@datagrok/bio 2.11.11 → 2.11.13

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (18) hide show
  1. package/dist/1.js +1 -1
  2. package/dist/1.js.map +1 -1
  3. package/dist/361.js +1 -1
  4. package/dist/361.js.map +1 -1
  5. package/dist/931.js +1 -1
  6. package/dist/931.js.map +1 -1
  7. package/dist/package-test.js +1 -1
  8. package/dist/package-test.js.map +1 -1
  9. package/dist/package.js +1 -1
  10. package/dist/package.js.map +1 -1
  11. package/files/tests/to-atomic-level-peptides-fasta-output.csv +139 -139
  12. package/files/tests/to-atomic-level-pt-fasta-2.mol +1 -1
  13. package/package.json +8 -8
  14. package/src/tests/WebLogo-positions-test.ts +3 -3
  15. package/src/tests/mm-distance-tests.ts +4 -4
  16. package/src/tests/splitters-test.ts +0 -3
  17. package/src/tests/to-atomic-level-tests.ts +3 -3
  18. package/src/viewers/vd-regions-viewer.ts +1 -1
package/dist/1.js CHANGED
@@ -1,2 +1,2 @@
1
- "use strict";(self.webpackChunkbio=self.webpackChunkbio||[]).push([[1],{6814:(t,e,n)=>{n.d(e,{k:()=>r});const r=t=>null==t},779:(t,e,n)=>{function r(t={}){const e=function(){if(!t||!t.scoringMatrix||!t.alphabetIndexes)return(t,e)=>t===e?0:1;if(t.scoringMatrix.length!==Object.keys(t.alphabetIndexes).length)throw new Error("Scoring matrix and alphabet indexes should have the same length");const e=t.alphabetIndexes,n=t.scoringMatrix,r=Math.min(...Object.keys(e).map((t=>t.charCodeAt(0))))+1,l=new Float32Array((n.length+r)*(n.length+r));return Object.entries(e).forEach((([t,r])=>{const a=n[r];Object.entries(e).forEach((([e,r])=>{l[t.charCodeAt(0)*n.length+e.charCodeAt(0)]=a[r]}))})),(t,e)=>l[t.charCodeAt(0)*n.length+e.charCodeAt(0)]}(),n=t?.threshold??0;return(t,r)=>{let l=0;const a=t.length,h=r.length,o=Math.max(a,h)*(1-n);a!==h&&(l=Math.abs(a-h));let c=0;for(let n=0;n<Math.min(a,h);n++)if(t[n]!==r[n]&&(c+=e(t[n],r[n]),c>o))return 1;return c+=l,c/=Math.max(a,h),c}}n.d(e,{j:()=>r})},458:(t,e,n)=>{n.d(e,{r:()=>l});var r=n(1811);function l(){return(t,e)=>(0,r.T)(t,e)/Math.max(t.length,e.length)}},6683:(t,e,n)=>{n.d(e,{n:()=>l});const r={gapOpen:8,gapExtend:2,scoringMatrix:[[4,-1,-2,-2,0,-1,-1,0,-2,-1,-1,-1,-1,-2,-1,1,0,-3,-2,0,-2,-1,0,-4],[-1,5,0,-2,-3,1,0,-2,0,-3,-2,2,-1,-3,-2,-1,-1,-3,-2,-3,-1,0,-1,-4],[-2,0,6,1,-3,0,0,0,1,-3,-3,0,-2,-3,-2,1,0,-4,-2,-3,3,0,-1,-4],[-2,-2,1,6,-3,0,2,-1,-1,-3,-4,-1,-3,-3,-1,0,-1,-4,-3,-3,4,1,-1,-4],[0,-3,-3,-3,9,-3,-4,-3,-3,-1,-1,-3,-1,-2,-3,-1,-1,-2,-2,-1,-3,-3,-2,-4],[-1,1,0,0,-3,5,2,-2,0,-3,-2,1,0,-3,-1,0,-1,-2,-1,-2,0,3,-1,-4],[-1,0,0,2,-4,2,5,-2,0,-3,-3,1,-2,-3,-1,0,-1,-3,-2,-2,1,4,-1,-4],[0,-2,0,-1,-3,-2,-2,6,-2,-4,-4,-2,-3,-3,-2,0,-2,-2,-3,-3,-1,-2,-1,-4],[-2,0,1,-1,-3,0,0,-2,8,-3,-3,-1,-2,-1,-2,-1,-2,-2,2,-3,0,0,-1,-4],[-1,-3,-3,-3,-1,-3,-3,-4,-3,4,2,-3,1,0,-3,-2,-1,-3,-1,3,-3,-3,-1,-4],[-1,-2,-3,-4,-1,-2,-3,-4,-3,2,4,-2,2,0,-3,-2,-1,-2,-1,1,-4,-3,-1,-4],[-1,2,0,-1,-3,1,1,-2,-1,-3,-2,5,-1,-3,-1,0,-1,-3,-2,-2,0,1,-1,-4],[-1,-1,-2,-3,-1,0,-2,-3,-2,1,2,-1,5,0,-2,-1,-1,-1,-1,1,-3,-1,-1,-4],[-2,-3,-3,-3,-2,-3,-3,-3,-1,0,0,-3,0,6,-4,-2,-2,1,3,-1,-3,-3,-1,-4],[-1,-2,-2,-1,-3,-1,-1,-2,-2,-3,-3,-1,-2,-4,7,-1,-1,-4,-3,-2,-2,-1,-2,-4],[1,-1,1,0,-1,0,0,0,-1,-2,-2,0,-1,-2,-1,4,1,-3,-2,-2,0,0,0,-4],[0,-1,0,-1,-1,-1,-1,-2,-2,-1,-1,-1,-1,-2,-1,1,5,-2,-2,0,-1,-1,0,-4],[-3,-3,-4,-4,-2,-2,-3,-2,-2,-3,-2,-3,-1,1,-4,-3,-2,11,2,-3,-4,-3,-2,-4],[-2,-2,-2,-3,-2,-1,-2,-3,2,-1,-1,-2,-1,3,-3,-2,-2,2,7,-1,-3,-2,-1,-4],[0,-3,-3,-3,-1,-2,-2,-3,-3,3,1,-2,1,-1,-2,-2,0,-3,-1,4,-3,-2,-1,-4],[-2,-1,3,4,-3,0,1,-1,0,-3,-4,0,-3,-3,-2,0,-1,-4,-3,-3,4,1,-1,-4],[-1,0,0,1,-3,3,4,-2,0,-3,-3,1,-1,-3,-1,0,-1,-3,-2,-2,1,4,-1,-4],[0,-1,-1,-1,-2,-1,-1,-1,-1,-1,-1,-1,-1,-1,-2,0,0,-2,-1,-1,-1,-1,-1,-4],[-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,1]],alphabetIndexes:{A:0,R:1,N:2,D:3,C:4,Q:5,E:6,G:7,H:8,I:9,L:10,K:11,M:12,F:13,P:14,S:15,T:16,W:17,Y:18,V:19,B:20,Z:21,X:22,"*":23}};function l(t){return(e,n)=>{const{gapOpen:l,gapExtend:a,scoringMatrix:h,alphabetIndexes:o}={...r,...t},c=[new Array(e.length+1).fill(0),new Array(e.length+1).fill(0)],s=new Array(e.length+1).fill(!1),i=new Array(e.length+1).fill(!1);let g=0,d=1;for(let t=1;t<e.length+1;t++)c[0][t]=-l-(t-1)*a;for(let t=1;t<n.length+1;t++){c[d][0]=-l-(t-1)*a;for(let r=1;r<e.length+1;r++){const f=c[g][r-1]+h[o[e[r-1]]][o[n[t-1]]],u=c[g][r]-(s[r]?a:l),A=c[d][r-1]-(i[r-1]?a:l);c[d][r]=Math.max(f,A,u),c[d][r]===f?(s[r]=!1,i[r]=!1):c[d][r]===A?(s[r]=!1,i[r]=!0):(s[r]=!0,i[r]=!1)}g=d,d=(d+1)%2}const f=e.split("").map((t=>h[o[t]][o[t]])).reduce(((t,e)=>t+e),0),u=n.split("").map((t=>h[o[t]][o[t]])).reduce(((t,e)=>t+e),0),A=Math.max(f,u);return(A-c[g][e.length])/A}}},1811:(t,e,n)=>{n.d(e,{T:()=>l});const r=new Uint32Array(65536),l=(t,e)=>{if(t.length<e.length){const n=e;e=t,t=n}return 0===e.length?t.length:t.length<=32?((t,e)=>{const n=t.length,l=e.length,a=1<<n-1;let h=-1,o=0,c=n,s=n;for(;s--;)r[t.charCodeAt(s)]|=1<<s;for(s=0;s<l;s++){let t=r[e.charCodeAt(s)];const n=t|o;t|=(t&h)+h^h,o|=~(t|h),h&=t,o&a&&c++,h&a&&c--,o=o<<1|1,h=h<<1|~(n|o),o&=n}for(s=n;s--;)r[t.charCodeAt(s)]=0;return c})(t,e):((t,e)=>{const n=e.length,l=t.length,a=[],h=[],o=Math.ceil(n/32),c=Math.ceil(l/32);for(let t=0;t<o;t++)h[t]=-1,a[t]=0;let s=0;for(;s<c-1;s++){let o=0,c=-1;const i=32*s,g=Math.min(32,l)+i;for(let e=i;e<g;e++)r[t.charCodeAt(e)]|=1<<e;for(let t=0;t<n;t++){const n=r[e.charCodeAt(t)],l=h[t/32|0]>>>t&1,s=a[t/32|0]>>>t&1,i=n|o,g=((n|s)&c)+c^c|n|s;let d=o|~(g|c),f=c&g;d>>>31^l&&(h[t/32|0]^=1<<t),f>>>31^s&&(a[t/32|0]^=1<<t),d=d<<1|l,f=f<<1|s,c=f|~(i|d),o=d&i}for(let e=i;e<g;e++)r[t.charCodeAt(e)]=0}let i=0,g=-1;const d=32*s,f=Math.min(32,l-d)+d;for(let e=d;e<f;e++)r[t.charCodeAt(e)]|=1<<e;let u=l;for(let t=0;t<n;t++){const n=r[e.charCodeAt(t)],o=h[t/32|0]>>>t&1,c=a[t/32|0]>>>t&1,s=n|i,d=((n|c)&g)+g^g|n|c;let f=i|~(d|g),A=g&d;u+=f>>>l-1&1,u-=A>>>l-1&1,f>>>31^o&&(h[t/32|0]^=1<<t),A>>>31^c&&(a[t/32|0]^=1<<t),f=f<<1|o,A=A<<1|c,g=A|~(s|f),i=f&s}for(let e=d;e<f;e++)r[t.charCodeAt(e)]=0;return u})(t,e)}}}]);
1
+ "use strict";(self.webpackChunkbio=self.webpackChunkbio||[]).push([[1],{6814:(t,e,n)=>{n.d(e,{k:()=>r});const r=t=>null==t},779:(t,e,n)=>{function r(t={}){const e=function(){if(!t||!t.scoringMatrix||!t.alphabetIndexes)return(t,e)=>t===e?0:1;if(t.scoringMatrix.length!==Object.keys(t.alphabetIndexes).length)throw new Error("Scoring matrix and alphabet indexes should have the same length");const e=t.alphabetIndexes,n=t.scoringMatrix,r=Math.min(...Object.keys(e).map((t=>t.charCodeAt(0))))+1,a=new Float32Array((n.length+r)*(n.length+r));return Object.entries(e).forEach((([t,r])=>{const h=n[r];Object.entries(e).forEach((([e,r])=>{a[t.charCodeAt(0)*n.length+e.charCodeAt(0)]=h[r]}))})),(t,e)=>a[t.charCodeAt(0)*n.length+e.charCodeAt(0)]}(),n=t?.threshold??0;return(t,r)=>{let a=0;const h=t.length,o=r.length,l=Math.max(h,o)*(1-n);h!==o&&(a=Math.abs(h-o));let c=0;for(let n=0;n<Math.min(h,o);n++)if(t[n]!==r[n]&&(c+=e(t[n],r[n]),c>l))return 1;return c+=a,c/=Math.max(h,o),c}}n.d(e,{j:()=>r})},458:(t,e,n)=>{n.d(e,{r:()=>a});var r=n(1811);function a(){return(t,e)=>(0,r.T)(t,e)/Math.max(t.length,e.length)}},6683:(t,e,n)=>{n.d(e,{n:()=>a});const r={gapOpen:1,gapExtend:.6,scoringMatrix:[[4,-1,-2,-2,0,-1,-1,0,-2,-1,-1,-1,-1,-2,-1,1,0,-3,-2,0,-2,-1,0,-4],[-1,5,0,-2,-3,1,0,-2,0,-3,-2,2,-1,-3,-2,-1,-1,-3,-2,-3,-1,0,-1,-4],[-2,0,6,1,-3,0,0,0,1,-3,-3,0,-2,-3,-2,1,0,-4,-2,-3,3,0,-1,-4],[-2,-2,1,6,-3,0,2,-1,-1,-3,-4,-1,-3,-3,-1,0,-1,-4,-3,-3,4,1,-1,-4],[0,-3,-3,-3,9,-3,-4,-3,-3,-1,-1,-3,-1,-2,-3,-1,-1,-2,-2,-1,-3,-3,-2,-4],[-1,1,0,0,-3,5,2,-2,0,-3,-2,1,0,-3,-1,0,-1,-2,-1,-2,0,3,-1,-4],[-1,0,0,2,-4,2,5,-2,0,-3,-3,1,-2,-3,-1,0,-1,-3,-2,-2,1,4,-1,-4],[0,-2,0,-1,-3,-2,-2,6,-2,-4,-4,-2,-3,-3,-2,0,-2,-2,-3,-3,-1,-2,-1,-4],[-2,0,1,-1,-3,0,0,-2,8,-3,-3,-1,-2,-1,-2,-1,-2,-2,2,-3,0,0,-1,-4],[-1,-3,-3,-3,-1,-3,-3,-4,-3,4,2,-3,1,0,-3,-2,-1,-3,-1,3,-3,-3,-1,-4],[-1,-2,-3,-4,-1,-2,-3,-4,-3,2,4,-2,2,0,-3,-2,-1,-2,-1,1,-4,-3,-1,-4],[-1,2,0,-1,-3,1,1,-2,-1,-3,-2,5,-1,-3,-1,0,-1,-3,-2,-2,0,1,-1,-4],[-1,-1,-2,-3,-1,0,-2,-3,-2,1,2,-1,5,0,-2,-1,-1,-1,-1,1,-3,-1,-1,-4],[-2,-3,-3,-3,-2,-3,-3,-3,-1,0,0,-3,0,6,-4,-2,-2,1,3,-1,-3,-3,-1,-4],[-1,-2,-2,-1,-3,-1,-1,-2,-2,-3,-3,-1,-2,-4,7,-1,-1,-4,-3,-2,-2,-1,-2,-4],[1,-1,1,0,-1,0,0,0,-1,-2,-2,0,-1,-2,-1,4,1,-3,-2,-2,0,0,0,-4],[0,-1,0,-1,-1,-1,-1,-2,-2,-1,-1,-1,-1,-2,-1,1,5,-2,-2,0,-1,-1,0,-4],[-3,-3,-4,-4,-2,-2,-3,-2,-2,-3,-2,-3,-1,1,-4,-3,-2,11,2,-3,-4,-3,-2,-4],[-2,-2,-2,-3,-2,-1,-2,-3,2,-1,-1,-2,-1,3,-3,-2,-2,2,7,-1,-3,-2,-1,-4],[0,-3,-3,-3,-1,-2,-2,-3,-3,3,1,-2,1,-1,-2,-2,0,-3,-1,4,-3,-2,-1,-4],[-2,-1,3,4,-3,0,1,-1,0,-3,-4,0,-3,-3,-2,0,-1,-4,-3,-3,4,1,-1,-4],[-1,0,0,1,-3,3,4,-2,0,-3,-3,1,-1,-3,-1,0,-1,-3,-2,-2,1,4,-1,-4],[0,-1,-1,-1,-2,-1,-1,-1,-1,-1,-1,-1,-1,-1,-2,0,0,-2,-1,-1,-1,-1,-1,-4],[-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,1]],alphabetIndexes:{A:0,R:1,N:2,D:3,C:4,Q:5,E:6,G:7,H:8,I:9,L:10,K:11,M:12,F:13,P:14,S:15,T:16,W:17,Y:18,V:19,B:20,Z:21,X:22,"*":23}};function a(t){const e=new Uint16Array(65536),{gapOpen:n,gapExtend:a,scoringMatrix:h,alphabetIndexes:o}={...r,...t};Object.entries(o).forEach((([t,n])=>e[t.charCodeAt(0)]=n));const l=[new Float32Array(1e4),new Float32Array(1e4)];return(t,r)=>{const o=new Array(t.length+1).fill(!1),c=new Array(t.length+1).fill(!1);let s=0,g=1;for(let e=1;e<t.length+1;e++)l[0][e]=-n-(e-1)*a,l[1][e]=0;for(let i=1;i<r.length+1;i++){l[g][0]=-n-(i-1)*a;for(let d=1;d<t.length+1;d++){const f=l[s][d-1]+h[e[t.charCodeAt(d-1)]][e[r.charCodeAt(i-1)]],A=l[s][d]-(o[d]?a:n),u=l[g][d-1]-(c[d-1]?a:n);l[g][d]=Math.max(f,u,A),l[g][d]===f?(o[d]=!1,c[d]=!1):l[g][d]===u?(o[d]=!1,c[d]=!0):(o[d]=!0,c[d]=!1)}s=g,g=(g+1)%2}const i=Math.max(t.length,r.length);return(i-l[s][t.length])/i}}},1811:(t,e,n)=>{n.d(e,{T:()=>a});const r=new Uint32Array(65536),a=(t,e)=>{if(t.length<e.length){const n=e;e=t,t=n}return 0===e.length?t.length:t.length<=32?((t,e)=>{const n=t.length,a=e.length,h=1<<n-1;let o=-1,l=0,c=n,s=n;for(;s--;)r[t.charCodeAt(s)]|=1<<s;for(s=0;s<a;s++){let t=r[e.charCodeAt(s)];const n=t|l;t|=(t&o)+o^o,l|=~(t|o),o&=t,l&h&&c++,o&h&&c--,l=l<<1|1,o=o<<1|~(n|l),l&=n}for(s=n;s--;)r[t.charCodeAt(s)]=0;return c})(t,e):((t,e)=>{const n=e.length,a=t.length,h=[],o=[],l=Math.ceil(n/32),c=Math.ceil(a/32);for(let t=0;t<l;t++)o[t]=-1,h[t]=0;let s=0;for(;s<c-1;s++){let l=0,c=-1;const g=32*s,i=Math.min(32,a)+g;for(let e=g;e<i;e++)r[t.charCodeAt(e)]|=1<<e;for(let t=0;t<n;t++){const n=r[e.charCodeAt(t)],a=o[t/32|0]>>>t&1,s=h[t/32|0]>>>t&1,g=n|l,i=((n|s)&c)+c^c|n|s;let d=l|~(i|c),f=c&i;d>>>31^a&&(o[t/32|0]^=1<<t),f>>>31^s&&(h[t/32|0]^=1<<t),d=d<<1|a,f=f<<1|s,c=f|~(g|d),l=d&g}for(let e=g;e<i;e++)r[t.charCodeAt(e)]=0}let g=0,i=-1;const d=32*s,f=Math.min(32,a-d)+d;for(let e=d;e<f;e++)r[t.charCodeAt(e)]|=1<<e;let A=a;for(let t=0;t<n;t++){const n=r[e.charCodeAt(t)],l=o[t/32|0]>>>t&1,c=h[t/32|0]>>>t&1,s=n|g,d=((n|c)&i)+i^i|n|c;let f=g|~(d|i),u=i&d;A+=f>>>a-1&1,A-=u>>>a-1&1,f>>>31^l&&(o[t/32|0]^=1<<t),u>>>31^c&&(h[t/32|0]^=1<<t),f=f<<1|l,u=u<<1|c,i=u|~(s|f),g=f&s}for(let e=d;e<f;e++)r[t.charCodeAt(e)]=0;return A})(t,e)}}}]);
2
2
  //# sourceMappingURL=1.js.map
package/dist/1.js.map CHANGED
@@ -1 +1 @@
1
- {"version":3,"file":"1.js","mappings":"wGAAO,MAAMA,EAASC,GAAMA,O,gBCArB,SAASC,EAAQC,EAAO,CAAC,GA0B5B,MAAMC,EAzBN,WACI,IAAKD,IAASA,EAAKE,gBAAkBF,EAAKG,gBACtC,MAAO,CAACC,EAAGC,IAAMD,IAAMC,EAAI,EAAI,EACnC,GAAIL,EAAKE,cAAcI,SAAWC,OAAOC,KAAKR,EAAKG,iBAAiBG,OAChE,MAAM,IAAIG,MAAM,mEACpB,MAAMC,EAAUV,EAAKG,gBACfQ,EAASX,EAAKE,cAGdU,EAAcC,KAAKC,OAAOP,OAAOC,KAAKE,GAASK,KAAIC,GAAKA,EAAEC,WAAW,MAAO,EAC5EC,EAAgB,IAAIC,cAAcR,EAAOL,OAASM,IAAgBD,EAAOL,OAASM,IAWxF,OAVAL,OAAOa,QAAQV,GAASW,SAAQ,EAAEC,EAAKC,MAGnC,MAAMC,EAAYb,EAAOY,GACzBhB,OAAOa,QAAQV,GAASW,SAAQ,EAAEI,EAAMC,MAEpCR,EAAcI,EAAIL,WAAW,GAAKN,EAAOL,OAASmB,EAAKR,WAAW,IAAMO,EAAUE,EAAO,GAE3F,IAEC,CAACtB,EAAGC,IACAa,EAAcd,EAAEa,WAAW,GAAKN,EAAOL,OAASD,EAAEY,WAAW,GAE5E,CACkBU,GACZC,EAAY5B,GAAM4B,WAAa,EACrC,MAAO,CAACC,EAAMC,KAGV,IAAIC,EAAO,EACX,MAAMC,EAAMH,EAAKvB,OACX2B,EAAMH,EAAKxB,OACX4B,EAAiBrB,KAAKsB,IAAIH,EAAKC,IAAQ,EAAIL,GAC7CI,IAAQC,IACRF,EAAOlB,KAAKuB,IAAIJ,EAAMC,IAC1B,IAAII,EAAS,EACb,IAAK,IAAIC,EAAI,EAAGA,EAAIzB,KAAKC,IAAIkB,EAAKC,GAAMK,IACpC,GAAIT,EAAKS,KAAOR,EAAKQ,KACjBD,GAAUpC,EAAU4B,EAAKS,GAAIR,EAAKQ,IAC9BD,EAASH,GACT,OAAO,EAKnB,OAFAG,GAAUN,EACVM,GAAUxB,KAAKsB,IAAIH,EAAKC,GACjBI,CAAM,CAErB,C,+DChDO,SAASE,IACZ,MAAO,CAACV,EAAMC,KACH,OAASD,EAAMC,GAAQjB,KAAKsB,IAAIN,EAAKvB,OAAQwB,EAAKxB,OAEjE,C,kCCJA,MA8BMkC,EAAc,CAChBC,QAAS,EACTC,UAAW,EACXxC,cAjCa,CAAC,CAAC,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,EAAG,GAAI,GAAI,EAAG,GAAI,GACrG,EAAE,EAAG,EAAG,GAAI,GAAI,EAAG,EAAG,GAAI,EAAG,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GACvF,EAAE,EAAG,EAAG,EAAG,GAAI,EAAG,EAAG,EAAG,EAAG,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GAClF,EAAE,GAAI,EAAG,EAAG,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GACvF,CAAC,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAC5F,EAAE,EAAG,EAAG,EAAG,GAAI,EAAG,EAAG,GAAI,EAAG,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GACnF,EAAE,EAAG,EAAG,EAAG,GAAI,EAAG,EAAG,GAAI,EAAG,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GACpF,CAAC,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAC1F,EAAE,EAAG,EAAG,GAAI,GAAI,EAAG,EAAG,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,EAAG,EAAG,GAAI,GAAI,GACtF,EAAE,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GACzF,EAAE,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GACzF,EAAE,EAAG,EAAG,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GACtF,EAAE,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GACxF,EAAE,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GACxF,EAAE,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAC7F,CAAC,GAAI,EAAG,EAAG,GAAI,EAAG,EAAG,EAAG,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,EAAG,EAAG,EAAG,GAAI,GAClF,CAAC,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,EAAG,GAAI,GAAI,EAAG,GAAI,GACxF,EAAE,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAC5F,EAAE,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAC1F,CAAC,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,EAAG,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GACxF,EAAE,GAAI,EAAG,EAAG,GAAI,EAAG,EAAG,GAAI,EAAG,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GACrF,EAAE,EAAG,EAAG,EAAG,GAAI,EAAG,EAAG,GAAI,EAAG,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GACpF,CAAC,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAC3F,EAAE,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,IAW7FC,gBATgB,CAChB,EAAK,EAAG,EAAK,EAAG,EAAK,EAAG,EAAK,EAAG,EAAK,EAAG,EAAK,EAAG,EAAK,EAAG,EAAK,EAAG,EAAK,EACrE,EAAK,EAAG,EAAK,GAAI,EAAK,GAAI,EAAK,GAAI,EAAK,GAAI,EAAK,GAAI,EAAK,GAAI,EAAK,GACnE,EAAK,GAAI,EAAK,GAAI,EAAK,GAAI,EAAK,GAAI,EAAK,GAAI,EAAK,GAAI,IAAK,KAYxD,SAASwC,EAAe3C,GAC3B,MAAO,CAAC6B,EAAMC,KACV,MAAM,QAAEW,EAAO,UAAEC,EAAS,cAAExC,EAAa,gBAAEC,GAAoB,IAAKqC,KAAgBxC,GAG9EW,EAAS,CACX,IAAIiC,MAAMf,EAAKvB,OAAS,GAAGuC,KAAK,GAChC,IAAID,MAAMf,EAAKvB,OAAS,GAAGuC,KAAK,IAI9BC,EAAe,IAAIF,MAAMf,EAAKvB,OAAS,GAAGuC,MAAK,GAC/CE,EAAiB,IAAIH,MAAMf,EAAKvB,OAAS,GAAGuC,MAAK,GAGvD,IAAIG,EAAU,EACVC,EAAU,EAEd,IAAK,IAAIX,EAAI,EAAGA,EAAIT,EAAKvB,OAAS,EAAGgC,IACjC3B,EAAO,GAAG2B,IAAMG,GAAWH,EAAI,GAAKI,EAExC,IAAK,IAAIJ,EAAI,EAAGA,EAAIR,EAAKxB,OAAS,EAAGgC,IAAK,CACtC3B,EAAOsC,GAAS,IAAMR,GAAWH,EAAI,GAAKI,EAC1C,IAAK,IAAIQ,EAAI,EAAGA,EAAIrB,EAAKvB,OAAS,EAAG4C,IAAK,CACtC,MAAMC,EAAWxC,EAAOqC,GAASE,EAAI,GAAKhD,EAAcC,EAAgB0B,EAAKqB,EAAI,KAAK/C,EAAgB2B,EAAKQ,EAAI,KACzGc,EAAMzC,EAAOqC,GAASE,IAAMJ,EAAaI,GAAKR,EAAYD,GAC1DY,EAAO1C,EAAOsC,GAASC,EAAI,IAAMH,EAAeG,EAAI,GAAKR,EAAYD,GAC3E9B,EAAOsC,GAASC,GAAKrC,KAAKsB,IAAIgB,EAAUE,EAAMD,GAE1CzC,EAAOsC,GAASC,KAAOC,GACvBL,EAAaI,IAAK,EAClBH,EAAeG,IAAK,GAEfvC,EAAOsC,GAASC,KAAOG,GAC5BP,EAAaI,IAAK,EAClBH,EAAeG,IAAK,IAGpBJ,EAAaI,IAAK,EAClBH,EAAeG,IAAK,EAE5B,CAEAF,EAAUC,EACVA,GAAWA,EAAU,GAAK,CAC9B,CAGA,MAAMK,EAAmBzB,EAAK0B,MAAM,IAAIxC,KAAKyC,GAAMtD,EAAcC,EAAgBqD,IAAIrD,EAAgBqD,MAChGC,QAAO,CAACrD,EAAGC,IAAMD,EAAIC,GAAG,GACvBqD,EAAmB5B,EAAKyB,MAAM,IAAIxC,KAAKyC,GAAMtD,EAAcC,EAAgBqD,IAAIrD,EAAgBqD,MAChGC,QAAO,CAACrD,EAAGC,IAAMD,EAAIC,GAAG,GACvBsD,EAAW9C,KAAKsB,IAAImB,EAAkBI,GAC5C,OAAQC,EAAWhD,EAAOqC,GAASnB,EAAKvB,SAAWqD,CAAQ,CAEnE,C,kCChGA,MAAMC,EAAM,IAAIC,YAAY,OA+GtBC,EAAW,CAAC1D,EAAGC,KACjB,GAAID,EAAEE,OAASD,EAAEC,OAAQ,CACrB,MAAMyD,EAAM1D,EACZA,EAAID,EACJA,EAAI2D,CACR,CACA,OAAiB,IAAb1D,EAAEC,OACKF,EAAEE,OAETF,EAAEE,QAAU,GAvHH,EAACF,EAAGC,KACjB,MAAM2D,EAAI5D,EAAEE,OACN2D,EAAI5D,EAAEC,OACN4D,EAAM,GAAMF,EAAI,EACtB,IAAIG,GAAM,EACNC,EAAK,EACLC,EAAKL,EACL1B,EAAI0B,EACR,KAAO1B,KACHsB,EAAIxD,EAAEa,WAAWqB,KAAO,GAAKA,EAEjC,IAAKA,EAAI,EAAGA,EAAI2B,EAAG3B,IAAK,CACpB,IAAIgC,EAAKV,EAAIvD,EAAEY,WAAWqB,IAC1B,MAAMiC,EAAKD,EAAKF,EAChBE,IAAQA,EAAKH,GAAMA,EAAMA,EACzBC,KAAQE,EAAKH,GACbA,GAAMG,EACFF,EAAKF,GACLG,IAEAF,EAAKD,GACLG,IAEJD,EAAMA,GAAM,EAAK,EACjBD,EAAMA,GAAM,IAAOI,EAAKH,GACxBA,GAAMG,CACV,CAEA,IADAjC,EAAI0B,EACG1B,KACHsB,EAAIxD,EAAEa,WAAWqB,IAAM,EAE3B,OAAO+B,CAAE,EAyFEG,CAASpE,EAAGC,GAvFX,EAACA,EAAGD,KAChB,MAAM4D,EAAI5D,EAAEE,OACN2D,EAAI5D,EAAEC,OACNmE,EAAM,GACNC,EAAM,GACNC,EAAQ9D,KAAK+D,KAAKZ,EAAI,IACtBa,EAAQhE,KAAK+D,KAAKX,EAAI,IAC5B,IAAK,IAAI3B,EAAI,EAAGA,EAAIqC,EAAOrC,IACvBoC,EAAIpC,IAAM,EACVmC,EAAInC,GAAK,EAEb,IAAIY,EAAI,EACR,KAAOA,EAAI2B,EAAQ,EAAG3B,IAAK,CACvB,IAAIkB,EAAK,EACLD,GAAM,EACV,MAAMW,EAAY,GAAJ5B,EACR6B,EAAOlE,KAAKC,IAAI,GAAImD,GAAKa,EAC/B,IAAK,IAAI9D,EAAI8D,EAAO9D,EAAI+D,EAAM/D,IAC1B4C,EAAIvD,EAAEY,WAAWD,KAAO,GAAKA,EAEjC,IAAK,IAAIsB,EAAI,EAAGA,EAAI0B,EAAG1B,IAAK,CACxB,MAAMgC,EAAKV,EAAIxD,EAAEa,WAAWqB,IACtB0C,EAAMN,EAAKpC,EAAI,GAAM,KAAOA,EAAK,EACjC2C,EAAMR,EAAKnC,EAAI,GAAM,KAAOA,EAAK,EACjCiC,EAAKD,EAAKF,EACVc,IAASZ,EAAKW,GAAMd,GAAMA,EAAMA,EAAMG,EAAKW,EACjD,IAAIE,EAAKf,IAAOc,EAAKf,GACjBiB,EAAKjB,EAAKe,EACTC,IAAO,GAAMH,IACdN,EAAKpC,EAAI,GAAM,IAAM,GAAKA,GAEzB8C,IAAO,GAAMH,IACdR,EAAKnC,EAAI,GAAM,IAAM,GAAKA,GAE9B6C,EAAMA,GAAM,EAAKH,EACjBI,EAAMA,GAAM,EAAKH,EACjBd,EAAKiB,IAAOb,EAAKY,GACjBf,EAAKe,EAAKZ,CACd,CACA,IAAK,IAAIvD,EAAI8D,EAAO9D,EAAI+D,EAAM/D,IAC1B4C,EAAIvD,EAAEY,WAAWD,IAAM,CAE/B,CACA,IAAIoD,EAAK,EACLD,GAAM,EACV,MAAMW,EAAY,GAAJ5B,EACR6B,EAAOlE,KAAKC,IAAI,GAAImD,EAAIa,GAASA,EACvC,IAAK,IAAI9D,EAAI8D,EAAO9D,EAAI+D,EAAM/D,IAC1B4C,EAAIvD,EAAEY,WAAWD,KAAO,GAAKA,EAEjC,IAAIqE,EAAQpB,EACZ,IAAK,IAAI3B,EAAI,EAAGA,EAAI0B,EAAG1B,IAAK,CACxB,MAAMgC,EAAKV,EAAIxD,EAAEa,WAAWqB,IACtB0C,EAAMN,EAAKpC,EAAI,GAAM,KAAOA,EAAK,EACjC2C,EAAMR,EAAKnC,EAAI,GAAM,KAAOA,EAAK,EACjCiC,EAAKD,EAAKF,EACVc,IAASZ,EAAKW,GAAMd,GAAMA,EAAMA,EAAMG,EAAKW,EACjD,IAAIE,EAAKf,IAAOc,EAAKf,GACjBiB,EAAKjB,EAAKe,EACdG,GAAUF,IAAQlB,EAAI,EAAM,EAC5BoB,GAAUD,IAAQnB,EAAI,EAAM,EACvBkB,IAAO,GAAMH,IACdN,EAAKpC,EAAI,GAAM,IAAM,GAAKA,GAEzB8C,IAAO,GAAMH,IACdR,EAAKnC,EAAI,GAAM,IAAM,GAAKA,GAE9B6C,EAAMA,GAAM,EAAKH,EACjBI,EAAMA,GAAM,EAAKH,EACjBd,EAAKiB,IAAOb,EAAKY,GACjBf,EAAKe,EAAKZ,CACd,CACA,IAAK,IAAIvD,EAAI8D,EAAO9D,EAAI+D,EAAM/D,IAC1B4C,EAAIvD,EAAEY,WAAWD,IAAM,EAE3B,OAAOqE,CAAK,EAcLC,CAAQlF,EAAGC,EAAE,C","sources":["webpack://bio/./node_modules/@datagrok-libraries/ml/src/distance-matrix/utils.js","webpack://bio/./node_modules/@datagrok-libraries/ml/src/macromolecule-distance-functions/hamming.js","webpack://bio/./node_modules/@datagrok-libraries/ml/src/macromolecule-distance-functions/levenstein.js","webpack://bio/./node_modules/@datagrok-libraries/ml/src/macromolecule-distance-functions/needleman-wunsch.js","webpack://bio/./node_modules/fastest-levenshtein/esm/mod.js"],"sourcesContent":["export const isNil = (x) => x === null || x === undefined;\n//# sourceMappingURL=data:application/json;base64,eyJ2ZXJzaW9uIjozLCJmaWxlIjoidXRpbHMuanMiLCJzb3VyY2VSb290IjoiIiwic291cmNlcyI6WyJ1dGlscy50cyJdLCJuYW1lcyI6W10sIm1hcHBpbmdzIjoiQUFBQSxNQUFNLENBQUMsTUFBTSxLQUFLLEdBQUcsQ0FBQyxDQUFNLEVBQUUsRUFBRSxDQUFDLENBQUMsS0FBSyxJQUFJLElBQUksQ0FBQyxLQUFLLFNBQVMsQ0FBQyIsInNvdXJjZXNDb250ZW50IjpbImV4cG9ydCBjb25zdCBpc05pbCA9ICh4OiBhbnkpID0+IHggPT09IG51bGwgfHwgeCA9PT0gdW5kZWZpbmVkO1xuIl19","export function hamming(args = {}) {\n function getDistanceF() {\n if (!args || !args.scoringMatrix || !args.alphabetIndexes)\n return (a, b) => a === b ? 0 : 1;\n if (args.scoringMatrix.length !== Object.keys(args.alphabetIndexes).length)\n throw new Error('Scoring matrix and alphabet indexes should have the same length');\n const indexes = args.alphabetIndexes;\n const matrix = args.scoringMatrix;\n //const matrixMap = new Map<string, Map<string, number>>();\n //const map2: any = {};\n const minCharCode = Math.min(...Object.keys(indexes).map(k => k.charCodeAt(0))) + 1;\n const scorringArray = new Float32Array((matrix.length + minCharCode) * (matrix.length + minCharCode));\n Object.entries(indexes).forEach(([key, index]) => {\n //matrixMap.set(key, new Map<string, number>());\n //map2[key] = {};\n const matrixRow = matrix[index];\n Object.entries(indexes).forEach(([key2, index2]) => {\n //matrixMap.get(key)!.set(key2, matrixRow[index2]);\n scorringArray[key.charCodeAt(0) * matrix.length + key2.charCodeAt(0)] = matrixRow[index2];\n //map2[key][key2] = matrixRow[index2];\n });\n });\n return (a, b) => {\n return scorringArray[a.charCodeAt(0) * matrix.length + b.charCodeAt(0)];\n };\n }\n const distanceF = getDistanceF();\n const threshold = args?.threshold ?? 0;\n return (seq1, seq2) => {\n // hamming distance should only be used with same size strings,\n // but still, lets add a check and if they are not same length add the difference to the result\n let diff = 0;\n const s1l = seq1.length;\n const s2l = seq2.length;\n const thresholdLimit = Math.max(s1l, s2l) * (1 - threshold);\n if (s1l !== s2l)\n diff = Math.abs(s1l - s2l);\n let result = 0;\n for (let i = 0; i < Math.min(s1l, s2l); i++) {\n if (seq1[i] !== seq2[i]) {\n result += distanceF(seq1[i], seq2[i]);\n if (result > thresholdLimit)\n return 1;\n }\n }\n result += diff;\n result /= Math.max(s1l, s2l);\n return result;\n };\n}\n//# sourceMappingURL=data:application/json;base64,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","import { distance } from 'fastest-levenshtein';\nexport function levenstein() {\n return (seq1, seq2) => {\n return distance(seq1, seq2) / Math.max(seq1.length, seq2.length);\n };\n}\n//# sourceMappingURL=data:application/json;base64,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","// Blosum 62 matrix for protein sequences\nconst BLOSUM62 = [[4, -1, -2, -2, 0, -1, -1, 0, -2, -1, -1, -1, -1, -2, -1, 1, 0, -3, -2, 0, -2, -1, 0, -4],\n [-1, 5, 0, -2, -3, 1, 0, -2, 0, -3, -2, 2, -1, -3, -2, -1, -1, -3, -2, -3, -1, 0, -1, -4],\n [-2, 0, 6, 1, -3, 0, 0, 0, 1, -3, -3, 0, -2, -3, -2, 1, 0, -4, -2, -3, 3, 0, -1, -4],\n [-2, -2, 1, 6, -3, 0, 2, -1, -1, -3, -4, -1, -3, -3, -1, 0, -1, -4, -3, -3, 4, 1, -1, -4],\n [0, -3, -3, -3, 9, -3, -4, -3, -3, -1, -1, -3, -1, -2, -3, -1, -1, -2, -2, -1, -3, -3, -2, -4],\n [-1, 1, 0, 0, -3, 5, 2, -2, 0, -3, -2, 1, 0, -3, -1, 0, -1, -2, -1, -2, 0, 3, -1, -4],\n [-1, 0, 0, 2, -4, 2, 5, -2, 0, -3, -3, 1, -2, -3, -1, 0, -1, -3, -2, -2, 1, 4, -1, -4],\n [0, -2, 0, -1, -3, -2, -2, 6, -2, -4, -4, -2, -3, -3, -2, 0, -2, -2, -3, -3, -1, -2, -1, -4],\n [-2, 0, 1, -1, -3, 0, 0, -2, 8, -3, -3, -1, -2, -1, -2, -1, -2, -2, 2, -3, 0, 0, -1, -4],\n [-1, -3, -3, -3, -1, -3, -3, -4, -3, 4, 2, -3, 1, 0, -3, -2, -1, -3, -1, 3, -3, -3, -1, -4],\n [-1, -2, -3, -4, -1, -2, -3, -4, -3, 2, 4, -2, 2, 0, -3, -2, -1, -2, -1, 1, -4, -3, -1, -4],\n [-1, 2, 0, -1, -3, 1, 1, -2, -1, -3, -2, 5, -1, -3, -1, 0, -1, -3, -2, -2, 0, 1, -1, -4],\n [-1, -1, -2, -3, -1, 0, -2, -3, -2, 1, 2, -1, 5, 0, -2, -1, -1, -1, -1, 1, -3, -1, -1, -4],\n [-2, -3, -3, -3, -2, -3, -3, -3, -1, 0, 0, -3, 0, 6, -4, -2, -2, 1, 3, -1, -3, -3, -1, -4],\n [-1, -2, -2, -1, -3, -1, -1, -2, -2, -3, -3, -1, -2, -4, 7, -1, -1, -4, -3, -2, -2, -1, -2, -4],\n [1, -1, 1, 0, -1, 0, 0, 0, -1, -2, -2, 0, -1, -2, -1, 4, 1, -3, -2, -2, 0, 0, 0, -4],\n [0, -1, 0, -1, -1, -1, -1, -2, -2, -1, -1, -1, -1, -2, -1, 1, 5, -2, -2, 0, -1, -1, 0, -4],\n [-3, -3, -4, -4, -2, -2, -3, -2, -2, -3, -2, -3, -1, 1, -4, -3, -2, 11, 2, -3, -4, -3, -2, -4],\n [-2, -2, -2, -3, -2, -1, -2, -3, 2, -1, -1, -2, -1, 3, -3, -2, -2, 2, 7, -1, -3, -2, -1, -4],\n [0, -3, -3, -3, -1, -2, -2, -3, -3, 3, 1, -2, 1, -1, -2, -2, 0, -3, -1, 4, -3, -2, -1, -4],\n [-2, -1, 3, 4, -3, 0, 1, -1, 0, -3, -4, 0, -3, -3, -2, 0, -1, -4, -3, -3, 4, 1, -1, -4],\n [-1, 0, 0, 1, -3, 3, 4, -2, 0, -3, -3, 1, -1, -3, -1, 0, -1, -3, -2, -2, 1, 4, -1, -4],\n [0, -1, -1, -1, -2, -1, -1, -1, -1, -1, -1, -1, -1, -1, -2, 0, 0, -2, -1, -1, -1, -1, -1, -4],\n [-4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, 1]];\n// Protein indexes for BLOSUM matrix\nconst ProtIndexes = {\n 'A': 0, 'R': 1, 'N': 2, 'D': 3, 'C': 4, 'Q': 5, 'E': 6, 'G': 7, 'H': 8,\n 'I': 9, 'L': 10, 'K': 11, 'M': 12, 'F': 13, 'P': 14, 'S': 15, 'T': 16,\n 'W': 17, 'Y': 18, 'V': 19, 'B': 20, 'Z': 21, 'X': 22, '*': 23\n};\nconst defaultArgs = {\n gapOpen: 8,\n gapExtend: 2,\n scoringMatrix: BLOSUM62,\n alphabetIndexes: ProtIndexes\n};\n/** Returns a function that calculates the distance between two sequences based on gap penalty and matrix\n * @param {Partial<NeedlemanWunchArgs>}args - arguments for Needleman-Wunch algorithm like gap penalty, Scoring matrix..\n * @return {mmDistanceFunctionType} - function that calculates the distance between two sequences\n*/\nexport function needlemanWunch(args) {\n return (seq1, seq2) => {\n const { gapOpen, gapExtend, scoringMatrix, alphabetIndexes } = { ...defaultArgs, ...args };\n // As we don't need traceback, no need to store the whole matrix\n // Intead, we will store only the last two rows\n const matrix = [\n new Array(seq1.length + 1).fill(0),\n new Array(seq1.length + 1).fill(0)\n ];\n // similarly, we need to keep track of what operation led to the current cell\n // i.e. whether we came from the left, top or diagonal to assign gap open/gap extend penalty\n const verticalGaps = new Array(seq1.length + 1).fill(false);\n const horizontalGaps = new Array(seq1.length + 1).fill(false);\n //variables to keep track which row we are in\n // they will swap places on each iteration\n let prevRow = 0;\n let currRow = 1;\n // Initialize first row\n for (let i = 1; i < seq1.length + 1; i++)\n matrix[0][i] = -gapOpen - (i - 1) * gapExtend;\n // Calculate the rest of the matrix\n for (let i = 1; i < seq2.length + 1; i++) {\n matrix[currRow][0] = -gapOpen - (i - 1) * gapExtend;\n for (let j = 1; j < seq1.length + 1; j++) {\n const diagonal = matrix[prevRow][j - 1] + scoringMatrix[alphabetIndexes[seq1[j - 1]]][alphabetIndexes[seq2[i - 1]]];\n const top = matrix[prevRow][j] - (verticalGaps[j] ? gapExtend : gapOpen);\n const left = matrix[currRow][j - 1] - (horizontalGaps[j - 1] ? gapExtend : gapOpen);\n matrix[currRow][j] = Math.max(diagonal, left, top);\n // update gap arrays\n if (matrix[currRow][j] === diagonal) {\n verticalGaps[j] = false;\n horizontalGaps[j] = false;\n }\n else if (matrix[currRow][j] === left) {\n verticalGaps[j] = false;\n horizontalGaps[j] = true;\n }\n else {\n verticalGaps[j] = true;\n horizontalGaps[j] = false;\n }\n }\n // Swap rows\n prevRow = currRow;\n currRow = (currRow + 1) % 2;\n }\n // as the matrix is the similarity matrix, but we are interested in distance,\n // we need compare it to perfect match score to get reasonable distance\n const perfectMatchSeq1 = seq1.split('').map((c) => scoringMatrix[alphabetIndexes[c]][alphabetIndexes[c]])\n .reduce((a, b) => a + b, 0);\n const perfectMatchSeq2 = seq2.split('').map((c) => scoringMatrix[alphabetIndexes[c]][alphabetIndexes[c]])\n .reduce((a, b) => a + b, 0);\n const maxScore = Math.max(perfectMatchSeq1, perfectMatchSeq2);\n return (maxScore - matrix[prevRow][seq1.length]) / maxScore;\n };\n}\n//# sourceMappingURL=data:application/json;base64,{"version":3,"file":"needleman-wunsch.js","sourceRoot":"","sources":["needleman-wunsch.ts"],"names":[],"mappings":"AAEA,yCAAyC;AACzC,MAAM,QAAQ,GACd,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,CAAC;IACxF,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IACzF,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IACpF,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IACzF,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC9F,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IACrF,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IACtF,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC5F,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IACxF,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC3F,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC3F,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IACxF,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC1F,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC1F,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC/F,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,CAAC;IACpF,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,CAAC;IAC1F,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,EAAE,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC9F,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC5F,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC1F,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IACvF,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IACtF,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC7F,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,CAAC;AAEnG,oCAAoC;AACpC,MAAM,WAAW,GAAyB;IACxC,GAAG,EAAE,CAAC,EAAE,GAAG,EAAE,CAAC,EAAE,GAAG,EAAE,CAAC,EAAE,GAAG,EAAE,CAAC,EAAE,GAAG,EAAE,CAAC,EAAE,GAAG,EAAE,CAAC,EAAE,GAAG,EAAE,CAAC,EAAE,GAAG,EAAE,CAAC,EAAE,GAAG,EAAE,CAAC;IACtE,GAAG,EAAE,CAAC,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE;IACrE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE;CAC9D,CAAC;AAOF,MAAM,WAAW,GAAuB;IACtC,OAAO,EAAE,CAAC;IACV,SAAS,EAAE,CAAC;IACZ,aAAa,EAAE,QAAQ;IACvB,eAAe,EAAE,WAAW;CAC7B,CAAC;AAEF;;;EAGE;AACF,MAAM,UAAU,cAAc,CAAC,IAAiC;IAC9D,OAAO,CAAC,IAAY,EAAE,IAAY,EAAW,EAAE;QAC7C,MAAM,EAAC,OAAO,EAAE,SAAS,EAAE,aAAa,EAAE,eAAe,EAAC,GAAG,EAAC,GAAG,WAAW,EAAE,GAAG,IAAI,EAAC,CAAC;QACvF,gEAAgE;QAChE,+CAA+C;QAC/C,MAAM,MAAM,GAAe;YACzB,IAAI,KAAK,CAAS,IAAI,CAAC,MAAM,GAAG,CAAC,CAAC,CAAC,IAAI,CAAC,CAAC,CAAC;YAC1C,IAAI,KAAK,CAAS,IAAI,CAAC,MAAM,GAAG,CAAC,CAAC,CAAC,IAAI,CAAC,CAAC,CAAC;SAC3C,CAAC;QACF,6EAA6E;QAC7E,4FAA4F;QAC5F,MAAM,YAAY,GAAc,IAAI,KAAK,CAAU,IAAI,CAAC,MAAM,GAAG,CAAC,CAAC,CAAC,IAAI,CAAC,KAAK,CAAC,CAAC;QAChF,MAAM,cAAc,GAAc,IAAI,KAAK,CAAU,IAAI,CAAC,MAAM,GAAG,CAAC,CAAC,CAAC,IAAI,CAAC,KAAK,CAAC,CAAC;QAElF,6CAA6C;QAC7C,0CAA0C;QAC1C,IAAI,OAAO,GAAG,CAAC,CAAC;QAChB,IAAI,OAAO,GAAG,CAAC,CAAC;QAChB,uBAAuB;QACvB,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,GAAG,IAAI,CAAC,MAAM,GAAG,CAAC,EAAE,CAAC,EAAE;YACtC,MAAM,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,GAAG,CAAC,OAAO,GAAG,CAAC,CAAC,GAAG,CAAC,CAAC,GAAG,SAAS,CAAC;QAEhD,mCAAmC;QACnC,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,GAAG,IAAI,CAAC,MAAM,GAAG,CAAC,EAAE,CAAC,EAAE,EAAE;YACxC,MAAM,CAAC,OAAO,CAAC,CAAC,CAAC,CAAC,GAAG,CAAC,OAAO,GAAG,CAAC,CAAC,GAAG,CAAC,CAAC,GAAG,SAAS,CAAC;YACpD,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,GAAG,IAAI,CAAC,MAAM,GAAG,CAAC,EAAE,CAAC,EAAE,EAAE;gBACxC,MAAM,QAAQ,GACZ,MAAM,CAAC,OAAO,CAAC,CAAC,CAAC,GAAG,CAAC,CAAC,GAAG,aAAa,CAAC,eAAe,CAAC,IAAI,CAAC,CAAC,GAAG,CAAC,CAAC,CAAC,CAAC,CAAC,eAAe,CAAC,IAAI,CAAC,CAAC,GAAG,CAAC,CAAC,CAAC,CAAC,CAAC;gBACrG,MAAM,GAAG,GAAG,MAAM,CAAC,OAAO,CAAC,CAAC,CAAC,CAAC,GAAG,CAAC,YAAY,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,SAAS,CAAC,CAAC,CAAC,OAAO,CAAE,CAAC;gBAC1E,MAAM,IAAI,GAAG,MAAM,CAAC,OAAO,CAAC,CAAC,CAAC,GAAG,CAAC,CAAC,GAAG,CAAC,cAAc,CAAC,CAAC,GAAG,CAAC,CAAC,CAAC,CAAC,CAAC,SAAS,CAAC,CAAC,CAAC,OAAO,CAAC,CAAC;gBACpF,MAAM,CAAC,OAAO,CAAC,CAAC,CAAC,CAAC,GAAG,IAAI,CAAC,GAAG,CAC3B,QAAQ,EAAE,IAAI,EAAE,GAAG,CACpB,CAAC;gBACF,oBAAoB;gBACpB,IAAI,MAAM,CAAC,OAAO,CAAC,CAAC,CAAC,CAAC,KAAK,QAAQ,EAAE;oBACnC,YAAY,CAAC,CAAC,CAAC,GAAG,KAAK,CAAC;oBACxB,cAAc,CAAC,CAAC,CAAC,GAAG,KAAK,CAAC;iBAC3B;qBAAM,IAAI,MAAM,CAAC,OAAO,CAAC,CAAC,CAAC,CAAC,KAAK,IAAI,EAAE;oBACtC,YAAY,CAAC,CAAC,CAAC,GAAG,KAAK,CAAC;oBACxB,cAAc,CAAC,CAAC,CAAC,GAAG,IAAI,CAAC;iBAC1B;qBAAM;oBACL,YAAY,CAAC,CAAC,CAAC,GAAG,IAAI,CAAC;oBACvB,cAAc,CAAC,CAAC,CAAC,GAAG,KAAK,CAAC;iBAC3B;aACF;YACD,YAAY;YACZ,OAAO,GAAG,OAAO,CAAC;YAClB,OAAO,GAAG,CAAC,OAAO,GAAG,CAAC,CAAC,GAAG,CAAC,CAAC;SAC7B;QACD,6EAA6E;QAC7E,uEAAuE;QACvE,MAAM,gBAAgB,GAAG,IAAI,CAAC,KAAK,CAAC,EAAE,CAAC,CAAC,GAAG,CAAC,CAAC,CAAC,EAAE,EAAE,CAAC,aAAa,CAAC,eAAe,CAAC,CAAC,CAAC,CAAC,CAAC,eAAe,CAAC,CAAC,CAAC,CAAC,CAAC;aACtG,MAAM,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,EAAE,CAAC,CAAC,GAAG,CAAC,EAAE,CAAC,CAAC,CAAC;QAC9B,MAAM,gBAAgB,GAAG,IAAI,CAAC,KAAK,CAAC,EAAE,CAAC,CAAC,GAAG,CAAC,CAAC,CAAC,EAAE,EAAE,CAAC,aAAa,CAAC,eAAe,CAAC,CAAC,CAAC,CAAC,CAAC,eAAe,CAAC,CAAC,CAAC,CAAC,CAAC;aACtG,MAAM,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,EAAE,CAAC,CAAC,GAAG,CAAC,EAAE,CAAC,CAAC,CAAC;QAC9B,MAAM,QAAQ,GAAG,IAAI,CAAC,GAAG,CAAC,gBAAgB,EAAE,gBAAgB,CAAC,CAAC;QAC9D,OAAO,CAAC,QAAQ,GAAG,MAAM,CAAC,OAAO,CAAC,CAAC,IAAI,CAAC,MAAM,CAAC,CAAC,GAAG,QAAQ,CAAC;IAC9D,CAAC,CAAC;AACJ,CAAC","sourcesContent":["import {mmDistanceFunctionArgs, mmDistanceFunctionType} from './types';\n\n// Blosum 62 matrix for protein sequences\nconst BLOSUM62:Array<Array<number>> =\n[[4, -1, -2, -2, 0, -1, -1, 0, -2, -1, -1, -1, -1, -2, -1, 1, 0, -3, -2, 0, -2, -1, 0, -4],\n  [-1, 5, 0, -2, -3, 1, 0, -2, 0, -3, -2, 2, -1, -3, -2, -1, -1, -3, -2, -3, -1, 0, -1, -4],\n  [-2, 0, 6, 1, -3, 0, 0, 0, 1, -3, -3, 0, -2, -3, -2, 1, 0, -4, -2, -3, 3, 0, -1, -4],\n  [-2, -2, 1, 6, -3, 0, 2, -1, -1, -3, -4, -1, -3, -3, -1, 0, -1, -4, -3, -3, 4, 1, -1, -4],\n  [0, -3, -3, -3, 9, -3, -4, -3, -3, -1, -1, -3, -1, -2, -3, -1, -1, -2, -2, -1, -3, -3, -2, -4],\n  [-1, 1, 0, 0, -3, 5, 2, -2, 0, -3, -2, 1, 0, -3, -1, 0, -1, -2, -1, -2, 0, 3, -1, -4],\n  [-1, 0, 0, 2, -4, 2, 5, -2, 0, -3, -3, 1, -2, -3, -1, 0, -1, -3, -2, -2, 1, 4, -1, -4],\n  [0, -2, 0, -1, -3, -2, -2, 6, -2, -4, -4, -2, -3, -3, -2, 0, -2, -2, -3, -3, -1, -2, -1, -4],\n  [-2, 0, 1, -1, -3, 0, 0, -2, 8, -3, -3, -1, -2, -1, -2, -1, -2, -2, 2, -3, 0, 0, -1, -4],\n  [-1, -3, -3, -3, -1, -3, -3, -4, -3, 4, 2, -3, 1, 0, -3, -2, -1, -3, -1, 3, -3, -3, -1, -4],\n  [-1, -2, -3, -4, -1, -2, -3, -4, -3, 2, 4, -2, 2, 0, -3, -2, -1, -2, -1, 1, -4, -3, -1, -4],\n  [-1, 2, 0, -1, -3, 1, 1, -2, -1, -3, -2, 5, -1, -3, -1, 0, -1, -3, -2, -2, 0, 1, -1, -4],\n  [-1, -1, -2, -3, -1, 0, -2, -3, -2, 1, 2, -1, 5, 0, -2, -1, -1, -1, -1, 1, -3, -1, -1, -4],\n  [-2, -3, -3, -3, -2, -3, -3, -3, -1, 0, 0, -3, 0, 6, -4, -2, -2, 1, 3, -1, -3, -3, -1, -4],\n  [-1, -2, -2, -1, -3, -1, -1, -2, -2, -3, -3, -1, -2, -4, 7, -1, -1, -4, -3, -2, -2, -1, -2, -4],\n  [1, -1, 1, 0, -1, 0, 0, 0, -1, -2, -2, 0, -1, -2, -1, 4, 1, -3, -2, -2, 0, 0, 0, -4],\n  [0, -1, 0, -1, -1, -1, -1, -2, -2, -1, -1, -1, -1, -2, -1, 1, 5, -2, -2, 0, -1, -1, 0, -4],\n  [-3, -3, -4, -4, -2, -2, -3, -2, -2, -3, -2, -3, -1, 1, -4, -3, -2, 11, 2, -3, -4, -3, -2, -4],\n  [-2, -2, -2, -3, -2, -1, -2, -3, 2, -1, -1, -2, -1, 3, -3, -2, -2, 2, 7, -1, -3, -2, -1, -4],\n  [0, -3, -3, -3, -1, -2, -2, -3, -3, 3, 1, -2, 1, -1, -2, -2, 0, -3, -1, 4, -3, -2, -1, -4],\n  [-2, -1, 3, 4, -3, 0, 1, -1, 0, -3, -4, 0, -3, -3, -2, 0, -1, -4, -3, -3, 4, 1, -1, -4],\n  [-1, 0, 0, 1, -3, 3, 4, -2, 0, -3, -3, 1, -1, -3, -1, 0, -1, -3, -2, -2, 1, 4, -1, -4],\n  [0, -1, -1, -1, -2, -1, -1, -1, -1, -1, -1, -1, -1, -1, -2, 0, 0, -2, -1, -1, -1, -1, -1, -4],\n  [-4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, 1]];\n\n// Protein indexes for BLOSUM matrix\nconst ProtIndexes: {[id:string]:number} = {\n  'A': 0, 'R': 1, 'N': 2, 'D': 3, 'C': 4, 'Q': 5, 'E': 6, 'G': 7, 'H': 8,\n  'I': 9, 'L': 10, 'K': 11, 'M': 12, 'F': 13, 'P': 14, 'S': 15, 'T': 16,\n  'W': 17, 'Y': 18, 'V': 19, 'B': 20, 'Z': 21, 'X': 22, '*': 23\n};\n\ntype NeedlemanWunchArgs = mmDistanceFunctionArgs & {\n  gapOpen: number;\n  gapExtend: number;\n}\n\nconst defaultArgs: NeedlemanWunchArgs = {\n  gapOpen: 8,\n  gapExtend: 2,\n  scoringMatrix: BLOSUM62,\n  alphabetIndexes: ProtIndexes\n};\n\n/** Returns a function that calculates the distance between two sequences based on gap penalty and matrix\n * @param {Partial<NeedlemanWunchArgs>}args - arguments for Needleman-Wunch algorithm like gap penalty, Scoring matrix..\n * @return {mmDistanceFunctionType} - function that calculates the distance between two sequences\n*/\nexport function needlemanWunch(args: Partial<NeedlemanWunchArgs>): mmDistanceFunctionType {\n  return (seq1: string, seq2: string) : number => {\n    const {gapOpen, gapExtend, scoringMatrix, alphabetIndexes} = {...defaultArgs, ...args};\n    // As we don't need traceback, no need to store the whole matrix\n    // Intead, we will store only the last two rows\n    const matrix: number[][] = [\n      new Array<number>(seq1.length + 1).fill(0),\n      new Array<number>(seq1.length + 1).fill(0)\n    ];\n    // similarly, we need to keep track of what operation led to the current cell\n    // i.e. whether we came from the left, top or diagonal to assign gap open/gap extend penalty\n    const verticalGaps: boolean[] = new Array<boolean>(seq1.length + 1).fill(false);\n    const horizontalGaps: boolean[] = new Array<boolean>(seq1.length + 1).fill(false);\n\n    //variables to keep track which row we are in\n    // they will swap places on each iteration\n    let prevRow = 0;\n    let currRow = 1;\n    // Initialize first row\n    for (let i = 1; i < seq1.length + 1; i++)\n      matrix[0][i] = -gapOpen - (i - 1) * gapExtend;\n\n    // Calculate the rest of the matrix\n    for (let i = 1; i < seq2.length + 1; i++) {\n      matrix[currRow][0] = -gapOpen - (i - 1) * gapExtend;\n      for (let j = 1; j < seq1.length + 1; j++) {\n        const diagonal =\n          matrix[prevRow][j - 1] + scoringMatrix[alphabetIndexes[seq1[j - 1]]][alphabetIndexes[seq2[i - 1]]];\n        const top = matrix[prevRow][j] - (verticalGaps[j] ? gapExtend : gapOpen );\n        const left = matrix[currRow][j - 1] - (horizontalGaps[j - 1] ? gapExtend : gapOpen);\n        matrix[currRow][j] = Math.max(\n          diagonal, left, top\n        );\n        // update gap arrays\n        if (matrix[currRow][j] === diagonal) {\n          verticalGaps[j] = false;\n          horizontalGaps[j] = false;\n        } else if (matrix[currRow][j] === left) {\n          verticalGaps[j] = false;\n          horizontalGaps[j] = true;\n        } else {\n          verticalGaps[j] = true;\n          horizontalGaps[j] = false;\n        }\n      }\n      // Swap rows\n      prevRow = currRow;\n      currRow = (currRow + 1) % 2;\n    }\n    // as the matrix is the similarity matrix, but we are interested in distance,\n    // we need compare it to perfect match score to get reasonable distance\n    const perfectMatchSeq1 = seq1.split('').map((c) => scoringMatrix[alphabetIndexes[c]][alphabetIndexes[c]])\n      .reduce((a, b) => a + b, 0);\n    const perfectMatchSeq2 = seq2.split('').map((c) => scoringMatrix[alphabetIndexes[c]][alphabetIndexes[c]])\n      .reduce((a, b) => a + b, 0);\n    const maxScore = Math.max(perfectMatchSeq1, perfectMatchSeq2);\n    return (maxScore - matrix[prevRow][seq1.length]) / maxScore;\n  };\n}\n"]}","const peq = new Uint32Array(0x10000);\nconst myers_32 = (a, b) => {\n const n = a.length;\n const m = b.length;\n const lst = 1 << (n - 1);\n let pv = -1;\n let mv = 0;\n let sc = n;\n let i = n;\n while (i--) {\n peq[a.charCodeAt(i)] |= 1 << i;\n }\n for (i = 0; i < m; i++) {\n let eq = peq[b.charCodeAt(i)];\n const xv = eq | mv;\n eq |= ((eq & pv) + pv) ^ pv;\n mv |= ~(eq | pv);\n pv &= eq;\n if (mv & lst) {\n sc++;\n }\n if (pv & lst) {\n sc--;\n }\n mv = (mv << 1) | 1;\n pv = (pv << 1) | ~(xv | mv);\n mv &= xv;\n }\n i = n;\n while (i--) {\n peq[a.charCodeAt(i)] = 0;\n }\n return sc;\n};\nconst myers_x = (b, a) => {\n const n = a.length;\n const m = b.length;\n const mhc = [];\n const phc = [];\n const hsize = Math.ceil(n / 32);\n const vsize = Math.ceil(m / 32);\n for (let i = 0; i < hsize; i++) {\n phc[i] = -1;\n mhc[i] = 0;\n }\n let j = 0;\n for (; j < vsize - 1; j++) {\n let mv = 0;\n let pv = -1;\n const start = j * 32;\n const vlen = Math.min(32, m) + start;\n for (let k = start; k < vlen; k++) {\n peq[b.charCodeAt(k)] |= 1 << k;\n }\n for (let i = 0; i < n; i++) {\n const eq = peq[a.charCodeAt(i)];\n const pb = (phc[(i / 32) | 0] >>> i) & 1;\n const mb = (mhc[(i / 32) | 0] >>> i) & 1;\n const xv = eq | mv;\n const xh = ((((eq | mb) & pv) + pv) ^ pv) | eq | mb;\n let ph = mv | ~(xh | pv);\n let mh = pv & xh;\n if ((ph >>> 31) ^ pb) {\n phc[(i / 32) | 0] ^= 1 << i;\n }\n if ((mh >>> 31) ^ mb) {\n mhc[(i / 32) | 0] ^= 1 << i;\n }\n ph = (ph << 1) | pb;\n mh = (mh << 1) | mb;\n pv = mh | ~(xv | ph);\n mv = ph & xv;\n }\n for (let k = start; k < vlen; k++) {\n peq[b.charCodeAt(k)] = 0;\n }\n }\n let mv = 0;\n let pv = -1;\n const start = j * 32;\n const vlen = Math.min(32, m - start) + start;\n for (let k = start; k < vlen; k++) {\n peq[b.charCodeAt(k)] |= 1 << k;\n }\n let score = m;\n for (let i = 0; i < n; i++) {\n const eq = peq[a.charCodeAt(i)];\n const pb = (phc[(i / 32) | 0] >>> i) & 1;\n const mb = (mhc[(i / 32) | 0] >>> i) & 1;\n const xv = eq | mv;\n const xh = ((((eq | mb) & pv) + pv) ^ pv) | eq | mb;\n let ph = mv | ~(xh | pv);\n let mh = pv & xh;\n score += (ph >>> (m - 1)) & 1;\n score -= (mh >>> (m - 1)) & 1;\n if ((ph >>> 31) ^ pb) {\n phc[(i / 32) | 0] ^= 1 << i;\n }\n if ((mh >>> 31) ^ mb) {\n mhc[(i / 32) | 0] ^= 1 << i;\n }\n ph = (ph << 1) | pb;\n mh = (mh << 1) | mb;\n pv = mh | ~(xv | ph);\n mv = ph & xv;\n }\n for (let k = start; k < vlen; k++) {\n peq[b.charCodeAt(k)] = 0;\n }\n return score;\n};\nconst distance = (a, b) => {\n if (a.length < b.length) {\n const tmp = b;\n b = a;\n a = tmp;\n }\n if (b.length === 0) {\n return a.length;\n }\n if (a.length <= 32) {\n return myers_32(a, b);\n }\n return myers_x(a, b);\n};\nconst closest = (str, arr) => {\n let min_distance = Infinity;\n let min_index = 0;\n for (let i = 0; i < arr.length; i++) {\n const dist = distance(str, arr[i]);\n if (dist < min_distance) {\n min_distance = dist;\n min_index = i;\n }\n }\n return arr[min_index];\n};\nexport { closest, distance };\n"],"names":["isNil","x","hamming","args","distanceF","scoringMatrix","alphabetIndexes","a","b","length","Object","keys","Error","indexes","matrix","minCharCode","Math","min","map","k","charCodeAt","scorringArray","Float32Array","entries","forEach","key","index","matrixRow","key2","index2","getDistanceF","threshold","seq1","seq2","diff","s1l","s2l","thresholdLimit","max","abs","result","i","levenstein","defaultArgs","gapOpen","gapExtend","needlemanWunch","Array","fill","verticalGaps","horizontalGaps","prevRow","currRow","j","diagonal","top","left","perfectMatchSeq1","split","c","reduce","perfectMatchSeq2","maxScore","peq","Uint32Array","distance","tmp","n","m","lst","pv","mv","sc","eq","xv","myers_32","mhc","phc","hsize","ceil","vsize","start","vlen","pb","mb","xh","ph","mh","score","myers_x"],"sourceRoot":""}
1
+ {"version":3,"file":"1.js","mappings":"wGAAO,MAAMA,EAASC,GAAMA,O,gBCArB,SAASC,EAAQC,EAAO,CAAC,GA0B5B,MAAMC,EAzBN,WACI,IAAKD,IAASA,EAAKE,gBAAkBF,EAAKG,gBACtC,MAAO,CAACC,EAAGC,IAAMD,IAAMC,EAAI,EAAI,EACnC,GAAIL,EAAKE,cAAcI,SAAWC,OAAOC,KAAKR,EAAKG,iBAAiBG,OAChE,MAAM,IAAIG,MAAM,mEACpB,MAAMC,EAAUV,EAAKG,gBACfQ,EAASX,EAAKE,cAGdU,EAAcC,KAAKC,OAAOP,OAAOC,KAAKE,GAASK,KAAIC,GAAKA,EAAEC,WAAW,MAAO,EAC5EC,EAAgB,IAAIC,cAAcR,EAAOL,OAASM,IAAgBD,EAAOL,OAASM,IAWxF,OAVAL,OAAOa,QAAQV,GAASW,SAAQ,EAAEC,EAAKC,MAGnC,MAAMC,EAAYb,EAAOY,GACzBhB,OAAOa,QAAQV,GAASW,SAAQ,EAAEI,EAAMC,MAEpCR,EAAcI,EAAIL,WAAW,GAAKN,EAAOL,OAASmB,EAAKR,WAAW,IAAMO,EAAUE,EAAO,GAE3F,IAEC,CAACtB,EAAGC,IACAa,EAAcd,EAAEa,WAAW,GAAKN,EAAOL,OAASD,EAAEY,WAAW,GAE5E,CACkBU,GACZC,EAAY5B,GAAM4B,WAAa,EACrC,MAAO,CAACC,EAAMC,KAGV,IAAIC,EAAO,EACX,MAAMC,EAAMH,EAAKvB,OACX2B,EAAMH,EAAKxB,OACX4B,EAAiBrB,KAAKsB,IAAIH,EAAKC,IAAQ,EAAIL,GAC7CI,IAAQC,IACRF,EAAOlB,KAAKuB,IAAIJ,EAAMC,IAC1B,IAAII,EAAS,EACb,IAAK,IAAIC,EAAI,EAAGA,EAAIzB,KAAKC,IAAIkB,EAAKC,GAAMK,IACpC,GAAIT,EAAKS,KAAOR,EAAKQ,KACjBD,GAAUpC,EAAU4B,EAAKS,GAAIR,EAAKQ,IAC9BD,EAASH,GACT,OAAO,EAKnB,OAFAG,GAAUN,EACVM,GAAUxB,KAAKsB,IAAIH,EAAKC,GACjBI,CAAM,CAErB,C,+DChDO,SAASE,IACZ,MAAO,CAACV,EAAMC,KACH,OAASD,EAAMC,GAAQjB,KAAKsB,IAAIN,EAAKvB,OAAQwB,EAAKxB,OAEjE,C,kCCJA,MA8BMkC,EAAc,CAChBC,QAAS,EACTC,UAAW,GACXxC,cAjCa,CAAC,CAAC,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,EAAG,GAAI,GAAI,EAAG,GAAI,GACrG,EAAE,EAAG,EAAG,GAAI,GAAI,EAAG,EAAG,GAAI,EAAG,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GACvF,EAAE,EAAG,EAAG,EAAG,GAAI,EAAG,EAAG,EAAG,EAAG,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GAClF,EAAE,GAAI,EAAG,EAAG,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GACvF,CAAC,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAC5F,EAAE,EAAG,EAAG,EAAG,GAAI,EAAG,EAAG,GAAI,EAAG,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GACnF,EAAE,EAAG,EAAG,EAAG,GAAI,EAAG,EAAG,GAAI,EAAG,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GACpF,CAAC,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAC1F,EAAE,EAAG,EAAG,GAAI,GAAI,EAAG,EAAG,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,EAAG,EAAG,GAAI,GAAI,GACtF,EAAE,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GACzF,EAAE,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GACzF,EAAE,EAAG,EAAG,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GACtF,EAAE,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GACxF,EAAE,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GACxF,EAAE,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAC7F,CAAC,GAAI,EAAG,EAAG,GAAI,EAAG,EAAG,EAAG,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,EAAG,EAAG,EAAG,GAAI,GAClF,CAAC,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,EAAG,GAAI,GAAI,EAAG,GAAI,GACxF,EAAE,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAC5F,EAAE,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAC1F,CAAC,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,EAAG,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,GACxF,EAAE,GAAI,EAAG,EAAG,GAAI,EAAG,EAAG,GAAI,EAAG,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GACrF,EAAE,EAAG,EAAG,EAAG,GAAI,EAAG,EAAG,GAAI,EAAG,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,EAAG,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GACpF,CAAC,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,EAAG,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAC3F,EAAE,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,GAAI,EAAG,IAW7FC,gBATgB,CAChB,EAAK,EAAG,EAAK,EAAG,EAAK,EAAG,EAAK,EAAG,EAAK,EAAG,EAAK,EAAG,EAAK,EAAG,EAAK,EAAG,EAAK,EACrE,EAAK,EAAG,EAAK,GAAI,EAAK,GAAI,EAAK,GAAI,EAAK,GAAI,EAAK,GAAI,EAAK,GAAI,EAAK,GACnE,EAAK,GAAI,EAAK,GAAI,EAAK,GAAI,EAAK,GAAI,EAAK,GAAI,EAAK,GAAI,IAAK,KAYxD,SAASwC,EAAe3C,GAC3B,MACM4C,EAAgB,IAAIC,YAAY,QAChC,QAAEJ,EAAO,UAAEC,EAAS,cAAExC,EAAa,gBAAEC,GAAoB,IAAKqC,KAAgBxC,GACpFO,OAAOa,QAAQjB,GAAiBkB,SAAQ,EAAEL,EAAG8B,KAAOF,EAAc5B,EAAEC,WAAW,IAAM6B,IAGrF,MAAMnC,EAAS,CACX,IAAIQ,aAPO,KAQX,IAAIA,aARO,MAUf,MAAO,CAACU,EAAMC,KAGV,MAAMiB,EAAe,IAAIC,MAAMnB,EAAKvB,OAAS,GAAG2C,MAAK,GAC/CC,EAAiB,IAAIF,MAAMnB,EAAKvB,OAAS,GAAG2C,MAAK,GAGvD,IAAIE,EAAU,EACVC,EAAU,EAEd,IAAK,IAAId,EAAI,EAAGA,EAAIT,EAAKvB,OAAS,EAAGgC,IACjC3B,EAAO,GAAG2B,IAAMG,GAAWH,EAAI,GAAKI,EACpC/B,EAAO,GAAG2B,GAAK,EAGnB,IAAK,IAAIA,EAAI,EAAGA,EAAIR,EAAKxB,OAAS,EAAGgC,IAAK,CACtC3B,EAAOyC,GAAS,IAAMX,GAAWH,EAAI,GAAKI,EAC1C,IAAK,IAAIW,EAAI,EAAGA,EAAIxB,EAAKvB,OAAS,EAAG+C,IAAK,CACtC,MAAMC,EAAW3C,EAAOwC,GAASE,EAAI,GAAKnD,EAAc0C,EAAcf,EAAKZ,WAAWoC,EAAI,KAAKT,EAAcd,EAAKb,WAAWqB,EAAI,KAC3HiB,EAAM5C,EAAOwC,GAASE,IAAMN,EAAaM,GAAKX,EAAYD,GAC1De,EAAO7C,EAAOyC,GAASC,EAAI,IAAMH,EAAeG,EAAI,GAAKX,EAAYD,GAC3E9B,EAAOyC,GAASC,GAAKxC,KAAKsB,IAAImB,EAAUE,EAAMD,GAE1C5C,EAAOyC,GAASC,KAAOC,GACvBP,EAAaM,IAAK,EAClBH,EAAeG,IAAK,GAEf1C,EAAOyC,GAASC,KAAOG,GAC5BT,EAAaM,IAAK,EAClBH,EAAeG,IAAK,IAGpBN,EAAaM,IAAK,EAClBH,EAAeG,IAAK,EAE5B,CAEAF,EAAUC,EACVA,GAAWA,EAAU,GAAK,CAC9B,CAQA,MAAMK,EAAW5C,KAAKsB,IAAIN,EAAKvB,OAAQwB,EAAKxB,QAC5C,OAAQmD,EAAW9C,EAAOwC,GAAStB,EAAKvB,SAAWmD,CAAQ,CAEnE,C,kCCtGA,MAAMC,EAAM,IAAIC,YAAY,OA+GtBC,EAAW,CAACxD,EAAGC,KACjB,GAAID,EAAEE,OAASD,EAAEC,OAAQ,CACrB,MAAMuD,EAAMxD,EACZA,EAAID,EACJA,EAAIyD,CACR,CACA,OAAiB,IAAbxD,EAAEC,OACKF,EAAEE,OAETF,EAAEE,QAAU,GAvHH,EAACF,EAAGC,KACjB,MAAMyD,EAAI1D,EAAEE,OACNyD,EAAI1D,EAAEC,OACN0D,EAAM,GAAMF,EAAI,EACtB,IAAIG,GAAM,EACNC,EAAK,EACLC,EAAKL,EACLxB,EAAIwB,EACR,KAAOxB,KACHoB,EAAItD,EAAEa,WAAWqB,KAAO,GAAKA,EAEjC,IAAKA,EAAI,EAAGA,EAAIyB,EAAGzB,IAAK,CACpB,IAAI8B,EAAKV,EAAIrD,EAAEY,WAAWqB,IAC1B,MAAM+B,EAAKD,EAAKF,EAChBE,IAAQA,EAAKH,GAAMA,EAAMA,EACzBC,KAAQE,EAAKH,GACbA,GAAMG,EACFF,EAAKF,GACLG,IAEAF,EAAKD,GACLG,IAEJD,EAAMA,GAAM,EAAK,EACjBD,EAAMA,GAAM,IAAOI,EAAKH,GACxBA,GAAMG,CACV,CAEA,IADA/B,EAAIwB,EACGxB,KACHoB,EAAItD,EAAEa,WAAWqB,IAAM,EAE3B,OAAO6B,CAAE,EAyFEG,CAASlE,EAAGC,GAvFX,EAACA,EAAGD,KAChB,MAAM0D,EAAI1D,EAAEE,OACNyD,EAAI1D,EAAEC,OACNiE,EAAM,GACNC,EAAM,GACNC,EAAQ5D,KAAK6D,KAAKZ,EAAI,IACtBa,EAAQ9D,KAAK6D,KAAKX,EAAI,IAC5B,IAAK,IAAIzB,EAAI,EAAGA,EAAImC,EAAOnC,IACvBkC,EAAIlC,IAAM,EACViC,EAAIjC,GAAK,EAEb,IAAIe,EAAI,EACR,KAAOA,EAAIsB,EAAQ,EAAGtB,IAAK,CACvB,IAAIa,EAAK,EACLD,GAAM,EACV,MAAMW,EAAY,GAAJvB,EACRwB,EAAOhE,KAAKC,IAAI,GAAIiD,GAAKa,EAC/B,IAAK,IAAI5D,EAAI4D,EAAO5D,EAAI6D,EAAM7D,IAC1B0C,EAAIrD,EAAEY,WAAWD,KAAO,GAAKA,EAEjC,IAAK,IAAIsB,EAAI,EAAGA,EAAIwB,EAAGxB,IAAK,CACxB,MAAM8B,EAAKV,EAAItD,EAAEa,WAAWqB,IACtBwC,EAAMN,EAAKlC,EAAI,GAAM,KAAOA,EAAK,EACjCyC,EAAMR,EAAKjC,EAAI,GAAM,KAAOA,EAAK,EACjC+B,EAAKD,EAAKF,EACVc,IAASZ,EAAKW,GAAMd,GAAMA,EAAMA,EAAMG,EAAKW,EACjD,IAAIE,EAAKf,IAAOc,EAAKf,GACjBiB,EAAKjB,EAAKe,EACTC,IAAO,GAAMH,IACdN,EAAKlC,EAAI,GAAM,IAAM,GAAKA,GAEzB4C,IAAO,GAAMH,IACdR,EAAKjC,EAAI,GAAM,IAAM,GAAKA,GAE9B2C,EAAMA,GAAM,EAAKH,EACjBI,EAAMA,GAAM,EAAKH,EACjBd,EAAKiB,IAAOb,EAAKY,GACjBf,EAAKe,EAAKZ,CACd,CACA,IAAK,IAAIrD,EAAI4D,EAAO5D,EAAI6D,EAAM7D,IAC1B0C,EAAIrD,EAAEY,WAAWD,IAAM,CAE/B,CACA,IAAIkD,EAAK,EACLD,GAAM,EACV,MAAMW,EAAY,GAAJvB,EACRwB,EAAOhE,KAAKC,IAAI,GAAIiD,EAAIa,GAASA,EACvC,IAAK,IAAI5D,EAAI4D,EAAO5D,EAAI6D,EAAM7D,IAC1B0C,EAAIrD,EAAEY,WAAWD,KAAO,GAAKA,EAEjC,IAAImE,EAAQpB,EACZ,IAAK,IAAIzB,EAAI,EAAGA,EAAIwB,EAAGxB,IAAK,CACxB,MAAM8B,EAAKV,EAAItD,EAAEa,WAAWqB,IACtBwC,EAAMN,EAAKlC,EAAI,GAAM,KAAOA,EAAK,EACjCyC,EAAMR,EAAKjC,EAAI,GAAM,KAAOA,EAAK,EACjC+B,EAAKD,EAAKF,EACVc,IAASZ,EAAKW,GAAMd,GAAMA,EAAMA,EAAMG,EAAKW,EACjD,IAAIE,EAAKf,IAAOc,EAAKf,GACjBiB,EAAKjB,EAAKe,EACdG,GAAUF,IAAQlB,EAAI,EAAM,EAC5BoB,GAAUD,IAAQnB,EAAI,EAAM,EACvBkB,IAAO,GAAMH,IACdN,EAAKlC,EAAI,GAAM,IAAM,GAAKA,GAEzB4C,IAAO,GAAMH,IACdR,EAAKjC,EAAI,GAAM,IAAM,GAAKA,GAE9B2C,EAAMA,GAAM,EAAKH,EACjBI,EAAMA,GAAM,EAAKH,EACjBd,EAAKiB,IAAOb,EAAKY,GACjBf,EAAKe,EAAKZ,CACd,CACA,IAAK,IAAIrD,EAAI4D,EAAO5D,EAAI6D,EAAM7D,IAC1B0C,EAAIrD,EAAEY,WAAWD,IAAM,EAE3B,OAAOmE,CAAK,EAcLC,CAAQhF,EAAGC,EAAE,C","sources":["webpack://bio/./node_modules/@datagrok-libraries/ml/src/distance-matrix/utils.js","webpack://bio/./node_modules/@datagrok-libraries/ml/src/macromolecule-distance-functions/hamming.js","webpack://bio/./node_modules/@datagrok-libraries/ml/src/macromolecule-distance-functions/levenstein.js","webpack://bio/./node_modules/@datagrok-libraries/ml/src/macromolecule-distance-functions/needleman-wunsch.js","webpack://bio/./node_modules/fastest-levenshtein/esm/mod.js"],"sourcesContent":["export const isNil = (x) => x === null || x === undefined;\n//# sourceMappingURL=data:application/json;base64,eyJ2ZXJzaW9uIjozLCJmaWxlIjoidXRpbHMuanMiLCJzb3VyY2VSb290IjoiIiwic291cmNlcyI6WyJ1dGlscy50cyJdLCJuYW1lcyI6W10sIm1hcHBpbmdzIjoiQUFBQSxNQUFNLENBQUMsTUFBTSxLQUFLLEdBQUcsQ0FBQyxDQUFNLEVBQUUsRUFBRSxDQUFDLENBQUMsS0FBSyxJQUFJLElBQUksQ0FBQyxLQUFLLFNBQVMsQ0FBQyIsInNvdXJjZXNDb250ZW50IjpbImV4cG9ydCBjb25zdCBpc05pbCA9ICh4OiBhbnkpID0+IHggPT09IG51bGwgfHwgeCA9PT0gdW5kZWZpbmVkO1xuIl19","export function hamming(args = {}) {\n function getDistanceF() {\n if (!args || !args.scoringMatrix || !args.alphabetIndexes)\n return (a, b) => a === b ? 0 : 1;\n if (args.scoringMatrix.length !== Object.keys(args.alphabetIndexes).length)\n throw new Error('Scoring matrix and alphabet indexes should have the same length');\n const indexes = args.alphabetIndexes;\n const matrix = args.scoringMatrix;\n //const matrixMap = new Map<string, Map<string, number>>();\n //const map2: any = {};\n const minCharCode = Math.min(...Object.keys(indexes).map(k => k.charCodeAt(0))) + 1;\n const scorringArray = new Float32Array((matrix.length + minCharCode) * (matrix.length + minCharCode));\n Object.entries(indexes).forEach(([key, index]) => {\n //matrixMap.set(key, new Map<string, number>());\n //map2[key] = {};\n const matrixRow = matrix[index];\n Object.entries(indexes).forEach(([key2, index2]) => {\n //matrixMap.get(key)!.set(key2, matrixRow[index2]);\n scorringArray[key.charCodeAt(0) * matrix.length + key2.charCodeAt(0)] = matrixRow[index2];\n //map2[key][key2] = matrixRow[index2];\n });\n });\n return (a, b) => {\n return scorringArray[a.charCodeAt(0) * matrix.length + b.charCodeAt(0)];\n };\n }\n const distanceF = getDistanceF();\n const threshold = args?.threshold ?? 0;\n return (seq1, seq2) => {\n // hamming distance should only be used with same size strings,\n // but still, lets add a check and if they are not same length add the difference to the result\n let diff = 0;\n const s1l = seq1.length;\n const s2l = seq2.length;\n const thresholdLimit = Math.max(s1l, s2l) * (1 - threshold);\n if (s1l !== s2l)\n diff = Math.abs(s1l - s2l);\n let result = 0;\n for (let i = 0; i < Math.min(s1l, s2l); i++) {\n if (seq1[i] !== seq2[i]) {\n result += distanceF(seq1[i], seq2[i]);\n if (result > thresholdLimit)\n return 1;\n }\n }\n result += diff;\n result /= Math.max(s1l, s2l);\n return result;\n };\n}\n//# sourceMappingURL=data:application/json;base64,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","import { distance } from 'fastest-levenshtein';\nexport function levenstein() {\n return (seq1, seq2) => {\n return distance(seq1, seq2) / Math.max(seq1.length, seq2.length);\n };\n}\n//# sourceMappingURL=data:application/json;base64,eyJ2ZXJzaW9uIjozLCJmaWxlIjoibGV2ZW5zdGVpbi5qcyIsInNvdXJjZVJvb3QiOiIiLCJzb3VyY2VzIjpbImxldmVuc3RlaW4udHMiXSwibmFtZXMiOltdLCJtYXBwaW5ncyI6IkFBQUEsT0FBTyxFQUFDLFFBQVEsRUFBQyxNQUFNLHFCQUFxQixDQUFDO0FBRzdDLE1BQU0sVUFBVSxVQUFVO0lBQ3hCLE9BQU8sQ0FBQyxJQUFZLEVBQUUsSUFBWSxFQUFFLEVBQUU7UUFDcEMsT0FBTyxRQUFRLENBQUMsSUFBSSxFQUFFLElBQUksQ0FBQyxHQUFHLElBQUksQ0FBQyxHQUFHLENBQUMsSUFBSSxDQUFDLE1BQU0sRUFBRSxJQUFJLENBQUMsTUFBTSxDQUFDLENBQUM7SUFDbkUsQ0FBQyxDQUFDO0FBQ0osQ0FBQyIsInNvdXJjZXNDb250ZW50IjpbImltcG9ydCB7ZGlzdGFuY2V9IGZyb20gJ2Zhc3Rlc3QtbGV2ZW5zaHRlaW4nO1xuaW1wb3J0IHttbURpc3RhbmNlRnVuY3Rpb25UeXBlfSBmcm9tICcuL3R5cGVzJztcblxuZXhwb3J0IGZ1bmN0aW9uIGxldmVuc3RlaW4oKTogbW1EaXN0YW5jZUZ1bmN0aW9uVHlwZSB7XG4gIHJldHVybiAoc2VxMTogc3RyaW5nLCBzZXEyOiBzdHJpbmcpID0+IHtcbiAgICByZXR1cm4gZGlzdGFuY2Uoc2VxMSwgc2VxMikgLyBNYXRoLm1heChzZXExLmxlbmd0aCwgc2VxMi5sZW5ndGgpO1xuICB9O1xufVxuIl19","// Blosum 62 matrix for protein sequences\nconst BLOSUM62 = [[4, -1, -2, -2, 0, -1, -1, 0, -2, -1, -1, -1, -1, -2, -1, 1, 0, -3, -2, 0, -2, -1, 0, -4],\n [-1, 5, 0, -2, -3, 1, 0, -2, 0, -3, -2, 2, -1, -3, -2, -1, -1, -3, -2, -3, -1, 0, -1, -4],\n [-2, 0, 6, 1, -3, 0, 0, 0, 1, -3, -3, 0, -2, -3, -2, 1, 0, -4, -2, -3, 3, 0, -1, -4],\n [-2, -2, 1, 6, -3, 0, 2, -1, -1, -3, -4, -1, -3, -3, -1, 0, -1, -4, -3, -3, 4, 1, -1, -4],\n [0, -3, -3, -3, 9, -3, -4, -3, -3, -1, -1, -3, -1, -2, -3, -1, -1, -2, -2, -1, -3, -3, -2, -4],\n [-1, 1, 0, 0, -3, 5, 2, -2, 0, -3, -2, 1, 0, -3, -1, 0, -1, -2, -1, -2, 0, 3, -1, -4],\n [-1, 0, 0, 2, -4, 2, 5, -2, 0, -3, -3, 1, -2, -3, -1, 0, -1, -3, -2, -2, 1, 4, -1, -4],\n [0, -2, 0, -1, -3, -2, -2, 6, -2, -4, -4, -2, -3, -3, -2, 0, -2, -2, -3, -3, -1, -2, -1, -4],\n [-2, 0, 1, -1, -3, 0, 0, -2, 8, -3, -3, -1, -2, -1, -2, -1, -2, -2, 2, -3, 0, 0, -1, -4],\n [-1, -3, -3, -3, -1, -3, -3, -4, -3, 4, 2, -3, 1, 0, -3, -2, -1, -3, -1, 3, -3, -3, -1, -4],\n [-1, -2, -3, -4, -1, -2, -3, -4, -3, 2, 4, -2, 2, 0, -3, -2, -1, -2, -1, 1, -4, -3, -1, -4],\n [-1, 2, 0, -1, -3, 1, 1, -2, -1, -3, -2, 5, -1, -3, -1, 0, -1, -3, -2, -2, 0, 1, -1, -4],\n [-1, -1, -2, -3, -1, 0, -2, -3, -2, 1, 2, -1, 5, 0, -2, -1, -1, -1, -1, 1, -3, -1, -1, -4],\n [-2, -3, -3, -3, -2, -3, -3, -3, -1, 0, 0, -3, 0, 6, -4, -2, -2, 1, 3, -1, -3, -3, -1, -4],\n [-1, -2, -2, -1, -3, -1, -1, -2, -2, -3, -3, -1, -2, -4, 7, -1, -1, -4, -3, -2, -2, -1, -2, -4],\n [1, -1, 1, 0, -1, 0, 0, 0, -1, -2, -2, 0, -1, -2, -1, 4, 1, -3, -2, -2, 0, 0, 0, -4],\n [0, -1, 0, -1, -1, -1, -1, -2, -2, -1, -1, -1, -1, -2, -1, 1, 5, -2, -2, 0, -1, -1, 0, -4],\n [-3, -3, -4, -4, -2, -2, -3, -2, -2, -3, -2, -3, -1, 1, -4, -3, -2, 11, 2, -3, -4, -3, -2, -4],\n [-2, -2, -2, -3, -2, -1, -2, -3, 2, -1, -1, -2, -1, 3, -3, -2, -2, 2, 7, -1, -3, -2, -1, -4],\n [0, -3, -3, -3, -1, -2, -2, -3, -3, 3, 1, -2, 1, -1, -2, -2, 0, -3, -1, 4, -3, -2, -1, -4],\n [-2, -1, 3, 4, -3, 0, 1, -1, 0, -3, -4, 0, -3, -3, -2, 0, -1, -4, -3, -3, 4, 1, -1, -4],\n [-1, 0, 0, 1, -3, 3, 4, -2, 0, -3, -3, 1, -1, -3, -1, 0, -1, -3, -2, -2, 1, 4, -1, -4],\n [0, -1, -1, -1, -2, -1, -1, -1, -1, -1, -1, -1, -1, -1, -2, 0, 0, -2, -1, -1, -1, -1, -1, -4],\n [-4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, 1]];\n// Protein indexes for BLOSUM matrix\nconst ProtIndexes = {\n 'A': 0, 'R': 1, 'N': 2, 'D': 3, 'C': 4, 'Q': 5, 'E': 6, 'G': 7, 'H': 8,\n 'I': 9, 'L': 10, 'K': 11, 'M': 12, 'F': 13, 'P': 14, 'S': 15, 'T': 16,\n 'W': 17, 'Y': 18, 'V': 19, 'B': 20, 'Z': 21, 'X': 22, '*': 23\n};\nconst defaultArgs = {\n gapOpen: 1,\n gapExtend: 0.6,\n scoringMatrix: BLOSUM62,\n alphabetIndexes: ProtIndexes\n};\n/** Returns a function that calculates the distance between two sequences based on gap penalty and matrix\n * @param {Partial<NeedlemanWunchArgs>}args - arguments for Needleman-Wunch algorithm like gap penalty, Scoring matrix..\n * @return {mmDistanceFunctionType} - function that calculates the distance between two sequences\n*/\nexport function needlemanWunch(args) {\n const maxLen = 10000;\n const charCodeArray = new Uint16Array(0x10000);\n const { gapOpen, gapExtend, scoringMatrix, alphabetIndexes } = { ...defaultArgs, ...args };\n Object.entries(alphabetIndexes).forEach(([k, v]) => charCodeArray[k.charCodeAt(0)] = v);\n // As we don't need traceback, no need to store the whole matrix\n // Intead, we will store only the last two rows\n const matrix = [\n new Float32Array(maxLen),\n new Float32Array(maxLen)\n ];\n return (seq1, seq2) => {\n // similarly, we need to keep track of what operation led to the current cell\n // i.e. whether we came from the left, top or diagonal to assign gap open/gap extend penalty\n const verticalGaps = new Array(seq1.length + 1).fill(false);\n const horizontalGaps = new Array(seq1.length + 1).fill(false);\n //variables to keep track which row we are in\n // they will swap places on each iteration\n let prevRow = 0;\n let currRow = 1;\n // Initialize first row\n for (let i = 1; i < seq1.length + 1; i++) {\n matrix[0][i] = -gapOpen - (i - 1) * gapExtend;\n matrix[1][i] = 0;\n }\n // Calculate the rest of the matrix\n for (let i = 1; i < seq2.length + 1; i++) {\n matrix[currRow][0] = -gapOpen - (i - 1) * gapExtend;\n for (let j = 1; j < seq1.length + 1; j++) {\n const diagonal = matrix[prevRow][j - 1] + scoringMatrix[charCodeArray[seq1.charCodeAt(j - 1)]][charCodeArray[seq2.charCodeAt(i - 1)]];\n const top = matrix[prevRow][j] - (verticalGaps[j] ? gapExtend : gapOpen);\n const left = matrix[currRow][j - 1] - (horizontalGaps[j - 1] ? gapExtend : gapOpen);\n matrix[currRow][j] = Math.max(diagonal, left, top);\n // update gap arrays\n if (matrix[currRow][j] === diagonal) {\n verticalGaps[j] = false;\n horizontalGaps[j] = false;\n }\n else if (matrix[currRow][j] === left) {\n verticalGaps[j] = false;\n horizontalGaps[j] = true;\n }\n else {\n verticalGaps[j] = true;\n horizontalGaps[j] = false;\n }\n }\n // Swap rows\n prevRow = currRow;\n currRow = (currRow + 1) % 2;\n }\n // as the matrix is the similarity matrix, but we are interested in distance,\n // we need compare it to perfect match score to get reasonable distance\n // const perfectMatchSeq1 = seq1.split('').map((c) => scoringMatrix[alphabetIndexes[c]][alphabetIndexes[c]])\n // .reduce((a, b) => a + b, 0);\n // const perfectMatchSeq2 = seq2.split('').map((c) => scoringMatrix[alphabetIndexes[c]][alphabetIndexes[c]])\n // .reduce((a, b) => a + b, 0);\n // const maxScore = Math.max(perfectMatchSeq1, perfectMatchSeq2);\n const maxScore = Math.max(seq1.length, seq2.length);\n return (maxScore - matrix[prevRow][seq1.length]) / maxScore;\n };\n}\n//# sourceMappingURL=data:application/json;base64,{"version":3,"file":"needleman-wunsch.js","sourceRoot":"","sources":["needleman-wunsch.ts"],"names":[],"mappings":"AAEA,yCAAyC;AACzC,MAAM,QAAQ,GACd,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,CAAC;IACxF,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IACzF,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IACpF,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IACzF,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC9F,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IACrF,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IACtF,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC5F,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IACxF,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC3F,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC3F,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IACxF,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC1F,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC1F,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC/F,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,CAAC;IACpF,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,CAAC;IAC1F,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,EAAE,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC9F,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC5F,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC1F,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IACvF,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IACtF,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,EAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC;IAC7F,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,CAAC;AAEnG,oCAAoC;AACpC,MAAM,WAAW,GAAyB;IACxC,GAAG,EAAE,CAAC,EAAE,GAAG,EAAE,CAAC,EAAE,GAAG,EAAE,CAAC,EAAE,GAAG,EAAE,CAAC,EAAE,GAAG,EAAE,CAAC,EAAE,GAAG,EAAE,CAAC,EAAE,GAAG,EAAE,CAAC,EAAE,GAAG,EAAE,CAAC,EAAE,GAAG,EAAE,CAAC;IACtE,GAAG,EAAE,CAAC,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE;IACrE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE,EAAE,GAAG,EAAE,EAAE;CAC9D,CAAC;AAOF,MAAM,WAAW,GAAuB;IACtC,OAAO,EAAE,CAAC;IACV,SAAS,EAAE,GAAG;IACd,aAAa,EAAE,QAAQ;IACvB,eAAe,EAAE,WAAW;CAC7B,CAAC;AAEF;;;EAGE;AACF,MAAM,UAAU,cAAc,CAAC,IAAiC;IAC9D,MAAM,MAAM,GAAG,KAAK,CAAC;IACrB,MAAM,aAAa,GAAG,IAAI,WAAW,CAAC,OAAO,CAAC,CAAC;IAE/C,MAAM,EAAC,OAAO,EAAE,SAAS,EAAE,aAAa,EAAE,eAAe,EAAC,GAAG,EAAC,GAAG,WAAW,EAAE,GAAG,IAAI,EAAC,CAAC;IACvF,MAAM,CAAC,OAAO,CAAC,eAAe,CAAC,CAAC,OAAO,CAAC,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,EAAE,CAAC,aAAa,CAAC,CAAC,CAAC,UAAU,CAAC,CAAC,CAAC,CAAC,GAAG,CAAC,CAAC,CAAC;IACxF,gEAAgE;IAChE,+CAA+C;IAC/C,MAAM,MAAM,GAAwB;QAClC,IAAI,YAAY,CAAC,MAAM,CAAC;QACxB,IAAI,YAAY,CAAC,MAAM,CAAC;KACzB,CAAC;IACF,OAAO,CAAC,IAAY,EAAE,IAAY,EAAW,EAAE;QAC7C,6EAA6E;QAC7E,4FAA4F;QAE5F,MAAM,YAAY,GAAc,IAAI,KAAK,CAAU,IAAI,CAAC,MAAM,GAAE,CAAC,CAAC,CAAC,IAAI,CAAC,KAAK,CAAC,CAAC;QAC/E,MAAM,cAAc,GAAc,IAAI,KAAK,CAAU,IAAI,CAAC,MAAM,GAAE,CAAC,CAAC,CAAC,IAAI,CAAC,KAAK,CAAC,CAAC;QACjF,6CAA6C;QAC7C,0CAA0C;QAC1C,IAAI,OAAO,GAAG,CAAC,CAAC;QAChB,IAAI,OAAO,GAAG,CAAC,CAAC;QAChB,uBAAuB;QACvB,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,GAAG,IAAI,CAAC,MAAM,GAAG,CAAC,EAAE,CAAC,EAAE,EAAE;YACxC,MAAM,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,GAAG,CAAC,OAAO,GAAG,CAAC,CAAC,GAAG,CAAC,CAAC,GAAG,SAAS,CAAC;YAC9C,MAAM,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,GAAG,CAAC,CAAC;SAClB;QAED,mCAAmC;QACnC,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,GAAG,IAAI,CAAC,MAAM,GAAG,CAAC,EAAE,CAAC,EAAE,EAAE;YACxC,MAAM,CAAC,OAAO,CAAC,CAAC,CAAC,CAAC,GAAG,CAAC,OAAO,GAAG,CAAC,CAAC,GAAG,CAAC,CAAC,GAAG,SAAS,CAAC;YACpD,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,GAAG,IAAI,CAAC,MAAM,GAAG,CAAC,EAAE,CAAC,EAAE,EAAE;gBACxC,MAAM,QAAQ,GACZ,MAAM,CAAC,OAAO,CAAC,CAAC,CAAC,GAAG,CAAC,CAAC,GAAG,aAAa,CAAC,aAAa,CAAC,IAAI,CAAC,UAAU,CAAC,CAAC,GAAG,CAAC,CAAC,CAAC,CAAC,CAAC,aAAa,CAAC,IAAI,CAAC,UAAU,CAAC,CAAC,GAAG,CAAC,CAAC,CAAC,CAAC,CAAC;gBACvH,MAAM,GAAG,GAAG,MAAM,CAAC,OAAO,CAAC,CAAC,CAAC,CAAC,GAAG,CAAC,YAAY,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,SAAS,CAAC,CAAC,CAAC,OAAO,CAAE,CAAC;gBAC1E,MAAM,IAAI,GAAG,MAAM,CAAC,OAAO,CAAC,CAAC,CAAC,GAAG,CAAC,CAAC,GAAG,CAAC,cAAc,CAAC,CAAC,GAAG,CAAC,CAAC,CAAC,CAAC,CAAC,SAAS,CAAC,CAAC,CAAC,OAAO,CAAC,CAAC;gBACpF,MAAM,CAAC,OAAO,CAAC,CAAC,CAAC,CAAC,GAAG,IAAI,CAAC,GAAG,CAC3B,QAAQ,EAAE,IAAI,EAAE,GAAG,CACpB,CAAC;gBACF,oBAAoB;gBACpB,IAAI,MAAM,CAAC,OAAO,CAAC,CAAC,CAAC,CAAC,KAAK,QAAQ,EAAE;oBACnC,YAAY,CAAC,CAAC,CAAC,GAAG,KAAK,CAAC;oBACxB,cAAc,CAAC,CAAC,CAAC,GAAG,KAAK,CAAC;iBAC3B;qBAAM,IAAI,MAAM,CAAC,OAAO,CAAC,CAAC,CAAC,CAAC,KAAK,IAAI,EAAE;oBACtC,YAAY,CAAC,CAAC,CAAC,GAAG,KAAK,CAAC;oBACxB,cAAc,CAAC,CAAC,CAAC,GAAG,IAAI,CAAC;iBAC1B;qBAAM;oBACL,YAAY,CAAC,CAAC,CAAC,GAAG,IAAI,CAAC;oBACvB,cAAc,CAAC,CAAC,CAAC,GAAG,KAAK,CAAC;iBAC3B;aACF;YACD,YAAY;YACZ,OAAO,GAAG,OAAO,CAAC;YAClB,OAAO,GAAG,CAAC,OAAO,GAAG,CAAC,CAAC,GAAG,CAAC,CAAC;SAC7B;QACD,6EAA6E;QAC7E,uEAAuE;QACvE,4GAA4G;QAC5G,iCAAiC;QACjC,4GAA4G;QAC5G,iCAAiC;QACjC,iEAAiE;QACjE,MAAM,QAAQ,GAAG,IAAI,CAAC,GAAG,CAAC,IAAI,CAAC,MAAM,EAAE,IAAI,CAAC,MAAM,CAAC,CAAC;QACpD,OAAO,CAAC,QAAQ,GAAG,MAAM,CAAC,OAAO,CAAC,CAAC,IAAI,CAAC,MAAM,CAAC,CAAC,GAAG,QAAQ,CAAC;IAC9D,CAAC,CAAC;AACJ,CAAC","sourcesContent":["import {mmDistanceFunctionArgs, mmDistanceFunctionType} from './types';\n\n// Blosum 62 matrix for protein sequences\nconst BLOSUM62:Array<Array<number>> =\n[[4, -1, -2, -2, 0, -1, -1, 0, -2, -1, -1, -1, -1, -2, -1, 1, 0, -3, -2, 0, -2, -1, 0, -4],\n  [-1, 5, 0, -2, -3, 1, 0, -2, 0, -3, -2, 2, -1, -3, -2, -1, -1, -3, -2, -3, -1, 0, -1, -4],\n  [-2, 0, 6, 1, -3, 0, 0, 0, 1, -3, -3, 0, -2, -3, -2, 1, 0, -4, -2, -3, 3, 0, -1, -4],\n  [-2, -2, 1, 6, -3, 0, 2, -1, -1, -3, -4, -1, -3, -3, -1, 0, -1, -4, -3, -3, 4, 1, -1, -4],\n  [0, -3, -3, -3, 9, -3, -4, -3, -3, -1, -1, -3, -1, -2, -3, -1, -1, -2, -2, -1, -3, -3, -2, -4],\n  [-1, 1, 0, 0, -3, 5, 2, -2, 0, -3, -2, 1, 0, -3, -1, 0, -1, -2, -1, -2, 0, 3, -1, -4],\n  [-1, 0, 0, 2, -4, 2, 5, -2, 0, -3, -3, 1, -2, -3, -1, 0, -1, -3, -2, -2, 1, 4, -1, -4],\n  [0, -2, 0, -1, -3, -2, -2, 6, -2, -4, -4, -2, -3, -3, -2, 0, -2, -2, -3, -3, -1, -2, -1, -4],\n  [-2, 0, 1, -1, -3, 0, 0, -2, 8, -3, -3, -1, -2, -1, -2, -1, -2, -2, 2, -3, 0, 0, -1, -4],\n  [-1, -3, -3, -3, -1, -3, -3, -4, -3, 4, 2, -3, 1, 0, -3, -2, -1, -3, -1, 3, -3, -3, -1, -4],\n  [-1, -2, -3, -4, -1, -2, -3, -4, -3, 2, 4, -2, 2, 0, -3, -2, -1, -2, -1, 1, -4, -3, -1, -4],\n  [-1, 2, 0, -1, -3, 1, 1, -2, -1, -3, -2, 5, -1, -3, -1, 0, -1, -3, -2, -2, 0, 1, -1, -4],\n  [-1, -1, -2, -3, -1, 0, -2, -3, -2, 1, 2, -1, 5, 0, -2, -1, -1, -1, -1, 1, -3, -1, -1, -4],\n  [-2, -3, -3, -3, -2, -3, -3, -3, -1, 0, 0, -3, 0, 6, -4, -2, -2, 1, 3, -1, -3, -3, -1, -4],\n  [-1, -2, -2, -1, -3, -1, -1, -2, -2, -3, -3, -1, -2, -4, 7, -1, -1, -4, -3, -2, -2, -1, -2, -4],\n  [1, -1, 1, 0, -1, 0, 0, 0, -1, -2, -2, 0, -1, -2, -1, 4, 1, -3, -2, -2, 0, 0, 0, -4],\n  [0, -1, 0, -1, -1, -1, -1, -2, -2, -1, -1, -1, -1, -2, -1, 1, 5, -2, -2, 0, -1, -1, 0, -4],\n  [-3, -3, -4, -4, -2, -2, -3, -2, -2, -3, -2, -3, -1, 1, -4, -3, -2, 11, 2, -3, -4, -3, -2, -4],\n  [-2, -2, -2, -3, -2, -1, -2, -3, 2, -1, -1, -2, -1, 3, -3, -2, -2, 2, 7, -1, -3, -2, -1, -4],\n  [0, -3, -3, -3, -1, -2, -2, -3, -3, 3, 1, -2, 1, -1, -2, -2, 0, -3, -1, 4, -3, -2, -1, -4],\n  [-2, -1, 3, 4, -3, 0, 1, -1, 0, -3, -4, 0, -3, -3, -2, 0, -1, -4, -3, -3, 4, 1, -1, -4],\n  [-1, 0, 0, 1, -3, 3, 4, -2, 0, -3, -3, 1, -1, -3, -1, 0, -1, -3, -2, -2, 1, 4, -1, -4],\n  [0, -1, -1, -1, -2, -1, -1, -1, -1, -1, -1, -1, -1, -1, -2, 0, 0, -2, -1, -1, -1, -1, -1, -4],\n  [-4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, -4, 1]];\n\n// Protein indexes for BLOSUM matrix\nconst ProtIndexes: {[id:string]:number} = {\n  'A': 0, 'R': 1, 'N': 2, 'D': 3, 'C': 4, 'Q': 5, 'E': 6, 'G': 7, 'H': 8,\n  'I': 9, 'L': 10, 'K': 11, 'M': 12, 'F': 13, 'P': 14, 'S': 15, 'T': 16,\n  'W': 17, 'Y': 18, 'V': 19, 'B': 20, 'Z': 21, 'X': 22, '*': 23\n};\n\ntype NeedlemanWunchArgs = mmDistanceFunctionArgs & {\n  gapOpen: number;\n  gapExtend: number;\n}\n\nconst defaultArgs: NeedlemanWunchArgs = {\n  gapOpen: 1,\n  gapExtend: 0.6,\n  scoringMatrix: BLOSUM62,\n  alphabetIndexes: ProtIndexes\n};\n\n/** Returns a function that calculates the distance between two sequences based on gap penalty and matrix\n * @param {Partial<NeedlemanWunchArgs>}args - arguments for Needleman-Wunch algorithm like gap penalty, Scoring matrix..\n * @return {mmDistanceFunctionType} - function that calculates the distance between two sequences\n*/\nexport function needlemanWunch(args: Partial<NeedlemanWunchArgs>): mmDistanceFunctionType {\n  const maxLen = 10000;\n  const charCodeArray = new Uint16Array(0x10000);\n  \n  const {gapOpen, gapExtend, scoringMatrix, alphabetIndexes} = {...defaultArgs, ...args};\n  Object.entries(alphabetIndexes).forEach(([k, v]) => charCodeArray[k.charCodeAt(0)] = v);\n  // As we don't need traceback, no need to store the whole matrix\n  // Intead, we will store only the last two rows\n  const matrix: Array<Float32Array> = [\n    new Float32Array(maxLen),\n    new Float32Array(maxLen)\n  ];\n  return (seq1: string, seq2: string) : number => {\n    // similarly, we need to keep track of what operation led to the current cell\n    // i.e. whether we came from the left, top or diagonal to assign gap open/gap extend penalty\n\n    const verticalGaps: boolean[] = new Array<boolean>(seq1.length +1).fill(false);\n    const horizontalGaps: boolean[] = new Array<boolean>(seq1.length +1).fill(false);\n    //variables to keep track which row we are in\n    // they will swap places on each iteration\n    let prevRow = 0;\n    let currRow = 1;\n    // Initialize first row\n    for (let i = 1; i < seq1.length + 1; i++) {\n      matrix[0][i] = -gapOpen - (i - 1) * gapExtend;\n      matrix[1][i] = 0;\n    }\n\n    // Calculate the rest of the matrix\n    for (let i = 1; i < seq2.length + 1; i++) {\n      matrix[currRow][0] = -gapOpen - (i - 1) * gapExtend;\n      for (let j = 1; j < seq1.length + 1; j++) {\n        const diagonal =\n          matrix[prevRow][j - 1] + scoringMatrix[charCodeArray[seq1.charCodeAt(j - 1)]][charCodeArray[seq2.charCodeAt(i - 1)]];\n        const top = matrix[prevRow][j] - (verticalGaps[j] ? gapExtend : gapOpen );\n        const left = matrix[currRow][j - 1] - (horizontalGaps[j - 1] ? gapExtend : gapOpen);\n        matrix[currRow][j] = Math.max(\n          diagonal, left, top\n        );\n        // update gap arrays\n        if (matrix[currRow][j] === diagonal) {\n          verticalGaps[j] = false;\n          horizontalGaps[j] = false;\n        } else if (matrix[currRow][j] === left) {\n          verticalGaps[j] = false;\n          horizontalGaps[j] = true;\n        } else {\n          verticalGaps[j] = true;\n          horizontalGaps[j] = false;\n        }\n      }\n      // Swap rows\n      prevRow = currRow;\n      currRow = (currRow + 1) % 2;\n    }\n    // as the matrix is the similarity matrix, but we are interested in distance,\n    // we need compare it to perfect match score to get reasonable distance\n    // const perfectMatchSeq1 = seq1.split('').map((c) => scoringMatrix[alphabetIndexes[c]][alphabetIndexes[c]])\n    //   .reduce((a, b) => a + b, 0);\n    // const perfectMatchSeq2 = seq2.split('').map((c) => scoringMatrix[alphabetIndexes[c]][alphabetIndexes[c]])\n    //   .reduce((a, b) => a + b, 0);\n    // const maxScore = Math.max(perfectMatchSeq1, perfectMatchSeq2);\n    const maxScore = Math.max(seq1.length, seq2.length);\n    return (maxScore - matrix[prevRow][seq1.length]) / maxScore;\n  };\n}\n"]}","const peq = new Uint32Array(0x10000);\nconst myers_32 = (a, b) => {\n const n = a.length;\n const m = b.length;\n const lst = 1 << (n - 1);\n let pv = -1;\n let mv = 0;\n let sc = n;\n let i = n;\n while (i--) {\n peq[a.charCodeAt(i)] |= 1 << i;\n }\n for (i = 0; i < m; i++) {\n let eq = peq[b.charCodeAt(i)];\n const xv = eq | mv;\n eq |= ((eq & pv) + pv) ^ pv;\n mv |= ~(eq | pv);\n pv &= eq;\n if (mv & lst) {\n sc++;\n }\n if (pv & lst) {\n sc--;\n }\n mv = (mv << 1) | 1;\n pv = (pv << 1) | ~(xv | mv);\n mv &= xv;\n }\n i = n;\n while (i--) {\n peq[a.charCodeAt(i)] = 0;\n }\n return sc;\n};\nconst myers_x = (b, a) => {\n const n = a.length;\n const m = b.length;\n const mhc = [];\n const phc = [];\n const hsize = Math.ceil(n / 32);\n const vsize = Math.ceil(m / 32);\n for (let i = 0; i < hsize; i++) {\n phc[i] = -1;\n mhc[i] = 0;\n }\n let j = 0;\n for (; j < vsize - 1; j++) {\n let mv = 0;\n let pv = -1;\n const start = j * 32;\n const vlen = Math.min(32, m) + start;\n for (let k = start; k < vlen; k++) {\n peq[b.charCodeAt(k)] |= 1 << k;\n }\n for (let i = 0; i < n; i++) {\n const eq = peq[a.charCodeAt(i)];\n const pb = (phc[(i / 32) | 0] >>> i) & 1;\n const mb = (mhc[(i / 32) | 0] >>> i) & 1;\n const xv = eq | mv;\n const xh = ((((eq | mb) & pv) + pv) ^ pv) | eq | mb;\n let ph = mv | ~(xh | pv);\n let mh = pv & xh;\n if ((ph >>> 31) ^ pb) {\n phc[(i / 32) | 0] ^= 1 << i;\n }\n if ((mh >>> 31) ^ mb) {\n mhc[(i / 32) | 0] ^= 1 << i;\n }\n ph = (ph << 1) | pb;\n mh = (mh << 1) | mb;\n pv = mh | ~(xv | ph);\n mv = ph & xv;\n }\n for (let k = start; k < vlen; k++) {\n peq[b.charCodeAt(k)] = 0;\n }\n }\n let mv = 0;\n let pv = -1;\n const start = j * 32;\n const vlen = Math.min(32, m - start) + start;\n for (let k = start; k < vlen; k++) {\n peq[b.charCodeAt(k)] |= 1 << k;\n }\n let score = m;\n for (let i = 0; i < n; i++) {\n const eq = peq[a.charCodeAt(i)];\n const pb = (phc[(i / 32) | 0] >>> i) & 1;\n const mb = (mhc[(i / 32) | 0] >>> i) & 1;\n const xv = eq | mv;\n const xh = ((((eq | mb) & pv) + pv) ^ pv) | eq | mb;\n let ph = mv | ~(xh | pv);\n let mh = pv & xh;\n score += (ph >>> (m - 1)) & 1;\n score -= (mh >>> (m - 1)) & 1;\n if ((ph >>> 31) ^ pb) {\n phc[(i / 32) | 0] ^= 1 << i;\n }\n if ((mh >>> 31) ^ mb) {\n mhc[(i / 32) | 0] ^= 1 << i;\n }\n ph = (ph << 1) | pb;\n mh = (mh << 1) | mb;\n pv = mh | ~(xv | ph);\n mv = ph & xv;\n }\n for (let k = start; k < vlen; k++) {\n peq[b.charCodeAt(k)] = 0;\n }\n return score;\n};\nconst distance = (a, b) => {\n if (a.length < b.length) {\n const tmp = b;\n b = a;\n a = tmp;\n }\n if (b.length === 0) {\n return a.length;\n }\n if (a.length <= 32) {\n return myers_32(a, b);\n }\n return myers_x(a, b);\n};\nconst closest = (str, arr) => {\n let min_distance = Infinity;\n let min_index = 0;\n for (let i = 0; i < arr.length; i++) {\n const dist = distance(str, arr[i]);\n if (dist < min_distance) {\n min_distance = dist;\n min_index = i;\n }\n }\n return arr[min_index];\n};\nexport { closest, distance };\n"],"names":["isNil","x","hamming","args","distanceF","scoringMatrix","alphabetIndexes","a","b","length","Object","keys","Error","indexes","matrix","minCharCode","Math","min","map","k","charCodeAt","scorringArray","Float32Array","entries","forEach","key","index","matrixRow","key2","index2","getDistanceF","threshold","seq1","seq2","diff","s1l","s2l","thresholdLimit","max","abs","result","i","levenstein","defaultArgs","gapOpen","gapExtend","needlemanWunch","charCodeArray","Uint16Array","v","verticalGaps","Array","fill","horizontalGaps","prevRow","currRow","j","diagonal","top","left","maxScore","peq","Uint32Array","distance","tmp","n","m","lst","pv","mv","sc","eq","xv","myers_32","mhc","phc","hsize","ceil","vsize","start","vlen","pb","mb","xh","ph","mh","score","myers_x"],"sourceRoot":""}
package/dist/361.js CHANGED
@@ -1,2 +1,2 @@
1
- "use strict";(self.webpackChunkbio=self.webpackChunkbio||[]).push([[361],{5697:(t,n,e)=>{e.d(n,{Dz:()=>y,FV:()=>c,KR:()=>a,MI:()=>f,NB:()=>h,UX:()=>l,WI:()=>k,Zd:()=>g,_h:()=>s,aW:()=>m,bX:()=>B,fX:()=>M,s:()=>C,yU:()=>d});var o=e(9657),r=e(1040),u=e(489);function i(t,n){const e=t.trueCount()+n.trueCount();if(0==e)return 1;const o=t.andWithCountBits(n,!0);return o/(e-o)}function a(t,n){return E(i(t,n))}function c(t,n){return E(i(new o.Z(t,32*t.length),new o.Z(n,32*n.length)))}function s(t,n){return E(function(t,n){const e=t.trueCount()+n.trueCount();return 0==e?0:2*t.andWithCountBits(n,!0)/e}(t,n))}function g(t,n){return E(function(t,n){const e=t.trueCount()*n.trueCount();return 0==e?0:t.andWithCountBits(n,!0)/Math.sqrt(e)}(t,n))}function k(t,n){return Math.sqrt(t.trueCount()+n.trueCount()-2*t.andWithCountBits(n,!0))}function l(t,n){return t.trueCount()+n.trueCount()-2*t.andWithCountBits(n,!0)}function h(t,n){return E(function(t,n){const e=t.trueCount()+n.trueCount(),o=t.andWithCountBits(n,!0);return o/(2*e-3*o)}(t,n))}function C(t,n){return E(function(t,n){const e=t.trueCount()+n.trueCount(),o=t.trueCount()*n.trueCount();return 0==o?0:t.andWithCountBits(n,!0)*e/(2*o)}(t,n))}function m(t,n){return E(function(t,n){const e=t.trueCount()+n.trueCount(),o=t.trueCount()*n.trueCount();return 0==o?0:(t.andWithCountBits(n,!0)*e-o)/o}(t,n))}function d(t,n){return E(function(t,n){const e=Math.min(t.trueCount(),n.trueCount());return 0==e?0:t.andWithCountBits(n,!0)/e}(t,n))}function y(t,n){return E(function(t,n){const e=Math.max(t.trueCount(),n.trueCount());return 0==e?0:t.andWithCountBits(n,!0)/e}(t,n))}function M(t,n){return E(function(t,n){return 0==t.length?0:t.andWithCountBits(n,!0)/t.length}(t,n))}function f(t,n){return E(function(t,n){const e=t.andWithCountBits(n,!0),o=t.countBits(!0)+n.countBits(!0),r=t.length,u=r-o+e;return e==r||u==r?1:e/o+u/(2*r-o)}(t,n))}function E(t){return 0===t?3402823e32:1/t-1}function B(t,n){return Math.abs(t-n)}r.gk.Tanimoto,r.gk.Dice,r.gk.Asymmetric,r.gk.BraunBlanquet,r.gk.Cosine,r.gk.Kulczynski,r.gk.McConnaughey,r.gk.RogotGoldberg,r.gk.Russel,r.gk.Sokal,r.gk.Hamming,r.gk.Euclidean,r.gk.Tanimoto,r.gk.Dice,r.gk.Asymmetric,r.gk.BraunBlanquet,r.gk.Cosine,r.gk.Kulczynski,r.gk.McConnaughey,r.gk.RogotGoldberg,r.gk.Russel,r.gk.Sokal,r.gk.Hamming,r.gk.Euclidean,r.gk.Tanimoto,r.gk.Dice,r.gk.Cosine,r.gk.Tanimoto,r.gk.Asymmetric,r.gk.Cosine,r.gk.Sokal,u.U.HAMMING,u.U.LEVENSHTEIN,u.U.MONOMER_CHEMICAL_DISTANCE},1040:(t,n,e)=>{var o,r,u,i,a,c;e.d(n,{CF:()=>r,Qe:()=>a,W:()=>o,Yc:()=>c,gd:()=>i,gk:()=>u}),function(t){t.Levenshtein="Levenshtein",t.JaroWinkler="Jaro-Winkler",t.Manhattan="Manhattan"}(o||(o={})),function(t){t.Euclidean="Euclidean"}(r||(r={})),function(t){t.Tanimoto="Tanimoto",t.Dice="Dice",t.Asymmetric="Asymmetric",t.BraunBlanquet="Braun-Blanquet",t.Cosine="Cosine",t.Kulczynski="Kulczynski",t.McConnaughey="Mc-Connaughey",t.RogotGoldberg="Rogot-Goldberg",t.Russel="Russel",t.Sokal="Sokal",t.Hamming="Hamming",t.Euclidean="Euclidean"}(u||(u={})),function(t){t.TanimotoIntArray="TanimotoIntArray"}(i||(i={})),function(t){t.Vector="Vector",t.String="String",t.BitArray="BitArray",t.MacroMolecule="MacroMolecule",t.Number="Number",t.IntArray="IntArray"}(a||(a={})),function(t){t.NumericDistance="NumericDistance"}(c||(c={}))},6361:(t,n,e)=>{e.d(n,{UH:()=>o.UH,sQ:()=>o.sQ}),e(1040);var o=e(7861)},7861:(t,n,e)=>{e.d(n,{UH:()=>y,sQ:()=>d});var o=e(1811),r=e(3979),u=e(5697),i=e(850),a=e(489),c=e(1040);const s={[c.CF.Euclidean]:i.dP},g={[c.W.Levenshtein]:o.T,[c.W.JaroWinkler]:r.H$,[c.W.Manhattan]:function(t,n){if(t.length!==n.length)return 1;{let e=0;for(let o=1;o<t.length;o++)e+=t[o]==n[o]?0:1;return e/t.length}}},k={[c.gk.Tanimoto]:u.KR,[c.gk.Dice]:u._h,[c.gk.Asymmetric]:u.yU,[c.gk.BraunBlanquet]:u.Dz,[c.gk.Cosine]:u.Zd,[c.gk.Kulczynski]:u.s,[c.gk.McConnaughey]:u.aW,[c.gk.RogotGoldberg]:u.MI,[c.gk.Russel]:u.fX,[c.gk.Sokal]:u.NB,[c.gk.Hamming]:u.UX,[c.gk.Euclidean]:u.WI},l={[c.gd.TanimotoIntArray]:u.FV},h={[c.Yc.NumericDistance]:u.bX},C={[c.Qe.Vector]:{[c.CF.Euclidean]:s[c.CF.Euclidean]},[c.Qe.String]:{[c.W.Levenshtein]:g[c.W.Levenshtein],[c.W.JaroWinkler]:g[c.W.JaroWinkler],[c.W.Manhattan]:g[c.W.Manhattan]},[c.Qe.BitArray]:{[c.gk.Tanimoto]:k[c.gk.Tanimoto],[c.gk.Dice]:k[c.gk.Dice],[c.gk.Asymmetric]:k[c.gk.Asymmetric],[c.gk.BraunBlanquet]:k[c.gk.BraunBlanquet],[c.gk.Cosine]:k[c.gk.Cosine],[c.gk.Kulczynski]:k[c.gk.Kulczynski],[c.gk.McConnaughey]:k[c.gk.McConnaughey],[c.gk.RogotGoldberg]:k[c.gk.RogotGoldberg],[c.gk.Russel]:k[c.gk.Russel],[c.gk.Sokal]:k[c.gk.Sokal]},[c.Qe.MacroMolecule]:{[a.U.HAMMING]:a.o[a.U.HAMMING],[a.U.LEVENSHTEIN]:a.o[a.U.LEVENSHTEIN],[a.U.NEEDLEMANN_WUNSCH]:a.o[a.U.NEEDLEMANN_WUNSCH],[a.U.MONOMER_CHEMICAL_DISTANCE]:a.o[a.U.MONOMER_CHEMICAL_DISTANCE]},[c.Qe.Number]:{[c.Yc.NumericDistance]:h[c.Yc.NumericDistance]},[c.Qe.IntArray]:{[c.gd.TanimotoIntArray]:l[c.gd.TanimotoIntArray]}},m=Object.keys(C).reduce(((t,n)=>{for(const e of Object.keys(C[n]))t[e]=n;return t}),{});function d(t){return"BitArray"==m[t]}class y{constructor(t){this.method=t,this.dataType=m[t]}getMeasure(t){const n=C;if(!n.hasOwnProperty(this.dataType)||!n[this.dataType].hasOwnProperty(this.method))throw new Error(`Unknown measure ${this.method} for data type ${this.dataType}`);return e=this.method,m[e]==c.Qe.MacroMolecule.toString()?n[this.dataType][this.method](t):n[this.dataType][this.method];var e}static getMetricByDataType(t){return Object.keys(C[t])}static get availableMeasures(){return Object.keys(C)}}},850:(t,n,e)=>{function o(t,n){let e=0;const o=t.length;if(o!==n.length)throw new Error("The dimensionality of the vectors must match");for(let r=0;r<o;++r)e+=Math.pow(t[r]-n[r],2);return Math.sqrt(e)}e.d(n,{dP:()=>o})}}]);
1
+ "use strict";(self.webpackChunkbio=self.webpackChunkbio||[]).push([[361],{5697:(t,n,e)=>{e.d(n,{Dz:()=>y,FV:()=>c,KR:()=>a,MI:()=>f,NB:()=>h,UX:()=>l,WI:()=>k,Zd:()=>g,_h:()=>s,aW:()=>m,bX:()=>N,fX:()=>M,s:()=>C,yU:()=>d});var o=e(9657),r=e(1040),u=e(489);function i(t,n){const e=t.trueCount()+n.trueCount();if(0==e)return 1;const o=t.andWithCountBits(n,!0);return o/(e-o)}function a(t,n){return E(i(t,n))}function c(t,n){return E(i(new o.Z(t,32*t.length),new o.Z(n,32*n.length)))}function s(t,n){return E(function(t,n){const e=t.trueCount()+n.trueCount();return 0==e?0:2*t.andWithCountBits(n,!0)/e}(t,n))}function g(t,n){return E(function(t,n){const e=t.trueCount()*n.trueCount();return 0==e?0:t.andWithCountBits(n,!0)/Math.sqrt(e)}(t,n))}function k(t,n){return Math.sqrt(t.trueCount()+n.trueCount()-2*t.andWithCountBits(n,!0))}function l(t,n){return t.trueCount()+n.trueCount()-2*t.andWithCountBits(n,!0)}function h(t,n){return E(function(t,n){const e=t.trueCount()+n.trueCount(),o=t.andWithCountBits(n,!0);return o/(2*e-3*o)}(t,n))}function C(t,n){return E(function(t,n){const e=t.trueCount()+n.trueCount(),o=t.trueCount()*n.trueCount();return 0==o?0:t.andWithCountBits(n,!0)*e/(2*o)}(t,n))}function m(t,n){return E(function(t,n){const e=t.trueCount()+n.trueCount(),o=t.trueCount()*n.trueCount();return 0==o?0:(t.andWithCountBits(n,!0)*e-o)/o}(t,n))}function d(t,n){return E(function(t,n){const e=Math.min(t.trueCount(),n.trueCount());return 0==e?0:t.andWithCountBits(n,!0)/e}(t,n))}function y(t,n){return E(function(t,n){const e=Math.max(t.trueCount(),n.trueCount());return 0==e?0:t.andWithCountBits(n,!0)/e}(t,n))}function M(t,n){return E(function(t,n){return 0==t.length?0:t.andWithCountBits(n,!0)/t.length}(t,n))}function f(t,n){return E(function(t,n){const e=t.andWithCountBits(n,!0),o=t.countBits(!0)+n.countBits(!0),r=t.length,u=r-o+e;return e==r||u==r?1:e/o+u/(2*r-o)}(t,n))}function E(t){return 0===t?3402823e32:1/t-1}function N(t,n){return Math.abs(t-n)}r.gk.Tanimoto,r.gk.Dice,r.gk.Asymmetric,r.gk.BraunBlanquet,r.gk.Cosine,r.gk.Kulczynski,r.gk.McConnaughey,r.gk.RogotGoldberg,r.gk.Russel,r.gk.Sokal,r.gk.Hamming,r.gk.Euclidean,r.gk.Tanimoto,r.gk.Dice,r.gk.Asymmetric,r.gk.BraunBlanquet,r.gk.Cosine,r.gk.Kulczynski,r.gk.McConnaughey,r.gk.RogotGoldberg,r.gk.Russel,r.gk.Sokal,r.gk.Hamming,r.gk.Euclidean,r.gk.Tanimoto,r.gk.Dice,r.gk.Cosine,r.gk.Tanimoto,r.gk.Asymmetric,r.gk.Cosine,r.gk.Sokal,u.U.HAMMING,u.U.LEVENSHTEIN,u.U.MONOMER_CHEMICAL_DISTANCE,u.U.NEEDLEMANN_WUNSCH},1040:(t,n,e)=>{var o,r,u,i,a,c;e.d(n,{CF:()=>r,Qe:()=>a,W:()=>o,Yc:()=>c,gd:()=>i,gk:()=>u}),function(t){t.Levenshtein="Levenshtein",t.JaroWinkler="Jaro-Winkler",t.Manhattan="Manhattan"}(o||(o={})),function(t){t.Euclidean="Euclidean"}(r||(r={})),function(t){t.Tanimoto="Tanimoto",t.Dice="Dice",t.Asymmetric="Asymmetric",t.BraunBlanquet="Braun-Blanquet",t.Cosine="Cosine",t.Kulczynski="Kulczynski",t.McConnaughey="Mc-Connaughey",t.RogotGoldberg="Rogot-Goldberg",t.Russel="Russel",t.Sokal="Sokal",t.Hamming="Hamming",t.Euclidean="Euclidean"}(u||(u={})),function(t){t.TanimotoIntArray="TanimotoIntArray"}(i||(i={})),function(t){t.Vector="Vector",t.String="String",t.BitArray="BitArray",t.MacroMolecule="MacroMolecule",t.Number="Number",t.IntArray="IntArray"}(a||(a={})),function(t){t.NumericDistance="NumericDistance"}(c||(c={}))},6361:(t,n,e)=>{e.d(n,{UH:()=>o.UH,sQ:()=>o.sQ}),e(1040);var o=e(7861)},7861:(t,n,e)=>{e.d(n,{UH:()=>y,sQ:()=>d});var o=e(1811),r=e(3979),u=e(5697),i=e(850),a=e(489),c=e(1040);const s={[c.CF.Euclidean]:i.dP},g={[c.W.Levenshtein]:o.T,[c.W.JaroWinkler]:r.H$,[c.W.Manhattan]:function(t,n){if(t.length!==n.length)return 1;{let e=0;for(let o=1;o<t.length;o++)e+=t[o]==n[o]?0:1;return e/t.length}}},k={[c.gk.Tanimoto]:u.KR,[c.gk.Dice]:u._h,[c.gk.Asymmetric]:u.yU,[c.gk.BraunBlanquet]:u.Dz,[c.gk.Cosine]:u.Zd,[c.gk.Kulczynski]:u.s,[c.gk.McConnaughey]:u.aW,[c.gk.RogotGoldberg]:u.MI,[c.gk.Russel]:u.fX,[c.gk.Sokal]:u.NB,[c.gk.Hamming]:u.UX,[c.gk.Euclidean]:u.WI},l={[c.gd.TanimotoIntArray]:u.FV},h={[c.Yc.NumericDistance]:u.bX},C={[c.Qe.Vector]:{[c.CF.Euclidean]:s[c.CF.Euclidean]},[c.Qe.String]:{[c.W.Levenshtein]:g[c.W.Levenshtein],[c.W.JaroWinkler]:g[c.W.JaroWinkler],[c.W.Manhattan]:g[c.W.Manhattan]},[c.Qe.BitArray]:{[c.gk.Tanimoto]:k[c.gk.Tanimoto],[c.gk.Dice]:k[c.gk.Dice],[c.gk.Asymmetric]:k[c.gk.Asymmetric],[c.gk.BraunBlanquet]:k[c.gk.BraunBlanquet],[c.gk.Cosine]:k[c.gk.Cosine],[c.gk.Kulczynski]:k[c.gk.Kulczynski],[c.gk.McConnaughey]:k[c.gk.McConnaughey],[c.gk.RogotGoldberg]:k[c.gk.RogotGoldberg],[c.gk.Russel]:k[c.gk.Russel],[c.gk.Sokal]:k[c.gk.Sokal]},[c.Qe.MacroMolecule]:{[a.U.HAMMING]:a.o[a.U.HAMMING],[a.U.LEVENSHTEIN]:a.o[a.U.LEVENSHTEIN],[a.U.NEEDLEMANN_WUNSCH]:a.o[a.U.NEEDLEMANN_WUNSCH],[a.U.MONOMER_CHEMICAL_DISTANCE]:a.o[a.U.MONOMER_CHEMICAL_DISTANCE]},[c.Qe.Number]:{[c.Yc.NumericDistance]:h[c.Yc.NumericDistance]},[c.Qe.IntArray]:{[c.gd.TanimotoIntArray]:l[c.gd.TanimotoIntArray]}},m=Object.keys(C).reduce(((t,n)=>{for(const e of Object.keys(C[n]))t[e]=n;return t}),{});function d(t){return"BitArray"==m[t]}class y{constructor(t){this.method=t,this.dataType=m[t]}getMeasure(t){const n=C;if(!n.hasOwnProperty(this.dataType)||!n[this.dataType].hasOwnProperty(this.method))throw new Error(`Unknown measure ${this.method} for data type ${this.dataType}`);return e=this.method,m[e]==c.Qe.MacroMolecule.toString()?n[this.dataType][this.method](t):n[this.dataType][this.method];var e}static getMetricByDataType(t){return Object.keys(C[t])}static get availableMeasures(){return Object.keys(C)}}},850:(t,n,e)=>{function o(t,n){let e=0;const o=t.length;if(o!==n.length)throw new Error("The dimensionality of the vectors must match");for(let r=0;r<o;++r)e+=Math.pow(t[r]-n[r],2);return Math.sqrt(e)}e.d(n,{dP:()=>o})}}]);
2
2
  //# sourceMappingURL=361.js.map