@cornerstonejs/nifti-volume-loader 1.67.0 → 1.67.1

package/dist/esm/helpers/convert.d.ts

@@ -1,4 +1,4 @@
-import type { Types } from '@cornerstonejs/core';
+import { Types } from '@cornerstonejs/core';
 declare const invertDataPerFrame: (dimensions: any, imageDataArray: any) => any;
 declare function rasToLps(niftiHeader: any): {
     origin: Types.Point3;

package/dist/esm/helpers/convert.js

@@ -1,10 +1,12 @@
+import { getShouldUseSharedArrayBuffer } from '@cornerstonejs/core';
 import { parseAffineMatrix } from './affineUtilities';
 const invertDataPerFrame = (dimensions, imageDataArray) => {
     let TypedArrayConstructor;
     let bytesPerVoxel;
     if (imageDataArray instanceof Uint8Array ||
         imageDataArray instanceof ArrayBuffer ||
-        imageDataArray instanceof SharedArrayBuffer) {
+        (getShouldUseSharedArrayBuffer() &&
+            imageDataArray instanceof SharedArrayBuffer)) {
         TypedArrayConstructor = Uint8Array;
         bytesPerVoxel = 1;
     }

package/dist/esm/helpers/convert.js.map

@@ -1 +1 @@
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package/dist/esm/helpers/fetchAndAllocateNiftiVolume.js

@@ -1,5 +1,5 @@
 import * as NiftiReader from 'nifti-reader-js';
-import { cache, utilities, Enums, eventTarget, triggerEvent, } from '@cornerstonejs/core';
+import { cache, utilities, Enums, eventTarget, triggerEvent, getShouldUseSharedArrayBuffer, } from '@cornerstonejs/core';
 import { vec3 } from 'gl-matrix';
 import makeVolumeMetadata from './makeVolumeMetadata';
 import NiftiImageVolume from '../NiftiImageVolume';
@@ -126,18 +126,24 @@ export default async function fetchAndAllocateNiftiVolume(volumeId) {
     }
     cache.decacheIfNecessaryUntilBytesAvailable(sizeInBytes);
     let scalarData;
+    const useSharedArrayBuffer = getShouldUseSharedArrayBuffer();
+    const buffer_size = dimensions[0] * dimensions[1] * dimensions[2];
     switch (BitsAllocated) {
         case 8:
             if (signed) {
                 throw new Error('8 Bit signed images are not yet supported by this plugin.');
             }
             else {
-                scalarData = createUint8SharedArray(dimensions[0] * dimensions[1] * dimensions[2]);
+                scalarData = useSharedArrayBuffer
+                    ? createUint8SharedArray(buffer_size)
+                    : new Uint8Array(buffer_size);
             }
             break;
         case 16:
         case 32:
-            scalarData = createFloat32SharedArray(dimensions[0] * dimensions[1] * dimensions[2]);
+            scalarData = useSharedArrayBuffer
+                ? createFloat32SharedArray(buffer_size)
+                : new Float32Array(buffer_size);
             break;
     }
     scalarData.set(typedNiftiArray);

package/dist/esm/helpers/fetchAndAllocateNiftiVolume.js.map

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package/dist/umd/index.js

@@ -1,2 +1,2 @@
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s{littleEndian=!1;dim_info=0;dims=[];intent_p1=0;intent_p2=0;intent_p3=0;intent_code=0;datatypeCode=0;numBitsPerVoxel=0;slice_start=0;slice_end=0;slice_code=0;pixDims=[];vox_offset=0;scl_slope=1;scl_inter=0;xyzt_units=0;cal_max=0;cal_min=0;slice_duration=0;toffset=0;description="";aux_file="";intent_name="";qform_code=0;sform_code=0;quatern_a=0;quatern_b=0;quatern_c=0;quatern_d=0;qoffset_x=0;qoffset_y=0;qoffset_z=0;affine=[[1,0,0,0],[0,1,0,0],[0,0,1,0],[0,0,0,1]];qfac=1;quatern_R;magic="0";isHDR=!1;extensionFlag=[0,0,0,0];extensionSize=0;extensionCode=0;extensions=[];static TYPE_NONE=0;static TYPE_BINARY=1;static TYPE_UINT8=2;static TYPE_INT16=4;static TYPE_INT32=8;static TYPE_FLOAT32=16;static TYPE_COMPLEX64=32;static TYPE_FLOAT64=64;static TYPE_RGB24=128;static TYPE_INT8=256;static TYPE_UINT16=512;static TYPE_UINT32=768;static TYPE_INT64=1024;static TYPE_UINT64=1280;static TYPE_FLOAT128=1536;static TYPE_COMPLEX128=1792;static TYPE_COMPLEX256=2048;static XFORM_UNKNOWN=0;static XFORM_SCANNER_ANAT=1;static XFORM_ALIGNED_ANAT=2;static XFORM_TALAIRACH=3;static XFORM_MNI_152=4;static SPATIAL_UNITS_MASK=7;static TEMPORAL_UNITS_MASK=56;static UNITS_UNKNOWN=0;static UNITS_METER=1;static UNITS_MM=2;static UNITS_MICRON=3;static UNITS_SEC=8;static UNITS_MSEC=16;static UNITS_USEC=24;static UNITS_HZ=32;static UNITS_PPM=40;static UNITS_RADS=48;static MAGIC_COOKIE=348;static STANDARD_HEADER_SIZE=348;static MAGIC_NUMBER_LOCATION=344;static MAGIC_NUMBER=[110,43,49];static MAGIC_NUMBER2=[110,105,49];static EXTENSION_HEADER_SIZE=8;readHeader(t){var e,i,r,o,a=new DataView(t),l=n.Utils.getIntAt(a,0,this.littleEndian);if(l!==s.MAGIC_COOKIE&&(this.littleEndian=!0,l=n.Utils.getIntAt(a,0,this.littleEndian)),l!==s.MAGIC_COOKIE)throw new Error("This does not appear to be a NIFTI file!");for(this.dim_info=n.Utils.getByteAt(a,39),e=0;e<8;e+=1)o=40+2*e,this.dims[e]=n.Utils.getShortAt(a,o,this.littleEndian);for(this.intent_p1=n.Utils.getFloatAt(a,56,this.littleEndian),this.intent_p2=n.Utils.getFloatAt(a,60,this.littleEndian),this.intent_p3=n.Utils.getFloatAt(a,64,this.littleEndian),this.intent_code=n.Utils.getShortAt(a,68,this.littleEndian),this.datatypeCode=n.Utils.getShortAt(a,70,this.littleEndian),this.numBitsPerVoxel=n.Utils.getShortAt(a,72,this.littleEndian),this.slice_start=n.Utils.getShortAt(a,74,this.littleEndian),e=0;e<8;e+=1)o=76+4*e,this.pixDims[e]=n.Utils.getFloatAt(a,o,this.littleEndian);if(this.vox_offset=n.Utils.getFloatAt(a,108,this.littleEndian),this.scl_slope=n.Utils.getFloatAt(a,112,this.littleEndian),this.scl_inter=n.Utils.getFloatAt(a,116,this.littleEndian),this.slice_end=n.Utils.getShortAt(a,120,this.littleEndian),this.slice_code=n.Utils.getByteAt(a,122),this.xyzt_units=n.Utils.getByteAt(a,123),this.cal_max=n.Utils.getFloatAt(a,124,this.littleEndian),this.cal_min=n.Utils.getFloatAt(a,128,this.littleEndian),this.slice_duration=n.Utils.getFloatAt(a,132,this.littleEndian),this.toffset=n.Utils.getFloatAt(a,136,this.littleEndian),this.description=n.Utils.getStringAt(a,148,228),this.aux_file=n.Utils.getStringAt(a,228,252),this.qform_code=n.Utils.getShortAt(a,252,this.littleEndian),this.sform_code=n.Utils.getShortAt(a,254,this.littleEndian),this.quatern_b=n.Utils.getFloatAt(a,256,this.littleEndian),this.quatern_c=n.Utils.getFloatAt(a,260,this.littleEndian),this.quatern_d=n.Utils.getFloatAt(a,264,this.littleEndian),this.quatern_a=Math.sqrt(1-(Math.pow(this.quatern_b,2)+Math.pow(this.quatern_c,2)+Math.pow(this.quatern_d,2))),this.qoffset_x=n.Utils.getFloatAt(a,268,this.littleEndian),this.qoffset_y=n.Utils.getFloatAt(a,272,this.littleEndian),this.qoffset_z=n.Utils.getFloatAt(a,276,this.littleEndian),this.qform_code<1&&this.sform_code<1&&(this.affine[0][0]=this.pixDims[1],this.affine[1][1]=this.pixDims[2],this.affine[2][2]=this.pixDims[3]),this.qform_code>0&&this.sform_code<this.qform_code){const t=this.quatern_a,e=this.quatern_b,n=this.quatern_c,s=this.quatern_d;for(this.qfac=0===this.pixDims[0]?1:this.pixDims[0],this.quatern_R=[[t*t+e*e-n*n-s*s,2*e*n-2*t*s,2*e*s+2*t*n],[2*e*n+2*t*s,t*t+n*n-e*e-s*s,2*n*s-2*t*e],[2*e*s-2*t*n,2*n*s+2*t*e,t*t+s*s-n*n-e*e]],i=0;i<3;i+=1)for(r=0;r<3;r+=1)this.affine[i][r]=this.quatern_R[i][r]*this.pixDims[r+1],2===r&&(this.affine[i][r]*=this.qfac);this.affine[0][3]=this.qoffset_x,this.affine[1][3]=this.qoffset_y,this.affine[2][3]=this.qoffset_z}else if(this.sform_code>0)for(i=0;i<3;i+=1)for(r=0;r<4;r+=1)o=280+4*(4*i+r),this.affine[i][r]=n.Utils.getFloatAt(a,o,this.littleEndian);this.affine[3][0]=0,this.affine[3][1]=0,this.affine[3][2]=0,this.affine[3][3]=1,this.intent_name=n.Utils.getStringAt(a,328,344),this.magic=n.Utils.getStringAt(a,344,348),this.isHDR=this.magic===String.fromCharCode.apply(null,s.MAGIC_NUMBER2),a.byteLength>s.MAGIC_COOKIE&&(this.extensionFlag[0]=n.Utils.getByteAt(a,348),this.extensionFlag[1]=n.Utils.getByteAt(a,349),this.extensionFlag[2]=n.Utils.getByteAt(a,350),this.extensionFlag[3]=n.Utils.getByteAt(a,351),this.extensionFlag[0]&&(this.extensions=n.Utils.getExtensionsAt(a,this.getExtensionLocation(),this.littleEndian,this.vox_offset),this.extensionSize=this.extensions[0].esize,this.extensionCode=this.extensions[0].ecode))}toFormattedString(){var t=n.Utils.formatNumber,e="";return e+="Dim Info = "+this.dim_info+"\n",e+="Image Dimensions (1-8): "+this.dims[0]+", "+this.dims[1]+", "+this.dims[2]+", "+this.dims[3]+", "+this.dims[4]+", "+this.dims[5]+", "+this.dims[6]+", "+this.dims[7]+"\n",e+="Intent Parameters (1-3): "+this.intent_p1+", "+this.intent_p2+", "+this.intent_p3+"\n",e+="Intent Code = "+this.intent_code+"\n",e+="Datatype = "+this.datatypeCode+" ("+this.getDatatypeCodeString(this.datatypeCode)+")\n",e+="Bits Per Voxel = "+this.numBitsPerVoxel+"\n",e+="Slice Start = "+this.slice_start+"\n",e+="Voxel Dimensions (1-8): "+t(this.pixDims[0])+", "+t(this.pixDims[1])+", "+t(this.pixDims[2])+", "+t(this.pixDims[3])+", "+t(this.pixDims[4])+", "+t(this.pixDims[5])+", "+t(this.pixDims[6])+", "+t(this.pixDims[7])+"\n",e+="Image Offset = "+this.vox_offset+"\n",e+="Data Scale:  Slope = "+t(this.scl_slope)+"  Intercept = "+t(this.scl_inter)+"\n",e+="Slice End = "+this.slice_end+"\n",e+="Slice Code = "+this.slice_code+"\n",e+="Units Code = "+this.xyzt_units+" ("+this.getUnitsCodeString(s.SPATIAL_UNITS_MASK&this.xyzt_units)+", "+this.getUnitsCodeString(s.TEMPORAL_UNITS_MASK&this.xyzt_units)+")\n",e+="Display Range:  Max = "+t(this.cal_max)+"  Min = "+t(this.cal_min)+"\n",e+="Slice Duration = "+this.slice_duration+"\n",e+="Time Axis Shift = "+this.toffset+"\n",e+='Description: "'+this.description+'"\n',e+='Auxiliary File: "'+this.aux_file+'"\n',e+="Q-Form Code = "+this.qform_code+" ("+this.getTransformCodeString(this.qform_code)+")\n",e+="S-Form Code = "+this.sform_code+" ("+this.getTransformCodeString(this.sform_code)+")\n",e+="Quaternion Parameters:  b = "+t(this.quatern_b)+"  c = "+t(this.quatern_c)+"  d = "+t(this.quatern_d)+"\n",e+="Quaternion Offsets:  x = "+this.qoffset_x+"  y = "+this.qoffset_y+"  z = "+this.qoffset_z+"\n",e+="S-Form Parameters X: "+t(this.affine[0][0])+", "+t(this.affine[0][1])+", "+t(this.affine[0][2])+", "+t(this.affine[0][3])+"\n",e+="S-Form Parameters Y: "+t(this.affine[1][0])+", "+t(this.affine[1][1])+", "+t(this.affine[1][2])+", "+t(this.affine[1][3])+"\n",e+="S-Form Parameters Z: "+t(this.affine[2][0])+", "+t(this.affine[2][1])+", "+t(this.affine[2][2])+", "+t(this.affine[2][3])+"\n",e+='Intent Name: "'+this.intent_name+'"\n',this.extensionFlag[0]&&(e+="Extension: Size = "+this.extensionSize+"  Code = "+this.extensionCode+"\n"),e}getDatatypeCodeString=function(t){return t===s.TYPE_UINT8?"1-Byte Unsigned Integer":t===s.TYPE_INT16?"2-Byte Signed Integer":t===s.TYPE_INT32?"4-Byte Signed Integer":t===s.TYPE_FLOAT32?"4-Byte Float":t===s.TYPE_FLOAT64?"8-Byte Float":t===s.TYPE_RGB24?"RGB":t===s.TYPE_INT8?"1-Byte Signed Integer":t===s.TYPE_UINT16?"2-Byte Unsigned Integer":t===s.TYPE_UINT32?"4-Byte Unsigned Integer":t===s.TYPE_INT64?"8-Byte Signed Integer":t===s.TYPE_UINT64?"8-Byte Unsigned Integer":"Unknown"};getTransformCodeString=function(t){return t===s.XFORM_SCANNER_ANAT?"Scanner":t===s.XFORM_ALIGNED_ANAT?"Aligned":t===s.XFORM_TALAIRACH?"Talairach":t===s.XFORM_MNI_152?"MNI":"Unknown"};getUnitsCodeString=function(t){return t===s.UNITS_METER?"Meters":t===s.UNITS_MM?"Millimeters":t===s.UNITS_MICRON?"Microns":t===s.UNITS_SEC?"Seconds":t===s.UNITS_MSEC?"Milliseconds":t===s.UNITS_USEC?"Microseconds":t===s.UNITS_HZ?"Hz":t===s.UNITS_PPM?"PPM":t===s.UNITS_RADS?"Rads":"Unknown"};getQformMat(){return this.convertNiftiQFormToNiftiSForm(this.quatern_b,this.quatern_c,this.quatern_d,this.qoffset_x,this.qoffset_y,this.qoffset_z,this.pixDims[1],this.pixDims[2],this.pixDims[3],this.pixDims[0])}convertNiftiQFormToNiftiSForm(t,e,i,n,s,r,o,a,l,h){var f,c,u,d,p=[[0,0,0,0],[0,0,0,0],[0,0,0,0],[0,0,0,0]],g=t,m=e,_=i;return p[3][0]=p[3][1]=p[3][2]=0,p[3][3]=1,(f=1-(g*g+m*m+_*_))<1e-7?(g*=f=1/Math.sqrt(g*g+m*m+_*_),m*=f,_*=f,f=0):f=Math.sqrt(f),c=o>0?o:1,u=a>0?a:1,d=l>0?l:1,h<0&&(d=-d),p[0][0]=(f*f+g*g-m*m-_*_)*c,p[0][1]=2*(g*m-f*_)*u,p[0][2]=2*(g*_+f*m)*d,p[1][0]=2*(g*m+f*_)*c,p[1][1]=(f*f+m*m-g*g-_*_)*u,p[1][2]=2*(m*_-f*g)*d,p[2][0]=2*(g*_-f*m)*c,p[2][1]=2*(m*_+f*g)*u,p[2][2]=(f*f+_*_-m*m-g*g)*d,p[0][3]=n,p[1][3]=s,p[2][3]=r,p}convertNiftiSFormToNEMA(t){var e,i,n,s,r,o,a,l,h,f,c,u,d,p,g,m,_,v,I,E,y,A,b,T,x,U,N,S,F,M,w,C,O;if(p=0,U=[[0,0,0],[0,0,0],[0,0,0]],N=[[0,0,0],[0,0,0],[0,0,0]],e=t[0][0],i=t[0][1],n=t[0][2],s=t[1][0],r=t[1][1],o=t[1][2],a=t[2][0],l=t[2][1],h=t[2][2],0===(f=Math.sqrt(e*e+s*s+a*a)))return null;if(e/=f,s/=f,a/=f,0===(f=Math.sqrt(i*i+r*r+l*l)))return null;if(f=e*(i/=f)+s*(r/=f)+a*(l/=f),Math.abs(f)>1e-4){if(i-=f*e,r-=f*s,l-=f*a,0===(f=Math.sqrt(i*i+r*r+l*l)))return null;i/=f,r/=f,l/=f}if(0===(f=Math.sqrt(n*n+o*o+h*h))?(n=s*l-a*r,o=a*i-l*e,h=e*r-s*i):(n/=f,o/=f,h/=f),f=e*n+s*o+a*h,Math.abs(f)>1e-4){if(n-=f*e,o-=f*s,h-=f*a,0===(f=Math.sqrt(n*n+o*o+h*h)))return null;n/=f,o/=f,h/=f}if(f=i*n+r*o+l*h,Math.abs(f)>1e-4){if(n-=f*i,o-=f*r,h-=f*l,0===(f=Math.sqrt(n*n+o*o+h*h)))return null;n/=f,o/=f,h/=f}if(U[0][0]=e,U[0][1]=i,U[0][2]=n,U[1][0]=s,U[1][1]=r,U[1][2]=o,U[2][0]=a,U[2][1]=l,U[2][2]=h,0===(c=this.nifti_mat33_determ(U)))return null;for(x=-666,v=y=A=b=1,I=2,E=3,u=1;u<=3;u+=1)for(d=1;d<=3;d+=1)if(u!==d)for(p=1;p<=3;p+=1)if(u!==p&&d!==p)for(N[0][0]=N[0][1]=N[0][2]=N[1][0]=N[1][1]=N[1][2]=N[2][0]=N[2][1]=N[2][2]=0,g=-1;g<=1;g+=2)for(m=-1;m<=1;m+=2)for(_=-1;_<=1;_+=2)N[0][u-1]=g,N[1][d-1]=m,N[2][p-1]=_,this.nifti_mat33_determ(N)*c>0&&(f=(T=this.nifti_mat33_mul(N,U))[0][0]+T[1][1]+T[2][2])>x&&(x=f,v=u,I=d,E=p,y=g,A=m,b=_);switch(S=F=M=w=C=O="",v*y){case 1:S="X",w="+";break;case-1:S="X",w="-";break;case 2:S="Y",w="+";break;case-2:S="Y",w="-";break;case 3:S="Z",w="+";break;case-3:S="Z",w="-"}switch(I*A){case 1:F="X",C="+";break;case-1:F="X",C="-";break;case 2:F="Y",C="+";break;case-2:F="Y",C="-";break;case 3:F="Z",C="+";break;case-3:F="Z",C="-"}switch(E*b){case 1:M="X",O="+";break;case-1:M="X",O="-";break;case 2:M="Y",O="+";break;case-2:M="Y",O="-";break;case 3:M="Z",O="+";break;case-3:M="Z",O="-"}return S+F+M+w+C+O}nifti_mat33_mul=function(t,e){var i,n,s=[[0,0,0],[0,0,0],[0,0,0]];for(i=0;i<3;i+=1)for(n=0;n<3;n+=1)s[i][n]=t[i][0]*e[0][n]+t[i][1]*e[1][n]+t[i][2]*e[2][n];return s};nifti_mat33_determ=function(t){var e,i,n,s,r,o,a,l,h;return e=t[0][0],i=t[0][1],n=t[0][2],s=t[1][0],r=t[1][1],o=t[1][2],a=t[2][0],l=t[2][1],e*r*(h=t[2][2])-e*l*o-s*i*h+s*l*n+a*i*o-a*r*n};getExtensionLocation(){return s.MAGIC_COOKIE+4}getExtensionSize(t){return n.Utils.getIntAt(t,this.getExtensionLocation(),this.littleEndian)}getExtensionCode(t){return n.Utils.getIntAt(t,this.getExtensionLocation()+4,this.littleEndian)}addExtension(t,e=-1){-1==e?this.extensions.push(t):this.extensions.splice(e,0,t),this.vox_offset+=t.esize}removeExtension(t){let e=this.extensions[t];e&&(this.vox_offset-=e.esize),this.extensions.splice(t,1)}toArrayBuffer(t=!1){let e=352;if(t)for(let t of this.extensions)e+=t.esize;let i=new Uint8Array(e),n=new DataView(i.buffer);n.setInt32(0,348,this.littleEndian),n.setUint8(39,this.dim_info);for(let t=0;t<8;t++)n.setUint16(40+2*t,this.dims[t],this.littleEndian);n.setFloat32(56,this.intent_p1,this.littleEndian),n.setFloat32(60,this.intent_p2,this.littleEndian),n.setFloat32(64,this.intent_p3,this.littleEndian),n.setInt16(68,this.intent_code,this.littleEndian),n.setInt16(70,this.datatypeCode,this.littleEndian),n.setInt16(72,this.numBitsPerVoxel,this.littleEndian),n.setInt16(74,this.slice_start,this.littleEndian);for(let t=0;t<8;t++)n.setFloat32(76+4*t,this.pixDims[t],this.littleEndian);n.setFloat32(108,this.vox_offset,this.littleEndian),n.setFloat32(112,this.scl_slope,this.littleEndian),n.setFloat32(116,this.scl_inter,this.littleEndian),n.setInt16(120,this.slice_end,this.littleEndian),n.setUint8(122,this.slice_code),n.setUint8(123,this.xyzt_units),n.setFloat32(124,this.cal_max,this.littleEndian),n.setFloat32(128,this.cal_min,this.littleEndian),n.setFloat32(132,this.slice_duration,this.littleEndian),n.setFloat32(136,this.toffset,this.littleEndian),i.set(Buffer.from(this.description),148),i.set(Buffer.from(this.aux_file),228),n.setInt16(252,this.qform_code,this.littleEndian),n.setInt16(254,this.sform_code,this.littleEndian),n.setFloat32(256,this.quatern_b,this.littleEndian),n.setFloat32(260,this.quatern_c,this.littleEndian),n.setFloat32(264,this.quatern_d,this.littleEndian),n.setFloat32(268,this.qoffset_x,this.littleEndian),n.setFloat32(272,this.qoffset_y,this.littleEndian),n.setFloat32(276,this.qoffset_z,this.littleEndian);const s=this.affine.flat();for(let t=0;t<12;t++)n.setFloat32(280+4*t,s[t],this.littleEndian);if(i.set(Buffer.from(this.intent_name),328),i.set(Buffer.from(this.magic),344),t){i.set(Uint8Array.from([1,0,0,0]),348);let t=this.getExtensionLocation();for(const e of this.extensions)n.setInt32(t,e.esize,e.littleEndian),n.setInt32(t+4,e.ecode,e.littleEndian),i.set(new Uint8Array(e.edata),t+8),t+=e.esize}else i.set(new Uint8Array(4).fill(0),348);return i.buffer}}e.NIFTI1=s},103:(t,e,i)=>{Object.defineProperty(e,"__esModule",{value:!0}),e.NIFTI2=void 0;const n=i(232),s=i(517);class r{littleEndian=!1;dim_info=0;dims=[];intent_p1=0;intent_p2=0;intent_p3=0;intent_code=0;datatypeCode=0;numBitsPerVoxel=0;slice_start=0;slice_end=0;slice_code=0;pixDims=[];vox_offset=0;scl_slope=1;scl_inter=0;xyzt_units=0;cal_max=0;cal_min=0;slice_duration=0;toffset=0;description="";aux_file="";intent_name="";qform_code=0;sform_code=0;quatern_b=0;quatern_c=0;quatern_d=0;qoffset_x=0;qoffset_y=0;qoffset_z=0;affine=[[1,0,0,0],[0,1,0,0],[0,0,1,0],[0,0,0,1]];magic="0";extensionFlag=[0,0,0,0];extensions=[];extensionSize=0;extensionCode=0;static MAGIC_COOKIE=540;static MAGIC_NUMBER_LOCATION=4;static MAGIC_NUMBER=[110,43,50,0,13,10,26,10];static MAGIC_NUMBER2=[110,105,50,0,13,10,26,10];readHeader(t){var e,i,n,o,a=new DataView(t),l=s.Utils.getIntAt(a,0,this.littleEndian);if(l!==r.MAGIC_COOKIE&&(this.littleEndian=!0,l=s.Utils.getIntAt(a,0,this.littleEndian)),l!==r.MAGIC_COOKIE)throw new Error("This does not appear to be a NIFTI file!");for(this.magic=s.Utils.getStringAt(a,4,12),this.datatypeCode=s.Utils.getShortAt(a,12,this.littleEndian),this.numBitsPerVoxel=s.Utils.getShortAt(a,14,this.littleEndian),e=0;e<8;e+=1)o=16+8*e,this.dims[e]=s.Utils.getLongAt(a,o,this.littleEndian);for(this.intent_p1=s.Utils.getDoubleAt(a,80,this.littleEndian),this.intent_p2=s.Utils.getDoubleAt(a,88,this.littleEndian),this.intent_p3=s.Utils.getDoubleAt(a,96,this.littleEndian),e=0;e<8;e+=1)o=104+8*e,this.pixDims[e]=s.Utils.getDoubleAt(a,o,this.littleEndian);for(this.vox_offset=s.Utils.getLongAt(a,168,this.littleEndian),this.scl_slope=s.Utils.getDoubleAt(a,176,this.littleEndian),this.scl_inter=s.Utils.getDoubleAt(a,184,this.littleEndian),this.cal_max=s.Utils.getDoubleAt(a,192,this.littleEndian),this.cal_min=s.Utils.getDoubleAt(a,200,this.littleEndian),this.slice_duration=s.Utils.getDoubleAt(a,208,this.littleEndian),this.toffset=s.Utils.getDoubleAt(a,216,this.littleEndian),this.slice_start=s.Utils.getLongAt(a,224,this.littleEndian),this.slice_end=s.Utils.getLongAt(a,232,this.littleEndian),this.description=s.Utils.getStringAt(a,240,320),this.aux_file=s.Utils.getStringAt(a,320,344),this.qform_code=s.Utils.getIntAt(a,344,this.littleEndian),this.sform_code=s.Utils.getIntAt(a,348,this.littleEndian),this.quatern_b=s.Utils.getDoubleAt(a,352,this.littleEndian),this.quatern_c=s.Utils.getDoubleAt(a,360,this.littleEndian),this.quatern_d=s.Utils.getDoubleAt(a,368,this.littleEndian),this.qoffset_x=s.Utils.getDoubleAt(a,376,this.littleEndian),this.qoffset_y=s.Utils.getDoubleAt(a,384,this.littleEndian),this.qoffset_z=s.Utils.getDoubleAt(a,392,this.littleEndian),i=0;i<3;i+=1)for(n=0;n<4;n+=1)o=400+8*(4*i+n),this.affine[i][n]=s.Utils.getDoubleAt(a,o,this.littleEndian);this.affine[3][0]=0,this.affine[3][1]=0,this.affine[3][2]=0,this.affine[3][3]=1,this.slice_code=s.Utils.getIntAt(a,496,this.littleEndian),this.xyzt_units=s.Utils.getIntAt(a,500,this.littleEndian),this.intent_code=s.Utils.getIntAt(a,504,this.littleEndian),this.intent_name=s.Utils.getStringAt(a,508,524),this.dim_info=s.Utils.getByteAt(a,524),a.byteLength>r.MAGIC_COOKIE&&(this.extensionFlag[0]=s.Utils.getByteAt(a,540),this.extensionFlag[1]=s.Utils.getByteAt(a,541),this.extensionFlag[2]=s.Utils.getByteAt(a,542),this.extensionFlag[3]=s.Utils.getByteAt(a,543),this.extensionFlag[0]&&(this.extensions=s.Utils.getExtensionsAt(a,this.getExtensionLocation(),this.littleEndian,this.vox_offset),this.extensionSize=this.extensions[0].esize,this.extensionCode=this.extensions[0].ecode))}toFormattedString(){var t=s.Utils.formatNumber,e="";return e+="Datatype = "+ +this.datatypeCode+" ("+this.getDatatypeCodeString(this.datatypeCode)+")\n",e+="Bits Per Voxel =  = "+this.numBitsPerVoxel+"\n",e+="Image Dimensions (1-8): "+this.dims[0]+", "+this.dims[1]+", "+this.dims[2]+", "+this.dims[3]+", "+this.dims[4]+", "+this.dims[5]+", "+this.dims[6]+", "+this.dims[7]+"\n",e+="Intent Parameters (1-3): "+this.intent_p1+", "+this.intent_p2+", "+this.intent_p3+"\n",e+="Voxel Dimensions (1-8): "+t(this.pixDims[0])+", "+t(this.pixDims[1])+", "+t(this.pixDims[2])+", "+t(this.pixDims[3])+", "+t(this.pixDims[4])+", "+t(this.pixDims[5])+", "+t(this.pixDims[6])+", "+t(this.pixDims[7])+"\n",e+="Image Offset = "+this.vox_offset+"\n",e+="Data Scale:  Slope = "+t(this.scl_slope)+"  Intercept = "+t(this.scl_inter)+"\n",e+="Display Range:  Max = "+t(this.cal_max)+"  Min = "+t(this.cal_min)+"\n",e+="Slice Duration = "+this.slice_duration+"\n",e+="Time Axis Shift = "+this.toffset+"\n",e+="Slice Start = "+this.slice_start+"\n",e+="Slice End = "+this.slice_end+"\n",e+='Description: "'+this.description+'"\n',e+='Auxiliary File: "'+this.aux_file+'"\n',e+="Q-Form Code = "+this.qform_code+" ("+this.getTransformCodeString(this.qform_code)+")\n",e+="S-Form Code = "+this.sform_code+" ("+this.getTransformCodeString(this.sform_code)+")\n",e+="Quaternion Parameters:  b = "+t(this.quatern_b)+"  c = "+t(this.quatern_c)+"  d = "+t(this.quatern_d)+"\n",e+="Quaternion Offsets:  x = "+this.qoffset_x+"  y = "+this.qoffset_y+"  z = "+this.qoffset_z+"\n",e+="S-Form Parameters X: "+t(this.affine[0][0])+", "+t(this.affine[0][1])+", "+t(this.affine[0][2])+", "+t(this.affine[0][3])+"\n",e+="S-Form Parameters Y: "+t(this.affine[1][0])+", "+t(this.affine[1][1])+", "+t(this.affine[1][2])+", "+t(this.affine[1][3])+"\n",e+="S-Form Parameters Z: "+t(this.affine[2][0])+", "+t(this.affine[2][1])+", "+t(this.affine[2][2])+", "+t(this.affine[2][3])+"\n",e+="Slice Code = "+this.slice_code+"\n",e+="Units Code = "+this.xyzt_units+" ("+this.getUnitsCodeString(n.NIFTI1.SPATIAL_UNITS_MASK&this.xyzt_units)+", "+this.getUnitsCodeString(n.NIFTI1.TEMPORAL_UNITS_MASK&this.xyzt_units)+")\n",e+="Intent Code = "+this.intent_code+"\n",(e+='Intent Name: "'+this.intent_name+'"\n')+"Dim Info = "+this.dim_info+"\n"}getExtensionLocation=function(){return r.MAGIC_COOKIE+4};getExtensionSize=n.NIFTI1.prototype.getExtensionSize;getExtensionCode=n.NIFTI1.prototype.getExtensionCode;addExtension=n.NIFTI1.prototype.addExtension;removeExtension=n.NIFTI1.prototype.removeExtension;getDatatypeCodeString=n.NIFTI1.prototype.getDatatypeCodeString;getTransformCodeString=n.NIFTI1.prototype.getTransformCodeString;getUnitsCodeString=n.NIFTI1.prototype.getUnitsCodeString;getQformMat=n.NIFTI1.prototype.getQformMat;convertNiftiQFormToNiftiSForm=n.NIFTI1.prototype.convertNiftiQFormToNiftiSForm;convertNiftiSFormToNEMA=n.NIFTI1.prototype.convertNiftiSFormToNEMA;nifti_mat33_mul=n.NIFTI1.prototype.nifti_mat33_mul;nifti_mat33_determ=n.NIFTI1.prototype.nifti_mat33_determ;toArrayBuffer(t=!1){let e=544;if(t)for(let t of this.extensions)e+=t.esize;let i=new Uint8Array(e),n=new DataView(i.buffer);n.setInt32(0,540,this.littleEndian),i.set(Buffer.from(this.magic),4),n.setInt16(12,this.datatypeCode,this.littleEndian),n.setInt16(14,this.numBitsPerVoxel,this.littleEndian);for(let t=0;t<8;t++)n.setBigInt64(16+8*t,BigInt(this.dims[t]),this.littleEndian);n.setFloat64(80,this.intent_p1,this.littleEndian),n.setFloat64(88,this.intent_p2,this.littleEndian),n.setFloat64(96,this.intent_p3,this.littleEndian);for(let t=0;t<8;t++)n.setFloat64(104+8*t,this.pixDims[t],this.littleEndian);n.setBigInt64(168,BigInt(this.vox_offset),this.littleEndian),n.setFloat64(176,this.scl_slope,this.littleEndian),n.setFloat64(184,this.scl_inter,this.littleEndian),n.setFloat64(192,this.cal_max,this.littleEndian),n.setFloat64(200,this.cal_min,this.littleEndian),n.setFloat64(208,this.slice_duration,this.littleEndian),n.setFloat64(216,this.toffset,this.littleEndian),n.setBigInt64(224,BigInt(this.slice_start),this.littleEndian),n.setBigInt64(232,BigInt(this.slice_end),this.littleEndian),i.set(Buffer.from(this.description),240),i.set(Buffer.from(this.aux_file),320),n.setInt32(344,this.qform_code,this.littleEndian),n.setInt32(348,this.sform_code,this.littleEndian),n.setFloat64(352,this.quatern_b,this.littleEndian),n.setFloat64(360,this.quatern_c,this.littleEndian),n.setFloat64(368,this.quatern_d,this.littleEndian),n.setFloat64(376,this.qoffset_x,this.littleEndian),n.setFloat64(384,this.qoffset_y,this.littleEndian),n.setFloat64(392,this.qoffset_z,this.littleEndian);const s=this.affine.flat();for(let t=0;t<12;t++)n.setFloat64(400+8*t,s[t],this.littleEndian);if(n.setInt32(496,this.slice_code,this.littleEndian),n.setInt32(500,this.xyzt_units,this.littleEndian),n.setInt32(504,this.intent_code,this.littleEndian),i.set(Buffer.from(this.intent_name),508),n.setUint8(524,this.dim_info),t){i.set(Uint8Array.from([1,0,0,0]),540);let t=this.getExtensionLocation();for(const e of this.extensions)n.setInt32(t,e.esize,e.littleEndian),n.setInt32(t+4,e.ecode,e.littleEndian),i.set(new Uint8Array(e.edata),t+8),t+=e.esize}else i.set(new Uint8Array(4).fill(0),540);return i.buffer}}e.NIFTI2=r},517:(t,e,i)=>{Object.defineProperty(e,"__esModule",{value:!0}),e.Utils=void 0;const n=i(237);class s{static crcTable=null;static GUNZIP_MAGIC_COOKIE1=31;static GUNZIP_MAGIC_COOKIE2=139;static getStringAt(t,e,i){var n,s,r="";for(n=e;n<i;n+=1)0!==(s=t.getUint8(n))&&(r+=String.fromCharCode(s));return r}static getByteAt=function(t,e){return t.getInt8(e)};static getShortAt=function(t,e,i){return t.getInt16(e,i)};static getIntAt(t,e,i){return t.getInt32(e,i)}static getFloatAt(t,e,i){return t.getFloat32(e,i)}static getDoubleAt(t,e,i){return t.getFloat64(e,i)}static getLongAt(t,e,i){var n,r=[],o=0;for(n=0;n<8;n+=1)r[n]=s.getByteAt(t,e+n);for(n=r.length-1;n>=0;n--)o=256*o+r[n];return o}static getExtensionsAt(t,e,i,r){let o=[],a=e;for(;a<r;){let e=i,l=s.getIntAt(t,a,i);if(!l)break;if(l+a>r&&(e=!e,l=s.getIntAt(t,a,e),l+a>r))throw new Error("This does not appear to be a valid NIFTI extension");if(l%16!=0)throw new Error("This does not appear to be a NIFTI extension");let h=s.getIntAt(t,a+4,e),f=t.buffer.slice(a+8,a+l);console.log("extensionByteIndex: "+(a+8)+" esize: "+l),console.log(f);let c=new n.NIFTIEXTENSION(l,h,f,e);o.push(c),a+=l}return o}static toArrayBuffer(t){var e,i,n;for(e=new ArrayBuffer(t.length),i=new Uint8Array(e),n=0;n<t.length;n+=1)i[n]=t[n];return e}static isString(t){return"string"==typeof t||t instanceof String}static formatNumber(t,e=void 0){let i;return i=s.isString(t)?Number(t):t,i=e?i.toPrecision(5):i.toPrecision(7),parseFloat(i)}static makeCRCTable(){let t,e=[];for(var i=0;i<256;i++){t=i;for(var n=0;n<8;n++)t=1&t?3988292384^t>>>1:t>>>1;e[i]=t}return e}static crc32(t){s.crcTable||(s.crcTable=s.makeCRCTable());const e=s.crcTable;let i=-1;for(var n=0;n<t.byteLength;n++)i=i>>>8^e[255&(i^t.getUint8(n))];return(-1^i)>>>0}}e.Utils=s},953:e=>{e.exports=t},976:t=>{t.exports=e},471:(t,e)=>{Object.defineProperty(e,"__esModule",{value:!0});var i={},n=function(t,e,n,s,r){var o=new Worker(i[e]||(i[e]=URL.createObjectURL(new Blob([t+';addEventListener("error",function(e){e=e.error;postMessage({$e$:[e.message,e.code,e.stack]})})'],{type:"text/javascript"}))));return o.onmessage=function(t){var e=t.data,i=e.$e$;if(i){var n=new Error(i[0]);n.code=i[1],n.stack=i[2],r(n,null)}else r(null,e)},o.postMessage(n,s),o},s=Uint8Array,r=Uint16Array,o=Int32Array,a=new s([0,0,0,0,0,0,0,0,1,1,1,1,2,2,2,2,3,3,3,3,4,4,4,4,5,5,5,5,0,0,0,0]),l=new s([0,0,0,0,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,13,13,0,0]),h=new s([16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15]),f=function(t,e){for(var i=new r(31),n=0;n<31;++n)i[n]=e+=1<<t[n-1];var s=new o(i[30]);for(n=1;n<30;++n)for(var a=i[n];a<i[n+1];++a)s[a]=a-i[n]<<5|n;return{b:i,r:s}},c=f(a,2),u=c.b,d=c.r;u[28]=258,d[258]=28;for(var p=f(l,0),g=p.b,m=p.r,_=new r(32768),v=0;v<32768;++v){var I=(43690&v)>>1|(21845&v)<<1;I=(61680&(I=(52428&I)>>2|(13107&I)<<2))>>4|(3855&I)<<4,_[v]=((65280&I)>>8|(255&I)<<8)>>1}var E=function(t,e,i){for(var n=t.length,s=0,o=new r(e);s<n;++s)t[s]&&++o[t[s]-1];var a,l=new r(e);for(s=1;s<e;++s)l[s]=l[s-1]+o[s-1]<<1;if(i){a=new r(1<<e);var h=15-e;for(s=0;s<n;++s)if(t[s])for(var f=s<<4|t[s],c=e-t[s],u=l[t[s]-1]++<<c,d=u|(1<<c)-1;u<=d;++u)a[_[u]>>h]=f}else for(a=new r(n),s=0;s<n;++s)t[s]&&(a[s]=_[l[t[s]-1]++]>>15-t[s]);return a},y=new s(288);for(v=0;v<144;++v)y[v]=8;for(v=144;v<256;++v)y[v]=9;for(v=256;v<280;++v)y[v]=7;for(v=280;v<288;++v)y[v]=8;var A=new s(32);for(v=0;v<32;++v)A[v]=5;var b=E(y,9,0),T=E(y,9,1),x=E(A,5,0),U=E(A,5,1),N=function(t){for(var e=t[0],i=1;i<t.length;++i)t[i]>e&&(e=t[i]);return e},S=function(t,e,i){var n=e/8|0;return(t[n]|t[n+1]<<8)>>(7&e)&i},F=function(t,e){var i=e/8|0;return(t[i]|t[i+1]<<8|t[i+2]<<16)>>(7&e)},M=function(t){return(t+7)/8|0},w=function(t,e,i){return(null==e||e<0)&&(e=0),(null==i||i>t.length)&&(i=t.length),new s(t.subarray(e,i))};e.FlateErrorCode={UnexpectedEOF:0,InvalidBlockType:1,InvalidLengthLiteral:2,InvalidDistance:3,StreamFinished:4,NoStreamHandler:5,InvalidHeader:6,NoCallback:7,InvalidUTF8:8,ExtraFieldTooLong:9,InvalidDate:10,FilenameTooLong:11,StreamFinishing:12,InvalidZipData:13,UnknownCompressionMethod:14};var C=["unexpected EOF","invalid block type","invalid length/literal","invalid distance","stream finished","no stream handler",,"no callback","invalid UTF-8 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s{littleEndian=!1;dim_info=0;dims=[];intent_p1=0;intent_p2=0;intent_p3=0;intent_code=0;datatypeCode=0;numBitsPerVoxel=0;slice_start=0;slice_end=0;slice_code=0;pixDims=[];vox_offset=0;scl_slope=1;scl_inter=0;xyzt_units=0;cal_max=0;cal_min=0;slice_duration=0;toffset=0;description="";aux_file="";intent_name="";qform_code=0;sform_code=0;quatern_a=0;quatern_b=0;quatern_c=0;quatern_d=0;qoffset_x=0;qoffset_y=0;qoffset_z=0;affine=[[1,0,0,0],[0,1,0,0],[0,0,1,0],[0,0,0,1]];qfac=1;quatern_R;magic="0";isHDR=!1;extensionFlag=[0,0,0,0];extensionSize=0;extensionCode=0;extensions=[];static TYPE_NONE=0;static TYPE_BINARY=1;static TYPE_UINT8=2;static TYPE_INT16=4;static TYPE_INT32=8;static TYPE_FLOAT32=16;static TYPE_COMPLEX64=32;static TYPE_FLOAT64=64;static TYPE_RGB24=128;static TYPE_INT8=256;static TYPE_UINT16=512;static TYPE_UINT32=768;static TYPE_INT64=1024;static TYPE_UINT64=1280;static TYPE_FLOAT128=1536;static TYPE_COMPLEX128=1792;static TYPE_COMPLEX256=2048;static XFORM_UNKNOWN=0;static XFORM_SCANNER_ANAT=1;static XFORM_ALIGNED_ANAT=2;static XFORM_TALAIRACH=3;static XFORM_MNI_152=4;static SPATIAL_UNITS_MASK=7;static TEMPORAL_UNITS_MASK=56;static UNITS_UNKNOWN=0;static UNITS_METER=1;static UNITS_MM=2;static UNITS_MICRON=3;static UNITS_SEC=8;static UNITS_MSEC=16;static UNITS_USEC=24;static UNITS_HZ=32;static UNITS_PPM=40;static UNITS_RADS=48;static MAGIC_COOKIE=348;static STANDARD_HEADER_SIZE=348;static MAGIC_NUMBER_LOCATION=344;static MAGIC_NUMBER=[110,43,49];static MAGIC_NUMBER2=[110,105,49];static EXTENSION_HEADER_SIZE=8;readHeader(t){var e,i,r,o,a=new DataView(t),l=n.Utils.getIntAt(a,0,this.littleEndian);if(l!==s.MAGIC_COOKIE&&(this.littleEndian=!0,l=n.Utils.getIntAt(a,0,this.littleEndian)),l!==s.MAGIC_COOKIE)throw new Error("This does not appear to be a NIFTI file!");for(this.dim_info=n.Utils.getByteAt(a,39),e=0;e<8;e+=1)o=40+2*e,this.dims[e]=n.Utils.getShortAt(a,o,this.littleEndian);for(this.intent_p1=n.Utils.getFloatAt(a,56,this.littleEndian),this.intent_p2=n.Utils.getFloatAt(a,60,this.littleEndian),this.intent_p3=n.Utils.getFloatAt(a,64,this.littleEndian),this.intent_code=n.Utils.getShortAt(a,68,this.littleEndian),this.datatypeCode=n.Utils.getShortAt(a,70,this.littleEndian),this.numBitsPerVoxel=n.Utils.getShortAt(a,72,this.littleEndian),this.slice_start=n.Utils.getShortAt(a,74,this.littleEndian),e=0;e<8;e+=1)o=76+4*e,this.pixDims[e]=n.Utils.getFloatAt(a,o,this.littleEndian);if(this.vox_offset=n.Utils.getFloatAt(a,108,this.littleEndian),this.scl_slope=n.Utils.getFloatAt(a,112,this.littleEndian),this.scl_inter=n.Utils.getFloatAt(a,116,this.littleEndian),this.slice_end=n.Utils.getShortAt(a,120,this.littleEndian),this.slice_code=n.Utils.getByteAt(a,122),this.xyzt_units=n.Utils.getByteAt(a,123),this.cal_max=n.Utils.getFloatAt(a,124,this.littleEndian),this.cal_min=n.Utils.getFloatAt(a,128,this.littleEndian),this.slice_duration=n.Utils.getFloatAt(a,132,this.littleEndian),this.toffset=n.Utils.getFloatAt(a,136,this.littleEndian),this.description=n.Utils.getStringAt(a,148,228),this.aux_file=n.Utils.getStringAt(a,228,252),this.qform_code=n.Utils.getShortAt(a,252,this.littleEndian),this.sform_code=n.Utils.getShortAt(a,254,this.littleEndian),this.quatern_b=n.Utils.getFloatAt(a,256,this.littleEndian),this.quatern_c=n.Utils.getFloatAt(a,260,this.littleEndian),this.quatern_d=n.Utils.getFloatAt(a,264,this.littleEndian),this.quatern_a=Math.sqrt(1-(Math.pow(this.quatern_b,2)+Math.pow(this.quatern_c,2)+Math.pow(this.quatern_d,2))),this.qoffset_x=n.Utils.getFloatAt(a,268,this.littleEndian),this.qoffset_y=n.Utils.getFloatAt(a,272,this.littleEndian),this.qoffset_z=n.Utils.getFloatAt(a,276,this.littleEndian),this.qform_code<1&&this.sform_code<1&&(this.affine[0][0]=this.pixDims[1],this.affine[1][1]=this.pixDims[2],this.affine[2][2]=this.pixDims[3]),this.qform_code>0&&this.sform_code<this.qform_code){const t=this.quatern_a,e=this.quatern_b,n=this.quatern_c,s=this.quatern_d;for(this.qfac=0===this.pixDims[0]?1:this.pixDims[0],this.quatern_R=[[t*t+e*e-n*n-s*s,2*e*n-2*t*s,2*e*s+2*t*n],[2*e*n+2*t*s,t*t+n*n-e*e-s*s,2*n*s-2*t*e],[2*e*s-2*t*n,2*n*s+2*t*e,t*t+s*s-n*n-e*e]],i=0;i<3;i+=1)for(r=0;r<3;r+=1)this.affine[i][r]=this.quatern_R[i][r]*this.pixDims[r+1],2===r&&(this.affine[i][r]*=this.qfac);this.affine[0][3]=this.qoffset_x,this.affine[1][3]=this.qoffset_y,this.affine[2][3]=this.qoffset_z}else if(this.sform_code>0)for(i=0;i<3;i+=1)for(r=0;r<4;r+=1)o=280+4*(4*i+r),this.affine[i][r]=n.Utils.getFloatAt(a,o,this.littleEndian);this.affine[3][0]=0,this.affine[3][1]=0,this.affine[3][2]=0,this.affine[3][3]=1,this.intent_name=n.Utils.getStringAt(a,328,344),this.magic=n.Utils.getStringAt(a,344,348),this.isHDR=this.magic===String.fromCharCode.apply(null,s.MAGIC_NUMBER2),a.byteLength>s.MAGIC_COOKIE&&(this.extensionFlag[0]=n.Utils.getByteAt(a,348),this.extensionFlag[1]=n.Utils.getByteAt(a,349),this.extensionFlag[2]=n.Utils.getByteAt(a,350),this.extensionFlag[3]=n.Utils.getByteAt(a,351),this.extensionFlag[0]&&(this.extensions=n.Utils.getExtensionsAt(a,this.getExtensionLocation(),this.littleEndian,this.vox_offset),this.extensionSize=this.extensions[0].esize,this.extensionCode=this.extensions[0].ecode))}toFormattedString(){var t=n.Utils.formatNumber,e="";return e+="Dim Info = "+this.dim_info+"\n",e+="Image Dimensions (1-8): "+this.dims[0]+", "+this.dims[1]+", "+this.dims[2]+", "+this.dims[3]+", "+this.dims[4]+", "+this.dims[5]+", "+this.dims[6]+", "+this.dims[7]+"\n",e+="Intent Parameters (1-3): "+this.intent_p1+", "+this.intent_p2+", "+this.intent_p3+"\n",e+="Intent Code = "+this.intent_code+"\n",e+="Datatype = "+this.datatypeCode+" ("+this.getDatatypeCodeString(this.datatypeCode)+")\n",e+="Bits Per Voxel = "+this.numBitsPerVoxel+"\n",e+="Slice Start = "+this.slice_start+"\n",e+="Voxel Dimensions (1-8): "+t(this.pixDims[0])+", "+t(this.pixDims[1])+", "+t(this.pixDims[2])+", "+t(this.pixDims[3])+", "+t(this.pixDims[4])+", "+t(this.pixDims[5])+", "+t(this.pixDims[6])+", "+t(this.pixDims[7])+"\n",e+="Image Offset = "+this.vox_offset+"\n",e+="Data Scale:  Slope = "+t(this.scl_slope)+"  Intercept = "+t(this.scl_inter)+"\n",e+="Slice End = "+this.slice_end+"\n",e+="Slice Code = "+this.slice_code+"\n",e+="Units Code = "+this.xyzt_units+" ("+this.getUnitsCodeString(s.SPATIAL_UNITS_MASK&this.xyzt_units)+", "+this.getUnitsCodeString(s.TEMPORAL_UNITS_MASK&this.xyzt_units)+")\n",e+="Display Range:  Max = "+t(this.cal_max)+"  Min = "+t(this.cal_min)+"\n",e+="Slice Duration = "+this.slice_duration+"\n",e+="Time Axis Shift = "+this.toffset+"\n",e+='Description: "'+this.description+'"\n',e+='Auxiliary File: "'+this.aux_file+'"\n',e+="Q-Form Code = "+this.qform_code+" ("+this.getTransformCodeString(this.qform_code)+")\n",e+="S-Form Code = "+this.sform_code+" ("+this.getTransformCodeString(this.sform_code)+")\n",e+="Quaternion Parameters:  b = "+t(this.quatern_b)+"  c = "+t(this.quatern_c)+"  d = "+t(this.quatern_d)+"\n",e+="Quaternion Offsets:  x = "+this.qoffset_x+"  y = "+this.qoffset_y+"  z = "+this.qoffset_z+"\n",e+="S-Form Parameters X: "+t(this.affine[0][0])+", "+t(this.affine[0][1])+", "+t(this.affine[0][2])+", "+t(this.affine[0][3])+"\n",e+="S-Form Parameters Y: "+t(this.affine[1][0])+", "+t(this.affine[1][1])+", "+t(this.affine[1][2])+", "+t(this.affine[1][3])+"\n",e+="S-Form Parameters Z: "+t(this.affine[2][0])+", "+t(this.affine[2][1])+", "+t(this.affine[2][2])+", "+t(this.affine[2][3])+"\n",e+='Intent Name: "'+this.intent_name+'"\n',this.extensionFlag[0]&&(e+="Extension: Size = "+this.extensionSize+"  Code = "+this.extensionCode+"\n"),e}getDatatypeCodeString=function(t){return t===s.TYPE_UINT8?"1-Byte Unsigned Integer":t===s.TYPE_INT16?"2-Byte Signed Integer":t===s.TYPE_INT32?"4-Byte Signed Integer":t===s.TYPE_FLOAT32?"4-Byte Float":t===s.TYPE_FLOAT64?"8-Byte Float":t===s.TYPE_RGB24?"RGB":t===s.TYPE_INT8?"1-Byte Signed Integer":t===s.TYPE_UINT16?"2-Byte Unsigned Integer":t===s.TYPE_UINT32?"4-Byte Unsigned Integer":t===s.TYPE_INT64?"8-Byte Signed Integer":t===s.TYPE_UINT64?"8-Byte Unsigned Integer":"Unknown"};getTransformCodeString=function(t){return t===s.XFORM_SCANNER_ANAT?"Scanner":t===s.XFORM_ALIGNED_ANAT?"Aligned":t===s.XFORM_TALAIRACH?"Talairach":t===s.XFORM_MNI_152?"MNI":"Unknown"};getUnitsCodeString=function(t){return t===s.UNITS_METER?"Meters":t===s.UNITS_MM?"Millimeters":t===s.UNITS_MICRON?"Microns":t===s.UNITS_SEC?"Seconds":t===s.UNITS_MSEC?"Milliseconds":t===s.UNITS_USEC?"Microseconds":t===s.UNITS_HZ?"Hz":t===s.UNITS_PPM?"PPM":t===s.UNITS_RADS?"Rads":"Unknown"};getQformMat(){return this.convertNiftiQFormToNiftiSForm(this.quatern_b,this.quatern_c,this.quatern_d,this.qoffset_x,this.qoffset_y,this.qoffset_z,this.pixDims[1],this.pixDims[2],this.pixDims[3],this.pixDims[0])}convertNiftiQFormToNiftiSForm(t,e,i,n,s,r,o,a,l,h){var f,c,u,d,p=[[0,0,0,0],[0,0,0,0],[0,0,0,0],[0,0,0,0]],g=t,m=e,_=i;return p[3][0]=p[3][1]=p[3][2]=0,p[3][3]=1,(f=1-(g*g+m*m+_*_))<1e-7?(g*=f=1/Math.sqrt(g*g+m*m+_*_),m*=f,_*=f,f=0):f=Math.sqrt(f),c=o>0?o:1,u=a>0?a:1,d=l>0?l:1,h<0&&(d=-d),p[0][0]=(f*f+g*g-m*m-_*_)*c,p[0][1]=2*(g*m-f*_)*u,p[0][2]=2*(g*_+f*m)*d,p[1][0]=2*(g*m+f*_)*c,p[1][1]=(f*f+m*m-g*g-_*_)*u,p[1][2]=2*(m*_-f*g)*d,p[2][0]=2*(g*_-f*m)*c,p[2][1]=2*(m*_+f*g)*u,p[2][2]=(f*f+_*_-m*m-g*g)*d,p[0][3]=n,p[1][3]=s,p[2][3]=r,p}convertNiftiSFormToNEMA(t){var e,i,n,s,r,o,a,l,h,f,c,u,d,p,g,m,_,v,I,y,E,A,b,T,U,x,N,S,F,w,M,C,O;if(p=0,x=[[0,0,0],[0,0,0],[0,0,0]],N=[[0,0,0],[0,0,0],[0,0,0]],e=t[0][0],i=t[0][1],n=t[0][2],s=t[1][0],r=t[1][1],o=t[1][2],a=t[2][0],l=t[2][1],h=t[2][2],0===(f=Math.sqrt(e*e+s*s+a*a)))return null;if(e/=f,s/=f,a/=f,0===(f=Math.sqrt(i*i+r*r+l*l)))return null;if(f=e*(i/=f)+s*(r/=f)+a*(l/=f),Math.abs(f)>1e-4){if(i-=f*e,r-=f*s,l-=f*a,0===(f=Math.sqrt(i*i+r*r+l*l)))return null;i/=f,r/=f,l/=f}if(0===(f=Math.sqrt(n*n+o*o+h*h))?(n=s*l-a*r,o=a*i-l*e,h=e*r-s*i):(n/=f,o/=f,h/=f),f=e*n+s*o+a*h,Math.abs(f)>1e-4){if(n-=f*e,o-=f*s,h-=f*a,0===(f=Math.sqrt(n*n+o*o+h*h)))return null;n/=f,o/=f,h/=f}if(f=i*n+r*o+l*h,Math.abs(f)>1e-4){if(n-=f*i,o-=f*r,h-=f*l,0===(f=Math.sqrt(n*n+o*o+h*h)))return null;n/=f,o/=f,h/=f}if(x[0][0]=e,x[0][1]=i,x[0][2]=n,x[1][0]=s,x[1][1]=r,x[1][2]=o,x[2][0]=a,x[2][1]=l,x[2][2]=h,0===(c=this.nifti_mat33_determ(x)))return null;for(U=-666,v=E=A=b=1,I=2,y=3,u=1;u<=3;u+=1)for(d=1;d<=3;d+=1)if(u!==d)for(p=1;p<=3;p+=1)if(u!==p&&d!==p)for(N[0][0]=N[0][1]=N[0][2]=N[1][0]=N[1][1]=N[1][2]=N[2][0]=N[2][1]=N[2][2]=0,g=-1;g<=1;g+=2)for(m=-1;m<=1;m+=2)for(_=-1;_<=1;_+=2)N[0][u-1]=g,N[1][d-1]=m,N[2][p-1]=_,this.nifti_mat33_determ(N)*c>0&&(f=(T=this.nifti_mat33_mul(N,x))[0][0]+T[1][1]+T[2][2])>U&&(U=f,v=u,I=d,y=p,E=g,A=m,b=_);switch(S=F=w=M=C=O="",v*E){case 1:S="X",M="+";break;case-1:S="X",M="-";break;case 2:S="Y",M="+";break;case-2:S="Y",M="-";break;case 3:S="Z",M="+";break;case-3:S="Z",M="-"}switch(I*A){case 1:F="X",C="+";break;case-1:F="X",C="-";break;case 2:F="Y",C="+";break;case-2:F="Y",C="-";break;case 3:F="Z",C="+";break;case-3:F="Z",C="-"}switch(y*b){case 1:w="X",O="+";break;case-1:w="X",O="-";break;case 2:w="Y",O="+";break;case-2:w="Y",O="-";break;case 3:w="Z",O="+";break;case-3:w="Z",O="-"}return S+F+w+M+C+O}nifti_mat33_mul=function(t,e){var i,n,s=[[0,0,0],[0,0,0],[0,0,0]];for(i=0;i<3;i+=1)for(n=0;n<3;n+=1)s[i][n]=t[i][0]*e[0][n]+t[i][1]*e[1][n]+t[i][2]*e[2][n];return s};nifti_mat33_determ=function(t){var e,i,n,s,r,o,a,l,h;return e=t[0][0],i=t[0][1],n=t[0][2],s=t[1][0],r=t[1][1],o=t[1][2],a=t[2][0],l=t[2][1],e*r*(h=t[2][2])-e*l*o-s*i*h+s*l*n+a*i*o-a*r*n};getExtensionLocation(){return s.MAGIC_COOKIE+4}getExtensionSize(t){return n.Utils.getIntAt(t,this.getExtensionLocation(),this.littleEndian)}getExtensionCode(t){return n.Utils.getIntAt(t,this.getExtensionLocation()+4,this.littleEndian)}addExtension(t,e=-1){-1==e?this.extensions.push(t):this.extensions.splice(e,0,t),this.vox_offset+=t.esize}removeExtension(t){let e=this.extensions[t];e&&(this.vox_offset-=e.esize),this.extensions.splice(t,1)}toArrayBuffer(t=!1){let e=352;if(t)for(let t of this.extensions)e+=t.esize;let i=new Uint8Array(e),n=new DataView(i.buffer);n.setInt32(0,348,this.littleEndian),n.setUint8(39,this.dim_info);for(let t=0;t<8;t++)n.setUint16(40+2*t,this.dims[t],this.littleEndian);n.setFloat32(56,this.intent_p1,this.littleEndian),n.setFloat32(60,this.intent_p2,this.littleEndian),n.setFloat32(64,this.intent_p3,this.littleEndian),n.setInt16(68,this.intent_code,this.littleEndian),n.setInt16(70,this.datatypeCode,this.littleEndian),n.setInt16(72,this.numBitsPerVoxel,this.littleEndian),n.setInt16(74,this.slice_start,this.littleEndian);for(let t=0;t<8;t++)n.setFloat32(76+4*t,this.pixDims[t],this.littleEndian);n.setFloat32(108,this.vox_offset,this.littleEndian),n.setFloat32(112,this.scl_slope,this.littleEndian),n.setFloat32(116,this.scl_inter,this.littleEndian),n.setInt16(120,this.slice_end,this.littleEndian),n.setUint8(122,this.slice_code),n.setUint8(123,this.xyzt_units),n.setFloat32(124,this.cal_max,this.littleEndian),n.setFloat32(128,this.cal_min,this.littleEndian),n.setFloat32(132,this.slice_duration,this.littleEndian),n.setFloat32(136,this.toffset,this.littleEndian),i.set(Buffer.from(this.description),148),i.set(Buffer.from(this.aux_file),228),n.setInt16(252,this.qform_code,this.littleEndian),n.setInt16(254,this.sform_code,this.littleEndian),n.setFloat32(256,this.quatern_b,this.littleEndian),n.setFloat32(260,this.quatern_c,this.littleEndian),n.setFloat32(264,this.quatern_d,this.littleEndian),n.setFloat32(268,this.qoffset_x,this.littleEndian),n.setFloat32(272,this.qoffset_y,this.littleEndian),n.setFloat32(276,this.qoffset_z,this.littleEndian);const s=this.affine.flat();for(let t=0;t<12;t++)n.setFloat32(280+4*t,s[t],this.littleEndian);if(i.set(Buffer.from(this.intent_name),328),i.set(Buffer.from(this.magic),344),t){i.set(Uint8Array.from([1,0,0,0]),348);let t=this.getExtensionLocation();for(const e of this.extensions)n.setInt32(t,e.esize,e.littleEndian),n.setInt32(t+4,e.ecode,e.littleEndian),i.set(new Uint8Array(e.edata),t+8),t+=e.esize}else i.set(new Uint8Array(4).fill(0),348);return i.buffer}}e.NIFTI1=s},103:(t,e,i)=>{Object.defineProperty(e,"__esModule",{value:!0}),e.NIFTI2=void 0;const n=i(232),s=i(517);class r{littleEndian=!1;dim_info=0;dims=[];intent_p1=0;intent_p2=0;intent_p3=0;intent_code=0;datatypeCode=0;numBitsPerVoxel=0;slice_start=0;slice_end=0;slice_code=0;pixDims=[];vox_offset=0;scl_slope=1;scl_inter=0;xyzt_units=0;cal_max=0;cal_min=0;slice_duration=0;toffset=0;description="";aux_file="";intent_name="";qform_code=0;sform_code=0;quatern_b=0;quatern_c=0;quatern_d=0;qoffset_x=0;qoffset_y=0;qoffset_z=0;affine=[[1,0,0,0],[0,1,0,0],[0,0,1,0],[0,0,0,1]];magic="0";extensionFlag=[0,0,0,0];extensions=[];extensionSize=0;extensionCode=0;static MAGIC_COOKIE=540;static MAGIC_NUMBER_LOCATION=4;static MAGIC_NUMBER=[110,43,50,0,13,10,26,10];static MAGIC_NUMBER2=[110,105,50,0,13,10,26,10];readHeader(t){var e,i,n,o,a=new DataView(t),l=s.Utils.getIntAt(a,0,this.littleEndian);if(l!==r.MAGIC_COOKIE&&(this.littleEndian=!0,l=s.Utils.getIntAt(a,0,this.littleEndian)),l!==r.MAGIC_COOKIE)throw new Error("This does not appear to be a NIFTI file!");for(this.magic=s.Utils.getStringAt(a,4,12),this.datatypeCode=s.Utils.getShortAt(a,12,this.littleEndian),this.numBitsPerVoxel=s.Utils.getShortAt(a,14,this.littleEndian),e=0;e<8;e+=1)o=16+8*e,this.dims[e]=s.Utils.getLongAt(a,o,this.littleEndian);for(this.intent_p1=s.Utils.getDoubleAt(a,80,this.littleEndian),this.intent_p2=s.Utils.getDoubleAt(a,88,this.littleEndian),this.intent_p3=s.Utils.getDoubleAt(a,96,this.littleEndian),e=0;e<8;e+=1)o=104+8*e,this.pixDims[e]=s.Utils.getDoubleAt(a,o,this.littleEndian);for(this.vox_offset=s.Utils.getLongAt(a,168,this.littleEndian),this.scl_slope=s.Utils.getDoubleAt(a,176,this.littleEndian),this.scl_inter=s.Utils.getDoubleAt(a,184,this.littleEndian),this.cal_max=s.Utils.getDoubleAt(a,192,this.littleEndian),this.cal_min=s.Utils.getDoubleAt(a,200,this.littleEndian),this.slice_duration=s.Utils.getDoubleAt(a,208,this.littleEndian),this.toffset=s.Utils.getDoubleAt(a,216,this.littleEndian),this.slice_start=s.Utils.getLongAt(a,224,this.littleEndian),this.slice_end=s.Utils.getLongAt(a,232,this.littleEndian),this.description=s.Utils.getStringAt(a,240,320),this.aux_file=s.Utils.getStringAt(a,320,344),this.qform_code=s.Utils.getIntAt(a,344,this.littleEndian),this.sform_code=s.Utils.getIntAt(a,348,this.littleEndian),this.quatern_b=s.Utils.getDoubleAt(a,352,this.littleEndian),this.quatern_c=s.Utils.getDoubleAt(a,360,this.littleEndian),this.quatern_d=s.Utils.getDoubleAt(a,368,this.littleEndian),this.qoffset_x=s.Utils.getDoubleAt(a,376,this.littleEndian),this.qoffset_y=s.Utils.getDoubleAt(a,384,this.littleEndian),this.qoffset_z=s.Utils.getDoubleAt(a,392,this.littleEndian),i=0;i<3;i+=1)for(n=0;n<4;n+=1)o=400+8*(4*i+n),this.affine[i][n]=s.Utils.getDoubleAt(a,o,this.littleEndian);this.affine[3][0]=0,this.affine[3][1]=0,this.affine[3][2]=0,this.affine[3][3]=1,this.slice_code=s.Utils.getIntAt(a,496,this.littleEndian),this.xyzt_units=s.Utils.getIntAt(a,500,this.littleEndian),this.intent_code=s.Utils.getIntAt(a,504,this.littleEndian),this.intent_name=s.Utils.getStringAt(a,508,524),this.dim_info=s.Utils.getByteAt(a,524),a.byteLength>r.MAGIC_COOKIE&&(this.extensionFlag[0]=s.Utils.getByteAt(a,540),this.extensionFlag[1]=s.Utils.getByteAt(a,541),this.extensionFlag[2]=s.Utils.getByteAt(a,542),this.extensionFlag[3]=s.Utils.getByteAt(a,543),this.extensionFlag[0]&&(this.extensions=s.Utils.getExtensionsAt(a,this.getExtensionLocation(),this.littleEndian,this.vox_offset),this.extensionSize=this.extensions[0].esize,this.extensionCode=this.extensions[0].ecode))}toFormattedString(){var t=s.Utils.formatNumber,e="";return e+="Datatype = "+ +this.datatypeCode+" ("+this.getDatatypeCodeString(this.datatypeCode)+")\n",e+="Bits Per Voxel =  = "+this.numBitsPerVoxel+"\n",e+="Image Dimensions (1-8): "+this.dims[0]+", "+this.dims[1]+", "+this.dims[2]+", "+this.dims[3]+", "+this.dims[4]+", "+this.dims[5]+", "+this.dims[6]+", "+this.dims[7]+"\n",e+="Intent Parameters (1-3): "+this.intent_p1+", "+this.intent_p2+", "+this.intent_p3+"\n",e+="Voxel Dimensions (1-8): "+t(this.pixDims[0])+", "+t(this.pixDims[1])+", "+t(this.pixDims[2])+", "+t(this.pixDims[3])+", "+t(this.pixDims[4])+", "+t(this.pixDims[5])+", "+t(this.pixDims[6])+", "+t(this.pixDims[7])+"\n",e+="Image Offset = "+this.vox_offset+"\n",e+="Data Scale:  Slope = "+t(this.scl_slope)+"  Intercept = "+t(this.scl_inter)+"\n",e+="Display Range:  Max = "+t(this.cal_max)+"  Min = "+t(this.cal_min)+"\n",e+="Slice Duration = "+this.slice_duration+"\n",e+="Time Axis Shift = "+this.toffset+"\n",e+="Slice Start = "+this.slice_start+"\n",e+="Slice End = "+this.slice_end+"\n",e+='Description: "'+this.description+'"\n',e+='Auxiliary File: "'+this.aux_file+'"\n',e+="Q-Form Code = "+this.qform_code+" ("+this.getTransformCodeString(this.qform_code)+")\n",e+="S-Form Code = "+this.sform_code+" ("+this.getTransformCodeString(this.sform_code)+")\n",e+="Quaternion Parameters:  b = "+t(this.quatern_b)+"  c = "+t(this.quatern_c)+"  d = "+t(this.quatern_d)+"\n",e+="Quaternion Offsets:  x = "+this.qoffset_x+"  y = "+this.qoffset_y+"  z = "+this.qoffset_z+"\n",e+="S-Form Parameters X: "+t(this.affine[0][0])+", "+t(this.affine[0][1])+", "+t(this.affine[0][2])+", "+t(this.affine[0][3])+"\n",e+="S-Form Parameters Y: "+t(this.affine[1][0])+", "+t(this.affine[1][1])+", "+t(this.affine[1][2])+", "+t(this.affine[1][3])+"\n",e+="S-Form Parameters Z: "+t(this.affine[2][0])+", "+t(this.affine[2][1])+", "+t(this.affine[2][2])+", "+t(this.affine[2][3])+"\n",e+="Slice Code = "+this.slice_code+"\n",e+="Units Code = "+this.xyzt_units+" ("+this.getUnitsCodeString(n.NIFTI1.SPATIAL_UNITS_MASK&this.xyzt_units)+", "+this.getUnitsCodeString(n.NIFTI1.TEMPORAL_UNITS_MASK&this.xyzt_units)+")\n",e+="Intent Code = "+this.intent_code+"\n",(e+='Intent Name: "'+this.intent_name+'"\n')+"Dim Info = "+this.dim_info+"\n"}getExtensionLocation=function(){return r.MAGIC_COOKIE+4};getExtensionSize=n.NIFTI1.prototype.getExtensionSize;getExtensionCode=n.NIFTI1.prototype.getExtensionCode;addExtension=n.NIFTI1.prototype.addExtension;removeExtension=n.NIFTI1.prototype.removeExtension;getDatatypeCodeString=n.NIFTI1.prototype.getDatatypeCodeString;getTransformCodeString=n.NIFTI1.prototype.getTransformCodeString;getUnitsCodeString=n.NIFTI1.prototype.getUnitsCodeString;getQformMat=n.NIFTI1.prototype.getQformMat;convertNiftiQFormToNiftiSForm=n.NIFTI1.prototype.convertNiftiQFormToNiftiSForm;convertNiftiSFormToNEMA=n.NIFTI1.prototype.convertNiftiSFormToNEMA;nifti_mat33_mul=n.NIFTI1.prototype.nifti_mat33_mul;nifti_mat33_determ=n.NIFTI1.prototype.nifti_mat33_determ;toArrayBuffer(t=!1){let e=544;if(t)for(let t of this.extensions)e+=t.esize;let i=new Uint8Array(e),n=new DataView(i.buffer);n.setInt32(0,540,this.littleEndian),i.set(Buffer.from(this.magic),4),n.setInt16(12,this.datatypeCode,this.littleEndian),n.setInt16(14,this.numBitsPerVoxel,this.littleEndian);for(let t=0;t<8;t++)n.setBigInt64(16+8*t,BigInt(this.dims[t]),this.littleEndian);n.setFloat64(80,this.intent_p1,this.littleEndian),n.setFloat64(88,this.intent_p2,this.littleEndian),n.setFloat64(96,this.intent_p3,this.littleEndian);for(let t=0;t<8;t++)n.setFloat64(104+8*t,this.pixDims[t],this.littleEndian);n.setBigInt64(168,BigInt(this.vox_offset),this.littleEndian),n.setFloat64(176,this.scl_slope,this.littleEndian),n.setFloat64(184,this.scl_inter,this.littleEndian),n.setFloat64(192,this.cal_max,this.littleEndian),n.setFloat64(200,this.cal_min,this.littleEndian),n.setFloat64(208,this.slice_duration,this.littleEndian),n.setFloat64(216,this.toffset,this.littleEndian),n.setBigInt64(224,BigInt(this.slice_start),this.littleEndian),n.setBigInt64(232,BigInt(this.slice_end),this.littleEndian),i.set(Buffer.from(this.description),240),i.set(Buffer.from(this.aux_file),320),n.setInt32(344,this.qform_code,this.littleEndian),n.setInt32(348,this.sform_code,this.littleEndian),n.setFloat64(352,this.quatern_b,this.littleEndian),n.setFloat64(360,this.quatern_c,this.littleEndian),n.setFloat64(368,this.quatern_d,this.littleEndian),n.setFloat64(376,this.qoffset_x,this.littleEndian),n.setFloat64(384,this.qoffset_y,this.littleEndian),n.setFloat64(392,this.qoffset_z,this.littleEndian);const s=this.affine.flat();for(let t=0;t<12;t++)n.setFloat64(400+8*t,s[t],this.littleEndian);if(n.setInt32(496,this.slice_code,this.littleEndian),n.setInt32(500,this.xyzt_units,this.littleEndian),n.setInt32(504,this.intent_code,this.littleEndian),i.set(Buffer.from(this.intent_name),508),n.setUint8(524,this.dim_info),t){i.set(Uint8Array.from([1,0,0,0]),540);let t=this.getExtensionLocation();for(const e of this.extensions)n.setInt32(t,e.esize,e.littleEndian),n.setInt32(t+4,e.ecode,e.littleEndian),i.set(new Uint8Array(e.edata),t+8),t+=e.esize}else i.set(new Uint8Array(4).fill(0),540);return i.buffer}}e.NIFTI2=r},517:(t,e,i)=>{Object.defineProperty(e,"__esModule",{value:!0}),e.Utils=void 0;const n=i(237);class s{static crcTable=null;static GUNZIP_MAGIC_COOKIE1=31;static GUNZIP_MAGIC_COOKIE2=139;static getStringAt(t,e,i){var n,s,r="";for(n=e;n<i;n+=1)0!==(s=t.getUint8(n))&&(r+=String.fromCharCode(s));return r}static getByteAt=function(t,e){return t.getInt8(e)};static getShortAt=function(t,e,i){return t.getInt16(e,i)};static getIntAt(t,e,i){return t.getInt32(e,i)}static getFloatAt(t,e,i){return t.getFloat32(e,i)}static getDoubleAt(t,e,i){return t.getFloat64(e,i)}static getLongAt(t,e,i){var n,r=[],o=0;for(n=0;n<8;n+=1)r[n]=s.getByteAt(t,e+n);for(n=r.length-1;n>=0;n--)o=256*o+r[n];return o}static getExtensionsAt(t,e,i,r){let o=[],a=e;for(;a<r;){let e=i,l=s.getIntAt(t,a,i);if(!l)break;if(l+a>r&&(e=!e,l=s.getIntAt(t,a,e),l+a>r))throw new Error("This does not appear to be a valid NIFTI extension");if(l%16!=0)throw new Error("This does not appear to be a NIFTI extension");let h=s.getIntAt(t,a+4,e),f=t.buffer.slice(a+8,a+l);console.log("extensionByteIndex: "+(a+8)+" esize: "+l),console.log(f);let c=new n.NIFTIEXTENSION(l,h,f,e);o.push(c),a+=l}return o}static toArrayBuffer(t){var e,i,n;for(e=new ArrayBuffer(t.length),i=new Uint8Array(e),n=0;n<t.length;n+=1)i[n]=t[n];return e}static isString(t){return"string"==typeof t||t instanceof String}static formatNumber(t,e=void 0){let i;return i=s.isString(t)?Number(t):t,i=e?i.toPrecision(5):i.toPrecision(7),parseFloat(i)}static makeCRCTable(){let t,e=[];for(var i=0;i<256;i++){t=i;for(var n=0;n<8;n++)t=1&t?3988292384^t>>>1:t>>>1;e[i]=t}return e}static crc32(t){s.crcTable||(s.crcTable=s.makeCRCTable());const e=s.crcTable;let i=-1;for(var n=0;n<t.byteLength;n++)i=i>>>8^e[255&(i^t.getUint8(n))];return(-1^i)>>>0}}e.Utils=s},953:e=>{e.exports=t},976:t=>{t.exports=e},471:(t,e)=>{Object.defineProperty(e,"__esModule",{value:!0});var i={},n=function(t,e,n,s,r){var o=new Worker(i[e]||(i[e]=URL.createObjectURL(new Blob([t+';addEventListener("error",function(e){e=e.error;postMessage({$e$:[e.message,e.code,e.stack]})})'],{type:"text/javascript"}))));return o.onmessage=function(t){var e=t.data,i=e.$e$;if(i){var n=new Error(i[0]);n.code=i[1],n.stack=i[2],r(n,null)}else r(null,e)},o.postMessage(n,s),o},s=Uint8Array,r=Uint16Array,o=Int32Array,a=new s([0,0,0,0,0,0,0,0,1,1,1,1,2,2,2,2,3,3,3,3,4,4,4,4,5,5,5,5,0,0,0,0]),l=new s([0,0,0,0,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,13,13,0,0]),h=new s([16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15]),f=function(t,e){for(var i=new r(31),n=0;n<31;++n)i[n]=e+=1<<t[n-1];var s=new o(i[30]);for(n=1;n<30;++n)for(var a=i[n];a<i[n+1];++a)s[a]=a-i[n]<<5|n;return{b:i,r:s}},c=f(a,2),u=c.b,d=c.r;u[28]=258,d[258]=28;for(var p=f(l,0),g=p.b,m=p.r,_=new r(32768),v=0;v<32768;++v){var I=(43690&v)>>1|(21845&v)<<1;I=(61680&(I=(52428&I)>>2|(13107&I)<<2))>>4|(3855&I)<<4,_[v]=((65280&I)>>8|(255&I)<<8)>>1}var y=function(t,e,i){for(var n=t.length,s=0,o=new r(e);s<n;++s)t[s]&&++o[t[s]-1];var a,l=new r(e);for(s=1;s<e;++s)l[s]=l[s-1]+o[s-1]<<1;if(i){a=new r(1<<e);var h=15-e;for(s=0;s<n;++s)if(t[s])for(var f=s<<4|t[s],c=e-t[s],u=l[t[s]-1]++<<c,d=u|(1<<c)-1;u<=d;++u)a[_[u]>>h]=f}else for(a=new r(n),s=0;s<n;++s)t[s]&&(a[s]=_[l[t[s]-1]++]>>15-t[s]);return a},E=new 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