npm - @erosolaraijs/cure - Versions diffs - 1.0.3 → 1.0.4 - Mend

@erosolaraijs/cure 1.0.3 → 1.0.4

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.

Files changed (9) hide show

package/dist/bin/cure.js CHANGED Viewed

@@ -6,7 +6,7 @@
 import * as readline from 'readline';
 import * as https from 'https';
 import { CancerTreatmentCapabilityModule } from '../capabilities/cancerTreatmentCapability.js';
-const VERSION = '1.0.3';
+const VERSION = '1.0.4';
 const XAI_MODEL = 'grok-4-1-fast-reasoning';
 // ANSI color codes
 const colors = {
@@ -23,6 +23,7 @@ const colors = {
 };
 let cancerTreatment;
 let conversationHistory = [];
+let xaiApiKey = process.env.XAI_API_KEY;
 const SYSTEM_PROMPT = `You are Cure, an advanced AI oncologist assistant powered by the Cure Cancer Treatment Framework. You help doctors, researchers, and patients with:
 1. Cancer diagnosis and staging analysis
@@ -51,10 +52,10 @@ Available commands the user can run:
 - /demo - Run framework demonstration
 - /help - Show available commands`;
 async function callXAI(userMessage) {
-    const apiKey = process.env.XAI_API_KEY;
-    if (!apiKey) {
-        return `${colors.yellow}Note: Set XAI_API_KEY environment variable for AI-powered responses.${colors.reset}\n\nI can help you with cancer treatment analysis. Try:\n  /analyze P001 - Analyze patient\n  /plan P001 - Design treatment plan\n  /discover EGFR Lung - Find drug targets\n  /demo - Run demonstration`;
+    if (!xaiApiKey) {
+        return `${colors.yellow}API key not set.${colors.reset} Use ${colors.cyan}/key YOUR_API_KEY${colors.reset} to set your xAI API key.\n\nGet your key at: https://console.x.ai`;
     }
+    const apiKey = xaiApiKey;
     conversationHistory.push({ role: 'user', content: userMessage });
     const messages = [
         { role: 'system', content: SYSTEM_PROMPT },
@@ -144,9 +145,9 @@ async function launchInteractiveMode() {
     const prompt = () => {
         process.stdout.write(`\n${colors.cyan}cure${colors.reset} ${colors.dim}>${colors.reset} `);
     };
-    const modelInfo = process.env.XAI_API_KEY
+    const modelInfo = xaiApiKey
         ? `${colors.green}Connected to xAI ${XAI_MODEL}${colors.reset}`
-        : `${colors.yellow}Set XAI_API_KEY for AI responses${colors.reset}`;
+        : `${colors.yellow}Use /key YOUR_API_KEY to enable AI${colors.reset}`;
     console.log(`${colors.dim}${modelInfo}${colors.reset}`);
     console.log(`${colors.dim}Type your question or /help for commands.${colors.reset}\n`);
     prompt();
@@ -205,7 +206,19 @@ async function processInput(input) {
                 return;
             case 'model':
                 console.log(`\n${colors.cyan}Model:${colors.reset} ${XAI_MODEL}`);
-                console.log(`${colors.cyan}API:${colors.reset} ${process.env.XAI_API_KEY ? 'Connected' : 'Not configured'}`);
+                console.log(`${colors.cyan}API:${colors.reset} ${xaiApiKey ? 'Connected' : 'Not configured'}`);
+                return;
+            case 'key':
+                if (args[0]) {
+                    xaiApiKey = args[0];
+                    console.log(`\n${colors.green}✓ API key set successfully${colors.reset}`);
+                    console.log(`${colors.dim}You can now chat with the AI oncologist.${colors.reset}`);
+                }
+                else {
+                    console.log(`\n${colors.cyan}API Status:${colors.reset} ${xaiApiKey ? 'Connected' : 'Not set'}`);
+                    console.log(`\n${colors.dim}Usage: /key YOUR_XAI_API_KEY${colors.reset}`);
+                    console.log(`${colors.dim}Get your key at: https://console.x.ai${colors.reset}`);
+                }
                 return;
             default:
                 console.log(`\n${colors.red}Unknown command: /${cmd}${colors.reset}`);
@@ -339,6 +352,7 @@ function printInteractiveHelp() {
     console.log(`
 ${colors.bold}Commands${colors.reset}
 ${colors.dim}─────────────────────────────${colors.reset}
+  ${colors.cyan}/key${colors.reset} [api_key]         Set xAI API key
   ${colors.cyan}/analyze${colors.reset} [patient]     Analyze patient data
   ${colors.cyan}/plan${colors.reset} [patient]        Design treatment plan
   ${colors.cyan}/discover${colors.reset} [gene]       Drug target discovery
@@ -356,6 +370,11 @@ ${colors.dim}──────────────────────
   "Explain pembrolizumab mechanism of action"
   "What biomarkers predict response to immunotherapy?"
   "Compare osimertinib vs erlotinib for EGFR mutations"
+${colors.bold}Setup${colors.reset}
+${colors.dim}─────────────────────────────${colors.reset}
+  1. Get API key at https://console.x.ai
+  2. Run: /key YOUR_API_KEY
 `);
 }
 function printHelp() {

package/dist/bin/cure.js.map CHANGED Viewed

	@@ -1 +1 @@
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package/dist/index.d.ts CHANGED Viewed

@@ -21,16 +21,18 @@
  * @packageDocumentation
  */
 export { CancerTreatmentCapabilityModule, type CancerTreatmentOperationType, type CancerPatient, type CancerTreatmentOperation, type CancerTreatmentResult, type TreatmentProtocol, type DrugTarget, type ImmunotherapyProtocol, type CombinationTherapy, type CancerCureResult } from './capabilities/cancerTreatmentCapability.js';
-export { RealWorldOncologyService, createRealWorldOncologyService, type RealWorldConfig, type RealWorldPatient, type ComprehensiveTreatmentPlan, type TreatmentOutcome } from './orchestrator/index.js';
-export { FHIRClient, EpicAdapter, CernerAdapter, FHIRPatientSummary, CancerDiagnosis, CancerBiomarkers, TreatmentHistory, type FHIRConfig, type FHIRResource, type FHIRPatient, type FHIRObservation, type FHIRCondition, type FHIRMedicationRequest, type FHIRProcedure, type FHIRDiagnosticReport } from './integrations/ehr/index.js';
-export { FoundationMedicineClient, GuardantHealthClient, TempusClient, UnifiedGenomicsService, type GenomicVariant, type CopyNumberAlteration, type GeneFusion, type GenomicReport, type TherapyMatch, type GenomicPlatformConfig } from './integrations/genomics/index.js';
-export { ClinicalTrialsGovClient, PatientTrialMatcher, type ClinicalTrial, type TrialLocation, type TrialEligibility, type PatientTrialMatch, type TrialSearchCriteria, type ClinicalTrialsConfig } from './integrations/clinicalTrials/index.js';
-export { HIPAAComplianceService, AuditLogger, ConsentManager, EncryptionService, AccessControlManager, DataMaskingService, type AuditLogEntry, type PatientConsent, type ConsentScope, type AccessPolicy, type AccessDecision, type HIPAAConfig } from './compliance/index.js';
-export { OutcomePredictionService, ResponsePredictor, SurvivalPredictor, ToxicityPredictor, ResistancePredictor, TherapyRanker, type PredictionInput, type ResponsePrediction, type SurvivalPrediction, type ToxicityPrediction, type ResistancePrediction, type TherapyRanking, type ModelMetadata, type MLConfig } from './ml/index.js';
-export { DrugSafetyService, DrugInteractionChecker, ContraindicationChecker, AllergyChecker, QTRiskAssessor, PharmacogenomicsChecker, BlackBoxWarningChecker, type DrugInteraction, type Contraindication, type AllergyAlert, type QTRiskAssessment, type PharmacogenomicAlert, type BlackBoxWarning, type SafetyCheckResult, type DrugSafetyConfig } from './safety/index.js';
-export { RetrospectiveValidator, CohortLoader, ConcordanceAnalyzer, PredictionAccuracyAnalyzer, SubgroupAnalyzer, ValidationReportGenerator, type ValidationCohort, type PatientOutcome, type ConcordanceResult, type PredictionAccuracy, type SubgroupAnalysis, type ValidationReport, type ValidationConfig } from './validation/index.js';
-export { ClinicalDecisionSupport, RecommendationEngine, OverrideManager, TumorBoardManager, RiskBenefitAnalyzer, ExplanationGenerator, type ClinicalRecommendation, type OverrideRecord, type TumorBoardCase, type RiskBenefitAnalysis, type RecommendationExplanation, type DecisionSupportConfig } from './clinician/index.js';
-export { PatientPortalService, PatientAccountManager, TreatmentSummaryService, SymptomTracker, MedicationAdherenceTracker, QualityOfLifeAssessment, SecureMessaging, EducationalContentService, AppointmentRequestService, PatientDashboard, type PatientAccount, type TreatmentSummary, type SymptomEntry, type AdherenceRecord, type QoLAssessment, type SecureMessage, type EducationalContent, type AppointmentRequest, type PatientDashboardData, type PatientPortalConfig } from './patient/index.js';
+import { RealWorldOncologyService as RWOService, createRealWorldOncologyService as createRWOService, type RealWorldConfig as RWConfig, type RealWorldPatient, type ComprehensiveTreatmentPlan, type TreatmentOutcome } from './orchestrator/realWorldOncology.js';
+export { RWOService as RealWorldOncologyService, createRWOService as createRealWorldOncologyService };
+export type { RWConfig as RealWorldConfig, RealWorldPatient, ComprehensiveTreatmentPlan, TreatmentOutcome };
+export { FHIRClient, EpicFHIRClient, CernerFHIRClient, createFHIRClient, type FHIRConfig, type FHIRPatient, type FHIRIdentifier, type FHIRHumanName, type FHIRAddress, type FHIRContactPoint, type FHIRCodeableConcept, type FHIRCoding, type FHIRExtension, type FHIRCondition, type FHIRObservation, type FHIRQuantity, type FHIRReference, type FHIRMedicationRequest, type FHIRDosage, type FHIRDiagnosticReport, type FHIRProcedure, type FHIRBundle, type FHIRResource, type CancerDiagnosis, type CancerBiomarkers, type TreatmentHistory, type AuditEvent } from './integrations/ehr/index.js';
+export { FoundationMedicineClient, GuardantHealthClient, TempusClient, UnifiedGenomicsService, createGenomicClient, type GenomicTestOrder, type GenomicTestResult, type GenomicVariant, type CopyNumberAlteration, type GeneFusion, type GenomicBiomarker, type MSIResult, type TMBResult, type HRDResult, type LOHResult, type TherapyMatch, type ClinicalTrialMatch, type GenomicPlatformConfig } from './integrations/genomics/index.js';
+export { ClinicalTrialsGovClient, type ClinicalTrial, type TrialStatus, type TrialPhase, type TrialIntervention, type TrialEligibility, type TrialLocation, type TrialSponsor, type TrialContact, type TrialArm, type TrialOutcome, type BiomarkerRequirement, type TrialSearchParams, type TrialSearchResult, type PatientProfile, type TrialMatch } from './integrations/clinicalTrials/index.js';
+export { HIPAAComplianceService, type AuditLogEntry, type AuditEventType, type AuditAction, type PatientConsent, type ConsentType, type DataCategory, type ConsentPurpose, type AccessPolicy, type AccessCondition, type AccessDecision, type EncryptionConfig, type EncryptedData, type DataMaskingConfig } from './compliance/index.js';
+export { OutcomePredictorService, type PatientFeatures, type TreatmentFeatures, type ResponsePrediction, type SurvivalPrediction, type ToxicityPrediction, type ResistancePrediction, type TherapyRanking, type MLModel, type ModelRegistry } from './ml/index.js';
+export { DrugSafetyService, type Drug, type CYP450Profile, type DrugInteraction, type Contraindication, type DosingGuideline, type AllergyCheck, type SafetyAlert, type PatientSafetyProfile } from './safety/index.js';
+export { RetrospectiveValidationService, type ValidationPatient, type SystemRecommendation, type ValidationResult, type CohortAnalysis } from './validation/index.js';
+export { ClinicalDecisionSupportService, type ClinicalRecommendation, type ClinicianOverride, type OverrideCategory, type TumorBoardCase, type AlertAcknowledgment } from './clinician/index.js';
+export { PatientPortalService, type PatientAccount, type PatientTreatmentSummary, type SymptomReport, type MedicationAdherenceLog, type QualityOfLifeAssessment, type PatientMessage, type EducationalContent, type AppointmentRequest } from './patient/index.js';
 /**
  * Quick start factory to create a fully configured oncology service
  *
@@ -54,12 +56,5 @@ export { PatientPortalService, PatientAccountManager, TreatmentSummaryService, S
  * const plan = await platform.generateComprehensivePlan(patient, 'DR001');
  * ```
  */
-export declare function createOncologyPlatform(config?: Partial<import('./orchestrator/index.js').RealWorldConfig>): Promise<RealWorldOncologyService>;
-declare const _default: {
-    createOncologyPlatform: typeof createOncologyPlatform;
-    createRealWorldOncologyService: any;
-    CancerTreatmentCapabilityModule: any;
-    RealWorldOncologyService: any;
-};
-export default _default;
+export declare function createOncologyPlatform(config?: Partial<RWConfig>): Promise<RWOService>;
 //# sourceMappingURL=index.d.ts.map

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package/dist/index.js CHANGED Viewed

@@ -27,40 +27,41 @@ export { CancerTreatmentCapabilityModule } from './capabilities/cancerTreatmentC
 // ═══════════════════════════════════════════════════════════════════════════════
 // REAL-WORLD ORCHESTRATION
 // ═══════════════════════════════════════════════════════════════════════════════
-export { RealWorldOncologyService, createRealWorldOncologyService } from './orchestrator/index.js';
+import { RealWorldOncologyService as RWOService, createRealWorldOncologyService as createRWOService } from './orchestrator/realWorldOncology.js';
+export { RWOService as RealWorldOncologyService, createRWOService as createRealWorldOncologyService };
 // ═══════════════════════════════════════════════════════════════════════════════
 // INTEGRATIONS
 // ═══════════════════════════════════════════════════════════════════════════════
 // EHR Integration (HL7 FHIR)
-export { FHIRClient, EpicAdapter, CernerAdapter, FHIRPatientSummary } from './integrations/ehr/index.js';
+export { FHIRClient, EpicFHIRClient, CernerFHIRClient, createFHIRClient } from './integrations/ehr/index.js';
 // Genomic Platforms
-export { FoundationMedicineClient, GuardantHealthClient, TempusClient, UnifiedGenomicsService } from './integrations/genomics/index.js';
+export { FoundationMedicineClient, GuardantHealthClient, TempusClient, UnifiedGenomicsService, createGenomicClient } from './integrations/genomics/index.js';
 // Clinical Trials
-export { ClinicalTrialsGovClient, PatientTrialMatcher } from './integrations/clinicalTrials/index.js';
+export { ClinicalTrialsGovClient } from './integrations/clinicalTrials/index.js';
 // ═══════════════════════════════════════════════════════════════════════════════
 // COMPLIANCE
 // ═══════════════════════════════════════════════════════════════════════════════
-export { HIPAAComplianceService, AuditLogger, ConsentManager, EncryptionService, AccessControlManager, DataMaskingService } from './compliance/index.js';
+export { HIPAAComplianceService } from './compliance/index.js';
 // ═══════════════════════════════════════════════════════════════════════════════
 // MACHINE LEARNING
 // ═══════════════════════════════════════════════════════════════════════════════
-export { OutcomePredictionService, ResponsePredictor, SurvivalPredictor, ToxicityPredictor, ResistancePredictor, TherapyRanker } from './ml/index.js';
+export { OutcomePredictorService } from './ml/index.js';
 // ═══════════════════════════════════════════════════════════════════════════════
 // SAFETY
 // ═══════════════════════════════════════════════════════════════════════════════
-export { DrugSafetyService, DrugInteractionChecker, ContraindicationChecker, AllergyChecker, QTRiskAssessor, PharmacogenomicsChecker, BlackBoxWarningChecker } from './safety/index.js';
+export { DrugSafetyService } from './safety/index.js';
 // ═══════════════════════════════════════════════════════════════════════════════
 // VALIDATION
 // ═══════════════════════════════════════════════════════════════════════════════
-export { RetrospectiveValidator, CohortLoader, ConcordanceAnalyzer, PredictionAccuracyAnalyzer, SubgroupAnalyzer, ValidationReportGenerator } from './validation/index.js';
+export { RetrospectiveValidationService } from './validation/index.js';
 // ═══════════════════════════════════════════════════════════════════════════════
 // CLINICIAN SUPPORT
 // ═══════════════════════════════════════════════════════════════════════════════
-export { ClinicalDecisionSupport, RecommendationEngine, OverrideManager, TumorBoardManager, RiskBenefitAnalyzer, ExplanationGenerator } from './clinician/index.js';
+export { ClinicalDecisionSupportService } from './clinician/index.js';
 // ═══════════════════════════════════════════════════════════════════════════════
 // PATIENT PORTAL
 // ═══════════════════════════════════════════════════════════════════════════════
-export { PatientPortalService, PatientAccountManager, TreatmentSummaryService, SymptomTracker, MedicationAdherenceTracker, QualityOfLifeAssessment, SecureMessaging, EducationalContentService, AppointmentRequestService, PatientDashboard } from './patient/index.js';
+export { PatientPortalService } from './patient/index.js';
 // ═══════════════════════════════════════════════════════════════════════════════
 // QUICK START FACTORY
 // ═══════════════════════════════════════════════════════════════════════════════
@@ -88,15 +89,8 @@ export { PatientPortalService, PatientAccountManager, TreatmentSummaryService, S
  * ```
  */
 export async function createOncologyPlatform(config) {
-    const service = createRealWorldOncologyService(config);
+    const service = createRWOService(config);
     await service.initialize();
     return service;
 }
-// Default export
-export default {
-    createOncologyPlatform,
-    createRealWorldOncologyService,
-    CancerTreatmentCapabilityModule,
-    RealWorldOncologyService
-};
 //# sourceMappingURL=index.js.map

package/dist/index.js.map CHANGED Viewed

	@@ -1 +1 @@
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package/package.json CHANGED Viewed

@@ -1,6 +1,6 @@
 {
   "name": "@erosolaraijs/cure",
-  "version": "1.0.3",
+  "version": "1.0.4",
   "description": "AI-powered unified cancer treatment framework with multi-provider support for medical research and patient care",
   "main": "dist/bin/cure.js",
   "type": "module",

package/src/bin/cure.ts CHANGED Viewed

@@ -8,7 +8,7 @@ import * as readline from 'readline';
 import * as https from 'https';
 import { CancerTreatmentCapabilityModule } from '../capabilities/cancerTreatmentCapability.js';
-const VERSION = '1.0.3';
+const VERSION = '1.0.4';
 const XAI_MODEL = 'grok-4-1-fast-reasoning';
 // ANSI color codes
@@ -27,6 +27,7 @@ const colors = {
 let cancerTreatment: CancerTreatmentCapabilityModule;
 let conversationHistory: Array<{role: string, content: string}> = [];
+let xaiApiKey: string | undefined = process.env.XAI_API_KEY;
 const SYSTEM_PROMPT = `You are Cure, an advanced AI oncologist assistant powered by the Cure Cancer Treatment Framework. You help doctors, researchers, and patients with:
@@ -57,12 +58,12 @@ Available commands the user can run:
 - /help - Show available commands`;
 async function callXAI(userMessage: string): Promise<string> {
-  const apiKey = process.env.XAI_API_KEY;
-  if (!apiKey) {
-    return `${colors.yellow}Note: Set XAI_API_KEY environment variable for AI-powered responses.${colors.reset}\n\nI can help you with cancer treatment analysis. Try:\n  /analyze P001 - Analyze patient\n  /plan P001 - Design treatment plan\n  /discover EGFR Lung - Find drug targets\n  /demo - Run demonstration`;
+  if (!xaiApiKey) {
+    return `${colors.yellow}API key not set.${colors.reset} Use ${colors.cyan}/key YOUR_API_KEY${colors.reset} to set your xAI API key.\n\nGet your key at: https://console.x.ai`;
   }
+  const apiKey = xaiApiKey;
   conversationHistory.push({ role: 'user', content: userMessage });
   const messages = [
@@ -166,9 +167,9 @@ async function launchInteractiveMode(): Promise<void> {
     process.stdout.write(`\n${colors.cyan}cure${colors.reset} ${colors.dim}>${colors.reset} `);
   };
-  const modelInfo = process.env.XAI_API_KEY
+  const modelInfo = xaiApiKey
     ? `${colors.green}Connected to xAI ${XAI_MODEL}${colors.reset}`
-    : `${colors.yellow}Set XAI_API_KEY for AI responses${colors.reset}`;
+    : `${colors.yellow}Use /key YOUR_API_KEY to enable AI${colors.reset}`;
   console.log(`${colors.dim}${modelInfo}${colors.reset}`);
   console.log(`${colors.dim}Type your question or /help for commands.${colors.reset}\n`);
@@ -237,7 +238,18 @@ async function processInput(input: string): Promise<void> {
         return;
       case 'model':
         console.log(`\n${colors.cyan}Model:${colors.reset} ${XAI_MODEL}`);
-        console.log(`${colors.cyan}API:${colors.reset} ${process.env.XAI_API_KEY ? 'Connected' : 'Not configured'}`);
+        console.log(`${colors.cyan}API:${colors.reset} ${xaiApiKey ? 'Connected' : 'Not configured'}`);
+        return;
+      case 'key':
+        if (args[0]) {
+          xaiApiKey = args[0];
+          console.log(`\n${colors.green}✓ API key set successfully${colors.reset}`);
+          console.log(`${colors.dim}You can now chat with the AI oncologist.${colors.reset}`);
+        } else {
+          console.log(`\n${colors.cyan}API Status:${colors.reset} ${xaiApiKey ? 'Connected' : 'Not set'}`);
+          console.log(`\n${colors.dim}Usage: /key YOUR_XAI_API_KEY${colors.reset}`);
+          console.log(`${colors.dim}Get your key at: https://console.x.ai${colors.reset}`);
+        }
         return;
       default:
         console.log(`\n${colors.red}Unknown command: /${cmd}${colors.reset}`);
@@ -389,6 +401,7 @@ function printInteractiveHelp(): void {
   console.log(`
 ${colors.bold}Commands${colors.reset}
 ${colors.dim}─────────────────────────────${colors.reset}
+  ${colors.cyan}/key${colors.reset} [api_key]         Set xAI API key
   ${colors.cyan}/analyze${colors.reset} [patient]     Analyze patient data
   ${colors.cyan}/plan${colors.reset} [patient]        Design treatment plan
   ${colors.cyan}/discover${colors.reset} [gene]       Drug target discovery
@@ -406,6 +419,11 @@ ${colors.dim}──────────────────────
   "Explain pembrolizumab mechanism of action"
   "What biomarkers predict response to immunotherapy?"
   "Compare osimertinib vs erlotinib for EGFR mutations"
+${colors.bold}Setup${colors.reset}
+${colors.dim}─────────────────────────────${colors.reset}
+  1. Get API key at https://console.x.ai
+  2. Run: /key YOUR_API_KEY
 `);
 }

package/src/index.ts ADDED Viewed

@@ -0,0 +1,268 @@
+/**
+ * AGI Core - Cure Cancer
+ *
+ * ██████╗██╗   ██╗██████╗ ███████╗     ██████╗ █████╗ ███╗   ██╗ ██████╗███████╗██████╗
+ * ██╔════╝██║   ██║██╔══██╗██╔════╝    ██╔════╝██╔══██╗████╗  ██║██╔════╝██╔════╝██╔══██╗
+ * ██║     ██║   ██║██████╔╝█████╗      ██║     ███████║██╔██╗ ██║██║     █████╗  ██████╔╝
+ * ██║     ██║   ██║██╔══██╗██╔══╝      ██║     ██╔══██║██║╚██╗██║██║     ██╔══╝  ██╔══██╗
+ * ╚██████╗╚██████╔╝██║  ██║███████╗    ╚██████╗██║  ██║██║ ╚████║╚██████╗███████╗██║  ██║
+ *  ╚═════╝ ╚═════╝ ╚═╝  ╚═╝╚══════╝     ╚═════╝╚═╝  ╚═╝╚═╝  ╚═══╝ ╚═════╝╚══════╝╚═╝  ╚═╝
+ *
+ * Comprehensive AI-powered precision oncology platform connecting:
+ * - Real genomic sequencing data (Foundation Medicine, Guardant, Tempus)
+ * - Hospital EHR systems (Epic, Cerner via HL7 FHIR)
+ * - Clinical trial registries (ClinicalTrials.gov)
+ * - HIPAA-compliant data handling
+ * - ML-powered outcome prediction
+ * - Drug safety and interaction checking
+ * - Clinician decision support
+ * - Patient portal interfaces
+ *
+ * @packageDocumentation
+ */
+// ═══════════════════════════════════════════════════════════════════════════════
+// CORE CAPABILITIES
+// ═══════════════════════════════════════════════════════════════════════════════
+export {
+  CancerTreatmentCapabilityModule,
+  type CancerTreatmentOperationType,
+  type CancerPatient,
+  type CancerTreatmentOperation,
+  type CancerTreatmentResult,
+  type TreatmentProtocol,
+  type DrugTarget,
+  type ImmunotherapyProtocol,
+  type CombinationTherapy,
+  type CancerCureResult
+} from './capabilities/cancerTreatmentCapability.js';
+// ═══════════════════════════════════════════════════════════════════════════════
+// REAL-WORLD ORCHESTRATION
+// ═══════════════════════════════════════════════════════════════════════════════
+import {
+  RealWorldOncologyService as RWOService,
+  createRealWorldOncologyService as createRWOService,
+  type RealWorldConfig as RWConfig,
+  type RealWorldPatient,
+  type ComprehensiveTreatmentPlan,
+  type TreatmentOutcome
+} from './orchestrator/realWorldOncology.js';
+export {
+  RWOService as RealWorldOncologyService,
+  createRWOService as createRealWorldOncologyService
+};
+export type {
+  RWConfig as RealWorldConfig,
+  RealWorldPatient,
+  ComprehensiveTreatmentPlan,
+  TreatmentOutcome
+};
+// ═══════════════════════════════════════════════════════════════════════════════
+// INTEGRATIONS
+// ═══════════════════════════════════════════════════════════════════════════════
+// EHR Integration (HL7 FHIR)
+export {
+  FHIRClient,
+  EpicFHIRClient,
+  CernerFHIRClient,
+  createFHIRClient,
+  type FHIRConfig,
+  type FHIRPatient,
+  type FHIRIdentifier,
+  type FHIRHumanName,
+  type FHIRAddress,
+  type FHIRContactPoint,
+  type FHIRCodeableConcept,
+  type FHIRCoding,
+  type FHIRExtension,
+  type FHIRCondition,
+  type FHIRObservation,
+  type FHIRQuantity,
+  type FHIRReference,
+  type FHIRMedicationRequest,
+  type FHIRDosage,
+  type FHIRDiagnosticReport,
+  type FHIRProcedure,
+  type FHIRBundle,
+  type FHIRResource,
+  type CancerDiagnosis,
+  type CancerBiomarkers,
+  type TreatmentHistory,
+  type AuditEvent
+} from './integrations/ehr/index.js';
+// Genomic Platforms
+export {
+  FoundationMedicineClient,
+  GuardantHealthClient,
+  TempusClient,
+  UnifiedGenomicsService,
+  createGenomicClient,
+  type GenomicTestOrder,
+  type GenomicTestResult,
+  type GenomicVariant,
+  type CopyNumberAlteration,
+  type GeneFusion,
+  type GenomicBiomarker,
+  type MSIResult,
+  type TMBResult,
+  type HRDResult,
+  type LOHResult,
+  type TherapyMatch,
+  type ClinicalTrialMatch,
+  type GenomicPlatformConfig
+} from './integrations/genomics/index.js';
+// Clinical Trials
+export {
+  ClinicalTrialsGovClient,
+  type ClinicalTrial,
+  type TrialStatus,
+  type TrialPhase,
+  type TrialIntervention,
+  type TrialEligibility,
+  type TrialLocation,
+  type TrialSponsor,
+  type TrialContact,
+  type TrialArm,
+  type TrialOutcome,
+  type BiomarkerRequirement,
+  type TrialSearchParams,
+  type TrialSearchResult,
+  type PatientProfile,
+  type TrialMatch
+} from './integrations/clinicalTrials/index.js';
+// ═══════════════════════════════════════════════════════════════════════════════
+// COMPLIANCE
+// ═══════════════════════════════════════════════════════════════════════════════
+export {
+  HIPAAComplianceService,
+  type AuditLogEntry,
+  type AuditEventType,
+  type AuditAction,
+  type PatientConsent,
+  type ConsentType,
+  type DataCategory,
+  type ConsentPurpose,
+  type AccessPolicy,
+  type AccessCondition,
+  type AccessDecision,
+  type EncryptionConfig,
+  type EncryptedData,
+  type DataMaskingConfig
+} from './compliance/index.js';
+// ═══════════════════════════════════════════════════════════════════════════════
+// MACHINE LEARNING
+// ═══════════════════════════════════════════════════════════════════════════════
+export {
+  OutcomePredictorService,
+  type PatientFeatures,
+  type TreatmentFeatures,
+  type ResponsePrediction,
+  type SurvivalPrediction,
+  type ToxicityPrediction,
+  type ResistancePrediction,
+  type TherapyRanking,
+  type MLModel,
+  type ModelRegistry
+} from './ml/index.js';
+// ═══════════════════════════════════════════════════════════════════════════════
+// SAFETY
+// ═══════════════════════════════════════════════════════════════════════════════
+export {
+  DrugSafetyService,
+  type Drug,
+  type CYP450Profile,
+  type DrugInteraction,
+  type Contraindication,
+  type DosingGuideline,
+  type AllergyCheck,
+  type SafetyAlert,
+  type PatientSafetyProfile
+} from './safety/index.js';
+// ═══════════════════════════════════════════════════════════════════════════════
+// VALIDATION
+// ═══════════════════════════════════════════════════════════════════════════════
+export {
+  RetrospectiveValidationService,
+  type ValidationPatient,
+  type SystemRecommendation,
+  type ValidationResult,
+  type CohortAnalysis
+} from './validation/index.js';
+// ═══════════════════════════════════════════════════════════════════════════════
+// CLINICIAN SUPPORT
+// ═══════════════════════════════════════════════════════════════════════════════
+export {
+  ClinicalDecisionSupportService,
+  type ClinicalRecommendation,
+  type ClinicianOverride,
+  type OverrideCategory,
+  type TumorBoardCase,
+  type AlertAcknowledgment
+} from './clinician/index.js';
+// ═══════════════════════════════════════════════════════════════════════════════
+// PATIENT PORTAL
+// ═══════════════════════════════════════════════════════════════════════════════
+export {
+  PatientPortalService,
+  type PatientAccount,
+  type PatientTreatmentSummary,
+  type SymptomReport,
+  type MedicationAdherenceLog,
+  type QualityOfLifeAssessment,
+  type PatientMessage,
+  type EducationalContent,
+  type AppointmentRequest
+} from './patient/index.js';
+// ═══════════════════════════════════════════════════════════════════════════════
+// QUICK START FACTORY
+// ═══════════════════════════════════════════════════════════════════════════════
+/**
+ * Quick start factory to create a fully configured oncology service
+ *
+ * @example
+ * ```typescript
+ * import { createOncologyPlatform } from 'agi-core-cure-cancer';
+ *
+ * const platform = await createOncologyPlatform({
+ *   ehr: {
+ *     enabled: true,
+ *     vendor: 'epic',
+ *     baseUrl: 'https://epic.hospital.org/fhir',
+ *     clientId: 'your-client-id'
+ *   },
+ *   genomics: {
+ *     enabled: true,
+ *     platforms: ['foundation', 'guardant']
+ *   }
+ * });
+ *
+ * const plan = await platform.generateComprehensivePlan(patient, 'DR001');
+ * ```
+ */
+export async function createOncologyPlatform(config?: Partial<RWConfig>): Promise<RWOService> {
+  const service = createRWOService(config);
+  await service.initialize();
+  return service;
+}