@datagrok/bio 2.11.30 → 2.11.34

package/dist/79.js.map

@@ -1 +1 @@
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const monomerWorksConsts = {\n    // constants for parsing molfile V2000\n    V2K_RGP_SHIFT: 8,\n    V2K_RGP_LINE: 'M  RGP',\n    V2K_A_LINE: 'A  ',\n    // constants for parsing/reconstruction of molfile V3000\n    V3K_COUNTS_SHIFT: 14,\n    V3K_IDX_SHIFT: 7,\n    V3K_HEADER_FIRST_LINE: '\\nDatagrok macromolecule handler\\n\\n',\n    V3K_HEADER_SECOND_LINE: '  0  0  0  0  0  0            999 V3000\\n',\n    V3K_BEGIN_CTAB_BLOCK: 'M  V30 BEGIN CTAB\\n',\n    V3K_END_CTAB_BLOCK: 'M  V30 END CTAB\\n',\n    V3K_BEGIN_COUNTS_LINE: 'M  V30 COUNTS ',\n    V3K_COUNTS_LINE_ENDING: ' 0 0 0\\n',\n    V3K_BEGIN_ATOM_BLOCK: 'M  V30 BEGIN ATOM\\n',\n    V3K_END_ATOM_BLOCK: 'M  V30 END ATOM\\n',\n    V3K_BEGIN_BOND_BLOCK: 'M  V30 BEGIN BOND\\n',\n    V3K_END_BOND_BLOCK: 'M  V30 END BOND\\n',\n    V3K_BOND_CONFIG: ' CFG=',\n    V3K_BEGIN_DATA_LINE: 'M  V30 ',\n    V3K_END: 'M  END',\n    PRECISION_FACTOR: 10000,\n    // symbols for the corresponding monomers in HELM library\n    DEOXYRIBOSE: 'd',\n    RIBOSE: 'r',\n    PHOSPHATE: 'p',\n    OXYGEN: 'O',\n    HYDROGEN: 'H',\n};\n//# sourceMappingURL=consts.js.map","import { monomerWorksConsts as C } from './consts';\nimport { HELM_CORE_FIELDS, } from '../utils/const';\n/** Get a mapping of peptide symbols to HELM monomer library objects with selected fields.\n * @param {IMonomerLib} monomerLib - Monomer library\n * @param {HELM_POLYMER_TYPE} polymerType - Polymer type\n * @param {ALPHABET} alphabet - Alphabet of the column\n * @return {Map<string, any>} - Mapping of peptide symbols to HELM monomer library objects with selected fields*/\nexport function getFormattedMonomerLib(monomerLib, polymerType, alphabet) {\n    const map = new Map();\n    for (const monomerSymbol of monomerLib.getMonomerSymbolsByType(polymerType)) {\n        const it = monomerLib.getMonomer(polymerType, monomerSymbol);\n        if (polymerType === \"RNA\" /* HELM_POLYMER_TYPE.RNA */ &&\n            (it[\"monomerType\" /* HELM_FIELDS.MONOMER_TYPE */] === \"Branch\" /* HELM_MONOMER_TYPE.BRANCH */ ||\n                alphabet === \"DNA\" /* ALPHABET.DNA */ && it[\"symbol\" /* HELM_FIELDS.SYMBOL */] === C.DEOXYRIBOSE ||\n                alphabet === \"RNA\" /* ALPHABET.RNA */ && it[\"symbol\" /* HELM_FIELDS.SYMBOL */] === C.RIBOSE ||\n                it[\"symbol\" /* HELM_FIELDS.SYMBOL */] === C.PHOSPHATE) ||\n            polymerType === \"PEPTIDE\" /* HELM_POLYMER_TYPE.PEPTIDE */ &&\n                it[\"monomerType\" /* HELM_FIELDS.MONOMER_TYPE */] !== \"Branch\" /* HELM_MONOMER_TYPE.BRANCH */) {\n            const monomerObject = {};\n            HELM_CORE_FIELDS.forEach((field) => {\n                //@ts-ignore\n                monomerObject[field] = it[field];\n            });\n            map.set(it[\"symbol\" /* HELM_FIELDS.SYMBOL */], monomerObject);\n        }\n    }\n    return map;\n}\n/** Translate a sequence of monomer symbols into Molfile V3000\n * @param {string[]} monomerSeq - Sequence of monomer symbols\n * @param {Map<string, MolGraph>} monomersDict - Mapping of monomer symbols to MolGraph objects\n * @param {ALPHABET} alphabet - Alphabet of the column\n * @param {HELM_POLYMER_TYPE} polymerType - Polymer type\n * @return {string} - Molfile V3000*/\nexport function monomerSeqToMolfile(monomerSeq, monomersDict, alphabet, polymerType) {\n    if (monomerSeq.length === 0) {\n        // throw new Error('monomerSeq is empty');\n        return '';\n    }\n    // define atom and bond counts, taking into account the bond type\n    const getAtomAndBondCounts = getResultingAtomBondCounts;\n    const { atomCount, bondCount } = getAtomAndBondCounts(monomerSeq, monomersDict, alphabet, polymerType);\n    // create arrays to store lines of the resulting molfile\n    const molfileAtomBlock = new Array(atomCount);\n    const molfileBondBlock = new Array(bondCount);\n    let addMonomerToMolblock; // todo: types?\n    let sugar = null;\n    let phosphate = null;\n    if (polymerType === \"PEPTIDE\" /* HELM_POLYMER_TYPE.PEPTIDE */) {\n        addMonomerToMolblock = addAminoAcidToMolblock;\n    }\n    else { // nucleotides\n        addMonomerToMolblock = addNucleotideToMolblock;\n        sugar = (alphabet === \"DNA\" /* ALPHABET.DNA */) ? monomersDict.get(C.DEOXYRIBOSE) : monomersDict.get(C.RIBOSE);\n        phosphate = monomersDict.get(C.PHOSPHATE);\n    }\n    const v = {\n        i: 0,\n        nodeShift: 0,\n        bondShift: 0,\n        backbonePositionShift: new Array(2).fill(0),\n        branchPositionShift: new Array(2).fill(0),\n        backboneAttachNode: 0,\n        branchAttachNode: 0,\n        flipFactor: 1,\n    };\n    const LC = {\n        sugar: sugar,\n        phosphate: phosphate,\n        seqLength: monomerSeq.length,\n        atomCount: atomCount,\n        bondCount: bondCount,\n    };\n    for (v.i = 0; v.i < LC.seqLength; ++v.i) {\n        const monomer = monomersDict.get(monomerSeq[v.i]);\n        addMonomerToMolblock(monomer, molfileAtomBlock, molfileBondBlock, v, LC);\n    }\n    capResultingMolblock(molfileAtomBlock, molfileBondBlock, v, LC);\n    const molfileCountsLine = C.V3K_BEGIN_COUNTS_LINE + atomCount + ' ' + bondCount + C.V3K_COUNTS_LINE_ENDING;\n    // todo: possible optimization may be achieved by replacing .join('') with +=\n    // since counterintuitively joining an array into a new string is reportedly\n    // slower than using += as below\n    let result = '';\n    result += C.V3K_HEADER_FIRST_LINE;\n    result += C.V3K_HEADER_SECOND_LINE;\n    result += C.V3K_BEGIN_CTAB_BLOCK;\n    result += molfileCountsLine;\n    result += C.V3K_BEGIN_ATOM_BLOCK;\n    result += molfileAtomBlock.join('');\n    result += C.V3K_END_ATOM_BLOCK;\n    result += C.V3K_BEGIN_BOND_BLOCK;\n    result += molfileBondBlock.join('');\n    result += C.V3K_END_BOND_BLOCK;\n    result += C.V3K_END_CTAB_BLOCK;\n    result += C.V3K_END;\n    // return molfileParts.join('');\n    return result;\n}\n/** Cap the resulting (after sewing up all the monomers) molfile with 'O'\n * @param {string[]} molfileAtomBlock - Array of lines of the resulting molfile atom block\n * @param {string[]} molfileBondBlock - Array of lines of the resulting molfile bond block\n * @param {LoopVariables} v - Loop variables\n * @param {LoopConstants} LC - Loop constants*/\nfunction capResultingMolblock(molfileAtomBlock, molfileBondBlock, v, LC) {\n    // add terminal oxygen\n    const atomIdx = v.nodeShift + 1;\n    molfileAtomBlock[LC.atomCount] = C.V3K_BEGIN_DATA_LINE + atomIdx + ' ' +\n        C.OXYGEN + ' ' + keepPrecision(v.backbonePositionShift[0]) + ' ' +\n        v.flipFactor * keepPrecision(v.backbonePositionShift[1]) + ' ' + '0.000000 0' + '\\n';\n    // add terminal bond\n    const firstAtom = v.backboneAttachNode;\n    const secondAtom = atomIdx;\n    molfileBondBlock[LC.bondCount] = C.V3K_BEGIN_DATA_LINE + v.bondShift + ' ' +\n        1 + ' ' + firstAtom + ' ' + secondAtom + '\\n';\n}\nfunction addAminoAcidToMolblock(monomer, molfileAtomBlock, molfileBondBlock, v) {\n    v.flipFactor = (-1) ** (v.i % 2); // to flip every even monomer over OX\n    addBackboneMonomerToMolblock(monomer, molfileAtomBlock, molfileBondBlock, v);\n}\nfunction addBackboneMonomerToMolblock(monomer, molfileAtomBlock, molfileBondBlock, v) {\n    // todo: remove these comments to the docstrings of the corr. functions\n    // construnct the lines of V3K molfile atom block\n    fillAtomLines(monomer, molfileAtomBlock, v);\n    // construct the lines of V3K molfile bond block\n    fillBondLines(monomer, molfileBondBlock, v);\n    // peptide bond\n    fillChainExtendingBond(monomer, molfileBondBlock, v);\n    // update branch variables if necessary\n    if (monomer.meta.branchShift !== null && monomer.meta.terminalNodes.length > 2)\n        updateBranchVariables(monomer, v);\n    // update loop variables\n    updateChainExtendingVariables(monomer, v);\n}\nfunction addNucleotideToMolblock(nucleobase, molfileAtomBlock, molfileBondBlock, v, LC) {\n    // construnct the lines of V3K molfile atom block corresponding to phosphate\n    // and sugar\n    if (v.i === 0) {\n        addBackboneMonomerToMolblock(LC.sugar, molfileAtomBlock, molfileBondBlock, v);\n    }\n    else {\n        for (const monomer of [LC.phosphate, LC.sugar])\n            addBackboneMonomerToMolblock(monomer, molfileAtomBlock, molfileBondBlock, v);\n    }\n    addBranchMonomerToMolblock(nucleobase, molfileAtomBlock, molfileBondBlock, v);\n}\nfunction addBranchMonomerToMolblock(monomer, molfileAtomBlock, molfileBondBlock, v) {\n    fillBranchAtomLines(monomer, molfileAtomBlock, v);\n    fillBondLines(monomer, molfileBondBlock, v);\n    fillBackboneToBranchBond(monomer, molfileBondBlock, v);\n    // C-N bond\n    const bondIdx = v.bondShift;\n    const firstAtom = v.branchAttachNode;\n    const secondAtom = monomer.meta.terminalNodes[0] + v.nodeShift;\n    molfileBondBlock[bondIdx - 1] = C.V3K_BEGIN_DATA_LINE + bondIdx + ' ' +\n        1 + ' ' + firstAtom + ' ' + secondAtom + '\\n';\n    // update loop variables\n    v.bondShift += monomer.bonds.atomPairs.length + 1;\n    v.nodeShift += monomer.atoms.atomTypes.length;\n}\nfunction updateChainExtendingVariables(monomer, v) {\n    v.backboneAttachNode = v.nodeShift + monomer.meta.terminalNodes[1];\n    v.bondShift += monomer.bonds.atomPairs.length + 1;\n    v.nodeShift += monomer.atoms.atomTypes.length;\n    v.backbonePositionShift[0] += monomer.meta.backboneShift[0]; // todo: non-null check\n    v.backbonePositionShift[1] += v.flipFactor * monomer.meta.backboneShift[1];\n}\nfunction updateBranchVariables(monomer, v) {\n    v.branchAttachNode = v.nodeShift + monomer.meta.terminalNodes[2];\n    for (let i = 0; i < 2; ++i)\n        v.branchPositionShift[i] = v.backbonePositionShift[i] + monomer.meta.branchShift[i];\n}\nfunction fillAtomLines(monomer, molfileAtomBlock, v) {\n    for (let j = 0; j < monomer.atoms.atomTypes.length; ++j) {\n        const atomIdx = v.nodeShift + j + 1;\n        molfileAtomBlock[v.nodeShift + j] = C.V3K_BEGIN_DATA_LINE + atomIdx + ' ' +\n            monomer.atoms.atomTypes[j] + ' ' +\n            keepPrecision(v.backbonePositionShift[0] + monomer.atoms.x[j]) + ' ' +\n            keepPrecision(v.backbonePositionShift[1] + v.flipFactor * monomer.atoms.y[j]) +\n            ' ' + monomer.atoms.kwargs[j];\n    }\n}\n// todo: remove as quickfix\nfunction fillBranchAtomLines(monomer, molfileAtomBlock, v) {\n    for (let j = 0; j < monomer.atoms.atomTypes.length; ++j) {\n        const atomIdx = v.nodeShift + j + 1;\n        molfileAtomBlock[v.nodeShift + j] = C.V3K_BEGIN_DATA_LINE + atomIdx + ' ' +\n            monomer.atoms.atomTypes[j] + ' ' +\n            keepPrecision(v.branchPositionShift[0] + monomer.atoms.x[j]) + ' ' +\n            keepPrecision(v.branchPositionShift[1] + v.flipFactor * monomer.atoms.y[j]) +\n            ' ' + monomer.atoms.kwargs[j];\n    }\n}\nfunction fillBondLines(monomer, molfileBondBlock, v) {\n    // construct the lines of V3K molfile bond block\n    for (let j = 0; j < monomer.bonds.atomPairs.length; ++j) {\n        const bondIdx = v.bondShift + j + 1;\n        const firstAtom = monomer.bonds.atomPairs[j][0] + v.nodeShift;\n        const secondAtom = monomer.bonds.atomPairs[j][1] + v.nodeShift;\n        let bondCfg = '';\n        if (monomer.bonds.bondConfiguration.has(j)) {\n            // flip orientation when necessary\n            let orientation = monomer.bonds.bondConfiguration.get(j);\n            if (v.flipFactor < 0)\n                orientation = (orientation === 1) ? 3 : 1;\n            bondCfg = ' CFG=' + orientation;\n        }\n        const kwargs = monomer.bonds.kwargs.has(j) ?\n            ' ' + monomer.bonds.kwargs.get(j) : '';\n        molfileBondBlock[v.bondShift + j] = C.V3K_BEGIN_DATA_LINE + bondIdx + ' ' +\n            monomer.bonds.bondTypes[j] + ' ' +\n            firstAtom + ' ' + secondAtom + bondCfg + kwargs + '\\n';\n    }\n}\nfunction fillChainExtendingBond(monomer, molfileBondBlock, v) {\n    if (v.backboneAttachNode !== 0) {\n        const bondIdx = v.bondShift;\n        const firstAtom = v.backboneAttachNode;\n        const secondAtom = monomer.meta.terminalNodes[0] + v.nodeShift;\n        molfileBondBlock[v.bondShift - 1] = C.V3K_BEGIN_DATA_LINE + bondIdx + ' ' +\n            1 + ' ' + firstAtom + ' ' + secondAtom + '\\n';\n    }\n}\n// todo: remove\nfunction fillBackboneToBranchBond(branchMonomer, molfileBondBlock, v) {\n    const bondIdx = v.bondShift;\n    const firstAtom = v.branchAttachNode;\n    const secondAtom = branchMonomer.meta.terminalNodes[0] + v.nodeShift;\n    molfileBondBlock[bondIdx - 1] = C.V3K_BEGIN_DATA_LINE + bondIdx + ' ' +\n        1 + ' ' + firstAtom + ' ' + secondAtom + '\\n';\n}\n/** Compute the atom/bond counts for the resulting molfile, depending on the\n    * type of polymer (peptide/nucleotide)\n    * @param {string[]}monomerSeq - the sequence of monomers\n    * @param {Map<string, MolGraph>}monomersDict - the dictionary of monomers\n    * @param {ALPHABET}alphabet - the alphabet of the monomers\n    * @param {HELM_POLYMER_TYPE}polymerType - the type of polymer\n    * @return {{atomCount: number, bondCount: number}} - the atom/bond counts*/\nfunction getResultingAtomBondCounts(monomerSeq, monomersDict, alphabet, polymerType) {\n    let atomCount = 0;\n    let bondCount = 0;\n    // sum up all the atoms/nodes provided by the sequence\n    for (const monomerSymbol of monomerSeq) {\n        if (monomerSymbol === '')\n            continue; // Skip for gap/empty monomer in MSA\n        const monomer = monomersDict.get(monomerSymbol);\n        atomCount += monomer.atoms.x.length;\n        bondCount += monomer.bonds.bondTypes.length;\n    }\n    // add extra values depending on the polymer type\n    if (polymerType === \"PEPTIDE\" /* HELM_POLYMER_TYPE.PEPTIDE */) {\n        // add the rightmost/terminating cap group 'OH' (i.e. 'O')\n        atomCount += 1;\n        // add chain-extending bonds (C-NH per each monomer pair and terminal C-OH)\n        bondCount += monomerSeq.length;\n    }\n    else { // nucleotides\n        const sugar = (alphabet === \"DNA\" /* ALPHABET.DNA */) ?\n            monomersDict.get(C.DEOXYRIBOSE) : monomersDict.get(C.RIBOSE);\n        const phosphate = monomersDict.get(C.PHOSPHATE);\n        // add phosphate per each pair of nucleobase symbols\n        atomCount += (monomerSeq.length - 1) * phosphate.atoms.x.length;\n        // add sugar per each nucleobase symbol\n        atomCount += monomerSeq.length * sugar.atoms.x.length;\n        // add the leftmost cap group 'OH' (i.e. 'O')\n        atomCount += 1;\n        // add bonds from phosphate monomers\n        bondCount += (monomerSeq.length - 1) * phosphate.bonds.bondTypes.length;\n        // add bonds from sugar monomers\n        bondCount += monomerSeq.length * sugar.bonds.bondTypes.length;\n        // exclude the first chain-extending bond O-P (absent, no 'leftmost' phosphate)\n        bondCount -= 1;\n        // add chain-extending and branch bonds (O-P, C-O and C-N per each nucleotide)\n        bondCount += monomerSeq.length * 3;\n    }\n    return { atomCount, bondCount };\n}\n/** Keep precision upon floating point operations over atom coordinates\n * @param {number}x - the floating point number\n * @return {number} - the floating point number with the same precision\n*/\nexport function keepPrecision(x) {\n    return Math.round(C.PRECISION_FACTOR * x) / C.PRECISION_FACTOR;\n}\n//# sourceMappingURL=to-atomic-level-utils.js.map","export const HELM_CORE_LIB_FILENAME = '/data/HELMCoreLibrary.json';\n// core fields of HELM library object used in toAtomicLevel function\nexport const HELM_CORE_FIELDS = [\n    \"symbol\" /* HELM_FIELDS.SYMBOL */,\n    \"molfile\" /* HELM_FIELDS.MOLFILE */,\n    \"rgroups\" /* HELM_FIELDS.RGROUPS */,\n    \"name\" /* HELM_FIELDS.NAME */,\n    // HELM_FIELDS.MONOMER_TYPE, // add if terminal monomers for PEPTIDEs to be\n    // supported\n];\nexport const SDF_MONOMER_NAME = 'MonomerName';\n/** For PolyTool  */\nexport const helmFieldsToPolyToolInputFields = {\n    [\"symbol\" /* HELM_REQUIRED_FIELDS.SYMBOL */]: 'Short Name',\n    [\"name\" /* HELM_REQUIRED_FIELDS.NAME */]: 'Medium Name',\n    [\"smiles\" /* HELM_REQUIRED_FIELDS.SMILES */]: 'SMILES',\n};\n/** For PolyTool  */\nexport const R_GROUP_BLOCK_DUMMY = [\n    {\n        'capGroupSmiles': '[*:1][H]',\n        'alternateId': 'R1-H',\n        'capGroupName': 'H',\n        'label': 'R1'\n    },\n    {\n        'capGroupSmiles': 'O[*:2]',\n        'alternateId': 'R2-OH',\n        'capGroupName': 'OH',\n        'label': 'R2'\n    },\n    {\n        'capGroupSmiles': '[*:3][H]',\n        'alternateId': 'R3-H',\n        'capGroupName': 'H',\n        'label': 'R3'\n    }\n];\n// todo: ideally, keys should be expressed via constants\nexport const jsonSdfMonomerLibDict = {\n    'monomerType': null,\n    'smiles': null,\n    'name': 'MonomerName',\n    'author': null,\n    'molfile': 'molecule',\n    'naturalAnalog': 'MonomerNaturalAnalogCode',\n    'rgroups': 'MonomerCaps',\n    'createDate': null,\n    'id': null,\n    'polymerType': 'MonomerType',\n    'symbol': 'MonomerCode'\n};\nexport const DUMMY_MONOMER = {\n    'monomerType': 'Backbone',\n    'smiles': '',\n    'name': '',\n    'author': 'Datagrok',\n    'molfile': '',\n    'naturalAnalog': '',\n    'rgroups': [],\n    'createDate': null,\n    'id': 0,\n    'polymerType': 'PEPTIDE',\n    'symbol': ''\n};\n// range of hex nubers used in PepSea library to endode monomers\nexport const MONOMER_ENCODE_MIN = 0x100;\nexport const MONOMER_ENCODE_MAX = 0x40A;\nexport const RIBOSE_SYMBOL = 'r';\nexport const DEOXYRIBOSE_SYMBOL = 'd';\nexport const PHOSPHATE_SYMBOL = 'p';\nexport const HELM_WRAPPERS_REGEXP = new RegExp(`[${RIBOSE_SYMBOL}${DEOXYRIBOSE_SYMBOL}]\\\\((\\\\w)\\\\)${PHOSPHATE_SYMBOL}?`, 'g');\n//# sourceMappingURL=const.js.map","import { monomerSeqToMolfile } from './to-atomic-level-utils';\nonmessage = 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const monomerWorksConsts = {\n    // constants for parsing molfile V2000\n    V2K_RGP_SHIFT: 8,\n    V2K_RGP_LINE: 'M  RGP',\n    V2K_A_LINE: 'A  ',\n    // constants for parsing/reconstruction of molfile V3000\n    V3K_COUNTS_SHIFT: 14,\n    V3K_IDX_SHIFT: 7,\n    V3K_HEADER_FIRST_LINE: '\\nDatagrok macromolecule handler\\n\\n',\n    V3K_HEADER_SECOND_LINE: '  0  0  0  0  0  0            999 V3000\\n',\n    V3K_BEGIN_CTAB_BLOCK: 'M  V30 BEGIN CTAB\\n',\n    V3K_END_CTAB_BLOCK: 'M  V30 END CTAB\\n',\n    V3K_BEGIN_COUNTS_LINE: 'M  V30 COUNTS ',\n    V3K_COUNTS_LINE_ENDING: ' 0 0 0\\n',\n    V3K_BEGIN_ATOM_BLOCK: 'M  V30 BEGIN ATOM\\n',\n    V3K_END_ATOM_BLOCK: 'M  V30 END ATOM\\n',\n    V3K_BEGIN_BOND_BLOCK: 'M  V30 BEGIN BOND\\n',\n    V3K_END_BOND_BLOCK: 'M  V30 END BOND\\n',\n    V3K_BOND_CONFIG: ' CFG=',\n    V3K_BEGIN_DATA_LINE: 'M  V30 ',\n    V3K_END: 'M  END',\n    PRECISION_FACTOR: 10000,\n    // symbols for the corresponding monomers in HELM library\n    DEOXYRIBOSE: 'd',\n    RIBOSE: 'r',\n    PHOSPHATE: 'p',\n    OXYGEN: 'O',\n    HYDROGEN: 'H',\n};\n//# sourceMappingURL=consts.js.map","import { monomerWorksConsts as C } from './consts';\nimport { HELM_CORE_FIELDS, } from '../utils/const';\n/** Get a mapping of peptide symbols to HELM monomer library objects with selected fields.\n * @param {IMonomerLib} monomerLib - Monomer library\n * @param {HELM_POLYMER_TYPE} polymerType - Polymer type\n * @param {ALPHABET} alphabet - Alphabet of the column\n * @return {Map<string, any>} - Mapping of peptide symbols to HELM monomer library objects with selected fields*/\nexport function getFormattedMonomerLib(monomerLib, polymerType, alphabet) {\n    const map = new Map();\n    for (const monomerSymbol of monomerLib.getMonomerSymbolsByType(polymerType)) {\n        const it = monomerLib.getMonomer(polymerType, monomerSymbol);\n        if (polymerType === \"RNA\" /* HELM_POLYMER_TYPE.RNA */ &&\n            (it[\"monomerType\" /* HELM_FIELDS.MONOMER_TYPE */] === \"Branch\" /* HELM_MONOMER_TYPE.BRANCH */ ||\n                alphabet === \"DNA\" /* ALPHABET.DNA */ && it[\"symbol\" /* HELM_FIELDS.SYMBOL */] === C.DEOXYRIBOSE ||\n                alphabet === \"RNA\" /* ALPHABET.RNA */ && it[\"symbol\" /* HELM_FIELDS.SYMBOL */] === C.RIBOSE ||\n                it[\"symbol\" /* HELM_FIELDS.SYMBOL */] === C.PHOSPHATE) ||\n            polymerType === \"PEPTIDE\" /* HELM_POLYMER_TYPE.PEPTIDE */ &&\n                it[\"monomerType\" /* HELM_FIELDS.MONOMER_TYPE */] !== \"Branch\" /* HELM_MONOMER_TYPE.BRANCH */) {\n            const monomerObject = {};\n            HELM_CORE_FIELDS.forEach((field) => {\n                //@ts-ignore\n                monomerObject[field] = it[field];\n            });\n            map.set(it[\"symbol\" /* HELM_FIELDS.SYMBOL */], monomerObject);\n        }\n    }\n    return map;\n}\n/** Translate a sequence of monomer symbols into Molfile V3000\n * @param {string[]} monomerSeq - Sequence of monomer symbols\n * @param {Map<string, MolGraph>} monomersDict - Mapping of monomer symbols to MolGraph objects\n * @param {ALPHABET} alphabet - Alphabet of the column\n * @param {HELM_POLYMER_TYPE} polymerType - Polymer type\n * @return {string} - Molfile V3000*/\nexport function monomerSeqToMolfile(monomerSeq, monomersDict, alphabet, polymerType) {\n    if (monomerSeq.length === 0) {\n        // throw new Error('monomerSeq is empty');\n        return '';\n    }\n    // define atom and bond counts, taking into account the bond type\n    const getAtomAndBondCounts = getResultingAtomBondCounts;\n    const { atomCount, bondCount } = getAtomAndBondCounts(monomerSeq, monomersDict, alphabet, polymerType);\n    // create arrays to store lines of the resulting molfile\n    const molfileAtomBlock = new Array(atomCount);\n    const molfileBondBlock = new Array(bondCount);\n    let addMonomerToMolblock; // todo: types?\n    let sugar = null;\n    let phosphate = null;\n    if (polymerType === \"PEPTIDE\" /* HELM_POLYMER_TYPE.PEPTIDE */) {\n        addMonomerToMolblock = addAminoAcidToMolblock;\n    }\n    else { // nucleotides\n        addMonomerToMolblock = addNucleotideToMolblock;\n        sugar = (alphabet === \"DNA\" /* ALPHABET.DNA */) ? monomersDict.get(C.DEOXYRIBOSE) : monomersDict.get(C.RIBOSE);\n        phosphate = monomersDict.get(C.PHOSPHATE);\n    }\n    const v = {\n        i: 0,\n        nodeShift: 0,\n        bondShift: 0,\n        backbonePositionShift: new Array(2).fill(0),\n        branchPositionShift: new Array(2).fill(0),\n        backboneAttachNode: 0,\n        branchAttachNode: 0,\n        flipFactor: 1,\n    };\n    const LC = {\n        sugar: sugar,\n        phosphate: phosphate,\n        seqLength: monomerSeq.length,\n        atomCount: atomCount,\n        bondCount: bondCount,\n    };\n    for (v.i = 0; v.i < LC.seqLength; ++v.i) {\n        const monomer = monomersDict.get(monomerSeq[v.i]);\n        addMonomerToMolblock(monomer, molfileAtomBlock, molfileBondBlock, v, LC);\n    }\n    capResultingMolblock(molfileAtomBlock, molfileBondBlock, v, LC);\n    const molfileCountsLine = C.V3K_BEGIN_COUNTS_LINE + atomCount + ' ' + bondCount + C.V3K_COUNTS_LINE_ENDING;\n    // todo: possible optimization may be achieved by replacing .join('') with +=\n    // since counterintuitively joining an array into a new string is reportedly\n    // slower than using += as below\n    let result = '';\n    result += C.V3K_HEADER_FIRST_LINE;\n    result += C.V3K_HEADER_SECOND_LINE;\n    result += C.V3K_BEGIN_CTAB_BLOCK;\n    result += molfileCountsLine;\n    result += C.V3K_BEGIN_ATOM_BLOCK;\n    result += molfileAtomBlock.join('');\n    result += C.V3K_END_ATOM_BLOCK;\n    result += C.V3K_BEGIN_BOND_BLOCK;\n    result += molfileBondBlock.join('');\n    result += C.V3K_END_BOND_BLOCK;\n    result += C.V3K_END_CTAB_BLOCK;\n    result += C.V3K_END;\n    // return molfileParts.join('');\n    return result;\n}\n/** Cap the resulting (after sewing up all the monomers) molfile with 'O'\n * @param {string[]} molfileAtomBlock - Array of lines of the resulting molfile atom block\n * @param {string[]} molfileBondBlock - Array of lines of the resulting molfile bond block\n * @param {LoopVariables} v - Loop variables\n * @param {LoopConstants} LC - Loop constants*/\nfunction capResultingMolblock(molfileAtomBlock, molfileBondBlock, v, LC) {\n    // add terminal oxygen\n    const atomIdx = v.nodeShift + 1;\n    molfileAtomBlock[LC.atomCount] = C.V3K_BEGIN_DATA_LINE + atomIdx + ' ' +\n        C.OXYGEN + ' ' + keepPrecision(v.backbonePositionShift[0]) + ' ' +\n        v.flipFactor * keepPrecision(v.backbonePositionShift[1]) + ' ' + '0.000000 0' + '\\n';\n    // add terminal bond\n    const firstAtom = v.backboneAttachNode;\n    const secondAtom = atomIdx;\n    molfileBondBlock[LC.bondCount] = C.V3K_BEGIN_DATA_LINE + v.bondShift + ' ' +\n        1 + ' ' + firstAtom + ' ' + secondAtom + '\\n';\n}\nfunction addAminoAcidToMolblock(monomer, molfileAtomBlock, molfileBondBlock, v) {\n    v.flipFactor = (-1) ** (v.i % 2); // to flip every even monomer over OX\n    addBackboneMonomerToMolblock(monomer, molfileAtomBlock, molfileBondBlock, v);\n}\nfunction addBackboneMonomerToMolblock(monomer, molfileAtomBlock, molfileBondBlock, v) {\n    // todo: remove these comments to the docstrings of the corr. functions\n    // construnct the lines of V3K molfile atom block\n    fillAtomLines(monomer, molfileAtomBlock, v);\n    // construct the lines of V3K molfile bond block\n    fillBondLines(monomer, molfileBondBlock, v);\n    // peptide bond\n    fillChainExtendingBond(monomer, molfileBondBlock, v);\n    // update branch variables if necessary\n    if (monomer.meta.branchShift !== null && monomer.meta.terminalNodes.length > 2)\n        updateBranchVariables(monomer, v);\n    // update loop variables\n    updateChainExtendingVariables(monomer, v);\n}\nfunction addNucleotideToMolblock(nucleobase, molfileAtomBlock, molfileBondBlock, v, LC) {\n    // construnct the lines of V3K molfile atom block corresponding to phosphate\n    // and sugar\n    if (v.i === 0) {\n        addBackboneMonomerToMolblock(LC.sugar, molfileAtomBlock, molfileBondBlock, v);\n    }\n    else {\n        for (const monomer of [LC.phosphate, LC.sugar])\n            addBackboneMonomerToMolblock(monomer, molfileAtomBlock, molfileBondBlock, v);\n    }\n    addBranchMonomerToMolblock(nucleobase, molfileAtomBlock, molfileBondBlock, v);\n}\nfunction addBranchMonomerToMolblock(monomer, molfileAtomBlock, molfileBondBlock, v) {\n    fillBranchAtomLines(monomer, molfileAtomBlock, v);\n    fillBondLines(monomer, molfileBondBlock, v);\n    fillBackboneToBranchBond(monomer, molfileBondBlock, v);\n    // C-N bond\n    const bondIdx = v.bondShift;\n    const firstAtom = v.branchAttachNode;\n    const secondAtom = monomer.meta.terminalNodes[0] + v.nodeShift;\n    molfileBondBlock[bondIdx - 1] = C.V3K_BEGIN_DATA_LINE + bondIdx + ' ' +\n        1 + ' ' + firstAtom + ' ' + secondAtom + '\\n';\n    // update loop variables\n    v.bondShift += monomer.bonds.atomPairs.length + 1;\n    v.nodeShift += monomer.atoms.atomTypes.length;\n}\nfunction updateChainExtendingVariables(monomer, v) {\n    v.backboneAttachNode = v.nodeShift + monomer.meta.terminalNodes[1];\n    v.bondShift += monomer.bonds.atomPairs.length + 1;\n    v.nodeShift += monomer.atoms.atomTypes.length;\n    v.backbonePositionShift[0] += monomer.meta.backboneShift[0]; // todo: non-null check\n    v.backbonePositionShift[1] += v.flipFactor * monomer.meta.backboneShift[1];\n}\nfunction updateBranchVariables(monomer, v) {\n    v.branchAttachNode = v.nodeShift + monomer.meta.terminalNodes[2];\n    for (let i = 0; i < 2; ++i)\n        v.branchPositionShift[i] = v.backbonePositionShift[i] + monomer.meta.branchShift[i];\n}\nfunction fillAtomLines(monomer, molfileAtomBlock, v) {\n    for (let j = 0; j < monomer.atoms.atomTypes.length; ++j) {\n        const atomIdx = v.nodeShift + j + 1;\n        molfileAtomBlock[v.nodeShift + j] = C.V3K_BEGIN_DATA_LINE + atomIdx + ' ' +\n            monomer.atoms.atomTypes[j] + ' ' +\n            keepPrecision(v.backbonePositionShift[0] + monomer.atoms.x[j]) + ' ' +\n            keepPrecision(v.backbonePositionShift[1] + v.flipFactor * monomer.atoms.y[j]) +\n            ' ' + monomer.atoms.kwargs[j];\n    }\n}\n// todo: remove as quickfix\nfunction fillBranchAtomLines(monomer, molfileAtomBlock, v) {\n    for (let j = 0; j < monomer.atoms.atomTypes.length; ++j) {\n        const atomIdx = v.nodeShift + j + 1;\n        molfileAtomBlock[v.nodeShift + j] = C.V3K_BEGIN_DATA_LINE + atomIdx + ' ' +\n            monomer.atoms.atomTypes[j] + ' ' +\n            keepPrecision(v.branchPositionShift[0] + monomer.atoms.x[j]) + ' ' +\n            keepPrecision(v.branchPositionShift[1] + v.flipFactor * monomer.atoms.y[j]) +\n            ' ' + monomer.atoms.kwargs[j];\n    }\n}\nfunction fillBondLines(monomer, molfileBondBlock, v) {\n    // construct the lines of V3K molfile bond block\n    for (let j = 0; j < monomer.bonds.atomPairs.length; ++j) {\n        const bondIdx = v.bondShift + j + 1;\n        const firstAtom = monomer.bonds.atomPairs[j][0] + v.nodeShift;\n        const secondAtom = monomer.bonds.atomPairs[j][1] + v.nodeShift;\n        let bondCfg = '';\n        if (monomer.bonds.bondConfiguration.has(j)) {\n            // flip orientation when necessary\n            let orientation = monomer.bonds.bondConfiguration.get(j);\n            if (v.flipFactor < 0)\n                orientation = (orientation === 1) ? 3 : 1;\n            bondCfg = ' CFG=' + orientation;\n        }\n        const kwargs = monomer.bonds.kwargs.has(j) ?\n            ' ' + monomer.bonds.kwargs.get(j) : '';\n        molfileBondBlock[v.bondShift + j] = C.V3K_BEGIN_DATA_LINE + bondIdx + ' ' +\n            monomer.bonds.bondTypes[j] + ' ' +\n            firstAtom + ' ' + secondAtom + bondCfg + kwargs + '\\n';\n    }\n}\nfunction fillChainExtendingBond(monomer, molfileBondBlock, v) {\n    if (v.backboneAttachNode !== 0) {\n        const bondIdx = v.bondShift;\n        const firstAtom = v.backboneAttachNode;\n        const secondAtom = monomer.meta.terminalNodes[0] + v.nodeShift;\n        molfileBondBlock[v.bondShift - 1] = C.V3K_BEGIN_DATA_LINE + bondIdx + ' ' +\n            1 + ' ' + firstAtom + ' ' + secondAtom + '\\n';\n    }\n}\n// todo: remove\nfunction fillBackboneToBranchBond(branchMonomer, molfileBondBlock, v) {\n    const bondIdx = v.bondShift;\n    const firstAtom = v.branchAttachNode;\n    const secondAtom = branchMonomer.meta.terminalNodes[0] + v.nodeShift;\n    molfileBondBlock[bondIdx - 1] = C.V3K_BEGIN_DATA_LINE + bondIdx + ' ' +\n        1 + ' ' + firstAtom + ' ' + secondAtom + '\\n';\n}\n/** Compute the atom/bond counts for the resulting molfile, depending on the\n    * type of polymer (peptide/nucleotide)\n    * @param {string[]}monomerSeq - the sequence of monomers\n    * @param {Map<string, MolGraph>}monomersDict - the dictionary of monomers\n    * @param {ALPHABET}alphabet - the alphabet of the monomers\n    * @param {HELM_POLYMER_TYPE}polymerType - the type of polymer\n    * @return {{atomCount: number, bondCount: number}} - the atom/bond counts*/\nfunction getResultingAtomBondCounts(monomerSeq, monomersDict, alphabet, polymerType) {\n    let atomCount = 0;\n    let bondCount = 0;\n    // sum up all the atoms/nodes provided by the sequence\n    for (const monomerSymbol of monomerSeq) {\n        if (monomerSymbol === '')\n            continue; // Skip for gap/empty monomer in MSA\n        const monomer = monomersDict.get(monomerSymbol);\n        atomCount += monomer.atoms.x.length;\n        bondCount += monomer.bonds.bondTypes.length;\n    }\n    // add extra values depending on the polymer type\n    if (polymerType === \"PEPTIDE\" /* HELM_POLYMER_TYPE.PEPTIDE */) {\n        // add the rightmost/terminating cap group 'OH' (i.e. 'O')\n        atomCount += 1;\n        // add chain-extending bonds (C-NH per each monomer pair and terminal C-OH)\n        bondCount += monomerSeq.length;\n    }\n    else { // nucleotides\n        const sugar = (alphabet === \"DNA\" /* ALPHABET.DNA */) ?\n            monomersDict.get(C.DEOXYRIBOSE) : monomersDict.get(C.RIBOSE);\n        const phosphate = monomersDict.get(C.PHOSPHATE);\n        // add phosphate per each pair of nucleobase symbols\n        atomCount += (monomerSeq.length - 1) * phosphate.atoms.x.length;\n        // add sugar per each nucleobase symbol\n        atomCount += monomerSeq.length * sugar.atoms.x.length;\n        // add the leftmost cap group 'OH' (i.e. 'O')\n        atomCount += 1;\n        // add bonds from phosphate monomers\n        bondCount += (monomerSeq.length - 1) * phosphate.bonds.bondTypes.length;\n        // add bonds from sugar monomers\n        bondCount += monomerSeq.length * sugar.bonds.bondTypes.length;\n        // exclude the first chain-extending bond O-P (absent, no 'leftmost' phosphate)\n        bondCount -= 1;\n        // add chain-extending and branch bonds (O-P, C-O and C-N per each nucleotide)\n        bondCount += monomerSeq.length * 3;\n    }\n    return { atomCount, bondCount };\n}\n/** Keep precision upon floating point operations over atom coordinates\n * @param {number}x - the floating point number\n * @return {number} - the floating point number with the same precision\n*/\nexport function keepPrecision(x) {\n    return Math.round(C.PRECISION_FACTOR * x) / C.PRECISION_FACTOR;\n}\n//# sourceMappingURL=to-atomic-level-utils.js.map","// core fields of HELM library object used in toAtomicLevel function\nexport const HELM_CORE_FIELDS = [\n    \"symbol\" /* HELM_FIELDS.SYMBOL */,\n    \"molfile\" /* HELM_FIELDS.MOLFILE */,\n    \"rgroups\" /* HELM_FIELDS.RGROUPS */,\n    \"name\" /* HELM_FIELDS.NAME */,\n    // HELM_FIELDS.MONOMER_TYPE, // add if terminal monomers for PEPTIDEs to be\n    // supported\n];\nexport const SDF_MONOMER_NAME = 'MonomerName';\n// todo: ideally, keys should be expressed via constants\nexport const jsonSdfMonomerLibDict = {\n    'monomerType': null,\n    'smiles': null,\n    'name': 'MonomerName',\n    'author': null,\n    'molfile': 'molecule',\n    'naturalAnalog': 'MonomerNaturalAnalogCode',\n    'rgroups': 'MonomerCaps',\n    'createDate': null,\n    'id': null,\n    'polymerType': 'MonomerType',\n    'symbol': 'MonomerCode'\n};\nexport const DUMMY_MONOMER = {\n    'monomerType': 'Backbone',\n    'smiles': '',\n    'name': '',\n    'author': 'Datagrok',\n    'molfile': '',\n    'naturalAnalog': '',\n    'rgroups': [],\n    'createDate': null,\n    'id': 0,\n    'polymerType': 'PEPTIDE',\n    'symbol': ''\n};\n// range of hex nubers used in PepSea library to endode monomers\nexport const MONOMER_ENCODE_MIN = 0x100;\nexport const MONOMER_ENCODE_MAX = 0x40A;\nexport const RIBOSE_SYMBOL = 'r';\nexport const DEOXYRIBOSE_SYMBOL = 'd';\nexport const PHOSPHATE_SYMBOL = 'p';\nexport const HELM_WRAPPERS_REGEXP = new RegExp(`[${RIBOSE_SYMBOL}${DEOXYRIBOSE_SYMBOL}]\\\\((\\\\w)\\\\)${PHOSPHATE_SYMBOL}?`, 'g');\n//# sourceMappingURL=const.js.map","import { monomerSeqToMolfile } from './to-atomic-level-utils';\nonmessage = (event) => {\n    const { monomerSequencesArray, monomersDict, alphabet, polymerType, start, end } = event.data;\n    const molfileList = new Array(end - start);\n    const molfileWarningList = new Array(0);\n    for (let rowI = start; rowI < end; ++rowI) {\n        try {\n            const monomerSeq = monomerSequencesArray[rowI];\n            molfileList[rowI - start] = monomerSeqToMolfile(monomerSeq, monomersDict, alphabet, polymerType);\n        }\n        catch (err) {\n            const errMsg = err instanceof Error ? err.message : err.toString();\n            const msg = `Cannot get molfile of row #${rowI}: ${errMsg}.`;\n            molfileWarningList.push(msg);\n        }\n    }\n    postMessage({ molfileList, molfileWarningList });\n};\n//# 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package/dist/895.js

@@ -0,0 +1,3 @@
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1===this.rows||1===this.columns}isSquare(){return this.rows===this.columns}isEmpty(){return 0===this.rows||0===this.columns}isSymmetric(){if(this.isSquare()){for(let t=0;t<this.rows;t++)for(let e=0;e<=t;e++)if(this.get(t,e)!==this.get(e,t))return!1;return!0}return!1}isEchelonForm(){let t=0,e=0,r=-1,s=!0,n=!1;for(;t<this.rows&&s;){for(e=0,n=!1;e<this.columns&&!1===n;)0===this.get(t,e)?e++:1===this.get(t,e)&&e>r?(n=!0,r=e):(s=!1,n=!0);t++}return s}isReducedEchelonForm(){let t=0,e=0,r=-1,s=!0,n=!1;for(;t<this.rows&&s;){for(e=0,n=!1;e<this.columns&&!1===n;)0===this.get(t,e)?e++:1===this.get(t,e)&&e>r?(n=!0,r=e):(s=!1,n=!0);for(let r=e+1;r<this.rows;r++)0!==this.get(t,r)&&(s=!1);t++}return s}echelonForm(){let t=this.clone(),e=0,r=0;for(;e<t.rows&&r<t.columns;){let s=e;for(let n=e;n<t.rows;n++)t.get(n,r)>t.get(s,r)&&(s=n);if(0===t.get(s,r))r++;else{t.swapRows(e,s);let n=t.get(e,r);for(let s=r;s<t.columns;s++)t.set(e,s,t.get(e,s)/n);for(let s=e+1;s<t.rows;s++){let n=t.get(s,r)/t.get(e,r);t.set(s,r,0);for(let o=r+1;o<t.columns;o++)t.set(s,o,t.get(s,o)-t.get(e,o)*n)}e++,r++}}return t}reducedEchelonForm(){let t=this.echelonForm(),e=t.columns,r=t.rows,s=r-1;for(;s>=0;)if(0===t.maxRow(s))s--;else{let n=0,o=!1;for(;n<r&&!1===o;)1===t.get(s,n)?o=!0:n++;for(let r=0;r<s;r++){let o=t.get(r,n);for(let i=n;i<e;i++){let e=t.get(r,i)-o*t.get(s,i);t.set(r,i,e)}}s--}return t}set(){throw new Error("set method is unimplemented")}get(){throw new Error("get method is unimplemented")}repeat(t={}){if("object"!=typeof t)throw new TypeError("options must be an object");const{rows:e=1,columns:r=1}=t;if(!Number.isInteger(e)||e<=0)throw new TypeError("rows must be a positive integer");if(!Number.isInteger(r)||r<=0)throw new TypeError("columns must be a positive integer");let s=new Rt(this.rows*e,this.columns*r);for(let t=0;t<e;t++)for(let e=0;e<r;e++)s.setSubMatrix(this,this.rows*t,this.columns*e);return s}fill(t){for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,t);return this}neg(){return this.mulS(-1)}getRow(t){yt(this,t);let e=[];for(let r=0;r<this.columns;r++)e.push(this.get(t,r));return e}getRowVector(t){return Rt.rowVector(this.getRow(t))}setRow(t,e){yt(this,t),e=Mt(this,e);for(let r=0;r<this.columns;r++)this.set(t,r,e[r]);return this}swapRows(t,e){yt(this,t),yt(this,e);for(let r=0;r<this.columns;r++){let s=this.get(t,r);this.set(t,r,this.get(e,r)),this.set(e,r,s)}return this}getColumn(t){bt(this,t);let e=[];for(let r=0;r<this.rows;r++)e.push(this.get(r,t));return e}getColumnVector(t){return Rt.columnVector(this.getColumn(t))}setColumn(t,e){bt(this,t),e=xt(this,e);for(let r=0;r<this.rows;r++)this.set(r,t,e[r]);return this}swapColumns(t,e){bt(this,t),bt(this,e);for(let r=0;r<this.rows;r++){let s=this.get(r,t);this.set(r,t,this.get(r,e)),this.set(r,e,s)}return this}addRowVector(t){t=Mt(this,t);for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)+t[r]);return this}subRowVector(t){t=Mt(this,t);for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)-t[r]);return this}mulRowVector(t){t=Mt(this,t);for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)*t[r]);return this}divRowVector(t){t=Mt(this,t);for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)/t[r]);return this}addColumnVector(t){t=xt(this,t);for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)+t[e]);return this}subColumnVector(t){t=xt(this,t);for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)-t[e]);return this}mulColumnVector(t){t=xt(this,t);for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)*t[e]);return this}divColumnVector(t){t=xt(this,t);for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)/t[e]);return this}mulRow(t,e){yt(this,t);for(let r=0;r<this.columns;r++)this.set(t,r,this.get(t,r)*e);return this}mulColumn(t,e){bt(this,t);for(let r=0;r<this.rows;r++)this.set(r,t,this.get(r,t)*e);return this}max(t){if(this.isEmpty())return NaN;switch(t){case"row":{const t=new Array(this.rows).fill(Number.NEGATIVE_INFINITY);for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.get(e,r)>t[e]&&(t[e]=this.get(e,r));return t}case"column":{const t=new Array(this.columns).fill(Number.NEGATIVE_INFINITY);for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.get(e,r)>t[r]&&(t[r]=this.get(e,r));return t}case void 0:{let t=this.get(0,0);for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.get(e,r)>t&&(t=this.get(e,r));return t}default:throw new Error(`invalid option: ${t}`)}}maxIndex(){kt(this);let t=this.get(0,0),e=[0,0];for(let r=0;r<this.rows;r++)for(let s=0;s<this.columns;s++)this.get(r,s)>t&&(t=this.get(r,s),e[0]=r,e[1]=s);return e}min(t){if(this.isEmpty())return NaN;switch(t){case"row":{const t=new Array(this.rows).fill(Number.POSITIVE_INFINITY);for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.get(e,r)<t[e]&&(t[e]=this.get(e,r));return t}case"column":{const t=new Array(this.columns).fill(Number.POSITIVE_INFINITY);for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.get(e,r)<t[r]&&(t[r]=this.get(e,r));return t}case void 0:{let t=this.get(0,0);for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.get(e,r)<t&&(t=this.get(e,r));return t}default:throw new Error(`invalid option: ${t}`)}}minIndex(){kt(this);let t=this.get(0,0),e=[0,0];for(let r=0;r<this.rows;r++)for(let s=0;s<this.columns;s++)this.get(r,s)<t&&(t=this.get(r,s),e[0]=r,e[1]=s);return e}maxRow(t){if(yt(this,t),this.isEmpty())return NaN;let e=this.get(t,0);for(let r=1;r<this.columns;r++)this.get(t,r)>e&&(e=this.get(t,r));return e}maxRowIndex(t){yt(this,t),kt(this);let e=this.get(t,0),r=[t,0];for(let s=1;s<this.columns;s++)this.get(t,s)>e&&(e=this.get(t,s),r[1]=s);return r}minRow(t){if(yt(this,t),this.isEmpty())return NaN;let e=this.get(t,0);for(let r=1;r<this.columns;r++)this.get(t,r)<e&&(e=this.get(t,r));return e}minRowIndex(t){yt(this,t),kt(this);let e=this.get(t,0),r=[t,0];for(let s=1;s<this.columns;s++)this.get(t,s)<e&&(e=this.get(t,s),r[1]=s);return r}maxColumn(t){if(bt(this,t),this.isEmpty())return NaN;let e=this.get(0,t);for(let r=1;r<this.rows;r++)this.get(r,t)>e&&(e=this.get(r,t));return e}maxColumnIndex(t){bt(this,t),kt(this);let e=this.get(0,t),r=[0,t];for(let s=1;s<this.rows;s++)this.get(s,t)>e&&(e=this.get(s,t),r[0]=s);return r}minColumn(t){if(bt(this,t),this.isEmpty())return NaN;let e=this.get(0,t);for(let r=1;r<this.rows;r++)this.get(r,t)<e&&(e=this.get(r,t));return e}minColumnIndex(t){bt(this,t),kt(this);let e=this.get(0,t),r=[0,t];for(let s=1;s<this.rows;s++)this.get(s,t)<e&&(e=this.get(s,t),r[0]=s);return r}diag(){let t=Math.min(this.rows,this.columns),e=[];for(let r=0;r<t;r++)e.push(this.get(r,r));return e}norm(t="frobenius"){let e=0;if("max"===t)return this.max();if("frobenius"===t){for(let t=0;t<this.rows;t++)for(let r=0;r<this.columns;r++)e+=this.get(t,r)*this.get(t,r);return Math.sqrt(e)}throw new RangeError(`unknown norm type: ${t}`)}cumulativeSum(){let t=0;for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)t+=this.get(e,r),this.set(e,r,t);return this}dot(t){Nt.isMatrix(t)&&(t=t.to1DArray());let e=this.to1DArray();if(e.length!==t.length)throw new RangeError("vectors do not have the same size");let r=0;for(let s=0;s<e.length;s++)r+=e[s]*t[s];return r}mmul(t){t=Rt.checkMatrix(t);let e=this.rows,r=this.columns,s=t.columns,n=new Rt(e,s),o=new Float64Array(r);for(let i=0;i<s;i++){for(let e=0;e<r;e++)o[e]=t.get(e,i);for(let t=0;t<e;t++){let e=0;for(let s=0;s<r;s++)e+=this.get(t,s)*o[s];n.set(t,i,e)}}return n}strassen2x2(t){t=Rt.checkMatrix(t);let e=new Rt(2,2);const r=this.get(0,0),s=t.get(0,0),n=this.get(0,1),o=t.get(0,1),i=this.get(1,0),h=t.get(1,0),a=this.get(1,1),l=t.get(1,1),u=(r+a)*(s+l),c=(i+a)*s,f=r*(o-l),g=a*(h-s),m=(r+n)*l,p=u+g-m+(n-a)*(h+l),w=f+m,d=c+g,y=u-c+f+(i-r)*(s+o);return e.set(0,0,p),e.set(0,1,w),e.set(1,0,d),e.set(1,1,y),e}strassen3x3(t){t=Rt.checkMatrix(t);let e=new Rt(3,3);const r=this.get(0,0),s=this.get(0,1),n=this.get(0,2),o=this.get(1,0),i=this.get(1,1),h=this.get(1,2),a=this.get(2,0),l=this.get(2,1),u=this.get(2,2),c=t.get(0,0),f=t.get(0,1),g=t.get(0,2),m=t.get(1,0),p=t.get(1,1),w=t.get(1,2),d=t.get(2,0),y=t.get(2,1),b=t.get(2,2),M=(r-o)*(-f+p),x=(-r+o+i)*(c-f+p),v=(o+i)*(-c+f),E=r*c,S=(-r+a+l)*(c-g+w),k=(-r+a)*(g-w),N=(a+l)*(-c+g),A=(-n+l+u)*(p+d-y),R=(n-u)*(p-y),F=n*d,C=(l+u)*(-d+y),z=(-n+i+h)*(w+d-b),I=(n-h)*(w-b),T=(i+h)*(-d+b),D=E+F+s*m,V=(r+s+n-o-i-l-u)*p+x+v+E+A+F+C,O=E+S+N+(r+s+n-i-h-a-l)*w+F+z+T,q=M+i*(-c+f+m-p-w-d+b)+x+E+F+z+I,P=M+x+v+E+h*y,j=F+z+I+T+o*g,L=E+S+k+l*(-c+g+m-p-w-d+y)+A+R+F,_=A+R+F+C+a*f,$=E+S+k+N+u*b;return e.set(0,0,D),e.set(0,1,V),e.set(0,2,O),e.set(1,0,q),e.set(1,1,P),e.set(1,2,j),e.set(2,0,L),e.set(2,1,_),e.set(2,2,$),e}mmulStrassen(t){t=Rt.checkMatrix(t);let e=this.clone(),r=e.rows,s=e.columns,n=t.rows,o=t.columns;function i(t,e,r){let s=t.rows,n=t.columns;if(s===e&&n===r)return t;{let s=Nt.zeros(e,r);return s=s.setSubMatrix(t,0,0),s}}s!==n&&console.warn(`Multiplying ${r} x ${s} and ${n} x ${o} matrix: dimensions do not match.`);let h=Math.max(r,n),a=Math.max(s,o);return e=i(e,h,a),function t(e,r,s,n){if(s<=512||n<=512)return e.mmul(r);s%2==1&&n%2==1?(e=i(e,s+1,n+1),r=i(r,s+1,n+1)):s%2==1?(e=i(e,s+1,n),r=i(r,s+1,n)):n%2==1&&(e=i(e,s,n+1),r=i(r,s,n+1));let o=parseInt(e.rows/2,10),h=parseInt(e.columns/2,10),a=e.subMatrix(0,o-1,0,h-1),l=r.subMatrix(0,o-1,0,h-1),u=e.subMatrix(0,o-1,h,e.columns-1),c=r.subMatrix(0,o-1,h,r.columns-1),f=e.subMatrix(o,e.rows-1,0,h-1),g=r.subMatrix(o,r.rows-1,0,h-1),m=e.subMatrix(o,e.rows-1,h,e.columns-1),p=r.subMatrix(o,r.rows-1,h,r.columns-1),w=t(Nt.add(a,m),Nt.add(l,p),o,h),d=t(Nt.add(f,m),l,o,h),y=t(a,Nt.sub(c,p),o,h),b=t(m,Nt.sub(g,l),o,h),M=t(Nt.add(a,u),p,o,h),x=t(Nt.sub(f,a),Nt.add(l,c),o,h),v=t(Nt.sub(u,m),Nt.add(g,p),o,h),E=Nt.add(w,b);E.sub(M),E.add(v);let S=Nt.add(y,M),k=Nt.add(d,b),N=Nt.sub(w,d);N.add(y),N.add(x);let A=Nt.zeros(2*E.rows,2*E.columns);return A=A.setSubMatrix(E,0,0),A=A.setSubMatrix(S,E.rows,0),A=A.setSubMatrix(k,0,E.columns),A=A.setSubMatrix(N,E.rows,E.columns),A.subMatrix(0,s-1,0,n-1)}(e,t=i(t,h,a),h,a)}scaleRows(t={}){if("object"!=typeof t)throw new TypeError("options must be an object");const{min:e=0,max:r=1}=t;if(!Number.isFinite(e))throw new TypeError("min must be a number");if(!Number.isFinite(r))throw new TypeError("max must be a number");if(e>=r)throw new RangeError("min must be smaller than max");let s=new Rt(this.rows,this.columns);for(let t=0;t<this.rows;t++){const n=this.getRow(t);n.length>0&&ft(n,{min:e,max:r,output:n}),s.setRow(t,n)}return s}scaleColumns(t={}){if("object"!=typeof t)throw new TypeError("options must be an object");const{min:e=0,max:r=1}=t;if(!Number.isFinite(e))throw new TypeError("min must be a number");if(!Number.isFinite(r))throw new TypeError("max must be a number");if(e>=r)throw new RangeError("min must be smaller than max");let s=new Rt(this.rows,this.columns);for(let t=0;t<this.columns;t++){const n=this.getColumn(t);n.length&&ft(n,{min:e,max:r,output:n}),s.setColumn(t,n)}return s}flipRows(){const t=Math.ceil(this.columns/2);for(let e=0;e<this.rows;e++)for(let r=0;r<t;r++){let t=this.get(e,r),s=this.get(e,this.columns-1-r);this.set(e,r,s),this.set(e,this.columns-1-r,t)}return this}flipColumns(){const t=Math.ceil(this.rows/2);for(let e=0;e<this.columns;e++)for(let r=0;r<t;r++){let t=this.get(r,e),s=this.get(this.rows-1-r,e);this.set(r,e,s),this.set(this.rows-1-r,e,t)}return this}kroneckerProduct(t){t=Rt.checkMatrix(t);let e=this.rows,r=this.columns,s=t.rows,n=t.columns,o=new Rt(e*s,r*n);for(let i=0;i<e;i++)for(let e=0;e<r;e++)for(let r=0;r<s;r++)for(let h=0;h<n;h++)o.set(s*i+r,n*e+h,this.get(i,e)*t.get(r,h));return o}kroneckerSum(t){if(t=Rt.checkMatrix(t),!this.isSquare()||!t.isSquare())throw new Error("Kronecker Sum needs two Square Matrices");let e=this.rows,r=t.rows,s=this.kroneckerProduct(Rt.eye(r,r)),n=Rt.eye(e,e).kroneckerProduct(t);return s.add(n)}transpose(){let t=new Rt(this.columns,this.rows);for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)t.set(r,e,this.get(e,r));return t}sortRows(t=At){for(let e=0;e<this.rows;e++)this.setRow(e,this.getRow(e).sort(t));return this}sortColumns(t=At){for(let e=0;e<this.columns;e++)this.setColumn(e,this.getColumn(e).sort(t));return this}subMatrix(t,e,r,s){vt(this,t,e,r,s);let n=new Rt(e-t+1,s-r+1);for(let o=t;o<=e;o++)for(let e=r;e<=s;e++)n.set(o-t,e-r,this.get(o,e));return n}subMatrixRow(t,e,r){if(void 0===e&&(e=0),void 0===r&&(r=this.columns-1),e>r||e<0||e>=this.columns||r<0||r>=this.columns)throw new RangeError("Argument out of range");let s=new Rt(t.length,r-e+1);for(let n=0;n<t.length;n++)for(let o=e;o<=r;o++){if(t[n]<0||t[n]>=this.rows)throw new RangeError(`Row index out of range: ${t[n]}`);s.set(n,o-e,this.get(t[n],o))}return s}subMatrixColumn(t,e,r){if(void 0===e&&(e=0),void 0===r&&(r=this.rows-1),e>r||e<0||e>=this.rows||r<0||r>=this.rows)throw new RangeError("Argument out of range");let s=new Rt(r-e+1,t.length);for(let n=0;n<t.length;n++)for(let o=e;o<=r;o++){if(t[n]<0||t[n]>=this.columns)throw new RangeError(`Column index out of range: ${t[n]}`);s.set(o-e,n,this.get(o,t[n]))}return s}setSubMatrix(t,e,r){if((t=Rt.checkMatrix(t)).isEmpty())return this;vt(this,e,e+t.rows-1,r,r+t.columns-1);for(let s=0;s<t.rows;s++)for(let n=0;n<t.columns;n++)this.set(e+s,r+n,t.get(s,n));return this}selection(t,e){!function(t,e){if(!ht(e))throw new TypeError("row indices must be an array");for(let r=0;r<e.length;r++)if(e[r]<0||e[r]>=t.rows)throw new RangeError("row indices are out of range")}(this,t),function(t,e){if(!ht(e))throw new TypeError("column indices must be an array");for(let r=0;r<e.length;r++)if(e[r]<0||e[r]>=t.columns)throw new RangeError("column indices are out of range")}(this,e);let r=new Rt(t.length,e.length);for(let s=0;s<t.length;s++){let n=t[s];for(let t=0;t<e.length;t++){let o=e[t];r.set(s,t,this.get(n,o))}}return r}trace(){let t=Math.min(this.rows,this.columns),e=0;for(let r=0;r<t;r++)e+=this.get(r,r);return e}clone(){let t=new Rt(this.rows,this.columns);for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)t.set(e,r,this.get(e,r));return t}sum(t){switch(t){case"row":return function(t){let e=Et(t.rows);for(let r=0;r<t.rows;++r)for(let s=0;s<t.columns;++s)e[r]+=t.get(r,s);return e}(this);case"column":return function(t){let e=Et(t.columns);for(let r=0;r<t.rows;++r)for(let s=0;s<t.columns;++s)e[s]+=t.get(r,s);return e}(this);case void 0:return function(t){let e=0;for(let r=0;r<t.rows;r++)for(let s=0;s<t.columns;s++)e+=t.get(r,s);return e}(this);default:throw new Error(`invalid option: ${t}`)}}product(t){switch(t){case"row":return function(t){let e=Et(t.rows,1);for(let r=0;r<t.rows;++r)for(let s=0;s<t.columns;++s)e[r]*=t.get(r,s);return e}(this);case"column":return function(t){let e=Et(t.columns,1);for(let r=0;r<t.rows;++r)for(let s=0;s<t.columns;++s)e[s]*=t.get(r,s);return e}(this);case void 0:return function(t){let e=1;for(let r=0;r<t.rows;r++)for(let s=0;s<t.columns;s++)e*=t.get(r,s);return e}(this);default:throw new Error(`invalid option: ${t}`)}}mean(t){const e=this.sum(t);switch(t){case"row":for(let t=0;t<this.rows;t++)e[t]/=this.columns;return e;case"column":for(let t=0;t<this.columns;t++)e[t]/=this.rows;return e;case void 0:return e/this.size;default:throw new Error(`invalid option: ${t}`)}}variance(t,e={}){if("object"==typeof t&&(e=t,t=void 0),"object"!=typeof e)throw new TypeError("options must be an object");const{unbiased:r=!0,mean:s=this.mean(t)}=e;if("boolean"!=typeof r)throw new TypeError("unbiased must be a boolean");switch(t){case"row":if(!ht(s))throw new TypeError("mean must be an array");return function(t,e,r){const s=t.rows,n=t.columns,o=[];for(let i=0;i<s;i++){let s=0,h=0,a=0;for(let e=0;e<n;e++)a=t.get(i,e)-r[i],s+=a,h+=a*a;e?o.push((h-s*s/n)/(n-1)):o.push((h-s*s/n)/n)}return o}(this,r,s);case"column":if(!ht(s))throw new TypeError("mean must be an array");return function(t,e,r){const s=t.rows,n=t.columns,o=[];for(let i=0;i<n;i++){let n=0,h=0,a=0;for(let e=0;e<s;e++)a=t.get(e,i)-r[i],n+=a,h+=a*a;e?o.push((h-n*n/s)/(s-1)):o.push((h-n*n/s)/s)}return o}(this,r,s);case void 0:if("number"!=typeof s)throw new TypeError("mean must be a number");return function(t,e,r){const s=t.rows,n=t.columns,o=s*n;let i=0,h=0,a=0;for(let e=0;e<s;e++)for(let s=0;s<n;s++)a=t.get(e,s)-r,i+=a,h+=a*a;return e?(h-i*i/o)/(o-1):(h-i*i/o)/o}(this,r,s);default:throw new Error(`invalid option: ${t}`)}}standardDeviation(t,e){"object"==typeof t&&(e=t,t=void 0);const r=this.variance(t,e);if(void 0===t)return Math.sqrt(r);for(let t=0;t<r.length;t++)r[t]=Math.sqrt(r[t]);return r}center(t,e={}){if("object"==typeof t&&(e=t,t=void 0),"object"!=typeof e)throw new TypeError("options must be an object");const{center:r=this.mean(t)}=e;switch(t){case"row":if(!ht(r))throw new TypeError("center must be an array");return function(t,e){for(let r=0;r<t.rows;r++)for(let s=0;s<t.columns;s++)t.set(r,s,t.get(r,s)-e[r])}(this,r),this;case"column":if(!ht(r))throw new TypeError("center must be an array");return function(t,e){for(let r=0;r<t.rows;r++)for(let s=0;s<t.columns;s++)t.set(r,s,t.get(r,s)-e[s])}(this,r),this;case void 0:if("number"!=typeof r)throw new TypeError("center must be a number");return function(t,e){for(let r=0;r<t.rows;r++)for(let s=0;s<t.columns;s++)t.set(r,s,t.get(r,s)-e)}(this,r),this;default:throw new Error(`invalid option: ${t}`)}}scale(t,e={}){if("object"==typeof t&&(e=t,t=void 0),"object"!=typeof e)throw new TypeError("options must be an object");let r=e.scale;switch(t){case"row":if(void 0===r)r=function(t){const e=[];for(let r=0;r<t.rows;r++){let s=0;for(let e=0;e<t.columns;e++)s+=Math.pow(t.get(r,e),2)/(t.columns-1);e.push(Math.sqrt(s))}return e}(this);else if(!ht(r))throw new TypeError("scale must be an array");return function(t,e){for(let r=0;r<t.rows;r++)for(let s=0;s<t.columns;s++)t.set(r,s,t.get(r,s)/e[r])}(this,r),this;case"column":if(void 0===r)r=function(t){const e=[];for(let r=0;r<t.columns;r++){let s=0;for(let e=0;e<t.rows;e++)s+=Math.pow(t.get(e,r),2)/(t.rows-1);e.push(Math.sqrt(s))}return e}(this);else if(!ht(r))throw new TypeError("scale must be an array");return function(t,e){for(let r=0;r<t.rows;r++)for(let s=0;s<t.columns;s++)t.set(r,s,t.get(r,s)/e[s])}(this,r),this;case void 0:if(void 0===r)r=function(t){const e=t.size-1;let r=0;for(let s=0;s<t.columns;s++)for(let n=0;n<t.rows;n++)r+=Math.pow(t.get(n,s),2)/e;return Math.sqrt(r)}(this);else if("number"!=typeof r)throw new TypeError("scale must be a number");return function(t,e){for(let r=0;r<t.rows;r++)for(let s=0;s<t.columns;s++)t.set(r,s,t.get(r,s)/e)}(this,r),this;default:throw new Error(`invalid option: ${t}`)}}toString(t){return pt(this,t)}}function At(t,e){return t-e}Nt.prototype.klass="Matrix","undefined"!=typeof Symbol&&(Nt.prototype[Symbol.for("nodejs.util.inspect.custom")]=function(){return pt(this)}),Nt.random=Nt.rand,Nt.randomInt=Nt.randInt,Nt.diagonal=Nt.diag,Nt.prototype.diagonal=Nt.prototype.diag,Nt.identity=Nt.eye,Nt.prototype.negate=Nt.prototype.neg,Nt.prototype.tensorProduct=Nt.prototype.kroneckerProduct;class Rt extends Nt{constructor(t,e){if(super(),Rt.isMatrix(t))return t.clone();if(Number.isInteger(t)&&t>=0){if(this.data=[],!(Number.isInteger(e)&&e>=0))throw new TypeError("nColumns must be a positive integer");for(let r=0;r<t;r++)this.data.push(new Float64Array(e))}else{if(!ht(t))throw new TypeError("First argument must be a positive number or an array");{const r=t;if("number"!=typeof(e=(t=r.length)?r[0].length:0))throw new TypeError("Data must be a 2D array with at least one element");this.data=[];for(let s=0;s<t;s++){if(r[s].length!==e)throw new RangeError("Inconsistent array dimensions");if(!r[s].every((t=>"number"==typeof t)))throw new TypeError("Input data contains non-numeric values");this.data.push(Float64Array.from(r[s]))}}}this.rows=t,this.columns=e}set(t,e,r){return this.data[t][e]=r,this}get(t,e){return this.data[t][e]}removeRow(t){return yt(this,t),this.data.splice(t,1),this.rows-=1,this}addRow(t,e){return void 0===e&&(e=t,t=this.rows),yt(this,t,!0),e=Float64Array.from(Mt(this,e)),this.data.splice(t,0,e),this.rows+=1,this}removeColumn(t){bt(this,t);for(let e=0;e<this.rows;e++){const r=new Float64Array(this.columns-1);for(let s=0;s<t;s++)r[s]=this.data[e][s];for(let s=t+1;s<this.columns;s++)r[s-1]=this.data[e][s];this.data[e]=r}return this.columns-=1,this}addColumn(t,e){void 0===e&&(e=t,t=this.columns),bt(this,t,!0),e=xt(this,e);for(let r=0;r<this.rows;r++){const s=new Float64Array(this.columns+1);let n=0;for(;n<t;n++)s[n]=this.data[r][n];for(s[n++]=e[r];n<this.columns+1;n++)s[n]=this.data[r][n-1];this.data[r]=s}return this.columns+=1,this}}!function(t,e){t.prototype.add=function(t){return"number"==typeof t?this.addS(t):this.addM(t)},t.prototype.addS=function(t){for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)+t);return this},t.prototype.addM=function(t){if(t=e.checkMatrix(t),this.rows!==t.rows||this.columns!==t.columns)throw new RangeError("Matrices dimensions must be equal");for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)+t.get(e,r));return this},t.add=function(t,r){return new e(t).add(r)},t.prototype.sub=function(t){return"number"==typeof t?this.subS(t):this.subM(t)},t.prototype.subS=function(t){for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)-t);return this},t.prototype.subM=function(t){if(t=e.checkMatrix(t),this.rows!==t.rows||this.columns!==t.columns)throw new RangeError("Matrices dimensions must be equal");for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)-t.get(e,r));return this},t.sub=function(t,r){return new e(t).sub(r)},t.prototype.subtract=t.prototype.sub,t.prototype.subtractS=t.prototype.subS,t.prototype.subtractM=t.prototype.subM,t.subtract=t.sub,t.prototype.mul=function(t){return"number"==typeof t?this.mulS(t):this.mulM(t)},t.prototype.mulS=function(t){for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)*t);return this},t.prototype.mulM=function(t){if(t=e.checkMatrix(t),this.rows!==t.rows||this.columns!==t.columns)throw new RangeError("Matrices dimensions must be equal");for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)*t.get(e,r));return this},t.mul=function(t,r){return new e(t).mul(r)},t.prototype.multiply=t.prototype.mul,t.prototype.multiplyS=t.prototype.mulS,t.prototype.multiplyM=t.prototype.mulM,t.multiply=t.mul,t.prototype.div=function(t){return"number"==typeof t?this.divS(t):this.divM(t)},t.prototype.divS=function(t){for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)/t);return this},t.prototype.divM=function(t){if(t=e.checkMatrix(t),this.rows!==t.rows||this.columns!==t.columns)throw new RangeError("Matrices dimensions must be equal");for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)/t.get(e,r));return this},t.div=function(t,r){return new e(t).div(r)},t.prototype.divide=t.prototype.div,t.prototype.divideS=t.prototype.divS,t.prototype.divideM=t.prototype.divM,t.divide=t.div,t.prototype.mod=function(t){return"number"==typeof t?this.modS(t):this.modM(t)},t.prototype.modS=function(t){for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)%t);return this},t.prototype.modM=function(t){if(t=e.checkMatrix(t),this.rows!==t.rows||this.columns!==t.columns)throw new RangeError("Matrices dimensions must be equal");for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)%t.get(e,r));return this},t.mod=function(t,r){return new e(t).mod(r)},t.prototype.modulus=t.prototype.mod,t.prototype.modulusS=t.prototype.modS,t.prototype.modulusM=t.prototype.modM,t.modulus=t.mod,t.prototype.and=function(t){return"number"==typeof t?this.andS(t):this.andM(t)},t.prototype.andS=function(t){for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)&t);return this},t.prototype.andM=function(t){if(t=e.checkMatrix(t),this.rows!==t.rows||this.columns!==t.columns)throw new RangeError("Matrices dimensions must be equal");for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)&t.get(e,r));return this},t.and=function(t,r){return new e(t).and(r)},t.prototype.or=function(t){return"number"==typeof t?this.orS(t):this.orM(t)},t.prototype.orS=function(t){for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)|t);return this},t.prototype.orM=function(t){if(t=e.checkMatrix(t),this.rows!==t.rows||this.columns!==t.columns)throw new RangeError("Matrices dimensions must be equal");for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)|t.get(e,r));return this},t.or=function(t,r){return new e(t).or(r)},t.prototype.xor=function(t){return"number"==typeof t?this.xorS(t):this.xorM(t)},t.prototype.xorS=function(t){for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)^t);return this},t.prototype.xorM=function(t){if(t=e.checkMatrix(t),this.rows!==t.rows||this.columns!==t.columns)throw new RangeError("Matrices dimensions must be equal");for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)^t.get(e,r));return this},t.xor=function(t,r){return new e(t).xor(r)},t.prototype.leftShift=function(t){return"number"==typeof t?this.leftShiftS(t):this.leftShiftM(t)},t.prototype.leftShiftS=function(t){for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)<<t);return this},t.prototype.leftShiftM=function(t){if(t=e.checkMatrix(t),this.rows!==t.rows||this.columns!==t.columns)throw new RangeError("Matrices dimensions must be equal");for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)<<t.get(e,r));return this},t.leftShift=function(t,r){return new e(t).leftShift(r)},t.prototype.signPropagatingRightShift=function(t){return"number"==typeof t?this.signPropagatingRightShiftS(t):this.signPropagatingRightShiftM(t)},t.prototype.signPropagatingRightShiftS=function(t){for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)>>t);return this},t.prototype.signPropagatingRightShiftM=function(t){if(t=e.checkMatrix(t),this.rows!==t.rows||this.columns!==t.columns)throw new RangeError("Matrices dimensions must be equal");for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)>>t.get(e,r));return this},t.signPropagatingRightShift=function(t,r){return new e(t).signPropagatingRightShift(r)},t.prototype.rightShift=function(t){return"number"==typeof t?this.rightShiftS(t):this.rightShiftM(t)},t.prototype.rightShiftS=function(t){for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)>>>t);return this},t.prototype.rightShiftM=function(t){if(t=e.checkMatrix(t),this.rows!==t.rows||this.columns!==t.columns)throw new RangeError("Matrices dimensions must be equal");for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,this.get(e,r)>>>t.get(e,r));return this},t.rightShift=function(t,r){return new e(t).rightShift(r)},t.prototype.zeroFillRightShift=t.prototype.rightShift,t.prototype.zeroFillRightShiftS=t.prototype.rightShiftS,t.prototype.zeroFillRightShiftM=t.prototype.rightShiftM,t.zeroFillRightShift=t.rightShift,t.prototype.not=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,~this.get(t,e));return this},t.not=function(t){return new e(t).not()},t.prototype.abs=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.abs(this.get(t,e)));return this},t.abs=function(t){return new e(t).abs()},t.prototype.acos=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.acos(this.get(t,e)));return this},t.acos=function(t){return new e(t).acos()},t.prototype.acosh=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.acosh(this.get(t,e)));return this},t.acosh=function(t){return new e(t).acosh()},t.prototype.asin=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.asin(this.get(t,e)));return this},t.asin=function(t){return new e(t).asin()},t.prototype.asinh=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.asinh(this.get(t,e)));return this},t.asinh=function(t){return new e(t).asinh()},t.prototype.atan=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.atan(this.get(t,e)));return this},t.atan=function(t){return new e(t).atan()},t.prototype.atanh=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.atanh(this.get(t,e)));return this},t.atanh=function(t){return new e(t).atanh()},t.prototype.cbrt=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.cbrt(this.get(t,e)));return this},t.cbrt=function(t){return new e(t).cbrt()},t.prototype.ceil=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.ceil(this.get(t,e)));return this},t.ceil=function(t){return new e(t).ceil()},t.prototype.clz32=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.clz32(this.get(t,e)));return this},t.clz32=function(t){return new e(t).clz32()},t.prototype.cos=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.cos(this.get(t,e)));return this},t.cos=function(t){return new e(t).cos()},t.prototype.cosh=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.cosh(this.get(t,e)));return this},t.cosh=function(t){return new e(t).cosh()},t.prototype.exp=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.exp(this.get(t,e)));return this},t.exp=function(t){return new e(t).exp()},t.prototype.expm1=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.expm1(this.get(t,e)));return this},t.expm1=function(t){return new e(t).expm1()},t.prototype.floor=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.floor(this.get(t,e)));return this},t.floor=function(t){return new e(t).floor()},t.prototype.fround=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.fround(this.get(t,e)));return this},t.fround=function(t){return new e(t).fround()},t.prototype.log=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.log(this.get(t,e)));return this},t.log=function(t){return new e(t).log()},t.prototype.log1p=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.log1p(this.get(t,e)));return this},t.log1p=function(t){return new e(t).log1p()},t.prototype.log10=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.log10(this.get(t,e)));return this},t.log10=function(t){return new e(t).log10()},t.prototype.log2=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.log2(this.get(t,e)));return this},t.log2=function(t){return new e(t).log2()},t.prototype.round=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.round(this.get(t,e)));return this},t.round=function(t){return new e(t).round()},t.prototype.sign=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.sign(this.get(t,e)));return this},t.sign=function(t){return new e(t).sign()},t.prototype.sin=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.sin(this.get(t,e)));return this},t.sin=function(t){return new e(t).sin()},t.prototype.sinh=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.sinh(this.get(t,e)));return this},t.sinh=function(t){return new e(t).sinh()},t.prototype.sqrt=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.sqrt(this.get(t,e)));return this},t.sqrt=function(t){return new e(t).sqrt()},t.prototype.tan=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.tan(this.get(t,e)));return this},t.tan=function(t){return new e(t).tan()},t.prototype.tanh=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.tanh(this.get(t,e)));return this},t.tanh=function(t){return new e(t).tanh()},t.prototype.trunc=function(){for(let t=0;t<this.rows;t++)for(let e=0;e<this.columns;e++)this.set(t,e,Math.trunc(this.get(t,e)));return this},t.trunc=function(t){return new e(t).trunc()},t.pow=function(t,r){return new e(t).pow(r)},t.prototype.pow=function(t){return"number"==typeof t?this.powS(t):this.powM(t)},t.prototype.powS=function(t){for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,Math.pow(this.get(e,r),t));return this},t.prototype.powM=function(t){if(t=e.checkMatrix(t),this.rows!==t.rows||this.columns!==t.columns)throw new RangeError("Matrices dimensions must be equal");for(let e=0;e<this.rows;e++)for(let r=0;r<this.columns;r++)this.set(e,r,Math.pow(this.get(e,r),t.get(e,r)));return this}}(Nt,Rt);class Ft extends Nt{constructor(t){super(),this.data=t,this.rows=t.length,this.columns=t[0].length}set(t,e,r){return this.data[t][e]=r,this}get(t,e){return this.data[t][e]}}class Ct{constructor(t){let e,r,s,n,o,i,h,a,l,u=(t=Ft.checkMatrix(t)).clone(),c=u.rows,f=u.columns,g=new Float64Array(c),m=1;for(e=0;e<c;e++)g[e]=e;for(a=new Float64Array(c),r=0;r<f;r++){for(e=0;e<c;e++)a[e]=u.get(e,r);for(e=0;e<c;e++){for(l=Math.min(e,r),o=0,s=0;s<l;s++)o+=u.get(e,s)*a[s];a[e]-=o,u.set(e,r,a[e])}for(n=r,e=r+1;e<c;e++)Math.abs(a[e])>Math.abs(a[n])&&(n=e);if(n!==r){for(s=0;s<f;s++)i=u.get(n,s),u.set(n,s,u.get(r,s)),u.set(r,s,i);h=g[n],g[n]=g[r],g[r]=h,m=-m}if(r<c&&0!==u.get(r,r))for(e=r+1;e<c;e++)u.set(e,r,u.get(e,r)/u.get(r,r))}this.LU=u,this.pivotVector=g,this.pivotSign=m}isSingular(){let t=this.LU,e=t.columns;for(let r=0;r<e;r++)if(0===t.get(r,r))return!0;return!1}solve(t){t=Rt.checkMatrix(t);let e=this.LU;if(e.rows!==t.rows)throw new Error("Invalid matrix dimensions");if(this.isSingular())throw new Error("LU matrix is singular");let r,s,n,o=t.columns,i=t.subMatrixRow(this.pivotVector,0,o-1),h=e.columns;for(n=0;n<h;n++)for(r=n+1;r<h;r++)for(s=0;s<o;s++)i.set(r,s,i.get(r,s)-i.get(n,s)*e.get(r,n));for(n=h-1;n>=0;n--){for(s=0;s<o;s++)i.set(n,s,i.get(n,s)/e.get(n,n));for(r=0;r<n;r++)for(s=0;s<o;s++)i.set(r,s,i.get(r,s)-i.get(n,s)*e.get(r,n))}return i}get determinant(){let t=this.LU;if(!t.isSquare())throw new Error("Matrix must be square");let e=this.pivotSign,r=t.columns;for(let s=0;s<r;s++)e*=t.get(s,s);return e}get lowerTriangularMatrix(){let t=this.LU,e=t.rows,r=t.columns,s=new Rt(e,r);for(let n=0;n<e;n++)for(let e=0;e<r;e++)n>e?s.set(n,e,t.get(n,e)):n===e?s.set(n,e,1):s.set(n,e,0);return s}get upperTriangularMatrix(){let t=this.LU,e=t.rows,r=t.columns,s=new Rt(e,r);for(let n=0;n<e;n++)for(let e=0;e<r;e++)n<=e?s.set(n,e,t.get(n,e)):s.set(n,e,0);return s}get pivotPermutationVector(){return Array.from(this.pivotVector)}}function zt(t,e){let r=0;return Math.abs(t)>Math.abs(e)?(r=e/t,Math.abs(t)*Math.sqrt(1+r*r)):0!==e?(r=t/e,Math.abs(e)*Math.sqrt(1+r*r)):0}class It{constructor(t){let e,r,s,n,o=(t=Ft.checkMatrix(t)).clone(),i=t.rows,h=t.columns,a=new Float64Array(h);for(s=0;s<h;s++){let t=0;for(e=s;e<i;e++)t=zt(t,o.get(e,s));if(0!==t){for(o.get(s,s)<0&&(t=-t),e=s;e<i;e++)o.set(e,s,o.get(e,s)/t);for(o.set(s,s,o.get(s,s)+1),r=s+1;r<h;r++){for(n=0,e=s;e<i;e++)n+=o.get(e,s)*o.get(e,r);for(n=-n/o.get(s,s),e=s;e<i;e++)o.set(e,r,o.get(e,r)+n*o.get(e,s))}}a[s]=-t}this.QR=o,this.Rdiag=a}solve(t){t=Rt.checkMatrix(t);let e=this.QR,r=e.rows;if(t.rows!==r)throw new Error("Matrix row dimensions must agree");if(!this.isFullRank())throw new Error("Matrix is rank deficient");let s,n,o,i,h=t.columns,a=t.clone(),l=e.columns;for(o=0;o<l;o++)for(n=0;n<h;n++){for(i=0,s=o;s<r;s++)i+=e.get(s,o)*a.get(s,n);for(i=-i/e.get(o,o),s=o;s<r;s++)a.set(s,n,a.get(s,n)+i*e.get(s,o))}for(o=l-1;o>=0;o--){for(n=0;n<h;n++)a.set(o,n,a.get(o,n)/this.Rdiag[o]);for(s=0;s<o;s++)for(n=0;n<h;n++)a.set(s,n,a.get(s,n)-a.get(o,n)*e.get(s,o))}return a.subMatrix(0,l-1,0,h-1)}isFullRank(){let t=this.QR.columns;for(let e=0;e<t;e++)if(0===this.Rdiag[e])return!1;return!0}get upperTriangularMatrix(){let t,e,r=this.QR,s=r.columns,n=new Rt(s,s);for(t=0;t<s;t++)for(e=0;e<s;e++)t<e?n.set(t,e,r.get(t,e)):t===e?n.set(t,e,this.Rdiag[t]):n.set(t,e,0);return n}get orthogonalMatrix(){let t,e,r,s,n=this.QR,o=n.rows,i=n.columns,h=new Rt(o,i);for(r=i-1;r>=0;r--){for(t=0;t<o;t++)h.set(t,r,0);for(h.set(r,r,1),e=r;e<i;e++)if(0!==n.get(r,r)){for(s=0,t=r;t<o;t++)s+=n.get(t,r)*h.get(t,e);for(s=-s/n.get(r,r),t=r;t<o;t++)h.set(t,e,h.get(t,e)+s*n.get(t,r))}}return h}}class Tt{constructor(t,e={}){if((t=Ft.checkMatrix(t)).isEmpty())throw new Error("Matrix must be non-empty");let r=t.rows,s=t.columns;const{computeLeftSingularVectors:n=!0,computeRightSingularVectors:o=!0,autoTranspose:i=!1}=e;let h,a=Boolean(n),l=Boolean(o),u=!1;if(r<s)if(i){h=t.transpose(),r=h.rows,s=h.columns,u=!0;let e=a;a=l,l=e}else h=t.clone(),console.warn("Computing SVD on a matrix with more columns than rows. Consider enabling autoTranspose");else h=t.clone();let c=Math.min(r,s),f=Math.min(r+1,s),g=new Float64Array(f),m=new Rt(r,c),p=new Rt(s,s),w=new Float64Array(s),d=new Float64Array(r),y=new Float64Array(f);for(let t=0;t<f;t++)y[t]=t;let b=Math.min(r-1,s),M=Math.max(0,Math.min(s-2,r)),x=Math.max(b,M);for(let t=0;t<x;t++){if(t<b){g[t]=0;for(let e=t;e<r;e++)g[t]=zt(g[t],h.get(e,t));if(0!==g[t]){h.get(t,t)<0&&(g[t]=-g[t]);for(let e=t;e<r;e++)h.set(e,t,h.get(e,t)/g[t]);h.set(t,t,h.get(t,t)+1)}g[t]=-g[t]}for(let e=t+1;e<s;e++){if(t<b&&0!==g[t]){let s=0;for(let n=t;n<r;n++)s+=h.get(n,t)*h.get(n,e);s=-s/h.get(t,t);for(let n=t;n<r;n++)h.set(n,e,h.get(n,e)+s*h.get(n,t))}w[e]=h.get(t,e)}if(a&&t<b)for(let e=t;e<r;e++)m.set(e,t,h.get(e,t));if(t<M){w[t]=0;for(let e=t+1;e<s;e++)w[t]=zt(w[t],w[e]);if(0!==w[t]){w[t+1]<0&&(w[t]=0-w[t]);for(let e=t+1;e<s;e++)w[e]/=w[t];w[t+1]+=1}if(w[t]=-w[t],t+1<r&&0!==w[t]){for(let e=t+1;e<r;e++)d[e]=0;for(let e=t+1;e<r;e++)for(let r=t+1;r<s;r++)d[e]+=w[r]*h.get(e,r);for(let e=t+1;e<s;e++){let s=-w[e]/w[t+1];for(let n=t+1;n<r;n++)h.set(n,e,h.get(n,e)+s*d[n])}}if(l)for(let e=t+1;e<s;e++)p.set(e,t,w[e])}}let v=Math.min(s,r+1);if(b<s&&(g[b]=h.get(b,b)),r<v&&(g[v-1]=0),M+1<v&&(w[M]=h.get(M,v-1)),w[v-1]=0,a){for(let t=b;t<c;t++){for(let e=0;e<r;e++)m.set(e,t,0);m.set(t,t,1)}for(let t=b-1;t>=0;t--)if(0!==g[t]){for(let e=t+1;e<c;e++){let s=0;for(let n=t;n<r;n++)s+=m.get(n,t)*m.get(n,e);s=-s/m.get(t,t);for(let n=t;n<r;n++)m.set(n,e,m.get(n,e)+s*m.get(n,t))}for(let e=t;e<r;e++)m.set(e,t,-m.get(e,t));m.set(t,t,1+m.get(t,t));for(let e=0;e<t-1;e++)m.set(e,t,0)}else{for(let e=0;e<r;e++)m.set(e,t,0);m.set(t,t,1)}}if(l)for(let t=s-1;t>=0;t--){if(t<M&&0!==w[t])for(let e=t+1;e<s;e++){let r=0;for(let n=t+1;n<s;n++)r+=p.get(n,t)*p.get(n,e);r=-r/p.get(t+1,t);for(let n=t+1;n<s;n++)p.set(n,e,p.get(n,e)+r*p.get(n,t))}for(let e=0;e<s;e++)p.set(e,t,0);p.set(t,t,1)}let E=v-1,S=0,k=Number.EPSILON;for(;v>0;){let t,e;for(t=v-2;t>=-1&&-1!==t;t--){const e=Number.MIN_VALUE+k*Math.abs(g[t]+Math.abs(g[t+1]));if(Math.abs(w[t])<=e||Number.isNaN(w[t])){w[t]=0;break}}if(t===v-2)e=4;else{let r;for(r=v-1;r>=t&&r!==t;r--){let e=(r!==v?Math.abs(w[r]):0)+(r!==t+1?Math.abs(w[r-1]):0);if(Math.abs(g[r])<=k*e){g[r]=0;break}}r===t?e=3:r===v-1?e=1:(e=2,t=r)}switch(t++,e){case 1:{let e=w[v-2];w[v-2]=0;for(let r=v-2;r>=t;r--){let n=zt(g[r],e),o=g[r]/n,i=e/n;if(g[r]=n,r!==t&&(e=-i*w[r-1],w[r-1]=o*w[r-1]),l)for(let t=0;t<s;t++)n=o*p.get(t,r)+i*p.get(t,v-1),p.set(t,v-1,-i*p.get(t,r)+o*p.get(t,v-1)),p.set(t,r,n)}break}case 2:{let e=w[t-1];w[t-1]=0;for(let s=t;s<v;s++){let n=zt(g[s],e),o=g[s]/n,i=e/n;if(g[s]=n,e=-i*w[s],w[s]=o*w[s],a)for(let e=0;e<r;e++)n=o*m.get(e,s)+i*m.get(e,t-1),m.set(e,t-1,-i*m.get(e,s)+o*m.get(e,t-1)),m.set(e,s,n)}break}case 3:{const e=Math.max(Math.abs(g[v-1]),Math.abs(g[v-2]),Math.abs(w[v-2]),Math.abs(g[t]),Math.abs(w[t])),n=g[v-1]/e,o=g[v-2]/e,i=w[v-2]/e,h=g[t]/e,u=w[t]/e,c=((o+n)*(o-n)+i*i)/2,f=n*i*(n*i);let d=0;0===c&&0===f||(d=c<0?0-Math.sqrt(c*c+f):Math.sqrt(c*c+f),d=f/(c+d));let y=(h+n)*(h-n)+d,b=h*u;for(let e=t;e<v-1;e++){let n=zt(y,b);0===n&&(n=Number.MIN_VALUE);let o=y/n,i=b/n;if(e!==t&&(w[e-1]=n),y=o*g[e]+i*w[e],w[e]=o*w[e]-i*g[e],b=i*g[e+1],g[e+1]=o*g[e+1],l)for(let t=0;t<s;t++)n=o*p.get(t,e)+i*p.get(t,e+1),p.set(t,e+1,-i*p.get(t,e)+o*p.get(t,e+1)),p.set(t,e,n);if(n=zt(y,b),0===n&&(n=Number.MIN_VALUE),o=y/n,i=b/n,g[e]=n,y=o*w[e]+i*g[e+1],g[e+1]=-i*w[e]+o*g[e+1],b=i*w[e+1],w[e+1]=o*w[e+1],a&&e<r-1)for(let t=0;t<r;t++)n=o*m.get(t,e)+i*m.get(t,e+1),m.set(t,e+1,-i*m.get(t,e)+o*m.get(t,e+1)),m.set(t,e,n)}w[v-2]=y,S+=1;break}case 4:if(g[t]<=0&&(g[t]=g[t]<0?-g[t]:0,l))for(let e=0;e<=E;e++)p.set(e,t,-p.get(e,t));for(;t<E&&!(g[t]>=g[t+1]);){let e=g[t];if(g[t]=g[t+1],g[t+1]=e,l&&t<s-1)for(let r=0;r<s;r++)e=p.get(r,t+1),p.set(r,t+1,p.get(r,t)),p.set(r,t,e);if(a&&t<r-1)for(let s=0;s<r;s++)e=m.get(s,t+1),m.set(s,t+1,m.get(s,t)),m.set(s,t,e);t++}S=0,v--}}if(u){let t=p;p=m,m=t}this.m=r,this.n=s,this.s=g,this.U=m,this.V=p}solve(t){let e=t,r=this.threshold,s=this.s.length,n=Rt.zeros(s,s);for(let t=0;t<s;t++)Math.abs(this.s[t])<=r?n.set(t,t,0):n.set(t,t,1/this.s[t]);let o=this.U,i=this.rightSingularVectors,h=i.mmul(n),a=i.rows,l=o.rows,u=Rt.zeros(a,l);for(let t=0;t<a;t++)for(let e=0;e<l;e++){let r=0;for(let n=0;n<s;n++)r+=h.get(t,n)*o.get(e,n);u.set(t,e,r)}return u.mmul(e)}solveForDiagonal(t){return this.solve(Rt.diag(t))}inverse(){let t=this.V,e=this.threshold,r=t.rows,s=t.columns,n=new Rt(r,this.s.length);for(let o=0;o<r;o++)for(let r=0;r<s;r++)Math.abs(this.s[r])>e&&n.set(o,r,t.get(o,r)/this.s[r]);let o=this.U,i=o.rows,h=o.columns,a=new Rt(r,i);for(let t=0;t<r;t++)for(let e=0;e<i;e++){let r=0;for(let s=0;s<h;s++)r+=n.get(t,s)*o.get(e,s);a.set(t,e,r)}return a}get condition(){return this.s[0]/this.s[Math.min(this.m,this.n)-1]}get norm2(){return this.s[0]}get rank(){let t=Math.max(this.m,this.n)*this.s[0]*Number.EPSILON,e=0,r=this.s;for(let s=0,n=r.length;s<n;s++)r[s]>t&&e++;return e}get diagonal(){return Array.from(this.s)}get threshold(){return Number.EPSILON/2*Math.max(this.m,this.n)*this.s[0]}get leftSingularVectors(){return this.U}get rightSingularVectors(){return this.V}get diagonalMatrix(){return Rt.diag(this.s)}}function Dt(t,e,r,s,n){let o=r*s*s,i=Rt.eye(e.length,e.length,o);const h=n(e);let a=new Float64Array(t.x.length);for(let e=0;e<t.x.length;e++)a[e]=h(t.x[e]);let l=function(t,e,r,s,n){const o=r.length,i=t.x.length;let h=new Array(o);for(let a=0;a<o;a++){h[a]=new Array(i);let o=r.slice();o[a]+=s;let l=n(o);for(let r=0;r<i;r++)h[a][r]=e[r]-l(t.x[r])}return new Rt(h)}(t,a,e,s,n),u=function(t,e){const r=t.x.length;let s=new Array(r);for(let n=0;n<r;n++)s[n]=[t.y[n]-e[n]];return new Rt(s)}(t,a),c=function(t,e=!1){return t=Ft.checkMatrix(t),e?new Tt(t).inverse():function(t,e,r=!1){return t=Ft.checkMatrix(t),e=Ft.checkMatrix(e),r?new Tt(t).solve(e):t.isSquare()?new Ct(t).solve(e):new It(t).solve(e)}(t,Rt.eye(t.rows))}(i.add(l.mmul(l.transpose())));return(e=(e=new Rt([e])).sub(c.mmul(l).mmul(u).mul(s).transpose())).to1DArray()}const Vt=1e-5,Ot=.001;class qt{learningRate=1;localConnectivity=1;minDist=.1;nComponents=2;nEpochs=0;nNeighbors=15;negativeSampleRate=5;random=Math.random;repulsionStrength=1;setOpMixRatio=1;spread=1;transformQueueSize=4;targetMetric="categorical";targetWeight=.5;targetNNeighbors=15;distanceFn=Pt;knnIndices;knnDistances;graph;X;isInitialized=!1;rpForest=[];initFromRandom;initFromTree;search;searchGraph;Y;embedding=[];optimizationState=new jt;get neighbors(){return this.nNeighbors}constructor(t={}){const e=e=>{void 0!==t[e]&&(this[e]=t[e])};e("distanceFn"),e("learningRate"),e("localConnectivity"),e("minDist"),e("nComponents"),e("nEpochs"),e("nNeighbors"),e("negativeSampleRate"),e("random"),e("repulsionStrength"),e("setOpMixRatio"),e("spread"),e("transformQueueSize"),this.targetNNeighbors=t.nNeighbors||this.nNeighbors||this.targetNNeighbors}fit(t){return this.initializeFit(t),this.optimizeLayout(),this.embedding}async fitAsync(t,e=(()=>!0)){return this.initializeFit(t),await this.optimizeLayoutAsync(e),this.embedding}setSupervisedProjection(t,e={}){this.Y=t,this.targetMetric=e.targetMetric||this.targetMetric,this.targetWeight=e.targetWeight||this.targetWeight,this.targetNNeighbors=e.targetNNeighbors||this.targetNNeighbors}setPrecomputedKNN(t,e){this.knnIndices=t,this.knnDistances=e}initializeFit(t){if(t.length<=this.nNeighbors)throw new Error(`Not enough data points (${t.length}) to create nNeighbors: ${this.nNeighbors}.  Add more data points or adjust the configuration.`);if(this.X===t&&this.isInitialized)return this.getNEpochs();if(this.X=t,!this.knnIndices&&!this.knnDistances){const e=this.nearestNeighbors(t);this.knnIndices=e.knnIndices,this.knnDistances=e.knnDistances}this.graph=this.fuzzySimplicialSet(t,this.nNeighbors,this.setOpMixRatio),this.makeSearchFns(),this.searchGraph=this.makeSearchGraph(t),this.processGraphForSupervisedProjection();const{head:e,tail:r,epochsPerSample:s}=this.initializeSimplicialSetEmbedding();return this.optimizationState.head=e,this.optimizationState.tail=r,this.optimizationState.epochsPerSample=s,this.initializeOptimization(),this.prepareForOptimizationLoop(),this.isInitialized=!0,this.getNEpochs()}makeSearchFns(){const{initFromTree:t,initFromRandom:e}=(r=this.distanceFn,{initFromRandom:function(t,e,s,n,o){for(let i=0;i<s.length;i++){const h=R(t,e.length,o);for(let t=0;t<h.length;t++)h[t]<0||I(n,i,r(e[h[t]],s[i]),h[t],1)}},initFromTree:function(t,e,s,n,o){for(let i=0;i<s.length;i++){const h=rt(s[i],t,o);for(let t=0;t<h.length;t++){if(h[t]<0)return;I(n,i,r(e[h[t]],s[i]),h[t],1)}}}});var r;this.initFromTree=t,this.initFromRandom=e,this.search=function(t){return function(e,r,s,n){const{indices:o,indptr:i}=K(r);for(let r=0;r<n.length;r++){const h=new Set(s[0][r]);for(;;){const a=q(s,r);if(-1===a)break;const l=o.slice(i[a],i[a+1]);for(const o of l)o===a||-1===o||h.has(o)||(T(s,r,t(e[o],n[r]),o,1),h.add(o))}}return s}}(this.distanceFn)}makeSearchGraph(t){const e=this.knnIndices,r=this.knnDistances,s=[t.length,t.length],n=new P([],[],[],s);for(let t=0;t<e.length;t++){const s=e[t],o=r[t];for(let e=0;e<s.length;e++){const r=s[e],i=o[e];i>0&&n.set(t,r,i)}}return X(n,j(n),((t,e)=>t>e?t:e))}transform(t){const e=this.X;if(void 0===e||0===e.length)throw new Error("No data has been fit.");let r=Math.floor(this.nNeighbors*this.transformQueueSize);r=Math.min(e.length,r);const s=function(t,e,r,s,n,o,i){const h=C(r.length,s);if(n(s,e,r,h,i),t)for(const s of t)o(s,e,r,h,i);return h}(this.rpForest,e,t,r,this.initFromRandom,this.initFromTree,this.random),n=this.search(e,this.searchGraph,s,t);let{indices:o,weights:i}=V(n);o=o.map((t=>t.slice(0,this.nNeighbors))),i=i.map((t=>t.slice(0,this.nNeighbors)));const h=Math.max(0,this.localConnectivity-1),{sigmas:a,rhos:l}=this.smoothKNNDistance(i,this.nNeighbors,h),{rows:u,cols:c,vals:f}=this.computeMembershipStrengths(o,i,a,l),g=[t.length,e.length];let m=new P(u,c,f,g);const p=K(Y(m,"l1")),w=t.length,d=function(t,e,r){const s=k(t.length).map((t=>k(r[0].length)));for(let n=0;n<t.length;n++)for(let o=0;o<t[0].length;o++)for(let i=0;i<r[0].length;i++){const h=t[n][o];s[n][i]+=e[n][o]*r[h][i]}return s}(F(p.indices,w,this.nNeighbors),F(p.values,w,this.nNeighbors),this.embedding),y=this.nEpochs?this.nEpochs/3:m.nRows<=1e4?100:30,b=m.getValues().reduce(((t,e)=>e>t?e:t),0);m=m.map((t=>t<b/y?0:t)),m=U(m);const M=this.makeEpochsPerSample(m.getValues(),y),x=m.getRows(),v=m.getCols();return this.assignOptimizationStateParameters({headEmbedding:d,tailEmbedding:this.embedding,head:x,tail:v,currentEpoch:0,nEpochs:y,nVertices:m.getDims()[1],epochsPerSample:M}),this.prepareForOptimizationLoop(),this.optimizeLayout()}processGraphForSupervisedProjection(){const{Y:t,X:e}=this;if(t){if(t.length!==e.length)throw new Error("Length of X and y must be equal");if("categorical"===this.targetMetric){const e=this.targetWeight<1?1/(1-this.targetWeight)*2.5:1e12;this.graph=this.categoricalSimplicialSetIntersection(this.graph,t,e)}}}step(){const{currentEpoch:t}=this.optimizationState;return t<this.getNEpochs()&&this.optimizeLayoutStep(t),this.optimizationState.currentEpoch}getEmbedding(){return this.embedding}nearestNeighbors(t){const{distanceFn:e,nNeighbors:r}=this,s=function(t,e){return function(r,s,n,o=10,i=50,h=.001,a=.5,l=!0){const u=r.length,c=C(r.length,n);for(let s=0;s<r.length;s++){const o=z(n,r.length,e);for(let e=0;e<o.length;e++){const n=t(r[s],r[o[e]]);I(c,s,n,o[e],1),I(c,o[e],n,s,1)}}if(l)for(let e=0;e<s.length;e++)for(let n=0;n<s[e].length&&!(s[e][n]<0);n++)for(let o=n+1;o<s[e].length&&!(s[e][o]<0);o++){const i=t(r[s[e][n]],r[s[e][o]]);I(c,s[e][n],i,s[e][o],1),I(c,s[e][o],i,s[e][n],1)}for(let s=0;s<o;s++){const s=D(c,u,n,i,e);let o=0;for(let n=0;n<u;n++)for(let h=0;h<i;h++){const l=Math.floor(s[0][n][h]);if(!(l<0||x(e)<a))for(let e=0;e<i;e++){const i=Math.floor(s[0][n][e]),a=s[2][n][h],u=s[2][n][e];if(i<0||!a&&!u)continue;const f=t(r[l],r[i]);o+=I(c,l,f,i,1),o+=I(c,i,f,l,1)}}if(o<=h*n*r.length)break}return V(c)}}(e,this.random),n=5+Math.floor(.5==(o=t.length**.5/20)?0:Math.round(o));var o;const i=Math.max(5,Math.floor(Math.round((t=>Math.log(t)/Math.log(2))(t.length))));this.rpForest=B(t,r,n,this.random);const h=function(t){if(t.length>0){const e=[];for(const r of t)e.push(...r.indices);return e}return[[-1]]}(this.rpForest),{indices:a,weights:l}=s(t,h,r,i);return{knnIndices:a,knnDistances:l}}fuzzySimplicialSet(t,e,r=1){const{knnIndices:s=[],knnDistances:n=[],localConnectivity:o}=this,{sigmas:i,rhos:h}=this.smoothKNNDistance(n,e,o),{rows:a,cols:l,vals:u}=this.computeMembershipStrengths(s,n,i,h),c=[t.length,t.length],f=new P(a,l,u,c),g=j(f),m=L(f,g),p=$(_(f,g),m);return _(W(p,r),W(m,1-r))}categoricalSimplicialSetIntersection(t,e,r,s=1){let n=function(t,e,r=1,s=5){return t.map(((t,n,o)=>-1===e[n]||-1===e[o]?t*Math.exp(-r):e[n]!==e[o]?t*Math.exp(-s):t))}(t,e,s,r);return n=U(n),function(t){const e=j(t=Y(t,"max"));return U(t=_(t,$(e,L(e,t))))}(n)}smoothKNNDistance(t,e,r=1,s=64,n=1){const o=Math.log(e)/Math.log(2)*n,i=k(t.length),h=k(t.length);for(let e=0;e<t.length;e++){let n=0,a=1/0,l=1;const u=t[e],c=u.filter((t=>t>0));if(c.length>=r){const t=Math.floor(r),s=r-t;t>0?(i[e]=c[t-1],s>Vt&&(i[e]+=s*(c[t]-c[t-1]))):i[e]=s*c[0]}else c.length>0&&(i[e]=A(c));for(let r=0;r<s;r++){let r=0;for(let s=1;s<t[e].length;s++){const n=t[e][s]-i[e];r+=n>0?Math.exp(-n/l):1}if(Math.abs(r-o)<Vt)break;r>o?(a=l,l=(n+a)/2):(n=l,a===1/0?l*=2:l=(n+a)/2)}if(h[e]=l,i[e]>0){const t=N(u);h[e]<Ot*t&&(h[e]=Ot*t)}else{const r=N(t.map(N));h[e]<Ot*r&&(h[e]=Ot*r)}}return{sigmas:h,rhos:i}}computeMembershipStrengths(t,e,r,s){const n=t.length,o=t[0].length,i=k(n*o),h=k(n*o),a=k(n*o);for(let l=0;l<n;l++)for(let n=0;n<o;n++){let u=0;-1!==t[l][n]&&(u=t[l][n]===l?0:e[l][n]-s[l]<=0?1:Math.exp(-(e[l][n]-s[l])/r[l]),i[l*o+n]=l,h[l*o+n]=t[l][n],a[l*o+n]=u)}return{rows:i,cols:h,vals:a}}initializeSimplicialSetEmbedding(){const t=this.getNEpochs(),{nComponents:e}=this,r=this.graph.getValues();let s=0;for(let t=0;t<r.length;t++){const e=r[t];s<r[t]&&(s=e)}const n=this.graph.map((e=>e<s/t?0:e));this.embedding=k(n.nRows).map((()=>k(e).map((()=>20*x(this.random)-10))));const o=[],i=[],h=[],a=n.getAll();for(let t=0;t<a.length;t++){const e=a[t];e.value&&(o.push(e.value),h.push(e.row),i.push(e.col))}return{head:i,tail:h,epochsPerSample:this.makeEpochsPerSample(o,t)}}makeEpochsPerSample(t,e){const r=S(t.length,-1),s=A(t),n=t.map((t=>t/s*e));return n.forEach(((t,s)=>{t>0&&(r[s]=e/n[s])})),r}assignOptimizationStateParameters(t){Object.assign(this.optimizationState,t)}prepareForOptimizationLoop(){const{repulsionStrength:t,learningRate:e,negativeSampleRate:r}=this,{epochsPerSample:s,headEmbedding:n,tailEmbedding:o}=this.optimizationState,i=n[0].length,h=n.length===o.length,a=s.map((t=>t/r)),l=[...a],u=[...s];this.assignOptimizationStateParameters({epochOfNextSample:u,epochOfNextNegativeSample:l,epochsPerNegativeSample:a,moveOther:h,initialAlpha:e,alpha:e,gamma:t,dim:i})}initializeOptimization(){const t=this.embedding,e=this.embedding,{head:r,tail:s,epochsPerSample:n}=this.optimizationState,o=this.getNEpochs(),i=this.graph.nCols,{a:h,b:a}=function(t,e){const r=function(t,e,r){return v(300).map(((t,r)=>0+r*((e-0)/299)))}(0,3*t).map((t=>t<e?1:t)),s=k(r.length).map(((s,n)=>r[n]>=e?Math.exp(-(r[n]-e)/t):s)),n={x:r,y:s},{parameterValues:o}=function(t,e,r={}){let{maxIterations:s=100,gradientDifference:n=.1,damping:o=0,errorTolerance:i=.01,minValues:h,maxValues:a,initialValues:l}=r;if(o<=0)throw new Error("The damping option must be a positive number");if(!t.x||!t.y)throw new Error("The data parameter must have x and y elements");if(!nt(t.x)||t.x.length<2||!nt(t.y)||t.y.length<2)throw new Error("The data parameter elements must be an array with more than 2 points");if(t.x.length!==t.y.length)throw new Error("The data parameter elements must have the same size");let u=l||new Array(e.length).fill(1),c=u.length;if(a=a||new Array(c).fill(Number.MAX_SAFE_INTEGER),h=h||new Array(c).fill(Number.MIN_SAFE_INTEGER),a.length!==h.length)throw new Error("minValues and maxValues must be the same size");if(!nt(u))throw new Error("initialValues must be an array");let f,g=ot(t,u,e),m=g<=i;for(f=0;f<s&&!m;f++){u=Dt(t,u,o,n,e);for(let t=0;t<c;t++)u[t]=Math.min(Math.max(h[t],u[t]),a[t]);if(g=ot(t,u,e),isNaN(g))break;m=g<=i}return{parameterValues:u,parameterError:g,iterations:f}}(n,(([t,e])=>r=>1/(1+t*r**(2*e))),{damping:1.5,initialValues:[.5,.5],gradientDifference:.1,maxIterations:100,errorTolerance:.01}),[i,h]=o;return{a:i,b:h}}(this.spread,this.minDist);this.assignOptimizationStateParameters({headEmbedding:t,tailEmbedding:e,head:r,tail:s,epochsPerSample:n,a:h,b:a,nEpochs:o,nVertices:i})}optimizeLayoutStep(t){const{optimizationState:e}=this,{head:r,tail:s,headEmbedding:n,tailEmbedding:o,epochsPerSample:i,epochOfNextSample:h,epochOfNextNegativeSample:a,epochsPerNegativeSample:l,moveOther:u,initialAlpha:c,alpha:f,gamma:g,a:m,b:p,dim:w,nEpochs:d,nVertices:y}=e;for(let e=0;e<i.length;e++){if(h[e]>t)continue;const c=r[e],d=s[e],b=n[c],x=o[d],v=_t(b,x);let E=0;v>0&&(E=-2*m*p*Math.pow(v,p-1),E/=m*Math.pow(v,p)+1);for(let t=0;t<w;t++){const e=Lt(E*(b[t]-x[t]),4);b[t]+=e*f,u&&(x[t]+=-e*f)}h[e]+=i[e];const S=Math.floor((t-a[e])/l[e]);for(let t=0;t<S;t++){const t=M(y,this.random),e=o[t],r=_t(b,e);let s=0;if(r>0)s=2*g*p,s/=(.001+r)*(m*Math.pow(r,p)+1);else if(c===t)continue;for(let t=0;t<w;t++){let r=4;s>0&&(r=Lt(s*(b[t]-e[t]),4)),b[t]+=r*f}}a[e]+=S*l[e]}return e.alpha=c*(1-t/d),e.currentEpoch+=1,n}optimizeLayoutAsync(t=(()=>!0)){return new Promise(((e,r)=>{const s=async()=>{try{const{nEpochs:r,currentEpoch:n}=this.optimizationState;this.embedding=this.optimizeLayoutStep(n);const o=this.optimizationState.currentEpoch,i=!1===t(o),h=o===r;if(i||h)return e(h);setTimeout((()=>s()),0)}catch(t){r(t)}};setTimeout((()=>s()),0)}))}optimizeLayout(t=(()=>!0)){let e=!1,r=[];for(;!e;){const{nEpochs:s,currentEpoch:n}=this.optimizationState;r=this.optimizeLayoutStep(n);const o=this.optimizationState.currentEpoch,i=!1===t(o);e=o===s||i}return r}getNEpochs(){const t=this.graph;if(this.nEpochs>0)return this.nEpochs;if(!t)return 200;const e=t.nRows;return e<=2500?500:e<=5e3?400:e<=7500?300:200}}function Pt(t,e){return Math.abs(t-e)}class jt{currentEpoch=0;headEmbedding=[];tailEmbedding=[];head=[];tail=[];epochsPerSample=[];epochOfNextSample=[];epochOfNextNegativeSample=[];epochsPerNegativeSample=[];moveOther=!0;initialAlpha=1;alpha=1;gamma=1;a=1.5769434603113077;b=.8950608779109733;dim=2;nEpochs=500;nVertices=0}function Lt(t,e){return t>e?e:t<-e?-e:t}function _t(t,e){let r=0;for(let s=0;s<t.length;s++)r+=Math.pow(t[s]-e[s],2);return r}var $t=r(2590),Wt=r(9657),Ut=r(6377),Yt=r.n(Ut);class Gt{perplexity;dim;epsilon;iter=0;N;P;Y;gains;ystep;random=Math.random;assert(t,e){if(!t)throw e||"Assertion failed"}getopt(t,e,r){return t.hasOwnProperty(e)?t[e]:r}returnV=!1;vValue=0;gaussRandom(){if(this.returnV)return this.returnV=!1,this.vValue;const t=2*this.random()-1,e=2*this.random()-1,r=t*t+e*e;if(0===r||r>1)return this.gaussRandom();const s=Math.sqrt(-2*Math.log(r)/r);return this.vValue=e*s,this.returnV=!0,t*s}randn(t,e){return t+this.gaussRandom()*e}zeros(t){if(void 0===t||isNaN(t))return new Float32Array;if("undefined"==typeof ArrayBuffer){const e=new Float32Array(t);for(let r=0;r<t;r++)e[r]=0;return e}return new Float32Array(t)}randn2d(t,e,r){const s=void 0!==r,n=new Array(t).fill(null).map((()=>new Float32Array(e)));if(s)for(let s=0;s<t;s++)n[s]=new Float32Array(e).fill(r);else for(let r=0;r<t;r++)for(let t=0;t<e;t++)n[r][t]=this.randn(0,1e-4);return n}l2(t,e){const r=t.length;let s=0;for(let n=0;n<r;n++){const r=t[n],o=e[n];s+=(r-o)*(r-o)}return s}xtod(t){const e=t.length,r=this.zeros(e*e);for(let s=0;s<e;s++)for(let n=s+1;n<e;n++){const o=this.l2(t[s],t[n]);r[s*e+n]=o,r[n*e+s]=o}return r}getIterSize(t){return t<=2e3?100:t<=3e3?90:t<=5e3?80:70}d2p(t,e,r,s){const n=(i=s,(t,e)=>i*t+e-Math.floor((t+2)*(t+1)/2)),o=new Float32Array(s*s);var i;for(let e=0;e<s;e++)for(let r=e+1;r<s;r++)o[e*s+r]=o[r*s+e]=t[n(e,r)];const h=s,a=Math.log(e),l=this.zeros(h*h),u=this.zeros(h);for(let t=0;t<h;t++){let e=-1/0,n=1/0,i=1,c=!1;const f=Math.floor(this.getIterSize(s)/5);let g=0;for(;!c;){let s=0;for(let e=0;e<h;e++){const r=t===e?0:Math.exp(-o[t*h+e]*i);u[e]=r,s+=r}let l=0;for(let t=0;t<h;t++){let e;e=0===s?0:u[t]/s,u[t]=e,e>1e-7&&(l-=e*Math.log(e))}l>a?(e=i,n===1/0?i*=2:i=(i+n)/2):(n=i,e===-1/0?i/=2:i=(i+e)/2),g++,Math.abs(l-a)<r&&(c=!0),g>=f&&(c=!0)}for(let e=0;e<h;e++)l[t*h+e]=u[e]}const c=this.zeros(h*h),f=2*h;for(let t=0;t<h;t++)for(let e=0;e<h;e++)c[t*h+e]=Math.max((l[t*h+e]+l[e*h+t])/f,1e-100);return c}sign(t){return t>0?1:t<0?-1:0}constructor(t){t=t||{},this.perplexity=this.getopt(t,"perplexity",30),this.dim=this.getopt(t,"dim",2),this.epsilon=this.getopt(t,"epsilon",10),this.random=this.getopt(t,"random",Math.random)}initDataRaw(t){const e=t.length,r=t[0].length;this.assert(e>0," X is empty? You must have some data!"),this.assert(r>0," X[0] is empty? Where is the data?");const s=this.xtod(t);this.P=this.d2p(s,this.perplexity,1e-4,r),this.N=e,this.initSolution()}initDataDist(t,e){const r=t.length;this.assert(r>0," X is empty? You must have some data!"),console.time("distances to matrix"),this.P=this.d2p(t,this.perplexity,1e-4,e),console.timeEnd("distances to matrix"),this.N=e,this.initSolution()}initSolution(){this.Y=this.randn2d(this.N,this.dim),this.gains=this.randn2d(this.N,this.dim,1),this.ystep=this.randn2d(this.N,this.dim,0),this.iter=0}getSolution(){return this.Y}step(){this.iter+=1;const t=this.N,e=this.costGrad(this.Y),r=e.cost,s=e.grad,n=this.zeros(this.dim);for(let e=0;e<t;e++)for(let t=0;t<this.dim;t++){const r=s[e][t],o=this.ystep[e][t],i=this.gains[e][t];let h=this.sign(r)===this.sign(o)?.8*i:i+.2;h<.01&&(h=.01),this.gains[e][t]=h;const a=(this.iter<250?.5:.8)*o-this.epsilon*h*s[e][t];this.ystep[e][t]=a,this.Y[e][t]+=a,n[t]+=this.Y[e][t]}for(let e=0;e<t;e++)for(let r=0;r<this.dim;r++)this.Y[e][r]-=n[r]/t;return r}debugGrad(){const t=this.N,e=this.costGrad(this.Y).grad,r=1e-5;for(let s=0;s<t;s++)for(let t=0;t<this.dim;t++){const n=this.Y[s][t];this.Y[s][t]=n+r;const o=this.costGrad(this.Y);this.Y[s][t]=n-r;const i=this.costGrad(this.Y),h=e[s][t],a=(o.cost-i.cost)/(2*r);console.log(s+","+t+": gradcheck analytic: "+h+" vs. numerical: "+a),this.Y[s][t]=n}}quArr;costGrad(t){const e=this.N,r=this.dim,s=this.P,n=this.iter<100?4:1;this.quArr??=this.zeros(e*e);let o=0;for(let s=0;s<e;s++)for(let n=s+1;n<e;n++){const i=1/(1+new Array(r).reduce(((e,r,o)=>e+Math.pow(t[s][o]-t[n][o],2)),0));this.quArr[s*e+n]=i,this.quArr[n*e+s]=i,o+=2*i}let i=0;const h=new Array(e).fill(null).map((()=>new Float32Array(r).fill(0)));for(let a=0;a<e;a++)for(let l=a+1;l<e;l++){const u=Math.max(this.quArr[a*e+l]/o,1e-100);i+=-s[a*e+l]*Math.log(u)*2;const c=4*(n*s[a*e+l]-u)*this.quArr[a*e+l];for(let e=0;e<r;e++)h[a][e]+=c*(t[a][e]-t[l][e]),h[l][e]+=c*(t[l][e]-t[a][e])}return{cost:i,grad:h}}}class Xt{data;weights;aggregationMethod;constructor(t){this.data=t.data,this.weights=t.weights,this.aggregationMethod=t.aggregationMethod}}class Kt extends 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e=t.randomSeed??Date(),r=Yt()(e);super(t),a("distanceFnames"in t),a("distanceFns"in t),this.distanceFnArgs=t.distanceFnArgs,this.distanceFns=t.distanceFns,this.progressFunc=t.progressFunc,this.distanceFnames=t.distanceFnames,this.vectors=new Array(this.data[0].length).fill(0).map(((t,e)=>e)),this.data[0].length<=(t.nNeighbors??15)&&(t.nNeighbors=this.data[0].length-1),t.random=r,this.reducer=new qt(t)}async transform(t){console.time("knn graph");const e=await(new $t._).multiColumnKNN(this.data,this.distanceFnames,this.reducer.neighbors,this.distanceFnArgs,this.weights,this.aggregationMethod);console.timeEnd("knn graph"),this.reducer.setPrecomputedKNN(e.knnIndexes,e.knnDistances),await new Promise((t=>{setTimeout((()=>{t()}),300)}));const r=await this.reducer.fitAsync(this.vectors,(t=>{this.progressFunc&&this.progressFunc(t,this.reducer.getNEpochs(),this.reducer.getEmbedding())}));return n=r,new Array(n.length).fill(0).map(((t,e)=>s.from(n[e])));var n}}const Bt={UMAP:Qt,"t-SNE":Kt};class Ht{reducer;constructor(t,e,r,s,n,o){const i=[];for(let e=0;e<r.length;++e){const s=new d(r[e]).getMeasure(o.distanceFnArgs[e]);i.push(s);let n=2048;for(let r=0;r<t[e].length;++r)if(t[e][r]&&t[e][r]._length){n=t[e][r]._length;break}if(h=r[e],"BitArray"==w[h])for(let r=0;r<t[e].length;++r)t[e][r]&&t[e][r]._data?t[e][r]=new Wt.Z(t[e][r]._data,t[e][r]._length):t[e][r]=new Wt.Z(n)}var h;"UMAP"==e?this.reducer=new Qt({data:t,distanceFnames:r,distanceFns:i,distanceFnArgs:o.distanceFnArgs,weights:s,aggregationMethod:n,...o}):"t-SNE"==e&&(this.reducer=new Kt({data:t,distanceFnames:r,distanceFns:i,distanceFnArgs:o.distanceFnArgs,weights:s,aggregationMethod:n,...o}))}async transform(t=!1){if(void 0===this.reducer)throw new Error("Reducer was not defined.");let e=await this.reducer.transform();var r;return t&&(r=e,e=new Array(r[0].length).fill(0).map(((t,e)=>new s(r.length).fill(0).map(((t,s)=>r[s][e]))))),e}static availableMetricsByType(t){return 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