bio 1.3.1 → 1.4.0

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Files changed (303) hide show
  1. data/ChangeLog +2105 -3728
  2. data/KNOWN_ISSUES.rdoc +35 -3
  3. data/README.rdoc +8 -2
  4. data/RELEASE_NOTES.rdoc +166 -0
  5. data/bin/bioruby +4 -1
  6. data/bioruby.gemspec +146 -1
  7. data/bioruby.gemspec.erb +3 -1
  8. data/doc/ChangeLog-before-1.3.1 +3961 -0
  9. data/doc/Tutorial.rd +154 -22
  10. data/doc/Tutorial.rd.html +125 -68
  11. data/lib/bio.rb +21 -6
  12. data/lib/bio/appl/bl2seq/report.rb +11 -202
  13. data/lib/bio/appl/blast/format0.rb +0 -193
  14. data/lib/bio/appl/blast/report.rb +2 -147
  15. data/lib/bio/appl/blast/wublast.rb +0 -208
  16. data/lib/bio/appl/fasta.rb +4 -19
  17. data/lib/bio/appl/fasta/format10.rb +0 -14
  18. data/lib/bio/appl/genscan/report.rb +0 -176
  19. data/lib/bio/appl/hmmer.rb +1 -15
  20. data/lib/bio/appl/hmmer/report.rb +0 -100
  21. data/lib/bio/appl/meme/mast.rb +156 -0
  22. data/lib/bio/appl/meme/mast/report.rb +91 -0
  23. data/lib/bio/appl/meme/motif.rb +48 -0
  24. data/lib/bio/appl/psort.rb +0 -111
  25. data/lib/bio/appl/psort/report.rb +1 -45
  26. data/lib/bio/appl/pts1.rb +2 -4
  27. data/lib/bio/appl/sosui/report.rb +5 -54
  28. data/lib/bio/appl/targetp/report.rb +1 -104
  29. data/lib/bio/appl/tmhmm/report.rb +0 -36
  30. data/lib/bio/command.rb +94 -10
  31. data/lib/bio/data/aa.rb +1 -77
  32. data/lib/bio/data/codontable.rb +1 -95
  33. data/lib/bio/data/na.rb +1 -26
  34. data/lib/bio/db/aaindex.rb +1 -38
  35. data/lib/bio/db/fasta.rb +1 -134
  36. data/lib/bio/db/fasta/format_qual.rb +204 -0
  37. data/lib/bio/db/fasta/qual.rb +102 -0
  38. data/lib/bio/db/fastq.rb +645 -0
  39. data/lib/bio/db/fastq/fastq_to_biosequence.rb +40 -0
  40. data/lib/bio/db/fastq/format_fastq.rb +175 -0
  41. data/lib/bio/db/genbank/genbank.rb +1 -86
  42. data/lib/bio/db/gff.rb +0 -17
  43. data/lib/bio/db/go.rb +4 -72
  44. data/lib/bio/db/kegg/common.rb +112 -0
  45. data/lib/bio/db/kegg/compound.rb +29 -20
  46. data/lib/bio/db/kegg/drug.rb +74 -34
  47. data/lib/bio/db/kegg/enzyme.rb +26 -5
  48. data/lib/bio/db/kegg/genes.rb +128 -15
  49. data/lib/bio/db/kegg/genome.rb +3 -41
  50. data/lib/bio/db/kegg/glycan.rb +19 -24
  51. data/lib/bio/db/kegg/orthology.rb +16 -56
  52. data/lib/bio/db/kegg/reaction.rb +81 -28
  53. data/lib/bio/db/kegg/taxonomy.rb +1 -52
  54. data/lib/bio/db/litdb.rb +1 -16
  55. data/lib/bio/db/phyloxml/phyloxml.xsd +582 -0
  56. data/lib/bio/db/phyloxml/phyloxml_elements.rb +1174 -0
  57. data/lib/bio/db/phyloxml/phyloxml_parser.rb +954 -0
  58. data/lib/bio/db/phyloxml/phyloxml_writer.rb +228 -0
  59. data/lib/bio/db/prosite.rb +2 -95
  60. data/lib/bio/db/rebase.rb +5 -6
  61. data/lib/bio/db/sanger_chromatogram/abif.rb +120 -0
  62. data/lib/bio/db/sanger_chromatogram/chromatogram.rb +133 -0
  63. data/lib/bio/db/sanger_chromatogram/chromatogram_to_biosequence.rb +32 -0
  64. data/lib/bio/db/sanger_chromatogram/scf.rb +210 -0
  65. data/lib/bio/io/das.rb +0 -44
  66. data/lib/bio/io/ddbjxml.rb +1 -181
  67. data/lib/bio/io/flatfile.rb +1 -7
  68. data/lib/bio/io/flatfile/autodetection.rb +6 -0
  69. data/lib/bio/io/keggapi.rb +0 -442
  70. data/lib/bio/io/ncbirest.rb +130 -132
  71. data/lib/bio/io/ncbisoap.rb +2 -1
  72. data/lib/bio/io/pubmed.rb +0 -88
  73. data/lib/bio/location.rb +0 -73
  74. data/lib/bio/pathway.rb +0 -171
  75. data/lib/bio/sequence.rb +18 -1
  76. data/lib/bio/sequence/adapter.rb +3 -0
  77. data/lib/bio/sequence/format.rb +16 -0
  78. data/lib/bio/sequence/quality_score.rb +205 -0
  79. data/lib/bio/tree.rb +70 -5
  80. data/lib/bio/util/restriction_enzyme/single_strand.rb +3 -2
  81. data/lib/bio/util/sirna.rb +1 -23
  82. data/lib/bio/version.rb +1 -1
  83. data/sample/demo_aaindex.rb +67 -0
  84. data/sample/demo_aminoacid.rb +101 -0
  85. data/sample/demo_bl2seq_report.rb +220 -0
  86. data/sample/demo_blast_report.rb +285 -0
  87. data/sample/demo_codontable.rb +119 -0
  88. data/sample/demo_das.rb +105 -0
  89. data/sample/demo_ddbjxml.rb +212 -0
  90. data/sample/demo_fasta_remote.rb +51 -0
  91. data/sample/demo_fastaformat.rb +105 -0
  92. data/sample/demo_genbank.rb +132 -0
  93. data/sample/demo_genscan_report.rb +202 -0
  94. data/sample/demo_gff1.rb +49 -0
  95. data/sample/demo_go.rb +98 -0
  96. data/sample/demo_hmmer_report.rb +149 -0
  97. data/sample/demo_kegg_compound.rb +57 -0
  98. data/sample/demo_kegg_drug.rb +65 -0
  99. data/sample/demo_kegg_genome.rb +74 -0
  100. data/sample/demo_kegg_glycan.rb +72 -0
  101. data/sample/demo_kegg_orthology.rb +62 -0
  102. data/sample/demo_kegg_reaction.rb +66 -0
  103. data/sample/demo_kegg_taxonomy.rb +92 -0
  104. data/sample/demo_keggapi.rb +502 -0
  105. data/sample/demo_litdb.rb +42 -0
  106. data/sample/demo_locations.rb +99 -0
  107. data/sample/demo_ncbi_rest.rb +130 -0
  108. data/sample/demo_nucleicacid.rb +49 -0
  109. data/sample/demo_pathway.rb +196 -0
  110. data/sample/demo_prosite.rb +120 -0
  111. data/sample/demo_psort.rb +138 -0
  112. data/sample/demo_psort_report.rb +70 -0
  113. data/sample/demo_pubmed.rb +118 -0
  114. data/sample/demo_sirna.rb +63 -0
  115. data/sample/demo_sosui_report.rb +89 -0
  116. data/sample/demo_targetp_report.rb +135 -0
  117. data/sample/demo_tmhmm_report.rb +68 -0
  118. data/sample/pmfetch.rb +13 -4
  119. data/sample/pmsearch.rb +15 -4
  120. data/sample/test_phyloxml_big.rb +205 -0
  121. data/test/bioruby_test_helper.rb +61 -0
  122. data/test/data/KEGG/1.1.1.1.enzyme +935 -0
  123. data/test/data/KEGG/C00025.compound +102 -0
  124. data/test/data/KEGG/D00063.drug +104 -0
  125. data/test/data/KEGG/G00024.glycan +47 -0
  126. data/test/data/KEGG/G01366.glycan +18 -0
  127. data/test/data/KEGG/K02338.orthology +902 -0
  128. data/test/data/KEGG/R00006.reaction +14 -0
  129. data/test/data/fastq/README.txt +109 -0
  130. data/test/data/fastq/error_diff_ids.fastq +20 -0
  131. data/test/data/fastq/error_double_qual.fastq +22 -0
  132. data/test/data/fastq/error_double_seq.fastq +22 -0
  133. data/test/data/fastq/error_long_qual.fastq +20 -0
  134. data/test/data/fastq/error_no_qual.fastq +20 -0
  135. data/test/data/fastq/error_qual_del.fastq +20 -0
  136. data/test/data/fastq/error_qual_escape.fastq +20 -0
  137. data/test/data/fastq/error_qual_null.fastq +0 -0
  138. data/test/data/fastq/error_qual_space.fastq +21 -0
  139. data/test/data/fastq/error_qual_tab.fastq +21 -0
  140. data/test/data/fastq/error_qual_unit_sep.fastq +20 -0
  141. data/test/data/fastq/error_qual_vtab.fastq +20 -0
  142. data/test/data/fastq/error_short_qual.fastq +20 -0
  143. data/test/data/fastq/error_spaces.fastq +20 -0
  144. data/test/data/fastq/error_tabs.fastq +21 -0
  145. data/test/data/fastq/error_trunc_at_plus.fastq +19 -0
  146. data/test/data/fastq/error_trunc_at_qual.fastq +19 -0
  147. data/test/data/fastq/error_trunc_at_seq.fastq +18 -0
  148. data/test/data/fastq/error_trunc_in_plus.fastq +19 -0
  149. data/test/data/fastq/error_trunc_in_qual.fastq +20 -0
  150. data/test/data/fastq/error_trunc_in_seq.fastq +18 -0
  151. data/test/data/fastq/error_trunc_in_title.fastq +17 -0
  152. data/test/data/fastq/illumina_full_range_as_illumina.fastq +8 -0
  153. data/test/data/fastq/illumina_full_range_as_sanger.fastq +8 -0
  154. data/test/data/fastq/illumina_full_range_as_solexa.fastq +8 -0
  155. data/test/data/fastq/illumina_full_range_original_illumina.fastq +8 -0
  156. data/test/data/fastq/longreads_as_illumina.fastq +40 -0
  157. data/test/data/fastq/longreads_as_sanger.fastq +40 -0
  158. data/test/data/fastq/longreads_as_solexa.fastq +40 -0
  159. data/test/data/fastq/longreads_original_sanger.fastq +120 -0
  160. data/test/data/fastq/misc_dna_as_illumina.fastq +16 -0
  161. data/test/data/fastq/misc_dna_as_sanger.fastq +16 -0
  162. data/test/data/fastq/misc_dna_as_solexa.fastq +16 -0
  163. data/test/data/fastq/misc_dna_original_sanger.fastq +16 -0
  164. data/test/data/fastq/misc_rna_as_illumina.fastq +16 -0
  165. data/test/data/fastq/misc_rna_as_sanger.fastq +16 -0
  166. data/test/data/fastq/misc_rna_as_solexa.fastq +16 -0
  167. data/test/data/fastq/misc_rna_original_sanger.fastq +16 -0
  168. data/test/data/fastq/sanger_full_range_as_illumina.fastq +8 -0
  169. data/test/data/fastq/sanger_full_range_as_sanger.fastq +8 -0
  170. data/test/data/fastq/sanger_full_range_as_solexa.fastq +8 -0
  171. data/test/data/fastq/sanger_full_range_original_sanger.fastq +8 -0
  172. data/test/data/fastq/solexa_full_range_as_illumina.fastq +8 -0
  173. data/test/data/fastq/solexa_full_range_as_sanger.fastq +8 -0
  174. data/test/data/fastq/solexa_full_range_as_solexa.fastq +8 -0
  175. data/test/data/fastq/solexa_full_range_original_solexa.fastq +8 -0
  176. data/test/data/fastq/wrapping_as_illumina.fastq +12 -0
  177. data/test/data/fastq/wrapping_as_sanger.fastq +12 -0
  178. data/test/data/fastq/wrapping_as_solexa.fastq +12 -0
  179. data/test/data/fastq/wrapping_original_sanger.fastq +24 -0
  180. data/test/data/meme/db +0 -0
  181. data/test/data/meme/mast +0 -0
  182. data/test/data/meme/mast.out +13 -0
  183. data/test/data/meme/meme.out +3 -0
  184. data/test/data/phyloxml/apaf.xml +666 -0
  185. data/test/data/phyloxml/bcl_2.xml +2097 -0
  186. data/test/data/phyloxml/made_up.xml +144 -0
  187. data/test/data/phyloxml/ncbi_taxonomy_mollusca_short.xml +65 -0
  188. data/test/data/phyloxml/phyloxml_examples.xml +415 -0
  189. data/test/data/sanger_chromatogram/test_chromatogram_abif.ab1 +0 -0
  190. data/test/data/sanger_chromatogram/test_chromatogram_scf_v2.scf +0 -0
  191. data/test/data/sanger_chromatogram/test_chromatogram_scf_v3.scf +0 -0
  192. data/test/functional/bio/appl/test_pts1.rb +7 -5
  193. data/test/functional/bio/io/test_ensembl.rb +4 -3
  194. data/test/functional/bio/io/test_pubmed.rb +9 -3
  195. data/test/functional/bio/io/test_soapwsdl.rb +5 -4
  196. data/test/functional/bio/io/test_togows.rb +5 -4
  197. data/test/functional/bio/sequence/test_output_embl.rb +6 -4
  198. data/test/functional/bio/test_command.rb +54 -5
  199. data/test/runner.rb +5 -3
  200. data/test/unit/bio/appl/bl2seq/test_report.rb +5 -4
  201. data/test/unit/bio/appl/blast/test_ncbioptions.rb +4 -2
  202. data/test/unit/bio/appl/blast/test_report.rb +5 -4
  203. data/test/unit/bio/appl/blast/test_rpsblast.rb +5 -4
  204. data/test/unit/bio/appl/gcg/test_msf.rb +5 -5
  205. data/test/unit/bio/appl/genscan/test_report.rb +8 -9
  206. data/test/unit/bio/appl/hmmer/test_report.rb +5 -4
  207. data/test/unit/bio/appl/iprscan/test_report.rb +6 -5
  208. data/test/unit/bio/appl/mafft/test_report.rb +6 -5
  209. data/test/unit/bio/appl/meme/mast/test_report.rb +46 -0
  210. data/test/unit/bio/appl/meme/test_mast.rb +103 -0
  211. data/test/unit/bio/appl/meme/test_motif.rb +38 -0
  212. data/test/unit/bio/appl/paml/codeml/test_rates.rb +5 -4
  213. data/test/unit/bio/appl/paml/codeml/test_report.rb +5 -4
  214. data/test/unit/bio/appl/paml/test_codeml.rb +5 -4
  215. data/test/unit/bio/appl/sim4/test_report.rb +5 -4
  216. data/test/unit/bio/appl/sosui/test_report.rb +6 -5
  217. data/test/unit/bio/appl/targetp/test_report.rb +5 -3
  218. data/test/unit/bio/appl/test_blast.rb +5 -4
  219. data/test/unit/bio/appl/test_fasta.rb +4 -2
  220. data/test/unit/bio/appl/test_pts1.rb +4 -2
  221. data/test/unit/bio/appl/tmhmm/test_report.rb +6 -5
  222. data/test/unit/bio/data/test_aa.rb +5 -3
  223. data/test/unit/bio/data/test_codontable.rb +5 -4
  224. data/test/unit/bio/data/test_na.rb +5 -3
  225. data/test/unit/bio/db/biosql/tc_biosql.rb +5 -1
  226. data/test/unit/bio/db/embl/test_common.rb +4 -2
  227. data/test/unit/bio/db/embl/test_embl.rb +6 -6
  228. data/test/unit/bio/db/embl/test_embl_rel89.rb +6 -6
  229. data/test/unit/bio/db/embl/test_embl_to_bioseq.rb +7 -8
  230. data/test/unit/bio/db/embl/test_sptr.rb +6 -8
  231. data/test/unit/bio/db/embl/test_uniprot.rb +6 -5
  232. data/test/unit/bio/db/fasta/test_format_qual.rb +346 -0
  233. data/test/unit/bio/db/kegg/test_compound.rb +146 -0
  234. data/test/unit/bio/db/kegg/test_drug.rb +194 -0
  235. data/test/unit/bio/db/kegg/test_enzyme.rb +241 -0
  236. data/test/unit/bio/db/kegg/test_genes.rb +32 -4
  237. data/test/unit/bio/db/kegg/test_glycan.rb +260 -0
  238. data/test/unit/bio/db/kegg/test_orthology.rb +50 -0
  239. data/test/unit/bio/db/kegg/test_reaction.rb +96 -0
  240. data/test/unit/bio/db/pdb/test_pdb.rb +4 -2
  241. data/test/unit/bio/db/sanger_chromatogram/test_abif.rb +76 -0
  242. data/test/unit/bio/db/sanger_chromatogram/test_scf.rb +98 -0
  243. data/test/unit/bio/db/test_aaindex.rb +6 -6
  244. data/test/unit/bio/db/test_fasta.rb +5 -46
  245. data/test/unit/bio/db/test_fastq.rb +829 -0
  246. data/test/unit/bio/db/test_gff.rb +4 -2
  247. data/test/unit/bio/db/test_lasergene.rb +7 -5
  248. data/test/unit/bio/db/test_medline.rb +4 -2
  249. data/test/unit/bio/db/test_newick.rb +6 -6
  250. data/test/unit/bio/db/test_nexus.rb +4 -2
  251. data/test/unit/bio/db/test_phyloxml.rb +769 -0
  252. data/test/unit/bio/db/test_phyloxml_writer.rb +328 -0
  253. data/test/unit/bio/db/test_prosite.rb +6 -5
  254. data/test/unit/bio/db/test_qual.rb +63 -0
  255. data/test/unit/bio/db/test_rebase.rb +5 -3
  256. data/test/unit/bio/db/test_soft.rb +7 -6
  257. data/test/unit/bio/io/flatfile/test_autodetection.rb +6 -7
  258. data/test/unit/bio/io/flatfile/test_buffer.rb +6 -5
  259. data/test/unit/bio/io/flatfile/test_splitter.rb +4 -4
  260. data/test/unit/bio/io/test_ddbjxml.rb +4 -3
  261. data/test/unit/bio/io/test_ensembl.rb +5 -3
  262. data/test/unit/bio/io/test_fastacmd.rb +4 -3
  263. data/test/unit/bio/io/test_flatfile.rb +6 -5
  264. data/test/unit/bio/io/test_soapwsdl.rb +4 -3
  265. data/test/unit/bio/io/test_togows.rb +4 -2
  266. data/test/unit/bio/sequence/test_aa.rb +5 -3
  267. data/test/unit/bio/sequence/test_common.rb +4 -2
  268. data/test/unit/bio/sequence/test_compat.rb +4 -2
  269. data/test/unit/bio/sequence/test_dblink.rb +5 -3
  270. data/test/unit/bio/sequence/test_na.rb +4 -2
  271. data/test/unit/bio/sequence/test_quality_score.rb +330 -0
  272. data/test/unit/bio/shell/plugin/test_seq.rb +5 -3
  273. data/test/unit/bio/test_alignment.rb +5 -3
  274. data/test/unit/bio/test_command.rb +4 -3
  275. data/test/unit/bio/test_db.rb +5 -3
  276. data/test/unit/bio/test_feature.rb +4 -2
  277. data/test/unit/bio/test_location.rb +4 -2
  278. data/test/unit/bio/test_map.rb +5 -3
  279. data/test/unit/bio/test_pathway.rb +4 -2
  280. data/test/unit/bio/test_reference.rb +4 -2
  281. data/test/unit/bio/test_sequence.rb +5 -3
  282. data/test/unit/bio/test_shell.rb +5 -3
  283. data/test/unit/bio/test_tree.rb +6 -6
  284. data/test/unit/bio/util/restriction_enzyme/analysis/test_calculated_cuts.rb +4 -2
  285. data/test/unit/bio/util/restriction_enzyme/analysis/test_cut_ranges.rb +4 -2
  286. data/test/unit/bio/util/restriction_enzyme/analysis/test_sequence_range.rb +4 -2
  287. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_aligned_strands.rb +4 -2
  288. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_location_pair.rb +4 -2
  289. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_location_pair_in_enzyme_notation.rb +4 -2
  290. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_locations.rb +4 -2
  291. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_locations_in_enzyme_notation.rb +4 -2
  292. data/test/unit/bio/util/restriction_enzyme/single_strand/test_cut_locations_in_enzyme_notation.rb +4 -2
  293. data/test/unit/bio/util/restriction_enzyme/test_analysis.rb +4 -2
  294. data/test/unit/bio/util/restriction_enzyme/test_cut_symbol.rb +4 -2
  295. data/test/unit/bio/util/restriction_enzyme/test_double_stranded.rb +4 -2
  296. data/test/unit/bio/util/restriction_enzyme/test_single_strand.rb +17 -13
  297. data/test/unit/bio/util/restriction_enzyme/test_single_strand_complement.rb +17 -13
  298. data/test/unit/bio/util/restriction_enzyme/test_string_formatting.rb +4 -2
  299. data/test/unit/bio/util/test_color_scheme.rb +5 -3
  300. data/test/unit/bio/util/test_contingency_table.rb +5 -3
  301. data/test/unit/bio/util/test_restriction_enzyme.rb +4 -2
  302. data/test/unit/bio/util/test_sirna.rb +6 -4
  303. metadata +147 -2
@@ -0,0 +1,16 @@
1
+ @FAKE0007 Original version has lower case unambiguous DNA with PHRED scores from 0 to 40 inclusive (in that order)
2
+ ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTA
3
+ +
4
+ !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHI
5
+ @FAKE0008 Original version has mixed case unambiguous DNA with PHRED scores from 0 to 40 inclusive (in that order)
6
+ gTcatAGcgTcatAGcgTcatAGcgTcatAGcgTcatAGcg
7
+ +
8
+ !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHI
9
+ @FAKE0009 Original version has lower case unambiguous DNA with PHRED scores from 0 to 40 inclusive (in that order)
10
+ tcagtcagtcagtcagtcagtcagtcagtcagtcagtcagt
11
+ +
12
+ !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHI
13
+ @FAKE0010 Original version has mixed case ambiguous DNA and PHRED scores of 40, 30, 20, 10 (cycled)
14
+ gatcrywsmkhbvdnGATCRYWSMKHBVDN
15
+ +
16
+ I?5+I?5+I?5+I?5+I?5+I?5+I?5+I?
@@ -0,0 +1,16 @@
1
+ @FAKE0011 Original version has lower case unambiguous RNA with PHRED scores from 0 to 40 inclusive (in that order)
2
+ ACGUACGUACGUACGUACGUACGUACGUACGUACGUACGUA
3
+ +
4
+ @ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]^_`abcdefgh
5
+ @FAKE0012 Original version has mixed case unambiguous RNA with PHRED scores from 0 to 40 inclusive (in that order)
6
+ gUcauAGcgUcauAGcgUcauAGcgUcauAGcgUcauAGcg
7
+ +
8
+ @ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]^_`abcdefgh
9
+ @FAKE0013 Original version has lower case unambiguous RNA with PHRED scores from 0 to 40 inclusive (in that order)
10
+ ucagucagucagucagucagucagucagucagucagucagu
11
+ +
12
+ @ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]^_`abcdefgh
13
+ @FAKE0014 Original version has mixed case ambiguous RNA with PHRED scores from 35 to 40 inclusive (cycled)
14
+ gaucrywsmkhbvdnGAUCRYWSMKHBVDN
15
+ +
16
+ cdefghcdefghcdefghcdefghcdefgh
@@ -0,0 +1,16 @@
1
+ @FAKE0011 Original version has lower case unambiguous RNA with PHRED scores from 0 to 40 inclusive (in that order)
2
+ ACGUACGUACGUACGUACGUACGUACGUACGUACGUACGUA
3
+ +
4
+ !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHI
5
+ @FAKE0012 Original version has mixed case unambiguous RNA with PHRED scores from 0 to 40 inclusive (in that order)
6
+ gUcauAGcgUcauAGcgUcauAGcgUcauAGcgUcauAGcg
7
+ +
8
+ !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHI
9
+ @FAKE0013 Original version has lower case unambiguous RNA with PHRED scores from 0 to 40 inclusive (in that order)
10
+ ucagucagucagucagucagucagucagucagucagucagu
11
+ +
12
+ !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHI
13
+ @FAKE0014 Original version has mixed case ambiguous RNA with PHRED scores from 35 to 40 inclusive (cycled)
14
+ gaucrywsmkhbvdnGAUCRYWSMKHBVDN
15
+ +
16
+ DEFGHIDEFGHIDEFGHIDEFGHIDEFGHI
@@ -0,0 +1,16 @@
1
+ @FAKE0011 Original version has lower case unambiguous RNA with PHRED scores from 0 to 40 inclusive (in that order)
2
+ ACGUACGUACGUACGUACGUACGUACGUACGUACGUACGUA
3
+ +
4
+ ;;>@BCEFGHJKLMNOPQRSTUVWXYZ[\]^_`abcdefgh
5
+ @FAKE0012 Original version has mixed case unambiguous RNA with PHRED scores from 0 to 40 inclusive (in that order)
6
+ gUcauAGcgUcauAGcgUcauAGcgUcauAGcgUcauAGcg
7
+ +
8
+ ;;>@BCEFGHJKLMNOPQRSTUVWXYZ[\]^_`abcdefgh
9
+ @FAKE0013 Original version has lower case unambiguous RNA with PHRED scores from 0 to 40 inclusive (in that order)
10
+ ucagucagucagucagucagucagucagucagucagucagu
11
+ +
12
+ ;;>@BCEFGHJKLMNOPQRSTUVWXYZ[\]^_`abcdefgh
13
+ @FAKE0014 Original version has mixed case ambiguous RNA with PHRED scores from 35 to 40 inclusive (cycled)
14
+ gaucrywsmkhbvdnGAUCRYWSMKHBVDN
15
+ +
16
+ cdefghcdefghcdefghcdefghcdefgh
@@ -0,0 +1,16 @@
1
+ @FAKE0011 Original version has lower case unambiguous RNA with PHRED scores from 0 to 40 inclusive (in that order)
2
+ ACGUACGUACGUACGUACGUACGUACGUACGUACGUACGUA
3
+ +
4
+ !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHI
5
+ @FAKE0012 Original version has mixed case unambiguous RNA with PHRED scores from 0 to 40 inclusive (in that order)
6
+ gUcauAGcgUcauAGcgUcauAGcgUcauAGcgUcauAGcg
7
+ +
8
+ !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHI
9
+ @FAKE0013 Original version has lower case unambiguous RNA with PHRED scores from 0 to 40 inclusive (in that order)
10
+ ucagucagucagucagucagucagucagucagucagucagu
11
+ +
12
+ !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHI
13
+ @FAKE0014 Original version has mixed case ambiguous RNA with PHRED scores from 35 to 40 inclusive (cycled)
14
+ gaucrywsmkhbvdnGAUCRYWSMKHBVDN
15
+ +
16
+ DEFGHIDEFGHIDEFGHIDEFGHIDEFGHI
@@ -0,0 +1,8 @@
1
+ @FAKE0001 Original version has PHRED scores from 0 to 93 inclusive (in that order)
2
+ ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTAC
3
+ +
4
+ @ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]^_`abcdefghijklmnopqrstuvwxyz{|}~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
5
+ @FAKE0002 Original version has PHRED scores from 93 to 0 inclusive (in that order)
6
+ CATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCA
7
+ +
8
+ ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~}|{zyxwvutsrqponmlkjihgfedcba`_^]\[ZYXWVUTSRQPONMLKJIHGFEDCBA@
@@ -0,0 +1,8 @@
1
+ @FAKE0001 Original version has PHRED scores from 0 to 93 inclusive (in that order)
2
+ ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTAC
3
+ +
4
+ !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]^_`abcdefghijklmnopqrstuvwxyz{|}~
5
+ @FAKE0002 Original version has PHRED scores from 93 to 0 inclusive (in that order)
6
+ CATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCA
7
+ +
8
+ ~}|{zyxwvutsrqponmlkjihgfedcba`_^]\[ZYXWVUTSRQPONMLKJIHGFEDCBA@?>=<;:9876543210/.-,+*)('&%$#"!
@@ -0,0 +1,8 @@
1
+ @FAKE0001 Original version has PHRED scores from 0 to 93 inclusive (in that order)
2
+ ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTAC
3
+ +
4
+ ;;>@BCEFGHJKLMNOPQRSTUVWXYZ[\]^_`abcdefghijklmnopqrstuvwxyz{|}~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
5
+ @FAKE0002 Original version has PHRED scores from 93 to 0 inclusive (in that order)
6
+ CATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCA
7
+ +
8
+ ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~}|{zyxwvutsrqponmlkjihgfedcba`_^]\[ZYXWVUTSRQPONMLKJHGFECB@>;;
@@ -0,0 +1,8 @@
1
+ @FAKE0001 Original version has PHRED scores from 0 to 93 inclusive (in that order)
2
+ ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTAC
3
+ +
4
+ !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]^_`abcdefghijklmnopqrstuvwxyz{|}~
5
+ @FAKE0002 Original version has PHRED scores from 93 to 0 inclusive (in that order)
6
+ CATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCA
7
+ +
8
+ ~}|{zyxwvutsrqponmlkjihgfedcba`_^]\[ZYXWVUTSRQPONMLKJIHGFEDCBA@?>=<;:9876543210/.-,+*)('&%$#"!
@@ -0,0 +1,8 @@
1
+ @FAKE0003 Original version has Solexa scores from -5 to 62 inclusive (in that order)
2
+ ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT
3
+ +
4
+ AABBCCDDEEFGHIJJKLMNOPQRSTUVWXYZ[\]^_`abcdefghijklmnopqrstuvwxyz{|}~
5
+ @FAKE0004 Original version has Solexa scores from 62 to -5 inclusive (in that order)
6
+ TGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCA
7
+ +
8
+ ~}|{zyxwvutsrqponmlkjihgfedcba`_^]\[ZYXWVUTSRQPONMLKJJIHGFEEDDCCBBAA
@@ -0,0 +1,8 @@
1
+ @FAKE0003 Original version has Solexa scores from -5 to 62 inclusive (in that order)
2
+ ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT
3
+ +
4
+ ""##$$%%&&'()*++,-./0123456789:;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]^_
5
+ @FAKE0004 Original version has Solexa scores from 62 to -5 inclusive (in that order)
6
+ TGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCA
7
+ +
8
+ _^]\[ZYXWVUTSRQPONMLKJIHGFEDCBA@?>=<;:9876543210/.-,++*)('&&%%$$##""
@@ -0,0 +1,8 @@
1
+ @FAKE0003 Original version has Solexa scores from -5 to 62 inclusive (in that order)
2
+ ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT
3
+ +
4
+ ;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]^_`abcdefghijklmnopqrstuvwxyz{|}~
5
+ @FAKE0004 Original version has Solexa scores from 62 to -5 inclusive (in that order)
6
+ TGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCA
7
+ +
8
+ ~}|{zyxwvutsrqponmlkjihgfedcba`_^]\[ZYXWVUTSRQPONMLKJIHGFEDCBA@?>=<;
@@ -0,0 +1,8 @@
1
+ @FAKE0003 Original version has Solexa scores from -5 to 62 inclusive (in that order)
2
+ ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT
3
+ +
4
+ ;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]^_`abcdefghijklmnopqrstuvwxyz{|}~
5
+ @FAKE0004 Original version has Solexa scores from 62 to -5 inclusive (in that order)
6
+ TGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCA
7
+ +
8
+ ~}|{zyxwvutsrqponmlkjihgfedcba`_^]\[ZYXWVUTSRQPONMLKJIHGFEDCBA@?>=<;
@@ -0,0 +1,12 @@
1
+ @SRR014849.50939 EIXKN4201BA2EC length=135
2
+ GAAATTTCAGGGCCACCTTTTTTTTGATAGAATAATGGAGAAAATTAAAAGCTGTACATATACCAATGAACAATAAATCAATACATAAAAAAGGAGAAGTTGGAACCGAAAGGGTTTGAATTCAAACCCTTTCGG
3
+ +
4
+ Zb^Ld`N\[d`NaZ[aZc]UOKHDA[\YT[_W[aZ\aZ[Zd`SF_WeaUI[Y\[[\\\[\Z\aY`X[[aZ\aZ\d`OY[aY[[\[[e`WPJC^UZ[`X\[R]T_V_W[`[Ga\I`\H[[Q^TVa\Ia\Ic^LY\S
5
+ @SRR014849.110027 EIXKN4201APUB0 length=131
6
+ CTTCAAATGATTCCGGGACTGTTGGAACCGAAAGGGTTTGAATTCAAACCCTTTTCGGTTCCAACTCGCCGTCCGAATAATCCGTTCAAAATCTTGGCCTGTCAAAACGACTTTACGACCAGAACGATCCG
7
+ +
8
+ \aYY_[FY\T`X^Vd`OY\[[^U_V[R^T[_ZDc^La\HYYO\S[c^Ld`Nc_QAZaZaYaY`XZZ\[aZZ[aZ[aZ[aZY`Z[`ZWeaVJ\[aZaY`X[PY\eaUG[\[[d`OXTUZ[Q\\`W\\\Y_W\
9
+ @SRR014849.203935 EIXKN4201B4HU6 length=144
10
+ AACCCGTCCCATCAAAGATTTTGGTTGGAACCCGAAAGGGTTTTGAATTCAAACCCCTTTCGGTTCCAACTATTCAATTGTTTAACTTTTTTTAAATTGATGGTCTGTTGGACCATTTGTAATAATCCCCATCGGAATTTCTTT
11
+ +
12
+ `Z_ZDVT^YB[[Xd`PZ\d`RDaZaZ`ZaZ_ZDXd`Pd`Pd`RD[aZ`ZWd`Oc_RCd`P\aZ`ZaZaZY\YaZYaY`XYd`O`X[e`WPJEAc^LaZS[YYN[Z\Y`XWLT^U\b]JW[[RZ\SYc`RD[Z\WLXM`\HYa\I
@@ -0,0 +1,12 @@
1
+ @SRR014849.50939 EIXKN4201BA2EC length=135
2
+ GAAATTTCAGGGCCACCTTTTTTTTGATAGAATAATGGAGAAAATTAAAAGCTGTACATATACCAATGAACAATAAATCAATACATAAAAAAGGAGAAGTTGGAACCGAAAGGGTTTGAATTCAAACCCTTTCGG
3
+ +
4
+ ;C?-EA/=<EA/B;<B;D>60,)%"<=:5<@8<B;=B;<;EA4'@8FB6*<:=<<===<=;=B:A9<<B;=B;=EA0:<B:<<=<<FA81+$?6;<A9=<3>5@7@8<A<(B=*A=)<<2?57B=*B=*D?-:=4
5
+ @SRR014849.110027 EIXKN4201APUB0 length=131
6
+ CTTCAAATGATTCCGGGACTGTTGGAACCGAAAGGGTTTGAATTCAAACCCTTTTCGGTTCCAACTCGCCGTCCGAATAATCCGTTCAAAATCTTGGCCTGTCAAAACGACTTTACGACCAGAACGATCCG
7
+ +
8
+ =B::@<':=5A9?7EA0:=<<?6@7<3?5<@;%D?-B=)::0=4<D?-EA/D@2";B;B:B:A9;;=<B;;<B;<B;<B;:A;<A;8FB7+=<B;B:A9<1:=FB6(<=<<EA0956;<2==A8===:@8=
9
+ @SRR014849.203935 EIXKN4201B4HU6 length=144
10
+ AACCCGTCCCATCAAAGATTTTGGTTGGAACCCGAAAGGGTTTTGAATTCAAACCCCTTTCGGTTCCAACTATTCAATTGTTTAACTTTTTTTAAATTGATGGTCTGTTGGACCATTTGTAATAATCCCCATCGGAATTTCTTT
11
+ +
12
+ A;@;%75?:#<<9EA1;=EA3%B;B;A;B;@;%9EA1EA1EA3%<B;A;8EA0D@3$EA1=B;A;B;B;:=:B;:B:A9:EA0A9<FA81+&"D?-B;4<::/<;=:A98-5?6=C>+8<<3;=4:DA3%<;=8-9.A=):B=*
@@ -0,0 +1,12 @@
1
+ @SRR014849.50939 EIXKN4201BA2EC length=135
2
+ GAAATTTCAGGGCCACCTTTTTTTTGATAGAATAATGGAGAAAATTAAAAGCTGTACATATACCAATGAACAATAAATCAATACATAAAAAAGGAGAAGTTGGAACCGAAAGGGTTTGAATTCAAACCCTTTCGG
3
+ +
4
+ Zb^Ld`N\[d`NaZ[aZc]UOKGB;[\YT[_W[aZ\aZ[Zd`SE_WeaUH[Y\[[\\\[\Z\aY`X[[aZ\aZ\d`OY[aY[[\[[e`WPJ@^UZ[`X\[R]T_V_W[`[Fa\H`\G[[Q^TVa\Ha\Hc^LY\S
5
+ @SRR014849.110027 EIXKN4201APUB0 length=131
6
+ CTTCAAATGATTCCGGGACTGTTGGAACCGAAAGGGTTTGAATTCAAACCCTTTTCGGTTCCAACTCGCCGTCCGAATAATCCGTTCAAAATCTTGGCCTGTCAAAACGACTTTACGACCAGAACGATCCG
7
+ +
8
+ \aYY_[EY\T`X^Vd`OY\[[^U_V[R^T[_ZBc^La\GYYO\S[c^Ld`Nc_Q;ZaZaYaY`XZZ\[aZZ[aZ[aZ[aZY`Z[`ZWeaVJ\[aZaY`X[PY\eaUF[\[[d`OXTUZ[Q\\`W\\\Y_W\
9
+ @SRR014849.203935 EIXKN4201B4HU6 length=144
10
+ AACCCGTCCCATCAAAGATTTTGGTTGGAACCCGAAAGGGTTTTGAATTCAAACCCCTTTCGGTTCCAACTATTCAATTGTTTAACTTTTTTTAAATTGATGGTCTGTTGGACCATTTGTAATAATCCCCATCGGAATTTCTTT
11
+ +
12
+ `Z_ZBVT^Y>[[Xd`PZ\d`RBaZaZ`ZaZ_ZBXd`Pd`Pd`RB[aZ`ZWd`Oc_R@d`P\aZ`ZaZaZY\YaZYaY`XYd`O`X[e`WPJC;c^LaZS[YYN[Z\Y`XWLT^U\b]JW[[RZ\SYc`RB[Z\WLXM`\GYa\H
@@ -0,0 +1,24 @@
1
+ @SRR014849.50939 EIXKN4201BA2EC length=135
2
+ GAAATTTCAGGGCCACCTTTTTTTTGATAGAATAATGGAGAAAATTAAAAGCTGTACATATACCAATGAACAATAAATCAATACATAAAAAAGGAGAAGTTGGAACCGAAAGGGTTTGAATTCAAACCCTTTCGG
3
+ +
4
+ ;C?-EA/=<EA/B;<B;D>60,)%"<=:5<
5
+ @8<B;=B;<;EA4'@8FB6*<:=<<===<=
6
+ ;=B:A9<<B;=B;=EA0:<B:<<=<<FA81
7
+ +$?6;<A9=<3>5@7@8<A<(B=*A=)<<2
8
+ ?57B=*B=*D?-:=4
9
+ @SRR014849.110027 EIXKN4201APUB0 length=131
10
+ CTTCAAATGATTCCGGGACTGTTGGAACCGAAAGGGTTTGAATTCAAACCCTTTTCGGTTCCAACTCGCCGTCCGAATAATCCGTTCAAAATCTTGGCCTGTCAAAACGACTTTACGACCAGAACGATCCG
11
+ +
12
+ =B::@<':=5A9?7EA0:=<<?6@7<3?5<
13
+ @;%D?-B=)::0=4<D?-EA/D@2";B;B:
14
+ B:A9;;=<B;;<B;<B;<B;:A;<A;8FB7
15
+ +=<B;B:A9<1:=FB6(<=<<EA0956;<2
16
+ ==A8===:@8=
17
+ @SRR014849.203935 EIXKN4201B4HU6 length=144
18
+ AACCCGTCCCATCAAAGATTTTGGTTGGAACCCGAAAGGGTTTTGAATTCAAACCCCTTTCGGTTCCAACTATTCAATTGTTTAACTTTTTTTAAATTGATGGTCTGTTGGACCATTTGTAATAATCCCCATCGGAATTTCTTT
19
+ +
20
+ A;@;%75?:#<<9EA1;=EA3%B;B;A;B;
21
+ @;%9EA1EA1EA3%<B;A;8EA0D@3$EA1
22
+ =B;A;B;B;:=:B;:B:A9:EA0A9<FA81
23
+ +&"D?-B;4<::/<;=:A98-5?6=C>+8<
24
+ <3;=4:DA3%<;=8-9.A=):B=*
File without changes
File without changes
@@ -0,0 +1,13 @@
1
+ # All non-overlapping hits in all sequences.
2
+ # sequence_name motif hit_start hit_end hit_p-value
3
+ gi|33357914|pdb|1P85|M 6 54 74 3.70e-05
4
+ gi|14488684|pdb|1IHO|A 2 195 215 3.12e-05
5
+ gi|2624640|pdb|1HXQ|B 1 173 220 4.27e-05
6
+ gi|9954928|pdb|1EYZ|A 6 7 27 2.72e-05
7
+ gi|9954928|pdb|1EYZ|A 10 311 325 9.75e-05
8
+ gi|28948818|pdb|1NEK|A 2 29 49 8.96e-06
9
+ gi|85544130|pdb|2AVU|E 8 112 140 4.25e-05
10
+ gi|83754486|pdb|2C27|A 6 42 62 2.72e-05
11
+ gi|18655936|pdb|1KP9|A 8 92 120 3.96e-05
12
+ gi|88192540|pdb|2C4N|A 8 178 206 5.42e-05
13
+ gi|157831485|pdb|1IOV|A 3 130 150 6.63e-07
@@ -0,0 +1,3 @@
1
+ ********************************************************************************
2
+ MEME - Motif discovery tool
3
+ ********************************************************************************
@@ -0,0 +1,666 @@
1
+ <?xml version="1.0" encoding="UTF-8"?>
2
+ <phyloxml xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.phyloxml.org http://www.phyloxml.org/1.00/phyloxml.xsd" xmlns="http://www.phyloxml.org">
3
+ <phylogeny rooted="true">
4
+ <clade>
5
+ <clade>
6
+ <branch_length>0.18105</branch_length>
7
+ <confidence type="unknown">89.0</confidence>
8
+ <clade>
9
+ <branch_length>0.07466</branch_length>
10
+ <confidence type="unknown">32.0</confidence>
11
+ <clade>
12
+ <branch_length>0.26168</branch_length>
13
+ <confidence type="unknown">100.0</confidence>
14
+ <clade>
15
+ <branch_length>0.22058</branch_length>
16
+ <confidence type="unknown">89.0</confidence>
17
+ <clade>
18
+ <branch_length>0.28901</branch_length>
19
+ <confidence type="unknown">100.0</confidence>
20
+ <clade>
21
+ <branch_length>0.06584</branch_length>
22
+ <confidence type="unknown">100.0</confidence>
23
+ <clade>
24
+ <branch_length>0.02309</branch_length>
25
+ <confidence type="unknown">43.0</confidence>
26
+ <clade>
27
+ <branch_length>0.0746</branch_length>
28
+ <confidence type="unknown">100.0</confidence>
29
+ <clade>
30
+ <branch_length>0.02365</branch_length>
31
+ <confidence type="unknown">88.0</confidence>
32
+ <clade>
33
+ <name>22_MOUSE</name>
34
+ <branch_length>0.05998</branch_length>
35
+ <taxonomy>
36
+ <code>MOUSE</code>
37
+ </taxonomy>
38
+ <sequence>
39
+ <domain_architecture length="1249">
40
+ <domain from="6" to="90" confidence="7.0E-26">CARD</domain>
41
+ <domain from="109" to="414" confidence="7.2E-117">NB-ARC</domain>
42
+ <domain from="605" to="643" confidence="2.4E-6">WD40</domain>
43
+ <domain from="647" to="685" confidence="1.1E-12">WD40</domain>
44
+ <domain from="689" to="729" confidence="2.4E-7">WD40</domain>
45
+ <domain from="733" to="771" confidence="4.7E-14">WD40</domain>
46
+ <domain from="872" to="910" confidence="2.5E-8">WD40</domain>
47
+ <domain from="993" to="1031" confidence="4.6E-6">WD40</domain>
48
+ <domain from="1075" to="1113" confidence="6.3E-7">WD40</domain>
49
+ <domain from="1117" to="1155" confidence="1.4E-7">WD40</domain>
50
+ <domain from="1168" to="1204" confidence="0.3">WD40</domain>
51
+ </domain_architecture>
52
+ </sequence>
53
+ </clade>
54
+ <clade>
55
+ <name>Apaf-1_HUMAN</name>
56
+ <branch_length>0.01825</branch_length>
57
+ <taxonomy>
58
+ <code>HUMAN</code>
59
+ </taxonomy>
60
+ <sequence>
61
+ <domain_architecture length="1248">
62
+ <domain from="6" to="90" confidence="1.1E-25">CARD</domain>
63
+ <domain from="109" to="414" confidence="3.0E-134">NB-ARC</domain>
64
+ <domain from="605" to="643" confidence="8.5E-6">WD40</domain>
65
+ <domain from="647" to="685" confidence="2.5E-11">WD40</domain>
66
+ <domain from="689" to="729" confidence="2.4E-8">WD40</domain>
67
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83
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84
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100
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101
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104
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105
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106
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128
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130
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148
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150
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156
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157
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169
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171
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177
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188
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213
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214
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216
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217
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290
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+ <domain from="708" to="739" confidence="1.3">TPR_3</domain>
522
+ <domain from="708" to="733" confidence="0.16">TPR_4</domain>
523
+ <domain from="833" to="916" confidence="5.6E-14">Death</domain>
524
+ <domain from="846" to="868" confidence="0.36">LTXXQ</domain>
525
+ <domain from="930" to="1011" confidence="8.3E-17">Death</domain>
526
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527
+ </sequence>
528
+ </clade>
529
+ </clade>
530
+ <clade>
531
+ <branch_length>0.34914</branch_length>
532
+ <confidence type="unknown">98.0</confidence>
533
+ <clade>
534
+ <branch_length>0.22189</branch_length>
535
+ <confidence type="unknown">95.0</confidence>
536
+ <clade>
537
+ <name>3_BRAFL</name>
538
+ <branch_length>0.48766</branch_length>
539
+ <taxonomy>
540
+ <code>BRAFL</code>
541
+ </taxonomy>
542
+ <sequence>
543
+ <domain_architecture length="2080">
544
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545
+ <domain from="620" to="659" confidence="1.4E-6">WD40</domain>
546
+ <domain from="663" to="701" confidence="1.4E-8">WD40</domain>
547
+ <domain from="705" to="743" confidence="3.0E-11">WD40</domain>
548
+ <domain from="747" to="785" confidence="1.1E-8">WD40</domain>
549
+ <domain from="788" to="826" confidence="1.6E-5">WD40</domain>
550
+ <domain from="830" to="870" confidence="1.3E-4">WD40</domain>
551
+ <domain from="874" to="914" confidence="6.2E-9">WD40</domain>
552
+ <domain from="919" to="957" confidence="0.0011">WD40</domain>
553
+ <domain from="961" to="1000" confidence="1.8E-8">WD40</domain>
554
+ <domain from="1013" to="1051" confidence="1.3E-6">WD40</domain>
555
+ <domain from="1055" to="1092" confidence="0.096">WD40</domain>
556
+ <domain from="1794" to="1853" confidence="3.6E-4">Collagen</domain>
557
+ </domain_architecture>
558
+ </sequence>
559
+ </clade>
560
+ <clade>
561
+ <name>2_BRAFL</name>
562
+ <branch_length>0.65293</branch_length>
563
+ <taxonomy>
564
+ <code>BRAFL</code>
565
+ </taxonomy>
566
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567
+ <domain_architecture length="1691">
568
+ <domain from="162" to="457" confidence="4.4E-10">NB-ARC</domain>
569
+ <domain from="640" to="680" confidence="0.0068">WD40</domain>
570
+ <domain from="684" to="722" confidence="1.6E-8">WD40</domain>
571
+ <domain from="726" to="764" confidence="6.0E-9">WD40</domain>
572
+ <domain from="827" to="865" confidence="6.9E-10">WD40</domain>
573
+ <domain from="868" to="906" confidence="1.2E-6">WD40</domain>
574
+ <domain from="910" to="950" confidence="0.0080">WD40</domain>
575
+ <domain from="954" to="994" confidence="0.0016">WD40</domain>
576
+ <domain from="999" to="1037" confidence="4.9E-6">WD40</domain>
577
+ <domain from="1042" to="1080" confidence="6.3E-8">WD40</domain>
578
+ <domain from="1100" to="1138" confidence="1.9E-8">WD40</domain>
579
+ <domain from="1142" to="1178" confidence="1.4">WD40</domain>
580
+ <domain from="1577" to="1615" confidence="4.3E-4">WD40</domain>
581
+ </domain_architecture>
582
+ </sequence>
583
+ </clade>
584
+ </clade>
585
+ <clade>
586
+ <name>19_NEMVE</name>
587
+ <branch_length>0.57144</branch_length>
588
+ <taxonomy>
589
+ <code>NEMVE</code>
590
+ </taxonomy>
591
+ <sequence>
592
+ <domain_architecture length="1649">
593
+ <domain from="99" to="174" confidence="4.6E-7">DED</domain>
594
+ <domain from="181" to="503" confidence="8.0E-13">NB-ARC</domain>
595
+ <domain from="696" to="734" confidence="1.4E-8">WD40</domain>
596
+ <domain from="738" to="776" confidence="2.9E-9">WD40</domain>
597
+ <domain from="780" to="818" confidence="3.8E-10">WD40</domain>
598
+ <domain from="822" to="860" confidence="6.4E-9">WD40</domain>
599
+ <domain from="864" to="902" confidence="2.1E-10">WD40</domain>
600
+ <domain from="906" to="944" confidence="1.3E-8">WD40</domain>
601
+ <domain from="948" to="986" confidence="1.2E-8">WD40</domain>
602
+ <domain from="990" to="1028" confidence="9.4E-8">WD40</domain>
603
+ <domain from="1032" to="1070" confidence="6.0E-8">WD40</domain>
604
+ <domain from="1074" to="1112" confidence="2.6E-4">WD40</domain>
605
+ <domain from="1364" to="1597" confidence="1.9">SGL</domain>
606
+ <domain from="1442" to="1480" confidence="9.7E-7">WD40</domain>
607
+ <domain from="1527" to="1565" confidence="1.2">WD40</domain>
608
+ <domain from="1568" to="1606" confidence="1.1E-6">WD40</domain>
609
+ </domain_architecture>
610
+ </sequence>
611
+ </clade>
612
+ </clade>
613
+ </clade>
614
+ <clade>
615
+ <branch_length>0.43438</branch_length>
616
+ <confidence type="unknown">92.0</confidence>
617
+ <clade>
618
+ <branch_length>0.92214</branch_length>
619
+ <confidence type="unknown">100.0</confidence>
620
+ <clade>
621
+ <name>37_BRAFL</name>
622
+ <branch_length>0.21133</branch_length>
623
+ <taxonomy>
624
+ <code>BRAFL</code>
625
+ </taxonomy>
626
+ <sequence>
627
+ <domain_architecture length="1793">
628
+ <domain from="6" to="89" confidence="9.6E-13">CARD</domain>
629
+ <domain from="118" to="202" confidence="4.5E-9">CARD</domain>
630
+ <domain from="206" to="491" confidence="0.0011">NB-ARC</domain>
631
+ <domain from="238" to="388" confidence="0.0043">NACHT</domain>
632
+ </domain_architecture>
633
+ </sequence>
634
+ </clade>
635
+ <clade>
636
+ <name>36_BRAFL</name>
637
+ <branch_length>0.16225</branch_length>
638
+ <taxonomy>
639
+ <code>BRAFL</code>
640
+ </taxonomy>
641
+ <sequence>
642
+ <domain_architecture length="918">
643
+ <domain from="9" to="93" confidence="1.6E-9">CARD</domain>
644
+ <domain from="98" to="403" confidence="0.0019">NB-ARC</domain>
645
+ </domain_architecture>
646
+ </sequence>
647
+ </clade>
648
+ </clade>
649
+ <clade>
650
+ <name>33_BRAFL</name>
651
+ <branch_length>0.8363</branch_length>
652
+ <taxonomy>
653
+ <code>BRAFL</code>
654
+ </taxonomy>
655
+ <sequence>
656
+ <domain_architecture length="1212">
657
+ <domain from="5" to="87" confidence="4.7E-12">Death</domain>
658
+ <domain from="154" to="465" confidence="2.0E-6">NB-ARC</domain>
659
+ </domain_architecture>
660
+ </sequence>
661
+ </clade>
662
+ </clade>
663
+ </clade>
664
+ </clade>
665
+ </phylogeny>
666
+ </phyloxml>