biointerchange 0.1.0 → 0.1.2

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (45) hide show
  1. data/.travis.yml +3 -3
  2. data/Gemfile +2 -1
  3. data/README.md +192 -7
  4. data/Rakefile +1 -1
  5. data/VERSION +1 -1
  6. data/examples/vocabulary.rb +23 -0
  7. data/generators/javaify.rb +131 -0
  8. data/generators/pythonify.rb +67 -0
  9. data/generators/rdfxml.rb +152 -44
  10. data/lib/biointerchange/core.rb +2 -1
  11. data/lib/biointerchange/exceptions.rb +27 -0
  12. data/lib/biointerchange/genomics/gff3_rdf_ntriples.rb +21 -18
  13. data/lib/biointerchange/gff3o.rb +495 -0
  14. data/lib/biointerchange/gvf1o.rb +730 -0
  15. data/lib/biointerchange/registry.rb +2 -2
  16. data/lib/biointerchange/sio.rb +10951 -5845
  17. data/lib/biointerchange/sofa.rb +2171 -1300
  18. data/spec/exceptions_spec.rb +6 -0
  19. data/spec/gff3_rdfwriter_spec.rb +7 -1
  20. data/spec/text_mining_pdfx_xml_reader_spec.rb +6 -0
  21. data/spec/text_mining_pubannos_json_reader_spec.rb +6 -0
  22. data/spec/text_mining_rdfwriter_spec.rb +6 -0
  23. data/supplemental/java/biointerchange/pom.xml +45 -0
  24. data/supplemental/java/biointerchange/src/main/java/org/biointerchange/App.java +58 -0
  25. data/supplemental/java/biointerchange/src/main/java/org/biointerchange/AppSIO.java +49 -0
  26. data/supplemental/java/biointerchange/src/main/java/org/biointerchange/vocabulary/GFF3O.java +647 -0
  27. data/supplemental/java/biointerchange/src/main/java/org/biointerchange/vocabulary/GVF1O.java +946 -0
  28. data/supplemental/java/biointerchange/src/main/java/org/biointerchange/vocabulary/SIO.java +15390 -0
  29. data/supplemental/java/biointerchange/src/main/java/org/biointerchange/vocabulary/SOFA.java +2968 -0
  30. data/supplemental/java/biointerchange/src/test/java/org/biointerchange/AppTest.java +38 -0
  31. data/supplemental/python/biointerchange/__init__.py +4 -0
  32. data/supplemental/python/biointerchange/gff3o.py +581 -0
  33. data/supplemental/python/biointerchange/gvf1o.py +864 -0
  34. data/supplemental/python/biointerchange/sio.py +11772 -0
  35. data/supplemental/python/biointerchange/sofa.py +2422 -0
  36. data/supplemental/python/example.py +19 -0
  37. data/supplemental/python/setup.py +13 -0
  38. data/web/about.html +3 -0
  39. data/web/api.html +219 -0
  40. data/web/index.html +4 -3
  41. data/web/ontologies.html +109 -0
  42. data/web/webservices.html +1 -0
  43. metadata +144 -117
  44. data/docs/exceptions_readme.txt +0 -13
  45. data/lib/biointerchange/gff3.rb +0 -135
@@ -2,1565 +2,2436 @@ module BioInterchange
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  class SOFA
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- def self.adjacent_to
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- RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:adjacent_to')
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+ def self.adjacent_to
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:adjacent_to')
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+ end
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+
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+ def self.complete_evidence_for_feature
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:complete_evidence_for_feature')
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+ end
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+
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+ def self.contained_by
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:contained_by')
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+ end
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+
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+ def self.contains
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:contains')
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+ end
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+
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+ def self.derives_from
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:derives_from')
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+ end
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+
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+ def self.evidence_for_feature
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:evidence_for_feature')
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+ end
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+
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+ def self.has_integral_part
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:has_integral_part')
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+ end
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+
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+ def self.has_part
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:has_part')
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+ end
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+
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+ def self.homologous_to
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:homologous_to')
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+ end
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+
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+ def self.integral_part_of
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:integral_part_of')
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+ end
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+
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+ def self.member_of
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:member_of')
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+ end
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+
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+ def self.non_functional_homolog_of
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:non_functional_homolog_of')
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+ end
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+
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+ def self.orthologous_to
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:orthologous_to')
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+ end
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+
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+ def self.paralogous_to
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:paralogous_to')
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+ end
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+
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+ def self.part_of
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:part_of')
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+ end
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+
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+ def self.partial_evidence_for_feature
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:partial_evidence_for_feature')
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+ end
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+
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+ def self.similar_to
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:similar_to')
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+ end
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+
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+ def self.Sequence_Ontology
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000000')
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+ end
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+
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+ # A sequence_feature with an extent greater than zero. A nucleotide region is composed of bases and a polypeptide region is composed of amino acids. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000001)
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+ def self.region
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000001')
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+ end
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+
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+ def self.interior_coding_exon
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000004')
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+ end
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+
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+ # The many tandem repeats (identical or related) of a short basic repeating unit; many have a base composition or other property different from the genome average that allows them to be separated from the bulk (main band) genomic DNA. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
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+ # (http://purl.obolibrary.org/obo/SO_0000005)
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+ def self.satellite_DNA
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000005')
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+ end
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+
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+ # A region amplified by a PCR reaction. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000006)
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+ def self.PCR_product
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000006')
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+ end
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+
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+ # One of a pair of sequencing reads in which the two members of the pair are related by originating at either end of a clone insert. (SO:ls)
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+ # (http://purl.obolibrary.org/obo/SO_0000007)
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+ def self.read_pair
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000007')
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+ end
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+
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+ # A small non coding RNA sequence, present in the cytoplasm. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000013)
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+ def self.scRNA
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000013')
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+ end
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+
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+ # A collection of match parts. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000038)
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+ def self.match_set
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000038')
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+ end
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+
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+ # A part of a match, for example an hsp from blast is a match_part. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000039)
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+ def self.match_part
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000039')
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+ end
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+
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+ # A part of a gene, that has no other route in the ontology back to region. This concept is necessary for logical inference as these parts must have the properties of region. It also allows us to associate all the parts of genes with a gene. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000050)
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+ def self.gene_part
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000050')
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+ end
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+
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+ # A regulatory element of an operon to which activators or repressors bind thereby effecting translation of genes in that operon. (SO:ma)
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+ # (http://purl.obolibrary.org/obo/SO_0000057)
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+ def self.operator
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000057')
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+ end
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+
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+ # A binding site that, of a nucleotide molecule, that interacts selectively and non-covalently with polypeptide residues of a nuclease. (SO:cb)
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+ # (http://purl.obolibrary.org/obo/SO_0000059)
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+ def self.nuclease_binding_site
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000059')
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+ end
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+
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+ # A transposon or insertion sequence. An element that can insert in a variety of DNA sequences. (http://www.sci.sdsu.edu/~smaloy/Glossary/T.html)
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+ # (http://purl.obolibrary.org/obo/SO_0000101)
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+ def self.transposable_element
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000101')
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+ end
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+
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+ # A match to an EST or cDNA sequence. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000102)
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+ def self.expressed_sequence_match
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000102')
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+ end
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+
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+ # The end of the clone insert. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000103)
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+ def self.clone_insert_end
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000103')
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+ end
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+
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+ # A sequence of amino acids linked by peptide bonds which may lack appreciable tertiary structure and may not be liable to irreversible denaturation. (SO:ma)
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+ # (http://purl.obolibrary.org/obo/SO_0000104)
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+ def self.polypeptide
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000104')
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+ end
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+
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+ # A sequence_variant is a non exact copy of a sequence_feature or genome exhibiting one or more sequence_alteration. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000109)
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+ def self.sequence_variant_obs
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000109')
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+ end
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+
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+ # An extent of biological sequence. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000110)
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+ def self.sequence_feature
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000110')
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+ end
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+
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+ # An oligo to which new deoxyribonucleotides can be added by DNA polymerase. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000112)
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+ def self.primer
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000112')
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+ end
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+
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+ # A viral sequence which has integrated into a host genome. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000113)
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+ def self.proviral_region
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000113')
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+ end
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+
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+ # A methylated deoxy-cytosine. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000114)
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+ def self.methylated_C
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000114')
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+ end
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+
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+ # A primary transcript that, at least in part, encodes one or more proteins. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000120)
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+ def self.protein_coding_primary_transcript
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000120')
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+ end
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+
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+ # Region in mRNA where ribosome assembles. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000139)
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+ def self.ribosome_entry_site
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000139')
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+ end
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+
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+ # A sequence segment located within the five prime end of an mRNA that causes premature termination of translation. (SO:as)
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+ # (http://purl.obolibrary.org/obo/SO_0000140)
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+ def self.attenuator
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000140')
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+ end
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+
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+ # The sequence of DNA located either at the end of the transcript that causes RNA polymerase to terminate transcription. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
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+ # (http://purl.obolibrary.org/obo/SO_0000141)
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+ def self.terminator
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000141')
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+ end
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+
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+ # A region of known length which may be used to manufacture a longer region. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000143)
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+ def self.assembly_component
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000143')
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+ end
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+
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+ # A region of the transcript sequence within a gene which is not removed from the primary RNA transcript by RNA splicing. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000147)
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+ def self.exon
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000147')
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+ end
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+
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+ # One or more contigs that have been ordered and oriented using end-read information. Contains gaps that are filled with N's. (SO:ls)
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+ # (http://purl.obolibrary.org/obo/SO_0000148)
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+ def self.supercontig
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000148')
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+ end
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+
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+ # A contiguous sequence derived from sequence assembly. Has no gaps, but may contain N's from unavailable bases. (SO:ls)
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+ # (http://purl.obolibrary.org/obo/SO_0000149)
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+ def self.contig
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000149')
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+ end
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+
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+ # A sequence obtained from a single sequencing experiment. Typically a read is produced when a base calling program interprets information from a chromatogram trace file produced from a sequencing machine. (SO:rd)
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+ # (http://purl.obolibrary.org/obo/SO_0000150)
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+ def self.read
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000150')
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+ end
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+
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+ # A piece of DNA that has been inserted in a vector so that it can be propagated in a host bacterium or some other organism. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000151)
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+ def self.clone
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000151')
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+ end
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+
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+ # The point at which one or more contiguous nucleotides were excised. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000159)
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+ def self.deletion
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000159')
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+ end
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+
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+ # A modified RNA base in which adenine has been methylated. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000161)
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+ def self.methylated_A
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000161')
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+ end
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+
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+ # Consensus region of primary transcript bordering junction of splicing. A region that overlaps exactly 2 base and adjacent_to splice_junction. (SO:cjm, SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000162)
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+ def self.splice_site
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000162')
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+ end
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+
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+ # Intronic 2 bp region bordering the exon, at the 5' edge of the intron. A splice_site that is downstream_adjacent_to exon and starts intron. (http://www.ucl.ac.uk/~ucbhjow/b241/glossary.html, SO:cjm, SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000163)
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+ def self.five_prime_cis_splice_site
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000163')
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+ end
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+
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+ # Intronic 2 bp region bordering the exon, at the 3' edge of the intron. A splice_site that is upstream_adjacent_to exon and finishes intron. (http://www.ucl.ac.uk/~ucbhjow/b241/glossary.html, SO:cjm, SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000164)
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+ def self.three_prime_cis_splice_site
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000164')
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+ end
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+
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+ # A cis-acting sequence that increases the utilization of (some) eukaryotic promoters, and can function in either orientation and in any location (upstream or downstream) relative to the promoter. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
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+ # (http://purl.obolibrary.org/obo/SO_0000165)
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+ def self.enhancer
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000165')
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+ end
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+
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+ # A regulatory_region composed of the TSS(s) and binding sites for TF_complexes of the basal transcription machinery. (SO:regcreative)
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+ # (http://purl.obolibrary.org/obo/SO_0000167)
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+ def self.promoter
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000167')
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+ end
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+
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+ # A nucleotide match against a sequence from another organism. (SO:ma)
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+ # (http://purl.obolibrary.org/obo/SO_0000177)
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+ def self.cross_genome_match
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000177')
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+ end
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+
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+ # A group of contiguous genes transcribed as a single (polycistronic) mRNA from a single regulatory region. (SO:ma)
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+ # (http://purl.obolibrary.org/obo/SO_0000178)
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+ def self.operon
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000178')
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+ end
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+
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+ # The start of the clone insert. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000179)
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+ def self.clone_insert_start
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000179')
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+ end
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+
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+ # A match against a translated sequence. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000181)
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+ def self.translated_nucleotide_match
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000181')
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+ end
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+
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+ # A region of the gene which is not transcribed. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000183)
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+ def self.non_transcribed_region
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000183')
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+ end
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+
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+ # A transcript that in its initial state requires modification to be functional. (SO:ma)
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+ # (http://purl.obolibrary.org/obo/SO_0000185)
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+ def self.primary_transcript
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000185')
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+ end
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+
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+ # A group of characterized repeat sequences. (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000187)
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+ def self.repeat_family
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000187')
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+ end
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+
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+ # A region of a primary transcript that is transcribed, but removed from within the transcript by splicing together the sequences (exons) on either side of it. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
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+ # (http://purl.obolibrary.org/obo/SO_0000188)
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+ def self.intron
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000188')
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+ end
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+
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+ # A DNA fragment used as a reagent to detect the polymorphic genomic loci by hybridizing against the genomic DNA digested with a given restriction enzyme. (GOC:pj)
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+ # (http://purl.obolibrary.org/obo/SO_0000193)
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+ def self.RFLP_fragment
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000193')
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+ end
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+
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+ # An exon whereby at least one base is part of a codon (here, 'codon' is inclusive of the stop_codon). (SO:ke)
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+ # (http://purl.obolibrary.org/obo/SO_0000195)
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+ def self.coding_exon
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000195')
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+ end
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+
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+ # The sequence of the five_prime_coding_exon that codes for protein. (SO:cjm)
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+ # (http://purl.obolibrary.org/obo/SO_0000196)
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+ def self.five_prime_coding_exon_coding_region
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+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000196')
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+ end
362
+
363
+ # The sequence of the three_prime_coding_exon that codes for protein. (SO:cjm)
364
+ # (http://purl.obolibrary.org/obo/SO_0000197)
365
+ def self.three_prime_coding_exon_coding_region
366
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000197')
367
+ end
368
+
369
+ # An exon that does not contain any codons. (SO:ke)
370
+ # (http://purl.obolibrary.org/obo/SO_0000198)
371
+ def self.noncoding_exon
372
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000198')
373
+ end
374
+
375
+ # The 5' most coding exon. (SO:ke)
376
+ # (http://purl.obolibrary.org/obo/SO_0000200)
377
+ def self.five_prime_coding_exon
378
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000200')
379
+ end
380
+
381
+ # Messenger RNA sequences that are untranslated and lie five prime or three prime to sequences which are translated. (SO:ke)
382
+ # (http://purl.obolibrary.org/obo/SO_0000203)
383
+ def self.UTR
384
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000203')
385
+ end
386
+
387
+ # A region at the 5' end of a mature transcript (preceding the initiation codon) that is not translated into a protein. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
388
+ # (http://purl.obolibrary.org/obo/SO_0000204)
389
+ def self.five_prime_UTR
390
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000204')
391
+ end
392
+
393
+ # A region at the 3' end of a mature transcript (following the stop codon) that is not translated into a protein. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
394
+ # (http://purl.obolibrary.org/obo/SO_0000205)
395
+ def self.three_prime_UTR
396
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000205')
397
+ end
398
+
399
+ # A primary transcript encoding a ribosomal RNA. (SO:ke)
400
+ # (http://purl.obolibrary.org/obo/SO_0000209)
401
+ def self.rRNA_primary_transcript
402
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000209')
403
+ end
404
+
405
+ # A transcript which has undergone the necessary modifications, if any, for its function. In eukaryotes this includes, for example, processing of introns, cleavage, base modification, and modifications to the 5' and/or the 3' ends, other than addition of bases. In bacteria functional mRNAs are usually not modified. (SO:ke)
406
+ # (http://purl.obolibrary.org/obo/SO_0000233)
407
+ def self.mature_transcript
408
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000233')
409
+ end
410
+
411
+ # Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns. (SO:ma)
412
+ # (http://purl.obolibrary.org/obo/SO_0000234)
413
+ def self.mRNA
414
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000234')
415
+ end
416
+
417
+ # A region of a nucleotide molecule that binds a Transcription Factor or Transcription Factor complex [GO:0005667]. (SO:ke)
418
+ # (http://purl.obolibrary.org/obo/SO_0000235)
419
+ def self.TF_binding_site
420
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000235')
421
+ end
422
+
423
+ # The in-frame interval between the stop codons of a reading frame which when read as sequential triplets, has the potential of encoding a sequential string of amino acids. TER(NNN)nTER. (SGD:rb, SO:ma)
424
+ # (http://purl.obolibrary.org/obo/SO_0000236)
425
+ def self.ORF
426
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000236')
427
+ end
428
+
429
+ # The sequences extending on either side of a specific region. (SO:ke)
430
+ # (http://purl.obolibrary.org/obo/SO_0000239)
431
+ def self.flanking_region
432
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000239')
433
+ end
434
+
435
+ # RNA that comprises part of a ribosome, and that can provide both structural scaffolding and catalytic activity. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html, ISBN:0198506732)
436
+ # (http://purl.obolibrary.org/obo/SO_0000252)
437
+ def self.rRNA
438
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000252')
439
+ end
440
+
441
+ # Transfer RNA (tRNA) molecules are approximately 80 nucleotides in length. Their secondary structure includes four short double-helical elements and three loops (D, anti-codon, and T loops). Further hydrogen bonds mediate the characteristic L-shaped molecular structure. Transfer RNAs have two regions of fundamental functional importance: the anti-codon, which is responsible for specific mRNA codon recognition, and the 3' end, to which the tRNA's corresponding amino acid is attached (by aminoacyl-tRNA synthetases). Transfer RNAs cope with the degeneracy of the genetic code in two manners: having more than one tRNA (with a specific anti-codon) for a particular amino acid; and 'wobble' base-pairing, i.e. permitting non-standard base-pairing at the 3rd anti-codon position. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00005, ISBN:0198506732)
442
+ # (http://purl.obolibrary.org/obo/SO_0000253)
443
+ def self.tRNA
444
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000253')
445
+ end
446
+
447
+ # A small nuclear RNA molecule involved in pre-mRNA splicing and processing. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html, PMID:11733745, WB:ems)
448
+ # (http://purl.obolibrary.org/obo/SO_0000274)
449
+ def self.snRNA
450
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000274')
451
+ end
452
+
453
+ # A snoRNA (small nucleolar RNA) is any one of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing or modifications of many RNAs, mostly ribosomal RNAs (rRNAs) though snoRNAs are also known to target other classes of RNA, including spliceosomal RNAs, tRNAs, and mRNAs via a stretch of sequence that is complementary to a sequence in the targeted RNA. (GOC:kgc)
454
+ # (http://purl.obolibrary.org/obo/SO_0000275)
455
+ def self.snoRNA
456
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000275')
457
+ end
458
+
459
+ # Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors. (PMID:12592000)
460
+ # (http://purl.obolibrary.org/obo/SO_0000276)
461
+ def self.miRNA
462
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000276')
463
+ end
464
+
465
+ # A repeat_region containing repeat_units (2 to 4 bp) that is repeated multiple times in tandem. (http://www.informatics.jax.org/silver/glossary.shtml)
466
+ # (http://purl.obolibrary.org/obo/SO_0000289)
467
+ def self.microsatellite
468
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000289')
469
+ end
470
+
471
+ # The sequence is complementarily repeated on the opposite strand. It is a palindrome, and it may, or may not be hyphenated. Examples: GCTGATCAGC, or GCTGA-----TCAGC. (SO:ke)
472
+ # (http://purl.obolibrary.org/obo/SO_0000294)
473
+ def self.inverted_repeat
474
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000294')
475
+ end
476
+
477
+ # The origin of replication; starting site for duplication of a nucleic acid molecule to give two identical copies. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
478
+ # (http://purl.obolibrary.org/obo/SO_0000296)
479
+ def self.origin_of_replication
480
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000296')
481
+ end
482
+
483
+ # Part of the primary transcript that is clipped off during processing. (SO:ke)
484
+ # (http://purl.obolibrary.org/obo/SO_0000303)
485
+ def self.clip
486
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000303')
487
+ end
488
+
489
+ # A modified nucleotide, i.e. a nucleotide other than A, T, C. G. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
490
+ # (http://purl.obolibrary.org/obo/SO_0000305)
491
+ def self.modified_base
492
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000305')
493
+ end
494
+
495
+ # A nucleotide modified by methylation. (SO:ke)
496
+ # (http://purl.obolibrary.org/obo/SO_0000306)
497
+ def self.methylated_base_feature
498
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000306')
499
+ end
500
+
501
+ # Regions of a few hundred to a few thousand bases in vertebrate genomes that are relatively GC and CpG rich; they are typically unmethylated and often found near the 5' ends of genes. (SO:rd)
502
+ # (http://purl.obolibrary.org/obo/SO_0000307)
503
+ def self.CpG_island
504
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000307')
505
+ end
506
+
507
+ # A repeat where the same sequence is repeated in the same direction. Example: GCTGA-----GCTGA. (SO:ke)
508
+ # (http://purl.obolibrary.org/obo/SO_0000314)
509
+ def self.direct_repeat
510
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000314')
511
+ end
512
+
513
+ # The first base where RNA polymerase begins to synthesize the RNA transcript. (SO:ke)
514
+ # (http://purl.obolibrary.org/obo/SO_0000315)
515
+ def self.TSS
516
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000315')
517
+ end
518
+
519
+ # A contiguous sequence which begins with, and includes, a start codon and ends with, and includes, a stop codon. (SO:ma)
520
+ # (http://purl.obolibrary.org/obo/SO_0000316)
521
+ def self.CDS
522
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000316')
523
+ end
524
+
525
+ # First codon to be translated by a ribosome. (SO:ke)
526
+ # (http://purl.obolibrary.org/obo/SO_0000318)
527
+ def self.start_codon
528
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000318')
529
+ end
530
+
531
+ # In mRNA, a set of three nucleotides that indicates the end of information for protein synthesis. (SO:ke)
532
+ # (http://purl.obolibrary.org/obo/SO_0000319)
533
+ def self.stop_codon
534
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000319')
535
+ end
536
+
537
+ # A nucleotide sequence that may be used to identify a larger sequence. (SO:ke)
538
+ # (http://purl.obolibrary.org/obo/SO_0000324)
539
+ def self.tag
540
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000324')
541
+ end
542
+
543
+ # A primary transcript encoding a large ribosomal subunit RNA. (SO:ke)
544
+ # (http://purl.obolibrary.org/obo/SO_0000325)
545
+ def self.rRNA_large_subunit_primary_transcript
546
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000325')
547
+ end
548
+
549
+ # A short diagnostic sequence tag, serial analysis of gene expression (SAGE), that allows the quantitative and simultaneous analysis of a large number of transcripts. (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7570003&dopt=Abstract)
550
+ # (http://purl.obolibrary.org/obo/SO_0000326)
551
+ def self.SAGE_tag
552
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000326')
553
+ end
554
+
555
+ # Region of sequence similarity by descent from a common ancestor. (SO:ke)
556
+ # (http://purl.obolibrary.org/obo/SO_0000330)
557
+ def self.conserved_region
558
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000330')
559
+ end
560
+
561
+ # Short (typically a few hundred base pairs) DNA sequence that has a single occurrence in a genome and whose location and base sequence are known. (http://www.biospace.com)
562
+ # (http://purl.obolibrary.org/obo/SO_0000331)
563
+ def self.STS
564
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000331')
565
+ end
566
+
567
+ # Coding region of sequence similarity by descent from a common ancestor. (SO:ke)
568
+ # (http://purl.obolibrary.org/obo/SO_0000332)
569
+ def self.coding_conserved_region
570
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000332')
571
+ end
572
+
573
+ # The boundary between two exons in a processed transcript. (SO:ke)
574
+ # (http://purl.obolibrary.org/obo/SO_0000333)
575
+ def self.exon_junction
576
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000333')
577
+ end
578
+
579
+ # Non-coding region of sequence similarity by descent from a common ancestor. (SO:ke)
580
+ # (http://purl.obolibrary.org/obo/SO_0000334)
581
+ def self.nc_conserved_region
582
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000334')
583
+ end
584
+
585
+ # A sequence that closely resembles a known functional gene, at another locus within a genome, that is non-functional as a consequence of (usually several) mutations that prevent either its transcription or translation (or both). In general, pseudogenes result from either reverse transcription of a transcript of their \"normal\" paralog (SO:0000043) (in which case the pseudogene typically lacks introns and includes a poly(A) tail) or from recombination (SO:0000044) (in which case the pseudogene is typically a tandem duplication of its \"normal\" paralog). (http://www.ucl.ac.uk/~ucbhjow/b241/glossary.html)
586
+ # (http://purl.obolibrary.org/obo/SO_0000336)
587
+ def self.pseudogene
588
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000336')
589
+ end
590
+
591
+ # A double stranded RNA duplex, at least 20bp long, used experimentally to inhibit gene function by RNA interference. (SO:rd)
592
+ # (http://purl.obolibrary.org/obo/SO_0000337)
593
+ def self.RNAi_reagent
594
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000337')
595
+ end
596
+
597
+ # Structural unit composed of a nucleic acid molecule which controls its own replication through the interaction of specific proteins at one or more origins of replication. (SO:ma)
598
+ # (http://purl.obolibrary.org/obo/SO_0000340)
599
+ def self.chromosome
600
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000340')
601
+ end
602
+
603
+ # A cytologically distinguishable feature of a chromosome, often made visible by staining, and usually alternating light and dark. (SO:ma)
604
+ # (http://purl.obolibrary.org/obo/SO_0000341)
605
+ def self.chromosome_band
606
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000341')
607
+ end
608
+
609
+ # A region of sequence, aligned to another sequence with some statistical significance, using an algorithm such as BLAST or SIM4. (SO:ke)
610
+ # (http://purl.obolibrary.org/obo/SO_0000343)
611
+ def self.match
612
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000343')
613
+ end
614
+
615
+ # Region of a transcript that regulates splicing. (SO:ke)
616
+ # (http://purl.obolibrary.org/obo/SO_0000344)
617
+ def self.splice_enhancer
618
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000344')
619
+ end
620
+
621
+ # A tag produced from a single sequencing read from a cDNA clone or PCR product; typically a few hundred base pairs long. (SO:ke)
622
+ # (http://purl.obolibrary.org/obo/SO_0000345)
623
+ def self.EST
624
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000345')
625
+ end
626
+
627
+ # A match against a nucleotide sequence. (SO:ke)
628
+ # (http://purl.obolibrary.org/obo/SO_0000347)
629
+ def self.nucleotide_match
630
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000347')
631
+ end
632
+
633
+ # A match against a protein sequence. (SO:ke)
634
+ # (http://purl.obolibrary.org/obo/SO_0000349)
635
+ def self.protein_match
636
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000349')
637
+ end
638
+
639
+ # A sequence of nucleotides that has been algorithmically derived from an alignment of two or more different sequences. (SO:ma)
640
+ # (http://purl.obolibrary.org/obo/SO_0000353)
641
+ def self.sequence_assembly
642
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000353')
643
+ end
644
+
645
+ # A set of (usually) three nucleotide bases in a DNA or RNA sequence, which together code for a unique amino acid or the termination of translation and are contained within the CDS. (http://www.everythingbio.com/glos/definition.php?word=codon, SO:ke)
646
+ # (http://purl.obolibrary.org/obo/SO_0000360)
647
+ def self.codon
648
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000360')
649
+ end
650
+
651
+ # The junction where an insertion occurred. (SO:ke)
652
+ # (http://purl.obolibrary.org/obo/SO_0000366)
653
+ def self.insertion_site
654
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000366')
655
+ end
656
+
657
+ # The junction in a genome where a transposable_element has inserted. (SO:ke)
658
+ # (http://purl.obolibrary.org/obo/SO_0000368)
659
+ def self.transposable_element_insertion_site
660
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000368')
661
+ end
662
+
663
+ # A non-coding RNA, usually with a specific secondary structure, that acts to regulate gene expression. (SO:ma)
664
+ # (http://purl.obolibrary.org/obo/SO_0000370)
665
+ def self.small_regulatory_ncRNA
666
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000370')
667
+ end
668
+
669
+ # An RNA sequence that has catalytic activity with or without an associated ribonucleoprotein. (RSC:cb)
670
+ # (http://purl.obolibrary.org/obo/SO_0000372)
671
+ def self.enzymatic_RNA
672
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000372')
673
+ end
674
+
675
+ # An RNA with catalytic activity. (SO:ma)
676
+ # (http://purl.obolibrary.org/obo/SO_0000374)
677
+ def self.ribozyme
678
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000374')
679
+ end
680
+
681
+ # 5_8S ribosomal RNA (5. 8S rRNA) is a component of the large subunit of the eukaryotic ribosome. It is transcribed by RNA polymerase I as part of the 45S precursor that also contains 18S and 28S rRNA. Functionally, it is thought that 5.8S rRNA may be involved in ribosome translocation. It is also known to form covalent linkage to the p53 tumour suppressor protein. 5_8S rRNA is also found in archaea. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00002)
682
+ # (http://purl.obolibrary.org/obo/SO_0000375)
683
+ def self.rRNA_5_8S
684
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000375')
685
+ end
686
+
687
+ # A small catalytic RNA motif that catalyzes self-cleavage reaction. Its name comes from its secondary structure which resembles a carpenter's hammer. The hammerhead ribozyme is involved in the replication of some viroid and some satellite RNAs. (PMID:2436805)
688
+ # (http://purl.obolibrary.org/obo/SO_0000380)
689
+ def self.hammerhead_ribozyme
690
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000380')
691
+ end
692
+
693
+ # The RNA molecule essential for the catalytic activity of RNase MRP, an enzymatically active ribonucleoprotein with two distinct roles in eukaryotes. In mitochondria it plays a direct role in the initiation of mitochondrial DNA replication. In the nucleus it is involved in precursor rRNA processing, where it cleaves the internal transcribed spacer 1 between 18S and 5.8S rRNAs. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00030)
694
+ # (http://purl.obolibrary.org/obo/SO_0000385)
695
+ def self.RNase_MRP_RNA
696
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000385')
697
+ end
698
+
699
+ # The RNA component of Ribonuclease P (RNase P), a ubiquitous endoribonuclease, found in archaea, bacteria and eukarya as well as chloroplasts and mitochondria. Its best characterized activity is the generation of mature 5 prime ends of tRNAs by cleaving the 5 prime leader elements of precursor-tRNAs. Cellular RNase Ps are ribonucleoproteins. RNA from bacterial RNase Ps retains its catalytic activity in the absence of the protein subunit, i.e. it is a ribozyme. Isolated eukaryotic and archaeal RNase P RNA has not been shown to retain its catalytic function, but is still essential for the catalytic activity of the holoenzyme. Although the archaeal and eukaryotic holoenzymes have a much greater protein content than the bacterial ones, the RNA cores from all the three lineages are homologous. Helices corresponding to P1, P2, P3, P4, and P10/11 are common to all cellular RNase P RNAs. Yet, there is considerable sequence variation, particularly among the eukaryotic RNAs. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00010)
700
+ # (http://purl.obolibrary.org/obo/SO_0000386)
701
+ def self.RNase_P_RNA
702
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000386')
703
+ end
704
+
705
+ # The RNA component of telomerase, a reverse transcriptase that synthesizes telomeric DNA. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00025)
706
+ # (http://purl.obolibrary.org/obo/SO_0000390)
707
+ def self.telomerase_RNA
708
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000390')
709
+ end
710
+
711
+ # U1 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Its 5' end forms complementary base pairs with the 5' splice junction, thus defining the 5' donor site of an intron. There are significant differences in sequence and secondary structure between metazoan and yeast U1 snRNAs, the latter being much longer (568 nucleotides as compared to 164 nucleotides in human). Nevertheless, secondary structure predictions suggest that all U1 snRNAs share a 'common core' consisting of helices I, II, the proximal region of III, and IV. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00003)
712
+ # (http://purl.obolibrary.org/obo/SO_0000391)
713
+ def self.U1_snRNA
714
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000391')
715
+ end
716
+
717
+ # U2 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Complementary binding between U2 snRNA (in an area lying towards the 5' end but 3' to hairpin I) and the branchpoint sequence (BPS) of the intron results in the bulging out of an unpaired adenine, on the BPS, which initiates a nucleophilic attack at the intronic 5' splice site, thus starting the first of two transesterification reactions that mediate splicing. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00004)
718
+ # (http://purl.obolibrary.org/obo/SO_0000392)
719
+ def self.U2_snRNA
720
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000392')
721
+ end
722
+
723
+ # U4 small nuclear RNA (U4 snRNA) is a component of the major U2-dependent spliceosome. It forms a duplex with U6, and with each splicing round, it is displaced from U6 (and the spliceosome) in an ATP-dependent manner, allowing U6 to refold and create the active site for splicing catalysis. A recycling process involving protein Prp24 re-anneals U4 and U6. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00015)
724
+ # (http://purl.obolibrary.org/obo/SO_0000393)
725
+ def self.U4_snRNA
726
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000393')
727
+ end
728
+
729
+ # An snRNA required for the splicing of the minor U12-dependent class of eukaryotic nuclear introns. It forms a base paired complex with U6atac_snRNA (SO:0000397). (PMID:=12409455)
730
+ # (http://purl.obolibrary.org/obo/SO_0000394)
731
+ def self.U4atac_snRNA
732
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000394')
733
+ end
734
+
735
+ # U5 RNA is a component of both types of known spliceosome. The precise function of this molecule is unknown, though it is known that the 5' loop is required for splice site selection and p220 binding, and that both the 3' stem-loop and the Sm site are important for Sm protein binding and cap methylation. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00020)
736
+ # (http://purl.obolibrary.org/obo/SO_0000395)
737
+ def self.U5_snRNA
738
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000395')
739
+ end
740
+
741
+ # U6 snRNA is a component of the spliceosome which is involved in splicing pre-mRNA. The putative secondary structure consensus base pairing is confined to a short 5' stem loop, but U6 snRNA is thought to form extensive base-pair interactions with U4 snRNA. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00015)
742
+ # (http://purl.obolibrary.org/obo/SO_0000396)
743
+ def self.U6_snRNA
744
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000396')
745
+ end
746
+
747
+ # U6atac_snRNA is an snRNA required for the splicing of the minor U12-dependent class of eukaryotic nuclear introns. It forms a base paired complex with U4atac_snRNA (SO:0000394). (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=retrieve&db=pubmed&list_uids=12409455&dopt=Abstract)
748
+ # (http://purl.obolibrary.org/obo/SO_0000397)
749
+ def self.U6atac_snRNA
750
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000397')
751
+ end
752
+
753
+ # U11 snRNA plays a role in splicing of the minor U12-dependent class of eukaryotic nuclear introns, similar to U1 snRNA in the major class spliceosome it base pairs to the conserved 5' splice site sequence. (PMID:9622129)
754
+ # (http://purl.obolibrary.org/obo/SO_0000398)
755
+ def self.U11_snRNA
756
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000398')
757
+ end
758
+
759
+ # The U12 small nuclear (snRNA), together with U4atac/U6atac, U5, and U11 snRNAs and associated proteins, forms a spliceosome that cleaves a divergent class of low-abundance pre-mRNA introns. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00007)
760
+ # (http://purl.obolibrary.org/obo/SO_0000399)
761
+ def self.U12_snRNA
762
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000399')
763
+ end
764
+
765
+ # U14 small nucleolar RNA (U14 snoRNA) is required for early cleavages of eukaryotic precursor rRNAs. In yeasts, this molecule possess a stem-loop region (known as the Y-domain) which is essential for function. A similar structure, but with a different consensus sequence, is found in plants, but is absent in vertebrates. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00016, PMID:2551119)
766
+ # (http://purl.obolibrary.org/obo/SO_0000403)
767
+ def self.U14_snoRNA
768
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000403')
769
+ end
770
+
771
+ # A family of RNAs are found as part of the enigmatic vault ribonucleoprotein complex. The complex consists of a major vault protein (MVP), two minor vault proteins (VPARP and TEP1), and several small untranslated RNA molecules. It has been suggested that the vault complex is involved in drug resistance. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00006)
772
+ # (http://purl.obolibrary.org/obo/SO_0000404)
773
+ def self.vault_RNA
774
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000404')
775
+ end
776
+
777
+ # Y RNAs are components of the Ro ribonucleoprotein particle (Ro RNP), in association with Ro60 and La proteins. The Y RNAs and Ro60 and La proteins are well conserved, but the function of the Ro RNP is not known. In humans the RNA component can be one of four small RNAs: hY1, hY3, hY4 and hY5. These small RNAs are predicted to fold into a conserved secondary structure containing three stem structures. The largest of the four, hY1, contains an additional hairpin. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00019)
778
+ # (http://purl.obolibrary.org/obo/SO_0000405)
779
+ def self.Y_RNA
780
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000405')
781
+ end
782
+
783
+ # A large polynucleotide in eukaryotes, which functions as the small subunit of the ribosome. (SO:ke)
784
+ # (http://purl.obolibrary.org/obo/SO_0000407)
785
+ def self.rRNA_18S
786
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000407')
787
+ end
788
+
789
+ # A biological_region of sequence that, in the molecule, interacts selectively and non-covalently with other molecules. A region on the surface of a molecule that may interact with another molecule. When applied to polypeptides: Amino acids involved in binding or interactions. It can also apply to an amino acid bond which is represented by the positions of the two flanking amino acids. (EBIBS:GAR, SO:ke)
790
+ # (http://purl.obolibrary.org/obo/SO_0000409)
791
+ def self.binding_site
792
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000409')
793
+ end
794
+
795
+ # A binding site that, in the molecule, interacts selectively and non-covalently with polypeptide molecules. (SO:ke)
796
+ # (http://purl.obolibrary.org/obo/SO_0000410)
797
+ def self.protein_binding_site
798
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000410')
799
+ end
800
+
801
+ # A region of polynucleotide sequence produced by digestion with a restriction endonuclease. (SO:ke)
802
+ # (http://purl.obolibrary.org/obo/SO_0000412)
803
+ def self.restriction_fragment
804
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000412')
805
+ end
806
+
807
+ # A region where the sequence differs from that of a specified sequence. (SO:ke)
808
+ # (http://purl.obolibrary.org/obo/SO_0000413)
809
+ def self.sequence_difference
810
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000413')
811
+ end
812
+
813
+ # The signal_peptide is a short region of the peptide located at the N-terminus that directs the protein to be secreted or part of membrane components. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
814
+ # (http://purl.obolibrary.org/obo/SO_0000418)
815
+ def self.signal_peptide
816
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000418')
817
+ end
818
+
819
+ # The polypeptide sequence that remains when the cleaved peptide regions have been cleaved from the immature peptide. (EBIBS:GAR, http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html, SO:cb)
820
+ # (http://purl.obolibrary.org/obo/SO_0000419)
821
+ def self.mature_protein_region
822
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000419')
823
+ end
824
+
825
+ # A sequence that can autonomously replicate, as a plasmid, when transformed into a bacterial host. (SO:ma)
826
+ # (http://purl.obolibrary.org/obo/SO_0000436)
827
+ def self.ARS
828
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000436')
829
+ end
830
+
831
+ # A single stranded oligonucleotide. (SO:ke)
832
+ # (http://purl.obolibrary.org/obo/SO_0000441)
833
+ def self.ss_oligo
834
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000441')
835
+ end
836
+
837
+ # A double stranded oligonucleotide. (SO:ke)
838
+ # (http://purl.obolibrary.org/obo/SO_0000442)
839
+ def self.ds_oligo
840
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000442')
841
+ end
842
+
843
+ # A 17-28-nt, small interfering RNA derived from transcripts of repetitive elements. (http://www.developmentalcell.com/content/article/abstract?uid=PIIS1534580703002284)
844
+ # (http://purl.obolibrary.org/obo/SO_0000454)
845
+ def self.rasiRNA
846
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000454')
847
+ end
848
+
849
+ # A non-functional descendent of a functional entity. (SO:cjm)
850
+ # (http://purl.obolibrary.org/obo/SO_0000462)
851
+ def self.pseudogenic_region
852
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000462')
853
+ end
854
+
855
+ # A non-functional descendant of an exon. (SO:ke)
856
+ # (http://purl.obolibrary.org/obo/SO_0000464)
857
+ def self.decayed_exon
858
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000464')
859
+ end
860
+
861
+ # One of the pieces of sequence that make up a golden path. (SO:rd)
862
+ # (http://purl.obolibrary.org/obo/SO_0000468)
863
+ def self.golden_path_fragment
864
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000468')
865
+ end
866
+
867
+ # A set of regions which overlap with minimal polymorphism to form a linear sequence. (SO:cjm)
868
+ # (http://purl.obolibrary.org/obo/SO_0000472)
869
+ def self.tiling_path
870
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000472')
871
+ end
872
+
873
+ # A piece of sequence that makes up a tiling_path (SO:0000472). (SO:ke)
874
+ # (http://purl.obolibrary.org/obo/SO_0000474)
875
+ def self.tiling_path_fragment
876
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000474')
877
+ end
878
+
879
+ # A primary transcript that is never translated into a protein. (SO:ke)
880
+ # (http://purl.obolibrary.org/obo/SO_0000483)
881
+ def self.nc_primary_transcript
882
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000483')
883
+ end
884
+
885
+ # The sequence of the 3' exon that is not coding. (SO:ke)
886
+ # (http://purl.obolibrary.org/obo/SO_0000484)
887
+ def self.three_prime_coding_exon_noncoding_region
888
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000484')
889
+ end
890
+
891
+ # The sequence of the 5' exon preceding the start codon. (SO:ke)
892
+ # (http://purl.obolibrary.org/obo/SO_0000486)
893
+ def self.five_prime_coding_exon_noncoding_region
894
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000486')
895
+ end
896
+
897
+ # A continuous piece of sequence similar to the 'virtual contig' concept of the Ensembl database. (SO:ke)
898
+ # (http://purl.obolibrary.org/obo/SO_0000499)
899
+ def self.virtual_sequence
900
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000499')
901
+ end
902
+
903
+ # A region of sequence that is transcribed. This region may cover the transcript of a gene, it may emcompas the sequence covered by all of the transcripts of a alternately spliced gene, or it may cover the region transcribed by a polycistronic transcript. A gene may have 1 or more transcribed regions and a transcribed_region may belong to one or more genes. (SO:ke)
904
+ # (http://purl.obolibrary.org/obo/SO_0000502)
905
+ def self.transcribed_region
906
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000502')
907
+ end
908
+
909
+ # The recognition sequence necessary for endonuclease cleavage of an RNA transcript that is followed by polyadenylation; consensus=AATAAA. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
910
+ # (http://purl.obolibrary.org/obo/SO_0000551)
911
+ def self.polyA_signal_sequence
912
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000551')
913
+ end
914
+
915
+ # The site on an RNA transcript to which will be added adenine residues by post-transcriptional polyadenylation. The boundary between the UTR and the polyA sequence. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
916
+ # (http://purl.obolibrary.org/obo/SO_0000553)
917
+ def self.polyA_site
918
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000553')
919
+ end
920
+
921
+ # A region of chromosome where the spindle fibers attach during mitosis and meiosis. (SO:ke)
922
+ # (http://purl.obolibrary.org/obo/SO_0000577)
923
+ def self.centromere
924
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000577')
925
+ end
926
+
927
+ # A structure consisting of a 7-methylguanosine in 5'-5' triphosphate linkage with the first nucleotide of an mRNA. It is added post-transcriptionally, and is not encoded in the DNA. (http://seqcore.brcf.med.umich.edu/doc/educ/dnapr/mbglossary/mbgloss.html)
928
+ # (http://purl.obolibrary.org/obo/SO_0000581)
929
+ def self.cap
930
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000581')
931
+ end
932
+
933
+ # Group I catalytic introns are large self-splicing ribozymes. They catalyze their own excision from mRNA, tRNA and rRNA precursors in a wide range of organisms. The core secondary structure consists of 9 paired regions (P1-P9). These fold to essentially two domains, the P4-P6 domain (formed from the stacking of P5, P4, P6 and P6a helices) and the P3-P9 domain (formed from the P8, P3, P7 and P9 helices). Group I catalytic introns often have long ORFs inserted in loop regions. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00028)
934
+ # (http://purl.obolibrary.org/obo/SO_0000587)
935
+ def self.group_I_intron
936
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000587')
937
+ end
938
+
939
+ # A self spliced intron. (SO:ke)
940
+ # (http://purl.obolibrary.org/obo/SO_0000588)
941
+ def self.autocatalytically_spliced_intron
942
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000588')
943
+ end
944
+
945
+ # The signal recognition particle (SRP) is a universally conserved ribonucleoprotein. It is involved in the co-translational targeting of proteins to membranes. The eukaryotic SRP consists of a 300-nucleotide 7S RNA and six proteins: SRPs 72, 68, 54, 19, 14, and 9. Archaeal SRP consists of a 7S RNA and homologues of the eukaryotic SRP19 and SRP54 proteins. In most eubacteria, the SRP consists of a 4.5S RNA and the Ffh protein (a homologue of the eukaryotic SRP54 protein). Eukaryotic and archaeal 7S RNAs have very similar secondary structures, with eight helical elements. These fold into the Alu and S domains, separated by a long linker region. Eubacterial SRP is generally a simpler structure, with the M domain of Ffh bound to a region of the 4.5S RNA that corresponds to helix 8 of the eukaryotic and archaeal SRP S domain. Some Gram-positive bacteria (e.g. Bacillus subtilis), however, have a larger SRP RNA that also has an Alu domain. The Alu domain is thought to mediate the peptide chain elongation retardation function of the SRP. The universally conserved helix which interacts with the SRP54/Ffh M domain mediates signal sequence recognition. In eukaryotes and archaea, the SRP19-helix 6 complex is thought to be involved in SRP assembly and stabilizes helix 8 for SRP54 binding. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00017)
946
+ # (http://purl.obolibrary.org/obo/SO_0000590)
947
+ def self.SRP_RNA
948
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000590')
949
+ end
950
+
951
+ # Most box C/D snoRNAs also contain long (>10 nt) sequences complementary to rRNA. Boxes C and D, as well as boxes C' and D', are usually located in close proximity, and form a structure known as the box C/D motif. This motif is important for snoRNA stability, processing, nucleolar targeting and function. A small number of box C/D snoRNAs are involved in rRNA processing; most, however, are known or predicted to serve as guide RNAs in ribose methylation of rRNA. Targeting involves direct base pairing of the snoRNA at the rRNA site to be modified and selection of a rRNA nucleotide a fixed distance from box D or D'. (http://www.bio.umass.edu/biochem/rna-sequence/Yeast_snoRNA_Database/snoRNA_DataBase.html)
952
+ # (http://purl.obolibrary.org/obo/SO_0000593)
953
+ def self.C_D_box_snoRNA
954
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000593')
955
+ end
956
+
957
+ # A short 3'-uridylated RNA that can form a duplex (except for its post-transcriptionally added oligo_U tail (SO:0000609)) with a stretch of mature edited mRNA. (http://www.rna.ucla.edu/index.html)
958
+ # (http://purl.obolibrary.org/obo/SO_0000602)
959
+ def self.guide_RNA
960
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000602')
961
+ end
962
+
963
+ # Group II introns are found in rRNA, tRNA and mRNA of organelles in fungi, plants and protists, and also in mRNA in bacteria. They are large self-splicing ribozymes and have 6 structural domains (usually designated dI to dVI). A subset of group II introns also encode essential splicing proteins in intronic ORFs. The length of these introns can therefore be up to 3kb. Splicing occurs in almost identical fashion to nuclear pre-mRNA splicing with two transesterification steps. The 2' hydroxyl of a bulged adenosine in domain VI attacks the 5' splice site, followed by nucleophilic attack on the 3' splice site by the 3' OH of the upstream exon. Protein machinery is required for splicing in vivo, and long range intron-intron and intron-exon interactions are important for splice site positioning. Group II introns are further sub-classified into groups IIA and IIB which differ in splice site consensus, distance of bulged A from 3' splice site, some tertiary interactions, and intronic ORF phylogeny. (http://www.sanger.ac.uk/Software/Rfam/browse/index.shtml)
964
+ # (http://purl.obolibrary.org/obo/SO_0000603)
965
+ def self.group_II_intron
966
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000603')
967
+ end
968
+
969
+ # A region containing or overlapping no genes that is bounded on either side by a gene, or bounded by a gene and the end of the chromosome. (SO:cjm)
970
+ # (http://purl.obolibrary.org/obo/SO_0000605)
971
+ def self.intergenic_region
972
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000605')
973
+ end
974
+
975
+ # Sequence of about 100 nucleotides of A added to the 3' end of most eukaryotic mRNAs. (SO:ke)
976
+ # (http://purl.obolibrary.org/obo/SO_0000610)
977
+ def self.polyA_sequence
978
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000610')
979
+ end
980
+
981
+ # A pyrimidine rich sequence near the 3' end of an intron to which the 5'end becomes covalently bound during nuclear splicing. The resulting structure resembles a lariat. (SO:ke)
982
+ # (http://purl.obolibrary.org/obo/SO_0000611)
983
+ def self.branch_site
984
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000611')
985
+ end
986
+
987
+ # The polypyrimidine tract is one of the cis-acting sequence elements directing intron removal in pre-mRNA splicing. (http://nar.oupjournals.org/cgi/content/full/25/4/888)
988
+ # (http://purl.obolibrary.org/obo/SO_0000612)
989
+ def self.polypyrimidine_tract
990
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000612')
991
+ end
992
+
993
+ # The base where transcription ends. (SO:ke)
994
+ # (http://purl.obolibrary.org/obo/SO_0000616)
995
+ def self.transcription_end_site
996
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000616')
997
+ end
998
+
999
+ # A specific structure at the end of a linear chromosome, required for the integrity and maintenance of the end. (SO:ma)
1000
+ # (http://purl.obolibrary.org/obo/SO_0000624)
1001
+ def self.telomere
1002
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000624')
1003
+ end
1004
+
1005
+ # A regulatory region which upon binding of transcription factors, suppress the transcription of the gene or genes they control. (SO:ke)
1006
+ # (http://purl.obolibrary.org/obo/SO_0000625)
1007
+ def self.silencer
1008
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000625')
1009
+ end
1010
+
1011
+ # A transcriptional cis regulatory region that when located between a CM and a gene's promoter prevents the CRM from modulating that genes expression. (SO:regcreative)
1012
+ # (http://purl.obolibrary.org/obo/SO_0000627)
1013
+ def self.insulator
1014
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000627')
1015
+ end
1016
+
1017
+ def self.chromosomal_structural_element
1018
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000628')
1019
+ end
1020
+
1021
+ # A repeat region containing tandemly repeated sequences having a unit length of 10 to 40 bp. (http://www.informatics.jax.org/silver/glossary.shtml)
1022
+ # (http://purl.obolibrary.org/obo/SO_0000643)
1023
+ def self.minisatellite
1024
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000643')
1025
+ end
1026
+
1027
+ # Antisense RNA is RNA that is transcribed from the coding, rather than the template, strand of DNA. It is therefore complementary to mRNA. (SO:ke)
1028
+ # (http://purl.obolibrary.org/obo/SO_0000644)
1029
+ def self.antisense_RNA
1030
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000644')
1031
+ end
1032
+
1033
+ # The reverse complement of the primary transcript. (SO:ke)
1034
+ # (http://purl.obolibrary.org/obo/SO_0000645)
1035
+ def self.antisense_primary_transcript
1036
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000645')
1037
+ end
1038
+
1039
+ # A small RNA molecule that is the product of a longer exogenous or endogenous dsRNA, which is either a bimolecular duplex or very long hairpin, processed (via the Dicer pathway) such that numerous siRNAs accumulate from both strands of the dsRNA. SRNAs trigger the cleavage of their target molecules. (PMID:12592000)
1040
+ # (http://purl.obolibrary.org/obo/SO_0000646)
1041
+ def self.siRNA
1042
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000646')
1043
+ end
1044
+
1045
+ # Non-coding RNAs of about 21 nucleotides in length that regulate temporal development; first discovered in C. elegans. (PMID:11081512)
1046
+ # (http://purl.obolibrary.org/obo/SO_0000649)
1047
+ def self.stRNA
1048
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000649')
1049
+ end
1050
+
1051
+ # Ribosomal RNA transcript that structures the small subunit of the ribosome. (SO:ke)
1052
+ # (http://purl.obolibrary.org/obo/SO_0000650)
1053
+ def self.small_subunit_rRNA
1054
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000650')
1055
+ end
1056
+
1057
+ # Ribosomal RNA transcript that structures the large subunit of the ribosome. (SO:ke)
1058
+ # (http://purl.obolibrary.org/obo/SO_0000651)
1059
+ def self.large_subunit_rRNA
1060
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000651')
1061
+ end
1062
+
1063
+ # 5S ribosomal RNA (5S rRNA) is a component of the large ribosomal subunit in both prokaryotes and eukaryotes. In eukaryotes, it is synthesised by RNA polymerase III (the other eukaryotic rRNAs are cleaved from a 45S precursor synthesised by RNA polymerase I). In Xenopus oocytes, it has been shown that fingers 4-7 of the nine-zinc finger transcription factor TFIIIA can bind to the central region of 5S RNA. Thus, in addition to positively regulating 5S rRNA transcription, TFIIIA also stabilizes 5S rRNA until it is required for transcription. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00001)
1064
+ # (http://purl.obolibrary.org/obo/SO_0000652)
1065
+ def self.rRNA_5S
1066
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000652')
1067
+ end
1068
+
1069
+ # A component of the large ribosomal subunit. (SO:ke)
1070
+ # (http://purl.obolibrary.org/obo/SO_0000653)
1071
+ def self.rRNA_28S
1072
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000653')
1073
+ end
1074
+
1075
+ # An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product. (SO:ke)
1076
+ # (http://purl.obolibrary.org/obo/SO_0000655)
1077
+ def self.ncRNA
1078
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000655')
1079
+ end
1080
+
1081
+ # A region of sequence containing one or more repeat units. (SO:ke)
1082
+ # (http://purl.obolibrary.org/obo/SO_0000657)
1083
+ def self.repeat_region
1084
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000657')
1085
+ end
1086
+
1087
+ # A repeat that is located at dispersed sites in the genome. (SO:ke)
1088
+ # (http://purl.obolibrary.org/obo/SO_0000658)
1089
+ def self.dispersed_repeat
1090
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000658')
1091
+ end
1092
+
1093
+ # An intron which is spliced by the spliceosome. (SO:ke)
1094
+ # (http://purl.obolibrary.org/obo/SO_0000662)
1095
+ def self.spliceosomal_intron
1096
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000662')
1097
+ end
1098
+
1099
+ # The sequence of one or more nucleotides added between two adjacent nucleotides in the sequence. (SO:ke)
1100
+ # (http://purl.obolibrary.org/obo/SO_0000667)
1101
+ def self.insertion
1102
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000667')
1103
+ end
1104
+
1105
+ # A match against an EST sequence. (SO:ke)
1106
+ # (http://purl.obolibrary.org/obo/SO_0000668)
1107
+ def self.EST_match
1108
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000668')
1109
+ end
1110
+
1111
+ # An RNA synthesized on a DNA or RNA template by an RNA polymerase. (SO:ma)
1112
+ # (http://purl.obolibrary.org/obo/SO_0000673)
1113
+ def self.transcript
1114
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000673')
1115
+ end
1116
+
1117
+ # A region of nucleotide sequence targeted by a nuclease enzyme. (SO:ma)
1118
+ # (http://purl.obolibrary.org/obo/SO_0000684)
1119
+ def self.nuclease_sensitive_site
1120
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000684')
1121
+ end
1122
+
1123
+ # The space between two bases in a sequence which marks the position where a deletion has occurred. (SO:ke)
1124
+ # (http://purl.obolibrary.org/obo/SO_0000687)
1125
+ def self.deletion_junction
1126
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000687')
1127
+ end
1128
+
1129
+ # A set of subregions selected from sequence contigs which when concatenated form a nonredundant linear sequence. (SO:ls)
1130
+ # (http://purl.obolibrary.org/obo/SO_0000688)
1131
+ def self.golden_path
1132
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000688')
1133
+ end
1134
+
1135
+ # A match against cDNA sequence. (SO:ke)
1136
+ # (http://purl.obolibrary.org/obo/SO_0000689)
1137
+ def self.cDNA_match
1138
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000689')
1139
+ end
1140
+
1141
+ # SNPs are single base pair positions in genomic DNA at which different sequence alternatives exist in normal individuals in some population(s), wherein the least frequent variant has an abundance of 1% or greater. (SO:cb)
1142
+ # (http://purl.obolibrary.org/obo/SO_0000694)
1143
+ def self.SNP
1144
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000694')
1145
+ end
1146
+
1147
+ # A sequence used in experiment. (SO:ke)
1148
+ # (http://purl.obolibrary.org/obo/SO_0000695)
1149
+ def self.reagent
1150
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000695')
1151
+ end
1152
+
1153
+ # A short oligonucleotide sequence, of length on the order of 10's of bases; either single or double stranded. (SO:ma)
1154
+ # (http://purl.obolibrary.org/obo/SO_0000696)
1155
+ def self.oligo
1156
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000696')
1157
+ end
1158
+
1159
+ # A sequence_feature with an extent of zero. (SO:ke)
1160
+ # (http://purl.obolibrary.org/obo/SO_0000699)
1161
+ def self.junction
1162
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000699')
1163
+ end
1164
+
1165
+ # A comment about the sequence. (SO:ke)
1166
+ # (http://purl.obolibrary.org/obo/SO_0000700)
1167
+ def self.remark
1168
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000700')
1169
+ end
1170
+
1171
+ # A region of sequence where the validity of the base calling is questionable. (SO:ke)
1172
+ # (http://purl.obolibrary.org/obo/SO_0000701)
1173
+ def self.possible_base_call_error
1174
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000701')
1175
+ end
1176
+
1177
+ # A region of sequence where there may have been an error in the assembly. (SO:ke)
1178
+ # (http://purl.obolibrary.org/obo/SO_0000702)
1179
+ def self.possible_assembly_error
1180
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000702')
1181
+ end
1182
+
1183
+ # A region of sequence implicated in an experimental result. (SO:ke)
1184
+ # (http://purl.obolibrary.org/obo/SO_0000703)
1185
+ def self.experimental_result_region
1186
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000703')
1187
+ end
1188
+
1189
+ # A region (or regions) that includes all of the sequence elements necessary to encode a functional transcript. A gene may include regulatory regions, transcribed regions and/or other functional sequence regions. (SO:immuno_workshop)
1190
+ # (http://purl.obolibrary.org/obo/SO_0000704)
1191
+ def self.gene
1192
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000704')
1193
+ end
1194
+
1195
+ # Two or more adjcent copies of a region (of length greater than 1). (SO:ke)
1196
+ # (http://purl.obolibrary.org/obo/SO_0000705)
1197
+ def self.tandem_repeat
1198
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000705')
1199
+ end
1200
+
1201
+ # The 3' splice site of the acceptor primary transcript. (SO:ke)
1202
+ # (http://purl.obolibrary.org/obo/SO_0000706)
1203
+ def self.trans_splice_acceptor_site
1204
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000706')
1205
+ end
1206
+
1207
+ # A region of nucleotide sequence corresponding to a known motif. (SO:ke)
1208
+ # (http://purl.obolibrary.org/obo/SO_0000714)
1209
+ def self.nucleotide_motif
1210
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000714')
1211
+ end
1212
+
1213
+ # A motif that is active in RNA sequence. (SO:ke)
1214
+ # (http://purl.obolibrary.org/obo/SO_0000715)
1215
+ def self.RNA_motif
1216
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000715')
1217
+ end
1218
+
1219
+ # A nucleic acid sequence that when read as sequential triplets, has the potential of encoding a sequential string of amino acids. It need not contain the start or stop codon. (SGD:rb)
1220
+ # (http://purl.obolibrary.org/obo/SO_0000717)
1221
+ def self.reading_frame
1222
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000717')
1223
+ end
1224
+
1225
+ # An ordered and oriented set of scaffolds based on somewhat weaker sets of inferential evidence such as one set of mate pair reads together with supporting evidence from ESTs or location of markers from SNP or microsatellite maps, or cytogenetic localization of contained markers. (FB:WG)
1226
+ # (http://purl.obolibrary.org/obo/SO_0000719)
1227
+ def self.ultracontig
1228
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000719')
1229
+ end
1230
+
1231
+ # A region of a DNA molecule where transfer is initiated during the process of conjugation or mobilization. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
1232
+ # (http://purl.obolibrary.org/obo/SO_0000724)
1233
+ def self.oriT
1234
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000724')
1235
+ end
1236
+
1237
+ # The transit_peptide is a short region at the N-terminus of the peptide that directs the protein to an organelle (chloroplast, mitochondrion, microbody or cyanelle). (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
1238
+ # (http://purl.obolibrary.org/obo/SO_0000725)
1239
+ def self.transit_peptide
1240
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000725')
1241
+ end
1242
+
1243
+ # A regulatory_region where more than 1 TF_binding_site together are regulatorily active. (SO:SG)
1244
+ # (http://purl.obolibrary.org/obo/SO_0000727)
1245
+ def self.CRM
1246
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000727')
1247
+ end
1248
+
1249
+ # A gap in the sequence of known length. The unknown bases are filled in with N's. (SO:ke)
1250
+ # (http://purl.obolibrary.org/obo/SO_0000730)
1251
+ def self.gap
1252
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000730')
1253
+ end
1254
+
1255
+ def self.gene_group_regulatory_region
1256
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000752')
1257
+ end
1258
+
1259
+ # The region of sequence that has been inserted and is being propagated by the clone. (SO:ke)
1260
+ # (http://purl.obolibrary.org/obo/SO_0000753)
1261
+ def self.clone_insert
1262
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000753')
1263
+ end
1264
+
1265
+ # A non functional descendent of an rRNA. (SO:ke)
1266
+ # (http://purl.obolibrary.org/obo/SO_0000777)
1267
+ def self.pseudogenic_rRNA
1268
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000777')
1269
+ end
1270
+
1271
+ # A non functional descendent of a tRNA. (SO:ke)
1272
+ # (http://purl.obolibrary.org/obo/SO_0000778)
1273
+ def self.pseudogenic_tRNA
1274
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000778')
1275
+ end
1276
+
1277
+ # A region of a chromosome. (SO:ke)
1278
+ # (http://purl.obolibrary.org/obo/SO_0000830)
1279
+ def self.chromosome_part
1280
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000830')
1281
+ end
1282
+
1283
+ # A region of a gene. (SO:ke)
1284
+ # (http://purl.obolibrary.org/obo/SO_0000831)
1285
+ def self.gene_member_region
1286
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000831')
1287
+ end
1288
+
1289
+ # A region of a transcript. (SO:ke)
1290
+ # (http://purl.obolibrary.org/obo/SO_0000833)
1291
+ def self.transcript_region
1292
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000833')
1293
+ end
1294
+
1295
+ # A region of a mature transcript. (SO:ke)
1296
+ # (http://purl.obolibrary.org/obo/SO_0000834)
1297
+ def self.mature_transcript_region
1298
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000834')
1299
+ end
1300
+
1301
+ # A part of a primary transcript. (SO:ke)
1302
+ # (http://purl.obolibrary.org/obo/SO_0000835)
1303
+ def self.primary_transcript_region
1304
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000835')
1305
+ end
1306
+
1307
+ # A region of an mRNA. (SO:cb)
1308
+ # (http://purl.obolibrary.org/obo/SO_0000836)
1309
+ def self.mRNA_region
1310
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000836')
1311
+ end
1312
+
1313
+ # A region of UTR. (SO:ke)
1314
+ # (http://purl.obolibrary.org/obo/SO_0000837)
1315
+ def self.UTR_region
1316
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000837')
1317
+ end
1318
+
1319
+ # Biological sequence region that can be assigned to a specific subsequence of a polypeptide. (SO:GAR, SO:ke)
1320
+ # (http://purl.obolibrary.org/obo/SO_0000839)
1321
+ def self.polypeptide_region
1322
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000839')
1323
+ end
1324
+
1325
+ # A region within an intron. (SO:ke)
1326
+ # (http://purl.obolibrary.org/obo/SO_0000841)
1327
+ def self.spliceosomal_intron_region
1328
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000841')
1329
+ end
1330
+
1331
+ def self.gene_component_region
1332
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000842')
1333
+ end
1334
+
1335
+ # A region of a CDS. (SO:cb)
1336
+ # (http://purl.obolibrary.org/obo/SO_0000851)
1337
+ def self.CDS_region
1338
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000851')
1339
+ end
1340
+
1341
+ # A region of an exon. (RSC:cb)
1342
+ # (http://purl.obolibrary.org/obo/SO_0000852)
1343
+ def self.exon_region
1344
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000852')
1345
+ end
1346
+
1347
+ # A large polynucleotide in Bacteria and Archaea, which functions as the small subunit of the ribosome. (SO:ke)
1348
+ # (http://purl.obolibrary.org/obo/SO_0001000)
1349
+ def self.rRNA_16S
1350
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001000')
1351
+ end
1352
+
1353
+ # A large polynucleotide in Bacteria and Archaea, which functions as the large subunit of the ribosome. (SO:ke)
1354
+ # (http://purl.obolibrary.org/obo/SO_0001001)
1355
+ def self.rRNA_23S
1356
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001001')
1357
+ end
1358
+
1359
+ # A large polynucleotide which functions as part of the large subunit of the ribosome in some eukaryotes. (RSC:cb)
1360
+ # (http://purl.obolibrary.org/obo/SO_0001002)
1361
+ def self.rRNA_25S
1362
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001002')
1363
+ end
1364
+
1365
+ # A variation that increases or decreases the copy number of a given region. (SO:ke)
1366
+ # (http://purl.obolibrary.org/obo/SO_0001019)
1367
+ def self.copy_number_variation
1368
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001019')
1369
+ end
1370
+
1371
+ # A nucleotide region with either intra-genome or intracellular moblity, of varying length, which often carry the information necessary for transfer and recombination with the host genome. (PMID:14681355)
1372
+ # (http://purl.obolibrary.org/obo/SO_0001037)
1373
+ def self.mobile_genetic_element
1374
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001037')
1375
+ end
1376
+
1377
+ # An MGE that is integrated into the host chromosome. (SO:ke)
1378
+ # (http://purl.obolibrary.org/obo/SO_0001039)
1379
+ def self.integrated_mobile_genetic_element
1380
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001039')
1381
+ end
1382
+
1383
+ # A regulatory_region that modulates the transcription of a gene or genes. (SO:regcreative)
1384
+ # (http://purl.obolibrary.org/obo/SO_0001055)
1385
+ def self.transcriptional_cis_regulatory_region
1386
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001055')
1387
+ end
1388
+
1389
+ # A regulatory_region that modulates splicing. (SO:ke)
1390
+ # (http://purl.obolibrary.org/obo/SO_0001056)
1391
+ def self.splicing_regulatory_region
1392
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001056')
1393
+ end
1394
+
1395
+ # A sequence_alteration is a sequence_feature whose extent is the deviation from another sequence. (SO:ke)
1396
+ # (http://purl.obolibrary.org/obo/SO_0001059)
1397
+ def self.sequence_alteration
1398
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001059')
1399
+ end
1400
+
1401
+ # An immature_peptide_region is the extent of the peptide after it has been translated and before any processing occurs. (EBIBS:GAR)
1402
+ # (http://purl.obolibrary.org/obo/SO_0001063)
1403
+ def self.immature_peptide_region
1404
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001063')
1405
+ end
1406
+
1407
+ # The maximal intersection of exon and UTR. (SO:ke)
1408
+ # (http://purl.obolibrary.org/obo/SO_0001214)
1409
+ def self.noncoding_region_of_exon
1410
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001214')
1411
+ end
1412
+
1413
+ # The region of an exon that encodes for protein sequence. (SO:ke)
1414
+ # (http://purl.obolibrary.org/obo/SO_0001215)
1415
+ def self.coding_region_of_exon
1416
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001215')
1417
+ end
1418
+
1419
+ # A region containing at least one unique origin of replication and a unique termination site. (ISBN:0716719207)
1420
+ # (http://purl.obolibrary.org/obo/SO_0001235)
1421
+ def self.replicon
1422
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001235')
1423
+ end
1424
+
1425
+ # A base is a sequence feature that corresponds to a single unit of a nucleotide polymer. (SO:ke)
1426
+ # (http://purl.obolibrary.org/obo/SO_0001236)
1427
+ def self.base
1428
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001236')
1429
+ end
1430
+
1431
+ # A region of the genome of known length that is composed by ordering and aligning two or more different regions. (SO:ke)
1432
+ # (http://purl.obolibrary.org/obo/SO_0001248)
1433
+ def self.assembly
1434
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001248')
1435
+ end
1436
+
1437
+ # A region which is intended for use in an experiment. (SO:cb)
1438
+ # (http://purl.obolibrary.org/obo/SO_0001409)
1439
+ def self.biomaterial_region
1440
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001409')
1441
+ end
1442
+
1443
+ # A region which is the result of some arbitrary experimental procedure. The procedure may be carried out with biological material or inside a computer. (SO:cb)
1444
+ # (http://purl.obolibrary.org/obo/SO_0001410)
1445
+ def self.experimental_feature
1446
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001410')
1447
+ end
1448
+
1449
+ # A region defined by its disposition to be involved in a biological process. (SO:cb)
1450
+ # (http://purl.obolibrary.org/obo/SO_0001411)
1451
+ def self.biological_region
1452
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001411')
1453
+ end
1454
+
1455
+ # A region that is defined according to its relations with other regions within the same sequence. (SO:cb)
1456
+ # (http://purl.obolibrary.org/obo/SO_0001412)
1457
+ def self.topologically_defined_region
1458
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001412')
1459
+ end
1460
+
1461
+ # Intronic 2 bp region bordering exon. A splice_site that adjacent_to exon and overlaps intron. (SO:cjm, SO:ke)
1462
+ # (http://purl.obolibrary.org/obo/SO_0001419)
1463
+ def self.cis_splice_site
1464
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001419')
1465
+ end
1466
+
1467
+ # Primary transcript region bordering trans-splice junction. (SO:ke)
1468
+ # (http://purl.obolibrary.org/obo/SO_0001420)
1469
+ def self.trans_splice_site
1470
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001420')
1471
+ end
1472
+
1473
+ # SNVs are single nucleotide positions in genomic DNA at which different sequence alternatives exist. (SO:bm)
1474
+ # (http://purl.obolibrary.org/obo/SO_0001483)
1475
+ def self.SNV
1476
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001483')
1477
+ end
1478
+
1479
+ # A region of peptide sequence used to target the polypeptide molecule to a specific organelle. (SO:ke)
1480
+ # (http://purl.obolibrary.org/obo/SO_0001527)
1481
+ def self.peptide_localization_signal
1482
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001527')
1483
+ end
1484
+
1485
+ # A kind of ribosome entry site, specific to Eukaryotic organisms that overlaps part of both 5' UTR and CDS sequence. (SO:ke)
1486
+ # (http://purl.obolibrary.org/obo/SO_0001647)
1487
+ def self.kozak_sequence
1488
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001647')
1489
+ end
1490
+
1491
+ # A binding site that, in the nucleotide molecule, interacts selectively and non-covalently with polypeptide residues. (SO:ke)
1492
+ # (http://purl.obolibrary.org/obo/SO_0001654)
1493
+ def self.nucleotide_to_protein_binding_site
1494
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001654')
1495
+ end
1496
+
1497
+ # A regulatory region that is involved in the control of the process of transcription. (SO:ke)
1498
+ # (http://purl.obolibrary.org/obo/SO_0001679)
1499
+ def self.transcription_regulatory_region
1500
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001679')
1501
+ end
1502
+
1503
+ # A sequence motif is a nucleotide or amino-acid sequence pattern that may have biological significance. (http://en.wikipedia.org/wiki/Sequence_motif)
1504
+ # (http://purl.obolibrary.org/obo/SO_0001683)
1505
+ def self.sequence_motif
1506
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001683')
1507
+ end
1508
+
1509
+ # A biological region implicated in inherited changes caused by mechanisms other than changes in the underlying DNA sequence. (http://en.wikipedia.org/wiki/Epigenetics, SO:ke)
1510
+ # (http://purl.obolibrary.org/obo/SO_0001720)
1511
+ def self.epigenetically_modified_region
1512
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001720')
1513
+ end
1514
+
1515
+ # An assembly region that has been sequenced from both ends resulting in a read_pair (mate_pair). (SO:ke)
1516
+ # (http://purl.obolibrary.org/obo/SO_0001790)
1517
+ def self.paired_end_fragment
1518
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001790')
1519
+ end
1520
+
1521
+ # A region of sequence that is involved in the control of a biological process. (SO:ke)
1522
+ # (http://purl.obolibrary.org/obo/SO_0005836)
1523
+ def self.regulatory_region
1524
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0005836')
1525
+ end
1526
+
1527
+ # A collection of related genes. (SO:ma)
1528
+ # (http://purl.obolibrary.org/obo/SO_0005855)
1529
+ def self.gene_group
1530
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0005855')
1531
+ end
1532
+
1533
+ # The cleaved_peptide_regon is the a region of peptide sequence that is cleaved during maturation. (EBIBS:GAR)
1534
+ # (http://purl.obolibrary.org/obo/SO_0100011)
1535
+ def self.cleaved_peptide_region
1536
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_0100011')
1537
+ end
1538
+
1539
+ # A sequence alteration where the length of the change in the variant is the same as that of the reference. (SO:ke)
1540
+ # (http://purl.obolibrary.org/obo/SO_1000002)
1541
+ def self.substitution
1542
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_1000002')
1543
+ end
1544
+
1545
+ # When no simple or well defined DNA mutation event describes the observed DNA change, the keyword \"complex\" should be used. Usually there are multiple equally plausible explanations for the change. (EBI:www.ebi.ac.uk/mutations/recommendations/mutevent.html)
1546
+ # (http://purl.obolibrary.org/obo/SO_1000005)
1547
+ def self.complex_substitution
1548
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_1000005')
1549
+ end
1550
+
1551
+ # A single nucleotide change which has occurred at the same position of a corresponding nucleotide in a reference sequence. (SO:immuno_workshop)
1552
+ # (http://purl.obolibrary.org/obo/SO_1000008)
1553
+ def self.point_mutation
1554
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_1000008')
1555
+ end
1556
+
1557
+ # A continuous nucleotide sequence is inverted in the same position. (EBI:www.ebi.ac.uk/mutations/recommendations/mutevent.html)
1558
+ # (http://purl.obolibrary.org/obo/SO_1000036)
1559
+ def self.inversion
1560
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_1000036')
1561
+ end
1562
+
1563
+ # A group of genes, whether linked as a cluster or not, that respond to a common regulatory signal. (ISBN:0198506732)
1564
+ # (http://purl.obolibrary.org/obo/SO_1001284)
1565
+ def self.regulon
1566
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_1001284')
1567
+ end
1568
+
1569
+ # The sequence referred to by an entry in a databank such as Genbank or SwissProt. (SO:ke)
1570
+ # (http://purl.obolibrary.org/obo/SO_2000061)
1571
+ def self.databank_entry
1572
+ return RDF::URI.new('http://purl.obolibrary.org/obo/SO_2000061')
1573
+ end
1574
+
1575
+ # Determines whether the given URI is an object property.
1576
+ #
1577
+ # +uri+:: URI that is tested for being an object property
1578
+ def self.is_object_property?(uri)
1579
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:adjacent_to') then
1580
+ return true
1581
+ end
1582
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:complete_evidence_for_feature') then
1583
+ return true
1584
+ end
1585
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:contained_by') then
1586
+ return true
1587
+ end
1588
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:contains') then
1589
+ return true
1590
+ end
1591
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:derives_from') then
1592
+ return true
1593
+ end
1594
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:evidence_for_feature') then
1595
+ return true
7
1596
  end
8
-
9
- def self.has_integral_part
10
- RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:has_integral_part')
1597
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:has_integral_part') then
1598
+ return true
11
1599
  end
12
-
13
- def self.has_part
14
- RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:has_part')
1600
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:has_part') then
1601
+ return true
15
1602
  end
16
-
17
- def self.integral_part_of
18
- RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:integral_part_of')
1603
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:homologous_to') then
1604
+ return true
19
1605
  end
20
-
21
- def self.non_functional_homolog_of
22
- RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:non_functional_homolog_of')
1606
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:integral_part_of') then
1607
+ return true
23
1608
  end
24
-
25
- def self.partial_evidence_for_feature
26
- RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:partial_evidence_for_feature')
1609
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:member_of') then
1610
+ return true
27
1611
  end
28
-
29
- def self.Sequence_Ontology
30
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000000')
1612
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:non_functional_homolog_of') then
1613
+ return true
31
1614
  end
32
-
33
- # A sequence_feature with an extent greater than zero. A nucleotide region is composed of bases and a polypeptide region is composed of amino acids. (SO:ke)
34
- def self.region
35
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000001')
1615
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:orthologous_to') then
1616
+ return true
36
1617
  end
37
-
38
- def self.interior_coding_exon
39
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000004')
1618
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:paralogous_to') then
1619
+ return true
40
1620
  end
41
-
42
- # The many tandem repeats (identical or related) of a short basic repeating unit; many have a base composition or other property different from the genome average that allows them to be separated from the bulk (main band) genomic DNA. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
43
- def self.satellite_DNA
44
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000005')
1621
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:part_of') then
1622
+ return true
45
1623
  end
46
-
47
- # A region amplified by a PCR reaction. (SO:ke)
48
- def self.PCR_product
49
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000006')
1624
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:partial_evidence_for_feature') then
1625
+ return true
50
1626
  end
51
-
52
- # One of a pair of sequencing reads in which the two members of the pair are related by originating at either end of a clone insert. (SO:ls)
53
- def self.read_pair
54
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000007')
1627
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:similar_to') then
1628
+ return true
55
1629
  end
1630
+ return false
1631
+ end
56
1632
 
57
- # A small non coding RNA sequence, present in the cytoplasm. (SO:ke)
58
- def self.scRNA
59
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000013')
60
- end
1633
+ # Determines whether the given URI is a datatype property.
1634
+ #
1635
+ # +uri+:: URI that is tested for being a datatype property
1636
+ def self.is_datatype_property?(uri)
1637
+ return false
1638
+ end
61
1639
 
62
- # A collection of match parts. (SO:ke)
63
- def self.match_set
64
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000038')
1640
+ # Determines whether the given URI is a class.
1641
+ #
1642
+ # +uri+:: URI that is tested for being a class
1643
+ def self.is_class?(uri)
1644
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000000') then
1645
+ return true
65
1646
  end
66
-
67
- # A part of a match, for example an hsp from blast is a match_part. (SO:ke)
68
- def self.match_part
69
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000039')
1647
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000001') then
1648
+ return true
70
1649
  end
71
-
72
- # A part of a gene, that has no other route in the ontology back to region. This concept is necessary for logical inference as these parts must have the properties of region. It also allows us to associate all the parts of genes with a gene. (SO:ke)
73
- def self.gene_part
74
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000050')
1650
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000004') then
1651
+ return true
75
1652
  end
76
-
77
- # A regulatory element of an operon to which activators or repressors bind thereby effecting translation of genes in that operon. (SO:ma)
78
- def self.operator
79
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000057')
1653
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000005') then
1654
+ return true
80
1655
  end
81
-
82
- # A binding site that, of a nucleotide molecule, that interacts selectively and non-covalently with polypeptide residues of a nuclease. (SO:cb)
83
- def self.nuclease_binding_site
84
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000059')
1656
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000006') then
1657
+ return true
85
1658
  end
86
-
87
- # A transposon or insertion sequence. An element that can insert in a variety of DNA sequences. (http://www.sci.sdsu.edu/~smaloy/Glossary/T.html)
88
- def self.transposable_element
89
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000101')
1659
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000007') then
1660
+ return true
90
1661
  end
91
-
92
- # A match to an EST or cDNA sequence. (SO:ke)
93
- def self.expressed_sequence_match
94
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000102')
1662
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000013') then
1663
+ return true
95
1664
  end
96
-
97
- # The end of the clone insert. (SO:ke)
98
- def self.clone_insert_end
99
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000103')
1665
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000038') then
1666
+ return true
100
1667
  end
101
-
102
- # A sequence of amino acids linked by peptide bonds which may lack appreciable tertiary structure and may not be liable to irreversible denaturation. (SO:ma)
103
- def self.polypeptide
104
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000104')
1668
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000039') then
1669
+ return true
105
1670
  end
106
-
107
- # A sequence_variant is a non exact copy of a sequence_feature or genome exhibiting one or more sequence_alteration. (SO:ke)
108
- def self.sequence_variant_obs
109
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000109')
1671
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000050') then
1672
+ return true
110
1673
  end
111
-
112
- # An extent of biological sequence. (SO:ke)
113
- def self.sequence_feature
114
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000110')
1674
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000057') then
1675
+ return true
115
1676
  end
116
-
117
- # An oligo to which new deoxyribonucleotides can be added by DNA polymerase. (SO:ke)
118
- def self.primer
119
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000112')
1677
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000059') then
1678
+ return true
120
1679
  end
121
-
122
- # A viral sequence which has integrated into a host genome. (SO:ke)
123
- def self.proviral_region
124
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000113')
1680
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000101') then
1681
+ return true
125
1682
  end
126
-
127
- # A methylated deoxy-cytosine. (SO:ke)
128
- def self.methylated_C
129
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000114')
1683
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000102') then
1684
+ return true
130
1685
  end
131
-
132
- # A primary transcript that, at least in part, encodes one or more proteins. (SO:ke)
133
- def self.protein_coding_primary_transcript
134
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000120')
1686
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000103') then
1687
+ return true
135
1688
  end
136
-
137
- # Region in mRNA where ribosome assembles. (SO:ke)
138
- def self.ribosome_entry_site
139
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000139')
1689
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000104') then
1690
+ return true
140
1691
  end
141
-
142
- # A sequence segment located within the five prime end of an mRNA that causes premature termination of translation. (SO:as)
143
- def self.attenuator
144
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000140')
1692
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000109') then
1693
+ return true
145
1694
  end
146
-
147
- # The sequence of DNA located either at the end of the transcript that causes RNA polymerase to terminate transcription. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
148
- def self.terminator
149
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000141')
1695
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000110') then
1696
+ return true
150
1697
  end
151
-
152
- # A region of known length which may be used to manufacture a longer region. (SO:ke)
153
- def self.assembly_component
154
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000143')
1698
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000112') then
1699
+ return true
155
1700
  end
156
-
157
- # A region of the transcript sequence within a gene which is not removed from the primary RNA transcript by RNA splicing. (SO:ke)
158
- def self.exon
159
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000147')
1701
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000113') then
1702
+ return true
160
1703
  end
161
-
162
- # One or more contigs that have been ordered and oriented using end-read information. Contains gaps that are filled with N's. (SO:ls)
163
- def self.supercontig
164
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000148')
1704
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000114') then
1705
+ return true
165
1706
  end
166
-
167
- # A contiguous sequence derived from sequence assembly. Has no gaps, but may contain N's from unavailable bases. (SO:ls)
168
- def self.contig
169
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000149')
1707
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000120') then
1708
+ return true
170
1709
  end
171
-
172
- # A sequence obtained from a single sequencing experiment. Typically a read is produced when a base calling program interprets information from a chromatogram trace file produced from a sequencing machine. (SO:rd)
173
- def self.read
174
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000150')
1710
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000139') then
1711
+ return true
175
1712
  end
176
-
177
- # A piece of DNA that has been inserted in a vector so that it can be propagated in a host bacterium or some other organism. (SO:ke)
178
- def self.clone
179
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000151')
1713
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000140') then
1714
+ return true
180
1715
  end
181
-
182
- # The point at which one or more contiguous nucleotides were excised. (SO:ke)
183
- def self.deletion
184
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000159')
1716
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000141') then
1717
+ return true
185
1718
  end
186
-
187
- # A modified RNA base in which adenine has been methylated. (SO:ke)
188
- def self.methylated_A
189
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000161')
1719
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000143') then
1720
+ return true
190
1721
  end
191
-
192
- # Consensus region of primary transcript bordering junction of splicing. A region that overlaps exactly 2 base and adjacent_to splice_junction. (SO:cjm, SO:ke)
193
- def self.splice_site
194
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000162')
1722
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000147') then
1723
+ return true
195
1724
  end
196
-
197
- # Intronic 2 bp region bordering the exon, at the 5' edge of the intron. A splice_site that is downstream_adjacent_to exon and starts intron. (http://www.ucl.ac.uk/~ucbhjow/b241/glossary.html, SO:cjm, SO:ke)
198
- def self.five_prime_cis_splice_site
199
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000163')
1725
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000148') then
1726
+ return true
200
1727
  end
201
-
202
- # Intronic 2 bp region bordering the exon, at the 3' edge of the intron. A splice_site that is upstream_adjacent_to exon and finishes intron. (http://www.ucl.ac.uk/~ucbhjow/b241/glossary.html, SO:cjm, SO:ke)
203
- def self.three_prime_cis_splice_site
204
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000164')
1728
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000149') then
1729
+ return true
205
1730
  end
206
-
207
- # A cis-acting sequence that increases the utilization of (some) eukaryotic promoters, and can function in either orientation and in any location (upstream or downstream) relative to the promoter. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
208
- def self.enhancer
209
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000165')
1731
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000150') then
1732
+ return true
210
1733
  end
211
-
212
- # A regulatory_region composed of the TSS(s) and binding sites for TF_complexes of the basal transcription machinery. (SO:regcreative)
213
- def self.promoter
214
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000167')
1734
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000151') then
1735
+ return true
215
1736
  end
216
-
217
- # A nucleotide match against a sequence from another organism. (SO:ma)
218
- def self.cross_genome_match
219
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000177')
1737
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000159') then
1738
+ return true
220
1739
  end
221
-
222
- # A group of contiguous genes transcribed as a single (polycistronic) mRNA from a single regulatory region. (SO:ma)
223
- def self.operon
224
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000178')
1740
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000161') then
1741
+ return true
225
1742
  end
226
-
227
- # The start of the clone insert. (SO:ke)
228
- def self.clone_insert_start
229
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000179')
1743
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000162') then
1744
+ return true
230
1745
  end
231
-
232
- # A match against a translated sequence. (SO:ke)
233
- def self.translated_nucleotide_match
234
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000181')
1746
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000163') then
1747
+ return true
235
1748
  end
236
-
237
- # A region of the gene which is not transcribed. (SO:ke)
238
- def self.non_transcribed_region
239
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000183')
1749
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000164') then
1750
+ return true
240
1751
  end
241
-
242
- # A transcript that in its initial state requires modification to be functional. (SO:ma)
243
- def self.primary_transcript
244
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000185')
1752
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000165') then
1753
+ return true
245
1754
  end
246
-
247
- # A group of characterized repeat sequences. (SO:ke)
248
- def self.repeat_family
249
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000187')
1755
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000167') then
1756
+ return true
250
1757
  end
251
-
252
- # A region of a primary transcript that is transcribed, but removed from within the transcript by splicing together the sequences (exons) on either side of it. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
253
- def self.intron
254
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000188')
1758
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000177') then
1759
+ return true
255
1760
  end
256
-
257
- # A DNA fragment used as a reagent to detect the polymorphic genomic loci by hybridizing against the genomic DNA digested with a given restriction enzyme. (GOC:pj)
258
- def self.RFLP_fragment
259
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000193')
1761
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000178') then
1762
+ return true
260
1763
  end
261
-
262
- # An exon whereby at least one base is part of a codon (here, 'codon' is inclusive of the stop_codon). (SO:ke)
263
- def self.coding_exon
264
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000195')
1764
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000179') then
1765
+ return true
265
1766
  end
266
-
267
- # The sequence of the five_prime_coding_exon that codes for protein. (SO:cjm)
268
- def self.five_prime_coding_exon_coding_region
269
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000196')
1767
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000181') then
1768
+ return true
270
1769
  end
271
-
272
- # The sequence of the three_prime_coding_exon that codes for protein. (SO:cjm)
273
- def self.three_prime_coding_exon_coding_region
274
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000197')
1770
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000183') then
1771
+ return true
275
1772
  end
276
-
277
- # An exon that does not contain any codons. (SO:ke)
278
- def self.noncoding_exon
279
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000198')
1773
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000185') then
1774
+ return true
280
1775
  end
281
-
282
- # The 5' most coding exon. (SO:ke)
283
- def self.five_prime_coding_exon
284
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000200')
1776
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000187') then
1777
+ return true
285
1778
  end
286
-
287
- # Messenger RNA sequences that are untranslated and lie five prime or three prime to sequences which are translated. (SO:ke)
288
- def self.UTR
289
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000203')
1779
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000188') then
1780
+ return true
290
1781
  end
291
-
292
- # A region at the 5' end of a mature transcript (preceding the initiation codon) that is not translated into a protein. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
293
- def self.five_prime_UTR
294
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000204')
1782
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000193') then
1783
+ return true
295
1784
  end
296
-
297
- # A region at the 3' end of a mature transcript (following the stop codon) that is not translated into a protein. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
298
- def self.three_prime_UTR
299
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000205')
1785
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000195') then
1786
+ return true
300
1787
  end
301
-
302
- # A primary transcript encoding a ribosomal RNA. (SO:ke)
303
- def self.rRNA_primary_transcript
304
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000209')
1788
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000196') then
1789
+ return true
305
1790
  end
306
-
307
- # A transcript which has undergone the necessary modifications, if any, for its function. In eukaryotes this includes, for example, processing of introns, cleavage, base modification, and modifications to the 5' and/or the 3' ends, other than addition of bases. In bacteria functional mRNAs are usually not modified. (SO:ke)
308
- def self.mature_transcript
309
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000233')
1791
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000197') then
1792
+ return true
310
1793
  end
311
-
312
- # Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns. (SO:ma)
313
- def self.mRNA
314
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000234')
1794
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000198') then
1795
+ return true
315
1796
  end
316
-
317
- # A region of a nucleotide molecule that binds a Transcription Factor or Transcription Factor complex [GO:0005667]. (SO:ke)
318
- def self.TF_binding_site
319
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000235')
1797
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000200') then
1798
+ return true
320
1799
  end
321
-
322
- # The in-frame interval between the stop codons of a reading frame which when read as sequential triplets, has the potential of encoding a sequential string of amino acids. TER(NNN)nTER. (SGD:rb, SO:ma)
323
- def self.ORF
324
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000236')
1800
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000203') then
1801
+ return true
325
1802
  end
326
-
327
- # The sequences extending on either side of a specific region. (SO:ke)
328
- def self.flanking_region
329
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000239')
1803
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000204') then
1804
+ return true
330
1805
  end
331
-
332
- # RNA that comprises part of a ribosome, and that can provide both structural scaffolding and catalytic activity. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html, ISBN:0198506732)
333
- def self.rRNA
334
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000252')
1806
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000205') then
1807
+ return true
335
1808
  end
336
-
337
- # Transfer RNA (tRNA) molecules are approximately 80 nucleotides in length. Their secondary structure includes four short double-helical elements and three loops (D, anti-codon, and T loops). Further hydrogen bonds mediate the characteristic L-shaped molecular structure. Transfer RNAs have two regions of fundamental functional importance: the anti-codon, which is responsible for specific mRNA codon recognition, and the 3' end, to which the tRNA's corresponding amino acid is attached (by aminoacyl-tRNA synthetases). Transfer RNAs cope with the degeneracy of the genetic code in two manners: having more than one tRNA (with a specific anti-codon) for a particular amino acid; and 'wobble' base-pairing, i.e. permitting non-standard base-pairing at the 3rd anti-codon position. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00005, ISBN:0198506732)
338
- def self.tRNA
339
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000253')
1809
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000209') then
1810
+ return true
340
1811
  end
341
-
342
- # A small nuclear RNA molecule involved in pre-mRNA splicing and processing. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html, PMID:11733745, WB:ems)
343
- def self.snRNA
344
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000274')
1812
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000233') then
1813
+ return true
345
1814
  end
346
-
347
- # A snoRNA (small nucleolar RNA) is any one of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing or modifications of many RNAs, mostly ribosomal RNAs (rRNAs) though snoRNAs are also known to target other classes of RNA, including spliceosomal RNAs, tRNAs, and mRNAs via a stretch of sequence that is complementary to a sequence in the targeted RNA. (GOC:kgc)
348
- def self.snoRNA
349
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000275')
1815
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000234') then
1816
+ return true
350
1817
  end
351
-
352
- # Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors. (PMID:12592000)
353
- def self.miRNA
354
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000276')
1818
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000235') then
1819
+ return true
355
1820
  end
356
-
357
- # A repeat_region containing repeat_units (2 to 4 bp) that is repeated multiple times in tandem. (http://www.informatics.jax.org/silver/glossary.shtml)
358
- def self.microsatellite
359
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000289')
1821
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000236') then
1822
+ return true
360
1823
  end
361
-
362
- # The sequence is complementarily repeated on the opposite strand. It is a palindrome, and it may, or may not be hyphenated. Examples: GCTGATCAGC, or GCTGA-----TCAGC. (SO:ke)
363
- def self.inverted_repeat
364
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000294')
1824
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000239') then
1825
+ return true
365
1826
  end
366
-
367
- # The origin of replication; starting site for duplication of a nucleic acid molecule to give two identical copies. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
368
- def self.origin_of_replication
369
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000296')
1827
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000252') then
1828
+ return true
370
1829
  end
371
-
372
- # Part of the primary transcript that is clipped off during processing. (SO:ke)
373
- def self.clip
374
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000303')
1830
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000253') then
1831
+ return true
375
1832
  end
376
-
377
- # A modified nucleotide, i.e. a nucleotide other than A, T, C. G. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
378
- def self.modified_base
379
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000305')
1833
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000274') then
1834
+ return true
380
1835
  end
381
-
382
- # A nucleotide modified by methylation. (SO:ke)
383
- def self.methylated_base_feature
384
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000306')
1836
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000275') then
1837
+ return true
385
1838
  end
386
-
387
- # Regions of a few hundred to a few thousand bases in vertebrate genomes that are relatively GC and CpG rich; they are typically unmethylated and often found near the 5' ends of genes. (SO:rd)
388
- def self.CpG_island
389
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000307')
1839
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000276') then
1840
+ return true
390
1841
  end
391
-
392
- # A repeat where the same sequence is repeated in the same direction. Example: GCTGA-----GCTGA. (SO:ke)
393
- def self.direct_repeat
394
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000314')
1842
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000289') then
1843
+ return true
395
1844
  end
396
-
397
- # The first base where RNA polymerase begins to synthesize the RNA transcript. (SO:ke)
398
- def self.TSS
399
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000315')
1845
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000294') then
1846
+ return true
400
1847
  end
401
-
402
- # A contiguous sequence which begins with, and includes, a start codon and ends with, and includes, a stop codon. (SO:ma)
403
- def self.CDS
404
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000316')
1848
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000296') then
1849
+ return true
405
1850
  end
406
-
407
- # First codon to be translated by a ribosome. (SO:ke)
408
- def self.start_codon
409
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000318')
1851
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000303') then
1852
+ return true
410
1853
  end
411
-
412
- # In mRNA, a set of three nucleotides that indicates the end of information for protein synthesis. (SO:ke)
413
- def self.stop_codon
414
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000319')
1854
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000305') then
1855
+ return true
415
1856
  end
416
-
417
- # A nucleotide sequence that may be used to identify a larger sequence. (SO:ke)
418
- def self.tag
419
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000324')
1857
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000306') then
1858
+ return true
420
1859
  end
421
-
422
- # A primary transcript encoding a large ribosomal subunit RNA. (SO:ke)
423
- def self.rRNA_large_subunit_primary_transcript
424
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000325')
1860
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000307') then
1861
+ return true
425
1862
  end
426
-
427
- # A short diagnostic sequence tag, serial analysis of gene expression (SAGE), that allows the quantitative and simultaneous analysis of a large number of transcripts. (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7570003&dopt=Abstract)
428
- def self.SAGE_tag
429
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000326')
1863
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000314') then
1864
+ return true
430
1865
  end
431
-
432
- # Region of sequence similarity by descent from a common ancestor. (SO:ke)
433
- def self.conserved_region
434
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000330')
1866
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000315') then
1867
+ return true
435
1868
  end
436
-
437
- # Short (typically a few hundred base pairs) DNA sequence that has a single occurrence in a genome and whose location and base sequence are known. (http://www.biospace.com)
438
- def self.STS
439
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000331')
1869
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000316') then
1870
+ return true
440
1871
  end
441
-
442
- # Coding region of sequence similarity by descent from a common ancestor. (SO:ke)
443
- def self.coding_conserved_region
444
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000332')
1872
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000318') then
1873
+ return true
445
1874
  end
446
-
447
- # The boundary between two exons in a processed transcript. (SO:ke)
448
- def self.exon_junction
449
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000333')
1875
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000319') then
1876
+ return true
450
1877
  end
451
-
452
- # Non-coding region of sequence similarity by descent from a common ancestor. (SO:ke)
453
- def self.nc_conserved_region
454
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000334')
1878
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000324') then
1879
+ return true
455
1880
  end
456
-
457
- # A sequence that closely resembles a known functional gene, at another locus within a genome, that is non-functional as a consequence of (usually several) mutations that prevent either its transcription or translation (or both). In general, pseudogenes result from either reverse transcription of a transcript of their \"normal\" paralog (SO:0000043) (in which case the pseudogene typically lacks introns and includes a poly(A) tail) or from recombination (SO:0000044) (in which case the pseudogene is typically a tandem duplication of its \"normal\" paralog). (http://www.ucl.ac.uk/~ucbhjow/b241/glossary.html)
458
- def self.pseudogene
459
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000336')
1881
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000325') then
1882
+ return true
460
1883
  end
461
-
462
- # A double stranded RNA duplex, at least 20bp long, used experimentally to inhibit gene function by RNA interference. (SO:rd)
463
- def self.RNAi_reagent
464
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000337')
1884
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000326') then
1885
+ return true
465
1886
  end
466
-
467
- # Structural unit composed of a nucleic acid molecule which controls its own replication through the interaction of specific proteins at one or more origins of replication. (SO:ma)
468
- def self.chromosome
469
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000340')
1887
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000330') then
1888
+ return true
470
1889
  end
471
-
472
- # A cytologically distinguishable feature of a chromosome, often made visible by staining, and usually alternating light and dark. (SO:ma)
473
- def self.chromosome_band
474
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000341')
1890
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000331') then
1891
+ return true
475
1892
  end
476
-
477
- # A region of sequence, aligned to another sequence with some statistical significance, using an algorithm such as BLAST or SIM4. (SO:ke)
478
- def self.match
479
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000343')
1893
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000332') then
1894
+ return true
480
1895
  end
481
-
482
- # Region of a transcript that regulates splicing. (SO:ke)
483
- def self.splice_enhancer
484
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000344')
1896
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000333') then
1897
+ return true
485
1898
  end
486
-
487
- # A tag produced from a single sequencing read from a cDNA clone or PCR product; typically a few hundred base pairs long. (SO:ke)
488
- def self.EST
489
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000345')
1899
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000334') then
1900
+ return true
490
1901
  end
491
-
492
- # A match against a nucleotide sequence. (SO:ke)
493
- def self.nucleotide_match
494
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000347')
1902
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000336') then
1903
+ return true
495
1904
  end
496
-
497
- # A match against a protein sequence. (SO:ke)
498
- def self.protein_match
499
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000349')
1905
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000337') then
1906
+ return true
500
1907
  end
501
-
502
- # A sequence of nucleotides that has been algorithmically derived from an alignment of two or more different sequences. (SO:ma)
503
- def self.sequence_assembly
504
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000353')
1908
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000340') then
1909
+ return true
505
1910
  end
506
-
507
- # A set of (usually) three nucleotide bases in a DNA or RNA sequence, which together code for a unique amino acid or the termination of translation and are contained within the CDS. (http://www.everythingbio.com/glos/definition.php?word=codon, SO:ke)
508
- def self.codon
509
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000360')
1911
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000341') then
1912
+ return true
510
1913
  end
511
-
512
- # The junction where an insertion occurred. (SO:ke)
513
- def self.insertion_site
514
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000366')
1914
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000343') then
1915
+ return true
515
1916
  end
516
-
517
- # The junction in a genome where a transposable_element has inserted. (SO:ke)
518
- def self.transposable_element_insertion_site
519
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000368')
1917
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000344') then
1918
+ return true
520
1919
  end
521
-
522
- # A non-coding RNA, usually with a specific secondary structure, that acts to regulate gene expression. (SO:ma)
523
- def self.small_regulatory_ncRNA
524
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000370')
1920
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000345') then
1921
+ return true
525
1922
  end
526
-
527
- # An RNA sequence that has catalytic activity with or without an associated ribonucleoprotein. (RSC:cb)
528
- def self.enzymatic_RNA
529
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000372')
1923
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000347') then
1924
+ return true
530
1925
  end
531
-
532
- # An RNA with catalytic activity. (SO:ma)
533
- def self.ribozyme
534
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000374')
1926
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000349') then
1927
+ return true
535
1928
  end
536
-
537
- # 5_8S ribosomal RNA (5. 8S rRNA) is a component of the large subunit of the eukaryotic ribosome. It is transcribed by RNA polymerase I as part of the 45S precursor that also contains 18S and 28S rRNA. Functionally, it is thought that 5.8S rRNA may be involved in ribosome translocation. It is also known to form covalent linkage to the p53 tumour suppressor protein. 5_8S rRNA is also found in archaea. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00002)
538
- def self.rRNA_5_8S
539
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000375')
1929
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000353') then
1930
+ return true
540
1931
  end
541
-
542
- # A small catalytic RNA motif that catalyzes self-cleavage reaction. Its name comes from its secondary structure which resembles a carpenter's hammer. The hammerhead ribozyme is involved in the replication of some viroid and some satellite RNAs. (PMID:2436805)
543
- def self.hammerhead_ribozyme
544
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000380')
1932
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000360') then
1933
+ return true
545
1934
  end
546
-
547
- # The RNA molecule essential for the catalytic activity of RNase MRP, an enzymatically active ribonucleoprotein with two distinct roles in eukaryotes. In mitochondria it plays a direct role in the initiation of mitochondrial DNA replication. In the nucleus it is involved in precursor rRNA processing, where it cleaves the internal transcribed spacer 1 between 18S and 5.8S rRNAs. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00030)
548
- def self.RNase_MRP_RNA
549
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000385')
1935
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000366') then
1936
+ return true
550
1937
  end
551
-
552
- # The RNA component of Ribonuclease P (RNase P), a ubiquitous endoribonuclease, found in archaea, bacteria and eukarya as well as chloroplasts and mitochondria. Its best characterized activity is the generation of mature 5 prime ends of tRNAs by cleaving the 5 prime leader elements of precursor-tRNAs. Cellular RNase Ps are ribonucleoproteins. RNA from bacterial RNase Ps retains its catalytic activity in the absence of the protein subunit, i.e. it is a ribozyme. Isolated eukaryotic and archaeal RNase P RNA has not been shown to retain its catalytic function, but is still essential for the catalytic activity of the holoenzyme. Although the archaeal and eukaryotic holoenzymes have a much greater protein content than the bacterial ones, the RNA cores from all the three lineages are homologous. Helices corresponding to P1, P2, P3, P4, and P10/11 are common to all cellular RNase P RNAs. Yet, there is considerable sequence variation, particularly among the eukaryotic RNAs. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00010)
553
- def self.RNase_P_RNA
554
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000386')
1938
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000368') then
1939
+ return true
555
1940
  end
556
-
557
- # The RNA component of telomerase, a reverse transcriptase that synthesizes telomeric DNA. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00025)
558
- def self.telomerase_RNA
559
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000390')
1941
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000370') then
1942
+ return true
560
1943
  end
561
-
562
- # U1 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Its 5' end forms complementary base pairs with the 5' splice junction, thus defining the 5' donor site of an intron. There are significant differences in sequence and secondary structure between metazoan and yeast U1 snRNAs, the latter being much longer (568 nucleotides as compared to 164 nucleotides in human). Nevertheless, secondary structure predictions suggest that all U1 snRNAs share a 'common core' consisting of helices I, II, the proximal region of III, and IV. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00003)
563
- def self.U1_snRNA
564
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000391')
1944
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000372') then
1945
+ return true
565
1946
  end
566
-
567
- # U2 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Complementary binding between U2 snRNA (in an area lying towards the 5' end but 3' to hairpin I) and the branchpoint sequence (BPS) of the intron results in the bulging out of an unpaired adenine, on the BPS, which initiates a nucleophilic attack at the intronic 5' splice site, thus starting the first of two transesterification reactions that mediate splicing. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00004)
568
- def self.U2_snRNA
569
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000392')
1947
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000374') then
1948
+ return true
570
1949
  end
571
-
572
- # U4 small nuclear RNA (U4 snRNA) is a component of the major U2-dependent spliceosome. It forms a duplex with U6, and with each splicing round, it is displaced from U6 (and the spliceosome) in an ATP-dependent manner, allowing U6 to refold and create the active site for splicing catalysis. A recycling process involving protein Prp24 re-anneals U4 and U6. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00015)
573
- def self.U4_snRNA
574
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000393')
1950
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000375') then
1951
+ return true
575
1952
  end
576
-
577
- # An snRNA required for the splicing of the minor U12-dependent class of eukaryotic nuclear introns. It forms a base paired complex with U6atac_snRNA (SO:0000397). (PMID:=12409455)
578
- def self.U4atac_snRNA
579
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000394')
1953
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000380') then
1954
+ return true
580
1955
  end
581
-
582
- # U5 RNA is a component of both types of known spliceosome. The precise function of this molecule is unknown, though it is known that the 5' loop is required for splice site selection and p220 binding, and that both the 3' stem-loop and the Sm site are important for Sm protein binding and cap methylation. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00020)
583
- def self.U5_snRNA
584
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000395')
1956
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000385') then
1957
+ return true
585
1958
  end
586
-
587
- # U6 snRNA is a component of the spliceosome which is involved in splicing pre-mRNA. The putative secondary structure consensus base pairing is confined to a short 5' stem loop, but U6 snRNA is thought to form extensive base-pair interactions with U4 snRNA. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00015)
588
- def self.U6_snRNA
589
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000396')
1959
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000386') then
1960
+ return true
590
1961
  end
591
-
592
- # U6atac_snRNA is an snRNA required for the splicing of the minor U12-dependent class of eukaryotic nuclear introns. It forms a base paired complex with U4atac_snRNA (SO:0000394). (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=retrieve&db=pubmed&list_uids=12409455&dopt=Abstract)
593
- def self.U6atac_snRNA
594
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000397')
1962
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000390') then
1963
+ return true
595
1964
  end
596
-
597
- # U11 snRNA plays a role in splicing of the minor U12-dependent class of eukaryotic nuclear introns, similar to U1 snRNA in the major class spliceosome it base pairs to the conserved 5' splice site sequence. (PMID:9622129)
598
- def self.U11_snRNA
599
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000398')
1965
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000391') then
1966
+ return true
600
1967
  end
601
-
602
- # The U12 small nuclear (snRNA), together with U4atac/U6atac, U5, and U11 snRNAs and associated proteins, forms a spliceosome that cleaves a divergent class of low-abundance pre-mRNA introns. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00007)
603
- def self.U12_snRNA
604
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000399')
1968
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000392') then
1969
+ return true
605
1970
  end
606
-
607
- # U14 small nucleolar RNA (U14 snoRNA) is required for early cleavages of eukaryotic precursor rRNAs. In yeasts, this molecule possess a stem-loop region (known as the Y-domain) which is essential for function. A similar structure, but with a different consensus sequence, is found in plants, but is absent in vertebrates. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00016, PMID:2551119)
608
- def self.U14_snoRNA
609
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000403')
1971
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000393') then
1972
+ return true
610
1973
  end
611
-
612
- # A family of RNAs are found as part of the enigmatic vault ribonucleoprotein complex. The complex consists of a major vault protein (MVP), two minor vault proteins (VPARP and TEP1), and several small untranslated RNA molecules. It has been suggested that the vault complex is involved in drug resistance. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00006)
613
- def self.vault_RNA
614
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000404')
1974
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000394') then
1975
+ return true
615
1976
  end
616
-
617
- # Y RNAs are components of the Ro ribonucleoprotein particle (Ro RNP), in association with Ro60 and La proteins. The Y RNAs and Ro60 and La proteins are well conserved, but the function of the Ro RNP is not known. In humans the RNA component can be one of four small RNAs: hY1, hY3, hY4 and hY5. These small RNAs are predicted to fold into a conserved secondary structure containing three stem structures. The largest of the four, hY1, contains an additional hairpin. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00019)
618
- def self.Y_RNA
619
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000405')
1977
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000395') then
1978
+ return true
620
1979
  end
621
-
622
- # A large polynucleotide in eukaryotes, which functions as the small subunit of the ribosome. (SO:ke)
623
- def self.rRNA_18S
624
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000407')
1980
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000396') then
1981
+ return true
625
1982
  end
626
-
627
- # A biological_region of sequence that, in the molecule, interacts selectively and non-covalently with other molecules. A region on the surface of a molecule that may interact with another molecule. When applied to polypeptides: Amino acids involved in binding or interactions. It can also apply to an amino acid bond which is represented by the positions of the two flanking amino acids. (EBIBS:GAR, SO:ke)
628
- def self.binding_site
629
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000409')
1983
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000397') then
1984
+ return true
630
1985
  end
631
-
632
- # A binding site that, in the molecule, interacts selectively and non-covalently with polypeptide molecules. (SO:ke)
633
- def self.protein_binding_site
634
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000410')
1986
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000398') then
1987
+ return true
635
1988
  end
636
-
637
- # A region of polynucleotide sequence produced by digestion with a restriction endonuclease. (SO:ke)
638
- def self.restriction_fragment
639
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000412')
1989
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000399') then
1990
+ return true
640
1991
  end
641
-
642
- # A region where the sequence differs from that of a specified sequence. (SO:ke)
643
- def self.sequence_difference
644
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000413')
1992
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000403') then
1993
+ return true
645
1994
  end
646
-
647
- # The signal_peptide is a short region of the peptide located at the N-terminus that directs the protein to be secreted or part of membrane components. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
648
- def self.signal_peptide
649
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000418')
1995
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000404') then
1996
+ return true
650
1997
  end
651
-
652
- # The polypeptide sequence that remains when the cleaved peptide regions have been cleaved from the immature peptide. (EBIBS:GAR, http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html, SO:cb)
653
- def self.mature_protein_region
654
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000419')
1998
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000405') then
1999
+ return true
655
2000
  end
656
-
657
- # A sequence that can autonomously replicate, as a plasmid, when transformed into a bacterial host. (SO:ma)
658
- def self.ARS
659
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000436')
2001
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000407') then
2002
+ return true
660
2003
  end
661
-
662
- # A single stranded oligonucleotide. (SO:ke)
663
- def self.ss_oligo
664
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000441')
2004
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000409') then
2005
+ return true
665
2006
  end
666
-
667
- # A double stranded oligonucleotide. (SO:ke)
668
- def self.ds_oligo
669
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000442')
2007
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000410') then
2008
+ return true
670
2009
  end
671
-
672
- # A 17-28-nt, small interfering RNA derived from transcripts of repetitive elements. (http://www.developmentalcell.com/content/article/abstract?uid=PIIS1534580703002284)
673
- def self.rasiRNA
674
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000454')
2010
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000412') then
2011
+ return true
675
2012
  end
676
-
677
- # A non-functional descendent of a functional entity. (SO:cjm)
678
- def self.pseudogenic_region
679
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000462')
2013
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000413') then
2014
+ return true
680
2015
  end
681
-
682
- # A non-functional descendant of an exon. (SO:ke)
683
- def self.decayed_exon
684
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000464')
2016
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000418') then
2017
+ return true
685
2018
  end
686
-
687
- # One of the pieces of sequence that make up a golden path. (SO:rd)
688
- def self.golden_path_fragment
689
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000468')
2019
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000419') then
2020
+ return true
690
2021
  end
691
-
692
- # A set of regions which overlap with minimal polymorphism to form a linear sequence. (SO:cjm)
693
- def self.tiling_path
694
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000472')
2022
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000436') then
2023
+ return true
695
2024
  end
696
-
697
- # A piece of sequence that makes up a tiling_path (SO:0000472). (SO:ke)
698
- def self.tiling_path_fragment
699
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000474')
2025
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000441') then
2026
+ return true
700
2027
  end
701
-
702
- # A primary transcript that is never translated into a protein. (SO:ke)
703
- def self.nc_primary_transcript
704
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000483')
2028
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000442') then
2029
+ return true
705
2030
  end
706
-
707
- # The sequence of the 3' exon that is not coding. (SO:ke)
708
- def self.three_prime_coding_exon_noncoding_region
709
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000484')
2031
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000454') then
2032
+ return true
710
2033
  end
711
-
712
- # The sequence of the 5' exon preceding the start codon. (SO:ke)
713
- def self.five_prime_coding_exon_noncoding_region
714
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000486')
2034
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000462') then
2035
+ return true
715
2036
  end
716
-
717
- # A continuous piece of sequence similar to the 'virtual contig' concept of the Ensembl database. (SO:ke)
718
- def self.virtual_sequence
719
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000499')
2037
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000464') then
2038
+ return true
720
2039
  end
721
-
722
- # A region of sequence that is transcribed. This region may cover the transcript of a gene, it may emcompas the sequence covered by all of the transcripts of a alternately spliced gene, or it may cover the region transcribed by a polycistronic transcript. A gene may have 1 or more transcribed regions and a transcribed_region may belong to one or more genes. (SO:ke)
723
- def self.transcribed_region
724
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000502')
2040
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000468') then
2041
+ return true
725
2042
  end
726
-
727
- # The recognition sequence necessary for endonuclease cleavage of an RNA transcript that is followed by polyadenylation; consensus=AATAAA. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
728
- def self.polyA_signal_sequence
729
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000551')
2043
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000472') then
2044
+ return true
730
2045
  end
731
-
732
- # The site on an RNA transcript to which will be added adenine residues by post-transcriptional polyadenylation. The boundary between the UTR and the polyA sequence. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
733
- def self.polyA_site
734
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000553')
2046
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000474') then
2047
+ return true
735
2048
  end
736
-
737
- # A region of chromosome where the spindle fibers attach during mitosis and meiosis. (SO:ke)
738
- def self.centromere
739
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000577')
2049
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000483') then
2050
+ return true
740
2051
  end
741
-
742
- # A structure consisting of a 7-methylguanosine in 5'-5' triphosphate linkage with the first nucleotide of an mRNA. It is added post-transcriptionally, and is not encoded in the DNA. (http://seqcore.brcf.med.umich.edu/doc/educ/dnapr/mbglossary/mbgloss.html)
743
- def self.cap
744
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000581')
2052
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000484') then
2053
+ return true
745
2054
  end
746
-
747
- # Group I catalytic introns are large self-splicing ribozymes. They catalyze their own excision from mRNA, tRNA and rRNA precursors in a wide range of organisms. The core secondary structure consists of 9 paired regions (P1-P9). These fold to essentially two domains, the P4-P6 domain (formed from the stacking of P5, P4, P6 and P6a helices) and the P3-P9 domain (formed from the P8, P3, P7 and P9 helices). Group I catalytic introns often have long ORFs inserted in loop regions. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00028)
748
- def self.group_I_intron
749
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000587')
2055
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000486') then
2056
+ return true
750
2057
  end
751
-
752
- # A self spliced intron. (SO:ke)
753
- def self.autocatalytically_spliced_intron
754
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000588')
2058
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000499') then
2059
+ return true
755
2060
  end
756
-
757
- # The signal recognition particle (SRP) is a universally conserved ribonucleoprotein. It is involved in the co-translational targeting of proteins to membranes. The eukaryotic SRP consists of a 300-nucleotide 7S RNA and six proteins: SRPs 72, 68, 54, 19, 14, and 9. Archaeal SRP consists of a 7S RNA and homologues of the eukaryotic SRP19 and SRP54 proteins. In most eubacteria, the SRP consists of a 4.5S RNA and the Ffh protein (a homologue of the eukaryotic SRP54 protein). Eukaryotic and archaeal 7S RNAs have very similar secondary structures, with eight helical elements. These fold into the Alu and S domains, separated by a long linker region. Eubacterial SRP is generally a simpler structure, with the M domain of Ffh bound to a region of the 4.5S RNA that corresponds to helix 8 of the eukaryotic and archaeal SRP S domain. Some Gram-positive bacteria (e.g. Bacillus subtilis), however, have a larger SRP RNA that also has an Alu domain. The Alu domain is thought to mediate the peptide chain elongation retardation function of the SRP. The universally conserved helix which interacts with the SRP54/Ffh M domain mediates signal sequence recognition. In eukaryotes and archaea, the SRP19-helix 6 complex is thought to be involved in SRP assembly and stabilizes helix 8 for SRP54 binding. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00017)
758
- def self.SRP_RNA
759
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000590')
2061
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000502') then
2062
+ return true
760
2063
  end
761
-
762
- # Most box C/D snoRNAs also contain long (>10 nt) sequences complementary to rRNA. Boxes C and D, as well as boxes C' and D', are usually located in close proximity, and form a structure known as the box C/D motif. This motif is important for snoRNA stability, processing, nucleolar targeting and function. A small number of box C/D snoRNAs are involved in rRNA processing; most, however, are known or predicted to serve as guide RNAs in ribose methylation of rRNA. Targeting involves direct base pairing of the snoRNA at the rRNA site to be modified and selection of a rRNA nucleotide a fixed distance from box D or D'. (http://www.bio.umass.edu/biochem/rna-sequence/Yeast_snoRNA_Database/snoRNA_DataBase.html)
763
- def self.C_D_box_snoRNA
764
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000593')
2064
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000551') then
2065
+ return true
765
2066
  end
766
-
767
- # A short 3'-uridylated RNA that can form a duplex (except for its post-transcriptionally added oligo_U tail (SO:0000609)) with a stretch of mature edited mRNA. (http://www.rna.ucla.edu/index.html)
768
- def self.guide_RNA
769
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000602')
2067
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000553') then
2068
+ return true
770
2069
  end
771
-
772
- # Group II introns are found in rRNA, tRNA and mRNA of organelles in fungi, plants and protists, and also in mRNA in bacteria. They are large self-splicing ribozymes and have 6 structural domains (usually designated dI to dVI). A subset of group II introns also encode essential splicing proteins in intronic ORFs. The length of these introns can therefore be up to 3kb. Splicing occurs in almost identical fashion to nuclear pre-mRNA splicing with two transesterification steps. The 2' hydroxyl of a bulged adenosine in domain VI attacks the 5' splice site, followed by nucleophilic attack on the 3' splice site by the 3' OH of the upstream exon. Protein machinery is required for splicing in vivo, and long range intron-intron and intron-exon interactions are important for splice site positioning. Group II introns are further sub-classified into groups IIA and IIB which differ in splice site consensus, distance of bulged A from 3' splice site, some tertiary interactions, and intronic ORF phylogeny. (http://www.sanger.ac.uk/Software/Rfam/browse/index.shtml)
773
- def self.group_II_intron
774
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000603')
2070
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000577') then
2071
+ return true
775
2072
  end
776
-
777
- # A region containing or overlapping no genes that is bounded on either side by a gene, or bounded by a gene and the end of the chromosome. (SO:cjm)
778
- def self.intergenic_region
779
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000605')
2073
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000581') then
2074
+ return true
780
2075
  end
781
-
782
- # Sequence of about 100 nucleotides of A added to the 3' end of most eukaryotic mRNAs. (SO:ke)
783
- def self.polyA_sequence
784
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000610')
2076
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000587') then
2077
+ return true
785
2078
  end
786
-
787
- # A pyrimidine rich sequence near the 3' end of an intron to which the 5'end becomes covalently bound during nuclear splicing. The resulting structure resembles a lariat. (SO:ke)
788
- def self.branch_site
789
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000611')
2079
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000588') then
2080
+ return true
790
2081
  end
791
-
792
- # The polypyrimidine tract is one of the cis-acting sequence elements directing intron removal in pre-mRNA splicing. (http://nar.oupjournals.org/cgi/content/full/25/4/888)
793
- def self.polypyrimidine_tract
794
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000612')
2082
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000590') then
2083
+ return true
795
2084
  end
796
-
797
- # The base where transcription ends. (SO:ke)
798
- def self.transcription_end_site
799
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000616')
2085
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000593') then
2086
+ return true
800
2087
  end
801
-
802
- # A specific structure at the end of a linear chromosome, required for the integrity and maintenance of the end. (SO:ma)
803
- def self.telomere
804
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000624')
2088
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000602') then
2089
+ return true
805
2090
  end
806
-
807
- # A regulatory region which upon binding of transcription factors, suppress the transcription of the gene or genes they control. (SO:ke)
808
- def self.silencer
809
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000625')
2091
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000603') then
2092
+ return true
810
2093
  end
811
-
812
- # A transcriptional cis regulatory region that when located between a CM and a gene's promoter prevents the CRM from modulating that genes expression. (SO:regcreative)
813
- def self.insulator
814
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000627')
2094
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000605') then
2095
+ return true
815
2096
  end
816
-
817
- def self.chromosomal_structural_element
818
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000628')
2097
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000610') then
2098
+ return true
819
2099
  end
820
-
821
- # A repeat region containing tandemly repeated sequences having a unit length of 10 to 40 bp. (http://www.informatics.jax.org/silver/glossary.shtml)
822
- def self.minisatellite
823
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000643')
2100
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000611') then
2101
+ return true
824
2102
  end
825
-
826
- # Antisense RNA is RNA that is transcribed from the coding, rather than the template, strand of DNA. It is therefore complementary to mRNA. (SO:ke)
827
- def self.antisense_RNA
828
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000644')
2103
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000612') then
2104
+ return true
829
2105
  end
830
-
831
- # The reverse complement of the primary transcript. (SO:ke)
832
- def self.antisense_primary_transcript
833
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000645')
2106
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000616') then
2107
+ return true
834
2108
  end
835
-
836
- # A small RNA molecule that is the product of a longer exogenous or endogenous dsRNA, which is either a bimolecular duplex or very long hairpin, processed (via the Dicer pathway) such that numerous siRNAs accumulate from both strands of the dsRNA. SRNAs trigger the cleavage of their target molecules. (PMID:12592000)
837
- def self.siRNA
838
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000646')
2109
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000624') then
2110
+ return true
839
2111
  end
840
-
841
- # Non-coding RNAs of about 21 nucleotides in length that regulate temporal development; first discovered in C. elegans. (PMID:11081512)
842
- def self.stRNA
843
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000649')
2112
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000625') then
2113
+ return true
844
2114
  end
845
-
846
- # Ribosomal RNA transcript that structures the small subunit of the ribosome. (SO:ke)
847
- def self.small_subunit_rRNA
848
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000650')
2115
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000627') then
2116
+ return true
849
2117
  end
850
-
851
- # Ribosomal RNA transcript that structures the large subunit of the ribosome. (SO:ke)
852
- def self.large_subunit_rRNA
853
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000651')
2118
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000628') then
2119
+ return true
854
2120
  end
855
-
856
- # 5S ribosomal RNA (5S rRNA) is a component of the large ribosomal subunit in both prokaryotes and eukaryotes. In eukaryotes, it is synthesised by RNA polymerase III (the other eukaryotic rRNAs are cleaved from a 45S precursor synthesised by RNA polymerase I). In Xenopus oocytes, it has been shown that fingers 4-7 of the nine-zinc finger transcription factor TFIIIA can bind to the central region of 5S RNA. Thus, in addition to positively regulating 5S rRNA transcription, TFIIIA also stabilizes 5S rRNA until it is required for transcription. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00001)
857
- def self.rRNA_5S
858
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000652')
2121
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000643') then
2122
+ return true
859
2123
  end
860
-
861
- # A component of the large ribosomal subunit. (SO:ke)
862
- def self.rRNA_28S
863
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000653')
2124
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000644') then
2125
+ return true
864
2126
  end
865
-
866
- # An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product. (SO:ke)
867
- def self.ncRNA
868
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000655')
2127
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000645') then
2128
+ return true
869
2129
  end
870
-
871
- # A region of sequence containing one or more repeat units. (SO:ke)
872
- def self.repeat_region
873
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000657')
2130
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000646') then
2131
+ return true
874
2132
  end
875
-
876
- # A repeat that is located at dispersed sites in the genome. (SO:ke)
877
- def self.dispersed_repeat
878
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000658')
2133
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000649') then
2134
+ return true
879
2135
  end
880
-
881
- # An intron which is spliced by the spliceosome. (SO:ke)
882
- def self.spliceosomal_intron
883
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000662')
2136
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000650') then
2137
+ return true
884
2138
  end
885
-
886
- # The sequence of one or more nucleotides added between two adjacent nucleotides in the sequence. (SO:ke)
887
- def self.insertion
888
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000667')
2139
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000651') then
2140
+ return true
889
2141
  end
890
-
891
- # A match against an EST sequence. (SO:ke)
892
- def self.EST_match
893
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000668')
2142
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000652') then
2143
+ return true
894
2144
  end
895
-
896
- # An RNA synthesized on a DNA or RNA template by an RNA polymerase. (SO:ma)
897
- def self.transcript
898
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000673')
2145
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000653') then
2146
+ return true
899
2147
  end
900
-
901
- # A region of nucleotide sequence targeted by a nuclease enzyme. (SO:ma)
902
- def self.nuclease_sensitive_site
903
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000684')
2148
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000655') then
2149
+ return true
904
2150
  end
905
-
906
- # The space between two bases in a sequence which marks the position where a deletion has occurred. (SO:ke)
907
- def self.deletion_junction
908
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000687')
2151
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000657') then
2152
+ return true
909
2153
  end
910
-
911
- # A set of subregions selected from sequence contigs which when concatenated form a nonredundant linear sequence. (SO:ls)
912
- def self.golden_path
913
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000688')
2154
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000658') then
2155
+ return true
914
2156
  end
915
-
916
- # A match against cDNA sequence. (SO:ke)
917
- def self.cDNA_match
918
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000689')
2157
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000662') then
2158
+ return true
919
2159
  end
920
-
921
- # SNPs are single base pair positions in genomic DNA at which different sequence alternatives exist in normal individuals in some population(s), wherein the least frequent variant has an abundance of 1% or greater. (SO:cb)
922
- def self.SNP
923
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000694')
2160
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000667') then
2161
+ return true
924
2162
  end
925
-
926
- # A sequence used in experiment. (SO:ke)
927
- def self.reagent
928
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000695')
2163
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000668') then
2164
+ return true
929
2165
  end
930
-
931
- # A short oligonucleotide sequence, of length on the order of 10's of bases; either single or double stranded. (SO:ma)
932
- def self.oligo
933
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000696')
2166
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000673') then
2167
+ return true
934
2168
  end
935
-
936
- # A sequence_feature with an extent of zero. (SO:ke)
937
- def self.junction
938
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000699')
2169
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000684') then
2170
+ return true
939
2171
  end
940
-
941
- # A comment about the sequence. (SO:ke)
942
- def self.remark
943
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000700')
2172
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000687') then
2173
+ return true
944
2174
  end
945
-
946
- # A region of sequence where the validity of the base calling is questionable. (SO:ke)
947
- def self.possible_base_call_error
948
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000701')
2175
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000688') then
2176
+ return true
949
2177
  end
950
-
951
- # A region of sequence where there may have been an error in the assembly. (SO:ke)
952
- def self.possible_assembly_error
953
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000702')
2178
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000689') then
2179
+ return true
954
2180
  end
955
-
956
- # A region of sequence implicated in an experimental result. (SO:ke)
957
- def self.experimental_result_region
958
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000703')
2181
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000694') then
2182
+ return true
959
2183
  end
960
-
961
- # A region (or regions) that includes all of the sequence elements necessary to encode a functional transcript. A gene may include regulatory regions, transcribed regions and/or other functional sequence regions. (SO:immuno_workshop)
962
- def self.gene
963
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000704')
2184
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000695') then
2185
+ return true
964
2186
  end
965
-
966
- # Two or more adjcent copies of a region (of length greater than 1). (SO:ke)
967
- def self.tandem_repeat
968
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000705')
2187
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000696') then
2188
+ return true
969
2189
  end
970
-
971
- # The 3' splice site of the acceptor primary transcript. (SO:ke)
972
- def self.trans_splice_acceptor_site
973
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000706')
2190
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000699') then
2191
+ return true
974
2192
  end
975
-
976
- # A region of nucleotide sequence corresponding to a known motif. (SO:ke)
977
- def self.nucleotide_motif
978
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000714')
2193
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000700') then
2194
+ return true
979
2195
  end
980
-
981
- # A motif that is active in RNA sequence. (SO:ke)
982
- def self.RNA_motif
983
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000715')
2196
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000701') then
2197
+ return true
984
2198
  end
985
-
986
- # A nucleic acid sequence that when read as sequential triplets, has the potential of encoding a sequential string of amino acids. It need not contain the start or stop codon. (SGD:rb)
987
- def self.reading_frame
988
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000717')
2199
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000702') then
2200
+ return true
989
2201
  end
990
-
991
- # An ordered and oriented set of scaffolds based on somewhat weaker sets of inferential evidence such as one set of mate pair reads together with supporting evidence from ESTs or location of markers from SNP or microsatellite maps, or cytogenetic localization of contained markers. (FB:WG)
992
- def self.ultracontig
993
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000719')
2202
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000703') then
2203
+ return true
994
2204
  end
995
-
996
- # A region of a DNA molecule where transfer is initiated during the process of conjugation or mobilization. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
997
- def self.oriT
998
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000724')
2205
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000704') then
2206
+ return true
999
2207
  end
1000
-
1001
- # The transit_peptide is a short region at the N-terminus of the peptide that directs the protein to an organelle (chloroplast, mitochondrion, microbody or cyanelle). (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
1002
- def self.transit_peptide
1003
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000725')
2208
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000705') then
2209
+ return true
1004
2210
  end
1005
-
1006
- # A regulatory_region where more than 1 TF_binding_site together are regulatorily active. (SO:SG)
1007
- def self.CRM
1008
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000727')
2211
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000706') then
2212
+ return true
1009
2213
  end
1010
-
1011
- # A gap in the sequence of known length. The unknown bases are filled in with N's. (SO:ke)
1012
- def self.gap
1013
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000730')
2214
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000714') then
2215
+ return true
1014
2216
  end
1015
-
1016
- def self.gene_group_regulatory_region
1017
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000752')
2217
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000715') then
2218
+ return true
1018
2219
  end
1019
-
1020
- # The region of sequence that has been inserted and is being propagated by the clone. (SO:ke)
1021
- def self.clone_insert
1022
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000753')
2220
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000717') then
2221
+ return true
1023
2222
  end
1024
-
1025
- # A non functional descendent of an rRNA. (SO:ke)
1026
- def self.pseudogenic_rRNA
1027
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000777')
2223
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000719') then
2224
+ return true
1028
2225
  end
1029
-
1030
- # A non functional descendent of a tRNA. (SO:ke)
1031
- def self.pseudogenic_tRNA
1032
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000778')
2226
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000724') then
2227
+ return true
1033
2228
  end
1034
-
1035
- # A region of a chromosome. (SO:ke)
1036
- def self.chromosome_part
1037
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000830')
2229
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000725') then
2230
+ return true
1038
2231
  end
1039
-
1040
- # A region of a gene. (SO:ke)
1041
- def self.gene_member_region
1042
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000831')
2232
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000727') then
2233
+ return true
1043
2234
  end
1044
-
1045
- # A region of a transcript. (SO:ke)
1046
- def self.transcript_region
1047
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000833')
2235
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000730') then
2236
+ return true
1048
2237
  end
1049
-
1050
- # A region of a mature transcript. (SO:ke)
1051
- def self.mature_transcript_region
1052
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000834')
2238
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000752') then
2239
+ return true
1053
2240
  end
1054
-
1055
- # A part of a primary transcript. (SO:ke)
1056
- def self.primary_transcript_region
1057
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000835')
2241
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000753') then
2242
+ return true
1058
2243
  end
1059
-
1060
- # A region of an mRNA. (SO:cb)
1061
- def self.mRNA_region
1062
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000836')
2244
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000777') then
2245
+ return true
1063
2246
  end
1064
-
1065
- # A region of UTR. (SO:ke)
1066
- def self.UTR_region
1067
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000837')
2247
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000778') then
2248
+ return true
1068
2249
  end
1069
-
1070
- # Biological sequence region that can be assigned to a specific subsequence of a polypeptide. (SO:GAR, SO:ke)
1071
- def self.polypeptide_region
1072
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000839')
2250
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000830') then
2251
+ return true
1073
2252
  end
1074
-
1075
- # A region within an intron. (SO:ke)
1076
- def self.spliceosomal_intron_region
1077
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000841')
2253
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000831') then
2254
+ return true
1078
2255
  end
1079
-
1080
- def self.gene_component_region
1081
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000842')
2256
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000833') then
2257
+ return true
1082
2258
  end
1083
-
1084
- # A region of a CDS. (SO:cb)
1085
- def self.CDS_region
1086
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000851')
2259
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000834') then
2260
+ return true
1087
2261
  end
1088
-
1089
- # A region of an exon. (RSC:cb)
1090
- def self.exon_region
1091
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000852')
2262
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000835') then
2263
+ return true
1092
2264
  end
1093
-
1094
- # A large polynucleotide in Bacteria and Archaea, which functions as the small subunit of the ribosome. (SO:ke)
1095
- def self.rRNA_16S
1096
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001000')
2265
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000836') then
2266
+ return true
1097
2267
  end
1098
-
1099
- # A large polynucleotide in Bacteria and Archaea, which functions as the large subunit of the ribosome. (SO:ke)
1100
- def self.rRNA_23S
1101
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001001')
2268
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000837') then
2269
+ return true
1102
2270
  end
1103
-
1104
- # A large polynucleotide which functions as part of the large subunit of the ribosome in some eukaryotes. (RSC:cb)
1105
- def self.rRNA_25S
1106
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001002')
2271
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000839') then
2272
+ return true
1107
2273
  end
1108
-
1109
- # A variation that increases or decreases the copy number of a given region. (SO:ke)
1110
- def self.copy_number_variation
1111
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001019')
2274
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000841') then
2275
+ return true
1112
2276
  end
1113
-
1114
- # A nucleotide region with either intra-genome or intracellular moblity, of varying length, which often carry the information necessary for transfer and recombination with the host genome. (PMID:14681355)
1115
- def self.mobile_genetic_element
1116
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001037')
2277
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000842') then
2278
+ return true
1117
2279
  end
1118
-
1119
- # An MGE that is integrated into the host chromosome. (SO:ke)
1120
- def self.integrated_mobile_genetic_element
1121
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001039')
2280
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000851') then
2281
+ return true
1122
2282
  end
1123
-
1124
- # A regulatory_region that modulates the transcription of a gene or genes. (SO:regcreative)
1125
- def self.transcriptional_cis_regulatory_region
1126
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001055')
2283
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000852') then
2284
+ return true
1127
2285
  end
1128
-
1129
- # A regulatory_region that modulates splicing. (SO:ke)
1130
- def self.splicing_regulatory_region
1131
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001056')
2286
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001000') then
2287
+ return true
1132
2288
  end
1133
-
1134
- # A sequence_alteration is a sequence_feature whose extent is the deviation from another sequence. (SO:ke)
1135
- def self.sequence_alteration
1136
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001059')
2289
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001001') then
2290
+ return true
1137
2291
  end
1138
-
1139
- # An immature_peptide_region is the extent of the peptide after it has been translated and before any processing occurs. (EBIBS:GAR)
1140
- def self.immature_peptide_region
1141
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001063')
2292
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001002') then
2293
+ return true
1142
2294
  end
1143
-
1144
- # The maximal intersection of exon and UTR. (SO:ke)
1145
- def self.noncoding_region_of_exon
1146
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001214')
2295
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001019') then
2296
+ return true
1147
2297
  end
1148
-
1149
- # The region of an exon that encodes for protein sequence. (SO:ke)
1150
- def self.coding_region_of_exon
1151
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001215')
2298
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001037') then
2299
+ return true
1152
2300
  end
1153
-
1154
- # A region containing at least one unique origin of replication and a unique termination site. (ISBN:0716719207)
1155
- def self.replicon
1156
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001235')
2301
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001039') then
2302
+ return true
1157
2303
  end
1158
-
1159
- # A base is a sequence feature that corresponds to a single unit of a nucleotide polymer. (SO:ke)
1160
- def self.base
1161
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001236')
2304
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001055') then
2305
+ return true
1162
2306
  end
1163
-
1164
- # A region of the genome of known length that is composed by ordering and aligning two or more different regions. (SO:ke)
1165
- def self.assembly
1166
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001248')
2307
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001056') then
2308
+ return true
1167
2309
  end
1168
-
1169
- # A region which is intended for use in an experiment. (SO:cb)
1170
- def self.biomaterial_region
1171
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001409')
2310
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001059') then
2311
+ return true
1172
2312
  end
1173
-
1174
- # A region which is the result of some arbitrary experimental procedure. The procedure may be carried out with biological material or inside a computer. (SO:cb)
1175
- def self.experimental_feature
1176
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001410')
2313
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001063') then
2314
+ return true
1177
2315
  end
1178
-
1179
- # A region defined by its disposition to be involved in a biological process. (SO:cb)
1180
- def self.biological_region
1181
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001411')
2316
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001214') then
2317
+ return true
1182
2318
  end
1183
-
1184
- # A region that is defined according to its relations with other regions within the same sequence. (SO:cb)
1185
- def self.topologically_defined_region
1186
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001412')
2319
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001215') then
2320
+ return true
1187
2321
  end
1188
-
1189
- # Intronic 2 bp region bordering exon. A splice_site that adjacent_to exon and overlaps intron. (SO:cjm, SO:ke)
1190
- def self.cis_splice_site
1191
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001419')
2322
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001235') then
2323
+ return true
1192
2324
  end
1193
-
1194
- # Primary transcript region bordering trans-splice junction. (SO:ke)
1195
- def self.trans_splice_site
1196
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001420')
2325
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001236') then
2326
+ return true
1197
2327
  end
1198
-
1199
- # SNVs are single nucleotide positions in genomic DNA at which different sequence alternatives exist. (SO:bm)
1200
- def self.SNV
1201
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001483')
2328
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001248') then
2329
+ return true
1202
2330
  end
1203
-
1204
- # A region of peptide sequence used to target the polypeptide molecule to a specific organelle. (SO:ke)
1205
- def self.peptide_localization_signal
1206
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001527')
2331
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001409') then
2332
+ return true
1207
2333
  end
1208
-
1209
- # A kind of ribosome entry site, specific to Eukaryotic organisms that overlaps part of both 5' UTR and CDS sequence. (SO:ke)
1210
- def self.kozak_sequence
1211
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001647')
2334
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001410') then
2335
+ return true
1212
2336
  end
1213
-
1214
- # A binding site that, in the nucleotide molecule, interacts selectively and non-covalently with polypeptide residues. (SO:ke)
1215
- def self.nucleotide_to_protein_binding_site
1216
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001654')
2337
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001411') then
2338
+ return true
1217
2339
  end
1218
-
1219
- # A regulatory region that is involved in the control of the process of transcription. (SO:ke)
1220
- def self.transcription_regulatory_region
1221
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001679')
2340
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001412') then
2341
+ return true
1222
2342
  end
1223
-
1224
- # A sequence motif is a nucleotide or amino-acid sequence pattern that may have biological significance. (http://en.wikipedia.org/wiki/Sequence_motif)
1225
- def self.sequence_motif
1226
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001683')
2343
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001419') then
2344
+ return true
1227
2345
  end
1228
-
1229
- # A biological region implicated in inherited changes caused by mechanisms other than changes in the underlying DNA sequence. (http://en.wikipedia.org/wiki/Epigenetics, SO:ke)
1230
- def self.epigenetically_modified_region
1231
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001720')
2346
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001420') then
2347
+ return true
1232
2348
  end
1233
-
1234
- # An assembly region that has been sequenced from both ends resulting in a read_pair (mate_pair). (SO:ke)
1235
- def self.paired_end_fragment
1236
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001790')
2349
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001483') then
2350
+ return true
1237
2351
  end
1238
-
1239
- # A region of sequence that is involved in the control of a biological process. (SO:ke)
1240
- def self.regulatory_region
1241
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0005836')
2352
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001527') then
2353
+ return true
1242
2354
  end
1243
-
1244
- # A collection of related genes. (SO:ma)
1245
- def self.gene_group
1246
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0005855')
2355
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001647') then
2356
+ return true
1247
2357
  end
1248
-
1249
- # The cleaved_peptide_regon is the a region of peptide sequence that is cleaved during maturation. (EBIBS:GAR)
1250
- def self.cleaved_peptide_region
1251
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_0100011')
2358
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001654') then
2359
+ return true
1252
2360
  end
1253
-
1254
- # A sequence alteration where the length of the change in the variant is the same as that of the reference. (SO:ke)
1255
- def self.substitution
1256
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_1000002')
2361
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001679') then
2362
+ return true
1257
2363
  end
1258
-
1259
- # When no simple or well defined DNA mutation event describes the observed DNA change, the keyword \"complex\" should be used. Usually there are multiple equally plausible explanations for the change. (EBI:www.ebi.ac.uk/mutations/recommendations/mutevent.html)
1260
- def self.complex_substitution
1261
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_1000005')
2364
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001683') then
2365
+ return true
1262
2366
  end
1263
-
1264
- # A single nucleotide change which has occurred at the same position of a corresponding nucleotide in a reference sequence. (SO:immuno_workshop)
1265
- def self.point_mutation
1266
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_1000008')
2367
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001720') then
2368
+ return true
1267
2369
  end
1268
-
1269
- # A continuous nucleotide sequence is inverted in the same position. (EBI:www.ebi.ac.uk/mutations/recommendations/mutevent.html)
1270
- def self.inversion
1271
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_1000036')
2370
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001790') then
2371
+ return true
2372
+ end
2373
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0005836') then
2374
+ return true
2375
+ end
2376
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0005855') then
2377
+ return true
2378
+ end
2379
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0100011') then
2380
+ return true
2381
+ end
2382
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_1000002') then
2383
+ return true
2384
+ end
2385
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_1000005') then
2386
+ return true
2387
+ end
2388
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_1000008') then
2389
+ return true
1272
2390
  end
1273
-
1274
- # A group of genes, whether linked as a cluster or not, that respond to a common regulatory signal. (ISBN:0198506732)
1275
- def self.regulon
1276
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_1001284')
1277
- end
1278
-
1279
- # The sequence referred to by an entry in a databank such as Genbank or SwissProt. (SO:ke)
1280
- def self.databank_entry
1281
- RDF::URI.new('http://purl.obolibrary.org/obo/SO_2000061')
1282
- end
1283
-
1284
- # Determines whether the given URI is an object property.
1285
- #
1286
- # +uri+:: URI that is tested for being an object property
1287
- def self.is_object_property?(uri)
1288
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:adjacent_to')
1289
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:has_integral_part')
1290
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:has_part')
1291
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:integral_part_of')
1292
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:non_functional_homolog_of')
1293
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:partial_evidence_for_feature')
1294
- false
1295
- end
1296
-
1297
- # Determines whether the given URI is a datatype property.
1298
- #
1299
- # +uri+:: URI that is tested for being a datatype property
1300
- def self.is_datatype_property?(uri)
1301
- false
1302
- end
1303
-
1304
- # Determines whether the given URI is a class.
1305
- #
1306
- # +uri+:: URI that is tested for being a class
1307
- def self.is_class?(uri)
1308
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000000')
1309
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000001')
1310
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000004')
1311
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000005')
1312
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000006')
1313
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000007')
1314
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000013')
1315
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000038')
1316
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000039')
1317
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000050')
1318
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000057')
1319
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000059')
1320
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000101')
1321
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000102')
1322
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000103')
1323
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000104')
1324
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000109')
1325
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000110')
1326
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000112')
1327
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000113')
1328
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000114')
1329
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000120')
1330
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000139')
1331
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000140')
1332
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000141')
1333
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000143')
1334
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000147')
1335
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000148')
1336
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000149')
1337
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000150')
1338
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000151')
1339
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000159')
1340
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000161')
1341
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000162')
1342
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000163')
1343
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000164')
1344
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000165')
1345
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000167')
1346
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000177')
1347
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000178')
1348
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000179')
1349
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000181')
1350
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000183')
1351
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000185')
1352
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000187')
1353
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000188')
1354
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000193')
1355
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000195')
1356
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000196')
1357
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000197')
1358
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000198')
1359
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000200')
1360
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000203')
1361
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000204')
1362
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000205')
1363
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000209')
1364
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000233')
1365
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000234')
1366
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000235')
1367
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000236')
1368
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000239')
1369
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000252')
1370
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000253')
1371
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000274')
1372
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000275')
1373
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000276')
1374
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000289')
1375
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000294')
1376
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000296')
1377
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000303')
1378
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000305')
1379
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000306')
1380
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000307')
1381
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000314')
1382
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000315')
1383
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000316')
1384
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000318')
1385
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000319')
1386
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000324')
1387
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000325')
1388
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000326')
1389
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000330')
1390
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000331')
1391
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000332')
1392
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000333')
1393
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000334')
1394
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000336')
1395
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000337')
1396
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000340')
1397
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000341')
1398
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000343')
1399
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000344')
1400
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000345')
1401
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000347')
1402
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000349')
1403
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000353')
1404
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000360')
1405
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000366')
1406
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000368')
1407
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000370')
1408
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000372')
1409
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000374')
1410
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000375')
1411
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000380')
1412
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000385')
1413
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000386')
1414
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000390')
1415
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000391')
1416
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000392')
1417
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000393')
1418
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000394')
1419
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000395')
1420
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000396')
1421
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000397')
1422
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000398')
1423
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000399')
1424
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000403')
1425
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000404')
1426
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000405')
1427
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000407')
1428
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000409')
1429
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000410')
1430
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000412')
1431
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000413')
1432
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000418')
1433
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000419')
1434
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000436')
1435
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000441')
1436
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000442')
1437
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000454')
1438
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000462')
1439
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000464')
1440
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000468')
1441
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000472')
1442
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000474')
1443
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000483')
1444
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000484')
1445
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000486')
1446
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000499')
1447
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000502')
1448
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000551')
1449
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000553')
1450
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000577')
1451
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000581')
1452
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000587')
1453
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000588')
1454
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000590')
1455
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000593')
1456
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000602')
1457
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000603')
1458
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000605')
1459
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000610')
1460
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000611')
1461
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000612')
1462
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000616')
1463
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000624')
1464
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000625')
1465
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000627')
1466
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000628')
1467
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000643')
1468
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000644')
1469
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000645')
1470
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000646')
1471
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000649')
1472
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000650')
1473
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000651')
1474
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000652')
1475
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000653')
1476
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000655')
1477
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000657')
1478
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000658')
1479
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000662')
1480
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000667')
1481
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000668')
1482
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000673')
1483
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000684')
1484
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000687')
1485
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000688')
1486
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000689')
1487
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000694')
1488
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000695')
1489
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000696')
1490
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000699')
1491
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000700')
1492
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000701')
1493
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000702')
1494
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000703')
1495
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000704')
1496
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000705')
1497
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000706')
1498
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000714')
1499
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000715')
1500
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000717')
1501
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000719')
1502
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000724')
1503
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000725')
1504
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000727')
1505
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000730')
1506
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000752')
1507
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000753')
1508
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000777')
1509
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000778')
1510
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000830')
1511
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000831')
1512
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000833')
1513
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000834')
1514
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000835')
1515
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000836')
1516
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000837')
1517
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000839')
1518
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000841')
1519
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000842')
1520
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000851')
1521
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000852')
1522
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001000')
1523
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001001')
1524
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001002')
1525
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001019')
1526
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001037')
1527
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001039')
1528
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001055')
1529
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001056')
1530
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001059')
1531
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001063')
1532
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001214')
1533
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001215')
1534
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001235')
1535
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001236')
1536
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001248')
1537
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001409')
1538
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001410')
1539
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001411')
1540
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001412')
1541
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001419')
1542
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001420')
1543
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001483')
1544
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001527')
1545
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001647')
1546
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001654')
1547
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001679')
1548
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001683')
1549
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001720')
1550
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001790')
1551
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0005836')
1552
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0005855')
1553
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_0100011')
1554
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_1000002')
1555
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_1000005')
1556
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_1000008')
1557
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_1000036')
1558
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_1001284')
1559
- return true if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_2000061')
1560
- false
2391
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_1000036') then
2392
+ return true
1561
2393
  end
2394
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_1001284') then
2395
+ return true
2396
+ end
2397
+ if uri == RDF::URI.new('http://purl.obolibrary.org/obo/SO_2000061') then
2398
+ return true
2399
+ end
2400
+ return false
2401
+ end
1562
2402
 
1563
- end
2403
+ # Determines whether the given URI is a named individual.
2404
+ #
2405
+ # +uri+:: URI that is tested for being a named individual
2406
+ def self.is_named_individual?(uri)
2407
+ return false
2408
+ end
2409
+
2410
+ # Returns only those URIs that fall under a designated parent URI.
2411
+ #
2412
+ # +uris+:: Set of URIs that are tested whether they have the given parent URI.
2413
+ # +parent+:: Parent URI.
2414
+ def self.with_parent(uris, parent)
2415
+ return uris.select { |uri| has_parent?(uri, parent) }
2416
+ end
1564
2417
 
2418
+ # Recursively tries to determine the parent for a given URI.
2419
+ #
2420
+ # +uri+:: URI that is tested for whether it has the given parent URI.
2421
+ # +parent+:: Parent URI.
2422
+ def self.has_parent?(uri, parent)
2423
+ if @@parent_properties.has_key?(uri) then
2424
+ if @@parent_properties[uri] == parent then
2425
+ return true
2426
+ end
2427
+ return has_parent?(@@parent_properties[uri], parent)
2428
+ end
2429
+ return false
2430
+ end
2431
+
2432
+ private
2433
+ @@parent_properties = { RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:complete_evidence_for_feature') => RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:evidence_for_feature') , RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:has_integral_part') => RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:has_part') , RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:homologous_to') => RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:similar_to') , RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:integral_part_of') => RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:part_of') , RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:member_of') => RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:part_of') , RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:non_functional_homolog_of') => RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:homologous_to') , RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:orthologous_to') => RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:homologous_to') , RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:paralogous_to') => RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:homologous_to') , RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:partial_evidence_for_feature') => RDF::URI.new('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:evidence_for_feature') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000001') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000110') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000004') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000195') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000005') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000705') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000006') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000695') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000057') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000752') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000059') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001654') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000101') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001039') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000102') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000347') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000112') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000441') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000113') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001039') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000114') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000306') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000120') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000185') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000139') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000836') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000143') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001410') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000147') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000833') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000151') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000695') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000159') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001411') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000161') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000306') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000162') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000835') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000163') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001419') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000164') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001419') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000165') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000727') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000167') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001055') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000177') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000347') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000178') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0005855') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000181') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000347') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000183') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000842') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000185') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000673') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000188') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000835') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000193') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000412') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000195') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000147') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000198') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000147') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000200') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000195') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000203') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000836') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000204') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000203') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000205') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000203') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000209') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000483') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000234') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000233') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000235') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001679') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000236') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000717') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000239') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001412') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000289') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000005') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000294') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000657') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000303') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000835') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000305') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001720') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000306') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000305') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000307') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001411') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000314') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000657') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000315') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000835') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000316') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000836') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000318') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000360') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000319') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000360') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000324') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000696') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000325') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000209') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000326') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000324') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000330') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0001410') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000331') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000324') , RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000332') => RDF::URI.new('http://purl.obolibrary.org/obo/SO_0000330') , 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2434
+
2435
+ end
1565
2436
 
1566
2437
  end