@cyanheads/openfda-mcp-server 0.1.6

package/dist/mcp-server/tools/definitions/search-drug-approvals.tool.js

@@ -0,0 +1,136 @@
+/**
+ * @fileoverview Tool for searching FDA drug application approvals (NDAs and ANDAs)
+ * via the Drugs@FDA endpoint.
+ * @module mcp-server/tools/definitions/search-drug-approvals
+ */
+import { tool, z } from '@cyanheads/mcp-ts-core';
+import { getOpenFdaService } from '../../../services/openfda/openfda-service.js';
+/** Exported tool definition for searching drug approvals. */
+export const searchDrugApprovalsTool = tool('openfda_search_drug_approvals', {
+    description: 'Search the Drugs@FDA database for drug application approvals (NDAs and ANDAs). Returns application details, sponsor info, and full submission history.',
+    annotations: { readOnlyHint: true },
+    input: z.object({
+        search: z
+            .string()
+            .optional()
+            .describe('openFDA search query. Examples: openfda.brand_name:"humira", sponsor_name:"pfizer", submissions.submission_type:"ORIG" AND submissions.review_priority:"PRIORITY". Omit to browse recent.'),
+        sort: z
+            .string()
+            .optional()
+            .describe('Sort field and order. Example: submissions.submission_status_date:desc'),
+        limit: z
+            .number()
+            .min(1)
+            .max(1000)
+            .default(10)
+            .describe('Maximum number of records to return (1-1000, default 10)'),
+        skip: z
+            .number()
+            .min(0)
+            .max(25000)
+            .default(0)
+            .describe('Number of records to skip for pagination (0-25000, default 0)'),
+    }),
+    output: z.object({
+        meta: z
+            .object({
+            total: z.number().describe('Total matching records'),
+            skip: z.number().describe('Pagination offset'),
+            limit: z.number().describe('Records returned'),
+            lastUpdated: z.string().describe('Dataset last updated date'),
+        })
+            .describe('Response metadata'),
+        results: z
+            .array(z.record(z.string(), z.any()))
+            .describe('Drug application records with submission history'),
+        message: z
+            .string()
+            .optional()
+            .describe('Guidance when results are empty or search can be refined'),
+    }),
+    async handler(input, ctx) {
+        const service = getOpenFdaService();
+        const response = await service.query('drug/drugsfda', {
+            search: input.search,
+            sort: input.sort,
+            limit: input.limit,
+            skip: input.skip,
+        }, ctx);
+        ctx.log.info('Drug approval search completed', {
+            search: input.search,
+            total: response.meta.total,
+            returned: response.results.length,
+        });
+        const message = response.results.length === 0
+            ? 'No drug approvals matched the query. Try broader terms, check field names (e.g. openfda.brand_name, sponsor_name), or remove filters.'
+            : undefined;
+        return {
+            meta: response.meta,
+            results: response.results,
+            message,
+        };
+    },
+    format: (result) => {
+        if (result.results.length === 0) {
+            return [
+                {
+                    type: 'text',
+                    text: result.message ?? 'No drug approvals found.',
+                },
+            ];
+        }
+        const lines = [
+            `**${result.meta.total.toLocaleString()} total results** (showing ${result.results.length}, skip: ${result.meta.skip}) | Data updated: ${result.meta.lastUpdated}\n`,
+        ];
+        for (const r of result.results) {
+            const openfda = r.openfda ?? {};
+            const brandName = (openfda.brand_name ?? [])[0] ?? '';
+            const genericName = (openfda.generic_name ?? [])[0] ?? '';
+            const title = brandName || genericName || r.application_number || 'Unknown';
+            lines.push(`### ${title}`);
+            lines.push(`**Application:** ${r.application_number ?? 'N/A'} | **Sponsor:** ${r.sponsor_name ?? 'N/A'}`);
+            if (brandName && genericName)
+                lines.push(`**Brand:** ${brandName} | **Generic:** ${genericName}`);
+            if (openfda.route)
+                lines.push(`**Route:** ${openfda.route.join(', ')}`);
+            if (openfda.product_type)
+                lines.push(`**Type:** ${openfda.product_type.join(', ')}`);
+            const products = r.products ?? [];
+            if (products.length > 0) {
+                lines.push('**Products:**');
+                for (const p of products) {
+                    const ingredients = (p.active_ingredients ?? [])
+                        .map((i) => `${i.name} ${i.strength ?? ''}`.trim())
+                        .join(', ');
+                    const parts = [
+                        p.brand_name,
+                        ingredients ? `(${ingredients})` : null,
+                        p.dosage_form,
+                        p.route,
+                        p.marketing_status,
+                    ].filter(Boolean);
+                    lines.push(`- ${parts.join(' | ')}`);
+                }
+            }
+            const submissions = r.submissions ?? [];
+            if (submissions.length > 0) {
+                lines.push('**Submissions:**');
+                for (const s of submissions.slice(0, 10)) {
+                    const parts = [
+                        s.submission_type,
+                        s.submission_number ? `#${s.submission_number}` : null,
+                        s.submission_status,
+                        s.submission_status_date,
+                        s.review_priority ? `(${s.review_priority})` : null,
+                    ].filter(Boolean);
+                    lines.push(`- ${parts.join(' | ')}`);
+                }
+                if (submissions.length > 10)
+                    lines.push(`- ... and ${submissions.length - 10} more`);
+            }
+            lines.push('');
+        }
+        return [{ type: 'text', text: lines.join('\n') }];
+    },
+});
+//# sourceMappingURL=search-drug-approvals.tool.js.map

package/dist/mcp-server/tools/definitions/search-drug-approvals.tool.js.map

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package/dist/mcp-server/tools/definitions/search-recalls.tool.d.ts

@@ -0,0 +1,30 @@
+/**
+ * @fileoverview Tool for searching openFDA enforcement reports and recall actions.
+ * @module mcp-server/tools/definitions/search-recalls
+ */
+import { z } from '@cyanheads/mcp-ts-core';
+export declare const searchRecallsTool: import("@cyanheads/mcp-ts-core").ToolDefinition<z.ZodObject<{
+    category: z.ZodEnum<{
+        drug: "drug";
+        food: "food";
+        device: "device";
+    }>;
+    endpoint: z.ZodDefault<z.ZodEnum<{
+        enforcement: "enforcement";
+        recall: "recall";
+    }>>;
+    search: z.ZodOptional<z.ZodString>;
+    sort: z.ZodOptional<z.ZodString>;
+    limit: z.ZodDefault<z.ZodNumber>;
+    skip: z.ZodDefault<z.ZodNumber>;
+}, z.core.$strip>, z.ZodObject<{
+    meta: z.ZodObject<{
+        total: z.ZodNumber;
+        skip: z.ZodNumber;
+        limit: z.ZodNumber;
+        lastUpdated: z.ZodString;
+    }, z.core.$strip>;
+    results: z.ZodArray<z.ZodRecord<z.ZodString, z.ZodAny>>;
+    message: z.ZodOptional<z.ZodString>;
+}, z.core.$strip>>;
+//# sourceMappingURL=search-recalls.tool.d.ts.map

package/dist/mcp-server/tools/definitions/search-recalls.tool.d.ts.map

@@ -0,0 +1 @@
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package/dist/mcp-server/tools/definitions/search-recalls.tool.js

@@ -0,0 +1,105 @@
+/**
+ * @fileoverview Tool for searching openFDA enforcement reports and recall actions.
+ * @module mcp-server/tools/definitions/search-recalls
+ */
+import { tool, z } from '@cyanheads/mcp-ts-core';
+import { validationError } from '@cyanheads/mcp-ts-core/errors';
+import { getOpenFdaService } from '../../../services/openfda/openfda-service.js';
+const Category = z.enum(['drug', 'food', 'device']).describe('Product category');
+const Endpoint = z
+    .enum(['enforcement', 'recall'])
+    .default('enforcement')
+    .describe('Report type. Default enforcement. The recall endpoint is only available for devices.');
+/** Truncate a string to `max` characters, appending ellipsis when trimmed. */
+function truncate(value, max) {
+    if (!value)
+        return 'N/A';
+    return value.length > max ? `${value.slice(0, max)}...` : value;
+}
+export const searchRecallsTool = tool('openfda_search_recalls', {
+    description: 'Search enforcement reports and recall actions across drugs, food, and devices.',
+    annotations: { readOnlyHint: true },
+    input: z.object({
+        category: Category,
+        endpoint: Endpoint,
+        search: z
+            .string()
+            .optional()
+            .describe('openFDA search query. Examples: classification:"Class I", recalling_firm:"pfizer", reason_for_recall:"undeclared allergen".'),
+        sort: z.string().optional().describe('Sort expression. Example: report_date:desc.'),
+        limit: z
+            .number()
+            .min(1)
+            .max(1000)
+            .default(10)
+            .describe('Maximum number of records to return (1-1000).'),
+        skip: z.number().min(0).max(25000).default(0).describe('Pagination offset (0-25000).'),
+    }),
+    output: z.object({
+        meta: z
+            .object({
+            total: z.number().describe('Total matching records'),
+            skip: z.number().describe('Pagination offset'),
+            limit: z.number().describe('Records returned'),
+            lastUpdated: z.string().describe('Dataset last updated date'),
+        })
+            .describe('Response metadata'),
+        results: z.array(z.record(z.string(), z.any())).describe('Enforcement/recall records'),
+        message: z
+            .string()
+            .optional()
+            .describe('Guidance when results are empty or search can be refined'),
+    }),
+    async handler(input, ctx) {
+        const endpointValue = input.endpoint ?? 'enforcement';
+        if (endpointValue === 'recall' && input.category !== 'device') {
+            throw validationError('The recall endpoint is only available for devices. Use enforcement for drug and food recalls.');
+        }
+        const service = getOpenFdaService();
+        const response = await service.query(`${input.category}/${endpointValue}`, {
+            search: input.search,
+            sort: input.sort,
+            limit: input.limit,
+            skip: input.skip,
+        }, ctx);
+        ctx.log.info('Recall search completed', {
+            category: input.category,
+            endpoint: endpointValue,
+            total: response.meta.total,
+        });
+        return {
+            meta: response.meta,
+            results: response.results,
+            message: response.results.length === 0
+                ? `No recall/enforcement records matched${input.search ? ` search: ${input.search}` : ''} in ${input.category}/${endpointValue}. Try broadening filters or check field names (e.g. classification, recalling_firm, reason_for_recall).`
+                : undefined,
+        };
+    },
+    format: (result) => {
+        if (result.results.length === 0) {
+            return [
+                {
+                    type: 'text',
+                    text: result.message ?? 'No results found.',
+                },
+            ];
+        }
+        const header = `**${result.meta.total.toLocaleString()} total records** (showing ${result.results.length}, offset ${result.meta.skip}) | Last updated: ${result.meta.lastUpdated}\n`;
+        const records = result.results.map((r) => {
+            const lines = [
+                `**Recall #${r.recall_number ?? 'N/A'}** — ${r.classification ?? 'Unclassified'}`,
+                `Firm: ${r.recalling_firm ?? 'N/A'}`,
+                `Product: ${truncate(r.product_description, 300)}`,
+                `Reason: ${truncate(r.reason_for_recall, 300)}`,
+                `Status: ${r.status ?? 'N/A'} | ${r.voluntary_mandated ?? 'N/A'}`,
+            ];
+            if (r.distribution_pattern) {
+                lines.push(`Distribution: ${r.distribution_pattern}`);
+            }
+            return lines.join('\n');
+        });
+        const body = records.join('\n\n---\n\n');
+        return [{ type: 'text', text: `${header}\n${body}` }];
+    },
+});
+//# sourceMappingURL=search-recalls.tool.js.map

package/dist/mcp-server/tools/definitions/search-recalls.tool.js.map

@@ -0,0 +1 @@
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package/dist/services/openfda/openfda-service.d.ts

@@ -0,0 +1,25 @@
+/**
+ * @fileoverview Generic openFDA API client with retry, rate-limit awareness, and error normalization.
+ * @module services/openfda/openfda-service
+ */
+import type { Context } from '@cyanheads/mcp-ts-core';
+import { type ServerConfig } from '../../config/server-config.js';
+import type { OpenFdaQueryParams, OpenFdaResponse } from './types.js';
+export declare class OpenFdaService {
+    private readonly baseUrl;
+    private readonly apiKey;
+    constructor(config: ServerConfig);
+    /**
+     * Execute a query against any openFDA endpoint.
+     *
+     * Handles retry with exponential backoff for transient errors (429, 5xx).
+     * Returns an empty result set for 404 (valid query, zero matches).
+     */
+    query<T = Record<string, unknown>>(endpoint: string, params: OpenFdaQueryParams, ctx: Context): Promise<OpenFdaResponse<T>>;
+    private buildUrl;
+    private normalizeResponse;
+    private handleErrorResponse;
+}
+export declare function initOpenFdaService(): void;
+export declare function getOpenFdaService(): OpenFdaService;
+//# sourceMappingURL=openfda-service.d.ts.map

package/dist/services/openfda/openfda-service.d.ts.map

@@ -0,0 +1 @@
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package/dist/services/openfda/openfda-service.js

@@ -0,0 +1,111 @@
+/**
+ * @fileoverview Generic openFDA API client with retry, rate-limit awareness, and error normalization.
+ * @module services/openfda/openfda-service
+ */
+import { rateLimited, serviceUnavailable, validationError } from '@cyanheads/mcp-ts-core/errors';
+import { withRetry } from '@cyanheads/mcp-ts-core/utils';
+import { getServerConfig } from '../../config/server-config.js';
+const REQUEST_TIMEOUT_MS = 15_000;
+export class OpenFdaService {
+    baseUrl;
+    apiKey;
+    constructor(config) {
+        this.baseUrl = config.baseUrl;
+        this.apiKey = config.apiKey;
+    }
+    /**
+     * Execute a query against any openFDA endpoint.
+     *
+     * Handles retry with exponential backoff for transient errors (429, 5xx).
+     * Returns an empty result set for 404 (valid query, zero matches).
+     */
+    async query(endpoint, params, ctx) {
+        return await withRetry(async () => {
+            const url = this.buildUrl(endpoint, params);
+            ctx.log.debug('Querying openFDA', { endpoint, params });
+            const response = await fetch(url.toString(), {
+                signal: AbortSignal.any([ctx.signal, AbortSignal.timeout(REQUEST_TIMEOUT_MS)]),
+                headers: { Accept: 'application/json' },
+            });
+            if (response.ok) {
+                const data = (await response.json());
+                return this.normalizeResponse(data);
+            }
+            return this.handleErrorResponse(response, endpoint);
+        }, {
+            operation: `openFDA:${endpoint}`,
+            context: { requestId: ctx.requestId, timestamp: ctx.timestamp },
+            baseDelayMs: 1_000,
+            signal: ctx.signal,
+        });
+    }
+    buildUrl(endpoint, params) {
+        const url = new URL(`/${endpoint}.json`, this.baseUrl);
+        if (params.search)
+            url.searchParams.set('search', params.search);
+        if (params.count)
+            url.searchParams.set('count', params.count);
+        if (params.sort)
+            url.searchParams.set('sort', params.sort);
+        if (params.limit !== undefined)
+            url.searchParams.set('limit', String(params.limit));
+        if (params.skip !== undefined)
+            url.searchParams.set('skip', String(params.skip));
+        if (this.apiKey)
+            url.searchParams.set('api_key', this.apiKey);
+        return url;
+    }
+    normalizeResponse(data) {
+        const meta = data.meta;
+        const pagination = meta?.results;
+        return {
+            meta: {
+                total: pagination?.total ?? 0,
+                skip: pagination?.skip ?? 0,
+                limit: pagination?.limit ?? 0,
+                lastUpdated: meta?.last_updated ?? 'unknown',
+            },
+            results: data.results ?? [],
+        };
+    }
+    async handleErrorResponse(response, endpoint) {
+        const body = (await response.json().catch(() => null));
+        const errorObj = body?.error;
+        const errorMessage = errorObj?.message ?? `HTTP ${response.status}`;
+        if (response.status === 404) {
+            return {
+                meta: { total: 0, skip: 0, limit: 0, lastUpdated: 'unknown' },
+                results: [],
+            };
+        }
+        if (response.status === 429) {
+            throw rateLimited(this.apiKey
+                ? 'openFDA rate limit exceeded (240 req/min or 120K/day with key). Retry after a brief wait.'
+                : 'openFDA rate limit exceeded (240 req/min or 1K/day without key). Configure OPENFDA_API_KEY to increase to 120K/day.');
+        }
+        if (response.status >= 500) {
+            throw serviceUnavailable(`openFDA upstream error: ${errorMessage}`, {
+                endpoint,
+                status: response.status,
+            });
+        }
+        if (response.status === 400) {
+            if (/25000/i.test(errorMessage)) {
+                throw validationError('Pagination limit reached: skip cannot exceed 25000. Narrow the search query with additional filters or date ranges instead of increasing skip.', { endpoint });
+            }
+            throw validationError(`openFDA query error: ${errorMessage}. Check field names and query syntax — use AND/OR for boolean operators, quotes for exact match.`, { endpoint });
+        }
+        throw new Error(`openFDA returned HTTP ${response.status}: ${errorMessage}`);
+    }
+}
+/* --- Init / accessor pattern --- */
+let _service;
+export function initOpenFdaService() {
+    _service = new OpenFdaService(getServerConfig());
+}
+export function getOpenFdaService() {
+    if (!_service)
+        throw new Error('OpenFdaService not initialized — call initOpenFdaService() in setup()');
+    return _service;
+}
+//# sourceMappingURL=openfda-service.js.map

package/dist/services/openfda/openfda-service.js.map

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package/dist/services/openfda/types.d.ts

@@ -0,0 +1,30 @@
+/**
+ * @fileoverview Types for the openFDA service layer.
+ * @module services/openfda/types
+ */
+/** Pagination and freshness metadata from an openFDA response. */
+export interface OpenFdaMeta {
+    lastUpdated: string;
+    limit: number;
+    skip: number;
+    total: number;
+}
+/** Normalized openFDA API response. */
+export interface OpenFdaResponse<T = Record<string, unknown>> {
+    meta: OpenFdaMeta;
+    results: T[];
+}
+/** Term-count pair returned by openFDA count queries. */
+export interface OpenFdaCountResult {
+    count: number;
+    term: string;
+}
+/** Query parameters shared by all openFDA endpoints. */
+export interface OpenFdaQueryParams {
+    count?: string | undefined;
+    limit?: number | undefined;
+    search?: string | undefined;
+    skip?: number | undefined;
+    sort?: string | undefined;
+}
+//# sourceMappingURL=types.d.ts.map

package/dist/services/openfda/types.d.ts.map

@@ -0,0 +1 @@
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package/dist/services/openfda/types.js

@@ -0,0 +1,6 @@
+/**
+ * @fileoverview Types for the openFDA service layer.
+ * @module services/openfda/types
+ */
+export {};
+//# sourceMappingURL=types.js.map

package/dist/services/openfda/types.js.map

@@ -0,0 +1 @@
+{"version":3,"file":"types.js","sourceRoot":"","sources":["../../../src/services/openfda/types.ts"],"names":[],"mappings":"AAAA;;;GAGG"}

package/package.json

@@ -0,0 +1,88 @@
+{
+  "name": "@cyanheads/openfda-mcp-server",
+  "version": "0.1.6",
+  "mcpName": "io.github.cyanheads/openfda-mcp-server",
+  "description": "Query FDA data on drugs, food, devices, and recalls via openFDA. STDIO or Streamable HTTP.",
+  "type": "module",
+  "main": "dist/index.js",
+  "types": "dist/index.d.ts",
+  "bin": {
+    "openfda-mcp-server": "dist/index.js"
+  },
+  "files": ["dist/", "README.md", "LICENSE", "CLAUDE.md", "Dockerfile", "server.json"],
+  "scripts": {
+    "build": "bun run scripts/build.ts",
+    "rebuild": "bun run scripts/clean.ts && bun run build",
+    "clean": "bun run scripts/clean.ts",
+    "devcheck": "bun run scripts/devcheck.ts",
+    "tree": "bun run scripts/tree.ts",
+    "format": "biome check --write --unsafe",
+    "lint:mcp": "bun run scripts/lint-mcp.ts",
+    "test": "bunx vitest run",
+    "dev:stdio": "MCP_TRANSPORT_TYPE=stdio bun --watch src/index.ts",
+    "dev:http": "MCP_TRANSPORT_TYPE=http bun --watch src/index.ts",
+    "start:stdio": "MCP_TRANSPORT_TYPE=stdio bun ./dist/index.js",
+    "start:http": "MCP_TRANSPORT_TYPE=http bun ./dist/index.js"
+  },
+  "keywords": [
+    "mcp",
+    "mcp-server",
+    "model-context-protocol",
+    "openfda",
+    "fda",
+    "drug-safety",
+    "adverse-events",
+    "typescript"
+  ],
+  "repository": {
+    "type": "git",
+    "url": "git+https://github.com/cyanheads/openfda-mcp-server.git"
+  },
+  "homepage": "https://github.com/cyanheads/openfda-mcp-server#readme",
+  "bugs": {
+    "url": "https://github.com/cyanheads/openfda-mcp-server/issues"
+  },
+  "author": "cyanheads <casey@caseyjhand.com> (https://github.com/cyanheads/openfda-mcp-server#readme)",
+  "funding": [
+    {
+      "type": "github",
+      "url": "https://github.com/sponsors/cyanheads"
+    },
+    {
+      "type": "buy_me_a_coffee",
+      "url": "https://www.buymeacoffee.com/cyanheads"
+    }
+  ],
+  "license": "Apache-2.0",
+  "packageManager": "bun@1.3.11",
+  "engines": {
+    "node": ">=22.0.0",
+    "bun": ">=1.2.0"
+  },
+  "publishConfig": {
+    "access": "public"
+  },
+  "overrides": {
+    "brace-expansion": ">=2.0.3",
+    "express-rate-limit": ">=8.2.2",
+    "hono": ">=4.12.7",
+    "path-to-regexp": ">=8.4.0",
+    "picomatch": ">=4.0.4",
+    "yaml": ">=2.8.3"
+  },
+  "dependencies": {
+    "@cyanheads/mcp-ts-core": "^0.2.12",
+    "pino-pretty": "^13.1.3"
+  },
+  "devDependencies": {
+    "@biomejs/biome": "^2.4.10",
+    "@opentelemetry/api": "^1.9.1",
+    "@types/node": "^25.5.2",
+    "@vitest/coverage-istanbul": "^4.1.2",
+    "depcheck": "^1.4.7",
+    "ignore": "^7.0.5",
+    "tsc-alias": "^1.8.16",
+    "typescript": "^5.9.3",
+    "vitest": "^4.1.2"
+  }
+}