bio-twobit 0.1.3 → 0.2.0
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- checksums.yaml +4 -4
- data/LICENSE.txt +11 -0
- data/README.md +42 -4
- data/ext/bio/twobit/twobit.c +409 -412
- data/lib/bio/twobit/cache_path.rb +32 -0
- data/lib/bio/twobit/downloader.rb +282 -0
- data/lib/bio/twobit/metadata.rb +9 -0
- data/lib/bio/twobit/reference_genome.rb +24 -0
- data/lib/bio/twobit/references/danrer10.rb +16 -0
- data/lib/bio/twobit/references/danrer11.rb +16 -0
- data/lib/bio/twobit/references/dm6.rb +16 -0
- data/lib/bio/twobit/references/hg19.rb +16 -0
- data/lib/bio/twobit/references/hg38.rb +16 -0
- data/lib/bio/twobit/references/hs1.rb +16 -0
- data/lib/bio/twobit/references/mm10.rb +16 -0
- data/lib/bio/twobit/references/mm39.rb +16 -0
- data/lib/bio/twobit/references/mm9.rb +16 -0
- data/lib/bio/twobit/version.rb +1 -1
- data/lib/bio/twobit.rb +55 -9
- metadata +16 -7
- data/.rubocop.yml +0 -13
- data/Gemfile +0 -14
- data/Rakefile +0 -25
- data/bio-twobit.gemspec +0 -25
@@ -0,0 +1,32 @@
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# https://github.com/red-data-tools/red-datasets/blob/master/lib/datasets/cache-path.rb
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module Bio
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class TwoBit
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class CachePath
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def initialize(id)
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@id = id
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end
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def base_dir
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Pathname(system_cache_dir).expand_path + "bio-twobit" + @id
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end
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def remove
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FileUtils.rmtree(base_dir.to_s, secure: true) if base_dir.exist?
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end
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private
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def system_cache_dir
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case RUBY_PLATFORM
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when /mswin/, /mingw/
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ENV["LOCALAPPDATA"] || "~/AppData/Local"
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when /darwin/
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"~/Library/Caches"
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else
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ENV["XDG_CACHE_HOME"] || "~/.cache"
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end
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end
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end
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end
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end
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# https://github.com/red-data-tools/red-datasets/blob/master/lib/datasets/downloader.rb
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require "fileutils"
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begin
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require "io/console"
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rescue LoadError
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end
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require "net/http"
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require "pathname"
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module Bio
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class TwoBit
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class Downloader
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class TooManyRedirects < StandardError; end
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def initialize(url)
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url = if url.is_a?(URI::Generic)
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url.dup
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else
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URI.parse(url)
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end
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@url = url
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return if @url.is_a?(URI::HTTP)
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raise ArgumentError, "download URL must be HTTP or HTTPS: <#{@url}>"
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end
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def download(output_path)
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return if output_path.exist?
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output_path.parent.mkpath
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headers = {
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"Accept-Encoding" => "identity",
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"User-Agent" => "BioTwobit/#{VERSION}"
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}
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start = nil
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partial_output_path = Pathname.new("#{output_path}.partial")
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if partial_output_path.exist?
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start = partial_output_path.size
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headers["Range"] = "bytes=#{start}-"
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end
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start_http(@url, headers) do |response|
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if response.is_a?(Net::HTTPPartialContent)
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mode = "ab"
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else
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start = nil
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mode = "wb"
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end
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base_name = @url.path.split("/").last
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size_current = 0
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size_max = response.content_length
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if start
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size_current += start
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size_max += start
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end
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progress_reporter = ProgressReporter.new(base_name, size_max)
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partial_output_path.open(mode) do |output|
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response.read_body do |chunk|
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size_current += chunk.bytesize
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progress_reporter.report(size_current)
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output.write(chunk)
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end
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end
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end
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FileUtils.mv(partial_output_path, output_path)
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rescue TooManyRedirects => e
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last_url = e.message[/\Atoo many redirections: (.+)\z/, 1]
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raise TooManyRedirects, "too many redirections: #{@url} .. #{last_url}"
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end
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private def start_http(url, headers, limit = 10, &block)
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raise TooManyRedirects, "too many redirections: #{url}" if limit == 0
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http = Net::HTTP.new(url.hostname, url.port)
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# http.set_debug_output($stderr)
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http.use_ssl = (url.scheme == "https")
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http.start do
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path = url.path
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path += "?#{url.query}" if url.query
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request = Net::HTTP::Get.new(path, headers)
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http.request(request) do |response|
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case response
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when Net::HTTPSuccess, Net::HTTPPartialContent
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return block.call(response)
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when Net::HTTPRedirection
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url = URI.parse(response[:location])
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warn "Redirect to #{url}"
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return start_http(url, headers, limit - 1, &block)
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else
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message = response.code
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message += ": #{response.message}" if response.message and !response.message.empty?
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message += ": #{url}"
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raise response.error_type.new(message, response)
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end
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end
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end
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end
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class ProgressReporter
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def initialize(base_name, size_max)
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@base_name = base_name
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@size_max = size_max
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@time_previous = Time.now
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@size_previous = 0
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@need_report = ($stderr == STDERR and $stderr.tty?)
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end
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def report(size_current)
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return unless @need_report
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return if @size_max.nil?
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return unless foreground?
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done = (size_current == @size_max)
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time_current = Time.now
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return if !done and time_current - @time_previous <= 1
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read_bytes = size_current - @size_previous
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throughput = read_bytes.to_f / (time_current - @time_previous)
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@time_previous = time_current
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@size_previous = size_current
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message = build_message(size_current, throughput)
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$stderr.print("\r#{message}") if message
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$stderr.puts if done
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end
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private
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def build_message(size_current, throughput)
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percent = (size_current / @size_max.to_f) * 100
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formatted_size = format("[%s/%s]", format_size(size_current), format_size(@size_max))
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rest_second = (@size_max - size_current) / throughput
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separator = " - "
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progress = format("%05.1f%% %s %s %s", percent, formatted_size, format_time_interval(rest_second),
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format_throughput(throughput))
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base_name = @base_name
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width = guess_terminal_width
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return "#{base_name}#{separator}#{progress}" if width.nil?
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return nil if progress.size > width
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base_name_width = width - progress.size - separator.size
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if base_name.size > base_name_width
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ellipsis = "..."
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shorten_base_name_width = base_name_width - ellipsis.size
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return progress if shorten_base_name_width < 1
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base_name = base_name[0, shorten_base_name_width] + ellipsis
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end
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"#{base_name}#{separator}#{progress}"
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end
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def format_size(size)
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if size < 1000
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"%d" % size
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elsif size < (1000**2)
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format("%6.2fKB", (size.to_f / 1000))
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elsif size < (1000**3)
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format("%6.2fMB", (size.to_f / (1000**2)))
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elsif size < (1000**4)
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format("%6.2fGB", (size.to_f / (1000**3)))
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else
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format("%.2fTB", (size.to_f / (1000**4)))
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end
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end
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def format_time_interval(interval)
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if interval < 60
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"00:00:%02d" % interval
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elsif interval < (60 * 60)
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minute, second = interval.divmod(60)
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format("00:%02d:%02d", minute, second)
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elsif interval < (60 * 60 * 24)
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minute, second = interval.divmod(60)
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hour, minute = minute.divmod(60)
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format("%02d:%02d:%02d", hour, minute, second)
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else
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minute, second = interval.divmod(60)
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hour, minute = minute.divmod(60)
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day, hour = hour.divmod(24)
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format("%dd %02d:%02d:%02d", day, hour, minute, second)
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end
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end
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def format_throughput(throughput)
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throughput_byte = throughput / 8
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if throughput_byte <= 1000
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"%3dB/s" % throughput_byte
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elsif throughput_byte <= (1000**2)
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format("%3dKB/s", (throughput_byte / 1000))
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elsif throughput_byte <= (1000**3)
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format("%3dMB/s", (throughput_byte / (1000**2)))
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else
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format("%3dGB/s", (throughput_byte / (1000**3)))
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end
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end
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def foreground?
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proc_stat_path = "/proc/self/stat"
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ps_path = "/bin/ps"
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if File.exist?(proc_stat_path)
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stat = File.read(proc_stat_path).sub(/\A.+\) /, "").split
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process_group_id = stat[2]
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terminal_process_group_id = stat[5]
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process_group_id == terminal_process_group_id
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elsif File.executable?(ps_path)
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IO.pipe do |input, output|
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pid = spawn(ps_path, "-o", "stat", "-p", Process.pid.to_s,
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{ out: output, err: output })
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output.close
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_, status = Process.waitpid2(pid)
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return false unless status.success?
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input.each_line.to_a.last.include?("+")
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end
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else
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false
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end
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end
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def guess_terminal_width
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guess_terminal_width_from_io ||
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guess_terminal_width_from_command ||
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guess_terminal_width_from_env ||
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80
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end
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def guess_terminal_width_from_io
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if IO.respond_to?(:console)
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IO.console.winsize[1]
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elsif $stderr.respond_to?(:winsize)
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begin
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$stderr.winsize[1]
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rescue SystemCallError
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nil
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end
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end
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end
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def guess_terminal_width_from_command
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IO.pipe do |input, output|
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begin
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pid = spawn("tput", "cols", { out: output, err: output })
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rescue SystemCallError
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return nil
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end
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output.close
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_, status = Process.waitpid2(pid)
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return nil unless status.success?
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result = input.read.chomp
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begin
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Integer(result, 10)
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rescue ArgumentError
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nil
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end
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end
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end
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def guess_terminal_width_from_env
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env = ENV["COLUMNS"] || ENV["TERM_WIDTH"]
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return nil if env.nil?
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begin
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Integer(env, 10)
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rescue ArgumentError
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nil
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end
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end
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end
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end
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end
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end
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module Bio
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class TwoBit
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class ReferenceGenome < TwoBit
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def self.open(*args, **kwargs, &block)
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raise ArgumentError, "#{self}#open() does not accept arguments" if args.any?
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super(**kwargs, &block)
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end
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def initialize(**kwargs)
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@local_name ||= File.basename(@data_url)
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super(prepare_data, **kwargs)
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end
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private
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def prepare_data
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data_path = cache_dir_path + @local_name
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download(data_path, @data_url)
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data_path
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end
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end
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end
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end
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@@ -0,0 +1,16 @@
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require_relative "../reference_genome"
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module Bio
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class TwoBit
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class DanRer10 < ReferenceGenome
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def initialize(**kwargs)
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@metadata = Metadata.new
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@metadata.id = "danRer10"
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@metadata.name = "danRer10"
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@metadata.url = "https://hgdownload.soe.ucsc.edu/downloads.html"
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@data_url = "https://hgdownload.soe.ucsc.edu/goldenPath/danRer10/bigZips/danRer10.2bit"
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super(**kwargs)
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end
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end
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end
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end
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@@ -0,0 +1,16 @@
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require_relative "../reference_genome"
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module Bio
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class TwoBit
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class DanRer11 < ReferenceGenome
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def initialize(**kwargs)
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@metadata = Metadata.new
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@metadata.id = "danRer11"
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@metadata.name = "danRer11"
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@metadata.url = "https://hgdownload.soe.ucsc.edu/downloads.html"
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@data_url = "https://hgdownload.soe.ucsc.edu/goldenPath/danRer11/bigZips/danRer11.2bit"
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+
super(**kwargs)
|
13
|
+
end
|
14
|
+
end
|
15
|
+
end
|
16
|
+
end
|
@@ -0,0 +1,16 @@
|
|
1
|
+
require_relative "../reference_genome"
|
2
|
+
|
3
|
+
module Bio
|
4
|
+
class TwoBit
|
5
|
+
class Dm6 < ReferenceGenome
|
6
|
+
def initialize(**kwargs)
|
7
|
+
@metadata = Metadata.new
|
8
|
+
@metadata.id = "dm6"
|
9
|
+
@metadata.name = "dm6"
|
10
|
+
@metadata.url = "https://hgdownload.soe.ucsc.edu/downloads.html"
|
11
|
+
@data_url = "https://hgdownload.soe.ucsc.edu/goldenPath/dm6/bigZips/dm6.2bit"
|
12
|
+
super(**kwargs)
|
13
|
+
end
|
14
|
+
end
|
15
|
+
end
|
16
|
+
end
|
@@ -0,0 +1,16 @@
|
|
1
|
+
require_relative "../reference_genome"
|
2
|
+
|
3
|
+
module Bio
|
4
|
+
class TwoBit
|
5
|
+
class Hg19 < ReferenceGenome
|
6
|
+
def initialize(**kwargs)
|
7
|
+
@metadata = Metadata.new
|
8
|
+
@metadata.id = "hg19"
|
9
|
+
@metadata.name = "hg19"
|
10
|
+
@metadata.url = "https://hgdownload.soe.ucsc.edu/downloads.html"
|
11
|
+
@data_url = "https://hgdownload.soe.ucsc.edu/goldenPath/hg19/bigZips/hg19.2bit"
|
12
|
+
super(**kwargs)
|
13
|
+
end
|
14
|
+
end
|
15
|
+
end
|
16
|
+
end
|
@@ -0,0 +1,16 @@
|
|
1
|
+
require_relative "../reference_genome"
|
2
|
+
|
3
|
+
module Bio
|
4
|
+
class TwoBit
|
5
|
+
class Hg38 < ReferenceGenome
|
6
|
+
def initialize(**kwargs)
|
7
|
+
@metadata = Metadata.new
|
8
|
+
@metadata.id = "hg38"
|
9
|
+
@metadata.name = "hg38"
|
10
|
+
@metadata.url = "https://hgdownload.soe.ucsc.edu/downloads.html"
|
11
|
+
@data_url = "https://hgdownload.soe.ucsc.edu/goldenPath/hg38/bigZips/hg38.2bit"
|
12
|
+
super(**kwargs)
|
13
|
+
end
|
14
|
+
end
|
15
|
+
end
|
16
|
+
end
|
@@ -0,0 +1,16 @@
|
|
1
|
+
require_relative "../reference_genome"
|
2
|
+
|
3
|
+
module Bio
|
4
|
+
class TwoBit
|
5
|
+
class Hs1 < ReferenceGenome
|
6
|
+
def initialize(**kwargs)
|
7
|
+
@metadata = Metadata.new
|
8
|
+
@metadata.id = "hs1"
|
9
|
+
@metadata.name = "hs1"
|
10
|
+
@metadata.url = "https://hgdownload.soe.ucsc.edu/downloads.html"
|
11
|
+
@data_url = "https://hgdownload.soe.ucsc.edu/goldenPath/hs1/bigZips/hs1.2bit"
|
12
|
+
super(**kwargs)
|
13
|
+
end
|
14
|
+
end
|
15
|
+
end
|
16
|
+
end
|
@@ -0,0 +1,16 @@
|
|
1
|
+
require_relative "../reference_genome"
|
2
|
+
|
3
|
+
module Bio
|
4
|
+
class TwoBit
|
5
|
+
class Mm10 < ReferenceGenome
|
6
|
+
def initialize(**kwargs)
|
7
|
+
@metadata = Metadata.new
|
8
|
+
@metadata.id = "mm10"
|
9
|
+
@metadata.name = "mm10"
|
10
|
+
@metadata.url = "https://hgdownload.soe.ucsc.edu/downloads.html"
|
11
|
+
@data_url = "https://hgdownload.soe.ucsc.edu/goldenPath/mm10/bigZips/mm10.2bit"
|
12
|
+
super(**kwargs)
|
13
|
+
end
|
14
|
+
end
|
15
|
+
end
|
16
|
+
end
|
@@ -0,0 +1,16 @@
|
|
1
|
+
require_relative "../reference_genome"
|
2
|
+
|
3
|
+
module Bio
|
4
|
+
class TwoBit
|
5
|
+
class Mm39 < ReferenceGenome
|
6
|
+
def initialize(**kwargs)
|
7
|
+
@metadata = Metadata.new
|
8
|
+
@metadata.id = "mm39"
|
9
|
+
@metadata.name = "mm39"
|
10
|
+
@metadata.url = "https://hgdownload.soe.ucsc.edu/downloads.html"
|
11
|
+
@data_url = "https://hgdownload.soe.ucsc.edu/goldenPath/mm39/bigZips/mm39.2bit"
|
12
|
+
super(**kwargs)
|
13
|
+
end
|
14
|
+
end
|
15
|
+
end
|
16
|
+
end
|
@@ -0,0 +1,16 @@
|
|
1
|
+
require_relative "../reference_genome"
|
2
|
+
|
3
|
+
module Bio
|
4
|
+
class TwoBit
|
5
|
+
class Mm9 < ReferenceGenome
|
6
|
+
def initialize(**kwargs)
|
7
|
+
@metadata = Metadata.new
|
8
|
+
@metadata.id = "mm9"
|
9
|
+
@metadata.name = "mm9"
|
10
|
+
@metadata.url = "https://hgdownload.soe.ucsc.edu/downloads.html"
|
11
|
+
@data_url = "https://hgdownload.soe.ucsc.edu/goldenPath/mm9/bigZips/mm9.2bit"
|
12
|
+
super(**kwargs)
|
13
|
+
end
|
14
|
+
end
|
15
|
+
end
|
16
|
+
end
|
data/lib/bio/twobit/version.rb
CHANGED
data/lib/bio/twobit.rb
CHANGED
@@ -1,26 +1,51 @@
|
|
1
1
|
# frozen_string_literal: true
|
2
2
|
|
3
|
+
require "pathname"
|
3
4
|
require_relative "twobit/version"
|
4
5
|
require_relative "twobit/twobit"
|
6
|
+
require_relative "twobit/cache_path"
|
7
|
+
require_relative "twobit/downloader"
|
8
|
+
require_relative "twobit/metadata"
|
5
9
|
|
6
10
|
module Bio
|
7
11
|
# Reader for .2bit files (i.e., from UCSC genome browser)
|
8
12
|
class TwoBit
|
9
|
-
|
10
|
-
|
11
|
-
|
12
|
-
|
13
|
-
|
14
|
-
|
15
|
-
|
16
|
-
|
13
|
+
attr_reader :metadata
|
14
|
+
|
15
|
+
class << self
|
16
|
+
def open(*args, **kwargs)
|
17
|
+
file = new(*args, **kwargs)
|
18
|
+
return file unless block_given?
|
19
|
+
|
20
|
+
begin
|
21
|
+
yield file
|
22
|
+
ensure
|
23
|
+
file.close
|
24
|
+
end
|
25
|
+
file
|
26
|
+
end
|
27
|
+
|
28
|
+
# Here, const_missing is used instead of autoload.
|
29
|
+
|
30
|
+
def const_missing(name)
|
31
|
+
# prevents const_get from being called recursively many times.
|
32
|
+
@missing_const ||= []
|
33
|
+
super if @missing_const.include? name
|
34
|
+
@missing_const << name
|
35
|
+
|
36
|
+
path = File.join(__dir__, "twobit/references", "#{name.to_s.downcase}.rb")
|
37
|
+
if File.exist?(path)
|
38
|
+
require path
|
39
|
+
return const_get(name)
|
40
|
+
end
|
41
|
+
super
|
17
42
|
end
|
18
|
-
file
|
19
43
|
end
|
20
44
|
|
21
45
|
def initialize(fname, masked: false)
|
22
46
|
raise "TwoBit::new() does not take block; use TwoBit::open() instead" if block_given?
|
23
47
|
|
48
|
+
fname = fname.to_path if fname.respond_to?(:to_path)
|
24
49
|
@fname = fname
|
25
50
|
if masked
|
26
51
|
mskd = 1
|
@@ -49,6 +74,8 @@ module Bio
|
|
49
74
|
sequence_raw(chrom, start, stop)
|
50
75
|
end
|
51
76
|
|
77
|
+
alias seq sequence
|
78
|
+
|
52
79
|
def bases(chrom, start = 0, stop = 0, fraction: true)
|
53
80
|
raise ArgumentError, "negative start position" if start.negative?
|
54
81
|
raise ArgumentError, "negative stop position" if stop.negative?
|
@@ -69,5 +96,24 @@ module Bio
|
|
69
96
|
|
70
97
|
soft_masked_blocks_raw(chrom, start, stop)
|
71
98
|
end
|
99
|
+
|
100
|
+
def clear_cache!
|
101
|
+
cache_path.remove
|
102
|
+
end
|
103
|
+
|
104
|
+
private
|
105
|
+
|
106
|
+
def cache_dir_path
|
107
|
+
cache_path.base_dir
|
108
|
+
end
|
109
|
+
|
110
|
+
def cache_path
|
111
|
+
@cache_path ||= CachePath.new(@metadata.id)
|
112
|
+
end
|
113
|
+
|
114
|
+
def download(output_path, url)
|
115
|
+
downloader = Downloader.new(url)
|
116
|
+
downloader.download(output_path)
|
117
|
+
end
|
72
118
|
end
|
73
119
|
end
|
metadata
CHANGED
@@ -1,14 +1,14 @@
|
|
1
1
|
--- !ruby/object:Gem::Specification
|
2
2
|
name: bio-twobit
|
3
3
|
version: !ruby/object:Gem::Version
|
4
|
-
version: 0.
|
4
|
+
version: 0.2.0
|
5
5
|
platform: ruby
|
6
6
|
authors:
|
7
7
|
- kojix2
|
8
8
|
autorequire:
|
9
9
|
bindir: bin
|
10
10
|
cert_chain: []
|
11
|
-
date:
|
11
|
+
date: 2023-01-11 00:00:00.000000000 Z
|
12
12
|
dependencies: []
|
13
13
|
description: This is a Ruby binding for lib2bit(https://github.com/dpryan79/lib2bit),
|
14
14
|
which provides high-speed access to genomic data in 2bit file format.
|
@@ -19,12 +19,8 @@ extensions:
|
|
19
19
|
- ext/bio/twobit/extconf.rb
|
20
20
|
extra_rdoc_files: []
|
21
21
|
files:
|
22
|
-
- ".rubocop.yml"
|
23
|
-
- Gemfile
|
24
22
|
- LICENSE.txt
|
25
23
|
- README.md
|
26
|
-
- Rakefile
|
27
|
-
- bio-twobit.gemspec
|
28
24
|
- ext/bio/twobit/2bit.c
|
29
25
|
- ext/bio/twobit/2bit.h
|
30
26
|
- ext/bio/twobit/LICENSE
|
@@ -32,6 +28,19 @@ files:
|
|
32
28
|
- ext/bio/twobit/twobit.c
|
33
29
|
- ext/bio/twobit/twobit.h
|
34
30
|
- lib/bio/twobit.rb
|
31
|
+
- lib/bio/twobit/cache_path.rb
|
32
|
+
- lib/bio/twobit/downloader.rb
|
33
|
+
- lib/bio/twobit/metadata.rb
|
34
|
+
- lib/bio/twobit/reference_genome.rb
|
35
|
+
- lib/bio/twobit/references/danrer10.rb
|
36
|
+
- lib/bio/twobit/references/danrer11.rb
|
37
|
+
- lib/bio/twobit/references/dm6.rb
|
38
|
+
- lib/bio/twobit/references/hg19.rb
|
39
|
+
- lib/bio/twobit/references/hg38.rb
|
40
|
+
- lib/bio/twobit/references/hs1.rb
|
41
|
+
- lib/bio/twobit/references/mm10.rb
|
42
|
+
- lib/bio/twobit/references/mm39.rb
|
43
|
+
- lib/bio/twobit/references/mm9.rb
|
35
44
|
- lib/bio/twobit/version.rb
|
36
45
|
homepage: https://github.com/ruby-on-bioc/bio-twobit
|
37
46
|
licenses:
|
@@ -52,7 +61,7 @@ required_rubygems_version: !ruby/object:Gem::Requirement
|
|
52
61
|
- !ruby/object:Gem::Version
|
53
62
|
version: '0'
|
54
63
|
requirements: []
|
55
|
-
rubygems_version: 3.
|
64
|
+
rubygems_version: 3.4.1
|
56
65
|
signing_key:
|
57
66
|
specification_version: 4
|
58
67
|
summary: A ruby library for accessing 2bit files
|
data/.rubocop.yml
DELETED