bioroebe 0.10.80

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Files changed (802) hide show
  1. checksums.yaml +7 -0
  2. data/LICENSE.md +428 -0
  3. data/README.md +9280 -0
  4. data/bin/advanced_dotplot +7 -0
  5. data/bin/align_open_reading_frames +12 -0
  6. data/bin/all_positions_of_this_nucleotide +7 -0
  7. data/bin/aminoacid_composition +7 -0
  8. data/bin/aminoacid_frequencies +12 -0
  9. data/bin/aminoacid_substitution +7 -0
  10. data/bin/automatically_rename_this_fasta_file +7 -0
  11. data/bin/base_composition +7 -0
  12. data/bin/batch_create_windows_executables +7 -0
  13. data/bin/biomart_console +11 -0
  14. data/bin/bioroebe +27 -0
  15. data/bin/bioroebe_controller +10 -0
  16. data/bin/bioshell +26 -0
  17. data/bin/blosum_2D_table +12 -0
  18. data/bin/calculate_n50_value +12 -0
  19. data/bin/chunked_display +12 -0
  20. data/bin/codon_frequency +9 -0
  21. data/bin/codon_to_aminoacid +30 -0
  22. data/bin/colourize_this_fasta_sequence +14 -0
  23. data/bin/compact_fasta_file +7 -0
  24. data/bin/complement +7 -0
  25. data/bin/complementary_dna_strand +12 -0
  26. data/bin/complementary_rna_strand +12 -0
  27. data/bin/compseq +7 -0
  28. data/bin/consensus_sequence +17 -0
  29. data/bin/count_AT +12 -0
  30. data/bin/count_GC +12 -0
  31. data/bin/create_random_aminoacids +7 -0
  32. data/bin/decode_this_aminoacid_sequence +20 -0
  33. data/bin/deduce_aminoacid_sequence +13 -0
  34. data/bin/deduce_most_likely_aminoacid_sequence +7 -0
  35. data/bin/display_aminoacid_table +12 -0
  36. data/bin/display_open_reading_frames +7 -0
  37. data/bin/dna_to_aminoacid_sequence +7 -0
  38. data/bin/dna_to_rna +7 -0
  39. data/bin/downcase_chunked_display +12 -0
  40. data/bin/download_this_pdb +7 -0
  41. data/bin/fasta_index +7 -0
  42. data/bin/fetch_data_from_uniprot +12 -0
  43. data/bin/filter_away_invalid_nucleotides +12 -0
  44. data/bin/find_substring +19 -0
  45. data/bin/genbank_to_fasta +7 -0
  46. data/bin/hamming_distance +12 -0
  47. data/bin/input_as_dna +12 -0
  48. data/bin/is_palindrome +13 -0
  49. data/bin/leading_five_prime +7 -0
  50. data/bin/levensthein +7 -0
  51. data/bin/longest_ORF +14 -0
  52. data/bin/longest_substring +12 -0
  53. data/bin/n_stop_codons_in_this_sequence +15 -0
  54. data/bin/open_reading_frames +14 -0
  55. data/bin/overwrite_fasta_header +7 -0
  56. data/bin/palindrome_2D_structure +7 -0
  57. data/bin/palindrome_generator +7 -0
  58. data/bin/parse_fasta +7 -0
  59. data/bin/partner_nucleotide +9 -0
  60. data/bin/possible_codons_for_this_aminoacid +12 -0
  61. data/bin/random_dna_sequence +12 -0
  62. data/bin/random_sequence +12 -0
  63. data/bin/raw_hamming_distance +12 -0
  64. data/bin/return_longest_substring_via_LCS_algorithm +7 -0
  65. data/bin/reverse_complement +7 -0
  66. data/bin/reverse_sequence +7 -0
  67. data/bin/ruler +12 -0
  68. data/bin/scan_this_input_for_startcodons +12 -0
  69. data/bin/short_aminoacid_letter_from_long_aminoacid_name +7 -0
  70. data/bin/show_atomic_composition +7 -0
  71. data/bin/show_codon_usage +12 -0
  72. data/bin/show_fasta_header +7 -0
  73. data/bin/show_nucleotide_sequence +7 -0
  74. data/bin/show_this_codon_table +7 -0
  75. data/bin/show_this_dna_sequence +7 -0
  76. data/bin/showorf +14 -0
  77. data/bin/simplify_fasta +7 -0
  78. data/bin/sort_aminoacid_based_on_its_hydrophobicity +7 -0
  79. data/bin/split_this_fasta_file_into_chromosomes +7 -0
  80. data/bin/strict_filter_away_invalid_aminoacids +7 -0
  81. data/bin/taxonomy +63 -0
  82. data/bin/three_to_one +7 -0
  83. data/bin/to_rna +7 -0
  84. data/bin/trailing_three_prime +7 -0
  85. data/bin/trypsin_digest +7 -0
  86. data/bin/upcase_this_aminoacid_sequence_and_remove_numbers +7 -0
  87. data/bioroebe.gemspec +97 -0
  88. data/doc/IUPAC_aminoacids_code.md +36 -0
  89. data/doc/IUPAC_nucleotide_code.md +19 -0
  90. data/doc/README.gen +9237 -0
  91. data/doc/blosum.md +5 -0
  92. data/doc/compatibility/BIO_PHP.md +37 -0
  93. data/doc/compatibility/README.md +3 -0
  94. data/doc/compatibility/emboss.md +56 -0
  95. data/doc/extensive_usage_example.md +35 -0
  96. data/doc/german_names_for_the_aminoacids.md +27 -0
  97. data/doc/instructions_for_the_taxonomy_subproject.md +504 -0
  98. data/doc/legacy_paths.md +9 -0
  99. data/doc/pdb_ATOM_entry.md +33 -0
  100. data/doc/quality_control/README.md +2 -0
  101. data/doc/quality_control/commandline_applications.md +13 -0
  102. data/doc/resources.md +23 -0
  103. data/doc/setup.rb +1655 -0
  104. data/doc/statistics/statistics.md +41 -0
  105. data/doc/todo/README.md +5 -0
  106. data/doc/todo/bioroebe_GUI_todo.md +15 -0
  107. data/doc/todo/bioroebe_todo.md +2823 -0
  108. data/doc/using_biomart.md +258 -0
  109. data/html/test.html +144 -0
  110. data/lib/bioroebe/aminoacids/aminoacid_substitution.rb +118 -0
  111. data/lib/bioroebe/aminoacids/aminoacids_mass_table.rb +118 -0
  112. data/lib/bioroebe/aminoacids/codon_percentage.rb +189 -0
  113. data/lib/bioroebe/aminoacids/colourize_hydrophilic_and_hydrophobic_aminoacids.rb +110 -0
  114. data/lib/bioroebe/aminoacids/create_random_aminoacids.rb +221 -0
  115. data/lib/bioroebe/aminoacids/deduce_aminoacid_sequence.rb +460 -0
  116. data/lib/bioroebe/aminoacids/display_aminoacid_table.rb +231 -0
  117. data/lib/bioroebe/aminoacids/show_hydrophobicity.rb +184 -0
  118. data/lib/bioroebe/annotations/README.md +2 -0
  119. data/lib/bioroebe/annotations/create_annotation_format.rb +208 -0
  120. data/lib/bioroebe/autoinclude.rb +7 -0
  121. data/lib/bioroebe/base/base.rb +35 -0
  122. data/lib/bioroebe/base/colours.rb +14 -0
  123. data/lib/bioroebe/base/colours_for_base/colours_for_base.rb +275 -0
  124. data/lib/bioroebe/base/commandline_application/README.md +7 -0
  125. data/lib/bioroebe/base/commandline_application/aminoacids.rb +33 -0
  126. data/lib/bioroebe/base/commandline_application/commandline_application.rb +37 -0
  127. data/lib/bioroebe/base/commandline_application/commandline_arguments.rb +144 -0
  128. data/lib/bioroebe/base/commandline_application/directory.rb +33 -0
  129. data/lib/bioroebe/base/commandline_application/extract.rb +22 -0
  130. data/lib/bioroebe/base/commandline_application/misc.rb +485 -0
  131. data/lib/bioroebe/base/commandline_application/opn.rb +47 -0
  132. data/lib/bioroebe/base/commandline_application/reset.rb +40 -0
  133. data/lib/bioroebe/base/commandline_application/warnings.rb +36 -0
  134. data/lib/bioroebe/base/commandline_application/write_what_into.rb +29 -0
  135. data/lib/bioroebe/base/initialize.rb +18 -0
  136. data/lib/bioroebe/base/misc.rb +94 -0
  137. data/lib/bioroebe/base/namespace.rb +16 -0
  138. data/lib/bioroebe/base/prototype/README.md +12 -0
  139. data/lib/bioroebe/base/prototype/e_and_ee.rb +24 -0
  140. data/lib/bioroebe/base/prototype/misc.rb +108 -0
  141. data/lib/bioroebe/base/prototype/mkdir.rb +20 -0
  142. data/lib/bioroebe/base/prototype/prototype.rb +21 -0
  143. data/lib/bioroebe/base/prototype/reset.rb +26 -0
  144. data/lib/bioroebe/base/reset.rb +11 -0
  145. data/lib/bioroebe/biomart/LICENSE.md +27 -0
  146. data/lib/bioroebe/biomart/attribute.rb +77 -0
  147. data/lib/bioroebe/biomart/biomart.rb +227 -0
  148. data/lib/bioroebe/biomart/database.rb +128 -0
  149. data/lib/bioroebe/biomart/dataset.rb +572 -0
  150. data/lib/bioroebe/biomart/filter.rb +97 -0
  151. data/lib/bioroebe/biomart/server.rb +152 -0
  152. data/lib/bioroebe/blosum/blosum.rb +88 -0
  153. data/lib/bioroebe/calculate/calculate_blosum_score.rb +145 -0
  154. data/lib/bioroebe/calculate/calculate_gc_content.rb +301 -0
  155. data/lib/bioroebe/calculate/calculate_levensthein_distance.rb +100 -0
  156. data/lib/bioroebe/calculate/calculate_melting_temperature.rb +398 -0
  157. data/lib/bioroebe/calculate/calculate_melting_temperature_for_more_than_thirteen_nucleotides.rb +304 -0
  158. data/lib/bioroebe/calculate/calculate_the_position_specific_scoring_matrix.rb +166 -0
  159. data/lib/bioroebe/cell/README.md +1 -0
  160. data/lib/bioroebe/cell/cell.rb +63 -0
  161. data/lib/bioroebe/cleave_and_digest/README.md +2 -0
  162. data/lib/bioroebe/cleave_and_digest/cleave.rb +80 -0
  163. data/lib/bioroebe/cleave_and_digest/digestion.rb +75 -0
  164. data/lib/bioroebe/cleave_and_digest/trypsin.rb +192 -0
  165. data/lib/bioroebe/codon_tables/README.md +9 -0
  166. data/lib/bioroebe/codon_tables/frequencies/287_Pseudomonas_aeruginosa.yml +101 -0
  167. data/lib/bioroebe/codon_tables/frequencies/3702_Arabidopsis_thaliana.yml +77 -0
  168. data/lib/bioroebe/codon_tables/frequencies/4932_Saccharomyces_cerevisiae.yml +103 -0
  169. data/lib/bioroebe/codon_tables/frequencies/7227_Drosophila_melanogaster.yml +71 -0
  170. data/lib/bioroebe/codon_tables/frequencies/83333_Escherichia_coli_K12.yml +103 -0
  171. data/lib/bioroebe/codon_tables/frequencies/9606_Homo_sapiens.yml +123 -0
  172. data/lib/bioroebe/codon_tables/frequencies/9685_Felis_catus.yml +78 -0
  173. data/lib/bioroebe/codon_tables/frequencies/README.md +10 -0
  174. data/lib/bioroebe/codon_tables/frequencies/parse_frequency_table.rb +337 -0
  175. data/lib/bioroebe/codons/README.md +28 -0
  176. data/lib/bioroebe/codons/codon_table.rb +416 -0
  177. data/lib/bioroebe/codons/codon_tables.rb +123 -0
  178. data/lib/bioroebe/codons/codons.rb +517 -0
  179. data/lib/bioroebe/codons/convert_this_codon_to_that_aminoacid.rb +102 -0
  180. data/lib/bioroebe/codons/detect_minimal_codon.rb +180 -0
  181. data/lib/bioroebe/codons/determine_optimal_codons.rb +74 -0
  182. data/lib/bioroebe/codons/possible_codons_for_this_aminoacid.rb +380 -0
  183. data/lib/bioroebe/codons/sanitize_codon_frequency.rb +144 -0
  184. data/lib/bioroebe/codons/show_codon_tables.rb +130 -0
  185. data/lib/bioroebe/codons/show_codon_usage.rb +197 -0
  186. data/lib/bioroebe/codons/show_this_codon_table.rb +573 -0
  187. data/lib/bioroebe/codons/start_codons.rb +105 -0
  188. data/lib/bioroebe/colours/colour_schemes/README.md +10 -0
  189. data/lib/bioroebe/colours/colour_schemes/array_available_colour_schemes.rb +38 -0
  190. data/lib/bioroebe/colours/colour_schemes/buried.rb +70 -0
  191. data/lib/bioroebe/colours/colour_schemes/colour_scheme.rb +101 -0
  192. data/lib/bioroebe/colours/colour_schemes/colour_scheme_demo.rb +262 -0
  193. data/lib/bioroebe/colours/colour_schemes/helix.rb +65 -0
  194. data/lib/bioroebe/colours/colour_schemes/hydropathy.rb +70 -0
  195. data/lib/bioroebe/colours/colour_schemes/nucleotide.rb +47 -0
  196. data/lib/bioroebe/colours/colour_schemes/score.rb +112 -0
  197. data/lib/bioroebe/colours/colour_schemes/simple.rb +42 -0
  198. data/lib/bioroebe/colours/colour_schemes/strand.rb +65 -0
  199. data/lib/bioroebe/colours/colour_schemes/taylor.rb +58 -0
  200. data/lib/bioroebe/colours/colour_schemes/turn.rb +65 -0
  201. data/lib/bioroebe/colours/colour_schemes/zappo.rb +59 -0
  202. data/lib/bioroebe/colours/colourize_sequence.rb +262 -0
  203. data/lib/bioroebe/colours/colours.rb +119 -0
  204. data/lib/bioroebe/colours/misc_colours.rb +80 -0
  205. data/lib/bioroebe/colours/rev.rb +41 -0
  206. data/lib/bioroebe/colours/sdir.rb +21 -0
  207. data/lib/bioroebe/colours/sfancy.rb +21 -0
  208. data/lib/bioroebe/colours/sfile.rb +21 -0
  209. data/lib/bioroebe/colours/simp.rb +21 -0
  210. data/lib/bioroebe/colours/swarn.rb +29 -0
  211. data/lib/bioroebe/colours/use_colours.rb +27 -0
  212. data/lib/bioroebe/configuration/configuration.rb +114 -0
  213. data/lib/bioroebe/configuration/constants.rb +35 -0
  214. data/lib/bioroebe/constants/GUIs.rb +79 -0
  215. data/lib/bioroebe/constants/aminoacids_and_proteins.rb +146 -0
  216. data/lib/bioroebe/constants/base_directory.rb +120 -0
  217. data/lib/bioroebe/constants/carriage_return.rb +14 -0
  218. data/lib/bioroebe/constants/codon_tables.rb +77 -0
  219. data/lib/bioroebe/constants/database_constants.rb +107 -0
  220. data/lib/bioroebe/constants/files_and_directories.rb +579 -0
  221. data/lib/bioroebe/constants/misc.rb +189 -0
  222. data/lib/bioroebe/constants/newline.rb +14 -0
  223. data/lib/bioroebe/constants/nucleotides.rb +114 -0
  224. data/lib/bioroebe/constants/regex.rb +28 -0
  225. data/lib/bioroebe/constants/roebe.rb +38 -0
  226. data/lib/bioroebe/constants/row_terminator.rb +16 -0
  227. data/lib/bioroebe/constants/tabulator.rb +14 -0
  228. data/lib/bioroebe/constants/unicode.rb +12 -0
  229. data/lib/bioroebe/constants/urls.rb +50 -0
  230. data/lib/bioroebe/conversions/README.md +3 -0
  231. data/lib/bioroebe/conversions/convert_aminoacid_to_dna.rb +298 -0
  232. data/lib/bioroebe/conversions/dna_to_aminoacid_sequence.rb +569 -0
  233. data/lib/bioroebe/count/README.md +1 -0
  234. data/lib/bioroebe/count/count_amount_of_aminoacids.rb +352 -0
  235. data/lib/bioroebe/count/count_amount_of_nucleotides.rb +491 -0
  236. data/lib/bioroebe/count/count_at.rb +39 -0
  237. data/lib/bioroebe/count/count_gc.rb +43 -0
  238. data/lib/bioroebe/css/README.md +5 -0
  239. data/lib/bioroebe/css/project.css +121 -0
  240. data/lib/bioroebe/data/README.md +10 -0
  241. data/lib/bioroebe/data/bam/README.md +1 -0
  242. data/lib/bioroebe/data/data.txt +192 -0
  243. data/lib/bioroebe/data/fasta/GFP_mutant_3_coding_sequence.fasta +12 -0
  244. data/lib/bioroebe/data/fasta/alu_elements.fasta +42 -0
  245. data/lib/bioroebe/data/fasta/lady_slippers_orchid.fasta +1197 -0
  246. data/lib/bioroebe/data/fasta/loxP.fasta +2 -0
  247. data/lib/bioroebe/data/fasta/ls_orchid.fasta +1197 -0
  248. data/lib/bioroebe/data/fasta/pax6_in_mouse.fasta +1 -0
  249. data/lib/bioroebe/data/fasta/test.fasta +7 -0
  250. data/lib/bioroebe/data/fasta/test_DNA.fasta +1 -0
  251. data/lib/bioroebe/data/fastq/fastq_example_file.fastq +32 -0
  252. data/lib/bioroebe/data/fastq/fastq_example_file_SP1.fastq +1000 -0
  253. data/lib/bioroebe/data/fastq/one_random_fastq_entry.fastq +4 -0
  254. data/lib/bioroebe/data/genbank/sample_file.genbank +15 -0
  255. data/lib/bioroebe/data/genbank/standard.fasta +3 -0
  256. data/lib/bioroebe/data/gff/Escherichia_coli_K12_plasmid_F_DNA_NC_002483.1.gff3 +345 -0
  257. data/lib/bioroebe/data/gff/sample.gff +2 -0
  258. data/lib/bioroebe/data/gff/test_gene.gff +4 -0
  259. data/lib/bioroebe/data/gff/transcripts.gff +16 -0
  260. data/lib/bioroebe/data/gtf/README.md +1 -0
  261. data/lib/bioroebe/data/json/example_config.json +48 -0
  262. data/lib/bioroebe/data/pdb/1VII.pdb +754 -0
  263. data/lib/bioroebe/data/pdb/ala_phe_ala.pdb +228 -0
  264. data/lib/bioroebe/data/pdb/rcsb_pdb_1VII.fasta +2 -0
  265. data/lib/bioroebe/data/phylip/README.md +11 -0
  266. data/lib/bioroebe/data/phylip/example.phylip +7 -0
  267. data/lib/bioroebe/data/svg/example.svg +301 -0
  268. data/lib/bioroebe/databases/README.md +1 -0
  269. data/lib/bioroebe/databases/download_taxonomy_database.rb +102 -0
  270. data/lib/bioroebe/dotplots/README.md +5 -0
  271. data/lib/bioroebe/dotplots/advanced_dotplot.rb +256 -0
  272. data/lib/bioroebe/dotplots/dotplot.rb +184 -0
  273. data/lib/bioroebe/electron_microscopy/coordinate_analyzer.rb +191 -0
  274. data/lib/bioroebe/electron_microscopy/fix_pos_file.rb +102 -0
  275. data/lib/bioroebe/electron_microscopy/generate_em2em_file.rb +122 -0
  276. data/lib/bioroebe/electron_microscopy/parse_coordinates.rb +197 -0
  277. data/lib/bioroebe/electron_microscopy/read_file_xmd.rb +282 -0
  278. data/lib/bioroebe/electron_microscopy/simple_star_file_generator.rb +131 -0
  279. data/lib/bioroebe/encoding/README.md +2 -0
  280. data/lib/bioroebe/encoding/encoding.rb +45 -0
  281. data/lib/bioroebe/enzymes/README.md +2 -0
  282. data/lib/bioroebe/enzymes/has_this_restriction_enzyme.rb +46 -0
  283. data/lib/bioroebe/enzymes/restriction_enzyme.rb +200 -0
  284. data/lib/bioroebe/enzymes/restriction_enzymes_file.rb +72 -0
  285. data/lib/bioroebe/enzymes/return_restriction_enzyme_sequence_and_cut_position.rb +80 -0
  286. data/lib/bioroebe/enzymes/return_sequence_that_is_cut_via_restriction_enzyme.rb +65 -0
  287. data/lib/bioroebe/enzymes/show_restriction_enzymes.rb +119 -0
  288. data/lib/bioroebe/exceptions/README.md +2 -0
  289. data/lib/bioroebe/exceptions/exceptions.rb +17 -0
  290. data/lib/bioroebe/ext/LICENCE.md +5 -0
  291. data/lib/bioroebe/ext/README.md +7 -0
  292. data/lib/bioroebe/ext/main.cpp +45 -0
  293. data/lib/bioroebe/ext/nucleotide.cpp +24 -0
  294. data/lib/bioroebe/ext/nussinov_algorithm.cpp +348 -0
  295. data/lib/bioroebe/ext/sequence +0 -0
  296. data/lib/bioroebe/ext/sequence.cpp +162 -0
  297. data/lib/bioroebe/fasta_and_fastq/README.md +6 -0
  298. data/lib/bioroebe/fasta_and_fastq/autocorrect_the_name_of_this_fasta_file.rb +88 -0
  299. data/lib/bioroebe/fasta_and_fastq/compact_fasta_file/compact_fasta_file.rb +151 -0
  300. data/lib/bioroebe/fasta_and_fastq/display_how_many_fasta_entries_are_in_this_directory.rb +111 -0
  301. data/lib/bioroebe/fasta_and_fastq/download_fasta.rb +248 -0
  302. data/lib/bioroebe/fasta_and_fastq/fasta_defline/README.md +2 -0
  303. data/lib/bioroebe/fasta_and_fastq/fasta_defline/fasta_defline.rb +113 -0
  304. data/lib/bioroebe/fasta_and_fastq/fasta_parser.rb +167 -0
  305. data/lib/bioroebe/fasta_and_fastq/fastq_format_explainer.rb +131 -0
  306. data/lib/bioroebe/fasta_and_fastq/length_modifier/length_modifier.rb +87 -0
  307. data/lib/bioroebe/fasta_and_fastq/parse_fasta/constants.rb +50 -0
  308. data/lib/bioroebe/fasta_and_fastq/parse_fasta/initialize.rb +86 -0
  309. data/lib/bioroebe/fasta_and_fastq/parse_fasta/menu.rb +117 -0
  310. data/lib/bioroebe/fasta_and_fastq/parse_fasta/misc.rb +981 -0
  311. data/lib/bioroebe/fasta_and_fastq/parse_fasta/parse_fasta.rb +27 -0
  312. data/lib/bioroebe/fasta_and_fastq/parse_fasta/report.rb +156 -0
  313. data/lib/bioroebe/fasta_and_fastq/parse_fasta/reset.rb +128 -0
  314. data/lib/bioroebe/fasta_and_fastq/parse_fasta/run.rb +20 -0
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  693. data/lib/bioroebe/www/sinatra/sinatra.rb +1013 -0
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  758. data/lib/bioroebe/yaml/fasta_and_fastq/fastq_quality_schemes.yml +44 -0
  759. data/lib/bioroebe/yaml/genomes/README.md +16 -0
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  762. data/lib/bioroebe/yaml/laboratory/README.md +1 -0
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  791. data/spec/testing_toplevel_method_url.rb +15 -0
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  793. data/test/advanced_svg_example.rb +307 -0
  794. data/test/testing_bioroebe.rb +25 -0
  795. data/test/testing_codons.rb +45 -0
  796. data/test/testing_dna_to_rna_conversion.rb +15 -0
  797. data/test/testing_parse_pdb_file.rb +23 -0
  798. data/test/testing_reverse_complement.rb +32 -0
  799. data/test/testing_svg_component_of_bioroebe.rb +311 -0
  800. data/test/testing_svg_component_of_bioroebe_from_json_dataset.rb +34 -0
  801. data/test/testing_taxonomy.rb +22 -0
  802. metadata +1059 -0
@@ -0,0 +1,128 @@
1
+ #!/usr/bin/ruby -w
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+ # Encoding: UTF-8
3
+ # frozen_string_literal: true
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+ # =========================================================================== #
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+ # === Bioroebe::Biomart::Dataset
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+ #
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+ # Class representation for a biomart database.
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+ #
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+ # Will contain many Biomart::Dataset objects, and belong to
10
+ # a Biomart::Server.
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+ # =========================================================================== #
12
+ module Bioroebe
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+
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+ module Biomart
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+
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+ class Database # === Bioroebe::Biomart::Dataset
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+
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+ include Biomart
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+
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+ # ========================================================================= #
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+ # === initialize
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+ # ========================================================================= #
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+ def initialize( url, args )
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+ @url = url or raise ArgumentError, 'must pass :url'
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+ unless @url =~ /martservice/
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+ @url = @url+'/martservice'
27
+ end
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+ @name = args['name'] || args[:name]
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+ @display_name = args['displayName'] || args[:display_name]
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+ @visible = ( args['visible'] || args[:visible] ) ? true : false
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+ reset
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+ end
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+
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+ # ========================================================================= #
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+ # === reset
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+ # ========================================================================= #
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+ def reset
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+ @datasets = {}
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+ end
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+
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+ # ========================================================================= #
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+ # === visible?
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+ # ========================================================================= #
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+ def visible?
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+ @visible
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+ end; alias visible visible? # === visible
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+
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+ # ========================================================================= #
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+ # === list_datasets
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+ #
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+ # Returns an array of the dataset names (biomart 'name')
52
+ # for this dataset.
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+ #
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+ # @return [Array] An array of dataset names.
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+ # ========================================================================= #
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+ def list_datasets
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+ if @datasets.empty?
58
+ fetch_datasets
59
+ end
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+ return @datasets.keys
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+ end
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+
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+ # ========================================================================= #
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+ # === name?
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+ # ========================================================================= #
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+ def name?
67
+ @name
68
+ end; alias name name? # === name
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+
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+ # ========================================================================= #
71
+ # === datasets?
72
+ #
73
+ # Returns a hash (keyed by the biomart 'name' for the dataset)
74
+ # of all of the Biomart::Dataset objects belonging to this server.
75
+ #
76
+ # @return [Hash] A hash of Biomart::Dataset objects keyed by 'name'
77
+ # ========================================================================= #
78
+ def datasets?
79
+ if @datasets.empty?
80
+ fetch_datasets
81
+ end
82
+ return @datasets
83
+ end; alias datasets datasets? # === dataset
84
+
85
+ # ========================================================================= #
86
+ # === visible?
87
+ #
88
+ # Returns true / false if this database is visbile in the
89
+ # default MartView interface.
90
+ #
91
+ # @return [Boolean] true/false
92
+ # ========================================================================= #
93
+ def visible?
94
+ @visible
95
+ end
96
+
97
+ # ========================================================================= #
98
+ # === fetch_datasets
99
+ #
100
+ # Utility method to do the webservice call to the biomart server and
101
+ # collate/build the information about the datasets.
102
+ # ========================================================================= #
103
+ def fetch_datasets
104
+ url = @url + "?type=datasets&mart=#{@name}"
105
+ document = request( :url => url )
106
+ tsv_data = []
107
+ # Ruby >= 1.9 CSV code.
108
+ tsv_data = CSV.parse( document, { col_sep: "\t" } )
109
+ tsv_data.each { |t|
110
+ if t[1] and ( t[3] === '1' )
111
+ dataset_attr = {
112
+ 'name' => t[1],
113
+ 'displayName' => t[2],
114
+ 'visible' => t[3]
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+ }
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+ @datasets[ dataset_attr['name'] ] = Dataset.new( @url, dataset_attr )
117
+ end
118
+ }
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+ end; private :fetch_datasets
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+
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+ # ========================================================================= #
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+ # === display_name?
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+ # ========================================================================= #
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+ def display_name?
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+ @display_name
126
+ end; alias display_name display_name? # === display_name
127
+
128
+ end; end; end
@@ -0,0 +1,572 @@
1
+ #!/usr/bin/ruby -w
2
+ # Encoding: UTF-8
3
+ # frozen_string_literal: true
4
+ # =========================================================================== #
5
+ # === Bioroebe::Biomart::Dataset
6
+ #
7
+ # Class represetation for a biomart dataset.
8
+ #
9
+ # Can belong to a Biomart::Database and a Biomart::Server.
10
+ # =========================================================================== #
11
+ module Bioroebe
12
+
13
+ module Biomart
14
+
15
+ class Dataset # === Bioroebe::Biomart::Dataset
16
+
17
+ include Biomart
18
+
19
+ attr_reader :display_name
20
+
21
+ # ========================================================================= #
22
+ # === initialize
23
+ #
24
+ # Creates a new Biomart::Dataset object.
25
+ #
26
+ # @param [String] url The URL location of the biomart server.
27
+ # @param [Hash] args An arguments hash giving details of the dataset.
28
+ #
29
+ # arguments hash:
30
+ #
31
+ # {
32
+ # :name => String, #
33
+ # "name" => String, #
34
+ # :display_name => {} #
35
+ #
36
+ # }
37
+ # ========================================================================= #
38
+ def initialize(url, args)
39
+ @url = url or raise ArgumentError, 'must pass :url'
40
+ unless @url =~ /martservice/
41
+ @url = @url+'/martservice'
42
+ end
43
+
44
+ @name = args['name'] || args[:name]
45
+ @display_name = args['displayName'] || args[:display_name]
46
+ @visible = ( args["visible"] || args[:visible] ) ? true : false
47
+ reset
48
+ end
49
+
50
+ # ========================================================================= #
51
+ # === reset (reset tag)
52
+ # ========================================================================= #
53
+ def reset
54
+ # ======================================================================= #
55
+ # === @filters
56
+ # ======================================================================= #
57
+ @filters = {}
58
+ # ======================================================================= #
59
+ # === @attributes
60
+ # ======================================================================= #
61
+ @attributes = {}
62
+ # ======================================================================= #
63
+ # === @importables
64
+ # ======================================================================= #
65
+ @importables = {}
66
+ # ======================================================================= #
67
+ # === @exportables
68
+ # ======================================================================= #
69
+ @exportables = {}
70
+ end
71
+
72
+ # ========================================================================= #
73
+ # === visible?
74
+ # ========================================================================= #
75
+ def visible?
76
+ @visible
77
+ end; alias visible visible? # === visible
78
+
79
+ # ========================================================================= #
80
+ # === filters?
81
+ #
82
+ # Returns a hash (keyed by the biomart 'internal_name' for the filter)
83
+ # of all of the Biomart::Filter objects belonging to this dataset.
84
+ #
85
+ # @return [Hash] A hash of Biomart::Filter objects keyed by 'internal_name'
86
+ # ========================================================================= #
87
+ def filters?
88
+ if @filters.empty?
89
+ fetch_configuration()
90
+ end
91
+ return @filters
92
+ end; alias filters filters? # === filters
93
+
94
+ # ========================================================================= #
95
+ # === list_filters
96
+ #
97
+ # Returns an array of the filter names (biomart 'internal_name')
98
+ # for this dataset.
99
+ #
100
+ # @return [Array] An array of filters (their 'internal_name's)
101
+ # ========================================================================= #
102
+ def list_filters
103
+ if @filters.empty?
104
+ fetch_configuration()
105
+ end
106
+ return @filters.keys
107
+ end
108
+
109
+ # ========================================================================= #
110
+ # === attributes
111
+ #
112
+ # Returns a hash (keyed by the biomart 'internal_name' for the attribute)
113
+ # of all of the Biomart::Attribute objects belonging to this dataset.
114
+ #
115
+ # @return [Hash] A hash of Biomart::Attribute objects keyed by 'internal_name'
116
+ # ========================================================================= #
117
+ def attributes
118
+ if @attributes.empty?
119
+ fetch_configuration()
120
+ end
121
+ return @attributes
122
+ end
123
+
124
+ # ========================================================================= #
125
+ # === list_attributes
126
+ #
127
+ # Returns an array of the attribute names (biomart 'internal_name')
128
+ # for this dataset.
129
+ #
130
+ # @return [Array] An array of attributes (their 'internal_name's)
131
+ # ========================================================================= #
132
+ def list_attributes
133
+ if @attributes.empty?
134
+ fetch_configuration
135
+ end
136
+ return @attributes.keys
137
+ end
138
+
139
+ # ========================================================================= #
140
+ # === count
141
+ #
142
+ # Function to perform a Biomart count. Returns an integer value for the
143
+ # result of the count query.
144
+ #
145
+ # arguments:
146
+ #
147
+ # {
148
+ # :timeout => integer, # set a timeout length for the request (secs) - optional
149
+ # :filters => {} # hash of key-value pairs (filter => search term) - optional
150
+ # }
151
+ #
152
+ # @param [Hash] args The arguments hash
153
+ # @raise Biomart::ArgumentError Raised when un-supported arguments are passed
154
+ # ========================================================================= #
155
+ def count(args = {})
156
+ if args[:federate]
157
+ raise Biomart::ArgumentError, 'You cannot federate a count query.'
158
+ end
159
+ if args[:required_attributes]
160
+ raise Biomart::ArgumentError,
161
+ 'The :required_attributes option is not allowed on count queries.'
162
+ end
163
+ result = request(
164
+ :method => 'post',
165
+ :url => @url,
166
+ :timeout => args[:timeout],
167
+ :query => generate_xml(
168
+ :filters => args[:filters],
169
+ :attributes => args[:attributes],
170
+ :count => "1"
171
+ )
172
+ )
173
+ return result.to_i
174
+ end
175
+
176
+ # ========================================================================= #
177
+ # === search
178
+ #
179
+ # Function to perform a Biomart search.
180
+ #
181
+ # optional arguments:
182
+ #
183
+ # {
184
+ # :process_results => true/false, # convert search results to object
185
+ # :timeout => integer, # set a timeout length for the request (secs)
186
+ # :filters => {}, # hash of key-value pairs (filter => search term)
187
+ # :attributes => [], # array of attributes to retrieve
188
+ # :required_attributes => [], # array of attributes that are required
189
+ # :federate => [
190
+ # {
191
+ # :dataset => Biomart::Dataset, # A dataset object to federate with
192
+ # :filters => {}, # hash of key-value pairs (filter => search term)
193
+ # :attributes => [] # array of attributes to retrieve
194
+ # }
195
+ # ]
196
+ # }
197
+ #
198
+ # Note, if you do not pass any filters or attributes arguments, the defaults
199
+ # for the dataset shall be used.
200
+ #
201
+ # Also, using the :required_attributes option - this performs AND logic and will require
202
+ # data to be returned in all of the listed attributes in order for it to be returned.
203
+ #
204
+ # By default will return a hash with the following:
205
+ #
206
+ # {
207
+ # :headers => [], # array of headers
208
+ # :data => [] # array of arrays containing search results
209
+ # }
210
+ #
211
+ # But with the :process_results option will return an array of hashes,
212
+ # where each hash represents a row of results (keyed by the attribute name).
213
+ #
214
+ # @param [Hash] args The arguments hash
215
+ # @return [Hash/Array] Will return a hash by default (of unprocessed
216
+ # data), or will return an array of hashes
217
+ # @raise Biomart::ArgumentError Raised if incorrect arguments are passed
218
+ #
219
+ # ========================================================================= #
220
+ def search(args = {})
221
+ if args[:required_attributes] and !args[:required_attributes].is_a?(Array)
222
+ raise Biomart::ArgumentError, "The :required_attributes option must be passed as an array."
223
+ end
224
+ response = request(
225
+ :method => 'post',
226
+ :url => @url,
227
+ :timeout => args[:timeout],
228
+ :query => generate_xml( process_xml_args(args) )
229
+ )
230
+ result = process_tsv(args, response)
231
+ result = filter_data_rows(args, result) if args[:required_attributes]
232
+ result = conv_results_to_a_of_h(result) if args[:process_results]
233
+ return result
234
+ end
235
+
236
+ # ========================================================================= #
237
+ # === generate_xml
238
+ #
239
+ # Utility function to build the Biomart query XML - used by #count and #search.
240
+ #
241
+ # @see #count
242
+ # @see #search
243
+ # ========================================================================= #
244
+ def generate_xml(
245
+ args = {}
246
+ )
247
+ biomart_xml = ''
248
+ xml = Builder::XmlMarkup.new( :target => biomart_xml, :indent => 2 )
249
+ xml.instruct!
250
+ xml.declare!( :DOCTYPE, :Query )
251
+ xml.Query( :virtualSchemaName => "default", :formatter => "TSV", :header => "0", :uniqueRows => "1", :count => args[:count], :datasetConfigVersion => "0.6" ) {
252
+ dataset_xml( xml, self, { :filters => args[:filters], :attributes => args[:attributes] } )
253
+ if args[:federate]
254
+ args[:federate].each { |joined_dataset|
255
+ unless joined_dataset[:dataset].is_a?(Biomart::Dataset)
256
+ raise Biomart::ArgumentError, "You must pass a Biomart::Dataset object to the :federate[:dataset] option."
257
+ end
258
+ dataset_xml(
259
+ xml,
260
+ joined_dataset[:dataset],
261
+ { :filters => joined_dataset[:filters], :attributes => joined_dataset[:attributes] }
262
+ )
263
+ }
264
+ end
265
+ }
266
+ return biomart_xml
267
+ end
268
+
269
+ # ========================================================================= #
270
+ # === alive?
271
+ #
272
+ # Simple heartbeat function to test that a Biomart server is online.
273
+ #
274
+ # @return [Boolean] true/false
275
+ # ========================================================================= #
276
+ def alive?
277
+ server = Biomart::Server.new(@url)
278
+ return server.alive?
279
+ end
280
+
281
+ # ========================================================================= #
282
+ # === name?
283
+ # ========================================================================= #
284
+ def name?
285
+ @name
286
+ end; alias name name? # === name
287
+
288
+ # ========================================================================= #
289
+ # === filter_data_rows
290
+ #
291
+ # Utility function to remove data rows from a search result that do not
292
+ # include the :required_attributes.
293
+ # ========================================================================= #
294
+ def filter_data_rows( args, result )
295
+ # ======================================================================= #
296
+ # Get the list of attributes searched for...
297
+ # ======================================================================= #
298
+ attributes = args[:attributes] ? args[:attributes] : []
299
+ if attributes.empty?
300
+ self.attributes.each { |name,attribute|
301
+ if attribute.default?
302
+ attributes.push(name)
303
+ end
304
+ }
305
+ end
306
+ # ======================================================================= #
307
+ # Work out which attribute positions we need to test.
308
+ # ======================================================================= #
309
+ positions_to_test = []
310
+ attributes.each_index { |index|
311
+ if args[:required_attributes].include?(attributes[index])
312
+ positions_to_test.push(index)
313
+ end
314
+ }
315
+ # ======================================================================= #
316
+ # Now go through the results and filter out the unwanted data.
317
+ # ======================================================================= #
318
+ filtered_data = []
319
+ result[:data].each { |data_row|
320
+ save_row_count = 0
321
+ positions_to_test.each { |position|
322
+ save_row_count = save_row_count + 1 unless data_row[position].nil?
323
+ }
324
+ if save_row_count == positions_to_test.size
325
+ filtered_data.push(data_row)
326
+ end
327
+ }
328
+ return {
329
+ :headers => result[:headers],
330
+ :data => filtered_data
331
+ }
332
+ end; private :filter_data_rows
333
+
334
+ private
335
+ # ======================================================================= #
336
+ # === fetch_configuration
337
+ #
338
+ # Utility function to retrieve and process the configuration
339
+ # xml for a dataset
340
+ # ======================================================================= #
341
+ def fetch_configuration
342
+ url = @url + "?type=configuration&dataset=#{@name}"
343
+ document = REXML::Document.new( request( :url => url ) )
344
+ # Filters...
345
+ ['//FilterDescription','//FilterDescription/Option'].each do |filter_xpath|
346
+ REXML::XPath.each( document, filter_xpath ) { |f|
347
+ if f.attributes['displayType'] != nil
348
+ next if f.attributes['displayType'] == 'container'
349
+ @filters[ f.attributes['internalName'] ] = Filter.new( f.attributes )
350
+ elsif f.attributes['pointerFilter'] != nil
351
+ pointer_filter = Filter.new( f.attributes )
352
+ @filters[ pointer_filter.name ] = pointer_filter
353
+ @filters[ pointer_filter.pointer_filter ] = pointer_filter
354
+ end
355
+ }
356
+ end
357
+ # Attributes are much simpler...
358
+ REXML::XPath.each( document, '//AttributeDescription' ) { |a|
359
+ @attributes[ a.attributes["internalName"] ] = Attribute.new( a.attributes )
360
+ }
361
+ end
362
+
363
+ # ======================================================================= #
364
+ # === process_xml_args
365
+ #
366
+ # Utility function to process and test the arguments passed for the
367
+ # xml query.
368
+ # ======================================================================= #
369
+ def process_xml_args( args = {} )
370
+ xml_args = {
371
+ filters: args[:filters],
372
+ attributes: args[:attributes]
373
+ }
374
+ if args[:federate]
375
+ unless args[:federate].is_a?(Array)
376
+ raise Biomart::ArgumentError,
377
+ 'The :federate option must be passed as an array.'
378
+ end
379
+ unless args[:federate].size == 1
380
+ raise Biomart::ArgumentError,
381
+ 'Sorry, we can only federate two datasets at present. '\
382
+ 'This limitation shall be lifted in version 0.8 of biomart.'
383
+ end
384
+ xml_args[:federate] = args[:federate]
385
+ end
386
+ return xml_args
387
+ end
388
+
389
+ # ======================================================================= #
390
+ # === dataset_xml
391
+ #
392
+ # Helper function to produce the portion of the biomart xml for
393
+ # a dataset query.
394
+ # ======================================================================= #
395
+ def dataset_xml( xml, dataset, args )
396
+ xml.Dataset( :name => dataset.name, :interface => "default" ) {
397
+ if args[:filters]
398
+ args[:filters].each { |name,value|
399
+ # =============================================================== #
400
+ # We must first check whether the specified filter exists
401
+ # or whether it does not.
402
+ # =============================================================== #
403
+ if dataset.filters[name].nil?
404
+ raise Biomart::ArgumentError, "The filter '#{name}' does not exist"
405
+ end
406
+ if dataset.filters[name].type == 'boolean'
407
+ value = value.downcase if value.is_a? String
408
+ if [true,'included','only'].include?(value)
409
+ xml.Filter( :name => name, :excluded => '0' )
410
+ elsif [false,'excluded'].include?(value)
411
+ xml.Filter( :name => name, :excluded => '1' )
412
+ else
413
+ raise Biomart::ArgumentError, "The boolean filter '#{name}' can only accept 'true/included/only' or 'false/excluded' arguments."
414
+ end
415
+ else
416
+ value = value.join(',') if value.is_a? Array
417
+ xml.Filter(
418
+ :name => name,
419
+ :value => value
420
+ )
421
+ end
422
+ }
423
+ else
424
+ dataset.filters.each { |name,filter|
425
+ if filter.default?
426
+ case filter.type
427
+ when 'boolean'
428
+ xml.Filter( :name => name, :excluded => filter.default_value )
429
+ else
430
+ xml.Filter( :name => name, :value => filter.default_value )
431
+ end
432
+ end
433
+ }
434
+ end
435
+ unless args[:count]
436
+ if args[:attributes]
437
+ args[:attributes].each { |name|
438
+ xml.Attribute( :name => name )
439
+ }
440
+ else
441
+ dataset.attributes.each { |name,attribute|
442
+ if attribute.default?
443
+ xml.Attribute( :name => name )
444
+ end
445
+ }
446
+ end
447
+ end
448
+ }
449
+ end
450
+
451
+ # ======================================================================= #
452
+ # === process_tsv
453
+ #
454
+ # Utility function to transform the tab-separated data retrieved
455
+ # from the Biomart search query into a ruby object.
456
+ # ======================================================================= #
457
+ def process_tsv( args, tsv )
458
+ headers = []
459
+ parsed_data = []
460
+ append_header_attributes_for_tsv( headers, self, args[:attributes] )
461
+ if args[:federate]
462
+ args[:federate].each { |joined_dataset|
463
+ append_header_attributes_for_tsv(
464
+ headers, joined_dataset[:dataset], joined_dataset[:attributes]
465
+ )
466
+ }
467
+ end
468
+ parsed_data = []
469
+ begin
470
+ parsed_data = CSV.parse( tsv, { :col_sep => "\t", :skip_blanks => true } )
471
+ rescue CSV::MalformedCSVError # Handle malformed .csv files.
472
+ parsed_data = parse_tsv_line_by_line( headers.size, tsv )
473
+ end
474
+ return {
475
+ :headers => headers,
476
+ :data => parsed_data
477
+ }
478
+ end
479
+
480
+ # ======================================================================= #
481
+ # === append_header_attributes_for_tsv
482
+ #
483
+ # Helper function to append the attribute names to the 'headers' array
484
+ # for processing the returned results.
485
+ # ======================================================================= #
486
+ def append_header_attributes_for_tsv(headers, dataset, attributes)
487
+ if attributes
488
+ attributes.each { |attribute|
489
+ headers.push(attribute)
490
+ }
491
+ else
492
+ dataset.attributes.each { |name,attribute|
493
+ if attribute.default?
494
+ headers.push(name)
495
+ end
496
+ }
497
+ end
498
+ end
499
+
500
+ # ======================================================================= #
501
+ # === parse_tsv_line_by_line
502
+ #
503
+ # Utility function to process TSV formatted data that raises errors.
504
+ # (Biomart has a habit of serving out this...)
505
+ #
506
+ # First attempts to use the CSV modules 'parse_line' function to read
507
+ # in the data, if that fails, tries to use split to recover the data.
508
+ # ======================================================================= #
509
+ def parse_tsv_line_by_line( expected_row_size, tsv )
510
+ parsed_data = []
511
+ data_by_line = tsv.split("\n")
512
+ data_by_line.each { |line|
513
+ elements = []
514
+ begin
515
+ elements = CSV.parse_line( line, { :col_sep => "\t" } ) || []
516
+ rescue CSV::MalformedCSVError # Handled malformed .csv files.
517
+ elements = []
518
+ end
519
+ if elements.size == 0
520
+ # ================================================================= #
521
+ # This is a bad line (causing the above Exception), try and
522
+ # use split to recover.
523
+ # ================================================================= #
524
+ elements = line.split("\t")
525
+ if line =~ /\t$/
526
+ # If the last attribute resturn is empty add a nil
527
+ # value to the array as it would have been missed
528
+ # by the split function!
529
+ elements.push(nil)
530
+ end
531
+ # Substitute blank strings for nils
532
+ elements.map! { |elem|
533
+ if elem.empty?
534
+ nil
535
+ else
536
+ elem
537
+ end
538
+ }
539
+ # ================================================================= #
540
+ # Add a safety clause.
541
+ # ================================================================= #
542
+ if elements.size === expected_row_size
543
+ parsed_data.push(elements)
544
+ end
545
+ else
546
+ parsed_data.push(elements)
547
+ end
548
+ }
549
+ return parsed_data
550
+ end
551
+
552
+ # ======================================================================= #
553
+ # === conv_results_to_a_of_h
554
+ #
555
+ # Utility function to quickly convert a search result into an array
556
+ # of Hashes (keyed by the attribute name) for easier processing -
557
+ # this is not done by default on all searches as this can cause a
558
+ # large overhead on big data returns.
559
+ # ======================================================================= #
560
+ def conv_results_to_a_of_h( search_results )
561
+ result_objects = []
562
+ search_results[:data].each { |row|
563
+ tmp = {}
564
+ row.each_index { |index|
565
+ tmp[ search_results[:headers][index] ] = row[index]
566
+ }
567
+ result_objects.push(tmp)
568
+ }
569
+ return result_objects
570
+ end
571
+
572
+ end; end; end