@amboss/design-system 4.0.0-next.3 → 4.0.0-next.6

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (280) hide show
  1. package/build/cjs/components/AIButton/AIButton.js +1 -4
  2. package/build/cjs/components/AIFloatingButton/AIFloatingButton.d.ts +10 -0
  3. package/build/cjs/components/AIFloatingButton/AIFloatingButton.js +1 -0
  4. package/build/cjs/components/AvatarGroup/AvatarGroup.d.ts +3 -3
  5. package/build/cjs/components/AvatarGroup/AvatarGroup.js +1 -1
  6. package/build/cjs/components/BinaryFeedback/-types.d.ts +1 -1
  7. package/build/cjs/components/BulkActionsToolbar/BulkActionsToolbar.d.ts +1 -1
  8. package/build/cjs/components/CatalogCard/CatalogCard.js +1 -1
  9. package/build/cjs/components/ChatMessage/ChatMessage.d.ts +46 -0
  10. package/build/cjs/components/ChatMessage/ChatMessage.js +1 -0
  11. package/build/cjs/components/ChatMessage/index.d.ts +2 -0
  12. package/build/cjs/components/ChatMessage/index.js +1 -0
  13. package/build/cjs/components/ChatResponse/ChatResponse.d.ts +50 -0
  14. package/build/cjs/components/ChatResponse/ChatResponse.js +1 -0
  15. package/build/cjs/components/ChatResponse/constants.d.ts +7 -0
  16. package/build/cjs/components/ChatResponse/constants.js +1 -0
  17. package/build/cjs/components/ChatResponse/index.d.ts +2 -0
  18. package/build/cjs/components/ChatResponse/index.js +1 -0
  19. package/build/cjs/components/ColorPicker/ColorPicker.d.ts +1 -1
  20. package/build/cjs/components/ColorPicker/ColorPickerDropdown.d.ts +1 -1
  21. package/build/cjs/components/Content/ContentPictogramButton/ContentPictogramButton.d.ts +1 -1
  22. package/build/cjs/components/Content/ContentTableModal/ContentTableModal.d.ts +1 -1
  23. package/build/cjs/components/EntityList/BaseEntityList.js +1 -1
  24. package/build/cjs/components/EntityList/VirtualizedEntityList.d.ts +3 -2
  25. package/build/cjs/components/EntityList/roles.d.ts +9 -0
  26. package/build/cjs/components/EntityList/roles.js +1 -0
  27. package/build/cjs/components/EntityList/types.d.ts +24 -7
  28. package/build/cjs/components/Form/SegmentedControl/-types.d.ts +3 -3
  29. package/build/cjs/components/Form/ToolbarToggle/-types.d.ts +1 -1
  30. package/build/cjs/components/Icon/Icon.d.ts +2 -2
  31. package/build/cjs/components/Icon/Icon.js +1 -1
  32. package/build/cjs/components/IconTile/IconTile.d.ts +1 -1
  33. package/build/cjs/components/Image/Image.d.ts +13 -21
  34. package/build/cjs/components/Image/Image.js +1 -1
  35. package/build/cjs/components/Internal/BaseTag/BaseTag.d.ts +1 -1
  36. package/build/cjs/components/Internal/Float/Float.d.ts +7 -0
  37. package/build/cjs/components/Internal/Float/Float.js +1 -0
  38. package/build/cjs/components/Internal/Panel/Panel.d.ts +36 -0
  39. package/build/cjs/components/Internal/Panel/Panel.js +1 -0
  40. package/build/cjs/components/Internal/Panel/index.d.ts +2 -0
  41. package/build/cjs/components/Internal/Panel/index.js +1 -0
  42. package/build/cjs/components/Internal/Sandwich/-types.d.ts +36 -0
  43. package/build/cjs/components/Internal/Sandwich/-types.js +1 -0
  44. package/build/cjs/components/Internal/Sandwich/Sandwich.d.ts +23 -0
  45. package/build/cjs/components/Internal/Sandwich/Sandwich.js +1 -0
  46. package/build/cjs/components/Internal/Sandwich/SandwichBody.d.ts +3 -0
  47. package/build/cjs/components/Internal/Sandwich/SandwichBody.js +1 -0
  48. package/build/cjs/components/Internal/Sandwich/SandwichFooter.d.ts +3 -0
  49. package/build/cjs/components/Internal/Sandwich/SandwichFooter.js +1 -0
  50. package/build/cjs/components/Internal/Sandwich/SandwichHeader.d.ts +3 -0
  51. package/build/cjs/components/Internal/Sandwich/SandwichHeader.js +1 -0
  52. package/build/cjs/components/Internal/Sandwich/useSandwichContext.d.ts +12 -0
  53. package/build/cjs/components/Internal/Sandwich/useSandwichContext.js +1 -0
  54. package/build/cjs/components/Layout/-constants.d.ts +30 -0
  55. package/build/cjs/components/Layout/-constants.js +1 -0
  56. package/build/cjs/components/Layout/-types.d.ts +214 -0
  57. package/build/cjs/components/Layout/-types.js +1 -0
  58. package/build/cjs/components/Layout/Content.d.ts +7 -0
  59. package/build/cjs/components/Layout/Content.js +1 -0
  60. package/build/cjs/components/Layout/Layout.d.ts +17 -0
  61. package/build/cjs/components/Layout/Layout.js +1 -0
  62. package/build/cjs/components/Layout/LayoutProvider.d.ts +15 -0
  63. package/build/cjs/components/Layout/LayoutProvider.js +1 -0
  64. package/build/cjs/components/Layout/LayoutVars.d.ts +18 -0
  65. package/build/cjs/components/Layout/LayoutVars.js +1 -0
  66. package/build/cjs/components/Layout/RightPanel.d.ts +9 -0
  67. package/build/cjs/components/Layout/RightPanel.js +1 -0
  68. package/build/cjs/components/Layout/RightPanelContainer.d.ts +3 -0
  69. package/build/cjs/components/Layout/RightPanelContainer.js +1 -0
  70. package/build/cjs/components/Layout/Sidebar.d.ts +8 -0
  71. package/build/cjs/components/Layout/Sidebar.js +1 -0
  72. package/build/cjs/components/Layout/Split.d.ts +7 -0
  73. package/build/cjs/components/Layout/Split.js +1 -0
  74. package/build/cjs/components/Layout/context.d.ts +22 -0
  75. package/build/cjs/components/Layout/context.js +1 -0
  76. package/build/cjs/components/Layout/index.d.ts +9 -0
  77. package/build/cjs/components/Layout/index.js +1 -0
  78. package/build/cjs/components/Layout/reducer.d.ts +5 -0
  79. package/build/cjs/components/Layout/reducer.js +1 -0
  80. package/build/cjs/components/Layout/registry.d.ts +31 -0
  81. package/build/cjs/components/Layout/registry.js +1 -0
  82. package/build/cjs/components/Layout/store.d.ts +10 -0
  83. package/build/cjs/components/Layout/store.js +1 -0
  84. package/build/cjs/components/Layout/useLayout.d.ts +7 -0
  85. package/build/cjs/components/Layout/useLayout.js +1 -0
  86. package/build/cjs/components/Layout/usePanelRefs.d.ts +19 -0
  87. package/build/cjs/components/Layout/usePanelRefs.js +1 -0
  88. package/build/cjs/components/Layout/usePortalContainerRefs.d.ts +20 -0
  89. package/build/cjs/components/Layout/usePortalContainerRefs.js +1 -0
  90. package/build/cjs/components/Layout/varStore.d.ts +17 -0
  91. package/build/cjs/components/Layout/varStore.js +1 -0
  92. package/build/cjs/components/Lightbox/Lightbox.d.ts +1 -1
  93. package/build/cjs/components/NavBar/NavBarPrimaryNav.d.ts +4 -2
  94. package/build/cjs/components/NavBar/NavBarPrimaryNav.js +1 -1
  95. package/build/cjs/components/NavBar/NavBarSearchInput.d.ts +3 -2
  96. package/build/cjs/components/NavBar/NavBarSearchInput.js +1 -1
  97. package/build/cjs/components/NavBar/NavBarSecondaryNav.d.ts +5 -2
  98. package/build/cjs/components/NavBar/NavBarSecondaryNav.js +1 -1
  99. package/build/cjs/components/NavBar/NavBarSubMenuContainer.js +1 -1
  100. package/build/cjs/components/NavBar/constants.d.ts +1 -0
  101. package/build/cjs/components/NavBar/constants.js +1 -1
  102. package/build/cjs/components/Pagination/-types.d.ts +1 -1
  103. package/build/cjs/components/Patterns/EmptyState/EmptyState.d.ts +2 -2
  104. package/build/cjs/components/Patterns/EmptyState/EmptyState.js +1 -1
  105. package/build/cjs/components/PictogramButton/PictogramButton.d.ts +14 -5
  106. package/build/cjs/components/PictogramButton/PictogramButton.js +1 -1
  107. package/build/cjs/components/Portal/Portal.d.ts +1 -0
  108. package/build/cjs/components/Portal/Portal.js +1 -1
  109. package/build/cjs/components/ProgressBar/ProgressBar.d.ts +1 -1
  110. package/build/cjs/components/PromptInput/CategoryList.js +1 -1
  111. package/build/cjs/components/PromptInput/PromptTextArea.d.ts +1 -1
  112. package/build/cjs/components/SplashCardMedia/SplashCardMedia.d.ts +2 -2
  113. package/build/cjs/components/SplashCardMedia/SplashCardMedia.js +1 -1
  114. package/build/cjs/components/Typography/Header/Header.d.ts +1 -1
  115. package/build/cjs/components/Utilities/FloatingPosition/useFloatingPosition.d.ts +18 -4
  116. package/build/cjs/components/Utilities/FloatingPosition/useFloatingPosition.js +1 -1
  117. package/build/cjs/components/Utilities/FloatingPosition/utils.d.ts +6 -0
  118. package/build/cjs/components/Utilities/FloatingPosition/utils.js +1 -1
  119. package/build/cjs/index.d.ts +4 -0
  120. package/build/cjs/index.js +1 -1
  121. package/build/cjs/shared/mixins/Button/getAIButtonStyles.d.ts +7 -0
  122. package/build/cjs/shared/mixins/Button/getAIButtonStyles.js +4 -0
  123. package/build/cjs/types/a11y.d.ts +10 -8
  124. package/build/cjs/types/index.d.ts +15 -1
  125. package/build/cjs/types/index.js +1 -1
  126. package/build/cjs/types/type-helpers.d.ts +39 -0
  127. package/build/cjs/types/type-helpers.js +1 -0
  128. package/build/cjs/web-tokens/_colors.json +10 -0
  129. package/build/cjs/web-tokens/assets/icons.json +2 -1
  130. package/build/cjs/web-tokens/assets/icons16.json +1 -0
  131. package/build/cjs/web-tokens/visualConfig.d.ts +7 -0
  132. package/build/cjs/web-tokens/visualConfig.js +1 -1
  133. package/build/esm/components/AIButton/AIButton.js +1 -4
  134. package/build/esm/components/AIFloatingButton/AIFloatingButton.d.ts +10 -0
  135. package/build/esm/components/AIFloatingButton/AIFloatingButton.js +1 -0
  136. package/build/esm/components/AvatarGroup/AvatarGroup.d.ts +3 -3
  137. package/build/esm/components/AvatarGroup/AvatarGroup.js +1 -1
  138. package/build/esm/components/BinaryFeedback/-types.d.ts +1 -1
  139. package/build/esm/components/BulkActionsToolbar/BulkActionsToolbar.d.ts +1 -1
  140. package/build/esm/components/CatalogCard/CatalogCard.js +1 -1
  141. package/build/esm/components/ChatMessage/ChatMessage.d.ts +46 -0
  142. package/build/esm/components/ChatMessage/ChatMessage.js +1 -0
  143. package/build/esm/components/ChatMessage/index.d.ts +2 -0
  144. package/build/esm/components/ChatMessage/index.js +1 -0
  145. package/build/esm/components/ChatResponse/ChatResponse.d.ts +50 -0
  146. package/build/esm/components/ChatResponse/ChatResponse.js +1 -0
  147. package/build/esm/components/ChatResponse/constants.d.ts +7 -0
  148. package/build/esm/components/ChatResponse/constants.js +1 -0
  149. package/build/esm/components/ChatResponse/index.d.ts +2 -0
  150. package/build/esm/components/ChatResponse/index.js +1 -0
  151. package/build/esm/components/ColorPicker/ColorPicker.d.ts +1 -1
  152. package/build/esm/components/ColorPicker/ColorPickerDropdown.d.ts +1 -1
  153. package/build/esm/components/Content/ContentPictogramButton/ContentPictogramButton.d.ts +1 -1
  154. package/build/esm/components/Content/ContentTableModal/ContentTableModal.d.ts +1 -1
  155. package/build/esm/components/EntityList/BaseEntityList.js +1 -1
  156. package/build/esm/components/EntityList/VirtualizedEntityList.d.ts +3 -2
  157. package/build/esm/components/EntityList/roles.d.ts +9 -0
  158. package/build/esm/components/EntityList/roles.js +1 -0
  159. package/build/esm/components/EntityList/types.d.ts +24 -7
  160. package/build/esm/components/Form/SegmentedControl/-types.d.ts +3 -3
  161. package/build/esm/components/Form/ToolbarToggle/-types.d.ts +1 -1
  162. package/build/esm/components/Icon/Icon.d.ts +2 -2
  163. package/build/esm/components/Icon/Icon.js +1 -1
  164. package/build/esm/components/IconTile/IconTile.d.ts +1 -1
  165. package/build/esm/components/Image/Image.d.ts +13 -21
  166. package/build/esm/components/Image/Image.js +1 -1
  167. package/build/esm/components/Internal/BaseTag/BaseTag.d.ts +1 -1
  168. package/build/esm/components/Internal/Float/Float.d.ts +7 -0
  169. package/build/esm/components/Internal/Float/Float.js +1 -0
  170. package/build/esm/components/Internal/Panel/Panel.d.ts +36 -0
  171. package/build/esm/components/Internal/Panel/Panel.js +1 -0
  172. package/build/esm/components/Internal/Panel/index.d.ts +2 -0
  173. package/build/esm/components/Internal/Panel/index.js +1 -0
  174. package/build/esm/components/Internal/Sandwich/-types.d.ts +36 -0
  175. package/build/esm/components/Internal/Sandwich/-types.js +1 -0
  176. package/build/esm/components/Internal/Sandwich/Sandwich.d.ts +23 -0
  177. package/build/esm/components/Internal/Sandwich/Sandwich.js +1 -0
  178. package/build/esm/components/Internal/Sandwich/SandwichBody.d.ts +3 -0
  179. package/build/esm/components/Internal/Sandwich/SandwichBody.js +1 -0
  180. package/build/esm/components/Internal/Sandwich/SandwichFooter.d.ts +3 -0
  181. package/build/esm/components/Internal/Sandwich/SandwichFooter.js +1 -0
  182. package/build/esm/components/Internal/Sandwich/SandwichHeader.d.ts +3 -0
  183. package/build/esm/components/Internal/Sandwich/SandwichHeader.js +1 -0
  184. package/build/esm/components/Internal/Sandwich/useSandwichContext.d.ts +12 -0
  185. package/build/esm/components/Internal/Sandwich/useSandwichContext.js +1 -0
  186. package/build/esm/components/Layout/-constants.d.ts +30 -0
  187. package/build/esm/components/Layout/-constants.js +1 -0
  188. package/build/esm/components/Layout/-types.d.ts +214 -0
  189. package/build/esm/components/Layout/-types.js +1 -0
  190. package/build/esm/components/Layout/Content.d.ts +7 -0
  191. package/build/esm/components/Layout/Content.js +1 -0
  192. package/build/esm/components/Layout/Layout.d.ts +17 -0
  193. package/build/esm/components/Layout/Layout.js +1 -0
  194. package/build/esm/components/Layout/LayoutProvider.d.ts +15 -0
  195. package/build/esm/components/Layout/LayoutProvider.js +1 -0
  196. package/build/esm/components/Layout/LayoutVars.d.ts +18 -0
  197. package/build/esm/components/Layout/LayoutVars.js +1 -0
  198. package/build/esm/components/Layout/RightPanel.d.ts +9 -0
  199. package/build/esm/components/Layout/RightPanel.js +1 -0
  200. package/build/esm/components/Layout/RightPanelContainer.d.ts +3 -0
  201. package/build/esm/components/Layout/RightPanelContainer.js +1 -0
  202. package/build/esm/components/Layout/Sidebar.d.ts +8 -0
  203. package/build/esm/components/Layout/Sidebar.js +1 -0
  204. package/build/esm/components/Layout/Split.d.ts +7 -0
  205. package/build/esm/components/Layout/Split.js +1 -0
  206. package/build/esm/components/Layout/context.d.ts +22 -0
  207. package/build/esm/components/Layout/context.js +1 -0
  208. package/build/esm/components/Layout/index.d.ts +9 -0
  209. package/build/esm/components/Layout/index.js +1 -0
  210. package/build/esm/components/Layout/reducer.d.ts +5 -0
  211. package/build/esm/components/Layout/reducer.js +1 -0
  212. package/build/esm/components/Layout/registry.d.ts +31 -0
  213. package/build/esm/components/Layout/registry.js +1 -0
  214. package/build/esm/components/Layout/store.d.ts +10 -0
  215. package/build/esm/components/Layout/store.js +1 -0
  216. package/build/esm/components/Layout/useLayout.d.ts +7 -0
  217. package/build/esm/components/Layout/useLayout.js +1 -0
  218. package/build/esm/components/Layout/usePanelRefs.d.ts +19 -0
  219. package/build/esm/components/Layout/usePanelRefs.js +1 -0
  220. package/build/esm/components/Layout/usePortalContainerRefs.d.ts +20 -0
  221. package/build/esm/components/Layout/usePortalContainerRefs.js +1 -0
  222. package/build/esm/components/Layout/varStore.d.ts +17 -0
  223. package/build/esm/components/Layout/varStore.js +1 -0
  224. package/build/esm/components/Lightbox/Lightbox.d.ts +1 -1
  225. package/build/esm/components/NavBar/NavBarPrimaryNav.d.ts +4 -2
  226. package/build/esm/components/NavBar/NavBarPrimaryNav.js +1 -1
  227. package/build/esm/components/NavBar/NavBarSearchInput.d.ts +3 -2
  228. package/build/esm/components/NavBar/NavBarSearchInput.js +1 -1
  229. package/build/esm/components/NavBar/NavBarSecondaryNav.d.ts +5 -2
  230. package/build/esm/components/NavBar/NavBarSecondaryNav.js +1 -1
  231. package/build/esm/components/NavBar/NavBarSubMenuContainer.js +1 -1
  232. package/build/esm/components/NavBar/constants.d.ts +1 -0
  233. package/build/esm/components/NavBar/constants.js +1 -1
  234. package/build/esm/components/Pagination/-types.d.ts +1 -1
  235. package/build/esm/components/Patterns/EmptyState/EmptyState.d.ts +2 -2
  236. package/build/esm/components/Patterns/EmptyState/EmptyState.js +1 -1
  237. package/build/esm/components/PictogramButton/PictogramButton.d.ts +14 -5
  238. package/build/esm/components/PictogramButton/PictogramButton.js +1 -1
  239. package/build/esm/components/Portal/Portal.d.ts +1 -0
  240. package/build/esm/components/Portal/Portal.js +1 -1
  241. package/build/esm/components/ProgressBar/ProgressBar.d.ts +1 -1
  242. package/build/esm/components/PromptInput/CategoryList.js +1 -1
  243. package/build/esm/components/PromptInput/PromptTextArea.d.ts +1 -1
  244. package/build/esm/components/SplashCardMedia/SplashCardMedia.d.ts +2 -2
  245. package/build/esm/components/SplashCardMedia/SplashCardMedia.js +1 -1
  246. package/build/esm/components/Typography/Header/Header.d.ts +1 -1
  247. package/build/esm/components/Utilities/FloatingPosition/useFloatingPosition.d.ts +18 -4
  248. package/build/esm/components/Utilities/FloatingPosition/useFloatingPosition.js +1 -1
  249. package/build/esm/components/Utilities/FloatingPosition/utils.d.ts +6 -0
  250. package/build/esm/components/Utilities/FloatingPosition/utils.js +1 -1
  251. package/build/esm/index.d.ts +4 -0
  252. package/build/esm/index.js +1 -1
  253. package/build/esm/shared/mixins/Button/getAIButtonStyles.d.ts +7 -0
  254. package/build/esm/shared/mixins/Button/getAIButtonStyles.js +4 -0
  255. package/build/esm/types/a11y.d.ts +10 -8
  256. package/build/esm/types/index.d.ts +15 -1
  257. package/build/esm/types/index.js +1 -1
  258. package/build/esm/types/type-helpers.d.ts +39 -0
  259. package/build/esm/types/type-helpers.js +1 -0
  260. package/build/esm/web-tokens/_colors.json +10 -0
  261. package/build/esm/web-tokens/assets/icons.json +2 -1
  262. package/build/esm/web-tokens/assets/icons16.json +1 -0
  263. package/build/esm/web-tokens/visualConfig.d.ts +7 -0
  264. package/build/esm/web-tokens/visualConfig.js +1 -1
  265. package/build/scss/_dark.scss +1 -0
  266. package/build/scss/_light.scss +1 -0
  267. package/build/scss/_variables.scss +1 -0
  268. package/package.json +6 -4
  269. package/build/cjs/components/Content/ContentTableModal/ContentTableModal.mocks.d.ts +0 -3
  270. package/build/cjs/components/Content/ContentTableModal/ContentTableModal.mocks.js +0 -1
  271. package/build/cjs/components/EntityTree/treeListData.mock.d.ts +0 -3
  272. package/build/cjs/components/EntityTree/treeListData.mock.js +0 -1
  273. package/build/cjs/components/MediaViewerCarousel/MediaViewerCarousel.mocks.d.ts +0 -2
  274. package/build/cjs/components/MediaViewerCarousel/MediaViewerCarousel.mocks.js +0 -1
  275. package/build/esm/components/Content/ContentTableModal/ContentTableModal.mocks.d.ts +0 -3
  276. package/build/esm/components/Content/ContentTableModal/ContentTableModal.mocks.js +0 -1
  277. package/build/esm/components/EntityTree/treeListData.mock.d.ts +0 -3
  278. package/build/esm/components/EntityTree/treeListData.mock.js +0 -1
  279. package/build/esm/components/MediaViewerCarousel/MediaViewerCarousel.mocks.d.ts +0 -2
  280. package/build/esm/components/MediaViewerCarousel/MediaViewerCarousel.mocks.js +0 -1
@@ -1 +0,0 @@
1
- export const treeListData=[{id:"a",label:"a",children:[{id:"a.1",label:"a.1",children:[{id:"a.1.1",label:"a.1.1",children:[]},{id:"a.1.2",label:"a.1.2",children:[]}]}]},{id:"b",label:"b",children:[{id:"b.1",label:"b.1",children:[{id:"b.1.1",label:"b.1.1",children:[]}]}]}];export const hugeTreeData=[{type:"system",id:"L0/kf0mm2",label:"Human Development",children:[{type:"article",id:"kf0mm2/df0oO2",label:"Diphtheria",children:[{type:"question",id:"lT0vI2",label:"Recall the culture characteristics of Corynebacterium diphtheriae.",children:[]}]},{type:"article",id:"kf0mm2/Nf0-m2",label:"Listeriosis",children:[{type:"question",id:"k1amSj",label:"Recognize neonatal meningitis caused by Listeria monocytogenes, and recall its presentation in healthy adults.",children:[]}]},{type:"article",id:"kf0mm2/mf0V52",label:"Human immunodeficiency virus infection",children:[{type:"question",id:"ZeaZxj",label:"Recall the function of HIV protease inhibitors, and recall the impact of mutations on antiretroviral drug resistance.",children:[]},{type:"question",id:"b4aH3k",label:"Recall the mechanism of action of HIV fusion inhibitors.",children:[]}]},{type:"article",id:"kf0mm2/rf0fn2",label:"Candidiasis",children:[{type:"question",id:"dRaoN4",label:"Recognize the clinical presentation of a systemic Candida infection.",children:[]}]},{type:"article",id:"kf0mm2/Ff0gL2",label:"Helminth infections",children:[{type:"question",id:"TRa6m4",label:"Recognize Ascaris lumbricoides infection, and choose the most appropriate pharmacotherapy.",children:[]}]},{type:"article",id:"kf0mm2/yf0dK2",label:"Diarrheagenic E. coli",children:[{type:"question",id:"g1aFTj",label:"Recognize enterotoxigenic Escherichia coli infection, and recall the mechanism of its heat-labile toxin.",children:[]}]},{type:"article",id:"kf0mm2/Af0RK2",label:"Poisoning",children:[{type:"question",id:"oz00Fi",label:"Recognize cyanide poisoning from sodium nitroprusside use, and recall its antidote.",children:[]},{type:"question",id:"ZdaZoj",label:"Recognize Amanita phalloides poisoning, and recall its mechanism of hepatotoxicity.",children:[]}]},{type:"article",id:"kf0mm2/_f05K2",label:"Hospital-acquired infections",children:[{type:"question",id:"Fy0gSi",label:"Recall the mechanism of vancomycin resistance in Enterococcus faecalis.",children:[]},{type:"question",id:"hUac1P",label:"Recognize methicillin-resistant Staphylococcus aureus infection, and recall the mechanism of antibiotic resistance.",children:[]}]},{type:"article",id:"kf0mm2/YT0n62",label:"Gout and hyperuricemia",children:[{type:"question",id:"V3aGh4",label:"Recognize that elevated phosphoribosyl pyrophosphate synthetase activity is associated with gout.",children:[]}]},{type:"article",id:"kf0mm2/dT0op2",label:"Systemic lupus erythematosus",children:[{type:"question",id:"Yhanc4",label:"Recognize drug-induced lupus erythematosus, and recall the role of acetyltransferase activity in drug metabolism.",children:[]}]},{type:"article",id:"kf0mm2/mT0Vr2",label:"Hodgkin lymphoma",children:[{type:"question",id:"34aSQk",label:"Recognize Hodgkin lymphoma, and recall its characteristic cell markers.",children:[]}]},{type:"article",id:"kf0mm2/6T0j72",label:"Anemia",children:[{type:"question",id:"ty0XSi",label:"Recognize Fanconi anemia, and recall the associated genetic defect.",children:[]}]},{type:"article",id:"kf0mm2/8T0Os2",label:"Hemostasis and bleeding disorders",children:[{type:"question",id:"F1agij",label:"Recall the effect of broad-spectrum antibiotics on vitamin K levels and warfarin activity.",children:[]}]},{type:"article",id:"kf0mm2/Tg06u2",label:"Pheochromocytoma",children:[{type:"question",id:"fiakI4",label:"Recognize pheochromocytoma, and choose the most appropriate initial pharmacotherapy.",children:[]}]},{type:"article",id:"kf0mm2/4g03v2",label:"Obesity and metabolic syndrome",children:[{type:"question",id:"teaX0P",label:"Recognize metabolic syndrome, and recall its complications.",children:[]}]},{type:"article",id:"kf0mm2/Og0Iv2",label:"Acute kidney injury",children:[{type:"question",id:"MfaM5P",label:"Recognize acute tubular necrosis, and recall its common causes.",children:[]}]},{type:"article",id:"kf0mm2/dS0oA2",label:"Clostridioides difficile infection",children:[{type:"question",id:"6bajuQ",label:"Recognize Clostridium difficile infection, and recall the properties of effective disinfectants against its spores.",children:[]}]},{type:"article",id:"kf0mm2/fS0k_2",label:"Lynch syndrome",children:[{type:"question",id:"JA0ski",label:"Recognize Lynch syndrome, and recall the associated gene mutations.",children:[]}]},{type:"article",id:"kf0mm2/TS06_2",label:"Colorectal cancer",children:[{type:"question",id:"imaJ2O",label:"Choose the most appropriate health maintenance recommendation for colorectal cancer screening in asymptomatic adults.",children:[]}]},{type:"article",id:"kf0mm2/3S0Sz2",label:"Pancreatic cancer",children:[{type:"question",id:"Nja-0k",label:"Recognize the increased risk for specific malignancies associated with long-term tobacco smoking.",children:[]}]},{type:"article",id:"kf0mm2/kS0m-2",label:"Hepatitis A",children:[{type:"question",id:"D301kf",label:"Choose the most appropriate vaccine for a patient traveling to Mexico.",children:[]}]},{type:"article",id:"kf0mm2/OS0I-2",label:"Hepatitis B",children:[{type:"question",id:"PQ0Wwf",label:"Choose the appropriate postexposure prophylaxis for hepatitis B in non-responders to the vaccine.",children:[]},{type:"question",id:"AKaRQl",label:"Recognize the need for hepatitis B screening in individuals from high-prevalence areas, and choose the most appropriate screening test.",children:[]}]},{type:"article",id:"kf0mm2/IS0Yaf",label:"Wilson disease",children:[{type:"question",id:"Jeas-j",label:"Recall the inheritance pattern of Wilson disease, and recall the associated risk for offspring when both parents are carriers.",children:[]}]},{type:"article",id:"kf0mm2/Ph0WVf",label:"Asthma",children:[{type:"question",id:"uOap8k",label:"Choose the pharmacotherapy for asthma that leads to downregulation of the high-affinity IgE receptor.",children:[]}]},{type:"article",id:"kf0mm2/5h0ief",label:"Tuberculosis",children:[{type:"question",id:"24aTik",label:"Recognize reactivated pulmonary tuberculosis, and recall the cell surface markers of macrophages.",children:[]}]},{type:"article",id:"kf0mm2/nh07ef",label:"Lung cancer",children:[{type:"question",id:"Ay0R3i",label:"Recognize lung adenocarcinoma, and recall the associated genetic mutations.",children:[]},{type:"question",id:"m8aVMm",label:"Choose the most appropriate screening study for lung cancer in a former smoker with a significant smoking history.",children:[]}]},{type:"article",id:"kf0mm2/Kh0UUf",label:"Wound healing",children:[{type:"question",id:"VRaGN4",label:"Recall the role of myofibroblasts in wound healing and contracture formation.",children:[]},{type:"question",id:"nKa7Sl",label:"Recognize a hypertrophic scar, and recall the role of transforming growth factor-beta in wound healing.",children:[]}]},{type:"article",id:"kf0mm2/qh0CUf",label:"Skin and soft tissue infections",children:[{type:"question",id:"FB0gci",label:"Recognize ecthyma gangrenosum, and recall its associated virulence factor.",children:[]}]},{type:"article",id:"kf0mm2/V30Ghf",label:"Cholelithiasis",children:[{type:"question",id:"9faNoP",label:"Recognize acute cholangitis, and recall the cause of brown pigment gallstones.",children:[]}]},{type:"article",id:"kf0mm2/C30qkf",label:"Parkinson disease",children:[{type:"question",id:"-9aDJ5",label:"Choose the most appropriate management for an elderly individual who experiences frequent falls.",children:[]}]},{type:"article",id:"kf0mm2/ZR0Zlf",label:"Meningitis",children:[{type:"question",id:"_L05ZS",label:"Recognize meningococcal meningitis, and choose the appropriate vaccine to prevent this infection.",children:[]}]},{type:"article",id:"kf0mm2/HR0Kof",label:"Shingles",children:[{type:"question",id:"Vi0Gqf",label:"Choose the most appropriate vaccine for an immunocompetent adult over 50 years of age.",children:[]}]},{type:"article",id:"kf0mm2/uR0pKf",label:"Myotonic syndromes",children:[{type:"question",id:"fcakbj",label:"Recognize myotonic muscular dystrophy type 1, and recall the genetic property of anticipation.",children:[]}]},{type:"article",id:"kf0mm2/vR0AKf",label:"Inborn errors of metabolism",children:[{type:"question",id:"uVapwj",label:"Recognize alkaptonuria, and recall its associated metabolic defect.",children:[]},{type:"question",id:"HjaKbk",label:"Recognize methylmalonic acidemia, and recall the enzyme deficiency it involves.",children:[]}]},{type:"article",id:"kf0mm2/li0v7f",label:"Polycystic kidney disease",children:[{type:"question",id:"-faDKP",label:"Recognize autosomal dominant polycystic kidney disease, and recall its genetic defect locations.",children:[]}]},{type:"article",id:"kf0mm2/WQ0PEf",label:"Infection prevention and control",children:[{type:"question",id:"GA0BOi",label:"Choose the most effective strategy to decrease the risk of central-line associated bloodstream infections.",children:[]},{type:"question",id:"-WaDLj",label:"Recall the resistance of prions to standard sterilization methods.",children:[]},{type:"question",id:"xkaEJk",label:"Recall the characteristics of nonenveloped viruses, and recall the disinfectants effective against them.",children:[]},{type:"question",id:"0maeVO",label:"Recall the mechanism of action of hydrogen peroxide as a disinfectant.",children:[]},{type:"question",id:"tqaXZN",label:"Recognize the limitations of chlorhexidine, and recall the characteristics of Clostridium tetani.",children:[]}]},{type:"article",id:"kf0mm2/HQ0Kxf",label:"Malignant bone tumors",children:[{type:"question",id:"GK0B3S",label:"Recognize growing pains, and choose the most appropriate management.",children:[]}]},{type:"article",id:"kf0mm2/FQ0gBf",label:"Paget disease of bone",children:[{type:"question",id:"R2alhP",label:"Recognize Paget disease of the bone, and recall its molecular pathophysiology.",children:[]}]},{type:"article",id:"kf0mm2/AQ0RAf",label:"Metal toxicity",children:[{type:"question",id:"ZJ0ZsS",label:"Recognize acute iron poisoning, and choose the appropriate chelation therapy.",children:[]}]},{type:"article",id:"kf0mm2/sj0tbT",label:"Sinusitis",children:[{type:"question",id:"ZTaZ6P",label:"Recognize Kartagener syndrome, and recall the function of ciliated columnar cells.",children:[]}]},{type:"article",id:"kf0mm2/dP0odT",label:"Pathology techniques",children:[{type:"question",id:"bhaHc4",label:"Recognize the clinical application of flow cytometry, and recall the diagnostic findings for paroxysmal nocturnal hemoglobinuria.",children:[]},{type:"question",id:"xNaEWO",label:"Recognize Nocardia asteroides as a weakly acid-fast organism.",children:[]}]},{type:"article",id:"kf0mm2/VP0GdT",label:"Cellular changes and adaptive responses",children:[{type:"question",id:"8A0Oli",label:"Recall the type of necrosis associated with brain infarcts.",children:[]},{type:"question",id:"UiabI4",label:"Recognize features of apoptosis, and recall the role of mitochondrial cytochrome c.",children:[]},{type:"question",id:"P4aWjk",label:"Recall the histological features of anaplasia in thyroid cells.",children:[]},{type:"question",id:"44a3jk",label:"Recall the role of caspases in apoptosis, and recognize thymic involution.",children:[]},{type:"question",id:"8OaO8k",label:"Recall the mechanism of apoptosis induced by cytotoxic T cells.",children:[]},{type:"question",id:"WlaPDk",label:"Recognize acute diverticulitis with abscess formation, and recall the role of lysosomal enzymes in suppurative inflammation.",children:[]},{type:"question",id:"55aikO",label:"Recognize chronic pancreatitis, and recall the concept of dystrophic calcification.",children:[]},{type:"question",id:"bMaHMO",label:"Recognize acute kidney injury, and recall the reversible cellular changes due to hypoxic injury.",children:[]},{type:"question",id:"F6ag5l",label:"Recognize brain ischemia, and recall the effects of ATP depletion on cells.",children:[]}]},{type:"article",id:"kf0mm2/HP0KTT",label:"Elimination disorders",children:[{type:"question",id:"Fo0gdS",label:"Recognize the normalcy of nocturnal enuresis in children under 5 years old, and choose the most appropriate management.",children:[]}]},{type:"article",id:"kf0mm2/tP0XgT",label:"Sleep and sleep disorders",children:[{type:"question",id:"zL0rZS",label:"Choose the most appropriate next step in management for an elderly patient with changes in sleep architecture.",children:[]}]},{type:"article",id:"kf0mm2/b40H3T",label:"Child development and milestones",children:[{type:"question",id:"fK0kfS",label:"Recall developmental milestones in a 13-month-old.",children:[]},{type:"question",id:"YJ0nsS",label:"Recall developmental milestones in a 3-year-old.",children:[]},{type:"question",id:"WJ0PGS",label:"Recognize delayed fine motor development in an infant.",children:[]},{type:"question",id:"Uq0bBS",label:"Recognize the developmental milestones of a 2-month-old infant.",children:[]},{type:"question",id:"2q0TBS",label:"Recall developmental milestones in a 2-year-old.",children:[]},{type:"question",id:"dhao14",label:"Recall developmental milestones in a 2-year-old.",children:[]},{type:"question",id:"CJaqwl",label:"Recognize that developmental milestones can vary between twins and reassure accordingly.",children:[]},{type:"question",id:"gGaFAN",label:"Recognize delayed gross motor development in infants.",children:[]}]},{type:"article",id:"kf0mm2/U40biT",label:"Down syndrome",children:[{type:"question",id:"HaaKNQ",label:"Recognize the clinical features of Down syndrome, and recall the genetic mechanisms that can lead to this condition.",children:[]}]},{type:"article",id:"kf0mm2/240TiT",label:"Rare inherited syndromes",children:[{type:"question",id:"beaHxj",label:"Recognize Zellweger syndrome, and recall its cellular pathology.",children:[]},{type:"question",id:"ejaxz4",label:"Recognize Angelman syndrome, and recall its genetic mechanisms.",children:[]}]},{type:"article",id:"kf0mm2/T406iT",label:"Sudden infant death syndrome",children:[{type:"question",id:"xCaE85",label:"Recognize the appropriate use and timing of pacifier introduction to prevent SIDS.",children:[]}]},{type:"article",id:"kf0mm2/Q40uQT",label:"Vitamin K deficiency bleeding of the newborn",children:[{type:"question",id:"Rialr4",label:"Recognize the risk of hemorrhagic disease in newborns, and choose the appropriate supplement to prevent it.",children:[]}]},{type:"article",id:"kf0mm2/L40wPT",label:"Cystic fibrosis",children:[{type:"question",id:"iJ0JFS",label:"Choose the appropriate management for vitamin A deficiency.",children:[]},{type:"question",id:"g0aF2Q",label:"Recognize cystic fibrosis, and recall the molecular basis of its pathophysiology.",children:[]},{type:"question",id:"JNasXO",label:"Recognize cystic fibrosis, and recall the function of the CFTR gene.",children:[]}]},{type:"article",id:"kf0mm2/D401lT",label:"Febrile seizures",children:[{type:"question",id:"QRau54",label:"Recognize simple febrile seizures, and recall the mechanism of action of antipyretics.",children:[]}]},{type:"article",id:"kf0mm2/940NlT",label:"Neuroblastoma",children:[{type:"question",id:"vIaAeN",label:"Recognize neuroblastoma, and recall its genetic alterations.",children:[]}]},{type:"article",id:"kf0mm2/ak0QmT",label:"Impetigo",children:[{type:"question",id:"h_0cLi",label:"Recognize bullous impetigo, and recall its underlying cause.",children:[]}]},{type:"article",id:"kf0mm2/mk0VoT",label:"Porphyrias",children:[{type:"question",id:"4Va3uj",label:"Recognize acute intermittent porphyria, and recall its inheritance pattern.",children:[]}]},{type:"article",id:"kf0mm2/sk0t6T",label:"Syphilis",children:[{type:"question",id:"ZA0ZRi",label:"Recognize secondary syphilis, and choose the most appropriate confirmatory test.",children:[]}]},{type:"article",id:"kf0mm2/_k05qT",label:"Breast cancer",children:[{type:"question",id:"VVaGtj",label:"Recognize Li-Fraumeni syndrome, and recall the genetic principle of loss of heterozygosity.",children:[]}]},{type:"article",id:"kf0mm2/oO00tT",label:"Keratitis",children:[{type:"question",id:"Hy0Kgi",label:"Recognize bacterial keratitis in contact lens users, and recall the typical causative organism.",children:[]}]},{type:"article",id:"kf0mm2/IO0YFT",label:"Glaucoma",children:[{type:"question",id:"b3aHS4",label:"Recognize the side effects of prostaglandin F2α analogs used in glaucoma therapy.",children:[]}]},{type:"article",id:"kf0mm2/zO0rET",label:"Human papillomavirus infection",children:[{type:"question",id:"qKaChl",label:"Recognize anal cancer associated with HPV, and recall the role of p53 protein inactivation in its pathogenesis.",children:[]}]},{type:"article",id:"kf0mm2/Vl0GDT",label:"Staphylococcal diseases",children:[{type:"question",id:"4Ua3WP",label:"Recognize toxic shock syndrome, and recall the function of Staphylococcus aureus protein A.",children:[]}]},{type:"article",id:"kf0mm2/ol00BT",label:"Tumor markers",children:[{type:"question",id:"k2am3P",label:"Recall the immunohistochemical markers for neuronal origin tumors.",children:[]},{type:"question",id:"1Qa2E4",label:"Recognize cytokeratin-positive lymph node metastasis from a skin primary neoplasm.",children:[]},{type:"question",id:"4Oa3sk",label:"Recognize rhabdomyosarcoma by positive desmin staining.",children:[]}]},{type:"article",id:"kf0mm2/7N04cg",label:"Fundamentals of pharmacology",children:[{type:"question",id:"5j0iaT",label:"Calculate the volume of distribution of a drug.",children:[]},{type:"question",id:"ux0pyR",label:"Recall drug interactions that may increase warfarin bioavailability and cause toxicity.",children:[]},{type:"question",id:"rA0fOi",label:"Choose the correct maintenance dose calculation for oral antibiotics with known clearance and bioavailability.",children:[]},{type:"question",id:"bz0Hri",label:"Recognize first order kinetics, and recall the drug concentration after multiple half-lives.",children:[]},{type:"question",id:"1z027i",label:"Recall the concept of bioavailability, and recognize its implications on drug administration routes.",children:[]},{type:"question",id:"B1azQj",label:"Recall the effects of competitive antagonists on dose-response curves.",children:[]},{type:"question",id:"y1adjj",label:"Recall the Michaelis-Menten plot curve that represents an allosteric effect.",children:[]},{type:"question",id:"_Wa5Lj",label:"Recall the concept of drug efficacy in the context of partial versus full agonists.",children:[]},{type:"question",id:"4ha3V4",label:"Recognize a stroke, and recall drug interactions that may lead to subtherapeutic anticoagulation in patients on warfarin.",children:[]},{type:"question",id:"7Pa4Tk",label:"Recognize isoniazid hepatitis, and recall the pharmacokinetic process of acetylation.",children:[]},{type:"question",id:"_Oa5Ek",label:"Recall the effect of CYP3A4 inhibitors on statin metabolism.",children:[]},{type:"question",id:"6lajBk",label:"Recognize hepatocellular carcinoma associated with aflatoxin exposure, and recall the role of cytochrome P450 monooxygenases in its pathogenesis.",children:[]},{type:"question",id:"WIaPbN",label:"Recall the concept of drug potentiation, and recall the role of CYP3A4 in drug metabolism.",children:[]},{type:"question",id:"KraURN",label:"Recognize permissive drug interactions, and choose drugs that enhance the effect of bronchodilators in asthma.",children:[]}]},{type:"article",id:"kf0mm2/tN0X1g",label:"Sympathomimetic drugs",children:[{type:"question",id:"feakyj",label:"Recall the effects of β2 receptor agonists.",children:[]},{type:"question",id:"gPaFVk",label:"Recall the therapeutic use of selective alpha-1 agonists for nasal congestion.",children:[]}]},{type:"article",id:"kf0mm2/uN0p1g",label:"Beta blockers",children:[{type:"question",id:"8paOrl",label:"Recognize a hypertensive emergency, and choose the appropriate antihypertensive therapy.",children:[]}]},{type:"article",id:"kf0mm2/EN081g",label:"Inhalational anesthetics",children:[{type:"question",id:"tXaX-Q",label:"Recall the impact of anesthetic lipid solubility on emergence from anesthesia in obese patients.",children:[]},{type:"question",id:"jTa_qP",label:"Recall the relationship between MAC, blood-gas partition coefficient, and anesthetic potency and recovery time.",children:[]}]},{type:"article",id:"kf0mm2/vN0A1g",label:"Intravenous anesthetics",children:[{type:"question",id:"tjaXXk",label:"Recall the effects of NMDA receptor antagonists, and recall the neurotransmitter glutamate's role in anesthesia.",children:[]},{type:"question",id:"hnacGO",label:"Recall the concept of drug redistribution and its effect on anesthetic recovery.",children:[]}]},{type:"article",id:"kf0mm2/DN01Wg",label:"Skeletal muscle relaxants",children:[{type:"question",id:"_na5DO",label:"Recall the unique elimination properties of atracurium.",children:[]}]},{type:"article",id:"kf0mm2/CN0qWg",label:"Sedative-hypnotic drugs",children:[{type:"question",id:"g6aF4l",label:"Recall the mechanism of action of benzodiazepines in status epilepticus.",children:[]}]},{type:"article",id:"kf0mm2/BN0zWg",label:"Non-opioid analgesics",children:[{type:"question",id:"ldavJj",label:"Recognize drug interactions that reduce the efficacy of loop diuretics.",children:[]}]},{type:"article",id:"kf0mm2/yN0ddg",label:"Opioids",children:[{type:"question",id:"ujapXk",label:"Recall the side effects of long-term opioid therapy that do not diminish with tolerance.",children:[]},{type:"question",id:"KPaUfk",label:"Recognize opioid withdrawal, and recall the effects of partial opioid agonists.",children:[]}]},{type:"article",id:"kf0mm2/Ym0nVg",label:"Second-line lipid-lowering agents",children:[{type:"question",id:"Iy0Ygi",label:"Recall the mechanism of action of gemfibrozil.",children:[]}]},{type:"article",id:"kf0mm2/Um0bUg",label:"Antiplatelet agents",children:[{type:"question",id:"tUaXUP",label:"Recognize Reye syndrome, and recall the effects of aspirin on uric acid elimination.",children:[]},{type:"question",id:"PiaW74",label:"Recall the mechanism of action of aspirin.",children:[]}]},{type:"article",id:"kf0mm2/2m0TUg",label:"Parenteral anticoagulation",children:[{type:"question",id:"z4arNk",label:"Recognize the pharmacodynamics of medications used in the treatment of pulmonary embolism.",children:[]}]},{type:"article",id:"kf0mm2/gm0FUg",label:"Diuretics",children:[{type:"question",id:"Tu06q3",label:"",children:[]},{type:"question",id:"Qz0usi",label:"",children:[]}]},{type:"article",id:"kf0mm2/4m03fg",label:"Chemotherapeutic agents",children:[{type:"question",id:"hw0ciR",label:"Recall the mechanism of action of 5-fluorouracil, and events in specific cell cycle stages.",children:[]},{type:"question",id:"fy0kei",label:"Recall the mechanism of action of paclitaxel.",children:[]},{type:"question",id:"Pz0WGi",label:"Recall the mechanism of action of platinum-based chemotherapeutic agents, and recognize their ototoxic side effects.",children:[]},{type:"question",id:"54aiPk",label:"Recall the mechanism of action and adverse effects of bleomycin, and its effect on the cell cycle.",children:[]},{type:"question",id:"u4apOk",label:"Recall the mechanism of action of teniposide.",children:[]},{type:"question",id:"_4a5Nk",label:"Recall the mechanism of action of topoisomerase I inhibitors.",children:[]},{type:"question",id:"1ka25k",label:"Recall the mechanism of action and dietary considerations for antimetabolite chemotherapeutic agents.",children:[]},{type:"question",id:"PkaWLk",label:"Recognize hairy cell leukemia, and recall the mechanism of action of its first-line treatment.",children:[]}]},{type:"article",id:"kf0mm2/mm0VTg",label:"Overview of antibiotic therapy",children:[{type:"question",id:"vA0Ali",label:"Recall the mechanism of antistaphylococcal penicillins, and recall the common causes of folliculitis.",children:[]},{type:"question",id:"xA0ENi",label:"Recall the adverse effects associated with antibiotics that disrupt cell membranes.",children:[]},{type:"question",id:"pWaLmj",label:"Recall the mechanism of oxacillin resistance in Staphylococcus aureus.",children:[]},{type:"question",id:"CWaqnj",label:"Recognize spontaneous bacterial peritonitis, and recall the microbial coverage and mechanism of action of cephalosporins.",children:[]},{type:"question",id:"WdaPKj",label:"Recognize Rocky Mountain spotted fever, and recall the mechanism of action of chloramphenicol.",children:[]},{type:"question",id:"WVaPtj",label:"Recall the mechanisms of fluoroquinolone resistance in bacteria.",children:[]},{type:"question",id:"7Ua4eP",label:"Recognize anaplasmosis, and recall the mechanism of action of doxycycline.",children:[]},{type:"question",id:"S2aySP",label:"Recall the effect of polyvalent cations on fluoroquinolone absorption.",children:[]},{type:"question",id:"T3a634",label:"Recognize the effects of in utero tetracycline exposure.",children:[]},{type:"question",id:"rjafbk",label:"Recall the mechanism of resistance to aminoglycosides.",children:[]},{type:"question",id:"3kaSnk",label:"Recognize primary syphilis, and recall the mechanism of action of penicillin G.",children:[]},{type:"question",id:"EOa88k",label:"Recall the mechanism of action and intracellular activity of pyrazinamide.",children:[]},{type:"question",id:"Ela8Ak",label:"Recognize aminoglycoside-penicillin synergy, and recall its mechanism.",children:[]},{type:"question",id:"hNacaO",label:"Recall the mechanism of action of rifampin, and recall the process of RNA synthesis from DNA.",children:[]},{type:"question",id:"N5a-4O",label:"Recall the mechanism of action of bleomycin, and recall the mechanism of action of metronidazole.",children:[]},{type:"question",id:"kMamKO",label:"Recognize metronidazole adverse effects, and recall the pathogens it treats.",children:[]},{type:"question",id:"YLanwO",label:"Recall the effects of beta-lactam antibiotics on bacterial cell walls, and recall the characteristics of gram-positive bacteria.",children:[]},{type:"question",id:"jra_SN",label:"Choose the characteristic of pharmacotherapy for Clostridium difficile infection.",children:[]}]},{type:"article",id:"kf0mm2/6m0jgg",label:"Antifungals",children:[{type:"question",id:"YaanQQ",label:"Recall the effect of gastric pH on drug absorption.",children:[]},{type:"question",id:"xlaE_k",label:"Recognize theophylline toxicity, and recall drug interactions with cytochrome P450 inhibitors.",children:[]}]},{type:"article",id:"kf0mm2/pm0Lgg",label:"Antiviral agents",children:[{type:"question",id:"KA0Uki",label:"Recognize herpes simplex virus infection in an immunocompromised patient, and choose an antiviral treatment that does not require viral kinase activation.",children:[]},{type:"question",id:"rXafzQ",label:"Recognize treatment for chronic hepatitis C, and recall the mechanism of action of ribavirin.",children:[]},{type:"question",id:"ucapVj",label:"Recognize foscarnet-induced hypocalcemia.",children:[]},{type:"question",id:"U4abik",label:"Recall drug interactions that increase the risk of myelosuppression with antiretroviral therapy.",children:[]},{type:"question",id:"TOa67k",label:"Recall the activation mechanism of guanosine analog antivirals, and recall their selective toxicity in virally infected cells.",children:[]}]},{type:"article",id:"kf0mm2/qm0Cgg",label:"Antiemetics",children:[{type:"question",id:"Uv0bz3",label:"Recognize chemotherapy-induced nausea and vomiting, and recall the side effects of 5-HT3 antagonists.",children:[]}]},{type:"article",id:"kf0mm2/7m04Sg",label:"Antidiabetic drugs",children:[{type:"question",id:"i0aJfQ",label:"Recall the mechanism of action of insulin secretagogues, and recall the regulation of insulin release from pancreatic beta cells.",children:[]},{type:"question",id:"9XaNZj",label:"Recall the mechanism of action of metformin in type 2 diabetes mellitus.",children:[]},{type:"question",id:"LWawNj",label:"Recall the mechanism of action of alpha-glucosidase inhibitors in the treatment of diabetes mellitus.",children:[]},{type:"question",id:"jma_2O",label:"Recall the mechanism of action of meglitinides and sulfonylureas.",children:[]}]},{type:"article",id:"kf0mm2/Gm0BSg",label:"Insulin",children:[{type:"question",id:"IXaYzQ",label:"Recall the effects of insulin on gluconeogenesis, and recall the role of fructose-1,6-bisphosphatase.",children:[]}]},{type:"article",id:"kf0mm2/Bm0z3g",label:"Influenza",children:[{type:"question",id:"ii0Jrf",label:"Recognize early influenza in high-risk patients, and choose the most appropriate antiviral therapy.",children:[]},{type:"question",id:"Fi0gtf",label:"Choose the most appropriate health maintenance recommendation for a patient with diabetes during flu season.",children:[]},{type:"question",id:"9i0NFf",label:"Choose the appropriate influenza vaccine for a patient with a history of egg allergy.",children:[]},{type:"question",id:"Tca6bj",label:"Recognize influenza virus infection, and recall the mechanism of action of neuraminidase inhibitors.",children:[]}]},{type:"article",id:"kf0mm2/_m05Rg",label:"Vaccination",children:[{type:"question",id:"cj0azf",label:"Recognize precautions for DTaP vaccine administration, and choose the condition that supports deferring the vaccine.",children:[]},{type:"question",id:"2NaT0O",label:"Recall the target pathogen of the Haemophilus influenzae type b vaccine.",children:[]},{type:"question",id:"oHa0rN",label:"Choose the appropriate immunization recommendation for a child with mild acute illness.",children:[]},{type:"question",id:"wBah1M",label:"Recall the mechanism of action of mRNA vaccines.",children:[]}]},{type:"article",id:"kf0mm2/zm0rRg",label:"Immunization schedule",children:[{type:"question",id:"LQ0w9f",label:"Choose the most appropriate health maintenance recommendation for patients traveling to the southern hemisphere.",children:[]},{type:"question",id:"7Q04xf",label:"Choose the most appropriate vaccine for an immunocompromised older adult.",children:[]},{type:"question",id:"HQ0Kxf",label:"Choose the appropriate timing for DTaP vaccination in preterm infants.",children:[]},{type:"question",id:"OqaIAl",label:"Choose the most appropriate vaccinations for a young healthy adult.",children:[]}]},{type:"article",id:"kf0mm2/x50Emg",label:"Adaptive immune system",children:[{type:"question",id:"URabm4",label:"Recall the immunophenotype of mature cytotoxic T lymphocytes.",children:[]},{type:"question",id:"vRaAK4",label:"Recall the process of positive selection of T cells in the thymus.",children:[]}]},{type:"article",id:"kf0mm2/y50d5g",label:"Basics of human genetics",children:[{type:"question",id:"JB0sbi",label:"Recognize G6PD deficiency inheritance, and recall its probability calculation.",children:[]},{type:"question",id:"6y0jTi",label:"Recognize Tay-Sachs disease, and recall the effects of frameshift mutations.",children:[]},{type:"question",id:"LA0w4i",label:"Recognize phenylketonuria, and calculate the carrier status probability for an autosomal recessive disease.",children:[]},{type:"question",id:"KcaUWj",label:"Recognize Klinefelter syndrome, and recall the mechanism of X chromosome inactivation.",children:[]},{type:"question",id:"JcasWj",label:"Recall the inheritance pattern of Kartagener syndrome, and recall how to calculate the probability of offspring being affected using Mendelian principles and the Hardy-Weinberg law.",children:[]},{type:"question",id:"L1awhj",label:"Recall the concept of variable expressivity in genetics.",children:[]},{type:"question",id:"XWa9Pj",label:"Recall the concept of confined placental mosaicism.",children:[]},{type:"question",id:"i4aJQk",label:"Recall the characteristics of X-linked recessive inheritance.",children:[]},{type:"question",id:"GlaByk",label:"Recall the Hardy-Weinberg principle, and calculate the probability of an autosomal recessive disease.",children:[]},{type:"question",id:"Jpasql",label:"Recall the characteristics of multifactorial (polygenic) inheritance.",children:[]},{type:"question",id:"0IaeYN",label:"Recognize meningocele as a multifactorial inheritance disorder, and recall how recurrence risk correlates with affected relatives.",children:[]}]},{type:"article",id:"kf0mm2/WM0Png",label:"General oncology",children:[{type:"question",id:"4ca3cj",label:"Recall the components of tumor grading systems.",children:[]},{type:"question",id:"E1a8ij",label:"Recall the role of matrix metalloproteinases in cancer metastasis.",children:[]},{type:"question",id:"pgaLwP",label:"Recognize villous adenomas, and recall the role of β-catenin in their pathogenesis.",children:[]},{type:"question",id:"2RaTm4",label:"Recognize squamous cell carcinoma of the lung, and recall factors affecting prognosis.",children:[]},{type:"question",id:"l4avjk",label:"Recall the histopathological features of carcinoma in situ.",children:[]},{type:"question",id:"I4aYkk",label:"Recall the role of P-glycoprotein in multidrug resistance.",children:[]}]},{type:"article",id:"kf0mm2/QM0uog",label:"Food allergies",children:[{type:"question",id:"Xq09CS",label:"Recognize infantile colic, and choose the most appropriate next step in management.",children:[]}]},{type:"article",id:"kf0mm2/qM0Cpg",label:"Immunosuppressants",children:[{type:"question",id:"fUakcP",label:"Recognize ankylosing spondylitis, and recall the mechanism of action of TNF-α inhibitors.",children:[]},{type:"question",id:"P3aWi4",label:"Recall the mechanism of action of azathioprine, and recall the role of hypoxanthine-guanine phosphoribosyl transferase in purine metabolism.",children:[]},{type:"question",id:"R4alQk",label:"Recall the indications for trastuzumab, and recall its mechanism of action.",children:[]},{type:"question",id:"ckaa5k",label:"Recall the mechanism of action of bevacizumab.",children:[]},{type:"question",id:"7Ma4JO",label:"Recall the indications for bevacizumab, and recall its contraindications.",children:[]}]},{type:"article",id:"kf0mm2/FM0gqg",label:"Cleft lip and cleft palate",children:[{type:"question",id:"vz0Aui",label:"Recall the embryological origin of cleft lip.",children:[]}]},{type:"article",id:"kf0mm2/Sn0ysg",label:"Bacteria overview",children:[{type:"question",id:"T_06ni",label:"Recognize bacterial tonsillopharyngitis caused by GAS, and recall the role of M protein in inhibiting phagocytosis.",children:[]},{type:"question",id:"IdaYrj",label:"Recognize Bacteroides fragilis infection, and recall its common habitat in the human body.",children:[]},{type:"question",id:"J2asiP",label:"Recognize Pseudomonas aeruginosa infection in burn wounds, and recall its virulence factors.",children:[]},{type:"question",id:"HSaKa4",label:"Recognize Staphylococcus epidermidis infection, and recall its major virulence factor.",children:[]},{type:"question",id:"0Qaeu4",label:"Recognize otitis media caused by Haemophilus influenzae, and recall the mechanism of its virulence factor.",children:[]},{type:"question",id:"hjacZk",label:"Recognize lobar pneumonia, and recall the virulence factors of Streptococcus pneumoniae.",children:[]},{type:"question",id:"qjaCYk",label:"Recall the microbiological properties of Haemophilus influenzae, and recall infections that can be prevented by Hib vaccination.",children:[]},{type:"question",id:"9kaNJk",label:"Recognize the use of Thayer-Martin agar, and recall the condition it isolates.",children:[]},{type:"question",id:"5OaiGk",label:"Recognize Klebsiella pneumoniae as a cause of nosocomial acute pyelonephritis.",children:[]},{type:"question",id:"HNaKcO",label:"Recall the characteristics of bacteria without a cell wall.",children:[]},{type:"question",id:"CMaqIO",label:"Recognize catheter-related bloodstream infections, and choose the most appropriate empiric antibiotic therapy.",children:[]},{type:"question",id:"f6ak4l",label:"Recognize Pseudomonas aeruginosa burn wound infection, and recall the mechanism of its exotoxin.",children:[]}]},{type:"article",id:"kf0mm2/Pn0Wtg",label:"General virology",children:[{type:"question",id:"Xu09p3",label:"Recognize rhinovirus as a cause of the common cold, and recall its cellular receptor for virulence.",children:[]},{type:"question",id:"1aa2jQ",label:"Recall the concept of viral recombination.",children:[]},{type:"question",id:"WaaPjQ",label:"Recall the concept of phenotypic mixing in viruses.",children:[]},{type:"question",id:"_Ya57Q",label:"Recognize viral reassortment, and recall its occurrence in segmented RNA viruses.",children:[]},{type:"question",id:"qPaCfk",label:"Recall the virulence factor of parvovirus B19.",children:[]},{type:"question",id:"C4aqlk",label:"Recognize herpetic whitlow, and recall the structure of herpes simplex virus.",children:[]},{type:"question",id:"B4azlk",label:"Recognize adult T-cell leukemia, and recall the properties of its causal virus.",children:[]},{type:"question",id:"hkacnk",label:"Recognize the characteristics of herpesviruses, and recall the conditions they can cause.",children:[]},{type:"question",id:"Dka1Jk",label:"Recall the role of viral surface glycoproteins in determining host range.",children:[]},{type:"question",id:"lNavYO",label:"Recognize the characteristics of (+)ssRNA viruses, and recall the diseases they can cause.",children:[]},{type:"question",id:"MNaMbO",label:"Recall the effectiveness of ethanol as a virucidal agent, and recall the characteristics of herpes simplex virus.",children:[]},{type:"question",id:"GNaBcO",label:"Recall the characteristics of positive-sense single-stranded RNA viruses.",children:[]},{type:"question",id:"06aejl",label:"Recall microscopic characteristics of the rotavirus.",children:[]},{type:"question",id:"QBau0M",label:"Recognize COVID-19, and recall its viral entry receptor.",children:[]}]},{type:"article",id:"kf0mm2/On0Itg",label:"Introduction to geriatrics",children:[{type:"question",id:"YqanCl",label:"Recognize the risks of polypharmacy in the elderly, and recall the Beers criteria.",children:[]}]},{type:"article",id:"kf0mm2/In0Yug",label:"General bacteriology",children:[{type:"question",id:"lYav6Q",label:"Recall the concept of specialized transduction and its role in bacterial pathogenicity.",children:[]},{type:"question",id:"QeauAj",label:"Recognize septic shock due to Pseudomonas bacteremia, and recall the role of lipid A in hypotension.",children:[]},{type:"question",id:"dQaoE4",label:"Recall the relationship between peptidoglycan content and Gram staining results.",children:[]},{type:"question",id:"Xla9vk",label:"Recall the process of bacterial transformation.",children:[]},{type:"question",id:"M6aMll",label:"Recall the mechanism of bacterial conjugation for horizontal gene transfer.",children:[]}]},{type:"article",id:"kf0mm2/pL0LAg",label:"Pelvic inflammatory disease",children:[{type:"question",id:"5T0ir2",label:"Recognize pelvic inflammatory disease, and choose the most appropriate additional test for sexually transmitted infections.",children:[]}]},{type:"article",id:"kf0mm2/Wo0PaS",label:"Differences (disorders) of sex development",children:[{type:"question",id:"60ajSQ",label:"Recognize Turner syndrome with somatic mosaicism, and recall its genetic cause.",children:[]}]},{type:"article",id:"kf0mm2/jo0_bS",label:"Antiarrhythmic drugs",children:[{type:"question",id:"Hz0K8i",label:"Recall the effects of class IC antiarrhythmics on the cardiac action potential, and recall the role of voltage-gated sodium channels in phase 0.",children:[]}]},{type:"article",id:"kf0mm2/4o03XS",label:"Lipid disorders",children:[{type:"question",id:"TWa6kj",label:"Recognize hereditary abetalipoproteinemia, and choose the most appropriate dietary modification.",children:[]},{type:"question",id:"nsa7vN",label:"Choose the most appropriate screening for a middle-aged adult male with no additional ASCVD risk factors.",children:[]}]},{type:"article",id:"kf0mm2/Mo0McS",label:"The cell cycle",children:[{type:"question",id:"RTalqP",label:"Recall the mechanism of action of erlotinib, and recall the phases of the cell cycle.",children:[]},{type:"question",id:"GkaB6k",label:"Recall the function of Rb protein in cell cycle regulation, and recall the effect of CDK4 activation on Rb.",children:[]},{type:"question",id:"2paTKl",label:"Recall the role of cyclin B in cell cycle regulation.",children:[]},{type:"question",id:"Cpaq7l",label:"Recall the cell types most affected by chemotherapeutic agents targeting DNA replication.",children:[]}]},{type:"article",id:"kf0mm2/Lo0wcS",label:"The cell",children:[{type:"question",id:"deaoBj",label:"Recall the concept of facilitated diffusion, and recall its examples in different tissues.",children:[]},{type:"question",id:"s2atQP",label:"Recall the cellular structures stained by Nissl stain, and recall the distribution of rough endoplasmic reticulum in neurons.",children:[]},{type:"question",id:"6hajU4",label:"Recall the mechanism of action of colchicine, and recall the cellular processes dependent on microtubules.",children:[]},{type:"question",id:"YOanIk",label:"Recall the role of calcium ions in cell adhesion mediated by cadherins.",children:[]}]},{type:"article",id:"kf0mm2/oo001S",label:"Nucleotides, DNA, and RNA",children:[{type:"question",id:"sy0tgi",label:"Recall the composition of histones, and recall their interaction with DNA.",children:[]},{type:"question",id:"Gy0Bgi",label:"Recall the function of histone deacetylase, and recall its effect on DNA coiling.",children:[]}]},{type:"article",id:"kf0mm2/Ko0U1S",label:"DNA replication and repair",children:[{type:"question",id:"CB0q1i",label:"Recall the indications and mechanism of action of fluoroquinolones, and recall the process of bacterial DNA replication.",children:[]},{type:"question",id:"Ey08Si",label:"Recall the functions of DNA polymerase I in bacterial DNA replication.",children:[]},{type:"question",id:"vy0ASi",label:"Recognize xeroderma pigmentosum, and recall the role of excision endonuclease in DNA repair.",children:[]},{type:"question",id:"Dy01hi",label:"Recognize malignant melanoma, and recall the effects of UV radiation on DNA.",children:[]},{type:"question",id:"By0zhi",label:"Recognize xeroderma pigmentosum, and recall its clinical presentation.",children:[]},{type:"question",id:"wA0hNi",label:"Recall the function of telomerase in eukaryotic cells.",children:[]},{type:"question",id:"l_0voi",label:"Recall the characteristics of eukaryotic DNA replication origins.",children:[]},{type:"question",id:"6_0j6i",label:"Recall the initial step of base excision repair and the role of DNA glycosylase.",children:[]},{type:"question",id:"p_0L6i",label:"Recall the unique functions of DNA polymerase I in prokaryotic DNA replication.",children:[]},{type:"question",id:"J_0s6i",label:"Recall the role of primase in DNA replication.",children:[]},{type:"question",id:"f4akik",label:"Recall the primary mechanism of DNA repair for radiation-induced damage.",children:[]},{type:"question",id:"T4a6ik",label:"Recall the process of lagging strand synthesis in DNA replication.",children:[]},{type:"question",id:"b6aHjl",label:"Recall the function of DNA polymerase III in DNA replication.",children:[]},{type:"question",id:"m6aVll",label:"Recall the cellular effects of ionizing radiation on cancer cells.",children:[]}]},{type:"article",id:"kf0mm2/po0L1S",label:"Gene expression and transcription",children:[{type:"question",id:"6Vajvj",label:"Recall eukaryotic cell organelles, and the location of RNA polymerase I.",children:[]},{type:"question",id:"mlaVxk",label:"Recall the function of small nuclear ribonucleoproteins in mRNA processing.",children:[]},{type:"question",id:"plaLBk",label:"Recall the regulation of the lac operon by glucose and lactose, and recall the role of adenylate cyclase in cAMP production.",children:[]},{type:"question",id:"ulapAk",label:"Recall the process of alternative pre-mRNA splicing in eukaryotic cells.",children:[]}]},{type:"article",id:"kf0mm2/Jo0s1S",label:"Translation and protein synthesis",children:[{type:"question",id:"RA0lji",label:"Recognize diphtheria, and recall the mechanism of diphtheria toxin.",children:[]},{type:"question",id:"kYam6Q",label:"Recall the concept of degeneracy in the genetic code.",children:[]},{type:"question",id:"dcaoYj",label:"Recall the genetic code for amino acids, and recognize the clinical features of ataxia-telangiectasia.",children:[]},{type:"question",id:"N2a-3P",label:"Recall the steps of the elongation phase of protein synthesis.",children:[]},{type:"question",id:"d4aoRk",label:"Recall the concept of point mutations, and recall the mRNA stop codon sequences.",children:[]},{type:"question",id:"skat6k",label:"Recall the role of the AUG start codon in translation initiation.",children:[]},{type:"question",id:"ZlaZvk",label:"Recall the function of N-terminal peptidase, and recall the anticodon for the start codon in eukaryotic mRNA.",children:[]},{type:"question",id:"G5aBlO",label:"Recall the role of the rough endoplasmic reticulum in protein synthesis.",children:[]}]},{type:"article",id:"kf0mm2/qo0C1S",label:"Signal transduction",children:[{type:"question",id:"7A04Oi",label:"Recognize metoprolol toxicity, and recall its effect on adenylyl cyclase activity.",children:[]},{type:"question",id:"zWarLj",label:"Recognize severe hypoglycemia treatment, and recall the mechanism of action of glucagon.",children:[]},{type:"question",id:"MUaMdP",label:"Recall the treatment for anemia of chronic kidney disease, and recall the EPO receptor signaling pathway.",children:[]},{type:"question",id:"lTavIP",label:"Recall the mechanism of action of fenoldopam, and recall the intracellular signaling pathways of Gs protein-coupled receptors.",children:[]},{type:"question",id:"KTaU7P",label:"Recall the mechanism of action of tamsulosin, and recall the intracellular signaling pathways affected by alpha-1 receptor inhibition.",children:[]},{type:"question",id:"MKaMSl",label:"Recall the mechanism of action of desmopressin, and recall its effect on kidney principal cells.",children:[]}]},{type:"article",id:"kf0mm2/ro0fWS",label:"Connective tissue",children:[{type:"question",id:"TPa6Vk",label:"Recall the role of hydrogen and disulfide bonds in collagen synthesis.",children:[]},{type:"question",id:"WNaPZO",label:"Recall alpha-1 antitrypsin deficiency, and recall the properties of elastin.",children:[]},{type:"question",id:"wmah3O",label:"Recall the phases of wound healing, and recall the types of collagen involved.",children:[]}]},{type:"article",id:"kf0mm2/7o04WS",label:"Cartilage",children:[{type:"question",id:"KdaUIj",label:"Recall the role of perichondrium in cartilage regeneration.",children:[]}]},{type:"article",id:"kf0mm2/so0tWS",label:"Muscle tissue",children:[{type:"question",id:"Qhaud4",label:"Recall the role of troponin C in muscle contraction.",children:[]}]},{type:"article",id:"kf0mm2/uo0pdS",label:"Basics of embryology",children:[{type:"question",id:"PeaW_j",label:"Recall the events occurring during prophase I of meiosis.",children:[]},{type:"question",id:"hfacNP",label:"Recall the stages of meiosis, and recall the cause of nondisjunction in triple X syndrome.",children:[]},{type:"question",id:"QPauek",label:"Recognize alobar holoprosencephaly, and recall the associated protein family involved in its pathogenesis.",children:[]}]},{type:"article",id:"kf0mm2/vo0AdS",label:"Embryogenesis",children:[{type:"question",id:"7Ta4HP",label:"Recall the timeline of embryonic development, and recall the events occurring in week 3.",children:[]},{type:"question",id:"hSaczP",label:"Recognize cervical radiculopathy, and recall the embryologic origin of the nucleus pulposus.",children:[]},{type:"question",id:"Z3aZS4",label:"Recognize first branchial arch anomalies, and recall its derivatives.",children:[]}]},{type:"article",id:"kf0mm2/9o0NVS",label:"Resting potentials and action potentials",children:[{type:"question",id:"Nca-cj",label:"Recall the role of voltage-gated potassium channels in cardiac action potentials.",children:[]},{type:"question",id:"llavCk",label:"Recall the determinants of resting membrane potential, and recall the role of ion permeability and equilibrium potentials.",children:[]}]},{type:"article",id:"kf0mm2/Ao0ReS",label:"Vitamins",children:[{type:"question",id:"1ea2Bj",label:"Recall the role of pantothenic acid in enzyme function.",children:[]},{type:"question",id:"mUaVdP",label:"Recognize a deficiency of vitamin B6 (pyridoxine), and recall its function in catecholamine synthesis.",children:[]},{type:"question",id:"0haec4",label:"Recognize osteomalacia, and recall its association with vitamin D metabolism impairment.",children:[]},{type:"question",id:"J3asj4",label:"Recall the cofactor required for aminotransferase function.",children:[]},{type:"question",id:"66ajNl",label:"Recognize pellagra, and recall its associated amino acid deficiency.",children:[]}]},{type:"article",id:"kf0mm2/1K022S",label:"Innate immune system",children:[{type:"question",id:"IbaYEQ",label:"Recall the infections associated with neutropenia.",children:[]}]},{type:"article",id:"kf0mm2/WK0P2S",label:"The cerebral cortex, meninges, basal ganglia, and ventricular system",children:[{type:"question",id:"W3aPh4",label:"Recall the CSF flow through the ventricular system of the brain.",children:[]}]},{type:"article",id:"kf0mm2/dK0o2S",label:"Lysosomal storage diseases",children:[{type:"question",id:"peaL-j",label:"Recognize Hunter syndrome, and recall its behavioral manifestations.",children:[]}]},{type:"article",id:"kf0mm2/FK0gRS",label:"Amino acids",children:[{type:"question",id:"R0alfQ",label:"Recall the titration curve and net charge of basic amino acids at body pH.",children:[]},{type:"question",id:"eUaxXP",label:"Recall the role of glutamine in renal gluconeogenesis and ammoniagenesis, and recall its transport in the proximal convoluted tubule.",children:[]},{type:"question",id:"c3aah4",label:"Recall the function of N-acetylglutamate, and recall its role in the urea cycle.",children:[]},{type:"question",id:"kOamsk",label:"Recall the metabolic derivatives of histidine, and recall their physiological effects.",children:[]}]},{type:"article",id:"kf0mm2/8K0ORS",label:"Proteins and peptides",children:[{type:"question",id:"RcalXj",label:"Recall the mechanism of cancer cachexia and muscle atrophy.",children:[]},{type:"question",id:"GmaBSO",label:"Recall the process and purpose of ubiquitination in protein modification.",children:[]},{type:"question",id:"iMaJoO",label:"Recall the forces responsible for maintaining α-helix conformation in proteins.",children:[]}]},{type:"article",id:"kf0mm2/260T4S",label:"Pancreas",children:[{type:"question",id:"WeaPBj",label:"Recall the initial cellular response to glucose entry into pancreatic beta-cells.",children:[]}]},{type:"article",id:"kf0mm2/560ilS",label:"Autonomic nervous system",children:[{type:"question",id:"KMaUpO",label:"Recall the mechanism of action of phenoxybenzamine and epinephrine, and the effect of β2 agonism with α2 antagonism.",children:[]},{type:"question",id:"vMaAqO",label:"Recall the effects of alpha-1 adrenergic receptor stimulation, and recall the neurotransmitter involved in sympathetic pupillary dilation.",children:[]}]},{type:"article",id:"kf0mm2/M60MlS",label:"Gastrointestinal tract",children:[{type:"question",id:"ZJaZsl",label:"Choose the pharmacotherapy that inhibits gastrointestinal motility and causes splanchnic artery vasoconstriction.",children:[]}]},{type:"article",id:"kf0mm2/n607lS",label:"Enzymes and biocatalysis",children:[{type:"question",id:"PSaW-P",label:"Recall the effects of enzyme concentration on Vmax and Km.",children:[]},{type:"question",id:"CIaqUN",label:"Recognize anticholinergic toxicity, and recall the concept of reversible competitive inhibition.",children:[]}]},{type:"article",id:"kf0mm2/L60wlS",label:"Electron transport chain and oxidative phosphorylation",children:[{type:"question",id:"7ca4dj",label:"Recognize the metabolic pathway used during short, strenuous exercise, and recall the expected change in blood constituents post-exercise.",children:[]},{type:"question",id:"t4aXOk",label:"Recall the role of alanine in the glucose-alanine cycle.",children:[]}]},{type:"article",id:"kf0mm2/o600NS",label:"Citric acid cycle",children:[{type:"question",id:"dMaonO",label:"Recall the role of pantothenic acid in metabolism, and recall the enzymes that require coenzyme A in the citric acid cycle.",children:[]}]},{type:"article",id:"kf0mm2/t60X5S",label:"Glycogen metabolism",children:[{type:"question",id:"hTacqP",label:"Recall the regulation of glycogenolysis, and recall the role of phosphorylase kinase.",children:[]},{type:"question",id:"mTaVrP",label:"Recall the effect of glucagon receptor antagonists on hepatic enzyme activity.",children:[]}]},{type:"article",id:"kf0mm2/y60dnS",label:"Carbohydrates",children:[{type:"question",id:"9VaN9j",label:"Recall the role of insulin in glucose transport, and recall the cell types expressing GLUT-4.",children:[]},{type:"question",id:"h6ackl",label:"Recall the pathway of glucose to fructose conversion, and recall the tissues expressing the necessary enzymes.",children:[]}]},{type:"article",id:"kf0mm2/1p02oS",label:"Lipids and their metabolism",children:[{type:"question",id:"YganFP",label:"Recall the cellular metabolism of ketone bodies and the role of hepatocytes.",children:[]},{type:"question",id:"x3aEk4",label:"Recognize the effects of a healthy lifestyle on lipid profile, and recall the laboratory marker likely to be increased.",children:[]},{type:"question",id:"VMaGnO",label:"Recall the role of glycerol kinase in triglyceride synthesis.",children:[]},{type:"question",id:"Jqaszl",label:"Recall the role of pancrelipase in digestion, and recall the synthesis of essential fatty acids.",children:[]}]},{type:"article",id:"kf0mm2/gp0FKS",label:"Laboratory methods",children:[{type:"question",id:"bRaHl4",label:"Recall the purpose of a northern blot, and recall the type of nucleic acid it detects.",children:[]},{type:"question",id:"84aOOk",label:"Recall the laboratory technique used to identify DNA-binding proteins.",children:[]},{type:"question",id:"jna_GO",label:"Recall the components required for polymerase chain reaction testing.",children:[]},{type:"question",id:"26aT4l",label:"Recall the clinical uses of colchicine.",children:[]}]},{type:"article",id:"kf0mm2/hp0c6S",label:"Aging changes",children:[{type:"question",id:"oTa07P",label:"Recall the effects of aging on skin, and recall the role of elastin fiber assembly.",children:[]},{type:"question",id:"56aill",label:"Recognize physiologic changes in male sexual function due to aging.",children:[]}]},{type:"article",id:"kf0mm2/Qp0u6S",label:"Glycolysis and gluconeogenesis",children:[{type:"question",id:"BYazrQ",label:"Recognize cardiogenic shock, and recall the effects of hypoxia on cellular metabolism.",children:[]},{type:"question",id:"uTapsP",label:"Recall the extrahepatic sites of gluconeogenesis.",children:[]},{type:"question",id:"2laTwk",label:"Recall the hexose monophosphate shunt and its products.",children:[]},{type:"question",id:"1Ma2nO",label:"Recall the role of GTP in metabolism, and recall the gluconeogenesis pathway.",children:[]},{type:"question",id:"RMaloO",label:"Recall the regulation of hepatic gluconeogenesis, and recall the role of acetyl coenzyme A.",children:[]},{type:"question",id:"jMa_oO",label:"Recall the role of lactate in energy metabolism, and recall the enzyme requiring NAD+ as a cofactor in glycolysis.",children:[]}]},{type:"article",id:"kf0mm2/lp0vpS",label:"Nerve tissue, synapses, and neurotransmitters",children:[{type:"question",id:"iRaJ54",label:"Recognize multiple sclerosis, and recall the embryologic origin of oligodendrocytes.",children:[]}]},{type:"article",id:"kf0mm2/aq0QCS",label:"Local inflammatory responses",children:[{type:"question",id:"G0aBhQ",label:"Recall the pathophysiology of edema due to acute local inflammation.",children:[]}]},{type:"article",id:"kf0mm2/fI0kXh",label:"COVID-19 (coronavirus disease 2019)",children:[{type:"question",id:"4Ba3aM",label:"Recognize symptoms of COVID-19, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"nBa7YM",label:"Recognize the treatment for COVID-19 in hospitalized patients, and recall the mechanism of action of remdesivir.",children:[]}]},{type:"article",id:"kf0mm2/nr073h",label:"Dilated cardiomyopathy",children:[{type:"question",id:"D_01qi",label:"Recognize dilated cardiomyopathy due to cardiotoxic medications, and recall its echocardiographic findings.",children:[]}]},{type:"article",id:"kf0mm2/M70Mmh",label:"Gynecomastia",children:[{type:"question",id:"zx0r_R",label:"Recognize normal pubertal gynecomastia.",children:[]},{type:"question",id:"sGat0m",label:"Recognize pubertal gynecomastia, and choose the most appropriate management.",children:[]}]},{type:"article",id:"kf0mm2/u70pnh",label:"Sexuality and sexual medicine",children:[{type:"question",id:"U0ab2Q",label:"Recognize normal sexual behaviors in adolescents and reassure concerned parents accordingly.",children:[]}]},{type:"article",id:"kf0mm2/TH06ph",label:"Principles of cancer care",children:[{type:"question",id:"W_0PMi",label:"Recall the cytokines involved in cancer anorexia-cachexia syndrome.",children:[]}]},{type:"article",id:"kf0mm2/sG0t03",label:"Well-child visits",children:[{type:"question",id:"IJ0YvS",label:"Recognize delayed growth in a child.",children:[]},{type:"question",id:"8J0ODS",label:"Recognize delayed language development in an 18-month-old child, and choose the most appropriate evaluation.",children:[]},{type:"question",id:"_Da5S5",label:"Choose the most appropriate health maintenance recommendation for a child's physical safety during activities.",children:[]},{type:"question",id:"zCaru5",label:"Choose the most appropriate child safety recommendation for a 6-month-old during a well-child examination.",children:[]},{type:"question",id:"J9Ysor",label:"Choose the most appropriate evaluation in a child with macrocephaly.",children:[]}]},{type:"article",id:"kf0mm2/nF07i3",label:"Stimulant intoxication and withdrawal",children:[{type:"question",id:"M1aMhj",label:"Recall the synaptic effects of cocaine.",children:[]}]},{type:"article",id:"kf0mm2/KF0UQ3",label:"Toxic alcohol poisoning",children:[{type:"question",id:"J1as3j",label:"Recognize methanol poisoning, and recall the mechanism of its antidote.",children:[]}]},{type:"article",id:"kf0mm2/EF08P3",label:"Overview of fungal infections",children:[{type:"question",id:"IjaYbk",label:"Recognize blastomycosis in an immunocompromised patient.",children:[]},{type:"question",id:"oka0Kk",label:"Recognize coccidioidomycosis, and recall its histological hallmark.",children:[]},{type:"question",id:"Claq_k",label:"Recognize the clinical presentation of sporotrichosis, and recall the characteristics of fungal dimorphism.",children:[]}]},{type:"article",id:"kf0mm2/080eO3",label:"Intimate partner violence",children:[{type:"question",id:"Rval-m",label:"Choose the most appropriate next step in management for a new patient of reproductive age.",children:[]}]},{type:"article",id:"kf0mm2/N80-53",label:"Infant nutrition and breastfeeding",children:[{type:"question",id:"dJ0oGS",label:"Choose the most appropriate dietary recommendation for a 6-month-old infant.",children:[]}]}]},{type:"system",id:"L0/df0oO2",label:"Cardiovascular System",children:[{type:"article",id:"df0oO2/df0oO2",label:"Diphtheria",children:[{type:"question",id:"jB0_0i",label:"Recognize diphtheria and its complications, and choose the appropriate treatment to prevent cardiac involvement.",children:[]}]},{type:"article",id:"df0oO2/1T02p2",label:"Giant cell arteritis",children:[{type:"question",id:"uB0pci",label:"Recognize giant cell arteritis, and recall its vascular complications.",children:[]}]},{type:"article",id:"df0oO2/fT0kJ2",label:"Vasculitides",children:[{type:"question",id:"15a2QO",label:"Recognize Takayasu arteritis, and recall its histopathological features.",children:[]}]},{type:"article",id:"df0oO2/8T0Os2",label:"Hemostasis and bleeding disorders",children:[{type:"question",id:"GQaBx4",label:"Recognize fibrinolytic therapy in STEMI, and recall its mechanism of action.",children:[]}]},{type:"article",id:"df0oO2/cS0aA2",label:"Intestinal ischemia",children:[{type:"question",id:"-P0DhT",label:"Recognize acute mesenteric ischemia, and choose the most appropriate revascularization technique.",children:[]}]},{type:"article",id:"df0oO2/3S0Sz2",label:"Pancreatic cancer",children:[{type:"question",id:"AmaRRO",label:"Recognize migratory thrombophlebitis, and choose the most appropriate diagnostic study.",children:[]}]},{type:"article",id:"df0oO2/qS0C0f",label:"Hemochromatosis",children:[{type:"question",id:"6D0j2R",label:"Recognize hereditary hemochromatosis as the cause of heart failure, and choose the appropriate intervention to prevent its progression.",children:[]},{type:"question",id:"WKaP2l",label:"Recognize hemochromatosis, and recall its effects on the cardiac conduction system.",children:[]}]},{type:"article",id:"df0oO2/rS0faf",label:"Heart failure",children:[{type:"question",id:"1m02eg",label:"Recognize high-output heart failure.",children:[]},{type:"question",id:"-s0Dxh",label:"Recognize congestive heart failure, and recall the compensatory activation of the RAAS system.",children:[]},{type:"question",id:"OG0Izh",label:"Recognize arterial hypertension as a cause of congestive heart failure.",children:[]},{type:"question",id:"lG0vzh",label:"Recognize congestive heart failure, and recall its hemodynamic findings.",children:[]},{type:"question",id:"UE0bE3",label:"Recognize signs of congestive heart failure, and recall factors associated with increased mortality.",children:[]},{type:"question",id:"xw0EOR",label:"Recognize signs of congestive heart failure, and choose agents that improve long-term survival.",children:[]},{type:"question",id:"gC0FrR",label:"Recognize heart failure with preserved ejection fraction, and recall its underlying pathophysiology.",children:[]},{type:"question",id:"PC0WHR",label:"Recognize heart failure, and recall the diagnostic finding of elevated serum brain natriuretic peptide levels.",children:[]},{type:"question",id:"MC0MsR",label:"Recognize impaired relaxation of the right ventricle.",children:[]},{type:"question",id:"HB0KXi",label:"Recognize congestive heart failure, and recall the effects of RAAS activation on renal arterioles.",children:[]},{type:"question",id:"J-0syi",label:"Recognize congestive heart failure, and choose agents that improve long-term survival.",children:[]},{type:"question",id:"yZadVQ",label:"Recognize traumatic arteriovenous fistula, and recall its complications.",children:[]},{type:"question",id:"KUaUVP",label:"Recognize myocardial infarction, and recall its effects on pulmonary capillary pressure.",children:[]},{type:"question",id:"aMaQMO",label:"Recognize increased ventricular wall stiffness as a cause of diastolic dysfunction.",children:[]},{type:"question",id:"cnaaHO",label:"Recognize systolic heart failure, and recall its hemodynamic findings.",children:[]},{type:"question",id:"9EaNBm",label:"Recognize right ventricular failure.",children:[]}]},{type:"article",id:"df0oO2/HS0Kaf",label:"Sinus node dysfunction",children:[{type:"question",id:"XC09qR",label:"Recognize sick sinus syndrome, and recall its common etiology.",children:[]}]},{type:"article",id:"df0oO2/sS0taf",label:"Supraventricular premature beats",children:[{type:"question",id:"Lt0wV3",label:"Recognize atrial premature beats in an asymptomatic patient, and choose the most appropriate management.",children:[]},{type:"question",id:"ut0p23",label:"Recognize atrial premature beats (APBs), and choose the most appropriate lifestyle modification.",children:[]}]},{type:"article",id:"df0oO2/GS0Baf",label:"Atrial fibrillation",children:[{type:"question",id:"Yt0nX3",label:"Recognize new-onset atrial fibrillation, and choose the most appropriate initial diagnostic test.",children:[]},{type:"question",id:"Kt0Ue3",label:"Recognize atrial fibrillation, and choose the most appropriate site for ablation.",children:[]},{type:"question",id:"TB06Zi",label:"Choose the most appropriate anticoagulant therapy prior to elective cardioversion in atrial fibrillation.",children:[]},{type:"question",id:"7_04pi",label:"Recognize paroxysmal atrial fibrillation.",children:[]},{type:"question",id:"n5a7kO",label:"Recognize acute splenic infarction, and recall the diagnostic finding of the most likely underlying cardiac arrhythmia.",children:[]},{type:"question",id:"IFaYjm",label:"Recognize new-onset atrial fibrillation and its spontaneous conversion to sinus rhythm, and choose the most appropriate management.",children:[]},{type:"question",id:"2waTR5",label:"Recognize atrial flutter on ECG.",children:[]}]},{type:"article",id:"df0oO2/FS0gYf",label:"Supraventricular tachycardia",children:[{type:"question",id:"hS0cz2",label:"Recognize AV nodal reentrant tachycardia, and choose the most appropriate initial treatment.",children:[]},{type:"question",id:"mJ0VuS",label:"Recognize Wolff-Parkinson-White syndrome, and choose the appropriate antiarrhythmic therapy.",children:[]},{type:"question",id:"it0JW3",label:"Recognize Wolff-Parkinson-White syndrome, and recall its characteristic ECG findings.",children:[]},{type:"question",id:"kt0md3",label:"Choose the most appropriate pharmacotherapy for supraventricular tachycardia after vagal maneuvers fail.",children:[]},{type:"question",id:"Ot0Id3",label:"Recognize paroxysmal supraventricular tachycardia, and recall its most common cause.",children:[]},{type:"question",id:"aZaQZQ",label:"Recognize atrioventricular nodal re-entrant tachycardia, and recall the nerve involved in vagal maneuvers.",children:[]},{type:"question",id:"bZaHZQ",label:"Recognize Wolff-Parkinson-White syndrome, and recall its characteristic ECG findings.",children:[]},{type:"question",id:"05aeiO",label:"Recall the physiological changes that occur during the Valsalva maneuver.",children:[]}]},{type:"article",id:"df0oO2/8S0OYf",label:"Premature ventricular contractions",children:[{type:"question",id:"GS0Baf",label:"Recognize benign premature ventricular contractions, and choose the most appropriate initial management.",children:[]},{type:"question",id:"1N02Zg",label:"Recognize hypokalemia as a cause of postoperative arrhythmias.",children:[]}]},{type:"article",id:"df0oO2/uS0pYf",label:"Long QT syndrome",children:[{type:"question",id:"GJ0BvS",label:"Recognize long QT syndrome, and choose the most appropriate initial therapy.",children:[]},{type:"question",id:"d_0oMi",label:"Recognize Romano-Ward syndrome, and recall its genetic basis.",children:[]},{type:"question",id:"eZax0Q",label:"Recognize congenital long QT syndrome, and recall its associated clinical features.",children:[]},{type:"question",id:"KmaUgO",label:"Recognize Jervell and Lange-Nielsen syndrome, and recall its electrocardiogram findings.",children:[]}]},{type:"article",id:"df0oO2/ES08Yf",label:"Ventricular tachycardia",children:[{type:"question",id:"FS0gYf",label:"Recognize hemodynamically unstable ventricular tachycardia, and choose the most appropriate intervention.",children:[]},{type:"question",id:"DG01Y3",label:"Recognize polymorphic ventricular tachycardia (torsades de pointes), and choose the most appropriate initial treatment.",children:[]},{type:"question",id:"Su0yq3",label:"Recognize drug-induced prolonged QT interval as a cause of syncope.",children:[]},{type:"question",id:"tA0Xli",label:"Recognize torsade de pointes, and recall its association with prolonged QT interval.",children:[]},{type:"question",id:"Uuabqm",label:"Recognize sustained monomorphic ventricular tachycardia, and choose the appropriate pharmacologic treatment.",children:[]}]},{type:"article",id:"df0oO2/DS01bf",label:"Coronary artery disease",children:[{type:"question",id:"pF0LQ3",label:"Recognize vasospastic angina, and choose the first-line long-term treatment.",children:[]},{type:"question",id:"HF0Kj3",label:"Recognize stable coronary artery disease, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"GF0Bj3",label:"Recognize atypical chest pain suggestive of coronary heart disease, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"W80Pl3",label:"Recognize vasospastic angina, and recall its associated conditions.",children:[]},{type:"question",id:"d80ol3",label:"Recognize coronary steal syndrome, and recall its underlying mechanism.",children:[]},{type:"question",id:"TD06dR",label:"Choose medications and substances to discontinue prior to a cardiac exercise stress test.",children:[]},{type:"question",id:"cx0avR",label:"Recognize low pretest probability of coronary artery disease, and choose the most appropriate next step in evaluation.",children:[]},{type:"question",id:"CA0qNi",label:"Recognize vasospastic angina, and choose the most appropriate pharmacotherapy for prevention.",children:[]},{type:"question",id:"f_0kni",label:"Recall the concept of hibernating myocardium.",children:[]},{type:"question",id:"0ZaeZQ",label:"Recall the relationship between vessel radius and resistance to blood flow using Poiseuille's law.",children:[]},{type:"question",id:"NZa-bQ",label:"Recognize Prinzmetal angina, and recall its underlying mechanism.",children:[]},{type:"question",id:"LMaw6O",label:"Recall the effects of ranolazine on myocardial oxygen consumption and energy metabolism.",children:[]},{type:"question",id:"unapEO",label:"Recognize dipyridamole-induced coronary steal syndrome, and recall its mechanism.",children:[]},{type:"question",id:"zKarQl",label:"Recognize stable cardiac chest pain, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"QFau3m",label:"Choose the most appropriate pharmacotherapy to improve exercise tolerance in patients with stable angina.",children:[]}]},{type:"article",id:"df0oO2/wS0hbf",label:"Myocardial infarction",children:[{type:"question",id:"9F0N43",label:"Recognize atypical presentation of myocardial reinfarction, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"Ru0lI3",label:"Recognize Dressler syndrome.",children:[]},{type:"question",id:"lu0vr3",label:"Recognize acute pericarditis post-myocardial infarction, and choose the most appropriate treatment.",children:[]},{type:"question",id:"4E03D3",label:"Recognize Dressler syndrome (postmyocardial infarction syndrome).",children:[]},{type:"question",id:"F90g6R",label:"Recognize occlusion of the left anterior descending artery.",children:[]},{type:"question",id:"890O6R",label:"Choose the most appropriate additional pharmacotherapy for acute myocardial infarction.",children:[]},{type:"question",id:"u90p6R",label:"Recognize ventricular fibrillation as a cause of sudden cardiac death post-MI.",children:[]},{type:"question",id:"JC0sGR",label:"Recognize interventricular septum rupture.",children:[]},{type:"question",id:"-C0DuR",label:"Choose the appropriate long-term pharmacotherapy after percutaneous coronary intervention.",children:[]},{type:"question",id:"SA0yQi",label:"Recognize inferior wall myocardial infarction and its associated ECG changes, and recall the coronary artery anatomy.",children:[]},{type:"question",id:"b_0H5i",label:"Recognize acute pericarditis post-myocardial infarction, and recall the associated histopathological finding.",children:[]},{type:"question",id:"kz0mGi",label:"Recognize myocardial infarction, and recall its early complications.",children:[]},{type:"question",id:"bcaHaj",label:"Recognize rupture of the chordae tendinae post-myocardial infarction.",children:[]},{type:"question",id:"zjar1k",label:"Recognize occlusion of the posterior descending artery.",children:[]},{type:"question",id:"aPaQWk",label:"Recognize acute lateral wall myocardial infarction, and recall the coronary artery anatomy.",children:[]},{type:"question",id:"dPaodk",label:"Recognize complications of myocardial infarction, and recall the associated histopathological changes.",children:[]},{type:"question",id:"pmaLgO",label:"Recognize acute inferior myocardial infarction.",children:[]},{type:"question",id:"tmaXhO",label:"Recognize ST elevation myocardial infarction (STEMI), and recall the ECG leads corresponding to the LAD artery territory.",children:[]},{type:"question",id:"4Ma3KO",label:"Recognize unstable angina pectoris.",children:[]},{type:"question",id:"GsaBwN",label:"Recognize ventricular pseudoaneurysm as a cause of acute limb ischemia post-myocardial infarction.",children:[]},{type:"question",id:"JFasQm",label:"Recognize ventricular aneurysm as a late complication of myocardial infarction.",children:[]}]},{type:"article",id:"df0oO2/9S0Nbf",label:"Acute rheumatic fever",children:[{type:"question",id:"ZR0Zlf",label:"Recognize acute rheumatic fever with carditis, and choose the appropriate duration of secondary prophylaxis.",children:[]},{type:"question",id:"aR0Qlf",label:"Recognize acute rheumatic fever.",children:[]},{type:"question",id:"f5akjO",label:"Recognize Sydenham chorea, and recall its complications.",children:[]},{type:"question",id:"i5aJPO",label:"Recognize rheumatic heart disease, and recall its pathogenic mechanism.",children:[]},{type:"question",id:"r5aflO",label:"Recognize the link between bacterial pharyngitis and mitral valve disease, and choose the public health intervention to reduce its surgical treatment.",children:[]}]},{type:"article",id:"df0oO2/CS0qbf",label:"Infective endocarditis",children:[{type:"question",id:"4h03Vf",label:"Recognize infective endocarditis due to Streptococcus gallolyticus, and choose the most appropriate post-treatment investigation.",children:[]},{type:"question",id:"tQ0XBf",label:"Recognize the need for infective endocarditis prophylaxis in patients with prosthetic heart valves undergoing dental procedures, and choose the most appropriate antibiotic regimen.",children:[]},{type:"question",id:"FQ0gBf",label:"Recognize Staphylococcus epidermidis as a cause of prosthetic valve infective endocarditis.",children:[]},{type:"question",id:"uQ0pBf",label:"Choose the appropriate antibiotic regimen for prosthetic valve infective endocarditis due to methicillin-susceptible staphylococci.",children:[]},{type:"question",id:"EQ08Bf",label:"Recognize right-sided infective endocarditis, and recall its complications.",children:[]},{type:"question",id:"DQ01yf",label:"Recognize subacute infective endocarditis, and recall its common pathogens.",children:[]},{type:"question",id:"wQ0hyf",label:"Choose the most appropriate antibiotic therapy for infective endocarditis caused by HACEK organisms.",children:[]},{type:"question",id:"9Q0Nyf",label:"Recognize Staphylococcus aureus as a cause of acute infective endocarditis.",children:[]},{type:"question",id:"CQ0qyf",label:"Recognize infective endocarditis in children with congenital heart disease.",children:[]},{type:"question",id:"AQ0RAf",label:"Recognize acute infective endocarditis in an intravenous drug user, and choose the initial empiric antibiotic therapy.",children:[]},{type:"question",id:"-Q0DAf",label:"Recognize septic emboli from infective endocarditis.",children:[]},{type:"question",id:"Zj0Z_f",label:"Recognize acute infective endocarditis, and choose the initial diagnostic test.",children:[]},{type:"question",id:"0j0e_f",label:"Recognize infective endocarditis with complications, and recall the echocardiographic findings.",children:[]},{type:"question",id:"Yj0n_f",label:"Recognize acute infective endocarditis, and recall its common risk factors.",children:[]},{type:"question",id:"Mj0MaT",label:"Recognize Enterococcus faecalis infection as a cause of infective endocarditis.",children:[]},{type:"question",id:"yP0dhT",label:"Recognize infective endocarditis with acute aortic regurgitation and left-sided heart failure, and choose the most appropriate surgical intervention.",children:[]},{type:"question",id:"AA0Rmi",label:"Recognize acute infective endocarditis, and recall the histopathology of Janeway lesions.",children:[]},{type:"question",id:"zA0rmi",label:"Recognize Libman-Sacks endocarditis associated with systemic lupus erythematosus.",children:[]},{type:"question",id:"PVaWuj",label:"Recognize infective endocarditis, and recall the characteristics of Enterococcus faecalis.",children:[]},{type:"question",id:"RealAj",label:"Recognize infective endocarditis, and recall the characteristic blood culture findings.",children:[]},{type:"question",id:"ljav0k",label:"Recognize acute right-sided infective endocarditis, and recall its complications.",children:[]},{type:"question",id:"pjaLYk",label:"Recognize Streptococcus sanguinis as a cause of subacute infective endocarditis.",children:[]},{type:"question",id:"mmaVTO",label:"Recognize infectious endocarditis, and recall its characteristic microscopic nail lesion findings.",children:[]},{type:"question",id:"T5a6jO",label:"Recognize prosthetic valve endocarditis, and recall the characteristics of its common causal pathogens.",children:[]},{type:"question",id:"j5a_PO",label:"Recognize nonbacterial thrombotic endocarditis associated with malignancy.",children:[]},{type:"question",id:"85aONO",label:"Recognize colon cancer as a predisposing factor for Streptococcus gallolyticus endocarditis.",children:[]},{type:"question",id:"cMaanO",label:"Recognize subacute bacterial endocarditis, and recall the role of dextrans in its pathogenesis.",children:[]},{type:"question",id:"8oaOdl",label:"Recognize infective endocarditis, and recall its pathogenesis.",children:[]},{type:"question",id:"ZuaZpm",label:"Recognize Staphylococcus aureus as a cause of acute infective endocarditis.",children:[]}]},{type:"article",id:"df0oO2/xS0Ebf",label:"Myocarditis",children:[{type:"question",id:"WR0PNf",label:"Recognize Coxsackie virus infection as a cause of myocarditis.",children:[]},{type:"question",id:"dR0oNf",label:"Recognize dilated cardiomyopathy secondary to viral myocarditis.",children:[]},{type:"question",id:"hA0cji",label:"Recognize dilated cardiomyopathy secondary to viral myocarditis, and recall its laboratory findings.",children:[]},{type:"question",id:"sZat1Q",label:"Recognize viral myocarditis, and recall its common viral etiologies.",children:[]}]},{type:"article",id:"df0oO2/-S0DXf",label:"Valvular heart diseases",children:[{type:"question",id:"Jj0sYT",label:"Recognize valve degeneration as a cause of CHF symptoms post valve replacement.",children:[]},{type:"question",id:"Jz0sFi",label:"Recognize tricuspid regurgitation, and recall the effect of inspiration on right ventricular hemodynamics.",children:[]},{type:"question",id:"IPaYTk",label:"Recall the auscultatory findings of pulmonary valve stenosis.",children:[]},{type:"question",id:"XOa9Ik",label:"Recognize tricuspid valve endocarditis, and recall its strongest predisposing factor.",children:[]}]},{type:"article",id:"df0oO2/Zh0Zcf",label:"Aortic valve stenosis",children:[{type:"question",id:"lL0vBg",label:"Recognize calcification of the aortic valve as a cause of syncope.",children:[]},{type:"question",id:"bu0Hp3",label:"Recognize exertional syncope, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"rE0fC3",label:"Recognize aortic stenosis, and recall its effect on left ventricular oxygen demand.",children:[]},{type:"question",id:"7D04fR",label:"Recognize aortic valve stenosis.",children:[]},{type:"question",id:"H_0Kpi",label:"Recognize aortic stenosis.",children:[]},{type:"question",id:"VZaG0Q",label:"Recognize aortic stenosis, and recall its murmur's timing relative to left ventricular pressure-volume changes during the cardiac cycle.",children:[]},{type:"question",id:"nha7e4",label:"Recognize aortic stenosis, and recall its effect on left ventricular oxygen demand.",children:[]},{type:"question",id:"b5aHiO",label:"Recognize dystrophic calcification on the aortic valve as a cause of aortic stenosis.",children:[]},{type:"question",id:"m5aVkO",label:"Recognize aortic stenosis, and recall its common etiologies.",children:[]},{type:"question",id:"rLaf_O",label:"Recall the cardiac pressure changes caused by aortic stenosis and the timing of its murmur during the cardiac cycle.",children:[]},{type:"question",id:"YBYnzr",label:"Recognize aortic stenosis, and recall its prognostic factors.",children:[]}]},{type:"article",id:"df0oO2/0h0ecf",label:"Aortic regurgitation",children:[{type:"question",id:"e60xPS",label:"Recognize Marfan syndrome with aortic regurgitation, and recall its classic cardiovascular examination finding.",children:[]},{type:"question",id:"fu0kq3",label:"Recognize aortic valve regurgitation.",children:[]},{type:"question",id:"Qu0uI3",label:"Recognize aortic regurgitation, and recall its most common cause in young adults in high-income countries.",children:[]},{type:"question",id:"Qw0uiR",label:"Recognize aortic valve regurgitation.",children:[]},{type:"question",id:"OA0IPi",label:"Recognize chronic aortic regurgitation, and recall its classic physical examination finding.",children:[]},{type:"question",id:"3z0Ssi",label:"Recognize aortic regurgitation in infective endocarditis.",children:[]},{type:"question",id:"CeaqaP",label:"Recognize aortic regurgitation, and recall its effect on left ventricular end-diastolic volume.",children:[]},{type:"question",id:"ILaY_O",label:"Recognize aortic regurgitation.",children:[]}]},{type:"article",id:"df0oO2/Yh0ncf",label:"Mitral regurgitation",children:[{type:"question",id:"z80r63",label:"Recognize chronic mitral valve regurgitation, and recall its associated findings.",children:[]},{type:"question",id:"Pu0Wr3",label:"Recognize papillary muscle rupture.",children:[]},{type:"question",id:"HD0KfR",label:"Recognize mitral valve regurgitation.",children:[]},{type:"question",id:"pbaLuQ",label:"Recognize mitral regurgitation, and recall its echocardiographic findings.",children:[]},{type:"question",id:"L5awkO",label:"Recognize mitral regurgitation, and recall the effect of systemic vascular resistance on regurgitant flow.",children:[]},{type:"question",id:"eMaxnO",label:"Recognize mitral annular dilation in peripartum cardiomyopathy.",children:[]},{type:"question",id:"uMapqO",label:"Recognize mitral regurgitation, and recall the association of an S3 heart sound with its exacerbation.",children:[]},{type:"question",id:"7La4_O",label:"Recognize mitral regurgitation, and recall its characteristic murmur.",children:[]}]},{type:"article",id:"df0oO2/Xh09cf",label:"Hypertension",children:[{type:"question",id:"gG0FAh",label:"Recognize hypertensive nephrosclerosis, and recall its pathological features.",children:[]},{type:"question",id:"Vv0G_3",label:"Choose an antihypertensive medication that also provides migraine prophylaxis.",children:[]},{type:"question",id:"Tv06z3",label:"Recognize decreased arterial compliance as a cause of isolated systolic hypertension.",children:[]},{type:"question",id:"gv0Fz3",label:"Recognize uncontrolled hypertension, and choose the most appropriate lifestyle modification.",children:[]},{type:"question",id:"iv0J-3",label:"Choose the most appropriate next step in the evaluation of newly diagnosed hypertension.",children:[]},{type:"question",id:"5laixk",label:"Choose the most appropriate initial pharmacotherapy for hypertension in African American patients.",children:[]},{type:"question",id:"x5aEmO",label:"Recall the causes of isolated systolic hypertension in the elderly.",children:[]},{type:"question",id:"HraKiN",label:"Choose the most appropriate next step after a single visit with elevated blood pressure readings.",children:[]},{type:"question",id:"iFaJ3m",label:"Choose the most effective lifestyle modification to lower blood pressure in patients with hypertension.",children:[]},{type:"question",id:"1Ca2I5",label:"Recall the causes of primary hypertension.",children:[]},{type:"question",id:"9xaNA5",label:"Recognize the need to differentiate between white coat hypertension and true hypertension, and choose the appropriate diagnostic method.",children:[]}]},{type:"article",id:"df0oO2/ch0a1f",label:"Peripheral arterial disease",children:[{type:"question",id:"j40_QT",label:"Recognize peripheral arterial disease, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"Mk0MoT",label:"Recognize Leriche syndrome, and recall its associated physical findings.",children:[]},{type:"question",id:"1O02rT",label:"Recognize moderate peripheral arterial disease, and choose the best initial management step.",children:[]},{type:"question",id:"V80Gl3",label:"Recognize peripheral arterial disease with claudication, and choose the next step after conservative measures fail.",children:[]},{type:"question",id:"o800n3",label:"Recognize peripheral arterial disease, and choose the appropriate pharmacotherapy.",children:[]},{type:"question",id:"ru0fs3",label:"Recognize peripheral arterial disease (PAD), and recall its cardiovascular complications.",children:[]},{type:"question",id:"cE0au3",label:"Recognize femoropopliteal artery stenosis.",children:[]},{type:"question",id:"d5aoQO",label:"Recognize peripheral arterial disease, and choose the pharmacotherapy that improves symptoms of intermittent claudication.",children:[]},{type:"question",id:"V5aGQO",label:"Recognize peripheral arterial disease (PAD) as the cause of claudication.",children:[]},{type:"question",id:"uFapPm",label:"Recognize critical limb ischemia in the context of peripheral artery disease, and choose the most appropriate intervention.",children:[]}]},{type:"article",id:"df0oO2/1h021f",label:"Acute limb ischemia",children:[{type:"question",id:"Uk0bMT",label:"Recognize acute limb ischemia, and choose the most appropriate next step in management.",children:[]},{type:"question",id:"RO0lHT",label:"Recognize acute limb ischemia, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"ct0ac3",label:"Recognize acute limb ischemia, and recall the prevention of thromboembolic events in atrial fibrillation.",children:[]},{type:"question",id:"uu0pG3",label:"Recognize acute limb ischemia, and recall the diagnostic study to identify its common underlying cause.",children:[]},{type:"question",id:"wu0ht3",label:"Recognize arterial embolism as a cause of acute limb ischemia.",children:[]},{type:"question",id:"fD0kdR",label:"Recognize drug-induced vasoconstriction.",children:[]},{type:"question",id:"Dpa17l",label:"Recognize arterial embolism as a cause of acute limb ischemia.",children:[]}]},{type:"article",id:"df0oO2/Wh0P1f",label:"Aneurysm",children:[{type:"question",id:"sk0t6T",label:"Recognize femoral artery pseudoaneurysm.",children:[]},{type:"question",id:"Ek08pT",label:"Recognize femoral artery pseudoaneurysm, and choose the most appropriate next step in management.",children:[]},{type:"question",id:"3u0SI3",label:"Recognize a femoral artery aneurysm.",children:[]}]},{type:"article",id:"df0oO2/dh0o1f",label:"Thoracic aortic aneurysm",children:[{type:"question",id:"8D0OTR",label:"Recognize the signs of a thoracic aortic aneurysm on imaging, and choose the most appropriate diagnostic test for confirmation.",children:[]},{type:"question",id:"yD0dSR",label:"Recognize cystic medial necrosis as a cause of thoracic aortic aneurysm.",children:[]},{type:"question",id:"1La29O",label:"Recognize cystic medial degeneration associated with Marfan syndrome.",children:[]}]},{type:"article",id:"df0oO2/2h0TWf",label:"Thromboangiitis obliterans",children:[{type:"question",id:"NF0-R3",label:"Recognize thromboangiitis obliterans, and choose the primary intervention to decrease the risk of amputation.",children:[]},{type:"question",id:"W5aPQO",label:"Recognize thromboangiitis obliterans, and recall its histologic findings.",children:[]}]},{type:"article",id:"df0oO2/fh0kWf",label:"Deep vein thrombosis",children:[{type:"question",id:"Ik0Y6T",label:"Recognize deep vein thrombosis in a postoperative patient, and choose the most appropriate next step in treatment.",children:[]},{type:"question",id:"Fk0gpT",label:"Recognize the high probability of deep vein thrombosis post-surgery, and choose the appropriate diagnostic test.",children:[]},{type:"question",id:"Kq0UzS",label:"Recognize postpartum deep venous thrombosis, and choose the most appropriate initial management.",children:[]},{type:"question",id:"Jw0sPR",label:"Recognize deep venous thrombosis, and choose the most appropriate additional screening test.",children:[]},{type:"question",id:"MlaMxk",label:"Recognize superficial thrombophlebitis.",children:[]},{type:"question",id:"Rmal2O",label:"Recognize deep vein thrombosis, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"-GaDbm",label:"Recognize superficial thrombophlebitis in a pregnant patient, and choose the most appropriate diagnostic test.",children:[]},{type:"question",id:"Fvagb5",label:"Recognize catheter-related thrombosis.",children:[]}]},{type:"article",id:"df0oO2/gh0FWf",label:"Chronic venous disease",children:[{type:"question",id:"i40JQT",label:"Recognize venous insufficiency as a cause of lower extremity ulcers.",children:[]},{type:"question",id:"qk0CKT",label:"Recognize chronic venous disease, and choose the most appropriate diagnostic test.",children:[]},{type:"question",id:"mF0Vi3",label:"Recognize chronic venous insufficiency, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"fx0kDR",label:"Recognize stasis dermatitis, and recall its pathophysiology.",children:[]},{type:"question",id:"oXa0_Q",label:"Recognize chronic venous insufficiency, and recall its pathophysiology.",children:[]},{type:"question",id:"CKaqil",label:"Recognize chronic venous disease, and recall the direction of blood flow that confirms the diagnosis.",children:[]},{type:"question",id:"BKazil",label:"Recognize varicose veins, and recall the diagnostic imaging findings.",children:[]},{type:"question",id:"Y-anDM",label:"Recognize postthrombotic syndrome as a cause of venous insufficiency.",children:[]}]},{type:"article",id:"df0oO2/Lh0wef",label:"Obstructive sleep apnea",children:[{type:"question",id:"Js0sDh",label:"Recognize symptoms of obstructive sleep apnea, and recall its effect on blood pressure.",children:[]},{type:"question",id:"74a4kk",label:"Recognize obstructive sleep apnea as a cause of secondary hypertension.",children:[]}]},{type:"article",id:"df0oO2/oh00Uf",label:"Pulmonary embolism",children:[{type:"question",id:"uk0ppT",label:"Recognize the high clinical probability of pulmonary embolism, and choose the most appropriate initial step in management.",children:[]},{type:"question",id:"Nw0-QR",label:"Recognize the iliac vein as the common origin of pulmonary emboli.",children:[]}]},{type:"article",id:"df0oO2/uh0pff",label:"Pericardial effusion and cardiac tamponade",children:[{type:"question",id:"eh0x1f",label:"Recognize cardiac 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recall its diagnostic finding.",children:[]},{type:"question",id:"k6amOl",label:"Recognize cardiac tamponade.",children:[]}]},{type:"article",id:"df0oO2/_h05gf",label:"Carcinoid tumor",children:[{type:"question",id:"93aNk4",label:"Recognize carcinoid syndrome with hepatic metastasis.",children:[]}]},{type:"article",id:"df0oO2/c30ahf",label:"Hemorrhoids",children:[{type:"question",id:"eWax4j",label:"Recognize external hemorrhoids, and recall their blood supply.",children:[]}]},{type:"article",id:"df0oO2/UR0bmf",label:"Overview of stroke",children:[{type:"question",id:"Uo0bYS",label:"Recognize stroke symptoms, and recall the strongest predisposing factor for stroke.",children:[]}]},{type:"article",id:"df0oO2/3R0S5f",label:"Fibromuscular dysplasia",children:[{type:"question",id:"DJ01wS",label:"Recognize fibromuscular dysplasia in a hypertensive emergency, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"9naNvO",label:"Recognize fibromuscular dysplasia, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"r6afml",label:"Recognize fibromuscular dysplasia.",children:[]}]},{type:"article",id:"df0oO2/aj0Q_f",label:"Preoperative management",children:[{type:"question",id:"tP0XgT",label:"Recognize the need for preoperative cardiac risk assessment, and choose the most appropriate stress test.",children:[]}]},{type:"article",id:"df0oO2/Hj0KbT",label:"Epistaxis",children:[{type:"question",id:"2_0Tni",label:"Recognize hereditary hemorrhagic telangiectasia, and recall its cardiac complications.",children:[]}]},{type:"article",id:"df0oO2/VP0GdT",label:"Cellular changes and adaptive responses",children:[{type:"question",id:"O5aI4O",label:"Recognize lipofuscin granules, and recall their composition.",children:[]}]},{type:"article",id:"df0oO2/PP0WUT",label:"Major depressive disorder",children:[{type:"question",id:"WCaPI5",label:"Recognize depression post-myocardial infarction as a factor affecting prognosis.",children:[]}]},{type:"article",id:"df0oO2/Z40Z3T",label:"Environmental pathology",children:[{type:"question",id:"mA0V4i",label:"Recognize a lightning strike.",children:[]}]},{type:"article",id:"df0oO2/U40biT",label:"Down syndrome",children:[{type:"question",id:"Co0qVS",label:"Recognize Down syndrome, and recall its associated cardiac anomalies.",children:[]},{type:"question",id:"tbaXvQ",label:"Recognize atrioventricular septal defect associated with Down syndrome.",children:[]}]},{type:"article",id:"df0oO2/4403jT",label:"Acyanotic congenital heart defects",children:[{type:"question",id:"H50Klg",label:"Recognize an atrial septal defect.",children:[]},{type:"question",id:"eM0xng",label:"",children:[]},{type:"question",id:"8o0OdS",label:"Recognize a large ventricular septal defect, and recall the changes in pulmonary vascular resistance postnatally.",children:[]},{type:"question",id:"uo0pdS",label:"Recognize a ventricular septal defect, and recall its pathophysiology.",children:[]},{type:"question",id:"xo0EVS",label:"Recognize a small ventricular septal defect, and choose the most appropriate management for an asymptomatic patient.",children:[]},{type:"question",id:"yo0deS",label:"Recognize patent foramen ovale (PFO) in an asymptomatic patient, and choose the most appropriate management.",children:[]},{type:"question",id:"aK0QUS",label:"Recognize ventricular septal defect (VSD), and recall its long-term complications.",children:[]},{type:"question",id:"wB0h1i",label:"Recognize symptomatic ventricular septal defect (VSD), and recall the maneuvers that affect its murmur.",children:[]},{type:"question",id:"nA074i",label:"Recognize aortic coarctation, and recall its complications.",children:[]},{type:"question",id:"sA0tOi",label:"Recognize the clinical features of a large patent ductus arteriosus, and recall the expected echocardiographic finding.",children:[]},{type:"question",id:"Z_0Z5i",label:"Recognize coarctation of the aorta, and recall its diagnostic findings.",children:[]},{type:"question",id:"Mz0Mti",label:"Recognize paradoxical embolism, and recall the diagnostic finding of the most common cardiac anomaly associated with it.",children:[]},{type:"question",id:"pz0LFi",label:"Recognize atrial septal defect, and recall its complications.",children:[]},{type:"question",id:"2-0T9i",label:"Recognize ventricular septal defect (VSD), and recall its long-term complications.",children:[]},{type:"question",id:"JWasmj",label:"Recall the cardiac pressure changes that would occur after successful repair of a ventricular septal defect.",children:[]},{type:"question",id:"3maS2O",label:"Recall the cardiac catheterization findings of a ventricular septal defect.",children:[]},{type:"question",id:"6majgO",label:"Recall the consequences of abnormal endocardial cushion development.",children:[]},{type:"question",id:"v5aANO",label:"Recognize Eisenmenger syndrome, and recall its cardiac complications.",children:[]},{type:"question",id:"A5aR5O",label:"Recognize patent ductus arteriosus.",children:[]},{type:"question",id:"_5a55O",label:"Recognize a ventricular septal defect.",children:[]},{type:"question",id:"Xna97O",label:"Recognize a ventricular septal defect (VSD), and recall its effects on the pulmonary vasculature.",children:[]},{type:"question",id:"u7apnN",label:"Recognize aortic coarctation, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"dHao6N",label:"Recognize coarctation of the aorta, and recall its clinical features.",children:[]},{type:"question",id:"WGaPyN",label:"Recognize patent ductus arteriosus.",children:[]},{type:"question",id:"dGaoyN",label:"Recognize a ventricular septal defect.",children:[]},{type:"question",id:"rCaft5",label:"Recognize paradoxical embolism, and choose the most appropriate diagnostic study.",children:[]}]},{type:"article",id:"df0oO2/K40U4T",label:"Esophageal atresia",children:[{type:"question",id:"2M0TLg",label:"Recognize a vascular ring causing respiratory symptoms in an infant, and choose the most appropriate next step in management.",children:[]}]},{type:"article",id:"df0oO2/2k0TMT",label:"Angioedema",children:[{type:"question",id:"9J0NwS",label:"Recognize hereditary angioedema, and recall its underlying cause.",children:[]}]},{type:"article",id:"df0oO2/hk0cnT",label:"Ehlers-Danlos syndrome and Marfan syndrome",children:[{type:"question",id:"mz0Vti",label:"Recognize Marfan syndrome, and recall its skeletal features.",children:[]},{type:"question",id:"35aSPO",label:"Recognize Marfan syndrome, and recall its cardiovascular complications.",children:[]}]},{type:"article",id:"df0oO2/sk0t6T",label:"Syphilis",children:[{type:"question",id:"Zz0Zri",label:"Recognize tertiary syphilis, and recall its cardiovascular complications.",children:[]}]},{type:"article",id:"df0oO2/kO0msT",label:"Shock",children:[{type:"question",id:"VS0GA2",label:"Recognize septic shock, and recall its hemodynamic findings.",children:[]},{type:"question",id:"D401lT",label:"Recognize features of shock, and recall the diagnostic finding of obstructive shock due to pulmonary embolism.",children:[]},{type:"question",id:"LC0wsR",label:"Recognize cardiogenic shock due to acute myocardial infarction.",children:[]},{type:"question",id:"c0aaUQ",label:"Recognize cardiogenic shock, and recall its effect on mental status.",children:[]},{type:"question",id:"SaayPQ",label:"Recognize septic shock, and recall its hemodynamic findings.",children:[]},{type:"question",id:"Ccaqej",label:"Recognize early hypovolemic shock, and recall the compensatory mechanisms maintaining blood pressure.",children:[]},{type:"question",id:"eKax2l",label:"Recognize hemorrhagic shock, and recall its first compensatory mechanism.",children:[]}]},{type:"article",id:"df0oO2/rl0fyT",label:"Cardiac catheterization",children:[{type:"question",id:"Sm0yUg",label:"Recognize retroperitoneal bleeding after a vascular procedure, and choose the most appropriate diagnostic test.",children:[]}]},{type:"article",id:"df0oO2/4N03Yg",label:"Management of trauma patients",children:[{type:"question",id:"VKaG2l",label:"Choose the most appropriate next step in managing hemorrhagic shock when intravenous access is not possible.",children:[]},{type:"question",id:"HHaK7N",label:"Choose the most appropriate next step in the management of hypovolemic shock due to internal hemorrhage.",children:[]}]},{type:"article",id:"df0oO2/kN0mYg",label:"Cardiac arrest and cardiopulmonary resuscitation",children:[{type:"question",id:"sS0taf",label:"Recognize pulseless electrical activity (PEA) arrest, and choose the most appropriate medication in cardiac arrest management.",children:[]},{type:"question",id:"oF00Q3",label:"Choose the appropriate pharmacotherapy for refractory ventricular fibrillation after defibrillation and epinephrine administration.",children:[]},{type:"question",id:"KF0UQ3",label:"Recognize ventricular fibrillation in the context of STEMI, and choose the most appropriate next step in management.",children:[]},{type:"question",id:"FC0gFR",label:"Recognize pulseless electrical activity (PEA), and choose the most appropriate initial resuscitative measure.",children:[]}]},{type:"article",id:"df0oO2/7N04cg",label:"Fundamentals of pharmacology",children:[{type:"question",id:"Ez08ui",label:"Recall the concept of tachyphylaxis, and recall its pharmacological mechanisms.",children:[]},{type:"question",id:"3laS9k",label:"Recall the effects of partial agonists on receptor activity.",children:[]},{type:"question",id:"zIar2N",label:"Recall the effects of phenoxybenzamine and norepinephrine on adrenergic receptors, and the pharmacodynamic interaction between an agonist and a noncompetitive antagonist.",children:[]}]},{type:"article",id:"df0oO2/tN0X1g",label:"Sympathomimetic drugs",children:[{type:"question",id:"Sy0yei",label:"Recall the mechanism of action of dobutamine.",children:[]}]},{type:"article",id:"df0oO2/8N0O1g",label:"Sympatholytic drugs",children:[{type:"question",id:"9MaNIO",label:"Choose the most appropriate pharmacotherapy to treat vasopressor extravasation.",children:[]}]},{type:"article",id:"df0oO2/uN0p1g",label:"Beta blockers",children:[{type:"question",id:"8_0OJi",label:"Recall the effects of beta blockers on the heart.",children:[]},{type:"question",id:"lZavbQ",label:"Recall the effects of beta-1 adrenergic receptor blockade on cardiac function.",children:[]},{type:"question",id:"LQaw94",label:"Recall the pharmacological effects of nonselective beta blockers with additional α-blocking action.",children:[]},{type:"question",id:"JmasgO",label:"Recognize the systemic side effects of ophthalmic beta blockers.",children:[]}]},{type:"article",id:"df0oO2/wN0hWg",label:"Local anesthetic agents",children:[{type:"question",id:"kUamWP",label:"Recognize local anesthetic systemic toxicity, and recall its mechanism of action.",children:[]}]},{type:"article",id:"df0oO2/am0QVg",label:"Statins",children:[{type:"question",id:"b80HO3",label:"Choose the first-line pharmacotherapy for dyslipidemia.",children:[]},{type:"question",id:"i80Jm3",label:"Recall the common adverse effects of statin therapy.",children:[]},{type:"question",id:"N80-53",label:"Choose the most appropriate management for statin-associated myopathy.",children:[]},{type:"question",id:"t0aX3Q",label:"Recognize the adverse effects of statins on muscle tissue.",children:[]},{type:"question",id:"inaJGO",label:"Choose the first-line pharmacotherapy for hyperlipidemia.",children:[]}]},{type:"article",id:"df0oO2/Ym0nVg",label:"Second-line lipid-lowering agents",children:[{type:"question",id:"M80MM3",label:"Recognize niacin-induced cutaneous flushing, and choose the most appropriate management to prevent this side effect.",children:[]},{type:"question",id:"r0afhQ",label:"Recall the effects of fibrates on lipid metabolism, and recall their associated risks.",children:[]},{type:"question",id:"D2a1PP",label:"Recall the effect of bile acid sequestrants on the lipid profile.",children:[]},{type:"question",id:"X5a9iO",label:"Recognize the side effects of niacin therapy, and choose the appropriate premedication to reduce these effects.",children:[]},{type:"question",id:"P6aWOl",label:"Recall the adverse effects of cholesterol absorption inhibitors.",children:[]}]},{type:"article",id:"df0oO2/Xm09Vg",label:"Amiodarone",children:[{type:"question",id:"Qv0u-3",label:"Recall the adverse effects associated with long-term use of amiodarone.",children:[]},{type:"question",id:"eYaxLQ",label:"Recognize the clinical features of pulmonary fibrosis, and recall adverse effects of antiarrhythmic drugs.",children:[]},{type:"question",id:"ggaFuP",label:"Recall the common adverse effects of amiodarone.",children:[]}]},{type:"article",id:"df0oO2/cm0aeg",label:"Calcium channel blockers",children:[{type:"question",id:"FE0gx3",label:"Recognize the side effects of calcium channel blockers in the treatment of hypertension.",children:[]},{type:"question",id:"uE0px3",label:"Choose the appropriate medication to prevent dihydropyridine calcium channel blocker-related peripheral edema.",children:[]},{type:"question",id:"B-0zzi",label:"Recall the cardiovascular effects of nondihydropyridine calcium channel blockers.",children:[]},{type:"question",id:"Z5aZiO",label:"Recall the adverse effects of non-dihydropyridine calcium channel blockers.",children:[]},{type:"question",id:"P5aW4O",label:"Recognize the side effects of antihypertensive medications.",children:[]}]},{type:"article",id:"df0oO2/1m02eg",label:"Renin-angiotensin-aldosterone system inhibitors",children:[{type:"question",id:"Nv0-ZR",label:"Recognize the benefits of ACE inhibitors in preventing cardiac remodeling post-myocardial infarction.",children:[]},{type:"question",id:"nma7TO",label:"Recognize ACE inhibitor-induced cough, and choose the appropriate alternative antihypertensive medication.",children:[]},{type:"question",id:"a5aQiO",label:"Recall the mechanism of action of neprilysin inhibitors.",children:[]}]},{type:"article",id:"df0oO2/Wm0Peg",label:"Nitrates",children:[{type:"question",id:"wD0hgR",label:"Recognize angina pectoris, and recall the mechanism of nitroglycerin.",children:[]},{type:"question",id:"Wz0P7i",label:"Recall the common adverse effects of nitrates.",children:[]},{type:"question",id:"fz0kHi",label:"Recall the effects of high-dose nitrate administration on the cardiovascular system.",children:[]},{type:"question",id:"Sz0yHi",label:"Recognize nitrate tolerance in stable angina, and choose the appropriate modification for pharmacotherapy.",children:[]},{type:"question",id:"5-0iBi",label:"Recall the effect of nitroglycerin on myocardial preload and end-diastolic pressure.",children:[]}]},{type:"article",id:"df0oO2/Vm0Geg",label:"Cardiac glycosides",children:[{type:"question",id:"Lu0w73",label:"Recognize digoxin toxicity, and recall its mechanism of action.",children:[]},{type:"question",id:"WE0Pu3",label:"Recognize digoxin intoxication, and recall its associated electrolyte abnormality.",children:[]},{type:"question",id:"WMaPnO",label:"Recall the effects of digoxin on cardiac conduction and vagal tone.",children:[]}]},{type:"article",id:"df0oO2/em0xeg",label:"Phosphodiesterase inhibitors",children:[{type:"question",id:"kE0mD3",label:"Recognize drug-induced hypotension, and recall the role of cGMP in vasodilation.",children:[]},{type:"question",id:"V_0GMi",label:"Recall the mechanism of action of phosphodiesterase type 5 inhibitors.",children:[]},{type:"question",id:"25aTjO",label:"Recall the adverse effects of phosphodiesterase type 3 inhibitors.",children:[]}]},{type:"article",id:"df0oO2/Um0bUg",label:"Antiplatelet agents",children:[{type:"question",id:"T-069i",label:"Recognize Samter's triad, and choose an alternative antiplatelet agent for aspirin allergy.",children:[]},{type:"question",id:"RQalD4",label:"Recognize drug-induced neutropenia, and recall the side effects of antiplatelet medications.",children:[]},{type:"question",id:"QJauFl",label:"Recall the role of thromboxane A2 in platelet aggregation and thrombosis.",children:[]}]},{type:"article",id:"df0oO2/Tm06Ug",label:"Oral anticoagulants",children:[{type:"question",id:"lQavw4",label:"Recognize atrial fibrillation, and recall the mechanism of action for long-term stroke prevention.",children:[]}]},{type:"article",id:"df0oO2/gm0FUg",label:"Diuretics",children:[{type:"question",id:"OdaIJj",label:"Recognize first-dose hypotension with ACE inhibitors, and recall the synergistic effect of thiazide diuretics.",children:[]}]},{type:"article",id:"df0oO2/4m03fg",label:"Chemotherapeutic agents",children:[{type:"question",id:"Ex08yR",label:"Recognize the treatment for acute myeloid leukemia, and recall the long-term complications of anthracycline chemotherapy.",children:[]}]},{type:"article",id:"df0oO2/7m04Sg",label:"Antidiabetic drugs",children:[{type:"question",id:"EE08x3",label:"Recognize acute decompensated heart failure with renal insufficiency, and choose the most appropriate medication adjustment.",children:[]},{type:"question",id:"pTaL7P",label:"Choose modifications for pharmacotherapy in patients with acute kidney injury and heart failure.",children:[]}]},{type:"article",id:"df0oO2/b50Hig",label:"Syncope",children:[{type:"question",id:"ko0mXS",label:"Recognize carotid sinus hypersensitivity.",children:[]},{type:"question",id:"HUaKeP",label:"Recognize orthostatic hypotension, and recall its pathophysiology.",children:[]}]},{type:"article",id:"df0oO2/550ikg",label:"Postoperative management",children:[{type:"question",id:"9FaN4m",label:"Recognize the risk factors for deep venous thrombosis in the postoperative setting, and choose the appropriate prophylactic therapy.",children:[]}]},{type:"article",id:"df0oO2/M50Mkg",label:"Aortic dissection",children:[{type:"question",id:"1k025T",label:"Recognize aortic dissection, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"QD0uVR",label:"Recognize uncomplicated descending aortic dissection, and choose the most appropriate initial management.",children:[]},{type:"question",id:"kD0meR",label:"Recognize aortic dissection.",children:[]},{type:"question",id:"tD0XTR",label:"Recognize aortic dissection, and recall its complications.",children:[]},{type:"question",id:"DD01gR",label:"Recognize aortic dissection, and recall its risk factors.",children:[]},{type:"question",id:"C5aqmO",label:"Recognize aortic dissection, and recall its primary risk factor.",children:[]},{type:"question",id:"0nae7O",label:"Recognize aortic dissection by a tear in the tunica intima.",children:[]},{type:"question",id:"ssatwN",label:"Recognize acute aortic occlusion.",children:[]},{type:"question",id:"H9aKK5",label:"Recognize aortic dissection, and choose the most appropriate diagnostic test in a hemodynamically stable patient.",children:[]},{type:"question",id:"U-ab9M",label:"Recognize Stanford A aortic dissection, and choose the most appropriate management.",children:[]}]},{type:"article",id:"df0oO2/I50Ylg",label:"Atrioventricular block",children:[{type:"question",id:"wG0hY3",label:"Recognize first-degree atrioventricular block, and choose the most appropriate cardiovascular management.",children:[]},{type:"question",id:"zF0rk3",label:"Recognize Mobitz type I AV block.",children:[]},{type:"question",id:"Z80ZO3",label:"Choose the most appropriate management for hemodynamically unstable bradyarrhythmia.",children:[]},{type:"question",id:"L80wM3",label:"Recognize third-degree atrioventricular block, and choose the most appropriate next step in management.",children:[]},{type:"question",id:"uz0pui",label:"Recognize complete heart block, and recall the hierarchy of pacemakers in the cardiac conduction system.",children:[]},{type:"question",id:"frakgN",label:"Recognize third-degree atrioventricular block.",children:[]}]},{type:"article",id:"df0oO2/w50hmg",label:"Pulmonary hypertension and cor pulmonale",children:[{type:"question",id:"Um0bUg",label:"Recognize mitral stenosis, and recall its hemodynamic consequences.",children:[]},{type:"question",id:"pD0L2R",label:"Recognize pulmonary hypertension, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"mC0VsR",label:"Recognize chronic pulmonary hypertension as a cause of fluid retention.",children:[]},{type:"question",id:"w_0hqi",label:"Recognize right heart failure due to pulmonary 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deposition.",children:[]}]},{type:"article",id:"df0oO2/rM0fJg",label:"Cardiovascular examination",children:[{type:"question",id:"_o05eS",label:"Recognize a venous hum.",children:[]},{type:"question",id:"iq0JyS",label:"Recognize benign heart murmurs in children, and recall the characteristics of a central venous hum.",children:[]},{type:"question",id:"Rx0lwR",label:"Recognize a diastolic murmur, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"4A03Pi",label:"Recognize Marfan syndrome, and recall the auscultation location for mitral valve prolapse.",children:[]},{type:"question",id:"R_0lLi",label:"Recognize pulsus paradoxus in asthma.",children:[]},{type:"question",id:"I_0Ypi",label:"Recognize atrial fibrillation, and recall its effects on the jugular venous pressure waveform.",children:[]},{type:"question",id:"-ZaDVQ",label:"Recognize the clinical features of heart failure, and recall the cause of a third heart sound (S3).",children:[]},{type:"question",id:"c5aaQO",label:"Recognize decreased compliance of the left ventricle.",children:[]},{type:"question",id:"B5azmO",label:"Recognize a fourth heart sound (S4), and recall its causes.",children:[]},{type:"question",id:"z5ar5O",label:"Recognize left ventricular failure as a cause of S3 heart sound.",children:[]},{type:"question",id:"jJa_Fl",label:"Recognize the cause of a loud S1 heart sound.",children:[]},{type:"question",id:"UGabAN",label:"Recognize decreased compliance of the left ventricle.",children:[]},{type:"question",id:"zGarbm",label:"Recognize physiologic splitting of S2 during inspiration.",children:[]}]},{type:"article",id:"df0oO2/tM0Xqg",label:"Congenital immunodeficiency disorders",children:[{type:"question",id:"9o0NVS",label:"Recognize DiGeorge syndrome, and recall its associated laboratory finding.",children:[]}]},{type:"article",id:"df0oO2/sL0t_g",label:"Nonthrombotic embolism",children:[{type:"question",id:"UwabR5",label:"Recognize 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complications.",children:[]},{type:"question",id:"MYaMpQ",label:"Recognize mitral stenosis, and recall its hemodynamic consequences.",children:[]},{type:"question",id:"pUaLVP",label:"Recognize mitral stenosis, and recall the anatomical relationship of the left atrium.",children:[]},{type:"question",id:"e5axQO",label:"Recognize antibody cross-reactivity in rheumatic heart disease.",children:[]},{type:"question",id:"U5abjO",label:"Recognize mitral stenosis, and recall the relationship between LAP and the timing of the opening snap.",children:[]},{type:"question",id:"HLaK_O",label:"Recognize mitral stenosis, and recall its associated changes on a left ventricular pressure-volume loop graph.",children:[]},{type:"question",id:"BoazVl",label:"Recognize mitral valve stenosis.",children:[]}]},{type:"article",id:"df0oO2/9L0N-g",label:"Atherosclerotic cardiovascular disease",children:[{type:"question",id:"smatSO",label:"Recognize acute coronary syndrome, and recall the initial step in 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risk.",children:[]}]},{type:"article",id:"df0oO2/Yo0n0S",label:"Pericarditis",children:[{type:"question",id:"VR0GNf",label:"Recognize acute pericarditis, and recall its complications.",children:[]},{type:"question",id:"2m0TUg",label:"Recognize constrictive pericarditis, and choose the most appropriate next step in management.",children:[]},{type:"question",id:"-u0DF3",label:"Recognize systemic lupus erythematosus, and recall its cardiac manifestation.",children:[]},{type:"question",id:"pC0LGR",label:"Recognize acute radiation-induced pericarditis.",children:[]},{type:"question",id:"u_0pJi",label:"Recognize constrictive pericarditis, and recall its characteristic physical examination finding.",children:[]},{type:"question",id:"gz0FHi",label:"Recognize constrictive pericarditis, and recall its auscultatory findings.",children:[]},{type:"question",id:"9-0Nzi",label:"Recognize acute viral infection as a cause of acute pericarditis.",children:[]},{type:"question",id:"-oaDel",label:"Recognize acute pericarditis, and recall its typical ECG findings.",children:[]},{type:"question",id:"n7a7mN",label:"Recognize acute pericarditis, and recall its diagnostic findings.",children:[]},{type:"question",id:"0taeXm",label:"Recognize acute pericarditis, and choose the most appropriate initial management.",children:[]},{type:"question",id:"iDaJV5",label:"Recognize purulent pericarditis post-cardiac surgery, and choose the most appropriate initial management.",children:[]}]},{type:"article",id:"df0oO2/To06YS",label:"Cardiac myxoma",children:[{type:"question",id:"p40L4T",label:"Recognize cardiac myxoma.",children:[]},{type:"question",id:"uA0pli",label:"Recognize a cardiac tumor presenting with syncope and orthostatic hypotension.",children:[]},{type:"question",id:"o1a03j",label:"Recognize cardiac myxoma, and recall its common site of origin.",children:[]},{type:"question",id:"SOay7k",label:"Recognize cardiac 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severity.",children:[]},{type:"question",id:"LZawXQ",label:"Recognize transposition of the great arteries, and recall the maternal condition associated with its development.",children:[]},{type:"question",id:"W0aPUQ",label:"Recognize right ventricular outflow obstruction.",children:[]},{type:"question",id:"yYad7Q",label:"Recognize a cyanotic spell in tetralogy of Fallot, and choose the initial management.",children:[]},{type:"question",id:"AYaR7Q",label:"Recognize tetralogy of Fallot, and recall its characteristic ECG finding.",children:[]},{type:"question",id:"IVaYDj",label:"Recognize persistent truncus arteriosus, and recall its embryological origin.",children:[]},{type:"question",id:"lUavWP",label:"Recognize transposition of the great vessels, and recall its embryological origin.",children:[]},{type:"question",id:"FQagB4",label:"Recognize transposition of the great vessels, and choose the most appropriate pharmacotherapy to maintain ductal patency.",children:[]}]},{type:"article",id:"df0oO2/No0-XS",label:"Abdominal aortic aneurysm",children:[{type:"question",id:"xk0EJT",label:"Recognize ruptured abdominal aortic aneurysm, and recall its strongest independent risk factor.",children:[]},{type:"question",id:"wO0huT",label:"Recognize ruptured abdominal aortic aneurysm, and choose the most appropriate management in a hemodynamically unstable patient.",children:[]},{type:"question",id:"MD0MUR",label:"Recognize abdominal aortic aneurysm, and choose the most appropriate diagnostic test.",children:[]},{type:"question",id:"nD07UR",label:"Recognize indications for abdominal aortic aneurysm repair, and choose the most appropriate surgical intervention.",children:[]},{type:"question",id:"9WaNnj",label:"Recognize a ruptured abdominal aortic aneurysm, and recall its pathophysiology.",children:[]},{type:"question",id:"75a4lO",label:"Recognize abdominal aortic aneurysm, and recall its pathological process.",children:[]},{type:"question",id:"jFa_3m",label:"Choose the most appropriate screening for a 66-year-old former smoker.",children:[]}]},{type:"article",id:"df0oO2/qo0C1S",label:"Signal transduction",children:[{type:"question",id:"ZMaZMO",label:"Recall the mechanism of action of B-type natriuretic peptide, and recall the intracellular effects of cGMP.",children:[]}]},{type:"article",id:"df0oO2/so0tWS",label:"Muscle tissue",children:[{type:"question",id:"VfaGOP",label:"Recall the role of T-tubule density in cardiac excitation-contraction coupling.",children:[]},{type:"question",id:"fgakuP",label:"Recall the effects of ACE inhibitors on nitric oxide production.",children:[]}]},{type:"article",id:"df0oO2/vo0AdS",label:"Embryogenesis",children:[{type:"question",id:"ITaYHP",label:"Recognize patent ductus arteriosus, and recall its embryological origin.",children:[]}]},{type:"article",id:"df0oO2/9o0NVS",label:"Resting potentials and action 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myocardial oxygen demand.",children:[]},{type:"question",id:"9TaNGP",label:"Calculate the mean arterial pressure, cardiac output, and ejection fraction.",children:[]},{type:"question",id:"HPaKTk",label:"Calculate flow velocity.",children:[]},{type:"question",id:"tMaXqO",label:"Recognize aortic stenosis, and recall the effects of atrial fibrillation on ventricular preload.",children:[]},{type:"question",id:"-naDDO",label:"Recall the continuity equation for fluid dynamics.",children:[]},{type:"question",id:"qLaCAO",label:"Recognize mitral stenosis, and recall mitral valve opening timing relative to left ventricular pressure-volume changes during the cardiac cycle.",children:[]},{type:"question",id:"PJaW8l",label:"Recognize aortic valve regurgitation.",children:[]}]},{type:"article",id:"df0oO2/T6064S",label:"Larynx",children:[{type:"question",id:"gmaFUO",label:"Recall the anatomy of the superior thyroid artery, and recall its 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lungs",children:[{type:"question",id:"udap7j",label:"Recall the arterial supply route to the bronchial arteries from the femoral artery.",children:[]}]},{type:"article",id:"df0oO2/Up0bKS",label:"Heart",children:[{type:"question",id:"F_0gJi",label:"Recognize aortic dissection, and recall its embryological origin.",children:[]},{type:"question",id:"nSa7Z4",label:"Recognize pacemaker syndrome, and recall the typical pacemaker lead placement in a single-chamber device.",children:[]},{type:"question",id:"y5ad5O",label:"Recall the timing of peak coronary blood flow in relation to pressure changes during the cardiac cycle.",children:[]}]},{type:"article",id:"df0oO2/Op0IpS",label:"Thoracic cavity",children:[{type:"question",id:"Ema8hO",label:"Recognize the utility of transesophageal echocardiography, and recall the anatomical structures it evaluates.",children:[]}]},{type:"article",id:"df0oO2/iJ0JFS",label:"Ischemic stroke",children:[{type:"question",id:"to0XdS",label:"Recognize paradoxical embolism, and recall the diagnostic finding of the associated cardiac anomaly.",children:[]}]},{type:"article",id:"df0oO2/jJ0_FS",label:"Vascular physiology",children:[{type:"question",id:"BZazdQ",label:"Recognize the effects of atrial natriuretic peptide, and recall its influence on sodium reabsorption.",children:[]},{type:"question",id:"zZarVQ",label:"Recognize right heart failure, and recall the pathophysiology of edema formation.",children:[]},{type:"question",id:"mhaVe4",label:"Recall the effects of adenosine and lactate on vascular resistance during exercise.",children:[]},{type:"question",id:"epaxol",label:"Recall the role of adenosine in exercise-induced vasodilation.",children:[]}]},{type:"article",id:"df0oO2/6J0jES",label:"Management of bradycardia",children:[{type:"question",id:"dt0oc3",label:"Choose the first-line treatment for unstable bradycardia.",children:[]}]},{type:"article",id:"df0oO2/Yq0nCS",label:"Acute coronary 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cardiomyopathy, and recall its echocardiographic findings.",children:[]},{type:"question",id:"0-0eDi",label:"Recall the mechanism of left ventricular hypertrophy due to chronic hypertension.",children:[]},{type:"question",id:"Rlal9k",label:"Recognize hypertrophic cardiomyopathy, and recall its characteristic echocardiographic finding.",children:[]},{type:"question",id:"Doa1Vl",label:"Recognize asymmetric septal hypertrophy in hypertrophic cardiomyopathy.",children:[]},{type:"question",id:"rKaf3l",label:"Recognize chronic hypertension as a cause of concentric left ventricular hypertrophy.",children:[]},{type:"question",id:"w8ahKm",label:"Recognize hypertrophic obstructive cardiomyopathy, and choose the most appropriate treatment to prevent sudden cardiac death.",children:[]}]},{type:"article",id:"df0oO2/vr0AQh",label:"Heparin-induced thrombocytopenia",children:[{type:"question",id:"Bx0zAR",label:"Recognize heparin-induced thrombocytopenia (HIT).",children:[]}]},{type:"article",id:"df0oO2/X7094h",label:"Transfusion reactions",children:[{type:"question",id:"C80qK3",label:"Recognize transfusion-associated circulatory overload (TACO).",children:[]}]},{type:"article",id:"df0oO2/OH0Iqh",label:"Drug overview",children:[{type:"question",id:"-5aD5O",label:"Recognize hydralazine use in pregnancy, and recall its mechanism of action.",children:[]}]},{type:"article",id:"df0oO2/3G0S_h",label:"Atrial fibrillation with rapid ventricular response",children:[{type:"question",id:"yG0db3",label:"Recognize unstable atrial fibrillation, and choose the most appropriate acute management.",children:[]},{type:"question",id:"ht0cW3",label:"Recognize stable atrial fibrillation, and choose the most appropriate rate control medication.",children:[]},{type:"question",id:"8saO9N",label:"Recognize atrial fibrillation in the context of mitral stenosis, and choose the most appropriate diagnostic procedure.",children:[]}]},{type:"article",id:"df0oO2/JF0sQ3",label:"Cardiovascular drug poisoning",children:[{type:"question",id:"dE0ou3",label:"Recognize digoxin toxicity, and recall its ECG findings.",children:[]},{type:"question",id:"vE0Ax3",label:"Recognize beta blocker overdose, and choose the next step in management after atropine.",children:[]},{type:"question",id:"rbafEQ",label:"Recognize beta-blocker overdose, and choose the appropriate antidote when first-line treatments fail.",children:[]},{type:"question",id:"ZFaZgm",label:"Recognize digitalis toxicity.",children:[]}]},{type:"article",id:"df0oO2/Yu0np3",label:"Cholesterol embolization syndrome",children:[{type:"question",id:"Eu08G3",label:"Recognize cholesterol embolization syndrome.",children:[]},{type:"question",id:"vu0AG3",label:"Recognize cholesterol embolization syndrome, and recall its risk of renal complications.",children:[]},{type:"question",id:"X0a9eQ",label:"Recognize cholesterol embolization 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pharmacotherapy.",children:[]}]},{type:"article",id:"Uf0bl2/ff0kl2",label:"Chlamydia infections",children:[{type:"question",id:"XUa9bP",label:"Recognize psittacosis, and recall its causal organism.",children:[]},{type:"question",id:"4ka3Lk",label:"Recognize Chlamydophila pneumoniae infection, and recall its resistance to beta-lactam antibiotics.",children:[]},{type:"question",id:"FHagHN",label:"Recognize Chlamydia trachomatis infection in neonates, and recall its clinical manifestations.",children:[]}]},{type:"article",id:"Uf0bl2/Of0Im2",label:"Anthrax",children:[{type:"question",id:"0faekP",label:"Recognize inhalational anthrax, and recall its unique virulence factor.",children:[]}]},{type:"article",id:"Uf0bl2/Mf0M52",label:"Herpes virus infections",children:[{type:"question",id:"jaa_4Q",label:"Recognize nasopharyngeal carcinoma, and recall its association with Epstein-Barr virus transmission.",children:[]}]},{type:"article",id:"Uf0bl2/nf0752",label:"Cytomegalovirus 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findings.",children:[]}]},{type:"article",id:"Uf0bl2/7f04n2",label:"Aspergillosis",children:[{type:"question",id:"1h021f",label:"Recognize invasive aspergillosis, and choose the most appropriate initial pharmacotherapy.",children:[]},{type:"question",id:"Kh0UUf",label:"Recognize chronic pulmonary aspergillosis.",children:[]},{type:"question",id:"2jaT-4",label:"Recognize invasive aspergillosis, and recall its characteristic histopathological features.",children:[]},{type:"question",id:"AlaRzk",label:"Recognize chronic pulmonary aspergillosis, and recall its pathogenesis.",children:[]},{type:"question",id:"bNaH-k",label:"Recognize allergic bronchopulmonary aspergillosis, and recall its characteristic sputum findings.",children:[]},{type:"question",id:"SHaypN",label:"Recognize allergic bronchopulmonary aspergillosis, and choose the most appropriate pharmacotherapy.",children:[]}]},{type:"article",id:"Uf0bl2/Af0RK2",label:"Poisoning",children:[{type:"question",id:"ex0xvR",label:"Recognize 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management.",children:[]},{type:"question",id:"9C0N8R",label:"Recognize acute respiratory distress syndrome (ARDS).",children:[]},{type:"question",id:"az0Qri",label:"Recognize acute respiratory distress syndrome, and recall its long-term complications.",children:[]},{type:"question",id:"qkaCKk",label:"Recognize acute pancreatitis complications, and recall the pathophysiology of acute respiratory distress syndrome.",children:[]},{type:"question",id:"IkaY6k",label:"Recognize ARDS due to aspiration pneumonia, and recall its effect on pulmonary shunt fraction.",children:[]},{type:"question",id:"BOazuk",label:"Recognize acute respiratory distress syndrome (ARDS), and recall its diagnostic findings.",children:[]}]},{type:"article",id:"Uf0bl2/vg0AC2",label:"Gastroesophageal reflux disease",children:[{type:"question",id:"Cw0qOR",label:"Recognize gastroesophageal reflux disease as a comorbidity of asthma, and choose the most appropriate addition to management.",children:[]}]},{type:"article",id:"Uf0bl2/rS0faf",label:"Heart failure",children:[{type:"question",id:"2MaTLO",label:"Recognize orthopnea as a symptom of left-sided heart failure.",children:[]},{type:"question",id:"bLaHwO",label:"Recognize acute cardiogenic pulmonary edema, and recall its pathophysiology.",children:[]}]},{type:"article",id:"Uf0bl2/hh0cdf",label:"Acute bronchitis",children:[{type:"question",id:"k30mif",label:"Recognize acute bronchitis, and choose the most appropriate management.",children:[]}]},{type:"article",id:"Uf0bl2/3h0Sdf",label:"Chronic obstructive pulmonary disease",children:[{type:"question",id:"oG00Z3",label:"Recognize chronic obstructive pulmonary disease (COPD).",children:[]},{type:"question",id:"AG0Rb3",label:"Recognize emphysema as a cause of obstructive lung pathology with decreased DLCO.",children:[]},{type:"question",id:"Xt09X3",label:"Recognize elevated pulmonary arterial pressure as a cause of cor pulmonale in COPD.",children:[]},{type:"question",id:"5t0iV3",label:"Recognize chronic bronchitis, and recall its findings on pulmonary function testing.",children:[]},{type:"question",id:"HC0KtR",label:"Recognize chronic bronchitis in a smoker with a persistent productive cough.",children:[]},{type:"question",id:"GC0BtR",label:"Recognize chronic obstructive pulmonary disease, and recall its impact on diaphragmatic function.",children:[]},{type:"question",id:"EC08FR",label:"Recognize chronic obstructive pulmonary disease (COPD), and recall its pathophysiology.",children:[]},{type:"question",id:"jy0_Ui",label:"Recognize chronic bronchitis, and recall its histological findings.",children:[]},{type:"question",id:"VaaGjQ",label:"Recognize chronic obstructive pulmonary disease (COPD).",children:[]},{type:"question",id:"BWaznj",label:"Recognize chronic obstructive pulmonary disease, and choose the intervention most likely to slow the decline in lung function.",children:[]},{type:"question",id:"OOaIsk",label:"Recognize emphysema, and recall its pulmonary function test findings.",children:[]},{type:"question",id:"lOavsk",label:"Recognize COPD, and recall its pathophysiology.",children:[]},{type:"question",id:"7Oa4Fk",label:"Recognize emphysematous COPD, and recall the role of neutrophils in its pathogenesis.",children:[]},{type:"question",id:"vlaAAk",label:"Recognize chronic bronchitis with chronic hypoxemia, and recall the associated hematologic finding.",children:[]},{type:"question",id:"VnaGHO",label:"Recognize the clinical features of COPD, and choose a drug that antagonizes vagal stimulation of the airways.",children:[]},{type:"question",id:"wnahvO",label:"Recognize emphysema in a patient with obstructive lung disease and decreased DLCO.",children:[]},{type:"question",id:"Eoa8dl",label:"Recognize clinical features and flow-volume loop findings of chronic obstructive lung disease.",children:[]},{type:"question",id:"KFaUQm",label:"Recognize the signs of COPD with cor pulmonale, and choose the most effective treatment to improve life expectancy.",children:[]},{type:"question",id:"NxY-9r",label:"Choose the most appropriate pharmacotherapy based on the severity of COPD.",children:[]}]},{type:"article",id:"Uf0bl2/ih0Jdf",label:"Bronchiectasis",children:[{type:"question",id:"6G0jZ3",label:"Recognize bronchiectasis.",children:[]},{type:"question",id:"jw0_iR",label:"Recognize bronchiectasis, and recall its complications.",children:[]},{type:"question",id:"t2aXjP",label:"Recognize bronchiectasis.",children:[]}]},{type:"article",id:"Uf0bl2/Ph0WVf",label:"Asthma",children:[{type:"question",id:"z60rnS",label:"Recognize asthma in a pediatric patient.",children:[]},{type:"question",id:"zJ0r9S",label:"Recognize new-onset asthma in the context of atopy, and choose the initial diagnostic test for a patient ≥ 6 years old.",children:[]},{type:"question",id:"R70llh",label:"Recognize intermittent asthma, and choose the most appropriate initial pharmacotherapy.",children:[]},{type:"question",id:"N70-Nh",label:"Recognize asthma, and choose the initial diagnostic test for suspected cases.",children:[]},{type:"question",id:"M70Mmh",label:"Recognize new-onset asthma in adults.",children:[]},{type:"question",id:"n707mh",label:"Recognize a pseudoallergic reaction.",children:[]},{type:"question",id:"QcauXj",label:"Recognize asthma, and recall the primary site of inflammation.",children:[]},{type:"question",id:"eOaxrk",label:"Recall the mechanism of action of leukotriene receptor antagonists.",children:[]},{type:"question",id:"_la5zk",label:"Recognize extrinsic asthma, and recall common environmental allergens.",children:[]},{type:"question",id:"umaphO",label:"Recognize the use of bronchoprovocative testing in diagnosing asthma.",children:[]},{type:"question",id:"Bmaz3O",label:"Recognize symptoms suggestive of asthma, and choose the most appropriate initial diagnostic test.",children:[]},{type:"question",id:"-MaDrO",label:"Choose the first-line treatment for persistent asthma.",children:[]},{type:"question",id:"anaQ7O",label:"Recognize aspirin-exacerbated respiratory disease, and recall its reaction mechanism.",children:[]},{type:"question",id:"Ynan7O",label:"Choose the most appropriate initial pharmacotherapy for acute asthma exacerbation.",children:[]},{type:"question",id:"BxazA5",label:"Recognize allergic asthma, and recall its associated triggers.",children:[]},{type:"question",id:"XBa9z5",label:"Choose the most appropriate pharmacotherapy for mild persistent asthma during pregnancy.",children:[]}]},{type:"article",id:"Uf0bl2/kh0mVf",label:"Hypersensitivity pneumonitis",children:[{type:"question",id:"0Xae9Q",label:"Recognize hypersensitivity pneumonitis, and recall its underlying immune mechanism.",children:[]},{type:"question",id:"o9Y0or",label:"Distinguish hypersensitivity pneumonitis from other causes of chronic cough.",children:[]}]},{type:"article",id:"Uf0bl2/Oh0IVf",label:"Silicosis",children:[{type:"question",id:"3-0SCi",label:"Recognize chronic silicosis, and recall its associated occupational exposure.",children:[]},{type:"question",id:"VQaGE4",label:"Recognize silicosis, and recall its complications.",children:[]},{type:"question",id:"g8aFNm",label:"Recognize silicosis in a patient with occupational exposure.",children:[]}]},{type:"article",id:"Uf0bl2/lh0vVf",label:"Asbestos-related diseases",children:[{type:"question",id:"EG08a3",label:"Recognize bronchogenic carcinoma associated with asbestosis and smoking.",children:[]},{type:"question",id:"_G05b3",label:"Recognize occupational exposure as a risk factor for asbestosis.",children:[]},{type:"question",id:"Qt0uW3",label:"Recognize asbestosis, and recall its expected pulmonary function test finding.",children:[]},{type:"question",id:"Cz0qEi",label:"Recognize asbestosis, and recall its risk factors.",children:[]},{type:"question",id:"6-0jyi",label:"Recognize malignant pleural mesothelioma, and recall its histopathological features.",children:[]},{type:"question",id:"EZa8WQ",label:"Recognize asbestosis, and recall its associated malignancies.",children:[]},{type:"question",id:"EEa8xm",label:"Recognize mesothelioma associated with asbestos exposure.",children:[]}]},{type:"article",id:"Uf0bl2/Nh0-Vf",label:"Interstitial lung diseases",children:[{type:"question",id:"Mt0MV3",label:"Recognize diffuse systemic sclerosis, and recall its effect on pulmonary function.",children:[]},{type:"question",id:"rUafeP",label:"Recognize pulmonary fibrosis, and recall its underlying mechanism.",children:[]},{type:"question",id:"Nla-Ck",label:"Recognize pulmonary fibrosis.",children:[]},{type:"question",id:"vNaA1O",label:"Recognize radiation-induced pulmonary fibrosis.",children:[]},{type:"question",id:"aLaQwO",label:"Recognize systemic lupus erythematosus, and recall its pulmonary manifestations.",children:[]},{type:"question",id:"87aOnN",label:"Recognize black lung disease, and recall the risk factor for this pneumoconiosis.",children:[]},{type:"question",id:"XFa9gm",label:"Recognize interstitial lung disease.",children:[]}]},{type:"article",id:"Uf0bl2/mh0Vef",label:"Pneumonia",children:[{type:"question",id:"si0tGf",label:"Recognize community-acquired bacterial pneumonia, and recall its common causal organism in HIV-positive patients with a normal CD4+ count.",children:[]},{type:"question",id:"_Q05Af",label:"Choose the most appropriate management for community-acquired pneumonia based on CURB-65 score.",children:[]},{type:"question",id:"zQ0rAf",label:"Recognize atypical pneumonia, and recall the common pathogens associated with it.",children:[]},{type:"question",id:"bj0H_f",label:"Choose the most appropriate pharmacotherapy for community-acquired pneumonia with suspected Pseudomonas aeruginosa infection.",children:[]},{type:"question",id:"Xj09_f",label:"Recognize postoperative pneumonia.",children:[]},{type:"question",id:"gj0F-f",label:"Recognize aspiration pneumonia, and recall its risk factors related to stroke.",children:[]},{type:"question",id:"jj0_ZT",label:"Recognize recurrent pneumonia in the same location, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"mj0VaT",label:"Recognize community-acquired pneumonia, and choose the most appropriate setting of care and treatment.",children:[]},{type:"question",id:"rj0fbT",label:"Recognize pneumonia in a long-term care resident, and recall the expected Gram stain findings.",children:[]},{type:"question",id:"lk0vLT",label:"Choose the most appropriate next step in management of viral lower respiratory infection.",children:[]},{type:"question",id:"zl0rzT",label:"Recall the effects of body positioning on the A-a gradient in pneumonia.",children:[]},{type:"question",id:"I50Ylg",label:"Recognize aspiration pneumonia.",children:[]},{type:"question",id:"p0aLSQ",label:"Recognize aspiration pneumonia, and recall its risk factors related to neurodegenerative disease.",children:[]},{type:"question",id:"paaLlQ",label:"Recognize aspiration pneumonia.",children:[]},{type:"question",id:"K2aUiP",label:"Recognize fibrinous pleuritis, and recall its microscopic findings.",children:[]},{type:"question",id:"JTas7P",label:"Choose the most appropriate pharmacotherapy for community-acquired pneumonia with suspected Pseudomonas aeruginosa infection.",children:[]},{type:"question",id:"VlaGDk",label:"Recognize the stage of lobar pneumonia, and recall the microscopic findings of gray hepatization.",children:[]},{type:"question",id:"ZNaZ-k",label:"Recognize typical bronchopneumonia, and recall the expected sputum culture findings.",children:[]},{type:"question",id:"dNaoZO",label:"Recognize cold agglutinin disease, and recall its associated infectious agent.",children:[]},{type:"question",id:"INaYcO",label:"Recognize aspiration pneumonia, and recall the most common pulmonary infiltrate location.",children:[]},{type:"question",id:"voaAdl",label:"Recognize community-acquired lobar pneumonia, and recall its most common causal pathogen.",children:[]},{type:"question",id:"pCaLG5",label:"Recognize community-acquired pneumonia, and choose the initial diagnostic test.",children:[]},{type:"question",id:"yCadu5",label:"Choose the most appropriate management for community-acquired pneumonia in a pregnant patient with comorbidities.",children:[]}]},{type:"article",id:"Uf0bl2/5h0ief",label:"Tuberculosis",children:[{type:"question",id:"JQ0sCf",label:"Choose the most appropriate screening test for latent tuberculosis infection in a patient with prior BCG vaccination.",children:[]},{type:"question",id:"qQ0CCf",label:"Recognize a positive PPD skin test in a high-risk patient, and choose the initial step to differentiate between latent and active tuberculosis.",children:[]},{type:"question",id:"IQ0Yxf",label:"Choose the most appropriate treatment for latent tuberculosis infection.",children:[]},{type:"question",id:"BQ0zyf",label:"Recognize pulmonary tuberculosis as the cause of exudative pleural effusion in an HIV-positive patient.",children:[]},{type:"question",id:"6j0jYT",label:"Recognize suspected reactivation tuberculosis, and choose the initial diagnostic test.",children:[]},{type:"question",id:"Ip0YIS",label:"Recognize latent tuberculosis infection, and choose the most appropriate management in a child with a positive interferon-γ release assay.",children:[]},{type:"question",id:"WnaPHO",label:"Recognize primary tuberculosis presenting with a Ghon complex.",children:[]},{type:"question",id:"dnaoHO",label:"Recognize reactivation tuberculosis, and recall the conditions favoring its development.",children:[]},{type:"question",id:"gFaFhm",label:"Choose the initial treatment regimen for active tuberculosis.",children:[]},{type:"question",id:"3FaS3m",label:"Recognize primary tuberculosis in an HIV-positive patient.",children:[]},{type:"question",id:"1va2_m",label:"Choose the initial management for latent TB infection in children with significant TB exposure.",children:[]}]},{type:"article",id:"Uf0bl2/Mh0Mef",label:"Sarcoidosis",children:[{type:"question",id:"CO0quT",label:"Recognize sarcoidosis.",children:[]},{type:"question",id:"OF0IR3",label:"Recognize granulomatous inflammation as a cause of sarcoidosis.",children:[]},{type:"question",id:"nF07i3",label:"Recognize asymptomatic pulmonary sarcoidosis, and choose the most appropriate management.",children:[]},{type:"question",id:"IiaYG4",label:"Recognize sarcoidosis, and recall its diagnostic findings.",children:[]},{type:"question",id:"mjaVak",label:"Recognize sarcoidosis, and recall its underlying mechanism.",children:[]},{type:"question",id:"vnaAEO",label:"Recognize sarcoidosis, and recall its associated laboratory finding.",children:[]}]},{type:"article",id:"Uf0bl2/nh07ef",label:"Lung cancer",children:[{type:"question",id:"_g05B2",label:"Recognize an intermediate-risk solitary pulmonary nodule, and choose the most appropriate diagnostic test.",children:[]},{type:"question",id:"Uh0bWf",label:"Recognize lung squamous cell carcinoma, and recall its histological features.",children:[]},{type:"question",id:"pn0L8g",label:"Recognize lung cancer as a cause of superior vena cava syndrome.",children:[]},{type:"question",id:"nt07V3",label:"Recognize symptoms of a Pancoast tumor, and recall its associated paraneoplastic syndromes.",children:[]},{type:"question",id:"a80QO3",label:"Recognize a solitary pulmonary nodule, and choose the most appropriate initial step in management.",children:[]},{type:"question",id:"Y80nO3",label:"Recognize squamous cell lung carcinoma.",children:[]},{type:"question",id:"c80al3",label:"Recognize adenocarcinoma of the lung.",children:[]},{type:"question",id:"O80I53",label:"Recognize an incidental solitary pulmonary nodule, and choose the most appropriate diagnostic test.",children:[]},{type:"question",id:"l80v53",label:"Recognize an incidental solitary pulmonary nodule with low risk for malignancy, and choose the most appropriate management.",children:[]},{type:"question",id:"580iM3",label:"Recognize limited-stage small cell lung cancer, and choose the most appropriate combined treatment modality.",children:[]},{type:"question",id:"62ajiP",label:"Recognize squamous cell lung carcinoma.",children:[]},{type:"question",id:"eRaxN4",label:"Recognize small cell lung cancer, and recall its associated immunohistochemical markers.",children:[]},{type:"question",id:"rkaf6k",label:"Recognize adenocarcinoma of the lung.",children:[]},{type:"question",id:"HkaK6k",label:"Recognize adenocarcinoma in situ of the lung.",children:[]},{type:"question",id:"Ylanvk",label:"Recognize a pulmonary 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deficiency, and recall its complications.",children:[]}]},{type:"article",id:"Uf0bl2/WQ0PEf",label:"Infection prevention and control",children:[{type:"question",id:"28aTNm",label:"Recognize the need for airborne precautions for patients with active tuberculosis.",children:[]}]},{type:"article",id:"Uf0bl2/Hj0KbT",label:"Epistaxis",children:[{type:"question",id:"J40s4T",label:"Recognize severe posterior epistaxis, and choose the most appropriate surgical intervention.",children:[]},{type:"question",id:"VhaG14",label:"Recall the arterial supply to the nasal cavity, and recall the management of posterior epistaxis.",children:[]}]},{type:"article",id:"Uf0bl2/sj0tbT",label:"Sinusitis",children:[{type:"question",id:"AR0Rpf",label:"Recognize acute bacterial rhinosinusitis, and choose the most appropriate antibiotic therapy.",children:[]},{type:"question",id:"Sw0yRR",label:"Recognize nasal polyposis in aspirin-exacerbated respiratory disease (AERD).",children:[]},{type:"question",id:"DHa1sN",label:"Recognize acute viral rhinosinusitis, and choose the most appropriate management.",children:[]},{type:"question",id:"xtaEfm",label:"Recognize secondary bacterial infection as a cause of sinusitis.",children:[]}]},{type:"article",id:"Uf0bl2/vj0AXT",label:"Nonallergic rhinitis",children:[{type:"question",id:"Tw06RR",label:"Choose the most appropriate management for vasomotor rhinitis.",children:[]}]},{type:"article",id:"Uf0bl2/wj0hcT",label:"Acute tonsillitis and pharyngitis",children:[{type:"question",id:"iT0Jq2",label:"Recognize Ludwig angina.",children:[]},{type:"question",id:"pi0Lsf",label:"Choose an alternative antibiotic for acute bacterial tonsillitis in patients with a severe penicillin allergy.",children:[]},{type:"question",id:"g50Fjg",label:"Recognize acute tonsillitis with a negative rapid strep test, and choose the most appropriate diagnostic test to confirm the infection.",children:[]},{type:"question",id:"Qqauyl",label:"Recognize acute viral pharyngitis, and choose the most appropriate management.",children:[]}]},{type:"article",id:"Uf0bl2/Cj0qcT",label:"Pharyngeal cancer",children:[{type:"question",id:"mvaV05",label:"Recognize tonsillar cancer, and recall its strongest predisposing factor.",children:[]}]},{type:"article",id:"Uf0bl2/xj0EcT",label:"Juvenile nasopharyngeal angiofibroma",children:[{type:"question",id:"oJ00ES",label:"Recognize juvenile nasopharyngeal angiofibroma, and choose the most appropriate diagnostic study.",children:[]}]},{type:"article",id:"Uf0bl2/zj0r1T",label:"Benign laryngeal lesions",children:[{type:"question",id:"twaXk5",label:"Recognize laryngeal papillomatosis.",children:[]}]},{type:"article",id:"Uf0bl2/ZP0ZWT",label:"Laryngeal carcinoma",children:[{type:"question",id:"v8aAom",label:"Recognize laryngeal squamous cell carcinoma.",children:[]}]},{type:"article",id:"Uf0bl2/VP0GdT",label:"Cellular changes and adaptive 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management.",children:[]},{type:"question",id:"CG0qY3",label:"Recognize severe asthma exacerbation, and recall its physical examination findings.",children:[]},{type:"question",id:"Ena8EO",label:"Recognize a severe asthma attack, and recall its physical examination findings.",children:[]}]},{type:"article",id:"Uf0bl2/yr0dPh",label:"Hemoptysis",children:[{type:"question",id:"S50yjg",label:"Recognize massive hemoptysis and a pulmonary nodule, and choose the most appropriate diagnostic procedure after stabilization.",children:[]}]},{type:"article",id:"Uf0bl2/X7094h",label:"Transfusion reactions",children:[{type:"question",id:"E8a8om",label:"Recognize transfusion-related acute lung injury.",children:[]}]},{type:"article",id:"Uf0bl2/_G05b3",label:"Bacterial tracheitis",children:[{type:"question",id:"AxYR_r",label:"Recognize bacterial tracheitis, and recall the most common causal pathogen.",children:[]}]},{type:"article",id:"Uf0bl2/Ct0qf3",label:"Facial 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syndrome.",children:[]}]},{type:"article",id:"ef0xO2/ZR0Zlf",label:"Meningitis",children:[{type:"question",id:"rS0faf",label:"Choose the most appropriate empiric pharmacotherapy for bacterial meningitis in an immunocompromised adult patient.",children:[]},{type:"question",id:"Wi0Pqf",label:"Choose the appropriate management for bacterial meningitis, and recall prophylaxis for close contacts.",children:[]},{type:"question",id:"hi0crf",label:"Recognize aseptic meningitis, and recall its common viral etiologies.",children:[]},{type:"question",id:"3i0Srf",label:"Recognize neonatal fever with signs of sepsis, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"Ji0ssf",label:"Recognize meningococcal meningitis, and recall its complications.",children:[]},{type:"question",id:"8i0Otf",label:"Choose the most appropriate initial antibiotic regimen for late-onset neonatal bacterial meningitis.",children:[]},{type:"question",id:"vi0Atf",label:"Recognize bacterial 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cryptococcal meningitis in HIV patients, and choose the most appropriate initial pharmacotherapy.",children:[]},{type:"question",id:"NSa--P",label:"Recognize aseptic meningitis, and recall its common viral etiologies.",children:[]},{type:"question",id:"8RaOK4",label:"Recognize Waterhouse-Friderichsen syndrome, and recall the typical portal of entry for Neisseria meningitidis.",children:[]},{type:"question",id:"djaoz4",label:"Recognize meningococcal meningitis, and choose the appropriate post-exposure prophylaxis for close contacts.",children:[]},{type:"question",id:"gjaF-4",label:"Recognize bacterial meningitis in adults, and recall the expected Gram stain findings.",children:[]},{type:"question",id:"2naTsO",label:"Recognize cryptococcal meningoencephalitis, and recall its diagnostic findings.",children:[]},{type:"question",id:"GIaBVN",label:"Recognize Naegleria fowleri infection, and recall its route of infection.",children:[]},{type:"question",id:"IraYiN",label:"Recognize signs of 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findings.",children:[]},{type:"question",id:"1K022S",label:"Recognize acute viral encephalitis, and recall its common causal pathogen.",children:[]},{type:"question",id:"i2aJhP",label:"Recognize necrosis of the temporal lobes in herpes simplex encephalitis.",children:[]},{type:"question",id:"r2afQP",label:"Recognize acute viral encephalitis, and recall its most common cause.",children:[]},{type:"question",id:"DEa1Bm",label:"Recognize herpes simplex encephalitis, and recall the transmission risk to close contacts.",children:[]}]},{type:"article",id:"ef0xO2/cR0aNf",label:"Creutzfeldt-Jakob disease",children:[{type:"question",id:"p50LOg",label:"Distinguish Creutzfeldt-Jakob disease from other types of neurodegenerative disease.",children:[]},{type:"question",id:"hn0cGg",label:"Recognize Creutzfeldt-Jakob disease, and recall its pathogenesis.",children:[]},{type:"question",id:"mo0VcS",label:"Recognize Creutzfeldt-Jakob disease, and recall its CSF diagnostic findings.",children:[]},{type:"question",id:"YYannQ",label:"Recognize Creutzfeldt-Jakob disease, and recall its pathophysiology.",children:[]},{type:"question",id:"nea7zj",label:"Recognize Creutzfeldt-Jakob disease, and recall its characteristic histological feature.",children:[]},{type:"question",id:"wGahYm",label:"Recognize familial Creutzfeldt-Jakob disease, and choose the most appropriate intervention.",children:[]}]},{type:"article",id:"ef0xO2/1R02Nf",label:"Brain abscess",children:[{type:"question",id:"vN0A1g",label:"Recognize intracranial abscess secondary to acute otitis media, and choose the most appropriate initial diagnostic test.",children:[]},{type:"question",id:"In0Yug",label:"Recognize a pyogenic brain abscess.",children:[]},{type:"question",id:"un0pEg",label:"Recognize a pyogenic brain abscess, and choose the most appropriate next step in management.",children:[]}]},{type:"article",id:"ef0xO2/WR0PNf",label:"Multiple 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sclerosis.",children:[]},{type:"question",id:"l1avSj",label:"Recognize multiple sclerosis, and recall its immunopathogenesis.",children:[]},{type:"question",id:"Seayyj",label:"Recognize internuclear ophthalmoplegia, and recall neuroanatomy of the midbrain.",children:[]},{type:"question",id:"fRakm4",label:"Recognize multiple sclerosis, and recall its diagnostic findings.",children:[]},{type:"question",id:"9RaN64",label:"Recognize multiple sclerosis, and recall its histopathological features.",children:[]},{type:"question",id:"3OaSHk",label:"Recall the pharmacotherapy that targets CD52 in refractory multiple sclerosis.",children:[]},{type:"question",id:"rqaf-l",label:"Recall the clinical effect of baclofen.",children:[]},{type:"question",id:"gwaFR5",label:"Recognize transverse myelitis, and recall its cerebrospinal fluid findings.",children:[]},{type:"question",id:"xxYEAr",label:"Recognize acute disseminated encephalomyelitis.",children:[]},{type:"question",id:"ZBYZzr",label:"Recognize 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hematoma.",children:[]},{type:"question",id:"Btazfm",label:"Recognize rupture of the middle meningeal artery causing epidural hematoma.",children:[]}]},{type:"article",id:"ef0xO2/eR0xNf",label:"Traumatic brain injury",children:[{type:"question",id:"Nk0-LT",label:"Choose the most appropriate management for a child with a skull fracture and signs of potentially elevated intracranial pressure.",children:[]},{type:"question",id:"Gw0B4R",label:"Recall the indications for intubation, and how the Glasgow Coma Scale score is calculated.",children:[]},{type:"question",id:"nva705",label:"Recognize paroxysmal sympathetic hyperactivity.",children:[]}]},{type:"article",id:"ef0xO2/UR0bmf",label:"Overview of stroke",children:[{type:"question",id:"KN0UXg",label:"Recognize a transient ischemic attack (TIA).",children:[]},{type:"question",id:"5n0iFg",label:"Recognize left posterior cerebral artery infarct.",children:[]},{type:"question",id:"Ln0wFg",label:"Recognize right anterior cerebral artery occlusion.",children:[]},{type:"question",id:"KL0UAg",label:"Recognize symptoms of stroke, and choose the most appropriate initial diagnostic study.",children:[]},{type:"question",id:"bo0H0S",label:"Recognize a lacunar stroke in the posterior limb of the internal capsule.",children:[]},{type:"question",id:"go0FYS",label:"Recognize occlusion of the left middle cerebral artery.",children:[]},{type:"question",id:"aw0QhR",label:"Recognize hemorrhage in the right thalamus.",children:[]},{type:"question",id:"OZaIbQ",label:"Recognize the clinical presentation of an anterior cerebral artery stroke.",children:[]},{type:"question",id:"mXaVAQ",label:"Recognize stroke causing Wernicke aphasia and upper homonymous quadrantanopsia, and recall neuroanatomy of the cerebral cortex.",children:[]},{type:"question",id:"m1aVhj",label:"Recognize posterior cerebral artery infarction, and recall the expected visual field deficit.",children:[]},{type:"question",id:"X2a9TP",label:"Recognize a pure motor stroke, and recall the affected cerebral artery.",children:[]},{type:"question",id:"Q2auhP",label:"Recognize a lacunar stroke involving the subthalamic nucleus, and recall its characteristic movement disorder.",children:[]},{type:"question",id:"pSaL04",label:"Recognize a pure sensory stroke, and recall the affected brain structure.",children:[]},{type:"question",id:"khamV4",label:"Recognize conduction aphasia, and recall its associated cerebral artery.",children:[]},{type:"question",id:"HpaKIl",label:"Recognize medial medullary syndrome, and recall arterial supply of the brainstem.",children:[]},{type:"question",id:"XIa9YN",label:"Recognize a lacunar infarction of the posterior limb of the internal capsule, and recall the associated motor deficits.",children:[]},{type:"question",id:"iwaJi5",label:"Recognize hemorrhagic transformation as a complication of ischemic stroke treatment.",children:[]},{type:"question",id:"7CY4tr",label:"Recognize thalamic pain syndrome (central poststroke pain).",children:[]}]},{type:"article",id:"ef0xO2/2R0Tmf",label:"Subarachnoid hemorrhage",children:[{type:"question",id:"YO0nIT",label:"Recognize subarachnoid hemorrhage, and choose the most appropriate intervention.",children:[]},{type:"question",id:"NO0-sT",label:"Recognize subarachnoid hemorrhage, and choose the most appropriate diagnostic test when CT is inconclusive.",children:[]},{type:"question",id:"6O0jtT",label:"Recognize vasospasm as a complication of subarachnoid hemorrhage, and choose the appropriate medication to prevent this complication.",children:[]},{type:"question",id:"wl0h_T",label:"Recognize subarachnoid hemorrhage, and choose the initial diagnostic test.",children:[]},{type:"question",id:"E2a8jP",label:"Recognize complications of subarachnoid hemorrhage, and choose the appropriate prophylactic medication.",children:[]},{type:"question",id:"rRafo4",label:"Recognize subarachnoid hemorrhage, and recall its location within the meningeal layers.",children:[]}]},{type:"article",id:"ef0xO2/fR0kmf",label:"Intracerebral hemorrhage",children:[{type:"question",id:"kj0m0T",label:"Recognize intracerebral hemorrhage, and recall its strongest predisposing factor.",children:[]},{type:"question",id:"zD0rSR",label:"Recognize intracerebral hemorrhage due to hypertension.",children:[]},{type:"question",id:"CiaqF4",label:"Recognize cerebral amyloid angiopathy as a cause of spontaneous lobar intracerebral hemorrhage in the elderly.",children:[]}]},{type:"article",id:"ef0xO2/SR0ymf",label:"Cerebral venous thrombosis",children:[{type:"question",id:"_l05zT",label:"Recognize septic cavernous sinus thrombosis, and choose the appropriate empiric antibiotic therapy.",children:[]},{type:"question",id:"ola0Bk",label:"Recognize cerebral venous thrombosis.",children:[]},{type:"question",id:"soatWl",label:"Recognize cerebral venous thrombosis, and choose the most appropriate initial management.",children:[]},{type:"question",id:"-DaDS5",label:"Recognize posterior reversible encephalopathy syndrome.",children:[]}]},{type:"article",id:"ef0xO2/RR0l5f",label:"Seizures and epilepsy",children:[{type:"question",id:"OM0IKg",label:"Recognize a focal seizure with Todd paralysis.",children:[]},{type:"question",id:"fL0kCg",label:"Recognize a generalized tonic-clonic seizure, and choose the most appropriate diagnostic test.",children:[]},{type:"question",id:"TL06Cg",label:"Recognize focal seizure with impaired awareness.",children:[]},{type:"question",id:"SL0yCg",label:"Recognize postictal lactic acidosis, and recall the associated laboratory finding.",children:[]},{type:"question",id:"RL0lxg",label:"Recognize seizure-induced Todd paralysis.",children:[]},{type:"question",id:"iL0Jxg",label:"Recognize a tonic-clonic seizure, and choose the most appropriate initial diagnostic test.",children:[]},{type:"question",id:"QL0uxg",label:"Recognize cortical laminar necrosis.",children:[]},{type:"question",id:"FL0gzg",label:"Recognize a focal to bilateral tonic-clonic seizure.",children:[]},{type:"question",id:"io0JbS",label:"Recognize status epilepticus, and choose the first-line treatment.",children:[]},{type:"question",id:"sUateP",label:"Recognize complex partial seizures.",children:[]},{type:"question",id:"SkayMk",label:"Recognize status epilepticus, and choose an antiepileptic drug that alters sodium ion flow across neuronal membranes.",children:[]},{type:"question",id:"6yajTM",label:"Recognize psychogenic nonepileptic seizure, and choose the most appropriate treatment.",children:[]}]},{type:"article",id:"ef0xO2/iR0J5f",label:"Focal seizures and syndromes",children:[{type:"question",id:"9s0NCh",label:"Recognize focal seizures with impaired consciousness, and recall the expected EEG findings.",children:[]}]},{type:"article",id:"ef0xO2/jR0_5f",label:"Generalized epilepsy in childhood",children:[{type:"question",id:"VL0G9g",label:"Recognize absence seizures, and choose the most appropriate pharmacotherapy.",children:[]},{type:"question",id:"RjalZk",label:"Recognize childhood absence seizures.",children:[]},{type:"question",id:"fPakVk",label:"Recognize juvenile absence epilepsy, and choose the most appropriate pharmacotherapy.",children:[]},{type:"question",id:"Ykanmk",label:"Recognize juvenile myoclonic epilepsy, and choose the most appropriate treatment.",children:[]}]},{type:"article",id:"ef0xO2/4R03Mf",label:"Transient global amnesia",children:[{type:"question",id:"oM00pg",label:"Recognize transient global amnesia.",children:[]}]},{type:"article",id:"ef0xO2/kR0mMf",label:"Narcolepsy",children:[{type:"question",id:"PM0WKg",label:"Recognize narcolepsy, and choose the most appropriate initial pharmacotherapy.",children:[]},{type:"question",id:"9eaNaP",label:"Recognize narcolepsy, and recall its CSF findings.",children:[]},{type:"question",id:"SSay_P",label:"Recognize narcolepsy with cataplexy, and choose the most appropriate nighttime pharmacotherapy.",children:[]},{type:"question",id:"amaQVO",label:"Recognize narcolepsy, and recall its polysomnographic findings.",children:[]}]},{type:"article",id:"ef0xO2/OR0IMf",label:"Syringomyelia",children:[{type:"question",id:"Kl0UBT",label:"Recognize syringomyelia.",children:[]},{type:"question",id:"HA0KOi",label:"Recognize central cord syndrome, and recall the associated clinical finding.",children:[]},{type:"question",id:"Nha-V4",label:"Recognize syringomyelia.",children:[]}]},{type:"article",id:"ef0xO2/NR0-Mf",label:"Incomplete spinal cord syndromes",children:[{type:"question",id:"Lg0wD2",label:"Recognize central cord syndrome, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"MP0M2T",label:"Recognize Brown-S\xe9quard syndrome.",children:[]},{type:"question",id:"dk0o5T",label:"Recognize anterior spinal artery syndrome.",children:[]},{type:"question",id:"UL0bCg",label:"Recognize anterior cord syndrome, and recall its vascular supply.",children:[]},{type:"question",id:"3L0Sxg",label:"Recognize anterior spinal artery syndrome, and recall the preserved sensory function.",children:[]},{type:"question",id:"gcaFbj",label:"Recall the blood supply to the dorsal columns of the spinal cord.",children:[]},{type:"question",id:"PPaWUk",label:"Recognize partial Brown-Sequard syndrome, and recall the expected motor function findings.",children:[]},{type:"question",id:"aqaQCl",label:"Recognize anterior cord syndrome.",children:[]}]},{type:"article",id:"ef0xO2/MR0Mnf",label:"Spinal muscular atrophy",children:[{type:"question",id:"Q9auM5",label:"Recognize spinal muscular atrophy.",children:[]}]},{type:"article",id:"ef0xO2/LR0wnf",label:"Amyotrophic lateral sclerosis",children:[{type:"question",id:"RM0log",label:"Recognize amyotrophic lateral sclerosis (ALS).",children:[]},{type:"question",id:"Kn0U8g",label:"Recognize amyotrophic lateral sclerosis (ALS), and choose the most appropriate pharmacotherapy.",children:[]},{type:"question",id:"6n0j8g",label:"Recognize amyotrophic lateral sclerosis, and recall its effect on motor neurons.",children:[]},{type:"question",id:"BUaz2P",label:"Recognize amyotrophic lateral sclerosis, and recall its effects on motor neurons.",children:[]},{type:"question",id:"3TaSqP",label:"Recognize amyotrophic lateral sclerosis (ALS).",children:[]},{type:"question",id:"ERa8K4",label:"Recognize amyotrophic lateral sclerosis (ALS), and recall the pharmacotherapy that slows its progression.",children:[]},{type:"question",id:"zHarGN",label:"Choose the most appropriate next step in management before transferring a patient with ALS to hospice care.",children:[]},{type:"question",id:"0Faegm",label:"Recognize amyotrophic lateral sclerosis (ALS), and recall its respiratory complications.",children:[]},{type:"question",id:"_Ea5ym",label:"Recognize amyotrophic lateral sclerosis (ALS), and choose the most appropriate diagnostic study.",children:[]}]},{type:"article",id:"ef0xO2/KR0ULf",label:"Friedreich ataxia",children:[{type:"question",id:"BL0z-g",label:"Recognize Friedreich ataxia, and recall its complications.",children:[]},{type:"question",id:"AL0RZS",label:"Recognize Friedreich ataxia, and recall its genetic basis.",children:[]},{type:"question",id:"Leawzj",label:"Recognize Friedreich ataxia and associated hammer toes.",children:[]},{type:"question",id:"nga7DP",label:"Recognize Friedreich ataxia, and recall its most common cause of death.",children:[]},{type:"question",id:"UnabsO",label:"Recognize Friedreich ataxia, and recall its genetic cause.",children:[]}]},{type:"article",id:"ef0xO2/JR0sLf",label:"Spinal stenosis",children:[{type:"question",id:"9n0Nvg",label:"Recognize neurogenic claudication, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"zn0rDg",label:"Recognize lumbar spinal stenosis, and recall the postural change that relieves symptoms.",children:[]}]},{type:"article",id:"ef0xO2/qR0CLf",label:"Polyneuropathy",children:[{type:"question",id:"s30tPf",label:"Recognize Refsum disease, and recall its associated cellular defect.",children:[]},{type:"question",id:"wM0hIg",label:"Recognize chronic inflammatory demyelinating polyneuropathy, and recall its associated autoantibody.",children:[]},{type:"question",id:"vqaAZN",label:"Recognize polyneuropathy as a cause of sensory ataxia and hyporeflexia.",children:[]},{type:"question",id:"wEahBm",label:"Recognize symptoms of polyneuropathy, and choose the most appropriate diagnostic study.",children:[]}]},{type:"article",id:"ef0xO2/7R04of",label:"Guillain-Barr\xe9 syndrome",children:[{type:"question",id:"vT0As2",label:"Recognize Guillain-Barr\xe9 syndrome, and recall its complications.",children:[]},{type:"question",id:"Ii0YGf",label:"Recognize Guillain-Barr\xe9 syndrome, and choose the most appropriate initial treatment.",children:[]},{type:"question",id:"9maN3O",label:"Recognize Guillain-Barr\xe9 syndrome, and recall the process of nerve recovery.",children:[]},{type:"question",id:"JDas25",label:"Recognize Guillain-Barr\xe9 syndrome, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"hwaci5",label:"Recognize Miller-Fisher syndrome, and recall its pathophysiology.",children:[]}]},{type:"article",id:"ef0xO2/HR0Kof",label:"Shingles",children:[{type:"question",id:"_R05pf",label:"Recognize postherpetic neuralgia, and choose the most appropriate pharmacotherapy.",children:[]}]},{type:"article",id:"ef0xO2/sR0tof",label:"Carpal tunnel syndrome",children:[{type:"question",id:"Gg0B92",label:"Recognize median nerve compression as carpal tunnel syndrome.",children:[]},{type:"question",id:"vS0AYf",label:"Recognize carpal tunnel syndrome, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"ItaYUm",label:"Recognize carpal tunnel syndrome, and choose the most appropriate initial management.",children:[]}]},{type:"article",id:"ef0xO2/tR0XKf",label:"Cranial nerve palsies",children:[{type:"question",id:"7L04_g",label:"Recognize diabetic mononeuropathy as a cause of cranial nerve palsy, and recall that ptosis is a feature of oculomotor nerve palsy.",children:[]},{type:"question",id:"5z0iti",label:"Recognize diabetic mononeuropathy presenting as oculomotor nerve palsy, and recall the associated clinical feature of ptosis.",children:[]},{type:"question",id:"R-0lCi",label:"Recognize the functions of cranial nerve VII, and recall its role in taste and facial expressions.",children:[]},{type:"question",id:"2VaTFj",label:"Recognize trochlear nerve palsy, and recall its affected muscle.",children:[]},{type:"question",id:"LSawZ4",label:"Recognize a lesion of the mandibular branch of the trigeminal nerve, and recall the skull foramen it exits through.",children:[]},{type:"question",id:"KSaU04",label:"Recognize oculomotor nerve palsy, and recall its potential causes.",children:[]},{type:"question",id:"9SaNb4",label:"Recognize a lesion of the vagus nerve (CN X), and recall its associated physical examination findings.",children:[]},{type:"question",id:"CSaqb4",label:"Recognize a superior orbital fissure syndrome, and recall the associated cranial nerve deficits.",children:[]},{type:"question",id:"ehax14",label:"Recall the functions of the mandibular division of the trigeminal nerve (CN V3), and recall the consequences of its lesion.",children:[]},{type:"question",id:"ShayW4",label:"Recognize a paraganglioma of the jugular foramen, and recall the functions of the glossopharyngeal nerve.",children:[]},{type:"question",id:"C3aqk4",label:"Recognize Zenker diverticulum, and recall the functions of the vagus nerve.",children:[]},{type:"question",id:"sRato4",label:"Recognize anterior middle cranial fossa fracture, and recall the associated cranial nerve injuries.",children:[]},{type:"question",id:"VjaGz4",label:"Recognize compression of the maxillary nerve, and recall its sensory distribution.",children:[]},{type:"question",id:"6Oajtk",label:"Recognize impaired cough reflex due to nerve damage, and recall the anatomical site of the internal laryngeal nerve.",children:[]},{type:"question",id:"OMaIKO",label:"Recognize lateral pontine syndrome, and recall the deficits associated with trigeminal nerve involvement.",children:[]},{type:"question",id:"EJa8Dl",label:"Recognize facial nerve palsy due to a schwannoma, and recall anatomy of the cerebellopontine angle.",children:[]},{type:"question",id:"AzaRvM",label:"Recognize posterior communicating artery aneurysm as a cause of CN III palsy.",children:[]}]},{type:"article",id:"ef0xO2/FR0gKf",label:"Facial nerve palsy",children:[{type:"question",id:"eO0xrT",label:"Recognize peripheral facial nerve palsy, and choose the most appropriate next step in management.",children:[]},{type:"question",id:"xeaEaP",label:"Recognize central facial nerve palsy, and recall its characteristic neurological findings.",children:[]},{type:"question",id:"_ga5BP",label:"Recognize complications of parotidectomy, and recall the functions of the facial nerve.",children:[]},{type:"question",id:"jwa_i5",label:"Recognize Bell palsy, and recall that no further evaluation is necessary.",children:[]},{type:"question",id:"PwaWQ5",label:"Recognize the prognosis of Bell palsy, and choose the most appropriate response to a patient's concern about recovery.",children:[]}]},{type:"article",id:"ef0xO2/8R0OKf",label:"Progressive muscular dystrophies",children:[{type:"question",id:"qj0CYT",label:"Recognize Duchenne muscular dystrophy, and recall the role of dystrophin protein.",children:[]},{type:"question",id:"KhaUU4",label:"Recognize Duchenne muscular dystrophy, and recall the role of dystrophin protein.",children:[]},{type:"question",id:"qFaCQm",label:"Recognize Duchenne muscular dystrophy, and choose the most appropriate initial diagnostic test.",children:[]}]},{type:"article",id:"ef0xO2/uR0pKf",label:"Myotonic syndromes",children:[{type:"question",id:"tL0Xzg",label:"Recognize myotonic dystrophy.",children:[]},{type:"question",id:"Tia6I4",label:"Recognize myotonic dystrophy, and recall its genetic cause.",children:[]}]},{type:"article",id:"ef0xO2/DR016f",label:"Myasthenia gravis",children:[{type:"question",id:"IS0Yaf",label:"Recognize myasthenia gravis, and recall the mechanism of action of cholinesterase inhibitors.",children:[]},{type:"question",id:"7k046T",label:"Recognize an anterior mediastinal mass associated with myasthenia gravis, and recall the diagnostic antibody.",children:[]},{type:"question",id:"HL0K_g",label:"Recognize myasthenia gravis, and choose the most appropriate initial investigation.",children:[]},{type:"question",id:"Ou0Ir3",label:"Recognize myasthenic crisis, and choose the most appropriate next step in management.",children:[]},{type:"question",id:"F2agjP",label:"Recognize an anterior mediastinal mass, and recall the associated diagnostic antibody.",children:[]},{type:"question",id:"XTa96P",label:"Recognize myasthenia gravis, and recall the mechanism of action of cholinesterase inhibitors.",children:[]},{type:"question",id:"Q3auR4",label:"Recognize myasthenia gravis.",children:[]},{type:"question",id:"j3a_R4",label:"Recognize Lambert-Eaton syndrome.",children:[]},{type:"question",id:"_Na5dO",label:"Recognize Lambert-Eaton myasthenic syndrome, and recall its underlying mechanism.",children:[]},{type:"question",id:"ctaacm",label:"Recognize myasthenia gravis.",children:[]}]},{type:"article",id:"ef0xO2/9R0N6f",label:"Wernicke encephalopathy and Korsakoff syndrome",children:[{type:"question",id:"pVaLvj",label:"Recognize Wernicke encephalopathy, and recall its prevention.",children:[]},{type:"question",id:"zVarCj",label:"Recognize Wernicke encephalopathy autopsy findings.",children:[]},{type:"question",id:"wkahJk",label:"Recognize Wernicke encephalopathy, and recall the effects of administering glucose without thiamine.",children:[]},{type:"question",id:"3MaSoO",label:"Recognize Wernicke encephalopathy, and recall the role of thiamine in enzyme function.",children:[]}]},{type:"article",id:"ef0xO2/BR0z6f",label:"Cerebellar syndromes",children:[{type:"question",id:"wn0hvg",label:"Recognize cerebellar degeneration due to alcohol use.",children:[]},{type:"question",id:"1L029g",label:"Recall the clinical features of a cerebellar lesion.",children:[]},{type:"question",id:"SK0yfS",label:"Recognize acute cerebellar ataxia due to varicella-zoster virus infection, and recall its associated neurological findings.",children:[]},{type:"question",id:"17a2kN",label:"Recognize cerebellar hemisphere injury, and recall its manifestations on coordination tests.",children:[]},{type:"question",id:"W7aPkN",label:"Recognize cerebellar vermis injury, and recall its associated symptoms.",children:[]}]},{type:"article",id:"ef0xO2/AR0Rpf",label:"Ulnar nerve entrapment",children:[{type:"question",id:"jn0_Gg",label:"Recognize cubital tunnel syndrome, and recall the associated physical examination findings.",children:[]},{type:"question",id:"chaa14",label:"Recognize ulnar nerve entrapment at Guyon canal, and recall its associated hand muscle dysfunctions.",children:[]}]},{type:"article",id:"ef0xO2/_R05pf",label:"Radial neuropathies",children:[{type:"question",id:"S3ay34",label:"Recognize radial nerve injury, and recall its motor innervation.",children:[]}]},{type:"article",id:"ef0xO2/zR0rpf",label:"Median nerve neuropathy",children:[{type:"question",id:"geaFyj",label:"Recognize median nerve injury.",children:[]}]},{type:"article",id:"ef0xO2/Zi0ZJf",label:"Peripheral nerve injuries",children:[{type:"question",id:"8L0Ozg",label:"Recognize lateral femoral cutaneous syndrome (meralgia paresthetica), and choose the most appropriate management for symptom relief.",children:[]},{type:"question",id:"ho0cbS",label:"Recognize common peroneal neuropathy, and recall the expected motor function finding.",children:[]},{type:"question",id:"Yp0nLS",label:"Recognize Klumpke palsy, and recall its diagnostic findings.",children:[]},{type:"question",id:"YE0n83",label:"Recognize femoral nerve injury.",children:[]},{type:"question",id:"M_0MKi",label:"Recognize the clinical presentation of axillary nerve injury.",children:[]},{type:"question",id:"pcaLWj",label:"Recall the innervation of the hip flexors and the effects of femoral nerve block.",children:[]},{type:"question",id:"vWaAMj",label:"Recognize winged scapula, and recall the nerve that innervates the serratus anterior muscle.",children:[]},{type:"question",id:"ySadX4",label:"Recognize common peroneal nerve injury, and recall its effect on foot dorsiflexion.",children:[]},{type:"question",id:"Xha9c4",label:"Recognize injury to the right superior gluteal nerve.",children:[]},{type:"question",id:"qhaCU4",label:"Recognize musculocutaneous nerve injury, and recall the actions it controls.",children:[]},{type:"question",id:"rhaf24",label:"Recognize tibial nerve compression, and recall its sensory distribution.",children:[]},{type:"question",id:"7ha424",label:"Recognize a positive Trendelenburg sign, and recall the anatomical landmarks for safe intramuscular injection in the buttock.",children:[]},{type:"question",id:"j_0_Li",label:"Recognize musculocutaneous nerve injury, and recall the anatomy of the brachial plexus.",children:[]},{type:"question",id:"jka_nk",label:"Recall the characteristics of central chromatolysis.",children:[]},{type:"question",id:"V6aGPl",label:"Recognize long thoracic nerve injury, and recall its spinal root origin.",children:[]}]},{type:"article",id:"ef0xO2/bi0HJf",label:"Locked-in syndrome",children:[{type:"question",id:"9IaNUN",label:"Recognize locked-in syndrome, and recall the artery typically involved.",children:[]}]},{type:"article",id:"ef0xO2/1i02qf",label:"Wallenberg syndrome",children:[{type:"question",id:"4n03tg",label:"Recognize Wallenberg syndrome, and recall its associated arterial occlusion.",children:[]},{type:"question",id:"B6azMl",label:"Recognize lateral medullary syndrome, and recall its associated vascular supply.",children:[]}]},{type:"article",id:"ef0xO2/Wi0Pqf",label:"Spinal cord injuries",children:[{type:"question",id:"f50kjg",label:"Recognize spinal shock and neurogenic shock due to spinal cord injury, and choose the most appropriate initial management.",children:[]}]},{type:"article",id:"ef0xO2/Ui0bIf",label:"Horner syndrome",children:[{type:"question",id:"7Ra4o4",label:"Recognize compression of the stellate ganglion causing Horner syndrome.",children:[]}]},{type:"article",id:"ef0xO2/Ti06If",label:"Benign paroxysmal positional vertigo",children:[{type:"question",id:"_M05rg",label:"Recognize benign paroxysmal positional vertigo (BPPV).",children:[]},{type:"question",id:"HeaKZP",label:"Recognize benign paroxysmal positional vertigo (BPPV), and recall its association with nystagmus.",children:[]},{type:"question",id:"u8apom",label:"Recognize benign paroxysmal positional vertigo (BPPV), and choose the most appropriate diagnostic study.",children:[]}]},{type:"article",id:"ef0xO2/gi0FIf",label:"Meniere disease",children:[{type:"question",id:"CS0qbf",label:"Recognize Meniere disease, and recall its pathophysiology.",children:[]},{type:"question",id:"fv0kz3",label:"Recognize Meniere disease, and choose the most appropriate initial step in management.",children:[]},{type:"question",id:"vgaACP",label:"Recognize endolymphatic hydrops as the cause of M\xe9ni\xe8re disease.",children:[]}]},{type:"article",id:"ef0xO2/Si0yIf",label:"Vestibular neuritis",children:[{type:"question",id:"F9Yg6r",label:"Distinguish labyrinthitis from other causes of dizziness.",children:[]}]},{type:"article",id:"ef0xO2/hi0crf",label:"Migraine",children:[{type:"question",id:"kL0mBg",label:"Choose the most appropriate therapy for long-term prevention of migraine headaches.",children:[]},{type:"question",id:"OL0IBg",label:"Choose the most appropriate initial pharmacotherapy for acute migraine with vomiting.",children:[]},{type:"question",id:"NL0-Bg",label:"Recognize migraine in a pediatric patient, and choose the most appropriate abortive treatment.",children:[]},{type:"question",id:"fWakkj",label:"Recognize migraine headaches, and recall the mechanism of action of triptans.",children:[]},{type:"question",id:"4ja30k",label:"Recognize migraine headache.",children:[]}]},{type:"article",id:"ef0xO2/3i0Srf",label:"Tension-type headache",children:[{type:"question",id:"Sn0ysg",label:"Choose the most appropriate long-term pharmacotherapy for chronic tension headache.",children:[]},{type:"question",id:"dDaoW5",label:"Choose the most appropriate management for episodic tension-type headaches.",children:[]}]},{type:"article",id:"ef0xO2/Ri0lrf",label:"Cluster headache",children:[{type:"question",id:"3h0Sdf",label:"Recognize cluster headaches, and choose the most appropriate acute treatment.",children:[]},{type:"question",id:"fw0kRR",label:"Recognize cluster headache.",children:[]},{type:"question",id:"bTaH6P",label:"Recognize cluster headache.",children:[]},{type:"question",id:"7ga49P",label:"Recognize cluster headache, and choose the most appropriate pharmacotherapy for acute relief.",children:[]}]},{type:"article",id:"ef0xO2/ii0Jrf",label:"Trigeminal neuralgia",children:[{type:"question",id:"Ph0WVf",label:"Recognize trigeminal neuralgia, and choose the most appropriate initial pharmacotherapy.",children:[]},{type:"question",id:"5A0i4i",label:"Recognize trigeminal neuralgia.",children:[]},{type:"question",id:"AgaRBP",label:"Recognize trigeminal neuralgia, and choose the most appropriate initial treatment.",children:[]}]},{type:"article",id:"ef0xO2/ji0_rf",label:"Degenerative disk disease",children:[{type:"question",id:"10a2UQ",label:"Recognize S1 radiculopathy, and recall its effect on reflexes.",children:[]},{type:"question",id:"jfa_NP",label:"Recognize lateral disk herniation, and recall the site for steroid injection to relieve radiculopathy.",children:[]}]},{type:"article",id:"ef0xO2/Pi0W7f",label:"Dissection of the carotid and the vertebral artery",children:[{type:"question",id:"KM0Upg",label:"Recognize carotid artery dissection, and choose the most appropriate antithrombotic therapy.",children:[]}]},{type:"article",id:"ef0xO2/li0v7f",label:"Polycystic kidney disease",children:[{type:"question",id:"SWaykj",label:"Recognize autosomal dominant polycystic kidney disease, and recall its complications.",children:[]}]},{type:"article",id:"ef0xO2/QQ0uDf",label:"Thoracic outlet syndrome",children:[{type:"question",id:"Q8aumm",label:"Recognize neurogenic thoracic outlet syndrome, and choose the most appropriate initial management.",children:[]}]},{type:"article",id:"ef0xO2/kQ0mwf",label:"Torticollis",children:[{type:"question",id:"C60qMS",label:"Recognize congenital torticollis, and choose the most appropriate initial management.",children:[]}]},{type:"article",id:"ef0xO2/AQ0RAf",label:"Metal toxicity",children:[{type:"question",id:"8NaO1O",label:"Recognize mercury poisoning, and recall its treatment.",children:[]}]},{type:"article",id:"ef0xO2/-Q0DAf",label:"Work-related conditions",children:[{type:"question",id:"Fz0gui",label:"Recognize noise-induced hearing loss due to destruction of the organ of Corti.",children:[]},{type:"question",id:"KKaUhl",label:"Recognize noise-induced sensorineural hearing loss.",children:[]}]},{type:"article",id:"ef0xO2/Oj0I0T",label:"Pituitary adenoma",children:[{type:"question",id:"L3awQ4",label:"Recognize the clinical presentation of a pituitary adenoma, and recall its associated cellular origin.",children:[]}]},{type:"article",id:"ef0xO2/mj0VaT",label:"Otitis externa",children:[{type:"question",id:"3N0Sag",label:"Recognize otitis externa, and recall its most common pathogen.",children:[]},{type:"question",id:"GgaB9P",label:"Recognize otitis externa, and recall its most common causal pathogen.",children:[]},{type:"question",id:"Nqa-Al",label:"Recognize prevention strategies for recurrent otitis externa, and choose the most appropriate recommendation after swimming activities.",children:[]},{type:"question",id:"j7a_lN",label:"Recognize acute otitis externa, and choose the most appropriate topical therapy.",children:[]}]},{type:"article",id:"ef0xO2/5j0iaT",label:"Otitis media with effusion",children:[{type:"question",id:"On0Itg",label:"Recognize otitis media with effusion, and choose the most appropriate next step in management.",children:[]}]},{type:"article",id:"ef0xO2/Mj0MaT",label:"Acute otitis media",children:[{type:"question",id:"Pi0W7f",label:"Recognize acute mastoiditis with potential intracranial complications, and choose the most appropriate diagnostic test.",children:[]},{type:"question",id:"Mi0MHf",label:"Choose the most appropriate 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cancer.",children:[]},{type:"question",id:"GL0B_g",label:"Recognize brain metastasis, and choose the most appropriate next step in management.",children:[]},{type:"question",id:"EL08zg",label:"Recognize a pilocytic astrocytoma.",children:[]},{type:"question",id:"Zx0ZER",label:"Recognize hemangioblastoma associated with von Hippel-Lindau disease.",children:[]},{type:"question",id:"j1a_gj",label:"Recognize craniopharyngioma, and recall its origin.",children:[]},{type:"question",id:"g3aF34",label:"Recognize vestibular schwannoma, and recall its histopathological features.",children:[]},{type:"question",id:"43a3i4",label:"Recall the histopathological findings and typical location of a craniopharyngioma.",children:[]},{type:"question",id:"l3avi4",label:"Recognize pilocytic astrocytoma and its association with Rosenthal fibers.",children:[]},{type:"question",id:"_3a5O4",label:"Recognize glioblastoma multiforme, and recall its microscopic features.",children:[]},{type:"question",id:"A4aRNk",label:"Recognize medulloblastoma and its association with Homer Wright rosettes.",children:[]},{type:"question",id:"POaWsk",label:"Recognize brain metastases, and recall their common primary origins.",children:[]},{type:"question",id:"r8afLm",label:"Recognize glioblastoma multiforme (grade IV astrocytoma).",children:[]}]},{type:"article",id:"ef0xO2/G50Blg",label:"Orbital disorders",children:[{type:"question",id:"Wt0Pc3",label:"Recognize signs specific to orbital cellulitis, and choose the strongest indication for administering intravenous antibiotics.",children:[]},{type:"question",id:"ewax35",label:"Recognize preseptal cellulitis.",children:[]}]},{type:"article",id:"ef0xO2/y50d5g",label:"Basics of human genetics",children:[{type:"question",id:"O2aI3P",label:"Recognize Leber hereditary optic neuropathy, and recall its mitochondrial inheritance pattern.",children:[]}]},{type:"article",id:"ef0xO2/bM0HMg",label:"Subclavian steal syndrome",children:[{type:"question",id:"uM0pqg",label:"Recognize subclavian steal syndrome.",children:[]}]},{type:"article",id:"ef0xO2/4M03Kg",label:"Endophthalmitis",children:[{type:"question",id:"SDayd5",label:"Recognize acute postoperative endophthalmitis, and choose the most appropriate management.",children:[]}]},{type:"article",id:"ef0xO2/8M0Oqg",label:"Chloroquine and hydroxychloroquine",children:[{type:"question",id:"YQ0nuf",label:"Recognize chloroquine retinopathy.",children:[]}]},{type:"article",id:"ef0xO2/EM08qg",label:"Hydrocephalus",children:[{type:"question",id:"Zn0Z7g",label:"Recognize normal pressure hydrocephalus.",children:[]},{type:"question",id:"tn0XEg",label:"Recognize normal pressure hydrocephalus, and recall its pathophysiology.",children:[]},{type:"question",id:"Fn0gEg",label:"Recognize hydrocephalus in an infant, and choose the initial neuroimaging modality.",children:[]},{type:"question",id:"8n0OEg",label:"Recognize communicating hydrocephalus, and choose the most appropriate treatment.",children:[]},{type:"question",id:"eVaxtj",label:"Recognize normal pressure hydrocephalus, and choose the definitive treatment to improve the patient's condition.",children:[]},{type:"question",id:"xTaEGP",label:"Recognize normal pressure hydrocephalus.",children:[]},{type:"question",id:"5haie4",label:"Recognize congenital toxoplasmosis, and recall its neurological manifestations.",children:[]},{type:"question",id:"7ia4G4",label:"Recognize normal pressure hydrocephalus, and recall its clinical triad.",children:[]},{type:"question",id:"enaxHO",label:"Recognize cortical atrophy associated with dementia.",children:[]},{type:"question",id:"L6awll",label:"Recognize communicating hydrocephalus, and recall its association with meningitis complications.",children:[]},{type:"question",id:"PFaWRm",label:"Recognize normal pressure hydrocephalus, and choose the most appropriate diagnostic test.",children:[]}]},{type:"article",id:"ef0xO2/Sn0ysg",label:"Bacteria overview",children:[{type:"question",id:"gRaFm4",label:"Recognize neonatal meningitis, and recall the virulence factors of Escherichia coli.",children:[]},{type:"question",id:"uRapK4",label:"Recognize Neisseria meningitidis meningitis, and recall its initial virulence factor for infection.",children:[]},{type:"question",id:"2kaTMk",label:"Recognize malignant otitis externa, and recall the mechanism of Pseudomonas exotoxin A.",children:[]},{type:"question",id:"UNab0O",label:"Recognize bacterial meningitis, and recall the growth requirements of Haemophilus influenzae.",children:[]}]},{type:"article",id:"ef0xO2/nL07yg",label:"Botulism",children:[{type:"question",id:"kg0mv2",label:"Recognize infant botulism, and choose the most appropriate initial treatment.",children:[]},{type:"question",id:"6M0jpg",label:"Recognize foodborne botulism, and recall its mechanism of action.",children:[]},{type:"question",id:"kPamUk",label:"Recognize botulism, and recall its cause.",children:[]},{type:"question",id:"WLaP9O",label:"Recognize infant botulism, and recall the mechanism of action of the causal toxin.",children:[]}]},{type:"article",id:"ef0xO2/HL0K_g",label:"Elevated intracranial pressure and brain herniation",children:[{type:"question",id:"mN0Vbg",label:"Choose the most appropriate intervention to reduce cerebral blood flow in the context of intracranial pressure management.",children:[]},{type:"question",id:"MN0Mbg",label:"Recognize Cushing's triad, and recall its association with elevated intracranial pressure.",children:[]},{type:"question",id:"nN07bg",label:"Recognize uncal herniation, and recall its early neurological sequelae.",children:[]},{type:"question",id:"GM0BJg",label:"Recognize subfalcine herniation.",children:[]},{type:"question",id:"0iaeJ4",label:"Recognize transtentorial uncal herniation, and recall the associated false localizing signs.",children:[]},{type:"question",id:"tiaXt4",label:"Recognize subfalcine herniation.",children:[]},{type:"question",id:"rOafFk",label:"Choose the intervention to decrease intracranial pressure in a patient with cerebral edema post-stroke.",children:[]},{type:"question",id:"Tna6sO",label:"Recognize transtentorial uncal herniation, and recall the cranial nerve most likely to be injured.",children:[]},{type:"question",id:"lKavgl",label:"Recognize HSV encephalitis, and recall the pathologic mechanism underlying vasogenic edema.",children:[]}]},{type:"article",id:"ef0xO2/tL0Xzg",label:"Mitral valve stenosis",children:[{type:"question",id:"DMa1IO",label:"Recognize extrinsic impingement of the recurrent laryngeal nerve.",children:[]}]},{type:"article",id:"ef0xO2/1o02aS",label:"HIV-associated conditions",children:[{type:"question",id:"og00w2",label:"Recognize cytomegalovirus retinitis in HIV/AIDS.",children:[]},{type:"question",id:"Gi0BGf",label:"Recognize primary CNS lymphoma in an HIV patient.",children:[]},{type:"question",id:"0Q0euf",label:"Choose the most appropriate treatment for primary CNS lymphoma.",children:[]},{type:"question",id:"5SaiZ4",label:"Recognize primary cerebral lymphoma in HIV patients.",children:[]}]},{type:"article",id:"ef0xO2/ko0mXS",label:"Carotid artery stenosis",children:[{type:"question",id:"sj0tbT",label:"Recognize symptomatic carotid artery stenosis, and choose the initial diagnostic test.",children:[]},{type:"question",id:"sM0tJg",label:"Recognize a transient ischemic attack (TIA), and choose the most appropriate secondary prevention strategy.",children:[]}]},{type:"article",id:"ef0xO2/5o0icS",label:"Cerebral palsy",children:[{type:"question",id:"so0tWS",label:"Recognize spastic cerebral palsy, and recall its strongest risk factor.",children:[]}]},{type:"article",id:"ef0xO2/Lo0wcS",label:"The cell",children:[{type:"question",id:"E3a844",label:"Recognize the chemoreceptor trigger zone, and recall the proteins that compose tight junctions.",children:[]}]},{type:"article",id:"ef0xO2/qo0C1S",label:"Signal transduction",children:[{type:"question",id:"rMafJO",label:"Recall the effect of acetylcholine on endothelial nitric oxide release.",children:[]}]},{type:"article",id:"ef0xO2/Fo0gdS",label:"Preterm labor and birth",children:[{type:"question",id:"Wo0PaS",label:"Recognize intraventricular hemorrhage in preterm infants.",children:[]},{type:"question",id:"zgarBP",label:"Recognize germinal matrix hemorrhage in preterm infants.",children:[]}]},{type:"article",id:"ef0xO2/uo0pdS",label:"Basics of embryology",children:[{type:"question",id:"ULabCO",label:"Recognize holoprosencephaly, and recall its embryological origin.",children:[]}]},{type:"article",id:"ef0xO2/vo0AdS",label:"Embryogenesis",children:[{type:"question",id:"TTa6JP",label:"Recognize facial nerve palsy, and recall the muscles it innervates.",children:[]},{type:"question",id:"a3aQS4",label:"Recognize neurofibromatosis type 2, and recall the origin of Schwann cells.",children:[]}]},{type:"article",id:"ef0xO2/9o0NVS",label:"Resting potentials and action potentials",children:[{type:"question",id:"3daSpj",label:"Recognize tetrodotoxin poisoning, and recall its mechanism of action.",children:[]},{type:"question",id:"Nna-tO",label:"Recognize Guillain-Barr\xe9 syndrome, and recall the effects of remyelination on neuronal properties.",children:[]}]},{type:"article",id:"ef0xO2/WK0P2S",label:"The cerebral cortex, meninges, basal ganglia, and ventricular system",children:[{type:"question",id:"6cajWj",label:"Recall the regions of the body corresponding to different areas of the motor homunculus.",children:[]},{type:"question",id:"AeaRYP",label:"Recall the function of the superior parietal lobule in stereognosis.",children:[]},{type:"question",id:"rSafa4",label:"Recognize Broca aphasia, and recall neuroanatomy of the cerebral cortex.",children:[]},{type:"question",id:"yPadhk",label:"Recognize schizophrenia, and recall the dopaminergic pathway targeted by antipsychotics.",children:[]},{type:"question",id:"NMa-KO",label:"Recall neuroanatomy of the basal ganglia.",children:[]},{type:"question",id:"S6ay4l",label:"Recognize Wilson disease, and recall neuroanatomy of the basal ganglia.",children:[]},{type:"question",id:"YpanLl",label:"Recognize prosopagnosia, and recall the brain region typically affected.",children:[]},{type:"question",id:"kramhN",label:"Recognize noncommunicating hydrocephalus, and recall the ventricular system's embryologic origins.",children:[]},{type:"question",id:"4ua3rm",label:"Recognize cerebral contrecoup injury, and recall its behavioral sequelae.",children:[]}]},{type:"article",id:"ef0xO2/FK0gRS",label:"Amino acids",children:[{type:"question",id:"7da4rj",label:"Recognize a urea cycle disorder, and recall the role of glutamine in hyperammonemia.",children:[]}]},{type:"article",id:"ef0xO2/vK0ARS",label:"Skull",children:[{type:"question",id:"xSaEb4",label:"Recognize acute epidural hematoma, and recall the associated vascular anatomy.",children:[]}]},{type:"article",id:"ef0xO2/b60HjS",label:"Head and neck region",children:[{type:"question",id:"DRa164",label:"Recognize phrenic nerve compression, and recall its sensory innervation.",children:[]}]},{type:"article",id:"ef0xO2/e60xPS",label:"Nose and sinuses",children:[{type:"question",id:"MQaM94",label:"Recall the sensory pathway that bypasses the thalamus.",children:[]}]},{type:"article",id:"ef0xO2/T6064S",label:"Larynx",children:[{type:"question",id:"qz0CFi",label:"Recall the anatomy and function of the superior laryngeal nerve.",children:[]}]},{type:"article",id:"ef0xO2/560ilS",label:"Autonomic nervous system",children:[{type:"question",id:"ukappk",label:"Recall the types of acetylcholine receptors, and recall their structural similarities.",children:[]}]},{type:"article",id:"ef0xO2/p60LNS",label:"The leg, ankle, and foot",children:[{type:"question",id:"gTaFJP",label:"Recall the sensory and motor innervation of the deep peroneal nerve.",children:[]}]},{type:"article",id:"ef0xO2/G60BmS",label:"Spinal cord tracts and reflexes",children:[{type:"question",id:"NPa-Uk",label:"Recall neuroanatomy of ascending sensory pathways in the spinal cord.",children:[]},{type:"question",id:"zbarwQ",label:"Recognize lower motor neuron damage, and recall neuroanatomy of the spinal cord.",children:[]},{type:"question",id:"5maiTO",label:"Recognize vitamin B12 deficiency neuropathy, and recall its effects on proprioception and vibratory sensation.",children:[]},{type:"question",id:"ynadDO",label:"Recognize the anatomical features of spinal cord cross-sections.",children:[]}]},{type:"article",id:"ef0xO2/A60RnS",label:"Pelvis and hip joint",children:[{type:"question",id:"YVanGj",label:"Recall the sensory and motor innervation of the pudendal nerve.",children:[]},{type:"question",id:"DQa1y4",label:"Recognize pudendal nerve injury, and recall its effects on reflexes.",children:[]}]},{type:"article",id:"ef0xO2/-60DnS",label:"Diencephalon",children:[{type:"question",id:"-eaDYP",label:"Recall the role of the suprachiasmatic nucleus in sleep regulation.",children:[]},{type:"question",id:"0UaebP",label:"Recognize secondary hypothermia due to central nervous system lesions, and recall the role of the preoptic nucleus in thermoregulation.",children:[]},{type:"question",id:"oSa004",label:"Recall the function of the lateral nucleus of the hypothalamus, and recall the effects of its inhibition.",children:[]}]},{type:"article",id:"ef0xO2/Yp0nLS",label:"Cerebrovascular system",children:[{type:"question",id:"wSahb4",label:"Recognize anterior cerebral artery stroke, and recall the anatomy of the circle of Willis.",children:[]}]},{type:"article",id:"ef0xO2/cp0aoS",label:"Eye and orbit",children:[{type:"question",id:"Nwa-Q5",label:"Recognize myopia, and choose the appropriate corrective lenses.",children:[]}]},{type:"article",id:"ef0xO2/hp0c6S",label:"Aging changes",children:[{type:"question",id:"ZsaZtN",label:"Recognize abnormal neurologic examination findings, and recall conditions that necessitate immediate investigation.",children:[]}]},{type:"article",id:"ef0xO2/3p0S6S",label:"Forearm, wrist, and hand",children:[{type:"question",id:"vTaAsP",label:"Recognize a ganglion cyst causing carpal tunnel syndrome, and recall the structures passing through the carpal tunnel.",children:[]}]},{type:"article",id:"ef0xO2/Qp0u6S",label:"Glycolysis and gluconeogenesis",children:[{type:"question",id:"kdamJj",label:"Recognize ethanol intoxication, and recall its effect on pyruvate dehydrogenase activity.",children:[]}]},{type:"article",id:"ef0xO2/lp0vpS",label:"Nerve tissue, synapses, and neurotransmitters",children:[{type:"question",id:"BSazb4",label:"Recall the function of SSRIs, and recall the primary site of serotonin production in the brain.",children:[]},{type:"question",id:"mMaV6O",label:"Recall the events that trigger neurotransmitter release from presynaptic terminals.",children:[]},{type:"question",id:"GMaBJO",label:"Recall the process of reactive gliosis in the CNS and the predominant cell type involved.",children:[]},{type:"question",id:"Fpagrl",label:"Recall the role of N-methyl-D-aspartate receptors in synaptic remodeling and addiction.",children:[]}]},{type:"article",id:"ef0xO2/iJ0JFS",label:"Ischemic stroke",children:[{type:"question",id:"-n0DDg",label:"Recognize symptoms of embolic stroke, and recall the characteristic ECG findings of its common cause.",children:[]},{type:"question",id:"6L0jAg",label:"Recognize acute ischemic stroke, and choose the most appropriate acute management.",children:[]},{type:"question",id:"eo0xaS",label:"Recognize lipohyalinosis of lenticulostriate arteries as a cause of pure motor stroke.",children:[]},{type:"question",id:"jha_d4",label:"Recognize lipohyalinosis of penetrating vessels as a cause of lacunar infarct.",children:[]},{type:"question",id:"9iaNF4",label:"Recognize systemic hypotension as a cause of watershed infarcts.",children:[]},{type:"question",id:"OQaIw4",label:"Recognize anterograde amnesia, and recall the brain structure involved in short-term memory.",children:[]},{type:"question",id:"oQa0C4",label:"Recognize the presentation of an acute ischemic stroke, and choose the appropriate thrombolytic therapy.",children:[]},{type:"question",id:"MMaM6O",label:"Recall the immunophenotype and function of microglia in the brain.",children:[]},{type:"question",id:"4na3tO",label:"Recall the timeline of histological changes after ischemic brain injury.",children:[]},{type:"question",id:"knamtO",label:"Recognize the timeline of ischemic stroke, and recall the associated histopathologic changes.",children:[]}]},{type:"article",id:"ef0xO2/Uq0bBS",label:"Hypertensive crises",children:[{type:"question",id:"vn0AEg",label:"Recognize a hypertensive 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compression.",children:[]},{type:"question",id:"PL0WBg",label:"Recognize compressive myelopathy due to metastases, and choose the most appropriate initial management.",children:[]},{type:"question",id:"vZaAWQ",label:"Recognize cauda equina syndrome.",children:[]}]},{type:"article",id:"ef0xO2/9q0N0h",label:"Spinal infections",children:[{type:"question",id:"Un0bsg",label:"Recognize spinal epidural abscess, and choose the most appropriate diagnostic test.",children:[]}]},{type:"article",id:"ef0xO2/II0YVh",label:"Morton neuroma",children:[{type:"question",id:"4l03CT",label:"Recognize intermetatarsal neuroma.",children:[]}]},{type:"article",id:"ef0xO2/6r0jRh",label:"Transient ischemic attack",children:[{type:"question",id:"uEapxm",label:"Recognize a transient ischemic attack (TIA), and choose the most appropriate next step in management.",children:[]}]},{type:"article",id:"ef0xO2/b70H4h",label:"Brainstem",children:[{type:"question",id:"RralSN",label:"Recognize medial medullary syndrome, and recall neuroanatomy of the medulla oblongata.",children:[]}]},{type:"article",id:"ef0xO2/fH0kph",label:"Vertigo",children:[{type:"question",id:"Rwali5",label:"Recognize acute vestibular syndrome (AVS), and choose the most appropriate next step in management.",children:[]}]},{type:"article",id:"ef0xO2/KH0Urh",label:"Neuroleptic malignant syndrome",children:[{type:"question",id:"4M03Kg",label:"Recognize neuroleptic malignant syndrome, and recall drugs that can cause it.",children:[]},{type:"question",id:"Mn0MFg",label:"Recognize neuroleptic malignant syndrome.",children:[]},{type:"question",id:"qn0C8g",label:"Recognize neuroleptic malignant syndrome, and choose the most appropriate initial pharmacotherapy.",children:[]},{type:"question",id:"wZahdQ",label:"Recognize neuroleptic malignant syndrome, and recall the mechanism of action of dantrolene.",children:[]},{type:"question",id:"5TairP",label:"Recognize neuroleptic malignant syndrome, and recall drugs that can cause it.",children:[]}]},{type:"article",id:"ef0xO2/CH0qsh",label:"Progressive multifocal leukoencephalopathy",children:[{type:"question",id:"u2apjP",label:"Recognize progressive multifocal leukoencephalopathy, and recall its risk factors.",children:[]},{type:"question",id:"eFaxSm",label:"Recognize progressive multifocal leukoencephalopathy.",children:[]}]},{type:"article",id:"ef0xO2/bs0Hth",label:"Drug reaction with eosinophilia and systemic symptoms",children:[{type:"question",id:"NUa-WP",label:"Recognize DRESS syndrome, and recall its diagnostic findings.",children:[]}]},{type:"article",id:"ef0xO2/Ss0y8h",label:"Opioid withdrawal",children:[{type:"question",id:"xH0Esh",label:"Recognize neonatal abstinence syndrome, and choose the most appropriate pharmacological treatment.",children:[]},{type:"question",id:"PUaWWP",label:"Recognize neonatal abstinence syndrome, and recall its associated maternal drug use.",children:[]}]},{type:"article",id:"ef0xO2/gG0FAh",label:"Malignant otitis 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recall its association with urinary retention.",children:[]},{type:"question",id:"WiaPq4",label:"Recognize diabetic neuropathy, and recall its microvascular pathogenesis.",children:[]}]},{type:"article",id:"ef0xO2/7t04U3",label:"Bacterial conjunctivitis",children:[{type:"question",id:"kQ0mwf",label:"Choose the most appropriate pharmacotherapy for acute bacterial conjunctivitis.",children:[]}]},{type:"article",id:"ef0xO2/Ht0KU3",label:"Viral conjunctivitis",children:[{type:"question",id:"r30fPf",label:"Recognize herpes simplex virus conjunctivitis in patients with atopic dermatitis.",children:[]}]},{type:"article",id:"ef0xO2/st0tU3",label:"Noninfectious conjunctivitis",children:[{type:"question",id:"OQ0Iwf",label:"Recognize seasonal allergic conjunctivitis, and choose the most appropriate treatment.",children:[]}]},{type:"article",id:"ef0xO2/zt0rT3",label:"Cerumen impaction",children:[{type:"question",id:"L9YwLr",label:"Choose the most appropriate management for symptomatic cerumen impaction.",children:[]}]},{type:"article",id:"ef0xO2/ZF0Zg3",label:"Serotonin syndrome",children:[{type:"question",id:"CZaqdQ",label:"Recognize serotonin syndrome, and recall serotonergic drugs.",children:[]},{type:"question",id:"jSa_zP",label:"Recognize serotonin syndrome, and choose the most appropriate antidote.",children:[]}]},{type:"article",id:"ef0xO2/nF07i3",label:"Stimulant intoxication and withdrawal",children:[{type:"question",id:"hH0cJh",label:"Recognize cocaine-induced stroke, and recall its pathophysiology.",children:[]},{type:"question",id:"hlac9k",label:"Recognize amphetamine intoxication, and recall its precursor in synthesis.",children:[]}]},{type:"article",id:"ef0xO2/qF0CQ3",label:"Psychiatric drug poisoning",children:[{type:"question",id:"no07cS",label:"Recognize acute lithium toxicity, and choose the most appropriate treatment.",children:[]},{type:"question",id:"ztarTm",label:"Recognize tricyclic antidepressant overdose, and choose the appropriate antidote for cardiac toxicity.",children:[]},{type:"question",id:"-taDTm",label:"Recognize tricyclic antidepressant overdose, and choose the most appropriate initial diagnostic test.",children:[]}]},{type:"article",id:"ef0xO2/EF08P3",label:"Overview of fungal infections",children:[{type:"question",id:"o900oR",label:"Recognize rhino-orbital-cerebral mucormycosis, and recall its common causal organism.",children:[]}]},{type:"article",id:"ef0xO2/CF0q43",label:"Ear injuries",children:[{type:"question",id:"PvaWZ5",label:"Recognize an auricular hematoma, and choose the most appropriate initial step in management.",children:[]}]},{type:"article",id:"ef0xO2/Q80um3",label:"Sedative-hypnotic drug overdose",children:[{type:"question",id:"Jg0sw2",label:"Recognize benzodiazepine toxicity, and choose the appropriate antidote.",children:[]},{type:"question",id:"3s0Suh",label:"Recognize benzodiazepine withdrawal as a cause of seizure following flumazenil administration.",children:[]},{type:"question",id:"Bjazck",label:"Recognize benzodiazepine overdose, and recall the receptor targeted by its antidote.",children:[]}]},{type:"article",id:"ef0xO2/I80YL3",label:"Cholinergic poisoning",children:[{type:"question",id:"Zy0Zdi",label:"Recognize organophosphate poisoning, and recall its antidote mechanism of action.",children:[]},{type:"question",id:"m3aVQ4",label:"Recognize cholinergic crisis, and choose the appropriate pharmacotherapy to reverse neuromuscular dysfunction.",children:[]},{type:"question",id:"q3aCj4",label:"Choose the most appropriate pharmacotherapy to reverse cholinergic toxicity.",children:[]}]},{type:"article",id:"ef0xO2/-80D63",label:"Acute and posttraumatic stress disorders",children:[{type:"question",id:"4H03qh",label:"Recognize acute stress disorder.",children:[]}]}]},{type:"system",id:"L0/2f0Tl2",label:"Pregnancy, Childbirth & the Puerperium",children:[{type:"article",id:"2f0Tl2/ef0xO2",label:"Tetanus",children:[{type:"question",id:"bh0Hcf",label:"Recognize neonatal tetanus, and recall its causal organism.",children:[]}]},{type:"article",id:"2f0Tl2/Nf0-m2",label:"Listeriosis",children:[{type:"question",id:"v4aAOk",label:"Recognize listeriosis in pregnancy, and recall its transmission through contaminated food.",children:[]}]},{type:"article",id:"2f0Tl2/mf0V52",label:"Human immunodeficiency virus infection",children:[{type:"question",id:"Wp0PoS",label:"Choose the management strategy to reduce vertical transmission of HIV in pregnancy.",children:[]},{type:"question",id:"dp0ooS",label:"Choose the most appropriate postexposure prophylaxis for a newborn born to a mother with HIV.",children:[]}]},{type:"article",id:"2f0Tl2/rf0fn2",label:"Candidiasis",children:[{type:"question",id:"ACaRu5",label:"Choose the most appropriate management for neonatal oral thrush and mammary candidiasis.",children:[]}]},{type:"article",id:"2f0Tl2/tT0Xs2",label:"Thalassemia",children:[{type:"question",id:"Mr0M3h",label:"Recognize microcytic hypochromic anemia with normal iron studies, and choose the most appropriate diagnostic test.",children:[]},{type:"question",id:"Svayzm",label:"Recognize fetal hypoxia due to alpha thalassemia major.",children:[]},{type:"question",id:"rxafB5",label:"Choose the most appropriate fetal testing method for a pregnancy at risk for thalassemia.",children:[]}]},{type:"article",id:"2f0Tl2/-T0Dt2",label:"Hypopituitarism",children:[{type:"question",id:"BA0zNi",label:"Recognize Sheehan syndrome, and recall its hormonal findings.",children:[]}]},{type:"article",id:"2f0Tl2/cg0a82",label:"Hypothyroidism",children:[{type:"question",id:"HzaK8M",label:"Choose the most appropriate management of hypothyroidism during pregnancy.",children:[]}]},{type:"article",id:"2f0Tl2/OS0I-2",label:"Hepatitis B",children:[{type:"question",id:"akaQmk",label:"Recognize evidence of successful hepatitis B vaccination, and choose the appropriate delivery plan for the patient.",children:[]}]},{type:"article",id:"2f0Tl2/lS0v-2",label:"Hepatitis C",children:[{type:"question",id:"oi00sf",label:"Choose the most appropriate vaccination for a pregnant patient with chronic hepatitis C infection.",children:[]}]},{type:"article",id:"2f0Tl2/Ch0qTf",label:"Congenital diaphragmatic hernias",children:[{type:"question",id:"bPaHWk",label:"Recognize a bronchogenic cyst, and recall its embryological origin.",children:[]}]},{type:"article",id:"2f0Tl2/hR0c5f",label:"Antiphospholipid syndrome",children:[{type:"question",id:"Y70n4h",label:"Recognize placental thrombosis secondary to antiphospholipid syndrome.",children:[]},{type:"question",id:"880Oo3",label:"Recognize antiphospholipid syndrome in pregnancy, and choose the appropriate anticoagulation therapy.",children:[]}]},{type:"article",id:"2f0Tl2/sR0tof",label:"Carpal tunnel syndrome",children:[{type:"question",id:"VdaGKj",label:"Recognize carpal tunnel syndrome, and recall its potential complications.",children:[]}]},{type:"article",id:"2f0Tl2/vR0AKf",label:"Inborn errors of metabolism",children:[{type:"question",id:"eT0xp2",label:"Recognize malignant phenylketonuria (PKU), and choose the appropriate supplementation to prevent further complications.",children:[]},{type:"question",id:"rL0f_g",label:"Recognize phenylketonuria (PKU), and choose the appropriate dietary intervention to prevent its symptoms.",children:[]}]},{type:"article",id:"2f0Tl2/hi0crf",label:"Migraine",children:[{type:"question",id:"2uaTqm",label:"Choose the most appropriate pharmacotherapy for migraine in pregnancy.",children:[]}]},{type:"article",id:"2f0Tl2/7i04Gf",label:"Urinary tract infections",children:[{type:"question",id:"oj00YT",label:"Choose the most appropriate antibiotic for asymptomatic bacteriuria during pregnancy.",children:[]},{type:"question",id:"aEaQ8m",label:"Recognize the management of asymptomatic bacteriuria in pregnancy, and choose the most appropriate next step in management.",children:[]}]},{type:"article",id:"2f0Tl2/kQ0mwf",label:"Torticollis",children:[{type:"question",id:"O0aITQ",label:"Recognize congenital torticollis, and recall its predisposing factors.",children:[]}]},{type:"article",id:"2f0Tl2/PP0WUT",label:"Major depressive disorder",children:[{type:"question",id:"utap2m",label:"Recognize the symptoms of postpartum blues, and choose the appropriate follow-up care.",children:[]}]},{type:"article",id:"2f0Tl2/pP0LfT",label:"Schizophrenia",children:[{type:"question",id:"6s0jDh",label:"Recognize treatment-resistant schizophrenia, and choose the most appropriate antipsychotic therapy.",children:[]}]},{type:"article",id:"2f0Tl2/a40Q3T",label:"The newborn infant",children:[{type:"question",id:"KK0UhS",label:"Recognize normal neonatal weight loss, and choose the most appropriate management for a healthy exclusively breastfed newborn.",children:[]},{type:"question",id:"6K0jhS",label:"Recognize the need for neonatal resuscitation, and choose the initial resuscitation step.",children:[]},{type:"question",id:"JK0shS",label:"Recognize intrauterine hypoxia as a cause of neonatal polycythemia.",children:[]},{type:"question",id:"qK0ChS",label:"Recognize the effects of maternal estrogen exposure in a neonate, and choose the most appropriate management.",children:[]}]},{type:"article",id:"2f0Tl2/1402RT",label:"Tall stature and abnormally rapid growth",children:[{type:"question",id:"vK0ARS",label:"Recognize the signs of hypoglycemia in neonates with Beckwith-Wiedemann syndrome, and choose the most appropriate intervention.",children:[]}]},{type:"article",id:"2f0Tl2/d40oRT",label:"Congenital TORCH infections",children:[{type:"question",id:"JS0s0f",label:"Recognize the clinical presentation of rubella, and choose the appropriate management for a pregnant patient beyond the first trimester.",children:[]},{type:"question",id:"Xi09Jf",label:"Recognize neonatal herpes simplex virus infection, and choose the most appropriate pharmacotherapy.",children:[]},{type:"question",id:"ci0aqf",label:"Recognize the risk of varicella infection in a pregnant woman without immunity, and choose the most appropriate prophylactic treatment.",children:[]},{type:"question",id:"di0oqf",label:"Recognize active genital herpes in labor, and choose the appropriate delivery method and antiviral therapy.",children:[]},{type:"question",id:"nP072T",label:"Recognize congenital toxoplasmosis.",children:[]},{type:"question",id:"LP0w2T",label:"Recognize congenital rubella infection.",children:[]},{type:"question",id:"Go0BWS",label:"Recognize congenital cytomegalovirus infection.",children:[]},{type:"question",id:"Fr0gQh",label:"Recognize hydrops fetalis, and recall its association with Parvovirus B19 infection.",children:[]},{type:"question",id:"o0a0SQ",label:"Recognize congenital Toxoplasma gondii infection.",children:[]},{type:"question",id:"dbaosQ",label:"Recognize congenital rubella infection.",children:[]},{type:"question",id:"ZtaZXm",label:"Recognize early-onset neonatal listeriosis, and recall its maternal risk factors.",children:[]},{type:"question",id:"GDaBf5",label:"Recognize early congenital syphilis, and choose the most appropriate initial diagnostic test.",children:[]}]},{type:"article",id:"2f0Tl2/V40GRT",label:"Teratogenesis",children:[{type:"question",id:"-VaDCj",label:"Recall the complications of cocaine use during pregnancy.",children:[]}]},{type:"article",id:"2f0Tl2/e40xRT",label:"Chromosomal aberrations",children:[{type:"question",id:"wo0hVS",label:"Recognize Edwards syndrome (trisomy 18), and recall its associated cardiac malformation.",children:[]},{type:"question",id:"PK0WgS",label:"Recognize trisomy 18 (Edwards syndrome).",children:[]},{type:"question",id:"80aO3Q",label:"Recognize trisomy 18 (Edwards syndrome).",children:[]}]},{type:"article",id:"2f0Tl2/U40biT",label:"Down syndrome",children:[{type:"question",id:"bXaH9Q",label:"Recognize fetal trisomy 21, and recall its associated quadruple marker test findings.",children:[]}]},{type:"article",id:"2f0Tl2/240TiT",label:"Rare inherited syndromes",children:[{type:"question",id:"To06YS",label:"Recognize fragile X syndrome, and recall its associated cardiac complications.",children:[]}]},{type:"article",id:"2f0Tl2/T406iT",label:"Sudden infant death syndrome",children:[{type:"question",id:"2S0T_2",label:"Choose the most effective step to prevent sudden infant death syndrome.",children:[]},{type:"question",id:"WEaPum",label:"Recall risk factors for sudden infant death syndrome (SIDS).",children:[]},{type:"question",id:"vxaAy5",label:"Recognize a low-risk brief resolved unexplained event (BRUE), and choose the most appropriate next step in evaluation.",children:[]}]},{type:"article",id:"2f0Tl2/S40yiT",label:"Birth traumas",children:[{type:"question",id:"5o0icS",label:"Recognize cephalohematoma in a newborn.",children:[]},{type:"question",id:"i60JkS",label:"Recognize neonatal clavicle fracture, and choose the most appropriate initial management.",children:[]}]},{type:"article",id:"2f0Tl2/340SQT",label:"Neonatal respiratory distress syndrome",children:[{type:"question",id:"f60k4S",label:"Recognize transient tachypnea of the newborn, and choose the initial supportive care measure.",children:[]},{type:"question",id:"j60_kS",label:"Recognize respiratory distress syndrome in preterm newborns.",children:[]},{type:"question",id:"LI0wWh",label:"Recognize postterm pregnancy, and recall its neonatal complications.",children:[]},{type:"question",id:"SMayLO",label:"Recognize neonatal respiratory distress syndrome (NRDS), and choose the appropriate antenatal medication to prevent it.",children:[]},{type:"question",id:"_ta5Tm",label:"Recognize meconium aspiration syndrome, and choose the most appropriate initial management.",children:[]}]},{type:"article",id:"2f0Tl2/R40lQT",label:"Neonatal jaundice",children:[{type:"question",id:"bK0HUS",label:"Recognize unconjugated hyperbilirubinemia in a newborn, and choose the first-line treatment.",children:[]},{type:"question",id:"vJ0ADS",label:"Recognize inadequate breastfeeding as a cause of neonatal jaundice.",children:[]},{type:"question",id:"CJ0qwS",label:"Recognize breastfeeding failure jaundice, and choose the most appropriate management to address dehydration and weight loss.",children:[]},{type:"question",id:"yJ0d9S",label:"Recognize breast milk jaundice.",children:[]},{type:"question",id:"JzasFM",label:"Recognize physiological neonatal jaundice.",children:[]}]},{type:"article",id:"2f0Tl2/i40JQT",label:"Hemolytic disease of the fetus and newborn",children:[{type:"question",id:"bi0HJf",label:"Choose the appropriate timing for anti-D antibody screening and administration of anti-D immunoglobulin in Rh-negative pregnant women.",children:[]},{type:"question",id:"rQ0fxf",label:"Recognize hemolytic disease of the newborn due to Rh incompatibility, and recall its risk factors.",children:[]},{type:"question",id:"vQ0ABf",label:"Recognize ABO incompatibility as a cause of hemolytic disease of the newborn.",children:[]},{type:"question",id:"W70Pkh",label:"Recognize fetomaternal hemorrhage in an Rh-negative mother, and choose the most appropriate test to quantify it.",children:[]},{type:"question",id:"cRaaN4",label:"Recognize ABO incompatibility in neonatal jaundice, and recall the role of maternal antibodies.",children:[]},{type:"question",id:"YianJ4",label:"Recognize hemolytic disease of the newborn due to Rh incompatibility, and recall its risk factors.",children:[]},{type:"question",id:"W4aPRk",label:"Choose the appropriate prophylactic treatment for Rh-negative pregnant women.",children:[]},{type:"question",id:"yuadFm",label:"Choose the appropriate management for Rh-negative women after spontaneous abortion.",children:[]}]},{type:"article",id:"2f0Tl2/Q40uQT",label:"Vitamin K deficiency bleeding of the newborn",children:[{type:"question",id:"UJ0btS",label:"Recall the importance of vitamin K prophylaxis in newborns.",children:[]}]},{type:"article",id:"2f0Tl2/4403jT",label:"Acyanotic congenital heart defects",children:[{type:"question",id:"Utab1m",label:"Recognize patent ductus arteriosus, and choose the most appropriate pharmacotherapy.",children:[]}]},{type:"article",id:"2f0Tl2/L40wPT",label:"Cystic fibrosis",children:[{type:"question",id:"0k0emT",label:"Recognize meconium ileus as a cause of bowel obstruction in a newborn, and choose the most appropriate initial management.",children:[]}]},{type:"article",id:"2f0Tl2/K40U4T",label:"Esophageal atresia",children:[{type:"question",id:"ieaJAj",label:"Recognize VACTERL association, and recall its pathogenesis.",children:[]}]},{type:"article",id:"2f0Tl2/p40L4T",label:"Congenital visceral malformations",children:[{type:"question",id:"8K0ORS",label:"Recognize gastroschisis as an isolated defect.",children:[]}]},{type:"article",id:"2f0Tl2/aO0QIT",label:"Ovarian cancer",children:[{type:"question",id:"guaFqm",label:"Recognize the source of progesterone in different stages of pregnancy, and choose the appropriate management after oophorectomy.",children:[]}]},{type:"article",id:"2f0Tl2/dO0orT",label:"Pregnancy",children:[{type:"question",id:"N0a-TQ",label:"Recognize the timeline of early pregnancy detection, and choose the most sensitive test for diagnosing pregnancy.",children:[]},{type:"question",id:"-aaDMQ",label:"Recall the physiological changes in pregnancy affecting renal function, and recall the cause of glucosuria in this context.",children:[]},{type:"question",id:"lVavuj",label:"Recognize increased intravascular volume during pregnancy exacerbating mitral stenosis.",children:[]},{type:"question",id:"1ra2TN",label:"Recall changes in maternal human chorionic 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toxicity.",children:[]},{type:"question",id:"cI0abh",label:"Recognize chronic hypertension in pregnancy.",children:[]},{type:"question",id:"HI0KVh",label:"Recognize chronic hypertension in pregnancy, and recall its fetal complications.",children:[]},{type:"question",id:"9I0NUh",label:"Recognize postpartum eclampsia, and choose the most appropriate anticonvulsive therapy.",children:[]},{type:"question",id:"I70YMh",label:"Recognize pulmonary edema as a complication of preeclampsia.",children:[]},{type:"question",id:"50aigQ",label:"Recognize preeclampsia with severe features, and recall its pathogenesis.",children:[]},{type:"question",id:"ebaxsQ",label:"Recognize HELLP syndrome, and recall its associated liver pathology.",children:[]},{type:"question",id:"ibaJtQ",label:"Recognize chronic hypertension in pregnancy.",children:[]},{type:"question",id:"qqaCzl",label:"Recognize HELLP syndrome.",children:[]},{type:"question",id:"HGaK0m",label:"Recognize HELLP syndrome, and choose the most appropriate management for a patient at ≥ 34 weeks' gestation.",children:[]},{type:"question",id:"fEakEm",label:"Choose the appropriate prophylactic medication for pregnant women at high risk of developing preeclampsia.",children:[]},{type:"question",id:"iCaJ75",label:"Recognize preeclampsia without severe features, and choose the most appropriate outpatient management.",children:[]},{type:"question",id:"wCah85",label:"Choose the most appropriate antihypertensive therapy in pregnancy.",children:[]}]},{type:"article",id:"2f0Tl2/UO0b7T",label:"Antepartum hemorrhage",children:[{type:"question",id:"kq0mAS",label:"Recognize placenta previa with active bleeding, and choose the most appropriate next step in management.",children:[]},{type:"question",id:"5q0i_S",label:"Recognize ruptured vasa previa.",children:[]},{type:"question",id:"yq0dah",label:"Recognize maternal cocaine use, and recall its complications in pregnancy.",children:[]},{type:"question",id:"sI0tVh",label:"Recognize placenta 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management in the setting of hemodynamic instability and fetal distress.",children:[]},{type:"question",id:"XA09Ri",label:"Recognize placenta previa, and recall its ultrasound findings.",children:[]},{type:"question",id:"_8a56m",label:"Recognize placenta previa, and choose the most appropriate timing for follow-up ultrasonography.",children:[]}]},{type:"article",id:"2f0Tl2/2O0T7T",label:"Gestational trophoblastic disease",children:[{type:"question",id:"DI01Uh",label:"Recognize gestational trophoblastic disease, and choose the most appropriate diagnostic test.",children:[]},{type:"question",id:"wI0hUh",label:"Recognize theca lutein cysts associated with high hCG levels.",children:[]},{type:"question",id:"gr0Fgh",label:"Recognize complete hydatidiform mole, and choose the most appropriate initial management.",children:[]},{type:"question",id:"hr0cSh",label:"Recognize an incomplete hydatidiform mole, and recall its ultrasonographic features.",children:[]},{type:"question",id:"n0a7gQ",label:"Recognize a complete hydatidiform mole, and recall its genetic origin.",children:[]},{type:"question",id:"5YaipQ",label:"Recognize theca lutein cysts associated with molar pregnancy.",children:[]},{type:"question",id:"GYaBqQ",label:"Recognize partial molar pregnancy.",children:[]}]},{type:"article",id:"2f0Tl2/fO0k7T",label:"Ectopic pregnancy",children:[{type:"question",id:"zj0r1T",label:"Recognize ruptured ectopic pregnancy presenting with hemorrhagic shock, and choose the initial step in resuscitation.",children:[]},{type:"question",id:"MO0MGT",label:"Recognize an interstitial pregnancy.",children:[]},{type:"question",id:"Cq0q0h",label:"Recognize the potential for ectopic pregnancy in a woman of reproductive age presenting with abdominal pain, and choose the initial diagnostic test.",children:[]},{type:"question",id:"7I04Vh",label:"Recognize interstitial pregnancy in an Rh-negative patient, and choose the most appropriate management including prevention of alloimmunization.",children:[]},{type:"question",id:"-uaDFm",label:"Recognize ectopic pregnancy with features of impending rupture, and choose the most appropriate intervention.",children:[]}]},{type:"article",id:"2f0Tl2/gO0F7T",label:"Pregnancy loss",children:[{type:"question",id:"jq0_yS",label:"Recognize a complete abortion.",children:[]},{type:"question",id:"Mq0M_S",label:"Recognize threatened abortion, and choose the most appropriate management.",children:[]},{type:"question",id:"zI0r2h",label:"Recognize inevitable abortion with hemodynamic instability, and choose the most appropriate management.",children:[]},{type:"question",id:"-I0D2h",label:"Recognize intrauterine fetal demise, and choose the most appropriate management step.",children:[]},{type:"question",id:"Sr0ygh",label:"Choose the most appropriate next step in management after a stillbirth.",children:[]},{type:"question",id:"ir0JSh",label:"Recognize disseminated intravascular coagulation, and recall its triggers.",children:[]},{type:"question",id:"5r0i3h",label:"Recognize incomplete abortion, and choose the most appropriate management in a stable patient.",children:[]},{type:"question",id:"-70Doh",label:"Recognize septic abortion, and choose the most appropriate initial management.",children:[]},{type:"question",id:"itaJWm",label:"Recognize a missed abortion.",children:[]}]},{type:"article",id:"2f0Tl2/3O0SHT",label:"Normal labor and delivery",children:[{type:"question",id:"gn0Fsg",label:"Recognize compression of the common peroneal nerve.",children:[]},{type:"question",id:"IK0Y3S",label:"Recognize alobar holoprosencephaly, and choose the most appropriate next step in management.",children:[]},{type:"question",id:"EI08eh",label:"Recognize recurrent variable decelerations indicating umbilical cord compression, and choose initial intrauterine resuscitation measures.",children:[]},{type:"question",id:"vI0Aeh",label:"Recognize umbilical cord compression.",children:[]},{type:"question",id:"jr0_Sh",label:"Recognize fetal head compression.",children:[]},{type:"question",id:"Pr0Whh",label:"Recognize fetal distress during labor, and choose the most appropriate intervention.",children:[]},{type:"question",id:"Jr0sRh",label:"Recognize active labor with unknown fetal presentation, and choose the most appropriate diagnostic test.",children:[]},{type:"question",id:"YUanbP",label:"Recognize third-degree perineal laceration, and recall its complications.",children:[]},{type:"question",id:"Ftag2m",label:"Recognize false labor, and choose the most appropriate management based on the absence of cervical changes and descent of the fetal presenting part.",children:[]},{type:"question",id:"cEaaum",label:"Choose the most appropriate fetal heart rate monitoring method when external monitoring fails due to maternal obesity.",children:[]},{type:"question",id:"avaQAm",label:"Recognize obstetric trauma as a cause of fecal incontinence.",children:[]},{type:"question",id:"DBa11M",label:"Recognize normal progression of labor with bloody show, and choose reassurance and continuous monitoring as management.",children:[]}]},{type:"article",id:"2f0Tl2/RO0lHT",label:"Uterine rupture",children:[{type:"question",id:"Eq08Zh",label:"Recognize uterine rupture.",children:[]},{type:"question",id:"uI0peh",label:"Recognize uterine rupture, and recall its most specific physical examination finding.",children:[]},{type:"question",id:"dEaoum",label:"Recognize uterine rupture during labor, and choose the most appropriate immediate intervention.",children:[]},{type:"question",id:"VEaGum",label:"Recognize history of cesarean delivery as a risk factor for uterine rupture.",children:[]}]},{type:"article",id:"2f0Tl2/iO0JHT",label:"Postpartum care",children:[{type:"question",id:"NQ0-wf",label:"Recognize normal postpartum course, and choose the most appropriate management.",children:[]}]},{type:"article",id:"2f0Tl2/al0QvT",label:"Fetal growth restriction",children:[{type:"question",id:"_r05Ph",label:"Recognize placental insufficiency.",children:[]},{type:"question",id:"l70vNh",label:"Recognize asymmetrical intrauterine growth restriction, and recall its risk factors.",children:[]},{type:"question",id:"duaoJm",label:"Recognize intrauterine growth restriction, and choose the most appropriate diagnostic test.",children:[]}]},{type:"article",id:"2f0Tl2/Yl0nvT",label:"Multiple pregnancy",children:[{type:"question",id:"qr0CRh",label:"Recognize dichorionic-diamniotic twins.",children:[]},{type:"question",id:"BC0z8R",label:"Recognize monochorionic-diamniotic monozygotic twins with twin-to-twin transfusion syndrome.",children:[]},{type:"question",id:"HbaKEQ",label:"Recognize monochorionic-diamniotic monozygotic twinning.",children:[]},{type:"question",id:"HtaKUm",label:"Recognize monochorionic-monoamniotic twin pregnancy, and choose the most appropriate next step in management.",children:[]},{type:"question",id:"Xwa9h5",label:"Recognize monochorionic monoamniotic twin pregnancy, and recall its complications.",children:[]}]},{type:"article",id:"2f0Tl2/Xl09vT",label:"Abnormal labor and delivery",children:[{type:"question",id:"xI0EUh",label:"Recognize premature rupture of membranes (PROM), and recall its most common risk factor.",children:[]},{type:"question",id:"yI0d2h",label:"Recognize arrested active phase of labor, and choose the most appropriate next step in management.",children:[]},{type:"question",id:"kr0mhh",label:"Recognize persistent variable decelerations, and choose the most appropriate intervention.",children:[]},{type:"question",id:"nr073h",label:"Recognize preterm prelabor rupture of membranes, and choose the most appropriate management.",children:[]},{type:"question",id:"rr0fih",label:"Recognize fetal transverse lie in active labor, and choose the most appropriate delivery method.",children:[]},{type:"question",id:"Cr0qjh",label:"Choose the most appropriate next step in management for a fetus in breech presentation at 38 weeks' gestation.",children:[]},{type:"question",id:"xr0Ejh",label:"Recognize the normal progression of the second stage of labor in a nulliparous woman, and choose the most appropriate next step in management.",children:[]},{type:"question",id:"Br0zjh",label:"Recognize breech presentation before 37 weeks' gestation, and choose the most appropriate management.",children:[]},{type:"question",id:"yr0dPh",label:"Recognize prolonged second stage of labor, and choose the most appropriate next step in management.",children:[]},{type:"question",id:"GKaB3l",label:"Recognize fetal macrosomia, and recall its complications.",children:[]},{type:"question",id:"statUm",label:"Recognize arrest of fetal descent during labor, and choose the appropriate intervention.",children:[]},{type:"question",id:"Cuaqtm",label:"Recognize breech presentation, and recall its complications during labor.",children:[]},{type:"question",id:"AuaRFm",label:"Recognize umbilical cord prolapse, and choose the most appropriate next step in management.",children:[]},{type:"question",id:"ZEaZ8m",label:"Recall complications of forceps-assisted delivery.",children:[]},{type:"question",id:"bEaH8m",label:"Recognize protracted active phase of labor, and choose the most appropriate next step in management.",children:[]},{type:"question",id:"1Ea2um",label:"Recognize preterm premature rupture of membranes (PPROM), and choose the initial diagnostic step.",children:[]}]},{type:"article",id:"2f0Tl2/el0xDT",label:"Neural tube defects",children:[{type:"question",id:"9z0NEi",label:"Recognize spina bifida cystica with elevated maternal serum α-fetoprotein.",children:[]},{type:"question",id:"LtawVm",label:"Recognize anencephaly as a neural tube defect, and choose the appropriate prenatal intervention to prevent this condition.",children:[]}]},{type:"article",id:"2f0Tl2/Sl0ywT",label:"Regional anesthesia",children:[{type:"question",id:"V70Gkh",label:"Recognize sympathetic block as a cause of hypotension post-epidural anesthesia.",children:[]}]},{type:"article",id:"2f0Tl2/RN0lag",label:"Prenatal care",children:[{type:"question",id:"gK0FfS",label:"Recognize Down syndrome, and recall its prenatal diagnostic findings.",children:[]},{type:"question",id:"hK0cTS",label:"Recognize the need for noninvasive prenatal screening for Down syndrome, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"3K0STS",label:"Recognize the high risk of Down syndrome, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"-q0Dah",label:"Choose the most appropriate preconceptional recommendation regarding nutrient supplementation.",children:[]},{type:"question",id:"WI0Pbh",label:"Choose the most appropriate screening test for gestational diabetes at 24 weeks' gestation.",children:[]},{type:"question",id:"UI0bXh",label:"Recognize early pregnancy, and recall the most accurate predictor of gestational age.",children:[]},{type:"question",id:"PI0W1h",label:"Choose the most appropriate physical activity recommendations for a pregnant patient.",children:[]},{type:"question",id:"AI0R2h",label:"Recognize the high risk of Down syndrome from prenatal screening results, and choose the most appropriate diagnostic test for confirmation.",children:[]},{type:"question",id:"0r0efh",label:"Recognize abnormal biophysical profile in pregnancy, and choose the most appropriate next step in management.",children:[]},{type:"question",id:"Yr0nfh",label:"Recognize the recommended prenatal infection screenings, and choose the appropriate tests for a first prenatal visit.",children:[]},{type:"question",id:"fr0kgh",label:"Recognize elevated maternal serum α-fetoprotein in neural tube defects.",children:[]},{type:"question",id:"4r03hh",label:"Recognize intrauterine growth restriction and oligohydramnios, and choose the most appropriate fetal surveillance method.",children:[]},{type:"question",id:"Dca1ej",label:"Recognize the screening results suggestive of Down syndrome, and recall the diagnostic finding to confirm the diagnosis.",children:[]},{type:"question",id:"KkaUKk",label:"Recognize group B streptococcus colonization in pregnancy, and choose the appropriate timing and intervention to decrease vertical transmission.",children:[]},{type:"question",id:"sMatJO",label:"Recognize underestimation of gestational age as a cause of abnormal alpha-fetoprotein levels.",children:[]},{type:"question",id:"3taSWm",label:"Recognize the importance of prenatal screening for Group B streptococcus, and choose the appropriate intervention to reduce the risk of neonatal sepsis.",children:[]},{type:"question",id:"syatgM",label:"Recognize individuals at risk of developing gestational diabetes, and choose the most appropriate management.",children:[]}]},{type:"article",id:"2f0Tl2/dm0oeg",label:"Pharmacotherapy during pregnancy",children:[{type:"question",id:"XL09wg",label:"Recognize fetal hydantoin syndrome, and recall its association with maternal phenytoin therapy.",children:[]},{type:"question",id:"Lr0w3h",label:"Recall the teratogenic effects of valproic acid.",children:[]},{type:"question",id:"8-0O_i",label:"Recognize the teratogenic effects of valproic acid, and recall the interventions for neural tube defects.",children:[]},{type:"question",id:"RSalzP",label:"Recognize the teratogenic effects of carbamazepine, and recall the complications associated with folate antagonism in pregnancy.",children:[]},{type:"question",id:"6xajx5",label:"Recognize fetal renal hypoplasia due to in utero exposure, and recall the teratogenic effects of ACE inhibitors.",children:[]}]},{type:"article",id:"2f0Tl2/2m0TUg",label:"Parenteral anticoagulation",children:[{type:"question",id:"KQaUC4",label:"Recognize deep vein thrombosis in pregnancy, and choose the most appropriate pharmacotherapy.",children:[]}]},{type:"article",id:"2f0Tl2/mm0VTg",label:"Overview of antibiotic therapy",children:[{type:"question",id:"hracSN",label:"Choose the most appropriate antibiotic for Ureaplasma infection during pregnancy.",children:[]}]},{type:"article",id:"2f0Tl2/Bm0z3g",label:"Influenza",children:[{type:"question",id:"kxam95",label:"Recognize influenza infection in a pregnant patient, and choose the most appropriate antiviral therapy.",children:[]}]},{type:"article",id:"2f0Tl2/zm0rRg",label:"Immunization schedule",children:[{type:"question",id:"GQ0Bxf",label:"Choose the appropriate vaccines for a pregnant woman in her third trimester.",children:[]}]},{type:"article",id:"2f0Tl2/gM0FLg",label:"Chorioamnionitis, neonatal infection, and omphalitis",children:[{type:"question",id:"VQ0GEf",label:"Recognize late-onset neonatal sepsis, and choose the initial empirical antibiotic therapy.",children:[]},{type:"question",id:"oQ00Cf",label:"Recognize chorioamnionitis in the context of pregnancy.",children:[]},{type:"question",id:"8Q0OBf",label:"Recognize early-onset neonatal sepsis, and recall the most common pathogen.",children:[]},{type:"question",id:"xQ0Eyf",label:"Recognize chorioamnionitis with preterm premature rupture of membranes (PPROM), and choose the most appropriate management in labor induction.",children:[]},{type:"question",id:"Ij0YbT",label:"Choose the most appropriate management for preventing neonatal GBS infection in labor.",children:[]},{type:"question",id:"hvac-m",label:"Choose the most appropriate intrapartum antibiotic prophylaxis for group B Streptococcus in a patient with a history of penicillin allergy.",children:[]}]},{type:"article",id:"2f0Tl2/mM0V6g",label:"Postpartum hemorrhage",children:[{type:"question",id:"mI0VWh",label:"Recognize uterine atony as a cause of postpartum hemorrhage.",children:[]},{type:"question",id:"br0Hfh",label:"Distinguish placenta accreta from other causes of antepartum or peripartum hemorrhage.",children:[]},{type:"question",id:"Ir0Yih",label:"Recognize uterine inversion.",children:[]},{type:"question",id:"yC0duR",label:"Recognize postpartum hemorrhage due to uterine atony, and choose the initial management step.",children:[]},{type:"question",id:"GUaBeP",label:"Recognize postpartum hemorrhage due to uterine atony, and recall the mechanism of action of oxytocin.",children:[]},{type:"question",id:"aOaQIk",label:"Recognize placenta accreta, and recall its association with prior Cesarean sections.",children:[]},{type:"question",id:"fHakpN",label:"Recognize injury to the cervix as a cause of postpartum hemorrhage.",children:[]},{type:"question",id:"88aOom",label:"Recognize postpartum hemorrhage due to uterine atony, and choose the initial management step.",children:[]},{type:"question",id:"jva_-m",label:"Recognize acute uterine inversion, and choose the most appropriate initial management step.",children:[]}]},{type:"article",id:"2f0Tl2/sM0tJg",label:"Atelectasis",children:[{type:"question",id:"ur0pQh",label:"Recognize postoperative atelectasis.",children:[]}]},{type:"article",id:"2f0Tl2/Sn0ysg",label:"Bacteria overview",children:[{type:"question",id:"hYacKQ",label:"Recognize neonatal sepsis, and recall the characteristics of Streptococcus agalactiae.",children:[]}]},{type:"article",id:"2f0Tl2/Pn0Wtg",label:"General virology",children:[{type:"question",id:"Xaa9QQ",label:"Recognize the use of palivizumab in immunocompromised infants, and recall the transmission route of RSV.",children:[]},{type:"question",id:"oPa0fk",label:"Recognize Parvovirus B19 infection, and recall its effects on the fetus.",children:[]}]},{type:"article",id:"2f0Tl2/sL0t_g",label:"Nonthrombotic embolism",children:[{type:"question",id:"pw0LPR",label:"Recognize amniotic fluid embolism.",children:[]}]},{type:"article",id:"2f0Tl2/Xo090S",label:"Zika virus infection",children:[{type:"question",id:"QrauSN",label:"Recognize Zika virus infection and its transmission, and choose the appropriate preventive measure during pregnancy.",children:[]}]},{type:"article",id:"2f0Tl2/Oo0IXS",label:"Cyanotic congenital heart defects",children:[{type:"question",id:"z40rNT",label:"Recognize transposition of the great arteries, and choose the most appropriate initial management.",children:[]},{type:"question",id:"qH0Crh",label:"Recognize the teratogenic effects of lithium, and recall its impact on fetal cardiac development.",children:[]},{type:"question",id:"AZaRVQ",label:"Recognize Ebstein anomaly, and recall its association with lithium use during pregnancy.",children:[]}]},{type:"article",id:"2f0Tl2/5o0icS",label:"Cerebral palsy",children:[{type:"question",id:"WBYP-r",label:"Recognize cerebral palsy, and recall the antenatal intervention to prevent this condition.",children:[]}]},{type:"article",id:"2f0Tl2/6o0j1S",label:"Purines and pyrimidines",children:[{type:"question",id:"WkaP5k",label:"Recognize the use of methotrexate in ectopic pregnancy, and recall its mechanism of action.",children:[]}]},{type:"article",id:"2f0Tl2/Fo0gdS",label:"Preterm labor and birth",children:[{type:"question",id:"Jq0szS",label:"Recognize history of spontaneous preterm birth as a strong risk factor for preterm delivery.",children:[]},{type:"question",id:"Qr0uSh",label:"Recognize preterm labor, and choose the most appropriate neuroprotective management.",children:[]},{type:"question",id:"2EaTEm",label:"Recognize the risk factors for preterm delivery, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"c-aawM",label:"Recall risk factors for preterm delivery.",children:[]}]},{type:"article",id:"2f0Tl2/vo0AdS",label:"Embryogenesis",children:[{type:"question",id:"16a2Pl",label:"Recognize amniotic band syndrome, and recall the type of embryological abnormality it represents.",children:[]}]},{type:"article",id:"2f0Tl2/Do01VS",label:"The placenta, umbilical cord, and amniotic sac",children:[{type:"question",id:"jE0_v3",label:"Recall the function of human chorionic gonadotropin (hCG) in early pregnancy.",children:[]},{type:"question",id:"FnagEO",label:"Recall the functions of human chorionic gonadotropin (hCG) during pregnancy.",children:[]}]},{type:"article",id:"2f0Tl2/wo0hVS",label:"Prenatal and postnatal physiology",children:[{type:"question",id:"yladzk",label:"Recall fetal blood circulation, and recall the function of the ductus venosus.",children:[]}]},{type:"article",id:"2f0Tl2/W60PPS",label:"Skin and skin appendage",children:[{type:"question",id:"zdarsj",label:"Recognize oculocutaneous albinism, and recall the enzyme defect involved.",children:[]}]},{type:"article",id:"2f0Tl2/i60JkS",label:"Thyroid gland and parathyroid glands",children:[{type:"question",id:"LVawEj",label:"Recognize pregnancy as a hyperestrogenic state, and recall its effect on thyroid function tests.",children:[]}]},{type:"article",id:"2f0Tl2/_q05ah",label:"Maternal complications during pregnancy",children:[{type:"question",id:"Qq0uyS",label:"Recognize physiological changes of late pregnancy, and choose reassurance and monitoring as the management.",children:[]},{type:"question",id:"Wr0PTh",label:"Recognize relaxation of the pelvic girdle ligaments.",children:[]},{type:"question",id:"tr0XQh",label:"Recognize cervical insufficiency.",children:[]},{type:"question",id:"DA01Ni",label:"Recognize supine hypotensive syndrome in pregnancy, and choose the position to alleviate symptoms.",children:[]},{type:"question",id:"oKa0hl",label:"Recognize acute fatty liver of pregnancy.",children:[]},{type:"question",id:"9GaNYm",label:"Recognize acute fatty liver of pregnancy, and choose the most appropriate management.",children:[]},{type:"question",id:"ttaX2m",label:"Recognize hyperemesis gravidarum, and recall its associated ultrasound finding.",children:[]},{type:"question",id:"VuaGJm",label:"Recognize hyperemesis gravidarum, and recall its fetal complications.",children:[]},{type:"question",id:"YEan8m",label:"Recognize cervical insufficiency and choose the most appropriate intervention.",children:[]},{type:"question",id:"eEaxum",label:"Recognize the risk of cervical insufficiency due to a short cervix, and choose the most appropriate management.",children:[]},{type:"question",id:"IxaYB5",label:"Recognize polymorphic eruption of pregnancy, and choose the most appropriate management.",children:[]}]},{type:"article",id:"2f0Tl2/lI0v1h",label:"Hypokalemia",children:[{type:"question",id:"Cx0qAR",label:"Recognize terbutaline-induced hypokalemia, and choose the most appropriate diagnostic study.",children:[]}]},{type:"article",id:"2f0Tl2/Q70ulh",label:"Peripartum cardiomyopathy",children:[{type:"question",id:"4Ea3Dm",label:"Recognize peripartum cardiomyopathy.",children:[]},{type:"question",id:"kEamDm",label:"Recognize persistent left ventricular dysfunction post-peripartum, and choose the most appropriate counseling regarding future pregnancy.",children:[]}]},{type:"article",id:"2f0Tl2/oH00rh",label:"Vaginal bleeding",children:[{type:"question",id:"BHazsN",label:"Recognize an anembryonic pregnancy.",children:[]}]},{type:"article",id:"2f0Tl2/Rs0luh",label:"Diabetes mellitus in pregnancy",children:[{type:"question",id:"1p02oS",label:"Recognize gestational diabetes, and recall its neonatal complications.",children:[]},{type:"question",id:"9haNT4",label:"Recognize caudal regression syndrome, and recall its strongest predisposing factor.",children:[]}]},{type:"article",id:"2f0Tl2/Fs0g9h",label:"Family planning",children:[{type:"question",id:"yKadQl",label:"Recognize the need for preconception care, and choose the appropriate screening test for immunity status.",children:[]}]},{type:"article",id:"2f0Tl2/bt0HX3",label:"Opioid use disorder",children:[{type:"question",id:"vCaAF5",label:"Choose the most appropriate pharmacotherapy for opioid use disorder during pregnancy.",children:[]}]},{type:"article",id:"2f0Tl2/Xt09X3",label:"Cesarean delivery",children:[{type:"question",id:"Qvau-m",label:"Recognize the importance of informing patients about prenatal childbirth education and obstetric analgesia options.",children:[]},{type:"question",id:"LBawYM",label:"Recognize indications for scheduled cesarean delivery in the context of previous classical cesarean incision.",children:[]}]},{type:"article",id:"2f0Tl2/2t0T13",label:"Late-term and postterm pregnancy",children:[{type:"question",id:"3vaS-m",label:"Recognize postterm pregnancy with oligohydramnios, and choose the most appropriate management.",children:[]}]},{type:"article",id:"2f0Tl2/nt07V3",label:"Neonatal conjunctivitis",children:[{type:"question",id:"1Q02Ef",label:"Choose the most appropriate management for neonatal chlamydial conjunctivitis.",children:[]},{type:"question",id:"4Q03wf",label:"Recognize neonatal gonococcal conjunctivitis, and choose the appropriate prophylactic medication to prevent it.",children:[]},{type:"question",id:"o_006i",label:"Recognize chlamydial conjunctivitis in a newborn, and recall its cause.",children:[]}]},{type:"article",id:"2f0Tl2/rt0fU3",label:"Contraception",children:[{type:"question",id:"hI0cch",label:"Recognize the need for contraception in postpartum breastfeeding women, and choose the appropriate contraceptive method.",children:[]}]},{type:"article",id:"2f0Tl2/N80-53",label:"Infant nutrition and breastfeeding",children:[{type:"question",id:"eJ0xGS",label:"Recall the complications associated with preterm birth related to nutrition.",children:[]},{type:"question",id:"JJ0sES",label:"Recognize contraindications to breastfeeding related to maternal substance use.",children:[]},{type:"question",id:"Nta-dm",label:"Recognize breast engorgement postpartum.",children:[]},{type:"question",id:"ZvaZAm",label:"Choose the most effective method to prevent nipple injury in primiparous women during breastfeeding.",children:[]}]},{type:"article",id:"2f0Tl2/r80fL3",label:"Polyhydramnios",children:[{type:"question",id:"5Eaiwm",label:"Recognize polyhydramnios and risk factors for gestational diabetes mellitus, and choose the appropriate screening test.",children:[]}]},{type:"article",id:"2f0Tl2/7804L3",label:"Oligohydramnios",children:[{type:"question",id:"Gr0Bih",label:"Recognize oligohydramnios, and recall its complications.",children:[]},{type:"question",id:"l0avTQ",label:"Recognize Potter sequence due to posterior urethral valves.",children:[]},{type:"question",id:"7aa4NQ",label:"Recognize Potter sequence and pulmonary hypoplasia due to oligohydramnios.",children:[]}]},{type:"article",id:"2f0Tl2/RE0lv3",label:"Postpartum complications",children:[{type:"question",id:"Yh0ncf",label:"Recognize postpartum endometritis, and choose the most appropriate antibiotic therapy.",children:[]},{type:"question",id:"4i037f",label:"Recognize postpartum endometritis.",children:[]},{type:"question",id:"ivaJ-m",label:"Recognize diastasis recti postpartum, and choose the most appropriate management for this condition.",children:[]},{type:"question",id:"yzadvM",label:"Recognize septic pelvic thrombophlebitis, and choose the most appropriate management.",children:[]}]}]},{type:"system",id:"L0/gf0Fl2",label:"Immune System",children:[{type:"article",id:"gf0Fl2/ef0xO2",label:"Tetanus",children:[{type:"question",id:"EUa8UP",label:"Recognize tetanus in an unvaccinated child, and choose the appropriate prophylactic measure to prevent the disease.",children:[]}]},{type:"article",id:"gf0Fl2/mf0V52",label:"Human immunodeficiency virus infection",children:[{type:"question",id:"cQ0aEf",label:"Recognize lactic acidosis with respiratory compensation, and recall the adverse effects of nucleoside reverse transcriptase inhibitors.",children:[]},{type:"question",id:"JF0sQ3",label:"Recognize congenital HIV infection, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"B90zpR",label:"Recall the adverse effects of HIV protease inhibitors.",children:[]},{type:"question",id:"hC0c7R",label:"Choose the preferred regimen for HIV postexposure prophylaxis following high-risk occupational exposure.",children:[]},{type:"question",id:"e0axUQ",label:"Recall the function of HIV gp120, and recall its role in the HIV infection process.",children:[]},{type:"question",id:"leav_j",label:"Recall the mechanism of action of HIV protease inhibitors, and recall their side effects.",children:[]},{type:"question",id:"IfaYnP",label:"Recall the changes in laboratory findings associated with a response to antiretroviral therapy.",children:[]},{type:"question",id:"-iaD84",label:"Recall the mechanism of action of zidovudine, and recall the process it inhibits in HIV replication.",children:[]},{type:"question",id:"HQaKx4",label:"Recall the role of CCR5 in HIV entry into host cells.",children:[]},{type:"question",id:"04ae3k",label:"Recall the adverse effects of antiretroviral protease inhibitors.",children:[]},{type:"question",id:"g4aFik",label:"Recall the mechanism of action of non-nucleoside reverse transcriptase inhibitors.",children:[]},{type:"question",id:"dkao5k",label:"Recall the function of the HIV pol gene and its role in antiretroviral drug resistance.",children:[]},{type:"question",id:"Qkaunk",label:"Recall the function of HIV envelope proteins, and recall the gene that encodes these proteins.",children:[]},{type:"question",id:"o7a05N",label:"Recognize acute retroviral syndrome, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"Tsa68N",label:"Recognize immune reconstitution inflammatory syndrome.",children:[]}]},{type:"article",id:"gf0Fl2/Lf0w52",label:"Infectious mononucleosis",children:[{type:"question",id:"6aajlQ",label:"Recognize infectious mononucleosis, and recall its potential complications.",children:[]}]},{type:"article",id:"gf0Fl2/If0Yn2",label:"Pneumocystis pneumonia",children:[{type:"question",id:"O60IOS",label:"Recognize Pneumocystis jirovecii pneumonia in an immunocompromised infant, and choose the most appropriate diagnostic study.",children:[]}]},{type:"article",id:"gf0Fl2/rf0fn2",label:"Candidiasis",children:[{type:"question",id:"gQaFv4",label:"Recognize oral thrush, and recall its association with T-cell deficiencies.",children:[]}]},{type:"article",id:"gf0Fl2/0T0e62",label:"Reactive arthritis",children:[{type:"question",id:"LB0wYi",label:"Recognize reactive arthritis, and recall its associated enthesitis.",children:[]}]},{type:"article",id:"gf0Fl2/1T02p2",label:"Giant cell arteritis",children:[{type:"question",id:"aj0Q_f",label:"Recognize giant cell arteritis, and recall the role of interleukin-6 in its pathophysiology.",children:[]}]},{type:"article",id:"gf0Fl2/dT0op2",label:"Systemic lupus erythematosus",children:[{type:"question",id:"pB0Lbi",label:"Recognize systemic lupus erythematosus, and recall its specific antibody markers.",children:[]}]},{type:"article",id:"gf0Fl2/fT0kJ2",label:"Vasculitides",children:[{type:"question",id:"AF0Rk3",label:"Recognize eosinophilic granulomatosis with polyangiitis (EGPA).",children:[]},{type:"question",id:"45a34O",label:"Recognize eosinophilic granulomatosis with polyangiitis.",children:[]}]},{type:"article",id:"gf0Fl2/TT06J2",label:"Granulomatosis with polyangiitis",children:[{type:"question",id:"wF0h43",label:"Recognize granulomatosis with polyangiitis, and recall its tissue biopsy findings.",children:[]}]},{type:"article",id:"gf0Fl2/PT0WI2",label:"Chronic myeloid leukemia",children:[{type:"question",id:"yF0dk3",label:"Recognize a leukemoid reaction.",children:[]}]},{type:"article",id:"gf0Fl2/oT0072",label:"Mycosis fungoides",children:[{type:"question",id:"ZmaZVO",label:"Recognize mycosis fungoides, and recall the associated neoplastic cell type.",children:[]}]},{type:"article",id:"gf0Fl2/ng07D2",label:"Nephritic syndrome",children:[{type:"question",id:"2G0TAh",label:"Recognize Goodpasture syndrome.",children:[]}]},{type:"article",id:"gf0Fl2/Lg0wD2",label:"Poststreptococcal glomerulonephritis",children:[{type:"question",id:"yXad0j",label:"Recognize poststreptococcal glomerulonephritis, and recall the role of immune complexes in its pathophysiology.",children:[]}]},{type:"article",id:"gf0Fl2/VS0GA2",label:"Crohn disease",children:[{type:"question",id:"ISaYa4",label:"Recognize Crohn disease, and recall the role of type 1 T helper cells in its pathogenesis.",children:[]}]},{type:"article",id:"gf0Fl2/9S0Nbf",label:"Acute rheumatic fever",children:[{type:"question",id:"bdaHoj",label:"Recognize group A streptococcal pharyngitis, and recall its potential complications.",children:[]},{type:"question",id:"WSaPAP",label:"Recognize rheumatic fever, and recall the role of M protein in its pathogenesis.",children:[]}]},{type:"article",id:"gf0Fl2/5h0ief",label:"Tuberculosis",children:[{type:"question",id:"1ia2q4",label:"Recognize the use of interferon-gamma release assays, and recall the pathogen they diagnose.",children:[]},{type:"question",id:"jNa_aO",label:"Recognize pulmonary tuberculosis, and recall the composition of caseating granulomas.",children:[]},{type:"question",id:"PNaWYO",label:"Recognize primary tuberculosis infection, and recall the initial immunologic process in its pathogenesis.",children:[]},{type:"question",id:"fnaksO",label:"Recognize pulmonary tuberculosis, and recall its immunological basis.",children:[]}]},{type:"article",id:"gf0Fl2/ZR0Zlf",label:"Meningitis",children:[{type:"question",id:"uSapY4",label:"Recognize meningococcal meningitis, and choose the most effective vaccination to prevent this infection.",children:[]}]},{type:"article",id:"gf0Fl2/hR0c5f",label:"Antiphospholipid syndrome",children:[{type:"question",id:"GcaBdj",label:"Recognize systemic lupus erythematosus with antiphospholipid syndrome, and recall the diagnostic finding of false-positive syphilis testing.",children:[]}]},{type:"article",id:"gf0Fl2/7R04of",label:"Guillain-Barr\xe9 syndrome",children:[{type:"question",id:"mB0VYi",label:"Recognize Guillain-Barr\xe9 syndrome, and recall the target of the autoimmune response.",children:[]},{type:"question",id:"jea_Aj",label:"Recognize Guillain-Barr\xe9 syndrome, and recall its CSF findings.",children:[]}]},{type:"article",id:"gf0Fl2/WQ0PEf",label:"Infection prevention and control",children:[{type:"question",id:"oDa025",label:"Recognize the guidelines for post-exposure prophylaxis follow-up, and recall when no further workup is indicated.",children:[]}]},{type:"article",id:"gf0Fl2/7Q04xf",label:"Benign bone tumors",children:[{type:"question",id:"Q6aukl",label:"Recognize Langerhans cell histiocytosis, and recall the characteristic cell type involved.",children:[]}]},{type:"article",id:"gf0Fl2/VP0GdT",label:"Cellular changes and adaptive responses",children:[{type:"question",id:"6MajpO",label:"Recognize autoimmune lymphoproliferative syndrome (ALPS), and recall its complications.",children:[]}]},{type:"article",id:"gf0Fl2/v40AOT",label:"Asplenia",children:[{type:"question",id:"Op0IpS",label:"Choose the most appropriate post-splenectomy prophylactic measure to prevent infections in pediatric patients.",children:[]},{type:"question",id:"5u0i73",label:"Choose the most appropriate infection prophylaxis strategy after emergency splenectomy.",children:[]},{type:"question",id:"iiaJr4",label:"Recognize sickle cell disease, and recall its impact on bacterial clearance.",children:[]}]},{type:"article",id:"gf0Fl2/Vk0G5T",label:"Seborrheic dermatitis",children:[{type:"question",id:"xv0EXR",label:"Recognize seborrheic dermatitis in an HIV-positive patient.",children:[]}]},{type:"article",id:"gf0Fl2/ek0x5T",label:"Hypersensitivity reactions",children:[{type:"question",id:"2O0T7T",label:"Recognize a type 1 hypersensitivity reaction, and choose the most appropriate next step in management.",children:[]},{type:"question",id:"Tx06DR",label:"Recognize a type 1 hypersensitivity reaction to latex, and choose the most appropriate pharmacotherapy.",children:[]},{type:"question",id:"7x04BR",label:"Choose the most appropriate management step for patients after a type I hypersensitivity reaction.",children:[]},{type:"question",id:"ny07fi",label:"Recognize anaphylaxis, and recall the mediators released from mast cells.",children:[]},{type:"question",id:"UaabPQ",label:"Recognize an Arthus reaction, and recall its pathophysiology.",children:[]},{type:"question",id:"wcahej",label:"Recognize acute graft rejection, and recall its underlying mechanism.",children:[]},{type:"question",id:"bUaHbP",label:"Recognize a type I hypersensitivity reaction, and recall its mediators.",children:[]},{type:"question",id:"SUaycP",label:"Recognize Goodpasture syndrome, and recall its hypersensitivity reaction type.",children:[]},{type:"question",id:"QUau1P",label:"Recognize myasthenia gravis, and recall its pathogenesis.",children:[]},{type:"question",id:"1la2Dk",label:"Recognize a type IV hypersensitivity reaction, and recall the role of interferon-γ.",children:[]}]},{type:"article",id:"gf0Fl2/2k0TMT",label:"Angioedema",children:[{type:"question",id:"lS0v-2",label:"Recognize hereditary angioedema, and recall its treatment targets.",children:[]}]},{type:"article",id:"gf0Fl2/4k03LT",label:"Psoriasis",children:[{type:"question",id:"jt0_W3",label:"Recognize psoriatic arthritis.",children:[]},{type:"question",id:"zB0rWi",label:"Recognize psoriasis, and recall its associated conditions.",children:[]}]},{type:"article",id:"gf0Fl2/7k046T",label:"Vitiligo",children:[{type:"question",id:"zG0rb3",label:"Recognize vitiligo, and recall its associated autoimmune conditions.",children:[]}]},{type:"article",id:"gf0Fl2/Fk0gpT",label:"Erythema nodosum",children:[{type:"question",id:"1F02S3",label:"Recognize erythema nodosum, and choose the most appropriate diagnostic test to evaluate for underlying systemic disease.",children:[]}]},{type:"article",id:"gf0Fl2/MO0MGT",label:"Overview of conjunctivitis",children:[{type:"question",id:"ew0x3R",label:"Recognize allergic conjunctivitis.",children:[]}]},{type:"article",id:"gf0Fl2/Pm0Wfg",label:"Antihistamines",children:[{type:"question",id:"_80563",label:"Recognize contraindications of first-generation antihistamines, and choose an appropriate alternative for allergic reactions.",children:[]},{type:"question",id:"_Ra5p4",label:"Choose the most appropriate pharmacotherapy for allergic rhinitis considering comorbid conditions.",children:[]}]},{type:"article",id:"gf0Fl2/4m03fg",label:"Chemotherapeutic agents",children:[{type:"question",id:"CkaqJk",label:"Recall drug interactions that increase toxicity of purine analogs.",children:[]},{type:"question",id:"8vaOb5",label:"Recognize methotrexate therapy for psoriatic arthritis, and recall its potential complications.",children:[]}]},{type:"article",id:"gf0Fl2/km0mfg",label:"Glucocorticoids",children:[{type:"question",id:"-A0Dmi",label:"Recognize giant cell arteritis, and recall the hematological effects of glucocorticoids.",children:[]}]},{type:"article",id:"gf0Fl2/mm0VTg",label:"Overview of antibiotic therapy",children:[{type:"question",id:"8XaO-Q",label:"Recognize acute epiglottitis due to Haemophilus influenzae, and recall the mechanism of action of rifampin.",children:[]}]},{type:"article",id:"gf0Fl2/Bm0z3g",label:"Influenza",children:[{type:"question",id:"Q_0uLi",label:"Recall the concept of antigenic drift in influenza viruses.",children:[]}]},{type:"article",id:"gf0Fl2/_m05Rg",label:"Vaccination",children:[{type:"question",id:"Ih0Y2f",label:"Recognize contraindications for routine vaccinations in infants, and choose the appropriate vaccine to withhold based on patient history.",children:[]},{type:"question",id:"lr0vhh",label:"Recognize vaccine-associated rash, and recall the concept of live attenuated vaccine replication.",children:[]},{type:"question",id:"G_0Bpi",label:"Recall the pathogens targeted by conjugate vaccines.",children:[]}]},{type:"article",id:"gf0Fl2/zm0rRg",label:"Immunization schedule",children:[{type:"question",id:"qF0CQ3",label:"Choose the most appropriate vaccination for an HIV-positive patient with a CD4+ count above 200 cells/mm3.",children:[]},{type:"question",id:"TC06rR",label:"Choose the appropriate immunization for an HIV-positive patient with a low CD4 count.",children:[]},{type:"question",id:"CNaqWO",label:"Recognize contraindications for live attenuated vaccines in HIV patients with low CD4 counts.",children:[]}]},{type:"article",id:"gf0Fl2/550ikg",label:"Postoperative management",children:[{type:"question",id:"UFabhm",label:"Recognize surgically induced tissue trauma as a cause of immediate postoperative fever.",children:[]}]},{type:"article",id:"gf0Fl2/x50Emg",label:"Adaptive immune system",children:[{type:"question",id:"1-02wi",label:"Recall the properties of immunoglobulin M (IgM) upon secretion.",children:[]},{type:"question",id:"W-0Pwi",label:"Recall the role of CD40 and CD40 ligand in immunoglobulin class switching, and recall the process of B cell activation.",children:[]},{type:"question",id:"Ucabbj",label:"Recall the concept of passive immunity in newborns.",children:[]},{type:"question",id:"veaA0P",label:"Recall the properties of live attenuated vaccines that induce strong immune responses.",children:[]},{type:"question",id:"efaxOP",label:"Recall the function of IgA, and recall the cytokine that induces B-cell class switching to IgA.",children:[]},{type:"question",id:"sTatHP",label:"Recognize the role of the third branchial pouch in embryological development, and recall the clinical presentation of thymic aplasia.",children:[]},{type:"question",id:"1Ra2N4",label:"Recognize thymoma-associated paraneoplastic syndromes, and recall the process of negative T-cell selection in the thymus.",children:[]},{type:"question",id:"WRaPN4",label:"Recall the function of the Fc region of IgG.",children:[]},{type:"question",id:"Z4aZ3k",label:"Recall the function of germinal centers, and recall the process of isotype switching.",children:[]},{type:"question",id:"JOastk",label:"Recognize T-cell anergy in HIV, and recall the role of B7-CD28 interaction in T-cell activation.",children:[]},{type:"question",id:"9paN7l",label:"Recall the target of the checkpoint inhibitor ipilimumab.",children:[]}]},{type:"article",id:"gf0Fl2/QM0uog",label:"Food allergies",children:[{type:"question",id:"rEafCm",label:"Recognize anaphylactic reactions to specific food allergens, and choose the most appropriate dietary recommendation for management.",children:[]}]},{type:"article",id:"gf0Fl2/qM0Cpg",label:"Immunosuppressants",children:[{type:"question",id:"6g0jw2",label:"Recall the adverse effects of calcineurin inhibitors used in transplant rejection prophylaxis.",children:[]},{type:"question",id:"fF0kh3",label:"Choose the most appropriate monitoring for patients on calcineurin inhibitors.",children:[]},{type:"question",id:"TF06h3",label:"Recognize the side effects of cyclosporine, and recall its uses.",children:[]},{type:"question",id:"kF0mR3",label:"Recall the adverse effects of immunosuppressant drugs used in transplant rejection prophylaxis.",children:[]},{type:"question",id:"3UaS1P",label:"Recognize methotrexate toxicity, and recall its mechanism of action.",children:[]},{type:"question",id:"lhavV4",label:"Recognize reduced clinical responsiveness to biologic agents, and recall the role of antidrug antibodies.",children:[]}]},{type:"article",id:"gf0Fl2/tM0Xqg",label:"Congenital immunodeficiency disorders",children:[{type:"question",id:"wK0hiS",label:"Recognize disseminated tuberculosis in the context of a congenital T-cell immunodeficiency, and recall the diagnostic finding.",children:[]},{type:"question",id:"9K0NiS",label:"Recognize chronic granulomatous disease.",children:[]},{type:"question",id:"yK0dQS",label:"Recognize X-linked agammaglobulinemia, and recall its genetic basis.",children:[]},{type:"question",id:"zK0rQS",label:"Recognize Wiskott-Aldrich syndrome.",children:[]},{type:"question",id:"W60PPS",label:"Recognize severe combined immunodeficiency (SCID).",children:[]},{type:"question",id:"E6085S",label:"Recognize hyper-IgM syndrome, and recall its genetic basis.",children:[]},{type:"question",id:"v60A5S",label:"Recognize DiGeorge syndrome, and recall the associated immune cell deficiency.",children:[]},{type:"question",id:"y60dnS",label:"Recognize leukocyte adhesion deficiency type 1, and recall its genetic defect.",children:[]},{type:"question",id:"ap0QLS",label:"Recognize Bruton agammaglobulinemia, and recall the role of maternal IgG in infancy.",children:[]},{type:"question",id:"FH0gHh",label:"Recognize autosomal dominant hyperimmunoglobulin E syndrome, and recall its effect on neutrophil function.",children:[]},{type:"question",id:"hy0cUi",label:"Recall the pathogens associated with terminal complement deficiencies.",children:[]},{type:"question",id:"my0Vfi",label:"Recognize severe combined immunodeficiency (SCID), and recall its genetic basis.",children:[]},{type:"question",id:"WA0Pii",label:"Recognize C3 deficiency, and recall its role in opsonization.",children:[]},{type:"question",id:"wz0hEi",label:"Recognize Chediak-Higashi syndrome, and recall the genetic defect involved.",children:[]},{type:"question",id:"QYauKQ",label:"Recognize chronic granulomatous disease, and recall the function of NADPH oxidase.",children:[]},{type:"question",id:"Scaybj",label:"Recognize severe combined immunodeficiency (SCID), and recall its effect on lymphocyte counts.",children:[]},{type:"question",id:"2WaTkj",label:"Recall the enzyme deficiency associated with recurrent Candida infections and a normal nitroblue tetrazolium test.",children:[]},{type:"question",id:"Feag0P",label:"Recognize severe congenital neutropenia.",children:[]},{type:"question",id:"WfaPOP",label:"Recognize X-linked agammaglobulinemia, and recall its genetic cause.",children:[]},{type:"question",id:"2faTlP",label:"Recognize chronic mucocutaneous candidiasis, and recall the role of T cells in its pathogenesis.",children:[]},{type:"question",id:"lgavvP",label:"Recognize Giardia lamblia infection, and recall complications of selective IgA deficiency.",children:[]},{type:"question",id:"MhaMe4",label:"Recognize miliary tuberculosis, and recall the associated immunodeficiency.",children:[]},{type:"question",id:"MkaMok",label:"Recognize chronic granulomatous disease, and recall the organisms it predisposes to infection.",children:[]},{type:"question",id:"hOacHk",label:"Recognize IPEX syndrome, and recall its complications.",children:[]},{type:"question",id:"SNay0O",label:"Recognize leukocyte adhesion deficiency type 1, and recall its genetic basis.",children:[]},{type:"question",id:"dmaoeO",label:"Recognize hyper-IgM syndrome, and recall its associated defect in immune function.",children:[]},{type:"question",id:"ymadRO",label:"Recognize chronic granulomatous disease, and recall the function of the NADPH oxidase complex.",children:[]},{type:"question",id:"AHaRGN",label:"Recognize Job syndrome, and recall its effect on immunoglobulin isotype concentrations.",children:[]},{type:"question",id:"usap9N",label:"Recognize common variable immunodeficiency (CVID), and recall its associated autoimmune complications.",children:[]},{type:"question",id:"2GaTAN",label:"Recognize X-linked agammaglobulinemia.",children:[]},{type:"question",id:"TGa6AN",label:"Recognize selective IgA deficiency, and recall the associated infections.",children:[]},{type:"question",id:"kwamQ5",label:"Recognize recurrent meningococcal infections, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"FzaguM",label:"Recognize X-linked agammaglobulinemia, and choose the appropriate prophylactic treatment to prevent recurrent infections.",children:[]}]},{type:"article",id:"gf0Fl2/gn0Fsg",label:"Transplantation",children:[{type:"question",id:"Q50uPg",label:"Recognize acute cellular rejection of a renal allograft.",children:[]},{type:"question",id:"s50tlg",label:"Recognize acute renal allograft rejection, and choose the initial treatment step.",children:[]},{type:"question",id:"TK06fS",label:"Recognize acute liver transplant rejection, and choose the most appropriate diagnostic study.",children:[]},{type:"question",id:"iw0JiR",label:"Choose the appropriate prophylactic medication for post-kidney transplantation patients.",children:[]},{type:"question",id:"EA08li",label:"Recognize graft-versus-host disease, and recall its pathophysiology.",children:[]},{type:"question",id:"FYagIQ",label:"Recognize acute renal allograft rejection, and recall its underlying mechanism.",children:[]},{type:"question",id:"zcarUj",label:"Recognize hyperacute graft rejection, and recall its immunological cause.",children:[]},{type:"question",id:"VGaGyN",label:"Recognize acute graft-versus-host disease.",children:[]}]},{type:"article",id:"gf0Fl2/Sn0ysg",label:"Bacteria overview",children:[{type:"question",id:"7y04gi",label:"Recognize gonococcal urethritis, and recall the mechanism of antigenic variation in Neisseria gonorrhoeae.",children:[]}]},{type:"article",id:"gf0Fl2/Pn0Wtg",label:"General virology",children:[{type:"question",id:"6Pajfk",label:"Recall the role of CD21 in Epstein-Barr virus infection.",children:[]}]},{type:"article",id:"gf0Fl2/ln0vtg",label:"Basics of hematology",children:[{type:"question",id:"MmaMTO",label:"Recall the characteristics and functions of natural killer cells.",children:[]}]},{type:"article",id:"gf0Fl2/Ln0wFg",label:"Laboratory medicine",children:[{type:"question",id:"RYalKQ",label:"Recognize a leukemoid reaction.",children:[]},{type:"question",id:"HqaK-l",label:"Recognize acute bacterial infection as a cause of neutrophilia.",children:[]}]},{type:"article",id:"gf0Fl2/mL0Vyg",label:"Herpes simplex virus infections",children:[{type:"question",id:"q1aC3j",label:"Recognize recurrent genital herpes, and recall its latency in sensory neurons.",children:[]}]},{type:"article",id:"gf0Fl2/rL0f_g",label:"Hemolytic uremic syndrome",children:[{type:"question",id:"p-0Lyi",label:"Recognize hemolytic uremic syndrome caused by Escherichia coli infection.",children:[]}]},{type:"article",id:"gf0Fl2/vL0Azg",label:"Hypothermia and 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patients.",children:[]},{type:"question",id:"iOaJHk",label:"Choose the appropriate prophylactic treatment for an HIV-infected patient with a CD4+ count <200/mm3.",children:[]},{type:"question",id:"9laN_k",label:"Recognize Pneumocystis jirovecii pneumonia, and recall the opportunistic infections prevented by trimethoprim-sulfamethoxazole therapy.",children:[]},{type:"question",id:"nFa7im",label:"Recall the prophylactic uses of trimethoprim-sulfamethoxazole in HIV patients.",children:[]}]},{type:"article",id:"gf0Fl2/Ho0KWS",label:"Bone tissue",children:[{type:"question",id:"cgaa8P",label:"Recall the role of cytokines in bone remodeling and healing.",children:[]}]},{type:"article",id:"gf0Fl2/1K022S",label:"Innate immune system",children:[{type:"question",id:"W1aPfj",label:"Recognize trichinellosis, and recall its immune defense mechanism.",children:[]},{type:"question",id:"jga_EP",label:"Recall the function of NOD-like receptors, and recall the role of NF-κB in the innate immune response.",children:[]},{type:"question",id:"9OaNuk",label:"Recall the role of myeloperoxidase in the coloration of pus.",children:[]},{type:"question",id:"ONaIYO",label:"Recall the structure of MHC I molecules, and recall their role in antigen presentation to CD8+ T-lymphocytes.",children:[]},{type:"question",id:"1Ia2bN",label:"Recall the mechanism of action of proteasome inhibitors, and recall their effect on CD8+ T cell activation.",children:[]}]},{type:"article",id:"gf0Fl2/W60PPS",label:"Skin and skin appendage",children:[{type:"question",id:"Ujab-4",label:"Recognize HIV meningoencephalitis, and recall the cell types targeted by HIV.",children:[]}]},{type:"article",id:"gf0Fl2/960NMS",label:"Lymphatic system",children:[{type:"question",id:"ox00xR",label:"Recognize uncomplicated bronchiolitis, and choose the most appropriate management.",children:[]},{type:"question",id:"ydadsj",label:"Recognize active pulmonary tuberculosis, and recall the location of macrophages in the lymph node.",children:[]}]},{type:"article",id:"gf0Fl2/hp0c6S",label:"Aging changes",children:[{type:"question",id:"8maOhO",label:"Recall the effect of aging on immune response to vaccines.",children:[]}]},{type:"article",id:"gf0Fl2/4p03pS",label:"Cytokines and eicosanoids",children:[{type:"question",id:"-B0DWi",label:"Recall the role of interleukin-1 in acute inflammation.",children:[]},{type:"question",id:"D0a1RQ",label:"Recall the mechanism of action of interleukin-2 analogs.",children:[]},{type:"question",id:"4Ya36Q",label:"Recognize acute hepatitis A virus infection, and recall the role of interferon in antiviral defense.",children:[]},{type:"question",id:"VWaG4j",label:"Recall the role of IL-8 in inflammation, and recall its function in neutrophil recruitment.",children:[]},{type:"question",id:"cTaapP",label:"Recognize neonatal sepsis, and recall effects of interleukin-6 on acute-phase proteins.",children:[]},{type:"question",id:"USab_P",label:"Recognize allergic bronchopulmonary 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pathophysiology.",children:[]}]},{type:"article",id:"gf0Fl2/rq0f-S",label:"Anaphylaxis",children:[{type:"question",id:"gk0FMT",label:"Recognize anaphylactic shock, and choose the most appropriate initial management.",children:[]},{type:"question",id:"aO0QIT",label:"Recognize anaphylaxis, and choose the most appropriate initial treatment.",children:[]},{type:"question",id:"FD0gTR",label:"Recognize a type I hypersensitivity reaction.",children:[]},{type:"question",id:"wKahil",label:"Recognize anaphylaxis, and choose the initial step to prevent recurrent episodes.",children:[]}]},{type:"article",id:"gf0Fl2/xH0Esh",label:"Mycobacterium avium complex infection",children:[{type:"question",id:"zu0rF3",label:"Recognize disseminated Mycobacterium avium complex infection in an AIDS patient, and choose the appropriate antimycobacterial pharmacotherapy.",children:[]},{type:"question",id:"BfazoP",label:"Recognize disseminated Mycobacterium avium complex infection in an AIDS patient, and choose the most appropriate pharmacotherapy.",children:[]}]},{type:"article",id:"gf0Fl2/BH0zsh",label:"Kaposi sarcoma",children:[{type:"question",id:"Q4auQk",label:"Recognize Kaposi sarcoma, and recall its causal organism.",children:[]}]},{type:"article",id:"gf0Fl2/yH0dGh",label:"Bacillary angiomatosis",children:[{type:"question",id:"5F0ii3",label:"Recognize bacillary angiomatosis in an HIV patient, and choose the most appropriate pharmacotherapy.",children:[]}]},{type:"article",id:"gf0Fl2/-H0DGh",label:"Autoimmune hemolytic anemia",children:[{type:"question",id:"wRah64",label:"Recognize cold agglutinin syndrome, and recall its associated laboratory findings.",children:[]}]},{type:"article",id:"gf0Fl2/Xs09th",label:"Allergic contact dermatitis",children:[{type:"question",id:"qy0CTi",label:"Recognize allergic contact dermatitis, and recall the cell type involved in type IV hypersensitivity reactions.",children:[]},{type:"question",id:"2-aT9M",label:"Choose the most appropriate management of 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treatment step.",children:[]}]},{type:"article",id:"gf0Fl2/480353",label:"Overview of viral hepatitides",children:[{type:"question",id:"nka7ok",label:"Recall the prevention of hepatitis D virus infection through hepatitis B vaccination.",children:[]}]},{type:"article",id:"gf0Fl2/A80R63",label:"Strongyloidiasis",children:[{type:"question",id:"7ba4EQ",label:"Recognize Strongyloides stercoralis infection, and recall its dermatologic manifestations.",children:[]}]}]},{type:"system",id:"L0/Tf06l2",label:"Skin & Subcutaneous Tissue",children:[{type:"article",id:"Tf06l2/ef0xO2",label:"Tetanus",children:[{type:"question",id:"pFaLQm",label:"Recognize the need for tetanus prophylaxis in a patient with a contaminated wound and uncertain immunization status, and choose the most appropriate immunization strategy.",children:[]}]},{type:"article",id:"Tf06l2/Uf0bl2",label:"Gas gangrene",children:[{type:"question",id:"ecaxYj",label:"Recognize gas gangrene, and recall the mechanism of cellular damage by 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expected serum finding.",children:[]}]},{type:"article",id:"Tf06l2/MS0MZf",label:"Primary biliary cholangitis",children:[{type:"question",id:"eA0xii",label:"Recognize xanthelasma, and recall its association with hypercholesterolemia.",children:[]}]},{type:"article",id:"Tf06l2/ch0a1f",label:"Peripheral arterial disease",children:[{type:"question",id:"zvarc5",label:"Recognize wet gangrene in the context of peripheral artery disease, and choose the most appropriate surgical management.",children:[]}]},{type:"article",id:"Tf06l2/1h021f",label:"Acute limb ischemia",children:[{type:"question",id:"Qp0u6S",label:"Recognize hair tourniquet syndrome.",children:[]}]},{type:"article",id:"Tf06l2/Uh0bWf",label:"Raynaud phenomenon",children:[{type:"question",id:"4_03oi",label:"Recognize primary Raynaud phenomenon, and choose the most appropriate pharmacotherapy.",children:[]}]},{type:"article",id:"Tf06l2/gh0FWf",label:"Chronic venous disease",children:[{type:"question",id:"q5aCOO",label:"Recognize chronic venous insufficiency, and recall its complications.",children:[]}]},{type:"article",id:"Tf06l2/Kh0UUf",label:"Wound healing",children:[{type:"question",id:"x_0Eqi",label:"Recognize the proliferative phase of wound healing, and recall its microscopic findings.",children:[]}]},{type:"article",id:"Tf06l2/ph0LUf",label:"Wound treatment",children:[{type:"question",id:"3qaSyl",label:"Recognize a noninfected, nonnecrotic stump ulcer, and choose the most appropriate management regarding prosthetic fit.",children:[]},{type:"question",id:"F9ag65",label:"Recognize factors affecting wound healing, and recall the impact of necrotic tissue on flap success.",children:[]}]},{type:"article",id:"Tf06l2/Jh0sUf",label:"Burns",children:[{type:"question",id:"lP0vUT",label:"Recognize full-thickness circumferential burns, and choose the most appropriate monitoring for complications.",children:[]},{type:"question",id:"JP0sfT",label:"Recognize impaired perfusion secondary to circumferential burn, and choose the most appropriate intervention.",children:[]},{type:"question",id:"mO0VGT",label:"Recognize superficial (1st-degree) sunburn, and choose the most appropriate symptomatic treatment.",children:[]},{type:"question",id:"_n05Dg",label:"Choose the initial treatment for chemical burns.",children:[]},{type:"question",id:"oOa0tk",label:"Calculate the burn surface area using the rule of nines.",children:[]},{type:"question",id:"DIa1UN",label:"Recall the metabolic changes following severe burns, and recall the phases of postburn hypermetabolic response.",children:[]},{type:"question",id:"iraJSN",label:"Recognize the burn depth.",children:[]},{type:"question",id:"lxav95",label:"Recognize third-degree burns affecting a significant percentage of total body surface area, and choose the most appropriate initial step in management.",children:[]}]},{type:"article",id:"Tf06l2/qh0CUf",label:"Skin and soft tissue infections",children:[{type:"question",id:"G30BPf",label:"Recognize Streptococcus 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severe inflammation, and choose the most appropriate next step in management.",children:[]},{type:"question",id:"Xxa9E5",label:"Recognize acute paronychia with abscess, and choose the most appropriate next step in management.",children:[]}]},{type:"article",id:"Tf06l2/7h042f",label:"Actinomycosis",children:[{type:"question",id:"jh0_df",label:"Choose an alternative antibiotic for patients with a history of severe penicillin allergy.",children:[]}]},{type:"article",id:"Tf06l2/Y30nSf",label:"Pilonidal disease",children:[{type:"question",id:"Kg0Uw2",label:"Recognize acute pilonidal disease, and choose the most appropriate next step in management.",children:[]}]},{type:"article",id:"Tf06l2/HR0Kof",label:"Shingles",children:[{type:"question",id:"yR0dpf",label:"Recognize shingles infection, and recall the mechanism of viral reactivation.",children:[]},{type:"question",id:"Zi0ZJf",label:"Recognize herpes zoster in an immunocompromised patient, and choose the most appropriate management.",children:[]},{type:"question",id:"DB011i",label:"Recognize shingles in an immunocompromised patient, and recall the histopathologic findings.",children:[]},{type:"question",id:"PA0WPi",label:"Recognize shingles (herpes zoster), and recall its complications.",children:[]},{type:"question",id:"BCaz85",label:"Recognize herpes zoster, and choose the most appropriate next step in management for high-risk patients.",children:[]}]},{type:"article",id:"Tf06l2/RQ0lDf",label:"Occupational skin diseases",children:[{type:"question",id:"fGakAN",label:"Recognize irritant contact dermatitis.",children:[]}]},{type:"article",id:"Tf06l2/oj00YT",label:"Glomus tumors",children:[{type:"question",id:"4B03ai",label:"Recognize a glomus tumor, and recall its cell of origin.",children:[]}]},{type:"article",id:"Tf06l2/Hj0KbT",label:"Epistaxis",children:[{type:"question",id:"kK0mgS",label:"Recognize hereditary hemorrhagic telangiectasia, and recall its cardiac 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it.",children:[]}]},{type:"article",id:"Tf06l2/k60mOS",label:"Adipose tissue",children:[{type:"question",id:"QgauEP",label:"Recall the function of thermogenin in brown adipose tissue.",children:[]}]},{type:"article",id:"Tf06l2/J60sNS",label:"The somatosensory system",children:[{type:"question",id:"8JaODl",label:"Recall the function and location of Pacinian corpuscles.",children:[]}]},{type:"article",id:"Tf06l2/hp0c6S",label:"Aging changes",children:[{type:"question",id:"DDa1g5",label:"Recognize senile purpura as a normal aging process.",children:[]},{type:"question",id:"qAaCkM",label:"Recall the clinical course of senile purpura.",children:[]}]},{type:"article",id:"Tf06l2/Mq0M_S",label:"Decubitus ulcers",children:[{type:"question",id:"uGapam",label:"Recognize a stage 2 decubitus ulcer, and choose the most appropriate wound care management.",children:[]},{type:"question",id:"BGazYm",label:"Recognize impaired microcirculation in decubitus ulcer 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patient.",children:[]},{type:"question",id:"tvaXb5",label:"Recognize adhesive capsulitis (frozen shoulder), and choose the most appropriate initial treatment.",children:[]}]},{type:"article",id:"ff0kl2/gQ0Fvf",label:"Biceps tendinopathy and biceps tendon rupture",children:[{type:"question",id:"ixaJw5",label:"Recognize distal biceps tendon rupture, and choose the most appropriate management for an active patient.",children:[]}]},{type:"article",id:"ff0kl2/hQ0cDf",label:"Dupuytren contracture",children:[{type:"question",id:"TN060g",label:"Recognize Dupuytren contracture, and recall its underlying mechanism.",children:[]}]},{type:"article",id:"ff0kl2/3Q0SDf",label:"Noninfectious tenosynovitis",children:[{type:"question",id:"xC0E8R",label:"Recognize De Quervain tenosynovitis.",children:[]}]},{type:"article",id:"ff0kl2/QQ0uDf",label:"Thoracic outlet syndrome",children:[{type:"question",id:"3raSSN",label:"Recognize a cervical rib causing thoracic outlet 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