bioroebe 0.10.80

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Files changed (802) hide show
  1. checksums.yaml +7 -0
  2. data/LICENSE.md +428 -0
  3. data/README.md +9280 -0
  4. data/bin/advanced_dotplot +7 -0
  5. data/bin/align_open_reading_frames +12 -0
  6. data/bin/all_positions_of_this_nucleotide +7 -0
  7. data/bin/aminoacid_composition +7 -0
  8. data/bin/aminoacid_frequencies +12 -0
  9. data/bin/aminoacid_substitution +7 -0
  10. data/bin/automatically_rename_this_fasta_file +7 -0
  11. data/bin/base_composition +7 -0
  12. data/bin/batch_create_windows_executables +7 -0
  13. data/bin/biomart_console +11 -0
  14. data/bin/bioroebe +27 -0
  15. data/bin/bioroebe_controller +10 -0
  16. data/bin/bioshell +26 -0
  17. data/bin/blosum_2D_table +12 -0
  18. data/bin/calculate_n50_value +12 -0
  19. data/bin/chunked_display +12 -0
  20. data/bin/codon_frequency +9 -0
  21. data/bin/codon_to_aminoacid +30 -0
  22. data/bin/colourize_this_fasta_sequence +14 -0
  23. data/bin/compact_fasta_file +7 -0
  24. data/bin/complement +7 -0
  25. data/bin/complementary_dna_strand +12 -0
  26. data/bin/complementary_rna_strand +12 -0
  27. data/bin/compseq +7 -0
  28. data/bin/consensus_sequence +17 -0
  29. data/bin/count_AT +12 -0
  30. data/bin/count_GC +12 -0
  31. data/bin/create_random_aminoacids +7 -0
  32. data/bin/decode_this_aminoacid_sequence +20 -0
  33. data/bin/deduce_aminoacid_sequence +13 -0
  34. data/bin/deduce_most_likely_aminoacid_sequence +7 -0
  35. data/bin/display_aminoacid_table +12 -0
  36. data/bin/display_open_reading_frames +7 -0
  37. data/bin/dna_to_aminoacid_sequence +7 -0
  38. data/bin/dna_to_rna +7 -0
  39. data/bin/downcase_chunked_display +12 -0
  40. data/bin/download_this_pdb +7 -0
  41. data/bin/fasta_index +7 -0
  42. data/bin/fetch_data_from_uniprot +12 -0
  43. data/bin/filter_away_invalid_nucleotides +12 -0
  44. data/bin/find_substring +19 -0
  45. data/bin/genbank_to_fasta +7 -0
  46. data/bin/hamming_distance +12 -0
  47. data/bin/input_as_dna +12 -0
  48. data/bin/is_palindrome +13 -0
  49. data/bin/leading_five_prime +7 -0
  50. data/bin/levensthein +7 -0
  51. data/bin/longest_ORF +14 -0
  52. data/bin/longest_substring +12 -0
  53. data/bin/n_stop_codons_in_this_sequence +15 -0
  54. data/bin/open_reading_frames +14 -0
  55. data/bin/overwrite_fasta_header +7 -0
  56. data/bin/palindrome_2D_structure +7 -0
  57. data/bin/palindrome_generator +7 -0
  58. data/bin/parse_fasta +7 -0
  59. data/bin/partner_nucleotide +9 -0
  60. data/bin/possible_codons_for_this_aminoacid +12 -0
  61. data/bin/random_dna_sequence +12 -0
  62. data/bin/random_sequence +12 -0
  63. data/bin/raw_hamming_distance +12 -0
  64. data/bin/return_longest_substring_via_LCS_algorithm +7 -0
  65. data/bin/reverse_complement +7 -0
  66. data/bin/reverse_sequence +7 -0
  67. data/bin/ruler +12 -0
  68. data/bin/scan_this_input_for_startcodons +12 -0
  69. data/bin/short_aminoacid_letter_from_long_aminoacid_name +7 -0
  70. data/bin/show_atomic_composition +7 -0
  71. data/bin/show_codon_usage +12 -0
  72. data/bin/show_fasta_header +7 -0
  73. data/bin/show_nucleotide_sequence +7 -0
  74. data/bin/show_this_codon_table +7 -0
  75. data/bin/show_this_dna_sequence +7 -0
  76. data/bin/showorf +14 -0
  77. data/bin/simplify_fasta +7 -0
  78. data/bin/sort_aminoacid_based_on_its_hydrophobicity +7 -0
  79. data/bin/split_this_fasta_file_into_chromosomes +7 -0
  80. data/bin/strict_filter_away_invalid_aminoacids +7 -0
  81. data/bin/taxonomy +63 -0
  82. data/bin/three_to_one +7 -0
  83. data/bin/to_rna +7 -0
  84. data/bin/trailing_three_prime +7 -0
  85. data/bin/trypsin_digest +7 -0
  86. data/bin/upcase_this_aminoacid_sequence_and_remove_numbers +7 -0
  87. data/bioroebe.gemspec +97 -0
  88. data/doc/IUPAC_aminoacids_code.md +36 -0
  89. data/doc/IUPAC_nucleotide_code.md +19 -0
  90. data/doc/README.gen +9237 -0
  91. data/doc/blosum.md +5 -0
  92. data/doc/compatibility/BIO_PHP.md +37 -0
  93. data/doc/compatibility/README.md +3 -0
  94. data/doc/compatibility/emboss.md +56 -0
  95. data/doc/extensive_usage_example.md +35 -0
  96. data/doc/german_names_for_the_aminoacids.md +27 -0
  97. data/doc/instructions_for_the_taxonomy_subproject.md +504 -0
  98. data/doc/legacy_paths.md +9 -0
  99. data/doc/pdb_ATOM_entry.md +33 -0
  100. data/doc/quality_control/README.md +2 -0
  101. data/doc/quality_control/commandline_applications.md +13 -0
  102. data/doc/resources.md +23 -0
  103. data/doc/setup.rb +1655 -0
  104. data/doc/statistics/statistics.md +41 -0
  105. data/doc/todo/README.md +5 -0
  106. data/doc/todo/bioroebe_GUI_todo.md +15 -0
  107. data/doc/todo/bioroebe_todo.md +2823 -0
  108. data/doc/using_biomart.md +258 -0
  109. data/html/test.html +144 -0
  110. data/lib/bioroebe/aminoacids/aminoacid_substitution.rb +118 -0
  111. data/lib/bioroebe/aminoacids/aminoacids_mass_table.rb +118 -0
  112. data/lib/bioroebe/aminoacids/codon_percentage.rb +189 -0
  113. data/lib/bioroebe/aminoacids/colourize_hydrophilic_and_hydrophobic_aminoacids.rb +110 -0
  114. data/lib/bioroebe/aminoacids/create_random_aminoacids.rb +221 -0
  115. data/lib/bioroebe/aminoacids/deduce_aminoacid_sequence.rb +460 -0
  116. data/lib/bioroebe/aminoacids/display_aminoacid_table.rb +231 -0
  117. data/lib/bioroebe/aminoacids/show_hydrophobicity.rb +184 -0
  118. data/lib/bioroebe/annotations/README.md +2 -0
  119. data/lib/bioroebe/annotations/create_annotation_format.rb +208 -0
  120. data/lib/bioroebe/autoinclude.rb +7 -0
  121. data/lib/bioroebe/base/base.rb +35 -0
  122. data/lib/bioroebe/base/colours.rb +14 -0
  123. data/lib/bioroebe/base/colours_for_base/colours_for_base.rb +275 -0
  124. data/lib/bioroebe/base/commandline_application/README.md +7 -0
  125. data/lib/bioroebe/base/commandline_application/aminoacids.rb +33 -0
  126. data/lib/bioroebe/base/commandline_application/commandline_application.rb +37 -0
  127. data/lib/bioroebe/base/commandline_application/commandline_arguments.rb +144 -0
  128. data/lib/bioroebe/base/commandline_application/directory.rb +33 -0
  129. data/lib/bioroebe/base/commandline_application/extract.rb +22 -0
  130. data/lib/bioroebe/base/commandline_application/misc.rb +485 -0
  131. data/lib/bioroebe/base/commandline_application/opn.rb +47 -0
  132. data/lib/bioroebe/base/commandline_application/reset.rb +40 -0
  133. data/lib/bioroebe/base/commandline_application/warnings.rb +36 -0
  134. data/lib/bioroebe/base/commandline_application/write_what_into.rb +29 -0
  135. data/lib/bioroebe/base/initialize.rb +18 -0
  136. data/lib/bioroebe/base/misc.rb +94 -0
  137. data/lib/bioroebe/base/namespace.rb +16 -0
  138. data/lib/bioroebe/base/prototype/README.md +12 -0
  139. data/lib/bioroebe/base/prototype/e_and_ee.rb +24 -0
  140. data/lib/bioroebe/base/prototype/misc.rb +108 -0
  141. data/lib/bioroebe/base/prototype/mkdir.rb +20 -0
  142. data/lib/bioroebe/base/prototype/prototype.rb +21 -0
  143. data/lib/bioroebe/base/prototype/reset.rb +26 -0
  144. data/lib/bioroebe/base/reset.rb +11 -0
  145. data/lib/bioroebe/biomart/LICENSE.md +27 -0
  146. data/lib/bioroebe/biomart/attribute.rb +77 -0
  147. data/lib/bioroebe/biomart/biomart.rb +227 -0
  148. data/lib/bioroebe/biomart/database.rb +128 -0
  149. data/lib/bioroebe/biomart/dataset.rb +572 -0
  150. data/lib/bioroebe/biomart/filter.rb +97 -0
  151. data/lib/bioroebe/biomart/server.rb +152 -0
  152. data/lib/bioroebe/blosum/blosum.rb +88 -0
  153. data/lib/bioroebe/calculate/calculate_blosum_score.rb +145 -0
  154. data/lib/bioroebe/calculate/calculate_gc_content.rb +301 -0
  155. data/lib/bioroebe/calculate/calculate_levensthein_distance.rb +100 -0
  156. data/lib/bioroebe/calculate/calculate_melting_temperature.rb +398 -0
  157. data/lib/bioroebe/calculate/calculate_melting_temperature_for_more_than_thirteen_nucleotides.rb +304 -0
  158. data/lib/bioroebe/calculate/calculate_the_position_specific_scoring_matrix.rb +166 -0
  159. data/lib/bioroebe/cell/README.md +1 -0
  160. data/lib/bioroebe/cell/cell.rb +63 -0
  161. data/lib/bioroebe/cleave_and_digest/README.md +2 -0
  162. data/lib/bioroebe/cleave_and_digest/cleave.rb +80 -0
  163. data/lib/bioroebe/cleave_and_digest/digestion.rb +75 -0
  164. data/lib/bioroebe/cleave_and_digest/trypsin.rb +192 -0
  165. data/lib/bioroebe/codon_tables/README.md +9 -0
  166. data/lib/bioroebe/codon_tables/frequencies/287_Pseudomonas_aeruginosa.yml +101 -0
  167. data/lib/bioroebe/codon_tables/frequencies/3702_Arabidopsis_thaliana.yml +77 -0
  168. data/lib/bioroebe/codon_tables/frequencies/4932_Saccharomyces_cerevisiae.yml +103 -0
  169. data/lib/bioroebe/codon_tables/frequencies/7227_Drosophila_melanogaster.yml +71 -0
  170. data/lib/bioroebe/codon_tables/frequencies/83333_Escherichia_coli_K12.yml +103 -0
  171. data/lib/bioroebe/codon_tables/frequencies/9606_Homo_sapiens.yml +123 -0
  172. data/lib/bioroebe/codon_tables/frequencies/9685_Felis_catus.yml +78 -0
  173. data/lib/bioroebe/codon_tables/frequencies/README.md +10 -0
  174. data/lib/bioroebe/codon_tables/frequencies/parse_frequency_table.rb +337 -0
  175. data/lib/bioroebe/codons/README.md +28 -0
  176. data/lib/bioroebe/codons/codon_table.rb +416 -0
  177. data/lib/bioroebe/codons/codon_tables.rb +123 -0
  178. data/lib/bioroebe/codons/codons.rb +517 -0
  179. data/lib/bioroebe/codons/convert_this_codon_to_that_aminoacid.rb +102 -0
  180. data/lib/bioroebe/codons/detect_minimal_codon.rb +180 -0
  181. data/lib/bioroebe/codons/determine_optimal_codons.rb +74 -0
  182. data/lib/bioroebe/codons/possible_codons_for_this_aminoacid.rb +380 -0
  183. data/lib/bioroebe/codons/sanitize_codon_frequency.rb +144 -0
  184. data/lib/bioroebe/codons/show_codon_tables.rb +130 -0
  185. data/lib/bioroebe/codons/show_codon_usage.rb +197 -0
  186. data/lib/bioroebe/codons/show_this_codon_table.rb +573 -0
  187. data/lib/bioroebe/codons/start_codons.rb +105 -0
  188. data/lib/bioroebe/colours/colour_schemes/README.md +10 -0
  189. data/lib/bioroebe/colours/colour_schemes/array_available_colour_schemes.rb +38 -0
  190. data/lib/bioroebe/colours/colour_schemes/buried.rb +70 -0
  191. data/lib/bioroebe/colours/colour_schemes/colour_scheme.rb +101 -0
  192. data/lib/bioroebe/colours/colour_schemes/colour_scheme_demo.rb +262 -0
  193. data/lib/bioroebe/colours/colour_schemes/helix.rb +65 -0
  194. data/lib/bioroebe/colours/colour_schemes/hydropathy.rb +70 -0
  195. data/lib/bioroebe/colours/colour_schemes/nucleotide.rb +47 -0
  196. data/lib/bioroebe/colours/colour_schemes/score.rb +112 -0
  197. data/lib/bioroebe/colours/colour_schemes/simple.rb +42 -0
  198. data/lib/bioroebe/colours/colour_schemes/strand.rb +65 -0
  199. data/lib/bioroebe/colours/colour_schemes/taylor.rb +58 -0
  200. data/lib/bioroebe/colours/colour_schemes/turn.rb +65 -0
  201. data/lib/bioroebe/colours/colour_schemes/zappo.rb +59 -0
  202. data/lib/bioroebe/colours/colourize_sequence.rb +262 -0
  203. data/lib/bioroebe/colours/colours.rb +119 -0
  204. data/lib/bioroebe/colours/misc_colours.rb +80 -0
  205. data/lib/bioroebe/colours/rev.rb +41 -0
  206. data/lib/bioroebe/colours/sdir.rb +21 -0
  207. data/lib/bioroebe/colours/sfancy.rb +21 -0
  208. data/lib/bioroebe/colours/sfile.rb +21 -0
  209. data/lib/bioroebe/colours/simp.rb +21 -0
  210. data/lib/bioroebe/colours/swarn.rb +29 -0
  211. data/lib/bioroebe/colours/use_colours.rb +27 -0
  212. data/lib/bioroebe/configuration/configuration.rb +114 -0
  213. data/lib/bioroebe/configuration/constants.rb +35 -0
  214. data/lib/bioroebe/constants/GUIs.rb +79 -0
  215. data/lib/bioroebe/constants/aminoacids_and_proteins.rb +146 -0
  216. data/lib/bioroebe/constants/base_directory.rb +120 -0
  217. data/lib/bioroebe/constants/carriage_return.rb +14 -0
  218. data/lib/bioroebe/constants/codon_tables.rb +77 -0
  219. data/lib/bioroebe/constants/database_constants.rb +107 -0
  220. data/lib/bioroebe/constants/files_and_directories.rb +579 -0
  221. data/lib/bioroebe/constants/misc.rb +189 -0
  222. data/lib/bioroebe/constants/newline.rb +14 -0
  223. data/lib/bioroebe/constants/nucleotides.rb +114 -0
  224. data/lib/bioroebe/constants/regex.rb +28 -0
  225. data/lib/bioroebe/constants/roebe.rb +38 -0
  226. data/lib/bioroebe/constants/row_terminator.rb +16 -0
  227. data/lib/bioroebe/constants/tabulator.rb +14 -0
  228. data/lib/bioroebe/constants/unicode.rb +12 -0
  229. data/lib/bioroebe/constants/urls.rb +50 -0
  230. data/lib/bioroebe/conversions/README.md +3 -0
  231. data/lib/bioroebe/conversions/convert_aminoacid_to_dna.rb +298 -0
  232. data/lib/bioroebe/conversions/dna_to_aminoacid_sequence.rb +569 -0
  233. data/lib/bioroebe/count/README.md +1 -0
  234. data/lib/bioroebe/count/count_amount_of_aminoacids.rb +352 -0
  235. data/lib/bioroebe/count/count_amount_of_nucleotides.rb +491 -0
  236. data/lib/bioroebe/count/count_at.rb +39 -0
  237. data/lib/bioroebe/count/count_gc.rb +43 -0
  238. data/lib/bioroebe/css/README.md +5 -0
  239. data/lib/bioroebe/css/project.css +121 -0
  240. data/lib/bioroebe/data/README.md +10 -0
  241. data/lib/bioroebe/data/bam/README.md +1 -0
  242. data/lib/bioroebe/data/data.txt +192 -0
  243. data/lib/bioroebe/data/fasta/GFP_mutant_3_coding_sequence.fasta +12 -0
  244. data/lib/bioroebe/data/fasta/alu_elements.fasta +42 -0
  245. data/lib/bioroebe/data/fasta/lady_slippers_orchid.fasta +1197 -0
  246. data/lib/bioroebe/data/fasta/loxP.fasta +2 -0
  247. data/lib/bioroebe/data/fasta/ls_orchid.fasta +1197 -0
  248. data/lib/bioroebe/data/fasta/pax6_in_mouse.fasta +1 -0
  249. data/lib/bioroebe/data/fasta/test.fasta +7 -0
  250. data/lib/bioroebe/data/fasta/test_DNA.fasta +1 -0
  251. data/lib/bioroebe/data/fastq/fastq_example_file.fastq +32 -0
  252. data/lib/bioroebe/data/fastq/fastq_example_file_SP1.fastq +1000 -0
  253. data/lib/bioroebe/data/fastq/one_random_fastq_entry.fastq +4 -0
  254. data/lib/bioroebe/data/genbank/sample_file.genbank +15 -0
  255. data/lib/bioroebe/data/genbank/standard.fasta +3 -0
  256. data/lib/bioroebe/data/gff/Escherichia_coli_K12_plasmid_F_DNA_NC_002483.1.gff3 +345 -0
  257. data/lib/bioroebe/data/gff/sample.gff +2 -0
  258. data/lib/bioroebe/data/gff/test_gene.gff +4 -0
  259. data/lib/bioroebe/data/gff/transcripts.gff +16 -0
  260. data/lib/bioroebe/data/gtf/README.md +1 -0
  261. data/lib/bioroebe/data/json/example_config.json +48 -0
  262. data/lib/bioroebe/data/pdb/1VII.pdb +754 -0
  263. data/lib/bioroebe/data/pdb/ala_phe_ala.pdb +228 -0
  264. data/lib/bioroebe/data/pdb/rcsb_pdb_1VII.fasta +2 -0
  265. data/lib/bioroebe/data/phylip/README.md +11 -0
  266. data/lib/bioroebe/data/phylip/example.phylip +7 -0
  267. data/lib/bioroebe/data/svg/example.svg +301 -0
  268. data/lib/bioroebe/databases/README.md +1 -0
  269. data/lib/bioroebe/databases/download_taxonomy_database.rb +102 -0
  270. data/lib/bioroebe/dotplots/README.md +5 -0
  271. data/lib/bioroebe/dotplots/advanced_dotplot.rb +256 -0
  272. data/lib/bioroebe/dotplots/dotplot.rb +184 -0
  273. data/lib/bioroebe/electron_microscopy/coordinate_analyzer.rb +191 -0
  274. data/lib/bioroebe/electron_microscopy/fix_pos_file.rb +102 -0
  275. data/lib/bioroebe/electron_microscopy/generate_em2em_file.rb +122 -0
  276. data/lib/bioroebe/electron_microscopy/parse_coordinates.rb +197 -0
  277. data/lib/bioroebe/electron_microscopy/read_file_xmd.rb +282 -0
  278. data/lib/bioroebe/electron_microscopy/simple_star_file_generator.rb +131 -0
  279. data/lib/bioroebe/encoding/README.md +2 -0
  280. data/lib/bioroebe/encoding/encoding.rb +45 -0
  281. data/lib/bioroebe/enzymes/README.md +2 -0
  282. data/lib/bioroebe/enzymes/has_this_restriction_enzyme.rb +46 -0
  283. data/lib/bioroebe/enzymes/restriction_enzyme.rb +200 -0
  284. data/lib/bioroebe/enzymes/restriction_enzymes_file.rb +72 -0
  285. data/lib/bioroebe/enzymes/return_restriction_enzyme_sequence_and_cut_position.rb +80 -0
  286. data/lib/bioroebe/enzymes/return_sequence_that_is_cut_via_restriction_enzyme.rb +65 -0
  287. data/lib/bioroebe/enzymes/show_restriction_enzymes.rb +119 -0
  288. data/lib/bioroebe/exceptions/README.md +2 -0
  289. data/lib/bioroebe/exceptions/exceptions.rb +17 -0
  290. data/lib/bioroebe/ext/LICENCE.md +5 -0
  291. data/lib/bioroebe/ext/README.md +7 -0
  292. data/lib/bioroebe/ext/main.cpp +45 -0
  293. data/lib/bioroebe/ext/nucleotide.cpp +24 -0
  294. data/lib/bioroebe/ext/nussinov_algorithm.cpp +348 -0
  295. data/lib/bioroebe/ext/sequence +0 -0
  296. data/lib/bioroebe/ext/sequence.cpp +162 -0
  297. data/lib/bioroebe/fasta_and_fastq/README.md +6 -0
  298. data/lib/bioroebe/fasta_and_fastq/autocorrect_the_name_of_this_fasta_file.rb +88 -0
  299. data/lib/bioroebe/fasta_and_fastq/compact_fasta_file/compact_fasta_file.rb +151 -0
  300. data/lib/bioroebe/fasta_and_fastq/display_how_many_fasta_entries_are_in_this_directory.rb +111 -0
  301. data/lib/bioroebe/fasta_and_fastq/download_fasta.rb +248 -0
  302. data/lib/bioroebe/fasta_and_fastq/fasta_defline/README.md +2 -0
  303. data/lib/bioroebe/fasta_and_fastq/fasta_defline/fasta_defline.rb +113 -0
  304. data/lib/bioroebe/fasta_and_fastq/fasta_parser.rb +167 -0
  305. data/lib/bioroebe/fasta_and_fastq/fastq_format_explainer.rb +131 -0
  306. data/lib/bioroebe/fasta_and_fastq/length_modifier/length_modifier.rb +87 -0
  307. data/lib/bioroebe/fasta_and_fastq/parse_fasta/constants.rb +50 -0
  308. data/lib/bioroebe/fasta_and_fastq/parse_fasta/initialize.rb +86 -0
  309. data/lib/bioroebe/fasta_and_fastq/parse_fasta/menu.rb +117 -0
  310. data/lib/bioroebe/fasta_and_fastq/parse_fasta/misc.rb +981 -0
  311. data/lib/bioroebe/fasta_and_fastq/parse_fasta/parse_fasta.rb +27 -0
  312. data/lib/bioroebe/fasta_and_fastq/parse_fasta/report.rb +156 -0
  313. data/lib/bioroebe/fasta_and_fastq/parse_fasta/reset.rb +128 -0
  314. data/lib/bioroebe/fasta_and_fastq/parse_fasta/run.rb +20 -0
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  577. data/lib/bioroebe/svg/track.rb +263 -0
  578. data/lib/bioroebe/taxonomy/README.md +1 -0
  579. data/lib/bioroebe/taxonomy/chart.rb +95 -0
  580. data/lib/bioroebe/taxonomy/class_methods.rb +181 -0
  581. data/lib/bioroebe/taxonomy/colours.rb +26 -0
  582. data/lib/bioroebe/taxonomy/constants.rb +218 -0
  583. data/lib/bioroebe/taxonomy/edit.rb +97 -0
  584. data/lib/bioroebe/taxonomy/help/help.rb +65 -0
  585. data/lib/bioroebe/taxonomy/help/helpline.rb +53 -0
  586. data/lib/bioroebe/taxonomy/info/check_available.rb +143 -0
  587. data/lib/bioroebe/taxonomy/info/info.rb +337 -0
  588. data/lib/bioroebe/taxonomy/info/is_dna.rb +150 -0
  589. data/lib/bioroebe/taxonomy/interactive.rb +1933 -0
  590. data/lib/bioroebe/taxonomy/menu.rb +905 -0
  591. data/lib/bioroebe/taxonomy/node.rb +118 -0
  592. data/lib/bioroebe/taxonomy/parse_fasta.rb +383 -0
  593. data/lib/bioroebe/taxonomy/shared.rb +287 -0
  594. data/lib/bioroebe/taxonomy/taxonomy.rb +521 -0
  595. data/lib/bioroebe/toplevel_methods/ad_hoc_task.rb +56 -0
  596. data/lib/bioroebe/toplevel_methods/aminoacids_and_proteins.rb +715 -0
  597. data/lib/bioroebe/toplevel_methods/atomic_composition.rb +198 -0
  598. data/lib/bioroebe/toplevel_methods/base_composition.rb +121 -0
  599. data/lib/bioroebe/toplevel_methods/blast.rb +153 -0
  600. data/lib/bioroebe/toplevel_methods/calculate_n50_value.rb +57 -0
  601. data/lib/bioroebe/toplevel_methods/cat.rb +71 -0
  602. data/lib/bioroebe/toplevel_methods/chunked_display.rb +92 -0
  603. data/lib/bioroebe/toplevel_methods/cliner.rb +81 -0
  604. data/lib/bioroebe/toplevel_methods/complement.rb +58 -0
  605. data/lib/bioroebe/toplevel_methods/convert_global_env.rb +39 -0
  606. data/lib/bioroebe/toplevel_methods/databases.rb +73 -0
  607. data/lib/bioroebe/toplevel_methods/delimiter.rb +19 -0
  608. data/lib/bioroebe/toplevel_methods/digest.rb +71 -0
  609. data/lib/bioroebe/toplevel_methods/download_and_fetch_data.rb +146 -0
  610. data/lib/bioroebe/toplevel_methods/e.rb +20 -0
  611. data/lib/bioroebe/toplevel_methods/editor.rb +21 -0
  612. data/lib/bioroebe/toplevel_methods/esystem.rb +22 -0
  613. data/lib/bioroebe/toplevel_methods/exponential_growth.rb +74 -0
  614. data/lib/bioroebe/toplevel_methods/extract.rb +56 -0
  615. data/lib/bioroebe/toplevel_methods/fasta_and_fastq.rb +353 -0
  616. data/lib/bioroebe/toplevel_methods/file_and_directory_related_actions.rb +257 -0
  617. data/lib/bioroebe/toplevel_methods/frequencies.rb +92 -0
  618. data/lib/bioroebe/toplevel_methods/hamming_distance.rb +60 -0
  619. data/lib/bioroebe/toplevel_methods/infer.rb +66 -0
  620. data/lib/bioroebe/toplevel_methods/is_on_roebe.rb +39 -0
  621. data/lib/bioroebe/toplevel_methods/leading_five_prime_and_trailing_three_prime.rb +101 -0
  622. data/lib/bioroebe/toplevel_methods/levensthein.rb +63 -0
  623. data/lib/bioroebe/toplevel_methods/log_directory.rb +109 -0
  624. data/lib/bioroebe/toplevel_methods/longest_common_substring.rb +55 -0
  625. data/lib/bioroebe/toplevel_methods/map_ncbi_entry_to_eutils_id.rb +88 -0
  626. data/lib/bioroebe/toplevel_methods/matches.rb +259 -0
  627. data/lib/bioroebe/toplevel_methods/misc.rb +432 -0
  628. data/lib/bioroebe/toplevel_methods/nucleotides.rb +715 -0
  629. data/lib/bioroebe/toplevel_methods/number_of_clones.rb +63 -0
  630. data/lib/bioroebe/toplevel_methods/open_in_browser.rb +77 -0
  631. data/lib/bioroebe/toplevel_methods/open_reading_frames.rb +236 -0
  632. data/lib/bioroebe/toplevel_methods/opn.rb +34 -0
  633. data/lib/bioroebe/toplevel_methods/palindromes.rb +127 -0
  634. data/lib/bioroebe/toplevel_methods/parse.rb +59 -0
  635. data/lib/bioroebe/toplevel_methods/phred_error_probability.rb +68 -0
  636. data/lib/bioroebe/toplevel_methods/rds.rb +24 -0
  637. data/lib/bioroebe/toplevel_methods/remove.rb +86 -0
  638. data/lib/bioroebe/toplevel_methods/return_source_code_of_this_method.rb +35 -0
  639. data/lib/bioroebe/toplevel_methods/return_subsequence_based_on_indices.rb +68 -0
  640. data/lib/bioroebe/toplevel_methods/rna_splicing.rb +73 -0
  641. data/lib/bioroebe/toplevel_methods/rnalfold.rb +69 -0
  642. data/lib/bioroebe/toplevel_methods/searching_and_finding.rb +116 -0
  643. data/lib/bioroebe/toplevel_methods/shuffleseq.rb +37 -0
  644. data/lib/bioroebe/toplevel_methods/statistics.rb +53 -0
  645. data/lib/bioroebe/toplevel_methods/sum_of_odd_integers.rb +62 -0
  646. data/lib/bioroebe/toplevel_methods/taxonomy.rb +187 -0
  647. data/lib/bioroebe/toplevel_methods/three_delimiter.rb +34 -0
  648. data/lib/bioroebe/toplevel_methods/time_and_date.rb +53 -0
  649. data/lib/bioroebe/toplevel_methods/to_camelcase.rb +26 -0
  650. data/lib/bioroebe/toplevel_methods/truncate.rb +48 -0
  651. data/lib/bioroebe/toplevel_methods/url.rb +36 -0
  652. data/lib/bioroebe/toplevel_methods/verbose.rb +59 -0
  653. data/lib/bioroebe/utility_scripts/align_open_reading_frames.rb +191 -0
  654. data/lib/bioroebe/utility_scripts/analyse_local_dataset.rb +119 -0
  655. data/lib/bioroebe/utility_scripts/check_for_mismatches/check_for_mismatches.rb +230 -0
  656. data/lib/bioroebe/utility_scripts/compacter.rb +131 -0
  657. data/lib/bioroebe/utility_scripts/compseq/compseq.rb +529 -0
  658. data/lib/bioroebe/utility_scripts/consensus_sequence.rb +374 -0
  659. data/lib/bioroebe/utility_scripts/create_batch_entrez_file.rb +130 -0
  660. data/lib/bioroebe/utility_scripts/determine_antigenic_areas.rb +115 -0
  661. data/lib/bioroebe/utility_scripts/determine_missing_nucleotides_percentage.rb +137 -0
  662. data/lib/bioroebe/utility_scripts/display_open_reading_frames/determine.rb +73 -0
  663. data/lib/bioroebe/utility_scripts/display_open_reading_frames/display_open_reading_frames.rb +31 -0
  664. data/lib/bioroebe/utility_scripts/display_open_reading_frames/initialize.rb +37 -0
  665. data/lib/bioroebe/utility_scripts/display_open_reading_frames/menu.rb +49 -0
  666. data/lib/bioroebe/utility_scripts/display_open_reading_frames/misc.rb +471 -0
  667. data/lib/bioroebe/utility_scripts/display_open_reading_frames/report.rb +113 -0
  668. data/lib/bioroebe/utility_scripts/display_open_reading_frames/reset.rb +56 -0
  669. data/lib/bioroebe/utility_scripts/dot_alignment.rb +177 -0
  670. data/lib/bioroebe/utility_scripts/download_files_from_rebase.rb +72 -0
  671. data/lib/bioroebe/utility_scripts/find_gene.rb +202 -0
  672. data/lib/bioroebe/utility_scripts/mirror_repeat.rb +235 -0
  673. data/lib/bioroebe/utility_scripts/move_file_to_its_correct_location.rb +151 -0
  674. data/lib/bioroebe/utility_scripts/parse_taxonomy.rb +168 -0
  675. data/lib/bioroebe/utility_scripts/pathways.rb +152 -0
  676. data/lib/bioroebe/utility_scripts/permutations.rb +145 -0
  677. data/lib/bioroebe/utility_scripts/punnet/punnet.rb +126 -0
  678. data/lib/bioroebe/utility_scripts/show_this_dna_sequence.rb +148 -0
  679. data/lib/bioroebe/utility_scripts/showorf/constants.rb +36 -0
  680. data/lib/bioroebe/utility_scripts/showorf/help.rb +33 -0
  681. data/lib/bioroebe/utility_scripts/showorf/initialize.rb +52 -0
  682. data/lib/bioroebe/utility_scripts/showorf/menu.rb +68 -0
  683. data/lib/bioroebe/utility_scripts/showorf/reset.rb +39 -0
  684. data/lib/bioroebe/utility_scripts/showorf/run.rb +152 -0
  685. data/lib/bioroebe/utility_scripts/showorf/show.rb +97 -0
  686. data/lib/bioroebe/utility_scripts/showorf/showorf.rb +488 -0
  687. data/lib/bioroebe/version/version.rb +44 -0
  688. data/lib/bioroebe/viennarna/README.md +3 -0
  689. data/lib/bioroebe/viennarna/rnafold_wrapper.rb +196 -0
  690. data/lib/bioroebe/with_gui.rb +18 -0
  691. data/lib/bioroebe/www/bioroebe.cgi +44 -0
  692. data/lib/bioroebe/www/embeddable_interface.rb +686 -0
  693. data/lib/bioroebe/www/sinatra/sinatra.rb +1013 -0
  694. data/lib/bioroebe/yaml/agarose/agarose_concentrations.yml +21 -0
  695. data/lib/bioroebe/yaml/aminoacids/amino_acids.yml +92 -0
  696. data/lib/bioroebe/yaml/aminoacids/amino_acids_abbreviations.yml +31 -0
  697. data/lib/bioroebe/yaml/aminoacids/amino_acids_average_mass_table.yml +33 -0
  698. data/lib/bioroebe/yaml/aminoacids/amino_acids_classification.yml +18 -0
  699. data/lib/bioroebe/yaml/aminoacids/amino_acids_english.yml +26 -0
  700. data/lib/bioroebe/yaml/aminoacids/amino_acids_frequency.yml +44 -0
  701. data/lib/bioroebe/yaml/aminoacids/amino_acids_long_name_to_one_letter.yml +61 -0
  702. data/lib/bioroebe/yaml/aminoacids/amino_acids_molecular_formula.yml +32 -0
  703. data/lib/bioroebe/yaml/aminoacids/amino_acids_monoisotopic_mass_table.yml +38 -0
  704. data/lib/bioroebe/yaml/aminoacids/amino_acids_reste.yml +35 -0
  705. data/lib/bioroebe/yaml/aminoacids/amino_acids_three_to_one.yml +34 -0
  706. data/lib/bioroebe/yaml/aminoacids/hydropathy_table.yml +44 -0
  707. data/lib/bioroebe/yaml/aminoacids/molecular_weight.yml +29 -0
  708. data/lib/bioroebe/yaml/aminoacids/simple_aminoacids.yml +66 -0
  709. data/lib/bioroebe/yaml/aminoacids/weight_of_common_proteins.yml +33 -0
  710. data/lib/bioroebe/yaml/antisense/antisense.yml +9 -0
  711. data/lib/bioroebe/yaml/base_composition_of_dna.yml +37 -0
  712. data/lib/bioroebe/yaml/blosum/blosum45.yml +36 -0
  713. data/lib/bioroebe/yaml/blosum/blosum50.yml +34 -0
  714. data/lib/bioroebe/yaml/blosum/blosum62.yml +35 -0
  715. data/lib/bioroebe/yaml/blosum/blosum80.yml +37 -0
  716. data/lib/bioroebe/yaml/blosum/blosum90.yml +36 -0
  717. data/lib/bioroebe/yaml/blosum/blosum_matrix.yml +200 -0
  718. data/lib/bioroebe/yaml/chromosomes/chromosome_numbers.yml +30 -0
  719. data/lib/bioroebe/yaml/codon_tables/1.yml +113 -0
  720. data/lib/bioroebe/yaml/codon_tables/10.yml +89 -0
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  732. data/lib/bioroebe/yaml/codon_tables/25.yml +89 -0
  733. data/lib/bioroebe/yaml/codon_tables/26.yml +96 -0
  734. data/lib/bioroebe/yaml/codon_tables/27.yml +104 -0
  735. data/lib/bioroebe/yaml/codon_tables/28.yml +97 -0
  736. data/lib/bioroebe/yaml/codon_tables/29.yml +93 -0
  737. data/lib/bioroebe/yaml/codon_tables/3.yml +98 -0
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  747. data/lib/bioroebe/yaml/configuration/browser.yml +1 -0
  748. data/lib/bioroebe/yaml/configuration/colourize_fasta_sequences.yml +14 -0
  749. data/lib/bioroebe/yaml/configuration/default_colours_for_the_aminoacids.yml +28 -0
  750. data/lib/bioroebe/yaml/configuration/temp_dir.yml +1 -0
  751. data/lib/bioroebe/yaml/configuration/try_to_use_matplotlib.yml +1 -0
  752. data/lib/bioroebe/yaml/configuration/use_opn.yml +1 -0
  753. data/lib/bioroebe/yaml/configuration/use_this_database.yml +1 -0
  754. data/lib/bioroebe/yaml/create_these_directories_on_startup/create_these_directories_on_startup.yml +9 -0
  755. data/lib/bioroebe/yaml/default_dna_input.yml +3 -0
  756. data/lib/bioroebe/yaml/enzymes/enzyme_classes.yml +15 -0
  757. data/lib/bioroebe/yaml/enzymes/pH-Optima.yml +11 -0
  758. data/lib/bioroebe/yaml/fasta_and_fastq/fastq_quality_schemes.yml +44 -0
  759. data/lib/bioroebe/yaml/genomes/README.md +16 -0
  760. data/lib/bioroebe/yaml/humans/README.md +2 -0
  761. data/lib/bioroebe/yaml/humans/human_chromosomes.yml +53 -0
  762. data/lib/bioroebe/yaml/laboratory/README.md +1 -0
  763. data/lib/bioroebe/yaml/laboratory/pipettes.yml +8 -0
  764. data/lib/bioroebe/yaml/mRNA/mRNA.yml +16 -0
  765. data/lib/bioroebe/yaml/nuclear_localization_sequences.yml +15 -0
  766. data/lib/bioroebe/yaml/nucleotides/abbreviations_for_nucleotides.yml +29 -0
  767. data/lib/bioroebe/yaml/nucleotides/nucleotide_density.yml +10 -0
  768. data/lib/bioroebe/yaml/nucleotides/nucleotides.yml +34 -0
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  770. data/lib/bioroebe/yaml/pathways/README.md +2 -0
  771. data/lib/bioroebe/yaml/pathways/citric_acid_cycle.yml +16 -0
  772. data/lib/bioroebe/yaml/pathways/glycolysis.yml +20 -0
  773. data/lib/bioroebe/yaml/pathways/shikimate_pathway.yml +23 -0
  774. data/lib/bioroebe/yaml/pathways/urea_cycle.yml +11 -0
  775. data/lib/bioroebe/yaml/primers/README.md +4 -0
  776. data/lib/bioroebe/yaml/primers/primers.yml +3 -0
  777. data/lib/bioroebe/yaml/promoters/35S.yml +15 -0
  778. data/lib/bioroebe/yaml/promoters/strong_promoters.yml +24 -0
  779. data/lib/bioroebe/yaml/proteases/proteases.yml +3 -0
  780. data/lib/bioroebe/yaml/proteins/ubiquitin.yml +4 -0
  781. data/lib/bioroebe/yaml/remote_urls/README.md +4 -0
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  785. data/lib/bioroebe/yaml/sequences/README.md +2 -0
  786. data/lib/bioroebe/yaml/talens.yml +22 -0
  787. data/lib/bioroebe/yaml/viruses/ecoli_phages.yml +63 -0
  788. data/lib/bioroebe/yaml/viruses/viruses.yml +6 -0
  789. data/lib/bioroebe.rb +5 -0
  790. data/spec/testing_toplevel_method_editor.rb +20 -0
  791. data/spec/testing_toplevel_method_url.rb +15 -0
  792. data/spec/testing_toplevel_method_verbose.rb +13 -0
  793. data/test/advanced_svg_example.rb +307 -0
  794. data/test/testing_bioroebe.rb +25 -0
  795. data/test/testing_codons.rb +45 -0
  796. data/test/testing_dna_to_rna_conversion.rb +15 -0
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  798. data/test/testing_reverse_complement.rb +32 -0
  799. data/test/testing_svg_component_of_bioroebe.rb +311 -0
  800. data/test/testing_svg_component_of_bioroebe_from_json_dataset.rb +34 -0
  801. data/test/testing_taxonomy.rb +22 -0
  802. metadata +1059 -0
@@ -0,0 +1,370 @@
1
+ #!/usr/bin/ruby -w
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+ # Encoding: UTF-8
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+ # frozen_string_literal: true
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+ # =========================================================================== #
5
+ # === Bioroebe::GUI::Gtk::HammingDistance
6
+ # =========================================================================== #
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+ # require 'bioroebe/gui/gtk3/hamming_distance/hamming_distance.rb'
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+ # Bioroebe::GUI::Gtk::HammingDistance.run
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+ # =========================================================================== #
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+ require 'gtk_paradise/require_gtk3'
11
+ require 'bioroebe/constants/GUIs.rb'
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+
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+ module Bioroebe
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+
15
+ module GUI
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+
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+ module Gtk
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+
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+ class HammingDistance < ::Gtk::Box # === Bioroebe::GUI::Gtk::HammingDistance
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+
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+ require 'bioroebe/string_matching/hamming_distance.rb'
22
+ require 'bioroebe/gui/shared_code/levensthein_distance/levensthein_distance_module.rb'
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+
24
+ require 'gtk_paradise/requires/require_the_base_module.rb'
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+ include ::Gtk::BaseModule
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+
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+ # ========================================================================= #
28
+ # === NAMESPACE
29
+ # ========================================================================= #
30
+ NAMESPACE = inspect
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+
32
+ # ========================================================================= #
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+ # === WIDTH
34
+ # ========================================================================= #
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+ WIDTH = 500
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+
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+ # ========================================================================= #
38
+ # === HEIGHT
39
+ # ========================================================================= #
40
+ HEIGHT = 320
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+
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+ # ========================================================================= #
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+ # === TITLE
44
+ #
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+ # Specify which title to use for this small widget.
46
+ # ========================================================================= #
47
+ TITLE = 'Hamming Distance'
48
+ USE_THIS_TITLE = TITLE # === USE_THIS_TITLE
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+
50
+ # ========================================================================= #
51
+ # === PADDING_TO_USE
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+ # ========================================================================= #
53
+ PADDING_TO_USE = 5
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+
55
+ # ========================================================================= #
56
+ # === MONOSPACED_FONT
57
+ #
58
+ # When this font is changed, don't forget to also change the font
59
+ # at SMALLER_FONT.
60
+ # ========================================================================= #
61
+ MONOSPACED_FONT = :hack_20
62
+ USE_THIS_FONT = MONOSPACED_FONT
63
+
64
+ # ========================================================================= #
65
+ # === SMALLER_FONT
66
+ # ========================================================================= #
67
+ SMALLER_FONT = :hack_16
68
+
69
+ # ========================================================================= #
70
+ # === DEFAULT_TEXT_FOR_ENTRY1
71
+ # ========================================================================= #
72
+ DEFAULT_TEXT_FOR_ENTRY1 = 'AGUUCGAUGGAAAATAT'
73
+
74
+ # ========================================================================= #
75
+ # === DEFAULT_TEXT_FOR_ENTRY2
76
+ # ========================================================================= #
77
+ DEFAULT_TEXT_FOR_ENTRY2 = 'AGUCCGGUCGAAAAAAA'
78
+
79
+ # ========================================================================= #
80
+ # === initialize
81
+ # ========================================================================= #
82
+ def initialize(
83
+ optional_commandline_arguments = nil,
84
+ run_already = true
85
+ )
86
+ super(:horizontal)
87
+ register_sigint
88
+ reset
89
+ set_title(USE_THIS_TITLE) if respond_to?(:set_title)
90
+ if optional_commandline_arguments and respond_to?(:menu)
91
+ menu(optional_commandline_arguments)
92
+ end
93
+ signal_destroy_then_quit
94
+ run if run_already
95
+ end
96
+
97
+ # ========================================================================= #
98
+ # === reset (reset tag)
99
+ # ========================================================================= #
100
+ def reset
101
+ reset_the_internal_variables
102
+ # ======================================================================= #
103
+ # === @configuration
104
+ # ======================================================================= #
105
+ @configuration = [true, __dir__, NAMESPACE]
106
+ title_width_height_font(TITLE, WIDTH, HEIGHT, USE_THIS_FONT)
107
+ use_gtk_paradise_project_CSS_file
108
+ append_project_CSS_file
109
+ set_border_width(5)
110
+ infer_the_size_automatically
111
+ end
112
+
113
+ # ========================================================================= #
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+ # === padding?
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+ # ========================================================================= #
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+ def padding?
117
+ PADDING_TO_USE
118
+ end
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+
120
+ # ========================================================================= #
121
+ # === border_size?
122
+ # ========================================================================= #
123
+ def border_size?
124
+ 0
125
+ end
126
+
127
+ # ========================================================================= #
128
+ # === seq1?
129
+ # ========================================================================= #
130
+ def seq1?
131
+ @entry_on_top.text
132
+ end
133
+
134
+ # ========================================================================= #
135
+ # === seq2?
136
+ # ========================================================================= #
137
+ def seq2?
138
+ @entry_on_bottom.text
139
+ end
140
+
141
+ # ========================================================================= #
142
+ # === set_minimum_size
143
+ # ========================================================================= #
144
+ def set_minimum_size
145
+ set_size_request(80, 100)
146
+ end
147
+
148
+ # ========================================================================= #
149
+ # === entry1?
150
+ # ========================================================================= #
151
+ def entry1?
152
+ @entry_on_top
153
+ end
154
+
155
+ # ========================================================================= #
156
+ # === compare_the_two_sequences
157
+ #
158
+ # This is the method that will compare the two sequences.
159
+ # ========================================================================= #
160
+ def compare_the_two_sequences
161
+ hamming_distance_object = ::Bioroebe::HammingDistance.new("#{seq1?} #{seq2?}") { :be_quiet }
162
+ @entry_n_differences.set_text(
163
+ hamming_distance_object.n_differences?.to_s
164
+ )
165
+ end; alias do_compare compare_the_two_sequences # === do_compare
166
+ alias do_calculate_the_differences compare_the_two_sequences # === do_calculate_the_differences
167
+
168
+ # ========================================================================= #
169
+ # === consider_sanitizing_the_input
170
+ # ========================================================================= #
171
+ def consider_sanitizing_the_input
172
+ # ======================================================================= #
173
+ # The following two lines were added as of 07.05.2020.
174
+ # ======================================================================= #
175
+ @entry_on_top.set_text(@entry_on_top.text.delete('-'))
176
+ @entry_on_bottom.set_text(@entry_on_bottom.text.delete('-'))
177
+ end
178
+
179
+ # ========================================================================= #
180
+ # === create_entries (entries tag, entry tag)
181
+ # ========================================================================= #
182
+ def create_entries
183
+ # ======================================================================= #
184
+ # === @entry_n_differences
185
+ #
186
+ # This is the entry that will simply show the number of differences
187
+ # between the two sequences, as a number.
188
+ # ======================================================================= #
189
+ @entry_n_differences = gtk_entry_with_icon_name('edit-undo-symbolic-rtl.symbolic')
190
+ @entry_n_differences.xalign = 0.5 # Align towards the center.
191
+ @entry_n_differences.bblack1
192
+ @entry_n_differences.clear_background
193
+ @entry_n_differences.yellow_background
194
+
195
+ # ======================================================================= #
196
+ # === @entry_on_top
197
+ # ======================================================================= #
198
+ @entry_on_top = gtk_entry(DEFAULT_TEXT_FOR_ENTRY1)
199
+ @entry_on_top.set_font(MONOSPACED_FONT)
200
+ @entry_on_top.clear_background
201
+ @entry_on_top.css_class('BG_lightsteelblue')
202
+ @entry_on_top.bblack1
203
+ @entry_on_top.on_changed { do_calculate_the_differences }
204
+ @entry_on_top.hint = 'This entry should contain the first sequence (seq1).'
205
+ @entry_on_top.set_max_length(50_000)
206
+ @entry_on_top.on_key_press_event { |widget, event|
207
+ old_text = widget.text
208
+ keyname = Gdk::Keyval.to_name(event.keyval)
209
+ case keyname.upcase
210
+ when *%w( A T C G U )
211
+ # This is ok.
212
+ when *%w( B D E F H I J K L M N O P Q R S V W X Y Z ) # Otherwise set the old input here.
213
+ unless event.state.control_mask? # This snippet checks whether a key-combination has been used.
214
+ widget.set_text(old_text)
215
+ end
216
+ end
217
+ }
218
+ # ======================================================================= #
219
+ # And keep things upcased here:
220
+ # ======================================================================= #
221
+ @entry_on_top.on_key_release { |widget, event|
222
+ old_text = @entry_on_top.text
223
+ new_text = @entry_on_top.text.upcase
224
+ unless old_text == new_text
225
+ @entry_on_top.set_text(new_text)
226
+ @entry_on_top.move_cursor_to_the_most_right_position
227
+ end
228
+ }
229
+
230
+ # ======================================================================= #
231
+ # === @entry_on_bottom
232
+ # ======================================================================= #
233
+ @entry_on_bottom = gtk_entry(DEFAULT_TEXT_FOR_ENTRY2)
234
+ @entry_on_bottom.set_font(MONOSPACED_FONT)
235
+ @entry_on_bottom.css_classes('clear_background BG_lightsteelblue')
236
+ @entry_on_bottom.bblack1
237
+ @entry_on_bottom.on_changed { do_calculate_the_differences }
238
+ @entry_on_bottom.hint = 'This entry should contain the second sequence (seq2).'
239
+ @entry_on_bottom.set_max_length(50_000)
240
+ end
241
+
242
+ # ========================================================================= #
243
+ # === create_compare_button
244
+ #
245
+ # This method will create the button that will compare the two sequences.
246
+ # ========================================================================= #
247
+ def create_compare_button
248
+ # ======================================================================= #
249
+ # === @compare_button
250
+ # ======================================================================= #
251
+ @compare_button = bold_button(::Bioroebe::GUI::LevenstheinDistanceModule::TEXT_COMPARE_THE_TWO_SEQUENCES)
252
+ @compare_button.apply_markup
253
+ @compare_button.lightblue
254
+ @compare_button.set_name('button1')
255
+ @compare_button.hint = 'Click this button to '\
256
+ '<span weight="bold" foreground="lightblue">compare</span> '\
257
+ 'the two sequences.'
258
+ @compare_button.on_clicked {
259
+ consider_sanitizing_the_input
260
+ compare_the_two_sequences
261
+ }
262
+ end
263
+
264
+ # ========================================================================= #
265
+ # === create_skeleton (create tag, skeleton tag)
266
+ # ========================================================================= #
267
+ def create_skeleton
268
+ create_entries
269
+ # ======================================================================= #
270
+ # === The top box
271
+ # ======================================================================= #
272
+ @top_box = gtk_vbox
273
+
274
+ @label_on_top = bold_label(USE_THIS_TITLE)
275
+ @label_on_top.fancy_tooltips =
276
+ "Only <b>valid nucleotides</b> (A, T, C, G, U) \n"\
277
+ "can be accepted as input."
278
+ # ======================================================================= #
279
+ # Create the top hbox for string1 next:
280
+ # ======================================================================= #
281
+ @hbox_for_string1 = gtk_hbox
282
+ @hbox_for_string1.minimal(gtk_label('1').make_bold, 1)
283
+ @hbox_for_string1.maximal(@entry_on_top, 1)
284
+
285
+ # ======================================================================= #
286
+ # Create the bottom hbox for string2 next:
287
+ # ======================================================================= #
288
+ @hbox_for_string2 = gtk_hbox
289
+ @hbox_for_string2.minimal(gtk_label('2').make_bold, 1)
290
+ @hbox_for_string2.maximal(@entry_on_bottom, 1)
291
+
292
+ create_compare_button
293
+
294
+ small_hbox = gtk_hbox
295
+ # ======================================================================= #
296
+ # === n_differences found Gtk::Text
297
+ # ======================================================================= #
298
+ short_text_widget = gtk_text('<b>n differences</b> found:')
299
+ short_text_widget.do_markify
300
+ small_hbox.minimal(short_text_widget, 2)
301
+ small_hbox.hint =
302
+ 'This entry will show <b>how many differences</b> '\
303
+ 'exist between these two strings.'
304
+ small_hbox.minimal(@entry_n_differences, 2)
305
+ # ======================================================================= #
306
+ # === The bottom box
307
+ # ======================================================================= #
308
+ @bottom_box = gtk_vbox
309
+ @bottom_box.pack_start(@compare_button, expand: false, fill: false, padding: 1)
310
+ @bottom_box.pack_start(small_hbox, expand: false, fill: true, padding: 0)
311
+ end
312
+
313
+ # ========================================================================= #
314
+ # === connect_skeleton (connect tag)
315
+ # ========================================================================= #
316
+ def connect_skeleton
317
+ abort_on_exception
318
+ # ======================================================================= #
319
+ # @top_box is an instance of gtk-vbox.
320
+ # ======================================================================= #
321
+ @top_box.minimal(@label_on_top, 1)
322
+ text = left_aligned_text(
323
+ "The <b>Hamming distance</b> - a number - measures the number of "\
324
+ "\npositions at which two strings of equal length are "\
325
+ "different.")
326
+ text.use_this_font = SMALLER_FONT
327
+ @top_box.minimal(text, 12)
328
+ @top_box.minimal(@hbox_for_string1, 2)
329
+ @top_box.minimal(@hbox_for_string2, 2)
330
+
331
+ vpaned = mouse_draggable_via_up_and_down_movement(@top_box, @bottom_box)
332
+ vpaned.set_size_request(@width, 550)
333
+ maximal(vpaned, 8)
334
+ show_all
335
+ end
336
+
337
+ # ========================================================================= #
338
+ # === run (run tag)
339
+ # ========================================================================= #
340
+ def run
341
+ create_skeleton_then_connect_skeleton
342
+ set_minimum_size
343
+ Thread.new {
344
+ sleep 0.01
345
+ @entry_n_differences.do_focus
346
+ entry1?.deselect
347
+ do_compare
348
+ }
349
+ end
350
+
351
+ # ========================================================================= #
352
+ # === Bioroebe::GUI::Gtk::HammingDistance.run
353
+ # ========================================================================= #
354
+ def self.run(
355
+ i = ARGV
356
+ )
357
+ require 'gtk_paradise/run'
358
+ _ = ::Bioroebe::GUI::Gtk::HammingDistance.new(i)
359
+ r = ::Gtk.run
360
+ r << _
361
+ r.modify_background(:normal, :mintcream)
362
+ r.automatic_size_then_automatic_title
363
+ r.top_left_then_run
364
+ end; self.instance_eval { alias run_gtk3_widget run } # === Bioroebe::GUI::Gtk::HammingDistance.run_gtk3_widget
365
+
366
+ end; end; end; end
367
+
368
+ if __FILE__ == $PROGRAM_NAME
369
+ Bioroebe::GUI::Gtk::HammingDistance.run
370
+ end # gtkhammingdistance
@@ -0,0 +1,6 @@
1
+ width: 920
2
+ height: 640
3
+ padding: 4
4
+ title: Levensthein Distance
5
+ favicon: :tabble
6
+ font_in_use: Sans 20
@@ -0,0 +1,175 @@
1
+ #!/usr/bin/ruby -w
2
+ # Encoding: UTF-8
3
+ # frozen_string_literal: true
4
+ # =========================================================================== #
5
+ # === Bioroebe::GUI::Gtk::LevenstheinDistance
6
+ #
7
+ # This is just a small widget that bundles together a GUI component
8
+ # towards the Levensthein class.
9
+ # =========================================================================== #
10
+ # require 'bioroebe/gui/gtk3/levensthein_distance/levensthein_distance.rb'
11
+ # Bioroebe::GUI::Gtk::LevenstheinDistance.run
12
+ # =========================================================================== #
13
+ require 'gtk_paradise/require_gtk3'
14
+
15
+ module Bioroebe
16
+
17
+ module GUI
18
+
19
+ module Gtk
20
+
21
+ class LevenstheinDistance < ::Gtk::Box # === Bioroebe::GUI::Gtk::LevenstheinDistance
22
+
23
+ require 'bioroebe/gui/shared_code/levensthein_distance/levensthein_distance_module.rb'
24
+ include Bioroebe::GUI::LevenstheinDistanceModule
25
+
26
+ require 'gtk_paradise/requires/require_the_base_module.rb'
27
+ include ::Gtk::BaseModule
28
+
29
+ # ========================================================================= #
30
+ # === NAMESPACE
31
+ # ========================================================================= #
32
+ NAMESPACE = inspect
33
+
34
+ # ========================================================================= #
35
+ # === initialize
36
+ # ========================================================================= #
37
+ def initialize(
38
+ commandline_arguments = ARGV,
39
+ run_already = true
40
+ )
41
+ super(:vertical)
42
+ register_sigint
43
+ reset
44
+ set_commandline_arguments(
45
+ commandline_arguments
46
+ )
47
+ modify_background(
48
+ :normal, USE_THIS_AS_BACKGROUND_COLOUR_FOR_THE_WIDGET
49
+ )
50
+ run if run_already
51
+ end
52
+
53
+ # ========================================================================= #
54
+ # === reset (reset tag)
55
+ # ========================================================================= #
56
+ def reset
57
+ reset_the_internal_variables
58
+ # ======================================================================= #
59
+ # === @configuration
60
+ # ======================================================================= #
61
+ @configuration = [true, __dir__, NAMESPACE]
62
+ title_width_height_font(TITLE, WIDTH, HEIGHT, USE_THIS_FONT)
63
+ use_gtk_paradise_project_CSS_file
64
+ append_project_CSS_file
65
+ infer_the_size_automatically
66
+ instantiate_a_new_levensthein_object
67
+ end
68
+
69
+ # ========================================================================= #
70
+ # === create_the_grid (grid tag)
71
+ # ========================================================================= #
72
+ def create_the_grid
73
+ # ======================================================================= #
74
+ # === @grid
75
+ # ======================================================================= #
76
+ @grid = gtk_grid
77
+ @grid.set_column_spacing(4)
78
+ @grid.set_row_spacing(4)
79
+ end
80
+
81
+ # ========================================================================= #
82
+ # === populate_the_grid
83
+ # ========================================================================= #
84
+ def populate_the_grid
85
+ @grid.left(@text1)
86
+ @grid.right(@input_field_for_matches)
87
+ @grid.new_row
88
+ @grid.left(@text2)
89
+ @grid.right(@input_field_for_mismatches)
90
+ @grid.new_row
91
+ @grid.left(@text3)
92
+ @grid.right(@input_field_for_gap_cost)
93
+ end
94
+
95
+ # ========================================================================= #
96
+ # === connect_skeleton (connect tag)
97
+ # ========================================================================= #
98
+ def connect_skeleton
99
+ abort_on_exception
100
+ populate_the_grid
101
+ minimal(@grid, 4)
102
+ if levensthein_object?.sequence1?
103
+ unless levensthein_object?.sequence1?.empty?
104
+ @input_for_string1.set_text(levensthein_object?.sequence1?)
105
+ end
106
+ end
107
+ if levensthein_object?.sequence2?
108
+ unless levensthein_object?.sequence2?.empty?
109
+ @input_for_string2.set_text(levensthein_object?.sequence2?)
110
+ end
111
+ end
112
+ minimal(@input_for_string1, 4)
113
+ minimal(@input_for_string2, 4)
114
+ # ======================================================================= #
115
+ # Next below these two input-fields we will add more info:
116
+ # ======================================================================= #
117
+ small_label = return_the_edit_distance_label
118
+ @hbox_with_the_label_for_the_edit_distance = return_hbox_containing_the_edit_distance(
119
+ small_label, @label_for_the_edit_distance
120
+ )
121
+ @hbox4 = return_hbox4(
122
+ @label_for_the_total_score
123
+ )
124
+ minimal(@hbox_with_the_label_for_the_edit_distance, 4)
125
+ minimal(@hbox4, 4)
126
+ button_box = gtk_button_box(
127
+ @button_compare_the_two_strings
128
+ ) { :spread }
129
+ minimal(button_box, 4)
130
+ end
131
+
132
+ # ========================================================================= #
133
+ # === create_skeleton (create tag)
134
+ # ========================================================================= #
135
+ def create_skeleton
136
+ create_the_entries
137
+ create_the_labels
138
+ create_the_grid
139
+ create_the_first_row
140
+ create_the_second_row
141
+ create_the_third_row
142
+ create_the_buttons
143
+ end
144
+
145
+ # ========================================================================= #
146
+ # === run (run tag)
147
+ # ========================================================================= #
148
+ def run
149
+ create_skeleton_then_connect_skeleton
150
+ show_all
151
+ check_for_commandline_arguments
152
+ do_compare_the_two_sequences
153
+ let_the_fist_entry_respond_to_on_changed_events
154
+ end
155
+
156
+ # ========================================================================= #
157
+ # === Bioroebe::GUI::Gtk::LevenstheinDistance.run
158
+ # ========================================================================= #
159
+ def self.run(
160
+ i = ARGV
161
+ )
162
+ require 'gtk_paradise/run'
163
+ _ = ::Bioroebe::GUI::Gtk::LevenstheinDistance.new(i)
164
+ r = ::Gtk.run
165
+ r << _
166
+ r.automatic_size_then_automatic_title
167
+ r.top_left_then_run
168
+ end; self.instance_eval { alias start_gui_application run } # === Bioroebe::GUI::Gtk::LevenstheinDistanceModule.start_gui_application
169
+ self.instance_eval { alias run_gtk3_widget run } # === Bioroebe::GUI::Gtk::LevenstheinDistance.run_gtk3_widget
170
+
171
+ end; end; end; end
172
+
173
+ if __FILE__ == $PROGRAM_NAME
174
+ Bioroebe::GUI::Gtk::LevenstheinDistance.run
175
+ end