@cornerstonejs/nifti-volume-loader 1.30.0 → 1.31.0

package/dist/umd/index.js

@@ -1,3 +1,2 @@
-/*! For license information please see index.js.LICENSE.txt */
-!function(t,e){"object"==typeof exports&&"object"==typeof module?module.exports=e(require("@cornerstonejs/core"),require("gl-matrix")):"function"==typeof define&&define.amd?define(["@cornerstonejs/core","gl-matrix"],e):"object"==typeof exports?exports.cornerstoneNiftiVolumeLoader=e(require("@cornerstonejs/core"),require("gl-matrix")):t.cornerstoneNiftiVolumeLoader=e(t.cornerstone3D,t.window)}(self,(function(t,e){return function(){var n={237:function(t,e){"use strict";Object.defineProperty(e,"__esModule",{value:!0}),e.NIFTIEXTENSION=void 0,e.NIFTIEXTENSION=class{esize;ecode;edata;littleEndian;constructor(t,e,n,i){if(t%16!=0)throw new Error("This does not appear to be a NIFTI extension");this.esize=t,this.ecode=e,this.edata=n,this.littleEndian=i}toArrayBuffer(){let t=new Uint8Array(this.esize),e=new Uint8Array(this.edata);t.set(e,8);let n=new DataView(t.buffer);return n.setInt32(0,this.esize,this.littleEndian),n.setInt32(4,this.ecode,this.littleEndian),t.buffer}}},130:function(t,e,n){"use strict";var i=this&&this.__createBinding||(Object.create?function(t,e,n,i){void 0===i&&(i=n);var r=Object.getOwnPropertyDescriptor(e,n);r&&!("get"in r?!e.__esModule:r.writable||r.configurable)||(r={enumerable:!0,get:function(){return e[n]}}),Object.defineProperty(t,i,r)}:function(t,e,n,i){void 0===i&&(i=n),t[i]=e[n]}),r=this&&this.__setModuleDefault||(Object.create?function(t,e){Object.defineProperty(t,"default",{enumerable:!0,value:e})}:function(t,e){t.default=e}),s=this&&this.__importStar||function(t){if(t&&t.__esModule)return t;var e={};if(null!=t)for(var n in t)"default"!==n&&Object.prototype.hasOwnProperty.call(t,n)&&i(e,t,n);return r(e,t),e};Object.defineProperty(e,"__esModule",{value:!0}),e.readExtensionData=e.readExtension=e.readImage=e.hasExtension=e.readHeader=e.decompress=e.isCompressed=e.isNIFTI=e.isNIFTI2=e.isNIFTI1=e.NIFTIEXTENSION=e.Utils=e.NIFTI2=e.NIFTI1=void 0;const o=s(n(876)),a=n(232),l=n(103),f=n(517);var h=n(232);Object.defineProperty(e,"NIFTI1",{enumerable:!0,get:function(){return h.NIFTI1}});var u=n(103);Object.defineProperty(e,"NIFTI2",{enumerable:!0,get:function(){return u.NIFTI2}});var c=n(517);Object.defineProperty(e,"Utils",{enumerable:!0,get:function(){return c.Utils}});var d=n(237);function p(t,e=!1){var n,i,r,s;return!(t.byteLength<a.NIFTI1.STANDARD_HEADER_SIZE||((n=new DataView(t))&&(i=n.getUint8(a.NIFTI1.MAGIC_NUMBER_LOCATION)),r=n.getUint8(a.NIFTI1.MAGIC_NUMBER_LOCATION+1),s=n.getUint8(a.NIFTI1.MAGIC_NUMBER_LOCATION+2),!(e&&i===a.NIFTI1.MAGIC_NUMBER2[0]&&r===a.NIFTI1.MAGIC_NUMBER2[1]&&s===a.NIFTI1.MAGIC_NUMBER2[2]||i===a.NIFTI1.MAGIC_NUMBER[0]&&r===a.NIFTI1.MAGIC_NUMBER[1]&&s===a.NIFTI1.MAGIC_NUMBER[2])))}function g(t,e=!1){var n,i,r,s;return!(t.byteLength<a.NIFTI1.STANDARD_HEADER_SIZE||(i=(n=new DataView(t)).getUint8(l.NIFTI2.MAGIC_NUMBER_LOCATION),r=n.getUint8(l.NIFTI2.MAGIC_NUMBER_LOCATION+1),s=n.getUint8(l.NIFTI2.MAGIC_NUMBER_LOCATION+2),!(e&&i===l.NIFTI2.MAGIC_NUMBER2[0]&&r===l.NIFTI2.MAGIC_NUMBER2[1]&&s===l.NIFTI2.MAGIC_NUMBER2[2]||i===l.NIFTI2.MAGIC_NUMBER[0]&&r===l.NIFTI2.MAGIC_NUMBER[1]&&s===l.NIFTI2.MAGIC_NUMBER[2])))}function v(t){var e,n,i;if(t){if(n=(e=new DataView(t)).getUint8(0),i=e.getUint8(1),n===f.Utils.GUNZIP_MAGIC_COOKIE1)return!0;if(i===f.Utils.GUNZIP_MAGIC_COOKIE2)return!0}return!1}function m(t){return o.decompressSync(new Uint8Array(t)).buffer}Object.defineProperty(e,"NIFTIEXTENSION",{enumerable:!0,get:function(){return d.NIFTIEXTENSION}}),e.isNIFTI1=p,e.isNIFTI2=g,e.isNIFTI=function(t,e=!1){return p(t,e)||g(t,e)},e.isCompressed=v,e.decompress=m,e.readHeader=function(t,e=!1){var n=null;return v(t)&&(t=m(t)),p(t,e)?n=new a.NIFTI1:g(t,e)&&(n=new l.NIFTI2),n?n.readHeader(t):console.error("That file does not appear to be NIFTI!"),n},e.hasExtension=function(t){return 0!=t.extensionFlag[0]},e.readImage=function(t,e){var n=t.vox_offset,i=1,r=1;t.dims[4]&&(i=t.dims[4]),t.dims[5]&&(r=t.dims[5]);var s=t.dims[1]*t.dims[2]*t.dims[3]*i*r*(t.numBitsPerVoxel/8);return e.slice(n,n+s)},e.readExtension=function(t,e){var n=t.getExtensionLocation(),i=t.extensionSize;return e.slice(n,n+i)},e.readExtensionData=function(t,e){var n=t.getExtensionLocation(),i=t.extensionSize;return e.slice(n+8,n+i)}},232:function(t,e,n){"use strict";Object.defineProperty(e,"__esModule",{value:!0}),e.NIFTI1=void 0;const i=n(517);class r{littleEndian=!1;dim_info=0;dims=[];intent_p1=0;intent_p2=0;intent_p3=0;intent_code=0;datatypeCode=0;numBitsPerVoxel=0;slice_start=0;slice_end=0;slice_code=0;pixDims=[];vox_offset=0;scl_slope=1;scl_inter=0;xyzt_units=0;cal_max=0;cal_min=0;slice_duration=0;toffset=0;description="";aux_file="";intent_name="";qform_code=0;sform_code=0;quatern_a=0;quatern_b=0;quatern_c=0;quatern_d=0;qoffset_x=0;qoffset_y=0;qoffset_z=0;affine=[[1,0,0,0],[0,1,0,0],[0,0,1,0],[0,0,0,1]];qfac=1;quatern_R;magic="0";isHDR=!1;extensionFlag=[0,0,0,0];extensionSize=0;extensionCode=0;extensions=[];static TYPE_NONE=0;static TYPE_BINARY=1;static TYPE_UINT8=2;static TYPE_INT16=4;static TYPE_INT32=8;static TYPE_FLOAT32=16;static TYPE_COMPLEX64=32;static TYPE_FLOAT64=64;static TYPE_RGB24=128;static TYPE_INT8=256;static TYPE_UINT16=512;static TYPE_UINT32=768;static TYPE_INT64=1024;static TYPE_UINT64=1280;static TYPE_FLOAT128=1536;static TYPE_COMPLEX128=1792;static TYPE_COMPLEX256=2048;static XFORM_UNKNOWN=0;static XFORM_SCANNER_ANAT=1;static XFORM_ALIGNED_ANAT=2;static XFORM_TALAIRACH=3;static XFORM_MNI_152=4;static SPATIAL_UNITS_MASK=7;static TEMPORAL_UNITS_MASK=56;static UNITS_UNKNOWN=0;static UNITS_METER=1;static UNITS_MM=2;static UNITS_MICRON=3;static UNITS_SEC=8;static UNITS_MSEC=16;static UNITS_USEC=24;static UNITS_HZ=32;static UNITS_PPM=40;static UNITS_RADS=48;static MAGIC_COOKIE=348;static STANDARD_HEADER_SIZE=348;static MAGIC_NUMBER_LOCATION=344;static MAGIC_NUMBER=[110,43,49];static MAGIC_NUMBER2=[110,105,49];static EXTENSION_HEADER_SIZE=8;readHeader(t){var e,n,s,o,a=new DataView(t),l=i.Utils.getIntAt(a,0,this.littleEndian);if(l!==r.MAGIC_COOKIE&&(this.littleEndian=!0,l=i.Utils.getIntAt(a,0,this.littleEndian)),l!==r.MAGIC_COOKIE)throw new Error("This does not appear to be a NIFTI file!");for(this.dim_info=i.Utils.getByteAt(a,39),e=0;e<8;e+=1)o=40+2*e,this.dims[e]=i.Utils.getShortAt(a,o,this.littleEndian);for(this.intent_p1=i.Utils.getFloatAt(a,56,this.littleEndian),this.intent_p2=i.Utils.getFloatAt(a,60,this.littleEndian),this.intent_p3=i.Utils.getFloatAt(a,64,this.littleEndian),this.intent_code=i.Utils.getShortAt(a,68,this.littleEndian),this.datatypeCode=i.Utils.getShortAt(a,70,this.littleEndian),this.numBitsPerVoxel=i.Utils.getShortAt(a,72,this.littleEndian),this.slice_start=i.Utils.getShortAt(a,74,this.littleEndian),e=0;e<8;e+=1)o=76+4*e,this.pixDims[e]=i.Utils.getFloatAt(a,o,this.littleEndian);if(this.vox_offset=i.Utils.getFloatAt(a,108,this.littleEndian),this.scl_slope=i.Utils.getFloatAt(a,112,this.littleEndian),this.scl_inter=i.Utils.getFloatAt(a,116,this.littleEndian),this.slice_end=i.Utils.getShortAt(a,120,this.littleEndian),this.slice_code=i.Utils.getByteAt(a,122),this.xyzt_units=i.Utils.getByteAt(a,123),this.cal_max=i.Utils.getFloatAt(a,124,this.littleEndian),this.cal_min=i.Utils.getFloatAt(a,128,this.littleEndian),this.slice_duration=i.Utils.getFloatAt(a,132,this.littleEndian),this.toffset=i.Utils.getFloatAt(a,136,this.littleEndian),this.description=i.Utils.getStringAt(a,148,228),this.aux_file=i.Utils.getStringAt(a,228,252),this.qform_code=i.Utils.getShortAt(a,252,this.littleEndian),this.sform_code=i.Utils.getShortAt(a,254,this.littleEndian),this.quatern_b=i.Utils.getFloatAt(a,256,this.littleEndian),this.quatern_c=i.Utils.getFloatAt(a,260,this.littleEndian),this.quatern_d=i.Utils.getFloatAt(a,264,this.littleEndian),this.quatern_a=Math.sqrt(1-(Math.pow(this.quatern_b,2)+Math.pow(this.quatern_c,2)+Math.pow(this.quatern_d,2))),this.qoffset_x=i.Utils.getFloatAt(a,268,this.littleEndian),this.qoffset_y=i.Utils.getFloatAt(a,272,this.littleEndian),this.qoffset_z=i.Utils.getFloatAt(a,276,this.littleEndian),this.qform_code<1&&this.sform_code<1&&(this.affine[0][0]=this.pixDims[1],this.affine[1][1]=this.pixDims[2],this.affine[2][2]=this.pixDims[3]),this.qform_code>0&&this.sform_code<this.qform_code){const t=this.quatern_a,e=this.quatern_b,i=this.quatern_c,r=this.quatern_d;for(this.qfac=0===this.pixDims[0]?1:this.pixDims[0],this.quatern_R=[[t*t+e*e-i*i-r*r,2*e*i-2*t*r,2*e*r+2*t*i],[2*e*i+2*t*r,t*t+i*i-e*e-r*r,2*i*r-2*t*e],[2*e*r-2*t*i,2*i*r+2*t*e,t*t+r*r-i*i-e*e]],n=0;n<3;n+=1)for(s=0;s<3;s+=1)this.affine[n][s]=this.quatern_R[n][s]*this.pixDims[s+1],2===s&&(this.affine[n][s]*=this.qfac);this.affine[0][3]=this.qoffset_x,this.affine[1][3]=this.qoffset_y,this.affine[2][3]=this.qoffset_z}else if(this.sform_code>0)for(n=0;n<3;n+=1)for(s=0;s<4;s+=1)o=280+4*(4*n+s),this.affine[n][s]=i.Utils.getFloatAt(a,o,this.littleEndian);this.affine[3][0]=0,this.affine[3][1]=0,this.affine[3][2]=0,this.affine[3][3]=1,this.intent_name=i.Utils.getStringAt(a,328,344),this.magic=i.Utils.getStringAt(a,344,348),this.isHDR=this.magic===String.fromCharCode.apply(null,r.MAGIC_NUMBER2),a.byteLength>r.MAGIC_COOKIE&&(this.extensionFlag[0]=i.Utils.getByteAt(a,348),this.extensionFlag[1]=i.Utils.getByteAt(a,349),this.extensionFlag[2]=i.Utils.getByteAt(a,350),this.extensionFlag[3]=i.Utils.getByteAt(a,351),this.extensionFlag[0]&&(this.extensions=i.Utils.getExtensionsAt(a,this.getExtensionLocation(),this.littleEndian,this.vox_offset),this.extensionSize=this.extensions[0].esize,this.extensionCode=this.extensions[0].ecode))}toFormattedString(){var t=i.Utils.formatNumber,e="";return e+="Dim Info = "+this.dim_info+"\n",e+="Image Dimensions (1-8): "+this.dims[0]+", "+this.dims[1]+", "+this.dims[2]+", "+this.dims[3]+", "+this.dims[4]+", "+this.dims[5]+", "+this.dims[6]+", "+this.dims[7]+"\n",e+="Intent Parameters (1-3): "+this.intent_p1+", "+this.intent_p2+", "+this.intent_p3+"\n",e+="Intent Code = "+this.intent_code+"\n",e+="Datatype = "+this.datatypeCode+" ("+this.getDatatypeCodeString(this.datatypeCode)+")\n",e+="Bits Per Voxel = "+this.numBitsPerVoxel+"\n",e+="Slice Start = "+this.slice_start+"\n",e+="Voxel Dimensions (1-8): "+t(this.pixDims[0])+", "+t(this.pixDims[1])+", "+t(this.pixDims[2])+", "+t(this.pixDims[3])+", "+t(this.pixDims[4])+", "+t(this.pixDims[5])+", "+t(this.pixDims[6])+", "+t(this.pixDims[7])+"\n",e+="Image Offset = "+this.vox_offset+"\n",e+="Data Scale:  Slope = "+t(this.scl_slope)+"  Intercept = "+t(this.scl_inter)+"\n",e+="Slice End = "+this.slice_end+"\n",e+="Slice Code = "+this.slice_code+"\n",e+="Units Code = "+this.xyzt_units+" ("+this.getUnitsCodeString(r.SPATIAL_UNITS_MASK&this.xyzt_units)+", "+this.getUnitsCodeString(r.TEMPORAL_UNITS_MASK&this.xyzt_units)+")\n",e+="Display Range:  Max = "+t(this.cal_max)+"  Min = "+t(this.cal_min)+"\n",e+="Slice Duration = "+this.slice_duration+"\n",e+="Time Axis Shift = "+this.toffset+"\n",e+='Description: "'+this.description+'"\n',e+='Auxiliary File: "'+this.aux_file+'"\n',e+="Q-Form Code = "+this.qform_code+" ("+this.getTransformCodeString(this.qform_code)+")\n",e+="S-Form Code = "+this.sform_code+" ("+this.getTransformCodeString(this.sform_code)+")\n",e+="Quaternion Parameters:  b = "+t(this.quatern_b)+"  c = "+t(this.quatern_c)+"  d = "+t(this.quatern_d)+"\n",e+="Quaternion Offsets:  x = "+this.qoffset_x+"  y = "+this.qoffset_y+"  z = "+this.qoffset_z+"\n",e+="S-Form Parameters X: "+t(this.affine[0][0])+", "+t(this.affine[0][1])+", "+t(this.affine[0][2])+", "+t(this.affine[0][3])+"\n",e+="S-Form Parameters Y: "+t(this.affine[1][0])+", "+t(this.affine[1][1])+", "+t(this.affine[1][2])+", "+t(this.affine[1][3])+"\n",e+="S-Form Parameters Z: "+t(this.affine[2][0])+", "+t(this.affine[2][1])+", "+t(this.affine[2][2])+", "+t(this.affine[2][3])+"\n",e+='Intent Name: "'+this.intent_name+'"\n',this.extensionFlag[0]&&(e+="Extension: Size = "+this.extensionSize+"  Code = "+this.extensionCode+"\n"),e}getDatatypeCodeString=function(t){return t===r.TYPE_UINT8?"1-Byte Unsigned Integer":t===r.TYPE_INT16?"2-Byte Signed Integer":t===r.TYPE_INT32?"4-Byte Signed Integer":t===r.TYPE_FLOAT32?"4-Byte Float":t===r.TYPE_FLOAT64?"8-Byte Float":t===r.TYPE_RGB24?"RGB":t===r.TYPE_INT8?"1-Byte Signed Integer":t===r.TYPE_UINT16?"2-Byte Unsigned Integer":t===r.TYPE_UINT32?"4-Byte Unsigned Integer":t===r.TYPE_INT64?"8-Byte Signed Integer":t===r.TYPE_UINT64?"8-Byte Unsigned Integer":"Unknown"};getTransformCodeString=function(t){return t===r.XFORM_SCANNER_ANAT?"Scanner":t===r.XFORM_ALIGNED_ANAT?"Aligned":t===r.XFORM_TALAIRACH?"Talairach":t===r.XFORM_MNI_152?"MNI":"Unknown"};getUnitsCodeString=function(t){return t===r.UNITS_METER?"Meters":t===r.UNITS_MM?"Millimeters":t===r.UNITS_MICRON?"Microns":t===r.UNITS_SEC?"Seconds":t===r.UNITS_MSEC?"Milliseconds":t===r.UNITS_USEC?"Microseconds":t===r.UNITS_HZ?"Hz":t===r.UNITS_PPM?"PPM":t===r.UNITS_RADS?"Rads":"Unknown"};getQformMat(){return this.convertNiftiQFormToNiftiSForm(this.quatern_b,this.quatern_c,this.quatern_d,this.qoffset_x,this.qoffset_y,this.qoffset_z,this.pixDims[1],this.pixDims[2],this.pixDims[3],this.pixDims[0])}convertNiftiQFormToNiftiSForm(t,e,n,i,r,s,o,a,l,f){var h,u,c,d,p=[[0,0,0,0],[0,0,0,0],[0,0,0,0],[0,0,0,0]],g=t,v=e,m=n;return p[3][0]=p[3][1]=p[3][2]=0,p[3][3]=1,(h=1-(g*g+v*v+m*m))<1e-7?(g*=h=1/Math.sqrt(g*g+v*v+m*m),v*=h,m*=h,h=0):h=Math.sqrt(h),u=o>0?o:1,c=a>0?a:1,d=l>0?l:1,f<0&&(d=-d),p[0][0]=(h*h+g*g-v*v-m*m)*u,p[0][1]=2*(g*v-h*m)*c,p[0][2]=2*(g*m+h*v)*d,p[1][0]=2*(g*v+h*m)*u,p[1][1]=(h*h+v*v-g*g-m*m)*c,p[1][2]=2*(v*m-h*g)*d,p[2][0]=2*(g*m-h*v)*u,p[2][1]=2*(v*m+h*g)*c,p[2][2]=(h*h+m*m-v*v-g*g)*d,p[0][3]=i,p[1][3]=r,p[2][3]=s,p}convertNiftiSFormToNEMA(t){var e,n,i,r,s,o,a,l,f,h,u,c,d,p,g,v,m,y,_,I,E,b,x,A,w,T,N,U,S,F,M,C,O;if(p=0,T=[[0,0,0],[0,0,0],[0,0,0]],N=[[0,0,0],[0,0,0],[0,0,0]],e=t[0][0],n=t[0][1],i=t[0][2],r=t[1][0],s=t[1][1],o=t[1][2],a=t[2][0],l=t[2][1],f=t[2][2],0===(h=Math.sqrt(e*e+r*r+a*a)))return null;if(e/=h,r/=h,a/=h,0===(h=Math.sqrt(n*n+s*s+l*l)))return null;if(h=e*(n/=h)+r*(s/=h)+a*(l/=h),Math.abs(h)>1e-4){if(n-=h*e,s-=h*r,l-=h*a,0===(h=Math.sqrt(n*n+s*s+l*l)))return null;n/=h,s/=h,l/=h}if(0===(h=Math.sqrt(i*i+o*o+f*f))?(i=r*l-a*s,o=a*n-l*e,f=e*s-r*n):(i/=h,o/=h,f/=h),h=e*i+r*o+a*f,Math.abs(h)>1e-4){if(i-=h*e,o-=h*r,f-=h*a,0===(h=Math.sqrt(i*i+o*o+f*f)))return null;i/=h,o/=h,f/=h}if(h=n*i+s*o+l*f,Math.abs(h)>1e-4){if(i-=h*n,o-=h*s,f-=h*l,0===(h=Math.sqrt(i*i+o*o+f*f)))return null;i/=h,o/=h,f/=h}if(T[0][0]=e,T[0][1]=n,T[0][2]=i,T[1][0]=r,T[1][1]=s,T[1][2]=o,T[2][0]=a,T[2][1]=l,T[2][2]=f,0===(u=this.nifti_mat33_determ(T)))return null;for(w=-666,y=E=b=x=1,_=2,I=3,c=1;c<=3;c+=1)for(d=1;d<=3;d+=1)if(c!==d)for(p=1;p<=3;p+=1)if(c!==p&&d!==p)for(N[0][0]=N[0][1]=N[0][2]=N[1][0]=N[1][1]=N[1][2]=N[2][0]=N[2][1]=N[2][2]=0,g=-1;g<=1;g+=2)for(v=-1;v<=1;v+=2)for(m=-1;m<=1;m+=2)N[0][c-1]=g,N[1][d-1]=v,N[2][p-1]=m,this.nifti_mat33_determ(N)*u>0&&(h=(A=this.nifti_mat33_mul(N,T))[0][0]+A[1][1]+A[2][2])>w&&(w=h,y=c,_=d,I=p,E=g,b=v,x=m);switch(U=S=F=M=C=O="",y*E){case 1:U="X",M="+";break;case-1:U="X",M="-";break;case 2:U="Y",M="+";break;case-2:U="Y",M="-";break;case 3:U="Z",M="+";break;case-3:U="Z",M="-"}switch(_*b){case 1:S="X",C="+";break;case-1:S="X",C="-";break;case 2:S="Y",C="+";break;case-2:S="Y",C="-";break;case 3:S="Z",C="+";break;case-3:S="Z",C="-"}switch(I*x){case 1:F="X",O="+";break;case-1:F="X",O="-";break;case 2:F="Y",O="+";break;case-2:F="Y",O="-";break;case 3:F="Z",O="+";break;case-3:F="Z",O="-"}return U+S+F+M+C+O}nifti_mat33_mul=function(t,e){var n,i,r=[[0,0,0],[0,0,0],[0,0,0]];for(n=0;n<3;n+=1)for(i=0;i<3;i+=1)r[n][i]=t[n][0]*e[0][i]+t[n][1]*e[1][i]+t[n][2]*e[2][i];return r};nifti_mat33_determ=function(t){var e,n,i,r,s,o,a,l,f;return e=t[0][0],n=t[0][1],i=t[0][2],r=t[1][0],s=t[1][1],o=t[1][2],a=t[2][0],l=t[2][1],e*s*(f=t[2][2])-e*l*o-r*n*f+r*l*i+a*n*o-a*s*i};getExtensionLocation(){return r.MAGIC_COOKIE+4}getExtensionSize(t){return i.Utils.getIntAt(t,this.getExtensionLocation(),this.littleEndian)}getExtensionCode(t){return i.Utils.getIntAt(t,this.getExtensionLocation()+4,this.littleEndian)}addExtension(t,e=-1){-1==e?this.extensions.push(t):this.extensions.splice(e,0,t),this.vox_offset+=t.esize}removeExtension(t){let e=this.extensions[t];e&&(this.vox_offset-=e.esize),this.extensions.splice(t,1)}toArrayBuffer(t=!1){let e=352;if(t)for(let t of this.extensions)e+=t.esize;let n=new Uint8Array(e),i=new DataView(n.buffer);i.setInt32(0,348,this.littleEndian),i.setUint8(39,this.dim_info);for(let t=0;t<8;t++)i.setUint16(40+2*t,this.dims[t],this.littleEndian);i.setFloat32(56,this.intent_p1,this.littleEndian),i.setFloat32(60,this.intent_p2,this.littleEndian),i.setFloat32(64,this.intent_p3,this.littleEndian),i.setInt16(68,this.intent_code,this.littleEndian),i.setInt16(70,this.datatypeCode,this.littleEndian),i.setInt16(72,this.numBitsPerVoxel,this.littleEndian),i.setInt16(74,this.slice_start,this.littleEndian);for(let t=0;t<8;t++)i.setFloat32(76+4*t,this.pixDims[t],this.littleEndian);i.setFloat32(108,this.vox_offset,this.littleEndian),i.setFloat32(112,this.scl_slope,this.littleEndian),i.setFloat32(116,this.scl_inter,this.littleEndian),i.setInt16(120,this.slice_end,this.littleEndian),i.setUint8(122,this.slice_code),i.setUint8(123,this.xyzt_units),i.setFloat32(124,this.cal_max,this.littleEndian),i.setFloat32(128,this.cal_min,this.littleEndian),i.setFloat32(132,this.slice_duration,this.littleEndian),i.setFloat32(136,this.toffset,this.littleEndian),n.set(Buffer.from(this.description),148),n.set(Buffer.from(this.aux_file),228),i.setInt16(252,this.qform_code,this.littleEndian),i.setInt16(254,this.sform_code,this.littleEndian),i.setFloat32(256,this.quatern_b,this.littleEndian),i.setFloat32(260,this.quatern_c,this.littleEndian),i.setFloat32(264,this.quatern_d,this.littleEndian),i.setFloat32(268,this.qoffset_x,this.littleEndian),i.setFloat32(272,this.qoffset_y,this.littleEndian),i.setFloat32(276,this.qoffset_z,this.littleEndian);const r=this.affine.flat();for(let t=0;t<12;t++)i.setFloat32(280+4*t,r[t],this.littleEndian);if(n.set(Buffer.from(this.intent_name),328),n.set(Buffer.from(this.magic),344),t){n.set(Uint8Array.from([1,0,0,0]),348);let t=this.getExtensionLocation();for(const e of this.extensions)i.setInt32(t,e.esize,e.littleEndian),i.setInt32(t+4,e.ecode,e.littleEndian),n.set(new Uint8Array(e.edata),t+8),t+=e.esize}else n.set(new Uint8Array(4).fill(0),348);return n.buffer}}e.NIFTI1=r},103:function(t,e,n){"use strict";Object.defineProperty(e,"__esModule",{value:!0}),e.NIFTI2=void 0;const i=n(232),r=n(517);class s{littleEndian=!1;dim_info=0;dims=[];intent_p1=0;intent_p2=0;intent_p3=0;intent_code=0;datatypeCode=0;numBitsPerVoxel=0;slice_start=0;slice_end=0;slice_code=0;pixDims=[];vox_offset=0;scl_slope=1;scl_inter=0;xyzt_units=0;cal_max=0;cal_min=0;slice_duration=0;toffset=0;description="";aux_file="";intent_name="";qform_code=0;sform_code=0;quatern_b=0;quatern_c=0;quatern_d=0;qoffset_x=0;qoffset_y=0;qoffset_z=0;affine=[[1,0,0,0],[0,1,0,0],[0,0,1,0],[0,0,0,1]];magic="0";extensionFlag=[0,0,0,0];extensions=[];extensionSize=0;extensionCode=0;static MAGIC_COOKIE=540;static MAGIC_NUMBER_LOCATION=4;static MAGIC_NUMBER=[110,43,50,0,13,10,26,10];static MAGIC_NUMBER2=[110,105,50,0,13,10,26,10];readHeader(t){var e,n,i,o,a=new DataView(t),l=r.Utils.getIntAt(a,0,this.littleEndian);if(l!==s.MAGIC_COOKIE&&(this.littleEndian=!0,l=r.Utils.getIntAt(a,0,this.littleEndian)),l!==s.MAGIC_COOKIE)throw new Error("This does not appear to be a NIFTI file!");for(this.magic=r.Utils.getStringAt(a,4,12),this.datatypeCode=r.Utils.getShortAt(a,12,this.littleEndian),this.numBitsPerVoxel=r.Utils.getShortAt(a,14,this.littleEndian),e=0;e<8;e+=1)o=16+8*e,this.dims[e]=r.Utils.getLongAt(a,o,this.littleEndian);for(this.intent_p1=r.Utils.getDoubleAt(a,80,this.littleEndian),this.intent_p2=r.Utils.getDoubleAt(a,88,this.littleEndian),this.intent_p3=r.Utils.getDoubleAt(a,96,this.littleEndian),e=0;e<8;e+=1)o=104+8*e,this.pixDims[e]=r.Utils.getDoubleAt(a,o,this.littleEndian);for(this.vox_offset=r.Utils.getLongAt(a,168,this.littleEndian),this.scl_slope=r.Utils.getDoubleAt(a,176,this.littleEndian),this.scl_inter=r.Utils.getDoubleAt(a,184,this.littleEndian),this.cal_max=r.Utils.getDoubleAt(a,192,this.littleEndian),this.cal_min=r.Utils.getDoubleAt(a,200,this.littleEndian),this.slice_duration=r.Utils.getDoubleAt(a,208,this.littleEndian),this.toffset=r.Utils.getDoubleAt(a,216,this.littleEndian),this.slice_start=r.Utils.getLongAt(a,224,this.littleEndian),this.slice_end=r.Utils.getLongAt(a,232,this.littleEndian),this.description=r.Utils.getStringAt(a,240,320),this.aux_file=r.Utils.getStringAt(a,320,344),this.qform_code=r.Utils.getIntAt(a,344,this.littleEndian),this.sform_code=r.Utils.getIntAt(a,348,this.littleEndian),this.quatern_b=r.Utils.getDoubleAt(a,352,this.littleEndian),this.quatern_c=r.Utils.getDoubleAt(a,360,this.littleEndian),this.quatern_d=r.Utils.getDoubleAt(a,368,this.littleEndian),this.qoffset_x=r.Utils.getDoubleAt(a,376,this.littleEndian),this.qoffset_y=r.Utils.getDoubleAt(a,384,this.littleEndian),this.qoffset_z=r.Utils.getDoubleAt(a,392,this.littleEndian),n=0;n<3;n+=1)for(i=0;i<4;i+=1)o=400+8*(4*n+i),this.affine[n][i]=r.Utils.getDoubleAt(a,o,this.littleEndian);this.affine[3][0]=0,this.affine[3][1]=0,this.affine[3][2]=0,this.affine[3][3]=1,this.slice_code=r.Utils.getIntAt(a,496,this.littleEndian),this.xyzt_units=r.Utils.getIntAt(a,500,this.littleEndian),this.intent_code=r.Utils.getIntAt(a,504,this.littleEndian),this.intent_name=r.Utils.getStringAt(a,508,524),this.dim_info=r.Utils.getByteAt(a,524),a.byteLength>s.MAGIC_COOKIE&&(this.extensionFlag[0]=r.Utils.getByteAt(a,540),this.extensionFlag[1]=r.Utils.getByteAt(a,541),this.extensionFlag[2]=r.Utils.getByteAt(a,542),this.extensionFlag[3]=r.Utils.getByteAt(a,543),this.extensionFlag[0]&&(this.extensions=r.Utils.getExtensionsAt(a,this.getExtensionLocation(),this.littleEndian,this.vox_offset),this.extensionSize=this.extensions[0].esize,this.extensionCode=this.extensions[0].ecode))}toFormattedString(){var t=r.Utils.formatNumber,e="";return e+="Datatype = "+ +this.datatypeCode+" ("+this.getDatatypeCodeString(this.datatypeCode)+")\n",e+="Bits Per Voxel =  = "+this.numBitsPerVoxel+"\n",e+="Image Dimensions (1-8): "+this.dims[0]+", "+this.dims[1]+", "+this.dims[2]+", "+this.dims[3]+", "+this.dims[4]+", "+this.dims[5]+", "+this.dims[6]+", "+this.dims[7]+"\n",e+="Intent Parameters (1-3): "+this.intent_p1+", "+this.intent_p2+", "+this.intent_p3+"\n",e+="Voxel Dimensions (1-8): "+t(this.pixDims[0])+", "+t(this.pixDims[1])+", "+t(this.pixDims[2])+", "+t(this.pixDims[3])+", "+t(this.pixDims[4])+", "+t(this.pixDims[5])+", "+t(this.pixDims[6])+", "+t(this.pixDims[7])+"\n",e+="Image Offset = "+this.vox_offset+"\n",e+="Data Scale:  Slope = "+t(this.scl_slope)+"  Intercept = "+t(this.scl_inter)+"\n",e+="Display Range:  Max = "+t(this.cal_max)+"  Min = "+t(this.cal_min)+"\n",e+="Slice Duration = "+this.slice_duration+"\n",e+="Time Axis Shift = "+this.toffset+"\n",e+="Slice Start = "+this.slice_start+"\n",e+="Slice End = "+this.slice_end+"\n",e+='Description: "'+this.description+'"\n',e+='Auxiliary File: "'+this.aux_file+'"\n',e+="Q-Form Code = "+this.qform_code+" ("+this.getTransformCodeString(this.qform_code)+")\n",e+="S-Form Code = "+this.sform_code+" ("+this.getTransformCodeString(this.sform_code)+")\n",e+="Quaternion Parameters:  b = "+t(this.quatern_b)+"  c = "+t(this.quatern_c)+"  d = "+t(this.quatern_d)+"\n",e+="Quaternion Offsets:  x = "+this.qoffset_x+"  y = "+this.qoffset_y+"  z = "+this.qoffset_z+"\n",e+="S-Form Parameters X: "+t(this.affine[0][0])+", "+t(this.affine[0][1])+", "+t(this.affine[0][2])+", "+t(this.affine[0][3])+"\n",e+="S-Form Parameters Y: "+t(this.affine[1][0])+", "+t(this.affine[1][1])+", "+t(this.affine[1][2])+", "+t(this.affine[1][3])+"\n",e+="S-Form Parameters Z: "+t(this.affine[2][0])+", "+t(this.affine[2][1])+", "+t(this.affine[2][2])+", "+t(this.affine[2][3])+"\n",e+="Slice Code = "+this.slice_code+"\n",e+="Units Code = "+this.xyzt_units+" ("+this.getUnitsCodeString(i.NIFTI1.SPATIAL_UNITS_MASK&this.xyzt_units)+", "+this.getUnitsCodeString(i.NIFTI1.TEMPORAL_UNITS_MASK&this.xyzt_units)+")\n",e+="Intent Code = "+this.intent_code+"\n",(e+='Intent Name: "'+this.intent_name+'"\n')+"Dim Info = "+this.dim_info+"\n"}getExtensionLocation=function(){return s.MAGIC_COOKIE+4};getExtensionSize=i.NIFTI1.prototype.getExtensionSize;getExtensionCode=i.NIFTI1.prototype.getExtensionCode;addExtension=i.NIFTI1.prototype.addExtension;removeExtension=i.NIFTI1.prototype.removeExtension;getDatatypeCodeString=i.NIFTI1.prototype.getDatatypeCodeString;getTransformCodeString=i.NIFTI1.prototype.getTransformCodeString;getUnitsCodeString=i.NIFTI1.prototype.getUnitsCodeString;getQformMat=i.NIFTI1.prototype.getQformMat;convertNiftiQFormToNiftiSForm=i.NIFTI1.prototype.convertNiftiQFormToNiftiSForm;convertNiftiSFormToNEMA=i.NIFTI1.prototype.convertNiftiSFormToNEMA;nifti_mat33_mul=i.NIFTI1.prototype.nifti_mat33_mul;nifti_mat33_determ=i.NIFTI1.prototype.nifti_mat33_determ;toArrayBuffer(t=!1){let e=544;if(t)for(let t of this.extensions)e+=t.esize;let n=new Uint8Array(e),i=new DataView(n.buffer);i.setInt32(0,540,this.littleEndian),n.set(Buffer.from(this.magic),4),i.setInt16(12,this.datatypeCode,this.littleEndian),i.setInt16(14,this.numBitsPerVoxel,this.littleEndian);for(let t=0;t<8;t++)i.setBigInt64(16+8*t,BigInt(this.dims[t]),this.littleEndian);i.setFloat64(80,this.intent_p1,this.littleEndian),i.setFloat64(88,this.intent_p2,this.littleEndian),i.setFloat64(96,this.intent_p3,this.littleEndian);for(let t=0;t<8;t++)i.setFloat64(104+8*t,this.pixDims[t],this.littleEndian);i.setBigInt64(168,BigInt(this.vox_offset),this.littleEndian),i.setFloat64(176,this.scl_slope,this.littleEndian),i.setFloat64(184,this.scl_inter,this.littleEndian),i.setFloat64(192,this.cal_max,this.littleEndian),i.setFloat64(200,this.cal_min,this.littleEndian),i.setFloat64(208,this.slice_duration,this.littleEndian),i.setFloat64(216,this.toffset,this.littleEndian),i.setBigInt64(224,BigInt(this.slice_start),this.littleEndian),i.setBigInt64(232,BigInt(this.slice_end),this.littleEndian),n.set(Buffer.from(this.description),240),n.set(Buffer.from(this.aux_file),320),i.setInt32(344,this.qform_code,this.littleEndian),i.setInt32(348,this.sform_code,this.littleEndian),i.setFloat64(352,this.quatern_b,this.littleEndian),i.setFloat64(360,this.quatern_c,this.littleEndian),i.setFloat64(368,this.quatern_d,this.littleEndian),i.setFloat64(376,this.qoffset_x,this.littleEndian),i.setFloat64(384,this.qoffset_y,this.littleEndian),i.setFloat64(392,this.qoffset_z,this.littleEndian);const r=this.affine.flat();for(let t=0;t<12;t++)i.setFloat64(400+8*t,r[t],this.littleEndian);if(i.setInt32(496,this.slice_code,this.littleEndian),i.setInt32(500,this.xyzt_units,this.littleEndian),i.setInt32(504,this.intent_code,this.littleEndian),n.set(Buffer.from(this.intent_name),508),i.setUint8(524,this.dim_info),t){n.set(Uint8Array.from([1,0,0,0]),540);let t=this.getExtensionLocation();for(const e of this.extensions)i.setInt32(t,e.esize,e.littleEndian),i.setInt32(t+4,e.ecode,e.littleEndian),n.set(new Uint8Array(e.edata),t+8),t+=e.esize}else n.set(new Uint8Array(4).fill(0),540);return n.buffer}}e.NIFTI2=s},517:function(t,e,n){"use strict";Object.defineProperty(e,"__esModule",{value:!0}),e.Utils=void 0;const i=n(237);class r{static crcTable=null;static GUNZIP_MAGIC_COOKIE1=31;static GUNZIP_MAGIC_COOKIE2=139;static getStringAt(t,e,n){var i,r,s="";for(i=e;i<n;i+=1)0!==(r=t.getUint8(i))&&(s+=String.fromCharCode(r));return s}static getByteAt=function(t,e){return t.getInt8(e)};static getShortAt=function(t,e,n){return t.getInt16(e,n)};static getIntAt(t,e,n){return t.getInt32(e,n)}static getFloatAt(t,e,n){return t.getFloat32(e,n)}static getDoubleAt(t,e,n){return t.getFloat64(e,n)}static getLongAt(t,e,n){var i,s=[],o=0;for(i=0;i<8;i+=1)s[i]=r.getByteAt(t,e+i);for(i=s.length-1;i>=0;i--)o=256*o+s[i];return o}static getExtensionsAt(t,e,n,s){let o=[],a=e;for(;a<s;){let e=n,l=r.getIntAt(t,a,n);if(!l)break;if(l+a>s&&(e=!e,l=r.getIntAt(t,a,e),l+a>s))throw new Error("This does not appear to be a valid NIFTI extension");if(l%16!=0)throw new Error("This does not appear to be a NIFTI extension");let f=r.getIntAt(t,a+4,e),h=t.buffer.slice(a+8,a+l);console.log("extensionByteIndex: "+(a+8)+" esize: "+l),console.log(h);let u=new i.NIFTIEXTENSION(l,f,h,e);o.push(u),a+=l}return o}static toArrayBuffer(t){var e,n,i;for(e=new ArrayBuffer(t.length),n=new Uint8Array(e),i=0;i<t.length;i+=1)n[i]=t[i];return e}static isString(t){return"string"==typeof t||t instanceof String}static formatNumber(t,e=void 0){let n;return n=r.isString(t)?Number(t):t,n=e?n.toPrecision(5):n.toPrecision(7),parseFloat(n)}static makeCRCTable(){let t,e=[];for(var n=0;n<256;n++){t=n;for(var i=0;i<8;i++)t=1&t?3988292384^t>>>1:t>>>1;e[n]=t}return e}static crc32(t){r.crcTable||(r.crcTable=r.makeCRCTable());const e=r.crcTable;let n=-1;for(var i=0;i<t.byteLength;i++)n=n>>>8^e[255&(n^t.getUint8(i))];return(-1^n)>>>0}}e.Utils=r},953:function(e){"use strict";e.exports=t},976:function(t){"use strict";t.exports=e},609:function(t,e,n){var i=n(425).default;function r(){"use strict";t.exports=r=function(){return e},t.exports.__esModule=!0,t.exports.default=t.exports;var e={},n=Object.prototype,s=n.hasOwnProperty,o=Object.defineProperty||function(t,e,n){t[e]=n.value},a="function"==typeof Symbol?Symbol:{},l=a.iterator||"@@iterator",f=a.asyncIterator||"@@asyncIterator",h=a.toStringTag||"@@toStringTag";function u(t,e,n){return 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e=[t[0][3],t[1][3],t[2][3]],n=[Math.sqrt(Math.pow(t[0][0],2)+Math.pow(t[1][0],2)+Math.pow(t[2][0],2)),Math.sqrt(Math.pow(t[0][1],2)+Math.pow(t[1][1],2)+Math.pow(t[2][1],2)),Math.sqrt(Math.pow(t[0][2],2)+Math.pow(t[1][2],2)+Math.pow(t[2][2],2))];return{origin:e,orientation:[t[0][0]/n[0],t[0][1]/n[1],t[0][2]/n[2],t[1][0]/n[0],t[1][1]/n[1],t[1][2]/n[2],t[2][0]/n[0],t[2][1]/n[1],t[2][2]/n[2]],spacing:n}}(t.affine),n=e.orientation,i=e.origin,r=e.spacing;return{origin:[-i[0],-i[1],i[2]],orientation:[-n[0],-n[3],n[6],-n[1],-n[4],n[7],-n[2],-n[5],n[8]],spacing:r}}function E(t,e){var n=t.length,i=e.scl_slope,r=e.scl_inter;if(i&&0!==i&&!Number.isNaN(i))for(var s=0;s<n;s++)t[s]=t[s]*i+r}var b=function(t){return t.NIFTI_VOLUME_LOADED="CORNERSTONE_NIFTI_VOLUME_LOADED",t.NIFTI_VOLUME_PROGRESS="CORNERSTONE_NIFTI_VOLUME_PROGRESS",t}(b||{}),x=b,A="nifti",w=l.utilities.createUint8SharedArray,T=l.utilities.createFloat32SharedArray,N=new Map;function U(t,e,n,i){return new Promise((function(r,s){var o=new 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n=this&&this.__createBinding||(Object.create?function(t,e,i,n){void 0===n&&(n=i);var s=Object.getOwnPropertyDescriptor(e,i);s&&!("get"in s?!e.__esModule:s.writable||s.configurable)||(s={enumerable:!0,get:function(){return e[i]}}),Object.defineProperty(t,n,s)}:function(t,e,i,n){void 0===n&&(n=i),t[n]=e[i]}),s=this&&this.__setModuleDefault||(Object.create?function(t,e){Object.defineProperty(t,"default",{enumerable:!0,value:e})}:function(t,e){t.default=e}),r=this&&this.__importStar||function(t){if(t&&t.__esModule)return t;var e={};if(null!=t)for(var i in t)"default"!==i&&Object.prototype.hasOwnProperty.call(t,i)&&n(e,t,i);return s(e,t),e};Object.defineProperty(e,"__esModule",{value:!0}),e.readExtensionData=e.readExtension=e.readImage=e.hasExtension=e.readHeader=e.decompress=e.isCompressed=e.isNIFTI=e.isNIFTI2=e.isNIFTI1=e.NIFTIEXTENSION=e.Utils=e.NIFTI2=e.NIFTI1=void 0;const o=r(i(471)),a=i(232),l=i(103),h=i(517);var f=i(232);Object.defineProperty(e,"NIFTI1",{enumerable:!0,get:function(){return f.NIFTI1}});var c=i(103);Object.defineProperty(e,"NIFTI2",{enumerable:!0,get:function(){return c.NIFTI2}});var u=i(517);Object.defineProperty(e,"Utils",{enumerable:!0,get:function(){return u.Utils}});var d=i(237);function p(t,e=!1){var i,n,s,r;return!(t.byteLength<a.NIFTI1.STANDARD_HEADER_SIZE||((i=new DataView(t))&&(n=i.getUint8(a.NIFTI1.MAGIC_NUMBER_LOCATION)),s=i.getUint8(a.NIFTI1.MAGIC_NUMBER_LOCATION+1),r=i.getUint8(a.NIFTI1.MAGIC_NUMBER_LOCATION+2),!(e&&n===a.NIFTI1.MAGIC_NUMBER2[0]&&s===a.NIFTI1.MAGIC_NUMBER2[1]&&r===a.NIFTI1.MAGIC_NUMBER2[2]||n===a.NIFTI1.MAGIC_NUMBER[0]&&s===a.NIFTI1.MAGIC_NUMBER[1]&&r===a.NIFTI1.MAGIC_NUMBER[2])))}function g(t,e=!1){var i,n,s,r;return!(t.byteLength<a.NIFTI1.STANDARD_HEADER_SIZE||(n=(i=new DataView(t)).getUint8(l.NIFTI2.MAGIC_NUMBER_LOCATION),s=i.getUint8(l.NIFTI2.MAGIC_NUMBER_LOCATION+1),r=i.getUint8(l.NIFTI2.MAGIC_NUMBER_LOCATION+2),!(e&&n===l.NIFTI2.MAGIC_NUMBER2[0]&&s===l.NIFTI2.MAGIC_NUMBER2[1]&&r===l.NIFTI2.MAGIC_NUMBER2[2]||n===l.NIFTI2.MAGIC_NUMBER[0]&&s===l.NIFTI2.MAGIC_NUMBER[1]&&r===l.NIFTI2.MAGIC_NUMBER[2])))}function m(t){var e,i,n;if(t){if(i=(e=new DataView(t)).getUint8(0),n=e.getUint8(1),i===h.Utils.GUNZIP_MAGIC_COOKIE1)return!0;if(n===h.Utils.GUNZIP_MAGIC_COOKIE2)return!0}return!1}function _(t){return o.decompressSync(new Uint8Array(t)).buffer}Object.defineProperty(e,"NIFTIEXTENSION",{enumerable:!0,get:function(){return d.NIFTIEXTENSION}}),e.isNIFTI1=p,e.isNIFTI2=g,e.isNIFTI=function(t,e=!1){return p(t,e)||g(t,e)},e.isCompressed=m,e.decompress=_,e.readHeader=function(t,e=!1){var i=null;return m(t)&&(t=_(t)),p(t,e)?i=new a.NIFTI1:g(t,e)&&(i=new l.NIFTI2),i?i.readHeader(t):console.error("That file does not appear to be NIFTI!"),i},e.hasExtension=function(t){return 0!=t.extensionFlag[0]},e.readImage=function(t,e){var i=t.vox_offset,n=1,s=1;t.dims[4]&&(n=t.dims[4]),t.dims[5]&&(s=t.dims[5]);var r=t.dims[1]*t.dims[2]*t.dims[3]*n*s*(t.numBitsPerVoxel/8);return e.slice(i,i+r)},e.readExtension=function(t,e){var i=t.getExtensionLocation(),n=t.extensionSize;return e.slice(i,i+n)},e.readExtensionData=function(t,e){var i=t.getExtensionLocation(),n=t.extensionSize;return e.slice(i+8,i+n)}},232:(t,e,i)=>{Object.defineProperty(e,"__esModule",{value:!0}),e.NIFTI1=void 0;const n=i(517);class s{littleEndian=!1;dim_info=0;dims=[];intent_p1=0;intent_p2=0;intent_p3=0;intent_code=0;datatypeCode=0;numBitsPerVoxel=0;slice_start=0;slice_end=0;slice_code=0;pixDims=[];vox_offset=0;scl_slope=1;scl_inter=0;xyzt_units=0;cal_max=0;cal_min=0;slice_duration=0;toffset=0;description="";aux_file="";intent_name="";qform_code=0;sform_code=0;quatern_a=0;quatern_b=0;quatern_c=0;quatern_d=0;qoffset_x=0;qoffset_y=0;qoffset_z=0;affine=[[1,0,0,0],[0,1,0,0],[0,0,1,0],[0,0,0,1]];qfac=1;quatern_R;magic="0";isHDR=!1;extensionFlag=[0,0,0,0];extensionSize=0;extensionCode=0;extensions=[];static TYPE_NONE=0;static TYPE_BINARY=1;static TYPE_UINT8=2;static TYPE_INT16=4;static TYPE_INT32=8;static TYPE_FLOAT32=16;static TYPE_COMPLEX64=32;static TYPE_FLOAT64=64;static TYPE_RGB24=128;static TYPE_INT8=256;static TYPE_UINT16=512;static TYPE_UINT32=768;static TYPE_INT64=1024;static TYPE_UINT64=1280;static TYPE_FLOAT128=1536;static TYPE_COMPLEX128=1792;static TYPE_COMPLEX256=2048;static XFORM_UNKNOWN=0;static XFORM_SCANNER_ANAT=1;static XFORM_ALIGNED_ANAT=2;static XFORM_TALAIRACH=3;static XFORM_MNI_152=4;static SPATIAL_UNITS_MASK=7;static TEMPORAL_UNITS_MASK=56;static UNITS_UNKNOWN=0;static UNITS_METER=1;static UNITS_MM=2;static UNITS_MICRON=3;static UNITS_SEC=8;static UNITS_MSEC=16;static UNITS_USEC=24;static UNITS_HZ=32;static UNITS_PPM=40;static UNITS_RADS=48;static MAGIC_COOKIE=348;static STANDARD_HEADER_SIZE=348;static MAGIC_NUMBER_LOCATION=344;static MAGIC_NUMBER=[110,43,49];static MAGIC_NUMBER2=[110,105,49];static EXTENSION_HEADER_SIZE=8;readHeader(t){var e,i,r,o,a=new DataView(t),l=n.Utils.getIntAt(a,0,this.littleEndian);if(l!==s.MAGIC_COOKIE&&(this.littleEndian=!0,l=n.Utils.getIntAt(a,0,this.littleEndian)),l!==s.MAGIC_COOKIE)throw new Error("This does not appear to be a NIFTI file!");for(this.dim_info=n.Utils.getByteAt(a,39),e=0;e<8;e+=1)o=40+2*e,this.dims[e]=n.Utils.getShortAt(a,o,this.littleEndian);for(this.intent_p1=n.Utils.getFloatAt(a,56,this.littleEndian),this.intent_p2=n.Utils.getFloatAt(a,60,this.littleEndian),this.intent_p3=n.Utils.getFloatAt(a,64,this.littleEndian),this.intent_code=n.Utils.getShortAt(a,68,this.littleEndian),this.datatypeCode=n.Utils.getShortAt(a,70,this.littleEndian),this.numBitsPerVoxel=n.Utils.getShortAt(a,72,this.littleEndian),this.slice_start=n.Utils.getShortAt(a,74,this.littleEndian),e=0;e<8;e+=1)o=76+4*e,this.pixDims[e]=n.Utils.getFloatAt(a,o,this.littleEndian);if(this.vox_offset=n.Utils.getFloatAt(a,108,this.littleEndian),this.scl_slope=n.Utils.getFloatAt(a,112,this.littleEndian),this.scl_inter=n.Utils.getFloatAt(a,116,this.littleEndian),this.slice_end=n.Utils.getShortAt(a,120,this.littleEndian),this.slice_code=n.Utils.getByteAt(a,122),this.xyzt_units=n.Utils.getByteAt(a,123),this.cal_max=n.Utils.getFloatAt(a,124,this.littleEndian),this.cal_min=n.Utils.getFloatAt(a,128,this.littleEndian),this.slice_duration=n.Utils.getFloatAt(a,132,this.littleEndian),this.toffset=n.Utils.getFloatAt(a,136,this.littleEndian),this.description=n.Utils.getStringAt(a,148,228),this.aux_file=n.Utils.getStringAt(a,228,252),this.qform_code=n.Utils.getShortAt(a,252,this.littleEndian),this.sform_code=n.Utils.getShortAt(a,254,this.littleEndian),this.quatern_b=n.Utils.getFloatAt(a,256,this.littleEndian),this.quatern_c=n.Utils.getFloatAt(a,260,this.littleEndian),this.quatern_d=n.Utils.getFloatAt(a,264,this.littleEndian),this.quatern_a=Math.sqrt(1-(Math.pow(this.quatern_b,2)+Math.pow(this.quatern_c,2)+Math.pow(this.quatern_d,2))),this.qoffset_x=n.Utils.getFloatAt(a,268,this.littleEndian),this.qoffset_y=n.Utils.getFloatAt(a,272,this.littleEndian),this.qoffset_z=n.Utils.getFloatAt(a,276,this.littleEndian),this.qform_code<1&&this.sform_code<1&&(this.affine[0][0]=this.pixDims[1],this.affine[1][1]=this.pixDims[2],this.affine[2][2]=this.pixDims[3]),this.qform_code>0&&this.sform_code<this.qform_code){const t=this.quatern_a,e=this.quatern_b,n=this.quatern_c,s=this.quatern_d;for(this.qfac=0===this.pixDims[0]?1:this.pixDims[0],this.quatern_R=[[t*t+e*e-n*n-s*s,2*e*n-2*t*s,2*e*s+2*t*n],[2*e*n+2*t*s,t*t+n*n-e*e-s*s,2*n*s-2*t*e],[2*e*s-2*t*n,2*n*s+2*t*e,t*t+s*s-n*n-e*e]],i=0;i<3;i+=1)for(r=0;r<3;r+=1)this.affine[i][r]=this.quatern_R[i][r]*this.pixDims[r+1],2===r&&(this.affine[i][r]*=this.qfac);this.affine[0][3]=this.qoffset_x,this.affine[1][3]=this.qoffset_y,this.affine[2][3]=this.qoffset_z}else if(this.sform_code>0)for(i=0;i<3;i+=1)for(r=0;r<4;r+=1)o=280+4*(4*i+r),this.affine[i][r]=n.Utils.getFloatAt(a,o,this.littleEndian);this.affine[3][0]=0,this.affine[3][1]=0,this.affine[3][2]=0,this.affine[3][3]=1,this.intent_name=n.Utils.getStringAt(a,328,344),this.magic=n.Utils.getStringAt(a,344,348),this.isHDR=this.magic===String.fromCharCode.apply(null,s.MAGIC_NUMBER2),a.byteLength>s.MAGIC_COOKIE&&(this.extensionFlag[0]=n.Utils.getByteAt(a,348),this.extensionFlag[1]=n.Utils.getByteAt(a,349),this.extensionFlag[2]=n.Utils.getByteAt(a,350),this.extensionFlag[3]=n.Utils.getByteAt(a,351),this.extensionFlag[0]&&(this.extensions=n.Utils.getExtensionsAt(a,this.getExtensionLocation(),this.littleEndian,this.vox_offset),this.extensionSize=this.extensions[0].esize,this.extensionCode=this.extensions[0].ecode))}toFormattedString(){var t=n.Utils.formatNumber,e="";return e+="Dim Info = "+this.dim_info+"\n",e+="Image Dimensions (1-8): "+this.dims[0]+", "+this.dims[1]+", "+this.dims[2]+", "+this.dims[3]+", "+this.dims[4]+", "+this.dims[5]+", "+this.dims[6]+", "+this.dims[7]+"\n",e+="Intent Parameters (1-3): "+this.intent_p1+", "+this.intent_p2+", "+this.intent_p3+"\n",e+="Intent Code = "+this.intent_code+"\n",e+="Datatype = "+this.datatypeCode+" ("+this.getDatatypeCodeString(this.datatypeCode)+")\n",e+="Bits Per Voxel = "+this.numBitsPerVoxel+"\n",e+="Slice Start = "+this.slice_start+"\n",e+="Voxel Dimensions (1-8): "+t(this.pixDims[0])+", "+t(this.pixDims[1])+", "+t(this.pixDims[2])+", "+t(this.pixDims[3])+", "+t(this.pixDims[4])+", "+t(this.pixDims[5])+", "+t(this.pixDims[6])+", "+t(this.pixDims[7])+"\n",e+="Image Offset = "+this.vox_offset+"\n",e+="Data Scale:  Slope = "+t(this.scl_slope)+"  Intercept = "+t(this.scl_inter)+"\n",e+="Slice End = "+this.slice_end+"\n",e+="Slice Code = "+this.slice_code+"\n",e+="Units Code = "+this.xyzt_units+" ("+this.getUnitsCodeString(s.SPATIAL_UNITS_MASK&this.xyzt_units)+", "+this.getUnitsCodeString(s.TEMPORAL_UNITS_MASK&this.xyzt_units)+")\n",e+="Display Range:  Max = "+t(this.cal_max)+"  Min = "+t(this.cal_min)+"\n",e+="Slice Duration = "+this.slice_duration+"\n",e+="Time Axis Shift = "+this.toffset+"\n",e+='Description: "'+this.description+'"\n',e+='Auxiliary File: "'+this.aux_file+'"\n',e+="Q-Form Code = "+this.qform_code+" ("+this.getTransformCodeString(this.qform_code)+")\n",e+="S-Form Code = "+this.sform_code+" ("+this.getTransformCodeString(this.sform_code)+")\n",e+="Quaternion Parameters:  b = "+t(this.quatern_b)+"  c = "+t(this.quatern_c)+"  d = "+t(this.quatern_d)+"\n",e+="Quaternion Offsets:  x = "+this.qoffset_x+"  y = "+this.qoffset_y+"  z = "+this.qoffset_z+"\n",e+="S-Form Parameters X: "+t(this.affine[0][0])+", "+t(this.affine[0][1])+", "+t(this.affine[0][2])+", "+t(this.affine[0][3])+"\n",e+="S-Form Parameters Y: "+t(this.affine[1][0])+", "+t(this.affine[1][1])+", "+t(this.affine[1][2])+", "+t(this.affine[1][3])+"\n",e+="S-Form Parameters Z: "+t(this.affine[2][0])+", "+t(this.affine[2][1])+", "+t(this.affine[2][2])+", "+t(this.affine[2][3])+"\n",e+='Intent Name: "'+this.intent_name+'"\n',this.extensionFlag[0]&&(e+="Extension: Size = "+this.extensionSize+"  Code = "+this.extensionCode+"\n"),e}getDatatypeCodeString=function(t){return t===s.TYPE_UINT8?"1-Byte Unsigned Integer":t===s.TYPE_INT16?"2-Byte Signed Integer":t===s.TYPE_INT32?"4-Byte Signed Integer":t===s.TYPE_FLOAT32?"4-Byte Float":t===s.TYPE_FLOAT64?"8-Byte Float":t===s.TYPE_RGB24?"RGB":t===s.TYPE_INT8?"1-Byte Signed Integer":t===s.TYPE_UINT16?"2-Byte Unsigned Integer":t===s.TYPE_UINT32?"4-Byte Unsigned Integer":t===s.TYPE_INT64?"8-Byte Signed Integer":t===s.TYPE_UINT64?"8-Byte Unsigned Integer":"Unknown"};getTransformCodeString=function(t){return t===s.XFORM_SCANNER_ANAT?"Scanner":t===s.XFORM_ALIGNED_ANAT?"Aligned":t===s.XFORM_TALAIRACH?"Talairach":t===s.XFORM_MNI_152?"MNI":"Unknown"};getUnitsCodeString=function(t){return t===s.UNITS_METER?"Meters":t===s.UNITS_MM?"Millimeters":t===s.UNITS_MICRON?"Microns":t===s.UNITS_SEC?"Seconds":t===s.UNITS_MSEC?"Milliseconds":t===s.UNITS_USEC?"Microseconds":t===s.UNITS_HZ?"Hz":t===s.UNITS_PPM?"PPM":t===s.UNITS_RADS?"Rads":"Unknown"};getQformMat(){return this.convertNiftiQFormToNiftiSForm(this.quatern_b,this.quatern_c,this.quatern_d,this.qoffset_x,this.qoffset_y,this.qoffset_z,this.pixDims[1],this.pixDims[2],this.pixDims[3],this.pixDims[0])}convertNiftiQFormToNiftiSForm(t,e,i,n,s,r,o,a,l,h){var f,c,u,d,p=[[0,0,0,0],[0,0,0,0],[0,0,0,0],[0,0,0,0]],g=t,m=e,_=i;return p[3][0]=p[3][1]=p[3][2]=0,p[3][3]=1,(f=1-(g*g+m*m+_*_))<1e-7?(g*=f=1/Math.sqrt(g*g+m*m+_*_),m*=f,_*=f,f=0):f=Math.sqrt(f),c=o>0?o:1,u=a>0?a:1,d=l>0?l:1,h<0&&(d=-d),p[0][0]=(f*f+g*g-m*m-_*_)*c,p[0][1]=2*(g*m-f*_)*u,p[0][2]=2*(g*_+f*m)*d,p[1][0]=2*(g*m+f*_)*c,p[1][1]=(f*f+m*m-g*g-_*_)*u,p[1][2]=2*(m*_-f*g)*d,p[2][0]=2*(g*_-f*m)*c,p[2][1]=2*(m*_+f*g)*u,p[2][2]=(f*f+_*_-m*m-g*g)*d,p[0][3]=n,p[1][3]=s,p[2][3]=r,p}convertNiftiSFormToNEMA(t){var e,i,n,s,r,o,a,l,h,f,c,u,d,p,g,m,_,v,I,E,y,A,b,T,x,U,N,S,F,M,w,C,O;if(p=0,U=[[0,0,0],[0,0,0],[0,0,0]],N=[[0,0,0],[0,0,0],[0,0,0]],e=t[0][0],i=t[0][1],n=t[0][2],s=t[1][0],r=t[1][1],o=t[1][2],a=t[2][0],l=t[2][1],h=t[2][2],0===(f=Math.sqrt(e*e+s*s+a*a)))return null;if(e/=f,s/=f,a/=f,0===(f=Math.sqrt(i*i+r*r+l*l)))return null;if(f=e*(i/=f)+s*(r/=f)+a*(l/=f),Math.abs(f)>1e-4){if(i-=f*e,r-=f*s,l-=f*a,0===(f=Math.sqrt(i*i+r*r+l*l)))return null;i/=f,r/=f,l/=f}if(0===(f=Math.sqrt(n*n+o*o+h*h))?(n=s*l-a*r,o=a*i-l*e,h=e*r-s*i):(n/=f,o/=f,h/=f),f=e*n+s*o+a*h,Math.abs(f)>1e-4){if(n-=f*e,o-=f*s,h-=f*a,0===(f=Math.sqrt(n*n+o*o+h*h)))return null;n/=f,o/=f,h/=f}if(f=i*n+r*o+l*h,Math.abs(f)>1e-4){if(n-=f*i,o-=f*r,h-=f*l,0===(f=Math.sqrt(n*n+o*o+h*h)))return null;n/=f,o/=f,h/=f}if(U[0][0]=e,U[0][1]=i,U[0][2]=n,U[1][0]=s,U[1][1]=r,U[1][2]=o,U[2][0]=a,U[2][1]=l,U[2][2]=h,0===(c=this.nifti_mat33_determ(U)))return null;for(x=-666,v=y=A=b=1,I=2,E=3,u=1;u<=3;u+=1)for(d=1;d<=3;d+=1)if(u!==d)for(p=1;p<=3;p+=1)if(u!==p&&d!==p)for(N[0][0]=N[0][1]=N[0][2]=N[1][0]=N[1][1]=N[1][2]=N[2][0]=N[2][1]=N[2][2]=0,g=-1;g<=1;g+=2)for(m=-1;m<=1;m+=2)for(_=-1;_<=1;_+=2)N[0][u-1]=g,N[1][d-1]=m,N[2][p-1]=_,this.nifti_mat33_determ(N)*c>0&&(f=(T=this.nifti_mat33_mul(N,U))[0][0]+T[1][1]+T[2][2])>x&&(x=f,v=u,I=d,E=p,y=g,A=m,b=_);switch(S=F=M=w=C=O="",v*y){case 1:S="X",w="+";break;case-1:S="X",w="-";break;case 2:S="Y",w="+";break;case-2:S="Y",w="-";break;case 3:S="Z",w="+";break;case-3:S="Z",w="-"}switch(I*A){case 1:F="X",C="+";break;case-1:F="X",C="-";break;case 2:F="Y",C="+";break;case-2:F="Y",C="-";break;case 3:F="Z",C="+";break;case-3:F="Z",C="-"}switch(E*b){case 1:M="X",O="+";break;case-1:M="X",O="-";break;case 2:M="Y",O="+";break;case-2:M="Y",O="-";break;case 3:M="Z",O="+";break;case-3:M="Z",O="-"}return S+F+M+w+C+O}nifti_mat33_mul=function(t,e){var i,n,s=[[0,0,0],[0,0,0],[0,0,0]];for(i=0;i<3;i+=1)for(n=0;n<3;n+=1)s[i][n]=t[i][0]*e[0][n]+t[i][1]*e[1][n]+t[i][2]*e[2][n];return s};nifti_mat33_determ=function(t){var e,i,n,s,r,o,a,l,h;return e=t[0][0],i=t[0][1],n=t[0][2],s=t[1][0],r=t[1][1],o=t[1][2],a=t[2][0],l=t[2][1],e*r*(h=t[2][2])-e*l*o-s*i*h+s*l*n+a*i*o-a*r*n};getExtensionLocation(){return s.MAGIC_COOKIE+4}getExtensionSize(t){return n.Utils.getIntAt(t,this.getExtensionLocation(),this.littleEndian)}getExtensionCode(t){return n.Utils.getIntAt(t,this.getExtensionLocation()+4,this.littleEndian)}addExtension(t,e=-1){-1==e?this.extensions.push(t):this.extensions.splice(e,0,t),this.vox_offset+=t.esize}removeExtension(t){let e=this.extensions[t];e&&(this.vox_offset-=e.esize),this.extensions.splice(t,1)}toArrayBuffer(t=!1){let e=352;if(t)for(let t of this.extensions)e+=t.esize;let i=new Uint8Array(e),n=new DataView(i.buffer);n.setInt32(0,348,this.littleEndian),n.setUint8(39,this.dim_info);for(let t=0;t<8;t++)n.setUint16(40+2*t,this.dims[t],this.littleEndian);n.setFloat32(56,this.intent_p1,this.littleEndian),n.setFloat32(60,this.intent_p2,this.littleEndian),n.setFloat32(64,this.intent_p3,this.littleEndian),n.setInt16(68,this.intent_code,this.littleEndian),n.setInt16(70,this.datatypeCode,this.littleEndian),n.setInt16(72,this.numBitsPerVoxel,this.littleEndian),n.setInt16(74,this.slice_start,this.littleEndian);for(let t=0;t<8;t++)n.setFloat32(76+4*t,this.pixDims[t],this.littleEndian);n.setFloat32(108,this.vox_offset,this.littleEndian),n.setFloat32(112,this.scl_slope,this.littleEndian),n.setFloat32(116,this.scl_inter,this.littleEndian),n.setInt16(120,this.slice_end,this.littleEndian),n.setUint8(122,this.slice_code),n.setUint8(123,this.xyzt_units),n.setFloat32(124,this.cal_max,this.littleEndian),n.setFloat32(128,this.cal_min,this.littleEndian),n.setFloat32(132,this.slice_duration,this.littleEndian),n.setFloat32(136,this.toffset,this.littleEndian),i.set(Buffer.from(this.description),148),i.set(Buffer.from(this.aux_file),228),n.setInt16(252,this.qform_code,this.littleEndian),n.setInt16(254,this.sform_code,this.littleEndian),n.setFloat32(256,this.quatern_b,this.littleEndian),n.setFloat32(260,this.quatern_c,this.littleEndian),n.setFloat32(264,this.quatern_d,this.littleEndian),n.setFloat32(268,this.qoffset_x,this.littleEndian),n.setFloat32(272,this.qoffset_y,this.littleEndian),n.setFloat32(276,this.qoffset_z,this.littleEndian);const s=this.affine.flat();for(let t=0;t<12;t++)n.setFloat32(280+4*t,s[t],this.littleEndian);if(i.set(Buffer.from(this.intent_name),328),i.set(Buffer.from(this.magic),344),t){i.set(Uint8Array.from([1,0,0,0]),348);let t=this.getExtensionLocation();for(const e of this.extensions)n.setInt32(t,e.esize,e.littleEndian),n.setInt32(t+4,e.ecode,e.littleEndian),i.set(new Uint8Array(e.edata),t+8),t+=e.esize}else i.set(new Uint8Array(4).fill(0),348);return i.buffer}}e.NIFTI1=s},103:(t,e,i)=>{Object.defineProperty(e,"__esModule",{value:!0}),e.NIFTI2=void 0;const n=i(232),s=i(517);class r{littleEndian=!1;dim_info=0;dims=[];intent_p1=0;intent_p2=0;intent_p3=0;intent_code=0;datatypeCode=0;numBitsPerVoxel=0;slice_start=0;slice_end=0;slice_code=0;pixDims=[];vox_offset=0;scl_slope=1;scl_inter=0;xyzt_units=0;cal_max=0;cal_min=0;slice_duration=0;toffset=0;description="";aux_file="";intent_name="";qform_code=0;sform_code=0;quatern_b=0;quatern_c=0;quatern_d=0;qoffset_x=0;qoffset_y=0;qoffset_z=0;affine=[[1,0,0,0],[0,1,0,0],[0,0,1,0],[0,0,0,1]];magic="0";extensionFlag=[0,0,0,0];extensions=[];extensionSize=0;extensionCode=0;static MAGIC_COOKIE=540;static MAGIC_NUMBER_LOCATION=4;static MAGIC_NUMBER=[110,43,50,0,13,10,26,10];static MAGIC_NUMBER2=[110,105,50,0,13,10,26,10];readHeader(t){var e,i,n,o,a=new DataView(t),l=s.Utils.getIntAt(a,0,this.littleEndian);if(l!==r.MAGIC_COOKIE&&(this.littleEndian=!0,l=s.Utils.getIntAt(a,0,this.littleEndian)),l!==r.MAGIC_COOKIE)throw new Error("This does not appear to be a NIFTI file!");for(this.magic=s.Utils.getStringAt(a,4,12),this.datatypeCode=s.Utils.getShortAt(a,12,this.littleEndian),this.numBitsPerVoxel=s.Utils.getShortAt(a,14,this.littleEndian),e=0;e<8;e+=1)o=16+8*e,this.dims[e]=s.Utils.getLongAt(a,o,this.littleEndian);for(this.intent_p1=s.Utils.getDoubleAt(a,80,this.littleEndian),this.intent_p2=s.Utils.getDoubleAt(a,88,this.littleEndian),this.intent_p3=s.Utils.getDoubleAt(a,96,this.littleEndian),e=0;e<8;e+=1)o=104+8*e,this.pixDims[e]=s.Utils.getDoubleAt(a,o,this.littleEndian);for(this.vox_offset=s.Utils.getLongAt(a,168,this.littleEndian),this.scl_slope=s.Utils.getDoubleAt(a,176,this.littleEndian),this.scl_inter=s.Utils.getDoubleAt(a,184,this.littleEndian),this.cal_max=s.Utils.getDoubleAt(a,192,this.littleEndian),this.cal_min=s.Utils.getDoubleAt(a,200,this.littleEndian),this.slice_duration=s.Utils.getDoubleAt(a,208,this.littleEndian),this.toffset=s.Utils.getDoubleAt(a,216,this.littleEndian),this.slice_start=s.Utils.getLongAt(a,224,this.littleEndian),this.slice_end=s.Utils.getLongAt(a,232,this.littleEndian),this.description=s.Utils.getStringAt(a,240,320),this.aux_file=s.Utils.getStringAt(a,320,344),this.qform_code=s.Utils.getIntAt(a,344,this.littleEndian),this.sform_code=s.Utils.getIntAt(a,348,this.littleEndian),this.quatern_b=s.Utils.getDoubleAt(a,352,this.littleEndian),this.quatern_c=s.Utils.getDoubleAt(a,360,this.littleEndian),this.quatern_d=s.Utils.getDoubleAt(a,368,this.littleEndian),this.qoffset_x=s.Utils.getDoubleAt(a,376,this.littleEndian),this.qoffset_y=s.Utils.getDoubleAt(a,384,this.littleEndian),this.qoffset_z=s.Utils.getDoubleAt(a,392,this.littleEndian),i=0;i<3;i+=1)for(n=0;n<4;n+=1)o=400+8*(4*i+n),this.affine[i][n]=s.Utils.getDoubleAt(a,o,this.littleEndian);this.affine[3][0]=0,this.affine[3][1]=0,this.affine[3][2]=0,this.affine[3][3]=1,this.slice_code=s.Utils.getIntAt(a,496,this.littleEndian),this.xyzt_units=s.Utils.getIntAt(a,500,this.littleEndian),this.intent_code=s.Utils.getIntAt(a,504,this.littleEndian),this.intent_name=s.Utils.getStringAt(a,508,524),this.dim_info=s.Utils.getByteAt(a,524),a.byteLength>r.MAGIC_COOKIE&&(this.extensionFlag[0]=s.Utils.getByteAt(a,540),this.extensionFlag[1]=s.Utils.getByteAt(a,541),this.extensionFlag[2]=s.Utils.getByteAt(a,542),this.extensionFlag[3]=s.Utils.getByteAt(a,543),this.extensionFlag[0]&&(this.extensions=s.Utils.getExtensionsAt(a,this.getExtensionLocation(),this.littleEndian,this.vox_offset),this.extensionSize=this.extensions[0].esize,this.extensionCode=this.extensions[0].ecode))}toFormattedString(){var t=s.Utils.formatNumber,e="";return e+="Datatype = "+ +this.datatypeCode+" ("+this.getDatatypeCodeString(this.datatypeCode)+")\n",e+="Bits Per Voxel =  = "+this.numBitsPerVoxel+"\n",e+="Image Dimensions (1-8): "+this.dims[0]+", "+this.dims[1]+", "+this.dims[2]+", "+this.dims[3]+", "+this.dims[4]+", "+this.dims[5]+", "+this.dims[6]+", "+this.dims[7]+"\n",e+="Intent Parameters (1-3): "+this.intent_p1+", "+this.intent_p2+", "+this.intent_p3+"\n",e+="Voxel Dimensions (1-8): "+t(this.pixDims[0])+", "+t(this.pixDims[1])+", "+t(this.pixDims[2])+", "+t(this.pixDims[3])+", "+t(this.pixDims[4])+", "+t(this.pixDims[5])+", "+t(this.pixDims[6])+", "+t(this.pixDims[7])+"\n",e+="Image Offset = "+this.vox_offset+"\n",e+="Data Scale:  Slope = "+t(this.scl_slope)+"  Intercept = "+t(this.scl_inter)+"\n",e+="Display Range:  Max = "+t(this.cal_max)+"  Min = "+t(this.cal_min)+"\n",e+="Slice Duration = "+this.slice_duration+"\n",e+="Time Axis Shift = "+this.toffset+"\n",e+="Slice Start = "+this.slice_start+"\n",e+="Slice End = "+this.slice_end+"\n",e+='Description: "'+this.description+'"\n',e+='Auxiliary File: "'+this.aux_file+'"\n',e+="Q-Form Code = "+this.qform_code+" ("+this.getTransformCodeString(this.qform_code)+")\n",e+="S-Form Code = "+this.sform_code+" ("+this.getTransformCodeString(this.sform_code)+")\n",e+="Quaternion Parameters:  b = "+t(this.quatern_b)+"  c = "+t(this.quatern_c)+"  d = "+t(this.quatern_d)+"\n",e+="Quaternion Offsets:  x = "+this.qoffset_x+"  y = "+this.qoffset_y+"  z = "+this.qoffset_z+"\n",e+="S-Form Parameters X: "+t(this.affine[0][0])+", "+t(this.affine[0][1])+", "+t(this.affine[0][2])+", "+t(this.affine[0][3])+"\n",e+="S-Form Parameters Y: "+t(this.affine[1][0])+", "+t(this.affine[1][1])+", "+t(this.affine[1][2])+", "+t(this.affine[1][3])+"\n",e+="S-Form Parameters Z: "+t(this.affine[2][0])+", "+t(this.affine[2][1])+", "+t(this.affine[2][2])+", "+t(this.affine[2][3])+"\n",e+="Slice Code = "+this.slice_code+"\n",e+="Units Code = "+this.xyzt_units+" ("+this.getUnitsCodeString(n.NIFTI1.SPATIAL_UNITS_MASK&this.xyzt_units)+", "+this.getUnitsCodeString(n.NIFTI1.TEMPORAL_UNITS_MASK&this.xyzt_units)+")\n",e+="Intent Code = "+this.intent_code+"\n",(e+='Intent Name: "'+this.intent_name+'"\n')+"Dim Info = "+this.dim_info+"\n"}getExtensionLocation=function(){return 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e=function(t,e){if("object"!==l(t)||null===t)return t;var i=t[Symbol.toPrimitive];if(void 0!==i){var n=i.call(t,"string");if("object"!==l(n))return n;throw new TypeError("@@toPrimitive must return a primitive value.")}return String(t)}(t);return"symbol"===l(e)?e:String(e)}(e))in t?Object.defineProperty(t,e,{value:i,enumerable:!0,configurable:!0,writable:!0}):t[e]=i,t}class f extends n.ImageVolume{constructor(t,e){super(t),h(this,"loadStatus",void 0),h(this,"controller",void 0),h(this,"cancelLoading",(()=>{const{loadStatus:t}=this;t&&t.loading&&(t.loading=!1,this.clearLoadCallbacks(),this.controller.abort())})),h(this,"load",(function(t){})),this.loadStatus=e.loadStatus,this.controller=e.controller}clearLoadCallbacks(){this.loadStatus.callbacks=[]}decache(){n.cache.removeVolumeLoadObject(this.volumeId)}}const c=(t,e)=>{let i,n;if(e instanceof Uint8Array||e instanceof ArrayBuffer||e instanceof SharedArrayBuffer)i=Uint8Array,n=1;else if(e instanceof Int16Array)i=Int16Array,n=2;else{if(!(e instanceof Float32Array))throw new Error("imageDataArray needs to be a Uint8Array, Int16Array or Float32Array.");i=Float32Array,n=4}const s=new i(e.byteLength),r=new i(e);s.set(r);const o=t[2],a=t[0]*t[1],l=s.buffer;for(let t=0;t<o;t++)new i(l,a*t*n,a).reverse();return s};function u(t,e){const i=t.length,{scl_slope:n,scl_inter:s}=e;if(n&&0!==n&&!Number.isNaN(n))for(let e=0;e<i;e++)t[e]=t[e]*n+s}var d=function(t){return t.NIFTI_VOLUME_LOADED="CORNERSTONE_NIFTI_VOLUME_LOADED",t.NIFTI_VOLUME_PROGRESS="CORNERSTONE_NIFTI_VOLUME_PROGRESS",t}(d||{});const p=d,g="nifti",{createUint8SharedArray:m,createFloat32SharedArray:_}=n.utilities,v=new Map,I=(t,e)=>{switch(t){case 2:return new Uint8Array(e);case 16:return new Float32Array(e);case 4:return new Int16Array(e);default:throw new Error("datatypeCode ".concat(t," is not yet supported"))}};async function E(t){const e=t.substring(g.length+1),s=new AbortController,r=s.signal;v.set(e,{controller:s,loading:!0});let l=await function(t,e,i,n){return new Promise(((s,r)=>{const o=new XMLHttpRequest;o.open("GET",t,!0),o.responseType="arraybuffer";const a=function(t){n&&n(),i&&i.removeEventListener("abort",l),s(o.response)},l=()=>{o.abort(),o.removeEventListener("load",a),r(new Error("Request aborted"))};o.addEventListener("load",a),e&&(o.onprogress=function(t){e(t.loaded,t.total)}),i&&i.aborted?(o.abort(),r(new Error("Request aborted"))):i&&i.addEventListener("abort",l),o.send()}))}(e,((e,i)=>{const s={volumeId:t,loaded:e,total:i};(0,n.triggerEvent)(n.eventTarget,p.NIFTI_VOLUME_PROGRESS,{data:s})}),r,(()=>{const e={volumeId:t};(0,n.triggerEvent)(n.eventTarget,p.NIFTI_VOLUME_LOADED,{data:e})}));v.delete(e);let h=null,d=null;i.isCompressed(l)&&(l=i.decompress(l)),i.isNIFTI(l)&&(h=i.readHeader(l),d=i.readImage(h,l));const E=I(h.datatypeCode,d),{orientation:y,origin:A,spacing:b}=function(t){const{affine:e}=t,{orientation:i,origin:n,spacing:s}=function(t){const e=[t[0][3],t[1][3],t[2][3]],i=[Math.sqrt(t[0][0]**2+t[1][0]**2+t[2][0]**2),Math.sqrt(t[0][1]**2+t[1][1]**2+t[2][1]**2),Math.sqrt(t[0][2]**2+t[1][2]**2+t[2][2]**2)];return{origin:e,orientation:[t[0][0]/i[0],t[0][1]/i[1],t[0][2]/i[2],t[1][0]/i[0],t[1][1]/i[1],t[1][2]/i[2],t[2][0]/i[0],t[2][1]/i[1],t[2][2]/i[2]],spacing:i}}(e);return{origin:[-n[0],-n[1],n[2]],orientation:[-i[0],-i[3],i[6],-i[1],-i[4],i[7],-i[2],-i[5],i[8]],spacing:s}}(h);c(h.dims.slice(1,4),E),u(E,h);const T=a(h,y,E),x=o.vec3.create();o.vec3.set(x,y[6],y[7],y[8]);const{BitsAllocated:U,PixelRepresentation:N,PhotometricInterpretation:S,ImageOrientationPatient:F,Columns:M,Rows:w}=T,C=o.vec3.fromValues(F[0],F[1],F[2]),O=o.vec3.fromValues(F[3],F[4],F[5]),{dims:D}=h,z=[M,w,D[3]],P=new Float32Array([C[0],C[1],C[2],O[0],O[1],O[2],x[0],x[1],x[2]]),q=1===N;let B=1;16!==U&&32!==U||(B=4);let R=1;"RGB"===S&&(R=3);const L=B*z[0]*z[1]*z[2]*R;if(!n.cache.isCacheable(L))throw new Error(n.Enums.Events.CACHE_SIZE_EXCEEDED);let k;switch(n.cache.decacheIfNecessaryUntilBytesAvailable(L),U){case 8:if(q)throw new Error("8 Bit signed images are not yet supported by this plugin.");k=m(z[0]*z[1]*z[2]);break;case 16:case 32:k=_(z[0]*z[1]*z[2])}return k.set(E),new f({volumeId:t,metadata:T,dimensions:z,spacing:b,origin:A,direction:P,scalarData:k,sizeInBytes:L},{loadStatus:{loaded:!1,loading:!1,callbacks:[]},controller:s})}function y(t){return{promise:E(t),cancel:()=>{}}}})(),r})()));
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