bioroebe 0.10.80

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Files changed (802) hide show
  1. checksums.yaml +7 -0
  2. data/LICENSE.md +428 -0
  3. data/README.md +9280 -0
  4. data/bin/advanced_dotplot +7 -0
  5. data/bin/align_open_reading_frames +12 -0
  6. data/bin/all_positions_of_this_nucleotide +7 -0
  7. data/bin/aminoacid_composition +7 -0
  8. data/bin/aminoacid_frequencies +12 -0
  9. data/bin/aminoacid_substitution +7 -0
  10. data/bin/automatically_rename_this_fasta_file +7 -0
  11. data/bin/base_composition +7 -0
  12. data/bin/batch_create_windows_executables +7 -0
  13. data/bin/biomart_console +11 -0
  14. data/bin/bioroebe +27 -0
  15. data/bin/bioroebe_controller +10 -0
  16. data/bin/bioshell +26 -0
  17. data/bin/blosum_2D_table +12 -0
  18. data/bin/calculate_n50_value +12 -0
  19. data/bin/chunked_display +12 -0
  20. data/bin/codon_frequency +9 -0
  21. data/bin/codon_to_aminoacid +30 -0
  22. data/bin/colourize_this_fasta_sequence +14 -0
  23. data/bin/compact_fasta_file +7 -0
  24. data/bin/complement +7 -0
  25. data/bin/complementary_dna_strand +12 -0
  26. data/bin/complementary_rna_strand +12 -0
  27. data/bin/compseq +7 -0
  28. data/bin/consensus_sequence +17 -0
  29. data/bin/count_AT +12 -0
  30. data/bin/count_GC +12 -0
  31. data/bin/create_random_aminoacids +7 -0
  32. data/bin/decode_this_aminoacid_sequence +20 -0
  33. data/bin/deduce_aminoacid_sequence +13 -0
  34. data/bin/deduce_most_likely_aminoacid_sequence +7 -0
  35. data/bin/display_aminoacid_table +12 -0
  36. data/bin/display_open_reading_frames +7 -0
  37. data/bin/dna_to_aminoacid_sequence +7 -0
  38. data/bin/dna_to_rna +7 -0
  39. data/bin/downcase_chunked_display +12 -0
  40. data/bin/download_this_pdb +7 -0
  41. data/bin/fasta_index +7 -0
  42. data/bin/fetch_data_from_uniprot +12 -0
  43. data/bin/filter_away_invalid_nucleotides +12 -0
  44. data/bin/find_substring +19 -0
  45. data/bin/genbank_to_fasta +7 -0
  46. data/bin/hamming_distance +12 -0
  47. data/bin/input_as_dna +12 -0
  48. data/bin/is_palindrome +13 -0
  49. data/bin/leading_five_prime +7 -0
  50. data/bin/levensthein +7 -0
  51. data/bin/longest_ORF +14 -0
  52. data/bin/longest_substring +12 -0
  53. data/bin/n_stop_codons_in_this_sequence +15 -0
  54. data/bin/open_reading_frames +14 -0
  55. data/bin/overwrite_fasta_header +7 -0
  56. data/bin/palindrome_2D_structure +7 -0
  57. data/bin/palindrome_generator +7 -0
  58. data/bin/parse_fasta +7 -0
  59. data/bin/partner_nucleotide +9 -0
  60. data/bin/possible_codons_for_this_aminoacid +12 -0
  61. data/bin/random_dna_sequence +12 -0
  62. data/bin/random_sequence +12 -0
  63. data/bin/raw_hamming_distance +12 -0
  64. data/bin/return_longest_substring_via_LCS_algorithm +7 -0
  65. data/bin/reverse_complement +7 -0
  66. data/bin/reverse_sequence +7 -0
  67. data/bin/ruler +12 -0
  68. data/bin/scan_this_input_for_startcodons +12 -0
  69. data/bin/short_aminoacid_letter_from_long_aminoacid_name +7 -0
  70. data/bin/show_atomic_composition +7 -0
  71. data/bin/show_codon_usage +12 -0
  72. data/bin/show_fasta_header +7 -0
  73. data/bin/show_nucleotide_sequence +7 -0
  74. data/bin/show_this_codon_table +7 -0
  75. data/bin/show_this_dna_sequence +7 -0
  76. data/bin/showorf +14 -0
  77. data/bin/simplify_fasta +7 -0
  78. data/bin/sort_aminoacid_based_on_its_hydrophobicity +7 -0
  79. data/bin/split_this_fasta_file_into_chromosomes +7 -0
  80. data/bin/strict_filter_away_invalid_aminoacids +7 -0
  81. data/bin/taxonomy +63 -0
  82. data/bin/three_to_one +7 -0
  83. data/bin/to_rna +7 -0
  84. data/bin/trailing_three_prime +7 -0
  85. data/bin/trypsin_digest +7 -0
  86. data/bin/upcase_this_aminoacid_sequence_and_remove_numbers +7 -0
  87. data/bioroebe.gemspec +97 -0
  88. data/doc/IUPAC_aminoacids_code.md +36 -0
  89. data/doc/IUPAC_nucleotide_code.md +19 -0
  90. data/doc/README.gen +9237 -0
  91. data/doc/blosum.md +5 -0
  92. data/doc/compatibility/BIO_PHP.md +37 -0
  93. data/doc/compatibility/README.md +3 -0
  94. data/doc/compatibility/emboss.md +56 -0
  95. data/doc/extensive_usage_example.md +35 -0
  96. data/doc/german_names_for_the_aminoacids.md +27 -0
  97. data/doc/instructions_for_the_taxonomy_subproject.md +504 -0
  98. data/doc/legacy_paths.md +9 -0
  99. data/doc/pdb_ATOM_entry.md +33 -0
  100. data/doc/quality_control/README.md +2 -0
  101. data/doc/quality_control/commandline_applications.md +13 -0
  102. data/doc/resources.md +23 -0
  103. data/doc/setup.rb +1655 -0
  104. data/doc/statistics/statistics.md +41 -0
  105. data/doc/todo/README.md +5 -0
  106. data/doc/todo/bioroebe_GUI_todo.md +15 -0
  107. data/doc/todo/bioroebe_todo.md +2823 -0
  108. data/doc/using_biomart.md +258 -0
  109. data/html/test.html +144 -0
  110. data/lib/bioroebe/aminoacids/aminoacid_substitution.rb +118 -0
  111. data/lib/bioroebe/aminoacids/aminoacids_mass_table.rb +118 -0
  112. data/lib/bioroebe/aminoacids/codon_percentage.rb +189 -0
  113. data/lib/bioroebe/aminoacids/colourize_hydrophilic_and_hydrophobic_aminoacids.rb +110 -0
  114. data/lib/bioroebe/aminoacids/create_random_aminoacids.rb +221 -0
  115. data/lib/bioroebe/aminoacids/deduce_aminoacid_sequence.rb +460 -0
  116. data/lib/bioroebe/aminoacids/display_aminoacid_table.rb +231 -0
  117. data/lib/bioroebe/aminoacids/show_hydrophobicity.rb +184 -0
  118. data/lib/bioroebe/annotations/README.md +2 -0
  119. data/lib/bioroebe/annotations/create_annotation_format.rb +208 -0
  120. data/lib/bioroebe/autoinclude.rb +7 -0
  121. data/lib/bioroebe/base/base.rb +35 -0
  122. data/lib/bioroebe/base/colours.rb +14 -0
  123. data/lib/bioroebe/base/colours_for_base/colours_for_base.rb +275 -0
  124. data/lib/bioroebe/base/commandline_application/README.md +7 -0
  125. data/lib/bioroebe/base/commandline_application/aminoacids.rb +33 -0
  126. data/lib/bioroebe/base/commandline_application/commandline_application.rb +37 -0
  127. data/lib/bioroebe/base/commandline_application/commandline_arguments.rb +144 -0
  128. data/lib/bioroebe/base/commandline_application/directory.rb +33 -0
  129. data/lib/bioroebe/base/commandline_application/extract.rb +22 -0
  130. data/lib/bioroebe/base/commandline_application/misc.rb +485 -0
  131. data/lib/bioroebe/base/commandline_application/opn.rb +47 -0
  132. data/lib/bioroebe/base/commandline_application/reset.rb +40 -0
  133. data/lib/bioroebe/base/commandline_application/warnings.rb +36 -0
  134. data/lib/bioroebe/base/commandline_application/write_what_into.rb +29 -0
  135. data/lib/bioroebe/base/initialize.rb +18 -0
  136. data/lib/bioroebe/base/misc.rb +94 -0
  137. data/lib/bioroebe/base/namespace.rb +16 -0
  138. data/lib/bioroebe/base/prototype/README.md +12 -0
  139. data/lib/bioroebe/base/prototype/e_and_ee.rb +24 -0
  140. data/lib/bioroebe/base/prototype/misc.rb +108 -0
  141. data/lib/bioroebe/base/prototype/mkdir.rb +20 -0
  142. data/lib/bioroebe/base/prototype/prototype.rb +21 -0
  143. data/lib/bioroebe/base/prototype/reset.rb +26 -0
  144. data/lib/bioroebe/base/reset.rb +11 -0
  145. data/lib/bioroebe/biomart/LICENSE.md +27 -0
  146. data/lib/bioroebe/biomart/attribute.rb +77 -0
  147. data/lib/bioroebe/biomart/biomart.rb +227 -0
  148. data/lib/bioroebe/biomart/database.rb +128 -0
  149. data/lib/bioroebe/biomart/dataset.rb +572 -0
  150. data/lib/bioroebe/biomart/filter.rb +97 -0
  151. data/lib/bioroebe/biomart/server.rb +152 -0
  152. data/lib/bioroebe/blosum/blosum.rb +88 -0
  153. data/lib/bioroebe/calculate/calculate_blosum_score.rb +145 -0
  154. data/lib/bioroebe/calculate/calculate_gc_content.rb +301 -0
  155. data/lib/bioroebe/calculate/calculate_levensthein_distance.rb +100 -0
  156. data/lib/bioroebe/calculate/calculate_melting_temperature.rb +398 -0
  157. data/lib/bioroebe/calculate/calculate_melting_temperature_for_more_than_thirteen_nucleotides.rb +304 -0
  158. data/lib/bioroebe/calculate/calculate_the_position_specific_scoring_matrix.rb +166 -0
  159. data/lib/bioroebe/cell/README.md +1 -0
  160. data/lib/bioroebe/cell/cell.rb +63 -0
  161. data/lib/bioroebe/cleave_and_digest/README.md +2 -0
  162. data/lib/bioroebe/cleave_and_digest/cleave.rb +80 -0
  163. data/lib/bioroebe/cleave_and_digest/digestion.rb +75 -0
  164. data/lib/bioroebe/cleave_and_digest/trypsin.rb +192 -0
  165. data/lib/bioroebe/codon_tables/README.md +9 -0
  166. data/lib/bioroebe/codon_tables/frequencies/287_Pseudomonas_aeruginosa.yml +101 -0
  167. data/lib/bioroebe/codon_tables/frequencies/3702_Arabidopsis_thaliana.yml +77 -0
  168. data/lib/bioroebe/codon_tables/frequencies/4932_Saccharomyces_cerevisiae.yml +103 -0
  169. data/lib/bioroebe/codon_tables/frequencies/7227_Drosophila_melanogaster.yml +71 -0
  170. data/lib/bioroebe/codon_tables/frequencies/83333_Escherichia_coli_K12.yml +103 -0
  171. data/lib/bioroebe/codon_tables/frequencies/9606_Homo_sapiens.yml +123 -0
  172. data/lib/bioroebe/codon_tables/frequencies/9685_Felis_catus.yml +78 -0
  173. data/lib/bioroebe/codon_tables/frequencies/README.md +10 -0
  174. data/lib/bioroebe/codon_tables/frequencies/parse_frequency_table.rb +337 -0
  175. data/lib/bioroebe/codons/README.md +28 -0
  176. data/lib/bioroebe/codons/codon_table.rb +416 -0
  177. data/lib/bioroebe/codons/codon_tables.rb +123 -0
  178. data/lib/bioroebe/codons/codons.rb +517 -0
  179. data/lib/bioroebe/codons/convert_this_codon_to_that_aminoacid.rb +102 -0
  180. data/lib/bioroebe/codons/detect_minimal_codon.rb +180 -0
  181. data/lib/bioroebe/codons/determine_optimal_codons.rb +74 -0
  182. data/lib/bioroebe/codons/possible_codons_for_this_aminoacid.rb +380 -0
  183. data/lib/bioroebe/codons/sanitize_codon_frequency.rb +144 -0
  184. data/lib/bioroebe/codons/show_codon_tables.rb +130 -0
  185. data/lib/bioroebe/codons/show_codon_usage.rb +197 -0
  186. data/lib/bioroebe/codons/show_this_codon_table.rb +573 -0
  187. data/lib/bioroebe/codons/start_codons.rb +105 -0
  188. data/lib/bioroebe/colours/colour_schemes/README.md +10 -0
  189. data/lib/bioroebe/colours/colour_schemes/array_available_colour_schemes.rb +38 -0
  190. data/lib/bioroebe/colours/colour_schemes/buried.rb +70 -0
  191. data/lib/bioroebe/colours/colour_schemes/colour_scheme.rb +101 -0
  192. data/lib/bioroebe/colours/colour_schemes/colour_scheme_demo.rb +262 -0
  193. data/lib/bioroebe/colours/colour_schemes/helix.rb +65 -0
  194. data/lib/bioroebe/colours/colour_schemes/hydropathy.rb +70 -0
  195. data/lib/bioroebe/colours/colour_schemes/nucleotide.rb +47 -0
  196. data/lib/bioroebe/colours/colour_schemes/score.rb +112 -0
  197. data/lib/bioroebe/colours/colour_schemes/simple.rb +42 -0
  198. data/lib/bioroebe/colours/colour_schemes/strand.rb +65 -0
  199. data/lib/bioroebe/colours/colour_schemes/taylor.rb +58 -0
  200. data/lib/bioroebe/colours/colour_schemes/turn.rb +65 -0
  201. data/lib/bioroebe/colours/colour_schemes/zappo.rb +59 -0
  202. data/lib/bioroebe/colours/colourize_sequence.rb +262 -0
  203. data/lib/bioroebe/colours/colours.rb +119 -0
  204. data/lib/bioroebe/colours/misc_colours.rb +80 -0
  205. data/lib/bioroebe/colours/rev.rb +41 -0
  206. data/lib/bioroebe/colours/sdir.rb +21 -0
  207. data/lib/bioroebe/colours/sfancy.rb +21 -0
  208. data/lib/bioroebe/colours/sfile.rb +21 -0
  209. data/lib/bioroebe/colours/simp.rb +21 -0
  210. data/lib/bioroebe/colours/swarn.rb +29 -0
  211. data/lib/bioroebe/colours/use_colours.rb +27 -0
  212. data/lib/bioroebe/configuration/configuration.rb +114 -0
  213. data/lib/bioroebe/configuration/constants.rb +35 -0
  214. data/lib/bioroebe/constants/GUIs.rb +79 -0
  215. data/lib/bioroebe/constants/aminoacids_and_proteins.rb +146 -0
  216. data/lib/bioroebe/constants/base_directory.rb +120 -0
  217. data/lib/bioroebe/constants/carriage_return.rb +14 -0
  218. data/lib/bioroebe/constants/codon_tables.rb +77 -0
  219. data/lib/bioroebe/constants/database_constants.rb +107 -0
  220. data/lib/bioroebe/constants/files_and_directories.rb +579 -0
  221. data/lib/bioroebe/constants/misc.rb +189 -0
  222. data/lib/bioroebe/constants/newline.rb +14 -0
  223. data/lib/bioroebe/constants/nucleotides.rb +114 -0
  224. data/lib/bioroebe/constants/regex.rb +28 -0
  225. data/lib/bioroebe/constants/roebe.rb +38 -0
  226. data/lib/bioroebe/constants/row_terminator.rb +16 -0
  227. data/lib/bioroebe/constants/tabulator.rb +14 -0
  228. data/lib/bioroebe/constants/unicode.rb +12 -0
  229. data/lib/bioroebe/constants/urls.rb +50 -0
  230. data/lib/bioroebe/conversions/README.md +3 -0
  231. data/lib/bioroebe/conversions/convert_aminoacid_to_dna.rb +298 -0
  232. data/lib/bioroebe/conversions/dna_to_aminoacid_sequence.rb +569 -0
  233. data/lib/bioroebe/count/README.md +1 -0
  234. data/lib/bioroebe/count/count_amount_of_aminoacids.rb +352 -0
  235. data/lib/bioroebe/count/count_amount_of_nucleotides.rb +491 -0
  236. data/lib/bioroebe/count/count_at.rb +39 -0
  237. data/lib/bioroebe/count/count_gc.rb +43 -0
  238. data/lib/bioroebe/css/README.md +5 -0
  239. data/lib/bioroebe/css/project.css +121 -0
  240. data/lib/bioroebe/data/README.md +10 -0
  241. data/lib/bioroebe/data/bam/README.md +1 -0
  242. data/lib/bioroebe/data/data.txt +192 -0
  243. data/lib/bioroebe/data/fasta/GFP_mutant_3_coding_sequence.fasta +12 -0
  244. data/lib/bioroebe/data/fasta/alu_elements.fasta +42 -0
  245. data/lib/bioroebe/data/fasta/lady_slippers_orchid.fasta +1197 -0
  246. data/lib/bioroebe/data/fasta/loxP.fasta +2 -0
  247. data/lib/bioroebe/data/fasta/ls_orchid.fasta +1197 -0
  248. data/lib/bioroebe/data/fasta/pax6_in_mouse.fasta +1 -0
  249. data/lib/bioroebe/data/fasta/test.fasta +7 -0
  250. data/lib/bioroebe/data/fasta/test_DNA.fasta +1 -0
  251. data/lib/bioroebe/data/fastq/fastq_example_file.fastq +32 -0
  252. data/lib/bioroebe/data/fastq/fastq_example_file_SP1.fastq +1000 -0
  253. data/lib/bioroebe/data/fastq/one_random_fastq_entry.fastq +4 -0
  254. data/lib/bioroebe/data/genbank/sample_file.genbank +15 -0
  255. data/lib/bioroebe/data/genbank/standard.fasta +3 -0
  256. data/lib/bioroebe/data/gff/Escherichia_coli_K12_plasmid_F_DNA_NC_002483.1.gff3 +345 -0
  257. data/lib/bioroebe/data/gff/sample.gff +2 -0
  258. data/lib/bioroebe/data/gff/test_gene.gff +4 -0
  259. data/lib/bioroebe/data/gff/transcripts.gff +16 -0
  260. data/lib/bioroebe/data/gtf/README.md +1 -0
  261. data/lib/bioroebe/data/json/example_config.json +48 -0
  262. data/lib/bioroebe/data/pdb/1VII.pdb +754 -0
  263. data/lib/bioroebe/data/pdb/ala_phe_ala.pdb +228 -0
  264. data/lib/bioroebe/data/pdb/rcsb_pdb_1VII.fasta +2 -0
  265. data/lib/bioroebe/data/phylip/README.md +11 -0
  266. data/lib/bioroebe/data/phylip/example.phylip +7 -0
  267. data/lib/bioroebe/data/svg/example.svg +301 -0
  268. data/lib/bioroebe/databases/README.md +1 -0
  269. data/lib/bioroebe/databases/download_taxonomy_database.rb +102 -0
  270. data/lib/bioroebe/dotplots/README.md +5 -0
  271. data/lib/bioroebe/dotplots/advanced_dotplot.rb +256 -0
  272. data/lib/bioroebe/dotplots/dotplot.rb +184 -0
  273. data/lib/bioroebe/electron_microscopy/coordinate_analyzer.rb +191 -0
  274. data/lib/bioroebe/electron_microscopy/fix_pos_file.rb +102 -0
  275. data/lib/bioroebe/electron_microscopy/generate_em2em_file.rb +122 -0
  276. data/lib/bioroebe/electron_microscopy/parse_coordinates.rb +197 -0
  277. data/lib/bioroebe/electron_microscopy/read_file_xmd.rb +282 -0
  278. data/lib/bioroebe/electron_microscopy/simple_star_file_generator.rb +131 -0
  279. data/lib/bioroebe/encoding/README.md +2 -0
  280. data/lib/bioroebe/encoding/encoding.rb +45 -0
  281. data/lib/bioroebe/enzymes/README.md +2 -0
  282. data/lib/bioroebe/enzymes/has_this_restriction_enzyme.rb +46 -0
  283. data/lib/bioroebe/enzymes/restriction_enzyme.rb +200 -0
  284. data/lib/bioroebe/enzymes/restriction_enzymes_file.rb +72 -0
  285. data/lib/bioroebe/enzymes/return_restriction_enzyme_sequence_and_cut_position.rb +80 -0
  286. data/lib/bioroebe/enzymes/return_sequence_that_is_cut_via_restriction_enzyme.rb +65 -0
  287. data/lib/bioroebe/enzymes/show_restriction_enzymes.rb +119 -0
  288. data/lib/bioroebe/exceptions/README.md +2 -0
  289. data/lib/bioroebe/exceptions/exceptions.rb +17 -0
  290. data/lib/bioroebe/ext/LICENCE.md +5 -0
  291. data/lib/bioroebe/ext/README.md +7 -0
  292. data/lib/bioroebe/ext/main.cpp +45 -0
  293. data/lib/bioroebe/ext/nucleotide.cpp +24 -0
  294. data/lib/bioroebe/ext/nussinov_algorithm.cpp +348 -0
  295. data/lib/bioroebe/ext/sequence +0 -0
  296. data/lib/bioroebe/ext/sequence.cpp +162 -0
  297. data/lib/bioroebe/fasta_and_fastq/README.md +6 -0
  298. data/lib/bioroebe/fasta_and_fastq/autocorrect_the_name_of_this_fasta_file.rb +88 -0
  299. data/lib/bioroebe/fasta_and_fastq/compact_fasta_file/compact_fasta_file.rb +151 -0
  300. data/lib/bioroebe/fasta_and_fastq/display_how_many_fasta_entries_are_in_this_directory.rb +111 -0
  301. data/lib/bioroebe/fasta_and_fastq/download_fasta.rb +248 -0
  302. data/lib/bioroebe/fasta_and_fastq/fasta_defline/README.md +2 -0
  303. data/lib/bioroebe/fasta_and_fastq/fasta_defline/fasta_defline.rb +113 -0
  304. data/lib/bioroebe/fasta_and_fastq/fasta_parser.rb +167 -0
  305. data/lib/bioroebe/fasta_and_fastq/fastq_format_explainer.rb +131 -0
  306. data/lib/bioroebe/fasta_and_fastq/length_modifier/length_modifier.rb +87 -0
  307. data/lib/bioroebe/fasta_and_fastq/parse_fasta/constants.rb +50 -0
  308. data/lib/bioroebe/fasta_and_fastq/parse_fasta/initialize.rb +86 -0
  309. data/lib/bioroebe/fasta_and_fastq/parse_fasta/menu.rb +117 -0
  310. data/lib/bioroebe/fasta_and_fastq/parse_fasta/misc.rb +981 -0
  311. data/lib/bioroebe/fasta_and_fastq/parse_fasta/parse_fasta.rb +27 -0
  312. data/lib/bioroebe/fasta_and_fastq/parse_fasta/report.rb +156 -0
  313. data/lib/bioroebe/fasta_and_fastq/parse_fasta/reset.rb +128 -0
  314. data/lib/bioroebe/fasta_and_fastq/parse_fasta/run.rb +20 -0
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  577. data/lib/bioroebe/svg/track.rb +263 -0
  578. data/lib/bioroebe/taxonomy/README.md +1 -0
  579. data/lib/bioroebe/taxonomy/chart.rb +95 -0
  580. data/lib/bioroebe/taxonomy/class_methods.rb +181 -0
  581. data/lib/bioroebe/taxonomy/colours.rb +26 -0
  582. data/lib/bioroebe/taxonomy/constants.rb +218 -0
  583. data/lib/bioroebe/taxonomy/edit.rb +97 -0
  584. data/lib/bioroebe/taxonomy/help/help.rb +65 -0
  585. data/lib/bioroebe/taxonomy/help/helpline.rb +53 -0
  586. data/lib/bioroebe/taxonomy/info/check_available.rb +143 -0
  587. data/lib/bioroebe/taxonomy/info/info.rb +337 -0
  588. data/lib/bioroebe/taxonomy/info/is_dna.rb +150 -0
  589. data/lib/bioroebe/taxonomy/interactive.rb +1933 -0
  590. data/lib/bioroebe/taxonomy/menu.rb +905 -0
  591. data/lib/bioroebe/taxonomy/node.rb +118 -0
  592. data/lib/bioroebe/taxonomy/parse_fasta.rb +383 -0
  593. data/lib/bioroebe/taxonomy/shared.rb +287 -0
  594. data/lib/bioroebe/taxonomy/taxonomy.rb +521 -0
  595. data/lib/bioroebe/toplevel_methods/ad_hoc_task.rb +56 -0
  596. data/lib/bioroebe/toplevel_methods/aminoacids_and_proteins.rb +715 -0
  597. data/lib/bioroebe/toplevel_methods/atomic_composition.rb +198 -0
  598. data/lib/bioroebe/toplevel_methods/base_composition.rb +121 -0
  599. data/lib/bioroebe/toplevel_methods/blast.rb +153 -0
  600. data/lib/bioroebe/toplevel_methods/calculate_n50_value.rb +57 -0
  601. data/lib/bioroebe/toplevel_methods/cat.rb +71 -0
  602. data/lib/bioroebe/toplevel_methods/chunked_display.rb +92 -0
  603. data/lib/bioroebe/toplevel_methods/cliner.rb +81 -0
  604. data/lib/bioroebe/toplevel_methods/complement.rb +58 -0
  605. data/lib/bioroebe/toplevel_methods/convert_global_env.rb +39 -0
  606. data/lib/bioroebe/toplevel_methods/databases.rb +73 -0
  607. data/lib/bioroebe/toplevel_methods/delimiter.rb +19 -0
  608. data/lib/bioroebe/toplevel_methods/digest.rb +71 -0
  609. data/lib/bioroebe/toplevel_methods/download_and_fetch_data.rb +146 -0
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  615. data/lib/bioroebe/toplevel_methods/fasta_and_fastq.rb +353 -0
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  617. data/lib/bioroebe/toplevel_methods/frequencies.rb +92 -0
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  621. data/lib/bioroebe/toplevel_methods/leading_five_prime_and_trailing_three_prime.rb +101 -0
  622. data/lib/bioroebe/toplevel_methods/levensthein.rb +63 -0
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  624. data/lib/bioroebe/toplevel_methods/longest_common_substring.rb +55 -0
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  628. data/lib/bioroebe/toplevel_methods/nucleotides.rb +715 -0
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  633. data/lib/bioroebe/toplevel_methods/palindromes.rb +127 -0
  634. data/lib/bioroebe/toplevel_methods/parse.rb +59 -0
  635. data/lib/bioroebe/toplevel_methods/phred_error_probability.rb +68 -0
  636. data/lib/bioroebe/toplevel_methods/rds.rb +24 -0
  637. data/lib/bioroebe/toplevel_methods/remove.rb +86 -0
  638. data/lib/bioroebe/toplevel_methods/return_source_code_of_this_method.rb +35 -0
  639. data/lib/bioroebe/toplevel_methods/return_subsequence_based_on_indices.rb +68 -0
  640. data/lib/bioroebe/toplevel_methods/rna_splicing.rb +73 -0
  641. data/lib/bioroebe/toplevel_methods/rnalfold.rb +69 -0
  642. data/lib/bioroebe/toplevel_methods/searching_and_finding.rb +116 -0
  643. data/lib/bioroebe/toplevel_methods/shuffleseq.rb +37 -0
  644. data/lib/bioroebe/toplevel_methods/statistics.rb +53 -0
  645. data/lib/bioroebe/toplevel_methods/sum_of_odd_integers.rb +62 -0
  646. data/lib/bioroebe/toplevel_methods/taxonomy.rb +187 -0
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  650. data/lib/bioroebe/toplevel_methods/truncate.rb +48 -0
  651. data/lib/bioroebe/toplevel_methods/url.rb +36 -0
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  654. data/lib/bioroebe/utility_scripts/analyse_local_dataset.rb +119 -0
  655. data/lib/bioroebe/utility_scripts/check_for_mismatches/check_for_mismatches.rb +230 -0
  656. data/lib/bioroebe/utility_scripts/compacter.rb +131 -0
  657. data/lib/bioroebe/utility_scripts/compseq/compseq.rb +529 -0
  658. data/lib/bioroebe/utility_scripts/consensus_sequence.rb +374 -0
  659. data/lib/bioroebe/utility_scripts/create_batch_entrez_file.rb +130 -0
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  661. data/lib/bioroebe/utility_scripts/determine_missing_nucleotides_percentage.rb +137 -0
  662. data/lib/bioroebe/utility_scripts/display_open_reading_frames/determine.rb +73 -0
  663. data/lib/bioroebe/utility_scripts/display_open_reading_frames/display_open_reading_frames.rb +31 -0
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  670. data/lib/bioroebe/utility_scripts/download_files_from_rebase.rb +72 -0
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  673. data/lib/bioroebe/utility_scripts/move_file_to_its_correct_location.rb +151 -0
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  675. data/lib/bioroebe/utility_scripts/pathways.rb +152 -0
  676. data/lib/bioroebe/utility_scripts/permutations.rb +145 -0
  677. data/lib/bioroebe/utility_scripts/punnet/punnet.rb +126 -0
  678. data/lib/bioroebe/utility_scripts/show_this_dna_sequence.rb +148 -0
  679. data/lib/bioroebe/utility_scripts/showorf/constants.rb +36 -0
  680. data/lib/bioroebe/utility_scripts/showorf/help.rb +33 -0
  681. data/lib/bioroebe/utility_scripts/showorf/initialize.rb +52 -0
  682. data/lib/bioroebe/utility_scripts/showorf/menu.rb +68 -0
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  684. data/lib/bioroebe/utility_scripts/showorf/run.rb +152 -0
  685. data/lib/bioroebe/utility_scripts/showorf/show.rb +97 -0
  686. data/lib/bioroebe/utility_scripts/showorf/showorf.rb +488 -0
  687. data/lib/bioroebe/version/version.rb +44 -0
  688. data/lib/bioroebe/viennarna/README.md +3 -0
  689. data/lib/bioroebe/viennarna/rnafold_wrapper.rb +196 -0
  690. data/lib/bioroebe/with_gui.rb +18 -0
  691. data/lib/bioroebe/www/bioroebe.cgi +44 -0
  692. data/lib/bioroebe/www/embeddable_interface.rb +686 -0
  693. data/lib/bioroebe/www/sinatra/sinatra.rb +1013 -0
  694. data/lib/bioroebe/yaml/agarose/agarose_concentrations.yml +21 -0
  695. data/lib/bioroebe/yaml/aminoacids/amino_acids.yml +92 -0
  696. data/lib/bioroebe/yaml/aminoacids/amino_acids_abbreviations.yml +31 -0
  697. data/lib/bioroebe/yaml/aminoacids/amino_acids_average_mass_table.yml +33 -0
  698. data/lib/bioroebe/yaml/aminoacids/amino_acids_classification.yml +18 -0
  699. data/lib/bioroebe/yaml/aminoacids/amino_acids_english.yml +26 -0
  700. data/lib/bioroebe/yaml/aminoacids/amino_acids_frequency.yml +44 -0
  701. data/lib/bioroebe/yaml/aminoacids/amino_acids_long_name_to_one_letter.yml +61 -0
  702. data/lib/bioroebe/yaml/aminoacids/amino_acids_molecular_formula.yml +32 -0
  703. data/lib/bioroebe/yaml/aminoacids/amino_acids_monoisotopic_mass_table.yml +38 -0
  704. data/lib/bioroebe/yaml/aminoacids/amino_acids_reste.yml +35 -0
  705. data/lib/bioroebe/yaml/aminoacids/amino_acids_three_to_one.yml +34 -0
  706. data/lib/bioroebe/yaml/aminoacids/hydropathy_table.yml +44 -0
  707. data/lib/bioroebe/yaml/aminoacids/molecular_weight.yml +29 -0
  708. data/lib/bioroebe/yaml/aminoacids/simple_aminoacids.yml +66 -0
  709. data/lib/bioroebe/yaml/aminoacids/weight_of_common_proteins.yml +33 -0
  710. data/lib/bioroebe/yaml/antisense/antisense.yml +9 -0
  711. data/lib/bioroebe/yaml/base_composition_of_dna.yml +37 -0
  712. data/lib/bioroebe/yaml/blosum/blosum45.yml +36 -0
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  717. data/lib/bioroebe/yaml/blosum/blosum_matrix.yml +200 -0
  718. data/lib/bioroebe/yaml/chromosomes/chromosome_numbers.yml +30 -0
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  750. data/lib/bioroebe/yaml/configuration/temp_dir.yml +1 -0
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  753. data/lib/bioroebe/yaml/configuration/use_this_database.yml +1 -0
  754. data/lib/bioroebe/yaml/create_these_directories_on_startup/create_these_directories_on_startup.yml +9 -0
  755. data/lib/bioroebe/yaml/default_dna_input.yml +3 -0
  756. data/lib/bioroebe/yaml/enzymes/enzyme_classes.yml +15 -0
  757. data/lib/bioroebe/yaml/enzymes/pH-Optima.yml +11 -0
  758. data/lib/bioroebe/yaml/fasta_and_fastq/fastq_quality_schemes.yml +44 -0
  759. data/lib/bioroebe/yaml/genomes/README.md +16 -0
  760. data/lib/bioroebe/yaml/humans/README.md +2 -0
  761. data/lib/bioroebe/yaml/humans/human_chromosomes.yml +53 -0
  762. data/lib/bioroebe/yaml/laboratory/README.md +1 -0
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  765. data/lib/bioroebe/yaml/nuclear_localization_sequences.yml +15 -0
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  767. data/lib/bioroebe/yaml/nucleotides/nucleotide_density.yml +10 -0
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  785. data/lib/bioroebe/yaml/sequences/README.md +2 -0
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  790. data/spec/testing_toplevel_method_editor.rb +20 -0
  791. data/spec/testing_toplevel_method_url.rb +15 -0
  792. data/spec/testing_toplevel_method_verbose.rb +13 -0
  793. data/test/advanced_svg_example.rb +307 -0
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  795. data/test/testing_codons.rb +45 -0
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  800. data/test/testing_svg_component_of_bioroebe_from_json_dataset.rb +34 -0
  801. data/test/testing_taxonomy.rb +22 -0
  802. metadata +1059 -0
@@ -0,0 +1,519 @@
1
+ #!/usr/bin/ruby -w
2
+ # Encoding: UTF-8
3
+ # frozen_string_literal: true
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+ # =========================================================================== #
5
+ # === Bioroebe::Gui::AntiSenseStrand
6
+ #
7
+ # This widget contains two entries (user input fields). These two entries
8
+ # correspond to sense and anti-sense in a DNA strand.
9
+ #
10
+ # In the first entry the user may only enter "atcg". These will be
11
+ # UPCASED automatically, so the real input will be "ATCG",
12
+ # respectively.
13
+ #
14
+ # Usage example:
15
+ #
16
+ # Bioroebe::GUI::AntiSenseStrand.new(ARGV)
17
+ #
18
+ # =========================================================================== #
19
+ # require 'bioroebe/gui/unified_widgets/anti_sense_strand/anti_sense_strand.rb'
20
+ # Bioroebe::GUI::AntiSenseStrand.new(ARGV)
21
+ # =========================================================================== #
22
+ module Bioroebe
23
+
24
+ module GUI
25
+
26
+ class AntiSenseStrand # === Bioroebe::GUI::AntiSenseStrand
27
+
28
+ begin
29
+ require 'simple_widgets'
30
+ include SimpleWidgets
31
+ extend SimpleWidgets
32
+ rescue LoadError; end
33
+
34
+ require 'bioroebe/constants/GUIs.rb'
35
+ include Bioroebe::GUI
36
+
37
+ # ========================================================================= #
38
+ # Toggle the GUI in use here after setting a default:
39
+ # ========================================================================= #
40
+ # use :gtk3
41
+ use :libui
42
+
43
+ # ========================================================================= #
44
+ # === NAMESPACE
45
+ # ========================================================================= #
46
+ NAMESPACE = inspect
47
+
48
+ # ========================================================================= #
49
+ # === TITLE
50
+ # ========================================================================= #
51
+ TITLE = 'Sense / Anti-Sense Strand'
52
+
53
+ # ========================================================================= #
54
+ # === WIDTH
55
+ # ========================================================================= #
56
+ WIDTH = 840
57
+
58
+ # ========================================================================= #
59
+ # === HEIGHT
60
+ # ========================================================================= #
61
+ HEIGHT = 400
62
+
63
+ # ========================================================================= #
64
+ # === MAX_LENGTH
65
+ # ========================================================================= #
66
+ MAX_LENGTH = 50_000
67
+
68
+ # ========================================================================= #
69
+ # === IMG_DNA_HELIX
70
+ # ========================================================================= #
71
+ IMG_DNA_HELIX =
72
+ '/home/x/data/images/science/biology/DNA_HELIX.jpg'
73
+
74
+ # ========================================================================= #
75
+ # === USE_THIS_FONT
76
+ # ========================================================================= #
77
+ USE_THIS_FONT = 'Hack 20'
78
+
79
+ # ========================================================================= #
80
+ # === initialize
81
+ # ========================================================================= #
82
+ def initialize(
83
+ commandline_arguments = ARGV,
84
+ run_already = true,
85
+ &block
86
+ )
87
+ parse_this_input_for_proper_widget_support(
88
+ commandline_arguments
89
+ )
90
+ register_sigint
91
+ reset
92
+ @use_this_as_the_options_hash = {
93
+ margin: true
94
+ }
95
+ # ======================================================================= #
96
+ # === Handle blocks next
97
+ # ======================================================================= #
98
+ if block_given?
99
+ yielded = yield
100
+ elsif use_gtk3?
101
+ yielded = :use_vbox_on_the_toplevel
102
+ else
103
+ yielded = nil
104
+ end
105
+ case yielded
106
+ # ===================================================================== #
107
+ # === :use_vbox_on_the_toplevel
108
+ # ===================================================================== #
109
+ when :use_vbox_on_the_toplevel
110
+ @use_this_as_the_options_hash.update(
111
+ use_vbox_on_the_toplevel: true
112
+ )
113
+ end
114
+ run if run_already
115
+ end
116
+
117
+ # ========================================================================= #
118
+ # === reset (reset tag)
119
+ # ========================================================================= #
120
+ def reset
121
+ reset_the_internal_variables
122
+ # ======================================================================= #
123
+ # === @configuration
124
+ # ======================================================================= #
125
+ @configuration = [true, __dir__, NAMESPACE]
126
+ title_width_height(TITLE, WIDTH, HEIGHT)
127
+ use_gtk_paradise_project_css_file
128
+ append_project_CSS_file
129
+ # ======================================================================= #
130
+ # === @callback_quit
131
+ # ======================================================================= #
132
+ @callback_quit = Proc.new { quit }
133
+ # ======================================================================= #
134
+ # === @callback_new_file
135
+ # ======================================================================= #
136
+ @callback_new_file = Proc.new { e 'This is supposed to create a new file.' }
137
+ end
138
+
139
+ # ========================================================================= #
140
+ # === synchronize_anti_sense
141
+ #
142
+ # Will fetch content and synchronize the @entry_anti_sense
143
+ # ========================================================================= #
144
+ def synchronize_anti_sense
145
+ this_text = ''.dup
146
+ @entry_sense.text?.each_char { |char|
147
+ case char
148
+ when 'A' then this_text << 'T'
149
+ when 'T' then this_text << 'A'
150
+ when 'C' then this_text << 'G'
151
+ when 'G' then this_text << 'C'
152
+ end
153
+ }
154
+ @entry_anti_sense.set_text(this_text)
155
+ end
156
+
157
+ # ========================================================================= #
158
+ # === create_the_entries (entries tag)
159
+ #
160
+ # The Sense strand has the uppercased ATGC variant.
161
+ # ========================================================================= #
162
+ def create_the_entries
163
+ # ======================================================================= #
164
+ # === @entry_sense
165
+ # ======================================================================= #
166
+ @entry_sense = entry
167
+ @entry_sense.yellow_background
168
+ @entry_sense.bblack1
169
+ @entry_sense.position = 12
170
+ @entry_sense.use_this_font = USE_THIS_FONT
171
+ @entry_sense.on_key_press_event { |w,event|
172
+ handle_sense(event)
173
+ }
174
+ @entry_sense.set_max_length(MAX_LENGTH)
175
+
176
+ # ======================================================================= #
177
+ # === @entry_anti_sense
178
+ # ======================================================================= #
179
+ @entry_anti_sense = entry
180
+ @entry_anti_sense.yellow_background
181
+ @entry_anti_sense.bblack1
182
+ @entry_anti_sense.editable = false
183
+ @entry_anti_sense.use_this_font = USE_THIS_FONT
184
+ @entry_anti_sense.set_max_length(MAX_LENGTH)
185
+ # @entry_anti_sense.on_button_press_event { |w, e|
186
+ # @entry_anti_sense.do_focus
187
+ # # @entry_anti_sense.select_everything
188
+ # }
189
+ end
190
+
191
+ # ========================================================================= #
192
+ # === create_the_boxes
193
+ # ========================================================================= #
194
+ def create_the_boxes
195
+ # ======================================================================= #
196
+ # === @outer_vbox
197
+ # ======================================================================= #
198
+ @outer_vbox = padded_vbox
199
+ @box_with_small_buttons = padded_hbox
200
+ end
201
+
202
+ # ========================================================================= #
203
+ # === padding?
204
+ # ========================================================================= #
205
+ def padding?
206
+ 4
207
+ end
208
+
209
+ # ========================================================================= #
210
+ # === border_size?
211
+ # ========================================================================= #
212
+ def border_size?
213
+ 2
214
+ end
215
+
216
+ # ========================================================================= #
217
+ # === create_the_main_window
218
+ # ========================================================================= #
219
+ def create_the_main_window
220
+ @main_window = window(
221
+ @title,
222
+ @width,
223
+ @height,
224
+ @use_this_as_the_options_hash
225
+ )
226
+ @main_window.enable_free_form_css
227
+ @main_window.try_to_use_this_font(USE_THIS_FONT)
228
+ end
229
+
230
+ # ========================================================================= #
231
+ # === create_the_buttons (buttons tag, button tag)
232
+ #
233
+ # This method will create the various buttons for this application.
234
+ # ========================================================================= #
235
+ def create_the_buttons
236
+ # ======================================================================= #
237
+ # === @button_reset
238
+ # ======================================================================= #
239
+ @button_reset = bold_button('_Reset Sense Anti Sense')
240
+ @button_reset.hint = 'Click on this button to '\
241
+ '<b>reset</b> again to <b>the initial state '\
242
+ 'of this widget</b>.'
243
+ @button_reset.clear_background
244
+ @button_reset.bblack1
245
+ @button_reset.modify_background(:active, :lightblue)
246
+ @button_reset.modify_background(:prelight, :steelblue)
247
+ @button_reset.modify_background(:normal, :lightblue)
248
+ @button_reset.on_clicked {
249
+ on_reset_action_called
250
+ }
251
+ # ======================================================================= #
252
+ # Next add the four buttons for A, T, C and G.
253
+ # ======================================================================= #
254
+ @button_A = coloured_button('A_'+colour_for(:a))
255
+ @button_A.on_clicked { handle_sense('A') }
256
+ @button_A.popup_hint('Add A (for Adenine) to the sense-strand on top.')
257
+ @button_A.bblack1
258
+ @box_with_small_buttons.minimal(@button_A, 2)
259
+
260
+ @button_T = coloured_button('T_'+colour_for(:t))
261
+ @button_T.on_clicked { handle_sense('T') }
262
+ @button_T.popup_hint('Add T (for Thymine) to the sense-strand on top.')
263
+ @button_T.bblack1
264
+ @box_with_small_buttons.minimal(@button_T, 2)
265
+
266
+ @button_C = coloured_button('C_'+colour_for(:c))
267
+ @button_C.on_clicked { handle_sense('C') }
268
+ @button_C.popup_hint('Add C (for Cytosin) to the sense-strand on top.')
269
+ @button_C.bblack1
270
+ @box_with_small_buttons.minimal(@button_C, 2)
271
+
272
+ @button_G = coloured_button('G_'+colour_for(:g))
273
+ @button_G.on_clicked { handle_sense('G') }
274
+ @button_G.popup_hint('Add G (for Guanine) to the sense-strand on top.')
275
+ @button_G.bblack1
276
+ @box_with_small_buttons.minimal(@button_G, 2)
277
+ do_style_all_the_buttons
278
+ end
279
+
280
+ # ========================================================================= #
281
+ # === do_style_all_the_buttons
282
+ # ========================================================================= #
283
+ def do_style_all_the_buttons(
284
+ i = return_all_buttons
285
+ )
286
+ i.each {|this_button|
287
+ this_button.set_name('button1')
288
+ this_button.bblack2
289
+ }
290
+ end
291
+
292
+ # ========================================================================= #
293
+ # === colour_for
294
+ #
295
+ # Use this method to return a colour for the 4 nucleotides.
296
+ # ========================================================================= #
297
+ def colour_for(i)
298
+ case i
299
+ when :a
300
+ 'whitesmoke'
301
+ when :t
302
+ 'teal'
303
+ when :c
304
+ 'slateblue'
305
+ when :g
306
+ 'red'
307
+ end
308
+ end
309
+
310
+ # ========================================================================= #
311
+ # === on_reset_action_called
312
+ # ========================================================================= #
313
+ def on_reset_action_called
314
+ # e 'Cleaning up.' # <- If we want to be extra-chatty.
315
+ @entry_sense.set_text('')
316
+ @entry_anti_sense.set_text('')
317
+ @entry_sense.set_focus(true)
318
+ @entry_sense.position = 12
319
+ end
320
+
321
+ # ========================================================================= #
322
+ # === focus
323
+ #
324
+ # Use this method to focus.
325
+ # ========================================================================= #
326
+ def focus(where)
327
+ case where
328
+ when ':left'
329
+ @entry_sense.set_focus(true)
330
+ when ':right'
331
+ @entry_anti_sense.set_focus(true)
332
+ end
333
+ end
334
+
335
+ # ========================================================================= #
336
+ # === connect_skeleton (connect tag)
337
+ # ========================================================================= #
338
+ def connect_skeleton
339
+ abort_on_exception
340
+ end
341
+
342
+ # ========================================================================= #
343
+ # === create_and_add_menu (menu tag)
344
+ # ========================================================================= #
345
+ def create_and_add_menu
346
+ return # This is currently not in use. Perhaps at a later time.
347
+ @menu_bar = gtk_menu_bar
348
+ @menu_item1 = gtk_menu_item('Options')
349
+ @menu_item1.set_submenu(@first_submenu = gtk_menu)
350
+ @menu_bar.append(@menu_item1)
351
+ @menu_actions = [
352
+ ['FileMenu', nil, '_File'],
353
+ ['Quit', ::Gtk::Stock::QUIT, '_Quit', 'Q', 'Quit', @callback_quit],
354
+ ['New', ::Gtk::Stock::NEW, '_New', 'N', 'Create a new file', @callback_new_file]
355
+ ]
356
+ end
357
+
358
+ # ========================================================================= #
359
+ # === create_the_grid (grid tag)
360
+ # ========================================================================= #
361
+ def create_the_grid
362
+ # ======================================================================= #
363
+ # Use a table for the main UI.
364
+ # ======================================================================= #
365
+ @grid = default_grid
366
+ @grid.set_column_spacing(3)
367
+ @grid.set_row_spacing(3)
368
+ @grid.pad10px
369
+ end
370
+
371
+ # ========================================================================= #
372
+ # === populate_the_grid
373
+ # ========================================================================= #
374
+ def populate_the_grid
375
+ label_sense = bold_label('SENSE')
376
+ @grid.left(label_sense)
377
+ @grid.right(@entry_sense)
378
+ label_antisense = bold_label('ANTISENSE')
379
+ # Next comes a hbox with an image, which is located in the middle.
380
+ hbox_with_entry_sense_and_image = hbox
381
+ hbox_with_entry_sense_and_image.add(label_antisense)
382
+ # The image in the middle.
383
+ @image = image(IMG_DNA_HELIX)
384
+ if @image
385
+ @eventbox = event_box(@image)
386
+ # ======================================================================= #
387
+ # === @eventbox
388
+ #
389
+ # It is associated with an Eventbox. When we click with a mouse button
390
+ # on that image in the middle, the following code will be run.
391
+ # ======================================================================= #
392
+ @eventbox.signal_connect(:event) { |widget, event|
393
+ case event.event_type.name.to_s
394
+ when 'GDK_BUTTON_PRESS'
395
+ if event.button == 1 # left mouse click
396
+ _ = @entry_sense.text # Feedback the current content.
397
+ e _
398
+ if Object.const_defined? :XorgBuffer
399
+ XorgBuffer[_.chomp]
400
+ end
401
+ elsif event.button == 2 # middle mouse click
402
+ elsif event.button == 3 # right mouse click
403
+ _ = @entry_anti_sense.text
404
+ e _
405
+ end
406
+ if respond_to? :gdk_selection_clipboard
407
+ @clipboard = widget.get_clipboard(gdk_selection_clipboard)
408
+ @clipboard.text = _
409
+ @clipboard.request_text { |clipboard, text, data|
410
+ # p text # zb label.set_text(text)
411
+ }
412
+ @entry_anti_sense.paste_clipboard
413
+ end
414
+ end
415
+ }
416
+ hbox_with_entry_sense_and_image.add(@eventbox)
417
+ end
418
+ @grid.left(hbox_with_entry_sense_and_image)
419
+ @grid.right(@entry_anti_sense)
420
+ @grid.left(@box_with_small_buttons)
421
+ @grid.right(@button_reset)
422
+ end
423
+
424
+ # ========================================================================= #
425
+ # === create_skeleton (create tag)
426
+ # ========================================================================= #
427
+ def create_skeleton
428
+ create_the_boxes
429
+ create_the_main_window
430
+ create_the_entries
431
+ create_the_buttons # Must come before the main table
432
+ create_the_grid
433
+ create_and_add_menu if use_gtk3?
434
+ end
435
+
436
+ # ========================================================================= #
437
+ # === run (run tag)
438
+ # ========================================================================= #
439
+ def run
440
+ if use_gtk3?
441
+ require 'gtk_paradise/requires/require_the_base_module.rb'
442
+ # extend ::Gtk::BaseModule
443
+ end
444
+ create_skeleton
445
+ # if use_gtk3?
446
+ # @outer_vbox.minimal(@menu_bar, 5) # Keep the menu bar small.
447
+ # end
448
+ @outer_vbox.minimal(hsep)
449
+ text_on_top = text(TITLE)
450
+ text_on_top.align_to_the_left
451
+ @outer_vbox.minimal(text_on_top)
452
+
453
+ # ======================================================================= #
454
+ # === Handle libui first
455
+ # ======================================================================= #
456
+ if is_libui_in_use?
457
+ elsif is_gtk_in_use?
458
+ end
459
+
460
+ populate_the_grid
461
+ @outer_vbox.maximal(@grid, 5)
462
+ @main_window.add(@outer_vbox)
463
+ @main_window.try_to_add_default_CSS_rules
464
+ @main_window.intelligent_exit
465
+ @main_window.show_all
466
+ connect_skeleton
467
+ set_use_this_font(USE_THIS_FONT) if use_gtk3?
468
+ infer_the_size_automatically
469
+ if use_gtk3?
470
+ require 'gtk_paradise/run'
471
+ _ = @main_window
472
+ r = ::Gtk.run
473
+ r << _
474
+ r.background_colour(:linen)
475
+ r.automatic_size_then_automatic_title
476
+ r.top_left_then_run
477
+ else
478
+ run_main
479
+ end
480
+ end
481
+
482
+ # ========================================================================= #
483
+ # === handle_sense
484
+ #
485
+ # You can send it an event, or a string.
486
+ # ========================================================================= #
487
+ def handle_sense(event)
488
+ old_text = @entry_sense.text?.dup # stores old text
489
+ # ======================================================================= #
490
+ # Store as upcased input:
491
+ # ======================================================================= #
492
+ if use_gtk?
493
+ if event.class == ::Gdk::EventKey
494
+ event = ::Gdk::Keyval.to_name(event.keyval).upcase
495
+ else
496
+ event = event.upcase
497
+ end
498
+ case old_text
499
+ when 'A' then event = 'A'
500
+ when 'T' then event = 'T'
501
+ when 'C' then event = 'C'
502
+ when 'G' then event = 'G'
503
+ else # do nothing
504
+ end
505
+ else
506
+ event = event.dup if event.frozen?
507
+ event.upcase!
508
+ end
509
+ @entry_sense.set_text(
510
+ "#{old_text}#{event}"
511
+ )
512
+ synchronize_anti_sense
513
+ end
514
+
515
+ end; end; end
516
+
517
+ if __FILE__ == $PROGRAM_NAME
518
+ Bioroebe::GUI::AntiSenseStrand.new(ARGV)
519
+ end
Binary file
@@ -0,0 +1,6 @@
1
+ This directory may contain some java code, but do not expect
2
+ bioroebe to ever be fully written in Java.
3
+
4
+ To compile it anew, do:
5
+
6
+ run bioroebe/AllInOne.java