lemboy-google-api-client 0.9.26

data/generated/google/apis/genomics_v1.rb

@@ -0,0 +1,46 @@
+# Copyright 2015 Google Inc.
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#      http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+
+require 'google/apis/genomics_v1/service.rb'
+require 'google/apis/genomics_v1/classes.rb'
+require 'google/apis/genomics_v1/representations.rb'
+
+module Google
+  module Apis
+    # Genomics API
+    #
+    # Upload, process, query, and search Genomics data in the cloud.
+    #
+    # @see https://cloud.google.com/genomics
+    module GenomicsV1
+      VERSION = 'V1'
+      REVISION = '20170126'
+
+      # View and manage your data in Google BigQuery
+      AUTH_BIGQUERY = 'https://www.googleapis.com/auth/bigquery'
+
+      # Manage your data in Google Cloud Storage
+      AUTH_DEVSTORAGE_READ_WRITE = 'https://www.googleapis.com/auth/devstorage.read_write'
+
+      # View and manage your data across Google Cloud Platform services
+      AUTH_CLOUD_PLATFORM = 'https://www.googleapis.com/auth/cloud-platform'
+
+      # View Genomics data
+      AUTH_GENOMICS_READONLY = 'https://www.googleapis.com/auth/genomics.readonly'
+
+      # View and manage Genomics data
+      AUTH_GENOMICS = 'https://www.googleapis.com/auth/genomics'
+    end
+  end
+end

data/generated/google/apis/genomics_v1/classes.rb

@@ -0,0 +1,3477 @@
+# Copyright 2015 Google Inc.
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#      http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+
+require 'date'
+require 'google/apis/core/base_service'
+require 'google/apis/core/json_representation'
+require 'google/apis/core/hashable'
+require 'google/apis/errors'
+
+module Google
+  module Apis
+    module GenomicsV1
+      
+      # A bucket over which read coverage has been precomputed. A bucket corresponds
+      # to a specific range of the reference sequence.
+      class CoverageBucket
+        include Google::Apis::Core::Hashable
+      
+        # The average number of reads which are aligned to each individual
+        # reference base in this bucket.
+        # Corresponds to the JSON property `meanCoverage`
+        # @return [Float]
+        attr_accessor :mean_coverage
+      
+        # A 0-based half-open genomic coordinate range for search requests.
+        # Corresponds to the JSON property `range`
+        # @return [Google::Apis::GenomicsV1::Range]
+        attr_accessor :range
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @mean_coverage = args[:mean_coverage] if args.key?(:mean_coverage)
+          @range = args[:range] if args.key?(:range)
+        end
+      end
+      
+      # Describes a Compute Engine resource that is being managed by a running
+      # pipeline.
+      class ComputeEngine
+        include Google::Apis::Core::Hashable
+      
+        # The instance on which the operation is running.
+        # Corresponds to the JSON property `instanceName`
+        # @return [String]
+        attr_accessor :instance_name
+      
+        # The availability zone in which the instance resides.
+        # Corresponds to the JSON property `zone`
+        # @return [String]
+        attr_accessor :zone
+      
+        # The machine type of the instance.
+        # Corresponds to the JSON property `machineType`
+        # @return [String]
+        attr_accessor :machine_type
+      
+        # The names of the disks that were created for this pipeline.
+        # Corresponds to the JSON property `diskNames`
+        # @return [Array<String>]
+        attr_accessor :disk_names
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @instance_name = args[:instance_name] if args.key?(:instance_name)
+          @zone = args[:zone] if args.key?(:zone)
+          @machine_type = args[:machine_type] if args.key?(:machine_type)
+          @disk_names = args[:disk_names] if args.key?(:disk_names)
+        end
+      end
+      
+      # 
+      class ExternalId
+        include Google::Apis::Core::Hashable
+      
+        # The name of the source of this data.
+        # Corresponds to the JSON property `sourceName`
+        # @return [String]
+        attr_accessor :source_name
+      
+        # The id used by the source of this data.
+        # Corresponds to the JSON property `id`
+        # @return [String]
+        attr_accessor :id
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @source_name = args[:source_name] if args.key?(:source_name)
+          @id = args[:id] if args.key?(:id)
+        end
+      end
+      
+      # A reference is a canonical assembled DNA sequence, intended to act as a
+      # reference coordinate space for other genomic annotations. A single reference
+      # might represent the human chromosome 1 or mitochandrial DNA, for instance. A
+      # reference belongs to one or more reference sets.
+      # For more genomics resource definitions, see [Fundamentals of Google
+      # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
+      class Reference
+        include Google::Apis::Core::Hashable
+      
+        # ID from http://www.ncbi.nlm.nih.gov/taxonomy. For example, 9606 for human.
+        # Corresponds to the JSON property `ncbiTaxonId`
+        # @return [Fixnum]
+        attr_accessor :ncbi_taxon_id
+      
+        # The URI from which the sequence was obtained. Typically specifies a FASTA
+        # format file.
+        # Corresponds to the JSON property `sourceUri`
+        # @return [String]
+        attr_accessor :source_uri
+      
+        # The name of this reference, for example `22`.
+        # Corresponds to the JSON property `name`
+        # @return [String]
+        attr_accessor :name
+      
+        # MD5 of the upper-case sequence excluding all whitespace characters (this
+        # is equivalent to SQ:M5 in SAM). This value is represented in lower case
+        # hexadecimal format.
+        # Corresponds to the JSON property `md5checksum`
+        # @return [String]
+        attr_accessor :md5checksum
+      
+        # The server-generated reference ID, unique across all references.
+        # Corresponds to the JSON property `id`
+        # @return [String]
+        attr_accessor :id
+      
+        # The length of this reference's sequence.
+        # Corresponds to the JSON property `length`
+        # @return [String]
+        attr_accessor :length
+      
+        # All known corresponding accession IDs in INSDC (GenBank/ENA/DDBJ) ideally
+        # with a version number, for example `GCF_000001405.26`.
+        # Corresponds to the JSON property `sourceAccessions`
+        # @return [Array<String>]
+        attr_accessor :source_accessions
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @ncbi_taxon_id = args[:ncbi_taxon_id] if args.key?(:ncbi_taxon_id)
+          @source_uri = args[:source_uri] if args.key?(:source_uri)
+          @name = args[:name] if args.key?(:name)
+          @md5checksum = args[:md5checksum] if args.key?(:md5checksum)
+          @id = args[:id] if args.key?(:id)
+          @length = args[:length] if args.key?(:length)
+          @source_accessions = args[:source_accessions] if args.key?(:source_accessions)
+        end
+      end
+      
+      # Metadata describes a single piece of variant call metadata.
+      # These data include a top level key and either a single value string (value)
+      # or a list of key-value pairs (info.)
+      # Value and info are mutually exclusive.
+      class VariantSetMetadata
+        include Google::Apis::Core::Hashable
+      
+        # The number of values that can be included in a field described by this
+        # metadata.
+        # Corresponds to the JSON property `number`
+        # @return [String]
+        attr_accessor :number
+      
+        # User-provided ID field, not enforced by this API.
+        # Two or more pieces of structured metadata with identical
+        # id and key fields are considered equivalent.
+        # Corresponds to the JSON property `id`
+        # @return [String]
+        attr_accessor :id
+      
+        # The value field for simple metadata
+        # Corresponds to the JSON property `value`
+        # @return [String]
+        attr_accessor :value
+      
+        # The top-level key.
+        # Corresponds to the JSON property `key`
+        # @return [String]
+        attr_accessor :key
+      
+        # A textual description of this metadata.
+        # Corresponds to the JSON property `description`
+        # @return [String]
+        attr_accessor :description
+      
+        # Remaining structured metadata key-value pairs. This must be of the form
+        # map<string, string[]> (string key mapping to a list of string values).
+        # Corresponds to the JSON property `info`
+        # @return [Hash<String,Array<Object>>]
+        attr_accessor :info
+      
+        # The type of data. Possible types include: Integer, Float,
+        # Flag, Character, and String.
+        # Corresponds to the JSON property `type`
+        # @return [String]
+        attr_accessor :type
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @number = args[:number] if args.key?(:number)
+          @id = args[:id] if args.key?(:id)
+          @value = args[:value] if args.key?(:value)
+          @key = args[:key] if args.key?(:key)
+          @description = args[:description] if args.key?(:description)
+          @info = args[:info] if args.key?(:info)
+          @type = args[:type] if args.key?(:type)
+        end
+      end
+      
+      # The search variant sets request.
+      class SearchVariantSetsRequest
+        include Google::Apis::Core::Hashable
+      
+        # Exactly one dataset ID must be provided here. Only variant sets which
+        # belong to this dataset will be returned.
+        # Corresponds to the JSON property `datasetIds`
+        # @return [Array<String>]
+        attr_accessor :dataset_ids
+      
+        # The continuation token, which is used to page through large result sets.
+        # To get the next page of results, set this parameter to the value of
+        # `nextPageToken` from the previous response.
+        # Corresponds to the JSON property `pageToken`
+        # @return [String]
+        attr_accessor :page_token
+      
+        # The maximum number of results to return in a single page. If unspecified,
+        # defaults to 1024.
+        # Corresponds to the JSON property `pageSize`
+        # @return [Fixnum]
+        attr_accessor :page_size
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @dataset_ids = args[:dataset_ids] if args.key?(:dataset_ids)
+          @page_token = args[:page_token] if args.key?(:page_token)
+          @page_size = args[:page_size] if args.key?(:page_size)
+        end
+      end
+      
+      # 
+      class SearchReferenceSetsRequest
+        include Google::Apis::Core::Hashable
+      
+        # If present, return reference sets for which a substring of their
+        # `assemblyId` matches this string (case insensitive).
+        # Corresponds to the JSON property `assemblyId`
+        # @return [String]
+        attr_accessor :assembly_id
+      
+        # If present, return reference sets for which the
+        # md5checksum matches exactly.
+        # Corresponds to the JSON property `md5checksums`
+        # @return [Array<String>]
+        attr_accessor :md5checksums
+      
+        # If present, return reference sets for which a prefix of any of
+        # sourceAccessions
+        # match any of these strings. Accession numbers typically have a main number
+        # and a version, for example `NC_000001.11`.
+        # Corresponds to the JSON property `accessions`
+        # @return [Array<String>]
+        attr_accessor :accessions
+      
+        # The continuation token, which is used to page through large result sets.
+        # To get the next page of results, set this parameter to the value of
+        # `nextPageToken` from the previous response.
+        # Corresponds to the JSON property `pageToken`
+        # @return [String]
+        attr_accessor :page_token
+      
+        # The maximum number of results to return in a single page. If unspecified,
+        # defaults to 1024. The maximum value is 4096.
+        # Corresponds to the JSON property `pageSize`
+        # @return [Fixnum]
+        attr_accessor :page_size
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @assembly_id = args[:assembly_id] if args.key?(:assembly_id)
+          @md5checksums = args[:md5checksums] if args.key?(:md5checksums)
+          @accessions = args[:accessions] if args.key?(:accessions)
+          @page_token = args[:page_token] if args.key?(:page_token)
+          @page_size = args[:page_size] if args.key?(:page_size)
+        end
+      end
+      
+      # Request message for `SetIamPolicy` method.
+      class SetIamPolicyRequest
+        include Google::Apis::Core::Hashable
+      
+        # Defines an Identity and Access Management (IAM) policy. It is used to
+        # specify access control policies for Cloud Platform resources.
+        # A `Policy` consists of a list of `bindings`. A `Binding` binds a list of
+        # `members` to a `role`, where the members can be user accounts, Google groups,
+        # Google domains, and service accounts. A `role` is a named list of permissions
+        # defined by IAM.
+        # **Example**
+        # `
+        # "bindings": [
+        # `
+        # "role": "roles/owner",
+        # "members": [
+        # "user:mike@example.com",
+        # "group:admins@example.com",
+        # "domain:google.com",
+        # "serviceAccount:my-other-app@appspot.gserviceaccount.com",
+        # ]
+        # `,
+        # `
+        # "role": "roles/viewer",
+        # "members": ["user:sean@example.com"]
+        # `
+        # ]
+        # `
+        # For a description of IAM and its features, see the
+        # [IAM developer's guide](https://cloud.google.com/iam).
+        # Corresponds to the JSON property `policy`
+        # @return [Google::Apis::GenomicsV1::Policy]
+        attr_accessor :policy
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @policy = args[:policy] if args.key?(:policy)
+        end
+      end
+      
+      # 
+      class MergeVariantsRequest
+        include Google::Apis::Core::Hashable
+      
+        # A mapping between info field keys and the InfoMergeOperations to
+        # be performed on them.
+        # Corresponds to the JSON property `infoMergeConfig`
+        # @return [Hash<String,String>]
+        attr_accessor :info_merge_config
+      
+        # The destination variant set.
+        # Corresponds to the JSON property `variantSetId`
+        # @return [String]
+        attr_accessor :variant_set_id
+      
+        # The variants to be merged with existing variants.
+        # Corresponds to the JSON property `variants`
+        # @return [Array<Google::Apis::GenomicsV1::Variant>]
+        attr_accessor :variants
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @info_merge_config = args[:info_merge_config] if args.key?(:info_merge_config)
+          @variant_set_id = args[:variant_set_id] if args.key?(:variant_set_id)
+          @variants = args[:variants] if args.key?(:variants)
+        end
+      end
+      
+      # 
+      class BatchCreateAnnotationsRequest
+        include Google::Apis::Core::Hashable
+      
+        # The annotations to be created. At most 4096 can be specified in a single
+        # request.
+        # Corresponds to the JSON property `annotations`
+        # @return [Array<Google::Apis::GenomicsV1::Annotation>]
+        attr_accessor :annotations
+      
+        # A unique request ID which enables the server to detect duplicated requests.
+        # If provided, duplicated requests will result in the same response; if not
+        # provided, duplicated requests may result in duplicated data. For a given
+        # annotation set, callers should not reuse `request_id`s when writing
+        # different batches of annotations - behavior in this case is undefined.
+        # A common approach is to use a UUID. For batch jobs where worker crashes are
+        # a possibility, consider using some unique variant of a worker or run ID.
+        # Corresponds to the JSON property `requestId`
+        # @return [String]
+        attr_accessor :request_id
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @annotations = args[:annotations] if args.key?(:annotations)
+          @request_id = args[:request_id] if args.key?(:request_id)
+        end
+      end
+      
+      # A read alignment describes a linear alignment of a string of DNA to a
+      # reference sequence, in addition to metadata
+      # about the fragment (the molecule of DNA sequenced) and the read (the bases
+      # which were read by the sequencer). A read is equivalent to a line in a SAM
+      # file. A read belongs to exactly one read group and exactly one
+      # read group set.
+      # For more genomics resource definitions, see [Fundamentals of Google
+      # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
+      # ### Reverse-stranded reads
+      # Mapped reads (reads having a non-null `alignment`) can be aligned to either
+      # the forward or the reverse strand of their associated reference. Strandedness
+      # of a mapped read is encoded by `alignment.position.reverseStrand`.
+      # If we consider the reference to be a forward-stranded coordinate space of
+      # `[0, reference.length)` with `0` as the left-most position and
+      # `reference.length` as the right-most position, reads are always aligned left
+      # to right. That is, `alignment.position.position` always refers to the
+      # left-most reference coordinate and `alignment.cigar` describes the alignment
+      # of this read to the reference from left to right. All per-base fields such as
+      # `alignedSequence` and `alignedQuality` share this same left-to-right
+      # orientation; this is true of reads which are aligned to either strand. For
+      # reverse-stranded reads, this means that `alignedSequence` is the reverse
+      # complement of the bases that were originally reported by the sequencing
+      # machine.
+      # ### Generating a reference-aligned sequence string
+      # When interacting with mapped reads, it's often useful to produce a string
+      # representing the local alignment of the read to reference. The following
+      # pseudocode demonstrates one way of doing this:
+      # out = ""
+      # offset = 0
+      # for c in read.alignment.cigar `
+      # switch c.operation `
+      # case "ALIGNMENT_MATCH", "SEQUENCE_MATCH", "SEQUENCE_MISMATCH":
+      # out += read.alignedSequence[offset:offset+c.operationLength]
+      # offset += c.operationLength
+      # break
+      # case "CLIP_SOFT", "INSERT":
+      # offset += c.operationLength
+      # break
+      # case "PAD":
+      # out += repeat("*", c.operationLength)
+      # break
+      # case "DELETE":
+      # out += repeat("-", c.operationLength)
+      # break
+      # case "SKIP":
+      # out += repeat(" ", c.operationLength)
+      # break
+      # case "CLIP_HARD":
+      # break
+      # `
+      # `
+      # return out
+      # ### Converting to SAM's CIGAR string
+      # The following pseudocode generates a SAM CIGAR string from the
+      # `cigar` field. Note that this is a lossy conversion
+      # (`cigar.referenceSequence` is lost).
+      # cigarMap = `
+      # "ALIGNMENT_MATCH": "M",
+      # "INSERT": "I",
+      # "DELETE": "D",
+      # "SKIP": "N",
+      # "CLIP_SOFT": "S",
+      # "CLIP_HARD": "H",
+      # "PAD": "P",
+      # "SEQUENCE_MATCH": "=",
+      # "SEQUENCE_MISMATCH": "X",
+      # `
+      # cigarStr = ""
+      # for c in read.alignment.cigar `
+      # cigarStr += c.operationLength + cigarMap[c.operation]
+      # `
+      # return cigarStr
+      class Read
+        include Google::Apis::Core::Hashable
+      
+        # The fragment is a PCR or optical duplicate (SAM flag 0x400).
+        # Corresponds to the JSON property `duplicateFragment`
+        # @return [Boolean]
+        attr_accessor :duplicate_fragment
+        alias_method :duplicate_fragment?, :duplicate_fragment
+      
+        # The read number in sequencing. 0-based and less than numberReads. This
+        # field replaces SAM flag 0x40 and 0x80.
+        # Corresponds to the JSON property `readNumber`
+        # @return [Fixnum]
+        attr_accessor :read_number
+      
+        # The ID of the read group this read belongs to. A read belongs to exactly
+        # one read group. This is a server-generated ID which is distinct from SAM's
+        # RG tag (for that value, see
+        # ReadGroup.name).
+        # Corresponds to the JSON property `readGroupId`
+        # @return [String]
+        attr_accessor :read_group_id
+      
+        # The bases of the read sequence contained in this alignment record,
+        # **without CIGAR operations applied** (equivalent to SEQ in SAM).
+        # `alignedSequence` and `alignedQuality` may be
+        # shorter than the full read sequence and quality. This will occur if the
+        # alignment is part of a chimeric alignment, or if the read was trimmed. When
+        # this occurs, the CIGAR for this read will begin/end with a hard clip
+        # operator that will indicate the length of the excised sequence.
+        # Corresponds to the JSON property `alignedSequence`
+        # @return [String]
+        attr_accessor :aligned_sequence
+      
+        # A map of additional read alignment information. This must be of the form
+        # map<string, string[]> (string key mapping to a list of string values).
+        # Corresponds to the JSON property `info`
+        # @return [Hash<String,Array<Object>>]
+        attr_accessor :info
+      
+        # An abstraction for referring to a genomic position, in relation to some
+        # already known reference. For now, represents a genomic position as a
+        # reference name, a base number on that reference (0-based), and a
+        # determination of forward or reverse strand.
+        # Corresponds to the JSON property `nextMatePosition`
+        # @return [Google::Apis::GenomicsV1::Position]
+        attr_accessor :next_mate_position
+      
+        # Whether this alignment is supplementary. Equivalent to SAM flag 0x800.
+        # Supplementary alignments are used in the representation of a chimeric
+        # alignment. In a chimeric alignment, a read is split into multiple
+        # linear alignments that map to different reference contigs. The first
+        # linear alignment in the read will be designated as the representative
+        # alignment; the remaining linear alignments will be designated as
+        # supplementary alignments. These alignments may have different mapping
+        # quality scores. In each linear alignment in a chimeric alignment, the read
+        # will be hard clipped. The `alignedSequence` and
+        # `alignedQuality` fields in the alignment record will only
+        # represent the bases for its respective linear alignment.
+        # Corresponds to the JSON property `supplementaryAlignment`
+        # @return [Boolean]
+        attr_accessor :supplementary_alignment
+        alias_method :supplementary_alignment?, :supplementary_alignment
+      
+        # The orientation and the distance between reads from the fragment are
+        # consistent with the sequencing protocol (SAM flag 0x2).
+        # Corresponds to the JSON property `properPlacement`
+        # @return [Boolean]
+        attr_accessor :proper_placement
+        alias_method :proper_placement?, :proper_placement
+      
+        # The observed length of the fragment, equivalent to TLEN in SAM.
+        # Corresponds to the JSON property `fragmentLength`
+        # @return [Fixnum]
+        attr_accessor :fragment_length
+      
+        # Whether this read did not pass filters, such as platform or vendor quality
+        # controls (SAM flag 0x200).
+        # Corresponds to the JSON property `failedVendorQualityChecks`
+        # @return [Boolean]
+        attr_accessor :failed_vendor_quality_checks
+        alias_method :failed_vendor_quality_checks?, :failed_vendor_quality_checks
+      
+        # The quality of the read sequence contained in this alignment record
+        # (equivalent to QUAL in SAM).
+        # `alignedSequence` and `alignedQuality` may be shorter than the full read
+        # sequence and quality. This will occur if the alignment is part of a
+        # chimeric alignment, or if the read was trimmed. When this occurs, the CIGAR
+        # for this read will begin/end with a hard clip operator that will indicate
+        # the length of the excised sequence.
+        # Corresponds to the JSON property `alignedQuality`
+        # @return [Array<Fixnum>]
+        attr_accessor :aligned_quality
+      
+        # A linear alignment can be represented by one CIGAR string. Describes the
+        # mapped position and local alignment of the read to the reference.
+        # Corresponds to the JSON property `alignment`
+        # @return [Google::Apis::GenomicsV1::LinearAlignment]
+        attr_accessor :alignment
+      
+        # The number of reads in the fragment (extension to SAM flag 0x1).
+        # Corresponds to the JSON property `numberReads`
+        # @return [Fixnum]
+        attr_accessor :number_reads
+      
+        # The server-generated read ID, unique across all reads. This is different
+        # from the `fragmentName`.
+        # Corresponds to the JSON property `id`
+        # @return [String]
+        attr_accessor :id
+      
+        # Whether this alignment is secondary. Equivalent to SAM flag 0x100.
+        # A secondary alignment represents an alternative to the primary alignment
+        # for this read. Aligners may return secondary alignments if a read can map
+        # ambiguously to multiple coordinates in the genome. By convention, each read
+        # has one and only one alignment where both `secondaryAlignment`
+        # and `supplementaryAlignment` are false.
+        # Corresponds to the JSON property `secondaryAlignment`
+        # @return [Boolean]
+        attr_accessor :secondary_alignment
+        alias_method :secondary_alignment?, :secondary_alignment
+      
+        # The fragment name. Equivalent to QNAME (query template name) in SAM.
+        # Corresponds to the JSON property `fragmentName`
+        # @return [String]
+        attr_accessor :fragment_name
+      
+        # The ID of the read group set this read belongs to. A read belongs to
+        # exactly one read group set.
+        # Corresponds to the JSON property `readGroupSetId`
+        # @return [String]
+        attr_accessor :read_group_set_id
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @duplicate_fragment = args[:duplicate_fragment] if args.key?(:duplicate_fragment)
+          @read_number = args[:read_number] if args.key?(:read_number)
+          @read_group_id = args[:read_group_id] if args.key?(:read_group_id)
+          @aligned_sequence = args[:aligned_sequence] if args.key?(:aligned_sequence)
+          @info = args[:info] if args.key?(:info)
+          @next_mate_position = args[:next_mate_position] if args.key?(:next_mate_position)
+          @supplementary_alignment = args[:supplementary_alignment] if args.key?(:supplementary_alignment)
+          @proper_placement = args[:proper_placement] if args.key?(:proper_placement)
+          @fragment_length = args[:fragment_length] if args.key?(:fragment_length)
+          @failed_vendor_quality_checks = args[:failed_vendor_quality_checks] if args.key?(:failed_vendor_quality_checks)
+          @aligned_quality = args[:aligned_quality] if args.key?(:aligned_quality)
+          @alignment = args[:alignment] if args.key?(:alignment)
+          @number_reads = args[:number_reads] if args.key?(:number_reads)
+          @id = args[:id] if args.key?(:id)
+          @secondary_alignment = args[:secondary_alignment] if args.key?(:secondary_alignment)
+          @fragment_name = args[:fragment_name] if args.key?(:fragment_name)
+          @read_group_set_id = args[:read_group_set_id] if args.key?(:read_group_set_id)
+        end
+      end
+      
+      # A reference set is a set of references which typically comprise a reference
+      # assembly for a species, such as `GRCh38` which is representative
+      # of the human genome. A reference set defines a common coordinate space for
+      # comparing reference-aligned experimental data. A reference set contains 1 or
+      # more references.
+      # For more genomics resource definitions, see [Fundamentals of Google
+      # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
+      class ReferenceSet
+        include Google::Apis::Core::Hashable
+      
+        # All known corresponding accession IDs in INSDC (GenBank/ENA/DDBJ) ideally
+        # with a version number, for example `NC_000001.11`.
+        # Corresponds to the JSON property `sourceAccessions`
+        # @return [Array<String>]
+        attr_accessor :source_accessions
+      
+        # Free text description of this reference set.
+        # Corresponds to the JSON property `description`
+        # @return [String]
+        attr_accessor :description
+      
+        # The URI from which the references were obtained.
+        # Corresponds to the JSON property `sourceUri`
+        # @return [String]
+        attr_accessor :source_uri
+      
+        # ID from http://www.ncbi.nlm.nih.gov/taxonomy (for example, 9606 for human)
+        # indicating the species which this reference set is intended to model. Note
+        # that contained references may specify a different `ncbiTaxonId`, as
+        # assemblies may contain reference sequences which do not belong to the
+        # modeled species, for example EBV in a human reference genome.
+        # Corresponds to the JSON property `ncbiTaxonId`
+        # @return [Fixnum]
+        attr_accessor :ncbi_taxon_id
+      
+        # The IDs of the reference objects that are part of this set.
+        # `Reference.md5checksum` must be unique within this set.
+        # Corresponds to the JSON property `referenceIds`
+        # @return [Array<String>]
+        attr_accessor :reference_ids
+      
+        # Public id of this reference set, such as `GRCh37`.
+        # Corresponds to the JSON property `assemblyId`
+        # @return [String]
+        attr_accessor :assembly_id
+      
+        # Order-independent MD5 checksum which identifies this reference set. The
+        # checksum is computed by sorting all lower case hexidecimal string
+        # `reference.md5checksum` (for all reference in this set) in
+        # ascending lexicographic order, concatenating, and taking the MD5 of that
+        # value. The resulting value is represented in lower case hexadecimal format.
+        # Corresponds to the JSON property `md5checksum`
+        # @return [String]
+        attr_accessor :md5checksum
+      
+        # The server-generated reference set ID, unique across all reference sets.
+        # Corresponds to the JSON property `id`
+        # @return [String]
+        attr_accessor :id
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @source_accessions = args[:source_accessions] if args.key?(:source_accessions)
+          @description = args[:description] if args.key?(:description)
+          @source_uri = args[:source_uri] if args.key?(:source_uri)
+          @ncbi_taxon_id = args[:ncbi_taxon_id] if args.key?(:ncbi_taxon_id)
+          @reference_ids = args[:reference_ids] if args.key?(:reference_ids)
+          @assembly_id = args[:assembly_id] if args.key?(:assembly_id)
+          @md5checksum = args[:md5checksum] if args.key?(:md5checksum)
+          @id = args[:id] if args.key?(:id)
+        end
+      end
+      
+      # A single CIGAR operation.
+      class CigarUnit
+        include Google::Apis::Core::Hashable
+      
+        # `referenceSequence` is only used at mismatches
+        # (`SEQUENCE_MISMATCH`) and deletions (`DELETE`).
+        # Filling this field replaces SAM's MD tag. If the relevant information is
+        # not available, this field is unset.
+        # Corresponds to the JSON property `referenceSequence`
+        # @return [String]
+        attr_accessor :reference_sequence
+      
+        # The number of genomic bases that the operation runs for. Required.
+        # Corresponds to the JSON property `operationLength`
+        # @return [String]
+        attr_accessor :operation_length
+      
+        # 
+        # Corresponds to the JSON property `operation`
+        # @return [String]
+        attr_accessor :operation
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @reference_sequence = args[:reference_sequence] if args.key?(:reference_sequence)
+          @operation_length = args[:operation_length] if args.key?(:operation_length)
+          @operation = args[:operation] if args.key?(:operation)
+        end
+      end
+      
+      # An annotation set is a logical grouping of annotations that share consistent
+      # type information and provenance. Examples of annotation sets include 'all
+      # genes from refseq', and 'all variant annotations from ClinVar'.
+      class AnnotationSet
+        include Google::Apis::Core::Hashable
+      
+        # The dataset to which this annotation set belongs.
+        # Corresponds to the JSON property `datasetId`
+        # @return [String]
+        attr_accessor :dataset_id
+      
+        # The source URI describing the file from which this annotation set was
+        # generated, if any.
+        # Corresponds to the JSON property `sourceUri`
+        # @return [String]
+        attr_accessor :source_uri
+      
+        # The display name for this annotation set.
+        # Corresponds to the JSON property `name`
+        # @return [String]
+        attr_accessor :name
+      
+        # The ID of the reference set that defines the coordinate space for this
+        # set's annotations.
+        # Corresponds to the JSON property `referenceSetId`
+        # @return [String]
+        attr_accessor :reference_set_id
+      
+        # A map of additional read alignment information. This must be of the form
+        # map<string, string[]> (string key mapping to a list of string values).
+        # Corresponds to the JSON property `info`
+        # @return [Hash<String,Array<Object>>]
+        attr_accessor :info
+      
+        # The type of annotations contained within this set.
+        # Corresponds to the JSON property `type`
+        # @return [String]
+        attr_accessor :type
+      
+        # The server-generated annotation set ID, unique across all annotation sets.
+        # Corresponds to the JSON property `id`
+        # @return [String]
+        attr_accessor :id
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @dataset_id = args[:dataset_id] if args.key?(:dataset_id)
+          @source_uri = args[:source_uri] if args.key?(:source_uri)
+          @name = args[:name] if args.key?(:name)
+          @reference_set_id = args[:reference_set_id] if args.key?(:reference_set_id)
+          @info = args[:info] if args.key?(:info)
+          @type = args[:type] if args.key?(:type)
+          @id = args[:id] if args.key?(:id)
+        end
+      end
+      
+      # A transcript represents the assertion that a particular region of the
+      # reference genome may be transcribed as RNA.
+      class Transcript
+        include Google::Apis::Core::Hashable
+      
+        # The <a href="http://en.wikipedia.org/wiki/Exon">exons</a> that compose
+        # this transcript. This field should be unset for genomes where transcript
+        # splicing does not occur, for example prokaryotes.
+        # Introns are regions of the transcript that are not included in the
+        # spliced RNA product. Though not explicitly modeled here, intron ranges can
+        # be deduced; all regions of this transcript that are not exons are introns.
+        # Exonic sequences do not necessarily code for a translational product
+        # (amino acids). Only the regions of exons bounded by the
+        # codingSequence correspond
+        # to coding DNA sequence.
+        # Exons are ordered by start position and may not overlap.
+        # Corresponds to the JSON property `exons`
+        # @return [Array<Google::Apis::GenomicsV1::Exon>]
+        attr_accessor :exons
+      
+        # The range of the coding sequence for this transcript, if any. To determine
+        # the exact ranges of coding sequence, intersect this range with those of the
+        # exons, if any. If there are any
+        # exons, the
+        # codingSequence must start
+        # and end within them.
+        # Note that in some cases, the reference genome will not exactly match the
+        # observed mRNA transcript e.g. due to variance in the source genome from
+        # reference. In these cases,
+        # exon.frame will not necessarily
+        # match the expected reference reading frame and coding exon reference bases
+        # cannot necessarily be concatenated to produce the original transcript mRNA.
+        # Corresponds to the JSON property `codingSequence`
+        # @return [Google::Apis::GenomicsV1::CodingSequence]
+        attr_accessor :coding_sequence
+      
+        # The annotation ID of the gene from which this transcript is transcribed.
+        # Corresponds to the JSON property `geneId`
+        # @return [String]
+        attr_accessor :gene_id
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @exons = args[:exons] if args.key?(:exons)
+          @coding_sequence = args[:coding_sequence] if args.key?(:coding_sequence)
+          @gene_id = args[:gene_id] if args.key?(:gene_id)
+        end
+      end
+      
+      # 
+      class Experiment
+        include Google::Apis::Core::Hashable
+      
+        # The platform unit used as part of this experiment, for example
+        # flowcell-barcode.lane for Illumina or slide for SOLiD. Corresponds to the
+        # @RG PU field in the SAM spec.
+        # Corresponds to the JSON property `platformUnit`
+        # @return [String]
+        attr_accessor :platform_unit
+      
+        # A client-supplied library identifier; a library is a collection of DNA
+        # fragments which have been prepared for sequencing from a sample. This
+        # field is important for quality control as error or bias can be introduced
+        # during sample preparation.
+        # Corresponds to the JSON property `libraryId`
+        # @return [String]
+        attr_accessor :library_id
+      
+        # The instrument model used as part of this experiment. This maps to
+        # sequencing technology in the SAM spec.
+        # Corresponds to the JSON property `instrumentModel`
+        # @return [String]
+        attr_accessor :instrument_model
+      
+        # The sequencing center used as part of this experiment.
+        # Corresponds to the JSON property `sequencingCenter`
+        # @return [String]
+        attr_accessor :sequencing_center
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @platform_unit = args[:platform_unit] if args.key?(:platform_unit)
+          @library_id = args[:library_id] if args.key?(:library_id)
+          @instrument_model = args[:instrument_model] if args.key?(:instrument_model)
+          @sequencing_center = args[:sequencing_center] if args.key?(:sequencing_center)
+        end
+      end
+      
+      # The dataset list response.
+      class ListDatasetsResponse
+        include Google::Apis::Core::Hashable
+      
+        # The list of matching Datasets.
+        # Corresponds to the JSON property `datasets`
+        # @return [Array<Google::Apis::GenomicsV1::Dataset>]
+        attr_accessor :datasets
+      
+        # The continuation token, which is used to page through large result sets.
+        # Provide this value in a subsequent request to return the next page of
+        # results. This field will be empty if there aren't any additional results.
+        # Corresponds to the JSON property `nextPageToken`
+        # @return [String]
+        attr_accessor :next_page_token
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @datasets = args[:datasets] if args.key?(:datasets)
+          @next_page_token = args[:next_page_token] if args.key?(:next_page_token)
+        end
+      end
+      
+      # Request message for `TestIamPermissions` method.
+      class TestIamPermissionsRequest
+        include Google::Apis::Core::Hashable
+      
+        # REQUIRED: The set of permissions to check for the 'resource'.
+        # Permissions with wildcards (such as '*' or 'storage.*') are not allowed.
+        # Allowed permissions are&#58;
+        # * `genomics.datasets.create`
+        # * `genomics.datasets.delete`
+        # * `genomics.datasets.get`
+        # * `genomics.datasets.list`
+        # * `genomics.datasets.update`
+        # * `genomics.datasets.getIamPolicy`
+        # * `genomics.datasets.setIamPolicy`
+        # Corresponds to the JSON property `permissions`
+        # @return [Array<String>]
+        attr_accessor :permissions
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @permissions = args[:permissions] if args.key?(:permissions)
+        end
+      end
+      
+      # The read group set export request.
+      class ExportReadGroupSetRequest
+        include Google::Apis::Core::Hashable
+      
+        # Required. A Google Cloud Storage URI for the exported BAM file.
+        # The currently authenticated user must have write access to the new file.
+        # An error will be returned if the URI already contains data.
+        # Corresponds to the JSON property `exportUri`
+        # @return [String]
+        attr_accessor :export_uri
+      
+        # The reference names to export. If this is not specified, all reference
+        # sequences, including unmapped reads, are exported.
+        # Use `*` to export only unmapped reads.
+        # Corresponds to the JSON property `referenceNames`
+        # @return [Array<String>]
+        attr_accessor :reference_names
+      
+        # Required. The Google Cloud project ID that owns this
+        # export. The caller must have WRITE access to this project.
+        # Corresponds to the JSON property `projectId`
+        # @return [String]
+        attr_accessor :project_id
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @export_uri = args[:export_uri] if args.key?(:export_uri)
+          @reference_names = args[:reference_names] if args.key?(:reference_names)
+          @project_id = args[:project_id] if args.key?(:project_id)
+        end
+      end
+      
+      # 
+      class Exon
+        include Google::Apis::Core::Hashable
+      
+        # The start position of the exon on this annotation's reference sequence,
+        # 0-based inclusive. Note that this is relative to the reference start, and
+        # **not** the containing annotation start.
+        # Corresponds to the JSON property `start`
+        # @return [String]
+        attr_accessor :start
+      
+        # The end position of the exon on this annotation's reference sequence,
+        # 0-based exclusive. Note that this is relative to the reference start, and
+        # *not* the containing annotation start.
+        # Corresponds to the JSON property `end`
+        # @return [String]
+        attr_accessor :end
+      
+        # The frame of this exon. Contains a value of 0, 1, or 2, which indicates
+        # the offset of the first coding base of the exon within the reading frame
+        # of the coding DNA sequence, if any. This field is dependent on the
+        # strandedness of this annotation (see
+        # Annotation.reverse_strand).
+        # For forward stranded annotations, this offset is relative to the
+        # exon.start. For reverse
+        # strand annotations, this offset is relative to the
+        # exon.end `- 1`.
+        # Unset if this exon does not intersect the coding sequence. Upon creation
+        # of a transcript, the frame must be populated for all or none of the
+        # coding exons.
+        # Corresponds to the JSON property `frame`
+        # @return [Fixnum]
+        attr_accessor :frame
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @start = args[:start] if args.key?(:start)
+          @end = args[:end] if args.key?(:end)
+          @frame = args[:frame] if args.key?(:frame)
+        end
+      end
+      
+      # A call set is a collection of variant calls, typically for one sample. It
+      # belongs to a variant set.
+      # For more genomics resource definitions, see [Fundamentals of Google
+      # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
+      class CallSet
+        include Google::Apis::Core::Hashable
+      
+        # The date this call set was created in milliseconds from the epoch.
+        # Corresponds to the JSON property `created`
+        # @return [String]
+        attr_accessor :created
+      
+        # The sample ID this call set corresponds to.
+        # Corresponds to the JSON property `sampleId`
+        # @return [String]
+        attr_accessor :sample_id
+      
+        # The call set name.
+        # Corresponds to the JSON property `name`
+        # @return [String]
+        attr_accessor :name
+      
+        # A map of additional call set information. This must be of the form
+        # map<string, string[]> (string key mapping to a list of string values).
+        # Corresponds to the JSON property `info`
+        # @return [Hash<String,Array<Object>>]
+        attr_accessor :info
+      
+        # The IDs of the variant sets this call set belongs to. This field must
+        # have exactly length one, as a call set belongs to a single variant set.
+        # This field is repeated for compatibility with the
+        # [GA4GH 0.5.1
+        # API](https://github.com/ga4gh/schemas/blob/v0.5.1/src/main/resources/avro/
+        # variants.avdl#L76).
+        # Corresponds to the JSON property `variantSetIds`
+        # @return [Array<String>]
+        attr_accessor :variant_set_ids
+      
+        # The server-generated call set ID, unique across all call sets.
+        # Corresponds to the JSON property `id`
+        # @return [String]
+        attr_accessor :id
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @created = args[:created] if args.key?(:created)
+          @sample_id = args[:sample_id] if args.key?(:sample_id)
+          @name = args[:name] if args.key?(:name)
+          @info = args[:info] if args.key?(:info)
+          @variant_set_ids = args[:variant_set_ids] if args.key?(:variant_set_ids)
+          @id = args[:id] if args.key?(:id)
+        end
+      end
+      
+      # 
+      class SearchAnnotationSetsResponse
+        include Google::Apis::Core::Hashable
+      
+        # The matching annotation sets.
+        # Corresponds to the JSON property `annotationSets`
+        # @return [Array<Google::Apis::GenomicsV1::AnnotationSet>]
+        attr_accessor :annotation_sets
+      
+        # The continuation token, which is used to page through large result sets.
+        # Provide this value in a subsequent request to return the next page of
+        # results. This field will be empty if there aren't any additional results.
+        # Corresponds to the JSON property `nextPageToken`
+        # @return [String]
+        attr_accessor :next_page_token
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @annotation_sets = args[:annotation_sets] if args.key?(:annotation_sets)
+          @next_page_token = args[:next_page_token] if args.key?(:next_page_token)
+        end
+      end
+      
+      # The variant data import request.
+      class ImportVariantsRequest
+        include Google::Apis::Core::Hashable
+      
+        # A mapping between info field keys and the InfoMergeOperations to
+        # be performed on them. This is plumbed down to the MergeVariantRequests
+        # generated by the resulting import job.
+        # Corresponds to the JSON property `infoMergeConfig`
+        # @return [Hash<String,String>]
+        attr_accessor :info_merge_config
+      
+        # Required. The variant set to which variant data should be imported.
+        # Corresponds to the JSON property `variantSetId`
+        # @return [String]
+        attr_accessor :variant_set_id
+      
+        # A list of URIs referencing variant files in Google Cloud Storage. URIs can
+        # include wildcards [as described
+        # here](https://cloud.google.com/storage/docs/gsutil/addlhelp/WildcardNames).
+        # Note that recursive wildcards ('**') are not supported.
+        # Corresponds to the JSON property `sourceUris`
+        # @return [Array<String>]
+        attr_accessor :source_uris
+      
+        # Convert reference names to the canonical representation.
+        # hg19 haploytypes (those reference names containing "_hap")
+        # are not modified in any way.
+        # All other reference names are modified according to the following rules:
+        # The reference name is capitalized.
+        # The "chr" prefix is dropped for all autosomes and sex chromsomes.
+        # For example "chr17" becomes "17" and "chrX" becomes "X".
+        # All mitochondrial chromosomes ("chrM", "chrMT", etc) become "MT".
+        # Corresponds to the JSON property `normalizeReferenceNames`
+        # @return [Boolean]
+        attr_accessor :normalize_reference_names
+        alias_method :normalize_reference_names?, :normalize_reference_names
+      
+        # The format of the variant data being imported. If unspecified, defaults to
+        # to `VCF`.
+        # Corresponds to the JSON property `format`
+        # @return [String]
+        attr_accessor :format
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @info_merge_config = args[:info_merge_config] if args.key?(:info_merge_config)
+          @variant_set_id = args[:variant_set_id] if args.key?(:variant_set_id)
+          @source_uris = args[:source_uris] if args.key?(:source_uris)
+          @normalize_reference_names = args[:normalize_reference_names] if args.key?(:normalize_reference_names)
+          @format = args[:format] if args.key?(:format)
+        end
+      end
+      
+      # 
+      class VariantAnnotation
+        include Google::Apis::Core::Hashable
+      
+        # The set of conditions associated with this variant.
+        # A condition describes the way a variant influences human health.
+        # Corresponds to the JSON property `conditions`
+        # @return [Array<Google::Apis::GenomicsV1::ClinicalCondition>]
+        attr_accessor :conditions
+      
+        # Effect of the variant on the coding sequence.
+        # Corresponds to the JSON property `effect`
+        # @return [String]
+        attr_accessor :effect
+      
+        # Google annotation IDs of the transcripts affected by this variant. These
+        # should be provided when the variant is created.
+        # Corresponds to the JSON property `transcriptIds`
+        # @return [Array<String>]
+        attr_accessor :transcript_ids
+      
+        # Type has been adapted from ClinVar's list of variant types.
+        # Corresponds to the JSON property `type`
+        # @return [String]
+        attr_accessor :type
+      
+        # The alternate allele for this variant. If multiple alternate alleles
+        # exist at this location, create a separate variant for each one, as they
+        # may represent distinct conditions.
+        # Corresponds to the JSON property `alternateBases`
+        # @return [String]
+        attr_accessor :alternate_bases
+      
+        # Google annotation ID of the gene affected by this variant. This should
+        # be provided when the variant is created.
+        # Corresponds to the JSON property `geneId`
+        # @return [String]
+        attr_accessor :gene_id
+      
+        # Describes the clinical significance of a variant.
+        # It is adapted from the ClinVar controlled vocabulary for clinical
+        # significance described at:
+        # http://www.ncbi.nlm.nih.gov/clinvar/docs/clinsig/
+        # Corresponds to the JSON property `clinicalSignificance`
+        # @return [String]
+        attr_accessor :clinical_significance
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @conditions = args[:conditions] if args.key?(:conditions)
+          @effect = args[:effect] if args.key?(:effect)
+          @transcript_ids = args[:transcript_ids] if args.key?(:transcript_ids)
+          @type = args[:type] if args.key?(:type)
+          @alternate_bases = args[:alternate_bases] if args.key?(:alternate_bases)
+          @gene_id = args[:gene_id] if args.key?(:gene_id)
+          @clinical_significance = args[:clinical_significance] if args.key?(:clinical_significance)
+        end
+      end
+      
+      # 
+      class ListCoverageBucketsResponse
+        include Google::Apis::Core::Hashable
+      
+        # The length of each coverage bucket in base pairs. Note that buckets at the
+        # end of a reference sequence may be shorter. This value is omitted if the
+        # bucket width is infinity (the default behaviour, with no range or
+        # `targetBucketWidth`).
+        # Corresponds to the JSON property `bucketWidth`
+        # @return [String]
+        attr_accessor :bucket_width
+      
+        # The coverage buckets. The list of buckets is sparse; a bucket with 0
+        # overlapping reads is not returned. A bucket never crosses more than one
+        # reference sequence. Each bucket has width `bucketWidth`, unless
+        # its end is the end of the reference sequence.
+        # Corresponds to the JSON property `coverageBuckets`
+        # @return [Array<Google::Apis::GenomicsV1::CoverageBucket>]
+        attr_accessor :coverage_buckets
+      
+        # The continuation token, which is used to page through large result sets.
+        # Provide this value in a subsequent request to return the next page of
+        # results. This field will be empty if there aren't any additional results.
+        # Corresponds to the JSON property `nextPageToken`
+        # @return [String]
+        attr_accessor :next_page_token
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @bucket_width = args[:bucket_width] if args.key?(:bucket_width)
+          @coverage_buckets = args[:coverage_buckets] if args.key?(:coverage_buckets)
+          @next_page_token = args[:next_page_token] if args.key?(:next_page_token)
+        end
+      end
+      
+      # The variant data export request.
+      class ExportVariantSetRequest
+        include Google::Apis::Core::Hashable
+      
+        # The format for the exported data.
+        # Corresponds to the JSON property `format`
+        # @return [String]
+        attr_accessor :format
+      
+        # Required. The BigQuery dataset to export data to. This dataset must already
+        # exist. Note that this is distinct from the Genomics concept of "dataset".
+        # Corresponds to the JSON property `bigqueryDataset`
+        # @return [String]
+        attr_accessor :bigquery_dataset
+      
+        # Required. The BigQuery table to export data to.
+        # If the table doesn't exist, it will be created. If it already exists, it
+        # will be overwritten.
+        # Corresponds to the JSON property `bigqueryTable`
+        # @return [String]
+        attr_accessor :bigquery_table
+      
+        # If provided, only variant call information from the specified call sets
+        # will be exported. By default all variant calls are exported.
+        # Corresponds to the JSON property `callSetIds`
+        # @return [Array<String>]
+        attr_accessor :call_set_ids
+      
+        # Required. The Google Cloud project ID that owns the destination
+        # BigQuery dataset. The caller must have WRITE access to this project.  This
+        # project will also own the resulting export job.
+        # Corresponds to the JSON property `projectId`
+        # @return [String]
+        attr_accessor :project_id
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @format = args[:format] if args.key?(:format)
+          @bigquery_dataset = args[:bigquery_dataset] if args.key?(:bigquery_dataset)
+          @bigquery_table = args[:bigquery_table] if args.key?(:bigquery_table)
+          @call_set_ids = args[:call_set_ids] if args.key?(:call_set_ids)
+          @project_id = args[:project_id] if args.key?(:project_id)
+        end
+      end
+      
+      # 
+      class SearchAnnotationsRequest
+        include Google::Apis::Core::Hashable
+      
+        # The continuation token, which is used to page through large result sets.
+        # To get the next page of results, set this parameter to the value of
+        # `nextPageToken` from the previous response.
+        # Corresponds to the JSON property `pageToken`
+        # @return [String]
+        attr_accessor :page_token
+      
+        # The maximum number of results to return in a single page. If unspecified,
+        # defaults to 256. The maximum value is 2048.
+        # Corresponds to the JSON property `pageSize`
+        # @return [Fixnum]
+        attr_accessor :page_size
+      
+        # The start position of the range on the reference, 0-based inclusive. If
+        # specified,
+        # referenceId or
+        # referenceName
+        # must be specified. Defaults to 0.
+        # Corresponds to the JSON property `start`
+        # @return [String]
+        attr_accessor :start
+      
+        # Required. The annotation sets to search within. The caller must have
+        # `READ` access to these annotation sets.
+        # All queried annotation sets must have the same type.
+        # Corresponds to the JSON property `annotationSetIds`
+        # @return [Array<String>]
+        attr_accessor :annotation_set_ids
+      
+        # The name of the reference to query, within the reference set associated
+        # with this query.
+        # Corresponds to the JSON property `referenceName`
+        # @return [String]
+        attr_accessor :reference_name
+      
+        # The ID of the reference to query.
+        # Corresponds to the JSON property `referenceId`
+        # @return [String]
+        attr_accessor :reference_id
+      
+        # The end position of the range on the reference, 0-based exclusive. If
+        # referenceId or
+        # referenceName
+        # must be specified, Defaults to the length of the reference.
+        # Corresponds to the JSON property `end`
+        # @return [String]
+        attr_accessor :end
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @page_token = args[:page_token] if args.key?(:page_token)
+          @page_size = args[:page_size] if args.key?(:page_size)
+          @start = args[:start] if args.key?(:start)
+          @annotation_set_ids = args[:annotation_set_ids] if args.key?(:annotation_set_ids)
+          @reference_name = args[:reference_name] if args.key?(:reference_name)
+          @reference_id = args[:reference_id] if args.key?(:reference_id)
+          @end = args[:end] if args.key?(:end)
+        end
+      end
+      
+      # An event that occurred during an Operation.
+      class OperationEvent
+        include Google::Apis::Core::Hashable
+      
+        # Optional time of when event finished. An event can have a start time and no
+        # finish time. If an event has a finish time, there must be a start time.
+        # Corresponds to the JSON property `endTime`
+        # @return [String]
+        attr_accessor :end_time
+      
+        # Optional time of when event started.
+        # Corresponds to the JSON property `startTime`
+        # @return [String]
+        attr_accessor :start_time
+      
+        # Required description of event.
+        # Corresponds to the JSON property `description`
+        # @return [String]
+        attr_accessor :description
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @end_time = args[:end_time] if args.key?(:end_time)
+          @start_time = args[:start_time] if args.key?(:start_time)
+          @description = args[:description] if args.key?(:description)
+        end
+      end
+      
+      # 
+      class CodingSequence
+        include Google::Apis::Core::Hashable
+      
+        # The start of the coding sequence on this annotation's reference sequence,
+        # 0-based inclusive. Note that this position is relative to the reference
+        # start, and *not* the containing annotation start.
+        # Corresponds to the JSON property `start`
+        # @return [String]
+        attr_accessor :start
+      
+        # The end of the coding sequence on this annotation's reference sequence,
+        # 0-based exclusive. Note that this position is relative to the reference
+        # start, and *not* the containing annotation start.
+        # Corresponds to the JSON property `end`
+        # @return [String]
+        attr_accessor :end
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @start = args[:start] if args.key?(:start)
+          @end = args[:end] if args.key?(:end)
+        end
+      end
+      
+      # 
+      class SearchReferencesResponse
+        include Google::Apis::Core::Hashable
+      
+        # The matching references.
+        # Corresponds to the JSON property `references`
+        # @return [Array<Google::Apis::GenomicsV1::Reference>]
+        attr_accessor :references
+      
+        # The continuation token, which is used to page through large result sets.
+        # Provide this value in a subsequent request to return the next page of
+        # results. This field will be empty if there aren't any additional results.
+        # Corresponds to the JSON property `nextPageToken`
+        # @return [String]
+        attr_accessor :next_page_token
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @references = args[:references] if args.key?(:references)
+          @next_page_token = args[:next_page_token] if args.key?(:next_page_token)
+        end
+      end
+      
+      # Request message for `GetIamPolicy` method.
+      class GetIamPolicyRequest
+        include Google::Apis::Core::Hashable
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+        end
+      end
+      
+      # Response message for `TestIamPermissions` method.
+      class TestIamPermissionsResponse
+        include Google::Apis::Core::Hashable
+      
+        # A subset of `TestPermissionsRequest.permissions` that the caller is
+        # allowed.
+        # Corresponds to the JSON property `permissions`
+        # @return [Array<String>]
+        attr_accessor :permissions
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @permissions = args[:permissions] if args.key?(:permissions)
+        end
+      end
+      
+      # 
+      class SearchAnnotationSetsRequest
+        include Google::Apis::Core::Hashable
+      
+        # The continuation token, which is used to page through large result sets.
+        # To get the next page of results, set this parameter to the value of
+        # `nextPageToken` from the previous response.
+        # Corresponds to the JSON property `pageToken`
+        # @return [String]
+        attr_accessor :page_token
+      
+        # The maximum number of results to return in a single page. If unspecified,
+        # defaults to 128. The maximum value is 1024.
+        # Corresponds to the JSON property `pageSize`
+        # @return [Fixnum]
+        attr_accessor :page_size
+      
+        # Required. The dataset IDs to search within. Caller must have `READ` access
+        # to these datasets.
+        # Corresponds to the JSON property `datasetIds`
+        # @return [Array<String>]
+        attr_accessor :dataset_ids
+      
+        # If specified, only annotation sets that have any of these types are
+        # returned.
+        # Corresponds to the JSON property `types`
+        # @return [Array<String>]
+        attr_accessor :types
+      
+        # Only return annotations sets for which a substring of the name matches this
+        # string (case insensitive).
+        # Corresponds to the JSON property `name`
+        # @return [String]
+        attr_accessor :name
+      
+        # If specified, only annotation sets associated with the given reference set
+        # are returned.
+        # Corresponds to the JSON property `referenceSetId`
+        # @return [String]
+        attr_accessor :reference_set_id
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @page_token = args[:page_token] if args.key?(:page_token)
+          @page_size = args[:page_size] if args.key?(:page_size)
+          @dataset_ids = args[:dataset_ids] if args.key?(:dataset_ids)
+          @types = args[:types] if args.key?(:types)
+          @name = args[:name] if args.key?(:name)
+          @reference_set_id = args[:reference_set_id] if args.key?(:reference_set_id)
+        end
+      end
+      
+      # The read group set search response.
+      class SearchReadGroupSetsResponse
+        include Google::Apis::Core::Hashable
+      
+        # The list of matching read group sets.
+        # Corresponds to the JSON property `readGroupSets`
+        # @return [Array<Google::Apis::GenomicsV1::ReadGroupSet>]
+        attr_accessor :read_group_sets
+      
+        # The continuation token, which is used to page through large result sets.
+        # Provide this value in a subsequent request to return the next page of
+        # results. This field will be empty if there aren't any additional results.
+        # Corresponds to the JSON property `nextPageToken`
+        # @return [String]
+        attr_accessor :next_page_token
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @read_group_sets = args[:read_group_sets] if args.key?(:read_group_sets)
+          @next_page_token = args[:next_page_token] if args.key?(:next_page_token)
+        end
+      end
+      
+      # A linear alignment can be represented by one CIGAR string. Describes the
+      # mapped position and local alignment of the read to the reference.
+      class LinearAlignment
+        include Google::Apis::Core::Hashable
+      
+        # An abstraction for referring to a genomic position, in relation to some
+        # already known reference. For now, represents a genomic position as a
+        # reference name, a base number on that reference (0-based), and a
+        # determination of forward or reverse strand.
+        # Corresponds to the JSON property `position`
+        # @return [Google::Apis::GenomicsV1::Position]
+        attr_accessor :position
+      
+        # Represents the local alignment of this sequence (alignment matches, indels,
+        # etc) against the reference.
+        # Corresponds to the JSON property `cigar`
+        # @return [Array<Google::Apis::GenomicsV1::CigarUnit>]
+        attr_accessor :cigar
+      
+        # The mapping quality of this alignment. Represents how likely
+        # the read maps to this position as opposed to other locations.
+        # Specifically, this is -10 log10 Pr(mapping position is wrong), rounded to
+        # the nearest integer.
+        # Corresponds to the JSON property `mappingQuality`
+        # @return [Fixnum]
+        attr_accessor :mapping_quality
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @position = args[:position] if args.key?(:position)
+          @cigar = args[:cigar] if args.key?(:cigar)
+          @mapping_quality = args[:mapping_quality] if args.key?(:mapping_quality)
+        end
+      end
+      
+      # 
+      class SearchReferencesRequest
+        include Google::Apis::Core::Hashable
+      
+        # If present, return references for which the
+        # md5checksum matches exactly.
+        # Corresponds to the JSON property `md5checksums`
+        # @return [Array<String>]
+        attr_accessor :md5checksums
+      
+        # If present, return references for which a prefix of any of
+        # sourceAccessions match
+        # any of these strings. Accession numbers typically have a main number and a
+        # version, for example `GCF_000001405.26`.
+        # Corresponds to the JSON property `accessions`
+        # @return [Array<String>]
+        attr_accessor :accessions
+      
+        # The continuation token, which is used to page through large result sets.
+        # To get the next page of results, set this parameter to the value of
+        # `nextPageToken` from the previous response.
+        # Corresponds to the JSON property `pageToken`
+        # @return [String]
+        attr_accessor :page_token
+      
+        # If present, return only references which belong to this reference set.
+        # Corresponds to the JSON property `referenceSetId`
+        # @return [String]
+        attr_accessor :reference_set_id
+      
+        # The maximum number of results to return in a single page. If unspecified,
+        # defaults to 1024. The maximum value is 4096.
+        # Corresponds to the JSON property `pageSize`
+        # @return [Fixnum]
+        attr_accessor :page_size
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @md5checksums = args[:md5checksums] if args.key?(:md5checksums)
+          @accessions = args[:accessions] if args.key?(:accessions)
+          @page_token = args[:page_token] if args.key?(:page_token)
+          @reference_set_id = args[:reference_set_id] if args.key?(:reference_set_id)
+          @page_size = args[:page_size] if args.key?(:page_size)
+        end
+      end
+      
+      # A Dataset is a collection of genomic data.
+      # For more genomics resource definitions, see [Fundamentals of Google
+      # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
+      class Dataset
+        include Google::Apis::Core::Hashable
+      
+        # The time this dataset was created, in seconds from the epoch.
+        # Corresponds to the JSON property `createTime`
+        # @return [String]
+        attr_accessor :create_time
+      
+        # The dataset name.
+        # Corresponds to the JSON property `name`
+        # @return [String]
+        attr_accessor :name
+      
+        # The Google Cloud project ID that this dataset belongs to.
+        # Corresponds to the JSON property `projectId`
+        # @return [String]
+        attr_accessor :project_id
+      
+        # The server-generated dataset ID, unique across all datasets.
+        # Corresponds to the JSON property `id`
+        # @return [String]
+        attr_accessor :id
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @create_time = args[:create_time] if args.key?(:create_time)
+          @name = args[:name] if args.key?(:name)
+          @project_id = args[:project_id] if args.key?(:project_id)
+          @id = args[:id] if args.key?(:id)
+        end
+      end
+      
+      # The variant data import response.
+      class ImportVariantsResponse
+        include Google::Apis::Core::Hashable
+      
+        # IDs of the call sets created during the import.
+        # Corresponds to the JSON property `callSetIds`
+        # @return [Array<String>]
+        attr_accessor :call_set_ids
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @call_set_ids = args[:call_set_ids] if args.key?(:call_set_ids)
+        end
+      end
+      
+      # A read group is all the data that's processed the same way by the sequencer.
+      class ReadGroup
+        include Google::Apis::Core::Hashable
+      
+        # The reference set the reads in this read group are aligned to.
+        # Corresponds to the JSON property `referenceSetId`
+        # @return [String]
+        attr_accessor :reference_set_id
+      
+        # A map of additional read group information. This must be of the form
+        # map<string, string[]> (string key mapping to a list of string values).
+        # Corresponds to the JSON property `info`
+        # @return [Hash<String,Array<Object>>]
+        attr_accessor :info
+      
+        # The server-generated read group ID, unique for all read groups.
+        # Note: This is different than the @RG ID field in the SAM spec. For that
+        # value, see name.
+        # Corresponds to the JSON property `id`
+        # @return [String]
+        attr_accessor :id
+      
+        # The predicted insert size of this read group. The insert size is the length
+        # the sequenced DNA fragment from end-to-end, not including the adapters.
+        # Corresponds to the JSON property `predictedInsertSize`
+        # @return [Fixnum]
+        attr_accessor :predicted_insert_size
+      
+        # The programs used to generate this read group. Programs are always
+        # identical for all read groups within a read group set. For this reason,
+        # only the first read group in a returned set will have this field
+        # populated.
+        # Corresponds to the JSON property `programs`
+        # @return [Array<Google::Apis::GenomicsV1::Program>]
+        attr_accessor :programs
+      
+        # A free-form text description of this read group.
+        # Corresponds to the JSON property `description`
+        # @return [String]
+        attr_accessor :description
+      
+        # A client-supplied sample identifier for the reads in this read group.
+        # Corresponds to the JSON property `sampleId`
+        # @return [String]
+        attr_accessor :sample_id
+      
+        # The dataset to which this read group belongs.
+        # Corresponds to the JSON property `datasetId`
+        # @return [String]
+        attr_accessor :dataset_id
+      
+        # The experiment used to generate this read group.
+        # Corresponds to the JSON property `experiment`
+        # @return [Google::Apis::GenomicsV1::Experiment]
+        attr_accessor :experiment
+      
+        # The read group name. This corresponds to the @RG ID field in the SAM spec.
+        # Corresponds to the JSON property `name`
+        # @return [String]
+        attr_accessor :name
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @reference_set_id = args[:reference_set_id] if args.key?(:reference_set_id)
+          @info = args[:info] if args.key?(:info)
+          @id = args[:id] if args.key?(:id)
+          @predicted_insert_size = args[:predicted_insert_size] if args.key?(:predicted_insert_size)
+          @programs = args[:programs] if args.key?(:programs)
+          @description = args[:description] if args.key?(:description)
+          @sample_id = args[:sample_id] if args.key?(:sample_id)
+          @dataset_id = args[:dataset_id] if args.key?(:dataset_id)
+          @experiment = args[:experiment] if args.key?(:experiment)
+          @name = args[:name] if args.key?(:name)
+        end
+      end
+      
+      # A read group set is a logical collection of read groups, which are
+      # collections of reads produced by a sequencer. A read group set typically
+      # models reads corresponding to one sample, sequenced one way, and aligned one
+      # way.
+      # * A read group set belongs to one dataset.
+      # * A read group belongs to one read group set.
+      # * A read belongs to one read group.
+      # For more genomics resource definitions, see [Fundamentals of Google
+      # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
+      class ReadGroupSet
+        include Google::Apis::Core::Hashable
+      
+        # The read groups in this set. There are typically 1-10 read groups in a read
+        # group set.
+        # Corresponds to the JSON property `readGroups`
+        # @return [Array<Google::Apis::GenomicsV1::ReadGroup>]
+        attr_accessor :read_groups
+      
+        # The filename of the original source file for this read group set, if any.
+        # Corresponds to the JSON property `filename`
+        # @return [String]
+        attr_accessor :filename
+      
+        # The read group set name. By default this will be initialized to the sample
+        # name of the sequenced data contained in this set.
+        # Corresponds to the JSON property `name`
+        # @return [String]
+        attr_accessor :name
+      
+        # The reference set to which the reads in this read group set are aligned.
+        # Corresponds to the JSON property `referenceSetId`
+        # @return [String]
+        attr_accessor :reference_set_id
+      
+        # A map of additional read group set information.
+        # Corresponds to the JSON property `info`
+        # @return [Hash<String,Array<Object>>]
+        attr_accessor :info
+      
+        # The server-generated read group set ID, unique for all read group sets.
+        # Corresponds to the JSON property `id`
+        # @return [String]
+        attr_accessor :id
+      
+        # The dataset to which this read group set belongs.
+        # Corresponds to the JSON property `datasetId`
+        # @return [String]
+        attr_accessor :dataset_id
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @read_groups = args[:read_groups] if args.key?(:read_groups)
+          @filename = args[:filename] if args.key?(:filename)
+          @name = args[:name] if args.key?(:name)
+          @reference_set_id = args[:reference_set_id] if args.key?(:reference_set_id)
+          @info = args[:info] if args.key?(:info)
+          @id = args[:id] if args.key?(:id)
+          @dataset_id = args[:dataset_id] if args.key?(:dataset_id)
+        end
+      end
+      
+      # The search variant sets response.
+      class SearchVariantSetsResponse
+        include Google::Apis::Core::Hashable
+      
+        # The continuation token, which is used to page through large result sets.
+        # Provide this value in a subsequent request to return the next page of
+        # results. This field will be empty if there aren't any additional results.
+        # Corresponds to the JSON property `nextPageToken`
+        # @return [String]
+        attr_accessor :next_page_token
+      
+        # The variant sets belonging to the requested dataset.
+        # Corresponds to the JSON property `variantSets`
+        # @return [Array<Google::Apis::GenomicsV1::VariantSet>]
+        attr_accessor :variant_sets
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @next_page_token = args[:next_page_token] if args.key?(:next_page_token)
+          @variant_sets = args[:variant_sets] if args.key?(:variant_sets)
+        end
+      end
+      
+      # A generic empty message that you can re-use to avoid defining duplicated
+      # empty messages in your APIs. A typical example is to use it as the request
+      # or the response type of an API method. For instance:
+      # service Foo `
+      # rpc Bar(google.protobuf.Empty) returns (google.protobuf.Empty);
+      # `
+      # The JSON representation for `Empty` is empty JSON object ````.
+      class Empty
+        include Google::Apis::Core::Hashable
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+        end
+      end
+      
+      # 
+      class Entry
+        include Google::Apis::Core::Hashable
+      
+        # The `Status` type defines a logical error model that is suitable for different
+        # programming environments, including REST APIs and RPC APIs. It is used by
+        # [gRPC](https://github.com/grpc). The error model is designed to be:
+        # - Simple to use and understand for most users
+        # - Flexible enough to meet unexpected needs
+        # # Overview
+        # The `Status` message contains three pieces of data: error code, error message,
+        # and error details. The error code should be an enum value of
+        # google.rpc.Code, but it may accept additional error codes if needed.  The
+        # error message should be a developer-facing English message that helps
+        # developers *understand* and *resolve* the error. If a localized user-facing
+        # error message is needed, put the localized message in the error details or
+        # localize it in the client. The optional error details may contain arbitrary
+        # information about the error. There is a predefined set of error detail types
+        # in the package `google.rpc` which can be used for common error conditions.
+        # # Language mapping
+        # The `Status` message is the logical representation of the error model, but it
+        # is not necessarily the actual wire format. When the `Status` message is
+        # exposed in different client libraries and different wire protocols, it can be
+        # mapped differently. For example, it will likely be mapped to some exceptions
+        # in Java, but more likely mapped to some error codes in C.
+        # # Other uses
+        # The error model and the `Status` message can be used in a variety of
+        # environments, either with or without APIs, to provide a
+        # consistent developer experience across different environments.
+        # Example uses of this error model include:
+        # - Partial errors. If a service needs to return partial errors to the client,
+        # it may embed the `Status` in the normal response to indicate the partial
+        # errors.
+        # - Workflow errors. A typical workflow has multiple steps. Each step may
+        # have a `Status` message for error reporting purpose.
+        # - Batch operations. If a client uses batch request and batch response, the
+        # `Status` message should be used directly inside batch response, one for
+        # each error sub-response.
+        # - Asynchronous operations. If an API call embeds asynchronous operation
+        # results in its response, the status of those operations should be
+        # represented directly using the `Status` message.
+        # - Logging. If some API errors are stored in logs, the message `Status` could
+        # be used directly after any stripping needed for security/privacy reasons.
+        # Corresponds to the JSON property `status`
+        # @return [Google::Apis::GenomicsV1::Status]
+        attr_accessor :status
+      
+        # An annotation describes a region of reference genome. The value of an
+        # annotation may be one of several canonical types, supplemented by arbitrary
+        # info tags. An annotation is not inherently associated with a specific
+        # sample or individual (though a client could choose to use annotations in
+        # this way). Example canonical annotation types are `GENE` and
+        # `VARIANT`.
+        # Corresponds to the JSON property `annotation`
+        # @return [Google::Apis::GenomicsV1::Annotation]
+        attr_accessor :annotation
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @status = args[:status] if args.key?(:status)
+          @annotation = args[:annotation] if args.key?(:annotation)
+        end
+      end
+      
+      # An abstraction for referring to a genomic position, in relation to some
+      # already known reference. For now, represents a genomic position as a
+      # reference name, a base number on that reference (0-based), and a
+      # determination of forward or reverse strand.
+      class Position
+        include Google::Apis::Core::Hashable
+      
+        # Whether this position is on the reverse strand, as opposed to the forward
+        # strand.
+        # Corresponds to the JSON property `reverseStrand`
+        # @return [Boolean]
+        attr_accessor :reverse_strand
+        alias_method :reverse_strand?, :reverse_strand
+      
+        # The 0-based offset from the start of the forward strand for that reference.
+        # Corresponds to the JSON property `position`
+        # @return [String]
+        attr_accessor :position
+      
+        # The name of the reference in whatever reference set is being used.
+        # Corresponds to the JSON property `referenceName`
+        # @return [String]
+        attr_accessor :reference_name
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @reverse_strand = args[:reverse_strand] if args.key?(:reverse_strand)
+          @position = args[:position] if args.key?(:position)
+          @reference_name = args[:reference_name] if args.key?(:reference_name)
+        end
+      end
+      
+      # 
+      class SearchReferenceSetsResponse
+        include Google::Apis::Core::Hashable
+      
+        # The matching references sets.
+        # Corresponds to the JSON property `referenceSets`
+        # @return [Array<Google::Apis::GenomicsV1::ReferenceSet>]
+        attr_accessor :reference_sets
+      
+        # The continuation token, which is used to page through large result sets.
+        # Provide this value in a subsequent request to return the next page of
+        # results. This field will be empty if there aren't any additional results.
+        # Corresponds to the JSON property `nextPageToken`
+        # @return [String]
+        attr_accessor :next_page_token
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @reference_sets = args[:reference_sets] if args.key?(:reference_sets)
+          @next_page_token = args[:next_page_token] if args.key?(:next_page_token)
+        end
+      end
+      
+      # The call set search request.
+      class SearchCallSetsRequest
+        include Google::Apis::Core::Hashable
+      
+        # Restrict the query to call sets within the given variant sets. At least one
+        # ID must be provided.
+        # Corresponds to the JSON property `variantSetIds`
+        # @return [Array<String>]
+        attr_accessor :variant_set_ids
+      
+        # Only return call sets for which a substring of the name matches this
+        # string.
+        # Corresponds to the JSON property `name`
+        # @return [String]
+        attr_accessor :name
+      
+        # The continuation token, which is used to page through large result sets.
+        # To get the next page of results, set this parameter to the value of
+        # `nextPageToken` from the previous response.
+        # Corresponds to the JSON property `pageToken`
+        # @return [String]
+        attr_accessor :page_token
+      
+        # The maximum number of results to return in a single page. If unspecified,
+        # defaults to 1024.
+        # Corresponds to the JSON property `pageSize`
+        # @return [Fixnum]
+        attr_accessor :page_size
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @variant_set_ids = args[:variant_set_ids] if args.key?(:variant_set_ids)
+          @name = args[:name] if args.key?(:name)
+          @page_token = args[:page_token] if args.key?(:page_token)
+          @page_size = args[:page_size] if args.key?(:page_size)
+        end
+      end
+      
+      # The read group set import request.
+      class ImportReadGroupSetsRequest
+        include Google::Apis::Core::Hashable
+      
+        # The reference set to which the imported read group sets are aligned to, if
+        # any. The reference names of this reference set must be a superset of those
+        # found in the imported file headers. If no reference set id is provided, a
+        # best effort is made to associate with a matching reference set.
+        # Corresponds to the JSON property `referenceSetId`
+        # @return [String]
+        attr_accessor :reference_set_id
+      
+        # The partition strategy describes how read groups are partitioned into read
+        # group sets.
+        # Corresponds to the JSON property `partitionStrategy`
+        # @return [String]
+        attr_accessor :partition_strategy
+      
+        # Required. The ID of the dataset these read group sets will belong to. The
+        # caller must have WRITE permissions to this dataset.
+        # Corresponds to the JSON property `datasetId`
+        # @return [String]
+        attr_accessor :dataset_id
+      
+        # A list of URIs pointing at [BAM
+        # files](https://samtools.github.io/hts-specs/SAMv1.pdf)
+        # in Google Cloud Storage.
+        # Those URIs can include wildcards (*), but do not add or remove
+        # matching files before import has completed.
+        # Note that Google Cloud Storage object listing is only eventually
+        # consistent: files added may be not be immediately visible to
+        # everyone. Thus, if using a wildcard it is preferable not to start
+        # the import immediately after the files are created.
+        # Corresponds to the JSON property `sourceUris`
+        # @return [Array<String>]
+        attr_accessor :source_uris
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @reference_set_id = args[:reference_set_id] if args.key?(:reference_set_id)
+          @partition_strategy = args[:partition_strategy] if args.key?(:partition_strategy)
+          @dataset_id = args[:dataset_id] if args.key?(:dataset_id)
+          @source_uris = args[:source_uris] if args.key?(:source_uris)
+        end
+      end
+      
+      # Defines an Identity and Access Management (IAM) policy. It is used to
+      # specify access control policies for Cloud Platform resources.
+      # A `Policy` consists of a list of `bindings`. A `Binding` binds a list of
+      # `members` to a `role`, where the members can be user accounts, Google groups,
+      # Google domains, and service accounts. A `role` is a named list of permissions
+      # defined by IAM.
+      # **Example**
+      # `
+      # "bindings": [
+      # `
+      # "role": "roles/owner",
+      # "members": [
+      # "user:mike@example.com",
+      # "group:admins@example.com",
+      # "domain:google.com",
+      # "serviceAccount:my-other-app@appspot.gserviceaccount.com",
+      # ]
+      # `,
+      # `
+      # "role": "roles/viewer",
+      # "members": ["user:sean@example.com"]
+      # `
+      # ]
+      # `
+      # For a description of IAM and its features, see the
+      # [IAM developer's guide](https://cloud.google.com/iam).
+      class Policy
+        include Google::Apis::Core::Hashable
+      
+        # `etag` is used for optimistic concurrency control as a way to help
+        # prevent simultaneous updates of a policy from overwriting each other.
+        # It is strongly suggested that systems make use of the `etag` in the
+        # read-modify-write cycle to perform policy updates in order to avoid race
+        # conditions: An `etag` is returned in the response to `getIamPolicy`, and
+        # systems are expected to put that etag in the request to `setIamPolicy` to
+        # ensure that their change will be applied to the same version of the policy.
+        # If no `etag` is provided in the call to `setIamPolicy`, then the existing
+        # policy is overwritten blindly.
+        # Corresponds to the JSON property `etag`
+        # @return [String]
+        attr_accessor :etag
+      
+        # Version of the `Policy`. The default version is 0.
+        # Corresponds to the JSON property `version`
+        # @return [Fixnum]
+        attr_accessor :version
+      
+        # Associates a list of `members` to a `role`.
+        # Multiple `bindings` must not be specified for the same `role`.
+        # `bindings` with no members will result in an error.
+        # Corresponds to the JSON property `bindings`
+        # @return [Array<Google::Apis::GenomicsV1::Binding>]
+        attr_accessor :bindings
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @etag = args[:etag] if args.key?(:etag)
+          @version = args[:version] if args.key?(:version)
+          @bindings = args[:bindings] if args.key?(:bindings)
+        end
+      end
+      
+      # The read search request.
+      class SearchReadsRequest
+        include Google::Apis::Core::Hashable
+      
+        # The reference sequence name, for example `chr1`, `1`, or `chrX`. If set to
+        # `*`, only unmapped reads are returned. If unspecified, all reads (mapped
+        # and unmapped) are returned.
+        # Corresponds to the JSON property `referenceName`
+        # @return [String]
+        attr_accessor :reference_name
+      
+        # The IDs of the read groups sets within which to search for reads. All
+        # specified read group sets must be aligned against a common set of reference
+        # sequences; this defines the genomic coordinates for the query. Must specify
+        # one of `readGroupSetIds` or `readGroupIds`.
+        # Corresponds to the JSON property `readGroupSetIds`
+        # @return [Array<String>]
+        attr_accessor :read_group_set_ids
+      
+        # The IDs of the read groups within which to search for reads. All specified
+        # read groups must belong to the same read group sets. Must specify one of
+        # `readGroupSetIds` or `readGroupIds`.
+        # Corresponds to the JSON property `readGroupIds`
+        # @return [Array<String>]
+        attr_accessor :read_group_ids
+      
+        # The end position of the range on the reference, 0-based exclusive. If
+        # specified, `referenceName` must also be specified.
+        # Corresponds to the JSON property `end`
+        # @return [String]
+        attr_accessor :end
+      
+        # The continuation token, which is used to page through large result sets.
+        # To get the next page of results, set this parameter to the value of
+        # `nextPageToken` from the previous response.
+        # Corresponds to the JSON property `pageToken`
+        # @return [String]
+        attr_accessor :page_token
+      
+        # The maximum number of results to return in a single page. If unspecified,
+        # defaults to 256. The maximum value is 2048.
+        # Corresponds to the JSON property `pageSize`
+        # @return [Fixnum]
+        attr_accessor :page_size
+      
+        # The start position of the range on the reference, 0-based inclusive. If
+        # specified, `referenceName` must also be specified.
+        # Corresponds to the JSON property `start`
+        # @return [String]
+        attr_accessor :start
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @reference_name = args[:reference_name] if args.key?(:reference_name)
+          @read_group_set_ids = args[:read_group_set_ids] if args.key?(:read_group_set_ids)
+          @read_group_ids = args[:read_group_ids] if args.key?(:read_group_ids)
+          @end = args[:end] if args.key?(:end)
+          @page_token = args[:page_token] if args.key?(:page_token)
+          @page_size = args[:page_size] if args.key?(:page_size)
+          @start = args[:start] if args.key?(:start)
+        end
+      end
+      
+      # The request message for Operations.CancelOperation.
+      class CancelOperationRequest
+        include Google::Apis::Core::Hashable
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+        end
+      end
+      
+      # An annotation describes a region of reference genome. The value of an
+      # annotation may be one of several canonical types, supplemented by arbitrary
+      # info tags. An annotation is not inherently associated with a specific
+      # sample or individual (though a client could choose to use annotations in
+      # this way). Example canonical annotation types are `GENE` and
+      # `VARIANT`.
+      class Annotation
+        include Google::Apis::Core::Hashable
+      
+        # A transcript represents the assertion that a particular region of the
+        # reference genome may be transcribed as RNA.
+        # Corresponds to the JSON property `transcript`
+        # @return [Google::Apis::GenomicsV1::Transcript]
+        attr_accessor :transcript
+      
+        # The start position of the range on the reference, 0-based inclusive.
+        # Corresponds to the JSON property `start`
+        # @return [String]
+        attr_accessor :start
+      
+        # The annotation set to which this annotation belongs.
+        # Corresponds to the JSON property `annotationSetId`
+        # @return [String]
+        attr_accessor :annotation_set_id
+      
+        # The display name of this annotation.
+        # Corresponds to the JSON property `name`
+        # @return [String]
+        attr_accessor :name
+      
+        # A variant annotation, which describes the effect of a variant on the
+        # genome, the coding sequence, and/or higher level consequences at the
+        # organism level e.g. pathogenicity. This field is only set for annotations
+        # of type `VARIANT`.
+        # Corresponds to the JSON property `variant`
+        # @return [Google::Apis::GenomicsV1::VariantAnnotation]
+        attr_accessor :variant
+      
+        # The ID of the Google Genomics reference associated with this range.
+        # Corresponds to the JSON property `referenceId`
+        # @return [String]
+        attr_accessor :reference_id
+      
+        # The server-generated annotation ID, unique across all annotations.
+        # Corresponds to the JSON property `id`
+        # @return [String]
+        attr_accessor :id
+      
+        # Whether this range refers to the reverse strand, as opposed to the forward
+        # strand. Note that regardless of this field, the start/end position of the
+        # range always refer to the forward strand.
+        # Corresponds to the JSON property `reverseStrand`
+        # @return [Boolean]
+        attr_accessor :reverse_strand
+        alias_method :reverse_strand?, :reverse_strand
+      
+        # The display name corresponding to the reference specified by
+        # `referenceId`, for example `chr1`, `1`, or `chrX`.
+        # Corresponds to the JSON property `referenceName`
+        # @return [String]
+        attr_accessor :reference_name
+      
+        # The data type for this annotation. Must match the containing annotation
+        # set's type.
+        # Corresponds to the JSON property `type`
+        # @return [String]
+        attr_accessor :type
+      
+        # A map of additional read alignment information. This must be of the form
+        # map<string, string[]> (string key mapping to a list of string values).
+        # Corresponds to the JSON property `info`
+        # @return [Hash<String,Array<Object>>]
+        attr_accessor :info
+      
+        # The end position of the range on the reference, 0-based exclusive.
+        # Corresponds to the JSON property `end`
+        # @return [String]
+        attr_accessor :end
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @transcript = args[:transcript] if args.key?(:transcript)
+          @start = args[:start] if args.key?(:start)
+          @annotation_set_id = args[:annotation_set_id] if args.key?(:annotation_set_id)
+          @name = args[:name] if args.key?(:name)
+          @variant = args[:variant] if args.key?(:variant)
+          @reference_id = args[:reference_id] if args.key?(:reference_id)
+          @id = args[:id] if args.key?(:id)
+          @reverse_strand = args[:reverse_strand] if args.key?(:reverse_strand)
+          @reference_name = args[:reference_name] if args.key?(:reference_name)
+          @type = args[:type] if args.key?(:type)
+          @info = args[:info] if args.key?(:info)
+          @end = args[:end] if args.key?(:end)
+        end
+      end
+      
+      # This resource represents a long-running operation that is the result of a
+      # network API call.
+      class Operation
+        include Google::Apis::Core::Hashable
+      
+        # If importing ReadGroupSets, an ImportReadGroupSetsResponse is returned. If
+        # importing Variants, an ImportVariantsResponse is returned. For pipelines and
+        # exports, an empty response is returned.
+        # Corresponds to the JSON property `response`
+        # @return [Hash<String,Object>]
+        attr_accessor :response
+      
+        # The server-assigned name, which is only unique within the same service that
+        # originally returns it. For example&#58; `operations/CJHU7Oi_ChDrveSpBRjfuL-
+        # qzoWAgEw`
+        # Corresponds to the JSON property `name`
+        # @return [String]
+        attr_accessor :name
+      
+        # The `Status` type defines a logical error model that is suitable for different
+        # programming environments, including REST APIs and RPC APIs. It is used by
+        # [gRPC](https://github.com/grpc). The error model is designed to be:
+        # - Simple to use and understand for most users
+        # - Flexible enough to meet unexpected needs
+        # # Overview
+        # The `Status` message contains three pieces of data: error code, error message,
+        # and error details. The error code should be an enum value of
+        # google.rpc.Code, but it may accept additional error codes if needed.  The
+        # error message should be a developer-facing English message that helps
+        # developers *understand* and *resolve* the error. If a localized user-facing
+        # error message is needed, put the localized message in the error details or
+        # localize it in the client. The optional error details may contain arbitrary
+        # information about the error. There is a predefined set of error detail types
+        # in the package `google.rpc` which can be used for common error conditions.
+        # # Language mapping
+        # The `Status` message is the logical representation of the error model, but it
+        # is not necessarily the actual wire format. When the `Status` message is
+        # exposed in different client libraries and different wire protocols, it can be
+        # mapped differently. For example, it will likely be mapped to some exceptions
+        # in Java, but more likely mapped to some error codes in C.
+        # # Other uses
+        # The error model and the `Status` message can be used in a variety of
+        # environments, either with or without APIs, to provide a
+        # consistent developer experience across different environments.
+        # Example uses of this error model include:
+        # - Partial errors. If a service needs to return partial errors to the client,
+        # it may embed the `Status` in the normal response to indicate the partial
+        # errors.
+        # - Workflow errors. A typical workflow has multiple steps. Each step may
+        # have a `Status` message for error reporting purpose.
+        # - Batch operations. If a client uses batch request and batch response, the
+        # `Status` message should be used directly inside batch response, one for
+        # each error sub-response.
+        # - Asynchronous operations. If an API call embeds asynchronous operation
+        # results in its response, the status of those operations should be
+        # represented directly using the `Status` message.
+        # - Logging. If some API errors are stored in logs, the message `Status` could
+        # be used directly after any stripping needed for security/privacy reasons.
+        # Corresponds to the JSON property `error`
+        # @return [Google::Apis::GenomicsV1::Status]
+        attr_accessor :error
+      
+        # An OperationMetadata object. This will always be returned with the Operation.
+        # Corresponds to the JSON property `metadata`
+        # @return [Hash<String,Object>]
+        attr_accessor :metadata
+      
+        # If the value is `false`, it means the operation is still in progress.
+        # If true, the operation is completed, and either `error` or `response` is
+        # available.
+        # Corresponds to the JSON property `done`
+        # @return [Boolean]
+        attr_accessor :done
+        alias_method :done?, :done
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @response = args[:response] if args.key?(:response)
+          @name = args[:name] if args.key?(:name)
+          @error = args[:error] if args.key?(:error)
+          @metadata = args[:metadata] if args.key?(:metadata)
+          @done = args[:done] if args.key?(:done)
+        end
+      end
+      
+      # Runtime metadata that will be populated in the
+      # runtimeMetadata
+      # field of the Operation associated with a RunPipeline execution.
+      class RuntimeMetadata
+        include Google::Apis::Core::Hashable
+      
+        # Describes a Compute Engine resource that is being managed by a running
+        # pipeline.
+        # Corresponds to the JSON property `computeEngine`
+        # @return [Google::Apis::GenomicsV1::ComputeEngine]
+        attr_accessor :compute_engine
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @compute_engine = args[:compute_engine] if args.key?(:compute_engine)
+        end
+      end
+      
+      # The read group set import response.
+      class ImportReadGroupSetsResponse
+        include Google::Apis::Core::Hashable
+      
+        # IDs of the read group sets that were created.
+        # Corresponds to the JSON property `readGroupSetIds`
+        # @return [Array<String>]
+        attr_accessor :read_group_set_ids
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @read_group_set_ids = args[:read_group_set_ids] if args.key?(:read_group_set_ids)
+        end
+      end
+      
+      # A call represents the determination of genotype with respect to a particular
+      # variant. It may include associated information such as quality and phasing.
+      # For example, a call might assign a probability of 0.32 to the occurrence of
+      # a SNP named rs1234 in a call set with the name NA12345.
+      class VariantCall
+        include Google::Apis::Core::Hashable
+      
+        # If this field is present, this variant call's genotype ordering implies
+        # the phase of the bases and is consistent with any other variant calls in
+        # the same reference sequence which have the same phaseset value.
+        # When importing data from VCF, if the genotype data was phased but no
+        # phase set was specified this field will be set to `*`.
+        # Corresponds to the JSON property `phaseset`
+        # @return [String]
+        attr_accessor :phaseset
+      
+        # A map of additional variant call information. This must be of the form
+        # map<string, string[]> (string key mapping to a list of string values).
+        # Corresponds to the JSON property `info`
+        # @return [Hash<String,Array<Object>>]
+        attr_accessor :info
+      
+        # The name of the call set this variant call belongs to.
+        # Corresponds to the JSON property `callSetName`
+        # @return [String]
+        attr_accessor :call_set_name
+      
+        # The genotype likelihoods for this variant call. Each array entry
+        # represents how likely a specific genotype is for this call. The value
+        # ordering is defined by the GL tag in the VCF spec.
+        # If Phred-scaled genotype likelihood scores (PL) are available and
+        # log10(P) genotype likelihood scores (GL) are not, PL scores are converted
+        # to GL scores.  If both are available, PL scores are stored in `info`.
+        # Corresponds to the JSON property `genotypeLikelihood`
+        # @return [Array<Float>]
+        attr_accessor :genotype_likelihood
+      
+        # The ID of the call set this variant call belongs to.
+        # Corresponds to the JSON property `callSetId`
+        # @return [String]
+        attr_accessor :call_set_id
+      
+        # The genotype of this variant call. Each value represents either the value
+        # of the `referenceBases` field or a 1-based index into
+        # `alternateBases`. If a variant had a `referenceBases`
+        # value of `T` and an `alternateBases`
+        # value of `["A", "C"]`, and the `genotype` was
+        # `[2, 1]`, that would mean the call
+        # represented the heterozygous value `CA` for this variant.
+        # If the `genotype` was instead `[0, 1]`, the
+        # represented value would be `TA`. Ordering of the
+        # genotype values is important if the `phaseset` is present.
+        # If a genotype is not called (that is, a `.` is present in the
+        # GT string) -1 is returned.
+        # Corresponds to the JSON property `genotype`
+        # @return [Array<Fixnum>]
+        attr_accessor :genotype
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @phaseset = args[:phaseset] if args.key?(:phaseset)
+          @info = args[:info] if args.key?(:info)
+          @call_set_name = args[:call_set_name] if args.key?(:call_set_name)
+          @genotype_likelihood = args[:genotype_likelihood] if args.key?(:genotype_likelihood)
+          @call_set_id = args[:call_set_id] if args.key?(:call_set_id)
+          @genotype = args[:genotype] if args.key?(:genotype)
+        end
+      end
+      
+      # The variant search response.
+      class SearchVariantsResponse
+        include Google::Apis::Core::Hashable
+      
+        # The continuation token, which is used to page through large result sets.
+        # Provide this value in a subsequent request to return the next page of
+        # results. This field will be empty if there aren't any additional results.
+        # Corresponds to the JSON property `nextPageToken`
+        # @return [String]
+        attr_accessor :next_page_token
+      
+        # The list of matching Variants.
+        # Corresponds to the JSON property `variants`
+        # @return [Array<Google::Apis::GenomicsV1::Variant>]
+        attr_accessor :variants
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @next_page_token = args[:next_page_token] if args.key?(:next_page_token)
+          @variants = args[:variants] if args.key?(:variants)
+        end
+      end
+      
+      # 
+      class ListBasesResponse
+        include Google::Apis::Core::Hashable
+      
+        # A substring of the bases that make up this reference.
+        # Corresponds to the JSON property `sequence`
+        # @return [String]
+        attr_accessor :sequence
+      
+        # The offset position (0-based) of the given `sequence` from the
+        # start of this `Reference`. This value will differ for each page
+        # in a paginated request.
+        # Corresponds to the JSON property `offset`
+        # @return [String]
+        attr_accessor :offset
+      
+        # The continuation token, which is used to page through large result sets.
+        # Provide this value in a subsequent request to return the next page of
+        # results. This field will be empty if there aren't any additional results.
+        # Corresponds to the JSON property `nextPageToken`
+        # @return [String]
+        attr_accessor :next_page_token
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @sequence = args[:sequence] if args.key?(:sequence)
+          @offset = args[:offset] if args.key?(:offset)
+          @next_page_token = args[:next_page_token] if args.key?(:next_page_token)
+        end
+      end
+      
+      # The `Status` type defines a logical error model that is suitable for different
+      # programming environments, including REST APIs and RPC APIs. It is used by
+      # [gRPC](https://github.com/grpc). The error model is designed to be:
+      # - Simple to use and understand for most users
+      # - Flexible enough to meet unexpected needs
+      # # Overview
+      # The `Status` message contains three pieces of data: error code, error message,
+      # and error details. The error code should be an enum value of
+      # google.rpc.Code, but it may accept additional error codes if needed.  The
+      # error message should be a developer-facing English message that helps
+      # developers *understand* and *resolve* the error. If a localized user-facing
+      # error message is needed, put the localized message in the error details or
+      # localize it in the client. The optional error details may contain arbitrary
+      # information about the error. There is a predefined set of error detail types
+      # in the package `google.rpc` which can be used for common error conditions.
+      # # Language mapping
+      # The `Status` message is the logical representation of the error model, but it
+      # is not necessarily the actual wire format. When the `Status` message is
+      # exposed in different client libraries and different wire protocols, it can be
+      # mapped differently. For example, it will likely be mapped to some exceptions
+      # in Java, but more likely mapped to some error codes in C.
+      # # Other uses
+      # The error model and the `Status` message can be used in a variety of
+      # environments, either with or without APIs, to provide a
+      # consistent developer experience across different environments.
+      # Example uses of this error model include:
+      # - Partial errors. If a service needs to return partial errors to the client,
+      # it may embed the `Status` in the normal response to indicate the partial
+      # errors.
+      # - Workflow errors. A typical workflow has multiple steps. Each step may
+      # have a `Status` message for error reporting purpose.
+      # - Batch operations. If a client uses batch request and batch response, the
+      # `Status` message should be used directly inside batch response, one for
+      # each error sub-response.
+      # - Asynchronous operations. If an API call embeds asynchronous operation
+      # results in its response, the status of those operations should be
+      # represented directly using the `Status` message.
+      # - Logging. If some API errors are stored in logs, the message `Status` could
+      # be used directly after any stripping needed for security/privacy reasons.
+      class Status
+        include Google::Apis::Core::Hashable
+      
+        # A developer-facing error message, which should be in English. Any
+        # user-facing error message should be localized and sent in the
+        # google.rpc.Status.details field, or localized by the client.
+        # Corresponds to the JSON property `message`
+        # @return [String]
+        attr_accessor :message
+      
+        # A list of messages that carry the error details.  There will be a
+        # common set of message types for APIs to use.
+        # Corresponds to the JSON property `details`
+        # @return [Array<Hash<String,Object>>]
+        attr_accessor :details
+      
+        # The status code, which should be an enum value of google.rpc.Code.
+        # Corresponds to the JSON property `code`
+        # @return [Fixnum]
+        attr_accessor :code
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @message = args[:message] if args.key?(:message)
+          @details = args[:details] if args.key?(:details)
+          @code = args[:code] if args.key?(:code)
+        end
+      end
+      
+      # 
+      class UndeleteDatasetRequest
+        include Google::Apis::Core::Hashable
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+        end
+      end
+      
+      # Associates `members` with a `role`.
+      class Binding
+        include Google::Apis::Core::Hashable
+      
+        # Specifies the identities requesting access for a Cloud Platform resource.
+        # `members` can have the following values:
+        # * `allUsers`: A special identifier that represents anyone who is
+        # on the internet; with or without a Google account.
+        # * `allAuthenticatedUsers`: A special identifier that represents anyone
+        # who is authenticated with a Google account or a service account.
+        # * `user:`emailid``: An email address that represents a specific Google
+        # account. For example, `alice@gmail.com` or `joe@example.com`.
+        # * `serviceAccount:`emailid``: An email address that represents a service
+        # account. For example, `my-other-app@appspot.gserviceaccount.com`.
+        # * `group:`emailid``: An email address that represents a Google group.
+        # For example, `admins@example.com`.
+        # * `domain:`domain``: A Google Apps domain name that represents all the
+        # users of that domain. For example, `google.com` or `example.com`.
+        # Corresponds to the JSON property `members`
+        # @return [Array<String>]
+        attr_accessor :members
+      
+        # Role that is assigned to `members`.
+        # For example, `roles/viewer`, `roles/editor`, or `roles/owner`.
+        # Required
+        # Corresponds to the JSON property `role`
+        # @return [String]
+        attr_accessor :role
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @members = args[:members] if args.key?(:members)
+          @role = args[:role] if args.key?(:role)
+        end
+      end
+      
+      # A 0-based half-open genomic coordinate range for search requests.
+      class Range
+        include Google::Apis::Core::Hashable
+      
+        # The start position of the range on the reference, 0-based inclusive.
+        # Corresponds to the JSON property `start`
+        # @return [String]
+        attr_accessor :start
+      
+        # The end position of the range on the reference, 0-based exclusive.
+        # Corresponds to the JSON property `end`
+        # @return [String]
+        attr_accessor :end
+      
+        # The reference sequence name, for example `chr1`,
+        # `1`, or `chrX`.
+        # Corresponds to the JSON property `referenceName`
+        # @return [String]
+        attr_accessor :reference_name
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @start = args[:start] if args.key?(:start)
+          @end = args[:end] if args.key?(:end)
+          @reference_name = args[:reference_name] if args.key?(:reference_name)
+        end
+      end
+      
+      # A variant set is a collection of call sets and variants. It contains summary
+      # statistics of those contents. A variant set belongs to a dataset.
+      # For more genomics resource definitions, see [Fundamentals of Google
+      # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
+      class VariantSet
+        include Google::Apis::Core::Hashable
+      
+        # The metadata associated with this variant set.
+        # Corresponds to the JSON property `metadata`
+        # @return [Array<Google::Apis::GenomicsV1::VariantSetMetadata>]
+        attr_accessor :metadata
+      
+        # A list of all references used by the variants in a variant set
+        # with associated coordinate upper bounds for each one.
+        # Corresponds to the JSON property `referenceBounds`
+        # @return [Array<Google::Apis::GenomicsV1::ReferenceBound>]
+        attr_accessor :reference_bounds
+      
+        # The server-generated variant set ID, unique across all variant sets.
+        # Corresponds to the JSON property `id`
+        # @return [String]
+        attr_accessor :id
+      
+        # A textual description of this variant set.
+        # Corresponds to the JSON property `description`
+        # @return [String]
+        attr_accessor :description
+      
+        # The dataset to which this variant set belongs.
+        # Corresponds to the JSON property `datasetId`
+        # @return [String]
+        attr_accessor :dataset_id
+      
+        # User-specified, mutable name.
+        # Corresponds to the JSON property `name`
+        # @return [String]
+        attr_accessor :name
+      
+        # The reference set to which the variant set is mapped. The reference set
+        # describes the alignment provenance of the variant set, while the
+        # `referenceBounds` describe the shape of the actual variant data. The
+        # reference set's reference names are a superset of those found in the
+        # `referenceBounds`.
+        # For example, given a variant set that is mapped to the GRCh38 reference set
+        # and contains a single variant on reference 'X', `referenceBounds` would
+        # contain only an entry for 'X', while the associated reference set
+        # enumerates all possible references: '1', '2', 'X', 'Y', 'MT', etc.
+        # Corresponds to the JSON property `referenceSetId`
+        # @return [String]
+        attr_accessor :reference_set_id
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @metadata = args[:metadata] if args.key?(:metadata)
+          @reference_bounds = args[:reference_bounds] if args.key?(:reference_bounds)
+          @id = args[:id] if args.key?(:id)
+          @description = args[:description] if args.key?(:description)
+          @dataset_id = args[:dataset_id] if args.key?(:dataset_id)
+          @name = args[:name] if args.key?(:name)
+          @reference_set_id = args[:reference_set_id] if args.key?(:reference_set_id)
+        end
+      end
+      
+      # 
+      class BatchCreateAnnotationsResponse
+        include Google::Apis::Core::Hashable
+      
+        # The resulting per-annotation entries, ordered consistently with the
+        # original request.
+        # Corresponds to the JSON property `entries`
+        # @return [Array<Google::Apis::GenomicsV1::Entry>]
+        attr_accessor :entries
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @entries = args[:entries] if args.key?(:entries)
+        end
+      end
+      
+      # ReferenceBound records an upper bound for the starting coordinate of
+      # variants in a particular reference.
+      class ReferenceBound
+        include Google::Apis::Core::Hashable
+      
+        # An upper bound (inclusive) on the starting coordinate of any
+        # variant in the reference sequence.
+        # Corresponds to the JSON property `upperBound`
+        # @return [String]
+        attr_accessor :upper_bound
+      
+        # The name of the reference associated with this reference bound.
+        # Corresponds to the JSON property `referenceName`
+        # @return [String]
+        attr_accessor :reference_name
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @upper_bound = args[:upper_bound] if args.key?(:upper_bound)
+          @reference_name = args[:reference_name] if args.key?(:reference_name)
+        end
+      end
+      
+      # The call set search response.
+      class SearchCallSetsResponse
+        include Google::Apis::Core::Hashable
+      
+        # The continuation token, which is used to page through large result sets.
+        # Provide this value in a subsequent request to return the next page of
+        # results. This field will be empty if there aren't any additional results.
+        # Corresponds to the JSON property `nextPageToken`
+        # @return [String]
+        attr_accessor :next_page_token
+      
+        # The list of matching call sets.
+        # Corresponds to the JSON property `callSets`
+        # @return [Array<Google::Apis::GenomicsV1::CallSet>]
+        attr_accessor :call_sets
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @next_page_token = args[:next_page_token] if args.key?(:next_page_token)
+          @call_sets = args[:call_sets] if args.key?(:call_sets)
+        end
+      end
+      
+      # A variant represents a change in DNA sequence relative to a reference
+      # sequence. For example, a variant could represent a SNP or an insertion.
+      # Variants belong to a variant set.
+      # For more genomics resource definitions, see [Fundamentals of Google
+      # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
+      # Each of the calls on a variant represent a determination of genotype with
+      # respect to that variant. For example, a call might assign probability of 0.32
+      # to the occurrence of a SNP named rs1234 in a sample named NA12345. A call
+      # belongs to a call set, which contains related calls typically from one
+      # sample.
+      class Variant
+        include Google::Apis::Core::Hashable
+      
+        # A measure of how likely this variant is to be real.
+        # A higher value is better.
+        # Corresponds to the JSON property `quality`
+        # @return [Float]
+        attr_accessor :quality
+      
+        # The server-generated variant ID, unique across all variants.
+        # Corresponds to the JSON property `id`
+        # @return [String]
+        attr_accessor :id
+      
+        # The ID of the variant set this variant belongs to.
+        # Corresponds to the JSON property `variantSetId`
+        # @return [String]
+        attr_accessor :variant_set_id
+      
+        # The reference on which this variant occurs.
+        # (such as `chr20` or `X`)
+        # Corresponds to the JSON property `referenceName`
+        # @return [String]
+        attr_accessor :reference_name
+      
+        # A map of additional variant information. This must be of the form
+        # map<string, string[]> (string key mapping to a list of string values).
+        # Corresponds to the JSON property `info`
+        # @return [Hash<String,Array<Object>>]
+        attr_accessor :info
+      
+        # The reference bases for this variant. They start at the given
+        # position.
+        # Corresponds to the JSON property `referenceBases`
+        # @return [String]
+        attr_accessor :reference_bases
+      
+        # Names for the variant, for example a RefSNP ID.
+        # Corresponds to the JSON property `names`
+        # @return [Array<String>]
+        attr_accessor :names
+      
+        # The bases that appear instead of the reference bases.
+        # Corresponds to the JSON property `alternateBases`
+        # @return [Array<String>]
+        attr_accessor :alternate_bases
+      
+        # The end position (0-based) of this variant. This corresponds to the first
+        # base after the last base in the reference allele. So, the length of
+        # the reference allele is (end - start). This is useful for variants
+        # that don't explicitly give alternate bases, for example large deletions.
+        # Corresponds to the JSON property `end`
+        # @return [String]
+        attr_accessor :end
+      
+        # A list of filters (normally quality filters) this variant has failed.
+        # `PASS` indicates this variant has passed all filters.
+        # Corresponds to the JSON property `filter`
+        # @return [Array<String>]
+        attr_accessor :filter
+      
+        # The variant calls for this particular variant. Each one represents the
+        # determination of genotype with respect to this variant.
+        # Corresponds to the JSON property `calls`
+        # @return [Array<Google::Apis::GenomicsV1::VariantCall>]
+        attr_accessor :calls
+      
+        # The date this variant was created, in milliseconds from the epoch.
+        # Corresponds to the JSON property `created`
+        # @return [String]
+        attr_accessor :created
+      
+        # The position at which this variant occurs (0-based).
+        # This corresponds to the first base of the string of reference bases.
+        # Corresponds to the JSON property `start`
+        # @return [String]
+        attr_accessor :start
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @quality = args[:quality] if args.key?(:quality)
+          @id = args[:id] if args.key?(:id)
+          @variant_set_id = args[:variant_set_id] if args.key?(:variant_set_id)
+          @reference_name = args[:reference_name] if args.key?(:reference_name)
+          @info = args[:info] if args.key?(:info)
+          @reference_bases = args[:reference_bases] if args.key?(:reference_bases)
+          @names = args[:names] if args.key?(:names)
+          @alternate_bases = args[:alternate_bases] if args.key?(:alternate_bases)
+          @end = args[:end] if args.key?(:end)
+          @filter = args[:filter] if args.key?(:filter)
+          @calls = args[:calls] if args.key?(:calls)
+          @created = args[:created] if args.key?(:created)
+          @start = args[:start] if args.key?(:start)
+        end
+      end
+      
+      # The response message for Operations.ListOperations.
+      class ListOperationsResponse
+        include Google::Apis::Core::Hashable
+      
+        # The standard List next-page token.
+        # Corresponds to the JSON property `nextPageToken`
+        # @return [String]
+        attr_accessor :next_page_token
+      
+        # A list of operations that matches the specified filter in the request.
+        # Corresponds to the JSON property `operations`
+        # @return [Array<Google::Apis::GenomicsV1::Operation>]
+        attr_accessor :operations
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @next_page_token = args[:next_page_token] if args.key?(:next_page_token)
+          @operations = args[:operations] if args.key?(:operations)
+        end
+      end
+      
+      # Metadata describing an Operation.
+      class OperationMetadata
+        include Google::Apis::Core::Hashable
+      
+        # Optional event messages that were generated during the job's execution.
+        # This also contains any warnings that were generated during import
+        # or export.
+        # Corresponds to the JSON property `events`
+        # @return [Array<Google::Apis::GenomicsV1::OperationEvent>]
+        attr_accessor :events
+      
+        # The time at which the job stopped running.
+        # Corresponds to the JSON property `endTime`
+        # @return [String]
+        attr_accessor :end_time
+      
+        # The time at which the job began to run.
+        # Corresponds to the JSON property `startTime`
+        # @return [String]
+        attr_accessor :start_time
+      
+        # The original request that started the operation. Note that this will be in
+        # current version of the API. If the operation was started with v1beta2 API
+        # and a GetOperation is performed on v1 API, a v1 request will be returned.
+        # Corresponds to the JSON property `request`
+        # @return [Hash<String,Object>]
+        attr_accessor :request
+      
+        # Runtime metadata on this Operation.
+        # Corresponds to the JSON property `runtimeMetadata`
+        # @return [Hash<String,Object>]
+        attr_accessor :runtime_metadata
+      
+        # The time at which the job was submitted to the Genomics service.
+        # Corresponds to the JSON property `createTime`
+        # @return [String]
+        attr_accessor :create_time
+      
+        # Optionally provided by the caller when submitting the request that creates
+        # the operation.
+        # Corresponds to the JSON property `labels`
+        # @return [Hash<String,String>]
+        attr_accessor :labels
+      
+        # The Google Cloud Project in which the job is scoped.
+        # Corresponds to the JSON property `projectId`
+        # @return [String]
+        attr_accessor :project_id
+      
+        # This field is deprecated. Use `labels` instead. Optionally provided by the
+        # caller when submitting the request that creates the operation.
+        # Corresponds to the JSON property `clientId`
+        # @return [String]
+        attr_accessor :client_id
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @events = args[:events] if args.key?(:events)
+          @end_time = args[:end_time] if args.key?(:end_time)
+          @start_time = args[:start_time] if args.key?(:start_time)
+          @request = args[:request] if args.key?(:request)
+          @runtime_metadata = args[:runtime_metadata] if args.key?(:runtime_metadata)
+          @create_time = args[:create_time] if args.key?(:create_time)
+          @labels = args[:labels] if args.key?(:labels)
+          @project_id = args[:project_id] if args.key?(:project_id)
+          @client_id = args[:client_id] if args.key?(:client_id)
+        end
+      end
+      
+      # The variant search request.
+      class SearchVariantsRequest
+        include Google::Apis::Core::Hashable
+      
+        # The maximum number of variants to return in a single page. If unspecified,
+        # defaults to 5000. The maximum value is 10000.
+        # Corresponds to the JSON property `pageSize`
+        # @return [Fixnum]
+        attr_accessor :page_size
+      
+        # Only return variant calls which belong to call sets with these ids.
+        # Leaving this blank returns all variant calls. If a variant has no
+        # calls belonging to any of these call sets, it won't be returned at all.
+        # Corresponds to the JSON property `callSetIds`
+        # @return [Array<String>]
+        attr_accessor :call_set_ids
+      
+        # Only return variants which have exactly this name.
+        # Corresponds to the JSON property `variantName`
+        # @return [String]
+        attr_accessor :variant_name
+      
+        # The beginning of the window (0-based, inclusive) for which
+        # overlapping variants should be returned. If unspecified, defaults to 0.
+        # Corresponds to the JSON property `start`
+        # @return [String]
+        attr_accessor :start
+      
+        # Required. Only return variants in this reference sequence.
+        # Corresponds to the JSON property `referenceName`
+        # @return [String]
+        attr_accessor :reference_name
+      
+        # At most one variant set ID must be provided. Only variants from this
+        # variant set will be returned. If omitted, a call set id must be included in
+        # the request.
+        # Corresponds to the JSON property `variantSetIds`
+        # @return [Array<String>]
+        attr_accessor :variant_set_ids
+      
+        # The end of the window, 0-based exclusive. If unspecified or 0, defaults to
+        # the length of the reference.
+        # Corresponds to the JSON property `end`
+        # @return [String]
+        attr_accessor :end
+      
+        # The continuation token, which is used to page through large result sets.
+        # To get the next page of results, set this parameter to the value of
+        # `nextPageToken` from the previous response.
+        # Corresponds to the JSON property `pageToken`
+        # @return [String]
+        attr_accessor :page_token
+      
+        # The maximum number of calls to return in a single page. Note that this
+        # limit may be exceeded in the event that a matching variant contains more
+        # calls than the requested maximum. If unspecified, defaults to 5000. The
+        # maximum value is 10000.
+        # Corresponds to the JSON property `maxCalls`
+        # @return [Fixnum]
+        attr_accessor :max_calls
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @page_size = args[:page_size] if args.key?(:page_size)
+          @call_set_ids = args[:call_set_ids] if args.key?(:call_set_ids)
+          @variant_name = args[:variant_name] if args.key?(:variant_name)
+          @start = args[:start] if args.key?(:start)
+          @reference_name = args[:reference_name] if args.key?(:reference_name)
+          @variant_set_ids = args[:variant_set_ids] if args.key?(:variant_set_ids)
+          @end = args[:end] if args.key?(:end)
+          @page_token = args[:page_token] if args.key?(:page_token)
+          @max_calls = args[:max_calls] if args.key?(:max_calls)
+        end
+      end
+      
+      # The read group set search request.
+      class SearchReadGroupSetsRequest
+        include Google::Apis::Core::Hashable
+      
+        # Restricts this query to read group sets within the given datasets. At least
+        # one ID must be provided.
+        # Corresponds to the JSON property `datasetIds`
+        # @return [Array<String>]
+        attr_accessor :dataset_ids
+      
+        # Only return read group sets for which a substring of the name matches this
+        # string.
+        # Corresponds to the JSON property `name`
+        # @return [String]
+        attr_accessor :name
+      
+        # The continuation token, which is used to page through large result sets.
+        # To get the next page of results, set this parameter to the value of
+        # `nextPageToken` from the previous response.
+        # Corresponds to the JSON property `pageToken`
+        # @return [String]
+        attr_accessor :page_token
+      
+        # The maximum number of results to return in a single page. If unspecified,
+        # defaults to 256. The maximum value is 1024.
+        # Corresponds to the JSON property `pageSize`
+        # @return [Fixnum]
+        attr_accessor :page_size
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @dataset_ids = args[:dataset_ids] if args.key?(:dataset_ids)
+          @name = args[:name] if args.key?(:name)
+          @page_token = args[:page_token] if args.key?(:page_token)
+          @page_size = args[:page_size] if args.key?(:page_size)
+        end
+      end
+      
+      # 
+      class SearchAnnotationsResponse
+        include Google::Apis::Core::Hashable
+      
+        # The continuation token, which is used to page through large result sets.
+        # Provide this value in a subsequent request to return the next page of
+        # results. This field will be empty if there aren't any additional results.
+        # Corresponds to the JSON property `nextPageToken`
+        # @return [String]
+        attr_accessor :next_page_token
+      
+        # The matching annotations.
+        # Corresponds to the JSON property `annotations`
+        # @return [Array<Google::Apis::GenomicsV1::Annotation>]
+        attr_accessor :annotations
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @next_page_token = args[:next_page_token] if args.key?(:next_page_token)
+          @annotations = args[:annotations] if args.key?(:annotations)
+        end
+      end
+      
+      # 
+      class ClinicalCondition
+        include Google::Apis::Core::Hashable
+      
+        # The OMIM id for this condition.
+        # Search for these IDs at http://omim.org/
+        # Corresponds to the JSON property `omimId`
+        # @return [String]
+        attr_accessor :omim_id
+      
+        # The set of external IDs for this condition.
+        # Corresponds to the JSON property `externalIds`
+        # @return [Array<Google::Apis::GenomicsV1::ExternalId>]
+        attr_accessor :external_ids
+      
+        # The MedGen concept id associated with this gene.
+        # Search for these IDs at http://www.ncbi.nlm.nih.gov/medgen/
+        # Corresponds to the JSON property `conceptId`
+        # @return [String]
+        attr_accessor :concept_id
+      
+        # A set of names for the condition.
+        # Corresponds to the JSON property `names`
+        # @return [Array<String>]
+        attr_accessor :names
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @omim_id = args[:omim_id] if args.key?(:omim_id)
+          @external_ids = args[:external_ids] if args.key?(:external_ids)
+          @concept_id = args[:concept_id] if args.key?(:concept_id)
+          @names = args[:names] if args.key?(:names)
+        end
+      end
+      
+      # The read search response.
+      class SearchReadsResponse
+        include Google::Apis::Core::Hashable
+      
+        # The continuation token, which is used to page through large result sets.
+        # Provide this value in a subsequent request to return the next page of
+        # results. This field will be empty if there aren't any additional results.
+        # Corresponds to the JSON property `nextPageToken`
+        # @return [String]
+        attr_accessor :next_page_token
+      
+        # The list of matching alignments sorted by mapped genomic coordinate,
+        # if any, ascending in position within the same reference. Unmapped reads,
+        # which have no position, are returned contiguously and are sorted in
+        # ascending lexicographic order by fragment name.
+        # Corresponds to the JSON property `alignments`
+        # @return [Array<Google::Apis::GenomicsV1::Read>]
+        attr_accessor :alignments
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @next_page_token = args[:next_page_token] if args.key?(:next_page_token)
+          @alignments = args[:alignments] if args.key?(:alignments)
+        end
+      end
+      
+      # 
+      class Program
+        include Google::Apis::Core::Hashable
+      
+        # The display name of the program. This is typically the colloquial name of
+        # the tool used, for example 'bwa' or 'picard'.
+        # Corresponds to the JSON property `name`
+        # @return [String]
+        attr_accessor :name
+      
+        # The command line used to run this program.
+        # Corresponds to the JSON property `commandLine`
+        # @return [String]
+        attr_accessor :command_line
+      
+        # The ID of the program run before this one.
+        # Corresponds to the JSON property `prevProgramId`
+        # @return [String]
+        attr_accessor :prev_program_id
+      
+        # The user specified locally unique ID of the program. Used along with
+        # `prevProgramId` to define an ordering between programs.
+        # Corresponds to the JSON property `id`
+        # @return [String]
+        attr_accessor :id
+      
+        # The version of the program run.
+        # Corresponds to the JSON property `version`
+        # @return [String]
+        attr_accessor :version
+      
+        def initialize(**args)
+           update!(**args)
+        end
+      
+        # Update properties of this object
+        def update!(**args)
+          @name = args[:name] if args.key?(:name)
+          @command_line = args[:command_line] if args.key?(:command_line)
+          @prev_program_id = args[:prev_program_id] if args.key?(:prev_program_id)
+          @id = args[:id] if args.key?(:id)
+          @version = args[:version] if args.key?(:version)
+        end
+      end
+    end
+  end
+end