ngoto-bio 1.2.9.9001

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Files changed (424) hide show
  1. data/ChangeLog +2046 -0
  2. data/README.rdoc +223 -0
  3. data/README_DEV.rdoc +285 -0
  4. data/Rakefile +70 -0
  5. data/bin/bioruby +44 -0
  6. data/bin/br_biofetch.rb +47 -0
  7. data/bin/br_bioflat.rb +293 -0
  8. data/bin/br_biogetseq.rb +45 -0
  9. data/bin/br_pmfetch.rb +421 -0
  10. data/bioruby.gemspec +463 -0
  11. data/bioruby.gemspec.erb +79 -0
  12. data/doc/Changes-0.7.rd +369 -0
  13. data/doc/Changes-1.3.rdoc +195 -0
  14. data/doc/KEGG_API.rd +1843 -0
  15. data/doc/KEGG_API.rd.ja +1834 -0
  16. data/doc/Tutorial.rd +1296 -0
  17. data/doc/Tutorial.rd.ja +2640 -0
  18. data/etc/bioinformatics/seqdatabase.ini +210 -0
  19. data/extconf.rb +2 -0
  20. data/lib/bio/alignment.rb +2518 -0
  21. data/lib/bio/appl/bl2seq/report.rb +334 -0
  22. data/lib/bio/appl/blast/ddbj.rb +142 -0
  23. data/lib/bio/appl/blast/format0.rb +1438 -0
  24. data/lib/bio/appl/blast/format8.rb +83 -0
  25. data/lib/bio/appl/blast/genomenet.rb +263 -0
  26. data/lib/bio/appl/blast/ncbioptions.rb +220 -0
  27. data/lib/bio/appl/blast/remote.rb +105 -0
  28. data/lib/bio/appl/blast/report.rb +767 -0
  29. data/lib/bio/appl/blast/rexml.rb +144 -0
  30. data/lib/bio/appl/blast/rpsblast.rb +277 -0
  31. data/lib/bio/appl/blast/wublast.rb +671 -0
  32. data/lib/bio/appl/blast/xmlparser.rb +236 -0
  33. data/lib/bio/appl/blast.rb +505 -0
  34. data/lib/bio/appl/blat/report.rb +530 -0
  35. data/lib/bio/appl/clustalw/report.rb +152 -0
  36. data/lib/bio/appl/clustalw.rb +219 -0
  37. data/lib/bio/appl/emboss.rb +203 -0
  38. data/lib/bio/appl/fasta/format10.rb +325 -0
  39. data/lib/bio/appl/fasta.rb +235 -0
  40. data/lib/bio/appl/gcg/msf.rb +212 -0
  41. data/lib/bio/appl/gcg/seq.rb +195 -0
  42. data/lib/bio/appl/genscan/report.rb +552 -0
  43. data/lib/bio/appl/hmmer/report.rb +683 -0
  44. data/lib/bio/appl/hmmer.rb +126 -0
  45. data/lib/bio/appl/iprscan/report.rb +374 -0
  46. data/lib/bio/appl/mafft/report.rb +226 -0
  47. data/lib/bio/appl/mafft.rb +259 -0
  48. data/lib/bio/appl/muscle.rb +52 -0
  49. data/lib/bio/appl/paml/baseml/report.rb +32 -0
  50. data/lib/bio/appl/paml/baseml.rb +95 -0
  51. data/lib/bio/appl/paml/codeml/rates.rb +67 -0
  52. data/lib/bio/appl/paml/codeml/report.rb +67 -0
  53. data/lib/bio/appl/paml/codeml.rb +242 -0
  54. data/lib/bio/appl/paml/common.rb +348 -0
  55. data/lib/bio/appl/paml/common_report.rb +38 -0
  56. data/lib/bio/appl/paml/yn00/report.rb +32 -0
  57. data/lib/bio/appl/paml/yn00.rb +103 -0
  58. data/lib/bio/appl/phylip/alignment.rb +129 -0
  59. data/lib/bio/appl/phylip/distance_matrix.rb +96 -0
  60. data/lib/bio/appl/probcons.rb +41 -0
  61. data/lib/bio/appl/psort/report.rb +457 -0
  62. data/lib/bio/appl/psort.rb +548 -0
  63. data/lib/bio/appl/pts1.rb +263 -0
  64. data/lib/bio/appl/sim4/report.rb +485 -0
  65. data/lib/bio/appl/sim4.rb +124 -0
  66. data/lib/bio/appl/sosui/report.rb +151 -0
  67. data/lib/bio/appl/spidey/report.rb +593 -0
  68. data/lib/bio/appl/targetp/report.rb +267 -0
  69. data/lib/bio/appl/tcoffee.rb +55 -0
  70. data/lib/bio/appl/tmhmm/report.rb +231 -0
  71. data/lib/bio/command.rb +593 -0
  72. data/lib/bio/compat/features.rb +157 -0
  73. data/lib/bio/compat/references.rb +128 -0
  74. data/lib/bio/data/aa.rb +349 -0
  75. data/lib/bio/data/codontable.rb +722 -0
  76. data/lib/bio/data/na.rb +223 -0
  77. data/lib/bio/db/aaindex.rb +357 -0
  78. data/lib/bio/db/biosql/biosql_to_biosequence.rb +67 -0
  79. data/lib/bio/db/biosql/sequence.rb +508 -0
  80. data/lib/bio/db/embl/common.rb +352 -0
  81. data/lib/bio/db/embl/embl.rb +500 -0
  82. data/lib/bio/db/embl/embl_to_biosequence.rb +85 -0
  83. data/lib/bio/db/embl/format_embl.rb +190 -0
  84. data/lib/bio/db/embl/sptr.rb +1283 -0
  85. data/lib/bio/db/embl/swissprot.rb +42 -0
  86. data/lib/bio/db/embl/trembl.rb +41 -0
  87. data/lib/bio/db/embl/uniprot.rb +42 -0
  88. data/lib/bio/db/fantom.rb +597 -0
  89. data/lib/bio/db/fasta/defline.rb +532 -0
  90. data/lib/bio/db/fasta/fasta_to_biosequence.rb +63 -0
  91. data/lib/bio/db/fasta/format_fasta.rb +97 -0
  92. data/lib/bio/db/fasta.rb +410 -0
  93. data/lib/bio/db/genbank/common.rb +307 -0
  94. data/lib/bio/db/genbank/ddbj.rb +22 -0
  95. data/lib/bio/db/genbank/format_genbank.rb +187 -0
  96. data/lib/bio/db/genbank/genbank.rb +250 -0
  97. data/lib/bio/db/genbank/genbank_to_biosequence.rb +86 -0
  98. data/lib/bio/db/genbank/genpept.rb +60 -0
  99. data/lib/bio/db/genbank/refseq.rb +18 -0
  100. data/lib/bio/db/gff.rb +1846 -0
  101. data/lib/bio/db/go.rb +481 -0
  102. data/lib/bio/db/kegg/brite.rb +41 -0
  103. data/lib/bio/db/kegg/compound.rb +131 -0
  104. data/lib/bio/db/kegg/drug.rb +98 -0
  105. data/lib/bio/db/kegg/enzyme.rb +148 -0
  106. data/lib/bio/db/kegg/expression.rb +155 -0
  107. data/lib/bio/db/kegg/genes.rb +263 -0
  108. data/lib/bio/db/kegg/genome.rb +241 -0
  109. data/lib/bio/db/kegg/glycan.rb +166 -0
  110. data/lib/bio/db/kegg/keggtab.rb +357 -0
  111. data/lib/bio/db/kegg/kgml.rb +256 -0
  112. data/lib/bio/db/kegg/orthology.rb +136 -0
  113. data/lib/bio/db/kegg/reaction.rb +82 -0
  114. data/lib/bio/db/kegg/taxonomy.rb +331 -0
  115. data/lib/bio/db/lasergene.rb +209 -0
  116. data/lib/bio/db/litdb.rb +107 -0
  117. data/lib/bio/db/medline.rb +326 -0
  118. data/lib/bio/db/nbrf.rb +191 -0
  119. data/lib/bio/db/newick.rb +658 -0
  120. data/lib/bio/db/nexus.rb +1854 -0
  121. data/lib/bio/db/pdb/atom.rb +77 -0
  122. data/lib/bio/db/pdb/chain.rb +210 -0
  123. data/lib/bio/db/pdb/chemicalcomponent.rb +224 -0
  124. data/lib/bio/db/pdb/model.rb +148 -0
  125. data/lib/bio/db/pdb/pdb.rb +1911 -0
  126. data/lib/bio/db/pdb/residue.rb +176 -0
  127. data/lib/bio/db/pdb/utils.rb +399 -0
  128. data/lib/bio/db/pdb.rb +29 -0
  129. data/lib/bio/db/prosite.rb +597 -0
  130. data/lib/bio/db/rebase.rb +456 -0
  131. data/lib/bio/db/soft.rb +404 -0
  132. data/lib/bio/db/transfac.rb +375 -0
  133. data/lib/bio/db.rb +329 -0
  134. data/lib/bio/feature.rb +139 -0
  135. data/lib/bio/io/biosql/biodatabase.rb +64 -0
  136. data/lib/bio/io/biosql/bioentry.rb +29 -0
  137. data/lib/bio/io/biosql/bioentry_dbxref.rb +11 -0
  138. data/lib/bio/io/biosql/bioentry_path.rb +12 -0
  139. data/lib/bio/io/biosql/bioentry_qualifier_value.rb +10 -0
  140. data/lib/bio/io/biosql/bioentry_reference.rb +10 -0
  141. data/lib/bio/io/biosql/bioentry_relationship.rb +10 -0
  142. data/lib/bio/io/biosql/biosequence.rb +11 -0
  143. data/lib/bio/io/biosql/comment.rb +7 -0
  144. data/lib/bio/io/biosql/config/database.yml +20 -0
  145. data/lib/bio/io/biosql/dbxref.rb +13 -0
  146. data/lib/bio/io/biosql/dbxref_qualifier_value.rb +12 -0
  147. data/lib/bio/io/biosql/location.rb +32 -0
  148. data/lib/bio/io/biosql/location_qualifier_value.rb +11 -0
  149. data/lib/bio/io/biosql/ontology.rb +10 -0
  150. data/lib/bio/io/biosql/reference.rb +9 -0
  151. data/lib/bio/io/biosql/seqfeature.rb +32 -0
  152. data/lib/bio/io/biosql/seqfeature_dbxref.rb +11 -0
  153. data/lib/bio/io/biosql/seqfeature_path.rb +11 -0
  154. data/lib/bio/io/biosql/seqfeature_qualifier_value.rb +20 -0
  155. data/lib/bio/io/biosql/seqfeature_relationship.rb +11 -0
  156. data/lib/bio/io/biosql/taxon.rb +12 -0
  157. data/lib/bio/io/biosql/taxon_name.rb +9 -0
  158. data/lib/bio/io/biosql/term.rb +27 -0
  159. data/lib/bio/io/biosql/term_dbxref.rb +11 -0
  160. data/lib/bio/io/biosql/term_path.rb +12 -0
  161. data/lib/bio/io/biosql/term_relationship.rb +13 -0
  162. data/lib/bio/io/biosql/term_relationship_term.rb +11 -0
  163. data/lib/bio/io/biosql/term_synonym.rb +10 -0
  164. data/lib/bio/io/das.rb +461 -0
  165. data/lib/bio/io/dbget.rb +194 -0
  166. data/lib/bio/io/ddbjxml.rb +638 -0
  167. data/lib/bio/io/ebisoap.rb +158 -0
  168. data/lib/bio/io/ensembl.rb +229 -0
  169. data/lib/bio/io/fastacmd.rb +163 -0
  170. data/lib/bio/io/fetch.rb +195 -0
  171. data/lib/bio/io/flatfile/autodetection.rb +545 -0
  172. data/lib/bio/io/flatfile/bdb.rb +253 -0
  173. data/lib/bio/io/flatfile/buffer.rb +237 -0
  174. data/lib/bio/io/flatfile/index.rb +1381 -0
  175. data/lib/bio/io/flatfile/indexer.rb +805 -0
  176. data/lib/bio/io/flatfile/splitter.rb +297 -0
  177. data/lib/bio/io/flatfile.rb +473 -0
  178. data/lib/bio/io/higet.rb +73 -0
  179. data/lib/bio/io/hinv.rb +442 -0
  180. data/lib/bio/io/keggapi.rb +805 -0
  181. data/lib/bio/io/ncbirest.rb +733 -0
  182. data/lib/bio/io/ncbisoap.rb +155 -0
  183. data/lib/bio/io/pubmed.rb +307 -0
  184. data/lib/bio/io/registry.rb +292 -0
  185. data/lib/bio/io/soapwsdl.rb +119 -0
  186. data/lib/bio/io/sql.rb +186 -0
  187. data/lib/bio/location.rb +867 -0
  188. data/lib/bio/map.rb +410 -0
  189. data/lib/bio/pathway.rb +960 -0
  190. data/lib/bio/reference.rb +602 -0
  191. data/lib/bio/sequence/aa.rb +125 -0
  192. data/lib/bio/sequence/adapter.rb +108 -0
  193. data/lib/bio/sequence/common.rb +310 -0
  194. data/lib/bio/sequence/compat.rb +123 -0
  195. data/lib/bio/sequence/dblink.rb +54 -0
  196. data/lib/bio/sequence/format.rb +358 -0
  197. data/lib/bio/sequence/format_raw.rb +23 -0
  198. data/lib/bio/sequence/generic.rb +24 -0
  199. data/lib/bio/sequence/na.rb +491 -0
  200. data/lib/bio/sequence.rb +456 -0
  201. data/lib/bio/shell/core.rb +578 -0
  202. data/lib/bio/shell/demo.rb +146 -0
  203. data/lib/bio/shell/interface.rb +218 -0
  204. data/lib/bio/shell/irb.rb +95 -0
  205. data/lib/bio/shell/object.rb +71 -0
  206. data/lib/bio/shell/plugin/blast.rb +42 -0
  207. data/lib/bio/shell/plugin/codon.rb +218 -0
  208. data/lib/bio/shell/plugin/das.rb +58 -0
  209. data/lib/bio/shell/plugin/emboss.rb +23 -0
  210. data/lib/bio/shell/plugin/entry.rb +105 -0
  211. data/lib/bio/shell/plugin/flatfile.rb +101 -0
  212. data/lib/bio/shell/plugin/keggapi.rb +181 -0
  213. data/lib/bio/shell/plugin/midi.rb +430 -0
  214. data/lib/bio/shell/plugin/obda.rb +45 -0
  215. data/lib/bio/shell/plugin/psort.rb +56 -0
  216. data/lib/bio/shell/plugin/seq.rb +247 -0
  217. data/lib/bio/shell/plugin/soap.rb +87 -0
  218. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/bioruby_generator.rb +29 -0
  219. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/_classes.rhtml +4 -0
  220. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/_log.rhtml +27 -0
  221. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/_methods.rhtml +11 -0
  222. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/_modules.rhtml +4 -0
  223. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/_variables.rhtml +7 -0
  224. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby-bg.gif +0 -0
  225. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby-gem.png +0 -0
  226. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby-link.gif +0 -0
  227. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby.css +368 -0
  228. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby.rhtml +47 -0
  229. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby_controller.rb +144 -0
  230. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby_helper.rb +47 -0
  231. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/commands.rhtml +8 -0
  232. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/history.rhtml +10 -0
  233. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/index.rhtml +26 -0
  234. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/spinner.gif +0 -0
  235. data/lib/bio/shell/script.rb +25 -0
  236. data/lib/bio/shell/setup.rb +109 -0
  237. data/lib/bio/shell/web.rb +102 -0
  238. data/lib/bio/shell.rb +44 -0
  239. data/lib/bio/tree.rb +852 -0
  240. data/lib/bio/util/color_scheme/buried.rb +59 -0
  241. data/lib/bio/util/color_scheme/helix.rb +59 -0
  242. data/lib/bio/util/color_scheme/hydropathy.rb +64 -0
  243. data/lib/bio/util/color_scheme/nucleotide.rb +31 -0
  244. data/lib/bio/util/color_scheme/strand.rb +59 -0
  245. data/lib/bio/util/color_scheme/taylor.rb +50 -0
  246. data/lib/bio/util/color_scheme/turn.rb +59 -0
  247. data/lib/bio/util/color_scheme/zappo.rb +50 -0
  248. data/lib/bio/util/color_scheme.rb +191 -0
  249. data/lib/bio/util/contingency_table.rb +370 -0
  250. data/lib/bio/util/restriction_enzyme/analysis.rb +249 -0
  251. data/lib/bio/util/restriction_enzyme/analysis_basic.rb +217 -0
  252. data/lib/bio/util/restriction_enzyme/cut_symbol.rb +107 -0
  253. data/lib/bio/util/restriction_enzyme/double_stranded/aligned_strands.rb +130 -0
  254. data/lib/bio/util/restriction_enzyme/double_stranded/cut_location_pair.rb +103 -0
  255. data/lib/bio/util/restriction_enzyme/double_stranded/cut_location_pair_in_enzyme_notation.rb +38 -0
  256. data/lib/bio/util/restriction_enzyme/double_stranded/cut_locations.rb +76 -0
  257. data/lib/bio/util/restriction_enzyme/double_stranded/cut_locations_in_enzyme_notation.rb +107 -0
  258. data/lib/bio/util/restriction_enzyme/double_stranded.rb +321 -0
  259. data/lib/bio/util/restriction_enzyme/enzymes.yaml +7061 -0
  260. data/lib/bio/util/restriction_enzyme/range/cut_range.rb +24 -0
  261. data/lib/bio/util/restriction_enzyme/range/cut_ranges.rb +47 -0
  262. data/lib/bio/util/restriction_enzyme/range/horizontal_cut_range.rb +67 -0
  263. data/lib/bio/util/restriction_enzyme/range/sequence_range/calculated_cuts.rb +242 -0
  264. data/lib/bio/util/restriction_enzyme/range/sequence_range/fragment.rb +51 -0
  265. data/lib/bio/util/restriction_enzyme/range/sequence_range/fragments.rb +41 -0
  266. data/lib/bio/util/restriction_enzyme/range/sequence_range.rb +257 -0
  267. data/lib/bio/util/restriction_enzyme/range/vertical_cut_range.rb +77 -0
  268. data/lib/bio/util/restriction_enzyme/single_strand/cut_locations_in_enzyme_notation.rb +135 -0
  269. data/lib/bio/util/restriction_enzyme/single_strand.rb +200 -0
  270. data/lib/bio/util/restriction_enzyme/single_strand_complement.rb +23 -0
  271. data/lib/bio/util/restriction_enzyme/string_formatting.rb +111 -0
  272. data/lib/bio/util/restriction_enzyme.rb +228 -0
  273. data/lib/bio/util/sirna.rb +288 -0
  274. data/lib/bio.rb +300 -0
  275. data/rdoc.zsh +8 -0
  276. data/sample/any2fasta.rb +59 -0
  277. data/sample/biofetch.rb +475 -0
  278. data/sample/color_scheme_na.rb +91 -0
  279. data/sample/dbget +37 -0
  280. data/sample/demo_sequence.rb +158 -0
  281. data/sample/enzymes.rb +78 -0
  282. data/sample/fasta2tab.rb +99 -0
  283. data/sample/fastagrep.rb +72 -0
  284. data/sample/fastasort.rb +54 -0
  285. data/sample/fsplit.rb +51 -0
  286. data/sample/gb2fasta.rb +30 -0
  287. data/sample/gb2tab.rb +325 -0
  288. data/sample/gbtab2mysql.rb +161 -0
  289. data/sample/genes2nuc.rb +33 -0
  290. data/sample/genes2pep.rb +33 -0
  291. data/sample/genes2tab.rb +81 -0
  292. data/sample/genome2rb.rb +29 -0
  293. data/sample/genome2tab.rb +76 -0
  294. data/sample/goslim.rb +303 -0
  295. data/sample/gt2fasta.rb +47 -0
  296. data/sample/na2aa.rb +34 -0
  297. data/sample/pmfetch.rb +42 -0
  298. data/sample/pmsearch.rb +42 -0
  299. data/sample/psortplot_html.rb +214 -0
  300. data/sample/ssearch2tab.rb +96 -0
  301. data/sample/tdiary.rb +158 -0
  302. data/sample/tfastx2tab.rb +100 -0
  303. data/sample/vs-genes.rb +212 -0
  304. data/setup.rb +1596 -0
  305. data/test/data/HMMER/hmmpfam.out +64 -0
  306. data/test/data/HMMER/hmmsearch.out +88 -0
  307. data/test/data/SOSUI/sample.report +11 -0
  308. data/test/data/TMHMM/sample.report +21 -0
  309. data/test/data/aaindex/DAYM780301 +30 -0
  310. data/test/data/aaindex/PRAM900102 +20 -0
  311. data/test/data/bl2seq/cd8a_cd8b_blastp.bl2seq +53 -0
  312. data/test/data/bl2seq/cd8a_p53_e-5blastp.bl2seq +37 -0
  313. data/test/data/blast/2.2.15.blastp.m7 +876 -0
  314. data/test/data/blast/b0002.faa +15 -0
  315. data/test/data/blast/b0002.faa.m0 +128 -0
  316. data/test/data/blast/b0002.faa.m7 +65 -0
  317. data/test/data/blast/b0002.faa.m8 +1 -0
  318. data/test/data/blast/blastp-multi.m7 +188 -0
  319. data/test/data/command/echoarg2.bat +1 -0
  320. data/test/data/embl/AB090716.embl +65 -0
  321. data/test/data/embl/AB090716.embl.rel89 +63 -0
  322. data/test/data/fasta/example1.txt +75 -0
  323. data/test/data/fasta/example2.txt +21 -0
  324. data/test/data/genscan/sample.report +63 -0
  325. data/test/data/iprscan/merged.raw +32 -0
  326. data/test/data/iprscan/merged.txt +74 -0
  327. data/test/data/paml/codeml/control_file.txt +30 -0
  328. data/test/data/paml/codeml/output.txt +78 -0
  329. data/test/data/paml/codeml/rates +217 -0
  330. data/test/data/prosite/prosite.dat +2233 -0
  331. data/test/data/refseq/nm_126355.entret +64 -0
  332. data/test/data/rpsblast/misc.rpsblast +193 -0
  333. data/test/data/soft/GDS100_partial.soft +92 -0
  334. data/test/data/soft/GSE3457_family_partial.soft +874 -0
  335. data/test/data/uniprot/p53_human.uniprot +1456 -0
  336. data/test/functional/bio/appl/test_pts1.rb +115 -0
  337. data/test/functional/bio/io/test_ensembl.rb +229 -0
  338. data/test/functional/bio/io/test_soapwsdl.rb +52 -0
  339. data/test/functional/bio/sequence/test_output_embl.rb +51 -0
  340. data/test/functional/bio/test_command.rb +301 -0
  341. data/test/runner.rb +23 -0
  342. data/test/unit/bio/appl/bl2seq/test_report.rb +134 -0
  343. data/test/unit/bio/appl/blast/test_ncbioptions.rb +112 -0
  344. data/test/unit/bio/appl/blast/test_report.rb +1135 -0
  345. data/test/unit/bio/appl/blast/test_rpsblast.rb +398 -0
  346. data/test/unit/bio/appl/genscan/test_report.rb +182 -0
  347. data/test/unit/bio/appl/hmmer/test_report.rb +342 -0
  348. data/test/unit/bio/appl/iprscan/test_report.rb +338 -0
  349. data/test/unit/bio/appl/mafft/test_report.rb +63 -0
  350. data/test/unit/bio/appl/paml/codeml/test_rates.rb +45 -0
  351. data/test/unit/bio/appl/paml/codeml/test_report.rb +45 -0
  352. data/test/unit/bio/appl/paml/test_codeml.rb +174 -0
  353. data/test/unit/bio/appl/sosui/test_report.rb +81 -0
  354. data/test/unit/bio/appl/targetp/test_report.rb +146 -0
  355. data/test/unit/bio/appl/test_blast.rb +277 -0
  356. data/test/unit/bio/appl/test_fasta.rb +130 -0
  357. data/test/unit/bio/appl/test_pts1.rb +77 -0
  358. data/test/unit/bio/appl/tmhmm/test_report.rb +126 -0
  359. data/test/unit/bio/data/test_aa.rb +90 -0
  360. data/test/unit/bio/data/test_codontable.rb +107 -0
  361. data/test/unit/bio/data/test_na.rb +80 -0
  362. data/test/unit/bio/db/embl/test_common.rb +117 -0
  363. data/test/unit/bio/db/embl/test_embl.rb +214 -0
  364. data/test/unit/bio/db/embl/test_embl_rel89.rb +219 -0
  365. data/test/unit/bio/db/embl/test_embl_to_bioseq.rb +203 -0
  366. data/test/unit/bio/db/embl/test_sptr.rb +1812 -0
  367. data/test/unit/bio/db/embl/test_uniprot.rb +31 -0
  368. data/test/unit/bio/db/kegg/test_genes.rb +45 -0
  369. data/test/unit/bio/db/pdb/test_pdb.rb +152 -0
  370. data/test/unit/bio/db/test_aaindex.rb +197 -0
  371. data/test/unit/bio/db/test_fasta.rb +250 -0
  372. data/test/unit/bio/db/test_gff.rb +1190 -0
  373. data/test/unit/bio/db/test_lasergene.rb +95 -0
  374. data/test/unit/bio/db/test_medline.rb +127 -0
  375. data/test/unit/bio/db/test_newick.rb +293 -0
  376. data/test/unit/bio/db/test_nexus.rb +364 -0
  377. data/test/unit/bio/db/test_prosite.rb +1437 -0
  378. data/test/unit/bio/db/test_rebase.rb +101 -0
  379. data/test/unit/bio/db/test_soft.rb +138 -0
  380. data/test/unit/bio/io/flatfile/test_autodetection.rb +375 -0
  381. data/test/unit/bio/io/flatfile/test_buffer.rb +251 -0
  382. data/test/unit/bio/io/flatfile/test_splitter.rb +369 -0
  383. data/test/unit/bio/io/test_ddbjxml.rb +80 -0
  384. data/test/unit/bio/io/test_ensembl.rb +109 -0
  385. data/test/unit/bio/io/test_fastacmd.rb +42 -0
  386. data/test/unit/bio/io/test_flatfile.rb +488 -0
  387. data/test/unit/bio/io/test_soapwsdl.rb +32 -0
  388. data/test/unit/bio/sequence/test_aa.rb +103 -0
  389. data/test/unit/bio/sequence/test_common.rb +373 -0
  390. data/test/unit/bio/sequence/test_compat.rb +69 -0
  391. data/test/unit/bio/sequence/test_dblink.rb +58 -0
  392. data/test/unit/bio/sequence/test_na.rb +330 -0
  393. data/test/unit/bio/shell/plugin/test_seq.rb +185 -0
  394. data/test/unit/bio/test_alignment.rb +1025 -0
  395. data/test/unit/bio/test_command.rb +349 -0
  396. data/test/unit/bio/test_db.rb +96 -0
  397. data/test/unit/bio/test_feature.rb +144 -0
  398. data/test/unit/bio/test_location.rb +599 -0
  399. data/test/unit/bio/test_map.rb +230 -0
  400. data/test/unit/bio/test_pathway.rb +499 -0
  401. data/test/unit/bio/test_reference.rb +252 -0
  402. data/test/unit/bio/test_sequence.rb +329 -0
  403. data/test/unit/bio/test_shell.rb +18 -0
  404. data/test/unit/bio/test_tree.rb +593 -0
  405. data/test/unit/bio/util/restriction_enzyme/analysis/test_calculated_cuts.rb +299 -0
  406. data/test/unit/bio/util/restriction_enzyme/analysis/test_cut_ranges.rb +103 -0
  407. data/test/unit/bio/util/restriction_enzyme/analysis/test_sequence_range.rb +240 -0
  408. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_aligned_strands.rb +101 -0
  409. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_location_pair.rb +75 -0
  410. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_location_pair_in_enzyme_notation.rb +73 -0
  411. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_locations.rb +53 -0
  412. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_locations_in_enzyme_notation.rb +104 -0
  413. data/test/unit/bio/util/restriction_enzyme/single_strand/test_cut_locations_in_enzyme_notation.rb +83 -0
  414. data/test/unit/bio/util/restriction_enzyme/test_analysis.rb +246 -0
  415. data/test/unit/bio/util/restriction_enzyme/test_cut_symbol.rb +44 -0
  416. data/test/unit/bio/util/restriction_enzyme/test_double_stranded.rb +115 -0
  417. data/test/unit/bio/util/restriction_enzyme/test_single_strand.rb +147 -0
  418. data/test/unit/bio/util/restriction_enzyme/test_single_strand_complement.rb +147 -0
  419. data/test/unit/bio/util/restriction_enzyme/test_string_formatting.rb +60 -0
  420. data/test/unit/bio/util/test_color_scheme.rb +33 -0
  421. data/test/unit/bio/util/test_contingency_table.rb +94 -0
  422. data/test/unit/bio/util/test_restriction_enzyme.rb +42 -0
  423. data/test/unit/bio/util/test_sirna.rb +245 -0
  424. metadata +484 -0
data/lib/bio/map.rb ADDED
@@ -0,0 +1,410 @@
1
+ #
2
+ # = bio/map.rb - biological mapping class
3
+ #
4
+ # Copyright:: Copyright (C) 2006 Jan Aerts <jan.aerts@bbsrc.ac.uk>
5
+ # License:: The Ruby License
6
+ #
7
+ # $Id: map.rb,v 1.11 2007/04/12 12:19:16 aerts Exp $
8
+
9
+ require 'bio/location'
10
+
11
+ module Bio
12
+
13
+ # == Description
14
+ #
15
+ # The Bio::Map contains classes that describe mapping information
16
+ # and can be used to contain linkage maps, radiation-hybrid maps,
17
+ # etc. As the same marker can be mapped to more than one map, and a
18
+ # single map typically contains more than one marker, the link
19
+ # between the markers and maps is handled by Bio::Map::Mapping
20
+ # objects. Therefore, to link a map to a marker, a Bio::Map::Mapping
21
+ # object is added to that Bio::Map. See usage below.
22
+ #
23
+ # Not only maps in the strict sense have map-like features (and
24
+ # similarly not only markers in the strict sense have marker-like
25
+ # features). For example, a microsatellite is something that can be
26
+ # mapped on a linkage map (and hence becomes a 'marker'), but a
27
+ # clone can also be mapped to a cytogenetic map. In that case, the
28
+ # clone acts as a marker and has marker-like properties. That same
29
+ # clone can also be considered a 'map' when BAC-end sequences are
30
+ # mapped to it. To reflect this flexibility, the modules
31
+ # Bio::Map::ActsLikeMap and Bio::Map::ActsLikeMarker define methods
32
+ # that are typical for maps and markers.
33
+ #
34
+ #--
35
+ # In a certain sense, a biological sequence also has map- and
36
+ # marker-like properties: things can be mapped to it at certain
37
+ # locations, and the sequence itself can be mapped to something else
38
+ # (e.g. the BAC-end sequence example above, or a BLAST-result).
39
+ #++
40
+ #
41
+ # == Usage
42
+ #
43
+ # my_marker1 = Bio::Map::Marker.new('marker1')
44
+ # my_marker2 = Bio::Map::Marker.new('marker2')
45
+ # my_marker3 = Bio::Map::Marker.new('marker3')
46
+ #
47
+ # my_map1 = Bio::Map::SimpleMap.new('RH_map_ABC (2006)', 'RH', 'cR')
48
+ # my_map2 = Bio::Map::SimpleMap.new('consensus', 'linkage', 'cM')
49
+ #
50
+ # my_map1.add_mapping_as_map(my_marker1, '17')
51
+ # my_map1.add_mapping_as_map(Bio::Map::Marker.new('marker2'), '5')
52
+ # my_marker3.add_mapping_as_marker(my_map1, '9')
53
+ #
54
+ # print "Does my_map1 contain marker3? => "
55
+ # puts my_map1.contains_marker?(my_marker3).to_s
56
+ # print "Does my_map2 contain marker3? => "
57
+ # puts my_map2.contains_marker?(my_marker3).to_s
58
+ #
59
+ # my_map1.mappings_as_map.sort.each do |mapping|
60
+ # puts [ mapping.map.name,
61
+ # mapping.marker.name,
62
+ # mapping.location.from.to_s,
63
+ # mapping.location.to.to_s ].join("\t")
64
+ # end
65
+ # puts my_map1.mappings_as_map.min.marker.name
66
+ #
67
+ # my_map2.mappings_as_map.each do |mapping|
68
+ # puts [ mapping.map.name,
69
+ # mapping.marker.name,
70
+ # mapping.location.from.to_s,
71
+ # mapping.location.to.to_s ].join("\t")
72
+ # end
73
+ #
74
+ module Map
75
+
76
+ # == Description
77
+ #
78
+ # The Bio::Map::ActsLikeMap module contains methods that are typical for
79
+ # map-like things:
80
+ #
81
+ # * add markers with their locations (through Bio::Map::Mappings)
82
+ # * check if a given marker is mapped to it,
83
+ # and can be mixed into other classes (e.g. Bio::Map::SimpleMap)
84
+ #
85
+ # Classes that include this mixin should provide an array property
86
+ # called mappings_as_map.
87
+ #
88
+ # For example:
89
+ #
90
+ # class MyMapThing
91
+ # include Bio::Map::ActsLikeMap
92
+ #
93
+ # def initialize (name)
94
+ # @name = name
95
+ # @mappings_as_maps = Array.new
96
+ # end
97
+ # attr_accessor :name, :mappings_as_map
98
+ # end
99
+ #
100
+ module ActsLikeMap
101
+
102
+ # == Description
103
+ #
104
+ # Adds a Bio::Map::Mappings object to its array of mappings.
105
+ #
106
+ # == Usage
107
+ #
108
+ # # suppose we have a Bio::Map::SimpleMap object called my_map
109
+ # my_map.add_mapping_as_map(Bio::Map::Marker.new('marker_a'), '5')
110
+ #
111
+ # ---
112
+ # *Arguments*:
113
+ # * _marker_ (required): Bio::Map::Marker object
114
+ # * _location_: location of mapping. Should be a _string_, not a _number_.
115
+ # *Returns*:: itself
116
+ def add_mapping_as_map(marker, location = nil)
117
+ unless marker.class.include?(Bio::Map::ActsLikeMarker)
118
+ raise "[Error] marker is not object that implements Bio::Map::ActsLikeMarker"
119
+ end
120
+ my_mapping = ( location.nil? ) ? Bio::Map::Mapping.new(self, marker, nil) : Bio::Map::Mapping.new(self, marker, Bio::Locations.new(location))
121
+ if ! marker.mapped_to?(self)
122
+ self.mappings_as_map.push(my_mapping)
123
+ marker.mappings_as_marker.push(my_mapping)
124
+ else
125
+ already_mapped = false
126
+ marker.positions_on(self).each do |loc|
127
+ if loc.equals?(Bio::Locations.new(location))
128
+ already_mapped = true
129
+ end
130
+ end
131
+ if ! already_mapped
132
+ self.mappings_as_map.push(my_mapping)
133
+ marker.mappings_as_marker.push(my_mapping)
134
+ end
135
+ end
136
+
137
+ return self
138
+ end
139
+
140
+ # Checks whether a Bio::Map::Marker is mapped to this
141
+ # Bio::Map::SimpleMap.
142
+ #
143
+ # ---
144
+ # *Arguments*:
145
+ # * _marker_: a Bio::Map::Marker object
146
+ # *Returns*:: true or false
147
+ def contains_marker?(marker)
148
+ unless marker.class.include?(Bio::Map::ActsLikeMarker)
149
+ raise "[Error] marker is not object that implements Bio::Map::ActsLikeMarker"
150
+ end
151
+ contains = false
152
+ self.mappings_as_map.each do |mapping|
153
+ if mapping.marker == marker
154
+ contains = true
155
+ return contains
156
+ end
157
+ end
158
+ return contains
159
+ end
160
+
161
+ end # ActsLikeMap
162
+
163
+ # == Description
164
+ #
165
+ # The Bio::Map::ActsLikeMarker module contains methods that are
166
+ # typical for marker-like things:
167
+ #
168
+ # * map it to one or more maps
169
+ # * check if it's mapped to a given map
170
+ # and can be mixed into other classes (e.g. Bio::Map::Marker)
171
+ #
172
+ # Classes that include this mixin should provide an array property
173
+ # called mappings_as_marker.
174
+ #
175
+ # For example:
176
+ #
177
+ # class MyMarkerThing
178
+ # include Bio::Map::ActsLikeMarker
179
+ #
180
+ # def initialize (name)
181
+ # @name = name
182
+ # @mappings_as_marker = Array.new
183
+ # end
184
+ # attr_accessor :name, :mappings_as_marker
185
+ # end
186
+ #
187
+ module ActsLikeMarker
188
+
189
+ # == Description
190
+ #
191
+ # Adds a Bio::Map::Mappings object to its array of mappings.
192
+ #
193
+ # == Usage
194
+ #
195
+ # # suppose we have a Bio::Map::Marker object called marker_a
196
+ # marker_a.add_mapping_as_marker(Bio::Map::SimpleMap.new('my_map'), '5')
197
+ #
198
+ # ---
199
+ # *Arguments*:
200
+ # * _map_ (required): Bio::Map::SimpleMap object
201
+ # * _location_: location of mapping. Should be a _string_, not a _number_.
202
+ # *Returns*:: itself
203
+ def add_mapping_as_marker(map, location = nil)
204
+ unless map.class.include?(Bio::Map::ActsLikeMap)
205
+ raise "[Error] map is not object that implements Bio::Map::ActsLikeMap"
206
+ end
207
+ my_mapping = (location.nil?) ? Bio::Map::Mappings.new(map, self, nil) : Bio::Map::Mapping.new(map, self, Bio::Locations.new(location))
208
+ if ! self.mapped_to?(map)
209
+ self.mappings_as_marker.push(my_mapping)
210
+ map.mappings_as_map.push(my_mapping)
211
+ else
212
+ already_mapped = false
213
+ self.positions_on(map).each do |loc|
214
+ if loc.equals?(Bio::Locations.new(location))
215
+ already_mapped = true
216
+ end
217
+ end
218
+ if ! already_mapped
219
+ self.mappings_as_marker.push(my_mapping)
220
+ map.mappings_as_map.push(my_mapping)
221
+ end
222
+ end
223
+ end
224
+
225
+ # Check whether this marker is mapped to a given Bio::Map::SimpleMap.
226
+ # ---
227
+ # *Arguments*:
228
+ # * _map_: a Bio::Map::SimpleMap object
229
+ # *Returns*:: true or false
230
+ def mapped_to?(map)
231
+ unless map.class.include?(Bio::Map::ActsLikeMap)
232
+ raise "[Error] map is not object that implements Bio::Map::ActsLikeMap"
233
+ end
234
+
235
+ mapped = false
236
+ self.mappings_as_marker.each do |mapping|
237
+ if mapping.map == map
238
+ mapped = true
239
+ return mapped
240
+ end
241
+ end
242
+
243
+ return mapped
244
+ end
245
+
246
+ # Return all positions of this marker on a given map.
247
+ # ---
248
+ # *Arguments*:
249
+ # * _map_: an object that mixes in Bio::Map::ActsLikeMap
250
+ # *Returns*:: array of Bio::Location objects
251
+ def positions_on(map)
252
+ unless map.class.include?(Bio::Map::ActsLikeMap)
253
+ raise "[Error] map is not object that implements Bio::Map::ActsLikeMap"
254
+ end
255
+
256
+ positions = Array.new
257
+ self.mappings_as_marker.each do |mapping|
258
+ if mapping.map == map
259
+ positions.push(mapping.location)
260
+ end
261
+ end
262
+
263
+ return positions
264
+ end
265
+
266
+ # Return all mappings of this marker on a given map.
267
+ # ---
268
+ # *Arguments*:
269
+ # * _map_: an object that mixes in Bio::Map::ActsLikeMap
270
+ # *Returns*:: array of Bio::Map::Mapping objects
271
+ def mappings_on(map)
272
+ unless map.class.include?(Bio::Map::ActsLikeMap)
273
+ raise "[Error] map is not object that implements Bio::Map::ActsLikeMap"
274
+ end
275
+
276
+ m = Array.new
277
+ self.mappings_as_marker.each do |mapping|
278
+ if mapping.map == map
279
+ m.push(mapping)
280
+ end
281
+ end
282
+
283
+ return m
284
+ end
285
+
286
+
287
+ end # ActsLikeMarker
288
+
289
+ # == Description
290
+ #
291
+ # Creates a new Bio::Map::Mapping object, which links Bio::Map::ActsAsMap-
292
+ # and Bio::Map::ActsAsMarker-like objects. This class is typically not
293
+ # accessed directly, but through map- or marker-like objects.
294
+ class Mapping
295
+
296
+ include Comparable
297
+
298
+ # Creates a new Bio::Map::Mapping object
299
+ # ---
300
+ # *Arguments*:
301
+ # * _map_: a Bio::Map::SimpleMap object
302
+ # * _marker_: a Bio::Map::Marker object
303
+ # * _location_: a Bio::Locations object
304
+ def initialize (map, marker, location = nil)
305
+ @map, @marker, @location = map, marker, location
306
+ end
307
+ attr_accessor :map, :marker, :location
308
+
309
+ # Compares the location of this mapping to another mapping.
310
+ # ---
311
+ # *Arguments*:
312
+ # * other_mapping: Bio::Map::Mapping object
313
+ # *Returns*::
314
+ # * 1 if self < other location
315
+ # * -1 if self > other location
316
+ # * 0 if both location are the same
317
+ # * nil if the argument is not a Bio::Location object
318
+ def <=>(other)
319
+ unless other.kind_of?(Bio::Map::Mapping)
320
+ raise "[Error] markers are not comparable"
321
+ end
322
+ unless @map.equal?(other.map)
323
+ raise "[Error] maps have to be the same"
324
+ end
325
+
326
+ return self.location[0].<=>(other.location[0])
327
+ end
328
+ end # Mapping
329
+
330
+ # == Description
331
+ #
332
+ # This class handles the essential storage of name, type and units
333
+ # of a map. It includes Bio::Map::ActsLikeMap, and therefore
334
+ # supports the methods of that module.
335
+ #
336
+ # == Usage
337
+ #
338
+ # my_map1 = Bio::Map::SimpleMap.new('RH_map_ABC (2006)', 'RH', 'cR')
339
+ # my_map1.add_marker(Bio::Map::Marker.new('marker_a', '17')
340
+ # my_map1.add_marker(Bio::Map::Marker.new('marker_b', '5')
341
+ #
342
+ class SimpleMap
343
+
344
+ include Bio::Map::ActsLikeMap
345
+
346
+ # Builds a new Bio::Map::SimpleMap object
347
+ # ---
348
+ # *Arguments*:
349
+ # * name: name of the map
350
+ # * type: type of the map (e.g. linkage, radiation_hybrid, cytogenetic, ...)
351
+ # * units: unit of the map (e.g. cM, cR, ...)
352
+ # *Returns*:: new Bio::Map::SimpleMap object
353
+ def initialize (name = nil, type = nil, length = nil, units = nil)
354
+ @name, @type, @length, @units = name, type, length, units
355
+ @mappings_as_map = Array.new
356
+ end
357
+
358
+ # Name of the map
359
+ attr_accessor :name
360
+
361
+ # Type of the map
362
+ attr_accessor :type
363
+
364
+ # Length of the map
365
+ attr_accessor :length
366
+
367
+ # Units of the map
368
+ attr_accessor :units
369
+
370
+ # Mappings
371
+ attr_accessor :mappings_as_map
372
+
373
+ end # SimpleMap
374
+
375
+ # == Description
376
+ #
377
+ # This class handles markers that are anchored to a Bio::Map::SimpleMap.
378
+ # It includes Bio::Map::ActsLikeMarker, and therefore supports the
379
+ # methods of that module.
380
+ #
381
+ # == Usage
382
+ #
383
+ # marker_a = Bio::Map::Marker.new('marker_a')
384
+ # marker_b = Bio::Map::Marker.new('marker_b')
385
+ #
386
+ class Marker
387
+
388
+ include Bio::Map::ActsLikeMarker
389
+
390
+ # Builds a new Bio::Map::Marker object
391
+ # ---
392
+ # *Arguments*:
393
+ # * name: name of the marker
394
+ # *Returns*:: new Bio::Map::Marker object
395
+ def initialize(name)
396
+ @name = name
397
+ @mappings_as_marker = Array.new
398
+ end
399
+
400
+ # Name of the marker
401
+ attr_accessor :name
402
+
403
+ # Mappings
404
+ attr_accessor :mappings_as_marker
405
+
406
+ end # Marker
407
+
408
+ end # Map
409
+
410
+ end # Bio