAngle,baseline:n.labelBaseline,[i+"Offset"]:(n.tickSize+n.labelPadding)*a,[i]:o,size:n.labelFontSize,color:n.labelColor,minBufferSize:1500},encoding:{[r]:{field:"value",type:t},text:{field:"label"}}}),l=()=>({name:"ticks",mark:{type:"rule",clip:!1,strokeDash:n.tickDash,strokeCap:n.tickCap,color:n.tickColor,size:n.tickWidth,minBufferSize:300},encoding:{[i]:{value:o},[i+"2"]:{value:o-n.tickSize/n.extent*(o?1:-1)}}}),u=()=>({name:"title",data:{values:[0]},mark:{type:"text",clip:!1,align:"center",baseline:n.orient=="bottom"?"bottom":"top",angle:[0,90,0,-90][["top","right","bottom","left"].indexOf(n.orient)],text:n.title,color:n.titleColor,[r]:.5,[i]:1-o}}),f=()=>{const d={name:"ticks_and_labels",encoding:{[r]:{field:"value",type:t}},layer:[]};return n.ticks&&d.layer.push(l()),n.labels&&d.layer.push(c()),d},h={resolve:{scale:{[r]:"forced"}},[TU[e1(r)]]:n.extent,data:{lazy:{type:"axisTicks",channel:r,axis:e}},layer:[]};return n.domain&&h.layer.push(s()),(n.ticks||n.labels)&&h.layer.push(f()),n.title&&h.layer.push(u()),h}const RU={...$E,chromTicks:!0,chromTickSize:18,chromTickWidth:1,chromTickColor:"#989898",chromTickDash:[4,2],chromTickDashOffset:1,chromLabels:!0,chromLabelFontSize:13,chromLabelFontWeight:"normal",chromLabelFontStyle:"normal",chromLabelColor:"black",chromLabelAlign:"left",chromLabelPadding:7};function DU(e,t){const n={...e,extent:r1(e)},r=Ni(n.orient),i=e1(r),a=n.orient=="bottom"||n.orient=="left"?1:0,o=()=>({name:"chromosome_ticks",mark:{type:"rule",strokeDash:e.chromTickDash,strokeDashOffset:e.chromTickDashOffset,[i]:a,[i+"2"]:a-n.chromTickSize/n.extent*(a?1:-1),color:e.chromTickColor,size:n.chromTickWidth}}),s=()=>{let u;switch(n.orient){case"top":u={y:0,angle:0,paddingX:4,dy:-n.chromLabelPadding,viewportEdgeFadeWidthLeft:20,viewportEdgeFadeWidthRight:20,viewportEdgeFadeDistanceRight:-10,viewportEdgeFadeDistanceLeft:-20};break;case"bottom":u={y:1,angle:0,paddingX:4,dy:n.chromLabelPadding+n.chromLabelFontSize*.73,viewportEdgeFadeWidthLeft:20,viewportEdgeFadeWidthRight:20,viewportEdgeFadeDistanceRight:-10,viewportEdgeFadeDistanceLeft:-20};break;case"left":u={x:1,angle:-90,paddingY:4,dy:-n.chromLabelPadding,viewportEdgeFadeWidthBottom:20,viewportEdgeFadeWidthTop:20,viewportEdgeFadeDistanceBottom:-20,viewportEdgeFadeDistanceTop:-10};break;case"right":u={x:0,angle:90,align:"right",paddingY:4,dy:-n.chromLabelPadding};break;default:u={}}return{name:"chromosome_labels",mark:{type:"text",size:n.chromLabelFontSize,font:n.chromLabelFont,fontWeight:n.chromLabelFontWeight,fontStyle:n.chromLabelFontStyle,color:n.chromLabelColor,align:e.chromLabelAlign,baseline:"alphabetic",clip:!1,...u},encoding:{[r+"2"]:{field:"continuousEnd",type:t},text:{field:"name"}}}};let c;switch(n.orient){case"bottom":case"top":c={};break;case"left":c={labelAngle:-90,labelAlign:"center",labelPadding:6};break;case"right":c={labelAngle:90,labelAlign:"center",labelPadding:6};break;default:c={}}const l=HE({...e,...c},t);if(e.chromTicks||e.chromLabels){const u={name:kU,data:{lazy:{type:"axisGenome",channel:Ni(n.orient)}},encoding:{[r]:{field:"continuousStart",type:t,band:0}},layer:[]};if(e.chromTicks&&u.layer.push(o()),e.chromLabels){u.layer.push(s());let f;l.layer.filter(h=>h.name=="ticks_and_labels").forEach(h=>h.layer.filter(d=>d.name=="labels").forEach(d=>{f=d.mark})),f&&(n.orient=="top"||n.orient=="bottom"?(f.viewportEdgeFadeWidthLeft=30,f.viewportEdgeFadeDistanceLeft=40):(f.viewportEdgeFadeWidthBottom=30,f.viewportEdgeFadeDistanceBottom=40))}l.layer.push(u)}return l}class BU extends Ka{constructor(t,n,r,i,a,o){const c={...n=="locus"?FU:GE,...t};super(LU(c,n),r,i,a,`axisGrid_${t.orient}`,{blockEncodingInheritance:!0,contributesToScaleDomain:!1,...o}),this.axisProps=c}getOrient(){return this.axisProps.orient}isPickingSupported(){return!1}}const GE={values:null,grid:!1,gridCap:"butt",gridColor:"lightgray",gridDash:null,gridOpacity:1,gridWidth:1,tickCount:null,tickMinStep:null},FU={...GE,chromGrid:!1,chromGridCap:"butt",chromGridColor:"gray",chromGridDash:[1,5],chromGridOpacity:1,chromGridWidth:1};function PU(e,t){const n=e,r=Ni(n.orient);return{name:"grid_lines",data:{lazy:{type:"axisTicks",channel:r,axis:e}},mark:{type:"rule",strokeDash:n.gridDash,strokeCap:n.gridCap,color:n.gridColor,size:n.gridWidth,opacity:n.gridOpacity,minBufferSize:300},encoding:{[r]:{field:"value",type:t}}}}function MU(e,t){const n=e,r=Ni(n.orient);return{name:"chromosome_lines",data:{lazy:{type:"axisGenome",channel:r}},mark:{type:"rule",strokeDash:n.chromGridDash,strokeCap:n.chromGridCap,color:n.chromGridColor,size:n.chromGridWidth,opacity:n.chromGridOpacity},encoding:{[r]:{field:"continuousStart",type:t,band:0}}}}function OU(e,t){const n=e,r=Ni(n.orient);return{name:"chromosome_fill",data:{lazy:{type:"axisGenome",channel:r}},mark:{type:"rect"},encoding:{[r]:{field:"continuousStart",type:t,band:0},[r+"2"]:{field:"continuousEnd",band:0},fill:{field:"odd",type:"nominal",scale:{domain:[!1,!0],range:[n.chromGridFillEven??"white",n.chromGridFillOdd??"white"]}},opacity:{field:"odd",type:"nominal",scale:{type:"ordinal",domain:[!1,!0],range:[n.chromGridFillEven?1:0,n.chromGridFillOdd?1:0]}}}}}function LU(e,t){const n={...e},r=[];return n.chromGrid&&(n.chromGridFillOdd||n.chromGridFillEven)&&r.push(OU(n,t)),n.chromGrid&&n.chromGridOpacity>0&&r.push(MU(n,t)),n.grid&&n.gridOpacity>0&&r.push(PU(n,t)),{name:"grid_layers",configurableVisibility:!1,resolve:{scale:{[Ni(e.orient)]:"forced",fill:"independent",opacity:"independent"}},layer:r}}const VE={anchor:"middle",frame:"group",offset:10,orient:"top",align:void 0,angle:0,baseline:"alphabetic",dx:0,dy:0,color:void 0,font:void 0,fontSize:12,fontStyle:"normal",fontWeight:"normal"},NU={orient:"left",anchor:"middle",align:"right",baseline:"middle",angle:0,fontSize:12},zU={orient:"top",anchor:"start",align:"left",baseline:"top",offset:-10,dx:10,fontSize:12},UU={start:0,middle:.5,end:1},$U={start:"left",middle:"center",end:"right"};function HU(e){if(!e)return;const t=Me(e)?{text:e}:e;if(!t.text||t.orient=="none")return;const n={"track-title":NU,overlay:zU}[t.style]??{},r={...VE,...n,...t};let i={},a={x:0,y:0};const o=UU[r.anchor??"middle"];switch(r.orient){case"top":a={x:o,y:1},i={baseline:"alphabetic",angle:0};break;case"right":a={x:1,y:1-o},i={baseline:"alphabetic",angle:90};break;case"bottom":a={x:o,y:0},i={baseline:"top",angle:0};break;case"left":a={x:0,y:o},i={baseline:"alphabetic",angle:-90};break}const s={...VE,...i,...n,...t},c={xOffset:0,yOffset:0};switch(r.orient){case"top":c.yOffset=-s.offset;break;case"right":c.xOffset=s.offset;break;case"bottom":c.yOffset=s.offset;break;case"left":c.xOffset=-s.offset;break}return{configurableVisibility:!1,data:{values:[{}]},mark:{type:"text",tooltip:null,clip:!1,...a,...c,text:s.text,align:s.align??$U[s.anchor],angle:s.angle,baseline:s.baseline,dx:s.dx,dy:s.dy,color:s.color,font:s.font,size:s.fontSize,fontStyle:s.fontStyle,fontWeight:s.fontWeight}}}function jE(e,t,n,r){if(e.type=="wheel"){e.uiEvent.preventDefault();const i=e.uiEvent,a=i.deltaMode?120:1;let{x:o,y:s}=e.point;if(r){const c=r.mark.encoders;c.x&&!c.x2&&!c.x.constantValue&&(o=+c.x(r.datum)*t.width+t.x),c.y&&!c.y2&&!c.y.constantValue&&(s=(1-+c.y(r.datum))*t.height+t.y)}Math.abs(i.deltaX)<Math.abs(i.deltaY)?n({x:o,y:s,xDelta:0,yDelta:0,zDelta:i.deltaY*a/300}):n({x:o,y:s,xDelta:-i.deltaX*a,yDelta:0,zDelta:0})}else if(e.type=="mousedown"&&e.uiEvent.button===0){const i=e.uiEvent;i.preventDefault();let a=i;const o=c=>{n({x:a.clientX,y:a.clientY,xDelta:c.clientX-a.clientX,yDelta:c.clientY-a.clientY,zDelta:0}),a=c},s=c=>{document.removeEventListener("mousemove",o),document.removeEventListener("mouseup",s)};document.addEventListener("mouseup",s,!1),document.addEventListener("mousemove",o,!1)}}class GU extends Yn{constructor(n,r,i,a,o,s,c){super(n,r,i,a,o,c);Z(this,ci);Z(this,X0);Z(this,Lo);Z(this,gf);Z(this,mf);Z(this,bf);Z(this,K0);Z(this,yc);Z(this,J0);Z(this,gc,1/0);Z(this,mc,10);Z(this,vn,[]);Z(this,Oo,{});Z(this,bc,0);this.spec=n,le(this,mc,n.spacing??10),le(this,gc,s),le(this,vn,[]),this.wrappingFacet=!1}appendChild(n){n.layoutParent??(n.layoutParent=this),F(this,vn).push(new a1(n,this,F(this,bc))),UT(this,bc)._++}setChildren(n){le(this,vn,[]);for(const r of n)this.appendChild(r)}replaceChild(n,r){const i=F(this,vn).findIndex(a=>a.view==n);if(i>=0)F(this,vn)[i]=new a1(r,this,F(this,bc));else throw new Error("Not my child view!")}get children(){return F(this,vn).map(n=>n.view)}get childCount(){return F(this,vn).length}async createAxes(){const n=[];for(const r of ns){const i=this.resolutions.axis[r];if(i){const a=i.getAxisProps();if(a){const o={title:i.getTitle(),orient:id[r][0],...a},s=new 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F(this,ci,Go).entries()){const{view:h,axes:d,gridLines:p,background:g,backgroundStroke:b,title:y}=f,[w,A]=c.getCellCoords(u),x=o[J(this,bf,rv).call(this,"column",w)],C=s[J(this,bf,rv).call(this,"row",A)],_=h.getViewportSize(),I=h.getSize(),D=h.getOverhang(),M=x.location-D.left,G=C.location-D.top,O=(Ve,N)=>(Ve[N].grow?(N=="width"?x:C).size:Ve[N].px)+D[N],ae=O(_,"width"),se=O(_,"height"),ve=O(I,"width"),Pe=O(I,"height"),st=f.scrollbars.horizontal,Ne=f.scrollbars.vertical,lt=st?()=>l(st.viewportOffset):()=>0,tt=Ne?()=>l(Ne.viewportOffset):()=>0,ut=new Zn(()=>r.x+M,()=>r.y+G,()=>ae,()=>se),Te=h.isScrollable(),Ie=Te?new Zn(()=>r.x+M-lt(),()=>r.y+G-tt(),()=>ve,()=>Pe):ut;f.coords=ut;const Rt=i.clipRect?ut.intersect(i.clipRect):ut;g==null||g.render(n,Rt,{...i,clipRect:void 0});for(const Ve of Object.values(p))Ve.render(n,ut,i);const ln=jU(h)||Te;ln&&h.render(n,Ie,{...i,clipRect:Rt}),b==null||b.render(n,Rt,{...i,clipRect:void 0});for(const[Ve,N]of Object.entries(d)){const L=Ve=="left"||Ve=="right"?"vertical":"horizontal",W=f.scrollbars[L],j=W?ut.modify(L=="vertical"?{y:()=>Ie.y,height:Pe}:{x:()=>Ie.x,width:ve}):ut,Q=i1(j,Ve,N);let T=i.clipRect;W&&(T=Q.intersect(T).intersect(W?ut.modify(L=="vertical"?{x:-1e5,width:2e5}:{y:-1e5,height:2e5}):void 0)),N.render(n,Q,{...i,clipRect:T})}for(const Ve of Object.values(F(this,Oo))){const L=Ve.axisProps.orient;(L=="left"&&w==0||L=="right"&&w==c.nCols-1||L=="top"&&A==0||L=="bottom"&&A==c.nRows-1)&&Ve.render(n,i1(ut.shrink(f.view.getOverhang()),L,Ve),i)}ln||h.render(n,Ie,i);for(const Ve of Object.values(f.scrollbars))Ve.updateScrollbar(ut,Ie),Ve.render(n,r,i);y==null||y.render(n,ut,i)}n.popView(this)}propagateInteractionEvent(n){if(this.handleInteractionEvent(void 0,n,!0),n.stopped)return;const r=F(this,ci,Go).find(a=>a.coords.containsPoint(n.point.x,n.point.y));for(const a of Object.values((r==null?void 0:r.scrollbars)??{}))if(a.coords.containsPoint(n.point.x,n.point.y)&&(a.propagateInteractionEvent(n),n.stopped))return;const i=r==null?void 0:r.view;i&&(i.propagateInteractionEvent(n),(i instanceof mt||i instanceof Ka)&&jE(n,r.coords,a=>J(this,J0,YT).call(this,r.coords,r.view,a),this.context.getCurrentHover())),!n.stopped&&this.handleInteractionEvent(void 0,n,!1)}getDefaultResolution(n,r){return"independent"}}gc=new WeakMap,mc=new WeakMap,vn=new WeakMap,Oo=new WeakMap,bc=new WeakMap,ci=new WeakSet,Go=function(){return F(this,vn).filter(n=>n.view.isConfiguredVisible())},X0=new WeakSet,qT=function(){return new UE(F(this,ci,Go).length,F(this,gc)??1/0)},Lo=new WeakSet,If=function(n){const r=n=="column"?"width":"height",i=(a,o)=>a.map(s=>{const l=F(this,ci,Go)[s].getOverhangAndPadding();return n=="column"?o?l.right:l.left:o?l.bottom:l.top}).reduce((s,c)=>Math.max(s,c),0);return this._cache(`size/directionSizes/${n}`,()=>F(this,X0,qT)[n=="column"?"colIndices":"rowIndices"].map(a=>({axisBefore:i(a,0),axisAfter:i(a,1),view:YL(a.map(o=>F(this,ci,Go)[o].view.getViewportSize()[r]))})))},gf=new WeakSet,tv=function(n){const r=J(this,Lo,If).call(this,n),i=[];i.push(Pl);for(const[a,o]of r.entries())a>0&&i.push({px:F(this,mc),grow:0}),(a==0||this.wrappingFacet)&&i.push(Pl),i.push({px:o.axisBefore,grow:0}),i.push(o.view),i.push({px:o.axisAfter,grow:0}),(a==r.length-1||this.wrappingFacet)&&i.push(Pl);return i},mf=new WeakSet,nv=function(n){let r=0,i=0;const a=n=="row"?this.spec.height:this.spec.width;if(a||a===0)return QA(a);const o=J(this,Lo,If).call(this,n);for(const[s,c]of o.entries())s>0&&(i+=F(this,mc)),(s==0||this.wrappingFacet)&&(i+=0),i+=c.axisBefore,i+=c.view.px??0,r+=c.view.grow??0,i+=c.axisAfter,(s==o.length-1||this.wrappingFacet)&&(i+=0);return{px:i,grow:r}},bf=new WeakSet,rv=function(n,r){return n=="row"&&this.wrappingFacet?1+6*r+2:2+4*r+1},K0=new WeakSet,WT=function(){const n=J(this,Lo,If).call(this,"column"),r=J(this,Lo,If).call(this,"row");return!n.length||!r.length?Ct.zero():new Ct(r.at(0).axisBefore,n.at(-1).axisAfter,r.at(-1).axisAfter,n.at(0).axisBefore)},yc=new WeakSet,vp=function(){const n=r=>{const i=t1[r],a=F(this,Oo)[i];return(a==null?void 0:a.axisProps.orient)!==r?0:Math.max(a.getPerpendicularSize()+a.axisProps.offset,0)};return new Ct(n("top"),n("right"),n("bottom"),n("left"))},J0=new WeakSet,YT=function(n,r,i){for(const[a,o]of Object.entries(VU(r))){if(o.size<=0)continue;const s=n.normalizePoint(i.x,i.y),c=n.normalizePoint(i.x+i.xDelta,i.y+i.yDelta),l={x:c.x-s.x,y:c.y-s.y};for(const u of o)u.zoom(2**i.zDelta,a=="y"?1-s[a]:s[a],a=="x"?l.x:-l.y)}this.context.animator.requestRender()};function qE(e){if(!(!e||!e.fill||e.fillOpacity===0))return{configurableVisibility:!1,data:{values:[{}]},mark:{color:e.fill,opacity:e.fillOpacity??1,type:"rect",clip:!1,tooltip:null,minHeight:1,minOpacity:0}}}function WE(e){if(!(!e||!e.stroke||e.strokeWidth===0||e.strokeOpacity===0))return{configurableVisibility:!1,resolve:{scale:{x:"excluded",y:"excluded"},axis:{x:"excluded",y:"excluded"}},data:{values:[{x:0,y:0,x2:1,y2:0},{x:1,y:0,x2:1,y2:1},{x:1,y:1,x2:0,y2:1},{x:0,y:1,x2:0,y2:0}]},mark:{size:e.strokeWidth??1,color:e.stroke??"lightgray",strokeCap:"square",strokeOpacity:e.strokeOpacity??1,type:"rule",clip:!1,tooltip:null},encoding:{x:{field:"x",type:"quantitative",scale:null},y:{field:"y",type:"quantitative",scale:null},x2:{field:"x2"},y2:{field:"y2"}}}}function VU(e){const t={x:new Set,y:new Set};return e.visit(n=>{for(const[r,i]of Object.entries(t)){const a=n.getScaleResolution(r);a&&a.isZoomable()&&i.add(a)}}),t}function jU(e){let t=!0;return e.visit(n=>{n instanceof mt&&t&&(t=n.mark.properties.clip===!0)}),t}function i1(e,t,n){const r=n.axisProps,i=n.getPerpendicularSize();if(t=="bottom")return e.translate(0,e.height+r.offset).modify({height:i});if(t=="top")return e.translate(0,-i-r.offset).modify({height:i});if(t=="left")return e.translate(-i-r.offset,0).modify({width:i});if(t=="right")return e.translate(e.width+r.offset,0).modify({width:i})}class a1{constructor(t,n,r){if(this.layoutParent=n,this.view=t,this.serial=r,this.background=void 0,this.backgroundStroke=void 0,this.axes={},this.gridLines={},this.scrollbars={},this.title=void 0,this.coords=Zn.ZERO,t.needsAxes.x||t.needsAxes.y){const i=t.spec,a="view"in i?i==null?void 0:i.view:void 0,o=qE(a);o&&(this.background=new mt(o,n.context,n,t,"background"+r,{blockEncodingInheritance:!0}));const s=WE(a);s&&(this.backgroundStroke=new mt(s,n.context,n,t,"backgroundStroke"+r,{blockEncodingInheritance:!0}));const c=HU(t.spec.title);if(c){const l=new mt(c,n.context,n,t,"title"+r,{blockEncodingInheritance:!0});this.title=l}}t.spec.viewportWidth!=null&&(this.scrollbars.horizontal=new YE(this,"horizontal")),t.spec.viewportHeight!=null&&(this.scrollbars.vertical=new YE(this,"vertical"))}*getChildren(){this.background&&(yield this.background),this.backgroundStroke&&(yield this.backgroundStroke),this.title&&(yield this.title),yield*Object.values(this.axes),yield*Object.values(this.gridLines),yield this.view,yield*Object.values(this.scrollbars)}async createAxes(){const{view:t,axes:n,gridLines:r}=this,i=(s,c)=>{const l=s.getAxisProps();if(l===null)return;const u=l?{...l}:{};if(!u.orient){for(const f of id[c])if(!n[f]){u.orient=f;break}if(!u.orient)throw new Error("No slots available for an axis! 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Use @genome-spy/app instead!")})}addViewType(t,n){F(this,vc).set(t,n)}createView(t,n,r,i,a){for(const[o,s]of F(this,vc))if(o(t))return s(t,n,r,i,a);throw new Error("Invalid spec, cannot figure out the view type from the properties: "+JSON.stringify([...Object.keys(t)]))}isViewSpec(t){const n=[...F(this,vc).keys()].filter(r=>r(t));if(n.length>1)throw new Error("Ambiguous spec. Cannot create a view!");return n.length==1}async createOrImportView(t,n,r,i,a,o){let s;if(YU(t))if(this.options.allowImport)s=await rU(t,i.getBaseUrl(),n),o&&o(s);else throw new Za("Importing views is not allowed!",r);else s=t;!i&&this.options.wrapRoot&&(ad(s)||od(s))&&a===ZE&&(s={name:"implicitRoot",vconcat:[s]});const c=this.createView(s,n,r,i,a);return c instanceof Yn&&await c.initializeChildren(),c}}vc=new WeakMap;function ad(e){return"mark"in e&&(Me(e.mark)||Xt(e.mark))}function od(e){return"layer"in e&&Xt(e.layer)}function WU(e){return e&&(ad(e)||od(e))&&"aggregateSamples"in e}function YU(e){return"import"in e}function sd(e){return"vconcat"in e&&Qt(e.vconcat)}function QE(e){return"hconcat"in e&&Qt(e.hconcat)}function o1(e){return"concat"in e&&Qt(e.concat)}function XE(e){return"samples"in e&&Xt(e.samples)&&"spec"in e&&Xt(e.spec)}class ZU{constructor(){Z(this,wc,void 0);Z(this,No,void 0);Z(this,yf,void 0);Z(this,zo,void 0);le(this,wc,new Map),le(this,No,new Set),le(this,zo,new Map),le(this,yf,new Proxy(F(this,wc),{get(t,n){return Me(n)?t.get(n):void 0}}))}allocateSetter(t){if(F(this,No).has(t))throw new Error("Setter already allocated for parameter: "+t);return F(this,No).add(t),n=>{F(this,wc).set(t,n);const r=F(this,zo).get(t);if(r)for(const i of r)i()}}createExpression(t){const n=ch(t,F(this,yf));for(const r of n.globals)if(!F(this,No).has(r))throw new Error(`Unknown variable "${r}" in expression: ${t}`);return n.addListener=r=>{for(const i of n.globals){const a=F(this,zo).get(i)??new Set;F(this,zo).set(i,a),a.add(r)}},n}}wc=new WeakMap,No=new WeakMap,yf=new WeakMap,zo=new WeakMap,hw("fasta",bU);class KE{constructor(t,n,r={}){this.container=t,this._destructionCallbacks=[];const i=document.createElement("style");i.innerHTML=fD,t.appendChild(i),this.spec=n,this.accessorFactory=new JB,this.viewFactory=new qU,this.namedDataProviders=[],this.animator=new uU(()=>this.renderAll()),this.genomeStore=void 0,this.viewVisibilityPredicate=a=>a.isVisibleInSpec(),this._renderingContext=void 0,this._pickingContext=void 0,this._dirtyPickingBuffer=!1,this._currentHover=void 0,this._wheelInertia=new yU(this.animator),this._keyboardListeners=new Map,this._eventListeners=new Map,this._extraBroadcastListeners=new Map,this.tooltipHandlers={default:CU,refseqgene:wU,...r.tooltipHandlers??{}},this.viewRoot=void 0,this._paramBroker=new ZU,this._loadingViews=new Map}registerNamedDataProvider(t){this.namedDataProviders.unshift(t)}getNamedDataFromProvider(t){for(const n of this.namedDataProviders){const r=n(t);if(r)return r}}updateNamedData(t,n){const r=this.viewRoot.context.dataFlow.findNamedDataSource(t);if(!r)throw new Error("No such named data source: "+t);r.dataSource.updateDynamicData(n),Ym(r.hosts),this.animator.requestRender()}broadcast(t,n){var i;const r={type:t,payload:n};this.viewRoot.visit(a=>a.handleBroadcast(r)),(i=this._extraBroadcastListeners.get(t))==null||i.forEach(a=>a(r))}_updateLoadingIndicators(){const t=[],n=()=>[...this._loadingViews.values()].some(r=>r);for(const[r,i]of this._loadingViews){const a=r.coords;if(a){const o={left:`${a.x}px`,top:`${a.y}px`,width:`${a.width}px`,height:`${a.height}px`};t.push($`<div style=${eh(o)}>
|
|
1741
|
+
`:"";return $`${s}${a}`}class Ka extends Yn{constructor(n,r,i,a,o,s){super(n,r,i,a,o,s);Z(this,si,[]);this.spec=n,this.needsAxes={x:!0,y:!0}}async initializeChildren(){le(this,si,await Promise.all(this.spec.layer.map((n,r)=>this.context.createOrImportView(n,this,this,"grid"+r,i=>{if(!od(i)&&!ad(i))throw new Za("LayerView accepts only unit or layer specs as children!",this)}))))}get children(){return F(this,si).slice()}*[Symbol.iterator](){for(const n of F(this,si))yield n}render(n,r,i={}){if(super.render(n,r,i),!!this.isConfiguredVisible()){n.pushView(this,r);for(const a of F(this,si))a.render(n,r,i);n.popView(this)}}propagateInteractionEvent(n){this.handleInteractionEvent(void 0,n,!0);for(let r=F(this,si).length-1;r>=0;r--)if(F(this,si)[r].propagateInteractionEvent(n),n.stopped)return;this.handleInteractionEvent(void 0,n,!1)}}si=new WeakMap;class UE{constructor(t,n){this.n=t,this.maxCols=n??1/0}get nRows(){return this.maxCols==1/0?1:Math.ceil(this.n/this.maxCols)}get nCols(){return Math.min(this.n,this.maxCols)}get rowIndices(){const t=[],n=this.nCols,r=this.nRows;for(let i=0;i<r;i++){const a=[];t.push(a);for(let o=0;o<n;o++){const s=i*n+o;s<this.n&&a.push(s)}}return t}get colIndices(){const t=[],n=this.nCols,r=this.nRows;for(let i=0;i<n;i++){const a=[];t.push(a);for(let o=0;o<r;o++){const s=o*n+i;s<this.n&&a.push(s)}}return t}getCellIndex(t,n){let r=0;if(this.maxCols==1/0)r=n==0?t:void 0;else{if(t>=this.maxCols)return;r=n*this.nCols+t}return r<this.n?r:void 0}getCellCoords(t){if(!(t<0||t>=this.n))return[t%this.nCols,Math.floor(t/this.nCols)]}}const TU="chromosome_ticks_and_labels",IU={x:"width",y:"height"};function e1(e){return e=="x"?"y":"x"}const id={x:["bottom","top"],y:["left","right"]},t1=Object.fromEntries(Object.entries(id).map(([e,t])=>t.map(n=>[n,e])).flat(1));function Ni(e){return t1[e]}class n1 extends Ka{constructor(t,n,r,i,a,o){const s=n=="locus",c={...s?DU:$E,...RU(n,t),...t};super(s?BU(c,n):HE(c,n),r,i,a,`axis_${t.orient}`,{blockEncodingInheritance:!0,contributesToScaleDomain:!1,...o}),this.axisProps=c}getSize(){const t={px:this.getPerpendicularSize()},n={grow:1};return t1[this.axisProps.orient]=="x"?new Gr(n,t):new Gr(t,n)}getPerpendicularSize(){return r1(this.axisProps)}isPickingSupported(){return!1}}function r1(e){const t=Ni(e.orient);let n=e.ticks&&e.tickSize||0;return e.labels&&(n+=e.labelPadding,t=="x"?n+=e.labelFontSize:n+=30),e.title&&(n+=e.titlePadding+e.titleFontSize),n=Math.min(e.maxExtent||1/0,Math.max(e.minExtent||0,n)),n}const $E={values:null,minExtent:20,maxExtent:1/0,offset:0,domain:!0,domainWidth:1,domainColor:"gray",domainDash:null,domainDashOffset:0,domainCap:"square",ticks:!0,tickSize:5,tickWidth:1,tickColor:"gray",tickDash:null,tickDashOffset:0,tickCap:"square",tickCount:null,tickMinStep:null,labels:!0,labelAlign:"center",labelBaseline:"middle",labelPadding:4,labelFontSize:10,labelLimit:180,labelColor:"black",format:null,titleColor:"black",titleFont:"sans-serif",titleFontSize:10,titlePadding:3};function RU(e,t){const n=t.orient,r=e=="nominal"||e=="ordinal";let i="center",a="middle",o=t.labelAngle??((n=="top"||n=="bottom")&&r?-90:0);switch(n){case"left":i="right";break;case"right":i="left";break;case"top":case"bottom":Math.abs(o)>30?(i=o>0==(n=="bottom")?"left":"right",a="middle"):a=n=="top"?"alphabetic":"top";break}return{labelAlign:i,labelAngle:o,labelBaseline:a}}function HE(e,t){const n={...e,extent:r1(e)},r=Ni(n.orient),i=e1(r),a=n.orient=="bottom"||n.orient=="right"?1:-1,o=n.orient=="bottom"||n.orient=="left"?1:0,s=()=>({name:"domain",data:{values:[0]},mark:{type:"rule",clip:!1,strokeDash:n.domainDash,strokeCap:n.domainCap,color:n.domainColor,[i]:o,size:n.domainWidth}}),c=()=>({name:"labels",mark:{type:"text",clip:!1,align:n.labelAlign,angle:n.labelAngle,baseline:n.labelBaseline,[i+"Offset"]:(n.tickSize+n.labelPadding)*a,[i]:o,size:n.labelFontSize,color:n.labelColor,minBufferSize:1500},encoding:{[r]:{field:"value",type:t},text:{field:"label"}}}),l=()=>({name:"ticks",mark:{type:"rule",clip:!1,strokeDash:n.tickDash,strokeCap:n.tickCap,color:n.tickColor,size:n.tickWidth,minBufferSize:300},encoding:{[i]:{value:o},[i+"2"]:{value:o-n.tickSize/n.extent*(o?1:-1)}}}),u=()=>({name:"title",data:{values:[0]},mark:{type:"text",clip:!1,align:"center",baseline:n.orient=="bottom"?"bottom":"top",angle:[0,90,0,-90][["top","right","bottom","left"].indexOf(n.orient)],text:n.title,color:n.titleColor,[r]:.5,[i]:1-o}}),f=()=>{const d={name:"ticks_and_labels",encoding:{[r]:{field:"value",type:t}},layer:[]};return n.ticks&&d.layer.push(l()),n.labels&&d.layer.push(c()),d},h={resolve:{scale:{[r]:"forced"}},[IU[e1(r)]]:n.extent,data:{lazy:{type:"axisTicks",channel:r,axis:e}},layer:[]};return n.domain&&h.layer.push(s()),(n.ticks||n.labels)&&h.layer.push(f()),n.title&&h.layer.push(u()),h}const DU={...$E,chromTicks:!0,chromTickSize:18,chromTickWidth:1,chromTickColor:"#989898",chromTickDash:[4,2],chromTickDashOffset:1,chromLabels:!0,chromLabelFontSize:13,chromLabelFontWeight:"normal",chromLabelFontStyle:"normal",chromLabelColor:"black",chromLabelAlign:"left",chromLabelPadding:7};function BU(e,t){const n={...e,extent:r1(e)},r=Ni(n.orient),i=e1(r),a=n.orient=="bottom"||n.orient=="left"?1:0,o=()=>({name:"chromosome_ticks",mark:{type:"rule",strokeDash:e.chromTickDash,strokeDashOffset:e.chromTickDashOffset,[i]:a,[i+"2"]:a-n.chromTickSize/n.extent*(a?1:-1),color:e.chromTickColor,size:n.chromTickWidth}}),s=()=>{let 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c={...n=="locus"?PU:GE,...t};super(NU(c,n),r,i,a,`axisGrid_${t.orient}`,{blockEncodingInheritance:!0,contributesToScaleDomain:!1,...o}),this.axisProps=c}getOrient(){return this.axisProps.orient}isPickingSupported(){return!1}}const GE={values:null,grid:!1,gridCap:"butt",gridColor:"lightgray",gridDash:null,gridOpacity:1,gridWidth:1,tickCount:null,tickMinStep:null},PU={...GE,chromGrid:!1,chromGridCap:"butt",chromGridColor:"gray",chromGridDash:[1,5],chromGridOpacity:1,chromGridWidth:1};function MU(e,t){const n=e,r=Ni(n.orient);return{name:"grid_lines",data:{lazy:{type:"axisTicks",channel:r,axis:e}},mark:{type:"rule",strokeDash:n.gridDash,strokeCap:n.gridCap,color:n.gridColor,size:n.gridWidth,opacity:n.gridOpacity,minBufferSize:300},encoding:{[r]:{field:"value",type:t}}}}function OU(e,t){const 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WE(e){if(!(!e||!e.stroke||e.strokeWidth===0||e.strokeOpacity===0))return{configurableVisibility:!1,resolve:{scale:{x:"excluded",y:"excluded"},axis:{x:"excluded",y:"excluded"}},data:{values:[{x:0,y:0,x2:1,y2:0},{x:1,y:0,x2:1,y2:1},{x:1,y:1,x2:0,y2:1},{x:0,y:1,x2:0,y2:0}]},mark:{size:e.strokeWidth??1,color:e.stroke??"lightgray",strokeCap:"square",strokeOpacity:e.strokeOpacity??1,type:"rule",clip:!1,tooltip:null},encoding:{x:{field:"x",type:"quantitative",scale:null},y:{field:"y",type:"quantitative",scale:null},x2:{field:"x2"},y2:{field:"y2"}}}}function jU(e){const t={x:new Set,y:new Set};return e.visit(n=>{for(const[r,i]of Object.entries(t)){const a=n.getScaleResolution(r);a&&a.isZoomable()&&i.add(a)}}),t}function qU(e){let t=!0;return e.visit(n=>{n instanceof mt&&t&&(t=n.mark.properties.clip===!0)}),t}function i1(e,t,n){const r=n.axisProps,i=n.getPerpendicularSize();if(t=="bottom")return e.translate(0,e.height+r.offset).modify({height:i});if(t=="top")return e.translate(0,-i-r.offset).modify({height:i});if(t=="left")return e.translate(-i-r.offset,0).modify({width:i});if(t=="right")return e.translate(e.width+r.offset,0).modify({width:i})}class a1{constructor(t,n,r){if(this.layoutParent=n,this.view=t,this.serial=r,this.background=void 0,this.backgroundStroke=void 0,this.axes={},this.gridLines={},this.scrollbars={},this.title=void 0,this.coords=Zn.ZERO,t.needsAxes.x||t.needsAxes.y){const i=t.spec,a="view"in i?i==null?void 0:i.view:void 0,o=qE(a);o&&(this.background=new mt(o,n.context,n,t,"background"+r,{blockEncodingInheritance:!0}));const s=WE(a);s&&(this.backgroundStroke=new mt(s,n.context,n,t,"backgroundStroke"+r,{blockEncodingInheritance:!0}));const c=GU(t.spec.title);if(c){const l=new mt(c,n.context,n,t,"title"+r,{blockEncodingInheritance:!0});this.title=l}}t.spec.viewportWidth!=null&&(this.scrollbars.horizontal=new YE(this,"horizontal")),t.spec.viewportHeight!=null&&(this.scrollbars.vertical=new YE(this,"vertical"))}*getChildren(){this.background&&(yield this.background),this.backgroundStroke&&(yield this.backgroundStroke),this.title&&(yield this.title),yield*Object.values(this.axes),yield*Object.values(this.gridLines),yield this.view,yield*Object.values(this.scrollbars)}async createAxes(){const{view:t,axes:n,gridLines:r}=this,i=(s,c)=>{const l=s.getAxisProps();if(l===null)return;const u=l?{...l}:{};if(!u.orient){for(const f of id[c])if(!n[f]){u.orient=f;break}if(!u.orient)throw new Error("No slots available for an axis! Perhaps a LayerView has more than two children?")}if(u.title??(u.title=s.getTitle()),!id[c].includes(u.orient))throw new Error(`Invalid axis orientation "${u.orient}" on channel "${c}"!`);return u},a=async(s,c,l)=>{const u=i(s,c);if(u){if(n[u.orient])throw new Error(`An axis with the orient "${u.orient}" already exists!`);const f=new n1(u,s.scaleResolution.type,this.layoutParent.context,this.layoutParent,l);n[u.orient]=f,await f.initializeChildren()}},o=async(s,c,l)=>{const u=i(s,c);if(u&&(u.grid||u.chromGrid)){const f=new FU(u,s.scaleResolution.type,this.layoutParent.context,this.layoutParent,l);r[u.orient]=f,await f.initializeChildren()}};for(const s of["x","y"])if(t.needsAxes[s]){const c=t.resolutions.axis[s];if(!c)continue;await a(c,s,t)}for(const s of["x","y"])if(t.needsAxes[s]){const c=t.getAxisResolution(s);if(!c)continue;await o(c,s,t)}if(t instanceof Ka){for(const s of t)for(const[c,l]of Object.entries(s.resolutions.axis)){const u=l.getAxisProps();u&&u.orient&&await a(l,c,s)}for(const s of t)for(const[c,l]of Object.entries(s.resolutions.axis)){const u=l.getAxisProps();u&&!u.orient&&await a(l,c,s)}}[...Object.values(n),...Object.values(r)].forEach(s=>s.visit(c=>{c instanceof mt&&c.resolve("scale")}))}getOverhang(){const t=n=>{const r=this.axes[n];return r?Math.max(r.getPerpendicularSize()+r.axisProps.offset,0):0};return new Ct(t("top"),t("right"),t("bottom"),t("left")).add(this.view.getOverhang())}getOverhangAndPadding(){return this.getOverhang().add(this.view.getPadding())}}class YE extends mt{constructor(t,n){const r={scrollbarSize:8,scrollbarPadding:2};super({data:{values:[{}]},mark:{type:"rect",fill:"#b0b0b0",fillOpacity:.6,stroke:"white",strokeWidth:1,strokeOpacity:1,cornerRadius:5,clip:!1},configurableVisibility:!1},t.layoutParent.context,t.layoutParent,t.view,"scrollbar-"+n,{blockEncodingInheritance:!0}),this.config=r,this.scrollDirection=n,this.viewportOffset=0,this.maxScrollOffset=0,this.scrollbarCoords=Zn.ZERO,this.addInteractionEventListener("mousedown",(i,a)=>{if(a.stopPropagation(),this.maxScrollOffset<=0)return;const o=h=>n=="vertical"?h.clientY:h.clientX,s=a.uiEvent;s.preventDefault();const c=this.getScrollOffset(),l=o(s),u=h=>{const d=Ai(o(h)-l+c,0,this.maxScrollOffset);this.viewportOffset=d/this.maxScrollOffset*this.maxViewportOffset,this.context.animator.requestRender()},f=()=>{document.removeEventListener("mousemove",u),document.removeEventListener("mouseup",f)};document.addEventListener("mouseup",f,!1),document.addEventListener("mousemove",u,!1)})}getScrollOffset(){return this.viewportOffset/this.maxViewportOffset*this.maxScrollOffset}render(t,n,r){super.render(t,this.scrollbarCoords,r)}updateScrollbar(t,n){const r=this.config.scrollbarPadding,i=this.config.scrollbarSize,a=this.scrollDirection=="horizontal"?"width":"height",o=Math.min(1,t[a]/n[a]),s=t[a]-2*r,c=o*s;this.maxScrollOffset=s-c,this.maxViewportOffset=n[a]-t[a],this.viewportOffset=Ai(this.viewportOffset,0,this.maxViewportOffset),this.scrollbarCoords=this.scrollDirection=="vertical"?new Zn(()=>t.x+t.width-i-r,()=>t.y+r+this.getScrollOffset(),()=>i,()=>c):new Zn(()=>t.x+r+this.getScrollOffset(),()=>t.y+t.height-i-r,()=>c,()=>i)}}class ys extends VU{constructor(t,n,r,i,a){super(t,n,r,i,a,o1(t)?t.columns:sd(t)?1:1/0),this.spec=t}async initializeChildren(){const t=this.spec,n=o1(t)?t.concat:sd(t)?t.vconcat:t.hconcat;this.setChildren(await Promise.all(n.map((r,i)=>this.context.createOrImportView(r,this,this,"grid"+i)))),await this.createAxes()}getDefaultResolution(t,n){return n=="axis"?"independent":sd(this.spec)&&t==="x"||QE(this.spec)&&t==="y"?"shared":"independent"}}const ZE="viewRoot";class WU{constructor(t={}){Z(this,vc,new Map);this.options={allowImport:!0,wrapRoot:!0,...t};const n=r=>(i,a,o,s,c)=>new r(i,a,o,s,i.name??c);this.addViewType(od,n(Ka)),this.addViewType(ad,n(mt)),this.addViewType(sd,n(ys)),this.addViewType(QE,n(ys)),this.addViewType(o1,n(ys)),this.addViewType(XE,()=>{throw new Error("SampleView is not supported by the @genome-spy/core package. Use @genome-spy/app instead!")})}addViewType(t,n){F(this,vc).set(t,n)}createView(t,n,r,i,a){for(const[o,s]of F(this,vc))if(o(t))return s(t,n,r,i,a);throw new Error("Invalid spec, cannot figure out the view type from the properties: "+JSON.stringify([...Object.keys(t)]))}isViewSpec(t){const n=[...F(this,vc).keys()].filter(r=>r(t));if(n.length>1)throw new Error("Ambiguous spec. Cannot create a view!");return n.length==1}async createOrImportView(t,n,r,i,a,o){let s;if(ZU(t))if(this.options.allowImport)s=await iU(t,i.getBaseUrl(),n),o&&o(s);else throw new Za("Importing views is not allowed!",r);else s=t;!i&&this.options.wrapRoot&&(ad(s)||od(s))&&a===ZE&&(s={name:"implicitRoot",vconcat:[s]});const c=this.createView(s,n,r,i,a);return c instanceof Yn&&await c.initializeChildren(),c}}vc=new WeakMap;function ad(e){return"mark"in e&&(Me(e.mark)||Xt(e.mark))}function od(e){return"layer"in e&&Xt(e.layer)}function YU(e){return e&&(ad(e)||od(e))&&"aggregateSamples"in e}function ZU(e){return"import"in e}function sd(e){return"vconcat"in e&&Qt(e.vconcat)}function QE(e){return"hconcat"in e&&Qt(e.hconcat)}function o1(e){return"concat"in e&&Qt(e.concat)}function XE(e){return"samples"in e&&Xt(e.samples)&&"spec"in e&&Xt(e.spec)}class QU{constructor(){Z(this,wc,void 0);Z(this,No,void 0);Z(this,yf,void 0);Z(this,zo,void 0);le(this,wc,new Map),le(this,No,new Set),le(this,zo,new Map),le(this,yf,new Proxy(F(this,wc),{get(t,n){return Me(n)?t.get(n):void 0}}))}allocateSetter(t){if(F(this,No).has(t))throw new Error("Setter already allocated for parameter: "+t);return F(this,No).add(t),n=>{F(this,wc).set(t,n);const r=F(this,zo).get(t);if(r)for(const i of r)i()}}createExpression(t){const n=ch(t,F(this,yf));for(const r of n.globals)if(!F(this,No).has(r))throw new Error(`Unknown variable "${r}" in expression: ${t}`);return n.addListener=r=>{for(const i of n.globals){const a=F(this,zo).get(i)??new Set;F(this,zo).set(i,a),a.add(r)}},n}}wc=new WeakMap,No=new WeakMap,yf=new WeakMap,zo=new WeakMap,hw("fasta",yU);class KE{constructor(t,n,r={}){this.container=t,this._destructionCallbacks=[];const i=document.createElement("style");i.innerHTML=fD,t.appendChild(i),this.spec=n,this.accessorFactory=new JB,this.viewFactory=new WU,this.namedDataProviders=[],this.animator=new fU(()=>this.renderAll()),this.genomeStore=void 0,this.viewVisibilityPredicate=a=>a.isVisibleInSpec(),this._renderingContext=void 0,this._pickingContext=void 0,this._dirtyPickingBuffer=!1,this._currentHover=void 0,this._wheelInertia=new vU(this.animator),this._keyboardListeners=new Map,this._eventListeners=new Map,this._extraBroadcastListeners=new Map,this.tooltipHandlers={default:kU,refseqgene:xU,...r.tooltipHandlers??{}},this.viewRoot=void 0,this._paramBroker=new QU,this._loadingViews=new Map}registerNamedDataProvider(t){this.namedDataProviders.unshift(t)}getNamedDataFromProvider(t){for(const n of this.namedDataProviders){const r=n(t);if(r)return r}}updateNamedData(t,n){const r=this.viewRoot.context.dataFlow.findNamedDataSource(t);if(!r)throw new Error("No such named data source: "+t);r.dataSource.updateDynamicData(n),Ym(r.hosts),this.animator.requestRender()}broadcast(t,n){var i;const r={type:t,payload:n};this.viewRoot.visit(a=>a.handleBroadcast(r)),(i=this._extraBroadcastListeners.get(t))==null||i.forEach(a=>a(r))}_updateLoadingIndicators(){const t=[],n=()=>[...this._loadingViews.values()].some(r=>r);for(const[r,i]of this._loadingViews){const a=r.coords;if(a){const o={left:`${a.x}px`,top:`${a.y}px`,width:`${a.width}px`,height:`${a.height}px`};t.push($`<div style=${eh(o)}>
|
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1739
1742
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<div class=${i?"loading":""}>
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1740
1743
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<img src="${uD}" alt="" />
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1741
1744
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<span>Loading...</span>
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1742
1745
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</div>
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1743
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-
</div>`)}}n()?this.loadingIndicatorsElement.style.display="block":setTimeout(()=>{n()||(this.loadingIndicatorsElement.style.display="none")},3e3),Vt(t,this.loadingIndicatorsElement)}_prepareContainer(){this.container.classList.add("genome-spy"),this.container.classList.add("loading"),this._glHelper=new mL(this.container,()=>this.viewRoot?aU(this.viewRoot):{width:void 0,height:void 0},this.spec.background);const t=()=>{this._glHelper.invalidateSize(),r(window.devicePixelRatio),this.computeLayout(),this.renderAll()},n=new ResizeObserver(t);n.observe(this.container),this._destructionCallbacks.push(()=>n.disconnect());const r=this._paramBroker.allocateSetter("devicePixelRatio");r(window.devicePixelRatio);let i=null;const a=()=>{i!=null&&(i(),t());const o=matchMedia(`(resolution: ${window.devicePixelRatio}dppx)`);o.addEventListener("change",a),i=()=>{o.removeEventListener("change",a)}};a(),i&&this._destructionCallbacks.push(i),this.loadingMessageElement=document.createElement("div"),this.loadingMessageElement.className="loading-message",this.loadingMessageElement.innerHTML='<div class="message">Loading<span class="ellipsis">...</span></div>',this.container.appendChild(this.loadingMessageElement),this.loadingIndicatorsElement=document.createElement("div"),this.loadingIndicatorsElement.className="loading-indicators",this.container.appendChild(this.loadingIndicatorsElement),this.tooltip=new hD(this.container),this.loadingMessageElement.querySelector(".message").addEventListener("transitionend",()=>{this.loadingMessageElement.style.display="none"})}destroy(){this.container.classList.remove("genome-spy"),this.container.classList.remove("loading");for(const[t,n]of this._keyboardListeners)for(const r of n)document.removeEventListener(t,r);for(this._destructionCallbacks.forEach(t=>t()),this._glHelper.finalize();this.container.firstChild;)this.container.firstChild.remove()}async _prepareViewsAndData(){this.spec.genome&&(this.genomeStore=new fU(this.spec.baseUrl),await this.genomeStore.initialize(this.spec.genome));const t=this,n={dataFlow:new TE,accessorFactory:this.accessorFactory,glHelper:this._glHelper,animator:this.animator,genomeStore:this.genomeStore,fontManager:new pU(this._glHelper),get devicePixelRatio(){return t._glHelper.dpr},paramBroker:this._paramBroker,requestLayoutReflow:()=>{},updateTooltip:this.updateTooltip.bind(this),getNamedDataFromProvider:this.getNamedDataFromProvider.bind(this),getCurrentHover:()=>this._currentHover,setDataLoadingStatus:(c,l)=>{this._loadingViews.set(c,l),this._updateLoadingIndicators()},addKeyboardListener:(c,l)=>{document.addEventListener(c,l);let u=this._keyboardListeners.get(c);u||(u=[],this._keyboardListeners.set(c,u)),u.push(l)},addBroadcastListener(c,l){const u=t._extraBroadcastListeners;let f=u.get(c);f||(f=new Set,u.set(c,f)),f.add(l)},removeBroadcastListener(c,l){var f;(f=t._extraBroadcastListeners.get(c))==null||f.delete(l)},isViewConfiguredVisible:t.viewVisibilityPredicate,isViewSpec:c=>t.viewFactory.isViewSpec(c),createView:function(c,l,u,f){return t.viewFactory.createView(c,n,l,u,f)},createOrImportView:async function(c,l,u,f,h){return t.viewFactory.createOrImportView(c,n,l,u,f,h)}},r=this.spec;r.datasets&&this.registerNamedDataProvider(c=>r.datasets[c]),this.viewRoot=await n.createOrImportView(r,null,null,ZE),PE(this.viewRoot),tU(this.viewRoot);const i=this.viewRoot.getDescendants();i.forEach(c=>c.configureViewOpacity()),this._glHelper.invalidateSize();const a=i.filter(c=>c instanceof mt),o=BE(this.viewRoot,n.dataFlow);eU(o),this.broadcast("dataFlowBuilt",o),a.forEach(c=>c.mark.initializeEncoders());const s=Promise.all(a.map(c=>c.mark.initializeGraphics()));for(const c of a)o.addObserver(l=>{c.mark.initializeData(),c.mark.updateGraphicsData()},c);await n.fontManager.waitUntilReady(),o.initialize(),await Promise.all(o.dataSources.map(c=>c.load())),Ym(this.viewRoot),this.broadcast("dataLoaded"),await s,this.viewRoot.visit(c=>{for(const l of Object.values(c.resolutions.scale))this._glHelper.createRangeTexture(l)});for(const c of a)c.mark.finalizeGraphicsInitialization();n.requestLayoutReflow=this.computeLayout.bind(this),this.viewRoot.visit(c=>Il(c,"size")),this._glHelper.invalidateSize()}async launch(){try{return this._prepareContainer(),await this._prepareViewsAndData(),this.registerMouseEvents(),this.computeLayout(),this.animator.requestRender(),!0}catch(t){const n=`${t.view?`At "${t.view.getPathString()}": `:""}${t.toString()}`;return console.error(t.stack),QU(this.container,n),!1}finally{this.container.classList.remove("loading"),window.setTimeout(()=>{this.loadingMessageElement.style.display="none"},2e3)}}registerMouseEvents(){const t=this._glHelper.canvas,n=r=>{var i;if(r instanceof MouseEvent){r.type=="mousemove"&&(this.tooltip.handleMouseMove(r),this._tooltipUpdateRequested=!1,r.buttons==0&&this.renderPickingFramebuffer());const a=t.getBoundingClientRect(),o=new cU(r.clientX-a.left-t.clientLeft,r.clientY-a.top-t.clientTop),s=c=>{this.viewRoot.propagateInteractionEvent(new sU(o,c)),this._tooltipUpdateRequested||this.tooltip.clear()};if(r.type!="wheel"&&this._wheelInertia.cancel(),r.type=="mousemove")this._handlePicking(o.x,o.y);else if(r.type=="mousedown"||r.type=="mouseup")this.renderPickingFramebuffer();else if(r.type=="wheel"){this._tooltipUpdateRequested=!1;const c=r;if(Math.abs(c.deltaX)>Math.abs(c.deltaY))this._currentHover=null,this._wheelInertia.cancel();else{const l=vU(c);this._wheelInertia.setMomentum(c.deltaY*(c.deltaMode?80:1),u=>{const f=new WheelEvent("wheel",{...l,deltaMode:0,deltaX:0,deltaY:u});s(f)}),c.preventDefault();return}}if(r.type=="click"){const c=this._currentHover?{type:r.type,viewPath:this._currentHover.mark.unitView.getLayoutAncestors().map(l=>l.name).reverse(),datum:this._currentHover.datum}:{type:r.type,viewPath:null,datum:null};(i=this._eventListeners.get("click"))==null||i.forEach(l=>l(c))}s(r)}};["mousedown","mouseup","wheel","click","mousemove","gesturechange","contextmenu"].forEach(r=>t.addEventListener(r,n)),t.addEventListener("mousedown",()=>{document.addEventListener("mouseup",()=>this.tooltip.popEnabledState(),{once:!0}),this.tooltip.pushEnabledState(!1)}),t.addEventListener("dragstart",r=>r.stopPropagation())}_handlePicking(t,n){var a;const r=this._glHelper.readPickingPixel(t,n),i=r[0]|r[1]<<8|r[2]<<16;if(i==0){this._currentHover=null;return}if(i!==((a=this._currentHover)==null?void 0:a.uniqueId)&&(this._currentHover=null),this._currentHover||this.viewRoot.visit(o=>{if(o instanceof mt){if(o.mark.isPickingParticipant()){const s=o.mark.encoders.uniqueId.accessor;o.getCollector().visitData(c=>{s(c)==i&&(this._currentHover={mark:o.mark,datum:c,uniqueId:i})})}if(this._currentHover)return Qa}}),this._currentHover){const o=this._currentHover.mark;this.updateTooltip(this._currentHover.datum,async s=>{if(!o.isPickingParticipant())return;const c=o.properties.tooltip;if(c!==null){const l=(c==null?void 0:c.handler)??"default",u=this.tooltipHandlers[l];if(!u)throw new Error("No such tooltip handler: "+l);return u(s,o,c==null?void 0:c.params)}})}}updateTooltip(t,n){if(!this._tooltipUpdateRequested||!t)this.tooltip.updateWithDatum(t,n),this._tooltipUpdateRequested=!0;else throw new Error("Tooltip has already been updated! Duplicate event handler?")}computeLayout(){const t=this.viewRoot;if(!t)return;this.broadcast("layout");const n=this._glHelper.getLogicalCanvasSize();if(isNaN(n.width)||isNaN(n.height)){console.log(`NaN in canvas size: ${n.width}x${n.height}. Skipping computeLayout().`);return}this._renderingContext=new LE({picking:!1},this._glHelper),this._pickingContext=new LE({picking:!0},this._glHelper),t.render(new oU(this._renderingContext,this._pickingContext),Zn.create(0,0,n.width,n.height)),this.broadcast("layoutComputed")}renderAll(){var t;(t=this._renderingContext)==null||t.render(),this._dirtyPickingBuffer=!0}renderPickingFramebuffer(){this._dirtyPickingBuffer&&(this._pickingContext.render(),this._dirtyPickingBuffer=!1)}getSearchableViews(){const t=[];return this.viewRoot.visit(n=>{n instanceof mt&&n.getAccessor("search")&&t.push(n)}),t}getNamedScaleResolutions(){const t=new Map;return this.viewRoot.visit(n=>{for(const r of Object.values(n.resolutions.scale))r.name&&t.set(r.name,r)}),t}}function QU(e,t){const n=document.createElement("div");n.className="message-box";const r=document.createElement("div");r.textContent=t,n.appendChild(r),e.appendChild(n)}const 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|
|
1746
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+
</div>`)}}n()?this.loadingIndicatorsElement.style.display="block":setTimeout(()=>{n()||(this.loadingIndicatorsElement.style.display="none")},3e3),Vt(t,this.loadingIndicatorsElement)}_prepareContainer(){this.container.classList.add("genome-spy"),this.container.classList.add("loading"),this._glHelper=new mL(this.container,()=>this.viewRoot?oU(this.viewRoot):{width:void 0,height:void 0},this.spec.background);const t=()=>{this._glHelper.invalidateSize(),r(window.devicePixelRatio),this.computeLayout(),this.renderAll()},n=new ResizeObserver(t);n.observe(this.container),this._destructionCallbacks.push(()=>n.disconnect());const r=this._paramBroker.allocateSetter("devicePixelRatio");r(window.devicePixelRatio);let i=null;const a=()=>{i!=null&&(i(),t());const o=matchMedia(`(resolution: 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n)document.removeEventListener(t,r);for(this._destructionCallbacks.forEach(t=>t()),this._glHelper.finalize();this.container.firstChild;)this.container.firstChild.remove()}async _prepareViewsAndData(){this.spec.genome&&(this.genomeStore=new hU(this.spec.baseUrl),await this.genomeStore.initialize(this.spec.genome));const t=this,n={dataFlow:new TE,accessorFactory:this.accessorFactory,glHelper:this._glHelper,animator:this.animator,genomeStore:this.genomeStore,fontManager:new gU(this._glHelper),get devicePixelRatio(){return t._glHelper.dpr},paramBroker:this._paramBroker,requestLayoutReflow:()=>{},updateTooltip:this.updateTooltip.bind(this),getNamedDataFromProvider:this.getNamedDataFromProvider.bind(this),getCurrentHover:()=>this._currentHover,setDataLoadingStatus:(c,l)=>{this._loadingViews.set(c,l),this._updateLoadingIndicators()},addKeyboardListener:(c,l)=>{document.addEventListener(c,l);let u=this._keyboardListeners.get(c);u||(u=[],this._keyboardListeners.set(c,u)),u.push(l)},addBroadcastListener(c,l){const u=t._extraBroadcastListeners;let f=u.get(c);f||(f=new Set,u.set(c,f)),f.add(l)},removeBroadcastListener(c,l){var f;(f=t._extraBroadcastListeners.get(c))==null||f.delete(l)},isViewConfiguredVisible:t.viewVisibilityPredicate,isViewSpec:c=>t.viewFactory.isViewSpec(c),createView:function(c,l,u,f){return t.viewFactory.createView(c,n,l,u,f)},createOrImportView:async function(c,l,u,f,h){return t.viewFactory.createOrImportView(c,n,l,u,f,h)}},r=this.spec;r.datasets&&this.registerNamedDataProvider(c=>r.datasets[c]),this.viewRoot=await n.createOrImportView(r,null,null,ZE),PE(this.viewRoot),nU(this.viewRoot);const i=this.viewRoot.getDescendants();i.forEach(c=>c.configureViewOpacity()),this._glHelper.invalidateSize();const a=i.filter(c=>c instanceof mt),o=BE(this.viewRoot,n.dataFlow);tU(o),this.broadcast("dataFlowBuilt",o),a.forEach(c=>c.mark.initializeEncoders());const s=Promise.all(a.map(c=>c.mark.initializeGraphics()));for(const c of a)o.addObserver(l=>{c.mark.initializeData(),c.mark.updateGraphicsData()},c);await n.fontManager.waitUntilReady(),o.initialize(),await Promise.all(o.dataSources.map(c=>c.load())),Ym(this.viewRoot),this.broadcast("dataLoaded"),await s,this.viewRoot.visit(c=>{for(const l of Object.values(c.resolutions.scale))this._glHelper.createRangeTexture(l)});for(const c of a)c.mark.finalizeGraphicsInitialization();n.requestLayoutReflow=this.computeLayout.bind(this),this.viewRoot.visit(c=>Il(c,"size")),this._glHelper.invalidateSize()}async launch(){try{return this._prepareContainer(),await this._prepareViewsAndData(),this.registerMouseEvents(),this.computeLayout(),this.animator.requestRender(),!0}catch(t){const n=`${t.view?`At "${t.view.getPathString()}": `:""}${t.toString()}`;return console.error(t.stack),XU(this.container,n),!1}finally{this.container.classList.remove("loading"),window.setTimeout(()=>{this.loadingMessageElement.style.display="none"},2e3)}}registerMouseEvents(){const t=this._glHelper.canvas,n=r=>{var i;if(r instanceof MouseEvent){r.type=="mousemove"&&(this.tooltip.handleMouseMove(r),this._tooltipUpdateRequested=!1,r.buttons==0&&this.renderPickingFramebuffer());const a=t.getBoundingClientRect(),o=new lU(r.clientX-a.left-t.clientLeft,r.clientY-a.top-t.clientTop),s=c=>{this.viewRoot.propagateInteractionEvent(new cU(o,c)),this._tooltipUpdateRequested||this.tooltip.clear()};if(r.type!="wheel"&&this._wheelInertia.cancel(),r.type=="mousemove")this._handlePicking(o.x,o.y);else if(r.type=="mousedown"||r.type=="mouseup")this.renderPickingFramebuffer();else if(r.type=="wheel"){this._tooltipUpdateRequested=!1;const c=r;if(Math.abs(c.deltaX)>Math.abs(c.deltaY))this._currentHover=null,this._wheelInertia.cancel();else{const l=wU(c);this._wheelInertia.setMomentum(c.deltaY*(c.deltaMode?80:1),u=>{const f=new WheelEvent("wheel",{...l,deltaMode:0,deltaX:0,deltaY:u});s(f)}),c.preventDefault();return}}if(r.type=="click"){const c=this._currentHover?{type:r.type,viewPath:this._currentHover.mark.unitView.getLayoutAncestors().map(l=>l.name).reverse(),datum:this._currentHover.datum}:{type:r.type,viewPath:null,datum:null};(i=this._eventListeners.get("click"))==null||i.forEach(l=>l(c))}s(r)}};["mousedown","mouseup","wheel","click","mousemove","gesturechange","contextmenu"].forEach(r=>t.addEventListener(r,n)),t.addEventListener("mousedown",()=>{document.addEventListener("mouseup",()=>this.tooltip.popEnabledState(),{once:!0}),this.tooltip.pushEnabledState(!1)}),t.addEventListener("dragstart",r=>r.stopPropagation())}_handlePicking(t,n){var a;const r=this._glHelper.readPickingPixel(t,n),i=r[0]|r[1]<<8|r[2]<<16;if(i==0){this._currentHover=null;return}if(i!==((a=this._currentHover)==null?void 0:a.uniqueId)&&(this._currentHover=null),this._currentHover||this.viewRoot.visit(o=>{if(o instanceof mt){if(o.mark.isPickingParticipant()){const s=o.mark.encoders.uniqueId.accessor;o.getCollector().visitData(c=>{s(c)==i&&(this._currentHover={mark:o.mark,datum:c,uniqueId:i})})}if(this._currentHover)return Qa}}),this._currentHover){const o=this._currentHover.mark;this.updateTooltip(this._currentHover.datum,async s=>{if(!o.isPickingParticipant())return;const c=o.properties.tooltip;if(c!==null){const l=(c==null?void 0:c.handler)??"default",u=this.tooltipHandlers[l];if(!u)throw new Error("No such tooltip handler: "+l);return u(s,o,c==null?void 0:c.params)}})}}updateTooltip(t,n){if(!this._tooltipUpdateRequested||!t)this.tooltip.updateWithDatum(t,n),this._tooltipUpdateRequested=!0;else throw new Error("Tooltip has already been updated! Duplicate event handler?")}computeLayout(){const t=this.viewRoot;if(!t)return;this.broadcast("layout");const n=this._glHelper.getLogicalCanvasSize();if(isNaN(n.width)||isNaN(n.height)){console.log(`NaN in canvas size: ${n.width}x${n.height}. 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*/const cd=globalThis,s1=cd.ShadowRoot&&(cd.ShadyCSS===void 0||cd.ShadyCSS.nativeShadow)&&"adoptedStyleSheets"in Document.prototype&&"replace"in CSSStyleSheet.prototype,JE=Symbol(),e4=new WeakMap;let
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*/const cd=globalThis,s1=cd.ShadowRoot&&(cd.ShadyCSS===void 0||cd.ShadyCSS.nativeShadow)&&"adoptedStyleSheets"in Document.prototype&&"replace"in CSSStyleSheet.prototype,JE=Symbol(),e4=new WeakMap;let JU=class{constructor(t,n,r){if(this._$cssResult$=!0,r!==JE)throw Error("CSSResult is not constructable. Use `unsafeCSS` or `css` instead.");this.cssText=t,this.t=n}get styleSheet(){let t=this.o;const n=this.t;if(s1&&t===void 0){const r=n!==void 0&&n.length===1;r&&(t=e4.get(n)),t===void 0&&((this.o=t=new CSSStyleSheet).replaceSync(this.cssText),r&&e4.set(n,t))}return t}toString(){return this.cssText}};const e$=e=>new JU(typeof e=="string"?e:e+"",void 0,JE),t$=(e,t)=>{if(s1)e.adoptedStyleSheets=t.map(n=>n instanceof CSSStyleSheet?n:n.styleSheet);else for(const n of t){const r=document.createElement("style"),i=cd.litNonce;i!==void 0&&r.setAttribute("nonce",i),r.textContent=n.cssText,e.appendChild(r)}},t4=s1?e=>e:e=>e instanceof CSSStyleSheet?(t=>{let n="";for(const r of t.cssRules)n+=r.cssText;return e$(n)})(e):e;/**
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*/const{is:
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*/const{is:n$,defineProperty:r$,getOwnPropertyDescriptor:i$,getOwnPropertyNames:a$,getOwnPropertySymbols:o$,getPrototypeOf:s$}=Object,zi=globalThis,n4=zi.trustedTypes,c$=n4?n4.emptyScript:"",c1=zi.reactiveElementPolyfillSupport,zl=(e,t)=>e,l1={toAttribute(e,t){switch(t){case Boolean:e=e?c$:null;break;case Object:case Array:e=e==null?e:JSON.stringify(e)}return e},fromAttribute(e,t){let n=e;switch(t){case Boolean:n=e!==null;break;case Number:n=e===null?null:Number(e);break;case Object:case Array:try{n=JSON.parse(e)}catch{n=null}}return n}},r4=(e,t)=>!n$(e,t),i4={attribute:!0,type:String,converter:l1,reflect:!1,hasChanged:r4};Symbol.metadata??(Symbol.metadata=Symbol("metadata")),zi.litPropertyMetadata??(zi.litPropertyMetadata=new WeakMap);let vs=class extends HTMLElement{static addInitializer(t){this._$Ei(),(this.l??(this.l=[])).push(t)}static get observedAttributes(){return this.finalize(),this._$Eh&&[...this._$Eh.keys()]}static createProperty(t,n=i4){if(n.state&&(n.attribute=!1),this._$Ei(),this.elementProperties.set(t,n),!n.noAccessor){const r=Symbol(),i=this.getPropertyDescriptor(t,r,n);i!==void 0&&r$(this.prototype,t,i)}}static getPropertyDescriptor(t,n,r){const{get:i,set:a}=i$(this.prototype,t)??{get(){return this[n]},set(o){this[n]=o}};return{get(){return i==null?void 0:i.call(this)},set(o){const s=i==null?void 0:i.call(this);a.call(this,o),this.requestUpdate(t,s,r)},configurable:!0,enumerable:!0}}static getPropertyOptions(t){return this.elementProperties.get(t)??i4}static _$Ei(){if(this.hasOwnProperty(zl("elementProperties")))return;const t=s$(this);t.finalize(),t.l!==void 0&&(this.l=[...t.l]),this.elementProperties=new Map(t.elementProperties)}static finalize(){if(this.hasOwnProperty(zl("finalized")))return;if(this.finalized=!0,this._$Ei(),this.hasOwnProperty(zl("properties"))){const n=this.properties,r=[...a$(n),...o$(n)];for(const i of r)this.createProperty(i,n[i])}const t=this[Symbol.metadata];if(t!==null){const n=litPropertyMetadata.get(t);if(n!==void 0)for(const[r,i]of n)this.elementProperties.set(r,i)}this._$Eh=new Map;for(const[n,r]of this.elementProperties){const i=this._$Eu(n,r);i!==void 0&&this._$Eh.set(i,n)}this.elementStyles=this.finalizeStyles(this.styles)}static finalizeStyles(t){const n=[];if(Array.isArray(t)){const r=new Set(t.flat(1/0).reverse());for(const i of r)n.unshift(t4(i))}else t!==void 0&&n.push(t4(t));return n}static _$Eu(t,n){const r=n.attribute;return r===!1?void 0:typeof r=="string"?r:typeof t=="string"?t.toLowerCase():void 0}constructor(){super(),this._$Ep=void 0,this.isUpdatePending=!1,this.hasUpdated=!1,this._$Em=null,this._$Ev()}_$Ev(){var t;this._$Eg=new Promise(n=>this.enableUpdating=n),this._$AL=new Map,this._$ES(),this.requestUpdate(),(t=this.constructor.l)==null||t.forEach(n=>n(this))}addController(t){var n;(this._$E_??(this._$E_=new Set)).add(t),this.renderRoot!==void 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r;if(!this.isUpdatePending)return;if(!this.hasUpdated){if(this.renderRoot??(this.renderRoot=this.createRenderRoot()),this._$Ep){for(const[a,o]of this._$Ep)this[a]=o;this._$Ep=void 0}const i=this.constructor.elementProperties;if(i.size>0)for(const[a,o]of i)o.wrapped!==!0||this._$AL.has(a)||this[a]===void 0||this.C(a,this[a],o)}let t=!1;const n=this._$AL;try{t=this.shouldUpdate(n),t?(this.willUpdate(n),(r=this._$E_)==null||r.forEach(i=>{var a;return(a=i.hostUpdate)==null?void 0:a.call(i)}),this.update(n)):this._$ET()}catch(i){throw t=!1,this._$ET(),i}t&&this._$AE(n)}willUpdate(t){}_$AE(t){var n;(n=this._$E_)==null||n.forEach(r=>{var i;return(i=r.hostUpdated)==null?void 0:i.call(r)}),this.hasUpdated||(this.hasUpdated=!0,this.firstUpdated(t)),this.updated(t)}_$ET(){this._$AL=new Map,this.isUpdatePending=!1}get updateComplete(){return this.getUpdateComplete()}getUpdateComplete(){return this._$Eg}shouldUpdate(t){return!0}update(t){this._$Ej&&(this._$Ej=this._$Ej.forEach(n=>this._$EO(n,this[n]))),this._$ET()}updated(t){}firstUpdated(t){}};vs.elementStyles=[],vs.shadowRootOptions={mode:"open"},vs[zl("elementProperties")]=new Map,vs[zl("finalized")]=new Map,c1==null||c1({ReactiveElement:vs}),(zi.reactiveElementVersions??(zi.reactiveElementVersions=[])).push("2.0.2");/**
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@@ -1756,9 +1759,9 @@ Reason: ${s.message}`)}));if(n.isViewSpec(a))return a.baseUrl=(o=i.match(/^[^?#]
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|
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1762
1765
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--fa-font-solid: normal 900 1em/1 "Font Awesome 6 Solid";
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1763
1766
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--fa-font-regular: normal 400 1em/1 "Font Awesome 6 Regular";
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1764
1767
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--fa-font-light: normal 300 1em/1 "Font Awesome 6 Light";
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@@ -2514,17 +2517,17 @@ svg:not(:root).svg-inline--fa, svg:not(:host).svg-inline--fa {
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2514
2517
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.fad.fa-inverse,
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2515
2518
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.fa-duotone.fa-inverse {
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2516
2519
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color: var(--fa-inverse, #fff);
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2517
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-
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* @license
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* Copyright 2020 Google LLC
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*/const{D:
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*/const{D:yG}=cD,vG=e=>e===null||typeof e!="object"&&typeof e!="function",cS=e=>e.strings===void 0,lS=()=>document.createComment(""),Kl=(e,t,n)=>{var a;const r=e._$AA.parentNode,i=t===void 0?e._$AB:t._$AA;if(n===void 0){const o=r.insertBefore(lS(),i),s=r.insertBefore(lS(),i);n=new yG(o,s,e,e.options)}else{const o=n._$AB.nextSibling,s=n._$AM,c=s!==e;if(c){let l;(a=n._$AQ)==null||a.call(n,e),n._$AM=e,n._$AP!==void 0&&(l=e._$AU)!==s._$AU&&n._$AP(l)}if(o!==i||c){let l=n._$AA;for(;l!==o;){const u=l.nextSibling;r.insertBefore(l,i),l=u}}}return n},io=(e,t,n=e)=>(e._$AI(t,n),e),wG={},uS=(e,t=wG)=>e._$AH=t,xG=e=>e._$AH,$1=e=>{var r;(r=e._$AP)==null||r.call(e,!1,!0);let t=e._$AA;const n=e._$AB.nextSibling;for(;t!==n;){const i=t.nextSibling;t.remove(),t=i}};/**
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* @license
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* Copyright 2017 Google LLC
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* SPDX-License-Identifier: BSD-3-Clause
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*/const fS=(e,t,n)=>{const r=new Map;for(let i=t;i<=n;i++)r.set(e[i],i);return r},
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*/const fS=(e,t,n)=>{const r=new Map;for(let i=t;i<=n;i++)r.set(e[i],i);return r},AG=Da(class extends Zo{constructor(e){if(super(e),e.type!==cr.CHILD)throw Error("repeat() can only be used in text expressions")}ht(e,t,n){let r;n===void 0?n=t:t!==void 0&&(r=t);const i=[],a=[];let o=0;for(const s of e)i[o]=r?r(s,o):o,a[o]=n(s,o),o++;return{values:a,keys:i}}render(e,t,n){return this.ht(e,t,n).values}update(e,[t,n,r]){const i=xG(e),{values:a,keys:o}=this.ht(t,n,r);if(!Array.isArray(i))return this.dt=o,a;const s=this.dt??(this.dt=[]),c=[];let l,u,f=0,h=i.length-1,d=0,p=a.length-1;for(;f<=h&&d<=p;)if(i[f]===null)f++;else if(i[h]===null)h--;else if(s[f]===o[d])c[d]=io(i[f],a[d]),f++,d++;else if(s[h]===o[p])c[p]=io(i[h],a[p]),h--,p--;else if(s[f]===o[p])c[p]=io(i[f],a[p]),Kl(e,c[p+1],i[f]),f++,p--;else if(s[h]===o[d])c[d]=io(i[h],a[d]),Kl(e,i[f],i[h]),h--,d++;else if(l===void 0&&(l=fS(o,d,p),u=fS(s,f,h)),l.has(s[f]))if(l.has(s[h])){const g=u.get(o[d]),b=g!==void 0?i[g]:null;if(b===null){const y=Kl(e,i[f]);io(y,a[d]),c[d]=y}else c[d]=io(b,a[d]),Kl(e,i[f],b),i[g]=null;d++}else $1(i[h]),h--;else $1(i[f]),f++;for(;d<=p;){const g=Kl(e,c[p+1]);io(g,a[d]),c[d++]=g}for(;f<=h;){const g=i[f++];g!==null&&$1(g)}return this.dt=o,uS(e,c),Dt}}),hS="close-dialog";function EG(){return new CustomEvent(hS,{bubbles:!0})}function ao(e="default",t=document.body){const n=document.createElement("div");n.classList.add("gs-modal"),e!="default"&&n.classList.add(e);const r=a=>{var o;switch(a.key){case"Escape":{const s=n.querySelector(".btn-cancel");s&&(s.click(),a.stopPropagation());break}case"Enter":{if(((o=a.target)==null?void 0:o.tagName)=="TEXTAREA")return;n.querySelector(".btn-primary").click(),a.stopPropagation();break}}};n.addEventListener("keydown",r),Vt($`<div class="backdrop"></div>
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<div class="content"></div>`,n);const i=()=>{n.querySelector(".backdrop").addEventListener("transitionend",()=>n.remove()),n.classList.remove("visible"),document.body.classList.remove(Ba)};return n.addEventListener("keydown",a=>{a.stopPropagation()}),n.addEventListener(hS,i),t.appendChild(n),window.requestAnimationFrame(()=>n.classList.add("visible")),e!="tour"&&document.body.classList.add(Ba),{content:n.querySelector(".content"),close:i}}function dn(e,t={}){const n=ao(),r=t.title;return t.okLabel??(t.okLabel="OK"),new Promise((i,a)=>{const o=()=>{n.close(),i(!0)},s=$`
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${r?$`<div class="modal-title">${r}</div>`:ue}
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<div class="modal-body" style="max-width: 700px">
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@@ -2569,7 +2572,7 @@ svg:not(:root).svg-inline--fa, svg:not(:host).svg-inline--fa {
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<div class="histogram-extent">
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${n.domain().map(a=>$`<div>${a}</div>`)}
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</div>`}}xc=new WeakMap,li=new WeakMap,la=new WeakMap,vf=new WeakMap,ep=new WeakSet,ZT=function(n){if(performance.now()<F(this,vf)+200)return;const r=n.target,i=Dw(r,n);J(this,wf,iv).call(this,"add",0,i[0]/r.offsetWidth)},tp=new WeakSet,QT=function(n,r){const a=n.target.closest(".histogram-threshold"),o=a.offsetLeft,s=a.offsetParent.offsetWidth;n.preventDefault(),n.stopPropagation(),this.style.cursor="col-resize",
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</div>`}}xc=new WeakMap,li=new WeakMap,la=new WeakMap,vf=new WeakMap,ep=new WeakSet,ZT=function(n){if(performance.now()<F(this,vf)+200)return;const r=n.target,i=Dw(r,n);J(this,wf,iv).call(this,"add",0,i[0]/r.offsetWidth)},tp=new WeakSet,QT=function(n,r){const a=n.target.closest(".histogram-threshold"),o=a.offsetLeft,s=a.offsetParent.offsetWidth;n.preventDefault(),n.stopPropagation(),this.style.cursor="col-resize",_G(n,(c,l)=>{J(this,wf,iv).call(this,"adjust",r,(o+c)/s)},()=>{le(this,vf,performance.now()),this.style.cursor=""})},wf=new WeakSet,iv=function(n,r,i){i=Ai(i,0,1),this.dispatchEvent(new SG(n,r,+F(this,la).invert(i*100).toPrecision(3)))},np=new WeakSet,XT=function(){const n=F(this,li),r=F(this,la),i=90/n.map(u=>u.length).reduce((u,f)=>Math.max(u,f),0),a=[],o=this.thresholds.length==1&&this.operators[0]=="eq",s=[-1/0,...this.thresholds,1/0],c=[!1,...this.operators.map(u=>["lte","gt"].includes(u)),!0],l=["gt","gte"].includes(this.operators[0])?u=>s.length-u-2:u=>u;for(let u=0;u<n.length;u++){const f=n[u],h=r(f.x0);let d=0,p=0;if(o)for(let g=0;g<=1;g++)p=kG(f,this.thresholds[0],g>0),p&&a.push({x:h,y:d*i,height:p*i,group:g}),d+=p;else if(this.thresholds.length)for(let g=0;g<s.length-1;g++){const b=l(g);p=CG(f,s[b],s[b+1],!c[b],c[b+1]),p&&a.push({x:h,y:d*i,height:p*i,group:g}),d+=p}else p=f.length,p&&a.push({x:h,y:d,height:p*i,group:null})}return a},zn(dS,"properties",{values:{attribute:!1},thresholds:{attribute:!1},operators:{attribute:!1},colors:{attribute:!1},showThresholdNumbers:{}}),customElements.define("genome-spy-histogram",dS);class SG extends Event{constructor(t,n,r){super(t),this.index=n,this.value=r}}function _G(e,t,n){const r=e.clientX,i=e.clientY,a=function(s){t(s.clientX-r,s.clientY-i)},o=function(s){document.removeEventListener("mousemove",a),document.removeEventListener("mouseup",o),n==null||n(s.clientX-r,s.clientY-i)};document.addEventListener("mousemove",a),document.addEventListener("mouseup",o)}function CG(e,t,n,r=!0,i=!1){const a=r?c=>c>=t:c=>c>t,o=i?c=>c<=n:c=>c<n;let s=0;for(let c=0;c<e.length;c++){const l=e[c];a(l)&&o(l)&&s++}return s}function kG(e,t,n=!1){let r=0;for(let i=0;i<e.length;i++)r+=+(e[i]==t);return n?e.length-r:r}const pS=["#1f77b4","#ff7f0e","#2ca02c","#d62728","#9467bd","#8c564b"];function TG(e,t){var r;const n=(r=e.scale)==null?void 0:r.type;Vn(n)?RG(e,t):_t(n)||Ii(n)?DG(e,t):e.type==="identifier"?IG(e,t):dn("Not implemented (yet).")}function IG(e,t){gS(t.getSamples().map(n=>n.id),e,t)}function RG(e,t){const n=e.scale,r=i=>$`<span
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class="color"
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style=${eh({backgroundColor:n(i).toString()})}
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></span>`;gS(n.domain(),e,t,r)}function gS(e,t,n,r=i=>ue){const i=n.provenance.storeHelper.getDispatcher(),a=new Set(mS(t,n.leafSamples,n.sampleHierarchy)),o=e.filter(x=>a.has(x)).map((x,C)=>({index:C,value:x,stringValue:`${x}`,lowerCaseValue:`${x}`.toLowerCase()})),s=ao(),c=$`
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@@ -2607,7 +2610,7 @@ svg:not(:root).svg-inline--fa, svg:not(:host).svg-inline--fa {
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@input=${p}
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>
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${
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${AG(x,I=>I.value,I=>$`<li>
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${r(I.value)}
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<input
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@@ -2623,7 +2626,7 @@ svg:not(:root).svg-inline--fa, svg:not(:host).svg-inline--fa {
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<div>Nothing found</div>
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</div>`:x.length==1&&o.length>1?$`<div class="search-note">
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<div>
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${Ue(
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${Ue(M$).node[0]} Hit enter to select the
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exact match
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</div>
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@@ -2634,7 +2637,7 @@ svg:not(:root).svg-inline--fa, svg:not(:host).svg-inline--fa {
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</small>
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${w()}`,s.content);const _=s.content.querySelector(".gs-checkbox-list");_.style.minHeight=`${_.offsetHeight}px`}A(),b()}function
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${w()}`,s.content);const _=s.content.querySelector(".gs-checkbox-list");_.style.minHeight=`${_.offsetHeight}px`}A(),b()}function DG(e,t){var b;const n=t.provenance.storeHelper.getDispatcher();let r="lt",i;const a=ao(),o=$`
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<div class="modal-title">Filter by <em>${e.name}</em></div>
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`,s=y=>{n(t.actions.filterByQuantitative({attribute:e.attribute,operator:r,operand:i})),a.close()},c=()=>$` <div class="modal-buttons">
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<button class="btn btn-cancel" @click=${()=>a.close()}>
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@@ -2654,7 +2657,7 @@ svg:not(:root).svg-inline--fa, svg:not(:host).svg-inline--fa {
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>Retain samples where <em>${e.name}</em> is</label
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>
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${Object.entries(
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${Object.entries(BG).map(([y,w])=>$`<button
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class=${f1({btn:!0,chosen:y==r})}
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BS=e=>Array.isArray(e)?e:[e];function ZG(e){const t=Array.isArray(e[0])?e[0]:e;return YG(t,"createSelector expects all input-selectors to be functions, but received the following types: "),t}function QG(e,t){const n=[],{length:r}=e;for(let i=0;i<r;i++)n.push(e[i].apply(null,t));return n}var XG=class{constructor(e){this.value=e}deref(){return this.value}},KG=WeakRef??XG,JG=0,FS=1;function Od(){return{s:JG,v:void 0,o:null,p:null}}function tb(e,t={}){let n=Od();const{resultEqualityCheck:r}=t;let i,a=0;function o(){let s=n;const{length:c}=arguments;for(let f=0,h=c;f<h;f++){const d=arguments[f];if(typeof d=="function"||typeof d=="object"&&d!==null){let p=s.o;p===null&&(s.o=p=new WeakMap);const g=p.get(d);g===void 0?(s=Od(),p.set(d,s)):s=g}else{let p=s.p;p===null&&(s.p=p=new Map);const g=p.get(d);g===void 0?(s=Od(),p.set(d,s)):s=g}}const l=s;let u;if(s.s===FS?u=s.v:(u=e.apply(null,arguments),a++),l.s=FS,r){const f=(i==null?void 0:i.deref())??i;f!=null&&r(f,u)&&(u=f,a!==0&&a--),i=typeof u=="object"&&u!==null||typeof u=="function"?new KG(u):u}return l.v=u,u}return o.clearCache=()=>{n=Od(),o.resetResultsCount()},o.resultsCount=()=>a,o.resetResultsCount=()=>{a=0},o}function PS(e,...t){const n=typeof e=="function"?{memoize:e,memoizeOptions:t}:e;return(...i)=>{let a=0,o=0,s,c={},l=i.pop();typeof l=="object"&&(c=l,l=i.pop()),WG(l,`createSelector expects an output function after the inputs, but received: [${typeof l}]`);const u={...n,...c},{memoize:f,memoizeOptions:h=[],argsMemoize:d=tb,argsMemoizeOptions:p=[],devModeChecks:g={}}=u,b=BS(h),y=BS(p),w=ZG(i),A=f(function(){return a++,l.apply(null,arguments)},...b),x=d(function(){o++;const _=QG(w,arguments);return s=A.apply(null,_),s},...y);return Object.assign(x,{resultFunc:l,memoizedResultFunc:A,dependencies:w,dependencyRecomputations:()=>o,resetDependencyRecomputations:()=>{o=0},lastResult:()=>s,recomputations:()=>a,resetRecomputations:()=>{a=0},memoize:f,argsMemoize:d})}}var eV=PS(tb);function MS(e){return({dispatch:n,getState:r})=>i=>a=>typeof a=="function"?a(n,r,e):i(a)}var tV=MS(),nV=MS,rV=(...e)=>{const t=PS(...e);return(...n)=>{const r=t(...n),i=(a,...o)=>r(Vi(a)?IS(a):a,...o);return Object.assign(i,r),i}};rV(tb);var iV=typeof window<"u"&&window.__REDUX_DEVTOOLS_EXTENSION_COMPOSE__?window.__REDUX_DEVTOOLS_EXTENSION_COMPOSE__:function(){if(arguments.length!==0)return typeof arguments[0]=="object"?Id:Id.apply(null,arguments)};function nu(e,t){function n(...r){if(t){let i=t(...r);if(!i)throw new Error(Kn(0));return{type:e,payload:i.payload,..."meta"in i&&{meta:i.meta},..."error"in i&&{error:i.error}}}return{type:e,payload:r[0]}}return n.toString=()=>`${e}`,n.type=e,n.match=r=>LG(r)&&r.type===e,n}var OS=class Rf extends Array{constructor(...t){super(...t),Object.setPrototypeOf(this,Rf.prototype)}static get[Symbol.species](){return Rf}concat(...t){return super.concat.apply(this,t)}prepend(...t){return t.length===1&&Array.isArray(t[0])?new Rf(...t[0].concat(this)):new Rf(...t.concat(this))}};function LS(e){return Zr(e)?DS(e,()=>{}):e}function NS(e,t,n){if(e.has(t)){let i=e.get(t);return n.update&&(i=n.update(i,t,e),e.set(t,i)),i}if(!n.insert)throw new Error(Kn(10));const r=n.insert(t,e);return e.set(t,r),r}function aV(e){return typeof e=="boolean"}var oV=()=>function(t){const{thunk:n=!0,immutableCheck:r=!0,serializableCheck:i=!0,actionCreatorCheck:a=!0}=t??{};let o=new OS;return n&&(aV(n)?o.push(tV):o.push(nV(n.extraArgument))),o},sV="RTK_autoBatch",zS=e=>t=>{setTimeout(t,e)},cV=typeof window<"u"&&window.requestAnimationFrame?window.requestAnimationFrame:zS(10),lV=(e={type:"raf"})=>t=>(...n)=>{const r=t(...n);let i=!0,a=!1,o=!1;const s=new Set,c=e.type==="tick"?queueMicrotask:e.type==="raf"?cV:e.type==="callback"?e.queueNotification:zS(e.timeout),l=()=>{o=!1,a&&(a=!1,s.forEach(u=>u()))};return Object.assign({},r,{subscribe(u){const f=()=>i&&u(),h=r.subscribe(f);return s.add(u),()=>{h(),s.delete(u)}},dispatch(u){var f;try{return i=!((f=u==null?void 0:u.meta)!=null&&f[sV]),a=!i,a&&(o||(o=!0,c(l))),r.dispatch(u)}finally{i=!0}}})},uV=e=>function(n){const{autoBatch:r=!0}=n??{};let i=new OS(e);return r&&i.push(lV(typeof r=="object"?r:void 0)),i},fV=!0;function hV(e){const t=oV(),{reducer:n=void 0,middleware:r,devTools:i=!0,preloadedState:a=void 0,enhancers:o=void 0}=e||{};let s;if(typeof n=="function")s=n;else if(G1(n))s=V1(n);else throw new Error(Kn(1));let c;typeof r=="function"?c=r(t):c=t();let l=Id;i&&(l=iV({trace:!fV,...typeof i=="object"&&i}));const u=OG(...c),f=uV(u);let h=typeof o=="function"?o(f):f();const d=l(...h);return yS(s,a,d)}function US(e){const t={},n=[];let r;const i={addCase(a,o){const s=typeof a=="string"?a:a.type;if(!s)throw new Error(Kn(28));if(s in t)throw new Error(Kn(29));return t[s]=o,i},addMatcher(a,o){return n.push({matcher:a,reducer:o}),i},addDefaultCase(a){return r=a,i}};return e(i),[t,n,r]}function dV(e){return typeof e=="function"}function pV(e,t){let[n,r,i]=US(t),a;if(dV(e))a=()=>LS(e());else{const s=LS(e);a=()=>s}function o(s=a(),c){let l=[n[c.type],...r.filter(({matcher:u})=>u(c)).map(({reducer:u})=>u)];return l.filter(u=>!!u).length===0&&(l=[i]),l.reduce((u,f)=>{if(f)if(Vi(u)){const d=f(u,c);return d===void 0?u:d}else{if(Zr(u))return DS(u,h=>f(h,c));{const h=f(u,c);if(h===void 0){if(u===null)return u;throw new Error(Kn(9))}return h}}return u},s)}return o.getInitialState=a,o}var gV=Symbol.for("rtk-slice-createasyncthunk");function mV(e,t){return`${e}/${t}`}function bV({creators:e}={}){var n;const t=(n=e==null?void 0:e.asyncThunk)==null?void 0:n[gV];return function(i){const{name:a,reducerPath:o=a}=i;if(!a)throw new Error(Kn(11));typeof process<"u";const s=(typeof i.reducers=="function"?i.reducers(vV()):i.reducers)||{},c=Object.keys(s),l={sliceCaseReducersByName:{},sliceCaseReducersByType:{},actionCreators:{},sliceMatchers:[]},u={addCase(b,y){const w=typeof b=="string"?b:b.type;if(!w)throw new Error(Kn(12));if(w in l.sliceCaseReducersByType)throw new Error(Kn(13));return l.sliceCaseReducersByType[w]=y,u},addMatcher(b,y){return l.sliceMatchers.push({matcher:b,reducer:y}),u},exposeAction(b,y){return l.actionCreators[b]=y,u},exposeCaseReducer(b,y){return l.sliceCaseReducersByName[b]=y,u}};c.forEach(b=>{const y=s[b],w={reducerName:b,type:mV(a,b),createNotation:typeof i.reducers=="function"};xV(y)?EV(w,y,u,t):wV(w,y,u)});function f(){const[b={},y=[],w=void 0]=typeof i.extraReducers=="function"?US(i.extraReducers):[i.extraReducers],A={...b,...l.sliceCaseReducersByType};return pV(i.initialState,x=>{for(let C in A)x.addCase(C,A[C]);for(let C of l.sliceMatchers)x.addMatcher(C.matcher,C.reducer);for(let C of y)x.addMatcher(C.matcher,C.reducer);w&&x.addDefaultCase(w)})}const h=b=>b,d=new WeakMap;let p;const g={name:a,reducerPath:o,reducer(b,y){return p||(p=f()),p(b,y)},actions:l.actionCreators,caseReducers:l.sliceCaseReducersByName,getInitialState(){return p||(p=f()),p.getInitialState()},getSelectors(b=h){const y=NS(d,this,{insert:()=>new WeakMap});return NS(y,b,{insert:()=>{const w={};for(const[A,x]of Object.entries(i.selectors??{}))w[A]=yV(this,x,b,this!==g);return w}})},selectSlice(b){let y=b[this.reducerPath];return typeof y>"u"&&this!==g&&(y=this.getInitialState()),y},get selectors(){return this.getSelectors(this.selectSlice)},injectInto(b,{reducerPath:y,...w}={}){const A=y??this.reducerPath;return b.inject({reducerPath:A,reducer:this.reducer},w),{...this,reducerPath:A}}};return g}}function yV(e,t,n,r){function i(a,...o){let s=n.call(e,a);return typeof s>"u"&&r&&(s=e.getInitialState()),t(s,...o)}return i.unwrapped=t,i}var $S=bV();function vV(){function e(t,n){return{_reducerDefinitionType:"asyncThunk",payloadCreator:t,...n}}return e.withTypes=()=>e,{reducer(t){return Object.assign({[t.name](...n){return t(...n)}}[t.name],{_reducerDefinitionType:"reducer"})},preparedReducer(t,n){return{_reducerDefinitionType:"reducerWithPrepare",prepare:t,reducer:n}},asyncThunk:e}}function wV({type:e,reducerName:t,createNotation:n},r,i){let a,o;if("reducer"in r){if(n&&!AV(r))throw new Error(Kn(17));a=r.reducer,o=r.prepare}else a=r;i.addCase(e,a).exposeCaseReducer(t,a).exposeAction(t,o?nu(e,o):nu(e))}function xV(e){return e._reducerDefinitionType==="asyncThunk"}function AV(e){return e._reducerDefinitionType==="reducerWithPrepare"}function EV({type:e,reducerName:t},n,r,i){if(!i)throw new Error(Kn(18));const{payloadCreator:a,fulfilled:o,pending:s,rejected:c,settled:l,options:u}=n,f=i(e,a,u);r.exposeAction(t,f),o&&r.addCase(f.fulfilled,o),s&&r.addCase(f.pending,s),c&&r.addCase(f.rejected,c),l&&r.addMatcher(f.settled,l),r.exposeCaseReducer(t,{fulfilled:o||Ld,pending:s||Ld,rejected:c||Ld,settled:l||Ld})}function Ld(){}var nb="listenerMiddleware";nu(`${nb}/add`),nu(`${nb}/removeAll`),nu(`${nb}/remove`);function Kn(e){return`Minified Redux Toolkit error #${e}; visit https://redux-toolkit.js.org/Errors?code=${e} for the full message or use the non-minified dev environment for full errors. `}function SV(e,t){var n=e+"",r=t+"";return n<r?-1:n==r?0:1}var _V=[].forEach;function CV(e,t,n){if(typeof t!="function")throw new TypeError(t+" is not a function");var r,i=[],a=[],o=[];_V.call(e,function(c,l,u){if(r=t(c,l,u),r===void 0)return void o.push(c);if(n===void 0&&typeof r=="symbol")throw new TypeError("Can't convert symbol to string");i.push(l),a[l]=r}),n===void 0&&(n=SV),i.sort(function(c,l){return n(a[c],a[l])});var s=i.map(function(c){return e[c]}).concat(o);return s.length!=e.length&&(s.length=e.length),s}function kV(e,t){const n=i=>i.copy().range(mi(0,i.domain().length)).unknown(-1);let r;switch(t.type){case"quantitative":r=i=>ft(i)&&!isNaN(i)?-i:-1/0;break;case"ordinal":r=n(t.scale);break;case"nominal":r=i=>i||"";break}return i=>r(e(i))}function TV(e,t){const n=new Set,r=i=>{const a=n.has(i);return n.add(i),a};return e.filter(i=>!r(t(i)))}function IV(e,t,n){const r=new Set,i=a=>(r.size<n&&r.add(a),r.has(a));return e.filter(a=>i(t(a)))}function RV(e,t,n=!1){return CV(e,t,(r,i)=>(n&&([r,i]=[i,r]),r<i?-1:r>i?1:0))}const DV={lt:(e,t)=>e<t,lte:(e,t)=>e<=t,eq:(e,t)=>e==t,gte:(e,t)=>e>=t,gt:(e,t)=>e>t};function BV(e,t,n,r){const i=DV[n];return e.filter(a=>i(t(a),r))}function HS(e,t,n,r){const i=new Set(r),a=s=>i.has(s),o=n=="remove"?s=>!a(s):a;return e.filter(s=>o(t(s)))}function FV(e,t){const n=r=>r!=null;return e.filter(r=>n(t(r)))}/**
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* @license
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* Copyright 2021 Google LLC
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* SPDX-License-Identifier: BSD-3-Clause
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*/function*
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+
*/function*PV(e,t){const n=typeof t=="function";if(e!==void 0){let r=-1;for(const i of e)r>-1&&(yield n?t(r):t),r++,yield i}}const GS="setSamples",VS="sortBy",jS="retainFirstOfEach",qS="retainFirstNCategories",WS="filterByNominal",YS="filterByQuantitative",ZS="removeUndefined",QS="groupByNominal",XS="groupToQuartiles",KS="groupByThresholds",JS="removeGroup",e_="retainMatched",Cs="sampleView";function MV(){return{sampleData:void 0,groupMetadata:[],rootGroup:{name:"ROOT",title:"Root",samples:[]}}}function OV(e){const t=(n,r)=>{const i=e(n.attribute).accessor;return a=>i(a,r)};return $S({name:Cs,initialState:MV(),reducers:{[GS]:(n,r)=>{const i=r.payload.samples;if(n.sampleData)throw new Error("Samples have already been set!");if(i.some(o=>o.id===void 0||o.id===null))throw new Error('The sample metadata contains missing sample ids or the "sample" column is missing!');if(new Set(i.map(o=>o.id)).size!=i.length)throw new Error("The sample metadata contains duplicate sample ids!");const a=i.map((o,s)=>({...o,indexNumber:s}));n.sampleData={ids:a.map(o=>o.id),entities:Object.fromEntries(a.map(o=>[o.id,o]))},n.rootGroup={name:"ROOT",title:"Root",samples:n.sampleData.ids}},[VS]:(n,r)=>{co(n,i=>RV(i,kV(t(r.payload,n),e(r.payload.attribute)),!1))},[jS]:(n,r)=>{co(n,i=>TV(i,t(r.payload,n)))},[qS]:(n,r)=>{co(n,i=>IV(i,t(r.payload,n),r.payload.n))},[YS]:(n,r)=>{co(n,i=>BV(i,t(r.payload,n),r.payload.operator,r.payload.operand))},[WS]:(n,r)=>{co(n,i=>HS(i,t(r.payload,n),r.payload.remove?"remove":"retain",r.payload.values))},[ZS]:(n,r)=>{co(n,i=>FV(i,t(r.payload,n)))},[QS]:(n,r)=>{var a;const i=(a=e(r.payload.attribute).scale)==null?void 0:a.domain();rb(n,o=>i_(o,t(r.payload,n),i)),n.groupMetadata.push({attribute:r.payload.attribute})},[XS]:(n,r)=>{rb(n,i=>UV(i,t(r.payload,n))),n.groupMetadata.push({attribute:r.payload.attribute})},[KS]:(n,r)=>{rb(n,i=>zV(i,t(r.payload,n),r.payload.thresholds)),n.groupMetadata.push({attribute:r.payload.attribute})},[JS]:(n,r)=>{const i=n.rootGroup;Nd(i)&&o_(i,r.payload.path)},[e_]:(n,r)=>{const i=t(r.payload,n),a=[];for(const s of ib(n))if(s.samples.length>0){const c=new Set;for(const l of s.samples)c.add(i(l));a.push(c)}const o=[];for(const s of a[0]){let c=!0;for(let l=1;l<a.length&&c;l++)c=a[l].has(s);c&&o.push(s)}co(n,s=>HS(s,i,"retain",o))}}})}function co(e,t){for(const n of ib(e))n.samples=t(n.samples)}function rb(e,t){for(const n of ib(e))t(n)}function ib(e){return ob(e).map(t=>xn(t))}function ab(e){return e.provenance.present[Cs]}function ob(e){const t=[],n=[],r=i=>{if(t.push(i),Nd(i))for(const a of i.groups)r(a);else n.push([...t]);t.pop()};return r(e.rootGroup),n}function t_(e){return"samples"in e}function Nd(e){return"groups"in e}function*sb(e){if(yield[e],Nd(e))for(const t of e.groups)for(const n of sb(t))yield[e,...n]}const LV=pt(".4"),n_={lt:"<",lte:"≤",eq:"=",gte:"≥",gt:">"};function r_(e){return $`{${e.map((t,n)=>$`${n>0?", ":""}<strong>${t}</strong>`)}}`}function NV(e,t){if(!e.type.startsWith(Cs))return;const n=e.payload,r=n.attribute&&t(n.attribute),i=r==null?void 0:r.name,a=(r==null?void 0:r.title)||$` <em>${i}</em> `,o={attributeName:i};switch(e.type.substring(Cs.length+1)){case GS:return{...o,title:"The initial state",icon:z$};case VS:return{...o,title:"Sort by",provenanceTitle:$` Sort by ${a} `,icon:b$};case jS:return{...o,title:$`
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Retain the first sample of each
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<em>${i}</em>
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@@ -2706,7 +2709,7 @@ svg:not(:root).svg-inline--fa, svg:not(:host).svg-inline--fa {
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<span class="operator"
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>${n_[n.operator]}</span
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>
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<strong>${
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<strong>${LV(n.operand)}</strong>
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`;return{...o,title:c($` <em>${i}</em> `),provenanceTitle:c(a),icon:Ja}}case ZS:return{...o,title:"Remove samples having missing attribute",provenanceTitle:$`
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Remove samples having missing ${a}
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`,icon:ld};case QS:return{...o,title:"Group by",provenanceTitle:$` Group by ${a} `,icon:Ul};case XS:return{...o,title:"Group by quartiles",provenanceTitle:$`
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@@ -2717,13 +2720,13 @@ svg:not(:root).svg-inline--fa, svg:not(:host).svg-inline--fa {
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on ${a}
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`,icon:Ul};case JS:return{title:"Remove group",provenanceTitle:$`
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Remove group
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${
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${PV(n.path.map(c=>$`<strong>${c}</strong>`)," / ")}
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`,icon:ld};case e_:return{...o,title:$`
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Retain group-wise matched samples using
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<em>${i}</em>
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Retain group-wise matched samples using ${a}
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`,icon:Ja};default:return{...o,title:JSON.stringify(e),icon:o4}}}function i_(e,t,n,r){if(r&&!n)throw new Error("Custom labels need explicit group order!");const i=Rc(e.samples,t),a=n?n.map(c=>[c,i.get(c)]).filter(c=>c[1]):[...i],s=e;s.groups=a.map(([c,l],u)=>({name:""+c,title:r?r[u]:c,samples:l})),delete e.samples}function a_(e,t,n){const r=o=>`Group ${o+1}`,i=mi(n.length-1).reverse(),a=s_(t,n.slice(1,n.length-1));i_(e,o=>r(a(o)),i.map(r),i.map(o=>l_(n[o],n[o+1])))}function
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|
+
`,icon:Ja};default:return{...o,title:JSON.stringify(e),icon:o4}}}function i_(e,t,n,r){if(r&&!n)throw new Error("Custom labels need explicit group order!");const i=Rc(e.samples,t),a=n?n.map(c=>[c,i.get(c)]).filter(c=>c[1]):[...i],s=e;s.groups=a.map(([c,l],u)=>({name:""+c,title:r?r[u]:c,samples:l})),delete e.samples}function a_(e,t,n){const r=o=>`Group ${o+1}`,i=mi(n.length-1).reverse(),a=s_(t,n.slice(1,n.length-1));i_(e,o=>r(a(o)),i.map(r),i.map(o=>l_(n[o],n[o+1])))}function zV(e,t,n){a_(e,t,[{operator:"lt",operand:-1/0},...n,{operator:"lte",operand:1/0}])}function UV(e,t){const n=HV($V(e.samples,t,[0,.25,.5,.75,1]));n.length==1&&n.push(n[0]),a_(e,t,n.map((r,i,a)=>({operator:i==a.length-1?"lte":"lt",operand:r})))}function o_(e,t){if(t.length==0)return;const n=e.groups.findIndex(r=>r.name==t[0]);if(!(n<0)){if(t.length==1)e.groups.splice(n,1);else if(t.length>1){const r=e.groups[n];Nd(r)&&o_(r,[...t].splice(1))}}}function s_(e,t){return r=>{const i=e(r);if(!(!ft(i)||isNaN(i))){for(let a=0;a<t.length;a++)if(t[a].operator=="lt"){if(i<t[a].operand)return a}else if(i<=t[a].operand)return a;return t.length}}}function $V(e,t,n){const r=nR(e.map(t).filter(i=>ft(i)&&!isNaN(i)));return n.map(i=>Fp(r,i))}function HV(e){const t=[e[0]];for(let n=1;n<e.length;n++)e[n]!=e[n-1]&&t.push(e[n]);return t}const c_=pt(".3~r"),l_=(e,t)=>`${e.operator=="lt"?"[":"("}${c_(e.operand)}, ${c_(t.operand)}${t.operator=="lte"?"]":")"}`;function GV(e,t){const n=t.provenance.storeHelper.getDispatcher(),r=[],i=ao(),a=$`
|
|
2727
2730
|
<div class="modal-title">
|
|
2728
2731
|
Group by threshold on <em>${e.name}</em>
|
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2729
2732
|
</div>
|
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@@ -2734,12 +2737,12 @@ svg:not(:root).svg-inline--fa, svg:not(:host).svg-inline--fa {
|
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2734
2737
|
|
|
2735
2738
|
<button
|
|
2736
2739
|
class="btn btn-primary"
|
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2737
|
-
?disabled=${!
|
|
2740
|
+
?disabled=${!VV(r)}
|
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2738
2741
|
@click=${()=>o()}
|
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2739
2742
|
>
|
|
2740
2743
|
${Ue(Ul).node[0]} Group
|
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2741
2744
|
</button>
|
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2742
|
-
</div>`,c=(b,y)=>(y>0&&(b=Math.max(b,r[y-1].operand)),y<r.length-1&&(b=Math.min(b,r[y+1].operand)),b),l=(b,y)=>{const w=b.target.value;r[y].operator=w,g()},u=(b,y)=>{const w=b.target.value;/^\d+(\.\d+)?$/.test(w)&&(r[y].operand=c(+w,y),g())},f=b=>{const y=r.findIndex(w=>w.operand>b.value);r.splice(y<0?r.length:y,0,{operand:b.value,operator:"lt"}),g()},h=b=>{r[b.index].operand=c(b.value,b.index),g()},d=b=>{r.splice(b,1),g()},p=
|
|
2745
|
+
</div>`,c=(b,y)=>(y>0&&(b=Math.max(b,r[y-1].operand)),y<r.length-1&&(b=Math.min(b,r[y+1].operand)),b),l=(b,y)=>{const w=b.target.value;r[y].operator=w,g()},u=(b,y)=>{const w=b.target.value;/^\d+(\.\d+)?$/.test(w)&&(r[y].operand=c(+w,y),g())},f=b=>{const y=r.findIndex(w=>w.operand>b.value);r.splice(y<0?r.length:y,0,{operand:b.value,operator:"lt"}),g()},h=b=>{r[b.index].operand=c(b.value,b.index),g()},d=b=>{r.splice(b,1),g()},p=jV(e,t.leafSamples,t.sampleHierarchy);function g(){const b=()=>{const w=[{operand:-1/0,operator:"lt"},...r,{operand:1/0,operator:"lte"}],A=s_(_=>_,w),x=[];for(let _=1;_<w.length;_++)x.push(0);for(const _ of p)x[A(_)-1]++;const C=[];for(let _=1;_<w.length;_++)C.push({index:_-1,name:_,interval:l_(w[_-1],w[_]),n:x[_-1]});return $`<table class="threshold-groups">
|
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2743
2746
|
<thead>
|
|
2744
2747
|
<tr>
|
|
2745
2748
|
<th>Group</th>
|
|
@@ -2807,7 +2810,7 @@ svg:not(:root).svg-inline--fa, svg:not(:host).svg-inline--fa {
|
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2807
2810
|
</div>
|
|
2808
2811
|
`;Vt($`${a}
|
|
2809
2812
|
<div class="modal-body">${y}</div>
|
|
2810
|
-
${s()}`,i.content)}g()}function
|
|
2813
|
+
${s()}`,i.content)}g()}function VV(e){return e.length}function jV(e,t,n){const r=e.accessor;return t.map(i=>r(i,n))}function qV(e,t){const n=t.provenance.storeHelper.getDispatcher();let r=5;const i=ao(),a=$`
|
|
2811
2814
|
<div class="modal-title">
|
|
2812
2815
|
Retain first n categories of <em>${e.title}</em>
|
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2813
2816
|
</div>
|
|
@@ -2831,19 +2834,19 @@ svg:not(:root).svg-inline--fa, svg:not(:host).svg-inline--fa {
|
|
|
2831
2834
|
</div>
|
|
2832
2835
|
`;function l(){Vt($`${a}
|
|
2833
2836
|
<div class="modal-body">${c}</div>
|
|
2834
|
-
${s()}`,i.content)}l(),i.content.querySelector("input").focus()}function cb(e,t,n,r){const i=r.actions,a=t.attribute,o=r.sampleHierarchy,s=r.provenance.storeHelper.getDispatcher(),c=[];e&&c.push({label:e,type:"header"});const l=(h,d,p)=>{const g=r.provenance.getActionInfo(h);return{label:g.title,icon:g.icon,callback:d?void 0:p??(()=>s(h))}},u=(...h)=>c.push(...h.map(d=>l(d)));u(i.sortBy({attribute:a}));const f=(t==null?void 0:t.type)??"identifier";return f!="quantitative"?(f!="identifier"&&(u(i.groupByNominal({attribute:a}),i.retainFirstOfEach({attribute:a})),c.push(l(i.retainFirstNCategories({attribute:a,n:void 0}),!1,()=>
|
|
2835
|
-
`]))}function XV(e){zd=e}function fb(e,t){const n=uo([],e,[]);return t&&(n._latestUnfiltered=null),n}function KV(e,t,n,r){const i=e.past.length+1;$t("inserting",t),$t("new free: ",n-i);const{past:a,_latestUnfiltered:o}=e,s=n&&n<=i,c=a.slice(s?1:0),l=o!=null?[...c,o]:c;return uo(l,t,[],r)}function f_(e,t){if(t<0||t>=e.future.length)return e;const{past:n,future:r,_latestUnfiltered:i}=e,a=[...n,i,...r.slice(0,t)],o=r[t],s=r.slice(t+1);return uo(a,o,s)}function h_(e,t){if(t<0||t>=e.past.length)return e;const{past:n,future:r,_latestUnfiltered:i}=e,a=n.slice(0,t),o=[...n.slice(t+1),i,...r],s=n[t];return uo(a,s,o)}function hb(e,t){return t>0?f_(e,t-1):t<0?h_(e,e.past.length+t):e}function JV(e,t){return t.indexOf(e)>-1?e:!e}function ej(e,t={}){XV(t.debug);const n={limit:void 0,filter:()=>!0,groupBy:()=>null,undoType:En.UNDO,redoType:En.REDO,jumpToPastType:En.JUMP_TO_PAST,jumpToFutureType:En.JUMP_TO_FUTURE,jumpType:En.JUMP,neverSkipReducer:!1,ignoreInitialState:!1,syncFilter:!1,...t,initTypes:u_(t.initTypes,["@@redux-undo/INIT"]),clearHistoryType:u_(t.clearHistoryType,[En.CLEAR_HISTORY])},r=n.neverSkipReducer?(a,o,...s)=>({...a,present:e(a.present,o,...s)}):a=>a;let i;return(a=i,o={},...s)=>{QV(o,a);let c=a;if(!i)if($t("history is uninitialized"),a===void 0){const u=e(a,{type:"@@redux-undo/CREATE_HISTORY"},...s);return c=fb(u,n.ignoreInitialState),$t("do not set initialState on probe actions"),Jn(c),c}else WV(a)?(c=i=n.ignoreInitialState?a:uo(a.past,a.present,a.future),$t("initialHistory initialized: initialState is a history",i)):(c=i=fb(a,n.ignoreInitialState),$t("initialHistory initialized: initialState is not a history",i));let l;switch(o.type){case void 0:return c;case n.undoType:return l=hb(c,-1),$t("perform undo"),Jn(l),r(l,o,...s);case n.redoType:return l=hb(c,1),$t("perform redo"),Jn(l),r(l,o,...s);case n.jumpToPastType:return l=h_(c,o.index),$t(`perform jumpToPast to ${o.index}`),Jn(l),r(l,o,...s);case n.jumpToFutureType:return l=f_(c,o.index),$t(`perform jumpToFuture to ${o.index}`),Jn(l),r(l,o,...s);case n.jumpType:return l=hb(c,o.index),$t(`perform jump to ${o.index}`),Jn(l),r(l,o,...s);case JV(o.type,n.clearHistoryType):return l=fb(c.present,n.ignoreInitialState),$t("perform clearHistory"),Jn(l),r(l,o,...s);default:if(l=e(c.present,o,...s),n.initTypes.some(f=>f===o.type))return $t("reset history due to init action"),Jn(i),i;if(c._latestUnfiltered===l)return c;if(typeof n.filter=="function"&&!n.filter(o,l,c)){const f=uo(c.past,l,c.future,c.group);return n.syncFilter||(f._latestUnfiltered=c._latestUnfiltered),$t("filter ignored action, not storing it in past"),Jn(f),f}const u=n.groupBy(o,l,c);if(u!=null&&u===c.group){const f=uo(c.past,l,c.future,c.group);return $t("groupBy grouped the action with the previous action"),Jn(f),f}return c=KV(c,l,n.limit,u),$t("inserted new state into history"),Jn(c),c}}}function Ud(e){return e.split("-")[0]}function db(e){return e.split("-")[1]}function pb(e){return["top","bottom"].includes(Ud(e))?"x":"y"}function d_(e){return e==="y"?"height":"width"}function p_(e,t,n){let{reference:r,floating:i}=e;const a=r.x+r.width/2-i.width/2,o=r.y+r.height/2-i.height/2,s=pb(t),c=d_(s),l=r[c]/2-i[c]/2,u=s==="x";let f;switch(Ud(t)){case"top":f={x:a,y:r.y-i.height};break;case"bottom":f={x:a,y:r.y+r.height};break;case"right":f={x:r.x+r.width,y:o};break;case"left":f={x:r.x-i.width,y:o};break;default:f={x:r.x,y:r.y}}switch(db(t)){case"start":f[s]-=l*(n&&u?-1:1);break;case"end":f[s]+=l*(n&&u?-1:1)}return f}const tj=async(e,t,n)=>{const{placement:r="bottom",strategy:i="absolute",middleware:a=[],platform:o}=n,s=await(o.isRTL==null?void 0:o.isRTL(t));let c=await o.getElementRects({reference:e,floating:t,strategy:i}),{x:l,y:u}=p_(c,r,s),f=r,h={};for(let d=0;d<a.length;d++){const{name:p,fn:g}=a[d],{x:b,y,data:w,reset:A}=await g({x:l,y:u,initialPlacement:r,placement:f,strategy:i,middlewareData:h,rects:c,platform:o,elements:{reference:e,floating:t}});l=b??l,u=y??u,h={...h,[p]:{...h[p],...w}},A&&(typeof A=="object"&&(A.placement&&(f=A.placement),A.rects&&(c=A.rects===!0?await o.getElementRects({reference:e,floating:t,strategy:i}):A.rects),{x:l,y:u}=p_(c,f,s)),d=-1)}return{x:l,y:u,placement:f,strategy:i,middlewareData:h}};function nj(e){return typeof e!="number"?function(t){return{top:0,right:0,bottom:0,left:0,...t}}(e):{top:e,right:e,bottom:e,left:e}}function $d(e){return{...e,top:e.y,left:e.x,right:e.x+e.width,bottom:e.y+e.height}}async function rj(e,t){var n;t===void 0&&(t={});const{x:r,y:i,platform:a,rects:o,elements:s,strategy:c}=e,{boundary:l="clippingAncestors",rootBoundary:u="viewport",elementContext:f="floating",altBoundary:h=!1,padding:d=0}=t,p=nj(d),g=s[h?f==="floating"?"reference":"floating":f],b=$d(await 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oj={start:"end",end:"start"};function g_(e){return e.replace(/start|end/g,t=>oj[t])}["top","right","bottom","left"].reduce((e,t)=>e.concat(t,t+"-start",t+"-end"),[]);const m_=function(e){return e===void 0&&(e={}),{name:"flip",options:e,async fn(t){var n;const{placement:r,middlewareData:i,rects:a,initialPlacement:o,platform:s,elements:c}=t,{mainAxis:l=!0,crossAxis:u=!0,fallbackPlacements:f,fallbackStrategy:h="bestFit",flipAlignment:d=!0,...p}=e,g=Ud(r),b=f||(g===o||!d?[Hd(o)]:function(D){const M=Hd(D);return[g_(D),M,g_(M)]}(o)),y=[o,...b],w=await rj(t,p),A=[];let x=((n=i.flip)==null?void 0:n.overflows)||[];if(l&&A.push(w[g]),u){const{main:D,cross:M}=aj(r,a,await(s.isRTL==null?void 0:s.isRTL(c.floating)));A.push(w[D],w[M])}if(x=[...x,{placement:r,overflows:A}],!A.every(D=>D<=0)){var C,_;const D=((C=(_=i.flip)==null?void 0:_.index)!=null?C:0)+1,M=y[D];if(M)return{data:{index:D,overflows:x},reset:{placement:M}};let G="bottom";switch(h){case"bestFit":{var I;const 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|
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+
${s()}`,i.content)}l(),i.content.querySelector("input").focus()}function cb(e,t,n,r){const i=r.actions,a=t.attribute,o=r.sampleHierarchy,s=r.provenance.storeHelper.getDispatcher(),c=[];e&&c.push({label:e,type:"header"});const l=(h,d,p)=>{const g=r.provenance.getActionInfo(h);return{label:g.title,icon:g.icon,callback:d?void 0:p??(()=>s(h))}},u=(...h)=>c.push(...h.map(d=>l(d)));u(i.sortBy({attribute:a}));const f=(t==null?void 0:t.type)??"identifier";return f!="quantitative"?(f!="identifier"&&(u(i.groupByNominal({attribute:a}),i.retainFirstOfEach({attribute:a})),c.push(l(i.retainFirstNCategories({attribute:a,n:void 0}),!1,()=>qV(t,r)))),u(i.filterByNominal({attribute:a,values:[n]}),i.filterByNominal({attribute:a,remove:!0,values:[n]})),f!="identifier"&&c.push(l(i.retainMatched({attribute:a}),!o.groupMetadata.length))):(u(i.groupToQuartiles({attribute:a})),c.push({icon:Ul,label:"Group by thresholds...",callback:()=>GV(t,r)}),WV(n)?u(i.filterByQuantitative({attribute:a,operator:"gte",operand:+n}),i.filterByQuantitative({attribute:a,operator:"lte",operand:+n})):u(i.removeUndefined({attribute:a}))),c.push({icon:Ja,label:"Advanced filter...",callback:()=>TG(t,r)}),c}function WV(e){return e!=null&&e!==""&&!(typeof e=="number"&&isNaN(e))}const En={UNDO:"@@redux-undo/UNDO",REDO:"@@redux-undo/REDO",JUMP_TO_FUTURE:"@@redux-undo/JUMP_TO_FUTURE",JUMP_TO_PAST:"@@redux-undo/JUMP_TO_PAST",JUMP:"@@redux-undo/JUMP",CLEAR_HISTORY:"@@redux-undo/CLEAR_HISTORY"},lo={undo(){return{type:En.UNDO}},redo(){return{type:En.REDO}},jumpToFuture(e){return{type:En.JUMP_TO_FUTURE,index:e}},jumpToPast(e){return{type:En.JUMP_TO_PAST,index:e}},jump(e){return{type:En.JUMP,index:e}},clearHistory(){return{type:En.CLEAR_HISTORY}}};function u_(e,t=[]){return Array.isArray(e)?e:typeof e=="string"?[e]:t}function YV(e){return typeof e.present<"u"&&typeof e.future<"u"&&typeof e.past<"u"&&Array.isArray(e.future)&&Array.isArray(e.past)}function uo(e,t,n,r=null){return{past:e,present:t,future:n,group:r,_latestUnfiltered:t,index:e.length,limit:e.length+n.length+1}}let zd,Sn;const lb={prevState:"#9E9E9E",action:"#03A9F4",nextState:"#4CAF50"};function ZV(){Sn={header:[],prev:[],action:[],next:[],msgs:[]}}function QV(){const{header:e,prev:t,next:n,action:r,msgs:i}=Sn;console.group?(console.groupCollapsed(...e),console.log(...t),console.log(...r),console.log(...n),console.log(...i),console.groupEnd()):(console.log(...e),console.log(...t),console.log(...r),console.log(...n),console.log(...i))}function ub(e,t,n){return[`%c${e}`,`color: ${t}; font-weight: bold`,n]}function XV(e,t){ZV(),zd&&(console.group?(Sn.header=["%credux-undo","font-style: italic","action",e.type],Sn.action=ub("action",lb.action,e),Sn.prev=ub("prev history",lb.prevState,t)):(Sn.header=["redux-undo action",e.type],Sn.action=["action",e],Sn.prev=["prev history",t]))}function Jn(e){zd&&(console.group?Sn.next=ub("next history",lb.nextState,e):Sn.next=["next history",e],QV())}function $t(...e){zd&&(Sn.msgs=Sn.msgs.concat([...e,`
|
|
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|
+
`]))}function KV(e){zd=e}function fb(e,t){const n=uo([],e,[]);return t&&(n._latestUnfiltered=null),n}function JV(e,t,n,r){const i=e.past.length+1;$t("inserting",t),$t("new free: ",n-i);const{past:a,_latestUnfiltered:o}=e,s=n&&n<=i,c=a.slice(s?1:0),l=o!=null?[...c,o]:c;return uo(l,t,[],r)}function f_(e,t){if(t<0||t>=e.future.length)return e;const{past:n,future:r,_latestUnfiltered:i}=e,a=[...n,i,...r.slice(0,t)],o=r[t],s=r.slice(t+1);return uo(a,o,s)}function h_(e,t){if(t<0||t>=e.past.length)return e;const{past:n,future:r,_latestUnfiltered:i}=e,a=n.slice(0,t),o=[...n.slice(t+1),i,...r],s=n[t];return uo(a,s,o)}function hb(e,t){return t>0?f_(e,t-1):t<0?h_(e,e.past.length+t):e}function ej(e,t){return t.indexOf(e)>-1?e:!e}function tj(e,t={}){KV(t.debug);const n={limit:void 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x_=Math.min,iu=Math.max,Vd=Math.round;function fo(e,t,n){var r,i,a,o;t===void 0&&(t=!1),n===void 0&&(n=!1);const s=e.getBoundingClientRect();let c=1,l=1;t&&vr(e)&&(c=e.offsetWidth>0&&Vd(s.width)/e.offsetWidth||1,l=e.offsetHeight>0&&Vd(s.height)/e.offsetHeight||1);const u=ks(e)?Qr(e):window,f=!w_()&&n,h=(s.left+(f&&(r=(i=u.visualViewport)==null?void 0:i.offsetLeft)!=null?r:0))/c,d=(s.top+(f&&(a=(o=u.visualViewport)==null?void 0:o.offsetTop)!=null?a:0))/l,p=s.width/c,g=s.height/l;return{width:p,height:g,top:d,right:h+p,bottom:d+g,left:h,x:h,y:d}}function ji(e){return(t=e,(t instanceof Qr(t).Node?e.ownerDocument:e.document)||window.document).documentElement;var t}function jd(e){return ks(e)?{scrollLeft:e.scrollLeft,scrollTop:e.scrollTop}:{scrollLeft:e.pageXOffset,scrollTop:e.pageYOffset}}function A_(e){return fo(ji(e)).left+jd(e).scrollLeft}function uj(e,t,n){const r=vr(t),i=ji(t),a=fo(e,r&&function(c){const l=fo(c);return 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t=fo(e);return{width:t.width,height:t.height}}function C_(e){const t=E_(e);return["html","body","#document"].includes(Xr(t))?e.ownerDocument.body:vr(t)&&Gd(t)?t:C_(t)}function k_(e,t){var n;t===void 0&&(t=[]);const r=C_(e),i=r===((n=e.ownerDocument)==null?void 0:n.body),a=Qr(r),o=i?[a].concat(a.visualViewport||[],Gd(r)?r:[]):r,s=t.concat(o);return i?s:s.concat(k_(o))}function T_(e,t,n){return t==="viewport"?$d(function(r,i){const a=Qr(r),o=ji(r),s=a.visualViewport;let c=o.clientWidth,l=o.clientHeight,u=0,f=0;if(s){c=s.width,l=s.height;const h=w_();(h||!h&&i==="fixed")&&(u=s.offsetLeft,f=s.offsetTop)}return{width:c,height:l,x:u,y:f}}(e,n)):ks(t)?function(r,i){const a=fo(r,!1,i==="fixed"),o=a.top+r.clientTop,s=a.left+r.clientLeft;return{top:o,left:s,x:s,y:o,right:s+r.clientWidth,bottom:o+r.clientHeight,width:r.clientWidth,height:r.clientHeight}}(t,n):$d(function(r){var i;const a=ji(r),o=jd(r),s=(i=r.ownerDocument)==null?void 0:i.body,c=iu(a.scrollWidth,a.clientWidth,s?s.scrollWidth:0,s?s.clientWidth:0),l=iu(a.scrollHeight,a.clientHeight,s?s.scrollHeight:0,s?s.clientHeight:0);let u=-o.scrollLeft+A_(r);const f=-o.scrollTop;return ru(s||a).direction==="rtl"&&(u+=iu(a.clientWidth,s?s.clientWidth:0)-c),{width:c,height:l,x:u,y:f}}(ji(e)))}function fj(e){const t=k_(e),n=["absolute","fixed"].includes(ru(e).position)&&vr(e)?mb(e):e;return ks(n)?t.filter(r=>ks(r)&&function(i,a){const o=a==null||a.getRootNode==null?void 0:a.getRootNode();if(i!=null&&i.contains(a))return!0;if(o&&gb(o)){let s=a;do{if(s&&i===s)return!0;s=s.parentNode||s.host}while(s)}return!1}(r,n)&&Xr(r)!=="body"):[]}const hj={getClippingRect:function(e){let{element:t,boundary:n,rootBoundary:r,strategy:i}=e;const a=[...n==="clippingAncestors"?fj(t):[].concat(n),r],o=a[0],s=a.reduce((c,l)=>{const u=T_(t,l,i);return c.top=iu(u.top,c.top),c.right=x_(u.right,c.right),c.bottom=x_(u.bottom,c.bottom),c.left=iu(u.left,c.left),c},T_(t,o,i));return{width:s.right-s.left,height:s.bottom-s.top,x:s.left,y:s.top}},convertOffsetParentRelativeRectToViewportRelativeRect:function(e){let{rect:t,offsetParent:n,strategy:r}=e;const i=vr(n),a=ji(n);if(n===a)return t;let o={scrollLeft:0,scrollTop:0};const s={x:0,y:0};if((i||!i&&r!=="fixed")&&((Xr(n)!=="body"||Gd(a))&&(o=jd(n)),vr(n))){const c=fo(n,!0);s.x=c.x+n.clientLeft,s.y=c.y+n.clientTop}return{...t,x:t.x-o.scrollLeft+s.x,y:t.y-o.scrollTop+s.y}},isElement:ks,getDimensions:__,getOffsetParent:mb,getDocumentElement:ji,getElementRects:e=>{let{reference:t,floating:n,strategy:r}=e;return{reference:uj(t,mb(n),r),floating:{...__(n),x:0,y:0}}},getClientRects:e=>Array.from(e.getClientRects()),isRTL:e=>ru(e).direction==="rtl"},dj=(e,t,n)=>nj(e,t,{platform:hj,...n});let wr;const au=[],bb=bs(e=>e(),150,!1),yb={type:"divider"};function ou(e){if((e==null?void 0:e.type)=="contextmenu"){e.preventDefault();return}wr&&(wr.remove(),wr=void 0,document.body.classList.remove(Ba))}function I_(e){var t;if(!(e<1)){for(let n=e;n<au.length;n++)(t=au[n])==null||t.remove(),au[n]=void 0;for(const n of au[e-1].querySelectorAll("li.active"))n.classList.remove("active")}}const pj=()=>$`<li class="menu-divider"></li>`,gj=e=>$` <li class="menu-header">${e.label||"-"}</li> `,mj=(e,t)=>$`
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@mouseenter=${n=>bb(()=>{const r=n.target.closest("li");
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@mouseenter=${n=>bb(()=>{const r=n.target.closest("li");vj(e.submenu,r,t+1),n.stopPropagation()})}
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@mouseleave=${()=>bb(()=>I_(t+1))}
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><span>${e.label}</span></a
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>
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@@ -2860,17 +2863,17 @@ svg:not(:root).svg-inline--fa, svg:not(:host).svg-inline--fa {
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class="menu-ellipsis"
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@click=${e.ellipsisCallback}
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>
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${Ue(
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>
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`;function R_(e,t=1){switch(e.type){case"divider":return
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`;function R_(e,t=1){switch(e.type){case"divider":return pj();case"header":return gj(e);default:return e.submenu?mj(e,t):e.callback?bj(e):yj(e)}}function vj(e,t,n){D_(e,t,n,"right-start"),t.classList.add("active")}function D_(e,t,n,r){const i=document.createElement("ul");i.classList.add("gs-context-menu"),i.addEventListener("mouseenter",()=>{bb(()=>{})}),Vt(e.map(a=>R_(a,n)),i),wr.appendChild(i),I_(n),au[n]=i,dj(t,i,{placement:r??"right-start",middleware:n?[m_()]:[cj(2),m_()]}).then(({x:a,y:o})=>{const s=i.querySelector(":scope > li");s&&(o-=s.getBoundingClientRect().top),i.style.left=`${a}px`,i.style.top=`${o}px`})}function B_(e,t,n){n??(n="bottom-start"),ou();const r=performance.now(),i=document.body;wr=document.createElement("div"),wr.classList.add("gs-context-menu-backdrop"),wr.addEventListener("click",ou),wr.addEventListener("contextmenu",ou),wr.addEventListener("mouseup",()=>{performance.now()-r>500&&ou()},{once:!0}),i.appendChild(wr),document.body.classList.add(Ba),D_(e.items,t,0,n)}function vb(e,t){B_(e,wj(t),"right-start"),t.preventDefault()}function wj(e){return{getBoundingClientRect(){return{width:0,height:0,x:e.clientX,y:e.clientY,top:e.clientY,left:e.clientX,right:e.clientX,bottom:e.clientY,toJSON:void 0}}}}const wb={NOMINAL:"nominal",ORDINAL:"ordinal",QUANTITATIVE:"quantitative"},qd="SAMPLE_ATTRIBUTE",F_="SAMPLE_NAME",xj=/^attribute-(.*)$/;class P_ extends ys{constructor(n,r){super({title:"Sample metadata",data:{name:null},hconcat:[],spacing:n.spec.samples.attributeSpacing??1,padding:{right:10},resolve:{scale:{default:"independent"},axis:{default:"independent"}}},n.context,n,r,"sample-metadata");Z(this,rp);Z(this,ip);Z(this,ap);Z(this,op);Z(this,Uo);Z(this,sp);Z(this,et,void 0);le(this,et,n),this._attributeHighlighState={backgroundOpacity:1,currentAttribute:void 0,abortController:new AbortController},F(this,et).compositeAttributeInfoSource.addAttributeInfoSource(qd,i=>this.children.map(J(this,Uo,Df).bind(this)).find(a=>a&&a.name==i.specifier)),F(this,et).compositeAttributeInfoSource.addAttributeInfoSource(F_,i=>M_),this.addInteractionEventListener("contextmenu",this.handleContextMenu.bind(this)),this.addInteractionEventListener("mousemove",(i,a)=>{var l;const o=a.target,s=F(this,et).findSampleForMouseEvent(i,a),c=o&&((l=J(this,Uo,Df).call(this,o))==null?void 0:l.name)||void 0;if(s){const u=JSON.stringify([s.id,c]);this.context.updateTooltip(u,f=>Promise.resolve(J(this,sp,nI).call(this,f)))}this._handleAttributeHighlight(c)}),xn([...F(this,et).getLayoutAncestors()]).addInteractionEventListener("mousemove",(i,a)=>{if(this._attributeHighlighState.currentAttribute){if(a.target){for(const o of a.target.getLayoutAncestors())if(o==this)return}this._handleAttributeHighlight(void 0)}})}getEncoding(){return{}}render(n,r,i={}){this.isConfiguredVisible()&&super.render(n,r,{...i,clipRect:F(this,et).locationManager.clipBySummary(r)})}_handleAttributeHighlight(n){const r=this._attributeHighlighState;n!=r.currentAttribute&&(r.abortController.abort(),r.abortController=new AbortController,this.context.animator.transition({from:r.backgroundOpacity,onUpdate:i=>{r.backgroundOpacity=i},easingFunction:LN,signal:r.abortController.signal,...n?{to:.1,duration:1e3,delay:r.backgroundOpacity<1?0:500}:{to:1,duration:200,delay:150}}).catch(i=>{}),this.context.animator.requestRender()),r.currentAttribute=n}getSample(n){var r;return(r=F(this,et).sampleHierarchy.sampleData)==null?void 0:r.entities[n]}handleContextMenu(n,r){const i=r.uiEvent,a=F(this,et).findSampleForMouseEvent(n,r);if(!a){i.preventDefault();return}const o=[F(this,et).makePeekMenuItem(),yb],s=J(this,Uo,Df).call(this,r.target);if(s){const c=a.attributes[s.name];o.push(...cb($`Attribute: <strong>${s.name}</strong>`,s,c,F(this,et)))}else o.push(...cb($`Sample: <strong>${a.displayName}</strong>`,M_,a.id,F(this,et)));vb({items:o},i)}setSamples(n){if(this.childCount)throw new Error("Children are already created!");this._createViews();const r=this.context.dataFlow;BE(this,r);const i=r.findDataSourceByKey(this);i.visit(o=>o.initialize());const a=[];this.visit(o=>{if(o instanceof mt){const s=o.mark;s.initializeEncoders(),a.push(s.initializeGraphics().then(c=>s)),r.addObserver(c=>{s.initializeData(),s.updateGraphicsData()},o)}}),Promise.allSettled(a).then(o=>{for(const s of o)"value"in s?s.value.finalizeGraphicsInitialization():"reason"in s&&console.error(s.reason)}),i.updateDynamicData(n),this.visit(o=>{o.name.startsWith("title")&&r.findDataSourceByKey(o).load()})}_createViews(){const n=[];n.push(this.context.createView(Ej(F(this,et).spec.samples),this,this));for(const r of this.getAttributeNames()){const i=this.context.createView(J(this,ap,eI).call(this,r),this,this);i.opacityFunction=a=>a*J(this,rp,KT).call(this,r),n.push(i)}this.setChildren(n);for(const r of this.getDescendants())r instanceof mt&&r.name.startsWith("title")&&typeof r.spec.mark!="string"&&(r.spec.mark.clip="never");PE(this)}getAttributeNames(){return this._cache("attributeNames",()=>[...F(this,et).getSamples().flatMap(i=>Object.keys(i.attributes)).reduce((i,a)=>i.add(a),new Set)])}getAttributeInfo(n){return J(this,Uo,Df).call(this,J(this,op,tI).call(this,n))}getDefaultResolution(n,r){return"independent"}handleVerboseCommand(n){const r=n;for(const i of this.getAttributeNames()){const a=this.getAttributeInfo(i);if((a.type==qm||a.type==Wm)&&F(this,et).getSamples().find(s=>s.attributes[a.name]==r)){const s=F(this,et).actions.filterByNominal({attribute:{type:qd,specifier:i},values:[r]}),c=F(this,et).provenance.getPresentState().lastAction,l=F(this,et).actions.filterByNominal.match(c)&&!c.payload.remove&&c.payload.attribute.type==qd&&c.payload.attribute.specifier==i&&c.payload.values.length==1;return F(this,et).provenance.storeHelper.dispatch(l?[lo.undo(),s]:s),!0}}return!1}isPickingSupported(){return!1}}et=new WeakMap,rp=new WeakSet,KT=function(n){const r=this._attributeHighlighState;return n==r.currentAttribute?1:r.backgroundOpacity},ip=new WeakSet,JT=function(n){var r,i;return(i=(r=F(this,et).spec.samples)==null?void 0:r.attributes)==null?void 0:i[n]},ap=new WeakSet,eI=function(n){const r=J(this,ip,JT).call(this,n);let i=r?r.type:void 0;if(!i){const a=F(this,et).getSamples();switch(lw(a.map(o=>o.attributes[n]))){case"integer":case"number":i=wb.QUANTITATIVE;break;default:i=wb.NOMINAL}}return Aj(n,{...r||{},type:i},F(this,et).spec.samples)},op=new WeakSet,tI=function(n){return this.children[this.getAttributeNames().indexOf(n)+1]},Uo=new WeakSet,Df=function(n){const r=n==null?void 0:n.name.match(xj);if(r){const i=n.getScaleResolution("color"),a=r[1];return{name:a,attribute:{type:qd,specifier:a},accessor:(o,s)=>s.sampleData.entities[o].attributes[a],type:i.type,scale:i.getScale(),title:$`<em class="attribute">${a}</em>`}}},sp=new WeakSet,nI=function(n){const[r,i]=JSON.parse(n),a=this.getSample(r),o=(c,l)=>Sj(l)?this.getAttributeInfo(c).scale(l):"transparent",s=$`
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${Object.entries(a.attributes).map(([c,l])=>$`
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<tr class=${f1({hovered:c==i})}>
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@@ -2888,24 +2891,24 @@ svg:not(:root).svg-inline--fa, svg:not(:host).svg-inline--fa {
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<strong>${a.displayName||a.id}</strong>
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${s}
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`};function xj(e,t,n){const r=`attributes["${e}"]`,i={name:`attribute-${e}`,title:{text:e,orient:"bottom",align:"right",baseline:"middle",offset:5,angle:-90+(n.attributeLabelAngle??0),dy:-.5,font:n.attributeLabelFont,fontSize:n.attributeLabelFontSize??11,fontStyle:n.attributeLabelFontStyle,fontWeight:n.attributeLabelFontWeight},visible:t.visible??!0,width:t.width??n.attributeSize??10,transform:[{type:"filter",expr:`datum.${r} != null`}],mark:{type:"rect",xOffset:-.5},encoding:{facetIndex:{field:"indexNumber"},color:{field:r,type:t.type,scale:t.scale}},opacity:1};return t.barScale&&t.type==wb.QUANTITATIVE&&(i.encoding.x={field:`attributes["${e}"]`,type:t.type,scale:t.barScale,axis:null}),i}function Aj(e){return{name:"metadata-sample-name",title:{text:e.labelTitleText??"Sample name",orient:"bottom",anchor:"start",offset:5,font:e.attributeLabelFont,fontSize:e.attributeLabelFontSize??11,fontStyle:e.attributeLabelFontStyle,fontWeight:e.attributeLabelFontWeight},width:e.labelLength??140,mark:{type:"text",baseline:"middle",font:e.labelFont,size:e.labelFontSize??11,fontStyle:e.labelFontStyle,fontWeight:e.labelFontWeight,align:e.labelAlign??"left",flushY:!1},encoding:{facetIndex:{field:"indexNumber"},x:{value:0},x2:{value:1},y:{value:0},y2:{value:1},text:{field:"displayName"}}}}function Ej(e){return e!==""&&!(typeof e=="number"&&isNaN(e))&&e!==null}const M_=Object.freeze({name:"sample",attribute:{type:F_},accessor:e=>e,type:"identifier",scale:void 0});class Sj extends Ka{constructor(n,r){super({title:{text:"Groups",orient:"none"},padding:{right:0},width:{step:22},data:{name:null},transform:[{type:"filter",expr:"datum._depth > 0"},{type:"formula",as:"_y1",expr:"datum._index * 2"},{type:"formula",as:"_y2",expr:"datum._index * 2 + 1"},{type:"formula",as:"_title",expr:"datum.title || datum.name"},{type:"formula",as:"_NA",expr:"datum._title === null"},{type:"formula",as:"_title",expr:"datum._title !== null ? datum._title: 'NA'"}],encoding:{x:{field:"_depth",type:"ordinal",scale:{align:0,padding:.2272727},axis:null},y:{field:"_y1",type:"nominal",scale:{type:"ordinal",domain:mi(500)},axis:null},y2:{field:"_y2"}},layer:[{title:"Group",mark:{type:"rect",clip:!0,color:"#e8e8e8",cornerRadiusBottomLeft:14,cornerRadiusTopLeft:14}},{mark:{type:"text",clip:!0,angle:-90,paddingY:5,tooltip:null},encoding:{text:{field:"_title"},opacity:{field:"_NA",type:"nominal",scale:{type:"ordinal",domain:[!1,!0],range:[1,.3]}}}}]},n.context,n,r,"sample-groups");Z(this,cp);this.sampleView=n,this._addBroadcastHandler("layoutComputed",()=>{this.updateRange()}),this.addInteractionEventListener("contextmenu",(i,a)=>{const o=a.uiEvent,s=this.context.getCurrentHover();if(!s)return;const c=s.datum._rawGroup;let l;for(const d of sb(this.sampleView.sampleHierarchy.rootGroup))if(d.at(-1)===c){l=d.slice(1);break}const u=n.actions.removeGroup({path:l.map(d=>d.name)}),f=n.provenance.getActionInfo(u),h=n.provenance.storeHelper.getDispatcher();vb({items:[{label:f.title,icon:f.icon,callback:()=>h(u)}]},o)})}updateRange(){var o,s;const n=(o=this.sampleView.locationManager.getLocations())==null?void 0:o.groups;if(!(n!=null&&n.length))return;const r=((s=this.sampleView)==null?void 0:s.childCoords.height)??0,i=this.getScaleResolution("y"),a=[];for(const c of n)a.push(1-(c.locSize.location+c.locSize.size)/r),a.push(1-c.locSize.location/r);i.getScale().range(a),this.context.glHelper.createRangeTexture(i,!0)}updateGroups(){var o;const n=((o=this.sampleView.locationManager.getLocations())==null?void 0:o.groups)??[],r=this.context.dataFlow.findDataSourceByKey(this);if(!r)return;const i=J(this,cp,rI).call(this),a=n.map(s=>({_index:s.key.index,_depth:s.key.depth,_rawGroup:s.key.group,attribute:i[s.key.depth],name:s.key.group.name,...s.key.group.name!=s.key.group.title?{title:s.key.group.title}:{},n:s.key.n}));r.updateDynamicData(a),this.getScaleResolution("x").reconfigure(),this.getScaleResolution("y").reconfigure(),n.length&&this.updateRange(),xn([...this.getLayoutAncestors()]).visit(s=>Il(s,"size"))}}cp=new WeakSet,rI=function(){const n=document.createElement("div");return[null,...this.sampleView.sampleHierarchy.groupMetadata].map(r=>{if(!r)return"unknown";const i=this.sampleView.compositeAttributeInfoSource.getAttributeInfo(r.attribute).title;return i?Me(i)?i:(Vt(i,n),n.textContent.replace(/\s+/g," ").trim()):"unknown"})};class _j{constructor(){this.attributeInfoSourcesByType={}}addAttributeInfoSource(t,n){this.attributeInfoSourcesByType[t]=n}getAttributeInfo(t){const n=this.attributeInfoSourcesByType[t.type];if(!n)throw new Error("Cannot find attribute info source for: "+JSON.stringify(t));const r=n(t);if(r)return r;throw new Error("Unknown attribute: "+JSON.stringify(t))}}function Wd(e,t,n){let r=n&&e(n);return i=>{const a=e(i);a!==r&&(t(a,r),r=a)}}class Cj{constructor(t){Z(this,Af);Z(this,Ln,0);Z(this,ua,0);Z(this,$o,0);Z(this,Ac,void 0);Z(this,Ec,void 0);Z(this,ui,void 0);Z(this,Sc,void 0);Z(this,It,void 0);Z(this,xf,void 0);le(this,It,t),le(this,xf,t.viewContext.paramBroker.allocateSetter("sampleHeight"))}isCloseup(){return F(this,Ln)===1}resetLocations(){le(this,ui,void 0)}reset(){le(this,Ln,0),this.resetLocations()}handleWheelEvent(t){le(this,ua,Ai(F(this,ua)+t.deltaY,0,F(this,$o)-F(this,It).getHeight()))}togglePeek(t,n,r){if(F(this,Ln)>0&&F(this,Ln)<1||t!==void 0&&t==!!F(this,Ln))return;const i=F(this,It).viewContext,a=F(this,It).getHeight(),o={requestAnimationFrame:s=>i.animator.requestTransition(s),onUpdate:s=>{le(this,Ln,Math.pow(s,2)),F(this,It).onLocationUpdate(),J(this,Af,av).call(this),i.animator.requestRender()},from:F(this,Ln)};if(F(this,Ln)==0){let s;if(r)s=(l=>l.location+l.size/2)(F(this,Sc).samples.find(l=>l.key==r).locSize);else{const c=this.getSummaryAt(n);c&&(s=F(this,Sc).summaries[c.index].locSize.location-(c.location.locSize.location-n))}s?le(this,ua,s-n):le(this,ua,(F(this,$o)-a)/2),F(this,$o)>a?rd({...o,to:1,duration:500,easingFunction:$N}):rd({...o,from:0,to:1,duration:300,easingFunction:l=>(1-Math.pow(l*2-1,2))*.5})}else rd({...o,to:0,duration:400,easingFunction:NN})}getLocations(){if(F(this,ui))return F(this,ui);const t=F(this,It).getHeight();if(!t)return;const n=F(this,It).getSampleHierarchy(),r=ob(n),i=F(this,It).getSummaryHeight(),a=O_(r,{viewHeight:t,groupSpacing:5,summaryHeight:i}),o=O_(r,{sampleHeight:35,groupSpacing:15,summaryHeight:i}),s=()=>-F(this,ua),c=()=>F(this,Ln);le(this,Sc,o),le(this,$o,o.summaries.map(f=>f.locSize.location+f.locSize.size).reduce((f,h)=>Math.max(f,h),0));const l=(f,h)=>{const d=[];for(let p=0;p<f.length;p++){const g=f[p].key;d.push({key:g,locSize:XL(f[p].locSize,KL(h[p].locSize,s),c)})}return d},u=l(a.groups,o.groups);return le(this,ui,{samples:l(a.samples,o.samples),summaries:l(a.summaries,o.summaries),groups:u}),J(this,Af,av).call(this),F(this,ui)}getGroupBackgroundRects(t){const n=this.getLocations().groups,r=n.map(s=>s.key.depth).reduce((s,c)=>Math.max(s,c),0),i=n.filter(s=>s.key.depth==r),a=F(this,It).getSummaryHeight();t=t.flatten();const o=F(this,It).isStickySummaries()&&a>0?t.shrink(new Ct(a,0,0,0)):t;return[...i.values()].map(s=>{const c=()=>{const l=s.locSize.location;return t.y+l+a};return{coords:t.modify({y:c,height:()=>s.locSize.size-a}).intersect(o),clipRect:o}})}updateFacetTexture(){const t=F(this,It).getSampleHierarchy().sampleData;if(!F(this,Ec)){const a=t&&Object.values(t.entities);le(this,Ec,new Float32Array(Math.ceil(a.length*2/4)*4))}const n=F(this,Ec);n.fill(0);const r=t==null?void 0:t.entities;if(r){const a=this.getLocations().samples,o=F(this,It).getHeight();for(const s of a){const c=r[s.key].indexNumber;n[c*2+0]=s.locSize.location/o,n[c*2+1]=s.locSize.size/o}}const i=F(this,It).viewContext.glHelper.gl;le(this,Ac,Dl(i,{internalFormat:i.RG32F,format:i.RG,height:1},n,F(this,Ac)))}getFacetTexture(){return F(this,Ac)}getSummaryAt(t){const n=this.getLocations().summaries,r=n.findIndex(i=>XA(i.locSize,t));return r>=0?{index:r,location:n[r]}:void 0}clipBySummary(t){if(F(this,It).isStickySummaries()){const n=F(this,It).getSummaryHeight();if(n>0)return t.modify({y:()=>t.y+n,height:()=>t.height-n})}return t}}Ln=new WeakMap,ua=new WeakMap,$o=new WeakMap,Ac=new WeakMap,Ec=new WeakMap,ui=new WeakMap,Sc=new WeakMap,It=new WeakMap,xf=new WeakMap,Af=new WeakSet,av=function(){var t;F(this,xf).call(this,((t=F(this,ui).samples[0])==null?void 0:t.locSize.size)??0)};function O_(e,{viewHeight:t=0,sampleHeight:n=0,groupSpacing:r=5,summaryHeight:i=0}){if(!t&&!n)throw new Error("viewHeight or sampleHeight must be provided!");const a=h=>xn(h),o=e.map(h=>({path:h,sampleGroup:a(h),samples:a(h).samples})).filter(h=>h.samples.length),s=n?h=>({px:h.length*n+i,grow:0}):h=>({px:i,grow:h.length}),c=[];Fl(o.map(h=>s(h.samples)),t,{spacing:r}).forEach((h,d)=>{c.push({key:o[d].path,locSize:h})});const l=[];for(const[h,d]of o.entries()){const p={grow:1},g=d.samples;Fl(g.map(b=>p),Math.max(0,c[h].locSize.size-i),{offset:c[h].locSize.location+i}).forEach((b,y)=>{const{size:w,location:A}=b,x=w*.1*pg(15,22,w);b.location=A+x,b.size=w-2*x,l.push({key:g[y],locSize:b})})}function*u(){const h=[];for(const d of c){const p=d.key,g=xn(p);for(;h.length<=p.length&&h.length&&p[h.length-1]!=h[h.length-1].group;)yield h.pop();for(let b=0;b<h.length;b++){const y=h[b];y.locSize.size=d.locSize.location-y.locSize.location+d.locSize.size}for(let b=h.length;b<p.length;b++)h.push({group:p[b],locSize:{...d.locSize},depth:h.length,n:0});for(const b of h)b.n+=g.samples.length}for(;h.length;)yield h.pop()}const f=[...u()].sort((h,d)=>h.depth-d.depth).map((h,d)=>({key:{index:d,group:h.group,depth:h.depth,n:h.n,attributeLabel:void 0},locSize:h.locSize}));return{samples:l,summaries:c,groups:f}}function kj(e,t){return t.find(n=>XA(n.locSize,e))}function Tj(e,t){const n=t.specifier,r=e.findDescendantByName(n.view),i=r.getScaleResolution("x");let a;if(td(n.locus)){const f=i.getGenome();if(f)a=f.toContinuous(n.locus.chrom,n.locus.pos);else throw new Error("Encountered a chromosomal locus but no genome is available!")}else a=n.locus;const o=f=>{var h;return(h=r.mark.findDatumAt(f,a))==null?void 0:h[n.field]},[s,c]=Object.entries(r.getEncoding()).find(([f,h])=>"field"in h&&h.field==n.field),l=Ri(s)?r.getScaleResolution(s).getScale():void 0;return{name:n.field,attribute:t,title:$` <em class="attribute">${n.field}</em>
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+
`};function Aj(e,t,n){const r=`attributes["${e}"]`,i={name:`attribute-${e}`,title:{text:e,orient:"bottom",align:"right",baseline:"middle",offset:5,angle:-90+(n.attributeLabelAngle??0),dy:-.5,font:n.attributeLabelFont,fontSize:n.attributeLabelFontSize??11,fontStyle:n.attributeLabelFontStyle,fontWeight:n.attributeLabelFontWeight},visible:t.visible??!0,width:t.width??n.attributeSize??10,transform:[{type:"filter",expr:`datum.${r} != null`}],mark:{type:"rect",xOffset:-.5},encoding:{facetIndex:{field:"indexNumber"},color:{field:r,type:t.type,scale:t.scale}},opacity:1};return t.barScale&&t.type==wb.QUANTITATIVE&&(i.encoding.x={field:`attributes["${e}"]`,type:t.type,scale:t.barScale,axis:null}),i}function Ej(e){return{name:"metadata-sample-name",title:{text:e.labelTitleText??"Sample name",orient:"bottom",anchor:"start",offset:5,font:e.attributeLabelFont,fontSize:e.attributeLabelFontSize??11,fontStyle:e.attributeLabelFontStyle,fontWeight:e.attributeLabelFontWeight},width:e.labelLength??140,mark:{type:"text",baseline:"middle",font:e.labelFont,size:e.labelFontSize??11,fontStyle:e.labelFontStyle,fontWeight:e.labelFontWeight,align:e.labelAlign??"left",flushY:!1},encoding:{facetIndex:{field:"indexNumber"},x:{value:0},x2:{value:1},y:{value:0},y2:{value:1},text:{field:"displayName"}}}}function Sj(e){return e!==""&&!(typeof e=="number"&&isNaN(e))&&e!==null}const M_=Object.freeze({name:"sample",attribute:{type:F_},accessor:e=>e,type:"identifier",scale:void 0});class _j extends Ka{constructor(n,r){super({title:{text:"Groups",orient:"none"},padding:{right:0},width:{step:22},data:{name:null},transform:[{type:"filter",expr:"datum._depth > 0"},{type:"formula",as:"_y1",expr:"datum._index * 2"},{type:"formula",as:"_y2",expr:"datum._index * 2 + 1"},{type:"formula",as:"_title",expr:"datum.title || datum.name"},{type:"formula",as:"_NA",expr:"datum._title === null"},{type:"formula",as:"_title",expr:"datum._title !== null ? datum._title: 'NA'"}],encoding:{x:{field:"_depth",type:"ordinal",scale:{align:0,padding:.2272727},axis:null},y:{field:"_y1",type:"nominal",scale:{type:"ordinal",domain:mi(500)},axis:null},y2:{field:"_y2"}},layer:[{title:"Group",mark:{type:"rect",clip:!0,color:"#e8e8e8",cornerRadiusBottomLeft:14,cornerRadiusTopLeft:14}},{mark:{type:"text",clip:!0,angle:-90,paddingY:5,tooltip:null},encoding:{text:{field:"_title"},opacity:{field:"_NA",type:"nominal",scale:{type:"ordinal",domain:[!1,!0],range:[1,.3]}}}}]},n.context,n,r,"sample-groups");Z(this,cp);this.sampleView=n,this._addBroadcastHandler("layoutComputed",()=>{this.updateRange()}),this.addInteractionEventListener("contextmenu",(i,a)=>{const o=a.uiEvent,s=this.context.getCurrentHover();if(!s)return;const c=s.datum._rawGroup;let l;for(const d of sb(this.sampleView.sampleHierarchy.rootGroup))if(d.at(-1)===c){l=d.slice(1);break}const u=n.actions.removeGroup({path:l.map(d=>d.name)}),f=n.provenance.getActionInfo(u),h=n.provenance.storeHelper.getDispatcher();vb({items:[{label:f.title,icon:f.icon,callback:()=>h(u)}]},o)})}updateRange(){var o,s;const n=(o=this.sampleView.locationManager.getLocations())==null?void 0:o.groups;if(!(n!=null&&n.length))return;const r=((s=this.sampleView)==null?void 0:s.childCoords.height)??0,i=this.getScaleResolution("y"),a=[];for(const c of n)a.push(1-(c.locSize.location+c.locSize.size)/r),a.push(1-c.locSize.location/r);i.getScale().range(a),this.context.glHelper.createRangeTexture(i,!0)}updateGroups(){var o;const n=((o=this.sampleView.locationManager.getLocations())==null?void 0:o.groups)??[],r=this.context.dataFlow.findDataSourceByKey(this);if(!r)return;const i=J(this,cp,rI).call(this),a=n.map(s=>({_index:s.key.index,_depth:s.key.depth,_rawGroup:s.key.group,attribute:i[s.key.depth],name:s.key.group.name,...s.key.group.name!=s.key.group.title?{title:s.key.group.title}:{},n:s.key.n}));r.updateDynamicData(a),this.getScaleResolution("x").reconfigure(),this.getScaleResolution("y").reconfigure(),n.length&&this.updateRange(),xn([...this.getLayoutAncestors()]).visit(s=>Il(s,"size"))}}cp=new WeakSet,rI=function(){const n=document.createElement("div");return[null,...this.sampleView.sampleHierarchy.groupMetadata].map(r=>{if(!r)return"unknown";const i=this.sampleView.compositeAttributeInfoSource.getAttributeInfo(r.attribute).title;return i?Me(i)?i:(Vt(i,n),n.textContent.replace(/\s+/g," ").trim()):"unknown"})};class Cj{constructor(){this.attributeInfoSourcesByType={}}addAttributeInfoSource(t,n){this.attributeInfoSourcesByType[t]=n}getAttributeInfo(t){const n=this.attributeInfoSourcesByType[t.type];if(!n)throw new Error("Cannot find attribute info source for: "+JSON.stringify(t));const r=n(t);if(r)return r;throw new Error("Unknown attribute: "+JSON.stringify(t))}}function Wd(e,t,n){let r=n&&e(n);return i=>{const a=e(i);a!==r&&(t(a,r),r=a)}}class kj{constructor(t){Z(this,Af);Z(this,Ln,0);Z(this,ua,0);Z(this,$o,0);Z(this,Ac,void 0);Z(this,Ec,void 0);Z(this,ui,void 0);Z(this,Sc,void 0);Z(this,It,void 0);Z(this,xf,void 0);le(this,It,t),le(this,xf,t.viewContext.paramBroker.allocateSetter("sampleHeight"))}isCloseup(){return F(this,Ln)===1}resetLocations(){le(this,ui,void 0)}reset(){le(this,Ln,0),this.resetLocations()}handleWheelEvent(t){le(this,ua,Ai(F(this,ua)+t.deltaY,0,F(this,$o)-F(this,It).getHeight()))}togglePeek(t,n,r){if(F(this,Ln)>0&&F(this,Ln)<1||t!==void 0&&t==!!F(this,Ln))return;const i=F(this,It).viewContext,a=F(this,It).getHeight(),o={requestAnimationFrame:s=>i.animator.requestTransition(s),onUpdate:s=>{le(this,Ln,Math.pow(s,2)),F(this,It).onLocationUpdate(),J(this,Af,av).call(this),i.animator.requestRender()},from:F(this,Ln)};if(F(this,Ln)==0){let s;if(r)s=(l=>l.location+l.size/2)(F(this,Sc).samples.find(l=>l.key==r).locSize);else{const c=this.getSummaryAt(n);c&&(s=F(this,Sc).summaries[c.index].locSize.location-(c.location.locSize.location-n))}s?le(this,ua,s-n):le(this,ua,(F(this,$o)-a)/2),F(this,$o)>a?rd({...o,to:1,duration:500,easingFunction:$N}):rd({...o,from:0,to:1,duration:300,easingFunction:l=>(1-Math.pow(l*2-1,2))*.5})}else rd({...o,to:0,duration:400,easingFunction:NN})}getLocations(){if(F(this,ui))return F(this,ui);const t=F(this,It).getHeight();if(!t)return;const n=F(this,It).getSampleHierarchy(),r=ob(n),i=F(this,It).getSummaryHeight(),a=O_(r,{viewHeight:t,groupSpacing:5,summaryHeight:i}),o=O_(r,{sampleHeight:35,groupSpacing:15,summaryHeight:i}),s=()=>-F(this,ua),c=()=>F(this,Ln);le(this,Sc,o),le(this,$o,o.summaries.map(f=>f.locSize.location+f.locSize.size).reduce((f,h)=>Math.max(f,h),0));const l=(f,h)=>{const d=[];for(let p=0;p<f.length;p++){const g=f[p].key;d.push({key:g,locSize:XL(f[p].locSize,KL(h[p].locSize,s),c)})}return d},u=l(a.groups,o.groups);return le(this,ui,{samples:l(a.samples,o.samples),summaries:l(a.summaries,o.summaries),groups:u}),J(this,Af,av).call(this),F(this,ui)}getGroupBackgroundRects(t){const n=this.getLocations().groups,r=n.map(s=>s.key.depth).reduce((s,c)=>Math.max(s,c),0),i=n.filter(s=>s.key.depth==r),a=F(this,It).getSummaryHeight();t=t.flatten();const o=F(this,It).isStickySummaries()&&a>0?t.shrink(new Ct(a,0,0,0)):t;return[...i.values()].map(s=>{const c=()=>{const l=s.locSize.location;return t.y+l+a};return{coords:t.modify({y:c,height:()=>s.locSize.size-a}).intersect(o),clipRect:o}})}updateFacetTexture(){const t=F(this,It).getSampleHierarchy().sampleData;if(!F(this,Ec)){const a=t&&Object.values(t.entities);le(this,Ec,new Float32Array(Math.ceil(a.length*2/4)*4))}const n=F(this,Ec);n.fill(0);const r=t==null?void 0:t.entities;if(r){const a=this.getLocations().samples,o=F(this,It).getHeight();for(const s of a){const c=r[s.key].indexNumber;n[c*2+0]=s.locSize.location/o,n[c*2+1]=s.locSize.size/o}}const i=F(this,It).viewContext.glHelper.gl;le(this,Ac,Dl(i,{internalFormat:i.RG32F,format:i.RG,height:1},n,F(this,Ac)))}getFacetTexture(){return F(this,Ac)}getSummaryAt(t){const n=this.getLocations().summaries,r=n.findIndex(i=>XA(i.locSize,t));return r>=0?{index:r,location:n[r]}:void 0}clipBySummary(t){if(F(this,It).isStickySummaries()){const n=F(this,It).getSummaryHeight();if(n>0)return t.modify({y:()=>t.y+n,height:()=>t.height-n})}return t}}Ln=new WeakMap,ua=new WeakMap,$o=new WeakMap,Ac=new WeakMap,Ec=new WeakMap,ui=new WeakMap,Sc=new WeakMap,It=new WeakMap,xf=new WeakMap,Af=new WeakSet,av=function(){var t;F(this,xf).call(this,((t=F(this,ui).samples[0])==null?void 0:t.locSize.size)??0)};function O_(e,{viewHeight:t=0,sampleHeight:n=0,groupSpacing:r=5,summaryHeight:i=0}){if(!t&&!n)throw new Error("viewHeight or sampleHeight must be provided!");const a=h=>xn(h),o=e.map(h=>({path:h,sampleGroup:a(h),samples:a(h).samples})).filter(h=>h.samples.length),s=n?h=>({px:h.length*n+i,grow:0}):h=>({px:i,grow:h.length}),c=[];Fl(o.map(h=>s(h.samples)),t,{spacing:r}).forEach((h,d)=>{c.push({key:o[d].path,locSize:h})});const l=[];for(const[h,d]of o.entries()){const p={grow:1},g=d.samples;Fl(g.map(b=>p),Math.max(0,c[h].locSize.size-i),{offset:c[h].locSize.location+i}).forEach((b,y)=>{const{size:w,location:A}=b,x=w*.1*pg(15,22,w);b.location=A+x,b.size=w-2*x,l.push({key:g[y],locSize:b})})}function*u(){const h=[];for(const d of c){const p=d.key,g=xn(p);for(;h.length<=p.length&&h.length&&p[h.length-1]!=h[h.length-1].group;)yield h.pop();for(let b=0;b<h.length;b++){const y=h[b];y.locSize.size=d.locSize.location-y.locSize.location+d.locSize.size}for(let b=h.length;b<p.length;b++)h.push({group:p[b],locSize:{...d.locSize},depth:h.length,n:0});for(const b of h)b.n+=g.samples.length}for(;h.length;)yield h.pop()}const f=[...u()].sort((h,d)=>h.depth-d.depth).map((h,d)=>({key:{index:d,group:h.group,depth:h.depth,n:h.n,attributeLabel:void 0},locSize:h.locSize}));return{samples:l,summaries:c,groups:f}}function Tj(e,t){return t.find(n=>XA(n.locSize,e))}function Ij(e,t){const n=t.specifier,r=e.findDescendantByName(n.view),i=r.getScaleResolution("x");let a;if(td(n.locus)){const f=i.getGenome();if(f)a=f.toContinuous(n.locus.chrom,n.locus.pos);else throw new Error("Encountered a chromosomal locus but no genome is available!")}else a=n.locus;const o=f=>{var h;return(h=r.mark.findDatumAt(f,a))==null?void 0:h[n.field]},[s,c]=Object.entries(r.getEncoding()).find(([f,h])=>"field"in h&&h.field==n.field),l=Ri(s)?r.getScaleResolution(s).getScale():void 0;return{name:n.field,attribute:t,title:$` <em class="attribute">${n.field}</em>
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2892
2895
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<span class="viewTitle">(${r.getTitleText()??r.name})</span>
|
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2893
2896
|
${td(n.locus)?$`at
|
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2894
2897
|
<span class="locus"
|
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2895
2898
|
>${lE(n.locus)}</span
|
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2896
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-
>`:$`<span class="scalar">of ${a}</span>`}`,accessor:o,type:"type"in c?c.type:void 0,scale:l}}const L_="VALUE_AT_LOCUS";class xb extends Yn{constructor(n,r,i,a,o,s){super(n,r,i,a,o);Z(this,lp);Z(this,up);Z(this,fp);Z(this,Sf);Z(this,hp);Z(this,dp);Z(this,pp);Z(this,ot,void 0);Z(this,Ht,void 0);Z(this,Ef,-1);Z(this,_c,!1);this.provenance=s,this.spec=n,le(this,_c,n.stickySummaries??!0),this.compositeAttributeInfoSource=new _j,this.childCoords=Zn.ZERO,this.sidebarCoords=Zn.ZERO,this.locationManager=new Cj({getSampleHierarchy:()=>this.sampleHierarchy,getHeight:()=>this.childCoords.height,getSummaryHeight:()=>F(this,ot).summaryViews.getSize().height.px,onLocationUpdate:()=>{this.groupPanel.updateGroups()},viewContext:this.context,isStickySummaries:()=>F(this,_c)}),this.provenance.storeHelper.subscribe(Wd(f=>ab(f).rootGroup,f=>{var h;this.locationManager.reset(),(h=this.groupPanel)==null||h.updateGroups(),this.context.requestLayoutReflow(),this.context.animator.requestRender()})),this.provenance.storeHelper.subscribe(Wd(f=>ab(f).sampleData,f=>{const h=f&&Object.values(f.entities);h&&(this.metadataView.setSamples(h),this.groupPanel.updateGroups())})),this.compositeAttributeInfoSource.addAttributeInfoSource(L_,f=>Tj(this,f)),this._addBroadcastHandler("dataLoaded",()=>J(this,up,aI).call(this)),this._addBroadcastHandler("layout",()=>{this.locationManager.resetLocations()}),this.addInteractionEventListener("mousemove",(f,h)=>{le(this,Ef,h.point.y-this.childCoords.y)}),this.addInteractionEventListener("wheel",(f,h)=>{const d=h.uiEvent;this.locationManager.isCloseup()&&!d.ctrlKey&&(this.locationManager.handleWheelEvent(d),this.groupPanel.updateRange(),this.context.animator.requestRender(),h.uiEvent={type:d.type,deltaX:d.deltaX,preventDefault:d.preventDefault.bind(d)})},!0),r.addKeyboardListener("keydown",f=>{f.code=="KeyE"&&!f.repeat&&J(this,Sf,ov).call(this)}),r.addKeyboardListener("keyup",f=>{f.code=="KeyE"&&this.locationManager.togglePeek(!1)});const c=f=>this.compositeAttributeInfoSource.getAttributeInfo(f),l=MV(c);this.provenance.addReducer(l.name,l.reducer),this.provenance.addActionInfoSource(f=>LV(f,c)),this.actions=l.actions;const u=JG(f=>{var h;return(h=f.sampleData)==null?void 0:h.entities},f=>f&&Object.values(f));this.getSamples=()=>u(this.sampleHierarchy),this.spec.samples.data&&J(this,lp,iI).call(this)}async initializeChildren(){le(this,ot,new Dj(this.context.createView(this.spec.spec,this,this,"sample-facets"),this,0,this.spec.view)),le(this,Ht,new ys({title:"Sidebar",resolve:{scale:{default:"independent"},axis:{default:"independent"}},encoding:{y:null,facetIndex:null},hconcat:[],spacing:0},this.context,this,this,"sample-sidebar")),this.groupPanel=new Sj(this,F(this,Ht)),this.metadataView=new P_(this,F(this,Ht)),F(this,Ht).setChildren([this.groupPanel,this.metadataView]),F(this,ot).view instanceof Yn&&await F(this,ot).view.initializeChildren(),F(this,ot).summaryViews instanceof Yn&&await F(this,ot).summaryViews.initializeChildren(),await F(this,ot).createAxes(),await J(this,pp,lI).call(this),await F(this,ot).summaryViews.createAxes(),await this.groupPanel.initializeChildren(),await this.metadataView.initializeChildren(),F(this,ot).view.addInteractionEventListener("contextmenu",J(this,hp,sI).bind(this))}getOverhang(){let n=F(this,Ht).isConfiguredVisible()?F(this,Ht).getSize().width.px+F(this,Ht).getPadding().horizontalTotal:0;return new Ct(0,0,0,n).add(F(this,ot).getOverhang())}getSize(){return this._cache("size/size2",()=>{const n=super.getSize(),r=a=>a.getSize().addPadding(a.getOverhang()).addPadding(a.getPadding()),i=ZL([F(this,Ht),F(this,ot).view].map(a=>r(a).width));return new Gr(i,n.height)})}*[Symbol.iterator](){yield F(this,Ht),yield*F(this,ot).getChildren()}get sampleHierarchy(){return this.provenance.getPresentState()[Cs]}get leafSamples(){return ob(this.sampleHierarchy).map(r=>r.at(-1)).map(r=>r.samples).flat()}getSampleAt(n){const r=kj(n,this.locationManager.getLocations().samples);if(r)return this.sampleHierarchy.sampleData.entities[r.key]}render(n,r,i={}){if(super.render(n,r,i),!this.isConfiguredVisible())return;this.layoutParent||(r=r.shrink(this.getPadding())),r=r.shrink(F(this,ot).getOverhang()),n.pushView(this,r);const a=Fl([F(this,Ht).isConfiguredVisible()?F(this,Ht).getSize().width:{px:0},{grow:1}],r.width),o=s=>r.modify({x:s.location+r.x,width:s.size});this.sidebarCoords=o(a[0]),this.childCoords=o(a[1]),F(this,Ht).render(n,this.sidebarCoords,i),J(this,fp,oI).call(this,n,this.childCoords,i),n.popView(this)}onBeforeRender(){this.locationManager.updateFacetTexture()}getSampleFacetTexture(){return this.locationManager.getFacetTexture()}makePeekMenuItem(){return{...this.locationManager.isCloseup()?{label:"Close closeup",callback:()=>this.locationManager.togglePeek(!1),icon:M$}:{label:"Open closeup",callback:()=>J(this,Sf,ov).call(this),icon:L$},shortcut:"E"}}findSampleForMouseEvent(n,r){return this.getSampleAt(r.point.y-this.childCoords.y)}propagateInteractionEvent(n){this.handleInteractionEvent(void 0,n,!0),!n.stopped&&(this.childCoords.containsPoint(n.point.x,n.point.y)&&(F(this,ot).view.propagateInteractionEvent(n),jE(n,this.childCoords,r=>J(this,dp,cI).call(this,this.childCoords,F(this,ot).view,r),this.context.getCurrentHover())),this.sidebarCoords.containsPoint(n.point.x,n.point.y)&&F(this,Ht).propagateInteractionEvent(n),!n.stopped&&this.handleInteractionEvent(void 0,n,!1))}getDefaultResolution(n,r){if(r=="axis")return"independent";switch(n){case"x":case"sample":return"shared";default:return"independent"}}}ot=new WeakMap,Ht=new WeakMap,Ef=new WeakMap,_c=new WeakMap,lp=new WeakSet,iI=function(){if(!this.spec.samples.data)throw new Error("SampleView has no explicit sample metadata specified! Cannot load anything.");const{dataSource:n,collector:r}=Xz(CE(this.spec.samples.data,this),new Ij);r.observers.push(a=>{const o=a.getData();this.provenance.storeHelper.dispatch(this.actions.setSamples({samples:o}))});const i="samples "+this.getPathString();this.context.dataFlow.addDataSource(n,i)},up=new WeakSet,aI=function(){if(this.getSamples())return;const n=this.getScaleResolution("sample");if(n){const r=[...n.getDataDomain()].map((i,a)=>({id:i,displayName:i,indexNumber:a,attributes:[]}));this.provenance.storeHelper.dispatch(this.actions.setSamples({samples:r}))}else throw new Error("No explicit sample data nor sample channels found!")},fp=new WeakSet,oI=function(n,r,i={}){var g,b,y,w;const a=F(this,ot),o=a.groupBackground||Object.values(a.axes).length?this.locationManager.getGroupBackgroundRects(this.childCoords):[];for(const{coords:A,clipRect:x}of o){(g=a.groupBackground)==null||g.render(n,A,i);for(const C of Object.values(a.gridLines))C.render(n,A,{...i,clipRect:x})}const s=1/r.height,c=()=>s,l=this.locationManager.clipBySummary(r),u=this.locationManager.getLocations(),f=u.samples.map(A=>({...i,sampleFacetRenderingOptions:{locSize:JL(A.locSize,c)},facetId:[A.key],clipRect:l}));for(const A of f)(b=a.background)==null||b.render(n,r,A),a.view.render(n,r,A),(y=a.backgroundStroke)==null||y.render(n,r,A);for(const{coords:A}of o)(w=a.groupBackgroundStroke)==null||w.render(n,A,i);for(const[A,x]of Object.entries(a.axes))x.render(n,i1(r,A,x));const h=a.summaryViews,d=h.getOverhang().getHorizontal();i={...i,clipRect:r.expand(d)};const p=h.getSize().height.px;for(const[A,x]of u.summaries.entries()){const C=()=>{const I=x.locSize.location;let D=r.y+I;return F(this,_c)?D+Ai(-I,0,x.locSize.size-p):D},_=r.modify({y:C,height:p}).expand(d);h.render(n,_,{...i,facetId:[A]})}},Sf=new WeakSet,ov=function(){var i;const n=F(this,Ef),r=(i=this.getSampleAt(n))==null?void 0:i.id;this.locationManager.togglePeek(void 0,n,r)},hp=new WeakSet,sI=function(n,r){var g,b;const i=r.uiEvent,a=this.childCoords.normalizePoint(r.point.x,r.point.y).x,o=this.findSampleForMouseEvent(n,r),s=F(this,ot).view,c=s.getScaleResolution("x"),l=c.invertToComplex(a),u=ME(this.getLayoutAncestors().at(-1)),f=(g=s.getAxisResolution("x"))==null?void 0:g.getTitle(),h=nU(s).filter(y=>!["sample","x","x2"].includes(y.channel)).filter(y=>["rect","rule"].includes(y.view.getMarkType())).filter(y=>u.has(y.view.name));let d=[this.makePeekMenuItem(),yb,{label:c.type==="locus"?`Locus: ${lE(l)}`:`${f?f+": ":""}${l}`,type:"header"},yb],p="";for(const[y,w]of h.entries()){const A={view:w.view.name,field:w.field,locus:l},x=this.compositeAttributeInfoSource.getAttributeInfo({type:L_,specifier:A}),C=w.view.getTitleText()??w.view.spec.name;C!=p&&(y>0&&d.push({type:"divider"}),d.push({label:C,type:"header"}),p=C);const _=c.getScale(),I="invert"in _&&o?(b=w.view.mark.findDatumAt(o.id,_.invert(a)))==null?void 0:b[w.field]:void 0;d.push({label:w.field,submenu:cb(null,x,I,this)})}vb({items:d},i)},dp=new WeakSet,cI=function(n,r,i){const a=F(this,ot).view.getScaleResolution("x");if(!a||!a.isZoomable())return;const o=n.normalizePoint(i.x,i.y),s=n.normalizePoint(i.x+i.xDelta,i.y+i.yDelta);a.zoom(2**i.zDelta,o.x,s.x-o.x),this.context.animator.requestRender()},pp=new WeakSet,lI=async function(){const n=[];for(const r of F(this,ot).view.getDescendants()){const i=r.spec;if(WU(i))for(const a of i.aggregateSamples){const o=a.transform??[];o.length&&o.at(-1).type!="collect"&&o.push({type:"collect"}),o.push({type:"mergeFacets"}),a.transform=o,a.encoding={...a.encoding??{},sample:null};const s=this.context.createView(a,this,r,"summaryView");s instanceof Yn&&await s.initializeChildren(),s.getFacetFields=c=>{},n.push(s)}}F(this,ot).summaryViews.setChildren(n)};class Ij extends at{constructor(){super(),this.reset()}reset(){this._index=0}handle(t){this._propagate({id:t.sample,displayName:t.displayName||t.sample,indexNumber:this._index++,attributes:Rj(t)})}}function Rj(e){const t=Object.assign({},e);return delete t.sample,delete t.displayName,t}class Dj extends a1{constructor(t,n,r,i){super(t,n,r),this.groupBackground=void 0,this.groupBackgroundStroke=void 0;const a=qE(i);a&&(this.groupBackground=new mt(a,n.context,n,t,"sample-group-background-"+r,{blockEncodingInheritance:!0}));const o=WE(i);o&&(this.groupBackgroundStroke=new mt(o,n.context,n,t,"sample-group-background-stroke-"+r,{blockEncodingInheritance:!0})),this.summaryViews=new ys({configurableVisibility:!1,resolve:{axis:{x:"independent"}},spacing:0,vconcat:[]},n.context,n,n,"sampleSummaries")}*getChildren(){this.groupBackground&&(yield this.groupBackground),this.groupBackgroundStroke&&(yield this.groupBackgroundStroke),yield this.summaryViews,yield*super.getChildren()}}const Bj=(e,t)=>t.some(n=>e instanceof n);let N_,z_;function Fj(){return N_||(N_=[IDBDatabase,IDBObjectStore,IDBIndex,IDBCursor,IDBTransaction])}function Pj(){return z_||(z_=[IDBCursor.prototype.advance,IDBCursor.prototype.continue,IDBCursor.prototype.continuePrimaryKey])}const U_=new WeakMap,Ab=new WeakMap,$_=new WeakMap,Eb=new WeakMap,Sb=new WeakMap;function Mj(e){const t=new Promise((n,r)=>{const i=()=>{e.removeEventListener("success",a),e.removeEventListener("error",o)},a=()=>{n(qi(e.result)),i()},o=()=>{r(e.error),i()};e.addEventListener("success",a),e.addEventListener("error",o)});return t.then(n=>{n instanceof IDBCursor&&U_.set(n,e)}).catch(()=>{}),Sb.set(t,e),t}function Oj(e){if(Ab.has(e))return;const t=new Promise((n,r)=>{const i=()=>{e.removeEventListener("complete",a),e.removeEventListener("error",o),e.removeEventListener("abort",o)},a=()=>{n(),i()},o=()=>{r(e.error||new DOMException("AbortError","AbortError")),i()};e.addEventListener("complete",a),e.addEventListener("error",o),e.addEventListener("abort",o)});Ab.set(e,t)}let _b={get(e,t,n){if(e instanceof IDBTransaction){if(t==="done")return Ab.get(e);if(t==="objectStoreNames")return e.objectStoreNames||$_.get(e);if(t==="store")return n.objectStoreNames[1]?void 0:n.objectStore(n.objectStoreNames[0])}return qi(e[t])},set(e,t,n){return e[t]=n,!0},has(e,t){return e instanceof IDBTransaction&&(t==="done"||t==="store")?!0:t in e}};function Lj(e){_b=e(_b)}function Nj(e){return e===IDBDatabase.prototype.transaction&&!("objectStoreNames"in IDBTransaction.prototype)?function(t,...n){const r=e.call(Cb(this),t,...n);return $_.set(r,t.sort?t.sort():[t]),qi(r)}:Pj().includes(e)?function(...t){return e.apply(Cb(this),t),qi(U_.get(this))}:function(...t){return qi(e.apply(Cb(this),t))}}function zj(e){return typeof e=="function"?Nj(e):(e instanceof IDBTransaction&&Oj(e),Bj(e,Fj())?new Proxy(e,_b):e)}function qi(e){if(e instanceof IDBRequest)return Mj(e);if(Eb.has(e))return Eb.get(e);const t=zj(e);return t!==e&&(Eb.set(e,t),Sb.set(t,e)),t}const Cb=e=>Sb.get(e);function Uj(e,t,{blocked:n,upgrade:r,blocking:i,terminated:a}={}){const o=indexedDB.open(e,t),s=qi(o);return r&&o.addEventListener("upgradeneeded",c=>{r(qi(o.result),c.oldVersion,c.newVersion,qi(o.transaction),c)}),n&&o.addEventListener("blocked",c=>n(c.oldVersion,c.newVersion,c)),s.then(c=>{a&&c.addEventListener("close",()=>a()),i&&c.addEventListener("versionchange",l=>i(l.oldVersion,l.newVersion,l))}).catch(()=>{}),s}const $j=["get","getKey","getAll","getAllKeys","count"],Hj=["put","add","delete","clear"],kb=new Map;function H_(e,t){if(!(e instanceof IDBDatabase&&!(t in e)&&typeof t=="string"))return;if(kb.get(t))return kb.get(t);const n=t.replace(/FromIndex$/,""),r=t!==n,i=Hj.includes(n);if(!(n in(r?IDBIndex:IDBObjectStore).prototype)||!(i||$j.includes(n)))return;const a=async function(o,...s){const c=this.transaction(o,i?"readwrite":"readonly");let l=c.store;return r&&(l=l.index(s.shift())),(await Promise.all([l[n](...s),i&&c.done]))[0]};return kb.set(t,a),a}Lj(e=>({...e,get:(t,n,r)=>H_(t,n)||e.get(t,n,r),has:(t,n)=>!!H_(t,n)||e.has(t,n)}));class G_{isReadonly(){return!0}async put(t,n){this._checkReadonly()}async delete(t){this._checkReadonly()}async getNames(){return[]}async get(t){}_checkReadonly(){if(this.isReadonly())throw new Error("This bookmark")}}const su="bookmarks";class Gj extends G_{constructor(t){super(),this.specId=t,this._db=void 0}async _getDB(){if(!this._db){const t=`GenomeSpy: ${this.specId}`;this._db=Uj(t,1,{upgrade(n,r,i,a){n.createObjectStore(su,{keyPath:"name"})},blocked(){},blocking(){},terminated(){}})}return this._db}isReadonly(){return!1}async put(t,n){const i=(await this._getDB()).transaction(su,"readwrite");try{n?(await i.store.delete(n),await i.store.put(t)):await i.store.put(t),await i.done}catch(a){throw i.abort(),a}}async delete(t){(await this._getDB()).delete(su,t)}async getNames(){return(await this._getDB()).getAllKeys(su)}async get(t){return(await this._getDB()).get(su,t)}}/**
|
|
2899
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+
>`:$`<span class="scalar">of ${a}</span>`}`,accessor:o,type:"type"in c?c.type:void 0,scale:l}}const L_="VALUE_AT_LOCUS";class xb extends Yn{constructor(n,r,i,a,o,s){super(n,r,i,a,o);Z(this,lp);Z(this,up);Z(this,fp);Z(this,Sf);Z(this,hp);Z(this,dp);Z(this,pp);Z(this,ot,void 0);Z(this,Ht,void 0);Z(this,Ef,-1);Z(this,_c,!1);this.provenance=s,this.spec=n,le(this,_c,n.stickySummaries??!0),this.compositeAttributeInfoSource=new Cj,this.childCoords=Zn.ZERO,this.sidebarCoords=Zn.ZERO,this.locationManager=new kj({getSampleHierarchy:()=>this.sampleHierarchy,getHeight:()=>this.childCoords.height,getSummaryHeight:()=>F(this,ot).summaryViews.getSize().height.px,onLocationUpdate:()=>{this.groupPanel.updateGroups()},viewContext:this.context,isStickySummaries:()=>F(this,_c)}),this.provenance.storeHelper.subscribe(Wd(f=>ab(f).rootGroup,f=>{var h;this.locationManager.reset(),(h=this.groupPanel)==null||h.updateGroups(),this.context.requestLayoutReflow(),this.context.animator.requestRender()})),this.provenance.storeHelper.subscribe(Wd(f=>ab(f).sampleData,f=>{const h=f&&Object.values(f.entities);h&&(this.metadataView.setSamples(h),this.groupPanel.updateGroups())})),this.compositeAttributeInfoSource.addAttributeInfoSource(L_,f=>Ij(this,f)),this._addBroadcastHandler("dataLoaded",()=>J(this,up,aI).call(this)),this._addBroadcastHandler("layout",()=>{this.locationManager.resetLocations()}),this.addInteractionEventListener("mousemove",(f,h)=>{le(this,Ef,h.point.y-this.childCoords.y)}),this.addInteractionEventListener("wheel",(f,h)=>{const d=h.uiEvent;this.locationManager.isCloseup()&&!d.ctrlKey&&(this.locationManager.handleWheelEvent(d),this.groupPanel.updateRange(),this.context.animator.requestRender(),h.uiEvent={type:d.type,deltaX:d.deltaX,preventDefault:d.preventDefault.bind(d)})},!0),r.addKeyboardListener("keydown",f=>{f.code=="KeyE"&&!f.repeat&&J(this,Sf,ov).call(this)}),r.addKeyboardListener("keyup",f=>{f.code=="KeyE"&&this.locationManager.togglePeek(!1)});const c=f=>this.compositeAttributeInfoSource.getAttributeInfo(f),l=OV(c);this.provenance.addReducer(l.name,l.reducer),this.provenance.addActionInfoSource(f=>NV(f,c)),this.actions=l.actions;const u=eV(f=>{var h;return(h=f.sampleData)==null?void 0:h.entities},f=>f&&Object.values(f));this.getSamples=()=>u(this.sampleHierarchy),this.spec.samples.data&&J(this,lp,iI).call(this)}async initializeChildren(){le(this,ot,new Bj(this.context.createView(this.spec.spec,this,this,"sample-facets"),this,0,this.spec.view)),le(this,Ht,new ys({title:"Sidebar",resolve:{scale:{default:"independent"},axis:{default:"independent"}},encoding:{y:null,facetIndex:null},hconcat:[],spacing:0},this.context,this,this,"sample-sidebar")),this.groupPanel=new _j(this,F(this,Ht)),this.metadataView=new P_(this,F(this,Ht)),F(this,Ht).setChildren([this.groupPanel,this.metadataView]),F(this,ot).view instanceof Yn&&await F(this,ot).view.initializeChildren(),F(this,ot).summaryViews instanceof Yn&&await F(this,ot).summaryViews.initializeChildren(),await F(this,ot).createAxes(),await J(this,pp,lI).call(this),await F(this,ot).summaryViews.createAxes(),await this.groupPanel.initializeChildren(),await this.metadataView.initializeChildren(),F(this,ot).view.addInteractionEventListener("contextmenu",J(this,hp,sI).bind(this))}getOverhang(){let n=F(this,Ht).isConfiguredVisible()?F(this,Ht).getSize().width.px+F(this,Ht).getPadding().horizontalTotal:0;return new Ct(0,0,0,n).add(F(this,ot).getOverhang())}getSize(){return this._cache("size/size2",()=>{const n=super.getSize(),r=a=>a.getSize().addPadding(a.getOverhang()).addPadding(a.getPadding()),i=ZL([F(this,Ht),F(this,ot).view].map(a=>r(a).width));return new Gr(i,n.height)})}*[Symbol.iterator](){yield F(this,Ht),yield*F(this,ot).getChildren()}get sampleHierarchy(){return this.provenance.getPresentState()[Cs]}get leafSamples(){return ob(this.sampleHierarchy).map(r=>r.at(-1)).map(r=>r.samples).flat()}getSampleAt(n){const r=Tj(n,this.locationManager.getLocations().samples);if(r)return this.sampleHierarchy.sampleData.entities[r.key]}render(n,r,i={}){if(super.render(n,r,i),!this.isConfiguredVisible())return;this.layoutParent||(r=r.shrink(this.getPadding())),r=r.shrink(F(this,ot).getOverhang()),n.pushView(this,r);const a=Fl([F(this,Ht).isConfiguredVisible()?F(this,Ht).getSize().width:{px:0},{grow:1}],r.width),o=s=>r.modify({x:s.location+r.x,width:s.size});this.sidebarCoords=o(a[0]),this.childCoords=o(a[1]),F(this,Ht).render(n,this.sidebarCoords,i),J(this,fp,oI).call(this,n,this.childCoords,i),n.popView(this)}onBeforeRender(){this.locationManager.updateFacetTexture()}getSampleFacetTexture(){return this.locationManager.getFacetTexture()}makePeekMenuItem(){return{...this.locationManager.isCloseup()?{label:"Close closeup",callback:()=>this.locationManager.togglePeek(!1),icon:O$}:{label:"Open closeup",callback:()=>J(this,Sf,ov).call(this),icon:N$},shortcut:"E"}}findSampleForMouseEvent(n,r){return this.getSampleAt(r.point.y-this.childCoords.y)}propagateInteractionEvent(n){this.handleInteractionEvent(void 0,n,!0),!n.stopped&&(this.childCoords.containsPoint(n.point.x,n.point.y)&&(F(this,ot).view.propagateInteractionEvent(n),jE(n,this.childCoords,r=>J(this,dp,cI).call(this,this.childCoords,F(this,ot).view,r),this.context.getCurrentHover())),this.sidebarCoords.containsPoint(n.point.x,n.point.y)&&F(this,Ht).propagateInteractionEvent(n),!n.stopped&&this.handleInteractionEvent(void 0,n,!1))}getDefaultResolution(n,r){if(r=="axis")return"independent";switch(n){case"x":case"sample":return"shared";default:return"independent"}}}ot=new WeakMap,Ht=new WeakMap,Ef=new WeakMap,_c=new WeakMap,lp=new WeakSet,iI=function(){if(!this.spec.samples.data)throw new Error("SampleView has no explicit sample metadata specified! Cannot load anything.");const{dataSource:n,collector:r}=Kz(CE(this.spec.samples.data,this),new Rj);r.observers.push(a=>{const o=a.getData();this.provenance.storeHelper.dispatch(this.actions.setSamples({samples:o}))});const i="samples "+this.getPathString();this.context.dataFlow.addDataSource(n,i)},up=new WeakSet,aI=function(){if(this.getSamples())return;const n=this.getScaleResolution("sample");if(n){const r=[...n.getDataDomain()].map((i,a)=>({id:i,displayName:i,indexNumber:a,attributes:[]}));this.provenance.storeHelper.dispatch(this.actions.setSamples({samples:r}))}else throw new Error("No explicit sample data nor sample channels found!")},fp=new WeakSet,oI=function(n,r,i={}){var g,b,y,w;const a=F(this,ot),o=a.groupBackground||Object.values(a.axes).length?this.locationManager.getGroupBackgroundRects(this.childCoords):[];for(const{coords:A,clipRect:x}of o){(g=a.groupBackground)==null||g.render(n,A,i);for(const C of Object.values(a.gridLines))C.render(n,A,{...i,clipRect:x})}const s=1/r.height,c=()=>s,l=this.locationManager.clipBySummary(r),u=this.locationManager.getLocations(),f=u.samples.map(A=>({...i,sampleFacetRenderingOptions:{locSize:JL(A.locSize,c)},facetId:[A.key],clipRect:l}));for(const A of f)(b=a.background)==null||b.render(n,r,A),a.view.render(n,r,A),(y=a.backgroundStroke)==null||y.render(n,r,A);for(const{coords:A}of o)(w=a.groupBackgroundStroke)==null||w.render(n,A,i);for(const[A,x]of Object.entries(a.axes))x.render(n,i1(r,A,x));const h=a.summaryViews,d=h.getOverhang().getHorizontal();i={...i,clipRect:r.expand(d)};const p=h.getSize().height.px;for(const[A,x]of u.summaries.entries()){const C=()=>{const I=x.locSize.location;let D=r.y+I;return F(this,_c)?D+Ai(-I,0,x.locSize.size-p):D},_=r.modify({y:C,height:p}).expand(d);h.render(n,_,{...i,facetId:[A]})}},Sf=new WeakSet,ov=function(){var i;const n=F(this,Ef),r=(i=this.getSampleAt(n))==null?void 0:i.id;this.locationManager.togglePeek(void 0,n,r)},hp=new WeakSet,sI=function(n,r){var g,b;const i=r.uiEvent,a=this.childCoords.normalizePoint(r.point.x,r.point.y).x,o=this.findSampleForMouseEvent(n,r),s=F(this,ot).view,c=s.getScaleResolution("x"),l=c.invertToComplex(a),u=ME(this.getLayoutAncestors().at(-1)),f=(g=s.getAxisResolution("x"))==null?void 0:g.getTitle(),h=rU(s).filter(y=>!["sample","x","x2"].includes(y.channel)).filter(y=>["rect","rule"].includes(y.view.getMarkType())).filter(y=>u.has(y.view.name));let d=[this.makePeekMenuItem(),yb,{label:c.type==="locus"?`Locus: ${lE(l)}`:`${f?f+": ":""}${l}`,type:"header"},yb],p="";for(const[y,w]of h.entries()){const A={view:w.view.name,field:w.field,locus:l},x=this.compositeAttributeInfoSource.getAttributeInfo({type:L_,specifier:A}),C=w.view.getTitleText()??w.view.spec.name;C!=p&&(y>0&&d.push({type:"divider"}),d.push({label:C,type:"header"}),p=C);const _=c.getScale(),I="invert"in _&&o?(b=w.view.mark.findDatumAt(o.id,_.invert(a)))==null?void 0:b[w.field]:void 0;d.push({label:w.field,submenu:cb(null,x,I,this)})}vb({items:d},i)},dp=new WeakSet,cI=function(n,r,i){const a=F(this,ot).view.getScaleResolution("x");if(!a||!a.isZoomable())return;const o=n.normalizePoint(i.x,i.y),s=n.normalizePoint(i.x+i.xDelta,i.y+i.yDelta);a.zoom(2**i.zDelta,o.x,s.x-o.x),this.context.animator.requestRender()},pp=new WeakSet,lI=async function(){const n=[];for(const r of F(this,ot).view.getDescendants()){const i=r.spec;if(YU(i))for(const a of i.aggregateSamples){const o=a.transform??[];o.length&&o.at(-1).type!="collect"&&o.push({type:"collect"}),o.push({type:"mergeFacets"}),a.transform=o,a.encoding={...a.encoding??{},sample:null};const s=this.context.createView(a,this,r,"summaryView");s instanceof Yn&&await s.initializeChildren(),s.getFacetFields=c=>{},n.push(s)}}F(this,ot).summaryViews.setChildren(n)};class Rj extends at{constructor(){super(),this.reset()}reset(){this._index=0}handle(t){this._propagate({id:t.sample,displayName:t.displayName||t.sample,indexNumber:this._index++,attributes:Dj(t)})}}function Dj(e){const t=Object.assign({},e);return delete t.sample,delete t.displayName,t}class Bj extends a1{constructor(t,n,r,i){super(t,n,r),this.groupBackground=void 0,this.groupBackgroundStroke=void 0;const a=qE(i);a&&(this.groupBackground=new mt(a,n.context,n,t,"sample-group-background-"+r,{blockEncodingInheritance:!0}));const o=WE(i);o&&(this.groupBackgroundStroke=new mt(o,n.context,n,t,"sample-group-background-stroke-"+r,{blockEncodingInheritance:!0})),this.summaryViews=new ys({configurableVisibility:!1,resolve:{axis:{x:"independent"}},spacing:0,vconcat:[]},n.context,n,n,"sampleSummaries")}*getChildren(){this.groupBackground&&(yield this.groupBackground),this.groupBackgroundStroke&&(yield this.groupBackgroundStroke),yield this.summaryViews,yield*super.getChildren()}}const Fj=(e,t)=>t.some(n=>e instanceof n);let N_,z_;function Pj(){return N_||(N_=[IDBDatabase,IDBObjectStore,IDBIndex,IDBCursor,IDBTransaction])}function Mj(){return z_||(z_=[IDBCursor.prototype.advance,IDBCursor.prototype.continue,IDBCursor.prototype.continuePrimaryKey])}const U_=new WeakMap,Ab=new WeakMap,$_=new WeakMap,Eb=new WeakMap,Sb=new WeakMap;function Oj(e){const t=new Promise((n,r)=>{const i=()=>{e.removeEventListener("success",a),e.removeEventListener("error",o)},a=()=>{n(qi(e.result)),i()},o=()=>{r(e.error),i()};e.addEventListener("success",a),e.addEventListener("error",o)});return t.then(n=>{n instanceof IDBCursor&&U_.set(n,e)}).catch(()=>{}),Sb.set(t,e),t}function Lj(e){if(Ab.has(e))return;const t=new Promise((n,r)=>{const i=()=>{e.removeEventListener("complete",a),e.removeEventListener("error",o),e.removeEventListener("abort",o)},a=()=>{n(),i()},o=()=>{r(e.error||new DOMException("AbortError","AbortError")),i()};e.addEventListener("complete",a),e.addEventListener("error",o),e.addEventListener("abort",o)});Ab.set(e,t)}let _b={get(e,t,n){if(e instanceof IDBTransaction){if(t==="done")return Ab.get(e);if(t==="objectStoreNames")return e.objectStoreNames||$_.get(e);if(t==="store")return n.objectStoreNames[1]?void 0:n.objectStore(n.objectStoreNames[0])}return qi(e[t])},set(e,t,n){return e[t]=n,!0},has(e,t){return e instanceof IDBTransaction&&(t==="done"||t==="store")?!0:t in e}};function Nj(e){_b=e(_b)}function zj(e){return e===IDBDatabase.prototype.transaction&&!("objectStoreNames"in IDBTransaction.prototype)?function(t,...n){const r=e.call(Cb(this),t,...n);return $_.set(r,t.sort?t.sort():[t]),qi(r)}:Mj().includes(e)?function(...t){return e.apply(Cb(this),t),qi(U_.get(this))}:function(...t){return qi(e.apply(Cb(this),t))}}function Uj(e){return typeof e=="function"?zj(e):(e instanceof IDBTransaction&&Lj(e),Fj(e,Pj())?new Proxy(e,_b):e)}function qi(e){if(e instanceof IDBRequest)return Oj(e);if(Eb.has(e))return Eb.get(e);const t=Uj(e);return t!==e&&(Eb.set(e,t),Sb.set(t,e)),t}const Cb=e=>Sb.get(e);function $j(e,t,{blocked:n,upgrade:r,blocking:i,terminated:a}={}){const o=indexedDB.open(e,t),s=qi(o);return r&&o.addEventListener("upgradeneeded",c=>{r(qi(o.result),c.oldVersion,c.newVersion,qi(o.transaction),c)}),n&&o.addEventListener("blocked",c=>n(c.oldVersion,c.newVersion,c)),s.then(c=>{a&&c.addEventListener("close",()=>a()),i&&c.addEventListener("versionchange",l=>i(l.oldVersion,l.newVersion,l))}).catch(()=>{}),s}const Hj=["get","getKey","getAll","getAllKeys","count"],Gj=["put","add","delete","clear"],kb=new Map;function H_(e,t){if(!(e instanceof IDBDatabase&&!(t in e)&&typeof t=="string"))return;if(kb.get(t))return kb.get(t);const n=t.replace(/FromIndex$/,""),r=t!==n,i=Gj.includes(n);if(!(n in(r?IDBIndex:IDBObjectStore).prototype)||!(i||Hj.includes(n)))return;const a=async function(o,...s){const c=this.transaction(o,i?"readwrite":"readonly");let l=c.store;return r&&(l=l.index(s.shift())),(await Promise.all([l[n](...s),i&&c.done]))[0]};return kb.set(t,a),a}Nj(e=>({...e,get:(t,n,r)=>H_(t,n)||e.get(t,n,r),has:(t,n)=>!!H_(t,n)||e.has(t,n)}));class G_{isReadonly(){return!0}async put(t,n){this._checkReadonly()}async delete(t){this._checkReadonly()}async getNames(){return[]}async get(t){}_checkReadonly(){if(this.isReadonly())throw new Error("This bookmark")}}const su="bookmarks";class Vj extends G_{constructor(t){super(),this.specId=t,this._db=void 0}async _getDB(){if(!this._db){const t=`GenomeSpy: ${this.specId}`;this._db=$j(t,1,{upgrade(n,r,i,a){n.createObjectStore(su,{keyPath:"name"})},blocked(){},blocking(){},terminated(){}})}return this._db}isReadonly(){return!1}async put(t,n){const i=(await this._getDB()).transaction(su,"readwrite");try{n?(await i.store.delete(n),await i.store.put(t)):await i.store.put(t),await i.done}catch(a){throw i.abort(),a}}async delete(t){(await this._getDB()).delete(su,t)}async getNames(){return(await this._getDB()).getAllKeys(su)}async get(t){return(await this._getDB()).get(su,t)}}/**
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* @license
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* Copyright 2017 Google LLC
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* SPDX-License-Identifier: BSD-3-Clause
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*/const cu=(e,t)=>{var r;const n=e._$AN;if(n===void 0)return!1;for(const i of n)(r=i._$AO)==null||r.call(i,t,!1),cu(i,t);return!0},Yd=e=>{let t,n;do{if((t=e._$AM)===void 0)break;n=t._$AN,n.delete(e),e=t}while((n==null?void 0:n.size)===0)},V_=e=>{for(let t;t=e._$AM;e=t){let n=t._$AN;if(n===void 0)t._$AN=n=new Set;else if(n.has(e))break;n.add(e),
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+
*/const cu=(e,t)=>{var r;const n=e._$AN;if(n===void 0)return!1;for(const i of n)(r=i._$AO)==null||r.call(i,t,!1),cu(i,t);return!0},Yd=e=>{let t,n;do{if((t=e._$AM)===void 0)break;n=t._$AN,n.delete(e),e=t}while((n==null?void 0:n.size)===0)},V_=e=>{for(let t;t=e._$AM;e=t){let n=t._$AN;if(n===void 0)t._$AN=n=new Set;else if(n.has(e))break;n.add(e),Wj(t)}};function jj(e){this._$AN!==void 0?(Yd(this),this._$AM=e,V_(this)):this._$AM=e}function qj(e,t=!1,n=0){const r=this._$AH,i=this._$AN;if(i!==void 0&&i.size!==0)if(t)if(Array.isArray(r))for(let a=n;a<r.length;a++)cu(r[a],!1),Yd(r[a]);else r!=null&&(cu(r,!1),Yd(r));else cu(this,e)}const Wj=e=>{e.type==cr.CHILD&&(e._$AP??(e._$AP=qj),e._$AQ??(e._$AQ=jj))};class j_ extends Zo{constructor(){super(...arguments),this._$AN=void 0}_$AT(t,n,r){super._$AT(t,n,r),V_(this),this.isConnected=t._$AU}_$AO(t,n=!0){var r,i;t!==this.isConnected&&(this.isConnected=t,t?(r=this.reconnected)==null||r.call(this):(i=this.disconnected)==null||i.call(this)),n&&(cu(this,t),Yd(this))}setValue(t){if(cS(this._$Ct))this._$Ct._$AI(t,this);else{const n=[...this._$Ct._$AH];n[this._$Ci]=t,this._$Ct._$AI(n,this,0)}}disconnected(){}reconnected(){}}/**
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* @license
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* Copyright 2020 Google LLC
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* SPDX-License-Identifier: BSD-3-Clause
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*/const q_=()=>new
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+
*/const q_=()=>new Yj;let Yj=class{};const Tb=new WeakMap,W_=Da(class extends j_{render(e){return ue}update(e,[t]){var r;const n=t!==this.G;return n&&this.G!==void 0&&this.ot(void 0),(n||this.rt!==this.lt)&&(this.G=t,this.ct=(r=e.options)==null?void 0:r.host,this.ot(this.lt=e.element)),ue}ot(e){if(typeof this.G=="function"){const t=this.ct??globalThis;let n=Tb.get(t);n===void 0&&(n=new WeakMap,Tb.set(t,n)),n.get(this.G)!==void 0&&this.G.call(this.ct,void 0),n.set(this.G,e),e!==void 0&&this.G.call(this.ct,e)}else this.G.value=e}get rt(){var e,t;return typeof this.G=="function"?(e=Tb.get(this.ct??globalThis))==null?void 0:e.get(this.G):(t=this.G)==null?void 0:t.value}disconnected(){this.rt===this.lt&&this.ot(void 0)}reconnected(){this.ot(this.lt)}});/**
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* @license
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* Copyright 2018 Google LLC
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* SPDX-License-Identifier: BSD-3-Clause
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-
*/const
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+
*/const Zj={},Qj=Da(class extends Zo{constructor(){super(...arguments),this.nt=Zj}render(e,t){return t()}update(e,[t,n]){if(Array.isArray(t)){if(Array.isArray(this.nt)&&this.nt.length===t.length&&t.every((r,i)=>r===this.nt[i]))return Dt}else if(this.nt===t)return Dt;return this.nt=Array.isArray(t)?Array.from(t):t,this.render(t,n)}});class Xj extends br{constructor(){super(),this.inputRef=q_(),this.app=void 0,this.getDefaultValue=()=>"",this._keyListener=this._onKeyDown.bind(this),this._documentClickListener=t=>{var n;t.target!==this._inputField&&((n=this._inputField)==null||n.blur())},this._focused=!1}get genomeSpy(){return this.app.genomeSpy}get _inputField(){return this.inputRef.value}static get properties(){return{app:{type:Object}}}connectedCallback(){super.connectedCallback(),this._initializeGenome(),document.addEventListener("keydown",this._keyListener),document.addEventListener("click",this._documentClickListener)}disconnectedCallback(){super.disconnectedCallback(),document.removeEventListener("keydown",this._keyListener),document.removeEventListener("click",this._documentClickListener)}createRenderRoot(){return this}_onKeyDown(t){switch(t.code){case"KeyF":t.metaKey||t.altKey||t.ctrlKey||(t.preventDefault(),this.inputRef.value.focus());break}}_initializeGenome(){const t=Y_(this.genomeSpy.viewRoot);t&&(this._genomeResolution=t,this._genome=this.genomeSpy.genomeStore.getGenome(),this.getDefaultValue=()=>this._genome.formatInterval(t.getDomain()),t.addEventListener("domain",bs(()=>this.requestUpdate(),60,!1)))}async searchViews(t){var r;const n=new Intl.Collator("en",{usage:"search",sensitivity:"base"});for(const i of this.genomeSpy.getSearchableViews()){const a=i.getAccessor("search"),o=i.getAccessor("x"),s=i.getAccessor("x2"),c=i.getScaleResolution("x");if(!(!o||!s||!(c!=null&&c.isZoomable()))){for(const l of((r=i.getCollector())==null?void 0:r.getData())??[])if(n.compare(a(l),t)===0){const u=xp([o(l),s(l)],null,1.2);return await c.zoomTo(u),!0}}}return!1}async search(t){await(async()=>{if(this._genomeResolution&&this._genome){const r=this._genome.parseInterval(t);if(r){this._genomeResolution.zoomTo(r);return}if(await this.searchViews(t))return;this.genomeSpy.viewRoot.visit(i=>{i instanceof P_&&i.handleVerboseCommand(t)})}})(),this._inputField.value=this.getDefaultValue(),this.requestUpdate()}_onSearchHelpClicked(t){const n=t.target;n.tagName=="LI"&&this._doExampleSearch(n.innerText)}_onSearchFocused(t){const n=t.target;switch(t.type){case"focus":this._focused=!0,n.select();break;case"blur":this._focused=!1;break}}_onSearchKeyDown(t){const n=t.target;t.code=="Enter"?(t.preventDefault(),this.search(n.value).then(()=>{n.focus(),n.select()}).catch(r=>{console.log(r),alert(r)})):t.code=="Escape"?n.blur():t.stopPropagation()}_doExampleSearch(t){Kj(t,this._inputField).then(()=>{this._inputField.blur(),this.search(t)})}_getSearchHelp(){var r,i;const t=[];t.push($`
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<p>Focus to a specific range. Examples:</p>
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<ul>
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<!-- TODO: Display only when using a genomic coordinate system-->
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@@ -2940,13 +2943,13 @@ svg:not(:root).svg-inline--fa, svg:not(:host).svg-inline--fa {
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@blur=${this._onSearchFocused}
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${W_(this.inputRef)}
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/>
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${
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${Qj([123],()=>this._getSearchHelp())}
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</div>
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-
`}}customElements.define("genome-spy-search-field",
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*/class rq{constructor(t){this.G=t}disconnect(){this.G=void 0}reconnect(t){this.G=t}deref(){return this.G}}let iq=class{constructor(){this.Y=void 0,this.Z=void 0}get(){return this.Y}pause(){this.Y??(this.Y=new Promise(t=>this.Z=t))}resume(){var t;(t=this.Z)==null||t.call(this),this.Y=this.Z=void 0}};/**
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f=[],h=4,d=4,p=3,g="",b=[],y,w,A,x,C,_,I,D={val:u(0),position:l,index:1};for(y=0;y<3;y+=1)f[y]=y;for(A=0,C=Math.pow(2,2),_=1;_!=C;)x=D.val&D.position,D.position>>=1,D.position==0&&(D.position=l,D.val=u(D.index++)),A|=(x>0?1:0)*_,_<<=1;switch(A){case 0:for(A=0,C=Math.pow(2,8),_=1;_!=C;)x=D.val&D.position,D.position>>=1,D.position==0&&(D.position=l,D.val=u(D.index++)),A|=(x>0?1:0)*_,_<<=1;I=n(A);break;case 1:for(A=0,C=Math.pow(2,16),_=1;_!=C;)x=D.val&D.position,D.position>>=1,D.position==0&&(D.position=l,D.val=u(D.index++)),A|=(x>0?1:0)*_,_<<=1;I=n(A);break;case 2:return""}for(f[3]=I,w=I,b.push(I);;){if(D.index>c)return"";for(A=0,C=Math.pow(2,p),_=1;_!=C;)x=D.val&D.position,D.position>>=1,D.position==0&&(D.position=l,D.val=u(D.index++)),A|=(x>0?1:0)*_,_<<=1;switch(I=A){case 0:for(A=0,C=Math.pow(2,8),_=1;_!=C;)x=D.val&D.position,D.position>>=1,D.position==0&&(D.position=l,D.val=u(D.index++)),A|=(x>0?1:0)*_,_<<=1;f[d++]=n(A),I=d-1,h--;break;case 1:for(A=0,C=Math.pow(2,16),_=1;_!=C;)x=D.val&D.position,D.position>>=1,D.position==0&&(D.position=l,D.val=u(D.index++)),A|=(x>0?1:0)*_,_<<=1;f[d++]=n(A),I=d-1,h--;break;case 2:return b.join("")}if(h==0&&(h=Math.pow(2,p),p++),f[I])g=f[I];else if(I===d)g=w+w.charAt(0);else return null;b.push(g),f[d++]=w+g.charAt(0),h--,w=g,h==0&&(h=Math.pow(2,p),p++)}}};return s}();e!=null&&(e.exports=t)}(Fb);var i6=Fb.exports;function uq(){const e=typeof process<"u"?require("util").TextEncoder:TextEncoder;return new e}let a6;function fq(){let e,t=[];for(let n=0;n<256;n++){e=n;for(let r=0;r<8;r++)e=e&1?3988292384^e>>>1:e>>>1;t[n]=e}return t}function hq(e){a6??(a6=fq());let t=-1;const n=uq().encode(e);for(let r=0;r<n.length;r++)t=t>>>8^a6[(t^n[r])&255];return(t^-1)>>>0}function o6(e){return("00000000"+hq(e).toString(16)).slice(-8)}function s6(e){const t=i6.compressToEncodedURIComponent(JSON.stringify(e));return"#"+t+o6(t)}function dq(e){if(!e||e.length<10)throw new Error("The state string in the URL is too short.");const t=e.slice(1,-8),n=e.slice(-8);if(o6(t)!==n)throw new Error("The state string in the URL is corrupted.");return JSON.parse(i6.decompressFromEncodedURIComponent(t))}let ho;function pq(e){for(const t of e.genomeSpy.getNamedScaleResolutions().values())t.isZoomable()&&t.resetZoom();e.storeHelper.dispatch([...e.provenance.isUndoable()?[lo.jumpToPast(0)]:[],Ts.actions.restoreDefaultVisibilities()])}async function Pb(e,t){try{e.actions&&t.provenance.dispatchBookmark(e.actions),t.storeHelper.dispatch(Ts.actions.setViewSettings(e.viewSettings));const n=[];for(const[r,i]of Object.entries(e.scaleDomains??{})){const a=t.genomeSpy.getNamedScaleResolutions().get(r);a?n.push(a.zoomTo(i)):console.warn(`Cannot restore scale domain. Unknown name: ${r}`)}await Promise.all(n)}catch(n){console.error(n),dn($`<p>Cannot restore the state:</p>
|
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<p>${n}</p>`),t.provenance.activateState(0)}}async function fu(e,t,n={}){await Pb(e,t),(ho||e.notes||n.mode=="shared"&&(e.name||e.notes))&&await gq(e,t,n)}async function gq(e,t,n={}){ho??(ho=ao("tour",t.appContainer)),await mq(e,t,n)}async function mq(e,t,n){const r=n.database,i=r?await r.getNames():[],a=i.indexOf(e.name),o=r?` ${a+1} of ${i.length}`:"",s=`${n.mode=="shared"?"Shared bookmark":"Bookmark"}${o}: ${e.name??"Unnamed"}`,c=e.notes?sq(e.notes,{baseUrl:t.genomeSpy.spec.baseUrl}):$`<span class="no-notes">No notes provided</span>`,l=async()=>{if(ho==null||ho.close(),ho=void 0,n.mode=="tour"){const g=n.afterTourBookmark;if(typeof g=="string"){const b=await n.database.get(g);if(!b)throw new Error(`No such bookmark: ${g}`);Pb(b,t)}else g===null||pq(t)}},u=async g=>{const b=await r.get(i[g]);fu(b,t,n),t.appContainer.querySelector("canvas").focus()},f=async()=>{if(await Mb(t.localBookmarkDatabase,e,"add"))try{await t.localBookmarkDatabase.put(e)}catch(g){console.warn(g),dn(`Cannot import bookmark: ${g}`)}},h=$` <button class="btn" @click=${l}>
|
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${n.mode=="tour"?"End tour":"Close"}
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</button>
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${n.mode=="shared"&&t.localBookmarkDatabase?$`
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@click=${()=>u(a-1)}
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?disabled=${a<=0}
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>
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${Ue(
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${Ue(k$).node[0]} Previous
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</button>
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<button
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class="btn"
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@click=${()=>u(a+1)}
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?disabled=${a>=i.length-1}
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>
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Next ${Ue(
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Next ${Ue(f$).node[0]}
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</button>`:ue}`,p=$`
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<button title="Collapse" class="btn collapse" @click=${g=>g.target.closest(".gs-modal").classList.toggle("collapsed")}>
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${Ue(
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${Ue(P$).node[0]}
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</button>
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<div class="modal-title">${s}</div>
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<div class="modal-body markdown" style="max-width: 600px">
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<div class="modal-buttons">${h}</div>
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`;Vt(p,ho.content)}function c6(e,t){const n=JSON.stringify(e,void 0,2),r=window.location,i=r.origin+r.pathname+r.search+(t?"#bookmark:"+e.name.replaceAll(" ","-"):s6(e));dn($`
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<ul class="tabs" @click=${
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<ul class="tabs" @click=${cq}>
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<li class="active-tab"><button>URL</button></li>
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<li><button>JSON</button></li>
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@@ -3090,7 +3093,7 @@ svg:not(:root).svg-inline--fa, svg:not(:host).svg-inline--fa {
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type="text"
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.value=${i}
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/>
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<button @click=${o=>navigator.clipboard.writeText(i).then(()=>o.target.dispatchEvent(
|
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+
<button @click=${o=>navigator.clipboard.writeText(i).then(()=>o.target.dispatchEvent(EG())).catch(()=>dn("Failed to copy!"))}>Copy</button>
|
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</div>
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<small
|
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>The bookmark URL contains all the bookmarked data,
|
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@@ -3115,7 +3118,7 @@ ${n}</textarea
|
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<div class="modal-body" style="width: 500px">
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<div class="gs-alert warning">
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${Ue(
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${Ue(d$).node[0]} The current
|
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visualization state will be updated to the bookmark
|
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you are editing.
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@@ -3173,7 +3176,7 @@ ${n}</textarea
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`,a=t.name,o=()=>!!t.name,s=ao();return new Promise(c=>{const l=()=>{s.close(),c(!1)},u=async()=>{if(!o()){dn("Name is missing!",{title:"Error"});return}let h=!0;e&&!(n&&t.name==a)&&await e.get(t.name)&&(h=await dn($`A bookmark with the name
|
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<em>${t.name}</em> already exists. It will be
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overwritten.`,{title:"Bookmark already exists",cancelButton:!0})),h&&(s.close(),c(!0))},f=()=>{s.close(),c(!0)};Vt(i(l,n=="share"?f:u),s.content),s.content.querySelector("#bookmark-title").focus()})}function l6(e){if(e!==void 0&&(e=e.trim(),e.length))return e}class
|
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overwritten.`,{title:"Bookmark already exists",cancelButton:!0})),h&&(s.close(),c(!0))},f=()=>{s.close(),c(!0)};Vt(i(l,n=="share"?f:u),s.content),s.content.querySelector("#bookmark-title").focus()})}function l6(e){if(e!==void 0&&(e=e.trim(),e.length))return e}class bq extends br{constructor(){super(),this.app=void 0}connectedCallback(){super.connectedCallback(),this.dispatchEvent(X_("app",t=>{this.app=t}))}createRenderRoot(){return this}_createBookmarkWithCurrentState(){const t={name:void 0,timestamp:Date.now(),actions:this.app.provenance.getBookmarkableActionHistory(),scaleDomains:{}},n=this.app.storeHelper.state.viewSettings;Object.keys(n.visibilities).length&&(t.viewSettings=n);for(const[r,i]of this.app.genomeSpy.getNamedScaleResolutions().entries())i.isZoomable()&&(t.scaleDomains[r]=i.getComplexDomain());return t}async _shareCurrentState(){const t=this._createBookmarkWithCurrentState();await Mb(void 0,t,"share")&&c6(t,!1)}async _addBookmark(t,n){const r=n?await t.get(n):void 0,i=!!r,a=this._createBookmarkWithCurrentState();if(a.name??(a.name=r==null?void 0:r.name),a.notes??(a.notes=r==null?void 0:r.notes),await Mb(t,a,i?"edit":"add"))try{await t.put(a,r==null?void 0:r.name),this.requestUpdate()}catch(o){dn(`${o}`,{title:"Cannot save the bookmark!"})}}async _loadBookmark(t,n){const r=await t.get(n);r&&fu(r,this.app,{database:t})}_createContextMenu(t,n,r){r.stopPropagation();const i=r.target.closest("li"),a=()=>dn($`The bookmark <em>${n}</em> will be deleted.`,{title:"Are you sure?",cancelButton:!0}).then(async c=>{c&&(await t.delete(n),this.requestUpdate())}),o=[],s=t==this.app.globalBookmarkDatabase;s||(o.push({label:"Edit and replace...",icon:w$,callback:()=>this._addBookmark(t,n)}),o.push({label:"Delete",icon:s4,callback:a})),o.push({label:"Share...",icon:h1,callback:async()=>c6(await t.get(n),s)}),B_({items:o},i,"right-start")}async _makeBookmarkMenuItems(t,n){const i=(await t.getNames()).map(a=>({label:a,callback:()=>this._loadBookmark(t,a),ellipsisCallback:o=>this._createContextMenu(t,a,o)}));return i.length?[{type:"divider"},{label:n,type:"header"},...i].map(a=>R_(a)):ue}_getBookmarks(){const t=(n,r)=>n?aq(this._makeBookmarkMenuItems(n,r),$`Loading...`):ue;return[t(this.app.globalBookmarkDatabase,"Bookmarks on the server"),t(this.app.localBookmarkDatabase,"Bookmarks in the web browser")]}render(){const t=this.app.localBookmarkDatabase,n=t?$` <li>
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<a @click=${()=>this._addBookmark(t)}
|
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>Add bookmark...</a
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>
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@@ -3201,7 +3204,7 @@ ${n}</textarea
|
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</button>
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`}}customElements.define("genome-spy-bookmark-button",
|
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`}}customElements.define("genome-spy-bookmark-button",bq);class yq extends br{constructor(){super(),this.app=void 0,this.appInitialized=!1}static get properties(){return{app:{type:Object},appInitialized:{type:Boolean}}}createRenderRoot(){return this}_getToolButtons(){const t=this.app.provenance,n=[];t.isEnabled()&&n.push($`
|
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<genome-spy-provenance-buttons
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.provenance=${t}
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></genome-spy-provenance-buttons>
|
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@@ -3232,7 +3235,7 @@ ${n}</textarea
|
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title="Fullscreen"
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@click=${()=>this.app.toggleFullScreen()}
|
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>
|
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${Ue(
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${Ue(g$).node[0]}
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</button>
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`:ue}
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@@ -3241,7 +3244,7 @@ ${n}</textarea
|
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title="Help"
|
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@click=${()=>window.open("https://genomespy.app/docs/sample-collections/analyzing/","_blank")}
|
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>
|
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${Ue(
|
|
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${Ue(v$).node[0]}
|
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</button>
|
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`),n}render(){const t=this.app.genomeSpy;return $`
|
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<nav class="gs-toolbar">
|
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@@ -3256,25 +3259,25 @@ ${n}</textarea
|
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`:ue}
|
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${this._getToolButtons()}
|
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</nav>
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`}}customElements.define("genome-spy-toolbar",
|
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`}}customElements.define("genome-spy-toolbar",yq);class vq{constructor(t){this.storeHelper=t,this._reducers={},this.actionInfoSources=[],this._reducer=void 0,t.addReducer("provenance",(n,r)=>this._reducer?this._reducer(n,r):n??{})}addReducer(t,n){this._reducers[t]=n;const r=a=>Object.keys(this._reducers).some(o=>Me(o)&&a.type.startsWith(o)),i=(a,o)=>r(o)?o:a??null;this._reducer=tj(V1({...this._reducers,lastAction:i}),{ignoreInitialState:!0,filter:r}),this.storeHelper.dispatch({type:"@@redux/REPLACE"+Math.random().toString(36).substring(7).split("").join(".")})}get _storeState(){return this.storeHelper.store.getState()}get _provenanceState(){return this._storeState.provenance}isEnabled(){return!!this.getPresentState()}getPresentState(){return this._provenanceState.present}addActionInfoSource(t){this.actionInfoSources.push(t)}getActionInfo(t){for(const n of this.actionInfoSources){const r=n(t);if(r)return r}}dispatchBookmark(t){this.storeHelper.dispatch([...this.isUndoable()?[lo.jumpToPast(0)]:[],...t])}isRedoable(){return this.isEnabled()&&this._provenanceState.future.length>0}redo(){this.storeHelper.dispatch(lo.redo())}isUndoable(){return this.isEnabled()&&this._provenanceState.past.length>0}undo(){this.storeHelper.dispatch(lo.undo())}isAtInitialState(){return!this.isUndoable()}isEmpty(){const t=this._provenanceState;return!this.isEnabled()||t.past.length+t.future.length<=0}activateState(t){const n=this.getCurrentIndex();t<n?this.storeHelper.dispatch(lo.jumpToPast(t)):t>n&&this.storeHelper.dispatch(lo.jumpToFuture(t-n-1))}getCurrentIndex(){var t;return(t=this._provenanceState.past)==null?void 0:t.length}getActionHistory(){const t=this._provenanceState;return t.present&&[...t.past,t.present].map(n=>n.lastAction)}getFullActionHistory(){const t=this._provenanceState;return[...t.past,t.present,...t.future].map(n=>n.lastAction)}getBookmarkableActionHistory(){var t;return(t=this.getActionHistory())==null?void 0:t.slice(1)}}function wq(e,t,n=r=>+r){const r=e.length,i=new Ll,a=new Array(r).fill(0);for(const[s,c]of e.entries())c.length&&i.push(s,n(c[0]));let o=0;for(;(o=i.pop())!==void 0;){const s=e[o];let c=a[o];const l=s[c++];if(t(l),c<s.length){const u=n(s[c]);i.push(o,u),a[o]=c}}}const xq="sampleCount";class Aq extends at{constructor(n,r){super();Z(this,Cf);Z(this,_f,!0);this.view=r;const i=r.context.animator;if(this.provenance=Eq(r),!this.provenance)throw new Error("No SampleView was found!");this.provenance.storeHelper.subscribe(a=>{F(this,Cf,sv)&&(F(this,_f)&&(le(this,_f,!1),this.reset(),this.complete()),i.requestTransition(()=>{this.reset(),this._mergeAndPropagate(ab(a)),this.complete()}))}),this.contextObject=void 0}initialize(){this.contextObject=Object.create(super.getGlobalObject());const n=this.view.getEncoding().x;if(Ur(n))this.xAccessor=Oe(n.field);else throw new Error("Sample summarization requires a FieldDef. This is not a FieldDef: "+JSON.stringify(n))}handle(n){}getGlobalObject(){return this.contextObject}_getCollector(){if(this.parent instanceof Ol)return this.parent;throw new Error("MergeFacetsTransform must be a direct child of a Collector")}complete(){F(this,Cf,sv)&&this._mergeAndPropagate(this.provenance.getPresentState()[Cs]),super.complete()}_mergeAndPropagate(n){const r=[...sb(n.rootGroup)].filter(i=>t_(xn(i)));for(const[i,a]of r.entries()){const o=xn(a);if(t_(o)){this.contextObject[xq]=o.samples.length,this.beginBatch({type:"facet",facetId:[i]});const s=o.samples,c=this._getCollector();wq(s.map(l=>c.facetBatches.get([l])??[]),l=>this._propagate(l),this.xAccessor)}}this._updateScales()}setParent(n){super.setParent(n)}_updateScales(){const n=new Set;this.view.visit(r=>{if(r instanceof mt&&r.mark.encoding.y){const i=r.getScaleResolution("y");i&&n.add(i)}});for(const r of n)r.reconfigure()}}_f=new WeakMap,Cf=new WeakSet,sv=function(){return this.view.isConfiguredVisible()};function Eq(e){for(const t of e.getLayoutAncestors())if(t instanceof xb)return t.provenance}var Sq="BATCHING_REDUCER.BATCH";function _q(e){var t=arguments.length>1&&arguments[1]!==void 0?arguments[1]:Sq;return{type:t,meta:{batch:!0},payload:e}}function Cq(e){return function t(n,r){return r&&r.meta&&r.meta.batch?r.payload.reduce(t,n):e(n,r)}}class kq{constructor(t){this._reducers=t??{},this.store=hV({reducer:{}}),this._listeners=new Set,this.store.subscribe(()=>{const n=this.store.getState();for(const r of this._listeners)r(n)})}get state(){return this.store.getState()}addReducer(t,n){this._reducers[t]=n,this.store.replaceReducer(Cq(V1(this._reducers)))}subscribe(t){this._listeners.add(t)}unsubscribe(t){this._listeners.delete(t)}dispatch(t){Array.isArray(t)?this.store.dispatch(_q(t)):this.store.dispatch(t)}getDispatcher(){return t=>this.dispatch(t)}}class Tq extends G_{constructor(t){super(),this.bookmarks=t,this.names=t.map(n=>n.name)}async getNames(){return this.names}async get(t){return this.bookmarks.find(n=>n.name==t)}}xE.mergeFacets=Aq;class u6{constructor(t,n,r={}){const i=this;this.config=n,this.storeHelper=new kq,this.storeHelper.addReducer("viewSettings",Ts.reducer),this.provenance=new vq(this.storeHelper),this._initializationListeners=[],this.toolbarRef=q_(),this.appContainer=t,this._configureContainer(),this.localBookmarkDatabase=typeof n.specId=="string"?new Vj(n.specId):void 0,this.globalBookmarkDatabase=void 0,Vt($`<div class="genome-spy-app">
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<genome-spy-toolbar
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${W_(i.toolbarRef)}
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.app=${i}
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></genome-spy-toolbar>
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</div>`,i.appContainer),i.appContainer.querySelector(".genome-spy-app").addEventListener("query-dependency",s=>{s.detail.name=="app"&&(s.detail.setter(i),s.stopPropagation())});const a=s=>this.appContainer.getElementsByClassName(s)[0];this.genomeSpy=new KE(a("genome-spy-container"),this.config,r),this.genomeSpy.viewFactory.addViewType(XE,(s,c,l,u,f)=>new xb(s,c,l,u,f,this.provenance));const o=this.genomeSpy.viewVisibilityPredicate;this.genomeSpy.viewVisibilityPredicate=s=>{var c;return((c=this.storeHelper.state.viewSettings)==null?void 0:c.visibilities[s.name])??o(s)}}addInitializationListener(t){this._initializationListeners?this._initializationListeners.push(t):t()}toggleFullScreen(){document.fullscreenElement?document.exitFullscreen&&document.exitFullscreen():this.appContainer.requestFullscreen()}isFullPage(){return this.appContainer==document.body}async launch(){var o;const t=(o=this.config.bookmarks)!=null&&o.remote?Zc({baseURL:this.config.baseUrl}).load(this.config.bookmarks.remote.url).then(s=>Promise.resolve(JSON.parse(s))):Promise.resolve([]);if(!await this.genomeSpy.launch())return;this.appContainer.querySelector("canvas").setAttribute("tabindex","-1"),this.storeHelper.subscribe(Wd(s=>{var c;return(c=s.viewSettings)==null?void 0:c.visibilities},(s,c)=>{this.genomeSpy.viewRoot._invalidateCacheByPrefix("size","progeny");const l=this.genomeSpy.viewRoot.context;l.requestLayoutReflow(),l.animator.requestRender()},this.storeHelper.store.getState()));try{const s=await t;s.length&&(this.globalBookmarkDatabase=new
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<p>${a}</p>`)}return!1}_configureContainer(){this.isFullPage()?(this.appContainer.style.margin="0",this.appContainer.style.padding="0",this.appContainer.style.overflow="hidden",
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</div>`,i.appContainer),i.appContainer.querySelector(".genome-spy-app").addEventListener("query-dependency",s=>{s.detail.name=="app"&&(s.detail.setter(i),s.stopPropagation())});const a=s=>this.appContainer.getElementsByClassName(s)[0];this.genomeSpy=new KE(a("genome-spy-container"),this.config,r),this.genomeSpy.viewFactory.addViewType(XE,(s,c,l,u,f)=>new xb(s,c,l,u,f,this.provenance));const o=this.genomeSpy.viewVisibilityPredicate;this.genomeSpy.viewVisibilityPredicate=s=>{var c;return((c=this.storeHelper.state.viewSettings)==null?void 0:c.visibilities[s.name])??o(s)}}addInitializationListener(t){this._initializationListeners?this._initializationListeners.push(t):t()}toggleFullScreen(){document.fullscreenElement?document.exitFullscreen&&document.exitFullscreen():this.appContainer.requestFullscreen()}isFullPage(){return this.appContainer==document.body}async launch(){var o;const t=(o=this.config.bookmarks)!=null&&o.remote?Zc({baseURL:this.config.baseUrl}).load(this.config.bookmarks.remote.url).then(s=>Promise.resolve(JSON.parse(s))):Promise.resolve([]);if(!await this.genomeSpy.launch())return;this.appContainer.querySelector("canvas").setAttribute("tabindex","-1"),this.storeHelper.subscribe(Wd(s=>{var c;return(c=s.viewSettings)==null?void 0:c.visibilities},(s,c)=>{this.genomeSpy.viewRoot._invalidateCacheByPrefix("size","progeny");const l=this.genomeSpy.viewRoot.context;l.requestLayoutReflow(),l.animator.requestRender()},this.storeHelper.store.getState()));try{const s=await t;s.length&&(this.globalBookmarkDatabase=new Tq(s))}catch(s){throw new Error(`Cannot load remote bookmarks: ${s}`)}try{await this._restoreStateFromUrlOrBookmark()}catch(s){dn(s.toString())}this.storeHelper.subscribe(()=>{this._updateStateToUrl()}),window.addEventListener("hashchange",()=>this._restoreStateFromUrl().catch(s=>dn(s.toString())),!1);const r=bs(()=>this._updateStateToUrl(),500,!1);for(const[,s]of this.genomeSpy.getNamedScaleResolutions())s.isZoomable()&&s.addEventListener("domain",r);const i=this.toolbarRef.value;i.appInitialized=!0;const a=Lt(this.genomeSpy.spec.description??[]);this.isFullPage()&&a.length>0&&(document.title="GenomeSpy - "+a);for(const s of this._initializationListeners)s();this._initializationListeners=void 0}async _restoreStateFromUrlOrBookmark(){var i;const t=(i=this.config.bookmarks)==null?void 0:i.remote,n=this.globalBookmarkDatabase;if(!await this._restoreStateFromUrl()&&t&&n){const a=t.initialBookmark??(t.tour&&(await n.getNames())[0]);if(a){const o=await n.get(a);if(!o)throw new Error(`No such bookmark: ${a}`);t.tour?await fu(o,this,{mode:"tour",database:n,afterTourBookmark:t.afterTourBookmark}):await Pb(o,this)}}}_updateStateToUrl(){const t={actions:[],scaleDomains:{}},n=this.provenance.getBookmarkableActionHistory();n!=null&&n.length&&(t.actions=n);for(const[a,o]of this.genomeSpy.getNamedScaleResolutions().entries())o.isZoomed()||(t.scaleDomains[a]=o.getComplexDomain());const r=this.storeHelper.state.viewSettings;Object.keys(r.visibilities).length&&(t.viewSettings=r);const i=t.actions.length||Object.keys(t.scaleDomains).length||t.viewSettings?s6(t):"";window.history.replaceState(void 0,document.title,window.location.pathname+window.location.search+i)}async _restoreStateFromUrl(){var r,i;const t=window.location.hash,n=(r=t.match(/^#bookmark:(.+)$/))==null?void 0:r[1];if(n){const a=(i=this.config.bookmarks)==null?void 0:i.remote,o=this.globalBookmarkDatabase;if(a&&o){const s=(await o.getNames()).find(c=>c.replaceAll(" ","-")==n);if(s){const c=await o.get(s);if(!c)throw new Error(`No such bookmark: ${s}`);return await fu(c,this,{mode:"tour",database:o}),!0}else throw new Error(`No such bookmark: ${n}`)}}if(t&&t.length>0)try{const a=dq(t);return fu(a,this,{mode:"shared"}),!0}catch(a){console.error(a),dn($`<p>Cannot restore the state:</p>
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<p>${a}</p>`)}return!1}_configureContainer(){this.isFullPage()?(this.appContainer.style.margin="0",this.appContainer.style.padding="0",this.appContainer.style.overflow="hidden",Iq(KU)):this.appContainer.style.position="relative"}getSampleView(){var n;if(!((n=this.genomeSpy)!=null&&n.viewRoot))return;let t;return this.genomeSpy.viewRoot.visit(r=>{if(r instanceof xb)return t=r,Qa}),t}}function Iq(e){const t=document.querySelector("head"),n=document.createElement("link");n.setAttribute("rel","shortcut icon"),n.setAttribute("href",e),t.appendChild(n)}async function Rq(e,t,n={}){let r;if(Me(e)){if(r=document.querySelector(e),!r)throw new Error(`No such element: ${e}`)}else if(e instanceof HTMLElement)r=e;else throw new Error(`Invalid element: ${e}`);let i;try{const a=Xt(t)?t:await f6(t);a.baseUrl??(a.baseUrl=""),a.width??(a.width="container"),a.padding??(a.padding=10);const o=new u6(r,a,n);i=o.genomeSpy,Dq(i,n),await o.launch()}catch(a){r.innerText=a.toString(),console.error(a)}return{finalize(){for(i.destroy();r.firstChild;)r.firstChild.remove()},addEventListener(a,o){const s=i._eventListeners;let c=s.get(a);c||(c=new Set,s.set(a,c)),c.add(o)},removeEventListener(a,o){var c;(c=i._eventListeners.get(a))==null||c.delete(o)},getScaleResolutionByName(a){return i.getNamedScaleResolutions().get(a)},updateNamedData:i.updateNamedData.bind(i)}}function Dq(e,t){t.namedDataProvider&&e.registerNamedDataProvider(t.namedDataProvider)}async function f6(e){let t;try{t=JSON.parse(await Zc().load(e))}catch(n){throw new Error(`Could not load or parse configuration: ${e}, reason: ${n.message}`)}if(!t.baseUrl){const n=e.match(/^[^?#]*\//);t.baseUrl=n&&n[0]||"./"}return t}var we={},Qd={};Qd.byteLength=Pq,Qd.toByteArray=Oq,Qd.fromByteArray=zq;for(var xr=[],_n=[],Bq=typeof Uint8Array<"u"?Uint8Array:Array,Ob="ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+/",Is=0,Fq=Ob.length;Is<Fq;++Is)xr[Is]=Ob[Is],_n[Ob.charCodeAt(Is)]=Is;_n["-".charCodeAt(0)]=62,_n["_".charCodeAt(0)]=63;function h6(e){var t=e.length;if(t%4>0)throw new Error("Invalid string. Length must be a multiple of 4");var n=e.indexOf("=");n===-1&&(n=t);var r=n===t?0:4-n%4;return[n,r]}function Pq(e){var t=h6(e),n=t[0],r=t[1];return(n+r)*3/4-r}function Mq(e,t,n){return(t+n)*3/4-n}function Oq(e){var t,n=h6(e),r=n[0],i=n[1],a=new Bq(Mq(e,r,i)),o=0,s=i>0?r-4:r,c;for(c=0;c<s;c+=4)t=_n[e.charCodeAt(c)]<<18|_n[e.charCodeAt(c+1)]<<12|_n[e.charCodeAt(c+2)]<<6|_n[e.charCodeAt(c+3)],a[o++]=t>>16&255,a[o++]=t>>8&255,a[o++]=t&255;return i===2&&(t=_n[e.charCodeAt(c)]<<2|_n[e.charCodeAt(c+1)]>>4,a[o++]=t&255),i===1&&(t=_n[e.charCodeAt(c)]<<10|_n[e.charCodeAt(c+1)]<<4|_n[e.charCodeAt(c+2)]>>2,a[o++]=t>>8&255,a[o++]=t&255),a}function Lq(e){return xr[e>>18&63]+xr[e>>12&63]+xr[e>>6&63]+xr[e&63]}function Nq(e,t,n){for(var r,i=[],a=t;a<n;a+=3)r=(e[a]<<16&16711680)+(e[a+1]<<8&65280)+(e[a+2]&255),i.push(Lq(r));return i.join("")}function zq(e){for(var t,n=e.length,r=n%3,i=[],a=16383,o=0,s=n-r;o<s;o+=a)i.push(Nq(e,o,o+a>s?s:o+a));return r===1?(t=e[n-1],i.push(xr[t>>2]+xr[t<<4&63]+"==")):r===2&&(t=(e[n-2]<<8)+e[n-1],i.push(xr[t>>10]+xr[t>>4&63]+xr[t<<2&63]+"=")),i.join("")}var Lb={};/*! ieee754. BSD-3-Clause License. Feross Aboukhadijeh <https://feross.org/opensource> */Lb.read=function(e,t,n,r,i){var a,o,s=i*8-r-1,c=(1<<s)-1,l=c>>1,u=-7,f=n?i-1:0,h=n?-1:1,d=e[t+f];for(f+=h,a=d&(1<<-u)-1,d>>=-u,u+=s;u>0;a=a*256+e[t+f],f+=h,u-=8);for(o=a&(1<<-u)-1,a>>=-u,u+=r;u>0;o=o*256+e[t+f],f+=h,u-=8);if(a===0)a=1-l;else{if(a===c)return o?NaN:(d?-1:1)*(1/0);o=o+Math.pow(2,r),a=a-l}return(d?-1:1)*o*Math.pow(2,a-r)},Lb.write=function(e,t,n,r,i,a){var o,s,c,l=a*8-i-1,u=(1<<l)-1,f=u>>1,h=i===23?Math.pow(2,-24)-Math.pow(2,-77):0,d=r?0:a-1,p=r?1:-1,g=t<0||t===0&&1/t<0?1:0;for(t=Math.abs(t),isNaN(t)||t===1/0?(s=isNaN(t)?1:0,o=u):(o=Math.floor(Math.log(t)/Math.LN2),t*(c=Math.pow(2,-o))<1&&(o--,c*=2),o+f>=1?t+=h/c:t+=h*Math.pow(2,1-f),t*c>=2&&(o++,c/=2),o+f>=u?(s=0,o=u):o+f>=1?(s=(t*c-1)*Math.pow(2,i),o=o+f):(s=t*Math.pow(2,f-1)*Math.pow(2,i),o=0));i>=8;e[n+d]=s&255,d+=p,s/=256,i-=8);for(o=o<<i|s,l+=i;l>0;e[n+d]=o&255,d+=p,o/=256,l-=8);e[n+d-p]|=g*128};/*!
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* The buffer module from node.js, for the browser.
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*/(function(e){const t=Qd,n=Lb,r=typeof Symbol=="function"&&typeof Symbol.for=="function"?Symbol.for("nodejs.util.inspect.custom"):null;e.Buffer=s,e.SlowBuffer=w,e.INSPECT_MAX_BYTES=50;const i=2147483647;e.kMaxLength=i,s.TYPED_ARRAY_SUPPORT=a(),!s.TYPED_ARRAY_SUPPORT&&typeof console<"u"&&typeof console.error=="function"&&console.error("This browser lacks typed array (Uint8Array) support which is required by `buffer` v5.x. 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n=t.dyn_tree,r=t.max_code,i=t.stat_desc.static_tree,a=t.stat_desc.has_stree,o=t.stat_desc.extra_bits,s=t.stat_desc.extra_base,c=t.stat_desc.max_length,l,u,f,h,d,p,g=0;for(h=0;h<=go;h++)e.bl_count[h]=0;for(n[e.heap[e.heap_max]*2+1]=0,l=e.heap_max+1;l<v6;l++)u=e.heap[l],h=n[n[u*2+1]*2+1]+1,h>c&&(h=c,g++),n[u*2+1]=h,!(u>r)&&(e.bl_count[h]++,d=0,u>=s&&(d=o[u-s]),p=n[u*2],e.opt_len+=p*(h+d),a&&(e.static_len+=p*(i[u*2+1]+d)));if(g!==0){do{for(h=c-1;e.bl_count[h]===0;)h--;e.bl_count[h]--,e.bl_count[h+1]+=2,e.bl_count[c]--,g-=2}while(g>0);for(h=c;h!==0;h--)for(u=e.bl_count[h];u!==0;)f=e.heap[--l],!(f>r)&&(n[f*2+1]!==h&&(e.opt_len+=(h-n[f*2+1])*n[f*2],n[f*2+1]=h),u--)}}function I6(e,t,n){var r=new Array(go+1),i=0,a,o;for(a=1;a<=go;a++)r[a]=i=i+n[a-1]<<1;for(o=0;o<=t;o++){var s=e[o*2+1];s!==0&&(e[o*2]=T6(r[s]++,s))}}function tW(){var e,t,n,r,i,a=new Array(go+1);for(n=0,r=0;r<zb-1;r++)for(Vb[r]=n,e=0;e<1<<Gb[r];e++)yu[n++]=r;for(yu[n-1]=r,i=0,r=0;r<16;r++)for(Kd[r]=i,e=0;e<1<<Xd[r];e++)bu[i++]=r;for(i>>=7;r<Bs;r++)for(Kd[r]=i<<7,e=0;e<1<<Xd[r]-7;e++)bu[256+i++]=r;for(t=0;t<=go;t++)a[t]=0;for(e=0;e<=143;)Jr[e*2+1]=8,e++,a[8]++;for(;e<=255;)Jr[e*2+1]=9,e++,a[9]++;for(;e<=279;)Jr[e*2+1]=7,e++,a[7]++;for(;e<=287;)Jr[e*2+1]=8,e++,a[8]++;for(I6(Jr,gu+1,a),e=0;e<Bs;e++)mu[e*2+1]=5,mu[e*2]=T6(e,5);S6=new jb(Jr,Gb,pu+1,gu,go),_6=new jb(mu,Xd,0,Bs,go),C6=new jb(new Array(0),Xq,0,Ub,Qq)}function R6(e){var t;for(t=0;t<gu;t++)e.dyn_ltree[t*2]=0;for(t=0;t<Bs;t++)e.dyn_dtree[t*2]=0;for(t=0;t<Ub;t++)e.bl_tree[t*2]=0;e.dyn_ltree[Hb*2]=1,e.opt_len=e.static_len=0,e.last_lit=e.matches=0}function D6(e){e.bi_valid>8?vu(e,e.bi_buf):e.bi_valid>0&&(e.pending_buf[e.pending++]=e.bi_buf),e.bi_buf=0,e.bi_valid=0}function nW(e,t,n,r){D6(e),r&&(vu(e,n),vu(e,~n)),Gq.arraySet(e.pending_buf,e.window,t,n,e.pending),e.pending+=n}function B6(e,t,n,r){var i=t*2,a=n*2;return e[i]<e[a]||e[i]===e[a]&&r[t]<=r[n]}function Wb(e,t,n){for(var r=e.heap[n],i=n<<1;i<=e.heap_len&&(i<e.heap_len&&B6(t,e.heap[i+1],e.heap[i],e.depth)&&i++,!B6(t,r,e.heap[i],e.depth));)e.heap[n]=e.heap[i],n=i,i<<=1;e.heap[n]=r}function F6(e,t,n){var r,i,a=0,o,s;if(e.last_lit!==0)do r=e.pending_buf[e.d_buf+a*2]<<8|e.pending_buf[e.d_buf+a*2+1],i=e.pending_buf[e.l_buf+a],a++,r===0?Er(e,i,t):(o=yu[i],Er(e,o+pu+1,t),s=Gb[o],s!==0&&(i-=Vb[o],an(e,i,s)),r--,o=k6(r),Er(e,o,n),s=Xd[o],s!==0&&(r-=Kd[o],an(e,r,s)));while(a<e.last_lit);Er(e,Hb,t)}function Yb(e,t){var n=t.dyn_tree,r=t.stat_desc.static_tree,i=t.stat_desc.has_stree,a=t.stat_desc.elems,o,s,c=-1,l;for(e.heap_len=0,e.heap_max=v6,o=0;o<a;o++)n[o*2]!==0?(e.heap[++e.heap_len]=c=o,e.depth[o]=0):n[o*2+1]=0;for(;e.heap_len<2;)l=e.heap[++e.heap_len]=c<2?++c:0,n[l*2]=1,e.depth[l]=0,e.opt_len--,i&&(e.static_len-=r[l*2+1]);for(t.max_code=c,o=e.heap_len>>1;o>=1;o--)Wb(e,n,o);l=a;do o=e.heap[1],e.heap[1]=e.heap[e.heap_len--],Wb(e,n,1),s=e.heap[1],e.heap[--e.heap_max]=o,e.heap[--e.heap_max]=s,n[l*2]=n[o*2]+n[s*2],e.depth[l]=(e.depth[o]>=e.depth[s]?e.depth[o]:e.depth[s])+1,n[o*2+1]=n[s*2+1]=l,e.heap[1]=l++,Wb(e,n,1);while(e.heap_len>=2);e.heap[--e.heap_max]=e.heap[1],eW(e,t),I6(n,c,e.bl_count)}function P6(e,t,n){var r,i=-1,a,o=t[0*2+1],s=0,c=7,l=4;for(o===0&&(c=138,l=3),t[(n+1)*2+1]=65535,r=0;r<=n;r++)a=o,o=t[(r+1)*2+1],!(++s<c&&a===o)&&(s<l?e.bl_tree[a*2]+=s:a!==0?(a!==i&&e.bl_tree[a*2]++,e.bl_tree[w6*2]++):s<=10?e.bl_tree[x6*2]++:e.bl_tree[A6*2]++,s=0,i=a,o===0?(c=138,l=3):a===o?(c=6,l=3):(c=7,l=4))}function M6(e,t,n){var r,i=-1,a,o=t[0*2+1],s=0,c=7,l=4;for(o===0&&(c=138,l=3),r=0;r<=n;r++)if(a=o,o=t[(r+1)*2+1],!(++s<c&&a===o)){if(s<l)do Er(e,a,e.bl_tree);while(--s!==0);else a!==0?(a!==i&&(Er(e,a,e.bl_tree),s--),Er(e,w6,e.bl_tree),an(e,s-3,2)):s<=10?(Er(e,x6,e.bl_tree),an(e,s-3,3)):(Er(e,A6,e.bl_tree),an(e,s-11,7));s=0,i=a,o===0?(c=138,l=3):a===o?(c=6,l=3):(c=7,l=4)}}function rW(e){var t;for(P6(e,e.dyn_ltree,e.l_desc.max_code),P6(e,e.dyn_dtree,e.d_desc.max_code),Yb(e,e.bl_desc),t=Ub-1;t>=3&&e.bl_tree[E6[t]*2+1]===0;t--);return e.opt_len+=3*(t+1)+5+5+4,t}function iW(e,t,n,r){var i;for(an(e,t-257,5),an(e,n-1,5),an(e,r-4,4),i=0;i<r;i++)an(e,e.bl_tree[E6[i]*2+1],3);M6(e,e.dyn_ltree,t-1),M6(e,e.dyn_dtree,n-1)}function aW(e){var t=4093624447,n;for(n=0;n<=31;n++,t>>>=1)if(t&1&&e.dyn_ltree[n*2]!==0)return m6;if(e.dyn_ltree[9*2]!==0||e.dyn_ltree[10*2]!==0||e.dyn_ltree[13*2]!==0)return b6;for(n=32;n<pu;n++)if(e.dyn_ltree[n*2]!==0)return b6;return m6}var O6=!1;function oW(e){O6||(tW(),O6=!0),e.l_desc=new qb(e.dyn_ltree,S6),e.d_desc=new qb(e.dyn_dtree,_6),e.bl_desc=new qb(e.bl_tree,C6),e.bi_buf=0,e.bi_valid=0,R6(e)}function L6(e,t,n,r){an(e,(qq<<1)+(r?1:0),3),nW(e,t,n,!0)}function sW(e){an(e,y6<<1,3),Er(e,Hb,Jr),Jq(e)}function cW(e,t,n,r){var i,a,o=0;e.level>0?(e.strm.data_type===jq&&(e.strm.data_type=aW(e)),Yb(e,e.l_desc),Yb(e,e.d_desc),o=rW(e),i=e.opt_len+3+7>>>3,a=e.static_len+3+7>>>3,a<=i&&(i=a)):i=a=n+5,n+4<=i&&t!==-1?L6(e,t,n,r):e.strategy===Vq||a===i?(an(e,(y6<<1)+(r?1:0),3),F6(e,Jr,mu)):(an(e,(Wq<<1)+(r?1:0),3),iW(e,e.l_desc.max_code+1,e.d_desc.max_code+1,o+1),F6(e,e.dyn_ltree,e.dyn_dtree)),R6(e),r&&D6(e)}function lW(e,t,n){return e.pending_buf[e.d_buf+e.last_lit*2]=t>>>8&255,e.pending_buf[e.d_buf+e.last_lit*2+1]=t&255,e.pending_buf[e.l_buf+e.last_lit]=n&255,e.last_lit++,t===0?e.dyn_ltree[n*2]++:(e.matches++,t--,e.dyn_ltree[(yu[n]+pu+1)*2]++,e.dyn_dtree[k6(t)*2]++),e.last_lit===e.lit_bufsize-1}Rs._tr_init=oW,Rs._tr_stored_block=L6,Rs._tr_flush_block=cW,Rs._tr_tally=lW,Rs._tr_align=sW;function uW(e,t,n,r){for(var i=e&65535|0,a=e>>>16&65535|0,o=0;n!==0;){o=n>2e3?2e3:n,n-=o;do i=i+t[r++]|0,a=a+i|0;while(--o);i%=65521,a%=65521}return i|a<<16|0}var N6=uW;function fW(){for(var e,t=[],n=0;n<256;n++){e=n;for(var r=0;r<8;r++)e=e&1?3988292384^e>>>1:e>>>1;t[n]=e}return t}var hW=fW();function dW(e,t,n,r){var i=hW,a=r+n;e^=-1;for(var o=r;o<a;o++)e=e>>>8^i[(e^t[o])&255];return e^-1}var z6=dW,Zb={2:"need dictionary",1:"stream end",0:"","-1":"file error","-2":"stream error","-3":"data error","-4":"insufficient memory","-5":"buffer error","-6":"incompatible version"},Wt=Kr,Cn=Rs,U6=N6,Wi=z6,pW=Zb,mo=0,gW=1,mW=3,Yi=4,$6=5,Sr=0,H6=1,kn=-2,bW=-3,Qb=-5,yW=-1,vW=1,Jd=2,wW=3,xW=4,AW=0,EW=2,e0=8,SW=9,_W=15,CW=8,kW=29,TW=256,Xb=TW+1+kW,IW=30,RW=19,DW=2*Xb+1,BW=15,be=3,Zi=258,er=Zi+be+1,FW=32,t0=42,Kb=69,n0=73,r0=91,i0=103,bo=113,wu=666,yt=1,xu=2,yo=3,Fs=4,PW=3;function Qi(e,t){return e.msg=pW[t],t}function G6(e){return(e<<1)-(e>4?9:0)}function Xi(e){for(var t=e.length;--t>=0;)e[t]=0}function Ki(e){var t=e.state,n=t.pending;n>e.avail_out&&(n=e.avail_out),n!==0&&(Wt.arraySet(e.output,t.pending_buf,t.pending_out,n,e.next_out),e.next_out+=n,t.pending_out+=n,e.total_out+=n,e.avail_out-=n,t.pending-=n,t.pending===0&&(t.pending_out=0))}function Pt(e,t){Cn._tr_flush_block(e,e.block_start>=0?e.block_start:-1,e.strstart-e.block_start,t),e.block_start=e.strstart,Ki(e.strm)}function Se(e,t){e.pending_buf[e.pending++]=t}function Au(e,t){e.pending_buf[e.pending++]=t>>>8&255,e.pending_buf[e.pending++]=t&255}function MW(e,t,n,r){var i=e.avail_in;return i>r&&(i=r),i===0?0:(e.avail_in-=i,Wt.arraySet(t,e.input,e.next_in,i,n),e.state.wrap===1?e.adler=U6(e.adler,t,i,n):e.state.wrap===2&&(e.adler=Wi(e.adler,t,i,n)),e.next_in+=i,e.total_in+=i,i)}function V6(e,t){var n=e.max_chain_length,r=e.strstart,i,a,o=e.prev_length,s=e.nice_match,c=e.strstart>e.w_size-er?e.strstart-(e.w_size-er):0,l=e.window,u=e.w_mask,f=e.prev,h=e.strstart+Zi,d=l[r+o-1],p=l[r+o];e.prev_length>=e.good_match&&(n>>=2),s>e.lookahead&&(s=e.lookahead);do if(i=t,!(l[i+o]!==p||l[i+o-1]!==d||l[i]!==l[r]||l[++i]!==l[r+1])){r+=2,i++;do;while(l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&r<h);if(a=Zi-(h-r),r=h-Zi,a>o){if(e.match_start=t,o=a,a>=s)break;d=l[r+o-1],p=l[r+o]}}while((t=f[t&u])>c&&--n!==0);return o<=e.lookahead?o:e.lookahead}function vo(e){var t=e.w_size,n,r,i,a,o;do{if(a=e.window_size-e.lookahead-e.strstart,e.strstart>=t+(t-er)){Wt.arraySet(e.window,e.window,t,t,0),e.match_start-=t,e.strstart-=t,e.block_start-=t,r=e.hash_size,n=r;do i=e.head[--n],e.head[n]=i>=t?i-t:0;while(--r);r=t,n=r;do i=e.prev[--n],e.prev[n]=i>=t?i-t:0;while(--r);a+=t}if(e.strm.avail_in===0)break;if(r=MW(e.strm,e.window,e.strstart+e.lookahead,a),e.lookahead+=r,e.lookahead+e.insert>=be)for(o=e.strstart-e.insert,e.ins_h=e.window[o],e.ins_h=(e.ins_h<<e.hash_shift^e.window[o+1])&e.hash_mask;e.insert&&(e.ins_h=(e.ins_h<<e.hash_shift^e.window[o+be-1])&e.hash_mask,e.prev[o&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=o,o++,e.insert--,!(e.lookahead+e.insert<be)););}while(e.lookahead<er&&e.strm.avail_in!==0)}function OW(e,t){var n=65535;for(n>e.pending_buf_size-5&&(n=e.pending_buf_size-5);;){if(e.lookahead<=1){if(vo(e),e.lookahead===0&&t===mo)return yt;if(e.lookahead===0)break}e.strstart+=e.lookahead,e.lookahead=0;var r=e.block_start+n;if((e.strstart===0||e.strstart>=r)&&(e.lookahead=e.strstart-r,e.strstart=r,Pt(e,!1),e.strm.avail_out===0)||e.strstart-e.block_start>=e.w_size-er&&(Pt(e,!1),e.strm.avail_out===0))return yt}return e.insert=0,t===Yi?(Pt(e,!0),e.strm.avail_out===0?yo:Fs):(e.strstart>e.block_start&&(Pt(e,!1),e.strm.avail_out===0),yt)}function Jb(e,t){for(var n,r;;){if(e.lookahead<er){if(vo(e),e.lookahead<er&&t===mo)return yt;if(e.lookahead===0)break}if(n=0,e.lookahead>=be&&(e.ins_h=(e.ins_h<<e.hash_shift^e.window[e.strstart+be-1])&e.hash_mask,n=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart),n!==0&&e.strstart-n<=e.w_size-er&&(e.match_length=V6(e,n)),e.match_length>=be)if(r=Cn._tr_tally(e,e.strstart-e.match_start,e.match_length-be),e.lookahead-=e.match_length,e.match_length<=e.max_lazy_match&&e.lookahead>=be){e.match_length--;do e.strstart++,e.ins_h=(e.ins_h<<e.hash_shift^e.window[e.strstart+be-1])&e.hash_mask,n=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart;while(--e.match_length!==0);e.strstart++}else e.strstart+=e.match_length,e.match_length=0,e.ins_h=e.window[e.strstart],e.ins_h=(e.ins_h<<e.hash_shift^e.window[e.strstart+1])&e.hash_mask;else r=Cn._tr_tally(e,0,e.window[e.strstart]),e.lookahead--,e.strstart++;if(r&&(Pt(e,!1),e.strm.avail_out===0))return yt}return e.insert=e.strstart<be-1?e.strstart:be-1,t===Yi?(Pt(e,!0),e.strm.avail_out===0?yo:Fs):e.last_lit&&(Pt(e,!1),e.strm.avail_out===0)?yt:xu}function Ps(e,t){for(var n,r,i;;){if(e.lookahead<er){if(vo(e),e.lookahead<er&&t===mo)return yt;if(e.lookahead===0)break}if(n=0,e.lookahead>=be&&(e.ins_h=(e.ins_h<<e.hash_shift^e.window[e.strstart+be-1])&e.hash_mask,n=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart),e.prev_length=e.match_length,e.prev_match=e.match_start,e.match_length=be-1,n!==0&&e.prev_length<e.max_lazy_match&&e.strstart-n<=e.w_size-er&&(e.match_length=V6(e,n),e.match_length<=5&&(e.strategy===vW||e.match_length===be&&e.strstart-e.match_start>4096)&&(e.match_length=be-1)),e.prev_length>=be&&e.match_length<=e.prev_length){i=e.strstart+e.lookahead-be,r=Cn._tr_tally(e,e.strstart-1-e.prev_match,e.prev_length-be),e.lookahead-=e.prev_length-1,e.prev_length-=2;do++e.strstart<=i&&(e.ins_h=(e.ins_h<<e.hash_shift^e.window[e.strstart+be-1])&e.hash_mask,n=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart);while(--e.prev_length!==0);if(e.match_available=0,e.match_length=be-1,e.strstart++,r&&(Pt(e,!1),e.strm.avail_out===0))return yt}else if(e.match_available){if(r=Cn._tr_tally(e,0,e.window[e.strstart-1]),r&&Pt(e,!1),e.strstart++,e.lookahead--,e.strm.avail_out===0)return yt}else e.match_available=1,e.strstart++,e.lookahead--}return e.match_available&&(r=Cn._tr_tally(e,0,e.window[e.strstart-1]),e.match_available=0),e.insert=e.strstart<be-1?e.strstart:be-1,t===Yi?(Pt(e,!0),e.strm.avail_out===0?yo:Fs):e.last_lit&&(Pt(e,!1),e.strm.avail_out===0)?yt:xu}function LW(e,t){for(var n,r,i,a,o=e.window;;){if(e.lookahead<=Zi){if(vo(e),e.lookahead<=Zi&&t===mo)return yt;if(e.lookahead===0)break}if(e.match_length=0,e.lookahead>=be&&e.strstart>0&&(i=e.strstart-1,r=o[i],r===o[++i]&&r===o[++i]&&r===o[++i])){a=e.strstart+Zi;do;while(r===o[++i]&&r===o[++i]&&r===o[++i]&&r===o[++i]&&r===o[++i]&&r===o[++i]&&r===o[++i]&&r===o[++i]&&i<a);e.match_length=Zi-(a-i),e.match_length>e.lookahead&&(e.match_length=e.lookahead)}if(e.match_length>=be?(n=Cn._tr_tally(e,1,e.match_length-be),e.lookahead-=e.match_length,e.strstart+=e.match_length,e.match_length=0):(n=Cn._tr_tally(e,0,e.window[e.strstart]),e.lookahead--,e.strstart++),n&&(Pt(e,!1),e.strm.avail_out===0))return yt}return e.insert=0,t===Yi?(Pt(e,!0),e.strm.avail_out===0?yo:Fs):e.last_lit&&(Pt(e,!1),e.strm.avail_out===0)?yt:xu}function NW(e,t){for(var n;;){if(e.lookahead===0&&(vo(e),e.lookahead===0)){if(t===mo)return yt;break}if(e.match_length=0,n=Cn._tr_tally(e,0,e.window[e.strstart]),e.lookahead--,e.strstart++,n&&(Pt(e,!1),e.strm.avail_out===0))return yt}return e.insert=0,t===Yi?(Pt(e,!0),e.strm.avail_out===0?yo:Fs):e.last_lit&&(Pt(e,!1),e.strm.avail_out===0)?yt:xu}function _r(e,t,n,r,i){this.good_length=e,this.max_lazy=t,this.nice_length=n,this.max_chain=r,this.func=i}var Ms;Ms=[new _r(0,0,0,0,OW),new _r(4,4,8,4,Jb),new _r(4,5,16,8,Jb),new _r(4,6,32,32,Jb),new _r(4,4,16,16,Ps),new _r(8,16,32,32,Ps),new _r(8,16,128,128,Ps),new _r(8,32,128,256,Ps),new _r(32,128,258,1024,Ps),new _r(32,258,258,4096,Ps)];function zW(e){e.window_size=2*e.w_size,Xi(e.head),e.max_lazy_match=Ms[e.level].max_lazy,e.good_match=Ms[e.level].good_length,e.nice_match=Ms[e.level].nice_length,e.max_chain_length=Ms[e.level].max_chain,e.strstart=0,e.block_start=0,e.lookahead=0,e.insert=0,e.match_length=e.prev_length=be-1,e.match_available=0,e.ins_h=0}function UW(){this.strm=null,this.status=0,this.pending_buf=null,this.pending_buf_size=0,this.pending_out=0,this.pending=0,this.wrap=0,this.gzhead=null,this.gzindex=0,this.method=e0,this.last_flush=-1,this.w_size=0,this.w_bits=0,this.w_mask=0,this.window=null,this.window_size=0,this.prev=null,this.head=null,this.ins_h=0,this.hash_size=0,this.hash_bits=0,this.hash_mask=0,this.hash_shift=0,this.block_start=0,this.match_length=0,this.prev_match=0,this.match_available=0,this.strstart=0,this.match_start=0,this.lookahead=0,this.prev_length=0,this.max_chain_length=0,this.max_lazy_match=0,this.level=0,this.strategy=0,this.good_match=0,this.nice_match=0,this.dyn_ltree=new Wt.Buf16(DW*2),this.dyn_dtree=new Wt.Buf16((2*IW+1)*2),this.bl_tree=new Wt.Buf16((2*RW+1)*2),Xi(this.dyn_ltree),Xi(this.dyn_dtree),Xi(this.bl_tree),this.l_desc=null,this.d_desc=null,this.bl_desc=null,this.bl_count=new Wt.Buf16(BW+1),this.heap=new Wt.Buf16(2*Xb+1),Xi(this.heap),this.heap_len=0,this.heap_max=0,this.depth=new Wt.Buf16(2*Xb+1),Xi(this.depth),this.l_buf=0,this.lit_bufsize=0,this.last_lit=0,this.d_buf=0,this.opt_len=0,this.static_len=0,this.matches=0,this.insert=0,this.bi_buf=0,this.bi_valid=0}function j6(e){var t;return!e||!e.state?Qi(e,kn):(e.total_in=e.total_out=0,e.data_type=EW,t=e.state,t.pending=0,t.pending_out=0,t.wrap<0&&(t.wrap=-t.wrap),t.status=t.wrap?t0:bo,e.adler=t.wrap===2?0:1,t.last_flush=mo,Cn._tr_init(t),Sr)}function q6(e){var t=j6(e);return t===Sr&&zW(e.state),t}function $W(e,t){return!e||!e.state||e.state.wrap!==2?kn:(e.state.gzhead=t,Sr)}function W6(e,t,n,r,i,a){if(!e)return kn;var o=1;if(t===yW&&(t=6),r<0?(o=0,r=-r):r>15&&(o=2,r-=16),i<1||i>SW||n!==e0||r<8||r>15||t<0||t>9||a<0||a>xW)return Qi(e,kn);r===8&&(r=9);var s=new UW;return e.state=s,s.strm=e,s.wrap=o,s.gzhead=null,s.w_bits=r,s.w_size=1<<s.w_bits,s.w_mask=s.w_size-1,s.hash_bits=i+7,s.hash_size=1<<s.hash_bits,s.hash_mask=s.hash_size-1,s.hash_shift=~~((s.hash_bits+be-1)/be),s.window=new Wt.Buf8(s.w_size*2),s.head=new Wt.Buf16(s.hash_size),s.prev=new Wt.Buf16(s.w_size),s.lit_bufsize=1<<i+6,s.pending_buf_size=s.lit_bufsize*4,s.pending_buf=new Wt.Buf8(s.pending_buf_size),s.d_buf=1*s.lit_bufsize,s.l_buf=(1+2)*s.lit_bufsize,s.level=t,s.strategy=a,s.method=n,q6(e)}function HW(e,t){return W6(e,t,e0,_W,CW,AW)}function GW(e,t){var n,r,i,a;if(!e||!e.state||t>$6||t<0)return e?Qi(e,kn):kn;if(r=e.state,!e.output||!e.input&&e.avail_in!==0||r.status===wu&&t!==Yi)return Qi(e,e.avail_out===0?Qb:kn);if(r.strm=e,n=r.last_flush,r.last_flush=t,r.status===t0)if(r.wrap===2)e.adler=0,Se(r,31),Se(r,139),Se(r,8),r.gzhead?(Se(r,(r.gzhead.text?1:0)+(r.gzhead.hcrc?2:0)+(r.gzhead.extra?4:0)+(r.gzhead.name?8:0)+(r.gzhead.comment?16:0)),Se(r,r.gzhead.time&255),Se(r,r.gzhead.time>>8&255),Se(r,r.gzhead.time>>16&255),Se(r,r.gzhead.time>>24&255),Se(r,r.level===9?2:r.strategy>=Jd||r.level<2?4:0),Se(r,r.gzhead.os&255),r.gzhead.extra&&r.gzhead.extra.length&&(Se(r,r.gzhead.extra.length&255),Se(r,r.gzhead.extra.length>>8&255)),r.gzhead.hcrc&&(e.adler=Wi(e.adler,r.pending_buf,r.pending,0)),r.gzindex=0,r.status=Kb):(Se(r,0),Se(r,0),Se(r,0),Se(r,0),Se(r,0),Se(r,r.level===9?2:r.strategy>=Jd||r.level<2?4:0),Se(r,PW),r.status=bo);else{var o=e0+(r.w_bits-8<<4)<<8,s=-1;r.strategy>=Jd||r.level<2?s=0:r.level<6?s=1:r.level===6?s=2:s=3,o|=s<<6,r.strstart!==0&&(o|=FW),o+=31-o%31,r.status=bo,Au(r,o),r.strstart!==0&&(Au(r,e.adler>>>16),Au(r,e.adler&65535)),e.adler=1}if(r.status===Kb)if(r.gzhead.extra){for(i=r.pending;r.gzindex<(r.gzhead.extra.length&65535)&&!(r.pending===r.pending_buf_size&&(r.gzhead.hcrc&&r.pending>i&&(e.adler=Wi(e.adler,r.pending_buf,r.pending-i,i)),Ki(e),i=r.pending,r.pending===r.pending_buf_size));)Se(r,r.gzhead.extra[r.gzindex]&255),r.gzindex++;r.gzhead.hcrc&&r.pending>i&&(e.adler=Wi(e.adler,r.pending_buf,r.pending-i,i)),r.gzindex===r.gzhead.extra.length&&(r.gzindex=0,r.status=n0)}else r.status=n0;if(r.status===n0)if(r.gzhead.name){i=r.pending;do{if(r.pending===r.pending_buf_size&&(r.gzhead.hcrc&&r.pending>i&&(e.adler=Wi(e.adler,r.pending_buf,r.pending-i,i)),Ki(e),i=r.pending,r.pending===r.pending_buf_size)){a=1;break}r.gzindex<r.gzhead.name.length?a=r.gzhead.name.charCodeAt(r.gzindex++)&255:a=0,Se(r,a)}while(a!==0);r.gzhead.hcrc&&r.pending>i&&(e.adler=Wi(e.adler,r.pending_buf,r.pending-i,i)),a===0&&(r.gzindex=0,r.status=r0)}else r.status=r0;if(r.status===r0)if(r.gzhead.comment){i=r.pending;do{if(r.pending===r.pending_buf_size&&(r.gzhead.hcrc&&r.pending>i&&(e.adler=Wi(e.adler,r.pending_buf,r.pending-i,i)),Ki(e),i=r.pending,r.pending===r.pending_buf_size)){a=1;break}r.gzindex<r.gzhead.comment.length?a=r.gzhead.comment.charCodeAt(r.gzindex++)&255:a=0,Se(r,a)}while(a!==0);r.gzhead.hcrc&&r.pending>i&&(e.adler=Wi(e.adler,r.pending_buf,r.pending-i,i)),a===0&&(r.status=i0)}else r.status=i0;if(r.status===i0&&(r.gzhead.hcrc?(r.pending+2>r.pending_buf_size&&Ki(e),r.pending+2<=r.pending_buf_size&&(Se(r,e.adler&255),Se(r,e.adler>>8&255),e.adler=0,r.status=bo)):r.status=bo),r.pending!==0){if(Ki(e),e.avail_out===0)return r.last_flush=-1,Sr}else if(e.avail_in===0&&G6(t)<=G6(n)&&t!==Yi)return Qi(e,Qb);if(r.status===wu&&e.avail_in!==0)return Qi(e,Qb);if(e.avail_in!==0||r.lookahead!==0||t!==mo&&r.status!==wu){var c=r.strategy===Jd?NW(r,t):r.strategy===wW?LW(r,t):Ms[r.level].func(r,t);if((c===yo||c===Fs)&&(r.status=wu),c===yt||c===yo)return e.avail_out===0&&(r.last_flush=-1),Sr;if(c===xu&&(t===gW?Cn._tr_align(r):t!==$6&&(Cn._tr_stored_block(r,0,0,!1),t===mW&&(Xi(r.head),r.lookahead===0&&(r.strstart=0,r.block_start=0,r.insert=0))),Ki(e),e.avail_out===0))return r.last_flush=-1,Sr}return t!==Yi?Sr:r.wrap<=0?H6:(r.wrap===2?(Se(r,e.adler&255),Se(r,e.adler>>8&255),Se(r,e.adler>>16&255),Se(r,e.adler>>24&255),Se(r,e.total_in&255),Se(r,e.total_in>>8&255),Se(r,e.total_in>>16&255),Se(r,e.total_in>>24&255)):(Au(r,e.adler>>>16),Au(r,e.adler&65535)),Ki(e),r.wrap>0&&(r.wrap=-r.wrap),r.pending!==0?Sr:H6)}function VW(e){var t;return!e||!e.state?kn:(t=e.state.status,t!==t0&&t!==Kb&&t!==n0&&t!==r0&&t!==i0&&t!==bo&&t!==wu?Qi(e,kn):(e.state=null,t===bo?Qi(e,bW):Sr))}function jW(e,t){var n=t.length,r,i,a,o,s,c,l,u;if(!e||!e.state||(r=e.state,o=r.wrap,o===2||o===1&&r.status!==t0||r.lookahead))return kn;for(o===1&&(e.adler=U6(e.adler,t,n,0)),r.wrap=0,n>=r.w_size&&(o===0&&(Xi(r.head),r.strstart=0,r.block_start=0,r.insert=0),u=new Wt.Buf8(r.w_size),Wt.arraySet(u,t,n-r.w_size,r.w_size,0),t=u,n=r.w_size),s=e.avail_in,c=e.next_in,l=e.input,e.avail_in=n,e.next_in=0,e.input=t,vo(r);r.lookahead>=be;){i=r.strstart,a=r.lookahead-(be-1);do 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t,n,r,i,a,o=e.length,s=0;for(i=0;i<o;i++)n=e.charCodeAt(i),(n&64512)===55296&&i+1<o&&(r=e.charCodeAt(i+1),(r&64512)===56320&&(n=65536+(n-55296<<10)+(r-56320),i++)),s+=n<128?1:n<2048?2:n<65536?3:4;for(t=new a0.Buf8(s),a=0,i=0;a<s;i++)n=e.charCodeAt(i),(n&64512)===55296&&i+1<o&&(r=e.charCodeAt(i+1),(r&64512)===56320&&(n=65536+(n-55296<<10)+(r-56320),i++)),n<128?t[a++]=n:n<2048?(t[a++]=192|n>>>6,t[a++]=128|n&63):n<65536?(t[a++]=224|n>>>12,t[a++]=128|n>>>6&63,t[a++]=128|n&63):(t[a++]=240|n>>>18,t[a++]=128|n>>>12&63,t[a++]=128|n>>>6&63,t[a++]=128|n&63);return t};function Q6(e,t){if(t<65534&&(e.subarray&&Z6||!e.subarray&&Y6))return String.fromCharCode.apply(null,a0.shrinkBuf(e,t));for(var n="",r=0;r<t;r++)n+=String.fromCharCode(e[r]);return n}wo.buf2binstring=function(e){return Q6(e,e.length)},wo.binstring2buf=function(e){for(var t=new a0.Buf8(e.length),n=0,r=t.length;n<r;n++)t[n]=e.charCodeAt(n);return t},wo.buf2string=function(e,t){var n,r,i,a,o=t||e.length,s=new 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t=this.options;t.raw&&t.windowBits>0?t.windowBits=-t.windowBits:t.gzip&&t.windowBits>0&&t.windowBits<16&&(t.windowBits+=16),this.err=0,this.msg="",this.ended=!1,this.chunks=[],this.strm=new WW,this.strm.avail_out=0;var n=Su.deflateInit2(this.strm,t.level,t.method,t.windowBits,t.memLevel,t.strategy);if(n!==Os)throw new Error(ty[n]);if(t.header&&Su.deflateSetHeader(this.strm,t.header),t.dictionary){var r;if(typeof t.dictionary=="string"?r=ey.string2buf(t.dictionary):K6.call(t.dictionary)==="[object ArrayBuffer]"?r=new Uint8Array(t.dictionary):r=t.dictionary,n=Su.deflateSetDictionary(this.strm,r),n!==Os)throw new Error(ty[n]);this._dict_set=!0}}xo.prototype.push=function(e,t){var n=this.strm,r=this.options.chunkSize,i,a;if(this.ended)return!1;a=t===~~t?t:t===!0?ny:YW,typeof e=="string"?n.input=ey.string2buf(e):K6.call(e)==="[object ArrayBuffer]"?n.input=new Uint8Array(e):n.input=e,n.next_in=0,n.avail_in=n.input.length;do{if(n.avail_out===0&&(n.output=new _u.Buf8(r),n.next_out=0,n.avail_out=r),i=Su.deflate(n,a),i!==J6&&i!==Os)return this.onEnd(i),this.ended=!0,!1;(n.avail_out===0||n.avail_in===0&&(a===ny||a===eC))&&(this.options.to==="string"?this.onData(ey.buf2binstring(_u.shrinkBuf(n.output,n.next_out))):this.onData(_u.shrinkBuf(n.output,n.next_out)))}while((n.avail_in>0||n.avail_out===0)&&i!==J6);return a===ny?(i=Su.deflateEnd(this.strm),this.onEnd(i),this.ended=!0,i===Os):(a===eC&&(this.onEnd(Os),n.avail_out=0),!0)},xo.prototype.onData=function(e){this.chunks.push(e)},xo.prototype.onEnd=function(e){e===Os&&(this.options.to==="string"?this.result=this.chunks.join(""):this.result=_u.flattenChunks(this.chunks)),this.chunks=[],this.err=e,this.msg=this.strm.msg};function ry(e,t){var n=new xo(t);if(n.push(e,!0),n.err)throw n.msg||ty[n.err];return n.result}function KW(e,t){return t=t||{},t.raw=!0,ry(e,t)}function JW(e,t){return t=t||{},t.gzip=!0,ry(e,t)}du.Deflate=xo,du.deflate=ry,du.deflateRaw=KW,du.gzip=JW;var Cu={},tr={},o0=30,eY=12,tY=function(t,n){var r,i,a,o,s,c,l,u,f,h,d,p,g,b,y,w,A,x,C,_,I,D,M,G,O;r=t.state,i=t.next_in,G=t.input,a=i+(t.avail_in-5),o=t.next_out,O=t.output,s=o-(n-t.avail_out),c=o+(t.avail_out-257),l=r.dmax,u=r.wsize,f=r.whave,h=r.wnext,d=r.window,p=r.hold,g=r.bits,b=r.lencode,y=r.distcode,w=(1<<r.lenbits)-1,A=(1<<r.distbits)-1;e:do{g<15&&(p+=G[i++]<<g,g+=8,p+=G[i++]<<g,g+=8),x=b[p&w];t:for(;;){if(C=x>>>24,p>>>=C,g-=C,C=x>>>16&255,C===0)O[o++]=x&65535;else if(C&16){_=x&65535,C&=15,C&&(g<C&&(p+=G[i++]<<g,g+=8),_+=p&(1<<C)-1,p>>>=C,g-=C),g<15&&(p+=G[i++]<<g,g+=8,p+=G[i++]<<g,g+=8),x=y[p&A];n:for(;;){if(C=x>>>24,p>>>=C,g-=C,C=x>>>16&255,C&16){if(I=x&65535,C&=15,g<C&&(p+=G[i++]<<g,g+=8,g<C&&(p+=G[i++]<<g,g+=8)),I+=p&(1<<C)-1,I>l){t.msg="invalid distance too far back",r.mode=o0;break e}if(p>>>=C,g-=C,C=o-s,I>C){if(C=I-C,C>f&&r.sane){t.msg="invalid distance too far back",r.mode=o0;break e}if(D=0,M=d,h===0){if(D+=u-C,C<_){_-=C;do O[o++]=d[D++];while(--C);D=o-I,M=O}}else if(h<C){if(D+=u+h-C,C-=h,C<_){_-=C;do O[o++]=d[D++];while(--C);if(D=0,h<_){C=h,_-=C;do O[o++]=d[D++];while(--C);D=o-I,M=O}}}else if(D+=h-C,C<_){_-=C;do O[o++]=d[D++];while(--C);D=o-I,M=O}for(;_>2;)O[o++]=M[D++],O[o++]=M[D++],O[o++]=M[D++],_-=3;_&&(O[o++]=M[D++],_>1&&(O[o++]=M[D++]))}else{D=o-I;do O[o++]=O[D++],O[o++]=O[D++],O[o++]=O[D++],_-=3;while(_>2);_&&(O[o++]=O[D++],_>1&&(O[o++]=O[D++]))}}else if(C&64){t.msg="invalid distance code",r.mode=o0;break e}else{x=y[(x&65535)+(p&(1<<C)-1)];continue n}break}}else if(C&64)if(C&32){r.mode=eY;break e}else{t.msg="invalid literal/length code",r.mode=o0;break e}else{x=b[(x&65535)+(p&(1<<C)-1)];continue t}break}}while(i<a&&o<c);_=g>>3,i-=_,g-=_<<3,p&=(1<<g)-1,t.next_in=i,t.next_out=o,t.avail_in=i<a?5+(a-i):5-(i-a),t.avail_out=o<c?257+(c-o):257-(o-c),r.hold=p,r.bits=g},tC=Kr,Ls=15,nC=852,rC=592,iC=0,iy=1,aC=2,nY=[3,4,5,6,7,8,9,10,11,13,15,17,19,23,27,31,35,43,51,59,67,83,99,115,131,163,195,227,258,0,0],rY=[16,16,16,16,16,16,16,16,17,17,17,17,18,18,18,18,19,19,19,19,20,20,20,20,21,21,21,21,16,72,78],iY=[1,2,3,4,5,7,9,13,17,25,33,49,65,97,129,193,257,385,513,769,1025,1537,2049,3073,4097,6145,8193,12289,16385,24577,0,0],aY=[16,16,16,16,17,17,18,18,19,19,20,20,21,21,22,22,23,23,24,24,25,25,26,26,27,27,28,28,29,29,64,64],oY=function(t,n,r,i,a,o,s,c){var l=c.bits,u=0,f=0,h=0,d=0,p=0,g=0,b=0,y=0,w=0,A=0,x,C,_,I,D,M=null,G=0,O,ae=new tC.Buf16(Ls+1),se=new tC.Buf16(Ls+1),ve=null,Pe=0,st,Ne,lt;for(u=0;u<=Ls;u++)ae[u]=0;for(f=0;f<i;f++)ae[n[r+f]]++;for(p=l,d=Ls;d>=1&&ae[d]===0;d--);if(p>d&&(p=d),d===0)return a[o++]=1<<24|64<<16|0,a[o++]=1<<24|64<<16|0,c.bits=1,0;for(h=1;h<d&&ae[h]===0;h++);for(p<h&&(p=h),y=1,u=1;u<=Ls;u++)if(y<<=1,y-=ae[u],y<0)return-1;if(y>0&&(t===iC||d!==1))return-1;for(se[1]=0,u=1;u<Ls;u++)se[u+1]=se[u]+ae[u];for(f=0;f<i;f++)n[r+f]!==0&&(s[se[n[r+f]]++]=f);if(t===iC?(M=ve=s,O=19):t===iy?(M=nY,G-=257,ve=rY,Pe-=257,O=256):(M=iY,ve=aY,O=-1),A=0,f=0,u=h,D=o,g=p,b=0,_=-1,w=1<<p,I=w-1,t===iy&&w>nC||t===aC&&w>rC)return 1;for(;;){st=u-b,s[f]<O?(Ne=0,lt=s[f]):s[f]>O?(Ne=ve[Pe+s[f]],lt=M[G+s[f]]):(Ne=32+64,lt=0),x=1<<u-b,C=1<<g,h=C;do C-=x,a[D+(A>>b)+C]=st<<24|Ne<<16|lt|0;while(C!==0);for(x=1<<u-1;A&x;)x>>=1;if(x!==0?(A&=x-1,A+=x):A=0,f++,--ae[u]===0){if(u===d)break;u=n[r+s[f]]}if(u>p&&(A&I)!==_){for(b===0&&(b=p),D+=h,g=u-b,y=1<<g;g+b<d&&(y-=ae[g+b],!(y<=0));)g++,y<<=1;if(w+=1<<g,t===iy&&w>nC||t===aC&&w>rC)return 1;_=A&I,a[_]=p<<24|g<<16|D-o|0}}return A!==0&&(a[D+A]=u-b<<24|64<<16|0),c.bits=p,0},mn=Kr,ay=N6,Cr=z6,sY=tY,ku=oY,cY=0,oC=1,sC=2,cC=4,lY=5,s0=6,Ao=0,uY=1,fY=2,Tn=-2,lC=-3,uC=-4,hY=-5,fC=8,hC=1,dC=2,pC=3,gC=4,mC=5,bC=6,yC=7,vC=8,wC=9,xC=10,c0=11,ei=12,oy=13,AC=14,sy=15,EC=16,SC=17,_C=18,CC=19,l0=20,u0=21,kC=22,TC=23,IC=24,RC=25,DC=26,cy=27,BC=28,FC=29,Ke=30,PC=31,dY=32,pY=852,gY=592,mY=15,bY=mY;function MC(e){return(e>>>24&255)+(e>>>8&65280)+((e&65280)<<8)+((e&255)<<24)}function yY(){this.mode=0,this.last=!1,this.wrap=0,this.havedict=!1,this.flags=0,this.dmax=0,this.check=0,this.total=0,this.head=null,this.wbits=0,this.wsize=0,this.whave=0,this.wnext=0,this.window=null,this.hold=0,this.bits=0,this.length=0,this.offset=0,this.extra=0,this.lencode=null,this.distcode=null,this.lenbits=0,this.distbits=0,this.ncode=0,this.nlen=0,this.ndist=0,this.have=0,this.next=null,this.lens=new mn.Buf16(320),this.work=new mn.Buf16(288),this.lendyn=null,this.distdyn=null,this.sane=0,this.back=0,this.was=0}function OC(e){var t;return!e||!e.state?Tn:(t=e.state,e.total_in=e.total_out=t.total=0,e.msg="",t.wrap&&(e.adler=t.wrap&1),t.mode=hC,t.last=0,t.havedict=0,t.dmax=32768,t.head=null,t.hold=0,t.bits=0,t.lencode=t.lendyn=new mn.Buf32(pY),t.distcode=t.distdyn=new mn.Buf32(gY),t.sane=1,t.back=-1,Ao)}function LC(e){var t;return!e||!e.state?Tn:(t=e.state,t.wsize=0,t.whave=0,t.wnext=0,OC(e))}function NC(e,t){var n,r;return!e||!e.state||(r=e.state,t<0?(n=0,t=-t):(n=(t>>4)+1,t<48&&(t&=15)),t&&(t<8||t>15))?Tn:(r.window!==null&&r.wbits!==t&&(r.window=null),r.wrap=n,r.wbits=t,LC(e))}function zC(e,t){var n,r;return e?(r=new yY,e.state=r,r.window=null,n=NC(e,t),n!==Ao&&(e.state=null),n):Tn}function vY(e){return zC(e,bY)}var UC=!0,ly,uy;function wY(e){if(UC){var t;for(ly=new mn.Buf32(512),uy=new mn.Buf32(32),t=0;t<144;)e.lens[t++]=8;for(;t<256;)e.lens[t++]=9;for(;t<280;)e.lens[t++]=7;for(;t<288;)e.lens[t++]=8;for(ku(oC,e.lens,0,288,ly,0,e.work,{bits:9}),t=0;t<32;)e.lens[t++]=5;ku(sC,e.lens,0,32,uy,0,e.work,{bits:5}),UC=!1}e.lencode=ly,e.lenbits=9,e.distcode=uy,e.distbits=5}function $C(e,t,n,r){var i,a=e.state;return a.window===null&&(a.wsize=1<<a.wbits,a.wnext=0,a.whave=0,a.window=new mn.Buf8(a.wsize)),r>=a.wsize?(mn.arraySet(a.window,t,n-a.wsize,a.wsize,0),a.wnext=0,a.whave=a.wsize):(i=a.wsize-a.wnext,i>r&&(i=r),mn.arraySet(a.window,t,n-r,i,a.wnext),r-=i,r?(mn.arraySet(a.window,t,n-r,r,0),a.wnext=r,a.whave=a.wsize):(a.wnext+=i,a.wnext===a.wsize&&(a.wnext=0),a.whave<a.wsize&&(a.whave+=i))),0}function xY(e,t){var n,r,i,a,o,s,c,l,u,f,h,d,p,g,b=0,y,w,A,x,C,_,I,D,M=new mn.Buf8(4),G,O,ae=[16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15];if(!e||!e.state||!e.output||!e.input&&e.avail_in!==0)return Tn;n=e.state,n.mode===ei&&(n.mode=oy),o=e.next_out,i=e.output,c=e.avail_out,a=e.next_in,r=e.input,s=e.avail_in,l=n.hold,u=n.bits,f=s,h=c,D=Ao;e:for(;;)switch(n.mode){case hC:if(n.wrap===0){n.mode=oy;break}for(;u<16;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(n.wrap&2&&l===35615){n.check=0,M[0]=l&255,M[1]=l>>>8&255,n.check=Cr(n.check,M,2,0),l=0,u=0,n.mode=dC;break}if(n.flags=0,n.head&&(n.head.done=!1),!(n.wrap&1)||(((l&255)<<8)+(l>>8))%31){e.msg="incorrect header check",n.mode=Ke;break}if((l&15)!==fC){e.msg="unknown compression method",n.mode=Ke;break}if(l>>>=4,u-=4,I=(l&15)+8,n.wbits===0)n.wbits=I;else if(I>n.wbits){e.msg="invalid window size",n.mode=Ke;break}n.dmax=1<<I,e.adler=n.check=1,n.mode=l&512?xC:ei,l=0,u=0;break;case dC:for(;u<16;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(n.flags=l,(n.flags&255)!==fC){e.msg="unknown compression method",n.mode=Ke;break}if(n.flags&57344){e.msg="unknown header flags set",n.mode=Ke;break}n.head&&(n.head.text=l>>8&1),n.flags&512&&(M[0]=l&255,M[1]=l>>>8&255,n.check=Cr(n.check,M,2,0)),l=0,u=0,n.mode=pC;case pC:for(;u<32;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}n.head&&(n.head.time=l),n.flags&512&&(M[0]=l&255,M[1]=l>>>8&255,M[2]=l>>>16&255,M[3]=l>>>24&255,n.check=Cr(n.check,M,4,0)),l=0,u=0,n.mode=gC;case gC:for(;u<16;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}n.head&&(n.head.xflags=l&255,n.head.os=l>>8),n.flags&512&&(M[0]=l&255,M[1]=l>>>8&255,n.check=Cr(n.check,M,2,0)),l=0,u=0,n.mode=mC;case mC:if(n.flags&1024){for(;u<16;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}n.length=l,n.head&&(n.head.extra_len=l),n.flags&512&&(M[0]=l&255,M[1]=l>>>8&255,n.check=Cr(n.check,M,2,0)),l=0,u=0}else n.head&&(n.head.extra=null);n.mode=bC;case bC:if(n.flags&1024&&(d=n.length,d>s&&(d=s),d&&(n.head&&(I=n.head.extra_len-n.length,n.head.extra||(n.head.extra=new Array(n.head.extra_len)),mn.arraySet(n.head.extra,r,a,d,I)),n.flags&512&&(n.check=Cr(n.check,r,d,a)),s-=d,a+=d,n.length-=d),n.length))break e;n.length=0,n.mode=yC;case yC:if(n.flags&2048){if(s===0)break e;d=0;do I=r[a+d++],n.head&&I&&n.length<65536&&(n.head.name+=String.fromCharCode(I));while(I&&d<s);if(n.flags&512&&(n.check=Cr(n.check,r,d,a)),s-=d,a+=d,I)break e}else n.head&&(n.head.name=null);n.length=0,n.mode=vC;case vC:if(n.flags&4096){if(s===0)break e;d=0;do I=r[a+d++],n.head&&I&&n.length<65536&&(n.head.comment+=String.fromCharCode(I));while(I&&d<s);if(n.flags&512&&(n.check=Cr(n.check,r,d,a)),s-=d,a+=d,I)break e}else n.head&&(n.head.comment=null);n.mode=wC;case wC:if(n.flags&512){for(;u<16;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(l!==(n.check&65535)){e.msg="header crc mismatch",n.mode=Ke;break}l=0,u=0}n.head&&(n.head.hcrc=n.flags>>9&1,n.head.done=!0),e.adler=n.check=0,n.mode=ei;break;case xC:for(;u<32;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}e.adler=n.check=MC(l),l=0,u=0,n.mode=c0;case c0:if(n.havedict===0)return e.next_out=o,e.avail_out=c,e.next_in=a,e.avail_in=s,n.hold=l,n.bits=u,fY;e.adler=n.check=1,n.mode=ei;case ei:if(t===lY||t===s0)break e;case oy:if(n.last){l>>>=u&7,u-=u&7,n.mode=cy;break}for(;u<3;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}switch(n.last=l&1,l>>>=1,u-=1,l&3){case 0:n.mode=AC;break;case 1:if(wY(n),n.mode=l0,t===s0){l>>>=2,u-=2;break e}break;case 2:n.mode=SC;break;case 3:e.msg="invalid block type",n.mode=Ke}l>>>=2,u-=2;break;case AC:for(l>>>=u&7,u-=u&7;u<32;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if((l&65535)!==(l>>>16^65535)){e.msg="invalid stored block lengths",n.mode=Ke;break}if(n.length=l&65535,l=0,u=0,n.mode=sy,t===s0)break e;case sy:n.mode=EC;case EC:if(d=n.length,d){if(d>s&&(d=s),d>c&&(d=c),d===0)break e;mn.arraySet(i,r,a,d,o),s-=d,a+=d,c-=d,o+=d,n.length-=d;break}n.mode=ei;break;case SC:for(;u<14;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(n.nlen=(l&31)+257,l>>>=5,u-=5,n.ndist=(l&31)+1,l>>>=5,u-=5,n.ncode=(l&15)+4,l>>>=4,u-=4,n.nlen>286||n.ndist>30){e.msg="too many length or distance symbols",n.mode=Ke;break}n.have=0,n.mode=_C;case _C:for(;n.have<n.ncode;){for(;u<3;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}n.lens[ae[n.have++]]=l&7,l>>>=3,u-=3}for(;n.have<19;)n.lens[ae[n.have++]]=0;if(n.lencode=n.lendyn,n.lenbits=7,G={bits:n.lenbits},D=ku(cY,n.lens,0,19,n.lencode,0,n.work,G),n.lenbits=G.bits,D){e.msg="invalid code lengths set",n.mode=Ke;break}n.have=0,n.mode=CC;case CC:for(;n.have<n.nlen+n.ndist;){for(;b=n.lencode[l&(1<<n.lenbits)-1],y=b>>>24,w=b>>>16&255,A=b&65535,!(y<=u);){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(A<16)l>>>=y,u-=y,n.lens[n.have++]=A;else{if(A===16){for(O=y+2;u<O;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(l>>>=y,u-=y,n.have===0){e.msg="invalid bit length repeat",n.mode=Ke;break}I=n.lens[n.have-1],d=3+(l&3),l>>>=2,u-=2}else if(A===17){for(O=y+3;u<O;){if(s===0)break 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r;return(r=(await this._getIndexes(n)).name[t])===null||r===void 0?void 0:r.length}async hasReferenceSequence(t,n){return!!(await this._getIndexes(n)).name[t]}async getResiduesById(t,n,r,i){const a=(await this._getIndexes(i)).id[t];if(a)return this._fetchFromIndexEntry(a,n,r,i)}async getResiduesByName(t,n,r,i){const a=(await this._getIndexes(i)).name[t];if(a)return this._fetchFromIndexEntry(a,n,r,i)}async getSequence(t,n,r,i){return this.getResiduesByName(t,n,r,i)}async _fetchFromIndexEntry(t,n=0,r,i){let a=r;if(n<0)throw new TypeError("regionStart cannot be less than 0");if((a===void 0||a>t.length)&&(a=t.length),n>=a)return"";const o=n5(t,n),s=n5(t,a)-o;if(s>this.chunkSizeLimit)throw new Error(`data size of ${s.toLocaleString()} bytes exceeded chunk size limit of ${this.chunkSizeLimit.toLocaleString()} bytes`);const c=Buffer.allocUnsafe(s);return await this.fasta.read(c,0,s,o,i),c.toString("utf8").replace(/\s+/g,"")}}class NY extends r5{constructor({fasta:t,path:n,fai:r,faiPath:i,gzi:a,gziPath:o,chunkSizeLimit:s}){super({fasta:t,path:n,fai:r,faiPath:i,chunkSizeLimit:s}),t&&a?this.fasta=new t5({filehandle:t,gziFilehandle:a}):n&&o&&(this.fasta=new t5({path:n,gziPath:o}))}}function i5(e){return e.split(">").filter(t=>/\S/.test(t)).map(t=>{const[n,...r]=t.split(`
|
|
3272
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-
`),[i,...a]=n.split(" "),o=r.join("").replace(/\s/g,"");return{id:i,description:a.join(" "),sequence:o}})}class
|
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3273
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-
`}pushPath(t){t&&this.scopes[this.scopes.length-1].push(t)}popPath(t){t&&this.scopes[this.scopes.length-1].pop()}pushScope(t){this.scopes.push([t])}popScope(){this.scopes.pop()}addImport(t){if(!this.importPath)return`(${t})`;let n=this.reverseImports.get(t);return n||(n=this.imports.push(t)-1,this.reverseImports.set(t,n)),`${this.importPath}[${n}]`}addReference(t){this.references.has(t)||this.references.set(t,{resolved:!1,requested:!1})}markResolved(t){const n=this.references.get(t);n&&(n.resolved=!0)}markRequested(t){t.forEach(n=>{const r=this.references.get(n);r&&(r.requested=!0)})}getUnresolvedReferences(){return Array.from(this.references).filter(([t,n])=>!n.resolved&&!n.requested).map(([t,n])=>t)}}const rr=new 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this.bitN(2,t,n)}bit3(t,n={}){return this.bitN(3,t,n)}bit4(t,n={}){return this.bitN(4,t,n)}bit5(t,n={}){return this.bitN(5,t,n)}bit6(t,n={}){return this.bitN(6,t,n)}bit7(t,n={}){return this.bitN(7,t,n)}bit8(t,n={}){return this.bitN(8,t,n)}bit9(t,n={}){return this.bitN(9,t,n)}bit10(t,n={}){return this.bitN(10,t,n)}bit11(t,n={}){return this.bitN(11,t,n)}bit12(t,n={}){return this.bitN(12,t,n)}bit13(t,n={}){return this.bitN(13,t,n)}bit14(t,n={}){return this.bitN(14,t,n)}bit15(t,n={}){return this.bitN(15,t,n)}bit16(t,n={}){return this.bitN(16,t,n)}bit17(t,n={}){return this.bitN(17,t,n)}bit18(t,n={}){return this.bitN(18,t,n)}bit19(t,n={}){return this.bitN(19,t,n)}bit20(t,n={}){return this.bitN(20,t,n)}bit21(t,n={}){return this.bitN(21,t,n)}bit22(t,n={}){return this.bitN(22,t,n)}bit23(t,n={}){return this.bitN(23,t,n)}bit24(t,n={}){return this.bitN(24,t,n)}bit25(t,n={}){return this.bitN(25,t,n)}bit26(t,n={}){return this.bitN(26,t,n)}bit27(t,n={}){return this.bitN(27,t,n)}bit28(t,n={}){return this.bitN(28,t,n)}bit29(t,n={}){return this.bitN(29,t,n)}bit30(t,n={}){return this.bitN(30,t,n)}bit31(t,n={}){return this.bitN(31,t,n)}bit32(t,n={}){return this.bitN(32,t,n)}namely(t){return rr.set(t,this),this.alias=t,this}skip(t,n={}){return this.seek(t,n)}seek(t,n={}){if(n.assert)throw new Error("assert option on seek is not allowed.");return this.setNextParser("seek","",{length:t})}string(t,n){if(!n.zeroTerminated&&!n.length&&!n.greedy)throw new Error("One of length, zeroTerminated, or greedy must be defined for string.");if((n.zeroTerminated||n.length)&&n.greedy)throw new Error("greedy is mutually exclusive with length and zeroTerminated for string.");if(n.stripNull&&!(n.length||n.greedy))throw new Error("length or greedy must be defined if stripNull is enabled.");return n.encoding=n.encoding||"utf8",this.setNextParser("string",t,n)}buffer(t,n){if(!n.length&&!n.readUntil)throw new Error("length or readUntil must be defined for buffer.");return 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i=parseInt(r,10),a=n.choices[i];if(isNaN(i))throw new Error(`Choice key "${r}" is not a number.`);if(typeof a=="string"&&!rr.has(a)&&!(a in ir))throw new Error(`Choice type "${a}" is unkown.`)}return this.setNextParser("choice",t,n)}nest(t,n){if(typeof n!="object"&&typeof t=="object"&&(n=t,t=""),!n||!n.type)throw new Error("type is required for nest.");if(!(n.type instanceof sr)&&!rr.has(n.type))throw new Error("type must be a known parser name or a Parser object.");if(!(n.type instanceof sr)&&!t)throw new Error("type must be a Parser object if the variable name is omitted.");return this.setNextParser("nest",t,n)}pointer(t,n){if(!n.offset)throw new Error("offset is required for pointer.");if(!n.type)throw new Error("type is required for pointer.");if(typeof n.type=="string"&&!(n.type in ir)&&!rr.has(n.type))throw new Error(`Pointer type "${n.type}" is unkown.`);return this.setNextParser("pointer",t,n)}saveOffset(t,n={}){return this.setNextParser("saveOffset",t,n)}endianness(t){switch(t.toLowerCase()){case"little":this.endian="le";break;case"big":this.endian="be";break;default:throw new Error('endianness must be one of "little" or "big"')}return this}endianess(t){return this.endianness(t)}useContextVars(t=!0){return this.useContextVariables=t,this}create(t){if(!(t instanceof Function))throw new Error("Constructor must be a Function object.");return this.constructorFn=t,this}getContext(t){const n=new jY(t,this.useContextVariables);return n.pushCode("var dataView = new DataView(buffer.buffer, buffer.byteOffset, buffer.length);"),this.alias?(this.addAliasedCode(n),n.pushCode(`return ${Co+this.alias}(0).result;`)):this.addRawCode(n),n}getCode(){const t="imports";return this.getContext(t).code}addRawCode(t){t.pushCode("var offset = 0;"),t.pushCode(`var vars = ${this.constructorFn?"new constructorFn()":"{}"};`),t.pushCode("vars.$parent = null;"),t.pushCode("vars.$root = vars;"),this.generate(t),this.resolveReferences(t),t.pushCode("delete vars.$parent;"),t.pushCode("delete vars.$root;"),t.pushCode("return vars;")}addAliasedCode(t){return t.pushCode(`function ${Co+this.alias}(offset, context) {`),t.pushCode(`var vars = ${this.constructorFn?"new constructorFn()":"{}"};`),t.pushCode("var ctx = Object.assign({$parent: null, $root: vars}, context || {});"),t.pushCode("vars = Object.assign(vars, ctx);"),this.generate(t),t.markResolved(this.alias),this.resolveReferences(t),t.pushCode("Object.keys(ctx).forEach(function (item) { delete vars[item]; });"),t.pushCode("return { offset: offset, result: vars };"),t.pushCode("}"),t}resolveReferences(t){const n=t.getUnresolvedReferences();t.markRequested(n),n.forEach(r=>{var i;(i=rr.get(r))===null||i===void 0||i.addAliasedCode(t)})}compile(){const t="imports",n=this.getContext(t);this.compiled=new Function(t,"TextDecoder",`return function (buffer, constructorFn) { ${n.code} };`)(n.imports,TextDecoder)}sizeOf(){let t=NaN;if(Object.keys(ir).indexOf(this.type)>=0)t=ir[this.type];else if(this.type==="string"&&typeof this.options.length=="number")t=this.options.length;else if(this.type==="buffer"&&typeof this.options.length=="number")t=this.options.length;else if(this.type==="array"&&typeof this.options.length=="number"){let n=NaN;typeof this.options.type=="string"?n=ir[this.options.type]:this.options.type instanceof sr&&(n=this.options.type.sizeOf()),t=this.options.length*n}else this.type==="seek"?t=this.options.length:this.type==="nest"?t=this.options.type.sizeOf():this.type||(t=0);return this.next&&(t+=this.next.sizeOf()),t}parse(t){return this.compiled||this.compile(),this.compiled(t,this.constructorFn)}setNextParser(t,n,r){const i=new sr;return i.type=t,i.varName=n,i.options=r,i.endian=this.endian,this.head?this.head.next=i:this.next=i,this.head=i,this}generate(t){if(this.type){switch(this.type){case"uint8":case"uint16le":case"uint16be":case"uint32le":case"uint32be":case"int8":case"int16le":case"int16be":case"int32le":case"int32be":case"int64be":case"int64le":case"uint64be":case"uint64le":case"floatle":case"floatbe":case"doublele":case"doublebe":this.primitiveGenerateN(this.type,t);break;case"bit":this.generateBit(t);break;case"string":this.generateString(t);break;case"buffer":this.generateBuffer(t);break;case"seek":this.generateSeek(t);break;case"nest":this.generateNest(t);break;case"array":this.generateArray(t);break;case"choice":this.generateChoice(t);break;case"pointer":this.generatePointer(t);break;case"saveOffset":this.generateSaveOffset(t);break;case"wrapper":this.generateWrapper(t);break}this.type!=="bit"&&this.generateAssert(t)}const n=t.generateVariable(this.varName);return this.options.formatter&&this.type!=="bit"&&this.generateFormatter(t,n,this.options.formatter),this.generateNext(t)}generateAssert(t){if(!this.options.assert)return;const n=t.generateVariable(this.varName);switch(typeof this.options.assert){case"function":{const r=t.addImport(this.options.assert);t.pushCode(`if (!${r}.call(vars, ${n})) {`)}break;case"number":t.pushCode(`if (${this.options.assert} !== ${n}) {`);break;case"string":t.pushCode(`if (${JSON.stringify(this.options.assert)} !== ${n}) {`);break;default:throw new Error("assert option must be a string, number or a function.")}t.generateError(`"Assertion error: ${n} is " + ${JSON.stringify(this.options.assert.toString())}`),t.pushCode("}")}generateNext(t){return this.next&&(t=this.next.generate(t)),t}generateBit(t){const n=JSON.parse(JSON.stringify(this));if(n.options=this.options,n.generateAssert=this.generateAssert.bind(this),n.generateFormatter=this.generateFormatter.bind(this),n.varName=t.generateVariable(n.varName),t.bitFields.push(n),!this.next||this.next&&["bit","nest"].indexOf(this.next.type)<0){const r=t.generateTmpVariable();t.pushCode(`var ${r} = 0;`);const i=(u=0)=>{let f=0;for(let h=u;h<t.bitFields.length;h++){const d=t.bitFields[h].options.length;if(f+d>32)break;f+=d}return f},a=u=>(u<=8?(t.pushCode(`${r} = dataView.getUint8(offset);`),u=8):u<=16?(t.pushCode(`${r} = dataView.getUint16(offset);`),u=16):u<=24?(t.pushCode(`${r} = (dataView.getUint16(offset) << 8) | dataView.getUint8(offset + 2);`),u=24):(t.pushCode(`${r} = dataView.getUint32(offset);`),u=32),t.pushCode(`offset += ${u/8};`),u);let o=0;const s=this.endian==="be";let c=0,l=0;t.bitFields.forEach((u,f)=>{let h=u.options.length;if(h>l){if(l){const g=-1>>>32-l;t.pushCode(`${u.varName} = (${r} & 0x${g.toString(16)}) << 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n=t.generateVariable(this.varName);if(typeof this.options.readUntil=="function"){const r=this.options.readUntil,i=t.generateTmpVariable(),a=t.generateTmpVariable();t.pushCode(`var ${i} = offset;`),t.pushCode(`var ${a} = 0;`),t.pushCode("while (offset < buffer.length) {"),t.pushCode(`${a} = dataView.getUint8(offset);`);const o=t.addImport(r);t.pushCode(`if (${o}.call(${t.generateVariable()}, ${a}, buffer.subarray(offset))) break;`),t.pushCode("offset += 1;"),t.pushCode("}"),t.pushCode(`${n} = buffer.subarray(${i}, offset);`)}else if(this.options.readUntil==="eof")t.pushCode(`${n} = buffer.subarray(offset);`);else{const r=t.generateOption(this.options.length);t.pushCode(`${n} = buffer.subarray(offset, offset + ${r});`),t.pushCode(`offset += ${r};`)}this.options.clone&&t.pushCode(`${n} = buffer.constructor.from(${n});`)}generateArray(t){const n=t.generateOption(this.options.length),r=t.generateOption(this.options.lengthInBytes),i=this.options.type,a=t.generateTmpVariable(),o=t.generateVariable(this.varName),s=t.generateTmpVariable(),c=this.options.key,l=typeof c=="string";if(l?t.pushCode(`${o} = {};`):t.pushCode(`${o} = [];`),typeof this.options.readUntil=="function"?t.pushCode("do {"):this.options.readUntil==="eof"?t.pushCode(`for (var ${a} = 0; offset < buffer.length; ${a}++) {`):r!==void 0?t.pushCode(`for (var ${a} = offset + ${r}; offset < ${a}; ) {`):t.pushCode(`for (var ${a} = ${n}; ${a} > 0; ${a}--) {`),typeof i=="string")if(rr.get(i)){const u=t.generateTmpVariable();if(t.pushCode(`var ${u} = ${Co+i}(offset, {`),t.useContextVariables){const f=t.generateVariable();t.pushCode(`$parent: ${f},`),t.pushCode(`$root: ${f}.$root,`),!this.options.readUntil&&r===void 0&&t.pushCode(`$index: ${n} - ${a},`)}t.pushCode("});"),t.pushCode(`var ${s} = ${u}.result; offset = ${u}.offset;`),i!==this.alias&&t.addReference(i)}else{const u=b0[i],f=y0[i];t.pushCode(`var ${s} = dataView.get${u}(offset, ${f});`),t.pushCode(`offset += ${ir[i]};`)}else if(i instanceof sr){t.pushCode(`var ${s} = {};`);const u=t.generateVariable();t.pushScope(s),t.useContextVariables&&(t.pushCode(`${s}.$parent = ${u};`),t.pushCode(`${s}.$root = ${u}.$root;`),!this.options.readUntil&&r===void 0&&t.pushCode(`${s}.$index = ${n} - ${a};`)),i.generate(t),t.useContextVariables&&(t.pushCode(`delete ${s}.$parent;`),t.pushCode(`delete ${s}.$root;`),t.pushCode(`delete ${s}.$index;`)),t.popScope()}if(l?t.pushCode(`${o}[${s}.${c}] = ${s};`):t.pushCode(`${o}.push(${s});`),t.pushCode("}"),typeof this.options.readUntil=="function"){const u=this.options.readUntil,f=t.addImport(u);t.pushCode(`while (!${f}.call(${t.generateVariable()}, ${s}, buffer.subarray(offset)));`)}}generateChoiceCase(t,n,r){if(typeof r=="string"){const i=t.generateVariable(this.varName);if(rr.has(r)){const a=t.generateTmpVariable();t.pushCode(`var ${a} = ${Co+r}(offset, 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undefined tag value " + ${n} + " at choice"`),t.pushCode("}"),this.varName&&t.useContextVariables&&(t.pushCode(`delete ${r}.$parent;`),t.pushCode(`delete ${r}.$root;`))}generateNest(t){const n=t.generateVariable(this.varName);if(this.options.type instanceof sr){if(this.varName&&(t.pushCode(`${n} = {};`),t.useContextVariables)){const r=t.generateVariable();t.pushCode(`${n}.$parent = ${r};`),t.pushCode(`${n}.$root = ${r}.$root;`)}t.pushPath(this.varName),this.options.type.generate(t),t.popPath(this.varName),this.varName&&t.useContextVariables&&t.useContextVariables&&(t.pushCode(`delete ${n}.$parent;`),t.pushCode(`delete ${n}.$root;`))}else if(rr.has(this.options.type)){const r=t.generateTmpVariable();if(t.pushCode(`var ${r} = ${Co+this.options.type}(offset, {`),t.useContextVariables){const i=t.generateVariable();t.pushCode(`$parent: ${i},`),t.pushCode(`$root: ${i}.$root,`)}t.pushCode("});"),t.pushCode(`${n} = ${r}.result; offset = ${r}.offset;`),this.options.type!==this.alias&&t.addReference(this.options.type)}}generateWrapper(t){const n=t.generateVariable(this.varName),r=t.generateTmpVariable();if(typeof this.options.readUntil=="function"){const c=this.options.readUntil,l=t.generateTmpVariable(),u=t.generateTmpVariable();t.pushCode(`var ${l} = offset;`),t.pushCode(`var ${u} = 0;`),t.pushCode("while (offset < buffer.length) {"),t.pushCode(`${u} = dataView.getUint8(offset);`);const f=t.addImport(c);t.pushCode(`if (${f}.call(${t.generateVariable()}, ${u}, buffer.subarray(offset))) break;`),t.pushCode("offset += 1;"),t.pushCode("}"),t.pushCode(`${r} = buffer.subarray(${l}, offset);`)}else if(this.options.readUntil==="eof")t.pushCode(`${r} = buffer.subarray(offset);`);else{const c=t.generateOption(this.options.length);t.pushCode(`${r} = buffer.subarray(offset, offset + ${c});`),t.pushCode(`offset += ${c};`)}this.options.clone&&t.pushCode(`${r} = buffer.constructor.from(${r});`);const i=t.generateTmpVariable(),a=t.generateTmpVariable(),o=t.generateTmpVariable(),s=t.addImport(this.options.wrapper);if(t.pushCode(`${r} = ${s}.call(this, ${r}).subarray(0);`),t.pushCode(`var ${i} = buffer;`),t.pushCode(`var ${a} = offset;`),t.pushCode(`var ${o} = dataView;`),t.pushCode(`buffer = ${r};`),t.pushCode("offset = 0;"),t.pushCode("dataView = new DataView(buffer.buffer, buffer.byteOffset, buffer.length);"),this.options.type instanceof sr)this.varName&&t.pushCode(`${n} = {};`),t.pushPath(this.varName),this.options.type.generate(t),t.popPath(this.varName);else if(rr.has(this.options.type)){const c=t.generateTmpVariable();t.pushCode(`var ${c} = ${Co+this.options.type}(0);`),t.pushCode(`${n} = ${c}.result;`),this.options.type!==this.alias&&t.addReference(this.options.type)}t.pushCode(`buffer = ${i};`),t.pushCode(`dataView = ${o};`),t.pushCode(`offset = ${a};`)}generateFormatter(t,n,r){if(typeof r=="function"){const i=t.addImport(r);t.pushCode(`${n} = ${i}.call(${t.generateVariable()}, ${n});`)}}generatePointer(t){const n=this.options.type,r=t.generateOption(this.options.offset),i=t.generateTmpVariable(),a=t.generateVariable(this.varName);if(t.pushCode(`var ${i} = offset;`),t.pushCode(`offset = ${r};`),this.options.type instanceof sr){if(t.pushCode(`${a} = {};`),t.useContextVariables){const o=t.generateVariable();t.pushCode(`${a}.$parent = ${o};`),t.pushCode(`${a}.$root = ${o}.$root;`)}t.pushPath(this.varName),this.options.type.generate(t),t.popPath(this.varName),t.useContextVariables&&(t.pushCode(`delete ${a}.$parent;`),t.pushCode(`delete ${a}.$root;`))}else if(rr.has(this.options.type)){const o=t.generateTmpVariable();if(t.pushCode(`var ${o} = ${Co+this.options.type}(offset, {`),t.useContextVariables){const s=t.generateVariable();t.pushCode(`$parent: ${s},`),t.pushCode(`$root: ${s}.$root,`)}t.pushCode("});"),t.pushCode(`${a} = ${o}.result; offset = 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Iy(e.bl_tree,x5),e.bi_buf=0,e.bi_valid=0,_5(e)},B5=(e,t,n,r)=>{cn(e,(pZ<<1)+(r?1:0),3),C5(e),Ou(e,n),Ou(e,~n),n&&e.pending_buf.set(e.window.subarray(t,t+n),e.pending),e.pending+=n},TZ=e=>{cn(e,d5<<1,3),kr(e,_y,ti),xZ(e)},IZ=(e,t,n,r)=>{let i,a,o=0;e.level>0?(e.strm.data_type===dZ&&(e.strm.data_type=CZ(e)),Dy(e,e.l_desc),Dy(e,e.d_desc),o=SZ(e),i=e.opt_len+3+7>>>3,a=e.static_len+3+7>>>3,a<=i&&(i=a)):i=a=n+5,n+4<=i&&t!==-1?B5(e,t,n,r):e.strategy===hZ||a===i?(cn(e,(d5<<1)+(r?1:0),3),T5(e,ti,Fu)):(cn(e,(gZ<<1)+(r?1:0),3),_Z(e,e.l_desc.max_code+1,e.d_desc.max_code+1,o+1),T5(e,e.dyn_ltree,e.dyn_dtree)),_5(e),r&&C5(e)},RZ=(e,t,n)=>(e.pending_buf[e.sym_buf+e.sym_next++]=t,e.pending_buf[e.sym_buf+e.sym_next++]=t>>8,e.pending_buf[e.sym_buf+e.sym_next++]=n,t===0?e.dyn_ltree[n*2]++:(e.matches++,t--,e.dyn_ltree[(Mu[n]+Du+1)*2]++,e.dyn_dtree[A5(t)*2]++),e.sym_next===e.sym_end);var DZ=kZ,BZ=B5,FZ=IZ,PZ=RZ,MZ=TZ,OZ={_tr_init:DZ,_tr_stored_block:BZ,_tr_flush_block:FZ,_tr_tally:PZ,_tr_align:MZ},Lu=(e,t,n,r)=>{let i=e&65535|0,a=e>>>16&65535|0,o=0;for(;n!==0;){o=n>2e3?2e3:n,n-=o;do i=i+t[r++]|0,a=a+i|0;while(--o);i%=65521,a%=65521}return i|a<<16|0};const LZ=()=>{let e,t=[];for(var n=0;n<256;n++){e=n;for(var r=0;r<8;r++)e=e&1?3988292384^e>>>1:e>>>1;t[n]=e}return t},NZ=new Uint32Array(LZ());var Tt=(e,t,n,r)=>{const i=NZ,a=r+n;e^=-1;for(let o=r;o<a;o++)e=e>>>8^i[(e^t[o])&255];return e^-1},Vs={2:"need dictionary",1:"stream end",0:"","-1":"file error","-2":"stream error","-3":"data error","-4":"insufficient memory","-5":"buffer error","-6":"incompatible version"},Nu={Z_NO_FLUSH:0,Z_PARTIAL_FLUSH:1,Z_SYNC_FLUSH:2,Z_FULL_FLUSH:3,Z_FINISH:4,Z_BLOCK:5,Z_TREES:6,Z_OK:0,Z_STREAM_END:1,Z_NEED_DICT:2,Z_ERRNO:-1,Z_STREAM_ERROR:-2,Z_DATA_ERROR:-3,Z_MEM_ERROR:-4,Z_BUF_ERROR:-5,Z_NO_COMPRESSION:0,Z_BEST_SPEED:1,Z_BEST_COMPRESSION:9,Z_DEFAULT_COMPRESSION:-1,Z_FILTERED:1,Z_HUFFMAN_ONLY:2,Z_RLE:3,Z_FIXED:4,Z_DEFAULT_STRATEGY:0,Z_BINARY:0,Z_TEXT:1,Z_UNKNOWN:2,Z_DEFLATED:8};const{_tr_init:zZ,_tr_stored_block:By,_tr_flush_block:UZ,_tr_tally:na,_tr_align:$Z}=OZ,{Z_NO_FLUSH:ra,Z_PARTIAL_FLUSH:HZ,Z_FULL_FLUSH:GZ,Z_FINISH:Bn,Z_BLOCK:F5,Z_OK:Mt,Z_STREAM_END:P5,Z_STREAM_ERROR:Tr,Z_DATA_ERROR:VZ,Z_BUF_ERROR:Fy,Z_DEFAULT_COMPRESSION:jZ,Z_FILTERED:qZ,Z_HUFFMAN_ONLY:C0,Z_RLE:WZ,Z_FIXED:YZ,Z_DEFAULT_STRATEGY:ZZ,Z_UNKNOWN:QZ,Z_DEFLATED:k0}=Nu,XZ=9,KZ=15,JZ=8,eQ=29,Py=256+1+eQ,tQ=30,nQ=19,rQ=2*Py+1,iQ=15,ye=3,ia=258,Ir=ia+ye+1,aQ=32,js=42,My=57,Oy=69,Ly=73,Ny=91,zy=103,Io=113,zu=666,Yt=1,qs=2,Ro=3,Ws=4,oQ=3,Do=(e,t)=>(e.msg=Vs[t],t),M5=e=>e*2-(e>4?9:0),aa=e=>{let t=e.length;for(;--t>=0;)e[t]=0},sQ=e=>{let t,n,r,i=e.w_size;t=e.hash_size,r=t;do n=e.head[--r],e.head[r]=n>=i?n-i:0;while(--t);t=i,r=t;do n=e.prev[--r],e.prev[r]=n>=i?n-i:0;while(--t)};let oa=(e,t,n)=>(t<<e.hash_shift^n)&e.hash_mask;const bn=e=>{const t=e.state;let n=t.pending;n>e.avail_out&&(n=e.avail_out),n!==0&&(e.output.set(t.pending_buf.subarray(t.pending_out,t.pending_out+n),e.next_out),e.next_out+=n,t.pending_out+=n,e.total_out+=n,e.avail_out-=n,t.pending-=n,t.pending===0&&(t.pending_out=0))},yn=(e,t)=>{UZ(e,e.block_start>=0?e.block_start:-1,e.strstart-e.block_start,t),e.block_start=e.strstart,bn(e.strm)},Ce=(e,t)=>{e.pending_buf[e.pending++]=t},Uu=(e,t)=>{e.pending_buf[e.pending++]=t>>>8&255,e.pending_buf[e.pending++]=t&255},Uy=(e,t,n,r)=>{let i=e.avail_in;return i>r&&(i=r),i===0?0:(e.avail_in-=i,t.set(e.input.subarray(e.next_in,e.next_in+i),n),e.state.wrap===1?e.adler=Lu(e.adler,t,i,n):e.state.wrap===2&&(e.adler=Tt(e.adler,t,i,n)),e.next_in+=i,e.total_in+=i,i)},O5=(e,t)=>{let n=e.max_chain_length,r=e.strstart,i,a,o=e.prev_length,s=e.nice_match;const c=e.strstart>e.w_size-Ir?e.strstart-(e.w_size-Ir):0,l=e.window,u=e.w_mask,f=e.prev,h=e.strstart+ia;let d=l[r+o-1],p=l[r+o];e.prev_length>=e.good_match&&(n>>=2),s>e.lookahead&&(s=e.lookahead);do if(i=t,!(l[i+o]!==p||l[i+o-1]!==d||l[i]!==l[r]||l[++i]!==l[r+1])){r+=2,i++;do;while(l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&r<h);if(a=ia-(h-r),r=h-ia,a>o){if(e.match_start=t,o=a,a>=s)break;d=l[r+o-1],p=l[r+o]}}while((t=f[t&u])>c&&--n!==0);return o<=e.lookahead?o:e.lookahead},Ys=e=>{const t=e.w_size;let n,r,i;do{if(r=e.window_size-e.lookahead-e.strstart,e.strstart>=t+(t-Ir)&&(e.window.set(e.window.subarray(t,t+t-r),0),e.match_start-=t,e.strstart-=t,e.block_start-=t,e.insert>e.strstart&&(e.insert=e.strstart),sQ(e),r+=t),e.strm.avail_in===0)break;if(n=Uy(e.strm,e.window,e.strstart+e.lookahead,r),e.lookahead+=n,e.lookahead+e.insert>=ye)for(i=e.strstart-e.insert,e.ins_h=e.window[i],e.ins_h=oa(e,e.ins_h,e.window[i+1]);e.insert&&(e.ins_h=oa(e,e.ins_h,e.window[i+ye-1]),e.prev[i&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=i,i++,e.insert--,!(e.lookahead+e.insert<ye)););}while(e.lookahead<Ir&&e.strm.avail_in!==0)},L5=(e,t)=>{let n=e.pending_buf_size-5>e.w_size?e.w_size:e.pending_buf_size-5,r,i,a,o=0,s=e.strm.avail_in;do{if(r=65535,a=e.bi_valid+42>>3,e.strm.avail_out<a||(a=e.strm.avail_out-a,i=e.strstart-e.block_start,r>i+e.strm.avail_in&&(r=i+e.strm.avail_in),r>a&&(r=a),r<n&&(r===0&&t!==Bn||t===ra||r!==i+e.strm.avail_in)))break;o=t===Bn&&r===i+e.strm.avail_in?1:0,By(e,0,0,o),e.pending_buf[e.pending-4]=r,e.pending_buf[e.pending-3]=r>>8,e.pending_buf[e.pending-2]=~r,e.pending_buf[e.pending-1]=~r>>8,bn(e.strm),i&&(i>r&&(i=r),e.strm.output.set(e.window.subarray(e.block_start,e.block_start+i),e.strm.next_out),e.strm.next_out+=i,e.strm.avail_out-=i,e.strm.total_out+=i,e.block_start+=i,r-=i),r&&(Uy(e.strm,e.strm.output,e.strm.next_out,r),e.strm.next_out+=r,e.strm.avail_out-=r,e.strm.total_out+=r)}while(o===0);return s-=e.strm.avail_in,s&&(s>=e.w_size?(e.matches=2,e.window.set(e.strm.input.subarray(e.strm.next_in-e.w_size,e.strm.next_in),0),e.strstart=e.w_size,e.insert=e.strstart):(e.window_size-e.strstart<=s&&(e.strstart-=e.w_size,e.window.set(e.window.subarray(e.w_size,e.w_size+e.strstart),0),e.matches<2&&e.matches++,e.insert>e.strstart&&(e.insert=e.strstart)),e.window.set(e.strm.input.subarray(e.strm.next_in-s,e.strm.next_in),e.strstart),e.strstart+=s,e.insert+=s>e.w_size-e.insert?e.w_size-e.insert:s),e.block_start=e.strstart),e.high_water<e.strstart&&(e.high_water=e.strstart),o?Ws:t!==ra&&t!==Bn&&e.strm.avail_in===0&&e.strstart===e.block_start?qs:(a=e.window_size-e.strstart,e.strm.avail_in>a&&e.block_start>=e.w_size&&(e.block_start-=e.w_size,e.strstart-=e.w_size,e.window.set(e.window.subarray(e.w_size,e.w_size+e.strstart),0),e.matches<2&&e.matches++,a+=e.w_size,e.insert>e.strstart&&(e.insert=e.strstart)),a>e.strm.avail_in&&(a=e.strm.avail_in),a&&(Uy(e.strm,e.window,e.strstart,a),e.strstart+=a,e.insert+=a>e.w_size-e.insert?e.w_size-e.insert:a),e.high_water<e.strstart&&(e.high_water=e.strstart),a=e.bi_valid+42>>3,a=e.pending_buf_size-a>65535?65535:e.pending_buf_size-a,n=a>e.w_size?e.w_size:a,i=e.strstart-e.block_start,(i>=n||(i||t===Bn)&&t!==ra&&e.strm.avail_in===0&&i<=a)&&(r=i>a?a:i,o=t===Bn&&e.strm.avail_in===0&&r===i?1:0,By(e,e.block_start,r,o),e.block_start+=r,bn(e.strm)),o?Ro:Yt)},$y=(e,t)=>{let n,r;for(;;){if(e.lookahead<Ir){if(Ys(e),e.lookahead<Ir&&t===ra)return Yt;if(e.lookahead===0)break}if(n=0,e.lookahead>=ye&&(e.ins_h=oa(e,e.ins_h,e.window[e.strstart+ye-1]),n=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart),n!==0&&e.strstart-n<=e.w_size-Ir&&(e.match_length=O5(e,n)),e.match_length>=ye)if(r=na(e,e.strstart-e.match_start,e.match_length-ye),e.lookahead-=e.match_length,e.match_length<=e.max_lazy_match&&e.lookahead>=ye){e.match_length--;do e.strstart++,e.ins_h=oa(e,e.ins_h,e.window[e.strstart+ye-1]),n=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart;while(--e.match_length!==0);e.strstart++}else e.strstart+=e.match_length,e.match_length=0,e.ins_h=e.window[e.strstart],e.ins_h=oa(e,e.ins_h,e.window[e.strstart+1]);else r=na(e,0,e.window[e.strstart]),e.lookahead--,e.strstart++;if(r&&(yn(e,!1),e.strm.avail_out===0))return Yt}return e.insert=e.strstart<ye-1?e.strstart:ye-1,t===Bn?(yn(e,!0),e.strm.avail_out===0?Ro:Ws):e.sym_next&&(yn(e,!1),e.strm.avail_out===0)?Yt:qs},Zs=(e,t)=>{let n,r,i;for(;;){if(e.lookahead<Ir){if(Ys(e),e.lookahead<Ir&&t===ra)return Yt;if(e.lookahead===0)break}if(n=0,e.lookahead>=ye&&(e.ins_h=oa(e,e.ins_h,e.window[e.strstart+ye-1]),n=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart),e.prev_length=e.match_length,e.prev_match=e.match_start,e.match_length=ye-1,n!==0&&e.prev_length<e.max_lazy_match&&e.strstart-n<=e.w_size-Ir&&(e.match_length=O5(e,n),e.match_length<=5&&(e.strategy===qZ||e.match_length===ye&&e.strstart-e.match_start>4096)&&(e.match_length=ye-1)),e.prev_length>=ye&&e.match_length<=e.prev_length){i=e.strstart+e.lookahead-ye,r=na(e,e.strstart-1-e.prev_match,e.prev_length-ye),e.lookahead-=e.prev_length-1,e.prev_length-=2;do++e.strstart<=i&&(e.ins_h=oa(e,e.ins_h,e.window[e.strstart+ye-1]),n=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart);while(--e.prev_length!==0);if(e.match_available=0,e.match_length=ye-1,e.strstart++,r&&(yn(e,!1),e.strm.avail_out===0))return Yt}else if(e.match_available){if(r=na(e,0,e.window[e.strstart-1]),r&&yn(e,!1),e.strstart++,e.lookahead--,e.strm.avail_out===0)return Yt}else e.match_available=1,e.strstart++,e.lookahead--}return e.match_available&&(r=na(e,0,e.window[e.strstart-1]),e.match_available=0),e.insert=e.strstart<ye-1?e.strstart:ye-1,t===Bn?(yn(e,!0),e.strm.avail_out===0?Ro:Ws):e.sym_next&&(yn(e,!1),e.strm.avail_out===0)?Yt:qs},cQ=(e,t)=>{let n,r,i,a;const o=e.window;for(;;){if(e.lookahead<=ia){if(Ys(e),e.lookahead<=ia&&t===ra)return Yt;if(e.lookahead===0)break}if(e.match_length=0,e.lookahead>=ye&&e.strstart>0&&(i=e.strstart-1,r=o[i],r===o[++i]&&r===o[++i]&&r===o[++i])){a=e.strstart+ia;do;while(r===o[++i]&&r===o[++i]&&r===o[++i]&&r===o[++i]&&r===o[++i]&&r===o[++i]&&r===o[++i]&&r===o[++i]&&i<a);e.match_length=ia-(a-i),e.match_length>e.lookahead&&(e.match_length=e.lookahead)}if(e.match_length>=ye?(n=na(e,1,e.match_length-ye),e.lookahead-=e.match_length,e.strstart+=e.match_length,e.match_length=0):(n=na(e,0,e.window[e.strstart]),e.lookahead--,e.strstart++),n&&(yn(e,!1),e.strm.avail_out===0))return Yt}return e.insert=0,t===Bn?(yn(e,!0),e.strm.avail_out===0?Ro:Ws):e.sym_next&&(yn(e,!1),e.strm.avail_out===0)?Yt:qs},lQ=(e,t)=>{let n;for(;;){if(e.lookahead===0&&(Ys(e),e.lookahead===0)){if(t===ra)return Yt;break}if(e.match_length=0,n=na(e,0,e.window[e.strstart]),e.lookahead--,e.strstart++,n&&(yn(e,!1),e.strm.avail_out===0))return Yt}return e.insert=0,t===Bn?(yn(e,!0),e.strm.avail_out===0?Ro:Ws):e.sym_next&&(yn(e,!1),e.strm.avail_out===0)?Yt:qs};function Rr(e,t,n,r,i){this.good_length=e,this.max_lazy=t,this.nice_length=n,this.max_chain=r,this.func=i}const $u=[new Rr(0,0,0,0,L5),new Rr(4,4,8,4,$y),new Rr(4,5,16,8,$y),new Rr(4,6,32,32,$y),new Rr(4,4,16,16,Zs),new Rr(8,16,32,32,Zs),new Rr(8,16,128,128,Zs),new Rr(8,32,128,256,Zs),new Rr(32,128,258,1024,Zs),new Rr(32,258,258,4096,Zs)],uQ=e=>{e.window_size=2*e.w_size,aa(e.head),e.max_lazy_match=$u[e.level].max_lazy,e.good_match=$u[e.level].good_length,e.nice_match=$u[e.level].nice_length,e.max_chain_length=$u[e.level].max_chain,e.strstart=0,e.block_start=0,e.lookahead=0,e.insert=0,e.match_length=e.prev_length=ye-1,e.match_available=0,e.ins_h=0};function fQ(){this.strm=null,this.status=0,this.pending_buf=null,this.pending_buf_size=0,this.pending_out=0,this.pending=0,this.wrap=0,this.gzhead=null,this.gzindex=0,this.method=k0,this.last_flush=-1,this.w_size=0,this.w_bits=0,this.w_mask=0,this.window=null,this.window_size=0,this.prev=null,this.head=null,this.ins_h=0,this.hash_size=0,this.hash_bits=0,this.hash_mask=0,this.hash_shift=0,this.block_start=0,this.match_length=0,this.prev_match=0,this.match_available=0,this.strstart=0,this.match_start=0,this.lookahead=0,this.prev_length=0,this.max_chain_length=0,this.max_lazy_match=0,this.level=0,this.strategy=0,this.good_match=0,this.nice_match=0,this.dyn_ltree=new Uint16Array(rQ*2),this.dyn_dtree=new Uint16Array((2*tQ+1)*2),this.bl_tree=new Uint16Array((2*nQ+1)*2),aa(this.dyn_ltree),aa(this.dyn_dtree),aa(this.bl_tree),this.l_desc=null,this.d_desc=null,this.bl_desc=null,this.bl_count=new Uint16Array(iQ+1),this.heap=new 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s=new fQ;return e.state=s,s.strm=e,s.status=js,s.wrap=o,s.gzhead=null,s.w_bits=r,s.w_size=1<<s.w_bits,s.w_mask=s.w_size-1,s.hash_bits=i+7,s.hash_size=1<<s.hash_bits,s.hash_mask=s.hash_size-1,s.hash_shift=~~((s.hash_bits+ye-1)/ye),s.window=new Uint8Array(s.w_size*2),s.head=new Uint16Array(s.hash_size),s.prev=new Uint16Array(s.w_size),s.lit_bufsize=1<<i+6,s.pending_buf_size=s.lit_bufsize*4,s.pending_buf=new Uint8Array(s.pending_buf_size),s.sym_buf=s.lit_bufsize,s.sym_end=(s.lit_bufsize-1)*3,s.level=t,s.strategy=a,s.method=n,z5(e)},dQ=(e,t)=>U5(e,t,k0,KZ,JZ,ZZ),pQ=(e,t)=>{if(Hu(e)||t>F5||t<0)return e?Do(e,Tr):Tr;const n=e.state;if(!e.output||e.avail_in!==0&&!e.input||n.status===zu&&t!==Bn)return Do(e,e.avail_out===0?Fy:Tr);const r=n.last_flush;if(n.last_flush=t,n.pending!==0){if(bn(e),e.avail_out===0)return n.last_flush=-1,Mt}else if(e.avail_in===0&&M5(t)<=M5(r)&&t!==Bn)return Do(e,Fy);if(n.status===zu&&e.avail_in!==0)return 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if(x&16){C=A&65535,x&=15,x&&(p<x&&(d+=M[r++]<<p,p+=8),C+=d&(1<<x)-1,d>>>=x,p-=x),p<15&&(d+=M[r++]<<p,p+=8,d+=M[r++]<<p,p+=8),A=b[d&w];n:for(;;){if(x=A>>>24,d>>>=x,p-=x,x=A>>>16&255,x&16){if(_=A&65535,x&=15,p<x&&(d+=M[r++]<<p,p+=8,p<x&&(d+=M[r++]<<p,p+=8)),_+=d&(1<<x)-1,_>c){t.msg="invalid distance too far back",O.mode=R0;break e}if(d>>>=x,p-=x,x=a-o,_>x){if(x=_-x,x>u&&O.sane){t.msg="invalid distance too far back",O.mode=R0;break e}if(I=0,D=h,f===0){if(I+=l-x,x<C){C-=x;do G[a++]=h[I++];while(--x);I=a-_,D=G}}else if(f<x){if(I+=l+f-x,x-=f,x<C){C-=x;do G[a++]=h[I++];while(--x);if(I=0,f<C){x=f,C-=x;do G[a++]=h[I++];while(--x);I=a-_,D=G}}}else if(I+=f-x,x<C){C-=x;do G[a++]=h[I++];while(--x);I=a-_,D=G}for(;C>2;)G[a++]=D[I++],G[a++]=D[I++],G[a++]=D[I++],C-=3;C&&(G[a++]=D[I++],C>1&&(G[a++]=D[I++]))}else{I=a-_;do G[a++]=G[I++],G[a++]=G[I++],G[a++]=G[I++],C-=3;while(C>2);C&&(G[a++]=G[I++],C>1&&(G[a++]=G[I++]))}}else if(x&64){t.msg="invalid distance code",O.mode=R0;break e}else{A=b[(A&65535)+(d&(1<<x)-1)];continue n}break}}else if(x&64)if(x&32){O.mode=HQ;break e}else{t.msg="invalid literal/length code",O.mode=R0;break e}else{A=g[(A&65535)+(d&(1<<x)-1)];continue t}break}}while(r<i&&a<s);C=p>>3,r-=C,p-=C<<3,d&=(1<<p)-1,t.next_in=r,t.next_out=a,t.avail_in=r<i?5+(i-r):5-(r-i),t.avail_out=a<s?257+(s-a):257-(a-s),O.hold=d,O.bits=p};const Qs=15,V5=852,j5=592,q5=0,Gy=1,W5=2,VQ=new Uint16Array([3,4,5,6,7,8,9,10,11,13,15,17,19,23,27,31,35,43,51,59,67,83,99,115,131,163,195,227,258,0,0]),jQ=new Uint8Array([16,16,16,16,16,16,16,16,17,17,17,17,18,18,18,18,19,19,19,19,20,20,20,20,21,21,21,21,16,72,78]),qQ=new Uint16Array([1,2,3,4,5,7,9,13,17,25,33,49,65,97,129,193,257,385,513,769,1025,1537,2049,3073,4097,6145,8193,12289,16385,24577,0,0]),WQ=new Uint8Array([16,16,16,16,17,17,18,18,19,19,20,20,21,21,22,22,23,23,24,24,25,25,26,26,27,27,28,28,29,29,64,64]);var qu=(e,t,n,r,i,a,o,s)=>{const c=s.bits;let l=0,u=0,f=0,h=0,d=0,p=0,g=0,b=0,y=0,w=0,A,x,C,_,I,D=null,M;const G=new Uint16Array(Qs+1),O=new Uint16Array(Qs+1);let ae=null,se,ve,Pe;for(l=0;l<=Qs;l++)G[l]=0;for(u=0;u<r;u++)G[t[n+u]]++;for(d=c,h=Qs;h>=1&&G[h]===0;h--);if(d>h&&(d=h),h===0)return i[a++]=1<<24|64<<16|0,i[a++]=1<<24|64<<16|0,s.bits=1,0;for(f=1;f<h&&G[f]===0;f++);for(d<f&&(d=f),b=1,l=1;l<=Qs;l++)if(b<<=1,b-=G[l],b<0)return-1;if(b>0&&(e===q5||h!==1))return-1;for(O[1]=0,l=1;l<Qs;l++)O[l+1]=O[l]+G[l];for(u=0;u<r;u++)t[n+u]!==0&&(o[O[t[n+u]]++]=u);if(e===q5?(D=ae=o,M=20):e===Gy?(D=VQ,ae=jQ,M=257):(D=qQ,ae=WQ,M=0),w=0,u=0,l=f,I=a,p=d,g=0,C=-1,y=1<<d,_=y-1,e===Gy&&y>V5||e===W5&&y>j5)return 1;for(;;){se=l-g,o[u]+1<M?(ve=0,Pe=o[u]):o[u]>=M?(ve=ae[o[u]-M],Pe=D[o[u]-M]):(ve=32+64,Pe=0),A=1<<l-g,x=1<<p,f=x;do x-=A,i[I+(w>>g)+x]=se<<24|ve<<16|Pe|0;while(x!==0);for(A=1<<l-1;w&A;)A>>=1;if(A!==0?(w&=A-1,w+=A):w=0,u++,--G[l]===0){if(l===h)break;l=t[n+o[u]]}if(l>d&&(w&_)!==C){for(g===0&&(g=d),I+=f,p=l-g,b=1<<p;p+g<h&&(b-=G[p+g],!(b<=0));)p++,b<<=1;if(y+=1<<p,e===Gy&&y>V5||e===W5&&y>j5)return 1;C=w&_,i[C]=d<<24|p<<16|I-a|0}}return w!==0&&(i[I+w]=l-g<<24|64<<16|0),s.bits=d,0};const YQ=0,Y5=1,Z5=2,{Z_FINISH:Q5,Z_BLOCK:ZQ,Z_TREES:D0,Z_OK:Bo,Z_STREAM_END:QQ,Z_NEED_DICT:XQ,Z_STREAM_ERROR:Fn,Z_DATA_ERROR:X5,Z_MEM_ERROR:K5,Z_BUF_ERROR:KQ,Z_DEFLATED:J5}=Nu,B0=16180,e8=16181,t8=16182,n8=16183,r8=16184,i8=16185,a8=16186,o8=16187,s8=16188,c8=16189,F0=16190,ni=16191,Vy=16192,l8=16193,jy=16194,u8=16195,f8=16196,h8=16197,d8=16198,P0=16199,M0=16200,p8=16201,g8=16202,m8=16203,b8=16204,y8=16205,qy=16206,v8=16207,w8=16208,Je=16209,x8=16210,A8=16211,JQ=852,eX=592,tX=15,E8=e=>(e>>>24&255)+(e>>>8&65280)+((e&65280)<<8)+((e&255)<<24);function nX(){this.strm=null,this.mode=0,this.last=!1,this.wrap=0,this.havedict=!1,this.flags=0,this.dmax=0,this.check=0,this.total=0,this.head=null,this.wbits=0,this.wsize=0,this.whave=0,this.wnext=0,this.window=null,this.hold=0,this.bits=0,this.length=0,this.offset=0,this.extra=0,this.lencode=null,this.distcode=null,this.lenbits=0,this.distbits=0,this.ncode=0,this.nlen=0,this.ndist=0,this.have=0,this.next=null,this.lens=new Uint16Array(320),this.work=new Uint16Array(288),this.lendyn=null,this.distdyn=null,this.sane=0,this.back=0,this.was=0}const Fo=e=>{if(!e)return 1;const t=e.state;return!t||t.strm!==e||t.mode<B0||t.mode>A8?1:0},S8=e=>{if(Fo(e))return Fn;const t=e.state;return e.total_in=e.total_out=t.total=0,e.msg="",t.wrap&&(e.adler=t.wrap&1),t.mode=B0,t.last=0,t.havedict=0,t.flags=-1,t.dmax=32768,t.head=null,t.hold=0,t.bits=0,t.lencode=t.lendyn=new Int32Array(JQ),t.distcode=t.distdyn=new Int32Array(eX),t.sane=1,t.back=-1,Bo},_8=e=>{if(Fo(e))return Fn;const t=e.state;return t.wsize=0,t.whave=0,t.wnext=0,S8(e)},C8=(e,t)=>{let n;if(Fo(e))return Fn;const r=e.state;return t<0?(n=0,t=-t):(n=(t>>4)+5,t<48&&(t&=15)),t&&(t<8||t>15)?Fn:(r.window!==null&&r.wbits!==t&&(r.window=null),r.wrap=n,r.wbits=t,_8(e))},k8=(e,t)=>{if(!e)return Fn;const n=new nX;e.state=n,n.strm=e,n.window=null,n.mode=B0;const r=C8(e,t);return r!==Bo&&(e.state=null),r},rX=e=>k8(e,tX);let T8=!0,Wy,Yy;const iX=e=>{if(T8){Wy=new Int32Array(512),Yy=new Int32Array(32);let t=0;for(;t<144;)e.lens[t++]=8;for(;t<256;)e.lens[t++]=9;for(;t<280;)e.lens[t++]=7;for(;t<288;)e.lens[t++]=8;for(qu(Y5,e.lens,0,288,Wy,0,e.work,{bits:9}),t=0;t<32;)e.lens[t++]=5;qu(Z5,e.lens,0,32,Yy,0,e.work,{bits:5}),T8=!1}e.lencode=Wy,e.lenbits=9,e.distcode=Yy,e.distbits=5},I8=(e,t,n,r)=>{let i;const a=e.state;return a.window===null&&(a.wsize=1<<a.wbits,a.wnext=0,a.whave=0,a.window=new Uint8Array(a.wsize)),r>=a.wsize?(a.window.set(t.subarray(n-a.wsize,n),0),a.wnext=0,a.whave=a.wsize):(i=a.wsize-a.wnext,i>r&&(i=r),a.window.set(t.subarray(n-r,n-r+i),a.wnext),r-=i,r?(a.window.set(t.subarray(n-r,n),0),a.wnext=r,a.whave=a.wsize):(a.wnext+=i,a.wnext===a.wsize&&(a.wnext=0),a.whave<a.wsize&&(a.whave+=i))),0},aX=(e,t)=>{let n,r,i,a,o,s,c,l,u,f,h,d,p,g,b=0,y,w,A,x,C,_,I,D;const M=new Uint8Array(4);let G,O;const ae=new Uint8Array([16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15]);if(Fo(e)||!e.output||!e.input&&e.avail_in!==0)return Fn;n=e.state,n.mode===ni&&(n.mode=Vy),o=e.next_out,i=e.output,c=e.avail_out,a=e.next_in,r=e.input,s=e.avail_in,l=n.hold,u=n.bits,f=s,h=c,D=Bo;e:for(;;)switch(n.mode){case B0:if(n.wrap===0){n.mode=Vy;break}for(;u<16;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(n.wrap&2&&l===35615){n.wbits===0&&(n.wbits=15),n.check=0,M[0]=l&255,M[1]=l>>>8&255,n.check=Tt(n.check,M,2,0),l=0,u=0,n.mode=e8;break}if(n.head&&(n.head.done=!1),!(n.wrap&1)||(((l&255)<<8)+(l>>8))%31){e.msg="incorrect header check",n.mode=Je;break}if((l&15)!==J5){e.msg="unknown compression method",n.mode=Je;break}if(l>>>=4,u-=4,I=(l&15)+8,n.wbits===0&&(n.wbits=I),I>15||I>n.wbits){e.msg="invalid window size",n.mode=Je;break}n.dmax=1<<n.wbits,n.flags=0,e.adler=n.check=1,n.mode=l&512?c8:ni,l=0,u=0;break;case e8:for(;u<16;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(n.flags=l,(n.flags&255)!==J5){e.msg="unknown compression method",n.mode=Je;break}if(n.flags&57344){e.msg="unknown header flags set",n.mode=Je;break}n.head&&(n.head.text=l>>8&1),n.flags&512&&n.wrap&4&&(M[0]=l&255,M[1]=l>>>8&255,n.check=Tt(n.check,M,2,0)),l=0,u=0,n.mode=t8;case t8:for(;u<32;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}n.head&&(n.head.time=l),n.flags&512&&n.wrap&4&&(M[0]=l&255,M[1]=l>>>8&255,M[2]=l>>>16&255,M[3]=l>>>24&255,n.check=Tt(n.check,M,4,0)),l=0,u=0,n.mode=n8;case n8:for(;u<16;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}n.head&&(n.head.xflags=l&255,n.head.os=l>>8),n.flags&512&&n.wrap&4&&(M[0]=l&255,M[1]=l>>>8&255,n.check=Tt(n.check,M,2,0)),l=0,u=0,n.mode=r8;case r8:if(n.flags&1024){for(;u<16;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}n.length=l,n.head&&(n.head.extra_len=l),n.flags&512&&n.wrap&4&&(M[0]=l&255,M[1]=l>>>8&255,n.check=Tt(n.check,M,2,0)),l=0,u=0}else n.head&&(n.head.extra=null);n.mode=i8;case i8:if(n.flags&1024&&(d=n.length,d>s&&(d=s),d&&(n.head&&(I=n.head.extra_len-n.length,n.head.extra||(n.head.extra=new Uint8Array(n.head.extra_len)),n.head.extra.set(r.subarray(a,a+d),I)),n.flags&512&&n.wrap&4&&(n.check=Tt(n.check,r,d,a)),s-=d,a+=d,n.length-=d),n.length))break e;n.length=0,n.mode=a8;case a8:if(n.flags&2048){if(s===0)break e;d=0;do I=r[a+d++],n.head&&I&&n.length<65536&&(n.head.name+=String.fromCharCode(I));while(I&&d<s);if(n.flags&512&&n.wrap&4&&(n.check=Tt(n.check,r,d,a)),s-=d,a+=d,I)break e}else n.head&&(n.head.name=null);n.length=0,n.mode=o8;case o8:if(n.flags&4096){if(s===0)break e;d=0;do I=r[a+d++],n.head&&I&&n.length<65536&&(n.head.comment+=String.fromCharCode(I));while(I&&d<s);if(n.flags&512&&n.wrap&4&&(n.check=Tt(n.check,r,d,a)),s-=d,a+=d,I)break e}else n.head&&(n.head.comment=null);n.mode=s8;case s8:if(n.flags&512){for(;u<16;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(n.wrap&4&&l!==(n.check&65535)){e.msg="header crc mismatch",n.mode=Je;break}l=0,u=0}n.head&&(n.head.hcrc=n.flags>>9&1,n.head.done=!0),e.adler=n.check=0,n.mode=ni;break;case c8:for(;u<32;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}e.adler=n.check=E8(l),l=0,u=0,n.mode=F0;case F0:if(n.havedict===0)return e.next_out=o,e.avail_out=c,e.next_in=a,e.avail_in=s,n.hold=l,n.bits=u,XQ;e.adler=n.check=1,n.mode=ni;case ni:if(t===ZQ||t===D0)break e;case Vy:if(n.last){l>>>=u&7,u-=u&7,n.mode=qy;break}for(;u<3;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}switch(n.last=l&1,l>>>=1,u-=1,l&3){case 0:n.mode=l8;break;case 1:if(iX(n),n.mode=P0,t===D0){l>>>=2,u-=2;break e}break;case 2:n.mode=f8;break;case 3:e.msg="invalid block type",n.mode=Je}l>>>=2,u-=2;break;case l8:for(l>>>=u&7,u-=u&7;u<32;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if((l&65535)!==(l>>>16^65535)){e.msg="invalid stored block lengths",n.mode=Je;break}if(n.length=l&65535,l=0,u=0,n.mode=jy,t===D0)break e;case jy:n.mode=u8;case u8:if(d=n.length,d){if(d>s&&(d=s),d>c&&(d=c),d===0)break e;i.set(r.subarray(a,a+d),o),s-=d,a+=d,c-=d,o+=d,n.length-=d;break}n.mode=ni;break;case f8:for(;u<14;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(n.nlen=(l&31)+257,l>>>=5,u-=5,n.ndist=(l&31)+1,l>>>=5,u-=5,n.ncode=(l&15)+4,l>>>=4,u-=4,n.nlen>286||n.ndist>30){e.msg="too many length or distance symbols",n.mode=Je;break}n.have=0,n.mode=h8;case h8:for(;n.have<n.ncode;){for(;u<3;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}n.lens[ae[n.have++]]=l&7,l>>>=3,u-=3}for(;n.have<19;)n.lens[ae[n.have++]]=0;if(n.lencode=n.lendyn,n.lenbits=7,G={bits:n.lenbits},D=qu(YQ,n.lens,0,19,n.lencode,0,n.work,G),n.lenbits=G.bits,D){e.msg="invalid code lengths set",n.mode=Je;break}n.have=0,n.mode=d8;case d8:for(;n.have<n.nlen+n.ndist;){for(;b=n.lencode[l&(1<<n.lenbits)-1],y=b>>>24,w=b>>>16&255,A=b&65535,!(y<=u);){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(A<16)l>>>=y,u-=y,n.lens[n.have++]=A;else{if(A===16){for(O=y+2;u<O;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(l>>>=y,u-=y,n.have===0){e.msg="invalid bit length repeat",n.mode=Je;break}I=n.lens[n.have-1],d=3+(l&3),l>>>=2,u-=2}else if(A===17){for(O=y+3;u<O;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}l>>>=y,u-=y,I=0,d=3+(l&7),l>>>=3,u-=3}else{for(O=y+7;u<O;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}l>>>=y,u-=y,I=0,d=11+(l&127),l>>>=7,u-=7}if(n.have+d>n.nlen+n.ndist){e.msg="invalid bit length repeat",n.mode=Je;break}for(;d--;)n.lens[n.have++]=I}}if(n.mode===Je)break;if(n.lens[256]===0){e.msg="invalid code -- missing end-of-block",n.mode=Je;break}if(n.lenbits=9,G={bits:n.lenbits},D=qu(Y5,n.lens,0,n.nlen,n.lencode,0,n.work,G),n.lenbits=G.bits,D){e.msg="invalid literal/lengths set",n.mode=Je;break}if(n.distbits=6,n.distcode=n.distdyn,G={bits:n.distbits},D=qu(Z5,n.lens,n.nlen,n.ndist,n.distcode,0,n.work,G),n.distbits=G.bits,D){e.msg="invalid distances set",n.mode=Je;break}if(n.mode=P0,t===D0)break e;case P0:n.mode=M0;case M0:if(s>=6&&c>=258){e.next_out=o,e.avail_out=c,e.next_in=a,e.avail_in=s,n.hold=l,n.bits=u,GQ(e,h),o=e.next_out,i=e.output,c=e.avail_out,a=e.next_in,r=e.input,s=e.avail_in,l=n.hold,u=n.bits,n.mode===ni&&(n.back=-1);break}for(n.back=0;b=n.lencode[l&(1<<n.lenbits)-1],y=b>>>24,w=b>>>16&255,A=b&65535,!(y<=u);){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(w&&!(w&240)){for(x=y,C=w,_=A;b=n.lencode[_+((l&(1<<x+C)-1)>>x)],y=b>>>24,w=b>>>16&255,A=b&65535,!(x+y<=u);){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}l>>>=x,u-=x,n.back+=x}if(l>>>=y,u-=y,n.back+=y,n.length=A,w===0){n.mode=y8;break}if(w&32){n.back=-1,n.mode=ni;break}if(w&64){e.msg="invalid literal/length code",n.mode=Je;break}n.extra=w&15,n.mode=p8;case p8:if(n.extra){for(O=n.extra;u<O;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}n.length+=l&(1<<n.extra)-1,l>>>=n.extra,u-=n.extra,n.back+=n.extra}n.was=n.length,n.mode=g8;case g8:for(;b=n.distcode[l&(1<<n.distbits)-1],y=b>>>24,w=b>>>16&255,A=b&65535,!(y<=u);){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(!(w&240)){for(x=y,C=w,_=A;b=n.distcode[_+((l&(1<<x+C)-1)>>x)],y=b>>>24,w=b>>>16&255,A=b&65535,!(x+y<=u);){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}l>>>=x,u-=x,n.back+=x}if(l>>>=y,u-=y,n.back+=y,w&64){e.msg="invalid distance code",n.mode=Je;break}n.offset=A,n.extra=w&15,n.mode=m8;case 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3274
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n=t.dyn_tree,r=t.max_code,i=t.stat_desc.static_tree,a=t.stat_desc.has_stree,o=t.stat_desc.extra_bits,s=t.stat_desc.extra_base,c=t.stat_desc.max_length,l,u,f,h,d,p,g=0;for(h=0;h<=go;h++)e.bl_count[h]=0;for(n[e.heap[e.heap_max]*2+1]=0,l=e.heap_max+1;l<v6;l++)u=e.heap[l],h=n[n[u*2+1]*2+1]+1,h>c&&(h=c,g++),n[u*2+1]=h,!(u>r)&&(e.bl_count[h]++,d=0,u>=s&&(d=o[u-s]),p=n[u*2],e.opt_len+=p*(h+d),a&&(e.static_len+=p*(i[u*2+1]+d)));if(g!==0){do{for(h=c-1;e.bl_count[h]===0;)h--;e.bl_count[h]--,e.bl_count[h+1]+=2,e.bl_count[c]--,g-=2}while(g>0);for(h=c;h!==0;h--)for(u=e.bl_count[h];u!==0;)f=e.heap[--l],!(f>r)&&(n[f*2+1]!==h&&(e.opt_len+=(h-n[f*2+1])*n[f*2],n[f*2+1]=h),u--)}}function I6(e,t,n){var r=new Array(go+1),i=0,a,o;for(a=1;a<=go;a++)r[a]=i=i+n[a-1]<<1;for(o=0;o<=t;o++){var s=e[o*2+1];s!==0&&(e[o*2]=T6(r[s]++,s))}}function nW(){var e,t,n,r,i,a=new Array(go+1);for(n=0,r=0;r<zb-1;r++)for(Vb[r]=n,e=0;e<1<<Gb[r];e++)yu[n++]=r;for(yu[n-1]=r,i=0,r=0;r<16;r++)for(Kd[r]=i,e=0;e<1<<Xd[r];e++)bu[i++]=r;for(i>>=7;r<Bs;r++)for(Kd[r]=i<<7,e=0;e<1<<Xd[r]-7;e++)bu[256+i++]=r;for(t=0;t<=go;t++)a[t]=0;for(e=0;e<=143;)Jr[e*2+1]=8,e++,a[8]++;for(;e<=255;)Jr[e*2+1]=9,e++,a[9]++;for(;e<=279;)Jr[e*2+1]=7,e++,a[7]++;for(;e<=287;)Jr[e*2+1]=8,e++,a[8]++;for(I6(Jr,gu+1,a),e=0;e<Bs;e++)mu[e*2+1]=5,mu[e*2]=T6(e,5);S6=new jb(Jr,Gb,pu+1,gu,go),_6=new jb(mu,Xd,0,Bs,go),C6=new jb(new Array(0),Kq,0,Ub,Xq)}function R6(e){var t;for(t=0;t<gu;t++)e.dyn_ltree[t*2]=0;for(t=0;t<Bs;t++)e.dyn_dtree[t*2]=0;for(t=0;t<Ub;t++)e.bl_tree[t*2]=0;e.dyn_ltree[Hb*2]=1,e.opt_len=e.static_len=0,e.last_lit=e.matches=0}function D6(e){e.bi_valid>8?vu(e,e.bi_buf):e.bi_valid>0&&(e.pending_buf[e.pending++]=e.bi_buf),e.bi_buf=0,e.bi_valid=0}function rW(e,t,n,r){D6(e),r&&(vu(e,n),vu(e,~n)),Vq.arraySet(e.pending_buf,e.window,t,n,e.pending),e.pending+=n}function B6(e,t,n,r){var i=t*2,a=n*2;return e[i]<e[a]||e[i]===e[a]&&r[t]<=r[n]}function Wb(e,t,n){for(var r=e.heap[n],i=n<<1;i<=e.heap_len&&(i<e.heap_len&&B6(t,e.heap[i+1],e.heap[i],e.depth)&&i++,!B6(t,r,e.heap[i],e.depth));)e.heap[n]=e.heap[i],n=i,i<<=1;e.heap[n]=r}function F6(e,t,n){var r,i,a=0,o,s;if(e.last_lit!==0)do r=e.pending_buf[e.d_buf+a*2]<<8|e.pending_buf[e.d_buf+a*2+1],i=e.pending_buf[e.l_buf+a],a++,r===0?Er(e,i,t):(o=yu[i],Er(e,o+pu+1,t),s=Gb[o],s!==0&&(i-=Vb[o],an(e,i,s)),r--,o=k6(r),Er(e,o,n),s=Xd[o],s!==0&&(r-=Kd[o],an(e,r,s)));while(a<e.last_lit);Er(e,Hb,t)}function Yb(e,t){var n=t.dyn_tree,r=t.stat_desc.static_tree,i=t.stat_desc.has_stree,a=t.stat_desc.elems,o,s,c=-1,l;for(e.heap_len=0,e.heap_max=v6,o=0;o<a;o++)n[o*2]!==0?(e.heap[++e.heap_len]=c=o,e.depth[o]=0):n[o*2+1]=0;for(;e.heap_len<2;)l=e.heap[++e.heap_len]=c<2?++c:0,n[l*2]=1,e.depth[l]=0,e.opt_len--,i&&(e.static_len-=r[l*2+1]);for(t.max_code=c,o=e.heap_len>>1;o>=1;o--)Wb(e,n,o);l=a;do o=e.heap[1],e.heap[1]=e.heap[e.heap_len--],Wb(e,n,1),s=e.heap[1],e.heap[--e.heap_max]=o,e.heap[--e.heap_max]=s,n[l*2]=n[o*2]+n[s*2],e.depth[l]=(e.depth[o]>=e.depth[s]?e.depth[o]:e.depth[s])+1,n[o*2+1]=n[s*2+1]=l,e.heap[1]=l++,Wb(e,n,1);while(e.heap_len>=2);e.heap[--e.heap_max]=e.heap[1],tW(e,t),I6(n,c,e.bl_count)}function P6(e,t,n){var r,i=-1,a,o=t[0*2+1],s=0,c=7,l=4;for(o===0&&(c=138,l=3),t[(n+1)*2+1]=65535,r=0;r<=n;r++)a=o,o=t[(r+1)*2+1],!(++s<c&&a===o)&&(s<l?e.bl_tree[a*2]+=s:a!==0?(a!==i&&e.bl_tree[a*2]++,e.bl_tree[w6*2]++):s<=10?e.bl_tree[x6*2]++:e.bl_tree[A6*2]++,s=0,i=a,o===0?(c=138,l=3):a===o?(c=6,l=3):(c=7,l=4))}function M6(e,t,n){var r,i=-1,a,o=t[0*2+1],s=0,c=7,l=4;for(o===0&&(c=138,l=3),r=0;r<=n;r++)if(a=o,o=t[(r+1)*2+1],!(++s<c&&a===o)){if(s<l)do Er(e,a,e.bl_tree);while(--s!==0);else a!==0?(a!==i&&(Er(e,a,e.bl_tree),s--),Er(e,w6,e.bl_tree),an(e,s-3,2)):s<=10?(Er(e,x6,e.bl_tree),an(e,s-3,3)):(Er(e,A6,e.bl_tree),an(e,s-11,7));s=0,i=a,o===0?(c=138,l=3):a===o?(c=6,l=3):(c=7,l=4)}}function iW(e){var t;for(P6(e,e.dyn_ltree,e.l_desc.max_code),P6(e,e.dyn_dtree,e.d_desc.max_code),Yb(e,e.bl_desc),t=Ub-1;t>=3&&e.bl_tree[E6[t]*2+1]===0;t--);return e.opt_len+=3*(t+1)+5+5+4,t}function aW(e,t,n,r){var i;for(an(e,t-257,5),an(e,n-1,5),an(e,r-4,4),i=0;i<r;i++)an(e,e.bl_tree[E6[i]*2+1],3);M6(e,e.dyn_ltree,t-1),M6(e,e.dyn_dtree,n-1)}function oW(e){var t=4093624447,n;for(n=0;n<=31;n++,t>>>=1)if(t&1&&e.dyn_ltree[n*2]!==0)return m6;if(e.dyn_ltree[9*2]!==0||e.dyn_ltree[10*2]!==0||e.dyn_ltree[13*2]!==0)return b6;for(n=32;n<pu;n++)if(e.dyn_ltree[n*2]!==0)return b6;return m6}var O6=!1;function sW(e){O6||(nW(),O6=!0),e.l_desc=new qb(e.dyn_ltree,S6),e.d_desc=new qb(e.dyn_dtree,_6),e.bl_desc=new qb(e.bl_tree,C6),e.bi_buf=0,e.bi_valid=0,R6(e)}function L6(e,t,n,r){an(e,(Wq<<1)+(r?1:0),3),rW(e,t,n,!0)}function cW(e){an(e,y6<<1,3),Er(e,Hb,Jr),eW(e)}function lW(e,t,n,r){var i,a,o=0;e.level>0?(e.strm.data_type===qq&&(e.strm.data_type=oW(e)),Yb(e,e.l_desc),Yb(e,e.d_desc),o=iW(e),i=e.opt_len+3+7>>>3,a=e.static_len+3+7>>>3,a<=i&&(i=a)):i=a=n+5,n+4<=i&&t!==-1?L6(e,t,n,r):e.strategy===jq||a===i?(an(e,(y6<<1)+(r?1:0),3),F6(e,Jr,mu)):(an(e,(Yq<<1)+(r?1:0),3),aW(e,e.l_desc.max_code+1,e.d_desc.max_code+1,o+1),F6(e,e.dyn_ltree,e.dyn_dtree)),R6(e),r&&D6(e)}function uW(e,t,n){return e.pending_buf[e.d_buf+e.last_lit*2]=t>>>8&255,e.pending_buf[e.d_buf+e.last_lit*2+1]=t&255,e.pending_buf[e.l_buf+e.last_lit]=n&255,e.last_lit++,t===0?e.dyn_ltree[n*2]++:(e.matches++,t--,e.dyn_ltree[(yu[n]+pu+1)*2]++,e.dyn_dtree[k6(t)*2]++),e.last_lit===e.lit_bufsize-1}Rs._tr_init=sW,Rs._tr_stored_block=L6,Rs._tr_flush_block=lW,Rs._tr_tally=uW,Rs._tr_align=cW;function fW(e,t,n,r){for(var i=e&65535|0,a=e>>>16&65535|0,o=0;n!==0;){o=n>2e3?2e3:n,n-=o;do i=i+t[r++]|0,a=a+i|0;while(--o);i%=65521,a%=65521}return i|a<<16|0}var N6=fW;function hW(){for(var e,t=[],n=0;n<256;n++){e=n;for(var r=0;r<8;r++)e=e&1?3988292384^e>>>1:e>>>1;t[n]=e}return t}var dW=hW();function pW(e,t,n,r){var i=dW,a=r+n;e^=-1;for(var o=r;o<a;o++)e=e>>>8^i[(e^t[o])&255];return e^-1}var z6=pW,Zb={2:"need dictionary",1:"stream end",0:"","-1":"file error","-2":"stream error","-3":"data error","-4":"insufficient memory","-5":"buffer error","-6":"incompatible version"},Wt=Kr,Cn=Rs,U6=N6,Wi=z6,gW=Zb,mo=0,mW=1,bW=3,Yi=4,$6=5,Sr=0,H6=1,kn=-2,yW=-3,Qb=-5,vW=-1,wW=1,Jd=2,xW=3,AW=4,EW=0,SW=2,e0=8,_W=9,CW=15,kW=8,TW=29,IW=256,Xb=IW+1+TW,RW=30,DW=19,BW=2*Xb+1,FW=15,be=3,Zi=258,er=Zi+be+1,PW=32,t0=42,Kb=69,n0=73,r0=91,i0=103,bo=113,wu=666,yt=1,xu=2,yo=3,Fs=4,MW=3;function Qi(e,t){return e.msg=gW[t],t}function G6(e){return(e<<1)-(e>4?9:0)}function Xi(e){for(var t=e.length;--t>=0;)e[t]=0}function Ki(e){var t=e.state,n=t.pending;n>e.avail_out&&(n=e.avail_out),n!==0&&(Wt.arraySet(e.output,t.pending_buf,t.pending_out,n,e.next_out),e.next_out+=n,t.pending_out+=n,e.total_out+=n,e.avail_out-=n,t.pending-=n,t.pending===0&&(t.pending_out=0))}function Pt(e,t){Cn._tr_flush_block(e,e.block_start>=0?e.block_start:-1,e.strstart-e.block_start,t),e.block_start=e.strstart,Ki(e.strm)}function Se(e,t){e.pending_buf[e.pending++]=t}function Au(e,t){e.pending_buf[e.pending++]=t>>>8&255,e.pending_buf[e.pending++]=t&255}function OW(e,t,n,r){var i=e.avail_in;return i>r&&(i=r),i===0?0:(e.avail_in-=i,Wt.arraySet(t,e.input,e.next_in,i,n),e.state.wrap===1?e.adler=U6(e.adler,t,i,n):e.state.wrap===2&&(e.adler=Wi(e.adler,t,i,n)),e.next_in+=i,e.total_in+=i,i)}function V6(e,t){var n=e.max_chain_length,r=e.strstart,i,a,o=e.prev_length,s=e.nice_match,c=e.strstart>e.w_size-er?e.strstart-(e.w_size-er):0,l=e.window,u=e.w_mask,f=e.prev,h=e.strstart+Zi,d=l[r+o-1],p=l[r+o];e.prev_length>=e.good_match&&(n>>=2),s>e.lookahead&&(s=e.lookahead);do if(i=t,!(l[i+o]!==p||l[i+o-1]!==d||l[i]!==l[r]||l[++i]!==l[r+1])){r+=2,i++;do;while(l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&r<h);if(a=Zi-(h-r),r=h-Zi,a>o){if(e.match_start=t,o=a,a>=s)break;d=l[r+o-1],p=l[r+o]}}while((t=f[t&u])>c&&--n!==0);return o<=e.lookahead?o:e.lookahead}function vo(e){var t=e.w_size,n,r,i,a,o;do{if(a=e.window_size-e.lookahead-e.strstart,e.strstart>=t+(t-er)){Wt.arraySet(e.window,e.window,t,t,0),e.match_start-=t,e.strstart-=t,e.block_start-=t,r=e.hash_size,n=r;do i=e.head[--n],e.head[n]=i>=t?i-t:0;while(--r);r=t,n=r;do i=e.prev[--n],e.prev[n]=i>=t?i-t:0;while(--r);a+=t}if(e.strm.avail_in===0)break;if(r=OW(e.strm,e.window,e.strstart+e.lookahead,a),e.lookahead+=r,e.lookahead+e.insert>=be)for(o=e.strstart-e.insert,e.ins_h=e.window[o],e.ins_h=(e.ins_h<<e.hash_shift^e.window[o+1])&e.hash_mask;e.insert&&(e.ins_h=(e.ins_h<<e.hash_shift^e.window[o+be-1])&e.hash_mask,e.prev[o&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=o,o++,e.insert--,!(e.lookahead+e.insert<be)););}while(e.lookahead<er&&e.strm.avail_in!==0)}function LW(e,t){var n=65535;for(n>e.pending_buf_size-5&&(n=e.pending_buf_size-5);;){if(e.lookahead<=1){if(vo(e),e.lookahead===0&&t===mo)return yt;if(e.lookahead===0)break}e.strstart+=e.lookahead,e.lookahead=0;var r=e.block_start+n;if((e.strstart===0||e.strstart>=r)&&(e.lookahead=e.strstart-r,e.strstart=r,Pt(e,!1),e.strm.avail_out===0)||e.strstart-e.block_start>=e.w_size-er&&(Pt(e,!1),e.strm.avail_out===0))return yt}return e.insert=0,t===Yi?(Pt(e,!0),e.strm.avail_out===0?yo:Fs):(e.strstart>e.block_start&&(Pt(e,!1),e.strm.avail_out===0),yt)}function Jb(e,t){for(var n,r;;){if(e.lookahead<er){if(vo(e),e.lookahead<er&&t===mo)return yt;if(e.lookahead===0)break}if(n=0,e.lookahead>=be&&(e.ins_h=(e.ins_h<<e.hash_shift^e.window[e.strstart+be-1])&e.hash_mask,n=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart),n!==0&&e.strstart-n<=e.w_size-er&&(e.match_length=V6(e,n)),e.match_length>=be)if(r=Cn._tr_tally(e,e.strstart-e.match_start,e.match_length-be),e.lookahead-=e.match_length,e.match_length<=e.max_lazy_match&&e.lookahead>=be){e.match_length--;do e.strstart++,e.ins_h=(e.ins_h<<e.hash_shift^e.window[e.strstart+be-1])&e.hash_mask,n=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart;while(--e.match_length!==0);e.strstart++}else e.strstart+=e.match_length,e.match_length=0,e.ins_h=e.window[e.strstart],e.ins_h=(e.ins_h<<e.hash_shift^e.window[e.strstart+1])&e.hash_mask;else r=Cn._tr_tally(e,0,e.window[e.strstart]),e.lookahead--,e.strstart++;if(r&&(Pt(e,!1),e.strm.avail_out===0))return yt}return e.insert=e.strstart<be-1?e.strstart:be-1,t===Yi?(Pt(e,!0),e.strm.avail_out===0?yo:Fs):e.last_lit&&(Pt(e,!1),e.strm.avail_out===0)?yt:xu}function Ps(e,t){for(var n,r,i;;){if(e.lookahead<er){if(vo(e),e.lookahead<er&&t===mo)return yt;if(e.lookahead===0)break}if(n=0,e.lookahead>=be&&(e.ins_h=(e.ins_h<<e.hash_shift^e.window[e.strstart+be-1])&e.hash_mask,n=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart),e.prev_length=e.match_length,e.prev_match=e.match_start,e.match_length=be-1,n!==0&&e.prev_length<e.max_lazy_match&&e.strstart-n<=e.w_size-er&&(e.match_length=V6(e,n),e.match_length<=5&&(e.strategy===wW||e.match_length===be&&e.strstart-e.match_start>4096)&&(e.match_length=be-1)),e.prev_length>=be&&e.match_length<=e.prev_length){i=e.strstart+e.lookahead-be,r=Cn._tr_tally(e,e.strstart-1-e.prev_match,e.prev_length-be),e.lookahead-=e.prev_length-1,e.prev_length-=2;do++e.strstart<=i&&(e.ins_h=(e.ins_h<<e.hash_shift^e.window[e.strstart+be-1])&e.hash_mask,n=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart);while(--e.prev_length!==0);if(e.match_available=0,e.match_length=be-1,e.strstart++,r&&(Pt(e,!1),e.strm.avail_out===0))return yt}else if(e.match_available){if(r=Cn._tr_tally(e,0,e.window[e.strstart-1]),r&&Pt(e,!1),e.strstart++,e.lookahead--,e.strm.avail_out===0)return yt}else e.match_available=1,e.strstart++,e.lookahead--}return e.match_available&&(r=Cn._tr_tally(e,0,e.window[e.strstart-1]),e.match_available=0),e.insert=e.strstart<be-1?e.strstart:be-1,t===Yi?(Pt(e,!0),e.strm.avail_out===0?yo:Fs):e.last_lit&&(Pt(e,!1),e.strm.avail_out===0)?yt:xu}function NW(e,t){for(var n,r,i,a,o=e.window;;){if(e.lookahead<=Zi){if(vo(e),e.lookahead<=Zi&&t===mo)return yt;if(e.lookahead===0)break}if(e.match_length=0,e.lookahead>=be&&e.strstart>0&&(i=e.strstart-1,r=o[i],r===o[++i]&&r===o[++i]&&r===o[++i])){a=e.strstart+Zi;do;while(r===o[++i]&&r===o[++i]&&r===o[++i]&&r===o[++i]&&r===o[++i]&&r===o[++i]&&r===o[++i]&&r===o[++i]&&i<a);e.match_length=Zi-(a-i),e.match_length>e.lookahead&&(e.match_length=e.lookahead)}if(e.match_length>=be?(n=Cn._tr_tally(e,1,e.match_length-be),e.lookahead-=e.match_length,e.strstart+=e.match_length,e.match_length=0):(n=Cn._tr_tally(e,0,e.window[e.strstart]),e.lookahead--,e.strstart++),n&&(Pt(e,!1),e.strm.avail_out===0))return yt}return e.insert=0,t===Yi?(Pt(e,!0),e.strm.avail_out===0?yo:Fs):e.last_lit&&(Pt(e,!1),e.strm.avail_out===0)?yt:xu}function zW(e,t){for(var n;;){if(e.lookahead===0&&(vo(e),e.lookahead===0)){if(t===mo)return yt;break}if(e.match_length=0,n=Cn._tr_tally(e,0,e.window[e.strstart]),e.lookahead--,e.strstart++,n&&(Pt(e,!1),e.strm.avail_out===0))return yt}return e.insert=0,t===Yi?(Pt(e,!0),e.strm.avail_out===0?yo:Fs):e.last_lit&&(Pt(e,!1),e.strm.avail_out===0)?yt:xu}function _r(e,t,n,r,i){this.good_length=e,this.max_lazy=t,this.nice_length=n,this.max_chain=r,this.func=i}var Ms;Ms=[new _r(0,0,0,0,LW),new _r(4,4,8,4,Jb),new _r(4,5,16,8,Jb),new _r(4,6,32,32,Jb),new _r(4,4,16,16,Ps),new _r(8,16,32,32,Ps),new _r(8,16,128,128,Ps),new _r(8,32,128,256,Ps),new _r(32,128,258,1024,Ps),new _r(32,258,258,4096,Ps)];function UW(e){e.window_size=2*e.w_size,Xi(e.head),e.max_lazy_match=Ms[e.level].max_lazy,e.good_match=Ms[e.level].good_length,e.nice_match=Ms[e.level].nice_length,e.max_chain_length=Ms[e.level].max_chain,e.strstart=0,e.block_start=0,e.lookahead=0,e.insert=0,e.match_length=e.prev_length=be-1,e.match_available=0,e.ins_h=0}function $W(){this.strm=null,this.status=0,this.pending_buf=null,this.pending_buf_size=0,this.pending_out=0,this.pending=0,this.wrap=0,this.gzhead=null,this.gzindex=0,this.method=e0,this.last_flush=-1,this.w_size=0,this.w_bits=0,this.w_mask=0,this.window=null,this.window_size=0,this.prev=null,this.head=null,this.ins_h=0,this.hash_size=0,this.hash_bits=0,this.hash_mask=0,this.hash_shift=0,this.block_start=0,this.match_length=0,this.prev_match=0,this.match_available=0,this.strstart=0,this.match_start=0,this.lookahead=0,this.prev_length=0,this.max_chain_length=0,this.max_lazy_match=0,this.level=0,this.strategy=0,this.good_match=0,this.nice_match=0,this.dyn_ltree=new Wt.Buf16(BW*2),this.dyn_dtree=new Wt.Buf16((2*RW+1)*2),this.bl_tree=new Wt.Buf16((2*DW+1)*2),Xi(this.dyn_ltree),Xi(this.dyn_dtree),Xi(this.bl_tree),this.l_desc=null,this.d_desc=null,this.bl_desc=null,this.bl_count=new Wt.Buf16(FW+1),this.heap=new Wt.Buf16(2*Xb+1),Xi(this.heap),this.heap_len=0,this.heap_max=0,this.depth=new Wt.Buf16(2*Xb+1),Xi(this.depth),this.l_buf=0,this.lit_bufsize=0,this.last_lit=0,this.d_buf=0,this.opt_len=0,this.static_len=0,this.matches=0,this.insert=0,this.bi_buf=0,this.bi_valid=0}function j6(e){var t;return!e||!e.state?Qi(e,kn):(e.total_in=e.total_out=0,e.data_type=SW,t=e.state,t.pending=0,t.pending_out=0,t.wrap<0&&(t.wrap=-t.wrap),t.status=t.wrap?t0:bo,e.adler=t.wrap===2?0:1,t.last_flush=mo,Cn._tr_init(t),Sr)}function q6(e){var t=j6(e);return t===Sr&&UW(e.state),t}function HW(e,t){return!e||!e.state||e.state.wrap!==2?kn:(e.state.gzhead=t,Sr)}function W6(e,t,n,r,i,a){if(!e)return kn;var o=1;if(t===vW&&(t=6),r<0?(o=0,r=-r):r>15&&(o=2,r-=16),i<1||i>_W||n!==e0||r<8||r>15||t<0||t>9||a<0||a>AW)return Qi(e,kn);r===8&&(r=9);var s=new $W;return e.state=s,s.strm=e,s.wrap=o,s.gzhead=null,s.w_bits=r,s.w_size=1<<s.w_bits,s.w_mask=s.w_size-1,s.hash_bits=i+7,s.hash_size=1<<s.hash_bits,s.hash_mask=s.hash_size-1,s.hash_shift=~~((s.hash_bits+be-1)/be),s.window=new Wt.Buf8(s.w_size*2),s.head=new Wt.Buf16(s.hash_size),s.prev=new Wt.Buf16(s.w_size),s.lit_bufsize=1<<i+6,s.pending_buf_size=s.lit_bufsize*4,s.pending_buf=new Wt.Buf8(s.pending_buf_size),s.d_buf=1*s.lit_bufsize,s.l_buf=(1+2)*s.lit_bufsize,s.level=t,s.strategy=a,s.method=n,q6(e)}function GW(e,t){return W6(e,t,e0,CW,kW,EW)}function VW(e,t){var n,r,i,a;if(!e||!e.state||t>$6||t<0)return e?Qi(e,kn):kn;if(r=e.state,!e.output||!e.input&&e.avail_in!==0||r.status===wu&&t!==Yi)return Qi(e,e.avail_out===0?Qb:kn);if(r.strm=e,n=r.last_flush,r.last_flush=t,r.status===t0)if(r.wrap===2)e.adler=0,Se(r,31),Se(r,139),Se(r,8),r.gzhead?(Se(r,(r.gzhead.text?1:0)+(r.gzhead.hcrc?2:0)+(r.gzhead.extra?4:0)+(r.gzhead.name?8:0)+(r.gzhead.comment?16:0)),Se(r,r.gzhead.time&255),Se(r,r.gzhead.time>>8&255),Se(r,r.gzhead.time>>16&255),Se(r,r.gzhead.time>>24&255),Se(r,r.level===9?2:r.strategy>=Jd||r.level<2?4:0),Se(r,r.gzhead.os&255),r.gzhead.extra&&r.gzhead.extra.length&&(Se(r,r.gzhead.extra.length&255),Se(r,r.gzhead.extra.length>>8&255)),r.gzhead.hcrc&&(e.adler=Wi(e.adler,r.pending_buf,r.pending,0)),r.gzindex=0,r.status=Kb):(Se(r,0),Se(r,0),Se(r,0),Se(r,0),Se(r,0),Se(r,r.level===9?2:r.strategy>=Jd||r.level<2?4:0),Se(r,MW),r.status=bo);else{var o=e0+(r.w_bits-8<<4)<<8,s=-1;r.strategy>=Jd||r.level<2?s=0:r.level<6?s=1:r.level===6?s=2:s=3,o|=s<<6,r.strstart!==0&&(o|=PW),o+=31-o%31,r.status=bo,Au(r,o),r.strstart!==0&&(Au(r,e.adler>>>16),Au(r,e.adler&65535)),e.adler=1}if(r.status===Kb)if(r.gzhead.extra){for(i=r.pending;r.gzindex<(r.gzhead.extra.length&65535)&&!(r.pending===r.pending_buf_size&&(r.gzhead.hcrc&&r.pending>i&&(e.adler=Wi(e.adler,r.pending_buf,r.pending-i,i)),Ki(e),i=r.pending,r.pending===r.pending_buf_size));)Se(r,r.gzhead.extra[r.gzindex]&255),r.gzindex++;r.gzhead.hcrc&&r.pending>i&&(e.adler=Wi(e.adler,r.pending_buf,r.pending-i,i)),r.gzindex===r.gzhead.extra.length&&(r.gzindex=0,r.status=n0)}else r.status=n0;if(r.status===n0)if(r.gzhead.name){i=r.pending;do{if(r.pending===r.pending_buf_size&&(r.gzhead.hcrc&&r.pending>i&&(e.adler=Wi(e.adler,r.pending_buf,r.pending-i,i)),Ki(e),i=r.pending,r.pending===r.pending_buf_size)){a=1;break}r.gzindex<r.gzhead.name.length?a=r.gzhead.name.charCodeAt(r.gzindex++)&255:a=0,Se(r,a)}while(a!==0);r.gzhead.hcrc&&r.pending>i&&(e.adler=Wi(e.adler,r.pending_buf,r.pending-i,i)),a===0&&(r.gzindex=0,r.status=r0)}else r.status=r0;if(r.status===r0)if(r.gzhead.comment){i=r.pending;do{if(r.pending===r.pending_buf_size&&(r.gzhead.hcrc&&r.pending>i&&(e.adler=Wi(e.adler,r.pending_buf,r.pending-i,i)),Ki(e),i=r.pending,r.pending===r.pending_buf_size)){a=1;break}r.gzindex<r.gzhead.comment.length?a=r.gzhead.comment.charCodeAt(r.gzindex++)&255:a=0,Se(r,a)}while(a!==0);r.gzhead.hcrc&&r.pending>i&&(e.adler=Wi(e.adler,r.pending_buf,r.pending-i,i)),a===0&&(r.status=i0)}else r.status=i0;if(r.status===i0&&(r.gzhead.hcrc?(r.pending+2>r.pending_buf_size&&Ki(e),r.pending+2<=r.pending_buf_size&&(Se(r,e.adler&255),Se(r,e.adler>>8&255),e.adler=0,r.status=bo)):r.status=bo),r.pending!==0){if(Ki(e),e.avail_out===0)return r.last_flush=-1,Sr}else if(e.avail_in===0&&G6(t)<=G6(n)&&t!==Yi)return Qi(e,Qb);if(r.status===wu&&e.avail_in!==0)return Qi(e,Qb);if(e.avail_in!==0||r.lookahead!==0||t!==mo&&r.status!==wu){var c=r.strategy===Jd?zW(r,t):r.strategy===xW?NW(r,t):Ms[r.level].func(r,t);if((c===yo||c===Fs)&&(r.status=wu),c===yt||c===yo)return e.avail_out===0&&(r.last_flush=-1),Sr;if(c===xu&&(t===mW?Cn._tr_align(r):t!==$6&&(Cn._tr_stored_block(r,0,0,!1),t===bW&&(Xi(r.head),r.lookahead===0&&(r.strstart=0,r.block_start=0,r.insert=0))),Ki(e),e.avail_out===0))return r.last_flush=-1,Sr}return t!==Yi?Sr:r.wrap<=0?H6:(r.wrap===2?(Se(r,e.adler&255),Se(r,e.adler>>8&255),Se(r,e.adler>>16&255),Se(r,e.adler>>24&255),Se(r,e.total_in&255),Se(r,e.total_in>>8&255),Se(r,e.total_in>>16&255),Se(r,e.total_in>>24&255)):(Au(r,e.adler>>>16),Au(r,e.adler&65535)),Ki(e),r.wrap>0&&(r.wrap=-r.wrap),r.pending!==0?Sr:H6)}function jW(e){var t;return!e||!e.state?kn:(t=e.state.status,t!==t0&&t!==Kb&&t!==n0&&t!==r0&&t!==i0&&t!==bo&&t!==wu?Qi(e,kn):(e.state=null,t===bo?Qi(e,yW):Sr))}function qW(e,t){var n=t.length,r,i,a,o,s,c,l,u;if(!e||!e.state||(r=e.state,o=r.wrap,o===2||o===1&&r.status!==t0||r.lookahead))return kn;for(o===1&&(e.adler=U6(e.adler,t,n,0)),r.wrap=0,n>=r.w_size&&(o===0&&(Xi(r.head),r.strstart=0,r.block_start=0,r.insert=0),u=new Wt.Buf8(r.w_size),Wt.arraySet(u,t,n-r.w_size,r.w_size,0),t=u,n=r.w_size),s=e.avail_in,c=e.next_in,l=e.input,e.avail_in=n,e.next_in=0,e.input=t,vo(r);r.lookahead>=be;){i=r.strstart,a=r.lookahead-(be-1);do 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t,n,r,i,a,o=e.length,s=0;for(i=0;i<o;i++)n=e.charCodeAt(i),(n&64512)===55296&&i+1<o&&(r=e.charCodeAt(i+1),(r&64512)===56320&&(n=65536+(n-55296<<10)+(r-56320),i++)),s+=n<128?1:n<2048?2:n<65536?3:4;for(t=new a0.Buf8(s),a=0,i=0;a<s;i++)n=e.charCodeAt(i),(n&64512)===55296&&i+1<o&&(r=e.charCodeAt(i+1),(r&64512)===56320&&(n=65536+(n-55296<<10)+(r-56320),i++)),n<128?t[a++]=n:n<2048?(t[a++]=192|n>>>6,t[a++]=128|n&63):n<65536?(t[a++]=224|n>>>12,t[a++]=128|n>>>6&63,t[a++]=128|n&63):(t[a++]=240|n>>>18,t[a++]=128|n>>>12&63,t[a++]=128|n>>>6&63,t[a++]=128|n&63);return t};function Q6(e,t){if(t<65534&&(e.subarray&&Z6||!e.subarray&&Y6))return String.fromCharCode.apply(null,a0.shrinkBuf(e,t));for(var n="",r=0;r<t;r++)n+=String.fromCharCode(e[r]);return n}wo.buf2binstring=function(e){return Q6(e,e.length)},wo.binstring2buf=function(e){for(var t=new a0.Buf8(e.length),n=0,r=t.length;n<r;n++)t[n]=e.charCodeAt(n);return t},wo.buf2string=function(e,t){var n,r,i,a,o=t||e.length,s=new 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t=this.options;t.raw&&t.windowBits>0?t.windowBits=-t.windowBits:t.gzip&&t.windowBits>0&&t.windowBits<16&&(t.windowBits+=16),this.err=0,this.msg="",this.ended=!1,this.chunks=[],this.strm=new YW,this.strm.avail_out=0;var n=Su.deflateInit2(this.strm,t.level,t.method,t.windowBits,t.memLevel,t.strategy);if(n!==Os)throw new Error(ty[n]);if(t.header&&Su.deflateSetHeader(this.strm,t.header),t.dictionary){var r;if(typeof t.dictionary=="string"?r=ey.string2buf(t.dictionary):K6.call(t.dictionary)==="[object ArrayBuffer]"?r=new Uint8Array(t.dictionary):r=t.dictionary,n=Su.deflateSetDictionary(this.strm,r),n!==Os)throw new Error(ty[n]);this._dict_set=!0}}xo.prototype.push=function(e,t){var n=this.strm,r=this.options.chunkSize,i,a;if(this.ended)return!1;a=t===~~t?t:t===!0?ny:ZW,typeof e=="string"?n.input=ey.string2buf(e):K6.call(e)==="[object ArrayBuffer]"?n.input=new Uint8Array(e):n.input=e,n.next_in=0,n.avail_in=n.input.length;do{if(n.avail_out===0&&(n.output=new _u.Buf8(r),n.next_out=0,n.avail_out=r),i=Su.deflate(n,a),i!==J6&&i!==Os)return this.onEnd(i),this.ended=!0,!1;(n.avail_out===0||n.avail_in===0&&(a===ny||a===eC))&&(this.options.to==="string"?this.onData(ey.buf2binstring(_u.shrinkBuf(n.output,n.next_out))):this.onData(_u.shrinkBuf(n.output,n.next_out)))}while((n.avail_in>0||n.avail_out===0)&&i!==J6);return a===ny?(i=Su.deflateEnd(this.strm),this.onEnd(i),this.ended=!0,i===Os):(a===eC&&(this.onEnd(Os),n.avail_out=0),!0)},xo.prototype.onData=function(e){this.chunks.push(e)},xo.prototype.onEnd=function(e){e===Os&&(this.options.to==="string"?this.result=this.chunks.join(""):this.result=_u.flattenChunks(this.chunks)),this.chunks=[],this.err=e,this.msg=this.strm.msg};function ry(e,t){var n=new xo(t);if(n.push(e,!0),n.err)throw n.msg||ty[n.err];return n.result}function JW(e,t){return t=t||{},t.raw=!0,ry(e,t)}function eY(e,t){return t=t||{},t.gzip=!0,ry(e,t)}du.Deflate=xo,du.deflate=ry,du.deflateRaw=JW,du.gzip=eY;var Cu={},tr={},o0=30,tY=12,nY=function(t,n){var r,i,a,o,s,c,l,u,f,h,d,p,g,b,y,w,A,x,C,_,I,D,M,G,O;r=t.state,i=t.next_in,G=t.input,a=i+(t.avail_in-5),o=t.next_out,O=t.output,s=o-(n-t.avail_out),c=o+(t.avail_out-257),l=r.dmax,u=r.wsize,f=r.whave,h=r.wnext,d=r.window,p=r.hold,g=r.bits,b=r.lencode,y=r.distcode,w=(1<<r.lenbits)-1,A=(1<<r.distbits)-1;e:do{g<15&&(p+=G[i++]<<g,g+=8,p+=G[i++]<<g,g+=8),x=b[p&w];t:for(;;){if(C=x>>>24,p>>>=C,g-=C,C=x>>>16&255,C===0)O[o++]=x&65535;else if(C&16){_=x&65535,C&=15,C&&(g<C&&(p+=G[i++]<<g,g+=8),_+=p&(1<<C)-1,p>>>=C,g-=C),g<15&&(p+=G[i++]<<g,g+=8,p+=G[i++]<<g,g+=8),x=y[p&A];n:for(;;){if(C=x>>>24,p>>>=C,g-=C,C=x>>>16&255,C&16){if(I=x&65535,C&=15,g<C&&(p+=G[i++]<<g,g+=8,g<C&&(p+=G[i++]<<g,g+=8)),I+=p&(1<<C)-1,I>l){t.msg="invalid distance too far back",r.mode=o0;break e}if(p>>>=C,g-=C,C=o-s,I>C){if(C=I-C,C>f&&r.sane){t.msg="invalid distance too far back",r.mode=o0;break e}if(D=0,M=d,h===0){if(D+=u-C,C<_){_-=C;do O[o++]=d[D++];while(--C);D=o-I,M=O}}else if(h<C){if(D+=u+h-C,C-=h,C<_){_-=C;do O[o++]=d[D++];while(--C);if(D=0,h<_){C=h,_-=C;do O[o++]=d[D++];while(--C);D=o-I,M=O}}}else if(D+=h-C,C<_){_-=C;do O[o++]=d[D++];while(--C);D=o-I,M=O}for(;_>2;)O[o++]=M[D++],O[o++]=M[D++],O[o++]=M[D++],_-=3;_&&(O[o++]=M[D++],_>1&&(O[o++]=M[D++]))}else{D=o-I;do O[o++]=O[D++],O[o++]=O[D++],O[o++]=O[D++],_-=3;while(_>2);_&&(O[o++]=O[D++],_>1&&(O[o++]=O[D++]))}}else if(C&64){t.msg="invalid distance code",r.mode=o0;break e}else{x=y[(x&65535)+(p&(1<<C)-1)];continue n}break}}else if(C&64)if(C&32){r.mode=tY;break e}else{t.msg="invalid literal/length code",r.mode=o0;break e}else{x=b[(x&65535)+(p&(1<<C)-1)];continue t}break}}while(i<a&&o<c);_=g>>3,i-=_,g-=_<<3,p&=(1<<g)-1,t.next_in=i,t.next_out=o,t.avail_in=i<a?5+(a-i):5-(i-a),t.avail_out=o<c?257+(c-o):257-(o-c),r.hold=p,r.bits=g},tC=Kr,Ls=15,nC=852,rC=592,iC=0,iy=1,aC=2,rY=[3,4,5,6,7,8,9,10,11,13,15,17,19,23,27,31,35,43,51,59,67,83,99,115,131,163,195,227,258,0,0],iY=[16,16,16,16,16,16,16,16,17,17,17,17,18,18,18,18,19,19,19,19,20,20,20,20,21,21,21,21,16,72,78],aY=[1,2,3,4,5,7,9,13,17,25,33,49,65,97,129,193,257,385,513,769,1025,1537,2049,3073,4097,6145,8193,12289,16385,24577,0,0],oY=[16,16,16,16,17,17,18,18,19,19,20,20,21,21,22,22,23,23,24,24,25,25,26,26,27,27,28,28,29,29,64,64],sY=function(t,n,r,i,a,o,s,c){var l=c.bits,u=0,f=0,h=0,d=0,p=0,g=0,b=0,y=0,w=0,A=0,x,C,_,I,D,M=null,G=0,O,ae=new tC.Buf16(Ls+1),se=new tC.Buf16(Ls+1),ve=null,Pe=0,st,Ne,lt;for(u=0;u<=Ls;u++)ae[u]=0;for(f=0;f<i;f++)ae[n[r+f]]++;for(p=l,d=Ls;d>=1&&ae[d]===0;d--);if(p>d&&(p=d),d===0)return a[o++]=1<<24|64<<16|0,a[o++]=1<<24|64<<16|0,c.bits=1,0;for(h=1;h<d&&ae[h]===0;h++);for(p<h&&(p=h),y=1,u=1;u<=Ls;u++)if(y<<=1,y-=ae[u],y<0)return-1;if(y>0&&(t===iC||d!==1))return-1;for(se[1]=0,u=1;u<Ls;u++)se[u+1]=se[u]+ae[u];for(f=0;f<i;f++)n[r+f]!==0&&(s[se[n[r+f]]++]=f);if(t===iC?(M=ve=s,O=19):t===iy?(M=rY,G-=257,ve=iY,Pe-=257,O=256):(M=aY,ve=oY,O=-1),A=0,f=0,u=h,D=o,g=p,b=0,_=-1,w=1<<p,I=w-1,t===iy&&w>nC||t===aC&&w>rC)return 1;for(;;){st=u-b,s[f]<O?(Ne=0,lt=s[f]):s[f]>O?(Ne=ve[Pe+s[f]],lt=M[G+s[f]]):(Ne=32+64,lt=0),x=1<<u-b,C=1<<g,h=C;do C-=x,a[D+(A>>b)+C]=st<<24|Ne<<16|lt|0;while(C!==0);for(x=1<<u-1;A&x;)x>>=1;if(x!==0?(A&=x-1,A+=x):A=0,f++,--ae[u]===0){if(u===d)break;u=n[r+s[f]]}if(u>p&&(A&I)!==_){for(b===0&&(b=p),D+=h,g=u-b,y=1<<g;g+b<d&&(y-=ae[g+b],!(y<=0));)g++,y<<=1;if(w+=1<<g,t===iy&&w>nC||t===aC&&w>rC)return 1;_=A&I,a[_]=p<<24|g<<16|D-o|0}}return A!==0&&(a[D+A]=u-b<<24|64<<16|0),c.bits=p,0},mn=Kr,ay=N6,Cr=z6,cY=nY,ku=sY,lY=0,oC=1,sC=2,cC=4,uY=5,s0=6,Ao=0,fY=1,hY=2,Tn=-2,lC=-3,uC=-4,dY=-5,fC=8,hC=1,dC=2,pC=3,gC=4,mC=5,bC=6,yC=7,vC=8,wC=9,xC=10,c0=11,ei=12,oy=13,AC=14,sy=15,EC=16,SC=17,_C=18,CC=19,l0=20,u0=21,kC=22,TC=23,IC=24,RC=25,DC=26,cy=27,BC=28,FC=29,Ke=30,PC=31,pY=32,gY=852,mY=592,bY=15,yY=bY;function MC(e){return(e>>>24&255)+(e>>>8&65280)+((e&65280)<<8)+((e&255)<<24)}function vY(){this.mode=0,this.last=!1,this.wrap=0,this.havedict=!1,this.flags=0,this.dmax=0,this.check=0,this.total=0,this.head=null,this.wbits=0,this.wsize=0,this.whave=0,this.wnext=0,this.window=null,this.hold=0,this.bits=0,this.length=0,this.offset=0,this.extra=0,this.lencode=null,this.distcode=null,this.lenbits=0,this.distbits=0,this.ncode=0,this.nlen=0,this.ndist=0,this.have=0,this.next=null,this.lens=new mn.Buf16(320),this.work=new mn.Buf16(288),this.lendyn=null,this.distdyn=null,this.sane=0,this.back=0,this.was=0}function OC(e){var t;return!e||!e.state?Tn:(t=e.state,e.total_in=e.total_out=t.total=0,e.msg="",t.wrap&&(e.adler=t.wrap&1),t.mode=hC,t.last=0,t.havedict=0,t.dmax=32768,t.head=null,t.hold=0,t.bits=0,t.lencode=t.lendyn=new mn.Buf32(gY),t.distcode=t.distdyn=new mn.Buf32(mY),t.sane=1,t.back=-1,Ao)}function LC(e){var t;return!e||!e.state?Tn:(t=e.state,t.wsize=0,t.whave=0,t.wnext=0,OC(e))}function NC(e,t){var n,r;return!e||!e.state||(r=e.state,t<0?(n=0,t=-t):(n=(t>>4)+1,t<48&&(t&=15)),t&&(t<8||t>15))?Tn:(r.window!==null&&r.wbits!==t&&(r.window=null),r.wrap=n,r.wbits=t,LC(e))}function zC(e,t){var n,r;return e?(r=new vY,e.state=r,r.window=null,n=NC(e,t),n!==Ao&&(e.state=null),n):Tn}function wY(e){return zC(e,yY)}var UC=!0,ly,uy;function xY(e){if(UC){var t;for(ly=new mn.Buf32(512),uy=new mn.Buf32(32),t=0;t<144;)e.lens[t++]=8;for(;t<256;)e.lens[t++]=9;for(;t<280;)e.lens[t++]=7;for(;t<288;)e.lens[t++]=8;for(ku(oC,e.lens,0,288,ly,0,e.work,{bits:9}),t=0;t<32;)e.lens[t++]=5;ku(sC,e.lens,0,32,uy,0,e.work,{bits:5}),UC=!1}e.lencode=ly,e.lenbits=9,e.distcode=uy,e.distbits=5}function $C(e,t,n,r){var i,a=e.state;return a.window===null&&(a.wsize=1<<a.wbits,a.wnext=0,a.whave=0,a.window=new mn.Buf8(a.wsize)),r>=a.wsize?(mn.arraySet(a.window,t,n-a.wsize,a.wsize,0),a.wnext=0,a.whave=a.wsize):(i=a.wsize-a.wnext,i>r&&(i=r),mn.arraySet(a.window,t,n-r,i,a.wnext),r-=i,r?(mn.arraySet(a.window,t,n-r,r,0),a.wnext=r,a.whave=a.wsize):(a.wnext+=i,a.wnext===a.wsize&&(a.wnext=0),a.whave<a.wsize&&(a.whave+=i))),0}function AY(e,t){var n,r,i,a,o,s,c,l,u,f,h,d,p,g,b=0,y,w,A,x,C,_,I,D,M=new mn.Buf8(4),G,O,ae=[16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15];if(!e||!e.state||!e.output||!e.input&&e.avail_in!==0)return Tn;n=e.state,n.mode===ei&&(n.mode=oy),o=e.next_out,i=e.output,c=e.avail_out,a=e.next_in,r=e.input,s=e.avail_in,l=n.hold,u=n.bits,f=s,h=c,D=Ao;e:for(;;)switch(n.mode){case hC:if(n.wrap===0){n.mode=oy;break}for(;u<16;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(n.wrap&2&&l===35615){n.check=0,M[0]=l&255,M[1]=l>>>8&255,n.check=Cr(n.check,M,2,0),l=0,u=0,n.mode=dC;break}if(n.flags=0,n.head&&(n.head.done=!1),!(n.wrap&1)||(((l&255)<<8)+(l>>8))%31){e.msg="incorrect header check",n.mode=Ke;break}if((l&15)!==fC){e.msg="unknown compression method",n.mode=Ke;break}if(l>>>=4,u-=4,I=(l&15)+8,n.wbits===0)n.wbits=I;else if(I>n.wbits){e.msg="invalid window size",n.mode=Ke;break}n.dmax=1<<I,e.adler=n.check=1,n.mode=l&512?xC:ei,l=0,u=0;break;case dC:for(;u<16;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(n.flags=l,(n.flags&255)!==fC){e.msg="unknown compression method",n.mode=Ke;break}if(n.flags&57344){e.msg="unknown header flags set",n.mode=Ke;break}n.head&&(n.head.text=l>>8&1),n.flags&512&&(M[0]=l&255,M[1]=l>>>8&255,n.check=Cr(n.check,M,2,0)),l=0,u=0,n.mode=pC;case pC:for(;u<32;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}n.head&&(n.head.time=l),n.flags&512&&(M[0]=l&255,M[1]=l>>>8&255,M[2]=l>>>16&255,M[3]=l>>>24&255,n.check=Cr(n.check,M,4,0)),l=0,u=0,n.mode=gC;case gC:for(;u<16;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}n.head&&(n.head.xflags=l&255,n.head.os=l>>8),n.flags&512&&(M[0]=l&255,M[1]=l>>>8&255,n.check=Cr(n.check,M,2,0)),l=0,u=0,n.mode=mC;case mC:if(n.flags&1024){for(;u<16;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}n.length=l,n.head&&(n.head.extra_len=l),n.flags&512&&(M[0]=l&255,M[1]=l>>>8&255,n.check=Cr(n.check,M,2,0)),l=0,u=0}else n.head&&(n.head.extra=null);n.mode=bC;case bC:if(n.flags&1024&&(d=n.length,d>s&&(d=s),d&&(n.head&&(I=n.head.extra_len-n.length,n.head.extra||(n.head.extra=new 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e;s--,l+=r[a++]<<u,u+=8}e.adler=n.check=MC(l),l=0,u=0,n.mode=c0;case c0:if(n.havedict===0)return e.next_out=o,e.avail_out=c,e.next_in=a,e.avail_in=s,n.hold=l,n.bits=u,hY;e.adler=n.check=1,n.mode=ei;case ei:if(t===uY||t===s0)break e;case oy:if(n.last){l>>>=u&7,u-=u&7,n.mode=cy;break}for(;u<3;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}switch(n.last=l&1,l>>>=1,u-=1,l&3){case 0:n.mode=AC;break;case 1:if(xY(n),n.mode=l0,t===s0){l>>>=2,u-=2;break e}break;case 2:n.mode=SC;break;case 3:e.msg="invalid block type",n.mode=Ke}l>>>=2,u-=2;break;case AC:for(l>>>=u&7,u-=u&7;u<32;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if((l&65535)!==(l>>>16^65535)){e.msg="invalid stored block lengths",n.mode=Ke;break}if(n.length=l&65535,l=0,u=0,n.mode=sy,t===s0)break e;case sy:n.mode=EC;case EC:if(d=n.length,d){if(d>s&&(d=s),d>c&&(d=c),d===0)break e;mn.arraySet(i,r,a,d,o),s-=d,a+=d,c-=d,o+=d,n.length-=d;break}n.mode=ei;break;case SC:for(;u<14;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(n.nlen=(l&31)+257,l>>>=5,u-=5,n.ndist=(l&31)+1,l>>>=5,u-=5,n.ncode=(l&15)+4,l>>>=4,u-=4,n.nlen>286||n.ndist>30){e.msg="too many length or distance symbols",n.mode=Ke;break}n.have=0,n.mode=_C;case _C:for(;n.have<n.ncode;){for(;u<3;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}n.lens[ae[n.have++]]=l&7,l>>>=3,u-=3}for(;n.have<19;)n.lens[ae[n.have++]]=0;if(n.lencode=n.lendyn,n.lenbits=7,G={bits:n.lenbits},D=ku(lY,n.lens,0,19,n.lencode,0,n.work,G),n.lenbits=G.bits,D){e.msg="invalid code lengths set",n.mode=Ke;break}n.have=0,n.mode=CC;case CC:for(;n.have<n.nlen+n.ndist;){for(;b=n.lencode[l&(1<<n.lenbits)-1],y=b>>>24,w=b>>>16&255,A=b&65535,!(y<=u);){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(A<16)l>>>=y,u-=y,n.lens[n.have++]=A;else{if(A===16){for(O=y+2;u<O;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(l>>>=y,u-=y,n.have===0){e.msg="invalid bit length repeat",n.mode=Ke;break}I=n.lens[n.have-1],d=3+(l&3),l>>>=2,u-=2}else if(A===17){for(O=y+3;u<O;){if(s===0)break 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this.unsigned||this.high>=0},X.isOdd=function(){return(this.low&1)===1},X.isEven=function(){return(this.low&1)===0},X.equals=function(t){return on(t)||(t=nr(t)),this.unsigned!==t.unsigned&&this.high>>>31===1&&t.high>>>31===1?!1:this.high===t.high&&this.low===t.low},X.eq=X.equals,X.notEquals=function(t){return!this.eq(t)},X.neq=X.notEquals,X.ne=X.notEquals,X.lessThan=function(t){return this.comp(t)<0},X.lt=X.lessThan,X.lessThanOrEqual=function(t){return this.comp(t)<=0},X.lte=X.lessThanOrEqual,X.le=X.lessThanOrEqual,X.greaterThan=function(t){return this.comp(t)>0},X.gt=X.greaterThan,X.greaterThanOrEqual=function(t){return this.comp(t)>=0},X.gte=X.greaterThanOrEqual,X.ge=X.greaterThanOrEqual,X.compare=function(t){if(on(t)||(t=nr(t)),this.eq(t))return 0;var n=this.isNegative(),r=t.isNegative();return n&&!r?-1:!n&&r?1:this.unsigned?t.high>>>0>this.high>>>0||t.high===this.high&&t.low>>>0>this.low>>>0?-1:1:this.sub(t).isNegative()?-1:1},X.comp=X.compare,X.negate=function(){return!this.unsigned&&this.eq(sn)?sn:this.not().add(Us)},X.neg=X.negate,X.add=function(t){on(t)||(t=nr(t));var n=this.high>>>16,r=this.high&65535,i=this.low>>>16,a=this.low&65535,o=t.high>>>16,s=t.high&65535,c=t.low>>>16,l=t.low&65535,u=0,f=0,h=0,d=0;return d+=a+l,h+=d>>>16,d&=65535,h+=i+c,f+=h>>>16,h&=65535,f+=r+s,u+=f>>>16,f&=65535,u+=n+o,u&=65535,Ge(h<<16|d,u<<16|f,this.unsigned)},X.subtract=function(t){return on(t)||(t=nr(t)),this.add(t.neg())},X.sub=X.subtract,X.multiply=function(t){if(this.isZero())return Dn;if(on(t)||(t=nr(t)),In){var n=In.mul(this.low,this.high,t.low,t.high);return Ge(n,In.get_high(),this.unsigned)}if(t.isZero())return Dn;if(this.eq(sn))return t.isOdd()?sn:Dn;if(t.eq(sn))return this.isOdd()?sn:Dn;if(this.isNegative())return t.isNegative()?this.neg().mul(t.neg()):this.neg().mul(t).neg();if(t.isNegative())return this.mul(t.neg()).neg();if(this.lt(XC)&&t.lt(XC))return Rn(this.toNumber()*t.toNumber(),this.unsigned);var r=this.high>>>16,i=this.high&65535,a=this.low>>>16,o=this.low&65535,s=t.high>>>16,c=t.high&65535,l=t.low>>>16,u=t.low&65535,f=0,h=0,d=0,p=0;return p+=o*u,d+=p>>>16,p&=65535,d+=a*u,h+=d>>>16,d&=65535,d+=o*l,h+=d>>>16,d&=65535,h+=i*u,f+=h>>>16,h&=65535,h+=a*l,f+=h>>>16,h&=65535,h+=o*c,f+=h>>>16,h&=65535,f+=r*u+i*l+a*c+o*s,f&=65535,Ge(d<<16|p,f<<16|h,this.unsigned)},X.mul=X.multiply,X.divide=function(t){if(on(t)||(t=nr(t)),t.isZero())throw Error("division by zero");if(In){if(!this.unsigned&&this.high===-2147483648&&t.low===-1&&t.high===-1)return this;var n=(this.unsigned?In.div_u:In.div_s)(this.low,this.high,t.low,t.high);return Ge(n,In.get_high(),this.unsigned)}if(this.isZero())return this.unsigned?_o:Dn;var r,i,a;if(this.unsigned){if(t.unsigned||(t=t.toUnsigned()),t.gt(this))return _o;if(t.gt(this.shru(1)))return KC;a=_o}else{if(this.eq(sn)){if(t.eq(Us)||t.eq(py))return sn;if(t.eq(sn))return Us;var o=this.shr(1);return r=o.div(t).shl(1),r.eq(Dn)?t.isNegative()?Us:py:(i=this.sub(t.mul(r)),a=r.add(i.div(t)),a)}else if(t.eq(sn))return this.unsigned?_o:Dn;if(this.isNegative())return t.isNegative()?this.neg().div(t.neg()):this.neg().div(t).neg();if(t.isNegative())return this.div(t.neg()).neg();a=Dn}for(i=this;i.gte(t);){r=Math.max(1,Math.floor(i.toNumber()/t.toNumber()));for(var s=Math.ceil(Math.log(r)/Math.LN2),c=s<=48?1:d0(2,s-48),l=Rn(r),u=l.mul(t);u.isNegative()||u.gt(i);)r-=c,l=Rn(r,this.unsigned),u=l.mul(t);l.isZero()&&(l=Us),a=a.add(l),i=i.sub(u)}return a},X.div=X.divide,X.modulo=function(t){if(on(t)||(t=nr(t)),In){var n=(this.unsigned?In.rem_u:In.rem_s)(this.low,this.high,t.low,t.high);return Ge(n,In.get_high(),this.unsigned)}return this.sub(this.div(t).mul(t))},X.mod=X.modulo,X.rem=X.modulo,X.not=function(){return Ge(~this.low,~this.high,this.unsigned)},X.and=function(t){return on(t)||(t=nr(t)),Ge(this.low&t.low,this.high&t.high,this.unsigned)},X.or=function(t){return on(t)||(t=nr(t)),Ge(this.low|t.low,this.high|t.high,this.unsigned)},X.xor=function(t){return on(t)||(t=nr(t)),Ge(this.low^t.low,this.high^t.high,this.unsigned)},X.shiftLeft=function(t){return on(t)&&(t=t.toInt()),(t&=63)===0?this:t<32?Ge(this.low<<t,this.high<<t|this.low>>>32-t,this.unsigned):Ge(0,this.low<<t-32,this.unsigned)},X.shl=X.shiftLeft,X.shiftRight=function(t){return on(t)&&(t=t.toInt()),(t&=63)===0?this:t<32?Ge(this.low>>>t|this.high<<32-t,this.high>>t,this.unsigned):Ge(this.high>>t-32,this.high>=0?0:-1,this.unsigned)},X.shr=X.shiftRight,X.shiftRightUnsigned=function(t){if(on(t)&&(t=t.toInt()),t&=63,t===0)return this;var n=this.high;if(t<32){var r=this.low;return Ge(r>>>t|n<<32-t,n>>>t,this.unsigned)}else return t===32?Ge(n,0,this.unsigned):Ge(n>>>t-32,0,this.unsigned)},X.shru=X.shiftRightUnsigned,X.shr_u=X.shiftRightUnsigned,X.toSigned=function(){return this.unsigned?Ge(this.low,this.high,!1):this},X.toUnsigned=function(){return this.unsigned?this:Ge(this.low,this.high,!0)},X.toBytes=function(t){return t?this.toBytesLE():this.toBytesBE()},X.toBytesLE=function(){var t=this.high,n=this.low;return[n&255,n>>>8&255,n>>>16&255,n>>>24,t&255,t>>>8&255,t>>>16&255,t>>>24]},X.toBytesBE=function(){var t=this.high,n=this.low;return[t>>>24,t>>>16&255,t>>>8&255,t&255,n>>>24,n>>>16&255,n>>>8&255,n&255]},He.fromBytes=function(t,n,r){return r?He.fromBytesLE(t,n):He.fromBytesBE(t,n)},He.fromBytesLE=function(t,n){return new He(t[0]|t[1]<<8|t[2]<<16|t[3]<<24,t[4]|t[5]<<8|t[6]<<16|t[7]<<24,n)},He.fromBytesBE=function(t,n){return new He(t[4]<<24|t[5]<<16|t[6]<<8|t[7],t[0]<<24|t[1]<<16|t[2]<<8|t[3],n)};const p0=uu(MY),g0=1;class LY{constructor({filehandle:t,path:n}){if(t)this.filehandle=t;else if(n)this.filehandle=new kt(n);else throw new TypeError("either filehandle or path must be defined")}_readLongWithOverflow(t,n=0,r=!0){const i=p0.fromBytesLE(t.slice(n,n+8),r);if(i.greaterThan(Number.MAX_SAFE_INTEGER)||i.lessThan(Number.MIN_SAFE_INTEGER))throw new TypeError("integer overflow");return i.toNumber()}_getIndex(){return this.index||(this.index=this._readIndex()),this.index}async _readIndex(){let t=we.Buffer.allocUnsafe(8);await this.filehandle.read(t,0,8,0);const n=this._readLongWithOverflow(t,0,!0);if(!n)return[[0,0]];const r=new Array(n+1);r[0]=[0,0];const i=8*2*n;if(i>Number.MAX_SAFE_INTEGER)throw new TypeError("integer overflow");t=we.Buffer.allocUnsafe(i),await this.filehandle.read(t,0,i,8);for(let a=0;a<n;a+=1){const o=this._readLongWithOverflow(t,a*16),s=this._readLongWithOverflow(t,a*16+8);r[a+1]=[o,s]}return r}async getLastBlock(){const t=await this._getIndex();if(t.length)return t[t.length-1]}async getRelevantBlocksForRead(t,n){const r=n+t;if(t===0)return[];const i=await this._getIndex(),a=[],o=(h,d)=>{const p=h[g0],g=d?d[g0]:1/0;return p<=n&&g>n?0:p<n?-1:1};let s=0,c=i.length-1,l=Math.floor(i.length/2),u=o(i[l],i[l+1]);for(;u!==0;)u>0?c=l-1:u<0&&(s=l+1),l=Math.ceil((c-s)/2)+s,u=o(i[l],i[l+1]);a.push(i[l]);let f=l+1;for(;f<i.length&&(a.push(i[f]),!(i[f][g0]>=r));f+=1);return a[a.length-1][g0]<r&&a.push([]),a}}class t5{constructor({filehandle:t,path:n,gziFilehandle:r,gziPath:i}){if(t)this.filehandle=t;else if(n)this.filehandle=new kt(n);else throw new TypeError("either filehandle or path must be defined");if(!r&&!i&&!n)throw new TypeError("either gziFilehandle or gziPath must be defined");this.gzi=new LY({filehandle:r,path:!r&&!i&&n?i:`${n}.gzi`})}async stat(){const t=await this.filehandle.stat();return Object.assign(t,{size:await this.getUncompressedFileSize(),blocks:void 0,blksize:void 0})}async getUncompressedFileSize(){const[,t]=await this.gzi.getLastBlock(),{size:n}=await this.filehandle.stat(),r=we.Buffer.allocUnsafe(4),{bytesRead:i}=await this.filehandle.read(r,0,4,n-28-4);if(i!==4)throw new Error("read error");const a=r.readUInt32LE(0);return t+a}async _readAndUncompressBlock(t,[n],[r]){let i=r;i||(i=(await this.filehandle.stat()).size);const a=i-n;return await this.filehandle.read(t,0,a,n),await ea(t.slice(0,a))}async read(t,n,r,i){const a=await this.gzi.getRelevantBlocksForRead(r,i),o=we.Buffer.allocUnsafe(32768*2);let s=n,c=0;for(let l=0;l<a.length-1;l+=1){const u=await this._readAndUncompressBlock(o,a[l],a[l+1]),[,f]=a[l],h=f>=i?0:i-f,d=Math.min(i+r,f+u.length)-f;h>=0&&h<u.length&&(u.copy(t,s,h,d),s+=d-h,c+=d-h)}return{bytesRead:c,buffer:t}}}function n5(e,t){return e.offset+e.lineBytes*Math.floor(t/e.lineLength)+t%e.lineLength}async function NY(e,t){const n=await e.readFile(t);if(!(n&&n.length))throw new Error("No data read from FASTA index (FAI) file");let r=0,i;const a=n.toString("utf8").split(/\r?\n/).filter(o=>/\S/.test(o)).map(o=>o.split(" ")).filter(o=>o[0]!=="").map(o=>((!i||i.name!==o[0])&&(i={name:o[0],id:r},r+=1),{id:i.id,name:o[0],length:+o[1],start:0,end:+o[1],offset:+o[2],lineLength:+o[3],lineBytes:+o[4]}));return{name:Object.fromEntries(a.map(o=>[o.name,o])),id:Object.fromEntries(a.map(o=>[o.id,o]))}}class r5{constructor({fasta:t,fai:n,path:r,faiPath:i,chunkSizeLimit:a=1e6}){if(t)this.fasta=t;else if(r)this.fasta=new kt(r);else throw new Error("Need to pass filehandle for fasta or path to localfile");if(n)this.fai=n;else if(i)this.fai=new kt(i);else if(r)this.fai=new kt(`${r}.fai`);else throw new Error("Need to pass filehandle for or path to localfile");this.chunkSizeLimit=a}async _getIndexes(t){return this.indexes||(this.indexes=NY(this.fai,t)),this.indexes}async getSequenceNames(t){return Object.keys((await this._getIndexes(t)).name)}async getSequenceSizes(t){const n={},r=await this._getIndexes(t),i=Object.values(r.id);for(let a=0;a<i.length;a+=1)n[i[a].name]=i[a].length;return n}async getSequenceSize(t,n){var r;return(r=(await this._getIndexes(n)).name[t])===null||r===void 0?void 0:r.length}async hasReferenceSequence(t,n){return!!(await this._getIndexes(n)).name[t]}async getResiduesById(t,n,r,i){const a=(await this._getIndexes(i)).id[t];if(a)return this._fetchFromIndexEntry(a,n,r,i)}async getResiduesByName(t,n,r,i){const a=(await this._getIndexes(i)).name[t];if(a)return this._fetchFromIndexEntry(a,n,r,i)}async getSequence(t,n,r,i){return this.getResiduesByName(t,n,r,i)}async _fetchFromIndexEntry(t,n=0,r,i){let a=r;if(n<0)throw new TypeError("regionStart cannot be less than 0");if((a===void 0||a>t.length)&&(a=t.length),n>=a)return"";const o=n5(t,n),s=n5(t,a)-o;if(s>this.chunkSizeLimit)throw new Error(`data size of ${s.toLocaleString()} bytes exceeded chunk size limit of ${this.chunkSizeLimit.toLocaleString()} bytes`);const c=Buffer.allocUnsafe(s);return await this.fasta.read(c,0,s,o,i),c.toString("utf8").replace(/\s+/g,"")}}class zY extends r5{constructor({fasta:t,path:n,fai:r,faiPath:i,gzi:a,gziPath:o,chunkSizeLimit:s}){super({fasta:t,path:n,fai:r,faiPath:i,chunkSizeLimit:s}),t&&a?this.fasta=new t5({filehandle:t,gziFilehandle:a}):n&&o&&(this.fasta=new t5({path:n,gziPath:o}))}}function i5(e){return e.split(">").filter(t=>/\S/.test(t)).map(t=>{const[n,...r]=t.split(`
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`),[i,...a]=n.split(" "),o=r.join("").replace(/\s/g,"");return{id:i,description:a.join(" "),sequence:o}})}class UY{constructor({fasta:t,path:n}){if(t)this.fasta=t;else if(n)this.fasta=new kt(n);else throw new Error("Need to pass fasta or path");this.data=this.fasta.readFile().then(r=>{const i=r.toString("utf8");return i5(i)})}async fetch(t,n,r){const a=(await this.data).find(s=>s.id===t),o=r-n;if(!a)throw new Error(`no sequence with id ${t} exists`);return a.sequence.substr(n,o)}async getSequenceNames(){return(await this.data).map(n=>n.id)}}const $Y=Object.freeze(Object.defineProperty({__proto__:null,BgzipIndexedFasta:zY,FetchableSmallFasta:UY,IndexedFasta:r5,parseSmallFasta:i5},Symbol.toStringTag,{value:"Module"})),m0=BigInt(32);function HY(e,t,n){const r=+!!n,i=+!n;return BigInt(e.getInt32(t,n)*i+e.getInt32(t+4,n)*r)<<m0|BigInt(e.getUint32(t,n)*r+e.getUint32(t+4,n)*i)}function GY(e,t,n){const r=e.getUint32(t,n),i=e.getUint32(t+4,n),a=+!!n,o=+!n;return BigInt(r*o+i*a)<<m0|BigInt(r*a+i*o)}function VY(e,t,n,r){const i=Number(n>>m0),a=Number(n&BigInt(4294967295));r?(e.setInt32(t+4,i,r),e.setUint32(t,a,r)):(e.setInt32(t,i,r),e.setUint32(t+4,a,r))}function jY(e,t,n,r){const i=Number(n>>m0),a=Number(n&BigInt(4294967295));r?(e.setUint32(t+4,i,r),e.setUint32(t,a,r)):(e.setUint32(t,i,r),e.setUint32(t+4,a,r))}"getBigInt64"in DataView||(DataView.prototype.getBigInt64=function(e,t){return HY(this,e,t)}),"getBigUint64"in DataView||(DataView.prototype.getBigUint64=function(e,t){return GY(this,e,t)}),"setBigInt64"in DataView||(DataView.prototype.setBigInt64=function(e,t,n){VY(this,e,t,n)}),"setBigUint64"in DataView||(DataView.prototype.setBigUint64=function(e,t,n){jY(this,e,t,n)});class qY{constructor(t,n){this.code="",this.scopes=[["vars"]],this.bitFields=[],this.tmpVariableCount=0,this.references=new Map,this.imports=[],this.reverseImports=new Map,this.useContextVariables=!1,this.importPath=t,this.useContextVariables=n}generateVariable(t){const n=[...this.scopes[this.scopes.length-1]];return t&&n.push(t),n.join(".")}generateOption(t){switch(typeof t){case"number":return t.toString();case"string":return this.generateVariable(t);case"function":return`${this.addImport(t)}.call(${this.generateVariable()}, vars)`}}generateError(t){this.pushCode(`throw new Error(${t});`)}generateTmpVariable(){return"$tmp"+this.tmpVariableCount++}pushCode(t){this.code+=t+`
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`}pushPath(t){t&&this.scopes[this.scopes.length-1].push(t)}popPath(t){t&&this.scopes[this.scopes.length-1].pop()}pushScope(t){this.scopes.push([t])}popScope(){this.scopes.pop()}addImport(t){if(!this.importPath)return`(${t})`;let n=this.reverseImports.get(t);return n||(n=this.imports.push(t)-1,this.reverseImports.set(t,n)),`${this.importPath}[${n}]`}addReference(t){this.references.has(t)||this.references.set(t,{resolved:!1,requested:!1})}markResolved(t){const n=this.references.get(t);n&&(n.resolved=!0)}markRequested(t){t.forEach(n=>{const r=this.references.get(n);r&&(r.requested=!0)})}getUnresolvedReferences(){return Array.from(this.references).filter(([t,n])=>!n.resolved&&!n.requested).map(([t,n])=>t)}}const rr=new Map,Co="___parser_",ir={uint8:1,uint16le:2,uint16be:2,uint32le:4,uint32be:4,int8:1,int16le:2,int16be:2,int32le:4,int32be:4,int64be:8,int64le:8,uint64be:8,uint64le:8,floatle:4,floatbe:4,doublele:8,doublebe:8},b0={uint8:"Uint8",uint16le:"Uint16",uint16be:"Uint16",uint32le:"Uint32",uint32be:"Uint32",int8:"Int8",int16le:"Int16",int16be:"Int16",int32le:"Int32",int32be:"Int32",int64be:"BigInt64",int64le:"BigInt64",uint64be:"BigUint64",uint64le:"BigUint64",floatle:"Float32",floatbe:"Float32",doublele:"Float64",doublebe:"Float64"},y0={uint8:!1,uint16le:!0,uint16be:!1,uint32le:!0,uint32be:!1,int8:!1,int16le:!0,int16be:!1,int32le:!0,int32be:!1,int64be:!1,int64le:!0,uint64be:!1,uint64le:!0,floatle:!0,floatbe:!1,doublele:!0,doublebe:!1};let Fe=class sr{constructor(){this.varName="",this.type="",this.options={},this.endian="be",this.useContextVariables=!1}static start(){return new sr}primitiveGenerateN(t,n){const r=b0[t],i=y0[t];n.pushCode(`${n.generateVariable(this.varName)} = dataView.get${r}(offset, ${i});`),n.pushCode(`offset += ${ir[t]};`)}primitiveN(t,n,r){return this.setNextParser(t,n,r)}useThisEndian(t){return t+this.endian.toLowerCase()}uint8(t,n={}){return this.primitiveN("uint8",t,n)}uint16(t,n={}){return this.primitiveN(this.useThisEndian("uint16"),t,n)}uint16le(t,n={}){return this.primitiveN("uint16le",t,n)}uint16be(t,n={}){return this.primitiveN("uint16be",t,n)}uint32(t,n={}){return this.primitiveN(this.useThisEndian("uint32"),t,n)}uint32le(t,n={}){return this.primitiveN("uint32le",t,n)}uint32be(t,n={}){return this.primitiveN("uint32be",t,n)}int8(t,n={}){return this.primitiveN("int8",t,n)}int16(t,n={}){return this.primitiveN(this.useThisEndian("int16"),t,n)}int16le(t,n={}){return this.primitiveN("int16le",t,n)}int16be(t,n={}){return this.primitiveN("int16be",t,n)}int32(t,n={}){return this.primitiveN(this.useThisEndian("int32"),t,n)}int32le(t,n={}){return this.primitiveN("int32le",t,n)}int32be(t,n={}){return this.primitiveN("int32be",t,n)}bigIntVersionCheck(){if(!DataView.prototype.getBigInt64)throw new Error("BigInt64 is unsupported on this runtime")}int64(t,n={}){return this.bigIntVersionCheck(),this.primitiveN(this.useThisEndian("int64"),t,n)}int64be(t,n={}){return this.bigIntVersionCheck(),this.primitiveN("int64be",t,n)}int64le(t,n={}){return this.bigIntVersionCheck(),this.primitiveN("int64le",t,n)}uint64(t,n={}){return this.bigIntVersionCheck(),this.primitiveN(this.useThisEndian("uint64"),t,n)}uint64be(t,n={}){return this.bigIntVersionCheck(),this.primitiveN("uint64be",t,n)}uint64le(t,n={}){return this.bigIntVersionCheck(),this.primitiveN("uint64le",t,n)}floatle(t,n={}){return this.primitiveN("floatle",t,n)}floatbe(t,n={}){return this.primitiveN("floatbe",t,n)}doublele(t,n={}){return this.primitiveN("doublele",t,n)}doublebe(t,n={}){return this.primitiveN("doublebe",t,n)}bitN(t,n,r){return r.length=t,this.setNextParser("bit",n,r)}bit1(t,n={}){return this.bitN(1,t,n)}bit2(t,n={}){return this.bitN(2,t,n)}bit3(t,n={}){return this.bitN(3,t,n)}bit4(t,n={}){return this.bitN(4,t,n)}bit5(t,n={}){return this.bitN(5,t,n)}bit6(t,n={}){return this.bitN(6,t,n)}bit7(t,n={}){return this.bitN(7,t,n)}bit8(t,n={}){return this.bitN(8,t,n)}bit9(t,n={}){return this.bitN(9,t,n)}bit10(t,n={}){return this.bitN(10,t,n)}bit11(t,n={}){return this.bitN(11,t,n)}bit12(t,n={}){return this.bitN(12,t,n)}bit13(t,n={}){return this.bitN(13,t,n)}bit14(t,n={}){return this.bitN(14,t,n)}bit15(t,n={}){return this.bitN(15,t,n)}bit16(t,n={}){return this.bitN(16,t,n)}bit17(t,n={}){return this.bitN(17,t,n)}bit18(t,n={}){return this.bitN(18,t,n)}bit19(t,n={}){return this.bitN(19,t,n)}bit20(t,n={}){return this.bitN(20,t,n)}bit21(t,n={}){return this.bitN(21,t,n)}bit22(t,n={}){return this.bitN(22,t,n)}bit23(t,n={}){return this.bitN(23,t,n)}bit24(t,n={}){return this.bitN(24,t,n)}bit25(t,n={}){return this.bitN(25,t,n)}bit26(t,n={}){return this.bitN(26,t,n)}bit27(t,n={}){return this.bitN(27,t,n)}bit28(t,n={}){return this.bitN(28,t,n)}bit29(t,n={}){return this.bitN(29,t,n)}bit30(t,n={}){return this.bitN(30,t,n)}bit31(t,n={}){return this.bitN(31,t,n)}bit32(t,n={}){return this.bitN(32,t,n)}namely(t){return rr.set(t,this),this.alias=t,this}skip(t,n={}){return this.seek(t,n)}seek(t,n={}){if(n.assert)throw new Error("assert option on seek is not allowed.");return this.setNextParser("seek","",{length:t})}string(t,n){if(!n.zeroTerminated&&!n.length&&!n.greedy)throw new Error("One of length, zeroTerminated, or greedy must be defined for string.");if((n.zeroTerminated||n.length)&&n.greedy)throw new Error("greedy is mutually exclusive with length and zeroTerminated for string.");if(n.stripNull&&!(n.length||n.greedy))throw new Error("length or greedy must be defined if stripNull is enabled.");return n.encoding=n.encoding||"utf8",this.setNextParser("string",t,n)}buffer(t,n){if(!n.length&&!n.readUntil)throw new Error("length or readUntil must be defined for buffer.");return this.setNextParser("buffer",t,n)}wrapped(t,n){if(typeof n!="object"&&typeof t=="object"&&(n=t,t=""),!n||!n.wrapper||!n.type)throw new Error("Both wrapper and type must be defined for wrapped.");if(!n.length&&!n.readUntil)throw new Error("length or readUntil must be defined for wrapped.");return this.setNextParser("wrapper",t,n)}array(t,n){if(!n.readUntil&&!n.length&&!n.lengthInBytes)throw new Error("One of readUntil, length and lengthInBytes must be defined for array.");if(!n.type)throw new Error("type is required for array.");if(typeof n.type=="string"&&!rr.has(n.type)&&!(n.type in ir))throw new Error(`Array element type "${n.type}" is unkown.`);return this.setNextParser("array",t,n)}choice(t,n){if(typeof n!="object"&&typeof t=="object"&&(n=t,t=""),!n)throw new Error("tag and choices are are required for choice.");if(!n.tag)throw new Error("tag is requird for choice.");if(!n.choices)throw new Error("choices is required for choice.");for(const r in n.choices){const i=parseInt(r,10),a=n.choices[i];if(isNaN(i))throw new Error(`Choice key "${r}" is not a number.`);if(typeof a=="string"&&!rr.has(a)&&!(a in ir))throw new Error(`Choice type "${a}" is unkown.`)}return this.setNextParser("choice",t,n)}nest(t,n){if(typeof n!="object"&&typeof t=="object"&&(n=t,t=""),!n||!n.type)throw new Error("type is required for nest.");if(!(n.type instanceof sr)&&!rr.has(n.type))throw new Error("type must be a known parser name or a Parser object.");if(!(n.type instanceof sr)&&!t)throw new Error("type must be a Parser object if the variable name is omitted.");return this.setNextParser("nest",t,n)}pointer(t,n){if(!n.offset)throw new Error("offset is required for pointer.");if(!n.type)throw new Error("type is required for pointer.");if(typeof n.type=="string"&&!(n.type in ir)&&!rr.has(n.type))throw new Error(`Pointer type "${n.type}" is unkown.`);return this.setNextParser("pointer",t,n)}saveOffset(t,n={}){return this.setNextParser("saveOffset",t,n)}endianness(t){switch(t.toLowerCase()){case"little":this.endian="le";break;case"big":this.endian="be";break;default:throw new Error('endianness must be one of "little" or "big"')}return this}endianess(t){return this.endianness(t)}useContextVars(t=!0){return this.useContextVariables=t,this}create(t){if(!(t instanceof Function))throw new Error("Constructor must be a Function object.");return this.constructorFn=t,this}getContext(t){const n=new qY(t,this.useContextVariables);return n.pushCode("var dataView = new DataView(buffer.buffer, buffer.byteOffset, buffer.length);"),this.alias?(this.addAliasedCode(n),n.pushCode(`return ${Co+this.alias}(0).result;`)):this.addRawCode(n),n}getCode(){const t="imports";return this.getContext(t).code}addRawCode(t){t.pushCode("var offset = 0;"),t.pushCode(`var vars = ${this.constructorFn?"new constructorFn()":"{}"};`),t.pushCode("vars.$parent = null;"),t.pushCode("vars.$root = vars;"),this.generate(t),this.resolveReferences(t),t.pushCode("delete vars.$parent;"),t.pushCode("delete vars.$root;"),t.pushCode("return vars;")}addAliasedCode(t){return t.pushCode(`function ${Co+this.alias}(offset, context) {`),t.pushCode(`var vars = ${this.constructorFn?"new constructorFn()":"{}"};`),t.pushCode("var ctx = Object.assign({$parent: null, $root: vars}, context || {});"),t.pushCode("vars = Object.assign(vars, ctx);"),this.generate(t),t.markResolved(this.alias),this.resolveReferences(t),t.pushCode("Object.keys(ctx).forEach(function (item) { delete vars[item]; });"),t.pushCode("return { offset: offset, result: vars };"),t.pushCode("}"),t}resolveReferences(t){const n=t.getUnresolvedReferences();t.markRequested(n),n.forEach(r=>{var i;(i=rr.get(r))===null||i===void 0||i.addAliasedCode(t)})}compile(){const t="imports",n=this.getContext(t);this.compiled=new Function(t,"TextDecoder",`return function (buffer, constructorFn) { ${n.code} };`)(n.imports,TextDecoder)}sizeOf(){let t=NaN;if(Object.keys(ir).indexOf(this.type)>=0)t=ir[this.type];else if(this.type==="string"&&typeof this.options.length=="number")t=this.options.length;else if(this.type==="buffer"&&typeof this.options.length=="number")t=this.options.length;else if(this.type==="array"&&typeof this.options.length=="number"){let n=NaN;typeof this.options.type=="string"?n=ir[this.options.type]:this.options.type instanceof sr&&(n=this.options.type.sizeOf()),t=this.options.length*n}else this.type==="seek"?t=this.options.length:this.type==="nest"?t=this.options.type.sizeOf():this.type||(t=0);return this.next&&(t+=this.next.sizeOf()),t}parse(t){return this.compiled||this.compile(),this.compiled(t,this.constructorFn)}setNextParser(t,n,r){const i=new sr;return i.type=t,i.varName=n,i.options=r,i.endian=this.endian,this.head?this.head.next=i:this.next=i,this.head=i,this}generate(t){if(this.type){switch(this.type){case"uint8":case"uint16le":case"uint16be":case"uint32le":case"uint32be":case"int8":case"int16le":case"int16be":case"int32le":case"int32be":case"int64be":case"int64le":case"uint64be":case"uint64le":case"floatle":case"floatbe":case"doublele":case"doublebe":this.primitiveGenerateN(this.type,t);break;case"bit":this.generateBit(t);break;case"string":this.generateString(t);break;case"buffer":this.generateBuffer(t);break;case"seek":this.generateSeek(t);break;case"nest":this.generateNest(t);break;case"array":this.generateArray(t);break;case"choice":this.generateChoice(t);break;case"pointer":this.generatePointer(t);break;case"saveOffset":this.generateSaveOffset(t);break;case"wrapper":this.generateWrapper(t);break}this.type!=="bit"&&this.generateAssert(t)}const n=t.generateVariable(this.varName);return this.options.formatter&&this.type!=="bit"&&this.generateFormatter(t,n,this.options.formatter),this.generateNext(t)}generateAssert(t){if(!this.options.assert)return;const n=t.generateVariable(this.varName);switch(typeof this.options.assert){case"function":{const r=t.addImport(this.options.assert);t.pushCode(`if (!${r}.call(vars, ${n})) {`)}break;case"number":t.pushCode(`if (${this.options.assert} !== ${n}) {`);break;case"string":t.pushCode(`if (${JSON.stringify(this.options.assert)} !== ${n}) {`);break;default:throw new Error("assert option must be a string, number or a function.")}t.generateError(`"Assertion error: ${n} is " + ${JSON.stringify(this.options.assert.toString())}`),t.pushCode("}")}generateNext(t){return this.next&&(t=this.next.generate(t)),t}generateBit(t){const n=JSON.parse(JSON.stringify(this));if(n.options=this.options,n.generateAssert=this.generateAssert.bind(this),n.generateFormatter=this.generateFormatter.bind(this),n.varName=t.generateVariable(n.varName),t.bitFields.push(n),!this.next||this.next&&["bit","nest"].indexOf(this.next.type)<0){const r=t.generateTmpVariable();t.pushCode(`var ${r} = 0;`);const i=(u=0)=>{let f=0;for(let h=u;h<t.bitFields.length;h++){const d=t.bitFields[h].options.length;if(f+d>32)break;f+=d}return f},a=u=>(u<=8?(t.pushCode(`${r} = dataView.getUint8(offset);`),u=8):u<=16?(t.pushCode(`${r} = dataView.getUint16(offset);`),u=16):u<=24?(t.pushCode(`${r} = (dataView.getUint16(offset) << 8) | dataView.getUint8(offset + 2);`),u=24):(t.pushCode(`${r} = dataView.getUint32(offset);`),u=32),t.pushCode(`offset += ${u/8};`),u);let o=0;const s=this.endian==="be";let c=0,l=0;t.bitFields.forEach((u,f)=>{let h=u.options.length;if(h>l){if(l){const g=-1>>>32-l;t.pushCode(`${u.varName} = (${r} & 0x${g.toString(16)}) << ${h-l};`),h-=l}o=0,l=c=a(i(f)-l)}const d=s?c-o-h:o,p=-1>>>32-h;t.pushCode(`${u.varName} ${h<u.options.length?"|=":"="} ${r} >> ${d} & 0x${p.toString(16)};`),u.options.length===32&&t.pushCode(`${u.varName} >>>= 0`),u.options.assert&&u.generateAssert(t),u.options.formatter&&u.generateFormatter(t,u.varName,u.options.formatter),o+=h,l-=h}),t.bitFields=[]}}generateSeek(t){const n=t.generateOption(this.options.length);t.pushCode(`offset += ${n};`)}generateString(t){const n=t.generateVariable(this.varName),r=t.generateTmpVariable(),i=this.options.encoding,a=i.toLowerCase()==="hex",o='b => b.toString(16).padStart(2, "0")';if(this.options.length&&this.options.zeroTerminated){const s=this.options.length;t.pushCode(`var ${r} = offset;`),t.pushCode(`while(dataView.getUint8(offset++) !== 0 && offset - ${r} < ${s});`);const c=`offset - ${r} < ${s} ? offset - 1 : offset`;t.pushCode(a?`${n} = Array.from(buffer.subarray(${r}, ${c}), ${o}).join('');`:`${n} = new TextDecoder('${i}').decode(buffer.subarray(${r}, ${c}));`)}else if(this.options.length){const s=t.generateOption(this.options.length);t.pushCode(a?`${n} = Array.from(buffer.subarray(offset, offset + ${s}), ${o}).join('');`:`${n} = new TextDecoder('${i}').decode(buffer.subarray(offset, offset + ${s}));`),t.pushCode(`offset += ${s};`)}else this.options.zeroTerminated?(t.pushCode(`var ${r} = offset;`),t.pushCode("while(dataView.getUint8(offset++) !== 0);"),t.pushCode(a?`${n} = Array.from(buffer.subarray(${r}, offset - 1), ${o}).join('');`:`${n} = new TextDecoder('${i}').decode(buffer.subarray(${r}, offset - 1));`)):this.options.greedy&&(t.pushCode(`var ${r} = offset;`),t.pushCode("while(buffer.length > offset++);"),t.pushCode(a?`${n} = Array.from(buffer.subarray(${r}, offset), ${o}).join('');`:`${n} = new TextDecoder('${i}').decode(buffer.subarray(${r}, offset));`));this.options.stripNull&&t.pushCode(`${n} = ${n}.replace(/\\x00+$/g, '')`)}generateBuffer(t){const n=t.generateVariable(this.varName);if(typeof this.options.readUntil=="function"){const r=this.options.readUntil,i=t.generateTmpVariable(),a=t.generateTmpVariable();t.pushCode(`var ${i} = offset;`),t.pushCode(`var ${a} = 0;`),t.pushCode("while (offset < buffer.length) {"),t.pushCode(`${a} = dataView.getUint8(offset);`);const o=t.addImport(r);t.pushCode(`if (${o}.call(${t.generateVariable()}, ${a}, buffer.subarray(offset))) break;`),t.pushCode("offset += 1;"),t.pushCode("}"),t.pushCode(`${n} = buffer.subarray(${i}, offset);`)}else if(this.options.readUntil==="eof")t.pushCode(`${n} = buffer.subarray(offset);`);else{const r=t.generateOption(this.options.length);t.pushCode(`${n} = buffer.subarray(offset, offset + ${r});`),t.pushCode(`offset += ${r};`)}this.options.clone&&t.pushCode(`${n} = buffer.constructor.from(${n});`)}generateArray(t){const n=t.generateOption(this.options.length),r=t.generateOption(this.options.lengthInBytes),i=this.options.type,a=t.generateTmpVariable(),o=t.generateVariable(this.varName),s=t.generateTmpVariable(),c=this.options.key,l=typeof c=="string";if(l?t.pushCode(`${o} = {};`):t.pushCode(`${o} = [];`),typeof this.options.readUntil=="function"?t.pushCode("do {"):this.options.readUntil==="eof"?t.pushCode(`for (var ${a} = 0; offset < buffer.length; ${a}++) {`):r!==void 0?t.pushCode(`for (var ${a} = offset + ${r}; offset < ${a}; ) {`):t.pushCode(`for (var ${a} = ${n}; ${a} > 0; ${a}--) {`),typeof i=="string")if(rr.get(i)){const u=t.generateTmpVariable();if(t.pushCode(`var ${u} = ${Co+i}(offset, {`),t.useContextVariables){const f=t.generateVariable();t.pushCode(`$parent: ${f},`),t.pushCode(`$root: ${f}.$root,`),!this.options.readUntil&&r===void 0&&t.pushCode(`$index: ${n} - ${a},`)}t.pushCode("});"),t.pushCode(`var ${s} = ${u}.result; offset = ${u}.offset;`),i!==this.alias&&t.addReference(i)}else{const u=b0[i],f=y0[i];t.pushCode(`var ${s} = dataView.get${u}(offset, ${f});`),t.pushCode(`offset += ${ir[i]};`)}else if(i instanceof sr){t.pushCode(`var ${s} = {};`);const u=t.generateVariable();t.pushScope(s),t.useContextVariables&&(t.pushCode(`${s}.$parent = ${u};`),t.pushCode(`${s}.$root = ${u}.$root;`),!this.options.readUntil&&r===void 0&&t.pushCode(`${s}.$index = ${n} - ${a};`)),i.generate(t),t.useContextVariables&&(t.pushCode(`delete ${s}.$parent;`),t.pushCode(`delete ${s}.$root;`),t.pushCode(`delete ${s}.$index;`)),t.popScope()}if(l?t.pushCode(`${o}[${s}.${c}] = ${s};`):t.pushCode(`${o}.push(${s});`),t.pushCode("}"),typeof this.options.readUntil=="function"){const u=this.options.readUntil,f=t.addImport(u);t.pushCode(`while (!${f}.call(${t.generateVariable()}, ${s}, buffer.subarray(offset)));`)}}generateChoiceCase(t,n,r){if(typeof r=="string"){const i=t.generateVariable(this.varName);if(rr.has(r)){const a=t.generateTmpVariable();t.pushCode(`var ${a} = ${Co+r}(offset, {`),t.useContextVariables&&(t.pushCode(`$parent: ${i}.$parent,`),t.pushCode(`$root: ${i}.$root,`)),t.pushCode("});"),t.pushCode(`${i} = ${a}.result; offset = ${a}.offset;`),r!==this.alias&&t.addReference(r)}else{const a=b0[r],o=y0[r];t.pushCode(`${i} = dataView.get${a}(offset, ${o});`),t.pushCode(`offset += ${ir[r]}`)}}else r instanceof sr&&(t.pushPath(n),r.generate(t),t.popPath(n))}generateChoice(t){const n=t.generateOption(this.options.tag),r=t.generateVariable(this.varName);if(this.varName&&(t.pushCode(`${r} = {};`),t.useContextVariables)){const i=t.generateVariable();t.pushCode(`${r}.$parent = ${i};`),t.pushCode(`${r}.$root = ${i}.$root;`)}t.pushCode(`switch(${n}) {`);for(const i in this.options.choices){const a=parseInt(i,10),o=this.options.choices[a];t.pushCode(`case ${a}:`),this.generateChoiceCase(t,this.varName,o),t.pushCode("break;")}t.pushCode("default:"),this.options.defaultChoice?this.generateChoiceCase(t,this.varName,this.options.defaultChoice):t.generateError(`"Met undefined tag value " + ${n} + " at choice"`),t.pushCode("}"),this.varName&&t.useContextVariables&&(t.pushCode(`delete ${r}.$parent;`),t.pushCode(`delete ${r}.$root;`))}generateNest(t){const n=t.generateVariable(this.varName);if(this.options.type instanceof sr){if(this.varName&&(t.pushCode(`${n} = {};`),t.useContextVariables)){const r=t.generateVariable();t.pushCode(`${n}.$parent = ${r};`),t.pushCode(`${n}.$root = ${r}.$root;`)}t.pushPath(this.varName),this.options.type.generate(t),t.popPath(this.varName),this.varName&&t.useContextVariables&&t.useContextVariables&&(t.pushCode(`delete ${n}.$parent;`),t.pushCode(`delete ${n}.$root;`))}else if(rr.has(this.options.type)){const r=t.generateTmpVariable();if(t.pushCode(`var ${r} = ${Co+this.options.type}(offset, {`),t.useContextVariables){const i=t.generateVariable();t.pushCode(`$parent: ${i},`),t.pushCode(`$root: ${i}.$root,`)}t.pushCode("});"),t.pushCode(`${n} = ${r}.result; offset = ${r}.offset;`),this.options.type!==this.alias&&t.addReference(this.options.type)}}generateWrapper(t){const n=t.generateVariable(this.varName),r=t.generateTmpVariable();if(typeof this.options.readUntil=="function"){const c=this.options.readUntil,l=t.generateTmpVariable(),u=t.generateTmpVariable();t.pushCode(`var ${l} = offset;`),t.pushCode(`var ${u} = 0;`),t.pushCode("while (offset < buffer.length) {"),t.pushCode(`${u} = dataView.getUint8(offset);`);const f=t.addImport(c);t.pushCode(`if (${f}.call(${t.generateVariable()}, ${u}, buffer.subarray(offset))) break;`),t.pushCode("offset += 1;"),t.pushCode("}"),t.pushCode(`${r} = buffer.subarray(${l}, offset);`)}else if(this.options.readUntil==="eof")t.pushCode(`${r} = buffer.subarray(offset);`);else{const c=t.generateOption(this.options.length);t.pushCode(`${r} = buffer.subarray(offset, offset + ${c});`),t.pushCode(`offset += ${c};`)}this.options.clone&&t.pushCode(`${r} = buffer.constructor.from(${r});`);const i=t.generateTmpVariable(),a=t.generateTmpVariable(),o=t.generateTmpVariable(),s=t.addImport(this.options.wrapper);if(t.pushCode(`${r} = ${s}.call(this, ${r}).subarray(0);`),t.pushCode(`var ${i} = buffer;`),t.pushCode(`var ${a} = offset;`),t.pushCode(`var ${o} = dataView;`),t.pushCode(`buffer = ${r};`),t.pushCode("offset = 0;"),t.pushCode("dataView = new DataView(buffer.buffer, buffer.byteOffset, buffer.length);"),this.options.type instanceof sr)this.varName&&t.pushCode(`${n} = {};`),t.pushPath(this.varName),this.options.type.generate(t),t.popPath(this.varName);else if(rr.has(this.options.type)){const c=t.generateTmpVariable();t.pushCode(`var ${c} = ${Co+this.options.type}(0);`),t.pushCode(`${n} = ${c}.result;`),this.options.type!==this.alias&&t.addReference(this.options.type)}t.pushCode(`buffer = ${i};`),t.pushCode(`dataView = ${o};`),t.pushCode(`offset = ${a};`)}generateFormatter(t,n,r){if(typeof r=="function"){const i=t.addImport(r);t.pushCode(`${n} = ${i}.call(${t.generateVariable()}, ${n});`)}}generatePointer(t){const n=this.options.type,r=t.generateOption(this.options.offset),i=t.generateTmpVariable(),a=t.generateVariable(this.varName);if(t.pushCode(`var ${i} = offset;`),t.pushCode(`offset = ${r};`),this.options.type instanceof sr){if(t.pushCode(`${a} = {};`),t.useContextVariables){const o=t.generateVariable();t.pushCode(`${a}.$parent = ${o};`),t.pushCode(`${a}.$root = ${o}.$root;`)}t.pushPath(this.varName),this.options.type.generate(t),t.popPath(this.varName),t.useContextVariables&&(t.pushCode(`delete ${a}.$parent;`),t.pushCode(`delete ${a}.$root;`))}else if(rr.has(this.options.type)){const o=t.generateTmpVariable();if(t.pushCode(`var ${o} = ${Co+this.options.type}(offset, {`),t.useContextVariables){const s=t.generateVariable();t.pushCode(`$parent: ${s},`),t.pushCode(`$root: ${s}.$root,`)}t.pushCode("});"),t.pushCode(`${a} = ${o}.result; offset = 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Array(To+1);for(n=0,r=0;r<Ay-1;r++)for(ky[r]=n,e=0;e<1<<Cy[r];e++)Mu[n++]=r;for(Mu[n-1]=r,i=0,r=0;r<16;r++)for(_0[r]=i,e=0;e<1<<S0[r];e++)Pu[i++]=r;for(i>>=7;r<Gs;r++)for(_0[r]=i<<7,e=0;e<1<<S0[r]-7;e++)Pu[256+i++]=r;for(t=0;t<=To;t++)a[t]=0;for(e=0;e<=143;)ti[e*2+1]=8,e++,a[8]++;for(;e<=255;)ti[e*2+1]=9,e++,a[9]++;for(;e<=279;)ti[e*2+1]=7,e++,a[7]++;for(;e<=287;)ti[e*2+1]=8,e++,a[8]++;for(S5(ti,Bu+1,a),e=0;e<Gs;e++)Fu[e*2+1]=5,Fu[e*2]=E5(e,5);v5=new Ty(ti,Cy,Du+1,Bu,To),w5=new Ty(Fu,S0,0,Gs,To),x5=new Ty(new Array(0),wZ,0,Ey,vZ)},_5=e=>{let t;for(t=0;t<Bu;t++)e.dyn_ltree[t*2]=0;for(t=0;t<Gs;t++)e.dyn_dtree[t*2]=0;for(t=0;t<Ey;t++)e.bl_tree[t*2]=0;e.dyn_ltree[_y*2]=1,e.opt_len=e.static_len=0,e.sym_next=e.matches=0},C5=e=>{e.bi_valid>8?Ou(e,e.bi_buf):e.bi_valid>0&&(e.pending_buf[e.pending++]=e.bi_buf),e.bi_buf=0,e.bi_valid=0},k5=(e,t,n,r)=>{const i=t*2,a=n*2;return e[i]<e[a]||e[i]===e[a]&&r[t]<=r[n]},Ry=(e,t,n)=>{const r=e.heap[n];let 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o=e.heap[1],e.heap[1]=e.heap[e.heap_len--],Ry(e,n,1),s=e.heap[1],e.heap[--e.heap_max]=o,e.heap[--e.heap_max]=s,n[l*2]=n[o*2]+n[s*2],e.depth[l]=(e.depth[o]>=e.depth[s]?e.depth[o]:e.depth[s])+1,n[o*2+1]=n[s*2+1]=l,e.heap[1]=l++,Ry(e,n,1);while(e.heap_len>=2);e.heap[--e.heap_max]=e.heap[1],EZ(e,t),S5(n,c,e.bl_count)},I5=(e,t,n)=>{let r,i=-1,a,o=t[0*2+1],s=0,c=7,l=4;for(o===0&&(c=138,l=3),t[(n+1)*2+1]=65535,r=0;r<=n;r++)a=o,o=t[(r+1)*2+1],!(++s<c&&a===o)&&(s<l?e.bl_tree[a*2]+=s:a!==0?(a!==i&&e.bl_tree[a*2]++,e.bl_tree[g5*2]++):s<=10?e.bl_tree[m5*2]++:e.bl_tree[b5*2]++,s=0,i=a,o===0?(c=138,l=3):a===o?(c=6,l=3):(c=7,l=4))},R5=(e,t,n)=>{let r,i=-1,a,o=t[0*2+1],s=0,c=7,l=4;for(o===0&&(c=138,l=3),r=0;r<=n;r++)if(a=o,o=t[(r+1)*2+1],!(++s<c&&a===o)){if(s<l)do kr(e,a,e.bl_tree);while(--s!==0);else a!==0?(a!==i&&(kr(e,a,e.bl_tree),s--),kr(e,g5,e.bl_tree),cn(e,s-3,2)):s<=10?(kr(e,m5,e.bl_tree),cn(e,s-3,3)):(kr(e,b5,e.bl_tree),cn(e,s-11,7));s=0,i=a,o===0?(c=138,l=3):a===o?(c=6,l=3):(c=7,l=4)}},_Z=e=>{let t;for(I5(e,e.dyn_ltree,e.l_desc.max_code),I5(e,e.dyn_dtree,e.d_desc.max_code),Dy(e,e.bl_desc),t=Ey-1;t>=3&&e.bl_tree[y5[t]*2+1]===0;t--);return e.opt_len+=3*(t+1)+5+5+4,t},CZ=(e,t,n,r)=>{let i;for(cn(e,t-257,5),cn(e,n-1,5),cn(e,r-4,4),i=0;i<r;i++)cn(e,e.bl_tree[y5[i]*2+1],3);R5(e,e.dyn_ltree,t-1),R5(e,e.dyn_dtree,n-1)},kZ=e=>{let t=4093624447,n;for(n=0;n<=31;n++,t>>>=1)if(t&1&&e.dyn_ltree[n*2]!==0)return f5;if(e.dyn_ltree[9*2]!==0||e.dyn_ltree[10*2]!==0||e.dyn_ltree[13*2]!==0)return h5;for(n=32;n<Du;n++)if(e.dyn_ltree[n*2]!==0)return h5;return f5};let D5=!1;const TZ=e=>{D5||(SZ(),D5=!0),e.l_desc=new Iy(e.dyn_ltree,v5),e.d_desc=new Iy(e.dyn_dtree,w5),e.bl_desc=new Iy(e.bl_tree,x5),e.bi_buf=0,e.bi_valid=0,_5(e)},B5=(e,t,n,r)=>{cn(e,(gZ<<1)+(r?1:0),3),C5(e),Ou(e,n),Ou(e,~n),n&&e.pending_buf.set(e.window.subarray(t,t+n),e.pending),e.pending+=n},IZ=e=>{cn(e,d5<<1,3),kr(e,_y,ti),AZ(e)},RZ=(e,t,n,r)=>{let i,a,o=0;e.level>0?(e.strm.data_type===pZ&&(e.strm.data_type=kZ(e)),Dy(e,e.l_desc),Dy(e,e.d_desc),o=_Z(e),i=e.opt_len+3+7>>>3,a=e.static_len+3+7>>>3,a<=i&&(i=a)):i=a=n+5,n+4<=i&&t!==-1?B5(e,t,n,r):e.strategy===dZ||a===i?(cn(e,(d5<<1)+(r?1:0),3),T5(e,ti,Fu)):(cn(e,(mZ<<1)+(r?1:0),3),CZ(e,e.l_desc.max_code+1,e.d_desc.max_code+1,o+1),T5(e,e.dyn_ltree,e.dyn_dtree)),_5(e),r&&C5(e)},DZ=(e,t,n)=>(e.pending_buf[e.sym_buf+e.sym_next++]=t,e.pending_buf[e.sym_buf+e.sym_next++]=t>>8,e.pending_buf[e.sym_buf+e.sym_next++]=n,t===0?e.dyn_ltree[n*2]++:(e.matches++,t--,e.dyn_ltree[(Mu[n]+Du+1)*2]++,e.dyn_dtree[A5(t)*2]++),e.sym_next===e.sym_end);var BZ=TZ,FZ=B5,PZ=RZ,MZ=DZ,OZ=IZ,LZ={_tr_init:BZ,_tr_stored_block:FZ,_tr_flush_block:PZ,_tr_tally:MZ,_tr_align:OZ},Lu=(e,t,n,r)=>{let i=e&65535|0,a=e>>>16&65535|0,o=0;for(;n!==0;){o=n>2e3?2e3:n,n-=o;do i=i+t[r++]|0,a=a+i|0;while(--o);i%=65521,a%=65521}return i|a<<16|0};const NZ=()=>{let e,t=[];for(var n=0;n<256;n++){e=n;for(var r=0;r<8;r++)e=e&1?3988292384^e>>>1:e>>>1;t[n]=e}return t},zZ=new Uint32Array(NZ());var Tt=(e,t,n,r)=>{const i=zZ,a=r+n;e^=-1;for(let o=r;o<a;o++)e=e>>>8^i[(e^t[o])&255];return e^-1},Vs={2:"need dictionary",1:"stream end",0:"","-1":"file error","-2":"stream error","-3":"data error","-4":"insufficient memory","-5":"buffer error","-6":"incompatible version"},Nu={Z_NO_FLUSH:0,Z_PARTIAL_FLUSH:1,Z_SYNC_FLUSH:2,Z_FULL_FLUSH:3,Z_FINISH:4,Z_BLOCK:5,Z_TREES:6,Z_OK:0,Z_STREAM_END:1,Z_NEED_DICT:2,Z_ERRNO:-1,Z_STREAM_ERROR:-2,Z_DATA_ERROR:-3,Z_MEM_ERROR:-4,Z_BUF_ERROR:-5,Z_NO_COMPRESSION:0,Z_BEST_SPEED:1,Z_BEST_COMPRESSION:9,Z_DEFAULT_COMPRESSION:-1,Z_FILTERED:1,Z_HUFFMAN_ONLY:2,Z_RLE:3,Z_FIXED:4,Z_DEFAULT_STRATEGY:0,Z_BINARY:0,Z_TEXT:1,Z_UNKNOWN:2,Z_DEFLATED:8};const{_tr_init:UZ,_tr_stored_block:By,_tr_flush_block:$Z,_tr_tally:na,_tr_align:HZ}=LZ,{Z_NO_FLUSH:ra,Z_PARTIAL_FLUSH:GZ,Z_FULL_FLUSH:VZ,Z_FINISH:Bn,Z_BLOCK:F5,Z_OK:Mt,Z_STREAM_END:P5,Z_STREAM_ERROR:Tr,Z_DATA_ERROR:jZ,Z_BUF_ERROR:Fy,Z_DEFAULT_COMPRESSION:qZ,Z_FILTERED:WZ,Z_HUFFMAN_ONLY:C0,Z_RLE:YZ,Z_FIXED:ZZ,Z_DEFAULT_STRATEGY:QZ,Z_UNKNOWN:XZ,Z_DEFLATED:k0}=Nu,KZ=9,JZ=15,eQ=8,tQ=29,Py=256+1+tQ,nQ=30,rQ=19,iQ=2*Py+1,aQ=15,ye=3,ia=258,Ir=ia+ye+1,oQ=32,js=42,My=57,Oy=69,Ly=73,Ny=91,zy=103,Io=113,zu=666,Yt=1,qs=2,Ro=3,Ws=4,sQ=3,Do=(e,t)=>(e.msg=Vs[t],t),M5=e=>e*2-(e>4?9:0),aa=e=>{let t=e.length;for(;--t>=0;)e[t]=0},cQ=e=>{let t,n,r,i=e.w_size;t=e.hash_size,r=t;do n=e.head[--r],e.head[r]=n>=i?n-i:0;while(--t);t=i,r=t;do n=e.prev[--r],e.prev[r]=n>=i?n-i:0;while(--t)};let oa=(e,t,n)=>(t<<e.hash_shift^n)&e.hash_mask;const bn=e=>{const t=e.state;let n=t.pending;n>e.avail_out&&(n=e.avail_out),n!==0&&(e.output.set(t.pending_buf.subarray(t.pending_out,t.pending_out+n),e.next_out),e.next_out+=n,t.pending_out+=n,e.total_out+=n,e.avail_out-=n,t.pending-=n,t.pending===0&&(t.pending_out=0))},yn=(e,t)=>{$Z(e,e.block_start>=0?e.block_start:-1,e.strstart-e.block_start,t),e.block_start=e.strstart,bn(e.strm)},Ce=(e,t)=>{e.pending_buf[e.pending++]=t},Uu=(e,t)=>{e.pending_buf[e.pending++]=t>>>8&255,e.pending_buf[e.pending++]=t&255},Uy=(e,t,n,r)=>{let i=e.avail_in;return i>r&&(i=r),i===0?0:(e.avail_in-=i,t.set(e.input.subarray(e.next_in,e.next_in+i),n),e.state.wrap===1?e.adler=Lu(e.adler,t,i,n):e.state.wrap===2&&(e.adler=Tt(e.adler,t,i,n)),e.next_in+=i,e.total_in+=i,i)},O5=(e,t)=>{let n=e.max_chain_length,r=e.strstart,i,a,o=e.prev_length,s=e.nice_match;const c=e.strstart>e.w_size-Ir?e.strstart-(e.w_size-Ir):0,l=e.window,u=e.w_mask,f=e.prev,h=e.strstart+ia;let d=l[r+o-1],p=l[r+o];e.prev_length>=e.good_match&&(n>>=2),s>e.lookahead&&(s=e.lookahead);do if(i=t,!(l[i+o]!==p||l[i+o-1]!==d||l[i]!==l[r]||l[++i]!==l[r+1])){r+=2,i++;do;while(l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&l[++r]===l[++i]&&r<h);if(a=ia-(h-r),r=h-ia,a>o){if(e.match_start=t,o=a,a>=s)break;d=l[r+o-1],p=l[r+o]}}while((t=f[t&u])>c&&--n!==0);return o<=e.lookahead?o:e.lookahead},Ys=e=>{const t=e.w_size;let n,r,i;do{if(r=e.window_size-e.lookahead-e.strstart,e.strstart>=t+(t-Ir)&&(e.window.set(e.window.subarray(t,t+t-r),0),e.match_start-=t,e.strstart-=t,e.block_start-=t,e.insert>e.strstart&&(e.insert=e.strstart),cQ(e),r+=t),e.strm.avail_in===0)break;if(n=Uy(e.strm,e.window,e.strstart+e.lookahead,r),e.lookahead+=n,e.lookahead+e.insert>=ye)for(i=e.strstart-e.insert,e.ins_h=e.window[i],e.ins_h=oa(e,e.ins_h,e.window[i+1]);e.insert&&(e.ins_h=oa(e,e.ins_h,e.window[i+ye-1]),e.prev[i&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=i,i++,e.insert--,!(e.lookahead+e.insert<ye)););}while(e.lookahead<Ir&&e.strm.avail_in!==0)},L5=(e,t)=>{let n=e.pending_buf_size-5>e.w_size?e.w_size:e.pending_buf_size-5,r,i,a,o=0,s=e.strm.avail_in;do{if(r=65535,a=e.bi_valid+42>>3,e.strm.avail_out<a||(a=e.strm.avail_out-a,i=e.strstart-e.block_start,r>i+e.strm.avail_in&&(r=i+e.strm.avail_in),r>a&&(r=a),r<n&&(r===0&&t!==Bn||t===ra||r!==i+e.strm.avail_in)))break;o=t===Bn&&r===i+e.strm.avail_in?1:0,By(e,0,0,o),e.pending_buf[e.pending-4]=r,e.pending_buf[e.pending-3]=r>>8,e.pending_buf[e.pending-2]=~r,e.pending_buf[e.pending-1]=~r>>8,bn(e.strm),i&&(i>r&&(i=r),e.strm.output.set(e.window.subarray(e.block_start,e.block_start+i),e.strm.next_out),e.strm.next_out+=i,e.strm.avail_out-=i,e.strm.total_out+=i,e.block_start+=i,r-=i),r&&(Uy(e.strm,e.strm.output,e.strm.next_out,r),e.strm.next_out+=r,e.strm.avail_out-=r,e.strm.total_out+=r)}while(o===0);return s-=e.strm.avail_in,s&&(s>=e.w_size?(e.matches=2,e.window.set(e.strm.input.subarray(e.strm.next_in-e.w_size,e.strm.next_in),0),e.strstart=e.w_size,e.insert=e.strstart):(e.window_size-e.strstart<=s&&(e.strstart-=e.w_size,e.window.set(e.window.subarray(e.w_size,e.w_size+e.strstart),0),e.matches<2&&e.matches++,e.insert>e.strstart&&(e.insert=e.strstart)),e.window.set(e.strm.input.subarray(e.strm.next_in-s,e.strm.next_in),e.strstart),e.strstart+=s,e.insert+=s>e.w_size-e.insert?e.w_size-e.insert:s),e.block_start=e.strstart),e.high_water<e.strstart&&(e.high_water=e.strstart),o?Ws:t!==ra&&t!==Bn&&e.strm.avail_in===0&&e.strstart===e.block_start?qs:(a=e.window_size-e.strstart,e.strm.avail_in>a&&e.block_start>=e.w_size&&(e.block_start-=e.w_size,e.strstart-=e.w_size,e.window.set(e.window.subarray(e.w_size,e.w_size+e.strstart),0),e.matches<2&&e.matches++,a+=e.w_size,e.insert>e.strstart&&(e.insert=e.strstart)),a>e.strm.avail_in&&(a=e.strm.avail_in),a&&(Uy(e.strm,e.window,e.strstart,a),e.strstart+=a,e.insert+=a>e.w_size-e.insert?e.w_size-e.insert:a),e.high_water<e.strstart&&(e.high_water=e.strstart),a=e.bi_valid+42>>3,a=e.pending_buf_size-a>65535?65535:e.pending_buf_size-a,n=a>e.w_size?e.w_size:a,i=e.strstart-e.block_start,(i>=n||(i||t===Bn)&&t!==ra&&e.strm.avail_in===0&&i<=a)&&(r=i>a?a:i,o=t===Bn&&e.strm.avail_in===0&&r===i?1:0,By(e,e.block_start,r,o),e.block_start+=r,bn(e.strm)),o?Ro:Yt)},$y=(e,t)=>{let n,r;for(;;){if(e.lookahead<Ir){if(Ys(e),e.lookahead<Ir&&t===ra)return Yt;if(e.lookahead===0)break}if(n=0,e.lookahead>=ye&&(e.ins_h=oa(e,e.ins_h,e.window[e.strstart+ye-1]),n=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart),n!==0&&e.strstart-n<=e.w_size-Ir&&(e.match_length=O5(e,n)),e.match_length>=ye)if(r=na(e,e.strstart-e.match_start,e.match_length-ye),e.lookahead-=e.match_length,e.match_length<=e.max_lazy_match&&e.lookahead>=ye){e.match_length--;do e.strstart++,e.ins_h=oa(e,e.ins_h,e.window[e.strstart+ye-1]),n=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart;while(--e.match_length!==0);e.strstart++}else e.strstart+=e.match_length,e.match_length=0,e.ins_h=e.window[e.strstart],e.ins_h=oa(e,e.ins_h,e.window[e.strstart+1]);else r=na(e,0,e.window[e.strstart]),e.lookahead--,e.strstart++;if(r&&(yn(e,!1),e.strm.avail_out===0))return Yt}return e.insert=e.strstart<ye-1?e.strstart:ye-1,t===Bn?(yn(e,!0),e.strm.avail_out===0?Ro:Ws):e.sym_next&&(yn(e,!1),e.strm.avail_out===0)?Yt:qs},Zs=(e,t)=>{let n,r,i;for(;;){if(e.lookahead<Ir){if(Ys(e),e.lookahead<Ir&&t===ra)return Yt;if(e.lookahead===0)break}if(n=0,e.lookahead>=ye&&(e.ins_h=oa(e,e.ins_h,e.window[e.strstart+ye-1]),n=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart),e.prev_length=e.match_length,e.prev_match=e.match_start,e.match_length=ye-1,n!==0&&e.prev_length<e.max_lazy_match&&e.strstart-n<=e.w_size-Ir&&(e.match_length=O5(e,n),e.match_length<=5&&(e.strategy===WZ||e.match_length===ye&&e.strstart-e.match_start>4096)&&(e.match_length=ye-1)),e.prev_length>=ye&&e.match_length<=e.prev_length){i=e.strstart+e.lookahead-ye,r=na(e,e.strstart-1-e.prev_match,e.prev_length-ye),e.lookahead-=e.prev_length-1,e.prev_length-=2;do++e.strstart<=i&&(e.ins_h=oa(e,e.ins_h,e.window[e.strstart+ye-1]),n=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart);while(--e.prev_length!==0);if(e.match_available=0,e.match_length=ye-1,e.strstart++,r&&(yn(e,!1),e.strm.avail_out===0))return Yt}else if(e.match_available){if(r=na(e,0,e.window[e.strstart-1]),r&&yn(e,!1),e.strstart++,e.lookahead--,e.strm.avail_out===0)return Yt}else e.match_available=1,e.strstart++,e.lookahead--}return e.match_available&&(r=na(e,0,e.window[e.strstart-1]),e.match_available=0),e.insert=e.strstart<ye-1?e.strstart:ye-1,t===Bn?(yn(e,!0),e.strm.avail_out===0?Ro:Ws):e.sym_next&&(yn(e,!1),e.strm.avail_out===0)?Yt:qs},lQ=(e,t)=>{let n,r,i,a;const o=e.window;for(;;){if(e.lookahead<=ia){if(Ys(e),e.lookahead<=ia&&t===ra)return Yt;if(e.lookahead===0)break}if(e.match_length=0,e.lookahead>=ye&&e.strstart>0&&(i=e.strstart-1,r=o[i],r===o[++i]&&r===o[++i]&&r===o[++i])){a=e.strstart+ia;do;while(r===o[++i]&&r===o[++i]&&r===o[++i]&&r===o[++i]&&r===o[++i]&&r===o[++i]&&r===o[++i]&&r===o[++i]&&i<a);e.match_length=ia-(a-i),e.match_length>e.lookahead&&(e.match_length=e.lookahead)}if(e.match_length>=ye?(n=na(e,1,e.match_length-ye),e.lookahead-=e.match_length,e.strstart+=e.match_length,e.match_length=0):(n=na(e,0,e.window[e.strstart]),e.lookahead--,e.strstart++),n&&(yn(e,!1),e.strm.avail_out===0))return Yt}return e.insert=0,t===Bn?(yn(e,!0),e.strm.avail_out===0?Ro:Ws):e.sym_next&&(yn(e,!1),e.strm.avail_out===0)?Yt:qs},uQ=(e,t)=>{let n;for(;;){if(e.lookahead===0&&(Ys(e),e.lookahead===0)){if(t===ra)return Yt;break}if(e.match_length=0,n=na(e,0,e.window[e.strstart]),e.lookahead--,e.strstart++,n&&(yn(e,!1),e.strm.avail_out===0))return Yt}return e.insert=0,t===Bn?(yn(e,!0),e.strm.avail_out===0?Ro:Ws):e.sym_next&&(yn(e,!1),e.strm.avail_out===0)?Yt:qs};function Rr(e,t,n,r,i){this.good_length=e,this.max_lazy=t,this.nice_length=n,this.max_chain=r,this.func=i}const $u=[new Rr(0,0,0,0,L5),new Rr(4,4,8,4,$y),new Rr(4,5,16,8,$y),new Rr(4,6,32,32,$y),new Rr(4,4,16,16,Zs),new Rr(8,16,32,32,Zs),new Rr(8,16,128,128,Zs),new Rr(8,32,128,256,Zs),new Rr(32,128,258,1024,Zs),new Rr(32,258,258,4096,Zs)],fQ=e=>{e.window_size=2*e.w_size,aa(e.head),e.max_lazy_match=$u[e.level].max_lazy,e.good_match=$u[e.level].good_length,e.nice_match=$u[e.level].nice_length,e.max_chain_length=$u[e.level].max_chain,e.strstart=0,e.block_start=0,e.lookahead=0,e.insert=0,e.match_length=e.prev_length=ye-1,e.match_available=0,e.ins_h=0};function hQ(){this.strm=null,this.status=0,this.pending_buf=null,this.pending_buf_size=0,this.pending_out=0,this.pending=0,this.wrap=0,this.gzhead=null,this.gzindex=0,this.method=k0,this.last_flush=-1,this.w_size=0,this.w_bits=0,this.w_mask=0,this.window=null,this.window_size=0,this.prev=null,this.head=null,this.ins_h=0,this.hash_size=0,this.hash_bits=0,this.hash_mask=0,this.hash_shift=0,this.block_start=0,this.match_length=0,this.prev_match=0,this.match_available=0,this.strstart=0,this.match_start=0,this.lookahead=0,this.prev_length=0,this.max_chain_length=0,this.max_lazy_match=0,this.level=0,this.strategy=0,this.good_match=0,this.nice_match=0,this.dyn_ltree=new Uint16Array(iQ*2),this.dyn_dtree=new Uint16Array((2*nQ+1)*2),this.bl_tree=new Uint16Array((2*rQ+1)*2),aa(this.dyn_ltree),aa(this.dyn_dtree),aa(this.bl_tree),this.l_desc=null,this.d_desc=null,this.bl_desc=null,this.bl_count=new Uint16Array(aQ+1),this.heap=new 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s=new hQ;return e.state=s,s.strm=e,s.status=js,s.wrap=o,s.gzhead=null,s.w_bits=r,s.w_size=1<<s.w_bits,s.w_mask=s.w_size-1,s.hash_bits=i+7,s.hash_size=1<<s.hash_bits,s.hash_mask=s.hash_size-1,s.hash_shift=~~((s.hash_bits+ye-1)/ye),s.window=new Uint8Array(s.w_size*2),s.head=new Uint16Array(s.hash_size),s.prev=new Uint16Array(s.w_size),s.lit_bufsize=1<<i+6,s.pending_buf_size=s.lit_bufsize*4,s.pending_buf=new Uint8Array(s.pending_buf_size),s.sym_buf=s.lit_bufsize,s.sym_end=(s.lit_bufsize-1)*3,s.level=t,s.strategy=a,s.method=n,z5(e)},pQ=(e,t)=>U5(e,t,k0,JZ,eQ,QZ),gQ=(e,t)=>{if(Hu(e)||t>F5||t<0)return e?Do(e,Tr):Tr;const n=e.state;if(!e.output||e.avail_in!==0&&!e.input||n.status===zu&&t!==Bn)return Do(e,e.avail_out===0?Fy:Tr);const r=n.last_flush;if(n.last_flush=t,n.pending!==0){if(bn(e),e.avail_out===0)return n.last_flush=-1,Mt}else if(e.avail_in===0&&M5(t)<=M5(r)&&t!==Bn)return Do(e,Fy);if(n.status===zu&&e.avail_in!==0)return Do(e,Fy);if(n.status===js&&n.wrap===0&&(n.status=Io),n.status===js){let i=k0+(n.w_bits-8<<4)<<8,a=-1;if(n.strategy>=C0||n.level<2?a=0:n.level<6?a=1:n.level===6?a=2:a=3,i|=a<<6,n.strstart!==0&&(i|=oQ),i+=31-i%31,Uu(n,i),n.strstart!==0&&(Uu(n,e.adler>>>16),Uu(n,e.adler&65535)),e.adler=1,n.status=Io,bn(e),n.pending!==0)return n.last_flush=-1,Mt}if(n.status===My){if(e.adler=0,Ce(n,31),Ce(n,139),Ce(n,8),n.gzhead)Ce(n,(n.gzhead.text?1:0)+(n.gzhead.hcrc?2:0)+(n.gzhead.extra?4:0)+(n.gzhead.name?8:0)+(n.gzhead.comment?16:0)),Ce(n,n.gzhead.time&255),Ce(n,n.gzhead.time>>8&255),Ce(n,n.gzhead.time>>16&255),Ce(n,n.gzhead.time>>24&255),Ce(n,n.level===9?2:n.strategy>=C0||n.level<2?4:0),Ce(n,n.gzhead.os&255),n.gzhead.extra&&n.gzhead.extra.length&&(Ce(n,n.gzhead.extra.length&255),Ce(n,n.gzhead.extra.length>>8&255)),n.gzhead.hcrc&&(e.adler=Tt(e.adler,n.pending_buf,n.pending,0)),n.gzindex=0,n.status=Oy;else if(Ce(n,0),Ce(n,0),Ce(n,0),Ce(n,0),Ce(n,0),Ce(n,n.level===9?2:n.strategy>=C0||n.level<2?4:0),Ce(n,sQ),n.status=Io,bn(e),n.pending!==0)return n.last_flush=-1,Mt}if(n.status===Oy){if(n.gzhead.extra){let i=n.pending,a=(n.gzhead.extra.length&65535)-n.gzindex;for(;n.pending+a>n.pending_buf_size;){let s=n.pending_buf_size-n.pending;if(n.pending_buf.set(n.gzhead.extra.subarray(n.gzindex,n.gzindex+s),n.pending),n.pending=n.pending_buf_size,n.gzhead.hcrc&&n.pending>i&&(e.adler=Tt(e.adler,n.pending_buf,n.pending-i,i)),n.gzindex+=s,bn(e),n.pending!==0)return n.last_flush=-1,Mt;i=0,a-=s}let o=new Uint8Array(n.gzhead.extra);n.pending_buf.set(o.subarray(n.gzindex,n.gzindex+a),n.pending),n.pending+=a,n.gzhead.hcrc&&n.pending>i&&(e.adler=Tt(e.adler,n.pending_buf,n.pending-i,i)),n.gzindex=0}n.status=Ly}if(n.status===Ly){if(n.gzhead.name){let i=n.pending,a;do{if(n.pending===n.pending_buf_size){if(n.gzhead.hcrc&&n.pending>i&&(e.adler=Tt(e.adler,n.pending_buf,n.pending-i,i)),bn(e),n.pending!==0)return n.last_flush=-1,Mt;i=0}n.gzindex<n.gzhead.name.length?a=n.gzhead.name.charCodeAt(n.gzindex++)&255:a=0,Ce(n,a)}while(a!==0);n.gzhead.hcrc&&n.pending>i&&(e.adler=Tt(e.adler,n.pending_buf,n.pending-i,i)),n.gzindex=0}n.status=Ny}if(n.status===Ny){if(n.gzhead.comment){let i=n.pending,a;do{if(n.pending===n.pending_buf_size){if(n.gzhead.hcrc&&n.pending>i&&(e.adler=Tt(e.adler,n.pending_buf,n.pending-i,i)),bn(e),n.pending!==0)return n.last_flush=-1,Mt;i=0}n.gzindex<n.gzhead.comment.length?a=n.gzhead.comment.charCodeAt(n.gzindex++)&255:a=0,Ce(n,a)}while(a!==0);n.gzhead.hcrc&&n.pending>i&&(e.adler=Tt(e.adler,n.pending_buf,n.pending-i,i))}n.status=zy}if(n.status===zy){if(n.gzhead.hcrc){if(n.pending+2>n.pending_buf_size&&(bn(e),n.pending!==0))return n.last_flush=-1,Mt;Ce(n,e.adler&255),Ce(n,e.adler>>8&255),e.adler=0}if(n.status=Io,bn(e),n.pending!==0)return n.last_flush=-1,Mt}if(e.avail_in!==0||n.lookahead!==0||t!==ra&&n.status!==zu){let i=n.level===0?L5(n,t):n.strategy===C0?uQ(n,t):n.strategy===YZ?lQ(n,t):$u[n.level].func(n,t);if((i===Ro||i===Ws)&&(n.status=zu),i===Yt||i===Ro)return e.avail_out===0&&(n.last_flush=-1),Mt;if(i===qs&&(t===GZ?HZ(n):t!==F5&&(By(n,0,0,!1),t===VZ&&(aa(n.head),n.lookahead===0&&(n.strstart=0,n.block_start=0,n.insert=0))),bn(e),e.avail_out===0))return n.last_flush=-1,Mt}return t!==Bn?Mt:n.wrap<=0?P5:(n.wrap===2?(Ce(n,e.adler&255),Ce(n,e.adler>>8&255),Ce(n,e.adler>>16&255),Ce(n,e.adler>>24&255),Ce(n,e.total_in&255),Ce(n,e.total_in>>8&255),Ce(n,e.total_in>>16&255),Ce(n,e.total_in>>24&255)):(Uu(n,e.adler>>>16),Uu(n,e.adler&65535)),bn(e),n.wrap>0&&(n.wrap=-n.wrap),n.pending!==0?Mt:P5)},mQ=e=>{if(Hu(e))return Tr;const t=e.state.status;return e.state=null,t===Io?Do(e,jZ):Mt},bQ=(e,t)=>{let n=t.length;if(Hu(e))return Tr;const r=e.state,i=r.wrap;if(i===2||i===1&&r.status!==js||r.lookahead)return 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n=Gu.deflateInit2(this.strm,t.level,t.method,t.windowBits,t.memLevel,t.strategy);if(n!==I0)throw new Error(Vs[n]);if(t.header&&Gu.deflateSetHeader(this.strm,t.header),t.dictionary){let r;if(typeof t.dictionary=="string"?r=ju.string2buf(t.dictionary):G5.call(t.dictionary)==="[object ArrayBuffer]"?r=new Uint8Array(t.dictionary):r=t.dictionary,n=Gu.deflateSetDictionary(this.strm,r),n!==I0)throw new Error(Vs[n]);this._dict_set=!0}}Hy.prototype.push=function(e,t){const n=this.strm,r=this.options.chunkSize;let i,a;if(this.ended)return!1;for(t===~~t?a=t:a=t===!0?NQ:MQ,typeof e=="string"?n.input=ju.string2buf(e):G5.call(e)==="[object ArrayBuffer]"?n.input=new Uint8Array(e):n.input=e,n.next_in=0,n.avail_in=n.input.length;;){if(n.avail_out===0&&(n.output=new Uint8Array(r),n.next_out=0,n.avail_out=r),(a===OQ||a===LQ)&&n.avail_out<=6){this.onData(n.output.subarray(0,n.next_out)),n.avail_out=0;continue}if(i=Gu.deflate(n,a),i===zQ)return n.next_out>0&&this.onData(n.output.subarray(0,n.next_out)),i=Gu.deflateEnd(this.strm),this.onEnd(i),this.ended=!0,i===I0;if(n.avail_out===0){this.onData(n.output);continue}if(a>0&&n.next_out>0){this.onData(n.output.subarray(0,n.next_out)),n.avail_out=0;continue}if(n.avail_in===0)break}return!0},Hy.prototype.onData=function(e){this.chunks.push(e)},Hy.prototype.onEnd=function(e){e===I0&&(this.result=T0.flattenChunks(this.chunks)),this.chunks=[],this.err=e,this.msg=this.strm.msg};const R0=16209,GQ=16191;var VQ=function(t,n){let r,i,a,o,s,c,l,u,f,h,d,p,g,b,y,w,A,x,C,_,I,D,M,G;const O=t.state;r=t.next_in,M=t.input,i=r+(t.avail_in-5),a=t.next_out,G=t.output,o=a-(n-t.avail_out),s=a+(t.avail_out-257),c=O.dmax,l=O.wsize,u=O.whave,f=O.wnext,h=O.window,d=O.hold,p=O.bits,g=O.lencode,b=O.distcode,y=(1<<O.lenbits)-1,w=(1<<O.distbits)-1;e:do{p<15&&(d+=M[r++]<<p,p+=8,d+=M[r++]<<p,p+=8),A=g[d&y];t:for(;;){if(x=A>>>24,d>>>=x,p-=x,x=A>>>16&255,x===0)G[a++]=A&65535;else if(x&16){C=A&65535,x&=15,x&&(p<x&&(d+=M[r++]<<p,p+=8),C+=d&(1<<x)-1,d>>>=x,p-=x),p<15&&(d+=M[r++]<<p,p+=8,d+=M[r++]<<p,p+=8),A=b[d&w];n:for(;;){if(x=A>>>24,d>>>=x,p-=x,x=A>>>16&255,x&16){if(_=A&65535,x&=15,p<x&&(d+=M[r++]<<p,p+=8,p<x&&(d+=M[r++]<<p,p+=8)),_+=d&(1<<x)-1,_>c){t.msg="invalid distance too far back",O.mode=R0;break e}if(d>>>=x,p-=x,x=a-o,_>x){if(x=_-x,x>u&&O.sane){t.msg="invalid distance too far back",O.mode=R0;break e}if(I=0,D=h,f===0){if(I+=l-x,x<C){C-=x;do G[a++]=h[I++];while(--x);I=a-_,D=G}}else if(f<x){if(I+=l+f-x,x-=f,x<C){C-=x;do G[a++]=h[I++];while(--x);if(I=0,f<C){x=f,C-=x;do G[a++]=h[I++];while(--x);I=a-_,D=G}}}else if(I+=f-x,x<C){C-=x;do G[a++]=h[I++];while(--x);I=a-_,D=G}for(;C>2;)G[a++]=D[I++],G[a++]=D[I++],G[a++]=D[I++],C-=3;C&&(G[a++]=D[I++],C>1&&(G[a++]=D[I++]))}else{I=a-_;do G[a++]=G[I++],G[a++]=G[I++],G[a++]=G[I++],C-=3;while(C>2);C&&(G[a++]=G[I++],C>1&&(G[a++]=G[I++]))}}else if(x&64){t.msg="invalid distance code",O.mode=R0;break e}else{A=b[(A&65535)+(d&(1<<x)-1)];continue n}break}}else if(x&64)if(x&32){O.mode=GQ;break e}else{t.msg="invalid literal/length code",O.mode=R0;break e}else{A=g[(A&65535)+(d&(1<<x)-1)];continue t}break}}while(r<i&&a<s);C=p>>3,r-=C,p-=C<<3,d&=(1<<p)-1,t.next_in=r,t.next_out=a,t.avail_in=r<i?5+(i-r):5-(r-i),t.avail_out=a<s?257+(s-a):257-(a-s),O.hold=d,O.bits=p};const Qs=15,V5=852,j5=592,q5=0,Gy=1,W5=2,jQ=new Uint16Array([3,4,5,6,7,8,9,10,11,13,15,17,19,23,27,31,35,43,51,59,67,83,99,115,131,163,195,227,258,0,0]),qQ=new Uint8Array([16,16,16,16,16,16,16,16,17,17,17,17,18,18,18,18,19,19,19,19,20,20,20,20,21,21,21,21,16,72,78]),WQ=new Uint16Array([1,2,3,4,5,7,9,13,17,25,33,49,65,97,129,193,257,385,513,769,1025,1537,2049,3073,4097,6145,8193,12289,16385,24577,0,0]),YQ=new Uint8Array([16,16,16,16,17,17,18,18,19,19,20,20,21,21,22,22,23,23,24,24,25,25,26,26,27,27,28,28,29,29,64,64]);var qu=(e,t,n,r,i,a,o,s)=>{const c=s.bits;let l=0,u=0,f=0,h=0,d=0,p=0,g=0,b=0,y=0,w=0,A,x,C,_,I,D=null,M;const G=new Uint16Array(Qs+1),O=new Uint16Array(Qs+1);let ae=null,se,ve,Pe;for(l=0;l<=Qs;l++)G[l]=0;for(u=0;u<r;u++)G[t[n+u]]++;for(d=c,h=Qs;h>=1&&G[h]===0;h--);if(d>h&&(d=h),h===0)return i[a++]=1<<24|64<<16|0,i[a++]=1<<24|64<<16|0,s.bits=1,0;for(f=1;f<h&&G[f]===0;f++);for(d<f&&(d=f),b=1,l=1;l<=Qs;l++)if(b<<=1,b-=G[l],b<0)return-1;if(b>0&&(e===q5||h!==1))return-1;for(O[1]=0,l=1;l<Qs;l++)O[l+1]=O[l]+G[l];for(u=0;u<r;u++)t[n+u]!==0&&(o[O[t[n+u]]++]=u);if(e===q5?(D=ae=o,M=20):e===Gy?(D=jQ,ae=qQ,M=257):(D=WQ,ae=YQ,M=0),w=0,u=0,l=f,I=a,p=d,g=0,C=-1,y=1<<d,_=y-1,e===Gy&&y>V5||e===W5&&y>j5)return 1;for(;;){se=l-g,o[u]+1<M?(ve=0,Pe=o[u]):o[u]>=M?(ve=ae[o[u]-M],Pe=D[o[u]-M]):(ve=32+64,Pe=0),A=1<<l-g,x=1<<p,f=x;do x-=A,i[I+(w>>g)+x]=se<<24|ve<<16|Pe|0;while(x!==0);for(A=1<<l-1;w&A;)A>>=1;if(A!==0?(w&=A-1,w+=A):w=0,u++,--G[l]===0){if(l===h)break;l=t[n+o[u]]}if(l>d&&(w&_)!==C){for(g===0&&(g=d),I+=f,p=l-g,b=1<<p;p+g<h&&(b-=G[p+g],!(b<=0));)p++,b<<=1;if(y+=1<<p,e===Gy&&y>V5||e===W5&&y>j5)return 1;C=w&_,i[C]=d<<24|p<<16|I-a|0}}return w!==0&&(i[I+w]=l-g<<24|64<<16|0),s.bits=d,0};const ZQ=0,Y5=1,Z5=2,{Z_FINISH:Q5,Z_BLOCK:QQ,Z_TREES:D0,Z_OK:Bo,Z_STREAM_END:XQ,Z_NEED_DICT:KQ,Z_STREAM_ERROR:Fn,Z_DATA_ERROR:X5,Z_MEM_ERROR:K5,Z_BUF_ERROR:JQ,Z_DEFLATED:J5}=Nu,B0=16180,e8=16181,t8=16182,n8=16183,r8=16184,i8=16185,a8=16186,o8=16187,s8=16188,c8=16189,F0=16190,ni=16191,Vy=16192,l8=16193,jy=16194,u8=16195,f8=16196,h8=16197,d8=16198,P0=16199,M0=16200,p8=16201,g8=16202,m8=16203,b8=16204,y8=16205,qy=16206,v8=16207,w8=16208,Je=16209,x8=16210,A8=16211,eX=852,tX=592,nX=15,E8=e=>(e>>>24&255)+(e>>>8&65280)+((e&65280)<<8)+((e&255)<<24);function rX(){this.strm=null,this.mode=0,this.last=!1,this.wrap=0,this.havedict=!1,this.flags=0,this.dmax=0,this.check=0,this.total=0,this.head=null,this.wbits=0,this.wsize=0,this.whave=0,this.wnext=0,this.window=null,this.hold=0,this.bits=0,this.length=0,this.offset=0,this.extra=0,this.lencode=null,this.distcode=null,this.lenbits=0,this.distbits=0,this.ncode=0,this.nlen=0,this.ndist=0,this.have=0,this.next=null,this.lens=new Uint16Array(320),this.work=new Uint16Array(288),this.lendyn=null,this.distdyn=null,this.sane=0,this.back=0,this.was=0}const Fo=e=>{if(!e)return 1;const t=e.state;return!t||t.strm!==e||t.mode<B0||t.mode>A8?1:0},S8=e=>{if(Fo(e))return Fn;const t=e.state;return e.total_in=e.total_out=t.total=0,e.msg="",t.wrap&&(e.adler=t.wrap&1),t.mode=B0,t.last=0,t.havedict=0,t.flags=-1,t.dmax=32768,t.head=null,t.hold=0,t.bits=0,t.lencode=t.lendyn=new Int32Array(eX),t.distcode=t.distdyn=new Int32Array(tX),t.sane=1,t.back=-1,Bo},_8=e=>{if(Fo(e))return Fn;const t=e.state;return t.wsize=0,t.whave=0,t.wnext=0,S8(e)},C8=(e,t)=>{let n;if(Fo(e))return Fn;const r=e.state;return t<0?(n=0,t=-t):(n=(t>>4)+5,t<48&&(t&=15)),t&&(t<8||t>15)?Fn:(r.window!==null&&r.wbits!==t&&(r.window=null),r.wrap=n,r.wbits=t,_8(e))},k8=(e,t)=>{if(!e)return Fn;const n=new rX;e.state=n,n.strm=e,n.window=null,n.mode=B0;const r=C8(e,t);return r!==Bo&&(e.state=null),r},iX=e=>k8(e,nX);let T8=!0,Wy,Yy;const aX=e=>{if(T8){Wy=new Int32Array(512),Yy=new Int32Array(32);let t=0;for(;t<144;)e.lens[t++]=8;for(;t<256;)e.lens[t++]=9;for(;t<280;)e.lens[t++]=7;for(;t<288;)e.lens[t++]=8;for(qu(Y5,e.lens,0,288,Wy,0,e.work,{bits:9}),t=0;t<32;)e.lens[t++]=5;qu(Z5,e.lens,0,32,Yy,0,e.work,{bits:5}),T8=!1}e.lencode=Wy,e.lenbits=9,e.distcode=Yy,e.distbits=5},I8=(e,t,n,r)=>{let i;const a=e.state;return a.window===null&&(a.wsize=1<<a.wbits,a.wnext=0,a.whave=0,a.window=new Uint8Array(a.wsize)),r>=a.wsize?(a.window.set(t.subarray(n-a.wsize,n),0),a.wnext=0,a.whave=a.wsize):(i=a.wsize-a.wnext,i>r&&(i=r),a.window.set(t.subarray(n-r,n-r+i),a.wnext),r-=i,r?(a.window.set(t.subarray(n-r,n),0),a.wnext=r,a.whave=a.wsize):(a.wnext+=i,a.wnext===a.wsize&&(a.wnext=0),a.whave<a.wsize&&(a.whave+=i))),0},oX=(e,t)=>{let n,r,i,a,o,s,c,l,u,f,h,d,p,g,b=0,y,w,A,x,C,_,I,D;const M=new Uint8Array(4);let G,O;const ae=new Uint8Array([16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15]);if(Fo(e)||!e.output||!e.input&&e.avail_in!==0)return Fn;n=e.state,n.mode===ni&&(n.mode=Vy),o=e.next_out,i=e.output,c=e.avail_out,a=e.next_in,r=e.input,s=e.avail_in,l=n.hold,u=n.bits,f=s,h=c,D=Bo;e:for(;;)switch(n.mode){case B0:if(n.wrap===0){n.mode=Vy;break}for(;u<16;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(n.wrap&2&&l===35615){n.wbits===0&&(n.wbits=15),n.check=0,M[0]=l&255,M[1]=l>>>8&255,n.check=Tt(n.check,M,2,0),l=0,u=0,n.mode=e8;break}if(n.head&&(n.head.done=!1),!(n.wrap&1)||(((l&255)<<8)+(l>>8))%31){e.msg="incorrect header check",n.mode=Je;break}if((l&15)!==J5){e.msg="unknown compression method",n.mode=Je;break}if(l>>>=4,u-=4,I=(l&15)+8,n.wbits===0&&(n.wbits=I),I>15||I>n.wbits){e.msg="invalid window size",n.mode=Je;break}n.dmax=1<<n.wbits,n.flags=0,e.adler=n.check=1,n.mode=l&512?c8:ni,l=0,u=0;break;case e8:for(;u<16;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(n.flags=l,(n.flags&255)!==J5){e.msg="unknown compression method",n.mode=Je;break}if(n.flags&57344){e.msg="unknown header flags set",n.mode=Je;break}n.head&&(n.head.text=l>>8&1),n.flags&512&&n.wrap&4&&(M[0]=l&255,M[1]=l>>>8&255,n.check=Tt(n.check,M,2,0)),l=0,u=0,n.mode=t8;case t8:for(;u<32;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}n.head&&(n.head.time=l),n.flags&512&&n.wrap&4&&(M[0]=l&255,M[1]=l>>>8&255,M[2]=l>>>16&255,M[3]=l>>>24&255,n.check=Tt(n.check,M,4,0)),l=0,u=0,n.mode=n8;case n8:for(;u<16;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}n.head&&(n.head.xflags=l&255,n.head.os=l>>8),n.flags&512&&n.wrap&4&&(M[0]=l&255,M[1]=l>>>8&255,n.check=Tt(n.check,M,2,0)),l=0,u=0,n.mode=r8;case r8:if(n.flags&1024){for(;u<16;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}n.length=l,n.head&&(n.head.extra_len=l),n.flags&512&&n.wrap&4&&(M[0]=l&255,M[1]=l>>>8&255,n.check=Tt(n.check,M,2,0)),l=0,u=0}else n.head&&(n.head.extra=null);n.mode=i8;case i8:if(n.flags&1024&&(d=n.length,d>s&&(d=s),d&&(n.head&&(I=n.head.extra_len-n.length,n.head.extra||(n.head.extra=new Uint8Array(n.head.extra_len)),n.head.extra.set(r.subarray(a,a+d),I)),n.flags&512&&n.wrap&4&&(n.check=Tt(n.check,r,d,a)),s-=d,a+=d,n.length-=d),n.length))break e;n.length=0,n.mode=a8;case a8:if(n.flags&2048){if(s===0)break e;d=0;do I=r[a+d++],n.head&&I&&n.length<65536&&(n.head.name+=String.fromCharCode(I));while(I&&d<s);if(n.flags&512&&n.wrap&4&&(n.check=Tt(n.check,r,d,a)),s-=d,a+=d,I)break e}else n.head&&(n.head.name=null);n.length=0,n.mode=o8;case o8:if(n.flags&4096){if(s===0)break e;d=0;do I=r[a+d++],n.head&&I&&n.length<65536&&(n.head.comment+=String.fromCharCode(I));while(I&&d<s);if(n.flags&512&&n.wrap&4&&(n.check=Tt(n.check,r,d,a)),s-=d,a+=d,I)break e}else n.head&&(n.head.comment=null);n.mode=s8;case s8:if(n.flags&512){for(;u<16;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(n.wrap&4&&l!==(n.check&65535)){e.msg="header crc mismatch",n.mode=Je;break}l=0,u=0}n.head&&(n.head.hcrc=n.flags>>9&1,n.head.done=!0),e.adler=n.check=0,n.mode=ni;break;case c8:for(;u<32;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}e.adler=n.check=E8(l),l=0,u=0,n.mode=F0;case F0:if(n.havedict===0)return e.next_out=o,e.avail_out=c,e.next_in=a,e.avail_in=s,n.hold=l,n.bits=u,KQ;e.adler=n.check=1,n.mode=ni;case ni:if(t===QQ||t===D0)break e;case Vy:if(n.last){l>>>=u&7,u-=u&7,n.mode=qy;break}for(;u<3;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}switch(n.last=l&1,l>>>=1,u-=1,l&3){case 0:n.mode=l8;break;case 1:if(aX(n),n.mode=P0,t===D0){l>>>=2,u-=2;break e}break;case 2:n.mode=f8;break;case 3:e.msg="invalid block type",n.mode=Je}l>>>=2,u-=2;break;case l8:for(l>>>=u&7,u-=u&7;u<32;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if((l&65535)!==(l>>>16^65535)){e.msg="invalid stored block lengths",n.mode=Je;break}if(n.length=l&65535,l=0,u=0,n.mode=jy,t===D0)break e;case jy:n.mode=u8;case u8:if(d=n.length,d){if(d>s&&(d=s),d>c&&(d=c),d===0)break e;i.set(r.subarray(a,a+d),o),s-=d,a+=d,c-=d,o+=d,n.length-=d;break}n.mode=ni;break;case f8:for(;u<14;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(n.nlen=(l&31)+257,l>>>=5,u-=5,n.ndist=(l&31)+1,l>>>=5,u-=5,n.ncode=(l&15)+4,l>>>=4,u-=4,n.nlen>286||n.ndist>30){e.msg="too many length or distance symbols",n.mode=Je;break}n.have=0,n.mode=h8;case h8:for(;n.have<n.ncode;){for(;u<3;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}n.lens[ae[n.have++]]=l&7,l>>>=3,u-=3}for(;n.have<19;)n.lens[ae[n.have++]]=0;if(n.lencode=n.lendyn,n.lenbits=7,G={bits:n.lenbits},D=qu(ZQ,n.lens,0,19,n.lencode,0,n.work,G),n.lenbits=G.bits,D){e.msg="invalid code lengths set",n.mode=Je;break}n.have=0,n.mode=d8;case d8:for(;n.have<n.nlen+n.ndist;){for(;b=n.lencode[l&(1<<n.lenbits)-1],y=b>>>24,w=b>>>16&255,A=b&65535,!(y<=u);){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(A<16)l>>>=y,u-=y,n.lens[n.have++]=A;else{if(A===16){for(O=y+2;u<O;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}if(l>>>=y,u-=y,n.have===0){e.msg="invalid bit length repeat",n.mode=Je;break}I=n.lens[n.have-1],d=3+(l&3),l>>>=2,u-=2}else if(A===17){for(O=y+3;u<O;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}l>>>=y,u-=y,I=0,d=3+(l&7),l>>>=3,u-=3}else{for(O=y+7;u<O;){if(s===0)break e;s--,l+=r[a++]<<u,u+=8}l>>>=y,u-=y,I=0,d=11+(l&127),l>>>=7,u-=7}if(n.have+d>n.nlen+n.ndist){e.msg="invalid bit length repeat",n.mode=Je;break}for(;d--;)n.lens[n.have++]=I}}if(n.mode===Je)break;if(n.lens[256]===0){e.msg="invalid code -- missing end-of-block",n.mode=Je;break}if(n.lenbits=9,G={bits:n.lenbits},D=qu(Y5,n.lens,0,n.nlen,n.lencode,0,n.work,G),n.lenbits=G.bits,D){e.msg="invalid literal/lengths set",n.mode=Je;break}if(n.distbits=6,n.distcode=n.distdyn,G={bits:n.distbits},D=qu(Z5,n.lens,n.nlen,n.ndist,n.distcode,0,n.work,G),n.distbits=G.bits,D){e.msg="invalid distances set",n.mode=Je;break}if(n.mode=P0,t===D0)break e;case P0:n.mode=M0;case M0:if(s>=6&&c>=258){e.next_out=o,e.avail_out=c,e.next_in=a,e.avail_in=s,n.hold=l,n.bits=u,VQ(e,h),o=e.next_out,i=e.output,c=e.avail_out,a=e.next_in,r=e.input,s=e.avail_in,l=n.hold,u=n.bits,n.mode===ni&&(n.back=-1);break}for(n.back=0;b=n.lencode[l&(1<<n.lenbits)-1],y=b>>>24,w=b>>>16&255,A=b&65535,!(y<=u);){if(s===0)break 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n=t.readInt32LE(0);if(n===ck||n===c2)return!1;if(n=t.readInt32BE(0),n===ck||n===c2)return!0;throw new Error("not a BigWig/BigBed file")}async _readChromTree(t,n){const r=t.isBigEndian,i=r?"big":"little",a=[],o={};let s=Number(t.unzoomedDataOffset);const c=Number(t.chromTreeOffset);for(;s%4!==0;)s+=1;const l=s-c,{buffer:u}=await this.bbi.read(we.Buffer.alloc(l),0,l,Number(c),n),f=lk(r),{keySize:h}=f.chromTreeParser.parse(u),d=new Fe().endianess(i).string("key",{stripNull:!0,length:h}).uint32("refId").uint32("refSize").saveOffset("offset"),p=new Fe().endianess(i).skip(h).uint64("childOffset").saveOffset("offset"),g=32,b=async y=>{let w=y;if(w>=u.length)throw new Error("reading beyond end of buffer");const A=f.isLeafNode.parse(u.subarray(w)),{isLeafNode:x,cnt:C}=A;if(w+=A.offset,x)for(let _=0;_<C;_+=1){const I=d.parse(u.subarray(w));w+=I.offset;const{key:D,refId:M,refSize:G}=I,O={name:D,id:M,length:G};o[this.renameRefSeqs(D)]=M,a[M]=O}else{const _=[];for(let I=0;I<C;I+=1){const 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k=B,U=xe(),U!==n?(K=OT(),K!==n?(ee=xe(),ee!==n?(oe=LT(),oe!==n?(je=xe(),je!==n?(rt=bp(),rt!==n?(Nn=xe(),Nn!==n?(e.charCodeAt(B)===40?(ga=a,B++):(ga=n,ce===0&&fe(o)),ga!==n?(hi=xe(),hi!==n?(ma=ree(),ma!==n?(di=xe(),di!==n?(e.charCodeAt(B)===41?(ba=s,B++):(ba=n,ce===0&&fe(c)),ba!==n?(pi=xe(),pi!==n?(Zt=k,U=l(K,oe,rt,ma),k=U):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n),k}function OT(){var k;return e.substr(B,6)===u?(k=u,B+=6):(k=n,ce===0&&fe(f)),k===n&&(e.substr(B,6)===h?(k=h,B+=6):(k=n,ce===0&&fe(d)),k===n&&(e.substr(B,5)===p?(k=p,B+=5):(k=n,ce===0&&fe(g)))),k}function LT(){var k,U,K,ee;return k=or(),k===n&&(k=B,U=or(),U!==n?(K=NT(),K!==n?(U=[U,K],k=U):(B=k,k=n)):(B=k,k=n),k===n&&(k=B,U=or(),U!==n?(e.substr(B,4)===b?(K=b,B+=4):(K=n,ce===0&&fe(y)),K!==n?(U=[U,K],k=U):(B=k,k=n)):(B=k,k=n),k===n&&(k=B,U=or(),U!==n?(K=NT(),K!==n?(e.substr(B,4)===b?(ee=b,B+=4):(ee=n,ce===0&&fe(y)),ee!==n?(U=[U,K,ee],k=U):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)))),k}function NT(){var k;return e.substr(B,7)===w?(k=w,B+=7):(k=n,ce===0&&fe(A)),k===n&&(e.substr(B,5)===x?(k=x,B+=5):(k=n,ce===0&&fe(C)),k===n&&(e.substr(B,6)===_?(k=_,B+=6):(k=n,ce===0&&fe(I)))),k}function bp(){var k;return k=zT(),k===n&&(k=xe()),k}function ree(){var k,U,K,ee,oe,je,rt;if(k=B,U=q2(),U!==n)if(K=xe(),K!==n){for(ee=[],oe=B,je=xe(),je!==n?(rt=q2(),rt!==n?(Zt=oe,je=D(U,rt),oe=je):(B=oe,oe=n)):(B=oe,oe=n);oe!==n;)ee.push(oe),oe=B,je=xe(),je!==n?(rt=q2(),rt!==n?(Zt=oe,je=D(U,rt),oe=je):(B=oe,oe=n)):(B=oe,oe=n);ee!==n?(oe=xe(),oe!==n?(Zt=k,U=M(U,ee),k=U):(B=k,k=n)):(B=k,k=n)}else B=k,k=n;else B=k,k=n;return k}function iee(){var k;return e.charCodeAt(B)===35?(k=G,B++):(k=n,ce===0&&fe(O)),k}function aee(){var k,U,K,ee,oe;return k=B,U=xe(),U!==n?(K=iee(),K!==n?(ee=zT(),ee!==n?(oe=xe(),oe!==n?(U=[U,K,ee,oe],k=U):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n),k}function q2(){var k,U,K,ee,oe,je,rt,Nn,ga,hi,ma,di,ba,pi;return k=B,U=W2(),U!==n?(K=xe(),K!==n?(ee=or(),ee!==n?(oe=xe(),oe!==n?(e.charCodeAt(B)===59?(je=ae,B++):(je=n,ce===0&&fe(se)),je!==n?(rt=xe(),rt!==n?(Nn=bp(),Nn!==n?(Zt=k,U=ve(U,ee,Nn),k=U):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n),k===n&&(k=B,U=W2(),U!==n?(K=xe(),K!==n?(e.charCodeAt(B)===91?(ee=Pe,B++):(ee=n,ce===0&&fe(st)),ee!==n?(oe=xe(),oe!==n?(je=see(),je!==n?(rt=xe(),rt!==n?(e.charCodeAt(B)===93?(Nn=Ne,B++):(Nn=n,ce===0&&fe(lt)),Nn!==n?(ga=xe(),ga!==n?(hi=or(),hi!==n?(ma=xe(),ma!==n?(e.charCodeAt(B)===59?(di=ae,B++):(di=n,ce===0&&fe(se)),di!==n?(ba=xe(),ba!==n?(pi=bp(),pi!==n?(Zt=k,U=tt(U,je,hi,pi),k=U):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n),k===n&&(k=B,U=W2(),U!==n?(K=xe(),K!==n?(e.charCodeAt(B)===40?(ee=a,B++):(ee=n,ce===0&&fe(o)),ee!==n?(oe=xe(),oe!==n?(je=oee(),je!==n?(rt=xe(),rt!==n?(e.charCodeAt(B)===41?(Nn=s,B++):(Nn=n,ce===0&&fe(c)),Nn!==n?(ga=xe(),ga!==n?(hi=or(),hi!==n?(ma=xe(),ma!==n?(e.charCodeAt(B)===59?(di=ae,B++):(di=n,ce===0&&fe(se)),di!==n?(ba=xe(),ba!==n?(pi=bp(),pi!==n?(Zt=k,U=ut(U,je,hi,pi),k=U):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n)):(B=k,k=n),k===n&&(k=aee()))),k}function oee(){var k,U,K,ee,oe,je,rt;if(k=B,U=or(),U!==n){for(K=[],ee=B,e.charCodeAt(B)===44?(oe=Te,B++):(oe=n,ce===0&&fe(Ie)),oe!==n?(je=xe(),je!==n?(rt=or(),rt!==n?(Zt=ee,oe=D(U,rt),ee=oe):(B=ee,ee=n)):(B=ee,ee=n)):(B=ee,ee=n);ee!==n;)K.push(ee),ee=B,e.charCodeAt(B)===44?(oe=Te,B++):(oe=n,ce===0&&fe(Ie)),oe!==n?(je=xe(),je!==n?(rt=or(),rt!==n?(Zt=ee,oe=D(U,rt),ee=oe):(B=ee,ee=n)):(B=ee,ee=n)):(B=ee,ee=n);K!==n?(Zt=k,U=Rt(U,K),k=U):(B=k,k=n)}else B=k,k=n;return k}function W2(){var k,U,K,ee;return e.substr(B,3)===ln?(k=ln,B+=3):(k=n,ce===0&&fe(Ve)),k===n&&(e.substr(B,4)===N?(k=N,B+=4):(k=n,ce===0&&fe(L)),k===n&&(e.substr(B,5)===W?(k=W,B+=5):(k=n,ce===0&&fe(j)),k===n&&(e.substr(B,6)===Q?(k=Q,B+=6):(k=n,ce===0&&fe(T)),k===n&&(e.substr(B,4)===S?(k=S,B+=4):(k=n,ce===0&&fe(V)),k===n&&(e.substr(B,5)===Y?(k=Y,B+=5):(k=n,ce===0&&fe(de)),k===n&&(e.substr(B,5)===ie?(k=ie,B+=5):(k=n,ce===0&&fe(pe)),k===n&&(e.substr(B,4)===un?(k=un,B+=4):(k=n,ce===0&&fe(fa)),k===n&&(e.substr(B,6)===ha?(k=ha,B+=6):(k=n,ce===0&&fe(da)),k===n&&(e.substr(B,7)===Gt?(k=Gt,B+=7):(k=n,ce===0&&fe(fi)),k===n&&(e.substr(B,4)===pa?(k=pa,B+=4):(k=n,ce===0&&fe(fn)),k===n&&(e.substr(B,6)===Br?(k=Br,B+=6):(k=n,ce===0&&fe(E)),k===n&&(e.substr(B,6)===m?(k=m,B+=6):(k=n,ce===0&&fe(v)),k===n&&(e.substr(B,3)===R?(k=R,B+=3):(k=n,ce===0&&fe(P)),k===n&&(k=B,U=OT(),U!==n?(K=xe(),K!==n?(ee=LT(),ee!==n?(Zt=k,U=z(U,ee),k=U):(B=k,k=n)):(B=k,k=n)):(B=k,k=n))))))))))))))),k}function see(){var k;return k=cee(),k===n&&(k=or()),k}function or(){var k,U,K,ee,oe;if(k=B,U=B,q.test(e.charAt(B))?(K=e.charAt(B),B++):(K=n,ce===0&&fe(ge)),K!==n){for(ee=[],Ze.test(e.charAt(B))?(oe=e.charAt(B),B++):(oe=n,ce===0&&fe($e));oe!==n;)ee.push(oe),Ze.test(e.charAt(B))?(oe=e.charAt(B),B++):(oe=n,ce===0&&fe($e));ee!==n?(K=[K,ee],U=K):(B=U,U=n)}else B=U,U=n;return U!==n&&(Zt=k,U=nt()),k=U,k}function zT(){var k,U,K;for(k=B,U=[],Re.test(e.charAt(B))?(K=e.charAt(B),B++):(K=n,ce===0&&fe(CT));K!==n;)U.push(K),Re.test(e.charAt(B))?(K=e.charAt(B),B++):(K=n,ce===0&&fe(CT));return U!==n&&(Zt=k,U=XJ(U)),k=U,k}function cee(){var k,U,K,ee;if(ce++,k=B,U=xe(),U!==n){if(K=[],kT.test(e.charAt(B))?(ee=e.charAt(B),B++):(ee=n,ce===0&&fe(TT)),ee!==n)for(;ee!==n;)K.push(ee),kT.test(e.charAt(B))?(ee=e.charAt(B),B++):(ee=n,ce===0&&fe(TT));else K=n;K!==n?(Zt=k,U=JJ(),k=U):(B=k,k=n)}else B=k,k=n;return ce--,k===n&&(U=n,ce===0&&fe(KJ)),k}function xe(){var k,U;for(ce++,k=[],IT.test(e.charAt(B))?(U=e.charAt(B),B++):(U=n,ce===0&&fe(RT));U!==n;)k.push(U),IT.test(e.charAt(B))?(U=e.charAt(B),B++):(U=n,ce===0&&fe(RT));return ce--,k===n&&(U=n,ce===0&&fe(eee)),k}if(mp=i(),mp!==n&&B===e.length)return mp;throw mp!==n&&B<e.length&&fe(tee()),nee(j2,Fr<e.length?e.charAt(Fr):null,Fr<e.length?PT(Fr,Fr+1):PT(Fr,Fr))}var hk={SyntaxError:ec,parse:DK};const BK=uu(hk),l2=Object.fromEntries(Object.entries(Object.freeze(Object.defineProperty({__proto__:null,bigChain:`table bigChain
|
|
3278
3281
|
"bigChain pairwise alignment"
|
|
3279
3282
|
(
|
|
3280
3283
|
string chrom; "Reference sequence chromosome or scaffold"
|
|
@@ -3433,17 +3436,17 @@ ${n}</textarea
|
|
|
3433
3436
|
float score; "Floating point score."
|
|
3434
3437
|
char[1] leftStatus; "Gap/break annotation for preceding block"
|
|
3435
3438
|
char[1] rightStatus; "Gap/break annotation for following block"
|
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3436
|
-
)`},Symbol.toStringTag,{value:"Module"}))).map(([e,t])=>[e,hk.parse(t.trim())]));function u2(e){const t=["uint","int","float","long"];return{...e,fields:e.fields.map(n=>({...n,isArray:n.size&&n.type!=="char",arrayIsNumeric:n.size&&t.includes(n.type),isNumeric:!n.size&&t.includes(n.type)}))}}const BK={".":0,"-":-1,"+":1};function FK(e){var t;return e.length>=12&&!Number.isNaN(parseInt(e[9],10))&&((t=e[10])===null||t===void 0?void 0:t.split(",").filter(n=>!!n).length)===parseInt(e[9],10)}class PK{constructor(t={}){if(t.autoSql)this.autoSql=u2(DK.parse(t.autoSql));else if(t.type){if(!l2[t.type])throw new Error("Type not found");this.autoSql=u2(l2[t.type])}else this.autoSql=u2(l2.defaultBedSchema),this.attemptDefaultBed=!0}parseLine(t,n={}){const{autoSql:r}=this,{uniqueId:i}=n,a=Array.isArray(t)?t:t.split(" ");let o={};if(!this.attemptDefaultBed||this.attemptDefaultBed&&FK(a))for(let s=0;s<r.fields.length;s++){const c=r.fields[s];let l=a[s];const{isNumeric:u,isArray:f,arrayIsNumeric:h,name:d}=c;if(l==null)break;if(l!=="."){if(u){const p=Number(l);l=Number.isNaN(p)?l:p}else f&&(l=l.split(","),l[l.length-1]===""&&l.pop(),h&&(l=l.map(p=>Number(p))));o[d]=l}}else{const s=["chrom","chromStart","chromEnd","name"];o=Object.fromEntries(a.map((c,l)=>[s[l]||"field"+l,c])),o.chromStart=+o.chromStart,o.chromEnd=+o.chromEnd,Number.isNaN(Number.parseFloat(o.field4))||(o.score=+o.field4,delete o.field4),(o.field5==="+"||o.field5==="-")&&(o.strand=o.field5,delete o.field5)}return i&&(o.uniqueId=i),o.strand=BK[o.strand]||0,o.chrom=decodeURIComponent(o.chrom),o}}const MK=Object.freeze(Object.defineProperty({__proto__:null,default:PK},Symbol.toStringTag,{value:"Module"}));let dk=class{constructor(t,n){this.blockPosition=t,this.dataPosition=n}toString(){return`${this.blockPosition}:${this.dataPosition}`}compareTo(t){return this.blockPosition-t.blockPosition||this.dataPosition-t.dataPosition}static min(...t){let n,r=0;for(;!n;r+=1)n=t[r];for(;r<t.length;r+=1)n.compareTo(t[r])>0&&(n=t[r]);return n}};function tc(e,t=0,n=!1){if(n)throw new Error("big-endian virtual file offsets not implemented");return new dk(e[t+7]*1099511627776+e[t+6]*4294967296+e[t+5]*16777216+e[t+4]*65536+e[t+3]*256+e[t+2],e[t+1]<<8|e[t])}let pk=class{constructor(t,n,r,i){this.minv=t,this.maxv=n,this.bin=r,this._fetchedSize=i}toUniqueString(){return`${this.minv}..${this.maxv} (bin ${this.bin}, fetchedSize ${this.fetchedSize()})`}toString(){return this.toUniqueString()}compareTo(t){return this.minv.compareTo(t.minv)||this.maxv.compareTo(t.maxv)||this.bin-t.bin}fetchedSize(){return this._fetchedSize!==void 0?this._fetchedSize:this.maxv.blockPosition+65536-this.minv.blockPosition}};function OK(e){return new Promise(t=>setTimeout(t,e))}function LK(e){if(e.greaterThan(Number.MAX_SAFE_INTEGER)||e.lessThan(Number.MIN_SAFE_INTEGER))throw new Error("integer overflow");return e.toNumber()}function NK(e){if(e&&e.aborted)if(typeof DOMException>"u"){const t=new Error("aborted");throw t.code="ERR_ABORTED",t}else throw new DOMException("aborted","AbortError")}function zK(e,t){return t.minv.blockPosition-e.maxv.blockPosition<65e3&&t.maxv.blockPosition-e.minv.blockPosition<5e6}function UK(e={}){return"aborted"in e?{signal:e}:e}function gk(e,t){const n=[];let r;if(e.length===0)return e;e.sort((i,a)=>{const o=i.minv.blockPosition-a.minv.blockPosition;return o===0?i.minv.dataPosition-a.minv.dataPosition:o});for(const i of e)(!t||i.maxv.compareTo(t)>0)&&(r===void 0?(n.push(i),r=i):zK(r,i)?i.maxv.compareTo(r.maxv)>0&&(r.maxv=i.maxv):(n.push(i),r=i));return n}function mk(e,t){return{lineCount:LK(p0.fromBytesLE(Array.prototype.slice.call(e,t,t+8),!0))}}function z0(e,t){return e?e.compareTo(t)>0?t:e:t}function $K(e,t=n=>n){let n=0,r=0;const i=[],a={};for(let o=0;o<e.length;o+=1)if(!e[o]){if(r<o){let s=e.toString("utf8",r,o);s=t(s),i[n]=s,a[s]=n}r=o+1,n+=1}return{refNameToId:a,refIdToName:i}}let bk=class{constructor({filehandle:t,renameRefSeq:n=r=>r}){this.filehandle=t,this.renameRefSeq=n}};const HK=21578050;function GK(e,t){return e-e%t}function VK(e,t){return e-e%t+t}function jK(e,t){return t-=1,[[0,0],[1+(e>>26),1+(t>>26)],[9+(e>>23),9+(t>>23)],[73+(e>>20),73+(t>>20)],[585+(e>>17),585+(t>>17)],[4681+(e>>14),4681+(t>>14)]]}class nc extends bk{async lineCount(t,n){var r,i;return((i=(r=(await this.parse(n)).indices[t])===null||r===void 0?void 0:r.stats)===null||i===void 0?void 0:i.lineCount)||0}async _parse(t){const n=await this.filehandle.readFile(t);if(n.readUInt32LE(0)!==HK)throw new Error("Not a BAI file");const r=n.readInt32LE(4),a=((1<<(5+1)*3)-1)/7;let o=8,s;const c=new Array(r);for(let l=0;l<r;l++){const u=n.readInt32LE(o);let f;o+=4;const h={};for(let g=0;g<u;g+=1){const b=n.readUInt32LE(o);if(o+=4,b===a+1)o+=4,f=mk(n,o+16),o+=32;else{if(b>a+1)throw new Error("bai index contains too many bins, please use CSI");{const y=n.readInt32LE(o);o+=4;const w=new Array(y);for(let A=0;A<y;A++){const x=tc(n,o);o+=8;const C=tc(n,o);o+=8,s=z0(s,x),w[A]=new pk(x,C,b)}h[b]=w}}}const d=n.readInt32LE(o);o+=4;const p=new Array(d);for(let g=0;g<d;g++){const b=tc(n,o);o+=8,s=z0(s,b),p[g]=b}c[l]={binIndex:h,linearIndex:p,stats:f}}return{bai:!0,firstDataLine:s,maxBlockSize:65536,indices:c,refCount:r}}async indexCov(t,n,r,i={}){const o=n!==void 0,c=(await this.parse(i)).indices[t];if(!c)return[];const{linearIndex:l=[],stats:u}=c;if(l.length===0)return[];const f=r===void 0?(l.length-1)*16384:VK(r,16384),h=n===void 0?0:GK(n,16384),d=o?new Array((f-h)/16384):new Array(l.length-1),p=l[l.length-1].blockPosition;if(f>(l.length-1)*16384)throw new Error("query outside of range of linear index");let g=l[h/16384].blockPosition;for(let b=h/16384,y=0;b<f/16384;b++,y++)d[y]={score:l[b+1].blockPosition-g,start:b*16384,end:b*16384+16384},g=l[b+1].blockPosition;return d.map(b=>({...b,score:b.score*((u==null?void 0:u.lineCount)||0)/p}))}async blocksForRange(t,n,r,i={}){n<0&&(n=0);const a=await this.parse(i);if(!a)return[];const o=a.indices[t];if(!o)return[];const s=jK(n,r),c=[];for(const[d,p]of s)for(let g=d;g<=p;g++)if(o.binIndex[g]){const b=o.binIndex[g];for(const y of b)c.push(y)}const l=o.linearIndex.length;let u;const f=Math.min(n>>14,l-1),h=Math.min(r>>14,l-1);for(let d=f;d<=h;++d){const p=o.linearIndex[d];p&&(!u||p.compareTo(u)<0)&&(u=p)}return gk(c,u)}async parse(t={}){return this.setupP||(this.setupP=this._parse(t).catch(n=>{throw this.setupP=void 0,n})),this.setupP}async hasRefSeq(t,n={}){var r;return!!(!((r=(await this.parse(n)).indices[t])===null||r===void 0)&&r.binIndex)}}var ca=we.Buffer,f2=[0,1996959894,3993919788,2567524794,124634137,1886057615,3915621685,2657392035,249268274,2044508324,3772115230,2547177864,162941995,2125561021,3887607047,2428444049,498536548,1789927666,4089016648,2227061214,450548861,1843258603,4107580753,2211677639,325883990,1684777152,4251122042,2321926636,335633487,1661365465,4195302755,2366115317,997073096,1281953886,3579855332,2724688242,1006888145,1258607687,3524101629,2768942443,901097722,1119000684,3686517206,2898065728,853044451,1172266101,3705015759,2882616665,651767980,1373503546,3369554304,3218104598,565507253,1454621731,3485111705,3099436303,671266974,1594198024,3322730930,2970347812,795835527,1483230225,3244367275,3060149565,1994146192,31158534,2563907772,4023717930,1907459465,112637215,2680153253,3904427059,2013776290,251722036,2517215374,3775830040,2137656763,141376813,2439277719,3865271297,1802195444,476864866,2238001368,4066508878,1812370925,453092731,2181625025,4111451223,1706088902,314042704,2344532202,4240017532,1658658271,366619977,2362670323,4224994405,1303535960,984961486,2747007092,3569037538,1256170817,1037604311,2765210733,3554079995,1131014506,879679996,2909243462,3663771856,1141124467,855842277,2852801631,3708648649,1342533948,654459306,3188396048,3373015174,1466479909,544179635,3110523913,3462522015,1591671054,702138776,2966460450,3352799412,1504918807,783551873,3082640443,3233442989,3988292384,2596254646,62317068,1957810842,3939845945,2647816111,81470997,1943803523,3814918930,2489596804,225274430,2053790376,3826175755,2466906013,167816743,2097651377,4027552580,2265490386,503444072,1762050814,4150417245,2154129355,426522225,1852507879,4275313526,2312317920,282753626,1742555852,4189708143,2394877945,397917763,1622183637,3604390888,2714866558,953729732,1340076626,3518719985,2797360999,1068828381,1219638859,3624741850,2936675148,906185462,1090812512,3747672003,2825379669,829329135,1181335161,3412177804,3160834842,628085408,1382605366,3423369109,3138078467,570562233,1426400815,3317316542,2998733608,733239954,1555261956,3268935591,3050360625,752459403,1541320221,2607071920,3965973030,1969922972,40735498,2617837225,3943577151,1913087877,83908371,2512341634,3803740692,2075208622,213261112,2463272603,3855990285,2094854071,198958881,2262029012,4057260610,1759359992,534414190,2176718541,4139329115,1873836001,414664567,2282248934,4279200368,1711684554,285281116,2405801727,4167216745,1634467795,376229701,2685067896,3608007406,1308918612,956543938,2808555105,3495958263,1231636301,1047427035,2932959818,3654703836,1088359270,936918e3,2847714899,3736837829,1202900863,817233897,3183342108,3401237130,1404277552,615818150,3134207493,3453421203,1423857449,601450431,3009837614,3294710456,1567103746,711928724,3020668471,3272380065,1510334235,755167117];typeof Int32Array<"u"&&(f2=new Int32Array(f2));function yk(e){if(ca.isBuffer(e))return e;var t=typeof ca.alloc=="function"&&typeof ca.from=="function";if(typeof e=="number")return t?ca.alloc(e):new ca(e);if(typeof e=="string")return t?ca.from(e):new ca(e);throw new Error("input must be buffer, number, or string, received "+typeof e)}function qK(e){var t=yk(4);return t.writeInt32BE(e,0),t}function h2(e,t){e=yk(e),ca.isBuffer(t)&&(t=t.readUInt32BE(0));for(var n=~~t^-1,r=0;r<e.length;r++)n=f2[(n^e[r])&255]^n>>>8;return n^-1}function d2(){return qK(h2.apply(null,arguments))}d2.signed=function(){return h2.apply(null,arguments)},d2.unsigned=function(){return h2.apply(null,arguments)>>>0};var WK=d2;const YK=uu(WK),ZK=21582659,QK=38359875;function XK(e,t){return e*2**t}function vk(e,t){return Math.floor(e/2**t)}let U0=class extends bk{constructor(){super(...arguments),this.maxBinNumber=0,this.depth=0,this.minShift=0}async lineCount(t,n){var r,i;return((i=(r=(await this.parse(n)).indices[t])===null||r===void 0?void 0:r.stats)===null||i===void 0?void 0:i.lineCount)||0}async indexCov(){return[]}parseAuxData(t,n){const r=t.readInt32LE(n),i=r&65536?"zero-based-half-open":"1-based-closed",a={0:"generic",1:"SAM",2:"VCF"}[r&15];if(!a)throw new Error(`invalid Tabix preset format flags ${r}`);const o={ref:t.readInt32LE(n+4),start:t.readInt32LE(n+8),end:t.readInt32LE(n+12)},s=t.readInt32LE(n+16),c=s?String.fromCharCode(s):"",l=t.readInt32LE(n+20),u=t.readInt32LE(n+24);return{columnNumbers:o,coordinateType:i,metaValue:s,metaChar:c,skipLines:l,format:a,formatFlags:r,...$K(t.subarray(n+28,n+28+u),this.renameRefSeq)}}async _parse(t){const n=await this.filehandle.readFile(t),r=await ea(n);let i;if(r.readUInt32LE(0)===ZK)i=1;else if(r.readUInt32LE(0)===QK)i=2;else throw new Error("Not a CSI file");this.minShift=r.readInt32LE(4),this.depth=r.readInt32LE(8),this.maxBinNumber=((1<<(this.depth+1)*3)-1)/7;const a=r.readInt32LE(12),o=a>=30?this.parseAuxData(r,16):void 0,s=r.readInt32LE(16+a);let c=16+a+4,l;const u=new Array(s);for(let f=0;f<s;f++){const h=r.readInt32LE(c);c+=4;const d={};let p;for(let g=0;g<h;g++){const b=r.readUInt32LE(c);if(c+=4,b>this.maxBinNumber)p=mk(r,c+28),c+=28+16;else{l=z0(l,tc(r,c)),c+=8;const y=r.readInt32LE(c);c+=4;const w=new Array(y);for(let A=0;A<y;A+=1){const x=tc(r,c);c+=8;const C=tc(r,c);c+=8,l=z0(l,x),w[A]=new pk(x,C,b)}d[b]=w}}u[f]={binIndex:d,stats:p}}return{csiVersion:i,firstDataLine:l,indices:u,refCount:s,csi:!0,maxBlockSize:65536,...o}}async blocksForRange(t,n,r,i={}){n<0&&(n=0);const a=await this.parse(i),o=a==null?void 0:a.indices[t];if(!o)return[];const s=this.reg2bins(n,r);if(s.length===0)return[];const c=[];for(const[l,u]of s)for(let f=l;f<=u;f++)if(o.binIndex[f]){const h=o.binIndex[f];for(const d of h)c.push(d)}return gk(c,new dk(0,0))}reg2bins(t,n){t-=1,t<1&&(t=1),n>2**50&&(n=2**34),n-=1;let r=0,i=0,a=this.minShift+this.depth*3;const o=[];for(;r<=this.depth;a-=3,i+=XK(1,r*3),r+=1){const s=i+vk(t,a),c=i+vk(n,a);if(c-s+o.length>this.maxBinNumber)throw new Error(`query ${t}-${n} is too large for current binning scheme (shift ${this.minShift}, depth ${this.depth}), try a smaller query or a coarser index binning scheme`);o.push([s,c])}return o}async parse(t={}){return this.setupP||(this.setupP=this._parse(t).catch(n=>{throw this.setupP=void 0,n})),this.setupP}async hasRefSeq(t,n={}){var r;return!!(!((r=(await this.parse(n)).indices[t])===null||r===void 0)&&r.binIndex)}};const Mn={BAM_FPAIRED:1,BAM_FPROPER_PAIR:2,BAM_FUNMAP:4,BAM_FMUNMAP:8,BAM_FREVERSE:16,BAM_FMREVERSE:32,BAM_FREAD1:64,BAM_FREAD2:128,BAM_FSECONDARY:256,BAM_FQCFAIL:512,BAM_FDUP:1024,BAM_FSUPPLEMENTARY:2048},wk="=ACMGRSVTWYHKDBN".split(""),Xu="MIDNSHP=X???????".split("");class xk{constructor(t){this.data={},this._tagList=[],this._allTagsParsed=!1;const{bytes:n,fileOffset:r}=t,{byteArray:i,start:a}=n;this.data={},this.bytes=n,this._id=r,this._refID=i.readInt32LE(a+4),this.data.start=i.readInt32LE(a+8),this.flags=(i.readInt32LE(a+16)&4294901760)>>16}get(t){return this[t]?this.data[t]?this.data[t]:(this.data[t]=this[t](),this.data[t]):this._get(t.toLowerCase())}end(){return this.get("start")+this.get("length_on_ref")}seq_id(){return this._refID}_get(t){return t in this.data?this.data[t]:(this.data[t]=this._parseTag(t),this.data[t])}_tags(){this._parseAllTags();let t=["seq"];this.isSegmentUnmapped()||t.push("start","end","strand","score","qual","MQ","CIGAR","length_on_ref","template_length"),this.isPaired()&&t.push("next_segment_position","pair_orientation"),t=t.concat(this._tagList||[]);for(const r of Object.keys(this.data))r[0]!=="_"&&r!=="next_seq_id"&&t.push(r);const n={};return t.filter(r=>{if(r in this.data&&this.data[r]===void 0||r==="CG"||r==="cg")return!1;const i=r.toLowerCase(),a=n[i];return n[i]=!0,!a})}parent(){}children(){return this.get("subfeatures")}id(){return this._id}mq(){const t=(this.get("_bin_mq_nl")&65280)>>8;return t===255?void 0:t}score(){return this.get("mq")}qual(){var t;return(t=this.qualRaw())===null||t===void 0?void 0:t.join(" ")}qualRaw(){if(this.isSegmentUnmapped())return;const{start:t,byteArray:n}=this.bytes,r=t+36+this.get("_l_read_name")+this.get("_n_cigar_op")*4+this.get("_seq_bytes"),i=this.get("seq_length");return n.subarray(r,r+i)}strand(){return this.isReverseComplemented()?-1:1}multi_segment_next_segment_strand(){if(!this.isMateUnmapped())return this.isMateReverseComplemented()?-1:1}name(){return this.get("_read_name")}_read_name(){const t=this.get("_l_read_name"),{byteArray:n,start:r}=this.bytes;return n.toString("ascii",r+36,r+36+t-1)}_parseTag(t){if(this._allTagsParsed)return;const{byteArray:n,start:r}=this.bytes;let i=this._tagOffset||r+36+this.get("_l_read_name")+this.get("_n_cigar_op")*4+this.get("_seq_bytes")+this.get("seq_length");const a=this.bytes.end;let o;for(;i<a&&o!==t;){const s=String.fromCharCode(n[i],n[i+1]);o=s.toLowerCase();const c=String.fromCharCode(n[i+2]);i+=3;let l;switch(c){case"A":{l=String.fromCharCode(n[i]),i+=1;break}case"i":{l=n.readInt32LE(i),i+=4;break}case"I":{l=n.readUInt32LE(i),i+=4;break}case"c":{l=n.readInt8(i),i+=1;break}case"C":{l=n.readUInt8(i),i+=1;break}case"s":{l=n.readInt16LE(i),i+=2;break}case"S":{l=n.readUInt16LE(i),i+=2;break}case"f":{l=n.readFloatLE(i),i+=4;break}case"Z":case"H":{for(l="";i<=a;){const u=n[i++];if(u===0)break;l+=String.fromCharCode(u)}break}case"B":{l="";const u=n[i++],f=String.fromCharCode(u),h=n.readInt32LE(i);if(i+=4,f==="i")if(s==="CG")for(let d=0;d<h;d++){const p=n.readInt32LE(i),g=p>>4,b=Xu[p&15];l+=g+b,i+=4}else for(let d=0;d<h;d++)l+=n.readInt32LE(i),d+1<h&&(l+=","),i+=4;if(f==="I")if(s==="CG")for(let d=0;d<h;d++){const p=n.readUInt32LE(i),g=p>>4,b=Xu[p&15];l+=g+b,i+=4}else for(let d=0;d<h;d++)l+=n.readUInt32LE(i),d+1<h&&(l+=","),i+=4;if(f==="s")for(let d=0;d<h;d++)l+=n.readInt16LE(i),d+1<h&&(l+=","),i+=2;if(f==="S")for(let d=0;d<h;d++)l+=n.readUInt16LE(i),d+1<h&&(l+=","),i+=2;if(f==="c")for(let d=0;d<h;d++)l+=n.readInt8(i),d+1<h&&(l+=","),i+=1;if(f==="C")for(let d=0;d<h;d++)l+=n.readUInt8(i),d+1<h&&(l+=","),i+=1;if(f==="f")for(let d=0;d<h;d++)l+=n.readFloatLE(i),d+1<h&&(l+=","),i+=4;break}default:console.warn(`Unknown BAM tag type '${c}', tags may be incomplete`),l=void 0,i=a}if(this._tagOffset=i,this._tagList.push(s),o===t)return l;this.data[o]=l}this._allTagsParsed=!0}_parseAllTags(){this._parseTag("")}_parseCigar(t){return t.match(/\d+\D/g).map(n=>[n.match(/\D/)[0].toUpperCase(),Number.parseInt(n,10)])}isPaired(){return!!(this.flags&Mn.BAM_FPAIRED)}isProperlyPaired(){return!!(this.flags&Mn.BAM_FPROPER_PAIR)}isSegmentUnmapped(){return!!(this.flags&Mn.BAM_FUNMAP)}isMateUnmapped(){return!!(this.flags&Mn.BAM_FMUNMAP)}isReverseComplemented(){return!!(this.flags&Mn.BAM_FREVERSE)}isMateReverseComplemented(){return!!(this.flags&Mn.BAM_FMREVERSE)}isRead1(){return!!(this.flags&Mn.BAM_FREAD1)}isRead2(){return!!(this.flags&Mn.BAM_FREAD2)}isSecondary(){return!!(this.flags&Mn.BAM_FSECONDARY)}isFailedQc(){return!!(this.flags&Mn.BAM_FQCFAIL)}isDuplicate(){return!!(this.flags&Mn.BAM_FDUP)}isSupplementary(){return!!(this.flags&Mn.BAM_FSUPPLEMENTARY)}cigar(){if(this.isSegmentUnmapped())return;const{byteArray:t,start:n}=this.bytes,r=this.get("_n_cigar_op");let i=n+36+this.get("_l_read_name");const a=this.get("seq_length");let o="",s=0,c=t.readInt32LE(i),l=c>>4,u=Xu[c&15];if(u==="S"&&l===a)return i+=4,c=t.readInt32LE(i),l=c>>4,u=Xu[c&15],u!=="N"&&console.warn("CG tag with no N tag"),this.data.length_on_ref=l,this.get("CG");for(let f=0;f<r;++f)c=t.readInt32LE(i),l=c>>4,u=Xu[c&15],o+=l+u,u!=="H"&&u!=="S"&&u!=="I"&&(s+=l),i+=4;return this.data.length_on_ref=s,o}_flags(){}length_on_ref(){return this.data.length_on_ref?this.data.length_on_ref:(this.get("cigar"),this.data.length_on_ref)}_n_cigar_op(){return this.get("_flag_nc")&65535}_l_read_name(){return this.get("_bin_mq_nl")&255}_seq_bytes(){return this.get("seq_length")+1>>1}getReadBases(){return this.seq()}seq(){const{byteArray:t,start:n}=this.bytes,r=n+36+this.get("_l_read_name")+this.get("_n_cigar_op")*4,i=this.get("_seq_bytes"),a=this.get("seq_length");let o="",s=0;for(let c=0;c<i;++c){const l=t[r+c];o+=wk[(l&240)>>4],s++,s<a&&(o+=wk[l&15],s++)}return o}getPairOrientation(){if(!this.isSegmentUnmapped()&&!this.isMateUnmapped()&&this._refID===this._next_refid()){const t=this.isReverseComplemented()?"R":"F",n=this.isMateReverseComplemented()?"R":"F";let r=" ",i=" ";this.isRead1()?(r="1",i="2"):this.isRead2()&&(r="2",i="1");const a=[];return this.template_length()>0?(a[0]=t,a[1]=r,a[2]=n,a[3]=i):(a[2]=t,a[3]=r,a[0]=n,a[1]=i),a.join("")}return""}_bin_mq_nl(){return this.bytes.byteArray.readInt32LE(this.bytes.start+12)}_flag_nc(){return this.bytes.byteArray.readInt32LE(this.bytes.start+16)}seq_length(){return this.bytes.byteArray.readInt32LE(this.bytes.start+20)}_next_refid(){return this.bytes.byteArray.readInt32LE(this.bytes.start+24)}_next_pos(){return this.bytes.byteArray.readInt32LE(this.bytes.start+28)}template_length(){return this.bytes.byteArray.readInt32LE(this.bytes.start+32)}toJSON(){const t={};for(const n of Object.keys(this))n.charAt(0)==="_"||n==="bytes"||(t[n]=this[n]);return t}}function Ak(e){const t=e.split(/\r?\n/),n=[];for(const r of t){const[i,...a]=r.split(/\t/);i&&n.push({tag:i.slice(1),data:a.map(o=>{const[s,c]=o.split(":",2);return{tag:s,value:c}})})}return n}const Ek=21840194,Sk=65536;async function KK(e){let t=[];for await(const n of e)t=t.concat(n);return t}class JK{read(){throw new Error("never called")}stat(){throw new Error("never called")}readFile(){throw new Error("never called")}close(){throw new Error("never called")}}class _k{constructor({bamFilehandle:t,bamPath:n,bamUrl:r,baiPath:i,baiFilehandle:a,baiUrl:o,csiPath:s,csiFilehandle:c,csiUrl:l,htsget:u,yieldThreadTime:f=100,renameRefSeqs:h=d=>d}){if(this.htsget=!1,this.featureCache=new A0({cache:new E0({maxSize:50}),fill:async(d,p)=>{const{chunk:g,opts:b}=d,{data:y,cpositions:w,dpositions:A}=await this._readChunk({chunk:g,opts:{...b,signal:p}});return this.readBamFeatures(y,w,A,g)}}),this.renameRefSeq=h,t)this.bam=t;else if(n)this.bam=new kt(n);else if(r)this.bam=new po(r);else if(u)this.htsget=!0,this.bam=new JK;else throw new Error("unable to initialize bam");if(c)this.index=new U0({filehandle:c});else if(s)this.index=new U0({filehandle:new kt(s)});else if(l)this.index=new U0({filehandle:new po(l)});else if(a)this.index=new nc({filehandle:a});else if(i)this.index=new nc({filehandle:new kt(i)});else if(o)this.index=new nc({filehandle:new po(o)});else if(n)this.index=new nc({filehandle:new kt(`${n}.bai`)});else if(r)this.index=new nc({filehandle:new po(`${r}.bai`)});else if(u)this.htsget=!0;else throw new Error("unable to infer index format");this.yieldThreadTime=f}async getHeaderPre(t){const n=UK(t);if(!this.index)return;const r=await this.index.parse(n),i=r.firstDataLine?r.firstDataLine.blockPosition+65535:void 0;let a;if(i){const u=i+Sk,f=await this.bam.read(we.Buffer.alloc(u),0,u,0,n);if(!f.bytesRead)throw new Error("Error reading header");a=f.buffer.subarray(0,Math.min(f.bytesRead,i))}else a=await this.bam.readFile(n);const o=await ea(a);if(o.readInt32LE(0)!==Ek)throw new Error("Not a BAM file");const s=o.readInt32LE(4);this.header=o.toString("utf8",8,8+s);const{chrToIndex:c,indexToChr:l}=await this._readRefSeqs(s+8,65535,n);return this.chrToIndex=c,this.indexToChr=l,Ak(this.header)}getHeader(t){return this.headerP||(this.headerP=this.getHeaderPre(t).catch(n=>{throw this.headerP=void 0,n})),this.headerP}async getHeaderText(t={}){return await this.getHeader(t),this.header}async _readRefSeqs(t,n,r){if(t>n)return this._readRefSeqs(t,n*2,r);const i=n+Sk,{bytesRead:a,buffer:o}=await this.bam.read(we.Buffer.alloc(i),0,n,0,r);if(!a)throw new Error("Error reading refseqs from header");const s=await ea(o.subarray(0,Math.min(a,n))),c=s.readInt32LE(t);let l=t+4;const u={},f=[];for(let h=0;h<c;h+=1){const d=s.readInt32LE(l),p=this.renameRefSeq(s.toString("utf8",l+4,l+4+d-1)),g=s.readInt32LE(l+d+4);if(u[p]=h,f.push({refName:p,length:g}),l=l+8+d,l>s.length)return console.warn(`BAM header is very big. Re-fetching ${n} bytes.`),this._readRefSeqs(t,n*2,r)}return{chrToIndex:u,indexToChr:f}}async getRecordsForRange(t,n,r,i){return KK(this.streamRecordsForRange(t,n,r,i))}async*streamRecordsForRange(t,n,r,i){var a;await this.getHeader(i);const o=(a=this.chrToIndex)===null||a===void 0?void 0:a[t];if(o===void 0||!this.index)yield[];else{const s=await this.index.blocksForRange(o,n-1,r,i);yield*this._fetchChunkFeatures(s,o,n,r,i)}}async*_fetchChunkFeatures(t,n,r,i,a={}){const{viewAsPairs:o}=a,s=[];let c=!1;for(const l of t){const u=await this.featureCache.get(l.toString(),{chunk:l,opts:a},a.signal),f=[];for(const h of u)if(h.seq_id()===n)if(h.get("start")>=i){c=!0;break}else h.get("end")>=r&&f.push(h);if(s.push(f),yield f,c)break}NK(a.signal),o&&(yield this.fetchPairs(n,s,a))}async fetchPairs(t,n,r){const{pairAcrossChr:i,maxInsertSize:a=2e5}=r,o={},s={};n.map(h=>{const d={};for(const p of h){const g=p.name(),b=p.id();d[g]||(d[g]=0),d[g]++,s[b]=1}for(const[p,g]of Object.entries(d))g===1&&(o[p]=!0)});const c=[];n.map(h=>{for(const d of h){const p=d.name(),g=d.get("start"),b=d._next_pos(),y=d._next_refid();this.index&&o[p]&&(i||y===t&&Math.abs(g-b)<a)&&c.push(this.index.blocksForRange(y,b,b+1,r))}});const l=new Map,u=await Promise.all(c);for(const h of u.flat())l.has(h.toString())||l.set(h.toString(),h);return(await Promise.all([...l.values()].map(async h=>{const{data:d,cpositions:p,dpositions:g,chunk:b}=await this._readChunk({chunk:h,opts:r}),y=[];for(const w of await this.readBamFeatures(d,p,g,b))o[w.get("name")]&&!s[w.id()]&&y.push(w);return y}))).flat()}async _readRegion(t,n,r={}){const{bytesRead:i,buffer:a}=await this.bam.read(we.Buffer.alloc(n),0,n,t,r);return a.subarray(0,Math.min(i,n))}async _readChunk({chunk:t,opts:n}){const r=await this._readRegion(t.minv.blockPosition,t.fetchedSize(),n),{buffer:i,cpositions:a,dpositions:o}=await jC(r,t);return{data:i,cpositions:a,dpositions:o,chunk:t}}async readBamFeatures(t,n,r,i){let a=0;const o=[];let s=0,c=+Date.now();for(;a+4<t.length;){const l=t.readInt32LE(a),u=a+4+l-1;if(r){for(;a+i.minv.dataPosition>=r[s++];);s--}if(u<t.length){const f=new xk({bytes:{byteArray:t,start:a,end:u},fileOffset:n.length>0?n[s]*256+(a-r[s])+i.minv.dataPosition+1:YK.signed(t.slice(a,u))});o.push(f),this.yieldThreadTime&&+Date.now()-c>this.yieldThreadTime&&(await OK(1),c=+Date.now())}a=u+1}return o}async hasRefSeq(t){var n,r;const i=(n=this.chrToIndex)===null||n===void 0?void 0:n[t];return i===void 0?!1:(r=this.index)===null||r===void 0?void 0:r.hasRefSeq(i)}async lineCount(t){var n;const r=(n=this.chrToIndex)===null||n===void 0?void 0:n[t];return r===void 0||!this.index?0:this.index.lineCount(r)}async indexCov(t,n,r){var i;if(!this.index)return[];await this.index.parse();const a=(i=this.chrToIndex)===null||i===void 0?void 0:i[t];return a===void 0?[]:this.index.indexCov(a,n,r)}async blocksForRange(t,n,r,i){var a;if(!this.index)return[];await this.index.parse();const o=(a=this.chrToIndex)===null||a===void 0?void 0:a[t];return o===void 0?[]:this.index.blocksForRange(o,n,r,i)}}async function Ck(e,t){const n=await Promise.all(e.map(async r=>{const{url:i,headers:a}=r;if(i.startsWith("data:"))return we.Buffer.from(i.split(",")[1],"base64");{const{referer:o,...s}=a,c=await fetch(i,{...t,headers:{...t==null?void 0:t.headers,...s}});if(!c.ok)throw new Error(`HTTP ${c.status} fetching ${i}: ${await c.text()}`);return we.Buffer.from(await c.arrayBuffer())}}));return we.Buffer.concat(await Promise.all(n.map(r=>ea(r))))}class eJ extends _k{constructor(t){super({htsget:!0}),this.baseUrl=t.baseUrl,this.trackId=t.trackId}async*streamRecordsForRange(t,n,r,i){var a;const s=`${`${this.baseUrl}/${this.trackId}`}?referenceName=${t}&start=${n}&end=${r}&format=BAM`,c=(a=this.chrToIndex)===null||a===void 0?void 0:a[t];if(c===void 0)yield[];else{const l=await fetch(s,{...i});if(!l.ok)throw new Error(`HTTP ${l.status} fetching ${s}: ${await l.text()}`);const u=await l.json(),f=await Ck(u.htsget.urls.slice(1),i);yield*this._fetchChunkFeatures([{buffer:f,_fetchedSize:void 0,bin:0,compareTo(){return 0},toUniqueString(){return`${t}_${n}_${r}`},fetchedSize(){return 0},minv:{dataPosition:0,blockPosition:0,compareTo:()=>0},maxv:{dataPosition:Number.MAX_SAFE_INTEGER,blockPosition:0,compareTo:()=>0},toString(){return`${t}_${n}_${r}`}}],c,n,r,i)}}async _readChunk({chunk:t}){if(!t.buffer)throw new Error("expected chunk.buffer in htsget");return{data:t.buffer,cpositions:[],dpositions:[],chunk:t}}async getHeader(t={}){const n=`${this.baseUrl}/${this.trackId}?referenceName=na&class=header`,r=await fetch(n,t);if(!r.ok)throw new Error(`HTTP ${r.status} fetching ${n}: ${await r.text()}`);const i=await r.json(),a=await Ck(i.htsget.urls,t);if(a.readInt32LE(0)!==Ek)throw new Error("Not a BAM file");const o=a.readInt32LE(4),s=a.toString("utf8",8,8+o),c=Ak(s),l=[],u={},f=c.filter(h=>h.tag==="SQ");for(const[h,d]of f.entries()){let p="",g=0;for(const b of d.data)b.tag==="SN"?p=b.value:b.tag==="LN"&&(g=+b.value);u[p]=h,l[h]={refName:p,length:g}}return this.chrToIndex=u,this.indexToChr=l,c}}const tJ=Object.freeze(Object.defineProperty({__proto__:null,BAI:nc,BamFile:_k,BamRecord:xk,CSI:U0,HtsgetFile:eJ},Symbol.toStringTag,{value:"Module"}));function kk(e){if(e.greaterThan(Number.MAX_SAFE_INTEGER)||e.lessThan(Number.MIN_SAFE_INTEGER))throw new Error("integer overflow");return e.toNumber()}class nJ extends Error{}function rc(e){if(e&&e.aborted){if(typeof DOMException<"u")throw new DOMException("aborted","AbortError");{const t=new nJ("aborted");throw t.code="ERR_ABORTED",t}}}function rJ(e,t){return t.minv.blockPosition-e.maxv.blockPosition<65e3&&t.maxv.blockPosition-e.minv.blockPosition<5e6}function Tk(e,t){const n=[];let r=null;return e.length===0?e:(e.sort(function(i,a){const o=i.minv.blockPosition-a.minv.blockPosition;return o!==0?o:i.minv.dataPosition-a.minv.dataPosition}),e.forEach(i=>{(!t||i.maxv.compareTo(t)>0)&&(r===null?(n.push(i),r=i):rJ(r,i)?i.maxv.compareTo(r.maxv)>0&&(r.maxv=i.maxv):(n.push(i),r=i))}),n)}class p2{constructor(t,n){this.blockPosition=t,this.dataPosition=n}toString(){return`${this.blockPosition}:${this.dataPosition}`}compareTo(t){return this.blockPosition-t.blockPosition||this.dataPosition-t.dataPosition}static min(...t){let n,r=0;for(;!n;r+=1)n=t[r];for(;r<t.length;r+=1)n.compareTo(t[r])>0&&(n=t[r]);return n}}function ic(e,t=0,n=!1){if(n)throw new Error("big-endian virtual file offsets not implemented");return new p2(e[t+7]*1099511627776+e[t+6]*4294967296+e[t+5]*16777216+e[t+4]*65536+e[t+3]*256+e[t+2],e[t+1]<<8|e[t])}class $0{constructor(t,n,r,i=void 0){this.minv=t,this.maxv=n,this.bin=r,this._fetchedSize=i}toUniqueString(){return`${this.minv}..${this.maxv} (bin ${this.bin}, fetchedSize ${this.fetchedSize()})`}toString(){return this.toUniqueString()}compareTo(t){return this.minv.compareTo(t.minv)||this.maxv.compareTo(t.maxv)||this.bin-t.bin}fetchedSize(){return this._fetchedSize!==void 0?this._fetchedSize:this.maxv.blockPosition+65536-this.minv.blockPosition}}class Ik{constructor({filehandle:t,renameRefSeqs:n=r=>r}){this.filehandle=t,this.renameRefSeq=n}async getMetadata(t={}){const{indices:n,...r}=await this.parse(t);return r}_findFirstData(t,n){return t?t.compareTo(n)>0?n:t:n}async parse(t={}){return this.parseP||(this.parseP=this._parse(t).catch(n=>{throw this.parseP=void 0,n})),this.parseP}async hasRefSeq(t,n={}){var r;return!!(!((r=(await this.parse(n)).indices[t])===null||r===void 0)&&r.binIndex)}}const iJ=21578324,Rk=14;function aJ(e,t){return e+=1,t-=1,[[0,0],[1+(e>>26),1+(t>>26)],[9+(e>>23),9+(t>>23)],[73+(e>>20),73+(t>>20)],[585+(e>>17),585+(t>>17)],[4681+(e>>14),4681+(t>>14)]]}class H0 extends Ik{async lineCount(t,n={}){const r=await this.parse(n);if(!r)return-1;const i=r.refNameToId[t];if(!r.indices[i])return-1;const{stats:o}=r.indices[i];return o?o.lineCount:-1}async _parse(t={}){const n=await this.filehandle.readFile(t),r=await ea(n);if(rc(t.signal),r.readUInt32LE(0)!==iJ)throw new Error("Not a TBI file");const i=r.readInt32LE(4),a=r.readInt32LE(8),o=a&65536?"zero-based-half-open":"1-based-closed",c={0:"generic",1:"SAM",2:"VCF"}[a&15];if(!c)throw new Error(`invalid Tabix preset format flags ${a}`);const l={ref:r.readInt32LE(12),start:r.readInt32LE(16),end:r.readInt32LE(20)},u=r.readInt32LE(24),f=5,h=((1<<(f+1)*3)-1)/7,d=2**(14+f*3),p=u?String.fromCharCode(u):null,g=r.readInt32LE(28),b=r.readInt32LE(32),{refNameToId:y,refIdToName:w}=this._parseNameBytes(r.slice(36,36+b));let A=36+b,x;return{indices:new Array(i).fill(0).map(()=>{const _=r.readInt32LE(A);A+=4;const I={};let D;for(let O=0;O<_;O+=1){const ae=r.readUInt32LE(A);if(A+=4,ae>h+1)throw new Error("tabix index contains too many bins, please use a CSI index");if(ae===h+1){const se=r.readInt32LE(A);A+=4,se===2&&(D=this.parsePseudoBin(r,A)),A+=16*se}else{const se=r.readInt32LE(A);A+=4;const ve=new Array(se);for(let Pe=0;Pe<se;Pe+=1){const st=ic(r,A),Ne=ic(r,A+8);A+=16,x=this._findFirstData(x,st),ve[Pe]=new $0(st,Ne,ae)}I[ae]=ve}}const M=r.readInt32LE(A);A+=4;const G=new Array(M);for(let O=0;O<M;O+=1)G[O]=ic(r,A),A+=8,x=this._findFirstData(x,G[O]);return{binIndex:I,linearIndex:G,stats:D}}),metaChar:p,maxBinNumber:h,maxRefLength:d,skipLines:g,firstDataLine:x,columnNumbers:l,coordinateType:o,format:c,refIdToName:w,refNameToId:y,maxBlockSize:65536}}parsePseudoBin(t,n){return{lineCount:kk(p0.fromBytesLE(t.slice(n+16,n+24),!0))}}_parseNameBytes(t){let n=0,r=0;const i=[],a={};for(let o=0;o<t.length;o+=1)if(!t[o]){if(r<o){let s=t.toString("utf8",r,o);s=this.renameRefSeq(s),i[n]=s,a[s]=n}r=o+1,n+=1}return{refNameToId:a,refIdToName:i}}async blocksForRange(t,n,r,i={}){n<0&&(n=0);const a=await this.parse(i);if(!a)return[];const o=a.refNameToId[t],s=a.indices[o];if(!s)return[];(s.linearIndex.length?s.linearIndex[n>>Rk>=s.linearIndex.length?s.linearIndex.length-1:n>>Rk]:new p2(0,0))||console.warn("querying outside of possible tabix range");const l=aJ(n,r),u=[];for(const[g,b]of l)for(let y=g;y<=b;y++)if(s.binIndex[y])for(const w of s.binIndex[y])u.push(new $0(w.minv,w.maxv,y));const f=s.linearIndex.length;let h=null;const d=Math.min(n>>14,f-1),p=Math.min(r>>14,f-1);for(let g=d;g<=p;++g){const b=s.linearIndex[g];b&&(!h||b.compareTo(h)<0)&&(h=b)}return Tk(u,h)}}const oJ=21582659,sJ=38359875;function cJ(e,t){return e*2**t}function Dk(e,t){return Math.floor(e/2**t)}class g2 extends Ik{constructor(t){super(t),this.maxBinNumber=0,this.depth=0,this.minShift=0}async lineCount(t,n={}){const r=await this.parse(n);if(!r)return-1;const i=r.refNameToId[t];if(!r.indices[i])return-1;const{stats:o}=r.indices[i];return o?o.lineCount:-1}indexCov(){throw new Error("CSI indexes do not support indexcov")}parseAuxData(t,n){const r=t.readInt32LE(n),i=r&65536?"zero-based-half-open":"1-based-closed",a={0:"generic",1:"SAM",2:"VCF"}[r&15];if(!a)throw new Error(`invalid Tabix preset format flags ${r}`);const o={ref:t.readInt32LE(n+4),start:t.readInt32LE(n+8),end:t.readInt32LE(n+12)},s=t.readInt32LE(n+16),c=s?String.fromCharCode(s):null,l=t.readInt32LE(n+20),u=t.readInt32LE(n+24),{refIdToName:f,refNameToId:h}=this._parseNameBytes(t.slice(n+28,n+28+u));return{refIdToName:f,refNameToId:h,skipLines:l,metaChar:c,columnNumbers:o,format:a,coordinateType:i}}_parseNameBytes(t){let n=0,r=0;const i=[],a={};for(let o=0;o<t.length;o+=1)if(!t[o]){if(r<o){let s=t.toString("utf8",r,o);s=this.renameRefSeq(s),i[n]=s,a[s]=n}r=o+1,n+=1}return{refNameToId:a,refIdToName:i}}async _parse(t={}){const n=await ea(await this.filehandle.readFile(t));let r;if(n.readUInt32LE(0)===oJ)r=1;else if(n.readUInt32LE(0)===sJ)r=2;else throw new Error("Not a CSI file");this.minShift=n.readInt32LE(4),this.depth=n.readInt32LE(8),this.maxBinNumber=((1<<(this.depth+1)*3)-1)/7;const i=2**(this.minShift+this.depth*3),a=n.readInt32LE(12),o=a&&a>=30?this.parseAuxData(n,16):{refIdToName:[],refNameToId:{},metaChar:null,columnNumbers:{ref:0,start:1,end:2},coordinateType:"zero-based-half-open",format:"generic"},s=n.readInt32LE(16+a);let c,l=16+a+4;const u=new Array(s).fill(0).map(()=>{const f=n.readInt32LE(l);l+=4;const h={};let d;for(let p=0;p<f;p+=1){const g=n.readUInt32LE(l);if(g>this.maxBinNumber)d=this.parsePseudoBin(n,l+4),l+=4+8+4+16+16;else{const b=ic(n,l+4);c=this._findFirstData(c,b);const y=n.readInt32LE(l+12);l+=16;const w=new Array(y);for(let A=0;A<y;A+=1){const x=ic(n,l),C=ic(n,l+8);l+=16,w[A]=new $0(x,C,g)}h[g]=w}}return{binIndex:h,stats:d}});return{...o,csi:!0,refCount:s,maxBlockSize:65536,firstDataLine:c,csiVersion:r,indices:u,depth:this.depth,maxBinNumber:this.maxBinNumber,maxRefLength:i}}parsePseudoBin(t,n){return{lineCount:kk(p0.fromBytesLE(t.slice(n+28,n+36),!0))}}async blocksForRange(t,n,r,i={}){n<0&&(n=0);const a=await this.parse(i);if(!a)return[];const o=a.refNameToId[t],s=a.indices[o];if(!s)return[];const c=this.reg2bins(n,r),l=[];for(const[u,f]of c)for(let h=u;h<=f;h++)if(s.binIndex[h])for(const d of s.binIndex[h])l.push(new $0(d.minv,d.maxv,h));return Tk(l,new p2(0,0))}reg2bins(t,n){t-=1,t<1&&(t=1),n>2**50&&(n=2**34),n-=1;let r=0,i=0,a=this.minShift+this.depth*3;const o=[];for(;r<=this.depth;a-=3,i+=cJ(1,r*3),r+=1){const s=i+Dk(t,a),c=i+Dk(n,a);if(c-s+o.length>this.maxBinNumber)throw new Error(`query ${t}-${n} is too large for current binning scheme (shift ${this.minShift}, depth ${this.depth}), try a smaller query or a coarser index binning scheme`);o.push([s,c])}return o}}const m2=typeof TextDecoder<"u"?new TextDecoder("utf8"):void 0;function lJ(e){return new Promise(t=>setTimeout(t,e))}class uJ{constructor({path:t,filehandle:n,tbiPath:r,tbiFilehandle:i,csiPath:a,csiFilehandle:o,yieldTime:s=500,chunkSizeLimit:c=5e7,renameRefSeqs:l=f=>f,chunkCacheSize:u=5*2**20}){if(n)this.filehandle=n;else if(t)this.filehandle=new kt(t);else throw new TypeError("must provide either filehandle or path");if(i)this.index=new H0({filehandle:i,renameRefSeqs:l});else if(o)this.index=new g2({filehandle:o,renameRefSeqs:l});else if(r)this.index=new H0({filehandle:new kt(r),renameRefSeqs:l});else if(a)this.index=new g2({filehandle:new kt(a),renameRefSeqs:l});else if(t)this.index=new H0({filehandle:new kt(`${t}.tbi`),renameRefSeqs:l});else throw new TypeError("must provide one of tbiFilehandle, tbiPath, csiFilehandle, or csiPath");this.chunkSizeLimit=c,this.renameRefSeq=l,this.yieldTime=s,this.chunkCache=new A0({cache:new E0({maxSize:Math.floor(u/65536)}),fill:(f,h)=>this.readChunk(f,{signal:h})})}async getLines(t,n,r,i){var a;let o,s={},c;if(i===void 0)throw new TypeError("line callback must be provided");if(typeof i=="function"?c=i:(s=i,c=i.lineCallback,o=i.signal),t===void 0)throw new TypeError("must provide a reference sequence name");if(!c)throw new TypeError("line callback must be provided");const l=await this.index.getMetadata(s);rc(o);const u=n??0,f=r??l.maxRefLength;if(!(u<=f))throw new TypeError("invalid start and end coordinates. start must be less than or equal to end");if(u===f)return;const h=await this.index.blocksForRange(t,u,f,s);rc(o);for(const p of h){const g=p.fetchedSize();if(g>this.chunkSizeLimit)throw new Error(`Too much data. Chunk size ${g.toLocaleString()} bytes exceeds chunkSizeLimit of ${this.chunkSizeLimit.toLocaleString()}.`)}let d=Date.now();for(const p of h){let g;const{buffer:b,cpositions:y,dpositions:w}=await this.chunkCache.get(p.toString(),p,o);rc(o);let A=0,x=0;for(;A<b.length;){const C=b.indexOf(`
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`,A);if(C===-1)break;const _=b.slice(A,C),I=(a=m2==null?void 0:m2.decode(_))!==null&&a!==void 0?a:_.toString();if(w){for(;A+p.minv.dataPosition>=w[x++];);x--}const{startCoordinate:D,overlaps:M}=this.checkLine(l,t,u,f,I);if(g!==void 0&&D!==void 0&&g>D)throw new Error(`Lines not sorted by start coordinate (${g} > ${D}), this file is not usable with Tabix.`);if(g=D,M)c(I.trim(),y[x]*256+(A-w[x])+p.minv.dataPosition+1);else if(D!==void 0&&D>=f)return;this.yieldTime&&d-Date.now()>this.yieldTime&&(d=Date.now(),rc(o),await
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3438
|
-
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0?".":mT(e.attributes),i=`${[e.seq_id===null?".":ii(e.seq_id),e.source===null?".":ii(e.source),e.type===null?".":ii(e.type),e.start===null?".":ii(e.start),e.end===null?".":ii(e.end),e.score===null?".":ii(e.score),e.strand===null?".":ii(e.strand),e.phase===null?".":ii(e.phase),n].join(" ")}
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)`},Symbol.toStringTag,{value:"Module"}))).map(([e,t])=>[e,hk.parse(t.trim())]));function u2(e){const t=["uint","int","float","long"];return{...e,fields:e.fields.map(n=>({...n,isArray:n.size&&n.type!=="char",arrayIsNumeric:n.size&&t.includes(n.type),isNumeric:!n.size&&t.includes(n.type)}))}}const FK={".":0,"-":-1,"+":1};function PK(e){var t;return e.length>=12&&!Number.isNaN(parseInt(e[9],10))&&((t=e[10])===null||t===void 0?void 0:t.split(",").filter(n=>!!n).length)===parseInt(e[9],10)}class MK{constructor(t={}){if(t.autoSql)this.autoSql=u2(BK.parse(t.autoSql));else if(t.type){if(!l2[t.type])throw new Error("Type not found");this.autoSql=u2(l2[t.type])}else this.autoSql=u2(l2.defaultBedSchema),this.attemptDefaultBed=!0}parseLine(t,n={}){const{autoSql:r}=this,{uniqueId:i}=n,a=Array.isArray(t)?t:t.split(" ");let o={};if(!this.attemptDefaultBed||this.attemptDefaultBed&&PK(a))for(let s=0;s<r.fields.length;s++){const c=r.fields[s];let l=a[s];const{isNumeric:u,isArray:f,arrayIsNumeric:h,name:d}=c;if(l==null)break;if(l!=="."){if(u){const p=Number(l);l=Number.isNaN(p)?l:p}else f&&(l=l.split(","),l[l.length-1]===""&&l.pop(),h&&(l=l.map(p=>Number(p))));o[d]=l}}else{const s=["chrom","chromStart","chromEnd","name"];o=Object.fromEntries(a.map((c,l)=>[s[l]||"field"+l,c])),o.chromStart=+o.chromStart,o.chromEnd=+o.chromEnd,Number.isNaN(Number.parseFloat(o.field4))||(o.score=+o.field4,delete o.field4),(o.field5==="+"||o.field5==="-")&&(o.strand=o.field5,delete o.field5)}return i&&(o.uniqueId=i),o.strand=FK[o.strand]||0,o.chrom=decodeURIComponent(o.chrom),o}}const OK=Object.freeze(Object.defineProperty({__proto__:null,default:MK},Symbol.toStringTag,{value:"Module"}));let dk=class{constructor(t,n){this.blockPosition=t,this.dataPosition=n}toString(){return`${this.blockPosition}:${this.dataPosition}`}compareTo(t){return this.blockPosition-t.blockPosition||this.dataPosition-t.dataPosition}static min(...t){let n,r=0;for(;!n;r+=1)n=t[r];for(;r<t.length;r+=1)n.compareTo(t[r])>0&&(n=t[r]);return n}};function tc(e,t=0,n=!1){if(n)throw new Error("big-endian virtual file offsets not implemented");return new dk(e[t+7]*1099511627776+e[t+6]*4294967296+e[t+5]*16777216+e[t+4]*65536+e[t+3]*256+e[t+2],e[t+1]<<8|e[t])}let pk=class{constructor(t,n,r,i){this.minv=t,this.maxv=n,this.bin=r,this._fetchedSize=i}toUniqueString(){return`${this.minv}..${this.maxv} (bin ${this.bin}, fetchedSize ${this.fetchedSize()})`}toString(){return this.toUniqueString()}compareTo(t){return this.minv.compareTo(t.minv)||this.maxv.compareTo(t.maxv)||this.bin-t.bin}fetchedSize(){return this._fetchedSize!==void 0?this._fetchedSize:this.maxv.blockPosition+65536-this.minv.blockPosition}};function LK(e){return new Promise(t=>setTimeout(t,e))}function NK(e){if(e.greaterThan(Number.MAX_SAFE_INTEGER)||e.lessThan(Number.MIN_SAFE_INTEGER))throw new Error("integer overflow");return e.toNumber()}function zK(e){if(e&&e.aborted)if(typeof DOMException>"u"){const t=new Error("aborted");throw t.code="ERR_ABORTED",t}else throw new DOMException("aborted","AbortError")}function UK(e,t){return t.minv.blockPosition-e.maxv.blockPosition<65e3&&t.maxv.blockPosition-e.minv.blockPosition<5e6}function $K(e={}){return"aborted"in e?{signal:e}:e}function gk(e,t){const n=[];let r;if(e.length===0)return e;e.sort((i,a)=>{const o=i.minv.blockPosition-a.minv.blockPosition;return o===0?i.minv.dataPosition-a.minv.dataPosition:o});for(const i of e)(!t||i.maxv.compareTo(t)>0)&&(r===void 0?(n.push(i),r=i):UK(r,i)?i.maxv.compareTo(r.maxv)>0&&(r.maxv=i.maxv):(n.push(i),r=i));return n}function mk(e,t){return{lineCount:NK(p0.fromBytesLE(Array.prototype.slice.call(e,t,t+8),!0))}}function z0(e,t){return e?e.compareTo(t)>0?t:e:t}function HK(e,t=n=>n){let n=0,r=0;const i=[],a={};for(let o=0;o<e.length;o+=1)if(!e[o]){if(r<o){let s=e.toString("utf8",r,o);s=t(s),i[n]=s,a[s]=n}r=o+1,n+=1}return{refNameToId:a,refIdToName:i}}let bk=class{constructor({filehandle:t,renameRefSeq:n=r=>r}){this.filehandle=t,this.renameRefSeq=n}};const GK=21578050;function VK(e,t){return e-e%t}function jK(e,t){return e-e%t+t}function qK(e,t){return t-=1,[[0,0],[1+(e>>26),1+(t>>26)],[9+(e>>23),9+(t>>23)],[73+(e>>20),73+(t>>20)],[585+(e>>17),585+(t>>17)],[4681+(e>>14),4681+(t>>14)]]}class nc extends bk{async lineCount(t,n){var r,i;return((i=(r=(await this.parse(n)).indices[t])===null||r===void 0?void 0:r.stats)===null||i===void 0?void 0:i.lineCount)||0}async _parse(t){const n=await this.filehandle.readFile(t);if(n.readUInt32LE(0)!==GK)throw new Error("Not a BAI file");const r=n.readInt32LE(4),a=((1<<(5+1)*3)-1)/7;let o=8,s;const c=new Array(r);for(let l=0;l<r;l++){const u=n.readInt32LE(o);let f;o+=4;const h={};for(let g=0;g<u;g+=1){const b=n.readUInt32LE(o);if(o+=4,b===a+1)o+=4,f=mk(n,o+16),o+=32;else{if(b>a+1)throw new Error("bai index contains too many bins, please use CSI");{const y=n.readInt32LE(o);o+=4;const w=new Array(y);for(let A=0;A<y;A++){const x=tc(n,o);o+=8;const C=tc(n,o);o+=8,s=z0(s,x),w[A]=new pk(x,C,b)}h[b]=w}}}const d=n.readInt32LE(o);o+=4;const p=new Array(d);for(let g=0;g<d;g++){const b=tc(n,o);o+=8,s=z0(s,b),p[g]=b}c[l]={binIndex:h,linearIndex:p,stats:f}}return{bai:!0,firstDataLine:s,maxBlockSize:65536,indices:c,refCount:r}}async indexCov(t,n,r,i={}){const o=n!==void 0,c=(await this.parse(i)).indices[t];if(!c)return[];const{linearIndex:l=[],stats:u}=c;if(l.length===0)return[];const f=r===void 0?(l.length-1)*16384:jK(r,16384),h=n===void 0?0:VK(n,16384),d=o?new Array((f-h)/16384):new Array(l.length-1),p=l[l.length-1].blockPosition;if(f>(l.length-1)*16384)throw new Error("query outside of range of linear index");let g=l[h/16384].blockPosition;for(let b=h/16384,y=0;b<f/16384;b++,y++)d[y]={score:l[b+1].blockPosition-g,start:b*16384,end:b*16384+16384},g=l[b+1].blockPosition;return d.map(b=>({...b,score:b.score*((u==null?void 0:u.lineCount)||0)/p}))}async blocksForRange(t,n,r,i={}){n<0&&(n=0);const a=await this.parse(i);if(!a)return[];const o=a.indices[t];if(!o)return[];const s=qK(n,r),c=[];for(const[d,p]of s)for(let g=d;g<=p;g++)if(o.binIndex[g]){const b=o.binIndex[g];for(const y of b)c.push(y)}const l=o.linearIndex.length;let u;const f=Math.min(n>>14,l-1),h=Math.min(r>>14,l-1);for(let d=f;d<=h;++d){const p=o.linearIndex[d];p&&(!u||p.compareTo(u)<0)&&(u=p)}return gk(c,u)}async parse(t={}){return this.setupP||(this.setupP=this._parse(t).catch(n=>{throw this.setupP=void 0,n})),this.setupP}async hasRefSeq(t,n={}){var r;return!!(!((r=(await this.parse(n)).indices[t])===null||r===void 0)&&r.binIndex)}}var ca=we.Buffer,f2=[0,1996959894,3993919788,2567524794,124634137,1886057615,3915621685,2657392035,249268274,2044508324,3772115230,2547177864,162941995,2125561021,3887607047,2428444049,498536548,1789927666,4089016648,2227061214,450548861,1843258603,4107580753,2211677639,325883990,1684777152,4251122042,2321926636,335633487,1661365465,4195302755,2366115317,997073096,1281953886,3579855332,2724688242,1006888145,1258607687,3524101629,2768942443,901097722,1119000684,3686517206,2898065728,853044451,1172266101,3705015759,2882616665,651767980,1373503546,3369554304,3218104598,565507253,1454621731,3485111705,3099436303,671266974,1594198024,3322730930,2970347812,795835527,1483230225,3244367275,3060149565,1994146192,31158534,2563907772,4023717930,1907459465,112637215,2680153253,3904427059,2013776290,251722036,2517215374,3775830040,2137656763,141376813,2439277719,3865271297,1802195444,476864866,2238001368,4066508878,1812370925,453092731,2181625025,4111451223,1706088902,314042704,2344532202,4240017532,1658658271,366619977,2362670323,4224994405,1303535960,984961486,2747007092,3569037538,1256170817,1037604311,2765210733,3554079995,1131014506,879679996,2909243462,3663771856,1141124467,855842277,2852801631,3708648649,1342533948,654459306,3188396048,3373015174,1466479909,544179635,3110523913,3462522015,1591671054,702138776,2966460450,3352799412,1504918807,783551873,3082640443,3233442989,3988292384,2596254646,62317068,1957810842,3939845945,2647816111,81470997,1943803523,3814918930,2489596804,225274430,2053790376,3826175755,2466906013,167816743,2097651377,4027552580,2265490386,503444072,1762050814,4150417245,2154129355,426522225,1852507879,4275313526,2312317920,282753626,1742555852,4189708143,2394877945,397917763,1622183637,3604390888,2714866558,953729732,1340076626,3518719985,2797360999,1068828381,1219638859,3624741850,2936675148,906185462,1090812512,3747672003,2825379669,829329135,1181335161,3412177804,3160834842,628085408,1382605366,3423369109,3138078467,570562233,1426400815,3317316542,2998733608,733239954,1555261956,3268935591,3050360625,752459403,1541320221,2607071920,3965973030,1969922972,40735498,2617837225,3943577151,1913087877,83908371,2512341634,3803740692,2075208622,213261112,2463272603,3855990285,2094854071,198958881,2262029012,4057260610,1759359992,534414190,2176718541,4139329115,1873836001,414664567,2282248934,4279200368,1711684554,285281116,2405801727,4167216745,1634467795,376229701,2685067896,3608007406,1308918612,956543938,2808555105,3495958263,1231636301,1047427035,2932959818,3654703836,1088359270,936918e3,2847714899,3736837829,1202900863,817233897,3183342108,3401237130,1404277552,615818150,3134207493,3453421203,1423857449,601450431,3009837614,3294710456,1567103746,711928724,3020668471,3272380065,1510334235,755167117];typeof Int32Array<"u"&&(f2=new Int32Array(f2));function yk(e){if(ca.isBuffer(e))return e;var t=typeof ca.alloc=="function"&&typeof ca.from=="function";if(typeof e=="number")return t?ca.alloc(e):new ca(e);if(typeof e=="string")return t?ca.from(e):new ca(e);throw new Error("input must be buffer, number, or string, received "+typeof e)}function WK(e){var t=yk(4);return t.writeInt32BE(e,0),t}function h2(e,t){e=yk(e),ca.isBuffer(t)&&(t=t.readUInt32BE(0));for(var n=~~t^-1,r=0;r<e.length;r++)n=f2[(n^e[r])&255]^n>>>8;return n^-1}function d2(){return WK(h2.apply(null,arguments))}d2.signed=function(){return h2.apply(null,arguments)},d2.unsigned=function(){return h2.apply(null,arguments)>>>0};var YK=d2;const ZK=uu(YK),QK=21582659,XK=38359875;function KK(e,t){return e*2**t}function vk(e,t){return Math.floor(e/2**t)}let U0=class extends bk{constructor(){super(...arguments),this.maxBinNumber=0,this.depth=0,this.minShift=0}async lineCount(t,n){var r,i;return((i=(r=(await this.parse(n)).indices[t])===null||r===void 0?void 0:r.stats)===null||i===void 0?void 0:i.lineCount)||0}async indexCov(){return[]}parseAuxData(t,n){const r=t.readInt32LE(n),i=r&65536?"zero-based-half-open":"1-based-closed",a={0:"generic",1:"SAM",2:"VCF"}[r&15];if(!a)throw new Error(`invalid Tabix preset format flags ${r}`);const o={ref:t.readInt32LE(n+4),start:t.readInt32LE(n+8),end:t.readInt32LE(n+12)},s=t.readInt32LE(n+16),c=s?String.fromCharCode(s):"",l=t.readInt32LE(n+20),u=t.readInt32LE(n+24);return{columnNumbers:o,coordinateType:i,metaValue:s,metaChar:c,skipLines:l,format:a,formatFlags:r,...HK(t.subarray(n+28,n+28+u),this.renameRefSeq)}}async _parse(t){const n=await this.filehandle.readFile(t),r=await ea(n);let i;if(r.readUInt32LE(0)===QK)i=1;else if(r.readUInt32LE(0)===XK)i=2;else throw new Error("Not a CSI file");this.minShift=r.readInt32LE(4),this.depth=r.readInt32LE(8),this.maxBinNumber=((1<<(this.depth+1)*3)-1)/7;const a=r.readInt32LE(12),o=a>=30?this.parseAuxData(r,16):void 0,s=r.readInt32LE(16+a);let c=16+a+4,l;const u=new Array(s);for(let f=0;f<s;f++){const h=r.readInt32LE(c);c+=4;const d={};let p;for(let g=0;g<h;g++){const b=r.readUInt32LE(c);if(c+=4,b>this.maxBinNumber)p=mk(r,c+28),c+=28+16;else{l=z0(l,tc(r,c)),c+=8;const y=r.readInt32LE(c);c+=4;const w=new Array(y);for(let A=0;A<y;A+=1){const x=tc(r,c);c+=8;const C=tc(r,c);c+=8,l=z0(l,x),w[A]=new pk(x,C,b)}d[b]=w}}u[f]={binIndex:d,stats:p}}return{csiVersion:i,firstDataLine:l,indices:u,refCount:s,csi:!0,maxBlockSize:65536,...o}}async blocksForRange(t,n,r,i={}){n<0&&(n=0);const a=await this.parse(i),o=a==null?void 0:a.indices[t];if(!o)return[];const s=this.reg2bins(n,r);if(s.length===0)return[];const c=[];for(const[l,u]of s)for(let f=l;f<=u;f++)if(o.binIndex[f]){const h=o.binIndex[f];for(const d of h)c.push(d)}return gk(c,new dk(0,0))}reg2bins(t,n){t-=1,t<1&&(t=1),n>2**50&&(n=2**34),n-=1;let r=0,i=0,a=this.minShift+this.depth*3;const o=[];for(;r<=this.depth;a-=3,i+=KK(1,r*3),r+=1){const s=i+vk(t,a),c=i+vk(n,a);if(c-s+o.length>this.maxBinNumber)throw new Error(`query ${t}-${n} is too large for current binning scheme (shift ${this.minShift}, depth ${this.depth}), try a smaller query or a coarser index binning scheme`);o.push([s,c])}return o}async parse(t={}){return this.setupP||(this.setupP=this._parse(t).catch(n=>{throw this.setupP=void 0,n})),this.setupP}async hasRefSeq(t,n={}){var r;return!!(!((r=(await this.parse(n)).indices[t])===null||r===void 0)&&r.binIndex)}};const Mn={BAM_FPAIRED:1,BAM_FPROPER_PAIR:2,BAM_FUNMAP:4,BAM_FMUNMAP:8,BAM_FREVERSE:16,BAM_FMREVERSE:32,BAM_FREAD1:64,BAM_FREAD2:128,BAM_FSECONDARY:256,BAM_FQCFAIL:512,BAM_FDUP:1024,BAM_FSUPPLEMENTARY:2048},wk="=ACMGRSVTWYHKDBN".split(""),Xu="MIDNSHP=X???????".split("");class xk{constructor(t){this.data={},this._tagList=[],this._allTagsParsed=!1;const{bytes:n,fileOffset:r}=t,{byteArray:i,start:a}=n;this.data={},this.bytes=n,this._id=r,this._refID=i.readInt32LE(a+4),this.data.start=i.readInt32LE(a+8),this.flags=(i.readInt32LE(a+16)&4294901760)>>16}get(t){return this[t]?this.data[t]?this.data[t]:(this.data[t]=this[t](),this.data[t]):this._get(t.toLowerCase())}end(){return this.get("start")+this.get("length_on_ref")}seq_id(){return this._refID}_get(t){return t in this.data?this.data[t]:(this.data[t]=this._parseTag(t),this.data[t])}_tags(){this._parseAllTags();let t=["seq"];this.isSegmentUnmapped()||t.push("start","end","strand","score","qual","MQ","CIGAR","length_on_ref","template_length"),this.isPaired()&&t.push("next_segment_position","pair_orientation"),t=t.concat(this._tagList||[]);for(const r of Object.keys(this.data))r[0]!=="_"&&r!=="next_seq_id"&&t.push(r);const n={};return t.filter(r=>{if(r in this.data&&this.data[r]===void 0||r==="CG"||r==="cg")return!1;const i=r.toLowerCase(),a=n[i];return n[i]=!0,!a})}parent(){}children(){return this.get("subfeatures")}id(){return this._id}mq(){const t=(this.get("_bin_mq_nl")&65280)>>8;return t===255?void 0:t}score(){return this.get("mq")}qual(){var t;return(t=this.qualRaw())===null||t===void 0?void 0:t.join(" ")}qualRaw(){if(this.isSegmentUnmapped())return;const{start:t,byteArray:n}=this.bytes,r=t+36+this.get("_l_read_name")+this.get("_n_cigar_op")*4+this.get("_seq_bytes"),i=this.get("seq_length");return n.subarray(r,r+i)}strand(){return this.isReverseComplemented()?-1:1}multi_segment_next_segment_strand(){if(!this.isMateUnmapped())return this.isMateReverseComplemented()?-1:1}name(){return this.get("_read_name")}_read_name(){const t=this.get("_l_read_name"),{byteArray:n,start:r}=this.bytes;return n.toString("ascii",r+36,r+36+t-1)}_parseTag(t){if(this._allTagsParsed)return;const{byteArray:n,start:r}=this.bytes;let i=this._tagOffset||r+36+this.get("_l_read_name")+this.get("_n_cigar_op")*4+this.get("_seq_bytes")+this.get("seq_length");const a=this.bytes.end;let o;for(;i<a&&o!==t;){const s=String.fromCharCode(n[i],n[i+1]);o=s.toLowerCase();const c=String.fromCharCode(n[i+2]);i+=3;let l;switch(c){case"A":{l=String.fromCharCode(n[i]),i+=1;break}case"i":{l=n.readInt32LE(i),i+=4;break}case"I":{l=n.readUInt32LE(i),i+=4;break}case"c":{l=n.readInt8(i),i+=1;break}case"C":{l=n.readUInt8(i),i+=1;break}case"s":{l=n.readInt16LE(i),i+=2;break}case"S":{l=n.readUInt16LE(i),i+=2;break}case"f":{l=n.readFloatLE(i),i+=4;break}case"Z":case"H":{for(l="";i<=a;){const u=n[i++];if(u===0)break;l+=String.fromCharCode(u)}break}case"B":{l="";const u=n[i++],f=String.fromCharCode(u),h=n.readInt32LE(i);if(i+=4,f==="i")if(s==="CG")for(let d=0;d<h;d++){const p=n.readInt32LE(i),g=p>>4,b=Xu[p&15];l+=g+b,i+=4}else for(let d=0;d<h;d++)l+=n.readInt32LE(i),d+1<h&&(l+=","),i+=4;if(f==="I")if(s==="CG")for(let d=0;d<h;d++){const p=n.readUInt32LE(i),g=p>>4,b=Xu[p&15];l+=g+b,i+=4}else for(let d=0;d<h;d++)l+=n.readUInt32LE(i),d+1<h&&(l+=","),i+=4;if(f==="s")for(let d=0;d<h;d++)l+=n.readInt16LE(i),d+1<h&&(l+=","),i+=2;if(f==="S")for(let d=0;d<h;d++)l+=n.readUInt16LE(i),d+1<h&&(l+=","),i+=2;if(f==="c")for(let d=0;d<h;d++)l+=n.readInt8(i),d+1<h&&(l+=","),i+=1;if(f==="C")for(let d=0;d<h;d++)l+=n.readUInt8(i),d+1<h&&(l+=","),i+=1;if(f==="f")for(let d=0;d<h;d++)l+=n.readFloatLE(i),d+1<h&&(l+=","),i+=4;break}default:console.warn(`Unknown BAM tag type '${c}', tags may be incomplete`),l=void 0,i=a}if(this._tagOffset=i,this._tagList.push(s),o===t)return l;this.data[o]=l}this._allTagsParsed=!0}_parseAllTags(){this._parseTag("")}_parseCigar(t){return t.match(/\d+\D/g).map(n=>[n.match(/\D/)[0].toUpperCase(),Number.parseInt(n,10)])}isPaired(){return!!(this.flags&Mn.BAM_FPAIRED)}isProperlyPaired(){return!!(this.flags&Mn.BAM_FPROPER_PAIR)}isSegmentUnmapped(){return!!(this.flags&Mn.BAM_FUNMAP)}isMateUnmapped(){return!!(this.flags&Mn.BAM_FMUNMAP)}isReverseComplemented(){return!!(this.flags&Mn.BAM_FREVERSE)}isMateReverseComplemented(){return!!(this.flags&Mn.BAM_FMREVERSE)}isRead1(){return!!(this.flags&Mn.BAM_FREAD1)}isRead2(){return!!(this.flags&Mn.BAM_FREAD2)}isSecondary(){return!!(this.flags&Mn.BAM_FSECONDARY)}isFailedQc(){return!!(this.flags&Mn.BAM_FQCFAIL)}isDuplicate(){return!!(this.flags&Mn.BAM_FDUP)}isSupplementary(){return!!(this.flags&Mn.BAM_FSUPPLEMENTARY)}cigar(){if(this.isSegmentUnmapped())return;const{byteArray:t,start:n}=this.bytes,r=this.get("_n_cigar_op");let i=n+36+this.get("_l_read_name");const a=this.get("seq_length");let o="",s=0,c=t.readInt32LE(i),l=c>>4,u=Xu[c&15];if(u==="S"&&l===a)return i+=4,c=t.readInt32LE(i),l=c>>4,u=Xu[c&15],u!=="N"&&console.warn("CG tag with no N tag"),this.data.length_on_ref=l,this.get("CG");for(let f=0;f<r;++f)c=t.readInt32LE(i),l=c>>4,u=Xu[c&15],o+=l+u,u!=="H"&&u!=="S"&&u!=="I"&&(s+=l),i+=4;return this.data.length_on_ref=s,o}_flags(){}length_on_ref(){return this.data.length_on_ref?this.data.length_on_ref:(this.get("cigar"),this.data.length_on_ref)}_n_cigar_op(){return this.get("_flag_nc")&65535}_l_read_name(){return this.get("_bin_mq_nl")&255}_seq_bytes(){return this.get("seq_length")+1>>1}getReadBases(){return this.seq()}seq(){const{byteArray:t,start:n}=this.bytes,r=n+36+this.get("_l_read_name")+this.get("_n_cigar_op")*4,i=this.get("_seq_bytes"),a=this.get("seq_length");let o="",s=0;for(let c=0;c<i;++c){const l=t[r+c];o+=wk[(l&240)>>4],s++,s<a&&(o+=wk[l&15],s++)}return o}getPairOrientation(){if(!this.isSegmentUnmapped()&&!this.isMateUnmapped()&&this._refID===this._next_refid()){const t=this.isReverseComplemented()?"R":"F",n=this.isMateReverseComplemented()?"R":"F";let r=" ",i=" ";this.isRead1()?(r="1",i="2"):this.isRead2()&&(r="2",i="1");const a=[];return this.template_length()>0?(a[0]=t,a[1]=r,a[2]=n,a[3]=i):(a[2]=t,a[3]=r,a[0]=n,a[1]=i),a.join("")}return""}_bin_mq_nl(){return this.bytes.byteArray.readInt32LE(this.bytes.start+12)}_flag_nc(){return this.bytes.byteArray.readInt32LE(this.bytes.start+16)}seq_length(){return this.bytes.byteArray.readInt32LE(this.bytes.start+20)}_next_refid(){return this.bytes.byteArray.readInt32LE(this.bytes.start+24)}_next_pos(){return this.bytes.byteArray.readInt32LE(this.bytes.start+28)}template_length(){return this.bytes.byteArray.readInt32LE(this.bytes.start+32)}toJSON(){const t={};for(const n of Object.keys(this))n.charAt(0)==="_"||n==="bytes"||(t[n]=this[n]);return t}}function Ak(e){const t=e.split(/\r?\n/),n=[];for(const r of t){const[i,...a]=r.split(/\t/);i&&n.push({tag:i.slice(1),data:a.map(o=>{const[s,c]=o.split(":",2);return{tag:s,value:c}})})}return n}const Ek=21840194,Sk=65536;async function JK(e){let t=[];for await(const n of e)t=t.concat(n);return t}class eJ{read(){throw new Error("never called")}stat(){throw new Error("never called")}readFile(){throw new Error("never called")}close(){throw new Error("never called")}}class _k{constructor({bamFilehandle:t,bamPath:n,bamUrl:r,baiPath:i,baiFilehandle:a,baiUrl:o,csiPath:s,csiFilehandle:c,csiUrl:l,htsget:u,yieldThreadTime:f=100,renameRefSeqs:h=d=>d}){if(this.htsget=!1,this.featureCache=new A0({cache:new E0({maxSize:50}),fill:async(d,p)=>{const{chunk:g,opts:b}=d,{data:y,cpositions:w,dpositions:A}=await this._readChunk({chunk:g,opts:{...b,signal:p}});return this.readBamFeatures(y,w,A,g)}}),this.renameRefSeq=h,t)this.bam=t;else if(n)this.bam=new kt(n);else if(r)this.bam=new po(r);else if(u)this.htsget=!0,this.bam=new eJ;else throw new Error("unable to initialize bam");if(c)this.index=new U0({filehandle:c});else if(s)this.index=new U0({filehandle:new kt(s)});else if(l)this.index=new U0({filehandle:new po(l)});else if(a)this.index=new nc({filehandle:a});else if(i)this.index=new nc({filehandle:new kt(i)});else if(o)this.index=new nc({filehandle:new po(o)});else if(n)this.index=new nc({filehandle:new kt(`${n}.bai`)});else if(r)this.index=new nc({filehandle:new po(`${r}.bai`)});else if(u)this.htsget=!0;else throw new Error("unable to infer index format");this.yieldThreadTime=f}async getHeaderPre(t){const n=$K(t);if(!this.index)return;const r=await this.index.parse(n),i=r.firstDataLine?r.firstDataLine.blockPosition+65535:void 0;let a;if(i){const u=i+Sk,f=await this.bam.read(we.Buffer.alloc(u),0,u,0,n);if(!f.bytesRead)throw new Error("Error reading header");a=f.buffer.subarray(0,Math.min(f.bytesRead,i))}else a=await this.bam.readFile(n);const o=await ea(a);if(o.readInt32LE(0)!==Ek)throw new Error("Not a BAM file");const s=o.readInt32LE(4);this.header=o.toString("utf8",8,8+s);const{chrToIndex:c,indexToChr:l}=await this._readRefSeqs(s+8,65535,n);return this.chrToIndex=c,this.indexToChr=l,Ak(this.header)}getHeader(t){return this.headerP||(this.headerP=this.getHeaderPre(t).catch(n=>{throw this.headerP=void 0,n})),this.headerP}async getHeaderText(t={}){return await this.getHeader(t),this.header}async _readRefSeqs(t,n,r){if(t>n)return this._readRefSeqs(t,n*2,r);const i=n+Sk,{bytesRead:a,buffer:o}=await this.bam.read(we.Buffer.alloc(i),0,n,0,r);if(!a)throw new Error("Error reading refseqs from header");const s=await ea(o.subarray(0,Math.min(a,n))),c=s.readInt32LE(t);let l=t+4;const u={},f=[];for(let h=0;h<c;h+=1){const d=s.readInt32LE(l),p=this.renameRefSeq(s.toString("utf8",l+4,l+4+d-1)),g=s.readInt32LE(l+d+4);if(u[p]=h,f.push({refName:p,length:g}),l=l+8+d,l>s.length)return console.warn(`BAM header is very big. Re-fetching ${n} bytes.`),this._readRefSeqs(t,n*2,r)}return{chrToIndex:u,indexToChr:f}}async getRecordsForRange(t,n,r,i){return JK(this.streamRecordsForRange(t,n,r,i))}async*streamRecordsForRange(t,n,r,i){var a;await this.getHeader(i);const o=(a=this.chrToIndex)===null||a===void 0?void 0:a[t];if(o===void 0||!this.index)yield[];else{const s=await this.index.blocksForRange(o,n-1,r,i);yield*this._fetchChunkFeatures(s,o,n,r,i)}}async*_fetchChunkFeatures(t,n,r,i,a={}){const{viewAsPairs:o}=a,s=[];let c=!1;for(const l of t){const u=await this.featureCache.get(l.toString(),{chunk:l,opts:a},a.signal),f=[];for(const h of u)if(h.seq_id()===n)if(h.get("start")>=i){c=!0;break}else h.get("end")>=r&&f.push(h);if(s.push(f),yield f,c)break}zK(a.signal),o&&(yield this.fetchPairs(n,s,a))}async fetchPairs(t,n,r){const{pairAcrossChr:i,maxInsertSize:a=2e5}=r,o={},s={};n.map(h=>{const d={};for(const p of h){const g=p.name(),b=p.id();d[g]||(d[g]=0),d[g]++,s[b]=1}for(const[p,g]of Object.entries(d))g===1&&(o[p]=!0)});const c=[];n.map(h=>{for(const d of h){const p=d.name(),g=d.get("start"),b=d._next_pos(),y=d._next_refid();this.index&&o[p]&&(i||y===t&&Math.abs(g-b)<a)&&c.push(this.index.blocksForRange(y,b,b+1,r))}});const l=new Map,u=await Promise.all(c);for(const h of u.flat())l.has(h.toString())||l.set(h.toString(),h);return(await Promise.all([...l.values()].map(async h=>{const{data:d,cpositions:p,dpositions:g,chunk:b}=await this._readChunk({chunk:h,opts:r}),y=[];for(const w of await this.readBamFeatures(d,p,g,b))o[w.get("name")]&&!s[w.id()]&&y.push(w);return y}))).flat()}async _readRegion(t,n,r={}){const{bytesRead:i,buffer:a}=await this.bam.read(we.Buffer.alloc(n),0,n,t,r);return a.subarray(0,Math.min(i,n))}async _readChunk({chunk:t,opts:n}){const r=await this._readRegion(t.minv.blockPosition,t.fetchedSize(),n),{buffer:i,cpositions:a,dpositions:o}=await jC(r,t);return{data:i,cpositions:a,dpositions:o,chunk:t}}async readBamFeatures(t,n,r,i){let a=0;const o=[];let s=0,c=+Date.now();for(;a+4<t.length;){const l=t.readInt32LE(a),u=a+4+l-1;if(r){for(;a+i.minv.dataPosition>=r[s++];);s--}if(u<t.length){const f=new xk({bytes:{byteArray:t,start:a,end:u},fileOffset:n.length>0?n[s]*256+(a-r[s])+i.minv.dataPosition+1:ZK.signed(t.slice(a,u))});o.push(f),this.yieldThreadTime&&+Date.now()-c>this.yieldThreadTime&&(await LK(1),c=+Date.now())}a=u+1}return o}async hasRefSeq(t){var n,r;const i=(n=this.chrToIndex)===null||n===void 0?void 0:n[t];return i===void 0?!1:(r=this.index)===null||r===void 0?void 0:r.hasRefSeq(i)}async lineCount(t){var n;const r=(n=this.chrToIndex)===null||n===void 0?void 0:n[t];return r===void 0||!this.index?0:this.index.lineCount(r)}async indexCov(t,n,r){var i;if(!this.index)return[];await this.index.parse();const a=(i=this.chrToIndex)===null||i===void 0?void 0:i[t];return a===void 0?[]:this.index.indexCov(a,n,r)}async blocksForRange(t,n,r,i){var a;if(!this.index)return[];await this.index.parse();const o=(a=this.chrToIndex)===null||a===void 0?void 0:a[t];return o===void 0?[]:this.index.blocksForRange(o,n,r,i)}}async function Ck(e,t){const n=await Promise.all(e.map(async r=>{const{url:i,headers:a}=r;if(i.startsWith("data:"))return we.Buffer.from(i.split(",")[1],"base64");{const{referer:o,...s}=a,c=await fetch(i,{...t,headers:{...t==null?void 0:t.headers,...s}});if(!c.ok)throw new Error(`HTTP ${c.status} fetching ${i}: ${await c.text()}`);return we.Buffer.from(await c.arrayBuffer())}}));return we.Buffer.concat(await Promise.all(n.map(r=>ea(r))))}class tJ extends _k{constructor(t){super({htsget:!0}),this.baseUrl=t.baseUrl,this.trackId=t.trackId}async*streamRecordsForRange(t,n,r,i){var a;const s=`${`${this.baseUrl}/${this.trackId}`}?referenceName=${t}&start=${n}&end=${r}&format=BAM`,c=(a=this.chrToIndex)===null||a===void 0?void 0:a[t];if(c===void 0)yield[];else{const l=await fetch(s,{...i});if(!l.ok)throw new Error(`HTTP ${l.status} fetching ${s}: ${await l.text()}`);const u=await l.json(),f=await Ck(u.htsget.urls.slice(1),i);yield*this._fetchChunkFeatures([{buffer:f,_fetchedSize:void 0,bin:0,compareTo(){return 0},toUniqueString(){return`${t}_${n}_${r}`},fetchedSize(){return 0},minv:{dataPosition:0,blockPosition:0,compareTo:()=>0},maxv:{dataPosition:Number.MAX_SAFE_INTEGER,blockPosition:0,compareTo:()=>0},toString(){return`${t}_${n}_${r}`}}],c,n,r,i)}}async _readChunk({chunk:t}){if(!t.buffer)throw new Error("expected chunk.buffer in htsget");return{data:t.buffer,cpositions:[],dpositions:[],chunk:t}}async getHeader(t={}){const n=`${this.baseUrl}/${this.trackId}?referenceName=na&class=header`,r=await fetch(n,t);if(!r.ok)throw new Error(`HTTP ${r.status} fetching ${n}: ${await r.text()}`);const i=await r.json(),a=await Ck(i.htsget.urls,t);if(a.readInt32LE(0)!==Ek)throw new Error("Not a BAM file");const o=a.readInt32LE(4),s=a.toString("utf8",8,8+o),c=Ak(s),l=[],u={},f=c.filter(h=>h.tag==="SQ");for(const[h,d]of f.entries()){let p="",g=0;for(const b of d.data)b.tag==="SN"?p=b.value:b.tag==="LN"&&(g=+b.value);u[p]=h,l[h]={refName:p,length:g}}return this.chrToIndex=u,this.indexToChr=l,c}}const nJ=Object.freeze(Object.defineProperty({__proto__:null,BAI:nc,BamFile:_k,BamRecord:xk,CSI:U0,HtsgetFile:tJ},Symbol.toStringTag,{value:"Module"}));function kk(e){if(e.greaterThan(Number.MAX_SAFE_INTEGER)||e.lessThan(Number.MIN_SAFE_INTEGER))throw new Error("integer overflow");return e.toNumber()}class rJ extends Error{}function rc(e){if(e&&e.aborted){if(typeof DOMException<"u")throw new DOMException("aborted","AbortError");{const t=new rJ("aborted");throw t.code="ERR_ABORTED",t}}}function iJ(e,t){return t.minv.blockPosition-e.maxv.blockPosition<65e3&&t.maxv.blockPosition-e.minv.blockPosition<5e6}function Tk(e,t){const n=[];let r=null;return e.length===0?e:(e.sort(function(i,a){const o=i.minv.blockPosition-a.minv.blockPosition;return o!==0?o:i.minv.dataPosition-a.minv.dataPosition}),e.forEach(i=>{(!t||i.maxv.compareTo(t)>0)&&(r===null?(n.push(i),r=i):iJ(r,i)?i.maxv.compareTo(r.maxv)>0&&(r.maxv=i.maxv):(n.push(i),r=i))}),n)}class p2{constructor(t,n){this.blockPosition=t,this.dataPosition=n}toString(){return`${this.blockPosition}:${this.dataPosition}`}compareTo(t){return this.blockPosition-t.blockPosition||this.dataPosition-t.dataPosition}static min(...t){let n,r=0;for(;!n;r+=1)n=t[r];for(;r<t.length;r+=1)n.compareTo(t[r])>0&&(n=t[r]);return n}}function ic(e,t=0,n=!1){if(n)throw new Error("big-endian virtual file offsets not implemented");return new p2(e[t+7]*1099511627776+e[t+6]*4294967296+e[t+5]*16777216+e[t+4]*65536+e[t+3]*256+e[t+2],e[t+1]<<8|e[t])}class $0{constructor(t,n,r,i=void 0){this.minv=t,this.maxv=n,this.bin=r,this._fetchedSize=i}toUniqueString(){return`${this.minv}..${this.maxv} (bin ${this.bin}, fetchedSize ${this.fetchedSize()})`}toString(){return this.toUniqueString()}compareTo(t){return this.minv.compareTo(t.minv)||this.maxv.compareTo(t.maxv)||this.bin-t.bin}fetchedSize(){return this._fetchedSize!==void 0?this._fetchedSize:this.maxv.blockPosition+65536-this.minv.blockPosition}}class Ik{constructor({filehandle:t,renameRefSeqs:n=r=>r}){this.filehandle=t,this.renameRefSeq=n}async getMetadata(t={}){const{indices:n,...r}=await this.parse(t);return r}_findFirstData(t,n){return t?t.compareTo(n)>0?n:t:n}async parse(t={}){return this.parseP||(this.parseP=this._parse(t).catch(n=>{throw this.parseP=void 0,n})),this.parseP}async hasRefSeq(t,n={}){var r;return!!(!((r=(await this.parse(n)).indices[t])===null||r===void 0)&&r.binIndex)}}const aJ=21578324,Rk=14;function oJ(e,t){return e+=1,t-=1,[[0,0],[1+(e>>26),1+(t>>26)],[9+(e>>23),9+(t>>23)],[73+(e>>20),73+(t>>20)],[585+(e>>17),585+(t>>17)],[4681+(e>>14),4681+(t>>14)]]}class H0 extends Ik{async lineCount(t,n={}){const r=await this.parse(n);if(!r)return-1;const i=r.refNameToId[t];if(!r.indices[i])return-1;const{stats:o}=r.indices[i];return o?o.lineCount:-1}async _parse(t={}){const n=await this.filehandle.readFile(t),r=await ea(n);if(rc(t.signal),r.readUInt32LE(0)!==aJ)throw new Error("Not a TBI file");const i=r.readInt32LE(4),a=r.readInt32LE(8),o=a&65536?"zero-based-half-open":"1-based-closed",c={0:"generic",1:"SAM",2:"VCF"}[a&15];if(!c)throw new Error(`invalid Tabix preset format flags ${a}`);const l={ref:r.readInt32LE(12),start:r.readInt32LE(16),end:r.readInt32LE(20)},u=r.readInt32LE(24),f=5,h=((1<<(f+1)*3)-1)/7,d=2**(14+f*3),p=u?String.fromCharCode(u):null,g=r.readInt32LE(28),b=r.readInt32LE(32),{refNameToId:y,refIdToName:w}=this._parseNameBytes(r.slice(36,36+b));let A=36+b,x;return{indices:new Array(i).fill(0).map(()=>{const _=r.readInt32LE(A);A+=4;const I={};let D;for(let O=0;O<_;O+=1){const ae=r.readUInt32LE(A);if(A+=4,ae>h+1)throw new Error("tabix index contains too many bins, please use a CSI index");if(ae===h+1){const se=r.readInt32LE(A);A+=4,se===2&&(D=this.parsePseudoBin(r,A)),A+=16*se}else{const se=r.readInt32LE(A);A+=4;const ve=new Array(se);for(let Pe=0;Pe<se;Pe+=1){const st=ic(r,A),Ne=ic(r,A+8);A+=16,x=this._findFirstData(x,st),ve[Pe]=new $0(st,Ne,ae)}I[ae]=ve}}const M=r.readInt32LE(A);A+=4;const G=new Array(M);for(let O=0;O<M;O+=1)G[O]=ic(r,A),A+=8,x=this._findFirstData(x,G[O]);return{binIndex:I,linearIndex:G,stats:D}}),metaChar:p,maxBinNumber:h,maxRefLength:d,skipLines:g,firstDataLine:x,columnNumbers:l,coordinateType:o,format:c,refIdToName:w,refNameToId:y,maxBlockSize:65536}}parsePseudoBin(t,n){return{lineCount:kk(p0.fromBytesLE(t.slice(n+16,n+24),!0))}}_parseNameBytes(t){let n=0,r=0;const i=[],a={};for(let o=0;o<t.length;o+=1)if(!t[o]){if(r<o){let s=t.toString("utf8",r,o);s=this.renameRefSeq(s),i[n]=s,a[s]=n}r=o+1,n+=1}return{refNameToId:a,refIdToName:i}}async blocksForRange(t,n,r,i={}){n<0&&(n=0);const a=await this.parse(i);if(!a)return[];const o=a.refNameToId[t],s=a.indices[o];if(!s)return[];(s.linearIndex.length?s.linearIndex[n>>Rk>=s.linearIndex.length?s.linearIndex.length-1:n>>Rk]:new p2(0,0))||console.warn("querying outside of possible tabix range");const l=oJ(n,r),u=[];for(const[g,b]of l)for(let y=g;y<=b;y++)if(s.binIndex[y])for(const w of s.binIndex[y])u.push(new $0(w.minv,w.maxv,y));const f=s.linearIndex.length;let h=null;const d=Math.min(n>>14,f-1),p=Math.min(r>>14,f-1);for(let g=d;g<=p;++g){const b=s.linearIndex[g];b&&(!h||b.compareTo(h)<0)&&(h=b)}return Tk(u,h)}}const sJ=21582659,cJ=38359875;function lJ(e,t){return e*2**t}function Dk(e,t){return Math.floor(e/2**t)}class g2 extends Ik{constructor(t){super(t),this.maxBinNumber=0,this.depth=0,this.minShift=0}async lineCount(t,n={}){const r=await this.parse(n);if(!r)return-1;const i=r.refNameToId[t];if(!r.indices[i])return-1;const{stats:o}=r.indices[i];return o?o.lineCount:-1}indexCov(){throw new Error("CSI indexes do not support indexcov")}parseAuxData(t,n){const r=t.readInt32LE(n),i=r&65536?"zero-based-half-open":"1-based-closed",a={0:"generic",1:"SAM",2:"VCF"}[r&15];if(!a)throw new Error(`invalid Tabix preset format flags ${r}`);const o={ref:t.readInt32LE(n+4),start:t.readInt32LE(n+8),end:t.readInt32LE(n+12)},s=t.readInt32LE(n+16),c=s?String.fromCharCode(s):null,l=t.readInt32LE(n+20),u=t.readInt32LE(n+24),{refIdToName:f,refNameToId:h}=this._parseNameBytes(t.slice(n+28,n+28+u));return{refIdToName:f,refNameToId:h,skipLines:l,metaChar:c,columnNumbers:o,format:a,coordinateType:i}}_parseNameBytes(t){let n=0,r=0;const i=[],a={};for(let o=0;o<t.length;o+=1)if(!t[o]){if(r<o){let s=t.toString("utf8",r,o);s=this.renameRefSeq(s),i[n]=s,a[s]=n}r=o+1,n+=1}return{refNameToId:a,refIdToName:i}}async _parse(t={}){const n=await ea(await this.filehandle.readFile(t));let r;if(n.readUInt32LE(0)===sJ)r=1;else if(n.readUInt32LE(0)===cJ)r=2;else throw new Error("Not a CSI file");this.minShift=n.readInt32LE(4),this.depth=n.readInt32LE(8),this.maxBinNumber=((1<<(this.depth+1)*3)-1)/7;const i=2**(this.minShift+this.depth*3),a=n.readInt32LE(12),o=a&&a>=30?this.parseAuxData(n,16):{refIdToName:[],refNameToId:{},metaChar:null,columnNumbers:{ref:0,start:1,end:2},coordinateType:"zero-based-half-open",format:"generic"},s=n.readInt32LE(16+a);let c,l=16+a+4;const u=new Array(s).fill(0).map(()=>{const f=n.readInt32LE(l);l+=4;const h={};let d;for(let p=0;p<f;p+=1){const g=n.readUInt32LE(l);if(g>this.maxBinNumber)d=this.parsePseudoBin(n,l+4),l+=4+8+4+16+16;else{const b=ic(n,l+4);c=this._findFirstData(c,b);const y=n.readInt32LE(l+12);l+=16;const w=new Array(y);for(let A=0;A<y;A+=1){const x=ic(n,l),C=ic(n,l+8);l+=16,w[A]=new $0(x,C,g)}h[g]=w}}return{binIndex:h,stats:d}});return{...o,csi:!0,refCount:s,maxBlockSize:65536,firstDataLine:c,csiVersion:r,indices:u,depth:this.depth,maxBinNumber:this.maxBinNumber,maxRefLength:i}}parsePseudoBin(t,n){return{lineCount:kk(p0.fromBytesLE(t.slice(n+28,n+36),!0))}}async blocksForRange(t,n,r,i={}){n<0&&(n=0);const a=await this.parse(i);if(!a)return[];const o=a.refNameToId[t],s=a.indices[o];if(!s)return[];const c=this.reg2bins(n,r),l=[];for(const[u,f]of c)for(let h=u;h<=f;h++)if(s.binIndex[h])for(const d of s.binIndex[h])l.push(new $0(d.minv,d.maxv,h));return Tk(l,new p2(0,0))}reg2bins(t,n){t-=1,t<1&&(t=1),n>2**50&&(n=2**34),n-=1;let r=0,i=0,a=this.minShift+this.depth*3;const o=[];for(;r<=this.depth;a-=3,i+=lJ(1,r*3),r+=1){const s=i+Dk(t,a),c=i+Dk(n,a);if(c-s+o.length>this.maxBinNumber)throw new Error(`query ${t}-${n} is too large for current binning scheme (shift ${this.minShift}, depth ${this.depth}), try a smaller query or a coarser index binning scheme`);o.push([s,c])}return o}}const m2=typeof TextDecoder<"u"?new TextDecoder("utf8"):void 0;function uJ(e){return new Promise(t=>setTimeout(t,e))}class fJ{constructor({path:t,filehandle:n,tbiPath:r,tbiFilehandle:i,csiPath:a,csiFilehandle:o,yieldTime:s=500,chunkSizeLimit:c=5e7,renameRefSeqs:l=f=>f,chunkCacheSize:u=5*2**20}){if(n)this.filehandle=n;else if(t)this.filehandle=new kt(t);else throw new TypeError("must provide either filehandle or path");if(i)this.index=new H0({filehandle:i,renameRefSeqs:l});else if(o)this.index=new g2({filehandle:o,renameRefSeqs:l});else if(r)this.index=new H0({filehandle:new kt(r),renameRefSeqs:l});else if(a)this.index=new g2({filehandle:new kt(a),renameRefSeqs:l});else if(t)this.index=new H0({filehandle:new kt(`${t}.tbi`),renameRefSeqs:l});else throw new TypeError("must provide one of tbiFilehandle, tbiPath, csiFilehandle, or csiPath");this.chunkSizeLimit=c,this.renameRefSeq=l,this.yieldTime=s,this.chunkCache=new A0({cache:new E0({maxSize:Math.floor(u/65536)}),fill:(f,h)=>this.readChunk(f,{signal:h})})}async getLines(t,n,r,i){var a;let o,s={},c;if(i===void 0)throw new TypeError("line callback must be provided");if(typeof i=="function"?c=i:(s=i,c=i.lineCallback,o=i.signal),t===void 0)throw new TypeError("must provide a reference sequence name");if(!c)throw new TypeError("line callback must be provided");const l=await this.index.getMetadata(s);rc(o);const u=n??0,f=r??l.maxRefLength;if(!(u<=f))throw new TypeError("invalid start and end coordinates. start must be less than or equal to end");if(u===f)return;const h=await this.index.blocksForRange(t,u,f,s);rc(o);for(const p of h){const g=p.fetchedSize();if(g>this.chunkSizeLimit)throw new Error(`Too much data. Chunk size ${g.toLocaleString()} bytes exceeds chunkSizeLimit of ${this.chunkSizeLimit.toLocaleString()}.`)}let d=Date.now();for(const p of h){let g;const{buffer:b,cpositions:y,dpositions:w}=await this.chunkCache.get(p.toString(),p,o);rc(o);let A=0,x=0;for(;A<b.length;){const C=b.indexOf(`
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3440
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`,A);if(C===-1)break;const _=b.slice(A,C),I=(a=m2==null?void 0:m2.decode(_))!==null&&a!==void 0?a:_.toString();if(w){for(;A+p.minv.dataPosition>=w[x++];);x--}const{startCoordinate:D,overlaps:M}=this.checkLine(l,t,u,f,I);if(g!==void 0&&D!==void 0&&g>D)throw new Error(`Lines not sorted by start coordinate (${g} > ${D}), this file is not usable with Tabix.`);if(g=D,M)c(I.trim(),y[x]*256+(A-w[x])+p.minv.dataPosition+1);else if(D!==void 0&&D>=f)return;this.yieldTime&&d-Date.now()>this.yieldTime&&(d=Date.now(),rc(o),await uJ(1)),A=C+1}}}async getMetadata(t={}){return this.index.getMetadata(t)}async getHeaderBuffer(t={}){const{firstDataLine:n,metaChar:r,maxBlockSize:i}=await this.getMetadata(t);rc(t.signal);const a=((n==null?void 0:n.blockPosition)||0)+i,o=await this._readRegion(0,a,t),s=await ea(o);if(r){let c=-1;const l=`
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3441
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`.charCodeAt(0),u=r.charCodeAt(0);for(let f=0;f<s.length&&!(f===c+1&&s[f]!==u);f+=1)s[f]===l&&(c=f);return s.slice(0,c+1)}return s}async getHeader(t={}){return(await this.getHeaderBuffer(t)).toString("utf8")}async getReferenceSequenceNames(t={}){return(await this.getMetadata(t)).refIdToName}checkLine(t,n,r,i,a){const{columnNumbers:o,metaChar:s,coordinateType:c,format:l}=t;if(s&&a.startsWith(s))return{overlaps:!1};let{ref:u,start:f,end:h}=o;u||(u=0),f||(f=0),h||(h=0),l==="VCF"&&(h=8);const d=Math.max(u,f,h);let p=1,g=0,b="",y=-1/0;for(let w=0;w<a.length+1;w+=1)if(a[w]===" "||w===a.length){if(p===u){if(this.renameRefSeq(a.slice(g,w))!==n)return{overlaps:!1}}else if(p===f){if(y=parseInt(a.slice(g,w),10),c==="1-based-closed"&&(y-=1),y>=i)return{startCoordinate:y,overlaps:!1};if((h===0||h===f)&&y+1<=r)return{startCoordinate:y,overlaps:!1}}else if(l==="VCF"&&p===4)b=a.slice(g,w);else if(p===h&&(l==="VCF"?this._getVcfEnd(y,b,a.slice(g,w)):parseInt(a.slice(g,w),10))<=r)return{overlaps:!1};if(g=w+1,p+=1,p>d)break}return{startCoordinate:y,overlaps:!0}}_getVcfEnd(t,n,r){let i=t+n.length;const a=r.includes("SVTYPE=TRA");if(r[0]!=="."&&!a){let o=";";for(let s=0;s<r.length;s+=1){if(o===";"&&r.slice(s,s+4)==="END="){let c=r.indexOf(";",s);c===-1&&(c=r.length),i=parseInt(r.slice(s+4,c),10);break}o=r[s]}}else if(a)return t+1;return i}async lineCount(t,n={}){return this.index.lineCount(t,n)}async _readRegion(t,n,r={}){const i=we.Buffer.alloc(n),{bytesRead:a,buffer:o}=await this.filehandle.read(i,0,n,t,r);return o.slice(0,a)}async readChunk(t,n={}){const r=await this._readRegion(t.minv.blockPosition,t.fetchedSize(),n);return jC(r,t)}}const hJ=Object.freeze(Object.defineProperty({__proto__:null,CSI:g2,TBI:H0,TabixIndexedFile:fJ},Symbol.toStringTag,{value:"Module"}));var b2={exports:{}},ac=typeof Reflect=="object"?Reflect:null,Bk=ac&&typeof ac.apply=="function"?ac.apply:function(t,n,r){return Function.prototype.apply.call(t,n,r)},G0;ac&&typeof ac.ownKeys=="function"?G0=ac.ownKeys:Object.getOwnPropertySymbols?G0=function(t){return Object.getOwnPropertyNames(t).concat(Object.getOwnPropertySymbols(t))}:G0=function(t){return Object.getOwnPropertyNames(t)};function dJ(e){console&&console.warn&&console.warn(e)}var Fk=Number.isNaN||function(t){return t!==t};function Le(){Le.init.call(this)}b2.exports=Le,b2.exports.once=bJ,Le.EventEmitter=Le,Le.prototype._events=void 0,Le.prototype._eventsCount=0,Le.prototype._maxListeners=void 0;var Pk=10;function V0(e){if(typeof e!="function")throw new TypeError('The "listener" argument must be of type Function. 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S=T._readableState;c("emitReadable_",S.destroyed,S.length,S.ended),!S.destroyed&&(S.length||S.ended)&&(T.emit("readable"),S.emittedReadable=!1),S.needReadable=!S.flowing&&!S.ended&&S.length<=S.highWaterMark,N(T)}function tt(T,S){S.readingMore||(S.readingMore=!0,process.nextTick(ut,T,S))}function ut(T,S){for(;!S.reading&&!S.ended&&(S.length<S.highWaterMark||S.flowing&&S.length===0);){var V=S.length;if(c("maybeReadMore read 0"),T.read(0),V===S.length)break}S.readingMore=!1}M.prototype._read=function(T){C(this,new b("_read()"))},M.prototype.pipe=function(T,S){var V=this,Y=this._readableState;switch(Y.pipesCount){case 0:Y.pipes=T;break;case 1:Y.pipes=[Y.pipes,T];break;default:Y.pipes.push(T);break}Y.pipesCount+=1,c("pipe count=%d opts=%j",Y.pipesCount,S);var de=(!S||S.end!==!1)&&T!==process.stdout&&T!==process.stderr,ie=de?un:Br;Y.endEmitted?process.nextTick(ie):V.once("end",ie),T.on("unpipe",pe);function pe(E,m){c("onunpipe"),E===V&&m&&m.hasUnpiped===!1&&(m.hasUnpiped=!0,da())}function un(){c("onend"),T.end()}var fa=Te(V);T.on("drain",fa);var ha=!1;function da(){c("cleanup"),T.removeListener("close",pa),T.removeListener("finish",fn),T.removeListener("drain",fa),T.removeListener("error",fi),T.removeListener("unpipe",pe),V.removeListener("end",un),V.removeListener("end",Br),V.removeListener("data",Gt),ha=!0,Y.awaitDrain&&(!T._writableState||T._writableState.needDrain)&&fa()}V.on("data",Gt);function Gt(E){c("ondata");var m=T.write(E);c("dest.write",m),m===!1&&((Y.pipesCount===1&&Y.pipes===T||Y.pipesCount>1&&Q(Y.pipes,T)!==-1)&&!ha&&(c("false write response, pause",Y.awaitDrain),Y.awaitDrain++),V.pause())}function fi(E){c("onerror",E),Br(),T.removeListener("error",fi),t(T,"error")===0&&C(T,E)}I(T,"error",fi);function pa(){T.removeListener("finish",fn),Br()}T.once("close",pa);function fn(){c("onfinish"),T.removeListener("close",pa),Br()}T.once("finish",fn);function Br(){c("unpipe"),V.unpipe(T)}return T.emit("pipe",V),Y.flowing||(c("pipe resume"),V.resume()),T};function 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T==="data"?(Y.readableListening=this.listenerCount("readable")>0,Y.flowing!==!1&&this.resume()):T==="readable"&&!Y.endEmitted&&!Y.readableListening&&(Y.readableListening=Y.needReadable=!0,Y.flowing=!1,Y.emittedReadable=!1,c("on readable",Y.length,Y.reading),Y.length?Ne(this):Y.reading||process.nextTick(Rt,this)),V},M.prototype.addListener=M.prototype.on,M.prototype.removeListener=function(T,S){var V=n.prototype.removeListener.call(this,T,S);return T==="readable"&&process.nextTick(Ie,this),V},M.prototype.removeAllListeners=function(T){var S=n.prototype.removeAllListeners.apply(this,arguments);return(T==="readable"||T===void 0)&&process.nextTick(Ie,this),S};function Ie(T){var S=T._readableState;S.readableListening=T.listenerCount("readable")>0,S.resumeScheduled&&!S.paused?S.flowing=!0:T.listenerCount("data")>0&&T.resume()}function Rt(T){c("readable nexttick read 0"),T.read(0)}M.prototype.resume=function(){var T=this._readableState;return T.flowing||(c("resume"),T.flowing=!T.readableListening,ln(this,T)),T.paused=!1,this};function ln(T,S){S.resumeScheduled||(S.resumeScheduled=!0,process.nextTick(Ve,T,S))}function Ve(T,S){c("resume",S.reading),S.reading||T.read(0),S.resumeScheduled=!1,T.emit("resume"),N(T),S.flowing&&!S.reading&&T.read(0)}M.prototype.pause=function(){return c("call pause flowing=%j",this._readableState.flowing),this._readableState.flowing!==!1&&(c("pause"),this._readableState.flowing=!1,this.emit("pause")),this._readableState.paused=!0,this};function N(T){var S=T._readableState;for(c("flow",S.flowing);S.flowing&&T.read()!==null;);}M.prototype.wrap=function(T){var S=this,V=this._readableState,Y=!1;T.on("end",function(){if(c("wrapped end"),V.decoder&&!V.ended){var pe=V.decoder.end();pe&&pe.length&&S.push(pe)}S.push(null)}),T.on("data",function(pe){if(c("wrapped data"),V.decoder&&(pe=V.decoder.write(pe)),!(V.objectMode&&pe==null)&&!(!V.objectMode&&(!pe||!pe.length))){var 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this._flush=="function"&&!this._readableState.destroyed?this._flush(function(f,h){l(u,f,h)}):l(this,null,null)}s.prototype.push=function(u,f){return this._transformState.needTransform=!1,a.prototype.push.call(this,u,f)},s.prototype._transform=function(u,f,h){h(new t("_transform()"))},s.prototype._write=function(u,f,h){var d=this._transformState;if(d.writecb=h,d.writechunk=u,d.writeencoding=f,!d.transforming){var p=this._readableState;(d.needTransform||p.needReadable||p.length<p.highWaterMark)&&this._read(p.highWaterMark)}},s.prototype._read=function(u){var f=this._transformState;f.writechunk!==null&&!f.transforming?(f.transforming=!0,this._transform(f.writechunk,f.writeencoding,f.afterTransform)):f.needTransform=!0},s.prototype._destroy=function(u,f){a.prototype._destroy.call(this,u,function(h){f(h)})};function l(u,f,h){if(f)return u.emit("error",f);if(h!=null&&u.push(h),u._writableState.length)throw new i;if(u._transformState.transforming)throw new r;return u.push(null)}return L2}var N2,lT;function NJ(){if(lT)return N2;lT=1,N2=t;var e=cT();oc(t,e);function t(n){if(!(this instanceof t))return new t(n);e.call(this,n)}return t.prototype._transform=function(n,r,i){i(null,n)},N2}var z2,uT;function zJ(){if(uT)return z2;uT=1;var e;function t(h){var d=!1;return function(){d||(d=!0,h.apply(void 0,arguments))}}var n=sc().codes,r=n.ERR_MISSING_ARGS,i=n.ERR_STREAM_DESTROYED;function a(h){if(h)throw h}function o(h){return h.setHeader&&typeof h.abort=="function"}function s(h,d,p,g){g=t(g);var b=!1;h.on("close",function(){b=!0}),e===void 0&&(e=F2()),e(h,{readable:d,writable:p},function(w){if(w)return g(w);b=!0,g()});var y=!1;return function(w){if(!b&&!y){if(y=!0,o(h))return h.abort();if(typeof h.destroy=="function")return h.destroy();g(w||new i("pipe"))}}}function c(h){h()}function l(h,d){return h.pipe(d)}function u(h){return!h.length||typeof h[h.length-1]!="function"?a:h.pop()}function f(){for(var h=arguments.length,d=new Array(h),p=0;p<h;p++)d[p]=arguments[p];var g=u(d);if(Array.isArray(d[0])&&(d=d[0]),d.length<2)throw new r("streams");var b,y=d.map(function(w,A){var x=A<d.length-1,C=A>0;return s(w,x,C,function(_){b||(b=_),_&&y.forEach(c),!x&&(y.forEach(c),g(b))})});return d.reduce(l)}return z2=f,z2}var fT=On,U2=y2.EventEmitter,UJ=oc;UJ(On,U2),On.Readable=oT(),On.Writable=Jk(),On.Duplex=cc(),On.Transform=cT(),On.PassThrough=NJ(),On.finished=F2(),On.pipeline=zJ(),On.Stream=On;function On(){U2.call(this)}On.prototype.pipe=function(e,t){var n=this;function r(u){e.writable&&e.write(u)===!1&&n.pause&&n.pause()}n.on("data",r);function i(){n.readable&&n.resume&&n.resume()}e.on("drain",i),!e._isStdio&&(!t||t.end!==!1)&&(n.on("end",o),n.on("close",s));var a=!1;function o(){a||(a=!0,e.end())}function s(){a||(a=!0,typeof e.destroy=="function"&&e.destroy())}function c(u){if(l(),U2.listenerCount(this,"error")===0)throw u}n.on("error",c),e.on("error",c);function l(){n.removeListener("data",r),e.removeListener("drain",i),n.removeListener("end",o),n.removeListener("close",s),n.removeListener("error",c),e.removeListener("error",c),n.removeListener("end",l),n.removeListener("close",l),e.removeListener("close",l)}return n.on("end",l),n.on("close",l),e.on("close",l),e.emit("pipe",n),e};function Ju(e){return e.replace(/%([0-9A-Fa-f]{2})/g,(t,n)=>String.fromCharCode(parseInt(n,16)))}function hT(e,t){return String(t).replace(e,n=>`%${n.charCodeAt(0).toString(16).toUpperCase().padStart(2,"0")}`)}function ef(e){return hT(/[\n;\r\t=%&,\x00-\x1f\x7f-\xff]/g,e)}function ii(e){return hT(/[\n\r\t%\x00-\x1f\x7f-\xff]/g,e)}function dT(e){if(!(e&&e.length)||e===".")return{};const t={};return e.replace(/\r?\n$/,"").split(";").forEach(n=>{const r=n.split("=",2);if(!(r[1]&&r[1].length))return;r[0]=r[0].trim();let i=t[r[0].trim()];i||(i=[],t[r[0]]=i),i.push(...r[1].split(",").map(a=>a.trim()).map(Ju))}),t}function pT(e){const t=e.split(" ").map(r=>r==="."||r===""?null:r);return{seq_id:t[0]&&Ju(t[0]),source:t[1]&&Ju(t[1]),type:t[2]&&Ju(t[2]),start:t[3]===null?null:parseInt(t[3],10),end:t[4]===null?null:parseInt(t[4],10),score:t[5]===null?null:parseFloat(t[5]),strand:t[6],phase:t[7],attributes:t[8]===null?null:dT(t[8])}}function gT(e){const t=/^\s*##\s*(\S+)\s*(.*)/.exec(e);if(!t)return null;const[,n]=t;let[,,r]=t;const i={directive:n};if(r.length&&(r=r.replace(/\r?\n$/,""),i.value=r),n==="sequence-region"){const a=r.split(/\s+/,3);return{...i,seq_id:a[0],start:a[1]&&a[1].replace(/\D/g,""),end:a[2]&&a[2].replace(/\D/g,"")}}else if(n==="genome-build"){const[a,o]=r.split(/\s+/,2);return{...i,source:a,buildName:o}}return i}function mT(e){const t=[];return Object.entries(e).forEach(([n,r])=>{if(!r)return;let i;r.hasOwnProperty("toString")?i=ef(r.toString()):Array.isArray(r)?i=r.map(ef).join(","):i=ef(r),t.push(`${ef(n)}=${i}`)}),t.length?t.join(";"):"."}function $J(e,t){const n=e.attributes===null||e.attributes===void 0?".":mT(e.attributes),i=`${[e.seq_id===null?".":ii(e.seq_id),e.source===null?".":ii(e.source),e.type===null?".":ii(e.type),e.start===null?".":ii(e.start),e.end===null?".":ii(e.end),e.score===null?".":ii(e.score),e.strand===null?".":ii(e.strand),e.phase===null?".":ii(e.phase),n].join(" ")}
|
|
3442
|
+
`;return t[i]?"":(t[i]=!0,i)}function j0(e,t){if(Array.isArray(e))return e.map(r=>j0(r,t)).join("");const n=[$J(e,t)];return HJ(e)&&n.push(...e.child_features.map(r=>j0(r,t)),...e.derived_features.map(r=>j0(r,t))),n.join("")}function bT(e){return j0(e,{})}function yT(e){let t=`##${e.directive}`;return e.value&&(t+=` ${e.value}`),t+=`
|
|
3440
3443
|
`,t}function vT(e){return`# ${e.comment}
|
|
3441
3444
|
`}function $2(e){return`>${e.id}${e.description?` ${e.description}`:""}
|
|
3442
3445
|
${e.sequence}
|
|
3443
3446
|
`}function q0(e){function t(n){return"attributes"in n?bT(n):"directive"in n?yT(n):"sequence"in n?$2(n):"comment"in n?vT(n):`# (invalid item found during format)
|
|
3444
|
-
`}return Array.isArray(e)?e.map(t):t(e)}function
|
|
3447
|
+
`}return Array.isArray(e)?e.map(t):t(e)}function HJ(e){return e.child_features!==void 0&&e.derived_features!==void 0}const GJ=Object.freeze(Object.defineProperty({__proto__:null,escape:ef,escapeColumn:ii,formatAttributes:mT,formatComment:vT,formatDirective:yT,formatFeature:bT,formatItem:q0,formatSequence:$2,parseAttributes:dT,parseDirective:gT,parseFeature:pT,unescape:Ju},Symbol.toStringTag,{value:"Module"})),wT={Parent:"child_features",Derives_from:"derived_features"};class xT{constructor(t){this.seqCallback=t,this.currentSequence=void 0}addLine(t){const n=/^>\s*(\S+)\s*(.*)/.exec(t);n?(this._flush(),this.currentSequence={id:n[1],sequence:""},n[2]&&(this.currentSequence.description=n[2].trim())):this.currentSequence&&/\S/.test(t)&&(this.currentSequence.sequence+=t.replace(/\s/g,""))}_flush(){this.currentSequence&&this.seqCallback(this.currentSequence)}finish(){this._flush()}}class AT{constructor(t){this.fastaParser=void 0,this.eof=!1,this.lineNumber=0,this._underConstructionTopLevel=[],this._underConstructionById={},this._completedReferences={},this._underConstructionOrphans={};const n=()=>{};this.featureCallback=t.featureCallback||n,this.endCallback=t.endCallback||n,this.commentCallback=t.commentCallback||n,this.errorCallback=t.errorCallback||n,this.directiveCallback=t.directiveCallback||n,this.sequenceCallback=t.sequenceCallback||n,this.disableDerivesFromReferences=t.disableDerivesFromReferences||!1,this.bufferSize=t.bufferSize===void 0?1e3:t.bufferSize}addLine(t){if(this.fastaParser){this.fastaParser.addLine(t);return}if(this.eof)return;if(this.lineNumber+=1,/^\s*[^#\s>]/.test(t)){this._bufferLine(t);return}const n=/^\s*(#+)(.*)/.exec(t);if(n){const[,r]=n;let[,,i]=n;if(r.length===3)this._emitAllUnderConstructionFeatures();else if(r.length===2){const a=gT(t);a&&(a.directive==="FASTA"?(this._emitAllUnderConstructionFeatures(),this.eof=!0,this.fastaParser=new xT(this.sequenceCallback)):this._emitItem(a))}else i=i.replace(/\s*/,""),this._emitItem({comment:i})}else if(!/^\s*$/.test(t))if(/^\s*>/.test(t))this._emitAllUnderConstructionFeatures(),this.eof=!0,this.fastaParser=new xT(this.sequenceCallback),this.fastaParser.addLine(t);else{const r=t.replace(/\r?\n?$/g,"");throw new Error(`GFF3 parse error. Cannot parse '${r}'.`)}}finish(){this._emitAllUnderConstructionFeatures(),this.fastaParser&&this.fastaParser.finish(),this.endCallback()}_emitItem(t){Array.isArray(t)?this.featureCallback(t):"directive"in t?this.directiveCallback(t):"comment"in t&&this.commentCallback(t)}_enforceBufferSizeLimit(t=0){const n=r=>{r&&Array.isArray(r)&&r[0].attributes&&r[0].attributes.ID&&r[0].attributes.ID[0]&&(r[0].attributes.ID.forEach(a=>{delete this._underConstructionById[a],delete this._completedReferences[a]}),r.forEach(a=>{a.child_features&&a.child_features.forEach(o=>n(o)),a.derived_features&&a.derived_features.forEach(o=>n(o))}))};for(;this._underConstructionTopLevel.length+t>this.bufferSize;){const r=this._underConstructionTopLevel.shift();r&&(this._emitItem(r),n(r))}}_emitAllUnderConstructionFeatures(){if(this._underConstructionTopLevel.forEach(this._emitItem.bind(this)),this._underConstructionTopLevel=[],this._underConstructionById={},this._completedReferences={},Array.from(Object.values(this._underConstructionOrphans)).length)throw new Error(`some features reference other features that do not exist in the file (or in the same '###' scope). ${Object.keys(this._underConstructionOrphans)}`)}_bufferLine(t){var n,r,i;const o={...pT(t),child_features:[],derived_features:[]},s=((n=o.attributes)===null||n===void 0?void 0:n.ID)||[],c=((r=o.attributes)===null||r===void 0?void 0:r.Parent)||[],l=this.disableDerivesFromReferences?[]:((i=o.attributes)===null||i===void 0?void 0:i.Derives_from)||[];if(!s.length&&!c.length&&!l.length){this._emitItem([o]);return}let u;s.forEach(f=>{const h=this._underConstructionById[f];h?(h[h.length-1].type!==o.type&&this._parseError(`multi-line feature "${f}" has inconsistent types: "${o.type}", "${h[h.length-1].type}"`),h.push(o),u=h):(u=[o],this._enforceBufferSizeLimit(1),!c.length&&!l.length&&this._underConstructionTopLevel.push(u),this._underConstructionById[f]=u,this._resolveReferencesTo(u,f))}),this._resolveReferencesFrom(u||[o],{Parent:c,Derives_from:l},s)}_resolveReferencesTo(t,n){const r=this._underConstructionOrphans[n];r&&(t.forEach(i=>{i.child_features.push(...r.Parent)}),t.forEach(i=>{i.derived_features.push(...r.Derives_from)}),delete this._underConstructionOrphans[n])}_parseError(t){this.eof=!0,this.errorCallback(`${this.lineNumber}: ${t}`)}_resolveReferencesFrom(t,n,r){function i(a,o,s){let c=a[o];c||(c={},a[o]=c);const l=c[s]||!1;return c[s]=!0,l}n.Parent.forEach(a=>{const o=this._underConstructionById[a];if(o){const s=wT.Parent;r.filter(c=>i(this._completedReferences,c,`Parent,${a}`)).length||o.forEach(c=>{c[s].push(t)})}else{let s=this._underConstructionOrphans[a];s||(s={Parent:[],Derives_from:[]},this._underConstructionOrphans[a]=s),s.Parent.push(t)}}),n.Derives_from.forEach(a=>{const o=this._underConstructionById[a];if(o){const s=wT.Derives_from;r.filter(c=>i(this._completedReferences,c,`Derives_from,${a}`)).length||o.forEach(c=>{c[s].push(t)})}else{let s=this._underConstructionOrphans[a];s||(s={Parent:[],Derives_from:[]},this._underConstructionOrphans[a]=s),s.Derives_from.push(t)}})}}function H2(e){process&&process.nextTick?process.nextTick(e):e()}function ET(e){const t={encoding:"utf8",parseFeatures:!0,parseDirectives:!1,parseSequences:!0,parseComments:!1,bufferSize:1e3,disableDerivesFromReferences:!1,...e};return e.parseAll&&(t.parseFeatures=!0,t.parseDirectives=!0,t.parseComments=!0,t.parseSequences=!0),t}class VJ extends fT.Transform{constructor(t={}){super({objectMode:!0}),this.textBuffer="";const n=ET(t);this.encoding=t.encoding||"utf8",this.decoder=new SJ;const r=this.push.bind(this);this.parser=new AT({featureCallback:n.parseFeatures?r:void 0,directiveCallback:n.parseDirectives?r:void 0,commentCallback:n.parseComments?r:void 0,sequenceCallback:n.parseSequences?r:void 0,errorCallback:i=>this.emit("error",i),bufferSize:n.bufferSize,disableDerivesFromReferences:n.disableDerivesFromReferences})}_addLine(t){t&&this.parser.addLine(t)}_nextText(t){const n=(this.textBuffer+t).split(/\r?\n/);this.textBuffer=n.pop()||"",n.forEach(r=>this._addLine(r))}_transform(t,n,r){this._nextText(this.decoder.write(t)),H2(r)}_flush(t){this.decoder.end&&this._nextText(this.decoder.end()),this.textBuffer!=null&&this._addLine(this.textBuffer),this.parser.finish(),H2(t)}}function jJ(e={}){return new VJ(e)}function qJ(e,t={}){if(!e)return[];const n=ET(t),r=[],i=r.push.bind(r),a=new AT({featureCallback:n.parseFeatures?i:void 0,directiveCallback:n.parseDirectives?i:void 0,commentCallback:n.parseComments?i:void 0,sequenceCallback:n.parseSequences?i:void 0,disableDerivesFromReferences:n.disableDerivesFromReferences||!1,bufferSize:1/0,errorCallback:o=>{throw o}});return e.split(/\r?\n/).forEach(a.addLine.bind(a)),a.finish(),r}function WJ(e){const t=[],n=[];e.forEach(i=>{"sequence"in i?n.push(i):t.push(i)});let r=t.map(q0).join("");return n.length&&(r+=`##FASTA
|
|
3445
3448
|
`,r+=n.map($2).join("")),r}class ST extends fT.Transform{constructor(t={}){super(Object.assign(t,{objectMode:!0})),this.linesSinceLastSyncMark=0,this.haveWeEmittedData=!1,this.fastaMode=!1,this.minLinesBetweenSyncMarks=t.minSyncLines||100,this.insertVersionDirective=t.insertVersionDirective||!1}_transform(t,n,r){let i;if(!this.haveWeEmittedData&&this.insertVersionDirective){const a=Array.isArray(t)?t[0]:t;"directive"in a&&a.directive!=="gff-version"&&this.push(`##gff-version 3
|
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3446
3449
|
`)}if("sequence"in t&&!this.fastaMode&&(this.push(`##FASTA
|
|
3447
3450
|
`),this.fastaMode=!0),Array.isArray(t)?i=t.map(q0).join(""):i=q0(t),this.push(i),this.linesSinceLastSyncMark>=this.minLinesBetweenSyncMarks)this.push(`###
|
|
3448
3451
|
`),this.linesSinceLastSyncMark=0;else{let a=0;for(let o=0;o<i.length;o+=1)i[o]===`
|
|
3449
|
-
`&&(a+=1);this.linesSinceLastSyncMark+=a}this.haveWeEmittedData=!0,H2(r)}}function
|
|
3452
|
+
`&&(a+=1);this.linesSinceLastSyncMark+=a}this.haveWeEmittedData=!0,H2(r)}}function YJ(e={}){return new ST(e)}function ZJ(e,t,n={}){const r={insertVersionDirective:!0,...n};return new Promise((i,a)=>{e.pipe(new ST(r)).on("end",()=>i(null)).on("error",a).pipe(t)})}const QJ=Object.freeze(Object.defineProperty({__proto__:null,default:{parseStream:jJ,parseStringSync:qJ,formatSync:WJ,formatStream:YJ,formatFile:ZJ,util:GJ}},Symbol.toStringTag,{value:"Module"}));me.GenomeSpy=KE,me.GenomeSpyApp=u6,me.embed=Rq,me.html=$,me.icon=Z_,me.loadSpec=f6,Object.defineProperty(me,Symbol.toStringTag,{value:"Module"})});
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